pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/905-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! epithelial to mesenchymal transition GO:0001837 28 15 3,000 3,378E-08 8,128E-05 ! positive regulation of ossification GO:0045778 47 20 3,000 1,189E-07 1,43E-04 ! positive regulation of bone remodeling GO:0046852 51 22 3,000 1,789E-07 1,434E-04 GO:0034105|positive regulation of tissue remodeling, ! salivary gland morphogenesis GO:0007435 13 6 2,000 2,29E-07 1,378E-04 ! SMAD protein nuclear translocation GO:0007184 20 10 2,000 1,365E-06 6,57E-04 ! salivary gland development GO:0007431 27 10 2,000 1,365E-06 5,475E-04 ! mesenchymal cell development GO:0014031 87 40 3,000 2,166E-06 7,446E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! gland morphogenesis GO:0022612 29 12 2,000 2,495E-06 7,503E-04 ! exocrine system development GO:0035272 32 13 2,000 3,238E-06 8,656E-04 ! positive regulation of bone mineralization GO:0030501 29 14 2,000 4,114E-06 9,899E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 4,114E-06 8,999E-04 GO:0060675|ureteric bud morphogenesis, ! positive regulation of biomineral formation GO:0070169 30 15 2,000 5,134E-06 1,029E-03 ! dopamine metabolic process GO:0042417 35 15 2,000 5,134E-06 9,502E-04 ! regulation of ossification GO:0030278 117 50 3,000 5,366E-06 9,221E-04 ! regulation of bone remodeling GO:0046850 137 57 3,000 9,093E-06 1,458E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 2,000 9,163E-06 1,378E-03 ! regulation of tissue remodeling GO:0034103 140 58 3,000 9,749E-06 1,38E-03 ! ureteric bud development GO:0001657 43 22 2,000 1,718E-05 2,296E-03 ! regulation of bone mineralization GO:0030500 49 23 2,000 1,972E-05 2,498E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 2,25E-05 2,707E-03 ! regulation of biomineral formation GO:0070167 51 25 2,000 2,553E-05 2,925E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 3,33E-05 3,642E-03 ! response to hypoxia GO:0001666 171 81 3,000 3,675E-05 3,844E-03 ! catechol metabolic process GO:0009712 54 29 2,000 4,03E-05 4,04E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to oxygen levels GO:0070482 176 83 3,000 4,045E-05 3,893E-03 ! phenol metabolic process GO:0018958 55 30 2,000 4,47E-05 4,136E-03 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 5,15E-05 4,589E-03 GO:0051489|regulation of filopodium assembly, ! muscle cell proliferation GO:0033002 11 5 1,000 5,15E-05 4,425E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 5,15E-05 4,273E-03 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 11 5 1,000 5,15E-05 4,13E-03 ! stem cell division GO:0017145 11 5 1,000 5,15E-05 3,997E-03 GO:0048103|somatic stem cell division, ! epithelial cell proliferation GO:0050673 9 5 1,000 5,15E-05 3,872E-03 ! spindle organization GO:0007051 46 32 2,000 5,443E-05 3,968E-03 ! metanephros development GO:0001656 74 32 2,000 5,443E-05 3,852E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 6,317E-05 4,342E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 7,714E-05 5,155E-03 ! glucocorticoid metabolic process GO:0008211 9 6 1,000 7,714E-05 5,016E-03 ! regulation of dendrite development GO:0050773 16 6 1,000 7,714E-05 4,884E-03 ! positive regulation of cell development GO:0010720 80 36 2,000 7,784E-05 4,802E-03 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 2,000 9,167E-05 5,514E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,078E-04 6,328E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,078E-04 6,177E-03 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 1,078E-04 6,034E-03 GO:0031958|corticosteroid receptor signaling pathway, ! dopamine biosynthetic process GO:0042416 18 7 1,000 1,078E-04 5,896E-03 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 1,425E-04 7,619E-03 ! ER overload response GO:0006983 12 8 1,000 1,436E-04 7,509E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,436E-04 7,349E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 1,436E-04 7,196E-03 ! hormone catabolic process GO:0042447 17 8 1,000 1,436E-04 7,049E-03 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 1,524E-04 7,335E-03 ! cell growth GO:0016049 84 45 2,000 1,524E-04 7,191E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 1,843E-04 8,528E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,843E-04 8,367E-03 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,843E-04 8,212E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 1,849E-04 8,088E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,088E-04 8,972E-03 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 2,215E-04 9,35E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 2,3E-04 9,543E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,3E-04 9,381E-03 ! positive regulation of heart contraction GO:0045823 16 10 1,000 2,3E-04 9,225E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 2,3E-04 9,073E-03 GO:0045685|regulation of glial cell differentiation, ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 2,3E-04 8,927E-03 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 2,347E-04 8,963E-03 ! heart morphogenesis GO:0003007 97 55 2,000 2,772E-04 0,01042235 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,807E-04 0,01039193 ! cardiac cell differentiation GO:0035051 31 11 1,000 2,807E-04 0,01023447 ! negative regulation of cell projection organization GO:0031345 37 12 1,000 3,364E-04 0,01208015 ! regulation of cell projection assembly GO:0060491 30 12 1,000 3,364E-04 0,0119025 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 3,364E-04 0,01173 ! positive regulation of cell growth GO:0030307 22 12 1,000 3,364E-04 0,01156243 ! mitotic spindle organization GO:0007052 21 12 1,000 3,364E-04 0,01139957 ! histone acetylation GO:0016573 26 12 1,000 3,364E-04 0,01124125 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,364E-04 0,01108726 ! kidney development GO:0001822 122 60 2,000 3,587E-04 0,01166156 ! regulation of epidermis development GO:0045682 19 13 1,000 3,97E-04 0,01273482 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,624E-04 0,01464009 ! hair follicle morphogenesis GO:0031069 26 14 1,000 4,624E-04 0,01444996 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 4,624E-04 0,0142647 ! regulation of cellular response to stress GO:0080135 128 67 2,000 4,964E-04 0,01511772 ! activation of MAPK activity GO:0000187 115 67 2,000 4,964E-04 0,01492875 ! positive regulation of cell size GO:0045793 27 15 1,000 5,328E-04 0,01582621 ! urogenital system development GO:0001655 137 69 2,000 5,411E-04 0,01587739 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 5,884E-04 0,01705559 ! bone remodeling GO:0046849 27 16 1,000 6,08E-04 0,01741531 ! regulation of neurotransmitter secretion GO:0046928 33 16 1,000 6,08E-04 0,01721043 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 6,08E-04 0,01701031 GO:0031114|regulation of microtubule depolymerization, ! regulation of dephosphorylation GO:0035303 43 16 1,000 6,08E-04 0,01681479 ! negative regulation of immune response GO:0050777 35 16 1,000 6,08E-04 0,01662371 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 6,08E-04 0,01643692 ! neutrophil chemotaxis GO:0030593 27 17 1,000 6,881E-04 0,01839427 ! steroid catabolic process GO:0006706 31 17 1,000 6,881E-04 0,01819214 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 6,881E-04 0,01799439 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,729E-04 0,01999639 ! epidermis morphogenesis GO:0048730 40 18 1,000 7,729E-04 0,01978366 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 7,729E-04 0,01957541 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 7,729E-04 0,0193715 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 7,729E-04 0,0191718 ! regulation of synaptic transmission GO:0050804 134 79 2,000 8,035E-04 0,01972627 ! protein import into nucleus GO:0006606 158 80 2,000 8,334E-04 0,02025467 ! pigmentation during development GO:0048066 41 19 1,000 8,626E-04 0,02075373 ! proximal/distal pattern formation GO:0009954 32 19 1,000 8,626E-04 0,02054825 ! lipid phosphorylation GO:0046834 35 19 1,000 8,626E-04 0,0203468 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 8,626E-04 0,02014926 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 8,626E-04 0,01995551 ! nuclear import GO:0051170 161 81 2,000 8,641E-04 0,01979939 ! protein amino acid acetylation GO:0006473 39 20 1,000 9,57E-04 0,02172226 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 9,57E-04 0,02151925 ! peptidyl-serine modification GO:0018209 43 20 1,000 9,57E-04 0,02132 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 9,603E-04 0,02119604 ! tube morphogenesis GO:0035239 176 86 2,000 1,028E-03 0,02248511 ! regulation of neurotransmitter transport GO:0051588 42 21 1,000 1,056E-03 0,02289343 ! collagen fibril organization GO:0030199 59 21 1,000 1,056E-03 0,02268902 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 1,056E-03 0,02248824 ! protein localization in nucleus GO:0034504 176 87 2,000 1,063E-03 0,02243435 ! gland development GO:0048732 206 88 2,000 1,099E-03 0,02298661 ! regulation of neurological system process GO:0031644 148 88 2,000 1,099E-03 0,02278845 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 1,135E-03 0,02334367 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,16E-03 0,02365385 ! activation of JUN kinase activity GO:0007257 42 22 1,000 1,16E-03 0,02345508 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,16E-03 0,02325962 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,269E-03 0,02522694 ! biogenic amine metabolic process GO:0006576 155 94 2,000 1,329E-03 0,02620937 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,5E-03 0,02934004 ! negative regulation of cell development GO:0010721 73 25 1,000 1,5E-03 0,02910343 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 1,5E-03 0,0288706 ! molting cycle process GO:0022404 50 26 1,000 1,623E-03 0,03098241 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 1,623E-03 0,03073845 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,623E-03 0,03049831 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,623E-03 0,03026189 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 1,623E-03 0,0300291 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 1,623E-03 0,02979987 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 1,623E-03 0,02957412 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 1,75E-03 0,03165306 ! protein amino acid acylation GO:0043543 55 27 1,000 1,75E-03 0,03141684 ! dendrite development GO:0016358 59 28 1,000 1,882E-03 0,0335333 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,882E-03 0,03328673 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,882E-03 0,03304376 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 1,882E-03 0,03280431 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 2,018E-03 0,03492911 ! BMP signaling pathway GO:0030509 64 32 1,000 2,454E-03 0,04217983 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 2,609E-03 0,04451686 ! leukocyte chemotaxis GO:0030595 50 33 1,000 2,609E-03 0,04420336 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 2,768E-03 0,04656881 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 2,931E-03 0,0489758 ! odontogenesis GO:0042476 66 35 1,000 2,931E-03 0,04863803 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 2,931E-03 0,04830489 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 2,931E-03 0,04797629 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,931E-03 0,04765213 ! tissue remodeling GO:0048771 76 37 1,000 3,271E-03 0,05282418 ! regulation of protein stability GO:0031647 73 37 1,000 3,271E-03 0,05247202 ! glycogen metabolic process GO:0005977 61 37 1,000 3,271E-03 0,05212452 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 3,271E-03 0,0517816 ! regulation of neuron projection development GO:0010975 91 38 1,000 3,448E-03 0,05422102 ! glucan metabolic process GO:0044042 62 38 1,000 3,448E-03 0,05386894 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 3,629E-03 0,05633126 ! segmentation GO:0035282 67 39 1,000 3,629E-03 0,05597016 ! gliogenesis GO:0042063 88 41 1,000 4,004E-03 0,06136147 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 4,198E-03 0,0639274 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 4,198E-03 0,06352535 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 4,198E-03 0,06312831 ! energy reserve metabolic process GO:0006112 74 43 1,000 4,396E-03 0,06569956 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 4,396E-03 0,06529401 ! leukocyte migration GO:0050900 68 45 1,000 4,806E-03 0,07093615 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 5,017E-03 0,07359976 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 5,017E-03 0,0731537 ! pigmentation GO:0043473 100 46 1,000 5,017E-03 0,07271302 ! response to insulin stimulus GO:0032868 95 46 1,000 5,017E-03 0,07227761 ! positive regulation of protein transport GO:0051222 72 46 1,000 5,017E-03 0,07184738 ! JNK cascade GO:0007254 91 47 1,000 5,232E-03 0,07448672 ! regulation of JNK cascade GO:0046328 94 47 1,000 5,232E-03 0,07404857 ! positive regulation of DNA binding GO:0043388 73 47 1,000 5,232E-03 0,07361553 ! positive regulation of cell cycle GO:0045787 89 48 1,000 5,451E-03 0,07625716 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 5,675E-03 0,07892623 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 5,675E-03 0,07847264 ! histone modification GO:0016570 91 50 1,000 5,903E-03 0,0811556 ! negative regulation of immune system process GO:0002683 95 50 1,000 5,903E-03 0,08069449 ! positive regulation of binding GO:0051099 78 51 1,000 6,135E-03 0,08339073 ! response to estrogen stimulus GO:0043627 93 51 1,000 6,135E-03 0,08292225 ! embryonic skeletal system development GO:0048706 85 51 1,000 6,135E-03 0,08245899 ! positive regulation of growth GO:0045927 90 52 1,000 6,371E-03 0,08515544 ! covalent chromatin modification GO:0016569 101 52 1,000 6,371E-03 0,08468497 ! cartilage development GO:0051216 90 52 1,000 6,371E-03 0,08421967 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 6,611E-03 0,08691608 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 6,855E-03 0,08963643 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 6,855E-03 0,08915191 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 7,103E-03 0,09188341 ! positive regulation of cell migration GO:0030335 126 57 1,000 7,612E-03 0,09793475 ! lipid modification GO:0030258 97 57 1,000 7,612E-03 0,09741382 ! regulation of intracellular transport GO:0032386 101 57 1,000 7,612E-03 0,09689841 ! skeletal system morphogenesis GO:0048705 105 59 1,000 8,136E-03 0,10303016 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 8,136E-03 0,10249074 ! regulation of heart contraction GO:0008016 110 60 1,000 8,404E-03 0,1053177 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 8,404E-03 0,10477201 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 8,404E-03 0,10423195 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 8,677E-03 0,10705508 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 9,233E-03 0,11333401 ! positive regulation of cell motion GO:0051272 146 64 1,000 9,516E-03 0,11622516 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 9,804E-03 0,11913405 GO:0035113|embryonic appendage morphogenesis, ! extracellular matrix organization GO:0030198 133 66 1,000 0,01009558 0,12206017 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,01039094 0,12500305 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01039094 0,12438115 ! lung development GO:0030324 144 67 1,000 0,01039094 0,1237654 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01069011 0,1267015 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01099307 0,1296535 ! appendage morphogenesis GO:0035107 135 70 1,000 0,01129979 0,13262095 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,01129979 0,13197715 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01140371 0,13254745 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01140371 0,1319102 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01140371 0,13127905 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01140371 0,13065392 ! neuron fate determination GO:0048664 7 5 0,000 0,01140371 0,1300347 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01140371 0,12942133 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01140371 0,12881372 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01140371 0,12821179 ! polyol transport GO:0015791 12 5 0,000 0,01140371 0,12761545 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01140371 0,12702464 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01140371 0,12643927 ! response to superoxide GO:0000303 10 5 0,000 0,01140371 0,12585928 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01140371 0,12528458 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01140371 0,1247151 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01140371 0,12415078 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01140371 0,12359154 ! female meiosis GO:0007143 7 5 0,000 0,01140371 0,12303732 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01140371 0,12248805 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01140371 0,12194366 ! cobalt ion transport GO:0006824 11 5 0,000 0,01140371 0,12140408 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01140371 0,12086926 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01140371 0,12033913 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01140371 0,11981364 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01140371 0,11929271 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01140371 0,11877629 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01140371 0,11826432 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01140371 0,11775675 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01140371 0,11725351 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01140371 0,11675456 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01140371 0,11625984 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01140371 0,11576929 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01140371 0,11528287 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01140371 0,11480051 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01140371 0,11432218 ! negative chemotaxis GO:0050919 14 5 0,000 0,01140371 0,11384781 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01140371 0,11337737 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01140371 0,11291079 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01140371 0,11244804 ! behavioral response to pain GO:0048266 9 5 0,000 0,01140371 0,11198907 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01140371 0,11153383 ! Notch receptor processing GO:0007220 8 5 0,000 0,01140371 0,11108228 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01140371 0,11063436 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01140371 0,11019005 ! micturition GO:0060073 9 5 0,000 0,01140371 0,10974929 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01140371 0,10931204 ! copulation GO:0007620 9 5 0,000 0,01140371 0,10887826 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01140371 0,10844791 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01140371 0,10802095 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01140371 0,10759734 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01140371 0,10717704 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01140371 0,10676001 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01140371 0,10634621 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01140371 0,10593561 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01140371 0,10552816 ! grooming behavior GO:0007625 6 5 0,000 0,01140371 0,10512384 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01140371 0,1047226 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01140371 0,10432442 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01140371 0,10392925 ! response to protozoan GO:0001562 10 5 0,000 0,01140371 0,10353707 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01140371 0,10314783 ! lymph vessel development GO:0001945 10 5 0,000 0,01140371 0,10276151 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01140371 0,10237807 ! endochondral ossification GO:0001958 16 5 0,000 0,01140371 0,10199748 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01140371 0,10161971 ! parathyroid gland development GO:0060017 13 5 0,000 0,01140371 0,10124473 ! anagen GO:0042640 6 5 0,000 0,01140371 0,10087251 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01140371 0,10050301 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01140371 0,10013621 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01140371 0,09977208 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01140371 0,09941059 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01140371 0,09905171 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01140371 0,0986954 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01140371 0,09834166 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01140371 0,09799044 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01140371 0,09764172 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01140371 0,09729547 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01140371 0,09695167 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01140371 0,09661029 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01140371 0,09627131 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01140371 0,09593469 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01140371 0,09560043 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01140371 0,09526848 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01140371 0,09493883 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01140371 0,09461146 ! histidine catabolic process GO:0006548 6 5 0,000 0,01140371 0,09428633 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01140371 0,09396343 ! microvillus organization GO:0032528 7 5 0,000 0,01140371 0,09364274 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01140371 0,09332423 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01140371 0,09300787 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01140371 0,09269366 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01140371 0,09238156 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01140371 0,09207155 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01140371 0,09176362 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01140371 0,09145774 ! polyol catabolic process GO:0046174 7 5 0,000 0,01140371 0,0911539 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01140371 0,09085206 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01140371 0,09055222 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01140371 0,09025435 ! muscle cell migration GO:0014812 8 5 0,000 0,01140371 0,08995843 ! mitochondrial fission GO:0000266 8 5 0,000 0,01140371 0,08966445 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01140371 0,08937239 ! mRNA transcription GO:0009299 9 5 0,000 0,01140371 0,08908222 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01140371 0,08879392 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01140371 0,08850749 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01140371 0,0882229 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01140371 0,08794014 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01140371 0,08765918 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01140371 0,08738001 ! response to food GO:0032094 6 5 0,000 0,01140371 0,08710261 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01140371 0,08682697 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01140371 0,08655307 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01140371 0,08628089 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01140371 0,08601042 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01140371 0,08574163 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01140371 0,08547452 ! forebrain neuron development GO:0021884 13 5 0,000 0,01140371 0,08520908 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01140371 0,08494527 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01140371 0,08468309 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01140371 0,08442253 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01140371 0,08416357 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01140371 0,08390618 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01140371 0,08365037 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01140371 0,08339612 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01140371 0,0831434 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01140371 0,08289221 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01140371 0,08264254 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01140371 0,08239436 ! basic amino acid transport GO:0015802 11 5 0,000 0,01140371 0,08214767 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01140371 0,08190246 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01140371 0,0816587 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01140371 0,08141639 ! depyrimidination GO:0045008 10 5 0,000 0,01140371 0,08117551 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01140371 0,08093605 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01140371 0,08069801 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01140371 0,08046136 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01140371 0,08022609 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01140371 0,07999219 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01140371 0,07975966 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01140371 0,07952847 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01140371 0,07929862 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01140371 0,07907009 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01140371 0,07884288 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01140371 0,07861697 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01140371 0,07839235 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01140371 0,07816901 ! response to arsenic GO:0046685 10 5 0,000 0,01140371 0,07794694 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01140371 0,07772613 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01140371 0,07750656 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01140371 0,07728823 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01140371 0,07707113 ! response to cadmium ion GO:0046686 7 5 0,000 0,01140371 0,07685525 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01140371 0,07664057 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01140371 0,07642708 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01140371 0,07621478 ! decidualization GO:0046697 11 5 0,000 0,01140371 0,07600366 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01140371 0,07579371 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01140371 0,07558491 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01140371 0,07537726 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01140371 0,07517075 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01140371 0,07496536 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01140371 0,0747611 ! neural tube patterning GO:0021532 7 5 0,000 0,01140371 0,07455794 ! embryonic cleavage GO:0040016 6 5 0,000 0,01140371 0,07435589 ! peroxisome fission GO:0016559 5 5 0,000 0,01140371 0,07415493 ! histone demethylation GO:0016577 10 5 0,000 0,01140371 0,07395505 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01140371 0,07375624 ! mitotic recombination GO:0006312 9 5 0,000 0,01140371 0,07355851 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01140371 0,07336182 ! metaphase plate congression GO:0051310 7 5 0,000 0,01140371 0,07316619 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01140371 0,0729716 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01140371 0,07277804 ! enteric nervous system development GO:0048484 8 5 0,000 0,01140371 0,07258551 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01140371 0,07239399 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01140371 0,07220348 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01140371 0,07201397 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01140371 0,07182545 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01140371 0,07163792 ! plasminogen activation GO:0031639 5 5 0,000 0,01140371 0,07145136 ! B cell homeostasis GO:0001782 13 5 0,000 0,01140371 0,07126577 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01140371 0,07108115 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01140371 0,07089747 ! metaphase GO:0051323 8 5 0,000 0,01140371 0,07071475 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01140371 0,07053296 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01140371 0,07035211 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01140371 0,07017218 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01140371 0,06999317 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01140371 0,06981507 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01140371 0,06963787 ! response to redox state GO:0051775 5 5 0,000 0,01140371 0,06946158 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01140371 0,06928617 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01140371 0,06911164 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01140371 0,068938 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01140371 0,06876522 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01140371 0,06859331 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01140371 0,06842225 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01140371 0,06825205 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01140371 0,06808269 ! striatum development GO:0021756 9 5 0,000 0,01140371 0,06791416 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01140371 0,06774648 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01140371 0,06757961 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01140371 0,06741357 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01140371 0,06724834 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01140371 0,06708392 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01140371 0,0669203 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01140371 0,06675748 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01140371 0,06659544 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01140371 0,06643419 ! neuroprotection GO:0043526 6 5 0,000 0,01140371 0,06627373 ! neural plate development GO:0001840 8 5 0,000 0,01140371 0,06611403 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01140371 0,0659551 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01140371 0,06579694 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01140371 0,06563953 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01140371 0,06548287 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01140371 0,06532696 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01140371 0,06517179 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01140371 0,06501735 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01140371 0,06486365 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01140371 0,06471067 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01140371 0,06455841 ! spindle assembly GO:0051225 6 5 0,000 0,01140371 0,06440686 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01140371 0,06425602 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01140371 0,06410589 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01140371 0,06395646 ! drug metabolic process GO:0017144 6 5 0,000 0,01140371 0,06380773 ! phospholipid scrambling GO:0017121 8 5 0,000 0,01140371 0,06365968 ! organ regeneration GO:0031100 7 5 0,000 0,01140371 0,06351232 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01140371 0,06336564 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01140371 0,06321964 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01140371 0,0630743 ! appendage development GO:0048736 136 71 1,000 0,01161027 0,06406949 GO:0060173|limb development, ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01192447 0,06565283 ! respiratory system development GO:0060541 153 72 1,000 0,01192447 0,06550294 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01256402 0,06885884 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 143 74 1,000 0,01256402 0,06870234 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01288932 0,07032132 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01366902 0,07440649 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01366902 0,07423853 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01366902 0,07407133 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01366902 0,07390487 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01366902 0,07373917 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01366902 0,0735742 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01366902 0,07340997 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01366902 0,07324648 ! sleep GO:0030431 13 6 0,000 0,01366902 0,07308371 ! response to oxygen radical GO:0000305 11 6 0,000 0,01366902 0,07292166 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01366902 0,07276033 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01366902 0,07259971 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01366902 0,0724398 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01366902 0,07228059 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01366902 0,07212208 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01366902 0,07196426 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01366902 0,07180714 ! forebrain regionalization GO:0021871 8 6 0,000 0,01366902 0,07165069 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01366902 0,07149493 ! male meiosis GO:0007140 7 6 0,000 0,01366902 0,07133985 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01366902 0,07118543 ! response to zinc ion GO:0010043 9 6 0,000 0,01366902 0,07103168 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01366902 0,0708786 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01366902 0,07072617 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01366902 0,0705744 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01366902 0,07042327 ! malate metabolic process GO:0006108 11 6 0,000 0,01366902 0,0702728 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01366902 0,07012296 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01366902 0,06997376 ! protein refolding GO:0042026 15 6 0,000 0,01366902 0,0698252 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01366902 0,06967726 ! opsonization GO:0008228 8 6 0,000 0,01366902 0,06952995 ! mating behavior GO:0007617 7 6 0,000 0,01366902 0,06938327 ! neuron remodeling GO:0016322 15 6 0,000 0,01366902 0,0692372 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01366902 0,06909174 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01366902 0,06894689 ! equilibrioception GO:0050957 14 6 0,000 0,01366902 0,06880265 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01366902 0,06865902 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01366902 0,06851598 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01366902 0,06837353 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01366902 0,06823168 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01366902 0,06809041 ! toxin metabolic process GO:0009404 11 6 0,000 0,01366902 0,06794973 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01366902 0,06780963 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01366902 0,0676701 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01366902 0,06753115 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01366902 0,06739276 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01366902 0,06725495 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01366902 0,06711769 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01366902 0,066981 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01366902 0,06684486 ! thymic T cell selection GO:0045061 12 6 0,000 0,01366902 0,06670927 ! protein lipoylation GO:0009249 10 6 0,000 0,01366902 0,06657423 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01366902 0,06643973 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01366902 0,06630578 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01366902 0,06617237 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01366902 0,0660395 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01366902 0,06590715 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01366902 0,06577534 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01366902 0,06564405 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01366902 0,06551328 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01366902 0,06538304 ! hyperosmotic response GO:0006972 9 6 0,000 0,01366902 0,06525331 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01366902 0,0651241 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01366902 0,06499539 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01366902 0,0648672 ! urea metabolic process GO:0019627 7 6 0,000 0,01366902 0,06473951 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01366902 0,06461232 ! neutrophil activation GO:0042119 8 6 0,000 0,01366902 0,06448562 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01366902 0,06435943 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01366902 0,06423373 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01366902 0,06410852 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01366902 0,06398379 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01366902 0,06385955 ! neuron apoptosis GO:0051402 9 6 0,000 0,01366902 0,06373579 ! nucleoside salvage GO:0043174 9 6 0,000 0,01366902 0,06361251 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01366902 0,06348971 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01366902 0,06336738 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01366902 0,06324552 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01366902 0,06312412 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01366902 0,0630032 ! carnitine transport GO:0015879 10 6 0,000 0,01366902 0,06288273 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01366902 0,06276273 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01366902 0,06264318 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01366902 0,06252408 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01366902 0,06240544 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01366902 0,06228725 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01366902 0,06216951 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01366902 0,06205221 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01366902 0,06193535 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01366902 0,06181893 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01366902 0,06170294 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01366902 0,06158739 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01366902 0,06147228 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01366902 0,06135759 ! neural nucleus development GO:0048857 14 6 0,000 0,01366902 0,06124333 ! response to UV-C GO:0010225 11 6 0,000 0,01366902 0,0611295 ! astrocyte development GO:0014002 15 6 0,000 0,01366902 0,06101608 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01366902 0,06090309 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01366902 0,06079052 ! interaction with symbiont GO:0051702 13 6 0,000 0,01366902 0,06067836 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01366902 0,06056661 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01366902 0,06045527 ! response to copper ion GO:0046688 10 6 0,000 0,01366902 0,06034435 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01366902 0,06023383 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01366902 0,06012371 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01366902 0,06001399 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01366902 0,05990468 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01366902 0,05979576 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01366902 0,05968724 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01366902 0,05957911 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01366902 0,05947137 ! hair follicle maturation GO:0048820 7 6 0,000 0,01366902 0,05936402 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01366902 0,05925706 ! Schwann cell development GO:0014044 15 6 0,000 0,01366902 0,05915048 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01366902 0,05904429 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01366902 0,05893847 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01366902 0,05883304 ! subpallium development GO:0021544 10 6 0,000 0,01366902 0,05872798 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01366902 0,0586233 ! histone ubiquitination GO:0016574 8 6 0,000 0,01366902 0,05851898 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01366902 0,05841504 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01366902 0,05831147 ! G2 phase GO:0051319 16 6 0,000 0,01366902 0,05820826 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01366902 0,05810542 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01366902 0,05800294 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01366902 0,05790083 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01366902 0,05779907 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01366902 0,05769766 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01366902 0,05759662 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01366902 0,05749592 ! receptor internalization GO:0031623 10 6 0,000 0,01366902 0,05739558 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01366902 0,05729559 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01366902 0,05719595 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01366902 0,05709665 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,01366902 0,05699769 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01366902 0,05689908 ! protein destabilization GO:0031648 9 6 0,000 0,01366902 0,05680081 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01366902 0,05670288 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01366902 0,05660528 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01366902 0,05650802 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01366902 0,0564111 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01366902 0,0563145 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01366902 0,05621824 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01366902 0,0561223 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01366902 0,05602669 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01366902 0,05593141 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01366902 0,05583645 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01366902 0,05574181 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01366902 0,05564749 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01366902 0,05555349 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01366902 0,05545981 ! catecholamine transport GO:0051937 9 6 0,000 0,01366902 0,05536645 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01366902 0,05527339 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01366902 0,05518065 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01366902 0,05508822 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01366902 0,0549961 ! maternal placenta development GO:0001893 12 6 0,000 0,01366902 0,05490429 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01366902 0,05481278 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01366902 0,05472158 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01366902 0,05463068 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01366902 0,05454008 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01366902 0,05444978 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01366902 0,05435978 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01366902 0,05427008 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,01388711 0,05504512 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,01388711 0,05495458 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,01422694 0,05620694 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,01457037 0,05746935 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,01491736 0,05874169 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01526791 0,06002385 ! tRNA transcription GO:0009304 14 7 0,000 0,01592922 0,06252154 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01592922 0,06241972 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01592922 0,06231822 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01592922 0,06221706 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01592922 0,06211622 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01592922 0,06201571 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01592922 0,06191552 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01592922 0,06181566 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01592922 0,06171611 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01592922 0,06161689 ! prostate gland development GO:0030850 13 7 0,000 0,01592922 0,06151799 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01592922 0,0614194 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01592922 0,06132113 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01592922 0,06122317 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01592922 0,06112553 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01592922 0,06102819 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01592922 0,06093117 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01592922 0,06083445 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01592922 0,06073804 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01592922 0,06064194 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01592922 0,06054614 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01592922 0,06045064 ! glycolipid transport GO:0046836 10 7 0,000 0,01592922 0,06035544 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01592922 0,06026054 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01592922 0,06016594 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01592922 0,06007164 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01592922 0,05997763 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01592922 0,05988392 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01592922 0,05979049 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01592922 0,05969736 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01592922 0,05960452 ! mRNA stabilization GO:0048255 18 7 0,000 0,01592922 0,05951197 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01592922 0,0594197 ! fibril organization GO:0043206 16 7 0,000 0,01592922 0,05932772 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01592922 0,05923602 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01592922 0,05914461 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01592922 0,05905348 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01592922 0,05896263 ! lipoprotein transport GO:0042953 14 7 0,000 0,01592922 0,05887205 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01592922 0,05878176 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01592922 0,05869174 ! rhythmic behavior GO:0007622 15 7 0,000 0,01592922 0,058602 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01592922 0,05851253 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01592922 0,05842333 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01592922 0,05833441 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01592922 0,05824575 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01592922 0,05815737 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01592922 0,05806925 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01592922 0,0579814 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01592922 0,05789382 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01592922 0,0578065 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01592922 0,05771944 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01592922 0,05763264 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01592922 0,05754611 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01592922 0,05745983 ! spinal cord patterning GO:0021511 13 7 0,000 0,01592922 0,05737381 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01592922 0,05728805 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01592922 0,05720255 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01592922 0,0571173 ! adrenal gland development GO:0030325 17 7 0,000 0,01592922 0,0570323 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01592922 0,05694756 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01592922 0,05686307 ! ovulation GO:0030728 9 7 0,000 0,01592922 0,05677882 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01592922 0,05669483 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01592922 0,05661109 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01592922 0,05652759 ! microtubule nucleation GO:0007020 20 7 0,000 0,01592922 0,05644434 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01592922 0,05636133 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01592922 0,05627857 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01592922 0,05619605 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01592922 0,05611377 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01592922 0,05603173 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01592922 0,05594994 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01592922 0,05586838 ! galactose metabolic process GO:0006012 13 7 0,000 0,01592922 0,05578705 ! vesicle fusion GO:0006906 17 7 0,000 0,01592922 0,05570597 ! response to dietary excess GO:0002021 8 7 0,000 0,01592922 0,05562512 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01592922 0,0555445 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01592922 0,05546412 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01592922 0,05538397 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01592922 0,05530405 ! organ growth GO:0035265 15 7 0,000 0,01592922 0,05522436 ! purine salvage GO:0043101 10 7 0,000 0,01592922 0,0551449 ! nucleoside transport GO:0015858 8 7 0,000 0,01592922 0,05506567 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01592922 0,05498667 ! parturition GO:0007567 14 7 0,000 0,01592922 0,05490789 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01592922 0,05482934 ! rRNA modification GO:0000154 14 7 0,000 0,01592922 0,05475101 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01592922 0,0546729 ! spindle checkpoint GO:0031577 15 7 0,000 0,01592922 0,05459502 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01592922 0,05451736 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01592922 0,05443992 ! macrophage differentiation GO:0030225 11 7 0,000 0,01592922 0,0543627 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01592922 0,0542857 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01592922 0,05420892 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01592922 0,05413235 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01592922 0,054056 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01592922 0,05397987 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01592922 0,05390395 ! fibrinolysis GO:0042730 10 7 0,000 0,01592922 0,05382824 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01592922 0,05375274 ! eating behavior GO:0042755 7 7 0,000 0,01592922 0,05367746 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01592922 0,05360239 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01592922 0,05352752 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01592922 0,05345287 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01592922 0,05337842 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01592922 0,05330418 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01592922 0,05323015 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01592922 0,05315632 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01592922 0,0530827 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01592922 0,05300928 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01592922 0,05293606 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01592922 0,05286304 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01592922 0,05279023 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01592922 0,05271762 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01592922 0,0526452 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01592922 0,05257299 ! regulation of meiosis GO:0040020 12 7 0,000 0,01592922 0,05250097 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01592922 0,05242915 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01592922 0,05235752 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01592922 0,05228609 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01592922 0,05221486 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01592922 0,05214382 ! transcription termination GO:0006353 13 7 0,000 0,01592922 0,05207297 ! response to tumor cell GO:0002347 13 7 0,000 0,01592922 0,05200232 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01592922 0,05193185 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01592922 0,05186158 ! anaphase GO:0051322 17 7 0,000 0,01592922 0,05179149 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01592922 0,0517216 ! axonal fasciculation GO:0007413 18 7 0,000 0,01592922 0,0516519 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01592922 0,05158238 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01592922 0,05151305 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01592922 0,0514439 ! diuresis GO:0030146 12 7 0,000 0,01592922 0,05137494 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01592922 0,05130617 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01592922 0,05123758 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01592922 0,05116917 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01592922 0,05110094 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01592922 0,0510329 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01592922 0,05096503 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01592922 0,05089735 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01592922 0,05082985 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01592922 0,05076252 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01592922 0,05069538 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01592922 0,05062841 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01592922 0,05056162 ! lymph node development GO:0048535 10 7 0,000 0,01592922 0,050495 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01592922 0,05042856 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01592922 0,05036229 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01592922 0,0502962 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01592922 0,05023028 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01592922 0,05016454 ! adult feeding behavior GO:0008343 9 7 0,000 0,01592922 0,05009896 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01592922 0,05003356 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01592922 0,04996833 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01592922 0,04990326 ! muscle adaptation GO:0043500 14 7 0,000 0,01592922 0,04983837 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01592922 0,04977364 ! retina homeostasis GO:0001895 12 7 0,000 0,01592922 0,04970909 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01592922 0,0496447 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01592922 0,04958047 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01592922 0,04951642 ! protein prenylation GO:0018342 18 7 0,000 0,01592922 0,04945252 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01592922 0,0493888 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01592922 0,04932523 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01592922 0,04926183 ! negative regulation of growth GO:0045926 155 84 1,000 0,0159796 0,0493542 ! amine biosynthetic process GO:0009309 138 86 1,000 0,01670529 0,0515294 ! regulation of protein transport GO:0051223 154 87 1,000 0,01707335 0,05259728 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,01744485 0,05367303 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,01781979 0,05475659 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01818432 0,05580544 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01818432 0,05573435 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01818432 0,05566344 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01818432 0,05559271 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01818432 0,05552216 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01818432 0,05545179 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01818432 0,0553816 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01818432 0,05531158 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01818432 0,05524175 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01818432 0,05517208 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01818432 0,0551026 ! meiotic prophase I GO:0007128 13 8 0,000 0,01818432 0,05503329 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01818432 0,05496415 ! oligopeptide transport GO:0006857 15 8 0,000 0,01818432 0,05489519 ! UTP metabolic process GO:0046051 8 8 0,000 0,01818432 0,05482639 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01818432 0,05475778 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01818432 0,05468933 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01818432 0,05462105 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01818432 0,05455295 ! succinate metabolic process GO:0006105 14 8 0,000 0,01818432 0,05448501 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01818432 0,05441724 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01818432 0,05434964 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01818432 0,05428221 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01818432 0,05421495 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01818432 0,05414785 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01818432 0,05408092 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01818432 0,05401415 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01818432 0,05394755 ! reflex GO:0060004 16 8 0,000 0,01818432 0,05388111 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01818432 0,05381484 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01818432 0,05374873 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01818432 0,05368278 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01818432 0,05361699 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01818432 0,05355136 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01818432 0,0534859 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01818432 0,05342059 ! pigment granule organization GO:0048753 16 8 0,000 0,01818432 0,05335544 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01818432 0,05329045 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01818432 0,05322562 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01818432 0,05316095 ! histidine metabolic process GO:0006547 16 8 0,000 0,01818432 0,05309644 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01818432 0,05303208 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01818432 0,05296787 ! glycine catabolic process GO:0006546 13 8 0,000 0,01818432 0,05290382 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01818432 0,05283993 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01818432 0,05277619 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01818432 0,05271261 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01818432 0,05264917 ! melanin metabolic process GO:0006582 15 8 0,000 0,01818432 0,05258589 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01818432 0,05252276 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01818432 0,05245979 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01818432 0,05239696 ! macrophage activation GO:0042116 12 8 0,000 0,01818432 0,05233429 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01818432 0,05227176 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01818432 0,05220938 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01818432 0,05214715 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01818432 0,05208507 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01818432 0,05202314 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01818432 0,05196136 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01818432 0,05189972 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01818432 0,05183823 ! osteoblast development GO:0002076 16 8 0,000 0,01818432 0,05177688 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01818432 0,05171568 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01818432 0,05165462 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01818432 0,05159371 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01818432 0,05153294 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01818432 0,05147231 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01818432 0,05141182 ! response to UV-B GO:0010224 16 8 0,000 0,01818432 0,05135148 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01818432 0,05129128 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01818432 0,05123122 ! intermediate filament organization GO:0045109 12 8 0,000 0,01818432 0,0511713 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01818432 0,05111152 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01818432 0,05105188 ! cellular extravasation GO:0045123 12 8 0,000 0,01818432 0,05099238 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01818432 0,05093302 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01818432 0,05087379 ! response to antibiotic GO:0046677 11 8 0,000 0,01818432 0,05081471 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01818432 0,05075576 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01818432 0,05069694 ! DNA topological change GO:0006265 12 8 0,000 0,01818432 0,05063827 ! response to tropane GO:0014073 15 8 0,000 0,01818432 0,05057973 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01818432 0,05052132 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01818432 0,05046305 ! melanosome transport GO:0032402 13 8 0,000 0,01818432 0,05040491 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01818432 0,05034691 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01818432 0,05028904 ! mast cell activation GO:0045576 14 8 0,000 0,01818432 0,0502313 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01818432 0,0501737 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01818432 0,05011622 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01818432 0,05005888 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01818432 0,05000167 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01818432 0,04994459 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01818432 0,04988764 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01818432 0,04983082 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01818432 0,04977413 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01818432 0,04971757 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01818432 0,04966114 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01818432 0,04960483 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01818432 0,04954866 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01818432 0,0494926 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01818432 0,04943668 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01818432 0,04938088 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01818432 0,04932521 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01818432 0,04926967 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01818432 0,04921424 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01818432 0,04915895 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01818432 0,04910377 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01818432 0,04904873 ! ATP catabolic process GO:0006200 11 8 0,000 0,01818432 0,0489938 ! blastocyst growth GO:0001832 19 8 0,000 0,01818432 0,048939 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01818432 0,04888432 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01818432 0,04882976 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01818432 0,04877532 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01818432 0,04872101 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01818432 0,04866681 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01818432 0,04861274 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01818432 0,04855878 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01818432 0,04850495 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01818432 0,04845123 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01818432 0,04839764 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01818432 0,04834416 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01818432 0,0482908 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01818432 0,04823756 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01818432 0,04818443 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01818432 0,04813142 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01818432 0,04807853 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01818432 0,04802575 ! ossification GO:0001503 188 90 1,000 0,01819814 0,04800956 ! bone development GO:0060348 189 91 1,000 0,01857988 0,04896298 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02043432 0,05379099 ! axon extension GO:0048675 15 9 0,000 0,02043432 0,0537322 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02043432 0,05367354 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02043432 0,05361501 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02043432 0,05355661 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02043432 0,05349833 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02043432 0,05344018 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02043432 0,05338216 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02043432 0,05332426 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02043432 0,05326648 ! phosphate transport GO:0006817 19 9 0,000 0,02043432 0,05320884 ! reproductive behavior GO:0019098 19 9 0,000 0,02043432 0,05315131 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02043432 0,05309392 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02043432 0,05303664 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02043432 0,05297949 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02043432 0,05292246 ! GTP metabolic process GO:0046039 9 9 0,000 0,02043432 0,05286555 ! RNA methylation GO:0001510 15 9 0,000 0,02043432 0,05280877 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02043432 0,05275211 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02043432 0,05269557 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02043432 0,05263915 ! artery development GO:0060840 24 9 0,000 0,02043432 0,05258285 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02043432 0,05252667 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02043432 0,05247061 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02043432 0,05241468 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02043432 0,05235886 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02043432 0,05230315 ! chemosensory behavior GO:0007635 20 9 0,000 0,02043432 0,05224757 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02043432 0,05219211 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02043432 0,05213676 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02043432 0,05208153 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02043432 0,05202642 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02043432 0,05197142 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02043432 0,05191654 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02043432 0,05186178 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02043432 0,05180713 ! protein targeting to ER GO:0045047 22 9 0,000 0,02043432 0,0517526 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02043432 0,05169818 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02043432 0,05164387 ! T cell selection GO:0045058 23 9 0,000 0,02043432 0,05158968 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02043432 0,0515356 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02043432 0,05148164 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02043432 0,05142779 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02043432 0,05137405 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02043432 0,05132042 ! mannose metabolic process GO:0006013 13 9 0,000 0,02043432 0,05126691 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02043432 0,05121351 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02043432 0,05116021 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02043432 0,05110703 ! receptor clustering GO:0043113 18 9 0,000 0,02043432 0,05105396 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02043432 0,051001 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02043432 0,05094815 ! ruffle organization GO:0031529 15 9 0,000 0,02043432 0,05089541 ! retinol metabolic process GO:0042572 18 9 0,000 0,02043432 0,05084278 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02043432 0,05079025 ! behavioral fear response GO:0001662 22 9 0,000 0,02043432 0,05073784 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02043432 0,05068553 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02043432 0,05063333 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02043432 0,05058124 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02043432 0,05052926 ! protein heterooligomerization GO:0051291 16 9 0,000 0,02043432 0,05047738 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02043432 0,05042561 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02043432 0,05037394 ! segment specification GO:0007379 13 9 0,000 0,02043432 0,05032238 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02043432 0,05027093 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02043432 0,05021958 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02043432 0,05016833 ! response to amine stimulus GO:0014075 13 9 0,000 0,02043432 0,05011719 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02043432 0,05006616 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02043432 0,05001522 ! erythrocyte development GO:0048821 15 9 0,000 0,02043432 0,0499644 ! gas homeostasis GO:0033483 16 9 0,000 0,02043432 0,04991367 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02043432 0,04986305 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02043432 0,04981253 ! renal water homeostasis GO:0003091 14 9 0,000 0,02043432 0,04976211 ! postreplication repair GO:0006301 22 9 0,000 0,02043432 0,0497118 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02043432 0,04966158 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02043432 0,04961147 ! icosanoid secretion GO:0032309 15 9 0,000 0,02043432 0,04956146 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02043432 0,04951155 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02043432 0,04946174 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02043432 0,04941203 ! regulation of cell division GO:0051302 15 9 0,000 0,02043432 0,04936241 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02043432 0,0493129 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02043432 0,04926349 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02043432 0,04921418 ! sterol catabolic process GO:0016127 11 9 0,000 0,02043432 0,04916497 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02043432 0,04911585 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02043432 0,04906683 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02043432 0,04901791 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02043432 0,04896909 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02043432 0,04892036 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02043432 0,04887173 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02043432 0,0488232 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02043432 0,04877477 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02043432 0,04872643 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02043432 0,04867818 ! purine base metabolic process GO:0006144 21 9 0,000 0,02043432 0,04863003 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02043432 0,04858198 ! pigment granule transport GO:0051904 17 9 0,000 0,02043432 0,04853402 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02043432 0,04848616 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02043432 0,04843839 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02043432 0,04839071 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02043432 0,04834313 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02043432 0,04829564 ! mitochondrion localization GO:0051646 15 9 0,000 0,02043432 0,04824825 ! positive regulation of immune response GO:0050778 156 96 1,000 0,02053899 0,04844784 ! hormone metabolic process GO:0042445 157 97 1,000 0,02094076 0,04934718 ! regulation of protein localization GO:0032880 176 97 1,000 0,02094076 0,04929889 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,02175413 0,05116368 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 0,02216569 0,05208072 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02267924 0,05323536 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02267924 0,05318347 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02267924 0,05313169 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02267924 0,05308 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02267924 0,05302842 ! synapsis GO:0007129 13 10 0,000 0,02267924 0,05297693 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02267924 0,05292555 ! N-glycan processing GO:0006491 20 10 0,000 0,02267924 0,05287426 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02267924 0,05282308 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02267924 0,05277199 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02267924 0,05272101 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02267924 0,05267012 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02267924 0,05261933 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02267924 0,05256863 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02267924 0,05251804 ! androgen metabolic process GO:0008209 17 10 0,000 0,02267924 0,05246754 ! phospholipid efflux GO:0033700 16 10 0,000 0,02267924 0,05241714 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02267924 0,05236683 ! lung alveolus development GO:0048286 26 10 0,000 0,02267924 0,05231663 ! pathogenesis GO:0009405 13 10 0,000 0,02267924 0,05226651 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02267924 0,0522165 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02267924 0,05216658 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02267924 0,05211675 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02267924 0,05206702 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02267924 0,05201739 ! endoderm development GO:0007492 16 10 0,000 0,02267924 0,05196785 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02267924 0,0519184 ! arginine catabolic process GO:0006527 13 10 0,000 0,02267924 0,05186905 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02267924 0,05181979 ! proline metabolic process GO:0006560 13 10 0,000 0,02267924 0,05177063 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02267924 0,05172156 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02267924 0,05167258 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02267924 0,05162369 ! V(D)J recombination GO:0033151 28 10 0,000 0,02267924 0,0515749 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02267924 0,0515262 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02267924 0,05147759 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02267924 0,05142907 ! B cell proliferation GO:0042100 18 10 0,000 0,02267924 0,05138064 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02267924 0,05133231 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02267924 0,05128406 ! multicellular organism growth GO:0035264 18 10 0,000 0,02267924 0,05123591 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02267924 0,05118784 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02267924 0,05113987 ! epithelial cell development GO:0002064 20 10 0,000 0,02267924 0,05109199 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02267924 0,05104419 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02267924 0,05099649 ! macroautophagy GO:0016236 17 10 0,000 0,02267924 0,05094887 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02267924 0,05090134 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02267924 0,05085391 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02267924 0,05080656 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02267924 0,05075929 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02267924 0,05071212 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02267924 0,05066503 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02267924 0,05061803 ! brain morphogenesis GO:0048854 23 10 0,000 0,02267924 0,05057112 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02267924 0,0505243 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02267924 0,05047756 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02267924 0,05043091 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02267924 0,05038434 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02267924 0,05033786 ! response to dsRNA GO:0043331 20 10 0,000 0,02267924 0,05029147 ! DNA ligation GO:0006266 19 10 0,000 0,02267924 0,05024516 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02267924 0,05019893 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02267924 0,0501528 ! melanosome localization GO:0032400 16 10 0,000 0,02267924 0,05010674 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02267924 0,05006077 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02267924 0,05001489 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02267924 0,04996909 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02267924 0,04992337 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02267924 0,04987773 ! mRNA cleavage GO:0006379 17 10 0,000 0,02267924 0,04983218 ! protein sumoylation GO:0016925 15 10 0,000 0,02267924 0,04978672 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02267924 0,04974133 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02267924 0,04969603 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02267924 0,04965081 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02267924 0,04960567 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02267924 0,04956062 ! prophase GO:0051324 15 10 0,000 0,02267924 0,04951565 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02267924 0,04947075 ! apical protein localization GO:0045176 15 10 0,000 0,02267924 0,04942594 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02267924 0,04938121 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02267924 0,04933657 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02267924 0,049292 ! midbrain development GO:0030901 13 10 0,000 0,02267924 0,04924751 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02267924 0,0492031 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02267924 0,04915878 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02267924 0,04911453 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02267924 0,04907036 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02267924 0,04902627 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02267924 0,04898226 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02267924 0,04893833 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02267924 0,04889448 ! oocyte development GO:0048599 17 10 0,000 0,02267924 0,04885071 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02267924 0,04880701 ! blastocyst formation GO:0001825 17 10 0,000 0,02267924 0,0487634 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02267924 0,04871986 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02267924 0,0486764 ! activation of innate immune response GO:0002218 12 10 0,000 0,02267924 0,04863301 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02267924 0,04858971 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02267924 0,04854648 ! response to nicotine GO:0035094 20 10 0,000 0,02267924 0,04850333 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02267924 0,04846025 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02267924 0,04841725 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02267924 0,04837433 ! localization within membrane GO:0051668 20 10 0,000 0,02267924 0,04833148 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02491908 0,0530578 ! respiratory burst GO:0045730 17 11 0,000 0,02491908 0,05301089 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02491908 0,05296406 ! neuron fate specification GO:0048665 17 11 0,000 0,02491908 0,05291731 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02491908 0,05287065 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02491908 0,05282407 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02491908 0,05277757 ! thyroid gland development GO:0030878 26 11 0,000 0,02491908 0,05273115 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02491908 0,05268481 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02491908 0,05263856 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02491908 0,05259238 ! response to pain GO:0048265 24 11 0,000 0,02491908 0,05254629 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02491908 0,05250028 ! T cell proliferation GO:0042098 26 11 0,000 0,02491908 0,05245435 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02491908 0,05240849 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02491908 0,05236272 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02491908 0,05231703 ! bone resorption GO:0045453 16 11 0,000 0,02491908 0,05227142 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02491908 0,05222589 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02491908 0,05218043 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02491908 0,05213506 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02491908 0,05208976 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02491908 0,05204455 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02491908 0,05199941 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02491908 0,05195435 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02491908 0,05190937 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02491908 0,05186446 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02491908 0,05181964 ! lipid digestion GO:0044241 18 11 0,000 0,02491908 0,05177489 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02491908 0,05173021 ! UV protection GO:0009650 19 11 0,000 0,02491908 0,05168562 ! adult heart development GO:0007512 14 11 0,000 0,02491908 0,0516411 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02491908 0,05159666 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02491908 0,05155229 ! temperature homeostasis GO:0001659 17 11 0,000 0,02491908 0,05150801 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02491908 0,05146379 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02491908 0,05141966 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02491908 0,05137559 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02491908 0,05133161 ! regulation of organ growth GO:0046620 13 11 0,000 0,02491908 0,0512877 ! pigment granule localization GO:0051875 20 11 0,000 0,02491908 0,05124386 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02491908 0,0512001 ! vasoconstriction GO:0042310 18 11 0,000 0,02491908 0,05115641 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02491908 0,0511128 ! embryonic axis specification GO:0000578 18 11 0,000 0,02491908 0,05106927 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02491908 0,0510258 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02491908 0,05098241 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02491908 0,0509391 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02491908 0,05089586 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02491908 0,05085269 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02491908 0,05080959 ! zymogen activation GO:0031638 15 11 0,000 0,02491908 0,05076657 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02491908 0,05072362 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02491908 0,05068074 ! nucleosome positioning GO:0016584 15 11 0,000 0,02491908 0,05063794 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02491908 0,0505952 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02491908 0,05055254 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02491908 0,05050996 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02491908 0,05046744 ! acid secretion GO:0046717 18 11 0,000 0,02491908 0,05042499 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02491908 0,05038262 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02491908 0,05034032 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02491908 0,05029809 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02491908 0,05025592 ! oocyte differentiation GO:0009994 18 11 0,000 0,02491908 0,05021383 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02491908 0,05017181 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02491908 0,05012986 ! cholesterol efflux GO:0033344 19 11 0,000 0,02491908 0,05008798 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02491908 0,05004618 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02491908 0,05000444 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02491908 0,04996276 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02491908 0,04992116 ! embryonic gut development GO:0048566 15 11 0,000 0,02491908 0,04987963 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02491908 0,04983817 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02491908 0,04979678 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02491908 0,04975545 ! defense response to fungus GO:0050832 13 11 0,000 0,02491908 0,04971419 ! developmental induction GO:0031128 19 11 0,000 0,02491908 0,04967301 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02491908 0,04963189 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02491908 0,04959083 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02491908 0,04954985 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02491908 0,04950893 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02491908 0,04946808 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02491908 0,0494273 ! nucleus localization GO:0051647 19 11 0,000 0,02491908 0,04938659 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02491908 0,04934594 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02715387 0,05372716 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02715387 0,05368301 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02715387 0,05363893 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02715387 0,05359493 ! virus-host interaction GO:0019048 29 12 0,000 0,02715387 0,053551 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02715387 0,05350714 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02715387 0,05346336 ! cartilage condensation GO:0001502 20 12 0,000 0,02715387 0,05341964 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02715387 0,053376 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02715387 0,05333243 ! protein complex disassembly GO:0043241 27 12 0,000 0,02715387 0,05328893 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02715387 0,05324549 ! hippocampus development GO:0021766 26 12 0,000 0,02715387 0,05320214 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02715387 0,05315885 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02715387 0,05311563 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02715387 0,05307248 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02715387 0,0530294 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02715387 0,05298639 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02715387 0,05294345 ! drug transport GO:0015893 16 12 0,000 0,02715387 0,05290058 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02715387 0,05285779 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02715387 0,05281505 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02715387 0,05277239 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02715387 0,0527298 ! focal adhesion formation GO:0048041 35 12 0,000 0,02715387 0,05268728 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02715387 0,05264482 ! forebrain cell migration GO:0021885 21 12 0,000 0,02715387 0,05260243 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02715387 0,05256011 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02715387 0,05251786 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02715387 0,05247568 ! entry into host cell GO:0030260 32 12 0,000 0,02715387 0,05243357 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02715387 0,05239152 ! monoamine transport GO:0015844 18 12 0,000 0,02715387 0,05234954 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02715387 0,05230762 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02715387 0,05226578 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02715387 0,052224 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02715387 0,05218229 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02715387 0,05214064 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02715387 0,05209906 ! protein homotetramerization GO:0051289 21 12 0,000 0,02715387 0,05205755 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02715387 0,0520161 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02715387 0,05197472 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02715387 0,0519334 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02715387 0,05189215 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02715387 0,05185097 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02715387 0,05180985 ! cranial nerve development GO:0021545 20 12 0,000 0,02715387 0,0517688 ! fucose catabolic process GO:0019317 22 12 0,000 0,02715387 0,05172781 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02715387 0,05168688 ! histone methylation GO:0016571 26 12 0,000 0,02715387 0,05164603 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02715387 0,05160523 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02715387 0,0515645 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02715387 0,05152383 ! T cell homeostasis GO:0043029 25 12 0,000 0,02715387 0,05148323 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02715387 0,05144269 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02715387 0,05140222 ! spleen development GO:0048536 22 12 0,000 0,02715387 0,05136181 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02715387 0,05132146 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02715387 0,05128118 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02715387 0,05124096 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02715387 0,0512008 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02715387 0,05116071 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02715387 0,05112067 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02715387 0,05108071 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02715387 0,0510408 ! response to cold GO:0009409 17 12 0,000 0,02715387 0,05100095 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02715387 0,05096117 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02715387 0,05092145 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02938362 0,05505995 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02938362 0,05501711 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02938362 0,05497432 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02938362 0,05493161 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02938362 0,05488896 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02938362 0,05484638 ! lipid localization GO:0010876 28 13 0,000 0,02938362 0,05480386 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02938362 0,05476141 ! organelle fusion GO:0048284 32 13 0,000 0,02938362 0,05471903 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02938362 0,05467671 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02938362 0,05463445 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02938362 0,05459226 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02938362 0,05455014 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02938362 0,05450808 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02938362 0,05446609 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02938362 0,05442416 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02938362 0,05438229 ! methionine metabolic process GO:0006555 27 13 0,000 0,02938362 0,05434049 ! plasma membrane organization GO:0007009 24 13 0,000 0,02938362 0,05429876 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02938362 0,05425708 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02938362 0,05421548 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02938362 0,05417393 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02938362 0,05413245 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02938362 0,05409103 ! response to X-ray GO:0010165 25 13 0,000 0,02938362 0,05404968 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02938362 0,05400839 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02938362 0,05396716 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02938362 0,053926 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02938362 0,05388489 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02938362 0,05384385 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02938362 0,05380288 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02938362 0,05376196 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02938362 0,05372111 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02938362 0,05368032 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02938362 0,05363959 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02938362 0,05359892 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02938362 0,05355832 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02938362 0,05351778 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02938362 0,05347729 ! ribosome assembly GO:0042255 17 13 0,000 0,02938362 0,05343687 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02938362 0,05339651 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02938362 0,05335621 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02938362 0,05331597 ! chromatin silencing GO:0006342 26 13 0,000 0,02938362 0,0532758 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02938362 0,05323568 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02938362 0,05319562 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02938362 0,05315563 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02938362 0,05311569 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02938362 0,05307581 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02938362 0,053036 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02938362 0,05299624 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02938362 0,05295654 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02938362 0,0529169 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02938362 0,05287732 ! embryonic placenta development GO:0001892 23 13 0,000 0,02938362 0,0528378 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02938362 0,05279834 ! insulin secretion GO:0030073 23 13 0,000 0,02938362 0,05275894 ! actin filament polymerization GO:0030041 24 13 0,000 0,02938362 0,0527196 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02938362 0,05268031 ! acrosome reaction GO:0007340 18 13 0,000 0,02938362 0,05264109 ! rRNA transcription GO:0009303 25 14 0,000 0,03160832 0,05658454 ! lactation GO:0007595 26 14 0,000 0,03160832 0,05654247 ! reproductive cellular process GO:0048610 20 14 0,000 0,03160832 0,05650046 ! tRNA modification GO:0006400 20 14 0,000 0,03160832 0,05645852 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03160832 0,05641663 ! regulation of S phase GO:0033261 23 14 0,000 0,03160832 0,05637481 ! water transport GO:0006833 21 14 0,000 0,03160832 0,05633305 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03160832 0,05629136 ! non-recombinational repair GO:0000726 25 14 0,000 0,03160832 0,05624972 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03160832 0,05620815 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03160832 0,05616663 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03160832 0,05612518 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03160832 0,05608379 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03160832 0,05604246 ! palate development GO:0060021 31 14 0,000 0,03160832 0,05600119 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03160832 0,05595999 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03160832 0,05591884 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03160832 0,05587775 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03160832 0,05583673 ! arginine metabolic process GO:0006525 17 14 0,000 0,03160832 0,05579576 ! regulation of heart rate GO:0002027 24 14 0,000 0,03160832 0,05575486 ! organic alcohol transport GO:0015850 29 14 0,000 0,03160832 0,05571401 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03160832 0,05567322 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03160832 0,0556325 ! embryo implantation GO:0007566 30 14 0,000 0,03160832 0,05559183 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03160832 0,05555122 ! L-amino acid transport GO:0015807 30 14 0,000 0,03160832 0,05551067 ! bone mineralization GO:0030282 17 14 0,000 0,03160832 0,05547018 ! stem cell development GO:0048864 43 14 0,000 0,03160832 0,05542975 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03160832 0,05538938 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03160832 0,05534907 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03160832 0,05530882 ! cerebellum development GO:0021549 21 14 0,000 0,03160832 0,05526862 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03160832 0,05522848 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03160832 0,05518841 ! response to gamma radiation GO:0010332 28 14 0,000 0,03160832 0,05514838 ! cofactor transport GO:0051181 26 14 0,000 0,03160832 0,05510842 ! NADP metabolic process GO:0006739 24 14 0,000 0,03160832 0,05506852 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03160832 0,05502867 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03160832 0,05498888 ! intestinal absorption GO:0050892 25 14 0,000 0,03160832 0,05494915 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03160832 0,05490947 ! oxygen transport GO:0015671 21 14 0,000 0,03160832 0,05486986 ! male genitalia development GO:0030539 24 14 0,000 0,03160832 0,0548303 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03160832 0,05479079 ! regulation of axon extension GO:0030516 37 14 0,000 0,03160832 0,05475135 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03160832 0,05471196 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03160832 0,05467263 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,033828 0,05846995 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,033828 0,05842798 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,033828 0,05838606 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,033828 0,05834421 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,033828 0,05830242 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,033828 0,05826068 ! copper ion transport GO:0006825 20 15 0,000 0,033828 0,05821901 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,033828 0,05817739 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,033828 0,05813584 ! sulfate transport GO:0008272 23 15 0,000 0,033828 0,05809434 ! response to cAMP GO:0051591 22 15 0,000 0,033828 0,0580529 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,033828 0,05801153 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,033828 0,05797021 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,033828 0,05792895 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,033828 0,05788775 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,033828 0,0578466 ! response to hexose stimulus GO:0009746 22 15 0,000 0,033828 0,05780552 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,033828 0,05776449 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,033828 0,05772353 ! pituitary gland development GO:0021983 29 15 0,000 0,033828 0,05768262 ! vesicle coating GO:0006901 33 15 0,000 0,033828 0,05764177 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,033828 0,05760097 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,033828 0,05756024 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,033828 0,05751956 ! regulation of exocytosis GO:0017157 22 15 0,000 0,033828 0,05747894 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,033828 0,05743837 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,033828 0,05739787 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,033828 0,05735742 ! regulation of vasodilation GO:0042312 26 15 0,000 0,033828 0,05731702 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,033828 0,05727669 ! histone deacetylation GO:0016575 20 15 0,000 0,033828 0,05723641 ! mRNA splice site selection GO:0006376 38 15 0,000 0,033828 0,05719619 ! tissue regeneration GO:0042246 26 15 0,000 0,033828 0,05715602 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,033828 0,05711591 ! water homeostasis GO:0030104 27 15 0,000 0,033828 0,05707586 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,033828 0,05703586 ! muscle maintenance GO:0046716 26 15 0,000 0,033828 0,05699592 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,033828 0,05695603 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,033828 0,0569162 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,033828 0,05687643 ! heme biosynthetic process GO:0006783 29 15 0,000 0,033828 0,05683671 ! cell killing GO:0001906 29 15 0,000 0,033828 0,05679705 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,033828 0,05675744 ! detection of bacterium GO:0016045 18 15 0,000 0,033828 0,05671789 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,033828 0,05667839 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,033828 0,05663895 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,033828 0,05659956 ! peptide hormone processing GO:0016486 23 15 0,000 0,033828 0,05656023 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03604267 0,06022129 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03604267 0,0601795 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03604267 0,06013777 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03604267 0,06009609 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03604267 0,06005447 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03604267 0,06001291 ! filopodium assembly GO:0046847 32 16 0,000 0,03604267 0,05997141 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03604267 0,05992996 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03604267 0,05988858 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03604267 0,05984725 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03604267 0,05980597 ! startle response GO:0001964 28 16 0,000 0,03604267 0,05976475 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03604267 0,05972359 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03604267 0,05968249 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03604267 0,05964144 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03604267 0,05960045 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03604267 0,05955952 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03604267 0,05951864 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03604267 0,05947782 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03604267 0,05943705 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03604267 0,05939634 ! response to osmotic stress GO:0006970 25 16 0,000 0,03604267 0,05935569 ! lysosomal transport GO:0007041 26 16 0,000 0,03604267 0,05931509 ! fructose metabolic process GO:0006000 25 16 0,000 0,03604267 0,05927454 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03604267 0,05923406 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,03604267 0,05919362 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03604267 0,05915325 ! axon cargo transport GO:0008088 43 16 0,000 0,03604267 0,05911292 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03604267 0,05907266 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03604267 0,05903244 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,03604267 0,05899228 ! DNA replication initiation GO:0006270 27 16 0,000 0,03604267 0,05895218 ! neuron recognition GO:0008038 35 16 0,000 0,03604267 0,05891213 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03604267 0,05887214 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03604267 0,0588322 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03604267 0,05879231 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03604267 0,05875248 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03604267 0,0587127 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03604267 0,05867298 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03604267 0,05863331 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03604267 0,05859369 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03604267 0,05855412 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03604267 0,05851461 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03604267 0,05847516 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03604267 0,05843575 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,03604267 0,0583964 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03825233 0,0619348 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03825233 0,06189315 ! metencephalon development GO:0022037 30 17 0,000 0,03825233 0,06185155 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03825233 0,06181001 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03825233 0,06176853 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03825233 0,0617271 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03825233 0,06168573 ! signal complex assembly GO:0007172 41 17 0,000 0,03825233 0,06164441 ! endothelial cell migration GO:0043542 28 17 0,000 0,03825233 0,06160315 ! inositol metabolic process GO:0006020 28 17 0,000 0,03825233 0,06156194 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03825233 0,06152079 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03825233 0,0614797 ! glial cell development GO:0021782 27 17 0,000 0,03825233 0,06143866 ! limbic system development GO:0021761 36 17 0,000 0,03825233 0,06139767 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03825233 0,06135674 ! adult walking behavior GO:0007628 33 17 0,000 0,03825233 0,06131586 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03825233 0,06127504 ! heart looping GO:0001947 30 17 0,000 0,03825233 0,06123427 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03825233 0,06119356 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03825233 0,06115289 ! myoblast differentiation GO:0045445 45 17 0,000 0,03825233 0,06111229 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03825233 0,06107174 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03825233 0,06103124 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03825233 0,06099079 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03825233 0,0609504 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03825233 0,06091006 ! glycine metabolic process GO:0006544 28 17 0,000 0,03825233 0,06086978 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,03825233 0,06082955 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03825233 0,06078937 ! NAD metabolic process GO:0019674 29 17 0,000 0,03825233 0,06074925 ! membrane budding GO:0006900 37 17 0,000 0,03825233 0,06070917 ! DNA integration GO:0015074 29 17 0,000 0,03825233 0,06066915 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03825233 0,06062919 ! regulation of protein binding GO:0043393 33 17 0,000 0,03825233 0,06058927 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03825233 0,06054941 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03825233 0,0605096 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03825233 0,06046985 ! genitalia development GO:0048806 30 17 0,000 0,03825233 0,06043014 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03825233 0,06039049 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03825233 0,06035089 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03825233 0,06031134 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03825233 0,06027184 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03825233 0,0602324 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03825233 0,06019301 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03825233 0,06015366 ! gas transport GO:0015669 25 17 0,000 0,03825233 0,06011437 ! organic cation transport GO:0015695 31 17 0,000 0,03825233 0,06007513 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03825233 0,06003595 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03825233 0,05999681 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03825233 0,05995772 ! microspike assembly GO:0030035 36 17 0,000 0,03825233 0,05991869 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03825233 0,05987971 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,040457 0,06328969 ! neuron maturation GO:0042551 42 18 0,000 0,040457 0,06324857 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,040457 0,0632075 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,040457 0,06316648 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,040457 0,06312552 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,040457 0,0630846 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,040457 0,06304375 ! memory GO:0007613 31 18 0,000 0,040457 0,06300294 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,040457 0,06296219 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,040457 0,06292149 ! patterning of blood vessels GO:0001569 39 18 0,000 0,040457 0,06288084 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,040457 0,06284025 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,040457 0,06279971 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,040457 0,06275922 ! glutamine metabolic process GO:0006541 29 18 0,000 0,040457 0,06271878 ! response to retinoic acid GO:0032526 26 18 0,000 0,040457 0,06267839 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,040457 0,06263806 ! response to fungus GO:0009620 21 18 0,000 0,040457 0,06259778 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,040457 0,06255755 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,040457 0,06251737 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,040457 0,06247724 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,040457 0,06243717 ! vitamin transport GO:0051180 27 18 0,000 0,040457 0,06239714 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,040457 0,06235717 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,040457 0,06231725 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,040457 0,06227738 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,040457 0,06223756 ! nerve development GO:0021675 28 18 0,000 0,040457 0,06219779 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,040457 0,06215807 ! protein secretion GO:0009306 39 19 0,000 0,04265669 0,06549585 ! positive regulation of translation GO:0045727 30 19 0,000 0,04265669 0,06545408 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04265669 0,06541236 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04265669 0,0653707 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04265669 0,06532909 ! skin development GO:0043588 36 19 0,000 0,04265669 0,06528753 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04265669 0,06524603 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04265669 0,06520457 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04265669 0,06516317 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04265669 0,06512183 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04265669 0,06508053 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04265669 0,06503929 ! cerebral cortex development GO:0021987 36 19 0,000 0,04265669 0,0649981 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04265669 0,06495696 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04265669 0,06491588 ! heme metabolic process GO:0042168 36 19 0,000 0,04265669 0,06487484 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04265669 0,06483386 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04265669 0,06479293 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04265669 0,06475205 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04265669 0,06471122 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04265669 0,06467045 ! peptide cross-linking GO:0018149 37 19 0,000 0,04265669 0,06462972 ! protein export from nucleus GO:0006611 36 19 0,000 0,04265669 0,06458905 ! heart process GO:0003015 30 19 0,000 0,04265669 0,06454843 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04265669 0,06450786 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,04265669 0,06446734 ! cellular pigmentation GO:0033059 36 19 0,000 0,04265669 0,06442687 ! G1 phase GO:0051318 40 19 0,000 0,04265669 0,06438645 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04265669 0,06434608 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04265669 0,06430576 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04265669 0,0642655 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04265669 0,06422528 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04265669 0,06418511 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04265669 0,064145 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04265669 0,06410493 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04265669 0,06406492 ! cilium assembly GO:0042384 37 19 0,000 0,04265669 0,06402495 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04265669 0,06398504 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04485141 0,0672352 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04485141 0,06719333 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04485141 0,06715152 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04485141 0,06710976 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04485141 0,06706805 ! response to vitamin GO:0033273 31 20 0,000 0,04485141 0,06702639 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04485141 0,06698479 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04485141 0,06694324 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04485141 0,06690173 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04485141 0,06686028 ! response to alkaloid GO:0043279 38 20 0,000 0,04485141 0,06681888 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04485141 0,06677753 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04485141 0,06673624 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04485141 0,06669499 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04485141 0,0666538 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04485141 0,06661265 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04485141 0,06657156 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04485141 0,06653051 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,04485141 0,06648952 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04485141 0,06644858 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04485141 0,06640769 ! body fluid secretion GO:0007589 31 20 0,000 0,04485141 0,06636685 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04485141 0,06632606 ! peptide secretion GO:0002790 35 20 0,000 0,04485141 0,06628532 ! stem cell differentiation GO:0048863 53 20 0,000 0,04485141 0,06624463 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04485141 0,06620398 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04485141 0,06616339 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04485141 0,06612285 ! sensory perception of pain GO:0019233 30 20 0,000 0,04485141 0,06608236 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04485141 0,06604192 ! diencephalon development GO:0021536 34 20 0,000 0,04485141 0,06600153 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04485141 0,06596118 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04485141 0,06592089 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04485141 0,06588064 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04485141 0,06584045 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04485141 0,0658003 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04485141 0,0657602 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04485141 0,06572016 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04485141 0,06568016 ! regulation of glucose import GO:0046324 29 20 0,000 0,04485141 0,0656402 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04485141 0,0656003 ! actin filament-based movement GO:0030048 43 20 0,000 0,04485141 0,06556045 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04485141 0,06552064 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04485141 0,06548088 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04485141 0,06544117 ! negative regulation of translation GO:0017148 29 20 0,000 0,04485141 0,06540151 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04485141 0,0653619 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04485141 0,06532233 ! regulation of cell killing GO:0031341 42 21 0,000 0,04704117 0,06847009 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04704117 0,06842869 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04704117 0,06838735 ! hormone secretion GO:0046879 38 21 0,000 0,04704117 0,06834605 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04704117 0,0683048 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04704117 0,06826361 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04704117 0,06822246 ! axis specification GO:0009798 38 21 0,000 0,04704117 0,06818136 ! ovarian follicle development GO:0001541 35 21 0,000 0,04704117 0,06814031 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04704117 0,06809931 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04704117 0,06805837 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04704117 0,06801746 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04704117 0,06797661 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04704117 0,06793581 ! cell aging GO:0007569 44 21 0,000 0,04704117 0,06789506 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04704117 0,06785435 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04704117 0,0678137 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04704117 0,06777309 ! cytolysis GO:0019835 24 21 0,000 0,04704117 0,06773253 ! vasodilation GO:0042311 39 21 0,000 0,04704117 0,06769202 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04704117 0,06765156 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,04704117 0,06761115 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04704117 0,06757078 ! oogenesis GO:0048477 36 21 0,000 0,04704117 0,06753047 ! DNA modification GO:0006304 34 21 0,000 0,04704117 0,0674902 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04704117 0,06744998 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04704117 0,0674098 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04704117 0,06736968 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04704117 0,0673296 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04704117 0,06728957 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04704117 0,06724959 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04704117 0,06720966 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04704117 0,06716977 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04704117 0,06712993 ! collagen catabolic process GO:0030574 28 21 0,000 0,04704117 0,06709014 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04704117 0,06705039 ! gut development GO:0048565 39 21 0,000 0,04704117 0,06701069 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04922599 0,07008149 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04922599 0,07004005 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04922599 0,06999865 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04922599 0,06995731 ! microtubule-based transport GO:0010970 54 22 0,000 0,04922599 0,06991601 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04922599 0,06987476 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04922599 0,06983356 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04922599 0,06979241 ! regeneration GO:0031099 41 22 0,000 0,04922599 0,06975131 ! keratinization GO:0031424 28 22 0,000 0,04922599 0,06971026 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04922599 0,06966925 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04922599 0,06962829 ! sensory perception of taste GO:0050909 28 22 0,000 0,04922599 0,06958738 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,04922599 0,06954652 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04922599 0,06950571 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04922599 0,06946494 ! vacuolar transport GO:0007034 36 22 0,000 0,04922599 0,06942422 ! lysosome organization GO:0007040 41 22 0,000 0,04922599 0,06938355 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04922599 0,06934293 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04922599 0,06930235 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04922599 0,06926183 ! fucose metabolic process GO:0006004 39 22 0,000 0,04922599 0,06922135 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04922599 0,06918091 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04922599 0,06914053 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04922599 0,06910019 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04922599 0,0690599 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04922599 0,06901965 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04922599 0,06897945 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04922599 0,0689393 ! sarcomere organization GO:0045214 30 22 0,000 0,04922599 0,0688992 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04922599 0,06885914 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04922599 0,06881913 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04922599 0,06877917 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04922599 0,06873925 ! protein stabilization GO:0050821 39 22 0,000 0,04922599 0,06869938 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,05140586 0,0717 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05140586 0,07165846 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05140586 0,07161697 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05140586 0,07157553 ! gluconeogenesis GO:0006094 33 23 0,000 0,05140586 0,07153413 ! viral genome replication GO:0019079 41 23 0,000 0,05140586 0,07149278 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05140586 0,07145148 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05140586 0,07141022 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05140586 0,07136902 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05140586 0,07132786 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05140586 0,07128675 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05140586 0,07124568 ! visual behavior GO:0007632 42 23 0,000 0,05140586 0,07120467 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,05140586 0,0711637 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05140586 0,07112278 ! response to ethanol GO:0045471 46 23 0,000 0,05140586 0,0710819 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05140586 0,07104107 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05140586 0,07100029 ! peroxisome organization GO:0007031 37 23 0,000 0,05140586 0,07095956 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05140586 0,07091887 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05140586 0,07087823 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05140586 0,07083763 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05140586 0,07079709 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,05140586 0,07075658 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,05140586 0,07071613 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05140586 0,07067572 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05140586 0,07063536 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05140586 0,07059504 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05140586 0,07055477 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05140586 0,07051454 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05140586 0,07047436 ! fatty acid transport GO:0015908 44 23 0,000 0,05140586 0,07043423 ! platelet activation GO:0030168 37 23 0,000 0,05140586 0,07039414 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05140586 0,0703541 ! hormone transport GO:0009914 40 23 0,000 0,05140586 0,0703141 ! cell-cell recognition GO:0009988 25 23 0,000 0,05140586 0,07027415 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05140586 0,07023425 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05140586 0,07019439 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,05140586 0,07015457 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05140586 0,0701148 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05140586 0,07007508 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05358082 0,07299855 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05358082 0,07295724 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05358082 0,07291597 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05358082 0,07287476 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05358082 0,07283358 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05358082 0,07279246 ! vesicle docking GO:0048278 47 24 0,000 0,05358082 0,07275138 ! spinal cord development GO:0021510 47 24 0,000 0,05358082 0,07271035 ! vacuole organization GO:0007033 43 24 0,000 0,05358082 0,07266936 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05358082 0,07262842 ! digestive system process GO:0022600 39 24 0,000 0,05358082 0,07258752 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05358082 0,07254668 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05358082 0,07250587 ! regulation of behavior GO:0050795 43 24 0,000 0,05358082 0,07246512 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05358082 0,07242441 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05358082 0,07238374 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05358082 0,07234312 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05358082 0,07230255 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05358082 0,07226202 ! membrane depolarization GO:0051899 39 24 0,000 0,05358082 0,07222154 ! pallium development GO:0021543 49 24 0,000 0,05358082 0,0721811 ! pentose metabolic process GO:0019321 35 24 0,000 0,05358082 0,07214071 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,05358082 0,07210036 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05358082 0,07206006 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05358082 0,0720198 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05358082 0,07197959 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05358082 0,07193942 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05358082 0,0718993 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05358082 0,07185922 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05358082 0,07181919 ! regulation of amine transport GO:0051952 40 24 0,000 0,05358082 0,0717792 ! protein tetramerization GO:0051262 52 24 0,000 0,05358082 0,07173926 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05575085 0,0746032 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05575085 0,07456173 ! myelination GO:0042552 45 25 0,000 0,05575085 0,07452031 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05575085 0,07447893 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05575085 0,0744376 ! phototransduction GO:0007602 33 25 0,000 0,05575085 0,07439631 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05575085 0,07435507 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,05575085 0,07431388 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,05575085 0,07427273 ! sperm motility GO:0030317 31 25 0,000 0,05575085 0,07423163 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,05575085 0,07419057 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05575085 0,07414956 ! receptor metabolic process GO:0043112 46 25 0,000 0,05575085 0,07410859 ! chromosome condensation GO:0030261 45 25 0,000 0,05575085 0,07406767 ! response to starvation GO:0042594 42 25 0,000 0,05575085 0,07402679 ! osteoblast differentiation GO:0001649 60 25 0,000 0,05575085 0,07398596 ! neural crest cell development GO:0014032 54 25 0,000 0,05575085 0,07394518 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05575085 0,07390444 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05575085 0,07386374 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05575085 0,07382309 ! interaction with host GO:0051701 62 25 0,000 0,05575085 0,07378248 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,05575085 0,07374192 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05575085 0,0737014 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,05575085 0,07366093 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05575085 0,0736205 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05575085 0,07358012 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,05575085 0,07353978 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05575085 0,07349948 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05575085 0,07345923 ! telomere organization GO:0032200 43 25 0,000 0,05575085 0,07341902 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05575085 0,07337886 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05575085 0,07333874 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05791599 0,07614528 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05791599 0,07610369 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05791599 0,07606215 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05791599 0,07602066 ! initiation of viral infection GO:0019059 57 26 0,000 0,05791599 0,0759792 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05791599 0,0759378 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05791599 0,07589644 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05791599 0,07585512 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05791599 0,07581385 ! tube lumen formation GO:0035148 50 26 0,000 0,05791599 0,07577263 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05791599 0,07573145 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,05791599 0,07569031 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05791599 0,07564922 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,05791599 0,07560817 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05791599 0,07556717 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05791599 0,07552621 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05791599 0,0754853 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05791599 0,07544443 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05791599 0,0754036 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05791599 0,07536282 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05791599 0,07532209 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05791599 0,07528139 ! blastocyst development GO:0001824 49 26 0,000 0,05791599 0,07524075 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05791599 0,07520014 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05791599 0,07515958 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,06007623 0,07792097 ! neuron fate commitment GO:0048663 48 27 0,000 0,06007623 0,07787899 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06007623 0,07783705 ! iron ion transport GO:0006826 59 27 0,000 0,06007623 0,07779516 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,06007623 0,07775331 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06007623 0,07771151 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06007623 0,07766975 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06007623 0,07762803 ! fat cell differentiation GO:0045444 50 27 0,000 0,06007623 0,07758637 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06007623 0,07754474 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,06007623 0,07750316 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06007623 0,07746163 ! autophagy GO:0006914 41 27 0,000 0,06007623 0,07742014 ! male gonad development GO:0008584 44 27 0,000 0,06007623 0,07737869 ! response to toxin GO:0009636 47 27 0,000 0,06007623 0,07733729 ! primary neural tube formation GO:0014020 51 27 0,000 0,06007623 0,07729594 ! base-excision repair GO:0006284 41 27 0,000 0,06007623 0,07725462 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06007623 0,07721336 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06007623 0,07717213 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06007623 0,07713095 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06007623 0,07708981 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06007623 0,07704872 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06007623 0,07700767 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06007623 0,07696667 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,06007623 0,07692571 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06223158 0,07964319 ! circadian rhythm GO:0007623 50 28 0,000 0,06223158 0,07960085 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06223158 0,07955855 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06223158 0,0795163 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06223158 0,07947409 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06223158 0,07943193 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06223158 0,07938982 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06223158 0,07934774 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06223158 0,07930572 ! synaptogenesis GO:0007416 42 28 0,000 0,06223158 0,07926373 ! lipid oxidation GO:0034440 43 28 0,000 0,06223158 0,0792218 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06223158 0,0791799 ! translational initiation GO:0006413 65 29 0,000 0,06438207 0,08187276 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06438207 0,08182951 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06438207 0,08178631 ! regulation of pH GO:0006885 43 29 0,000 0,06438207 0,08174315 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06438207 0,08170004 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06438207 0,08165697 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06438207 0,08161394 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06438207 0,08157097 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06438207 0,08152803 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06438207 0,08148515 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06438207 0,08144231 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06438207 0,08139951 ! cell fate determination GO:0001709 60 29 0,000 0,06438207 0,08135676 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06438207 0,08131405 ! detection of light stimulus GO:0009583 38 29 0,000 0,06438207 0,08127139 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,06438207 0,08122877 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06438207 0,0811862 ! tissue homeostasis GO:0001894 48 29 0,000 0,06438207 0,08114367 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,06438207 0,08110119 ! zinc ion transport GO:0006829 45 30 0,000 0,0665277 0,08376015 ! membrane docking GO:0022406 61 30 0,000 0,0665277 0,08371634 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0665277 0,08367258 ! cell junction assembly GO:0034329 78 30 0,000 0,0665277 0,08362886 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0665277 0,08358519 ! acute-phase response GO:0006953 49 30 0,000 0,0665277 0,08354157 ! myofibril assembly GO:0030239 47 30 0,000 0,0665277 0,08349799 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,0665277 0,08345446 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0665277 0,08341097 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0665277 0,08336752 ! phospholipid transport GO:0015914 51 30 0,000 0,0665277 0,08332413 ! ensheathment of neurons GO:0007272 57 30 0,000 0,0665277 0,08328077 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0665277 0,08323747 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0665277 0,0831942 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,0665277 0,08315098 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0665277 0,08310781 ! eye morphogenesis GO:0048592 60 30 0,000 0,0665277 0,08306468 ! regulation of B cell activation GO:0050864 50 30 0,000 0,0665277 0,0830216 ! response to heat GO:0009408 50 30 0,000 0,0665277 0,08297856 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06866848 0,08560433 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06866848 0,08556 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06866848 0,08551571 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06866848 0,08547147 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06866848 0,08542728 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06866848 0,08538313 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06866848 0,08533903 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06866848 0,08529497 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06866848 0,08525096 ! ovulation cycle process GO:0022602 49 31 0,000 0,06866848 0,08520699 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06866848 0,08516307 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06866848 0,0851192 ! peptide transport GO:0015833 55 31 0,000 0,06866848 0,08507536 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06866848 0,08503158 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06866848 0,08498784 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06866848 0,08494414 ! mesoderm formation GO:0001707 69 31 0,000 0,06866848 0,08490049 ! natural killer cell activation GO:0030101 45 31 0,000 0,06866848 0,08485689 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06866848 0,08481333 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06866848 0,08476981 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06866848 0,08472634 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06866848 0,08468291 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06866848 0,08463953 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07080442 0,08722756 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07080442 0,08718292 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07080442 0,08713833 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07080442 0,08709378 ! cholesterol transport GO:0030301 56 32 0,000 0,07080442 0,08704927 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07080442 0,08700482 ! spliceosome assembly GO:0000245 67 32 0,000 0,07080442 0,0869604 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07080442 0,08691603 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07080442 0,08687171 ! response to ionizing radiation GO:0010212 65 32 0,000 0,07080442 0,08682744 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07080442 0,0867832 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07080442 0,08673902 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,07080442 0,08669487 ! muscle cell development GO:0055001 49 32 0,000 0,07080442 0,08665078 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07080442 0,08660673 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07080442 0,08656272 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07080442 0,08651875 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07080442 0,08647484 ! ovulation cycle GO:0042698 51 32 0,000 0,07080442 0,08643096 ! peripheral nervous system development GO:0007422 64 32 0,000 0,07080442 0,08638713 ! hindbrain development GO:0030902 61 32 0,000 0,07080442 0,08634335 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07080442 0,08629961 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07080442 0,08625591 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,07080442 0,08621226 ! gene silencing GO:0016458 65 32 0,000 0,07080442 0,08616865 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,07293553 0,08871733 ! post-embryonic development GO:0009791 69 33 0,000 0,07293553 0,0886725 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,07293553 0,08862772 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07293553 0,08858298 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07293553 0,08853829 ! formation of primary germ layer GO:0001704 72 33 0,000 0,07293553 0,08849364 ! cell fate specification GO:0001708 52 33 0,000 0,07293553 0,08844903 ! sterol transport GO:0015918 57 33 0,000 0,07293553 0,08840448 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07293553 0,08835996 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07293553 0,08831549 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,07293553 0,08827107 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07293553 0,08822669 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07506182 0,09075314 ! glial cell differentiation GO:0010001 63 34 0,000 0,07506182 0,09070756 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07506182 0,09066202 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07506182 0,09061653 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07506182 0,09057109 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07506182 0,09052569 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07506182 0,09048033 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07506182 0,09043503 ! mismatch repair GO:0006298 46 34 0,000 0,07506182 0,09038976 ! spermatid development GO:0007286 63 34 0,000 0,07506182 0,09034455 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07506182 0,09029937 ! placenta development GO:0001890 53 34 0,000 0,07506182 0,09025425 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,07506182 0,09020916 ! regulation of muscle development GO:0048634 70 35 0,000 0,07718331 0,09271246 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07718331 0,09266619 ! negative regulation of secretion GO:0051048 63 35 0,000 0,07718331 0,09261997 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,07718331 0,0925738 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07718331 0,09252768 ! female gonad development GO:0008585 58 35 0,000 0,07718331 0,0924816 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,07718331 0,09243556 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,07718331 0,09238958 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,07718331 0,09234363 ! cytokine production GO:0001816 59 35 0,000 0,07718331 0,09229774 ! neural tube formation GO:0001841 67 35 0,000 0,07718331 0,09225189 ! vesicle localization GO:0051648 64 35 0,000 0,07718331 0,09220608 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0793 0,09468775 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0793 0,09464078 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0793 0,09459386 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0793 0,09454698 ! cell junction organization GO:0034330 86 36 0,000 0,0793 0,09450015 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0793 0,09445337 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0793 0,09440664 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0793 0,09435995 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0793 0,0943133 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0793 0,09426671 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0793 0,09422015 ! aerobic respiration GO:0009060 55 36 0,000 0,0793 0,09417365 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,0793 0,09412719 ! embryonic organ development GO:0048568 57 36 0,000 0,0793 0,09408078 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,0793 0,09403441 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,0793 0,09398808 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08141191 0,09644365 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08141191 0,09639619 ! meiosis I GO:0007127 65 37 0,000 0,08141191 0,09634878 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,08141191 0,09630141 ! sister chromatid segregation GO:0000819 58 37 0,000 0,08141191 0,09625408 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08141191 0,09620681 ! organic anion transport GO:0015711 68 37 0,000 0,08141191 0,09615958 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,08141191 0,0961124 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,08141191 0,09606526 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08141191 0,09601817 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,08141191 0,09597112 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08141191 0,09592412 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,08141191 0,09587717 ! spermatid differentiation GO:0048515 66 37 0,000 0,08141191 0,09583027 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,08351905 0,09826251 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,08351905 0,09821448 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,08351905 0,0981665 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,08351905 0,09811857 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,08351905 0,09807068 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,08351905 0,09802284 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,08351905 0,09797505 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,08351905 0,0979273 ! lipid homeostasis GO:0055088 67 38 0,000 0,08351905 0,0978796 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,08351905 0,09783195 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,08351905 0,09778434 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,08351905 0,09773678 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,08351905 0,09768927 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,08351905 0,0976418 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mRNA catabolic process GO:0006402 71 39 0,000 0,08562142 0,10005106 ! learning GO:0007612 77 39 0,000 0,08562142 0,10000249 ! ear morphogenesis GO:0042471 60 39 0,000 0,08562142 0,09995397 ! organic ether metabolic process GO:0018904 55 39 0,000 0,08562142 0,09990549 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,08562142 0,09985707 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08562142 0,09980869 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,08562142 0,09976035 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,08562142 0,09971207 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,08562142 0,09966383 ! RNA modification GO:0009451 57 39 0,000 0,08562142 0,09961563 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08562142 0,09956749 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08771903 0,10195748 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08771903 0,10190825 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08771903 0,10185907 ! feeding behavior GO:0007631 59 40 0,000 0,08771903 0,10180993 ! negative regulation of binding GO:0051100 72 40 0,000 0,08771903 0,10176085 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08771903 0,1017118 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08771903 0,10166281 ! maintenance of protein location GO:0045185 91 40 0,000 0,08771903 0,10161386 ! cytokinesis GO:0000910 72 40 0,000 0,08771903 0,10156496 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08981191 0,10393817 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08981191 0,1038882 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08981191 0,10383827 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08981191 0,1037884 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08981191 0,10373857 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08981191 0,1036888 ! T cell differentiation GO:0030217 81 41 0,000 0,08981191 0,10363906 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08981191 0,10358938 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08981191 0,10353975 ! female gamete generation GO:0007292 61 41 0,000 0,08981191 0,10349016 ! polyol metabolic process GO:0019751 66 41 0,000 0,08981191 0,10344062 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08981191 0,10339112 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,09190005 0,10574439 ! regulation of tube size GO:0035150 71 42 0,000 0,09190005 0,10569384 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,09190005 0,10564335 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,09190005 0,10559289 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,09190005 0,10554249 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,09190005 0,10549214 ! neuron migration GO:0001764 79 42 0,000 0,09190005 0,10544183 ! regulation of protein secretion GO:0050708 71 42 0,000 0,09190005 0,10539157 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,09190005 0,10534136 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,09398347 0,10767821 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09398347 0,10762696 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09398347 0,10757575 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09398347 0,1075246 ! glucose transport GO:0015758 65 43 0,000 0,09398347 0,10747349 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09398347 0,10742244 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09398347 0,10737143 ! neural tube development GO:0021915 77 43 0,000 0,09398347 0,10732047 ! striated muscle contraction GO:0006941 77 43 0,000 0,09398347 0,10726956 ! phagocytosis GO:0006909 90 43 0,000 0,09398347 0,1072187 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09398347 0,10716788 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09606218 0,10948631 ! hexose transport GO:0008645 67 44 0,000 0,09606218 0,10943447 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,09606218 0,10938268 ! double-strand break repair GO:0006302 81 44 0,000 0,09606218 0,10933094 ! biopolymer methylation GO:0043414 84 44 0,000 0,09606218 0,10927925 ! B cell differentiation GO:0030183 107 44 0,000 0,09606218 0,1092276 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09606218 0,10917601 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09606218 0,10912446 ! developmental growth GO:0048589 82 44 0,000 0,09606218 0,10907296 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09606218 0,10902151 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09813619 0,11132281 ! glycolysis GO:0006096 65 45 0,000 0,09813619 0,11127035 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09813619 0,11121794 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09813619 0,11116557 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,09813619 0,11111326 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09813619 0,111061 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09813619 0,11100878 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09813619 0,11095662 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09813619 0,1109045 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09813619 0,11085243 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,10020551 0,11313677 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,10020551 0,11308371 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,10020551 0,11303069 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,10020551 0,11297772 ! positive regulation of defense response GO:0031349 76 47 0,000 0,10227015 0,11525152 ! response to calcium ion GO:0051592 81 47 0,000 0,10227015 0,11519756 ! endosome transport GO:0016197 108 47 0,000 0,10227015 0,11514365 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,10227015 0,1150898 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,10227015 0,11503599 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,10227015 0,11498224 ! methylation GO:0032259 90 47 0,000 0,10227015 0,11492853 ! protein homooligomerization GO:0051260 76 47 0,000 0,10227015 0,11487488 ! mitochondrial transport GO:0006839 82 48 0,000 0,10433013 0,11713406 ! Notch signaling pathway GO:0007219 96 48 0,000 0,10433013 0,11707942 ! cellular component disassembly GO:0022411 86 48 0,000 0,10433013 0,11702484 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10433013 0,11697031 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,10433013 0,11691583 ! activation of caspase activity GO:0006919 84 48 0,000 0,10433013 0,1168614 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10433013 0,11680702 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10433013 0,11675269 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,10433013 0,11669841 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,10433013 0,11664418 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10638544 0,11888684 ! regulation of action potential GO:0001508 95 49 0,000 0,10638544 0,11883165 ! regulation of ion transport GO:0043269 77 49 0,000 0,10638544 0,1187765 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10638544 0,11872141 ! peptide metabolic process GO:0006518 76 49 0,000 0,10638544 0,11866637 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10638544 0,11861138 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10638544 0,11855645 ! endocrine system development GO:0035270 104 49 0,000 0,10638544 0,11850156 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10638544 0,11844672 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10638544 0,11839194 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10638544 0,1183372 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10638544 0,11828252 ! neuromuscular process GO:0050905 99 50 0,000 0,1084361 0,12050682 ! inner ear development GO:0048839 79 50 0,000 0,1084361 0,12045119 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,1084361 0,1203956 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,1084361 0,12034007 ! viral infectious cycle GO:0019058 99 51 0,000 0,11048213 0,12255418 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,11048213 0,1224977 ! excretion GO:0007588 83 51 0,000 0,11048213 0,12244128 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,11048213 0,1223849 ! chromatin remodeling GO:0006338 109 51 0,000 0,11048213 0,12232858 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,11048213 0,12227231 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,11048213 0,1222161 ! vesicle organization GO:0016050 107 51 0,000 0,11048213 0,12215993 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,11048213 0,12210382 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,11048213 0,12204775 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,11252353 0,12424581 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,11252353 0,12418882 ! membrane fusion GO:0006944 110 52 0,000 0,11252353 0,12413187 ! amino acid activation GO:0043038 92 52 0,000 0,11252353 0,12407499 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,11252353 0,12401815 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,11456032 0,12620518 ! RNA catabolic process GO:0006401 93 53 0,000 0,11456032 0,12614742 ! regulation of translational initiation GO:0006446 82 53 0,000 0,11456032 0,12608972 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,11456032 0,12603206 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,11456032 0,12597446 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,11456032 0,12591691 ! cell maturation GO:0048469 100 53 0,000 0,11456032 0,12585941 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,11456032 0,12580197 ! response to UV GO:0009411 104 53 0,000 0,11456032 0,12574458 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,11659249 0,1279168 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11659249 0,12785849 ! cell recognition GO:0008037 85 54 0,000 0,11659249 0,12780024 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11659249 0,12774205 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11659249 0,1276839 ! chloride transport GO:0006821 90 55 0,000 0,11862007 0,12984526 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11862007 0,12978622 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,11862007 0,12972722 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11862007 0,12966828 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,11862007 0,1296094 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11862007 0,12955056 ! aging GO:0007568 103 55 0,000 0,11862007 0,12949178 ! gastrulation GO:0007369 112 55 0,000 0,11862007 0,12943306 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11862007 0,12937438 ! RNA elongation GO:0006354 79 55 0,000 0,11862007 0,12931576 ! nuclear export GO:0051168 97 55 0,000 0,11862007 0,1292572 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11862007 0,12919868 ! regulation of actin filament length GO:0030832 105 56 0,000 0,12064306 0,13134263 ! sensory perception of smell GO:0007608 80 56 0,000 0,12064306 0,13128322 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,12064306 0,13122387 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,12064306 0,13116458 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,12064306 0,13110533 ! regulation of DNA replication GO:0006275 101 56 0,000 0,12064306 0,13104614 ! proton transport GO:0015992 94 56 0,000 0,12064306 0,13098701 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,12064306 0,13092793 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,12266148 0,1330584 ! muscle fiber development GO:0048747 112 57 0,000 0,12266148 0,13299843 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,12266148 0,13293852 ! maintenance of location GO:0051235 118 57 0,000 0,12266148 0,13287867 ! hydrogen transport GO:0006818 97 58 0,000 0,12467533 0,13499948 ! regulation of endocytosis GO:0030100 91 58 0,000 0,12467533 0,13493875 ! adult behavior GO:0030534 99 58 0,000 0,12467533 0,13487808 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,12467533 0,13481746 ! positive regulation of secretion GO:0051047 95 59 0,000 0,12668463 0,13692867 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12668463 0,13686718 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12668463 0,13680575 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,12668463 0,13674437 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,12668463 0,13668305 ! establishment of organelle localization GO:0051656 109 59 0,000 0,12668463 0,13662179 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12868938 0,13872161 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,12868938 0,13865949 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12868938 0,13859742 ! camera-type eye development GO:0043010 116 60 0,000 0,12868938 0,13853541 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,13068959 0,14062574 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,13068959 0,14056288 ! mesoderm development GO:0007498 119 61 0,000 0,13068959 0,14050007 ! tRNA processing GO:0008033 89 61 0,000 0,13068959 0,14043732 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,13068959 0,14037462 ! ear development GO:0043583 103 62 0,000 0,13268528 0,14245461 ! viral reproductive process GO:0022415 126 62 0,000 0,13268528 0,14239107 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,13268528 0,14232759 ! gonad development GO:0008406 98 62 0,000 0,13268528 0,14226416 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,13268528 0,14220079 ! regulation of mitosis GO:0007088 105 63 0,000 0,13467645 0,1442705 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,13467645 0,14420629 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,13467645 0,14414215 ! detection of external stimulus GO:0009581 91 63 0,000 0,13467645 0,14407805 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,13467645 0,14401402 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13666312 0,14607351 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13666312 0,14600864 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,13666312 0,14594384 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13666312 0,14587909 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13666312 0,1458144 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13864529 0,14786373 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13864529 0,14779822 ! germ cell development GO:0007281 118 65 0,000 0,13864529 0,14773276 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,13864529 0,14766736 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,14062298 0,14970747 ! actin filament organization GO:0007015 148 66 0,000 0,14062298 0,14964126 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,14062298 0,14957511 ! secondary metabolic process GO:0019748 116 66 0,000 0,14062298 0,14950901 ! developmental maturation GO:0021700 116 66 0,000 0,14062298 0,14944297 ! cell projection assembly GO:0030031 120 66 0,000 0,14062298 0,14937699 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,14259619 0,1514062 ! chromosome segregation GO:0007059 113 67 0,000 0,14259619 0,15133941 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,14259619 0,15127268 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,14259619 0,15120601 ! hexose catabolic process GO:0019320 104 67 0,000 0,14259619 0,1511394 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,14259619 0,15107285 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,14259619 0,15100636 ! adaptive immune response GO:0002250 119 67 0,000 0,14259619 0,15093992 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,14259619 0,15087355 ! amino acid transport GO:0006865 125 68 0,000 0,14456494 0,15288934 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,14456494 0,15282217 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,14456494 0,15275505 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,14456494 0,15268799 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,14456494 0,152621 ! regulation of lipase activity GO:0060191 130 68 0,000 0,14456494 0,15255406 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,14456494 0,15248718 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,14456494 0,15242035 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,14652923 0,15442371 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14652923 0,1543561 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14652923 0,15428855 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14652923 0,15422106 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14652923 0,15415362 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14652923 0,15408625 ! amine catabolic process GO:0009310 117 71 0,000 0,15044449 0,15813432 ! reproductive structure development GO:0048608 113 71 0,000 0,15044449 0,15806526 ! humoral immune response GO:0006959 109 71 0,000 0,15044449 0,15799627 ! B cell activation GO:0042113 160 71 0,000 0,15044449 0,15792733 ! regulation of immune effector process GO:0002697 137 71 0,000 0,15044449 0,15785846 ! acute inflammatory response GO:0002526 113 72 0,000 0,15239548 0,15983588 ! regulation of caspase activity GO:0043281 122 72 0,000 0,15239548 0,15976624 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,15239548 0,15969666 ! carbohydrate transport GO:0008643 110 72 0,000 0,15239548 0,15962713 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,15239548 0,15955767 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,15239548 0,15948826 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,15239548 0,15941892 ! learning or memory GO:0007611 147 73 0,000 0,15434205 0,16138504 ! regulation of blood pressure GO:0008217 125 73 0,000 0,15434205 0,16131493 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,15434205 0,16124488 ! axon guidance GO:0007411 139 73 0,000 0,15434205 0,1611749 ! fertilization GO:0009566 90 73 0,000 0,15434205 0,16110498 ! transition metal ion transport GO:0000041 126 74 0,000 0,15628421 0,1630615 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15628421 0,16299082 ! meiosis GO:0007126 121 74 0,000 0,15628421 0,1629202 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,15628421 0,16284964 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15628421 0,16277914 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,15628421 0,16270871 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,15628421 0,16263833 ! organelle localization GO:0051640 136 74 0,000 0,15628421 0,16256801 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,15822198 0,16451257 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15822198 0,16444151 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15822198 0,1643705 ! meiotic cell cycle GO:0051321 122 75 0,000 0,15822198 0,16429956 ! rhythmic process GO:0048511 128 75 0,000 0,15822198 0,16422868 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,15822198 0,16415787 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,16015536 0,16609216 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,16015536 0,1660206 ! defense response to bacterium GO:0042742 89 76 0,000 0,16015536 0,1659491 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,16015536 0,16587766 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,16015536 0,16580629 ! regulation of catabolic process GO:0009894 161 76 0,000 0,16015536 0,16573497 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,16208437 0,16765907 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,16208437 0,16758702 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,16208437 0,16751503 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,16208437 0,16744311 ! blood coagulation GO:0007596 146 78 0,000 0,16400901 0,16935866 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,16400901 0,16928601 ! protein oligomerization GO:0051259 139 78 0,000 0,16400901 0,16921341 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,16592929 0,17112125 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,16592929 0,17104794 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,16592929 0,17097468 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,16592929 0,17090149 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16784523 0,17280087 ! response to metal ion GO:0010038 140 80 0,000 0,16784523 0,17272696 ! muscle cell differentiation GO:0042692 159 80 0,000 0,16784523 0,17265311 ! inorganic anion transport GO:0015698 138 80 0,000 0,16784523 0,17257933 ! T cell activation GO:0042110 168 81 0,000 0,16975683 0,17447028 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,16975683 0,17439578 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,16975683 0,17432135 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,16975683 0,17424698 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16975683 0,17417268 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,1716641 0,17605448 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,1716641 0,17597947 ! response to drug GO:0042493 143 82 0,000 0,1716641 0,17590452 ! response to nutrient GO:0007584 125 82 0,000 0,1716641 0,17582964 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,1716641 0,17575482 ! regulation of lyase activity GO:0051339 160 83 0,000 0,17356705 0,17762753 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,1754657 0,17949424 ! hemostasis GO:0007599 158 84 0,000 0,1754657 0,17941796 ! negative regulation of transport GO:0051051 153 84 0,000 0,1754657 0,17934174 ! regulation of ligase activity GO:0051340 142 84 0,000 0,1754657 0,17926559 ! response to unfolded protein GO:0006986 131 85 0,000 0,17736004 0,18112405 ! nucleosome assembly GO:0006334 122 85 0,000 0,17736004 0,1810472 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17736004 0,18097042 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,17736004 0,18089371 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 0,000 0,1792501 0,18274395 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,1792501 0,18266655 ! chromatin assembly GO:0031497 124 86 0,000 0,1792501 0,18258922 ! mitochondrion organization GO:0007005 148 86 0,000 0,1792501 0,18251195 ! alcohol catabolic process GO:0046164 130 86 0,000 0,1792501 0,18243474 ! amine transport GO:0015837 155 86 0,000 0,1792501 0,1823576 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,18113587 0,18419819 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,18113587 0,18412037 ! cellular respiration GO:0045333 135 88 0,000 0,18301738 0,18595431 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,18301738 0,18587582 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,18301738 0,18579739 ! cellular defense response GO:0006968 114 89 0,000 0,18489462 0,18762398 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,18676762 0,18944473 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,18676762 0,18936489 ! sex differentiation GO:0007548 145 90 0,000 0,18676762 0,18928513 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,18676762 0,18920543 ! sterol metabolic process GO:0016125 152 91 0,000 0,18863637 0,19101814 ! response to protein stimulus GO:0051789 149 91 0,000 0,18863637 0,19093778 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18863637 0,19085749 ! regulation of defense response GO:0031347 149 92 0,000 0,19050089 0,19266294 ! nucleosome organization GO:0034728 138 92 0,000 0,19050089 0,19258199 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,19050089 0,19250111 ! vitamin metabolic process GO:0006766 139 92 0,000 0,19050089 0,1924203 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,19236119 0,1942178 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,19236119 0,19413633 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,19236119 0,19405493 ! regulation of membrane potential GO:0042391 164 93 0,000 0,19236119 0,1939736 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,19236119 0,19389234 ! female pregnancy GO:0007565 164 94 0,000 0,19421727 0,19568122 ! transcription initiation GO:0006352 153 94 0,000 0,19421727 0,19559931 ! regulation of T cell activation GO:0050863 158 94 0,000 0,19421727 0,19551747 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,19606915 0,1972992 ! forebrain development GO:0030900 188 95 0,000 0,19606915 0,19721672 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,19606915 0,1971343 ! leukocyte differentiation GO:0002521 202 96 0,000 0,19791684 0,1989089 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,19791684 0,19882585 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,19791684 0,19874287 ! detection of stimulus GO:0051606 151 96 0,000 0,19791684 0,19865996 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,19976034 0,20042676 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19976034 0,20034322 ! protein ubiquitination GO:0016567 217 97 0,000 0,19976034 0,20025974 ! response to virus GO:0009615 160 98 0,000 0,20159967 0,20201949 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,20159967 0,20193538 ! interphase GO:0051325 213 98 0,000 0,20159967 0,20185135 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,20159967 0,20176739 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,20343482 0,20351941 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,20343482 0,20343482