pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/905-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! epithelial to mesenchymal transition GO:0001837 30 15 3,000 1,962E-08 4,793E-05 ! positive regulation of ossification GO:0045778 50 20 3,000 6,911E-08 8,442E-05 ! positive regulation of bone remodeling GO:0046852 54 22 3,000 1,04E-07 8,471E-05 GO:0034105|positive regulation of tissue remodeling, ! salivary gland morphogenesis GO:0007435 14 6 2,000 1,521E-07 9,289E-05 ! SMAD protein nuclear translocation GO:0007184 21 10 2,000 9,073E-07 4,433E-04 ! salivary gland development GO:0007431 28 10 2,000 9,073E-07 3,694E-04 ! mesenchymal cell development GO:0014031 94 41 3,000 1,399E-06 4,884E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! exocrine system development GO:0035272 34 13 2,000 2,153E-06 6,575E-04 ! gland morphogenesis GO:0022612 31 13 2,000 2,153E-06 5,845E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 2,736E-06 6,685E-04 GO:0060675|ureteric bud morphogenesis, ! positive regulation of bone mineralization GO:0030501 32 14 2,000 2,736E-06 6,077E-04 ! regulation of ossification GO:0030278 123 50 3,000 3,14E-06 6,392E-04 ! positive regulation of biomineral formation GO:0070169 33 15 2,000 3,416E-06 6,419E-04 ! dopamine metabolic process GO:0042417 35 15 2,000 3,416E-06 5,96E-04 ! regulation of bone remodeling GO:0046850 143 57 3,000 5,329E-06 8,679E-04 ! regulation of tissue remodeling GO:0034103 146 58 3,000 5,715E-06 8,726E-04 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 2,000 6,099E-06 8,765E-04 ! ureteric bud development GO:0001657 50 22 2,000 1,145E-05 1,553E-03 ! regulation of bone mineralization GO:0030500 54 23 2,000 1,314E-05 1,69E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 1,702E-05 2,079E-03 ! regulation of biomineral formation GO:0070167 56 25 2,000 1,702E-05 1,98E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 3,000 2,061E-05 2,289E-03 ! response to hypoxia GO:0001666 178 81 3,000 2,165E-05 2,299E-03 ! response to oxygen levels GO:0070482 183 83 3,000 2,384E-05 2,427E-03 ! catechol metabolic process GO:0009712 55 29 2,000 2,689E-05 2,627E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phenol metabolic process GO:0018958 56 30 2,000 2,983E-05 2,803E-03 ! spindle organization GO:0007051 50 32 2,000 3,634E-05 3,288E-03 ! metanephros development GO:0001656 81 32 2,000 3,634E-05 3,17E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 3,731E-05 3,143E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,919E-05 3,191E-03 ! positive regulation of filopodium assembly GO:0051491 16 5 1,000 3,919E-05 3,088E-03 GO:0051489|regulation of filopodium assembly, ! muscle cell proliferation GO:0033002 12 5 1,000 3,919E-05 2,992E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 3,919E-05 2,901E-03 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 10 5 1,000 3,919E-05 2,816E-03 ! stem cell division GO:0017145 11 5 1,000 3,919E-05 2,735E-03 GO:0048103|somatic stem cell division, ! positive regulation of cell development GO:0010720 85 36 2,000 5,201E-05 3,529E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 5,871E-05 3,876E-03 ! regulation of dendrite development GO:0050773 16 6 1,000 5,871E-05 3,774E-03 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 2,000 6,629E-05 4,152E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,208E-05 5,013E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 8,208E-05 4,891E-03 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 8,208E-05 4,774E-03 GO:0031958|corticosteroid receptor signaling pathway, ! glucocorticoid metabolic process GO:0008211 11 7 1,000 8,208E-05 4,663E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 8,208E-05 4,557E-03 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 9,537E-05 5,178E-03 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 1,02E-04 5,419E-03 ! cell growth GO:0016049 90 46 2,000 1,09E-04 5,666E-03 ! ER overload response GO:0006983 13 8 1,000 1,093E-04 5,563E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,093E-04 5,449E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 1,093E-04 5,34E-03 ! hormone catabolic process GO:0042447 17 8 1,000 1,093E-04 5,236E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 1,238E-04 5,818E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,403E-04 6,469E-03 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 1,000 1,403E-04 6,349E-03 ! microtubule bundle formation GO:0001578 22 9 1,000 1,403E-04 6,234E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 1,485E-04 6,477E-03 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 1,573E-04 6,743E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,752E-04 7,38E-03 ! positive regulation of heart contraction GO:0045823 17 10 1,000 1,752E-04 7,255E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,752E-04 7,134E-03 GO:0045685|regulation of glial cell differentiation, ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,752E-04 7,017E-03 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,761E-04 6,938E-03 ! heart morphogenesis GO:0003007 105 57 2,000 2,068E-04 8,02E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 2,139E-04 8,164E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,139E-04 8,038E-03 ! cardiac cell differentiation GO:0035051 36 11 1,000 2,139E-04 7,916E-03 ! kidney development GO:0001822 133 60 2,000 2,409E-04 8,782E-03 ! regulation of cell projection assembly GO:0060491 33 12 1,000 2,563E-04 9,208E-03 ! histone acetylation GO:0016573 27 12 1,000 2,563E-04 9,075E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,563E-04 8,945E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 2,563E-04 8,819E-03 ! mitotic spindle organization GO:0007052 23 12 1,000 2,563E-04 8,697E-03 ! negative regulation of cell projection organization GO:0031345 42 13 1,000 3,025E-04 0,01012392 ! positive regulation of cell growth GO:0030307 24 13 1,000 3,025E-04 9,987E-03 ! regulation of epidermis development GO:0045682 19 13 1,000 3,025E-04 9,854E-03 ! activation of MAPK activity GO:0000187 124 67 2,000 3,338E-04 0,01073035 ! regulation of cellular response to stress GO:0080135 142 68 2,000 3,487E-04 0,01106399 ! hair follicle morphogenesis GO:0031069 27 14 1,000 3,525E-04 0,01103982 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 3,525E-04 0,01090008 ! urogenital system development GO:0001655 149 69 2,000 3,641E-04 0,01111724 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,062E-04 0,01225062 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 4,126E-04 0,01229328 ! positive regulation of cell size GO:0045793 29 16 1,000 4,636E-04 0,01364569 ! bone remodeling GO:0046849 28 16 1,000 4,636E-04 0,01348324 ! regulation of neurotransmitter secretion GO:0046928 35 16 1,000 4,636E-04 0,01332462 ! regulation of dephosphorylation GO:0035303 43 16 1,000 4,636E-04 0,01316968 ! negative regulation of immune response GO:0050777 38 16 1,000 4,636E-04 0,0130183 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 4,636E-04 0,01287037 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 5,247E-04 0,0144039 GO:0031114|regulation of microtubule depolymerization, ! neutrophil chemotaxis GO:0030593 29 17 1,000 5,247E-04 0,01424385 ! steroid catabolic process GO:0006706 34 17 1,000 5,247E-04 0,01408733 ! regulation of synaptic transmission GO:0050804 159 79 2,000 5,417E-04 0,01438385 ! epidermis morphogenesis GO:0048730 43 18 1,000 5,896E-04 0,01548739 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 5,896E-04 0,01532263 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 5,896E-04 0,01516134 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 5,896E-04 0,01500341 ! protein import into nucleus GO:0006606 174 82 2,000 6,04E-04 0,01521275 ! nuclear import GO:0051170 177 83 2,000 6,258E-04 0,01559989 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 6,581E-04 0,01623939 ! pigmentation during development GO:0048066 42 19 1,000 6,581E-04 0,01607699 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 6,581E-04 0,01591781 ! proximal/distal pattern formation GO:0009954 33 19 1,000 6,581E-04 0,01576176 ! regulation of transmission of nerve impulse GO:0051969 167 85 2,000 6,708E-04 0,01590999 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,303E-04 0,0171541 ! protein amino acid acetylation GO:0006473 41 20 1,000 7,303E-04 0,01699072 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,303E-04 0,01683043 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 7,303E-04 0,01667314 ! tube morphogenesis GO:0035239 194 89 2,000 7,669E-04 0,01734683 ! protein localization in nucleus GO:0034504 192 89 2,000 7,669E-04 0,01718768 ! regulation of neurological system process GO:0031644 175 89 2,000 7,669E-04 0,01703143 ! lipid phosphorylation GO:0046834 43 21 1,000 8,061E-04 0,0177412 ! regulation of neurotransmitter transport GO:0051588 44 21 1,000 8,061E-04 0,01758279 ! collagen fibril organization GO:0030199 62 21 1,000 8,061E-04 0,01742719 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 8,061E-04 0,01727432 ! gland development GO:0048732 220 91 2,000 8,18E-04 0,01737756 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 8,713E-04 0,01834965 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 8,856E-04 0,01849063 ! peptidyl-serine modification GO:0018209 50 22 1,000 8,856E-04 0,01833393 ! activation of JUN kinase activity GO:0007257 47 22 1,000 8,856E-04 0,01817987 ! biogenic amine metabolic process GO:0006576 162 97 2,000 9,843E-04 0,02003926 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,055E-03 0,02130727 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,055E-03 0,02113262 ! molting cycle process GO:0022404 52 26 1,000 1,239E-03 0,02461846 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,239E-03 0,02441993 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 1,239E-03 0,02422457 ! negative regulation of cell development GO:0010721 83 26 1,000 1,239E-03 0,02403231 GO:0050768|negative regulation of neurogenesis, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 1,239E-03 0,02384308 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,239E-03 0,02365681 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 1,239E-03 0,02347342 ! positive regulation of cell projection organization GO:0031346 66 27 1,000 1,337E-03 0,02512383 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 1,337E-03 0,02493205 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,337E-03 0,02474317 ! protein amino acid acylation GO:0043543 59 28 1,000 1,438E-03 0,02641204 ! dendrite development GO:0016358 67 28 1,000 1,438E-03 0,02621493 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,438E-03 0,02602075 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 1,438E-03 0,02582942 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 1,542E-03 0,02750469 ! somitogenesis GO:0001756 52 29 1,000 1,542E-03 0,02730538 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 1,762E-03 0,03096842 ! BMP signaling pathway GO:0030509 71 32 1,000 1,877E-03 0,03275475 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 1,996E-03 0,03457606 ! leukocyte chemotaxis GO:0030595 55 33 1,000 1,996E-03 0,03433256 GO:0060326|cell chemotaxis, ! regulation of synaptic plasticity GO:0048167 78 35 1,000 2,243E-03 0,03831966 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 2,243E-03 0,03805356 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 2,372E-03 0,03996258 ! odontogenesis GO:0042476 74 37 1,000 2,504E-03 0,04190276 ! tissue remodeling GO:0048771 78 37 1,000 2,504E-03 0,0416177 ! regulation of microtubule-based process GO:0032886 86 37 1,000 2,504E-03 0,0413365 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 2,64E-03 0,04328432 ! regulation of protein stability GO:0031647 77 38 1,000 2,64E-03 0,04299576 ! glycogen metabolic process GO:0005977 63 38 1,000 2,64E-03 0,04271102 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 2,64E-03 0,04243003 ! regulation of neuron projection development GO:0010975 102 39 1,000 2,779E-03 0,04437402 ! glucan metabolic process GO:0044042 64 39 1,000 2,779E-03 0,04408588 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 2,922E-03 0,04604743 ! gliogenesis GO:0042063 91 41 1,000 3,067E-03 0,04803661 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 3,217E-03 0,05005267 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 3,369E-03 0,0520949 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 3,369E-03 0,05176726 ! energy reserve metabolic process GO:0006112 76 44 1,000 3,525E-03 0,05382407 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 3,525E-03 0,05348976 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 3,684E-03 0,05556054 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 3,847E-03 0,0576554 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 3,847E-03 0,05730384 ! leukocyte migration GO:0050900 75 46 1,000 3,847E-03 0,05695655 ! pigmentation GO:0043473 103 46 1,000 3,847E-03 0,05661344 ! positive regulation of protein transport GO:0051222 80 46 1,000 3,847E-03 0,05627443 ! regulation of JNK cascade GO:0046328 104 47 1,000 4,013E-03 0,05835052 ! response to insulin stimulus GO:0032868 98 47 1,000 4,013E-03 0,05800525 ! positive regulation of cell cycle GO:0045787 96 48 1,000 4,182E-03 0,0600938 ! positive regulation of DNA binding GO:0043388 83 48 1,000 4,182E-03 0,05974237 ! JNK cascade GO:0007254 106 49 1,000 4,354E-03 0,06184286 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 4,708E-03 0,06649018 ! negative regulation of immune system process GO:0002683 101 51 1,000 4,708E-03 0,06610805 ! positive regulation of binding GO:0051099 88 52 1,000 4,891E-03 0,06827165 ! response to estrogen stimulus GO:0043627 98 52 1,000 4,891E-03 0,06788374 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 4,891E-03 0,06750022 ! histone modification GO:0016570 104 52 1,000 4,891E-03 0,067121 ! positive regulation of growth GO:0045927 96 53 1,000 5,076E-03 0,06927438 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 5,076E-03 0,06888952 ! cartilage development GO:0051216 99 53 1,000 5,076E-03 0,06850892 ! embryonic skeletal system development GO:0048706 101 54 1,000 5,264E-03 0,07066207 ! covalent chromatin modification GO:0016569 115 54 1,000 5,264E-03 0,07027594 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 5,651E-03 0,07502474 ! regulation of intracellular transport GO:0032386 108 57 1,000 5,849E-03 0,07723331 ! positive regulation of cell migration GO:0030335 137 58 1,000 6,05E-03 0,07945942 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 6,05E-03 0,0790345 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 6,05E-03 0,0786141 ! lipid modification GO:0030258 112 60 1,000 6,461E-03 0,08351819 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 6,672E-03 0,0857846 ! regulation of heart contraction GO:0008016 123 61 1,000 6,672E-03 0,08533547 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 6,672E-03 0,08489101 ! skeletal system morphogenesis GO:0048705 118 63 1,000 7,102E-03 0,08989622 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 7,322E-03 0,09219933 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 7,322E-03 0,09172651 ! positive regulation of cell motion GO:0051272 157 65 1,000 7,544E-03 0,09403483 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 7,77E-03 0,09635742 ! negative regulation of cell growth GO:0030308 142 67 1,000 7,999E-03 0,0986939 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 7,999E-03 0,09819796 GO:0035113|embryonic appendage morphogenesis, ! extracellular matrix organization GO:0030198 146 68 1,000 8,231E-03 0,1005387 ! negative regulation of cell size GO:0045792 144 69 1,000 8,466E-03 0,10289265 ! cellular hormone metabolic process GO:0034754 120 69 1,000 8,466E-03 0,10238328 ! lung development GO:0030324 165 69 1,000 8,466E-03 0,10187893 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 8,944E-03 0,10711113 ! appendage morphogenesis GO:0035107 150 72 1,000 9,188E-03 0,10949353 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 9,188E-03 0,10896201 ! appendage development GO:0048736 151 73 1,000 9,435E-03 0,11134729 GO:0060173|limb development, ! respiratory system development GO:0060541 175 74 1,000 9,684E-03 0,11374417 ! regulation of transcription factor activity GO:0051090 137 75 1,000 9,937E-03 0,11615234 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 9,937E-03 0,11559923 ! eye development GO:0001654 155 75 1,000 9,937E-03 0,11505137 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 9,948E-03 0,11464074 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 9,948E-03 0,11410252 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 9,948E-03 0,11356933 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,948E-03 0,1130411 ! positive regulation of helicase activity GO:0051096 12 5 0,000 9,948E-03 0,11251776 ! neuron fate determination GO:0048664 7 5 0,000 9,948E-03 0,11199925 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,948E-03 0,11148549 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 9,948E-03 0,11097642 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 9,948E-03 0,11047198 ! polyol transport GO:0015791 12 5 0,000 9,948E-03 0,10997211 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,948E-03 0,10947674 ! response to superoxide GO:0000303 10 5 0,000 9,948E-03 0,10898581 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,948E-03 0,10849927 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 9,948E-03 0,10801705 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 9,948E-03 0,1075391 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,948E-03 0,10706536 ! female meiosis GO:0007143 10 5 0,000 9,948E-03 0,10659577 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 9,948E-03 0,10613029 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,948E-03 0,10566885 ! hypothalamus development GO:0021854 9 5 0,000 9,948E-03 0,10521141 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 9,948E-03 0,10475792 ! cobalt ion transport GO:0006824 11 5 0,000 9,948E-03 0,10430831 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 9,948E-03 0,10386255 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 9,948E-03 0,10342058 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,948E-03 0,10298236 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,948E-03 0,10254783 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 9,948E-03 0,10211696 ! embryonic camera-type eye development GO:0031076 12 5 0,000 9,948E-03 0,10168969 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,948E-03 0,10126599 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,948E-03 0,10084579 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 9,948E-03 0,10042908 ! transposition GO:0032196 9 5 0,000 9,948E-03 0,10001579 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 9,948E-03 0,09960589 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 9,948E-03 0,09919933 ! negative chemotaxis GO:0050919 16 5 0,000 9,948E-03 0,09879608 ! positive regulation of histone modification GO:0031058 6 5 0,000 9,948E-03 0,0983961 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,948E-03 0,09799934 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 9,948E-03 0,09760577 ! behavioral response to pain GO:0048266 10 5 0,000 9,948E-03 0,09721535 ! clathrin coat assembly GO:0048268 15 5 0,000 9,948E-03 0,09682803 ! Notch receptor processing GO:0007220 11 5 0,000 9,948E-03 0,0964438 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,948E-03 0,09606259 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 9,948E-03 0,0956844 ! micturition GO:0060073 9 5 0,000 9,948E-03 0,09530916 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,948E-03 0,09493686 ! copulation GO:0007620 9 5 0,000 9,948E-03 0,09456746 ! glial cell fate commitment GO:0021781 14 5 0,000 9,948E-03 0,09420092 ! protein maturation by protein folding GO:0022417 14 5 0,000 9,948E-03 0,09383721 ! bioluminescence GO:0008218 9 5 0,000 9,948E-03 0,09347629 ! spermidine metabolic process GO:0008216 7 5 0,000 9,948E-03 0,09311815 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,948E-03 0,09276273 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,948E-03 0,09241002 ! apoptotic cell clearance GO:0043277 23 5 0,000 9,948E-03 0,09205999 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,948E-03 0,09171259 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 9,948E-03 0,09136781 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,948E-03 0,0910256 ! grooming behavior GO:0007625 6 5 0,000 9,948E-03 0,09068596 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 9,948E-03 0,09034883 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,948E-03 0,09001421 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 9,948E-03 0,08968205 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,948E-03 0,08935234 ! response to protozoan GO:0001562 13 5 0,000 9,948E-03 0,08902504 ! positive regulation of glycolysis GO:0045821 13 5 0,000 9,948E-03 0,08870013 ! lymph vessel development GO:0001945 10 5 0,000 9,948E-03 0,08837759 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 9,948E-03 0,08805738 ! endochondral ossification GO:0001958 17 5 0,000 9,948E-03 0,08773948 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,948E-03 0,08742387 ! single strand break repair GO:0000012 8 5 0,000 9,948E-03 0,08711052 ! parathyroid gland development GO:0060017 14 5 0,000 9,948E-03 0,08679942 ! anagen GO:0042640 7 5 0,000 9,948E-03 0,08649052 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,948E-03 0,08618382 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,948E-03 0,08587928 ! cytokine secretion GO:0050663 15 5 0,000 9,948E-03 0,08557689 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 9,948E-03 0,08527662 ! ceramide catabolic process GO:0046514 7 5 0,000 9,948E-03 0,08497845 ! skeletal myofibril assembly GO:0014866 12 5 0,000 9,948E-03 0,08468236 ! smooth muscle tissue development GO:0048745 32 5 0,000 9,948E-03 0,08438832 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,948E-03 0,08409632 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,948E-03 0,08380633 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 9,948E-03 0,08351834 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,948E-03 0,08323232 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 9,948E-03 0,08294825 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,948E-03 0,08266611 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 9,948E-03 0,08238589 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,948E-03 0,08210756 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 9,948E-03 0,0818311 ! glycine biosynthetic process GO:0006545 7 5 0,000 9,948E-03 0,0815565 ! microvillus organization GO:0032528 8 5 0,000 9,948E-03 0,08128373 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 9,948E-03 0,08101279 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 9,948E-03 0,08074364 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 9,948E-03 0,08047628 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 9,948E-03 0,08021068 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 9,948E-03 0,07994683 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 9,948E-03 0,07968471 ! polyol catabolic process GO:0046174 9 5 0,000 9,948E-03 0,0794243 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 9,948E-03 0,07916559 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 9,948E-03 0,07890856 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 9,948E-03 0,07865319 ! muscle cell migration GO:0014812 8 5 0,000 9,948E-03 0,07839947 ! mitochondrial fission GO:0000266 8 5 0,000 9,948E-03 0,07814738 ! sister chromatid cohesion GO:0007062 15 5 0,000 9,948E-03 0,07789691 ! response to tumor necrosis factor GO:0034612 10 5 0,000 9,948E-03 0,07764804 ! mRNA transcription GO:0009299 10 5 0,000 9,948E-03 0,07740075 ! nerve growth factor processing GO:0032455 9 5 0,000 9,948E-03 0,07715504 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 9,948E-03 0,07691087 ! anaerobic glycolysis GO:0019642 6 5 0,000 9,948E-03 0,07666825 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,948E-03 0,07642716 ! monocyte activation GO:0042117 10 5 0,000 9,948E-03 0,07618758 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,948E-03 0,07594949 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,948E-03 0,07571289 ! response to food GO:0032094 6 5 0,000 9,948E-03 0,07547775 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,948E-03 0,07524408 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,948E-03 0,07501184 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 9,948E-03 0,07478104 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,948E-03 0,07455165 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 9,948E-03 0,07432366 ! forebrain neuron development GO:0021884 13 5 0,000 9,948E-03 0,07409706 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,948E-03 0,07387184 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 9,948E-03 0,07364799 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 9,948E-03 0,07342549 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,948E-03 0,07320433 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,948E-03 0,07298449 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 9,948E-03 0,07276598 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,948E-03 0,07254877 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 9,948E-03 0,07233285 ! lipid glycosylation GO:0030259 7 5 0,000 9,948E-03 0,07211821 ! nucleobase transport GO:0015851 6 5 0,000 9,948E-03 0,07190484 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,948E-03 0,07169273 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 9,948E-03 0,07148187 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 9,948E-03 0,07127225 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 9,948E-03 0,07106385 ! basic amino acid transport GO:0015802 12 5 0,000 9,948E-03 0,07085667 ! cellular glucose homeostasis GO:0001678 6 5 0,000 9,948E-03 0,07065069 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 9,948E-03 0,0704459 ! actin nucleation GO:0045010 11 5 0,000 9,948E-03 0,0702423 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,948E-03 0,07003987 ! depurination GO:0045007 5 5 0,000 9,948E-03 0,06983861 ! depyrimidination GO:0045008 10 5 0,000 9,948E-03 0,0696385 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,948E-03 0,06943953 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,948E-03 0,0692417 ! G2/M transition checkpoint GO:0031576 8 5 0,000 9,948E-03 0,06904499 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,948E-03 0,0688494 ! zinc ion homeostasis GO:0055069 9 5 0,000 9,948E-03 0,06865491 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 9,948E-03 0,06846151 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 9,948E-03 0,0682692 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,948E-03 0,06807797 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,948E-03 0,06788781 ! activated T cell proliferation GO:0050798 16 5 0,000 9,948E-03 0,06769871 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,948E-03 0,06751066 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 9,948E-03 0,06732365 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,948E-03 0,06713767 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,948E-03 0,06695272 ! gamma-delta T cell activation GO:0046629 6 5 0,000 9,948E-03 0,06676878 ! response to arsenic GO:0046685 11 5 0,000 9,948E-03 0,06658585 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 9,948E-03 0,06640392 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,948E-03 0,06622299 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 9,948E-03 0,06604303 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 9,948E-03 0,06586406 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 9,948E-03 0,06568604 ! response to mercury ion GO:0046689 8 5 0,000 9,948E-03 0,06550899 ! response to cadmium ion GO:0046686 7 5 0,000 9,948E-03 0,06533289 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 9,948E-03 0,06515774 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 9,948E-03 0,06498352 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 9,948E-03 0,06481023 ! bile acid biosynthetic process GO:0006699 7 5 0,000 9,948E-03 0,06463786 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 9,948E-03 0,06446641 ! ganglioside catabolic process GO:0006689 12 5 0,000 9,948E-03 0,06429586 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,948E-03 0,06412622 ! decidualization GO:0046697 11 5 0,000 9,948E-03 0,06395746 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 9,948E-03 0,0637896 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 9,948E-03 0,06362261 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 9,948E-03 0,06345649 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 9,948E-03 0,06329124 ! embryonic cleavage GO:0040016 6 5 0,000 9,948E-03 0,06312685 ! peroxisome fission GO:0016559 5 5 0,000 9,948E-03 0,06296331 ! histone demethylation GO:0016577 13 5 0,000 9,948E-03 0,06280061 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 9,948E-03 0,06263875 ! mitotic recombination GO:0006312 9 5 0,000 9,948E-03 0,06247773 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 9,948E-03 0,06231753 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,948E-03 0,06215815 ! metaphase plate congression GO:0051310 7 5 0,000 9,948E-03 0,06199958 ! regulation of sterol transport GO:0032371 7 5 0,000 9,948E-03 0,06184182 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,948E-03 0,06168486 ! enteric nervous system development GO:0048484 8 5 0,000 9,948E-03 0,0615287 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 9,948E-03 0,06137332 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 9,948E-03 0,06121873 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 9,948E-03 0,06106492 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,948E-03 0,06091187 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 9,948E-03 0,06075959 ! B cell homeostasis GO:0001782 13 5 0,000 9,948E-03 0,06060807 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 9,948E-03 0,0604573 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,948E-03 0,06030729 ! metaphase GO:0051323 11 5 0,000 9,948E-03 0,06015801 ! melatonin biosynthetic process GO:0030187 7 5 0,000 9,948E-03 0,06000947 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 9,948E-03 0,05986167 ! cellular response to nutrient GO:0031670 8 5 0,000 9,948E-03 0,05971459 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,948E-03 0,05956823 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 9,948E-03 0,05942258 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 9,948E-03 0,05927765 ! definitive hemopoiesis GO:0060216 14 5 0,000 9,948E-03 0,05913342 ! response to redox state GO:0051775 6 5 0,000 9,948E-03 0,05898989 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 9,948E-03 0,05884706 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 9,948E-03 0,05870492 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,948E-03 0,05856346 ! brown fat cell differentiation GO:0050873 7 5 0,000 9,948E-03 0,05842268 ! regulation of telomerase activity GO:0051972 7 5 0,000 9,948E-03 0,05828258 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,948E-03 0,05814315 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 9,948E-03 0,05800438 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,948E-03 0,05786628 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 9,948E-03 0,05772883 ! striatum development GO:0021756 14 5 0,000 9,948E-03 0,05759203 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 9,948E-03 0,05745588 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,948E-03 0,05732037 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,948E-03 0,0571855 ! neural plate morphogenesis GO:0001839 7 5 0,000 9,948E-03 0,05705126 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 9,948E-03 0,05691765 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,948E-03 0,05678466 ! T cell activation during immune response GO:0002286 9 5 0,000 9,948E-03 0,0566523 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,948E-03 0,05652055 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,948E-03 0,05638941 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 9,948E-03 0,05625888 ! neuroprotection GO:0043526 8 5 0,000 9,948E-03 0,05612895 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,948E-03 0,05599962 ! regulation of sensory perception GO:0051931 8 5 0,000 9,948E-03 0,05587089 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,948E-03 0,05574274 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,948E-03 0,05561519 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 9,948E-03 0,05548821 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 9,948E-03 0,05536181 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,948E-03 0,05523599 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 9,948E-03 0,05511074 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,948E-03 0,05498606 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 9,948E-03 0,05486193 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 9,948E-03 0,05473837 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 9,948E-03 0,05461536 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,948E-03 0,05449291 ! spindle assembly GO:0051225 6 5 0,000 9,948E-03 0,054371 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,948E-03 0,05424963 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,948E-03 0,05412881 ! protein palmitoylation GO:0018345 12 5 0,000 9,948E-03 0,05400853 ! drug metabolic process GO:0017144 7 5 0,000 9,948E-03 0,05388877 ! phospholipid scrambling GO:0017121 8 5 0,000 9,948E-03 0,05376955 ! organ regeneration GO:0031100 7 5 0,000 9,948E-03 0,05365085 ! carnitine metabolic process GO:0009437 8 5 0,000 9,948E-03 0,05353268 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,948E-03 0,05341503 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01045079 0,05598964 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,01097624 0,05867606 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,01124327 0,05997231 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,01124327 0,05984166 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01192629 0,06333896 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01192629 0,06320156 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01192629 0,06306476 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01192629 0,06292855 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01192629 0,06279293 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01192629 0,06265789 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01192629 0,06252343 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01192629 0,06238955 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01192629 0,06225624 ! response to oxygen radical GO:0000305 11 6 0,000 0,01192629 0,0621235 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01192629 0,06199132 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01192629 0,0618597 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01192629 0,06172864 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01192629 0,06159814 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01192629 0,06146819 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01192629 0,06133878 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01192629 0,06120992 ! forebrain regionalization GO:0021871 9 6 0,000 0,01192629 0,06108159 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01192629 0,06095381 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01192629 0,06082656 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01192629 0,06069983 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01192629 0,06057364 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01192629 0,06044797 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01192629 0,06032282 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01192629 0,06019818 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01192629 0,06007406 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01192629 0,05995045 ! malate metabolic process GO:0006108 13 6 0,000 0,01192629 0,05982735 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01192629 0,05970475 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01192629 0,05958266 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01192629 0,05946106 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01192629 0,05933996 ! protein refolding GO:0042026 15 6 0,000 0,01192629 0,05921935 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01192629 0,05909923 ! opsonization GO:0008228 8 6 0,000 0,01192629 0,0589796 ! mating behavior GO:0007617 7 6 0,000 0,01192629 0,05886045 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01192629 0,05874177 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01192629 0,05862358 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01192629 0,05850586 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01192629 0,05838862 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01192629 0,05827184 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01192629 0,05815553 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01192629 0,05803968 ! toxin metabolic process GO:0009404 11 6 0,000 0,01192629 0,05792429 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01192629 0,05780937 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01192629 0,05769489 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01192629 0,05758087 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01192629 0,0574673 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01192629 0,05735417 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01192629 0,05724149 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01192629 0,05712926 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01192629 0,05701746 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01192629 0,05690609 ! thymic T cell selection GO:0045061 16 6 0,000 0,01192629 0,05679517 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01192629 0,05668467 ! protein lipoylation GO:0009249 10 6 0,000 0,01192629 0,0565746 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01192629 0,05646496 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01192629 0,05635575 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01192629 0,05624695 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01192629 0,05613857 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01192629 0,05603062 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01192629 0,05592307 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01192629 0,05581594 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01192629 0,05570922 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01192629 0,0556029 ! hyperosmotic response GO:0006972 10 6 0,000 0,01192629 0,05549699 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01192629 0,05539148 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01192629 0,05528638 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01192629 0,05518167 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01192629 0,05507735 ! urea metabolic process GO:0019627 7 6 0,000 0,01192629 0,05497343 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01192629 0,05486991 ! neutrophil activation GO:0042119 7 6 0,000 0,01192629 0,05476677 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01192629 0,05466402 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01192629 0,05456165 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01192629 0,05445966 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01192629 0,05435806 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01192629 0,05425683 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01192629 0,05415599 ! neuron apoptosis GO:0051402 15 6 0,000 0,01192629 0,05405551 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01192629 0,05395541 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01192629 0,05385568 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01192629 0,05375631 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01192629 0,05365731 ! carnitine transport GO:0015879 10 6 0,000 0,01192629 0,05355868 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01192629 0,0534604 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01192629 0,05336249 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01192629 0,05326494 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01192629 0,05316774 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01192629 0,05307089 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01192629 0,0529744 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01192629 0,05287826 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01192629 0,05278246 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01192629 0,05268702 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01192629 0,05259191 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01192629 0,05249715 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01192629 0,05240273 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01192629 0,05230865 ! response to UV-C GO:0010225 14 6 0,000 0,01192629 0,05221491 ! astrocyte development GO:0014002 16 6 0,000 0,01192629 0,0521215 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01192629 0,05202843 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01192629 0,05193569 ! interaction with symbiont GO:0051702 14 6 0,000 0,01192629 0,05184327 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01192629 0,05175119 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01192629 0,05165943 ! response to copper ion GO:0046688 10 6 0,000 0,01192629 0,051568 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01192629 0,05147689 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01192629 0,0513861 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01192629 0,05129563 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01192629 0,05120548 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01192629 0,05111565 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01192629 0,05102613 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01192629 0,05093692 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01192629 0,05084803 ! hair follicle maturation GO:0048820 8 6 0,000 0,01192629 0,05075944 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01192629 0,05067117 ! Schwann cell development GO:0014044 15 6 0,000 0,01192629 0,05058319 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01192629 0,05049553 ! response to pheromone GO:0019236 6 6 0,000 0,01192629 0,05040817 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01192629 0,05032111 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01192629 0,05023435 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01192629 0,05014788 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01192629 0,05006172 ! subpallium development GO:0021544 15 6 0,000 0,01192629 0,04997585 ! neural tube patterning GO:0021532 8 6 0,000 0,01192629 0,04989027 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01192629 0,04980499 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01192629 0,04972 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01192629 0,0496353 ! G2 phase GO:0051319 16 6 0,000 0,01192629 0,04955088 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01192629 0,04946676 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01192629 0,04938292 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01192629 0,04929936 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01192629 0,04921608 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01192629 0,04913309 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01192629 0,04905037 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01192629 0,04896793 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01192629 0,04888577 ! receptor internalization GO:0031623 11 6 0,000 0,01192629 0,04880389 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01192629 0,04872227 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01192629 0,04864094 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01192629 0,04855987 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01192629 0,04847907 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 16 6 0,000 0,01192629 0,04839854 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01192629 0,04831828 ! protein destabilization GO:0031648 9 6 0,000 0,01192629 0,04823828 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01192629 0,04815855 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01192629 0,04807908 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01192629 0,04799987 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01192629 0,04792092 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01192629 0,04784223 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01192629 0,0477638 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01192629 0,04768563 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01192629 0,04760771 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01192629 0,04753005 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01192629 0,04745264 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01192629 0,04737548 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01192629 0,04729857 ! neural plate development GO:0001840 9 6 0,000 0,01192629 0,04722191 ! catecholamine transport GO:0051937 9 6 0,000 0,01192629 0,0471455 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01192629 0,04706934 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01192629 0,04699342 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01192629 0,04691775 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01192629 0,04684232 ! maternal placenta development GO:0001893 12 6 0,000 0,01192629 0,04676713 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01192629 0,04669218 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01192629 0,04661747 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01192629 0,046543 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01192629 0,04646877 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01192629 0,04639478 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01192629 0,04632102 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01192629 0,04624749 GO:0055081|anion homeostasis, ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,01206145 0,04669749 ! negative regulation of growth GO:0045926 168 85 1,000 0,01262101 0,04878658 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,01262101 0,0487095 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01262101 0,04863267 ! regulation of protein transport GO:0051223 165 87 1,000 0,01319174 0,05075184 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 1,000 0,01348126 0,05178417 ! regulation of DNA binding GO:0051101 167 89 1,000 0,01377355 0,05282383 ! tRNA transcription GO:0009304 17 7 0,000 0,01390032 0,05322647 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01390032 0,05314317 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01390032 0,05306013 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01390032 0,05297736 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01390032 0,05289484 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01390032 0,05281258 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01390032 0,05273057 ! sleep GO:0030431 16 7 0,000 0,01390032 0,05264882 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01390032 0,05256732 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01390032 0,05248607 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01390032 0,05240507 ! prostate gland development GO:0030850 14 7 0,000 0,01390032 0,05232432 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01390032 0,05224383 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01390032 0,05216357 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01390032 0,05208357 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01390032 0,05200381 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01390032 0,05192429 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01390032 0,05184502 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01390032 0,05176599 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01390032 0,05168719 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01390032 0,05160864 ! glycolipid transport GO:0046836 11 7 0,000 0,01390032 0,05153033 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01390032 0,05145225 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01390032 0,05137441 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01390032 0,05129681 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01390032 0,05121944 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01390032 0,0511423 ! mRNA stabilization GO:0048255 18 7 0,000 0,01390032 0,05106539 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01390032 0,05098872 ! fibril organization GO:0043206 17 7 0,000 0,01390032 0,05091227 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01390032 0,05083606 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01390032 0,05076007 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01390032 0,05068431 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01390032 0,05060877 ! lipoprotein transport GO:0042953 14 7 0,000 0,01390032 0,05053346 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01390032 0,05045837 ! rhythmic behavior GO:0007622 17 7 0,000 0,01390032 0,05038351 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01390032 0,05030887 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01390032 0,05023445 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01390032 0,05016025 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01390032 0,05008626 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01390032 0,0500125 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01390032 0,04993895 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01390032 0,04986562 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01390032 0,0497925 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01390032 0,0497196 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01390032 0,04964691 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01390032 0,04957443 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01390032 0,04950217 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01390032 0,04943011 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01390032 0,04935826 ! spinal cord patterning GO:0021511 14 7 0,000 0,01390032 0,04928663 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01390032 0,0492152 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01390032 0,04914397 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01390032 0,04907296 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01390032 0,04900214 ! adrenal gland development GO:0030325 17 7 0,000 0,01390032 0,04893154 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01390032 0,04886113 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01390032 0,04879093 ! ovulation GO:0030728 10 7 0,000 0,01390032 0,04872093 ! adenohypophysis development GO:0021984 11 7 0,000 0,01390032 0,04865113 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01390032 0,04858153 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01390032 0,04851212 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01390032 0,04844292 ! microtubule nucleation GO:0007020 21 7 0,000 0,01390032 0,04837391 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01390032 0,0483051 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01390032 0,04823649 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01390032 0,04816807 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01390032 0,04809984 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01390032 0,04803181 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01390032 0,04796396 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01390032 0,04789631 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01390032 0,04782885 ! galactose metabolic process GO:0006012 13 7 0,000 0,01390032 0,04776158 ! vesicle fusion GO:0006906 20 7 0,000 0,01390032 0,0476945 ! response to dietary excess GO:0002021 8 7 0,000 0,01390032 0,04762761 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01390032 0,04756091 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01390032 0,04749439 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01390032 0,04742805 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01390032 0,04736191 ! organ growth GO:0035265 15 7 0,000 0,01390032 0,04729594 ! nucleoside transport GO:0015858 11 7 0,000 0,01390032 0,04723016 ! nucleoside salvage GO:0043174 11 7 0,000 0,01390032 0,04716456 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01390032 0,04709915 ! male sex determination GO:0030238 15 7 0,000 0,01390032 0,04703391 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01390032 0,04696886 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01390032 0,04690399 ! parturition GO:0007567 16 7 0,000 0,01390032 0,04683929 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01390032 0,04677477 ! rRNA modification GO:0000154 14 7 0,000 0,01390032 0,04671044 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01390032 0,04664627 ! spindle checkpoint GO:0031577 16 7 0,000 0,01390032 0,04658229 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01390032 0,04651847 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01390032 0,04645484 ! monocyte differentiation GO:0030224 16 7 0,000 0,01390032 0,04639137 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01390032 0,04632808 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01390032 0,04626497 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01390032 0,04620202 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01390032 0,04613925 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01390032 0,04607664 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01390032 0,04601421 ! fibrinolysis GO:0042730 11 7 0,000 0,01390032 0,04595194 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01390032 0,04588985 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01390032 0,04582792 ! eating behavior GO:0042755 8 7 0,000 0,01390032 0,04576615 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01390032 0,04570456 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01390032 0,04564313 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01390032 0,04558186 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01390032 0,04552076 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01390032 0,04545982 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01390032 0,04539905 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01390032 0,04533843 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01390032 0,04527798 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01390032 0,04521769 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01390032 0,04515756 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01390032 0,04509759 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01390032 0,04503778 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01390032 0,04497813 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01390032 0,04491863 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01390032 0,04485929 ! histone ubiquitination GO:0016574 9 7 0,000 0,01390032 0,04480011 ! regulation of meiosis GO:0040020 12 7 0,000 0,01390032 0,04474109 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01390032 0,04468222 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01390032 0,0446235 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01390032 0,04456494 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01390032 0,04450654 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01390032 0,04444828 ! transcription termination GO:0006353 14 7 0,000 0,01390032 0,04439018 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01390032 0,04433223 ! anaphase GO:0051322 18 7 0,000 0,01390032 0,04427443 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01390032 0,04421678 ! axonal fasciculation GO:0007413 19 7 0,000 0,01390032 0,04415928 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01390032 0,04410193 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01390032 0,04404473 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01390032 0,04398768 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01390032 0,04393077 ! diuresis GO:0030146 12 7 0,000 0,01390032 0,04387401 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01390032 0,0438174 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01390032 0,04376094 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01390032 0,04370462 ! antibiotic transport GO:0042891 9 7 0,000 0,01390032 0,04364844 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01390032 0,04359241 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01390032 0,04353652 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01390032 0,04348078 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01390032 0,04342517 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01390032 0,04336971 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01390032 0,0433144 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01390032 0,04325922 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01390032 0,04320418 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01390032 0,04314928 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01390032 0,04309453 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01390032 0,04303991 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01390032 0,04298543 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01390032 0,04293108 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01390032 0,04287688 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01390032 0,04282281 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01390032 0,04276887 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01390032 0,04271508 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01390032 0,04266141 ! muscle adaptation GO:0043500 13 7 0,000 0,01390032 0,04260789 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01390032 0,04255449 ! retina homeostasis GO:0001895 12 7 0,000 0,01390032 0,04250123 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01390032 0,04244811 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01390032 0,04239511 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01390032 0,04234225 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01390032 0,04228952 ! ossification GO:0001503 205 91 1,000 0,01436635 0,04365297 ! bone development GO:0060348 206 92 1,000 0,01466683 0,04451065 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,01466683 0,04445543 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01587047 0,04804406 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01587047 0,0479846 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01587047 0,04792528 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01587047 0,04786611 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01587047 0,04780709 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01587047 0,04774822 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01587047 0,04768949 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01587047 0,0476309 ! male meiosis GO:0007140 9 8 0,000 0,01587047 0,04757246 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01587047 0,04751416 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01587047 0,047456 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01587047 0,04739799 ! meiotic prophase I GO:0007128 14 8 0,000 0,01587047 0,04734011 ! response to zinc ion GO:0010043 12 8 0,000 0,01587047 0,04728238 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01587047 0,04722479 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01587047 0,04716734 ! oligopeptide transport GO:0006857 16 8 0,000 0,01587047 0,04711003 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01587047 0,04705286 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01587047 0,04699582 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01587047 0,04693893 ! signal peptide processing GO:0006465 12 8 0,000 0,01587047 0,04688217 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01587047 0,04682555 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01587047 0,04676906 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01587047 0,04671271 ! succinate metabolic process GO:0006105 17 8 0,000 0,01587047 0,0466565 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01587047 0,04660042 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01587047 0,04654448 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01587047 0,04648867 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01587047 0,046433 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01587047 0,04637746 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01587047 0,04632205 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01587047 0,04626677 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01587047 0,04621162 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01587047 0,04615661 ! reflex GO:0060004 17 8 0,000 0,01587047 0,04610173 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01587047 0,04604697 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01587047 0,04599235 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01587047 0,04593786 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01587047 0,04588349 ! pigment granule organization GO:0048753 17 8 0,000 0,01587047 0,04582926 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01587047 0,04577515 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01587047 0,04572117 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01587047 0,04566732 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01587047 0,04561359 ! histidine catabolic process GO:0006548 10 8 0,000 0,01587047 0,04555999 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01587047 0,04550652 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01587047 0,04545317 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01587047 0,04539994 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01587047 0,04534685 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01587047 0,04529387 ! melanin metabolic process GO:0006582 17 8 0,000 0,01587047 0,04524102 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01587047 0,04518829 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01587047 0,04513568 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01587047 0,0450832 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01587047 0,04503084 ! macrophage activation GO:0042116 13 8 0,000 0,01587047 0,0449786 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01587047 0,04492648 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01587047 0,04487448 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01587047 0,0448226 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01587047 0,04477085 ! purine salvage GO:0043101 12 8 0,000 0,01587047 0,04471921 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01587047 0,04466769 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01587047 0,04461629 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01587047 0,044565 ! osteoblast development GO:0002076 17 8 0,000 0,01587047 0,04451384 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01587047 0,04446279 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01587047 0,04441186 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01587047 0,04436104 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01587047 0,04431035 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01587047 0,04425976 ! response to UV-B GO:0010224 17 8 0,000 0,01587047 0,0442093 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01587047 0,04415894 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01587047 0,04410871 ! intermediate filament organization GO:0045109 12 8 0,000 0,01587047 0,04405858 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01587047 0,04400857 ! cellular extravasation GO:0045123 13 8 0,000 0,01587047 0,04395868 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01587047 0,04390889 ! response to antibiotic GO:0046677 11 8 0,000 0,01587047 0,04385922 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01587047 0,04380966 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01587047 0,04376022 ! DNA topological change GO:0006265 12 8 0,000 0,01587047 0,04371088 ! response to tropane GO:0014073 15 8 0,000 0,01587047 0,04366166 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01587047 0,04361255 ! melanosome transport GO:0032402 13 8 0,000 0,01587047 0,04356354 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01587047 0,04351465 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01587047 0,04346587 ! mast cell activation GO:0045576 14 8 0,000 0,01587047 0,04341719 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01587047 0,04336863 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01587047 0,04332017 ! gas homeostasis GO:0033483 14 8 0,000 0,01587047 0,04327182 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01587047 0,04322358 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01587047 0,04317545 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01587047 0,04312742 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01587047 0,0430795 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01587047 0,04303169 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01587047 0,04298398 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01587047 0,04293638 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01587047 0,04288889 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01587047 0,04284149 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01587047 0,04279421 ! response to tumor cell GO:0002347 16 8 0,000 0,01587047 0,04274703 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01587047 0,04269995 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01587047 0,04265297 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01587047 0,0426061 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01587047 0,04255933 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01587047 0,04251267 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01587047 0,0424661 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01587047 0,04241964 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01587047 0,04237328 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01587047 0,04232702 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01587047 0,04228086 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01587047 0,04223481 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01587047 0,04218885 ! adult feeding behavior GO:0008343 10 8 0,000 0,01587047 0,04214299 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01587047 0,04209723 ! ATP catabolic process GO:0006200 11 8 0,000 0,01587047 0,04205158 ! blastocyst growth GO:0001832 19 8 0,000 0,01587047 0,04200602 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01587047 0,04196056 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01587047 0,04191519 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01587047 0,04186993 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01587047 0,04182476 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01587047 0,04177969 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01587047 0,04173472 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01587047 0,04168984 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01587047 0,04164506 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01587047 0,04160038 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01587047 0,04155579 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01587047 0,0415113 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01587047 0,0414669 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01587047 0,0414226 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01587047 0,04137839 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01587047 0,04133428 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01587047 0,04129026 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01587047 0,04124633 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01587047 0,0412025 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01587047 0,04115876 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01587047 0,04111511 ! regulation of protein localization GO:0032880 188 97 1,000 0,0162097 0,04194947 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,01716735 0,04438077 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,01716735 0,04433386 ! hormone metabolic process GO:0042445 171 100 1,000 0,01716735 0,04428704 ! axon extension GO:0048675 16 9 0,000 0,01783673 0,04596534 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01783673 0,0459169 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01783673 0,04586857 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01783673 0,04582033 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01783673 0,0457722 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01783673 0,04572417 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01783673 0,04567625 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01783673 0,04562842 ! reproductive behavior GO:0019098 22 9 0,000 0,01783673 0,04558069 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01783673 0,04553306 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01783673 0,04548553 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01783673 0,0454381 ! UTP metabolic process GO:0046051 10 9 0,000 0,01783673 0,04539077 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01783673 0,04534354 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01783673 0,0452964 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01783673 0,04524937 ! artery development GO:0060840 25 9 0,000 0,01783673 0,04520243 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01783673 0,04515558 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01783673 0,04510884 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01783673 0,04506219 ! equilibrioception GO:0050957 20 9 0,000 0,01783673 0,04501564 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01783673 0,04496918 ! chemosensory behavior GO:0007635 21 9 0,000 0,01783673 0,04492282 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01783673 0,04487656 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01783673 0,04483039 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01783673 0,04478432 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01783673 0,04473834 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01783673 0,04469245 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01783673 0,04464666 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01783673 0,04460096 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01783673 0,04455536 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01783673 0,04450985 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01783673 0,04446443 ! protein targeting to ER GO:0045047 25 9 0,000 0,01783673 0,0444191 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01783673 0,04437387 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01783673 0,04432873 ! T cell selection GO:0045058 27 9 0,000 0,01783673 0,04428368 ! glycine catabolic process GO:0006546 15 9 0,000 0,01783673 0,04423872 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01783673 0,04419385 ! endosome organization GO:0007032 20 9 0,000 0,01783673 0,04414908 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01783673 0,04410439 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01783673 0,0440598 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01783673 0,04401529 ! mannose metabolic process GO:0006013 13 9 0,000 0,01783673 0,04397088 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01783673 0,04392655 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01783673 0,04388231 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01783673 0,04383817 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01783673 0,04379411 ! receptor clustering GO:0043113 20 9 0,000 0,01783673 0,04375014 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01783673 0,04370626 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01783673 0,04366246 ! retinol metabolic process GO:0042572 20 9 0,000 0,01783673 0,04361876 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01783673 0,04357514 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01783673 0,04353161 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01783673 0,04348816 ! macrophage differentiation GO:0030225 15 9 0,000 0,01783673 0,0434448 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01783673 0,04340153 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01783673 0,04335835 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01783673 0,04331525 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01783673 0,04327223 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01783673 0,0432293 ! response to amine stimulus GO:0014075 13 9 0,000 0,01783673 0,04318646 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01783673 0,0431437 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01783673 0,04310103 ! erythrocyte development GO:0048821 17 9 0,000 0,01783673 0,04305844 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01783673 0,04301593 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01783673 0,04297351 ! renal water homeostasis GO:0003091 15 9 0,000 0,01783673 0,04293117 ! postreplication repair GO:0006301 25 9 0,000 0,01783673 0,04288892 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01783673 0,04284674 ! icosanoid secretion GO:0032309 15 9 0,000 0,01783673 0,04280465 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01783673 0,04276265 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01783673 0,04272072 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01783673 0,04267888 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01783673 0,04263712 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01783673 0,04259544 ! sterol catabolic process GO:0016127 14 9 0,000 0,01783673 0,04255385 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01783673 0,04251233 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01783673 0,0424709 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01783673 0,04242954 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01783673 0,04238827 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01783673 0,04234707 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01783673 0,04230596 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01783673 0,04226493 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01783673 0,04222397 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01783673 0,0421831 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01783673 0,0421423 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01783673 0,04210158 ! purine base metabolic process GO:0006144 25 9 0,000 0,01783673 0,04206094 ! pigment granule transport GO:0051904 17 9 0,000 0,01783673 0,04202038 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01783673 0,0419799 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01783673 0,0419395 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01783673 0,04189917 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01783673 0,04185892 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01783673 0,04181875 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01783673 0,04177866 ! mitochondrion localization GO:0051646 18 9 0,000 0,01783673 0,04173864 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01979912 0,04628637 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01979912 0,04624212 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01979912 0,04619796 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01979912 0,04615388 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01979912 0,04610988 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01979912 0,04606596 ! associative learning GO:0008306 21 10 0,000 0,01979912 0,04602213 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01979912 0,04597839 ! phosphate transport GO:0006817 24 10 0,000 0,01979912 0,04593472 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01979912 0,04589114 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01979912 0,04584764 ! CTP metabolic process GO:0046036 11 10 0,000 0,01979912 0,04580423 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01979912 0,04576089 ! GTP metabolic process GO:0046039 11 10 0,000 0,01979912 0,04571764 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01979912 0,04567447 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01979912 0,04563138 ! social behavior GO:0035176 29 10 0,000 0,01979912 0,04558837 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01979912 0,04554544 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01979912 0,0455026 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01979912 0,04545983 ! androgen metabolic process GO:0008209 17 10 0,000 0,01979912 0,04541715 ! phospholipid efflux GO:0033700 19 10 0,000 0,01979912 0,04537454 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01979912 0,04533202 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01979912 0,04528957 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01979912 0,0452472 ! lung alveolus development GO:0048286 26 10 0,000 0,01979912 0,04520492 ! pathogenesis GO:0009405 17 10 0,000 0,01979912 0,04516271 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01979912 0,04512058 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01979912 0,04507853 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01979912 0,04503656 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01979912 0,04499466 ! endoderm development GO:0007492 18 10 0,000 0,01979912 0,04495285 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01979912 0,04491111 ! arginine catabolic process GO:0006527 17 10 0,000 0,01979912 0,04486944 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01979912 0,04482786 ! proline metabolic process GO:0006560 13 10 0,000 0,01979912 0,04478635 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01979912 0,04474492 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01979912 0,04470357 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01979912 0,04466229 ! V(D)J recombination GO:0033151 34 10 0,000 0,01979912 0,04462109 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01979912 0,04457996 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01979912 0,04453891 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01979912 0,04449794 ! B cell proliferation GO:0042100 19 10 0,000 0,01979912 0,04445704 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01979912 0,04441622 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01979912 0,04437547 ! multicellular organism growth GO:0035264 19 10 0,000 0,01979912 0,0443348 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01979912 0,0442942 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01979912 0,04425367 ! ruffle organization GO:0031529 17 10 0,000 0,01979912 0,04421322 ! epithelial cell development GO:0002064 21 10 0,000 0,01979912 0,04417284 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01979912 0,04413254 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01979912 0,04409231 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01979912 0,04405215 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01979912 0,04401207 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01979912 0,04397206 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01979912 0,04393212 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01979912 0,04389225 ! motor axon guidance GO:0008045 22 10 0,000 0,01979912 0,04385246 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01979912 0,04381274 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01979912 0,04377309 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01979912 0,04373351 ! brain morphogenesis GO:0048854 23 10 0,000 0,01979912 0,043694 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01979912 0,04365457 ! segment specification GO:0007379 15 10 0,000 0,01979912 0,0436152 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01979912 0,04357591 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01979912 0,04353669 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01979912 0,04349754 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01979912 0,04345846 ! response to dsRNA GO:0043331 23 10 0,000 0,01979912 0,04341944 ! DNA ligation GO:0006266 18 10 0,000 0,01979912 0,0433805 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01979912 0,04334163 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01979912 0,04330283 ! melanosome localization GO:0032400 16 10 0,000 0,01979912 0,0432641 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01979912 0,04322543 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01979912 0,04318684 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01979912 0,04314832 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01979912 0,04310986 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01979912 0,04307147 ! induction of an organ GO:0001759 17 10 0,000 0,01979912 0,04303315 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01979912 0,0429949 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01979912 0,04295672 ! protein sumoylation GO:0016925 17 10 0,000 0,01979912 0,0429186 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01979912 0,04288055 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01979912 0,04284257 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01979912 0,04280466 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01979912 0,04276681 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01979912 0,04272903 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01979912 0,04269132 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01979912 0,04265367 ! midbrain development GO:0030901 14 10 0,000 0,01979912 0,04261609 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01979912 0,04257858 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01979912 0,04254113 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01979912 0,04250374 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01979912 0,04246643 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01979912 0,04242918 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01979912 0,04239199 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01979912 0,04235487 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01979912 0,04231781 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01979912 0,04228082 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01979912 0,0422439 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01979912 0,04220703 ! blastocyst formation GO:0001825 18 10 0,000 0,01979912 0,04217024 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01979912 0,0421335 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01979912 0,04209683 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01979912 0,04206023 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01979912 0,04202369 ! response to nicotine GO:0035094 20 10 0,000 0,01979912 0,04198721 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01979912 0,04195079 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01979912 0,04191444 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02175765 0,04602073 ! respiratory burst GO:0045730 17 11 0,000 0,02175765 0,04598092 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02175765 0,04594118 ! neuron fate specification GO:0048665 18 11 0,000 0,02175765 0,0459015 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02175765 0,0458619 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02175765 0,04582236 ! thyroid gland development GO:0030878 26 11 0,000 0,02175765 0,04578289 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,02175765 0,04574349 ! synapsis GO:0007129 14 11 0,000 0,02175765 0,04570416 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02175765 0,0456649 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02175765 0,0456257 ! response to pain GO:0048265 27 11 0,000 0,02175765 0,04558657 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02175765 0,04554751 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02175765 0,04550851 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02175765 0,04546958 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02175765 0,04543072 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02175765 0,04539192 ! bone resorption GO:0045453 16 11 0,000 0,02175765 0,04535319 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02175765 0,04531453 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02175765 0,04527593 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02175765 0,0452374 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02175765 0,04519893 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02175765 0,04516053 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02175765 0,04512219 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02175765 0,04508392 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02175765 0,04504571 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02175765 0,04500757 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02175765 0,04496949 ! UV protection GO:0009650 20 11 0,000 0,02175765 0,04493148 ! adult heart development GO:0007512 16 11 0,000 0,02175765 0,04489353 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02175765 0,04485565 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02175765 0,04481783 ! macroautophagy GO:0016236 19 11 0,000 0,02175765 0,04478007 ! temperature homeostasis GO:0001659 18 11 0,000 0,02175765 0,04474237 ! behavioral fear response GO:0001662 27 11 0,000 0,02175765 0,04470474 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02175765 0,04466718 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02175765 0,04462967 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02175765 0,04459223 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02175765 0,04455485 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02175765 0,04451754 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02175765 0,04448029 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02175765 0,04444309 ! regulation of organ growth GO:0046620 14 11 0,000 0,02175765 0,04440597 ! pigment granule localization GO:0051875 20 11 0,000 0,02175765 0,0443689 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02175765 0,04433189 ! vasoconstriction GO:0042310 20 11 0,000 0,02175765 0,04429495 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02175765 0,04425807 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02175765 0,04422125 ! embryonic axis specification GO:0000578 19 11 0,000 0,02175765 0,04418449 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02175765 0,04414779 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02175765 0,04411115 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02175765 0,04407458 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02175765 0,04403806 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02175765 0,04400161 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02175765 0,04396521 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02175765 0,04392888 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02175765 0,0438926 ! prophase GO:0051324 17 11 0,000 0,02175765 0,04385639 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02175765 0,04382023 ! nucleosome positioning GO:0016584 15 11 0,000 0,02175765 0,04378414 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02175765 0,0437481 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02175765 0,04371212 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02175765 0,0436762 ! apical protein localization GO:0045176 18 11 0,000 0,02175765 0,04364035 ! acid secretion GO:0046717 20 11 0,000 0,02175765 0,04360455 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02175765 0,0435688 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02175765 0,04353312 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02175765 0,0434975 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02175765 0,04346193 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02175765 0,04342642 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02175765 0,04339097 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02175765 0,04335558 ! cholesterol efflux GO:0033344 21 11 0,000 0,02175765 0,04332024 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02175765 0,04328497 ! oocyte development GO:0048599 20 11 0,000 0,02175765 0,04324975 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02175765 0,04321459 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02175765 0,04317948 ! embryonic gut development GO:0048566 19 11 0,000 0,02175765 0,04314443 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02175765 0,04310944 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02175765 0,04307451 ! activation of innate immune response GO:0002218 16 11 0,000 0,02175765 0,04303963 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02175765 0,04300481 ! lysogeny GO:0030069 22 11 0,000 0,02175765 0,04297004 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02175765 0,04293533 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02175765 0,04290068 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02175765 0,04286608 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02175765 0,04283154 ! nucleus localization GO:0051647 22 11 0,000 0,02175765 0,04279705 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02371232 0,04660434 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02371232 0,04656688 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02371232 0,04652947 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02371232 0,04649213 ! virus-host interaction GO:0019048 30 12 0,000 0,02371232 0,04645485 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02371232 0,04641762 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02371232 0,04638046 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02371232 0,04634336 ! protein complex disassembly GO:0043241 28 12 0,000 0,02371232 0,04630631 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02371232 0,04626932 ! hippocampus development GO:0021766 29 12 0,000 0,02371232 0,0462324 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02371232 0,04619553 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02371232 0,04615872 ! T cell proliferation GO:0042098 32 12 0,000 0,02371232 0,04612197 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02371232 0,04608528 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02371232 0,04604864 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02371232 0,04601207 ! drug transport GO:0015893 16 12 0,000 0,02371232 0,04597555 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02371232 0,04593909 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02371232 0,04590269 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02371232 0,04586635 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02371232 0,04583006 ! focal adhesion formation GO:0048041 37 12 0,000 0,02371232 0,04579383 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02371232 0,04575766 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02371232 0,04572154 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02371232 0,04568548 ! lipid digestion GO:0044241 21 12 0,000 0,02371232 0,04564948 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02371232 0,04561354 ! entry into host cell GO:0030260 34 12 0,000 0,02371232 0,04557765 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02371232 0,04554182 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02371232 0,04550604 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02371232 0,04547032 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02371232 0,04543466 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02371232 0,04539905 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02371232 0,0453635 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02371232 0,04532801 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02371232 0,04529257 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02371232 0,04525718 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02371232 0,04522185 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02371232 0,04518658 ! cranial nerve development GO:0021545 23 12 0,000 0,02371232 0,04515136 ! fucose catabolic process GO:0019317 25 12 0,000 0,02371232 0,04511619 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02371232 0,04508108 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02371232 0,04504603 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02371232 0,04501103 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02371232 0,04497608 ! zymogen activation GO:0031638 18 12 0,000 0,02371232 0,04494119 ! T cell homeostasis GO:0043029 28 12 0,000 0,02371232 0,04490635 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02371232 0,04487157 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02371232 0,04483684 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02371232 0,04480216 ! oocyte differentiation GO:0009994 21 12 0,000 0,02371232 0,04476754 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02371232 0,04473297 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02371232 0,04469845 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02371232 0,04466399 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02371232 0,04462958 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02371232 0,04459522 ! defense response to fungus GO:0050832 15 12 0,000 0,02371232 0,04456092 ! developmental induction GO:0031128 22 12 0,000 0,02371232 0,04452667 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02371232 0,04449247 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02371232 0,04445832 ! response to cold GO:0009409 17 12 0,000 0,02371232 0,04442423 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02371232 0,04439019 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02371232 0,0443562 ! localization within membrane GO:0051668 26 12 0,000 0,02371232 0,04432226 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02566314 0,04793199 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02566314 0,04789537 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02566314 0,04785881 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02566314 0,0478223 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02566314 0,04778585 ! peroxisomal transport GO:0043574 28 13 0,000 0,02566314 0,04774946 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02566314 0,04771312 ! cartilage condensation GO:0001502 22 13 0,000 0,02566314 0,04767684 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02566314 0,04764061 ! organelle fusion GO:0048284 36 13 0,000 0,02566314 0,04760443 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02566314 0,04756832 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02566314 0,04753225 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02566314 0,04749624 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02566314 0,04746029 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02566314 0,04742439 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02566314 0,04738854 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02566314 0,04735275 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02566314 0,04731701 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02566314 0,04728133 ! methionine metabolic process GO:0006555 31 13 0,000 0,02566314 0,0472457 ! plasma membrane organization GO:0007009 27 13 0,000 0,02566314 0,04721012 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02566314 0,0471746 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02566314 0,04713913 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02566314 0,04710371 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02566314 0,04706835 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02566314 0,04703304 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02566314 0,04699778 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02566314 0,04696258 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02566314 0,04692742 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02566314 0,04689233 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02566314 0,04685728 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02566314 0,04682228 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02566314 0,04678734 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02566314 0,04675245 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02566314 0,04671762 ! protein homotetramerization GO:0051289 24 13 0,000 0,02566314 0,04668283 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02566314 0,04664809 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02566314 0,04661341 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02566314 0,04657878 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02566314 0,0465442 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02566314 0,04650967 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02566314 0,0464752 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,02566314 0,04644077 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02566314 0,04640639 ! histone methylation GO:0016571 29 13 0,000 0,02566314 0,04637207 ! chromatin silencing GO:0006342 29 13 0,000 0,02566314 0,0463378 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02566314 0,04630357 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02566314 0,0462694 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02566314 0,04623528 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02566314 0,04620121 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02566314 0,04616719 ! spleen development GO:0048536 24 13 0,000 0,02566314 0,04613322 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02566314 0,04609929 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02566314 0,04606542 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02566314 0,0460316 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02566314 0,04599783 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02566314 0,04596411 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02566314 0,04593043 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02566314 0,04589681 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02566314 0,04586323 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02566314 0,04582971 ! insulin secretion GO:0030073 24 13 0,000 0,02566314 0,04579623 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02566314 0,0457628 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02566314 0,04572942 ! acrosome reaction GO:0007340 19 13 0,000 0,02566314 0,04569609 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02566314 0,04566281 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02566314 0,04562958 ! rRNA transcription GO:0009303 28 14 0,000 0,02761011 0,04905563 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02761011 0,04901998 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02761011 0,04898438 ! water transport GO:0006833 21 14 0,000 0,02761011 0,04894884 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02761011 0,04891334 ! non-recombinational repair GO:0000726 29 14 0,000 0,02761011 0,0488779 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02761011 0,0488425 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02761011 0,04880716 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02761011 0,04877187 ! lipid localization GO:0010876 32 14 0,000 0,02761011 0,04873663 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02761011 0,04870144 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02761011 0,0486663 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02761011 0,04863122 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02761011 0,04859618 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02761011 0,04856119 ! arginine metabolic process GO:0006525 21 14 0,000 0,02761011 0,04852626 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02761011 0,04849137 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02761011 0,04845653 ! regulation of heart rate GO:0002027 25 14 0,000 0,02761011 0,04842175 ! fear response GO:0042596 34 14 0,000 0,02761011 0,04838701 ! organic alcohol transport GO:0015850 29 14 0,000 0,02761011 0,04835233 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02761011 0,04831769 ! embryo implantation GO:0007566 30 14 0,000 0,02761011 0,0482831 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02761011 0,04824857 ! bone mineralization GO:0030282 18 14 0,000 0,02761011 0,04821408 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02761011 0,04817964 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02761011 0,04814525 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02761011 0,04811091 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02761011 0,04807662 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02761011 0,04804238 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02761011 0,04800818 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02761011 0,04797404 ! ribosome assembly GO:0042255 18 14 0,000 0,02761011 0,04793994 ! cerebellum development GO:0021549 23 14 0,000 0,02761011 0,04790589 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02761011 0,04787189 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02761011 0,04783794 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02761011 0,04780404 ! response to gamma radiation GO:0010332 30 14 0,000 0,02761011 0,04777018 ! NADP metabolic process GO:0006739 24 14 0,000 0,02761011 0,04773637 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02761011 0,04770261 ! oxygen transport GO:0015671 22 14 0,000 0,02761011 0,0476689 ! male genitalia development GO:0030539 26 14 0,000 0,02761011 0,04763524 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02761011 0,04760162 ! regulation of axon extension GO:0030516 43 14 0,000 0,02761011 0,04756805 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02761011 0,04753453 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02761011 0,04750105 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02761011 0,04746763 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02955325 0,05077256 ! lactation GO:0007595 30 15 0,000 0,02955325 0,05073688 ! reproductive cellular process GO:0048610 22 15 0,000 0,02955325 0,05070125 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02955325 0,05066567 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02955325 0,05063014 ! superoxide anion generation GO:0042554 22 15 0,000 0,02955325 0,05059466 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02955325 0,05055923 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02955325 0,05052385 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02955325 0,05048852 ! copper ion transport GO:0006825 22 15 0,000 0,02955325 0,05045324 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02955325 0,050418 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02955325 0,05038282 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02955325 0,05034769 ! sulfate transport GO:0008272 27 15 0,000 0,02955325 0,0503126 ! response to cAMP GO:0051591 25 15 0,000 0,02955325 0,05027756 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02955325 0,05024258 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02955325 0,05020764 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02955325 0,05017275 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02955325 0,0501379 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02955325 0,05010311 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02955325 0,05006836 ! vesicle coating GO:0006901 38 15 0,000 0,02955325 0,05003367 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02955325 0,04999902 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02955325 0,04996442 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02955325 0,04992986 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02955325 0,04989536 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02955325 0,0498609 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02955325 0,04982649 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02955325 0,04979212 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02955325 0,04975781 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02955325 0,04972354 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02955325 0,04968932 ! histone deacetylation GO:0016575 24 15 0,000 0,02955325 0,04965515 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02955325 0,04962102 ! water homeostasis GO:0030104 28 15 0,000 0,02955325 0,04958694 ! cofactor transport GO:0051181 30 15 0,000 0,02955325 0,0495529 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02955325 0,04951892 ! muscle maintenance GO:0046716 26 15 0,000 0,02955325 0,04948498 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02955325 0,04945108 ! intestinal absorption GO:0050892 31 15 0,000 0,02955325 0,04941724 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02955325 0,04938343 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02955325 0,04934968 ! cell killing GO:0001906 32 15 0,000 0,02955325 0,04931597 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02955325 0,04928231 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02955325 0,04924869 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02955325 0,04921512 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02955325 0,04918159 ! actin filament polymerization GO:0030041 27 15 0,000 0,02955325 0,04914812 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02955325 0,04911468 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03149256 0,05230205 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03149256 0,05226652 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03149256 0,05223103 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03149256 0,0521956 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03149256 0,05216021 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03149256 0,05212487 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03149256 0,05208958 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03149256 0,05205434 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03149256 0,05201914 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03149256 0,051984 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03149256 0,0519489 ! startle response GO:0001964 28 16 0,000 0,03149256 0,05191384 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03149256 0,05187884 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03149256 0,05184388 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03149256 0,05180897 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03149256 0,0517741 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03149256 0,05173928 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03149256 0,05170451 ! pituitary gland development GO:0021983 30 16 0,000 0,03149256 0,05166979 ! response to osmotic stress GO:0006970 27 16 0,000 0,03149256 0,05163511 ! lysosomal transport GO:0007041 31 16 0,000 0,03149256 0,05160048 ! fructose metabolic process GO:0006000 25 16 0,000 0,03149256 0,05156589 ! L-amino acid transport GO:0015807 33 16 0,000 0,03149256 0,05153136 ! stem cell development GO:0048864 46 16 0,000 0,03149256 0,05149686 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03149256 0,05146242 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,03149256 0,05142802 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03149256 0,05139366 ! axon cargo transport GO:0008088 46 16 0,000 0,03149256 0,05135935 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03149256 0,05132509 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03149256 0,05129088 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03149256 0,0512567 ! DNA replication initiation GO:0006270 28 16 0,000 0,03149256 0,05122258 ! neuron recognition GO:0008038 40 16 0,000 0,03149256 0,0511885 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03149256 0,05115446 ! tissue regeneration GO:0042246 27 16 0,000 0,03149256 0,05112047 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03149256 0,05108653 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03149256 0,05105263 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03149256 0,05101878 ! biomineral formation GO:0031214 22 16 0,000 0,03149256 0,05098497 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03149256 0,0509512 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03149256 0,05091748 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03149256 0,05088381 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03149256 0,05085017 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03149256 0,05081659 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03149256 0,05078305 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03149256 0,05074955 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03149256 0,05071609 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,03149256 0,05068268 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03342804 0,05376215 ! metencephalon development GO:0022037 32 17 0,000 0,03342804 0,05372678 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03342804 0,05369146 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03342804 0,05365618 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03342804 0,05362095 ! signal complex assembly GO:0007172 47 17 0,000 0,03342804 0,05358577 ! filopodium assembly GO:0046847 42 17 0,000 0,03342804 0,05355063 ! endothelial cell migration GO:0043542 31 17 0,000 0,03342804 0,05351554 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03342804 0,05348049 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03342804 0,05344549 ! glial cell development GO:0021782 28 17 0,000 0,03342804 0,05341054 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03342804 0,05337563 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03342804 0,05334077 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03342804 0,05330595 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03342804 0,05327118 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03342804 0,05323645 ! myoblast differentiation GO:0045445 50 17 0,000 0,03342804 0,05320177 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03342804 0,05316713 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03342804 0,05313254 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03342804 0,05309799 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03342804 0,05306349 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03342804 0,05302903 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03342804 0,05299462 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03342804 0,05296025 ! NAD metabolic process GO:0019674 33 17 0,000 0,03342804 0,05292593 ! membrane budding GO:0006900 42 17 0,000 0,03342804 0,05289165 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03342804 0,05285742 ! regulation of protein binding GO:0043393 33 17 0,000 0,03342804 0,05282323 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03342804 0,05278908 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03342804 0,05275498 ! genitalia development GO:0048806 32 17 0,000 0,03342804 0,05272092 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03342804 0,05268691 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03342804 0,05265294 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03342804 0,05261902 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03342804 0,05258513 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03342804 0,05255129 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03342804 0,0525175 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03342804 0,05248375 ! gas transport GO:0015669 26 17 0,000 0,03342804 0,05245004 ! organic cation transport GO:0015695 32 17 0,000 0,03342804 0,05241637 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03342804 0,05238275 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03342804 0,05234917 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03342804 0,05231564 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,03535972 0,05530332 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03535972 0,05526794 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03535972 0,0552326 ! limbic system development GO:0021761 40 18 0,000 0,03535972 0,05519731 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03535972 0,05516206 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03535972 0,05512686 ! adult walking behavior GO:0007628 36 18 0,000 0,03535972 0,0550917 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03535972 0,05505659 ! heart looping GO:0001947 34 18 0,000 0,03535972 0,05502152 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03535972 0,0549865 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03535972 0,05495152 ! centrosome cycle GO:0007098 26 18 0,000 0,03535972 0,05491659 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03535972 0,0548817 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03535972 0,05484685 ! glycine metabolic process GO:0006544 30 18 0,000 0,03535972 0,05481205 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03535972 0,05477729 ! response to retinoic acid GO:0032526 31 18 0,000 0,03535972 0,05474258 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03535972 0,05470791 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,03535972 0,05467329 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03535972 0,05463871 ! DNA integration GO:0015074 32 18 0,000 0,03535972 0,05460417 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03535972 0,05456967 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03535972 0,05453522 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03535972 0,05450082 ! neural crest cell migration GO:0001755 41 18 0,000 0,03535972 0,05446645 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03535972 0,05443213 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03535972 0,05439785 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03535972 0,05436362 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03535972 0,05432943 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03535972 0,05429528 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03535972 0,05426118 ! detection of bacterium GO:0016045 22 18 0,000 0,03535972 0,05422711 ! nerve development GO:0021675 34 18 0,000 0,03535972 0,05419309 ! defense response to virus GO:0051607 43 18 0,000 0,03535972 0,05415912 ! microspike assembly GO:0030035 46 18 0,000 0,03535972 0,05412518 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03535972 0,05409129 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03728759 0,05700474 ! positive regulation of translation GO:0045727 31 19 0,000 0,03728759 0,05696909 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03728759 0,05693349 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03728759 0,05689792 ! neuron maturation GO:0042551 46 19 0,000 0,03728759 0,05686241 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03728759 0,05682693 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03728759 0,05679151 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03728759 0,05675612 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03728759 0,05672078 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03728759 0,05668549 ! inositol metabolic process GO:0006020 33 19 0,000 0,03728759 0,05665023 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03728759 0,05661503 ! memory GO:0007613 34 19 0,000 0,03728759 0,05657986 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03728759 0,05654474 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03728759 0,05650966 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03728759 0,05647463 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03728759 0,05643964 ! cerebral cortex development GO:0021987 40 19 0,000 0,03728759 0,05640469 ! response to vitamin A GO:0033189 32 19 0,000 0,03728759 0,05636979 ! heme metabolic process GO:0042168 40 19 0,000 0,03728759 0,05633493 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03728759 0,05630011 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03728759 0,05626533 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03728759 0,0562306 ! response to fungus GO:0009620 26 19 0,000 0,03728759 0,05619591 ! peptide cross-linking GO:0018149 39 19 0,000 0,03728759 0,05616127 ! protein export from nucleus GO:0006611 40 19 0,000 0,03728759 0,05612666 ! heart process GO:0003015 32 19 0,000 0,03728759 0,0560921 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03728759 0,05605759 ! visual learning GO:0008542 38 19 0,000 0,03728759 0,05602311 ! cellular pigmentation GO:0033059 37 19 0,000 0,03728759 0,05598868 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03728759 0,05595429 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03728759 0,05591994 ! vitamin transport GO:0051180 31 19 0,000 0,03728759 0,05588563 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03728759 0,05585136 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03728759 0,05581714 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03728759 0,05578296 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03728759 0,05574882 ! cilium assembly GO:0042384 38 19 0,000 0,03728759 0,05571473 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03728759 0,05568067 ! protein secretion GO:0009306 45 20 0,000 0,03921166 0,05851807 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03921166 0,05848234 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03921166 0,05844666 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03921166 0,05841102 ! skin development GO:0043588 42 20 0,000 0,03921166 0,05837543 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03921166 0,05833988 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03921166 0,05830437 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03921166 0,0582689 ! response to vitamin GO:0033273 36 20 0,000 0,03921166 0,05823348 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03921166 0,0581981 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,03921166 0,05816277 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03921166 0,05812747 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03921166 0,05809222 ! response to alkaloid GO:0043279 38 20 0,000 0,03921166 0,05805702 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03921166 0,05802185 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03921166 0,05798673 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03921166 0,05795165 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03921166 0,05791661 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03921166 0,05788162 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03921166 0,05784667 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,03921166 0,05781176 ! body fluid secretion GO:0007589 33 20 0,000 0,03921166 0,05777689 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03921166 0,05774206 ! peptide secretion GO:0002790 38 20 0,000 0,03921166 0,05770728 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03921166 0,05767253 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,03921166 0,05763783 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03921166 0,05760317 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03921166 0,05756856 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03921166 0,05753398 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03921166 0,05749945 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03921166 0,05746495 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03921166 0,0574305 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03921166 0,05739609 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03921166 0,05736172 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03921166 0,0573274 ! regulation of glucose import GO:0046324 30 20 0,000 0,03921166 0,05729311 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03921166 0,05725886 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03921166 0,05722466 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03921166 0,05719049 ! negative regulation of translation GO:0017148 32 20 0,000 0,03921166 0,05715637 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03921166 0,05712229 ! regulation of cell killing GO:0031341 46 21 0,000 0,04113194 0,05988398 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04113194 0,05984831 ! hormone secretion GO:0046879 39 21 0,000 0,04113194 0,05981269 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04113194 0,05977711 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04113194 0,05974157 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04113194 0,05970607 ! ovarian follicle development GO:0001541 39 21 0,000 0,04113194 0,05967062 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04113194 0,0596352 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,04113194 0,05959983 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04113194 0,0595645 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04113194 0,05952922 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04113194 0,05949397 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04113194 0,05945877 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04113194 0,05942361 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04113194 0,05938849 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04113194 0,05935341 ! sensory perception of pain GO:0019233 33 21 0,000 0,04113194 0,05931837 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04113194 0,05928337 ! diencephalon development GO:0021536 36 21 0,000 0,04113194 0,05924842 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04113194 0,05921351 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04113194 0,05917863 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04113194 0,0591438 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04113194 0,05910901 ! collagen catabolic process GO:0030574 29 21 0,000 0,04113194 0,05907426 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04113194 0,05903955 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04113194 0,05900488 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04113194 0,05897026 ! actin filament-based movement GO:0030048 47 21 0,000 0,04113194 0,05893567 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04113194 0,05890112 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04304843 0,06160944 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04304843 0,06157337 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04304843 0,06153734 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04304843 0,06150135 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04304843 0,06146541 ! microtubule-based transport GO:0010970 59 22 0,000 0,04304843 0,06142951 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04304843 0,06139365 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04304843 0,06135783 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,04304843 0,06132205 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04304843 0,06128631 ! cellular response to starvation GO:0009267 37 22 0,000 0,04304843 0,06125062 ! vacuolar transport GO:0007034 41 22 0,000 0,04304843 0,06121497 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04304843 0,06117936 ! fucose metabolic process GO:0006004 44 22 0,000 0,04304843 0,06114379 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04304843 0,06110826 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04304843 0,06107277 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04304843 0,06103733 ! cell aging GO:0007569 48 22 0,000 0,04304843 0,06100192 ! stem cell differentiation GO:0048863 57 22 0,000 0,04304843 0,06096656 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04304843 0,06093124 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04304843 0,06089596 ! cytolysis GO:0019835 27 22 0,000 0,04304843 0,06086071 ! renal system process GO:0003014 42 22 0,000 0,04304843 0,06082551 ! vasodilation GO:0042311 40 22 0,000 0,04304843 0,06079036 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04304843 0,06075524 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04304843 0,06072016 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04304843 0,06068512 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04304843 0,06065012 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04304843 0,06061517 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04304843 0,06058025 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04304843 0,06054537 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04304843 0,06051054 ! sarcomere organization GO:0045214 32 22 0,000 0,04304843 0,06047574 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,04304843 0,06044099 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04304843 0,06040627 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04304843 0,06037159 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04304843 0,06033696 ! gut development GO:0048565 44 22 0,000 0,04304843 0,06030236 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04304843 0,0602678 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04304843 0,06023328 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04304843 0,06019881 ! protein stabilization GO:0050821 41 22 0,000 0,04304843 0,06016437 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04496115 0,06280165 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04496115 0,06276576 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04496115 0,06272992 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04496115 0,06269411 ! gluconeogenesis GO:0006094 38 23 0,000 0,04496115 0,06265835 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04496115 0,06262263 ! viral genome replication GO:0019079 44 23 0,000 0,04496115 0,06258694 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04496115 0,0625513 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04496115 0,0625157 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04496115 0,06248014 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04496115 0,06244462 ! regeneration GO:0031099 42 23 0,000 0,04496115 0,06240914 ! axis specification GO:0009798 43 23 0,000 0,04496115 0,0623737 ! visual behavior GO:0007632 46 23 0,000 0,04496115 0,0623383 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04496115 0,06230294 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04496115 0,06226762 ! response to ethanol GO:0045471 47 23 0,000 0,04496115 0,06223234 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04496115 0,0621971 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04496115 0,0621619 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04496115 0,06212674 ! peroxisome organization GO:0007031 43 23 0,000 0,04496115 0,06209162 ! lysosome organization GO:0007040 47 23 0,000 0,04496115 0,06205654 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04496115 0,0620215 ! vesicle targeting GO:0006903 49 23 0,000 0,04496115 0,0619865 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04496115 0,06195154 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04496115 0,06191662 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04496115 0,06188174 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04496115 0,06184689 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04496115 0,06181209 ! DNA modification GO:0006304 36 23 0,000 0,04496115 0,06177733 ! fatty acid transport GO:0015908 47 23 0,000 0,04496115 0,0617426 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04496115 0,06170791 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04496115 0,06167326 ! hormone transport GO:0009914 41 23 0,000 0,04496115 0,06163866 ! cell-cell recognition GO:0009988 28 23 0,000 0,04496115 0,06160409 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04496115 0,06156955 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04496115 0,06153506 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04496115 0,06150061 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0468701 0,06407591 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0468701 0,06404007 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0468701 0,06400427 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0468701 0,06396852 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0468701 0,0639328 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0468701 0,06389712 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0468701 0,06386149 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0468701 0,06382589 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0468701 0,06379033 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0468701 0,06375481 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,0468701 0,06371934 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0468701 0,0636839 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0468701 0,0636485 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0468701 0,06361314 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0468701 0,06357782 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0468701 0,06354253 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0468701 0,06350729 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0468701 0,06347209 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0468701 0,06343692 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0468701 0,0634018 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,0468701 0,06336671 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0468701 0,06333166 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0468701 0,06329665 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0468701 0,06326168 ! membrane depolarization GO:0051899 45 24 0,000 0,0468701 0,06322675 ! pallium development GO:0021543 56 24 0,000 0,0468701 0,06319186 ! oogenesis GO:0048477 44 24 0,000 0,0468701 0,063157 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0468701 0,06312219 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0468701 0,06308741 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0468701 0,06305267 ! platelet activation GO:0030168 41 24 0,000 0,0468701 0,06301797 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0468701 0,0629833 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0468701 0,06294868 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0468701 0,06291409 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0468701 0,06287954 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0468701 0,06284503 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0468701 0,06281056 ! regulation of amine transport GO:0051952 41 24 0,000 0,0468701 0,06277612 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,04877528 0,06529206 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,04877528 0,06525631 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,04877528 0,06522059 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,04877528 0,06518491 ! leukocyte adhesion GO:0007159 55 25 0,000 0,04877528 0,06514927 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,04877528 0,06511367 ! phototransduction GO:0007602 37 25 0,000 0,04877528 0,06507811 ! keratinization GO:0031424 37 25 0,000 0,04877528 0,06504259 ! vasculogenesis GO:0001570 49 25 0,000 0,04877528 0,0650071 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,04877528 0,06497166 ! vacuole organization GO:0007033 49 25 0,000 0,04877528 0,06493625 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,04877528 0,06490088 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,04877528 0,06486555 ! receptor metabolic process GO:0043112 53 25 0,000 0,04877528 0,06483026 ! chromosome condensation GO:0030261 48 25 0,000 0,04877528 0,06479501 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,04877528 0,06475979 ! regulation of behavior GO:0050795 48 25 0,000 0,04877528 0,06472461 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,04877528 0,06468948 ! interaction with host GO:0051701 66 25 0,000 0,04877528 0,06465438 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,04877528 0,06461931 ! immunoglobulin production GO:0002377 62 25 0,000 0,04877528 0,06458429 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,04877528 0,0645493 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,04877528 0,06451436 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,04877528 0,06447945 ! liver development GO:0001889 55 25 0,000 0,04877528 0,06444457 ! protein tetramerization GO:0051262 57 25 0,000 0,04877528 0,06440974 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05067671 0,0668845 ! myelination GO:0042552 50 26 0,000 0,05067671 0,06684839 ! initiation of viral infection GO:0019059 60 26 0,000 0,05067671 0,06681231 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05067671 0,06677628 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05067671 0,06674028 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05067671 0,06670432 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05067671 0,0666684 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05067671 0,06663252 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05067671 0,06659667 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05067671 0,06656087 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,05067671 0,0665251 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05067671 0,06648937 ! digestive system process GO:0022600 49 26 0,000 0,05067671 0,06645368 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05067671 0,06641803 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,05067671 0,06638242 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,05067671 0,06634685 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05067671 0,06631131 ! neural crest cell development GO:0014032 59 26 0,000 0,05067671 0,06627581 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05067671 0,06624035 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05067671 0,06620493 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05067671 0,06616954 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05067671 0,0661342 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05067671 0,06609889 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,05067671 0,06606361 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05067671 0,06602838 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05067671 0,06599318 ! blastocyst development GO:0001824 50 26 0,000 0,05067671 0,06595803 ! telomere organization GO:0032200 46 26 0,000 0,05067671 0,0659229 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05067671 0,06588782 ! neural tube closure GO:0001843 58 26 0,000 0,05067671 0,06585277 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05067671 0,06581776 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05067671 0,06578279 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0525744 0,06820991 ! embryonic pattern specification GO:0009880 49 27 0,000 0,0525744 0,0681737 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,0525744 0,06813754 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,0525744 0,06810141 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0525744 0,06806532 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0525744 0,06802927 ! iron ion transport GO:0006826 65 27 0,000 0,0525744 0,06799325 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0525744 0,06795728 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0525744 0,06792134 ! tube lumen formation GO:0035148 59 27 0,000 0,0525744 0,06788544 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,0525744 0,06784958 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,0525744 0,06781376 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,0525744 0,06777797 ! response to starvation GO:0042594 47 27 0,000 0,0525744 0,06774222 ! response to toxin GO:0009636 49 27 0,000 0,0525744 0,06770651 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,0525744 0,06767084 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,0525744 0,06763521 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,0525744 0,06759961 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0525744 0,06756405 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0525744 0,06752853 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,0525744 0,06749304 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,05446834 0,06988769 ! neuron fate commitment GO:0048663 52 28 0,000 0,05446834 0,069851 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,05446834 0,06981436 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05446834 0,06977775 ! vesicle docking GO:0048278 55 28 0,000 0,05446834 0,06974118 ! circadian rhythm GO:0007623 56 28 0,000 0,05446834 0,06970464 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05446834 0,06966815 ! fat cell differentiation GO:0045444 57 28 0,000 0,05446834 0,06963169 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05446834 0,06959527 ! sperm motility GO:0030317 37 28 0,000 0,05446834 0,06955889 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05446834 0,06952255 ! base-excision repair GO:0006284 41 28 0,000 0,05446834 0,06948625 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05446834 0,06944998 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05446834 0,06941375 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05446834 0,06937756 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05446834 0,06934141 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05446834 0,06930529 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05446834 0,06926922 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05446834 0,06923318 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05446834 0,06919717 ! lipid oxidation GO:0034440 48 28 0,000 0,05446834 0,06916121 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05446834 0,06912528 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05635855 0,07148699 ! translational initiation GO:0006413 66 29 0,000 0,05635855 0,0714499 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05635855 0,07141284 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05635855 0,07137582 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,05635855 0,07133883 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05635855 0,07130189 ! primary neural tube formation GO:0014020 61 29 0,000 0,05635855 0,07126498 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05635855 0,07122812 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05635855 0,07119129 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05635855 0,0711545 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,05635855 0,07111774 ! synaptogenesis GO:0007416 46 29 0,000 0,05635855 0,07108103 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05635855 0,07104435 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05635855 0,07100771 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05635855 0,07097111 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05635855 0,07093454 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,05824504 0,07327118 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,05824504 0,07323347 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,05824504 0,0731958 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,05824504 0,07315817 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,05824504 0,07312057 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,05824504 0,07308302 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,05824504 0,0730455 ! acute-phase response GO:0006953 50 30 0,000 0,05824504 0,07300802 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,05824504 0,07297058 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,05824504 0,07293318 ! myofibril assembly GO:0030239 50 30 0,000 0,05824504 0,07289582 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,05824504 0,07285849 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,05824504 0,0728212 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,05824504 0,07278396 ! cell fate determination GO:0001709 64 30 0,000 0,05824504 0,07274675 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,05824504 0,07270957 ! phospholipid transport GO:0015914 65 30 0,000 0,05824504 0,07267244 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,05824504 0,07263534 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,05824504 0,07259828 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,05824504 0,07256126 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,05824504 0,07252428 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,05824504 0,07248733 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,05824504 0,07245042 ! regulation of coagulation GO:0050818 52 30 0,000 0,05824504 0,07241355 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06012781 0,07471629 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06012781 0,07467831 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06012781 0,07464036 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06012781 0,07460246 ! cell junction assembly GO:0034329 85 31 0,000 0,06012781 0,07456459 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06012781 0,07452676 ! ovulation cycle process GO:0022602 55 31 0,000 0,06012781 0,07448896 ! peptide transport GO:0015833 60 31 0,000 0,06012781 0,07445121 ! male gonad development GO:0008584 56 31 0,000 0,06012781 0,07441349 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06012781 0,07437582 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06012781 0,07433818 ! detection of light stimulus GO:0009583 44 31 0,000 0,06012781 0,07430057 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,06012781 0,07426301 ! natural killer cell activation GO:0030101 50 31 0,000 0,06012781 0,07422548 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06012781 0,074188 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06012781 0,07415055 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06012781 0,07411314 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06012781 0,07407576 ! eye morphogenesis GO:0048592 65 31 0,000 0,06012781 0,07403842 ! response to heat GO:0009408 54 31 0,000 0,06012781 0,07400113 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06012781 0,07396386 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06200686 0,07623692 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06200686 0,07619858 ! collagen metabolic process GO:0032963 49 32 0,000 0,06200686 0,07616027 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06200686 0,07612199 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06200686 0,07608376 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06200686 0,07604557 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06200686 0,07600741 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,06200686 0,07596929 ! muscle cell development GO:0055001 52 32 0,000 0,06200686 0,07593121 ! mesoderm formation GO:0001707 73 32 0,000 0,06200686 0,07589317 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06200686 0,07585517 ! ovulation cycle GO:0042698 57 32 0,000 0,06200686 0,0758172 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06200686 0,07577927 ! hindbrain development GO:0030902 65 32 0,000 0,06200686 0,07574138 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06200686 0,07570353 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06200686 0,07566572 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,06200686 0,07562794 ! gene silencing GO:0016458 71 32 0,000 0,06200686 0,0755902 ! regulation of pH GO:0006885 56 33 0,000 0,06388222 0,07783753 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06388222 0,07779873 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,06388222 0,07775997 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06388222 0,07772124 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06388222 0,07768256 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06388222 0,07764391 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,06388222 0,0776053 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06388222 0,07756673 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06388222 0,07752819 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06388222 0,0774897 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06388222 0,07745124 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06388222 0,07741282 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06388222 0,07737444 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06575387 0,07960194 ! glial cell differentiation GO:0010001 67 34 0,000 0,06575387 0,07956251 ! post-embryonic development GO:0009791 76 34 0,000 0,06575387 0,07952312 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06575387 0,07948378 ! cholesterol transport GO:0030301 62 34 0,000 0,06575387 0,07944447 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06575387 0,0794052 ! spliceosome assembly GO:0000245 75 34 0,000 0,06575387 0,07936596 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06575387 0,07932677 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,06575387 0,07928762 ! formation of primary germ layer GO:0001704 76 34 0,000 0,06575387 0,0792485 ! cell fate specification GO:0001708 56 34 0,000 0,06575387 0,07920942 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,06575387 0,07917038 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06575387 0,07913138 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06575387 0,07909242 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,06575387 0,0790535 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06762184 0,0812593 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06762184 0,08121935 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06762184 0,08117944 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06762184 0,08113956 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06762184 0,08109973 ! membrane docking GO:0022406 69 35 0,000 0,06762184 0,08105994 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06762184 0,08102018 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06762184 0,08098047 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06762184 0,08094079 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06762184 0,08090115 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,06762184 0,08086155 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06762184 0,08082199 ! telencephalon development GO:0021537 81 35 0,000 0,06762184 0,08078247 ! sterol transport GO:0015918 63 35 0,000 0,06762184 0,08074299 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,06762184 0,08070354 ! placenta development GO:0001890 53 35 0,000 0,06762184 0,08066414 ! vesicle localization GO:0051648 70 35 0,000 0,06762184 0,08062477 ! regulation of muscle development GO:0048634 82 36 0,000 0,06948612 0,08280712 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,06948612 0,08276675 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,06948612 0,08272641 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,06948612 0,08268612 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,06948612 0,08264586 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,06948612 0,08260564 ! protein targeting to membrane GO:0006612 75 36 0,000 0,06948612 0,08256546 ! regulation of proteolysis GO:0030162 77 36 0,000 0,06948612 0,08252533 ! aerobic respiration GO:0009060 56 36 0,000 0,06948612 0,08248523 ! cytokine production GO:0001816 68 36 0,000 0,06948612 0,08244517 ! embryonic organ development GO:0048568 67 36 0,000 0,06948612 0,08240514 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,06948612 0,08236516 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,06948612 0,08232522 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07134673 0,08448864 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07134673 0,0844477 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07134673 0,08440681 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07134673 0,08436595 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07134673 0,08432514 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07134673 0,08428436 ! cell junction organization GO:0034330 96 37 0,000 0,07134673 0,08424363 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07134673 0,08420293 ! female gonad development GO:0008585 71 37 0,000 0,07134673 0,08416227 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07134673 0,08412165 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,07134673 0,08408107 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07134673 0,08404053 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,07320367 0,0861863 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07320367 0,08614478 ! meiosis I GO:0007127 74 38 0,000 0,07320367 0,08610331 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07320367 0,08606187 ! organic anion transport GO:0015711 82 38 0,000 0,07320367 0,08602048 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07320367 0,08597912 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,07320367 0,0859378 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07320367 0,08589653 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07320367 0,08585529 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07320367 0,08581409 ! spermatid development GO:0007286 69 38 0,000 0,07320367 0,08577293 ! pigment metabolic process GO:0042440 87 38 0,000 0,07320367 0,08573182 ! neural tube formation GO:0001841 79 38 0,000 0,07320367 0,08569074 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,07505695 0,08781807 ! negative regulation of binding GO:0051100 71 39 0,000 0,07505695 0,08777603 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,07505695 0,08773403 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,07505695 0,08769208 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,07505695 0,08765016 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,07505695 0,08760828 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,07505695 0,08756644 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,07505695 0,08752464 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,07505695 0,08748289 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07690658 0,08959598 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07690658 0,08955327 ! learning GO:0007612 82 40 0,000 0,07690658 0,08951061 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07690658 0,08946798 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07690658 0,0894254 ! lipid homeostasis GO:0055088 75 40 0,000 0,07690658 0,08938286 ! mismatch repair GO:0006298 58 40 0,000 0,07690658 0,08934035 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07690658 0,08929789 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,07690658 0,08925547 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07690658 0,08921309 ! RNA export from nucleus GO:0006405 61 41 0,000 0,07875255 0,0913111 ! mRNA catabolic process GO:0006402 79 41 0,000 0,07875255 0,09126779 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,07875255 0,09122451 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,07875255 0,09118128 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,07875255 0,09113808 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,07875255 0,09109493 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,07875255 0,09105182 ! feeding behavior GO:0007631 69 41 0,000 0,07875255 0,09100875 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,07875255 0,09096572 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,07875255 0,09092273 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,07875255 0,09087978 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,07875255 0,09083687 ! spermatid differentiation GO:0048515 73 41 0,000 0,07875255 0,090794 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,07875255 0,09075117 ! RNA modification GO:0009451 64 41 0,000 0,07875255 0,09070839 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,08059489 0,09278668 ! ear morphogenesis GO:0042471 64 42 0,000 0,08059489 0,09274297 ! organic ether metabolic process GO:0018904 59 42 0,000 0,08059489 0,09269931 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,08059489 0,09265568 ! T cell differentiation GO:0030217 93 42 0,000 0,08059489 0,0926121 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,08059489 0,09256856 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,08059489 0,09252506 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,08059489 0,0924816 ! regulation of protein secretion GO:0050708 77 42 0,000 0,08059489 0,09243818 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,08059489 0,0923948 ! cytokinesis GO:0000910 84 42 0,000 0,08059489 0,09235147 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,08059489 0,09230817 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,0824336 0,09436986 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,0824336 0,09432566 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,0824336 0,0942815 ! regulation of tube size GO:0035150 76 43 0,000 0,0824336 0,09423738 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,0824336 0,0941933 ! glucose transport GO:0015758 66 43 0,000 0,0824336 0,09414927 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,0824336 0,09410527 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,0824336 0,09406132 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,0824336 0,09401741 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,0824336 0,09397354 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,0824336 0,0939297 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,0824336 0,09388591 ! ion transmembrane transport GO:0034220 79 43 0,000 0,0824336 0,09384216 ! neuron migration GO:0001764 85 43 0,000 0,0824336 0,09379846 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,0824336 0,09375479 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,08426868 0,0957973 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,08426868 0,09575274 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,08426868 0,09570822 ! hexose transport GO:0008645 68 44 0,000 0,08426868 0,09566375 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,08426868 0,09561932 ! phagocytosis GO:0006909 105 44 0,000 0,08426868 0,09557493 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,08426868 0,09553057 ! double-strand break repair GO:0006302 85 44 0,000 0,08426868 0,09548627 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,08610014 0,0975163 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,08610014 0,09747111 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,08610014 0,09742596 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,08610014 0,09738086 ! biopolymer methylation GO:0043414 91 45 0,000 0,08610014 0,09733579 ! B cell differentiation GO:0030183 124 45 0,000 0,08610014 0,09729077 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,08610014 0,09724579 ! female gamete generation GO:0007292 71 45 0,000 0,08610014 0,09720086 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,08610014 0,09715596 ! polyol metabolic process GO:0019751 77 45 0,000 0,08610014 0,0971111 ! developmental growth GO:0048589 88 45 0,000 0,08610014 0,09706629 ! maintenance of location in cell GO:0051651 101 45 0,000 0,08610014 0,09702152 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,087928 0,09903554 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,087928 0,0989899 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,087928 0,09894431 ! glycolysis GO:0006096 71 46 0,000 0,087928 0,09889875 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,087928 0,09885324 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,087928 0,09880777 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,087928 0,09876234 ! neural tube development GO:0021915 91 47 0,000 0,08975224 0,10076504 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09157289 0,10276186 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09157289 0,10271468 ! mitochondrial transport GO:0006839 94 48 0,000 0,09157289 0,10266754 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,09157289 0,10262045 ! cellular component disassembly GO:0022411 89 48 0,000 0,09157289 0,10257339 ! endosome transport GO:0016197 127 48 0,000 0,09157289 0,10252639 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09157289 0,10247942 ! male sex differentiation GO:0046661 93 48 0,000 0,09157289 0,1024325 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09157289 0,10238562 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09157289 0,10233878 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09157289 0,10229199 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09157289 0,10224523 ! methylation GO:0032259 97 48 0,000 0,09157289 0,10219853 ! response to calcium ion GO:0051592 94 49 0,000 0,09338995 0,10417884 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,09338995 0,10413129 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,09338995 0,10408378 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,09338995 0,10403632 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,09338995 0,1039889 ! protein homooligomerization GO:0051260 84 49 0,000 0,09338995 0,10394153 ! regulation of action potential GO:0001508 102 50 0,000 0,09520343 0,10591164 ! regulation of ion transport GO:0043269 86 50 0,000 0,09520343 0,10586344 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,09520343 0,10581527 ! endocrine system development GO:0035270 109 50 0,000 0,09520343 0,10576715 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,09520343 0,10571908 ! activation of caspase activity GO:0006919 95 50 0,000 0,09520343 0,10567104 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09520343 0,10562306 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09520343 0,10557511 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09520343 0,10552721 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,09520343 0,10547935 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09520343 0,10543154 ! viral infectious cycle GO:0019058 104 51 0,000 0,09701333 0,1073872 ! peptide metabolic process GO:0006518 80 51 0,000 0,09701333 0,10733857 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09701333 0,10728997 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09701333 0,10724143 ! Notch signaling pathway GO:0007219 111 52 0,000 0,09881965 0,10918879 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,09881965 0,10913943 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,09881965 0,10909011 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,09881965 0,10904084 ! excretion GO:0007588 87 52 0,000 0,09881965 0,10899161 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,09881965 0,10894243 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,09881965 0,10889329 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,09881965 0,10884419 ! amino acid activation GO:0043038 98 52 0,000 0,09881965 0,10879514 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10062242 0,11072999 ! inner ear development GO:0048839 89 53 0,000 0,10062242 0,11068013 ! chromatin remodeling GO:0006338 122 53 0,000 0,10062242 0,11063032 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10062242 0,11058056 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10062242 0,11053083 ! vesicle organization GO:0016050 127 53 0,000 0,10062242 0,11048116 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,10062242 0,11043153 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 102 53 0,000 0,10062242 0,11038194 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,10242163 0,11230523 ! regulation of translational initiation GO:0006446 87 54 0,000 0,10242163 0,11225484 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,10242163 0,11220451 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,10242163 0,11215421 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,10242163 0,11210396 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,10242163 0,11205376 ! membrane fusion GO:0006944 122 54 0,000 0,10242163 0,1120036 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,10242163 0,11195349 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,10242163 0,11190342 ! regulation of cell shape GO:0008360 142 54 0,000 0,10242163 0,1118534 ! RNA catabolic process GO:0006401 103 55 0,000 0,1042173 0,11376356 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,1042173 0,11371275 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,1042173 0,11366199 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,1042173 0,11361127 ! cell recognition GO:0008037 98 55 0,000 0,1042173 0,11356059 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,1042173 0,11350997 ! cell maturation GO:0048469 107 55 0,000 0,1042173 0,11345938 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,1042173 0,11340884 ! response to UV GO:0009411 120 55 0,000 0,1042173 0,11335835 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,1042173 0,1133079 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,10600942 0,11520507 ! glucose catabolic process GO:0006007 88 56 0,000 0,10600942 0,11515385 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,10600942 0,11510267 ! regulation of DNA replication GO:0006275 105 56 0,000 0,10600942 0,11505153 ! RNA elongation GO:0006354 90 56 0,000 0,10600942 0,11500045 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,107798 0,11688882 ! chloride transport GO:0006821 102 57 0,000 0,107798 0,11683696 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,107798 0,11678515 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,107798 0,11673339 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,107798 0,11668167 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,107798 0,11662999 ! regulation of actin filament length GO:0030832 118 58 0,000 0,10958306 0,11850882 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,10958306 0,11845638 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,10958306 0,11840399 ! aging GO:0007568 112 58 0,000 0,10958306 0,11835164 ! gastrulation GO:0007369 122 58 0,000 0,10958306 0,11829934 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,10958306 0,11824709 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,10958306 0,11819488 ! maintenance of location GO:0051235 124 58 0,000 0,10958306 0,11814272 ! nuclear export GO:0051168 110 59 0,000 0,1113646 0,12001046 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1113646 0,11995754 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,11314262 0,12181905 ! DNA catabolic process GO:0006308 94 60 0,000 0,11314262 0,12176538 ! regulation of endocytosis GO:0030100 104 60 0,000 0,11314262 0,12171176 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,11314262 0,12165819 ! adult behavior GO:0030534 104 60 0,000 0,11314262 0,12160467 ! positive regulation of secretion GO:0051047 110 61 0,000 0,11491713 0,12345759 ! regulation of cellular component size GO:0032535 125 61 0,000 0,11491713 0,12340332 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,11491713 0,1233491 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,11491713 0,12329493 ! camera-type eye development GO:0043010 126 61 0,000 0,11491713 0,12324081 ! proton transport GO:0015992 117 61 0,000 0,11491713 0,12318673 ! viral reproductive process GO:0022415 132 62 0,000 0,11668815 0,12503033 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,11668815 0,12497551 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,11668815 0,12492075 ! tRNA processing GO:0008033 102 62 0,000 0,11668815 0,12486603 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,11668815 0,12481136 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,11845567 0,12664647 ! regulation of mitosis GO:0007088 112 63 0,000 0,11845567 0,12659107 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,11845567 0,12653572 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,11845567 0,12648042 ! hydrogen transport GO:0006818 121 64 0,000 0,1202197 0,12830787 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,1202197 0,12825185 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,1202197 0,12819586 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,12198025 0,13001647 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,12198025 0,12995977 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,12198025 0,12990312 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,12198025 0,12984652 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,12198025 0,12978996 ! ear development GO:0043583 114 66 0,000 0,12373733 0,13160222 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,12373733 0,13154495 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,12373733 0,13148773 ! gonad development GO:0008406 115 66 0,000 0,12373733 0,13143056 ! chromosome segregation GO:0007059 127 67 0,000 0,12549094 0,13323528 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,12549094 0,1331774 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,12549094 0,13311957 ! secondary metabolic process GO:0019748 125 67 0,000 0,12549094 0,13306179 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,12549094 0,13300407 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,12724109 0,13480052 ! hexose catabolic process GO:0019320 113 68 0,000 0,12724109 0,13474209 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,12724109 0,13468371 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,12724109 0,13462538 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,12724109 0,1345671 ! viral reproduction GO:0016032 142 68 0,000 0,12724109 0,13450887 ! regulation of lipase activity GO:0060191 137 68 0,000 0,12724109 0,13445069 ! adaptive immune response GO:0002250 126 68 0,000 0,12724109 0,13439256 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,12724109 0,13433448 ! cell projection assembly GO:0030031 138 68 0,000 0,12724109 0,13427646 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,12898779 0,13606096 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,12898779 0,13600224 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,12898779 0,13594356 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,12898779 0,13588494 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,12898779 0,13582637 ! developmental maturation GO:0021700 128 69 0,000 0,12898779 0,13576785 ! single fertilization GO:0007338 83 69 0,000 0,12898779 0,13570938 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,13073105 0,13748426 ! cell redox homeostasis GO:0045454 114 70 0,000 0,13073105 0,1374251 ! germ cell development GO:0007281 133 70 0,000 0,13073105 0,137366 ! activation of immune response GO:0002253 120 70 0,000 0,13073105 0,13730694 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,13073105 0,13724793 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,13247086 0,13901474 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,13247086 0,13895505 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,13247086 0,13889541 ! carbohydrate transport GO:0008643 114 72 0,000 0,13420724 0,14065563 ! actin filament organization GO:0007015 167 72 0,000 0,13420724 0,14059532 ! B cell activation GO:0042113 179 72 0,000 0,13420724 0,14053505 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,13420724 0,14047484 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,13420724 0,14041468 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,13420724 0,14035457 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,13420724 0,14029451 ! humoral immune response GO:0006959 115 73 0,000 0,13594019 0,14204529 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,13594019 0,14198456 ! regulation of immune effector process GO:0002697 156 73 0,000 0,13594019 0,14192388 ! acute inflammatory response GO:0002526 118 74 0,000 0,13766972 0,14366815 ! amino acid transport GO:0006865 148 74 0,000 0,13766972 0,1436068 ! regulation of caspase activity GO:0043281 136 74 0,000 0,13766972 0,14354551 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,13766972 0,14348427 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,13766972 0,14342308 ! organelle localization GO:0051640 155 74 0,000 0,13766972 0,14336195 ! transition metal ion transport GO:0000041 143 75 0,000 0,13939584 0,14509759 ! reproductive structure development GO:0048608 131 75 0,000 0,13939584 0,14503579 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,13939584 0,14497405 ! axon guidance GO:0007411 162 75 0,000 0,13939584 0,14491236 ! rhythmic process GO:0048511 142 75 0,000 0,13939584 0,14485072 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,14111855 0,1465785 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,14111855 0,1465162 ! learning or memory GO:0007611 161 76 0,000 0,14111855 0,14645396 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,14111855 0,14639177 ! regulation of blood pressure GO:0008217 134 76 0,000 0,14111855 0,14632964 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,14111855 0,14626755 ! amine catabolic process GO:0009310 136 77 0,000 0,14283787 0,14798681 ! neurotransmitter transport GO:0006836 142 77 0,000 0,14283787 0,14792408 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,14283787 0,1478614 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,14283787 0,14779877 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,14283787 0,1477362 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,14283787 0,14767368 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,14283787 0,14761121 ! regulation of catabolic process GO:0009894 173 77 0,000 0,14283787 0,1475488 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,14455379 0,1492582 ! antigen processing and presentation GO:0019882 117 78 0,000 0,14455379 0,14919514 ! fertilization GO:0009566 99 78 0,000 0,14455379 0,14913214 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,14455379 0,14906918 ! blood coagulation GO:0007596 151 79 0,000 0,14626632 0,15077157 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,14626632 0,15070798 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,14626632 0,15064444 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,14626632 0,15058096 ! protein oligomerization GO:0051259 149 79 0,000 0,14626632 0,15051753 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,14797547 0,15221224 ! meiosis GO:0007126 143 81 0,000 0,14968125 0,15390206 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,14968125 0,15383731 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,14968125 0,15377262 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,14968125 0,15370798 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,15138366 0,15539088 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,15138366 0,15532561 ! meiotic cell cycle GO:0051321 144 82 0,000 0,15138366 0,1552604 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,15308271 0,15693708 ! exocytosis GO:0006887 153 83 0,000 0,15308271 0,15687125 ! response to drug GO:0042493 149 83 0,000 0,15308271 0,15680548 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,15308271 0,15673976 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,15308271 0,1566741 ! inorganic anion transport GO:0015698 156 83 0,000 0,15308271 0,15660849 ! response to metal ion GO:0010038 158 84 0,000 0,15477841 0,15827696 ! T cell activation GO:0042110 189 84 0,000 0,15477841 0,15821073 ! response to nutrient GO:0007584 135 84 0,000 0,15477841 0,15814457 ! digestion GO:0007586 130 84 0,000 0,15477841 0,15807845 ! regulation of ligase activity GO:0051340 147 84 0,000 0,15477841 0,15801239 ! hemostasis GO:0007599 165 85 0,000 0,15647076 0,15967338 ! negative regulation of transport GO:0051051 164 85 0,000 0,15647076 0,15960671 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,15647076 0,15954009 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,15647076 0,15947354 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,15815977 0,16112774 ! regulation of lyase activity GO:0051339 169 86 0,000 0,15815977 0,16106057 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,15815977 0,16099346 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,15984544 0,16264157 ! mitochondrion organization GO:0007005 159 87 0,000 0,15984544 0,16257386 ! alcohol catabolic process GO:0046164 142 87 0,000 0,15984544 0,16250621 ! nucleosome assembly GO:0006334 126 87 0,000 0,15984544 0,16243861 ! cellular respiration GO:0045333 143 88 0,000 0,16152779 0,16408 ! sensory perception of smell GO:0007608 117 88 0,000 0,16152779 0,1640118 ! chromatin assembly GO:0031497 128 88 0,000 0,16152779 0,16394366 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,16152779 0,16387558 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,16320682 0,16551027 ! cellular defense response GO:0006968 123 89 0,000 0,16320682 0,1654416 ! response to inorganic substance GO:0010035 173 90 0,000 0,16488253 0,16707093 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,16488253 0,16700166 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,16488253 0,16693245 ! response to unfolded protein GO:0006986 139 90 0,000 0,16488253 0,1668633 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,16488253 0,16679421 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,16655493 0,16841626 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,16655493 0,16834658 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,16822403 0,16996332 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,16988983 0,17157539 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,16988983 0,17150449 ! vitamin metabolic process GO:0006766 153 93 0,000 0,16988983 0,17143365 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,17155235 0,1730398 ! female pregnancy GO:0007565 166 94 0,000 0,17155235 0,17296838 ! sterol metabolic process GO:0016125 166 94 0,000 0,17155235 0,17289702 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,17155235 0,17282573 ! regulation of membrane potential GO:0042391 179 94 0,000 0,17155235 0,17275449 ! regulation of defense response GO:0031347 171 95 0,000 0,17321158 0,17435348 ! nucleosome organization GO:0034728 143 95 0,000 0,17321158 0,17428167 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,17321158 0,17420992 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,17321158 0,17413823 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,17321158 0,17406659 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,17321158 0,17399502 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,17321158 0,17392351 ! sex differentiation GO:0007548 171 96 0,000 0,17486754 0,17551413 ! response to protein stimulus GO:0051789 158 96 0,000 0,17486754 0,17544205 ! regulation of T cell activation GO:0050863 175 96 0,000 0,17486754 0,17537003 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,17652022 0,17695482 ! transcription initiation GO:0006352 171 97 0,000 0,17652022 0,17688224 ! leukocyte differentiation GO:0002521 232 98 0,000 0,17816964 0,17846185 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,17816964 0,1783887 ! forebrain development GO:0030900 210 98 0,000 0,17816964 0,17831562 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,17816964 0,1782426 ! mRNA transport GO:0051028 185 100 0,000 0,18145872 0,18145872