pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/901-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 6,000 1,146E-08 2,637E-05 ! filopodium assembly GO:0046847 19 11 3,000 2,736E-07 3,146E-04 ! microspike assembly GO:0030035 23 12 3,000 4,086E-07 3,133E-04 ! nuclear migration GO:0007097 10 5 2,000 1,592E-06 9,154E-04 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 2,000 1,592E-06 7,323E-04 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 1,592E-06 6,103E-04 GO:0031272|regulation of pseudopodium assembly, ! macrophage differentiation GO:0030225 10 6 2,000 3,171E-06 1,042E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 3,668E-06 1,055E-03 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 5,528E-06 1,413E-03 ! establishment of nucleus localization GO:0040023 13 7 2,000 5,528E-06 1,271E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 2,000 8,809E-06 1,842E-03 ! nucleus localization GO:0051647 15 9 2,000 1,316E-05 2,523E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 1,502E-05 2,657E-03 ! negative regulation of kinase activity GO:0033673 100 58 4,000 1,636E-05 2,688E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 1,873E-05 2,871E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 1,873E-05 2,692E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 2,000 1,873E-05 2,534E-03 ! negative regulation of transferase activity GO:0051348 105 61 4,000 2,097E-05 2,68E-03 ! T cell proliferation GO:0042098 20 11 2,000 2,565E-05 3,105E-03 ! response to hypoxia GO:0001666 132 72 4,000 4,703E-05 5,408E-03 ! response to oxygen levels GO:0070482 137 74 4,000 5,368E-05 5,879E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 3,000 6,706E-05 7,011E-03 ! double-strand break repair GO:0006302 67 40 3,000 6,706E-05 6,706E-03 ! regulation of cell cycle process GO:0010564 122 81 4,000 8,283E-05 7,938E-03 ! regulation of DNA metabolic process GO:0051052 135 85 4,000 1,042E-04 9,589E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 1,102E-04 9,747E-03 ! response to UV GO:0009411 75 46 3,000 1,168E-04 9,946E-03 ! interphase GO:0051325 159 88 4,000 1,229E-04 0,01009338 ! negative regulation of neuron differentiation GO:0045665 24 18 2,000 1,233E-04 9,782E-03 ! estrogen receptor signaling pathway GO:0030520 30 18 2,000 1,233E-04 9,456E-03 ! leukocyte differentiation GO:0002521 143 90 4,000 1,367E-04 0,01013949 ! positive regulation of B cell activation GO:0050871 31 20 2,000 1,709E-04 0,01228679 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 1,986E-04 0,01384495 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 1,986E-04 0,01343775 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 1,986E-04 0,01305381 ! cell projection assembly GO:0030031 76 53 3,000 2,035E-04 0,01299891 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 2,291E-04 0,01424109 ! vasculogenesis GO:0001570 33 22 2,000 2,291E-04 0,01386632 ! neuron fate commitment GO:0048663 32 23 2,000 2,624E-04 0,01547565 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 2,624E-04 0,01508876 ! negative regulation of DNA replication GO:0008156 35 23 2,000 2,624E-04 0,01472074 ! lymphocyte proliferation GO:0046651 36 23 2,000 2,624E-04 0,01437025 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 2,624E-04 0,01403606 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 2,887E-04 0,01509003 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,952E-04 0,01508952 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 2,952E-04 0,01476149 ! induction of apoptosis by oxidative stress GO:0008631 5 5 1,000 2,952E-04 0,01444741 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 2,952E-04 0,01414642 GO:0045686|negative regulation of glial cell differentiation, ! negative regulation of T cell mediated immunity GO:0002710 11 5 1,000 2,952E-04 0,01385772 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 1,000 2,952E-04 0,01358057 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 1,000 2,952E-04 0,01331428 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 2,952E-04 0,01305824 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 1,000 2,952E-04 0,01281186 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! positive regulation of cell projection organization GO:0031346 39 24 2,000 2,987E-04 0,01272281 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 2,987E-04 0,01249149 ! mitochondrial membrane organization GO:0007006 39 24 2,000 2,987E-04 0,01226843 ! negative regulation of cell development GO:0010721 56 24 2,000 2,987E-04 0,01205319 GO:0050768|negative regulation of neurogenesis, ! lung development GO:0030324 94 59 3,000 3,084E-04 0,01222882 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 3,381E-04 0,01317995 GO:0045936|negative regulation of phosphate metabolic process, ! leukocyte proliferation GO:0070661 39 25 2,000 3,381E-04 0,01296029 GO:0032943|mononuclear cell proliferation, ! respiratory tube development GO:0030323 99 62 3,000 3,733E-04 0,01407369 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 3,969E-04 0,01472368 ! cell cycle checkpoint GO:0000075 108 64 3,000 4,216E-04 0,0153914 ! respiratory system development GO:0060541 100 64 3,000 4,216E-04 0,01515091 ! regulation of helicase activity GO:0051095 11 6 1,000 4,413E-04 0,01561378 ! male meiosis GO:0007140 7 6 1,000 4,413E-04 0,0153772 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 4,413E-04 0,01514769 ! mRNA stabilization GO:0048255 15 6 1,000 4,413E-04 0,01492493 GO:0043489|RNA stabilization, ! thymic T cell selection GO:0045061 12 6 1,000 4,413E-04 0,01470863 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 4,413E-04 0,01449851 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 1,000 4,413E-04 0,0142943 ! ER overload response GO:0006983 7 6 1,000 4,413E-04 0,01409577 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 4,413E-04 0,01390268 ! protein import into mitochondrial inner membrane GO:0045039 6 6 1,000 4,413E-04 0,0137148 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 4,413E-04 0,01353194 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 4,413E-04 0,01335389 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 4,759E-04 0,01421375 ! regulation of B cell activation GO:0050864 42 28 2,000 4,759E-04 0,01403152 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 6,156E-04 0,01792112 ! T-helper 1 type immune response GO:0042088 11 7 1,000 6,156E-04 0,0176971 ! positive regulation of isotype switching GO:0045830 15 7 1,000 6,156E-04 0,01747862 GO:0045911|positive regulation of DNA recombination, ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 6,156E-04 0,01726546 ! fibrinolysis GO:0042730 9 7 1,000 6,156E-04 0,01705745 ! B cell lineage commitment GO:0002326 17 7 1,000 6,156E-04 0,01685438 ! spinal cord motor neuron differentiation GO:0021522 9 7 1,000 6,156E-04 0,0166561 ! T cell lineage commitment GO:0002360 12 7 1,000 6,156E-04 0,01646242 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 1,000 6,156E-04 0,0162732 GO:0002714|positive regulation of B cell mediated immunity, ! response to tumor cell GO:0002347 12 7 1,000 6,156E-04 0,01608827 ! neuroblast proliferation GO:0007405 13 7 1,000 6,156E-04 0,01590751 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 1,000 6,156E-04 0,01573076 ! B cell receptor signaling pathway GO:0050853 11 7 1,000 6,156E-04 0,01555789 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 1,000 6,156E-04 0,01538878 ! mitochondrion organization GO:0007005 104 73 3,000 6,955E-04 0,01720101 ! negative regulation of DNA metabolic process GO:0051053 48 32 2,000 7,091E-04 0,01735021 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 7,769E-04 0,01880947 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 8,178E-04 0,0195931 ! induction of positive chemotaxis GO:0050930 14 8 1,000 8,178E-04 0,0193911 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 8,178E-04 0,01919324 ! inner mitochondrial membrane organization GO:0007007 11 8 1,000 8,178E-04 0,01899936 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 8,178E-04 0,01880937 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,178E-04 0,01862314 ! regulation of Notch signaling pathway GO:0008593 18 8 1,000 8,178E-04 0,01844056 ! regulation of gliogenesis GO:0014013 20 8 1,000 8,178E-04 0,01826153 GO:0045685|regulation of glial cell differentiation, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 8,178E-04 0,01808593 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 8,178E-04 0,01791369 GO:0000076|DNA replication checkpoint, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 8,178E-04 0,01774469 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 8,487E-04 0,01824353 ! DNA integrity checkpoint GO:0031570 57 34 2,000 8,487E-04 0,01807461 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 8,487E-04 0,01790878 ! positive regulation of leukocyte proliferation GO:0070665 50 35 2,000 9,246E-04 0,01933275 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! T cell activation GO:0042110 134 79 3,000 9,363E-04 0,01940167 ! lung alveolus development GO:0048286 17 9 1,000 1,048E-03 0,02151517 ! ventral spinal cord development GO:0021517 11 9 1,000 1,048E-03 0,02132477 ! T cell selection GO:0045058 18 9 1,000 1,048E-03 0,02113771 ! regulation of DNA replication initiation GO:0030174 13 9 1,000 1,048E-03 0,0209539 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 1,000 1,048E-03 0,02077327 GO:0002820|negative regulation of adaptive immune response, ! localization within membrane GO:0051668 15 9 1,000 1,048E-03 0,02059572 ! neuron fate specification GO:0048665 11 10 1,000 1,305E-03 0,02543522 ! hippocampus development GO:0021766 19 10 1,000 1,305E-03 0,02522148 ! blood vessel remodeling GO:0001974 21 10 1,000 1,305E-03 0,0250113 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,305E-03 0,0248046 ! response to X-ray GO:0010165 16 10 1,000 1,305E-03 0,02460128 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,305E-03 0,02440127 ! regulation of bone resorption GO:0045124 24 10 1,000 1,305E-03 0,02420448 ! alpha-beta T cell activation GO:0046631 16 10 1,000 1,305E-03 0,02401085 ! regulation of B cell differentiation GO:0045577 16 10 1,000 1,305E-03 0,02382029 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,305E-03 0,02363272 ! T cell receptor signaling pathway GO:0050852 18 10 1,000 1,305E-03 0,02344809 ! negative regulation of immune effector process GO:0002698 16 10 1,000 1,305E-03 0,02326633 ! T cell differentiation GO:0030217 65 40 2,000 1,368E-03 0,02420887 ! regulation of neurogenesis GO:0050767 153 89 3,000 1,459E-03 0,02562286 ! mitochondrial transport GO:0006839 60 42 2,000 1,577E-03 0,02748435 ! ER-associated protein catabolic process GO:0030433 14 11 1,000 1,589E-03 0,02748283 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,589E-03 0,02727773 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,589E-03 0,02707567 GO:0000725|recombinational repair, ! regulation of positive chemotaxis GO:0050926 17 11 1,000 1,589E-03 0,02687659 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,589E-03 0,02668041 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,589E-03 0,02648707 ! positive regulation of T cell mediated immunity GO:0002711 18 11 1,000 1,589E-03 0,02629652 ! regulation of isotype switching GO:0045191 19 11 1,000 1,589E-03 0,02610869 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,589E-03 0,02592352 ! cell fate commitment GO:0045165 141 92 3,000 1,649E-03 0,02671462 ! activation of caspase activity GO:0006919 65 43 2,000 1,689E-03 0,02716506 ! DNA-dependent DNA replication GO:0006261 59 43 2,000 1,689E-03 0,02697642 ! response to insulin stimulus GO:0032868 63 43 2,000 1,689E-03 0,02679037 ! regulation of cell projection organization GO:0031344 83 44 2,000 1,805E-03 0,02844081 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 1,805E-03 0,02824734 ! auditory receptor cell differentiation GO:0042491 25 12 1,000 1,9E-03 0,02953103 ! histone acetylation GO:0016573 23 12 1,000 1,9E-03 0,02933283 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,9E-03 0,02913728 ! response to gamma radiation GO:0010332 20 12 1,000 1,9E-03 0,02894432 ! regulation of mRNA stability GO:0043488 27 12 1,000 1,9E-03 0,02875389 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 1,9E-03 0,02856596 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 1,927E-03 0,02877512 ! response to light stimulus GO:0009416 153 96 3,000 1,928E-03 0,02861602 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 2,184E-03 0,03220389 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,238E-03 0,03278219 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 1,000 2,238E-03 0,0325747 ! cell differentiation in spinal cord GO:0021515 16 13 1,000 2,238E-03 0,03236983 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 2,238E-03 0,03216752 ! regulation of cellular pH GO:0030641 20 13 1,000 2,238E-03 0,03196772 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 2,238E-03 0,03177039 ! regulation of RNA stability GO:0043487 28 13 1,000 2,238E-03 0,03157548 ! positive regulation of caspase activity GO:0043280 72 48 2,000 2,321E-03 0,03254609 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 2,000 2,321E-03 0,03234884 ! regulation of S phase GO:0033261 18 14 1,000 2,601E-03 0,03604321 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,601E-03 0,03582739 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2,601E-03 0,03561413 ! limbic system development GO:0021761 25 14 1,000 2,601E-03 0,03540339 ! pituitary gland development GO:0021983 23 14 1,000 2,601E-03 0,03519514 ! cellular response to starvation GO:0009267 21 14 1,000 2,601E-03 0,03498932 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,601E-03 0,03478589 ! G1/S transition checkpoint GO:0031575 33 14 1,000 2,601E-03 0,03458482 ! DNA unwinding during replication GO:0006268 21 14 1,000 2,601E-03 0,03438606 ! T cell differentiation in the thymus GO:0033077 27 14 1,000 2,601E-03 0,03418956 ! negative regulation of blood coagulation GO:0030195 19 14 1,000 2,601E-03 0,0339953 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,601E-03 0,03380324 ! positive regulation of cell migration GO:0030335 92 51 2,000 2,761E-03 0,03567855 ! establishment of organelle localization GO:0051656 85 52 2,000 2,919E-03 0,03750282 ! lipid phosphorylation GO:0046834 23 15 1,000 2,991E-03 0,03821685 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 2,991E-03 0,03800571 ! DNA integration GO:0015074 22 15 1,000 2,991E-03 0,03779689 ! regulation of T cell mediated immunity GO:0002709 26 15 1,000 2,991E-03 0,03759035 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,991E-03 0,03738605 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,991E-03 0,03718396 ! defense response to virus GO:0051607 27 15 1,000 2,991E-03 0,03698405 ! regulation of protein complex assembly GO:0043254 81 54 2,000 3,25E-03 0,0399734 ! regulation of mitosis GO:0007088 84 54 2,000 3,25E-03 0,03976078 GO:0051783|regulation of nuclear division, ! protein amino acid acetylation GO:0006473 28 16 1,000 3,406E-03 0,04144824 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,406E-03 0,04123009 GO:0030968|endoplasmic reticulum unfolded protein response, ! negative regulation of immune response GO:0050777 28 16 1,000 3,406E-03 0,04101423 ! DNA replication initiation GO:0006270 25 16 1,000 3,406E-03 0,04080061 ! diencephalon development GO:0021536 25 16 1,000 3,406E-03 0,04058921 ! protein localization in mitochondrion GO:0070585 22 16 1,000 3,406E-03 0,04037999 GO:0006626|protein targeting to mitochondrion, ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 1,000 3,406E-03 0,04017291 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 3,406E-03 0,03996795 ! inner ear receptor cell differentiation GO:0060113 30 16 1,000 3,406E-03 0,03976506 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 3,603E-03 0,04185882 ! positive regulation of cell motion GO:0051272 99 56 2,000 3,603E-03 0,04164848 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 3,789E-03 0,04357004 ! positive regulation of cell killing GO:0031343 24 17 1,000 3,846E-03 0,04401277 ! DNA duplex unwinding GO:0032508 25 17 1,000 3,846E-03 0,04379489 GO:0032392|DNA geometric change, ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 3,846E-03 0,04357915 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 1,000 3,846E-03 0,04336552 GO:0002712|regulation of B cell mediated immunity, ! negative regulation of intracellular transport GO:0032387 29 17 1,000 3,846E-03 0,04315399 ! regulation of immunoglobulin production GO:0002637 25 17 1,000 3,846E-03 0,0429445 ! proximal/distal pattern formation GO:0009954 25 17 1,000 3,846E-03 0,04273704 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 3,846E-03 0,04253157 ! negative regulation of coagulation GO:0050819 23 17 1,000 3,846E-03 0,04232807 ! myeloid cell differentiation GO:0030099 85 59 2,000 4,176E-03 0,04574023 ! mechanoreceptor differentiation GO:0042490 32 18 1,000 4,312E-03 0,04699966 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 4,312E-03 0,04677796 ! somitogenesis GO:0001756 24 18 1,000 4,312E-03 0,04655834 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 1,000 4,312E-03 0,04634078 ! cellular response to nutrient levels GO:0031669 27 18 1,000 4,312E-03 0,04612524 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 4,312E-03 0,0459117 ! regulation of homeostatic process GO:0032844 105 60 2,000 4,379E-03 0,04641092 ! meiosis GO:0007126 96 61 2,000 4,587E-03 0,04839623 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell growth GO:0030308 106 62 2,000 4,801E-03 0,0504255 ! meiotic cell cycle GO:0051321 97 62 2,000 4,801E-03 0,0501963 ! organelle localization GO:0051640 96 62 2,000 4,801E-03 0,04996916 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 4,802E-03 0,04974842 ! reciprocal meiotic recombination GO:0007131 31 19 1,000 4,802E-03 0,04952534 ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 4,802E-03 0,04930424 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 4,802E-03 0,04908511 ! response to starvation GO:0042594 30 19 1,000 4,802E-03 0,04886792 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 4,802E-03 0,04865264 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 5,022E-03 0,05065658 ! negative regulation of cell size GO:0045792 108 64 2,000 5,248E-03 0,05270756 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 5,316E-03 0,05316344 ! pallium development GO:0021543 38 20 1,000 5,316E-03 0,0529333 ! positive regulation of locomotion GO:0040017 35 20 1,000 5,316E-03 0,05270514 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! spinal cord development GO:0021510 31 20 1,000 5,316E-03 0,05247893 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 5,316E-03 0,05225466 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 1,000 5,316E-03 0,0520323 ! regulation of caspase activity GO:0043281 97 65 2,000 5,48E-03 0,05340796 ! protein oligomerization GO:0051259 100 65 2,000 5,48E-03 0,05318261 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 5,718E-03 0,05526278 ! regulation of cell killing GO:0031341 34 21 1,000 5,855E-03 0,05634566 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 5,855E-03 0,05611089 ! protein amino acid acylation GO:0043543 37 21 1,000 5,855E-03 0,05587806 ! regulation of chemotaxis GO:0050920 36 21 1,000 5,855E-03 0,05564716 ! regulation of DNA recombination GO:0000018 40 21 1,000 5,855E-03 0,05541816 ! ovarian follicle development GO:0001541 30 21 1,000 5,855E-03 0,05519104 ! cell aging GO:0007569 32 21 1,000 5,855E-03 0,05496577 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 5,855E-03 0,05474233 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 5,855E-03 0,0545207 ! immunoglobulin production GO:0002377 33 21 1,000 5,855E-03 0,05430086 GO:0002440|production of molecular mediator of immune response, ! positive regulation of adaptive immune response GO:0002821 31 21 1,000 5,855E-03 0,05408278 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 5,963E-03 0,05485968 ! regulation of neuron differentiation GO:0045664 107 67 2,000 5,963E-03 0,05464111 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 6,418E-03 0,05857374 ! leukocyte adhesion GO:0007159 38 22 1,000 6,418E-03 0,05834222 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 6,418E-03 0,05811253 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 6,418E-03 0,05788464 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of behavior GO:0050795 38 22 1,000 6,418E-03 0,05765853 ! regulation of blood coagulation GO:0030193 34 22 1,000 6,418E-03 0,05743417 ! protein tetramerization GO:0051262 39 22 1,000 6,418E-03 0,05721156 ! lymphocyte differentiation GO:0030098 113 71 2,000 7,003E-03 0,06219079 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 7,004E-03 0,0619572 ! cell fate determination GO:0001709 45 23 1,000 7,004E-03 0,06171981 ! spermatid development GO:0007286 33 23 1,000 7,004E-03 0,06148424 ! liver development GO:0001889 40 23 1,000 7,004E-03 0,06125046 ! regulation of peptidase activity GO:0052547 106 72 2,000 7,279E-03 0,06341561 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 7,613E-03 0,06607871 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 7,613E-03 0,06583029 ! base-excision repair GO:0006284 31 24 1,000 7,613E-03 0,06558373 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 1,000 7,613E-03 0,06533902 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 7,613E-03 0,06509612 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 7,85E-03 0,06686787 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 7,85E-03 0,06662113 ! blood coagulation GO:0007596 116 75 2,000 8,145E-03 0,0688705 GO:0050817|coagulation, ! negative regulation of growth GO:0045926 123 75 2,000 8,145E-03 0,06861823 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 8,246E-03 0,06921869 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 8,902E-03 0,07444892 ! regulation of pH GO:0006885 36 26 1,000 8,902E-03 0,07417917 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 8,902E-03 0,07391138 ! negative regulation of protein modification process GO:0031400 50 26 1,000 8,902E-03 0,07364551 ! spermatid differentiation GO:0048515 36 26 1,000 8,902E-03 0,07338155 ! regulation of coagulation GO:0050818 39 26 1,000 8,902E-03 0,07311947 ! response to ionizing radiation GO:0010212 47 27 1,000 9,579E-03 0,07840869 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 1,000 9,579E-03 0,07813064 ! natural killer cell activation GO:0030101 35 27 1,000 9,579E-03 0,07785456 ! negative regulation of protein transport GO:0051224 49 27 1,000 9,579E-03 0,07758043 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 9,717E-03 0,07841877 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 2,000 9,717E-03 0,07814458 ! hemostasis GO:0007599 125 81 2,000 0,0100513 0,08055046 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,0100513 0,08027077 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,01027978 0,08181137 ! immune response-activating signal transduction GO:0002757 38 28 1,000 0,01027978 0,08152926 GO:0002764|immune response-regulating signal transduction, ! ossification GO:0001503 134 82 2,000 0,01039212 0,08213699 GO:0060348|bone development, ! ovulation cycle process GO:0022602 41 29 1,000 0,01100208 0,08666023 ! positive regulation of T cell proliferation GO:0042102 44 29 1,000 0,01100208 0,08636447 ! protein targeting to membrane GO:0006612 53 29 1,000 0,01100208 0,08607071 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01100208 0,08577894 ! telencephalon development GO:0021537 52 29 1,000 0,01100208 0,08548915 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,01145458 0,0887055 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,01145458 0,08840783 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 0,01145458 0,08811216 ! ovulation cycle GO:0042698 43 30 1,000 0,01174615 0,09005385 ! positive regulation of immune effector process GO:0002699 40 30 1,000 0,01174615 0,08975467 ! cell cycle arrest GO:0007050 150 86 2,000 0,01182215 0,09003621 ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,01219645 0,09258032 ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01251174 0,09466119 ! segmentation GO:0035282 41 31 1,000 0,01251174 0,09435082 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01251174 0,09404249 ! cell fate specification GO:0001708 37 31 1,000 0,01251174 0,09373616 ! meiosis I GO:0007127 52 32 1,000 0,01329858 0,0993076 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 0,01329858 0,09898621 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01329858 0,0986669 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01329858 0,09834965 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,01329858 0,09803442 ! female gonad development GO:0008585 49 33 1,000 0,01410643 0,10365749 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01410643 0,10332737 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,01410643 0,10299935 ! cytokinesis GO:0000910 52 33 1,000 0,01410643 0,1026734 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01493504 0,10836148 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,01493504 0,10802072 ! Notch signaling pathway GO:0007219 56 35 1,000 0,01578416 0,11380426 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,01578416 0,11344862 ! protein homooligomerization GO:0051260 52 35 1,000 0,01578416 0,1130952 ! regulation of response to external stimulus GO:0032101 139 96 2,000 0,01587135 0,11336676 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,01587135 0,11301578 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01665354 0,11821956 GO:0090047|positive regulation of transcription regulator activity, ! tissue remodeling GO:0048771 62 36 1,000 0,01665354 0,11785581 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,01665354 0,11749428 GO:0046660|female sex differentiation, ! protein import GO:0017038 156 99 2,000 0,01721987 0,12111837 ! regulation of body fluid levels GO:0050878 154 100 2,000 0,01768321 0,1239981 ! protein localization in organelle GO:0033365 161 100 2,000 0,01768321 0,1236212 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,01845212 0,12860571 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 1,000 0,01938085 0,13467054 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01938085 0,13426491 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 0,01938085 0,13386171 ! JNK cascade GO:0007254 54 39 1,000 0,01938085 0,13346093 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 0,02032887 0,13957138 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,02032887 0,13915599 ! inner ear development GO:0048839 57 40 1,000 0,02032887 0,13874306 ! B cell differentiation GO:0030183 62 40 1,000 0,02032887 0,13833258 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,02129597 0,14448594 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 0,02129597 0,14406098 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,02129597 0,14363851 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,0222819 0,14984904 ! regulation of cell shape GO:0008360 78 42 1,000 0,0222819 0,14941216 ! positive regulation of binding GO:0051099 59 43 1,000 0,02328643 0,15569419 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,02328643 0,1552429 ! neuromuscular process GO:0050905 79 43 1,000 0,02328643 0,15479422 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,02328643 0,15434813 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,0253504 0,16754572 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,0253504 0,16706565 ! cell maturation GO:0048469 60 45 1,000 0,0253504 0,16658832 ! histone modification GO:0016570 68 46 1,000 0,02640937 0,17305286 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,02640937 0,17256123 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02715999 0,17696309 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02715999 0,17646319 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02715999 0,17596611 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02715999 0,17547182 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02715999 0,17498031 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02715999 0,17449153 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02715999 0,17400549 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02715999 0,17352214 ! sleep GO:0030431 11 5 0,000 0,02715999 0,17304147 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02715999 0,17256345 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02715999 0,17208807 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02715999 0,1716153 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02715999 0,17114512 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02715999 0,17067751 ! tongue development GO:0043586 6 5 0,000 0,02715999 0,17021245 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02715999 0,16974992 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02715999 0,16928989 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02715999 0,16883235 ! cobalt ion transport GO:0006824 9 5 0,000 0,02715999 0,16837728 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02715999 0,16792465 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02715999 0,16747445 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02715999 0,16702666 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02715999 0,16658125 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02715999 0,16613822 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02715999 0,16569753 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02715999 0,16525918 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02715999 0,16482314 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02715999 0,16438939 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02715999 0,16395793 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02715999 0,16352872 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02715999 0,16310175 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02715999 0,162677 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02715999 0,16225447 ! malate metabolic process GO:0006108 7 5 0,000 0,02715999 0,16183412 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02715999 0,16141594 ! behavioral response to pain GO:0048266 7 5 0,000 0,02715999 0,16099992 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02715999 0,16058604 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02715999 0,16017428 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02715999 0,15976463 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02715999 0,15935706 ! mating behavior GO:0007617 6 5 0,000 0,02715999 0,15895158 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02715999 0,15854815 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02715999 0,15814676 ! rhythmic behavior GO:0007622 12 5 0,000 0,02715999 0,1577474 ! copulation GO:0007620 7 5 0,000 0,02715999 0,15735005 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02715999 0,1569547 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02715999 0,15656133 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02715999 0,15616992 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02715999 0,15578047 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02715999 0,15539296 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02715999 0,15500737 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02715999 0,15462369 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02715999 0,1542419 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02715999 0,15386199 ! response to protozoan GO:0001562 9 5 0,000 0,02715999 0,15348395 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02715999 0,15310777 ! lymph vessel development GO:0001945 7 5 0,000 0,02715999 0,15273342 ! endochondral ossification GO:0001958 12 5 0,000 0,02715999 0,1523609 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02715999 0,15199019 ! parathyroid gland development GO:0060017 8 5 0,000 0,02715999 0,15162129 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02715999 0,15125416 ! anagen GO:0042640 6 5 0,000 0,02715999 0,15088882 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02715999 0,15052523 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02715999 0,15016339 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02715999 0,14980328 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02715999 0,1494449 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02715999 0,14908823 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02715999 0,14873326 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02715999 0,14837997 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02715999 0,14802836 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02715999 0,14767841 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02715999 0,14733012 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02715999 0,14698346 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02715999 0,14663843 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02715999 0,14629501 ! ovulation GO:0030728 6 5 0,000 0,02715999 0,1459532 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02715999 0,14561298 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02715999 0,14527435 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02715999 0,14493728 ! response to pH GO:0009268 9 5 0,000 0,02715999 0,14460178 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02715999 0,14426783 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02715999 0,14393541 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02715999 0,14360453 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02715999 0,14327516 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02715999 0,1429473 ! polyol catabolic process GO:0046174 7 5 0,000 0,02715999 0,14262093 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02715999 0,14229606 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02715999 0,14197266 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02715999 0,14165072 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02715999 0,14133025 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02715999 0,14101122 ! urea metabolic process GO:0019627 6 5 0,000 0,02715999 0,14069362 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02715999 0,14037746 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02715999 0,14006271 ! neutrophil activation GO:0042119 5 5 0,000 0,02715999 0,13974937 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02715999 0,13943743 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02715999 0,13912688 ! response to food GO:0032094 5 5 0,000 0,02715999 0,13881771 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02715999 0,13850991 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02715999 0,13820347 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02715999 0,13789839 ! forebrain neuron development GO:0021884 7 5 0,000 0,02715999 0,13759465 ! melanosome organization GO:0032438 7 5 0,000 0,02715999 0,13729224 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02715999 0,13699116 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02715999 0,1366914 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02715999 0,13639295 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02715999 0,13609579 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02715999 0,13579993 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02715999 0,13550536 ! nucleoside transport GO:0015858 6 5 0,000 0,02715999 0,13521206 ! nucleoside salvage GO:0043174 7 5 0,000 0,02715999 0,13492002 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02715999 0,13462924 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02715999 0,13433972 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02715999 0,13405144 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02715999 0,13376439 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02715999 0,13347857 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02715999 0,13319396 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02715999 0,13291057 ! depyrimidination GO:0045008 8 5 0,000 0,02715999 0,13262839 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02715999 0,13234739 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02715999 0,13206759 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02715999 0,13178897 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02715999 0,13151151 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02715999 0,13123523 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02715999 0,1309601 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02715999 0,13068613 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02715999 0,1304133 ! monocyte differentiation GO:0030224 8 5 0,000 0,02715999 0,1301416 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02715999 0,12987104 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02715999 0,1296016 ! centrosome duplication GO:0051298 5 5 0,000 0,02715999 0,12933327 ! response to UV-C GO:0010225 6 5 0,000 0,02715999 0,12906605 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02715999 0,12879994 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02715999 0,12853492 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02715999 0,12827098 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02715999 0,12800813 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02715999 0,12774636 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02715999 0,12748565 ! melanosome transport GO:0032402 8 5 0,000 0,02715999 0,12722601 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02715999 0,12696742 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02715999 0,12670988 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02715999 0,12645338 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02715999 0,12619792 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02715999 0,12594349 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02715999 0,12569008 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02715999 0,12543769 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02715999 0,12518631 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02715999 0,12493594 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02715999 0,12468657 ! neural tube patterning GO:0021532 6 5 0,000 0,02715999 0,12443819 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02715999 0,12419079 ! histone demethylation GO:0016577 9 5 0,000 0,02715999 0,12394438 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02715999 0,12369895 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02715999 0,12345449 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02715999 0,12321099 ! enteric nervous system development GO:0048484 8 5 0,000 0,02715999 0,12296844 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02715999 0,12272686 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02715999 0,12248621 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02715999 0,12224652 ! transcription termination GO:0006353 8 5 0,000 0,02715999 0,12200775 ! plasminogen activation GO:0031639 5 5 0,000 0,02715999 0,12176992 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02715999 0,12153301 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02715999 0,12129703 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02715999 0,12106196 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02715999 0,12082779 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02715999 0,12059454 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02715999 0,12036218 ! apical protein localization GO:0045176 6 5 0,000 0,02715999 0,12013071 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02715999 0,11990013 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02715999 0,11967044 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02715999 0,11944162 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02715999 0,11921368 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02715999 0,11898661 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02715999 0,1187604 ! glial cell migration GO:0008347 10 5 0,000 0,02715999 0,11853505 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02715999 0,11831055 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02715999 0,1180869 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02715999 0,11786409 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02715999 0,11764213 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02715999 0,117421 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02715999 0,11720069 ! neural plate development GO:0001840 6 5 0,000 0,02715999 0,11698122 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02715999 0,11676256 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02715999 0,11654472 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02715999 0,11632769 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02715999 0,11611147 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02715999 0,11589605 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02715999 0,11568142 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02715999 0,1154676 ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02715999 0,11525456 ! spindle assembly GO:0051225 5 5 0,000 0,02715999 0,1150423 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02715999 0,11483083 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02715999 0,11462013 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02715999 0,1144102 ! organ regeneration GO:0031100 7 5 0,000 0,02715999 0,11420104 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02715999 0,11399265 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02715999 0,11378501 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02715999 0,11357813 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02715999 0,113372 GO:0055081|anion homeostasis, ! endocrine system development GO:0035270 83 47 1,000 0,02748604 0,11452518 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02748604 0,11431808 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,02748604 0,11411173 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,02748604 0,11390612 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,02858019 0,1182274 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,02969159 0,12260441 ! germ cell development GO:0007281 68 49 1,000 0,02969159 0,12238469 ! ear development GO:0043583 72 50 1,000 0,03082003 0,1268087 ! lipid modification GO:0030258 73 50 1,000 0,03082003 0,12658226 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,03196529 0,13105197 GO:0010863|positive regulation of phospholipase C activity, ! tRNA transcription GO:0009304 11 6 0,000 0,03250373 0,13302239 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03250373 0,13278612 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03250373 0,13255068 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03250373 0,13231608 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03250373 0,1320823 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03250373 0,13184935 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03250373 0,13161723 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03250373 0,13138591 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03250373 0,13115541 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03250373 0,13092572 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03250373 0,13069683 ! prostate gland development GO:0030850 9 6 0,000 0,03250373 0,13046873 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03250373 0,13024144 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03250373 0,13001493 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03250373 0,12978921 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03250373 0,12956427 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03250373 0,12934011 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03250373 0,12911673 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03250373 0,12889411 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03250373 0,12867226 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,03250373 0,12845118 ! neuron adhesion GO:0007158 9 6 0,000 0,03250373 0,12823085 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03250373 0,12801127 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03250373 0,12779245 ! signal peptide processing GO:0006465 8 6 0,000 0,03250373 0,12757438 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03250373 0,12735704 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03250373 0,12714045 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03250373 0,12692459 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03250373 0,12670946 ! opsonization GO:0008228 8 6 0,000 0,03250373 0,12649507 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03250373 0,12628139 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03250373 0,12606844 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03250373 0,1258562 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03250373 0,12564468 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03250373 0,12543387 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03250373 0,12522376 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03250373 0,12501435 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03250373 0,12480565 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03250373 0,12459764 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03250373 0,12439032 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03250373 0,12418369 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03250373 0,12397775 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03250373 0,12377249 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03250373 0,12356791 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03250373 0,123364 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03250373 0,12316076 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03250373 0,1229582 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03250373 0,1227563 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03250373 0,12255506 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03250373 0,12235448 ! protein lipoylation GO:0009249 10 6 0,000 0,03250373 0,12215455 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03250373 0,12195528 ! pigment granule organization GO:0048753 11 6 0,000 0,03250373 0,12175665 ! drug transport GO:0015893 6 6 0,000 0,03250373 0,12155867 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03250373 0,12136134 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03250373 0,12116464 ! histidine metabolic process GO:0006547 6 6 0,000 0,03250373 0,12096858 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03250373 0,12077316 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03250373 0,12057836 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03250373 0,12038419 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03250373 0,12019065 ! adenohypophysis development GO:0021984 10 6 0,000 0,03250373 0,11999773 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03250373 0,11980542 ! hyperosmotic response GO:0006972 8 6 0,000 0,03250373 0,11961373 ! microtubule nucleation GO:0007020 10 6 0,000 0,03250373 0,11942266 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03250373 0,11923219 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03250373 0,11904233 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03250373 0,11885308 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03250373 0,11866442 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03250373 0,11847636 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03250373 0,1182889 ! response to dietary excess GO:0002021 7 6 0,000 0,03250373 0,11810203 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03250373 0,11791575 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03250373 0,11773005 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03250373 0,11754494 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03250373 0,11736041 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03250373 0,11717646 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03250373 0,11699309 ! neuron apoptosis GO:0051402 8 6 0,000 0,03250373 0,11681029 ! organic alcohol transport GO:0015850 9 6 0,000 0,03250373 0,11662806 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03250373 0,11644639 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03250373 0,11626529 ! male sex determination GO:0030238 9 6 0,000 0,03250373 0,11608476 ! carnitine transport GO:0015879 8 6 0,000 0,03250373 0,11590478 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03250373 0,11572536 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03250373 0,1155465 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03250373 0,11536819 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03250373 0,11519042 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03250373 0,11501321 ! parturition GO:0007567 12 6 0,000 0,03250373 0,11483653 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03250373 0,11466041 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03250373 0,11448482 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03250373 0,11430976 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03250373 0,11413524 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03250373 0,11396126 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03250373 0,1137878 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03250373 0,11361487 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03250373 0,11344246 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03250373 0,11327058 ! astrocyte development GO:0014002 14 6 0,000 0,03250373 0,11309922 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03250373 0,11292838 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03250373 0,11275805 ! interaction with symbiont GO:0051702 8 6 0,000 0,03250373 0,11258823 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03250373 0,11241892 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03250373 0,11225013 ! eating behavior GO:0042755 6 6 0,000 0,03250373 0,11208184 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03250373 0,11191405 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03250373 0,11174676 ! response to copper ion GO:0046688 9 6 0,000 0,03250373 0,11157998 ! DNA topological change GO:0006265 8 6 0,000 0,03250373 0,11141369 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03250373 0,11124789 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03250373 0,11108259 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03250373 0,11091778 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03250373 0,11075346 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03250373 0,11058962 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03250373 0,11042627 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03250373 0,1102634 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03250373 0,11010101 ! gas homeostasis GO:0033483 11 6 0,000 0,03250373 0,10993909 ! hair follicle maturation GO:0048820 7 6 0,000 0,03250373 0,10977766 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03250373 0,10961669 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03250373 0,1094562 ! Schwann cell development GO:0014044 14 6 0,000 0,03250373 0,10929618 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03250373 0,10913662 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03250373 0,10897753 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03250373 0,1088189 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03250373 0,10866073 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03250373 0,10850303 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03250373 0,10834577 ! histone ubiquitination GO:0016574 7 6 0,000 0,03250373 0,10818898 ! regulation of meiosis GO:0040020 10 6 0,000 0,03250373 0,10803264 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03250373 0,10787674 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03250373 0,1077213 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03250373 0,10756631 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03250373 0,10741176 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03250373 0,10725765 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03250373 0,10710399 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03250373 0,10695076 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03250373 0,10679798 ! receptor internalization GO:0031623 9 6 0,000 0,03250373 0,10664563 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03250373 0,10649371 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03250373 0,10634223 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03250373 0,10619117 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03250373 0,10604055 ! protein deubiquitination GO:0016579 8 6 0,000 0,03250373 0,10589035 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03250373 0,10574057 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03250373 0,10559122 ! axonal fasciculation GO:0007413 9 6 0,000 0,03250373 0,10544229 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03250373 0,10529378 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03250373 0,10514569 ! midbrain development GO:0030901 6 6 0,000 0,03250373 0,10499801 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03250373 0,10485075 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03250373 0,1047039 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03250373 0,10455746 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03250373 0,10441143 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03250373 0,10426581 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03250373 0,10412059 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03250373 0,10397578 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03250373 0,10383137 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03250373 0,10368736 ! adult feeding behavior GO:0008343 6 6 0,000 0,03250373 0,10354375 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03250373 0,10340053 ! blastocyst growth GO:0001832 15 6 0,000 0,03250373 0,10325771 ! pigment granule transport GO:0051904 12 6 0,000 0,03250373 0,10311529 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03250373 0,10297326 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03250373 0,10283162 ! catecholamine transport GO:0051937 7 6 0,000 0,03250373 0,10269036 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03250373 0,1025495 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03250373 0,10240902 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03250373 0,10226893 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03250373 0,10212921 ! protein prenylation GO:0018342 10 6 0,000 0,03250373 0,10198988 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03250373 0,10185093 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03250373 0,10171236 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03250373 0,10157416 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03250373 0,10143634 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,03312715 0,10324179 ! aging GO:0007568 79 52 1,000 0,03312715 0,10310209 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,03312715 0,10296276 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,03430541 0,10648101 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,03549984 0,11003995 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,03549984 0,10989184 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,03549984 0,10974414 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03781843 0,11675488 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03781843 0,11659837 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03781843 0,11644229 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03781843 0,11628661 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03781843 0,11613136 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03781843 0,11597652 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03781843 0,11582209 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03781843 0,11566807 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03781843 0,11551446 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03781843 0,11536126 ! reproductive behavior GO:0019098 12 7 0,000 0,03781843 0,11520846 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03781843 0,11505607 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03781843 0,11490408 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03781843 0,11475249 ! oligopeptide transport GO:0006857 11 7 0,000 0,03781843 0,1146013 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03781843 0,11445051 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03781843 0,11430011 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03781843 0,11415011 ! RNA methylation GO:0001510 11 7 0,000 0,03781843 0,11400051 ! pericardium development GO:0060039 8 7 0,000 0,03781843 0,11385129 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03781843 0,11370247 ! fibril organization GO:0043206 13 7 0,000 0,03781843 0,11355403 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03781843 0,11340598 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03781843 0,11325832 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03781843 0,11311104 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03781843 0,11296414 ! lipoprotein transport GO:0042953 9 7 0,000 0,03781843 0,11281762 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03781843 0,11267149 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03781843 0,11252573 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03781843 0,11238034 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03781843 0,11223534 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03781843 0,1120907 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03781843 0,11194644 ! chemosensory behavior GO:0007635 9 7 0,000 0,03781843 0,11180255 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03781843 0,11165903 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03781843 0,11151588 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03781843 0,11137309 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03781843 0,11123067 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03781843 0,11108862 ! reflex GO:0060004 12 7 0,000 0,03781843 0,11094692 ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03781843 0,11080559 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03781843 0,11066461 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03781843 0,110524 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03781843 0,11038374 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03781843 0,11024384 ! spinal cord patterning GO:0021511 7 7 0,000 0,03781843 0,11010429 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03781843 0,10996509 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03781843 0,10982625 ! adrenal gland development GO:0030325 17 7 0,000 0,03781843 0,10968775 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03781843 0,10954961 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03781843 0,10941181 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03781843 0,10927436 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03781843 0,10913725 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03781843 0,10900048 ! endosome organization GO:0007032 10 7 0,000 0,03781843 0,10886406 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03781843 0,10872798 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03781843 0,10859224 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03781843 0,10845684 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03781843 0,10832178 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03781843 0,10818705 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03781843 0,10805265 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03781843 0,10791859 ! galactose metabolic process GO:0006012 10 7 0,000 0,03781843 0,10778487 ! vesicle fusion GO:0006906 15 7 0,000 0,03781843 0,10765147 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03781843 0,1075184 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03781843 0,10738566 ! organ growth GO:0035265 11 7 0,000 0,03781843 0,10725325 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03781843 0,10712117 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03781843 0,10698941 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03781843 0,10685797 ! retinol metabolic process GO:0042572 9 7 0,000 0,03781843 0,10672686 ! behavioral fear response GO:0001662 13 7 0,000 0,03781843 0,10659606 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03781843 0,10646559 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03781843 0,10633544 ! rRNA modification GO:0000154 12 7 0,000 0,03781843 0,1062056 ! protein heterooligomerization GO:0051291 10 7 0,000 0,03781843 0,10607608 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03781843 0,10594688 ! response to UV-B GO:0010224 11 7 0,000 0,03781843 0,10581799 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03781843 0,10568941 ! intermediate filament organization GO:0045109 11 7 0,000 0,03781843 0,10556115 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03781843 0,1054332 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03781843 0,10530555 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03781843 0,10517822 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03781843 0,10505119 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03781843 0,10492447 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03781843 0,10479806 ! response to tropane GO:0014073 13 7 0,000 0,03781843 0,10467195 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03781843 0,10454614 ! melanosome localization GO:0032400 10 7 0,000 0,03781843 0,10442063 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03781843 0,10429543 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03781843 0,10417052 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03781843 0,10404592 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03781843 0,10392161 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03781843 0,1037976 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03781843 0,10367388 ! mast cell activation GO:0045576 9 7 0,000 0,03781843 0,10355046 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03781843 0,10342733 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03781843 0,1033045 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03781843 0,10318195 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03781843 0,1030597 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03781843 0,10293774 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03781843 0,10281606 ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03781843 0,10269467 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03781843 0,10257357 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03781843 0,10245275 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03781843 0,10233222 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03781843 0,10221197 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03781843 0,102092 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03781843 0,10197232 ! diuresis GO:0030146 12 7 0,000 0,03781843 0,10185291 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03781843 0,10173379 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03781843 0,10161494 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03781843 0,10149637 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03781843 0,10137807 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03781843 0,10126005 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03781843 0,10114231 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03781843 0,10102484 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03781843 0,10090764 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03781843 0,10079071 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03781843 0,10067406 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03781843 0,10055767 ! lymph node development GO:0048535 9 7 0,000 0,03781843 0,10044156 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03781843 0,10032571 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03781843 0,10021012 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03781843 0,10009481 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03781843 0,09997976 ! ATP catabolic process GO:0006200 10 7 0,000 0,03781843 0,09986497 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03781843 0,09975044 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03781843 0,09963618 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03781843 0,09952218 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03781843 0,09940844 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03781843 0,09929496 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03781843 0,09918174 ! muscle adaptation GO:0043500 12 7 0,000 0,03781843 0,09906878 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03781843 0,09895607 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03781843 0,09884362 ! retina homeostasis GO:0001895 9 7 0,000 0,03781843 0,09873143 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03781843 0,09861949 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03781843 0,0985078 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03781843 0,09839637 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03781843 0,09828518 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03781843 0,09817425 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,03793643 0,09836955 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,03793643 0,09825877 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,03917817 0,10136083 GO:0048609|reproductive process in a multicellular organism, ! developmental maturation GO:0021700 75 57 1,000 0,03917817 0,10124695 ! gonad development GO:0008406 79 57 1,000 0,03917817 0,10113331 ! activation of MAPK activity GO:0000187 84 59 1,000 0,0417075 0,10754177 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,0429947 0,11073663 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,0429947 0,11061276 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04310423 0,11077066 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04310423 0,11064703 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,04310423 0,11052368 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04310423 0,1104006 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04310423 0,11027779 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04310423 0,11015526 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04310423 0,110033 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04310423 0,10991102 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04310423 0,1097893 ! phosphate transport GO:0006817 10 8 0,000 0,04310423 0,10966785 ! N-glycan processing GO:0006491 12 8 0,000 0,04310423 0,10954667 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04310423 0,10942576 ! UTP metabolic process GO:0046051 8 8 0,000 0,04310423 0,10930511 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04310423 0,10918473 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04310423 0,10906462 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04310423 0,10894477 ! succinate metabolic process GO:0006105 14 8 0,000 0,04310423 0,10882518 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,04310423 0,10870585 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04310423 0,10858679 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04310423 0,10846798 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,04310423 0,10834944 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04310423 0,10823115 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,04310423 0,10811313 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04310423 0,10799536 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04310423 0,10787784 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04310423 0,10776058 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04310423 0,10764358 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04310423 0,10752683 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04310423 0,10741033 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04310423 0,10729409 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04310423 0,10717809 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04310423 0,10706235 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04310423 0,10694686 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04310423 0,10683161 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04310423 0,10671662 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04310423 0,10660187 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04310423 0,10648737 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04310423 0,10637311 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04310423 0,1062591 ! melanin metabolic process GO:0006582 12 8 0,000 0,04310423 0,10614533 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04310423 0,1060318 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04310423 0,10591852 ! macrophage activation GO:0042116 12 8 0,000 0,04310423 0,10580548 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04310423 0,10569268 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04310423 0,10558012 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04310423 0,10546781 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04310423 0,10535572 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04310423 0,10524388 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04310423 0,10513228 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04310423 0,10502091 ! ruffle organization GO:0031529 11 8 0,000 0,04310423 0,10490977 ! osteoblast development GO:0002076 13 8 0,000 0,04310423 0,10479888 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04310423 0,10468821 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04310423 0,10457778 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04310423 0,10446758 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04310423 0,10435762 GO:0007351|tripartite regional subdivision, ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04310423 0,10424788 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04310423 0,10413838 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04310423 0,1040291 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04310423 0,10392006 ! brain morphogenesis GO:0048854 20 8 0,000 0,04310423 0,10381124 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04310423 0,10370265 ! segment specification GO:0007379 10 8 0,000 0,04310423 0,10359429 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04310423 0,10348616 ! cellular extravasation GO:0045123 11 8 0,000 0,04310423 0,10337824 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04310423 0,10327056 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04310423 0,1031631 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04310423 0,10305586 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,04310423 0,10294884 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04310423 0,10284205 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04310423 0,10273548 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04310423 0,10262913 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04310423 0,102523 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04310423 0,10241708 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04310423 0,10231139 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04310423 0,10220591 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04310423 0,10210066 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04310423 0,10199561 ! icosanoid secretion GO:0032309 12 8 0,000 0,04310423 0,10189079 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04310423 0,10178618 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04310423 0,10168178 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04310423 0,1015776 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04310423 0,10147363 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04310423 0,10136987 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04310423 0,10126633 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04310423 0,101163 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04310423 0,10105987 ! sterol catabolic process GO:0016127 9 8 0,000 0,04310423 0,10095696 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04310423 0,10085426 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04310423 0,10075177 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04310423 0,10064948 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04310423 0,1005474 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04310423 0,10044553 ! prophase GO:0051324 11 8 0,000 0,04310423 0,10034386 ! S phase GO:0051320 8 8 0,000 0,04310423 0,1002424 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04310423 0,10014115 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04310423 0,1000401 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04310423 0,09993925 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04310423 0,09983861 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04310423 0,09973817 ! hormone catabolic process GO:0042447 13 8 0,000 0,04310423 0,09963793 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04310423 0,09953789 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04310423 0,09943805 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04310423 0,09933841 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04310423 0,09923898 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04310423 0,09913974 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,04310423 0,0990407 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04310423 0,09894185 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04310423 0,09884321 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04310423 0,09874476 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04310423 0,0986465 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04310423 0,09854845 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04310423 0,09845058 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04310423 0,09835291 ! mitochondrion localization GO:0051646 12 8 0,000 0,04310423 0,09825544 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,04429665 0,10087356 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,04561316 0,10376881 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,04694403 0,10669098 GO:0090046|regulation of transcription regulator activity, ! regulation of lipase activity GO:0060191 109 63 1,000 0,04694403 0,10658566 ! appendage morphogenesis GO:0035107 93 64 1,000 0,04828907 0,10953142 GO:0035108|limb morphogenesis, ! adaptive immune response GO:0002250 94 64 1,000 0,04828907 0,10942351 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0483613 0,10947932 ! regulation of developmental growth GO:0048638 13 9 0,000 0,0483613 0,10937167 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,0483613 0,10926424 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0483613 0,10915701 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,0483613 0,10904999 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,0483613 0,10894318 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,0483613 0,10883659 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,0483613 0,1087302 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0483613 0,10862402 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,0483613 0,10851804 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,0483613 0,10841227 ! GTP metabolic process GO:0046039 9 9 0,000 0,0483613 0,10830671 ! elastic fiber assembly GO:0048251 13 9 0,000 0,0483613 0,10820135 ! social behavior GO:0035176 14 9 0,000 0,0483613 0,1080962 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,0483613 0,10799125 ! artery development GO:0060840 19 9 0,000 0,0483613 0,10788651 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,0483613 0,10778197 ! regulation of glycolysis GO:0006110 15 9 0,000 0,0483613 0,10767763 ! response to pain GO:0048265 16 9 0,000 0,0483613 0,10757349 ! protein complex disassembly GO:0043241 17 9 0,000 0,0483613 0,10746956 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0483613 0,10736582 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0483613 0,10726229 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,0483613 0,10715895 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0483613 0,10705581 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,0483613 0,10695288 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0483613 0,10685014 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0483613 0,10674759 ! protein targeting to ER GO:0045047 19 9 0,000 0,0483613 0,10664525 ! endoderm development GO:0007492 12 9 0,000 0,0483613 0,1065431 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0483613 0,10644114 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0483613 0,10633938 ! arginine catabolic process GO:0006527 10 9 0,000 0,0483613 0,10623781 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,0483613 0,10613644 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,0483613 0,10603526 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,0483613 0,10593428 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0483613 0,10583348 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,0483613 0,10573288 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,0483613 0,10563247 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,0483613 0,10553225 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,0483613 0,10543222 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0483613 0,10533238 ! mannose metabolic process GO:0006013 9 9 0,000 0,0483613 0,10523273 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,0483613 0,10513326 ! receptor clustering GO:0043113 15 9 0,000 0,0483613 0,10503399 ! epithelial cell development GO:0002064 10 9 0,000 0,0483613 0,1049349 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,0483613 0,104836 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0483613 0,10473728 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,0483613 0,10463875 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0483613 0,10454041 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,0483613 0,10444225 ! motor axon guidance GO:0008045 14 9 0,000 0,0483613 0,10434427 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,0483613 0,10424648 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,0483613 0,10414887 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,0483613 0,10405144 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,0483613 0,1039542 ! blastoderm segmentation GO:0007350 11 9 0,000 0,0483613 0,10385714 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0483613 0,10376025 ! DNA ligation GO:0006266 14 9 0,000 0,0483613 0,10366355 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,0483613 0,10356703 ! response to amine stimulus GO:0014075 13 9 0,000 0,0483613 0,10347069 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,0483613 0,10337453 ! erythrocyte development GO:0048821 11 9 0,000 0,0483613 0,10327854 ! renal water homeostasis GO:0003091 14 9 0,000 0,0483613 0,10318274 ! postreplication repair GO:0006301 11 9 0,000 0,0483613 0,10308711 ! mRNA cleavage GO:0006379 13 9 0,000 0,0483613 0,10299166 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,0483613 0,10289638 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,0483613 0,10280129 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,0483613 0,10270636 ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,0483613 0,10261162 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,0483613 0,10251704 ! acid secretion GO:0046717 14 9 0,000 0,0483613 0,10242264 ! musculoskeletal movement GO:0050881 11 9 0,000 0,0483613 0,10232842 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,0483613 0,10223437 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,0483613 0,10214049 ! purine base metabolic process GO:0006144 18 9 0,000 0,0483613 0,10204678 ! oocyte differentiation GO:0009994 12 9 0,000 0,0483613 0,10195325 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,0483613 0,10185988 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,0483613 0,10176669 ! spleen development GO:0048536 15 9 0,000 0,0483613 0,10167367 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,0483613 0,10158081 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,0483613 0,10148813 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,0483613 0,10139562 ! detection of calcium ion GO:0005513 13 9 0,000 0,0483613 0,10130327 ! blastocyst formation GO:0001825 12 9 0,000 0,0483613 0,10121109 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0483613 0,10111908 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,0483613 0,10102724 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,0483613 0,10093556 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0483613 0,10084405 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0483613 0,10075271 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,0483613 0,10066153 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,0483613 0,10057052 ! prepulse inhibition GO:0060134 14 9 0,000 0,0483613 0,10047967 ! embryonic placenta development GO:0001892 12 9 0,000 0,0483613 0,10038898 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,0483613 0,10029846 ! insulin secretion GO:0030073 17 9 0,000 0,0483613 0,1002081 ! sequestering of metal ion GO:0051238 11 9 0,000 0,0483613 0,1001179 ! response to nicotine GO:0035094 16 9 0,000 0,0483613 0,10002787 ! establishment of cell polarity GO:0030010 12 9 0,000 0,0483613 0,099938 ! regulation of synapse organization GO:0050807 12 9 0,000 0,0483613 0,09984829 ! reproductive structure development GO:0048608 90 65 1,000 0,04964808 0,10241309 ! appendage development GO:0048736 94 65 1,000 0,04964808 0,10232132 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 1,000 0,04964808 0,10222972 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,04964808 0,10213828 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,04964808 0,102047 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,04964808 0,10195589 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,04964808 0,10186494 ! activation of immune response GO:0002253 83 65 1,000 0,04964808 0,10177415 ! regulation of immune effector process GO:0002697 101 66 1,000 0,05102088 0,10449513 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 1,000 0,05240728 0,1072391 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05358979 0,10956134 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05358979 0,10946404 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05358979 0,10936691 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05358979 0,10926995 ! thyroid gland development GO:0030878 19 10 0,000 0,05358979 0,10917317 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05358979 0,10907655 ! synapsis GO:0007129 13 10 0,000 0,05358979 0,10898011 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05358979 0,10888384 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05358979 0,10878774 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05358979 0,1086918 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05358979 0,10859604 ! sulfate transport GO:0008272 12 10 0,000 0,05358979 0,10850045 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05358979 0,10840502 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,05358979 0,10830976 ! phospholipid efflux GO:0033700 16 10 0,000 0,05358979 0,10821467 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,05358979 0,10811974 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05358979 0,10802498 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05358979 0,10793039 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05358979 0,10783596 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05358979 0,1077417 ! pathogenesis GO:0009405 13 10 0,000 0,05358979 0,1076476 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05358979 0,10755367 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05358979 0,1074599 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05358979 0,1073663 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,05358979 0,10727285 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05358979 0,10717957 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05358979 0,10708645 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05358979 0,1069935 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05358979 0,1069007 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05358979 0,10680806 ! B cell proliferation GO:0042100 14 10 0,000 0,05358979 0,10671559 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05358979 0,10662328 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05358979 0,10653112 ! forebrain cell migration GO:0021885 17 10 0,000 0,05358979 0,10643912 ! lipid digestion GO:0044241 15 10 0,000 0,05358979 0,10634729 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05358979 0,10625561 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05358979 0,10616409 ! UV protection GO:0009650 14 10 0,000 0,05358979 0,10607273 ! entry into host cell GO:0030260 20 10 0,000 0,05358979 0,10598152 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05358979 0,10589047 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05358979 0,10579958 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05358979 0,10570884 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05358979 0,10561826 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05358979 0,10552783 ! regulation of organ growth GO:0046620 11 10 0,000 0,05358979 0,10543756 ! response to dsRNA GO:0043331 18 10 0,000 0,05358979 0,10534744 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05358979 0,10525748 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05358979 0,10516767 ! embryonic axis specification GO:0000578 12 10 0,000 0,05358979 0,10507801 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05358979 0,10498851 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05358979 0,10489915 ! cranial nerve development GO:0021545 12 10 0,000 0,05358979 0,10480995 ! fucose catabolic process GO:0019317 16 10 0,000 0,05358979 0,10472091 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05358979 0,10463201 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05358979 0,10454326 ! protein sumoylation GO:0016925 12 10 0,000 0,05358979 0,10445467 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05358979 0,10436622 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05358979 0,10427792 ! zymogen activation GO:0031638 14 10 0,000 0,05358979 0,10418978 ! salivary gland development GO:0007431 22 10 0,000 0,05358979 0,10410178 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05358979 0,10401393 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05358979 0,10392623 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05358979 0,10383867 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05358979 0,10375127 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05358979 0,10366401 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05358979 0,1035769 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05358979 0,10348993 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05358979 0,10340311 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05358979 0,10331643 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05358979 0,10322991 ! detection of bacterium GO:0016045 10 10 0,000 0,05358979 0,10314352 ! embryonic gut development GO:0048566 11 10 0,000 0,05358979 0,10305728 ! activation of innate immune response GO:0002218 10 10 0,000 0,05358979 0,10297118 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05358979 0,10288523 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05358979 0,10279942 ! developmental induction GO:0031128 13 10 0,000 0,05358979 0,10271376 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,05358979 0,10262823 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05358979 0,10254285 ! cytosolic calcium ion homeostasis GO:0051480 107 68 1,000 0,05380709 0,10287306 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,05380709 0,10278762 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,05380709 0,10270232 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,05380709 0,10261716 ! rhythmic process GO:0048511 105 68 1,000 0,05380709 0,10253214 ! response to drug GO:0042493 108 69 1,000 0,05522011 0,10513763 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,05522011 0,10505067 ! eye development GO:0001654 111 70 1,000 0,05664618 0,10767456 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,05664618 0,10758565 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 1,000 0,05808511 0,11022752 ! rRNA transcription GO:0009303 17 11 0,000 0,05878984 0,11147291 ! respiratory burst GO:0045730 14 11 0,000 0,05878984 0,11138108 ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05878984 0,11128941 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05878984 0,11119789 ! virus-host interaction GO:0019048 17 11 0,000 0,05878984 0,11110652 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05878984 0,1110153 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05878984 0,11092423 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,05878984 0,11083331 ! mating GO:0007618 14 11 0,000 0,05878984 0,11074254 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05878984 0,11065191 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05878984 0,11056144 ! bone resorption GO:0045453 16 11 0,000 0,05878984 0,11047111 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05878984 0,11038093 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05878984 0,11029089 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05878984 0,11020101 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05878984 0,11011127 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05878984 0,11002167 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05878984 0,10993222 ! syncytium formation GO:0006949 15 11 0,000 0,05878984 0,10984292 ! plasma membrane organization GO:0007009 18 11 0,000 0,05878984 0,10975376 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05878984 0,10966475 ! focal adhesion formation GO:0048041 24 11 0,000 0,05878984 0,10957588 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05878984 0,10948715 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05878984 0,10939857 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05878984 0,10931013 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05878984 0,10922184 ! adult heart development GO:0007512 11 11 0,000 0,05878984 0,10913369 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05878984 0,10904567 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,05878984 0,1089578 ! temperature homeostasis GO:0001659 16 11 0,000 0,05878984 0,10887008 ! L-glutamate transport GO:0015813 16 11 0,000 0,05878984 0,10878249 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05878984 0,10869504 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05878984 0,10860774 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05878984 0,10852057 ! stem cell development GO:0048864 29 11 0,000 0,05878984 0,10843355 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05878984 0,10834666 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05878984 0,10825992 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05878984 0,10817331 ! vasoconstriction GO:0042310 15 11 0,000 0,05878984 0,10808684 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05878984 0,10800051 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05878984 0,10791431 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05878984 0,10782826 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05878984 0,10774234 ! ribosome assembly GO:0042255 13 11 0,000 0,05878984 0,10765656 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05878984 0,10757091 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05878984 0,1074854 ! chromatin silencing GO:0006342 19 11 0,000 0,05878984 0,10740003 ! nucleosome positioning GO:0016584 13 11 0,000 0,05878984 0,10731479 ! T cell homeostasis GO:0043029 20 11 0,000 0,05878984 0,10722969 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05878984 0,10714472 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05878984 0,10705989 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05878984 0,10697519 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05878984 0,10689062 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05878984 0,10680619 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05878984 0,10672189 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05878984 0,10663773 ! male genitalia development GO:0030539 13 11 0,000 0,05878984 0,10655369 ! cholesterol efflux GO:0033344 19 11 0,000 0,05878984 0,10646979 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05878984 0,10638602 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05878984 0,10630239 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05878984 0,10621888 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05878984 0,10613551 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05878984 0,10605226 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05878984 0,10596915 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,05878984 0,10588617 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,05878984 0,10580331 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05878984 0,10572059 ! lysogeny GO:0030069 18 11 0,000 0,05878984 0,105638 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05878984 0,10555553 ! acrosome reaction GO:0007340 13 11 0,000 0,05878984 0,10547319 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05878984 0,10539099 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,05953671 0,10664676 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 116 73 1,000 0,06100081 0,10918433 ! protein import into nucleus GO:0006606 118 74 1,000 0,06247723 0,11174 ! lactation GO:0007595 20 12 0,000 0,06396162 0,11430593 ! reproductive cellular process GO:0048610 14 12 0,000 0,06396162 0,11421718 ! tRNA modification GO:0006400 14 12 0,000 0,06396162 0,11412857 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06396162 0,1140401 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06396162 0,11395177 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,06396162 0,11386357 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06396162 0,11377551 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06396162 0,11368758 ! non-recombinational repair GO:0000726 19 12 0,000 0,06396162 0,11359979 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06396162 0,11351214 ! peroxisomal transport GO:0043574 21 12 0,000 0,06396162 0,11342462 ! cartilage condensation GO:0001502 18 12 0,000 0,06396162 0,11333723 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06396162 0,11324999 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06396162 0,11316287 ! heart looping GO:0001947 15 12 0,000 0,06396162 0,11307589 ! palate development GO:0060021 15 12 0,000 0,06396162 0,11298904 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06396162 0,11290233 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06396162 0,11281574 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06396162 0,1127293 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06396162 0,11264298 ! arginine metabolic process GO:0006525 13 12 0,000 0,06396162 0,11255679 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06396162 0,11247074 ! methionine metabolic process GO:0006555 13 12 0,000 0,06396162 0,11238482 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06396162 0,11229903 ! Golgi organization GO:0007030 18 12 0,000 0,06396162 0,11221337 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06396162 0,11212784 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06396162 0,11204245 ! monoamine transport GO:0015844 13 12 0,000 0,06396162 0,11195718 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06396162 0,11187204 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,06396162 0,11178703 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06396162 0,11170215 ! L-amino acid transport GO:0015807 20 12 0,000 0,06396162 0,1116174 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06396162 0,11153278 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06396162 0,11144828 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06396162 0,11136391 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06396162 0,11127968 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06396162 0,11119556 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06396162 0,11111158 ! cerebellum development GO:0021549 13 12 0,000 0,06396162 0,11102772 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06396162 0,11094399 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06396162 0,11086038 ! histone methylation GO:0016571 15 12 0,000 0,06396162 0,11077691 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06396162 0,11069355 ! gland morphogenesis GO:0022612 23 12 0,000 0,06396162 0,11061032 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06396162 0,11052722 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06396162 0,11044424 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06396162 0,11036139 ! intestinal absorption GO:0050892 19 12 0,000 0,06396162 0,11027866 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06396162 0,11019605 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06396162 0,11011357 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06396162 0,11003121 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06396162 0,10994898 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06396162 0,10986686 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06396162 0,10978487 ! response to cold GO:0009409 14 12 0,000 0,06396162 0,10970301 ! regulation of ligase activity GO:0051340 114 75 1,000 0,0639658 0,10962841 ! nuclear import GO:0051170 121 75 1,000 0,0639658 0,10954678 ! response to unfolded protein GO:0006986 99 76 1,000 0,06546633 0,11203315 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,06546633 0,11194985 ! regulation of protein transport GO:0051223 114 76 1,000 0,06546633 0,11186668 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 1,000 0,06697865 0,11436593 ! gland development GO:0048732 148 77 1,000 0,06697865 0,11428109 ! sex differentiation GO:0007548 105 77 1,000 0,06697865 0,11419637 ! protein ubiquitination GO:0016567 125 77 1,000 0,06697865 0,11411178 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06910528 0,11764777 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06910528 0,11756076 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06910528 0,11747387 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06910528 0,11738711 ! water transport GO:0006833 17 13 0,000 0,06910528 0,11730047 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06910528 0,11721397 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06910528 0,11712759 ! lipid localization GO:0010876 24 13 0,000 0,06910528 0,11704134 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06910528 0,11695522 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06910528 0,11686922 ! organelle fusion GO:0048284 28 13 0,000 0,06910528 0,11678335 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06910528 0,11669761 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06910528 0,11661199 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06910528 0,1165265 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06910528 0,11644113 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06910528 0,11635589 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06910528 0,11627077 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06910528 0,11618578 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06910528 0,11610091 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06910528 0,11601616 ! NAD metabolic process GO:0019674 21 13 0,000 0,06910528 0,11593154 ! exocrine system development GO:0035272 27 13 0,000 0,06910528 0,11584704 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06910528 0,11576267 ! bone mineralization GO:0030282 15 13 0,000 0,06910528 0,11567841 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06910528 0,11559428 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06910528 0,11551028 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06910528 0,11542639 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06910528 0,11534263 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06910528 0,11525899 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,06910528 0,11517546 ! genitalia development GO:0048806 15 13 0,000 0,06910528 0,11509206 ! cellular pigmentation GO:0033059 24 13 0,000 0,06910528 0,11500879 ! tissue regeneration GO:0042246 21 13 0,000 0,06910528 0,11492563 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06910528 0,11484259 ! cofactor transport GO:0051181 19 13 0,000 0,06910528 0,11475967 ! NADP metabolic process GO:0006739 18 13 0,000 0,06910528 0,11467687 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06910528 0,11459419 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06910528 0,11451163 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06910528 0,11442919 ! gas transport GO:0015669 18 13 0,000 0,06910528 0,11434686 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06910528 0,11426466 ! regulation of axon extension GO:0030516 23 13 0,000 0,06910528 0,11418257 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06910528 0,1141006 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06910528 0,11401875 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06910528 0,11393702 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06910528 0,1138554 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06910528 0,1137739 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06910528 0,11369252 ! protein localization in nucleus GO:0034504 133 80 1,000 0,0715847 0,1176875 ! regulation of GTPase activity GO:0043087 129 80 1,000 0,0715847 0,11760343 ! response to protein stimulus GO:0051789 111 81 1,000 0,07314251 0,12007692 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,07422096 0,1217605 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,07422096 0,12167371 ! superoxide anion generation GO:0042554 18 14 0,000 0,07422096 0,12158705 ! neuron maturation GO:0042551 21 14 0,000 0,07422096 0,12150051 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,07422096 0,12141409 ! myotube differentiation GO:0014902 21 14 0,000 0,07422096 0,1213278 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07422096 0,12124163 ! inositol metabolic process GO:0006020 20 14 0,000 0,07422096 0,12115558 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07422096 0,12106966 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07422096 0,12098385 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07422096 0,12089817 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07422096 0,12081261 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07422096 0,12072717 ! response to cAMP GO:0051591 19 14 0,000 0,07422096 0,12064185 ! startle response GO:0001964 21 14 0,000 0,07422096 0,12055665 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07422096 0,12047157 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07422096 0,12038661 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,07422096 0,12030177 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07422096 0,12021705 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07422096 0,12013245 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,07422096 0,12004797 ! glycine metabolic process GO:0006544 22 14 0,000 0,07422096 0,11996361 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,07422096 0,11987937 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,07422096 0,11979524 ! regulation of heart rate GO:0002027 23 14 0,000 0,07422096 0,11971123 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07422096 0,11962734 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07422096 0,11954357 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07422096 0,11945991 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07422096 0,11937637 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07422096 0,11929295 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07422096 0,11920965 ! axon cargo transport GO:0008088 27 14 0,000 0,07422096 0,11912646 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07422096 0,11904339 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07422096 0,11896043 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07422096 0,11887759 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07422096 0,11879486 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07422096 0,11871225 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07422096 0,11862975 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07422096 0,11854737 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07422096 0,1184651 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07422096 0,11838295 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,07422096 0,11830091 ! muscle maintenance GO:0046716 19 14 0,000 0,07422096 0,11821899 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07422096 0,11813717 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07422096 0,11805547 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07422096 0,11797389 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07422096 0,11789241 ! cell killing GO:0001906 20 14 0,000 0,07422096 0,11781105 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,07422096 0,1177298 ! cilium assembly GO:0042384 20 14 0,000 0,07422096 0,11764867 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07422096 0,11756764 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07930883 0,12554047 ! positive regulation of cell size GO:0045793 20 15 0,000 0,07930883 0,12545413 ! metencephalon development GO:0022037 19 15 0,000 0,07930883 0,1253679 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07930883 0,1252818 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07930883 0,12519581 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,07930883 0,12510995 ! skin development GO:0043588 25 15 0,000 0,07930883 0,12502419 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07930883 0,12493856 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,07930883 0,12485305 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07930883 0,12476765 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07930883 0,12468237 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07930883 0,1245972 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07930883 0,12451215 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07930883 0,12442722 ! adult walking behavior GO:0007628 25 15 0,000 0,07930883 0,1243424 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07930883 0,1242577 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07930883 0,12417311 ! myoblast differentiation GO:0045445 27 15 0,000 0,07930883 0,12408864 ! centrosome cycle GO:0007098 16 15 0,000 0,07930883 0,12400428 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07930883 0,12392004 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,07930883 0,12383591 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07930883 0,1237519 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07930883 0,123668 ! cerebral cortex development GO:0021987 29 15 0,000 0,07930883 0,12358421 ! response to osmotic stress GO:0006970 22 15 0,000 0,07930883 0,12350054 ! vesicle coating GO:0006901 25 15 0,000 0,07930883 0,12341698 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07930883 0,12333354 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,07930883 0,1232502 ! peptide secretion GO:0002790 27 15 0,000 0,07930883 0,12316698 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07930883 0,12308387 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07930883 0,12300088 ! neuron recognition GO:0008038 22 15 0,000 0,07930883 0,12291799 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,07930883 0,12283522 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07930883 0,12275256 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07930883 0,12267001 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07930883 0,12258757 ! biomineral formation GO:0031214 18 15 0,000 0,07930883 0,12250524 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07930883 0,12242302 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07930883 0,12234091 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07930883 0,12225891 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07930883 0,12217703 ! organic cation transport GO:0015695 19 15 0,000 0,07930883 0,12209525 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07930883 0,12201358 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07930883 0,12193202 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,07930883 0,12185057 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 19 15 0,000 0,07930883 0,12176923 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07930883 0,12168799 ! regulation of protein localization GO:0032880 132 85 1,000 0,07948162 0,12187182 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,08271365 0,1267431 GO:0060538|skeletal muscle organ development, ! protein secretion GO:0009306 27 16 0,000 0,08436902 0,12919357 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,08436902 0,12910761 ! hormone secretion GO:0046879 25 16 0,000 0,08436902 0,12902177 ! bone remodeling GO:0046849 24 16 0,000 0,08436902 0,12893604 ! endothelial cell migration GO:0043542 22 16 0,000 0,08436902 0,12885042 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08436902 0,12876492 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08436902 0,12867954 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08436902 0,12859426 ! glial cell development GO:0021782 24 16 0,000 0,08436902 0,1285091 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08436902 0,12842405 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,08436902 0,12833911 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08436902 0,12825429 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08436902 0,12816958 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,08436902 0,12808498 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,08436902 0,12800049 ! fructose metabolic process GO:0006000 20 16 0,000 0,08436902 0,12791611 ! regulation of protein binding GO:0043393 27 16 0,000 0,08436902 0,12783184 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08436902 0,12774769 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,08436902 0,12766364 ! protein export from nucleus GO:0006611 24 16 0,000 0,08436902 0,12757971 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08436902 0,12749589 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,08436902 0,12741217 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08436902 0,12732857 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08436902 0,12724507 ! oogenesis GO:0048477 23 16 0,000 0,08436902 0,12716169 ! neural crest cell migration GO:0001755 24 16 0,000 0,08436902 0,12707841 ! G1 phase GO:0051318 27 16 0,000 0,08436902 0,12699525 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,08436902 0,12691219 ! detection of biotic stimulus GO:0009595 19 16 0,000 0,08436902 0,12682924 ! steroid catabolic process GO:0006706 22 16 0,000 0,08436902 0,1267464 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,08436902 0,12666367 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,08436902 0,12658104 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,08436902 0,12649853 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08436902 0,12641612 ! sperm-egg recognition GO:0035036 16 16 0,000 0,08436902 0,12633381 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,08436902 0,12625162 ! nerve development GO:0021675 18 16 0,000 0,08436902 0,12616953 ! negative regulation of translation GO:0017148 22 16 0,000 0,08436902 0,12608755 ! reproductive developmental process GO:0003006 127 89 1,000 0,08598563 0,12842009 ! regulation of T cell activation GO:0050863 128 89 1,000 0,08598563 0,12833676 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,08763621 0,13071549 ! RNA localization GO:0006403 135 91 1,000 0,08929632 0,13310533 ! response to virus GO:0009615 122 91 1,000 0,08929632 0,13301912 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08940168 0,13308989 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08940168 0,1330038 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08940168 0,13291782 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,08940168 0,13283196 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08940168 0,13274621 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08940168 0,13266056 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08940168 0,13257503 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08940168 0,13248961 ! signal complex assembly GO:0007172 29 17 0,000 0,08940168 0,1324043 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08940168 0,1323191 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08940168 0,132234 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,08940168 0,13214902 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08940168 0,13206415 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,08940168 0,13197938 ! memory GO:0007613 25 17 0,000 0,08940168 0,13189472 ! keratinization GO:0031424 17 17 0,000 0,08940168 0,13181018 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08940168 0,13172574 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08940168 0,13164141 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08940168 0,13155718 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08940168 0,13147307 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,08940168 0,13138906 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08940168 0,13130516 ! vacuolar transport GO:0007034 24 17 0,000 0,08940168 0,13122136 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,08940168 0,13113768 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08940168 0,13105409 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08940168 0,13097062 ! membrane budding GO:0006900 29 17 0,000 0,08940168 0,13088725 ! heme metabolic process GO:0042168 27 17 0,000 0,08940168 0,13080399 ! actin filament bundle formation GO:0051017 26 17 0,000 0,08940168 0,13072084 ! neuromuscular junction development GO:0007528 23 17 0,000 0,08940168 0,13063779 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,08940168 0,13055484 ! body fluid secretion GO:0007589 27 17 0,000 0,08940168 0,130472 ! stem cell differentiation GO:0048863 36 17 0,000 0,08940168 0,13038927 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08940168 0,13030664 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08940168 0,13022411 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08940168 0,13014169 ! sensory perception of pain GO:0019233 23 17 0,000 0,08940168 0,13005938 ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08940168 0,12997716 ! synaptogenesis GO:0007416 24 17 0,000 0,08940168 0,12989506 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,08940168 0,12981305 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08940168 0,12973115 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08940168 0,12964935 ! cell-cell junction organization GO:0045216 25 17 0,000 0,08940168 0,12956766 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08940168 0,12948607 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08940168 0,12940458 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,0909658 0,13158574 ! positive regulation of immune response GO:0050778 121 92 1,000 0,0909658 0,13150304 ! DNA recombination GO:0006310 146 92 1,000 0,0909658 0,13142043 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,0926445 0,13376167 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,09440698 0,13622086 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,09440698 0,13613545 ! positive regulation of translation GO:0045727 28 18 0,000 0,09440698 0,13605016 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,09440698 0,13596496 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,09440698 0,13587988 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,09440698 0,1357949 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,09440698 0,13571003 ! cAMP metabolic process GO:0046058 33 18 0,000 0,09440698 0,13562526 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,09440698 0,1355406 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,09440698 0,13545605 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,09440698 0,1353716 ! axis specification GO:0009798 26 18 0,000 0,09440698 0,13528726 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,09440698 0,13520302 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,09440698 0,13511889 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,09440698 0,13503486 ! glutamine metabolic process GO:0006541 23 18 0,000 0,09440698 0,13495093 ! response to retinoic acid GO:0032526 25 18 0,000 0,09440698 0,13486711 ! pigmentation during development GO:0048066 31 18 0,000 0,09440698 0,13478339 ! central nervous system neuron development GO:0021954 30 18 0,000 0,09440698 0,13469978 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,09440698 0,13461627 ! fucose metabolic process GO:0006004 26 18 0,000 0,09440698 0,13453287 ! response to fungus GO:0009620 19 18 0,000 0,09440698 0,13444957 ! peptide cross-linking GO:0018149 31 18 0,000 0,09440698 0,13436637 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,09440698 0,13428327 ! heart process GO:0003015 27 18 0,000 0,09440698 0,13420028 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,09440698 0,13411739 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,09440698 0,1340346 ! visual learning GO:0008542 35 18 0,000 0,09440698 0,13395191 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,09440698 0,13386933 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,09440698 0,13378684 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,09440698 0,13370446 ! vitamin transport GO:0051180 24 18 0,000 0,09440698 0,13362218 ! hormone transport GO:0009914 27 18 0,000 0,09440698 0,13354001 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,09440698 0,13345793 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,09440698 0,13337595 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,09440698 0,13329408 ! cell-cell recognition GO:0009988 20 18 0,000 0,09440698 0,1332123 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,09440698 0,13313062 ! regulation of glucose import GO:0046324 21 18 0,000 0,09440698 0,13304905 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,09440698 0,13296757 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,09440698 0,1328862 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,09440698 0,13280492 ! regulation of binding GO:0051098 151 95 1,000 0,09602898 0,13500406 ! angiogenesis GO:0001525 149 95 1,000 0,09602898 0,13492159 ! in utero embryonic development GO:0001701 147 96 1,000 0,09773446 0,13723398 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,09773446 0,13715025 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,09938504 0,13938146 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,09938504 0,13929653 ! positive regulation of ossification GO:0045778 30 19 0,000 0,09938504 0,13921169 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,09938504 0,13912696 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,09938504 0,13904233 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,09938504 0,13895781 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,09938504 0,13887339 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,09938504 0,13878907 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,09938504 0,13870485 ! regeneration GO:0031099 32 19 0,000 0,09938504 0,13862074 ! response to alkaloid GO:0043279 32 19 0,000 0,09938504 0,13853673 ! sensory perception of taste GO:0050909 23 19 0,000 0,09938504 0,13845282 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,09938504 0,13836901 ! smooth muscle contraction GO:0006939 36 19 0,000 0,09938504 0,1382853 ! peroxisome organization GO:0007031 29 19 0,000 0,09938504 0,13820169 ! digestive system process GO:0022600 30 19 0,000 0,09938504 0,13811819 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,09938504 0,13803478 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,09938504 0,13795148 ! response to vitamin A GO:0033189 26 19 0,000 0,09938504 0,13786827 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,09938504 0,13778517 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,09938504 0,13770217 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,09938504 0,13761926 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,09938504 0,13753646 ! sex determination GO:0007530 29 19 0,000 0,09938504 0,13745376 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,09938504 0,13737115 ! plasma membrane fusion GO:0045026 23 19 0,000 0,09938504 0,13728865 ! cytolysis GO:0019835 20 19 0,000 0,09938504 0,13720624 ! renal system process GO:0003014 35 19 0,000 0,09938504 0,13712393 ! vasodilation GO:0042311 33 19 0,000 0,09938504 0,13704173 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,09938504 0,13695962 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,09938504 0,1368776 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,09938504 0,13679569 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,09938504 0,13671387 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,09938504 0,13663216 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,09938504 0,13655054 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,09938504 0,13646901 ! sarcomere organization GO:0045214 23 19 0,000 0,09938504 0,13638759 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,09938504 0,13630626 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,09938504 0,13622503 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,09938504 0,13614389 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,09938504 0,13606286 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,09938504 0,13598191 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,09938504 0,13590107 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,09938504 0,13582032 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,09938504 0,13573967 ! protein stabilization GO:0050821 26 19 0,000 0,09938504 0,13565911 ! calcium ion transport GO:0006816 167 99 1,000 0,10290214 0,14037658 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,10290214 0,14029337 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,10433603 0,14216402 ! iron ion transport GO:0006826 37 20 0,000 0,10433603 0,14207985 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,10433603 0,14199578 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,10433603 0,1419118 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,10433603 0,14182793 ! response to vitamin GO:0033273 29 20 0,000 0,10433603 0,14174416 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,10433603 0,14166049 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,10433603 0,14157691 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,10433603 0,14149343 ! response to ethanol GO:0045471 37 20 0,000 0,10433603 0,14141005 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,10433603 0,14132677 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,10433603 0,14124359 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,10433603 0,14116051 ! chromosome condensation GO:0030261 31 20 0,000 0,10433603 0,14107752 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,10433603 0,14099463 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,10433603 0,14091184 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,10433603 0,14082914 ! DNA modification GO:0006304 28 20 0,000 0,10433603 0,14074655 ! collagen fibril organization GO:0030199 45 20 0,000 0,10433603 0,14066405 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,10433603 0,14058164 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,10433603 0,14049933 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,10433603 0,14041712 ! collagen catabolic process GO:0030574 25 20 0,000 0,10433603 0,14033501 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,10433603 0,14025299 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,10433603 0,14017106 ! alditol metabolic process GO:0019400 24 20 0,000 0,10433603 0,14008924 ! actin filament-based movement GO:0030048 34 20 0,000 0,10433603 0,1400075 ! divalent metal ion transport GO:0070838 171 100 1,000 0,1046413 0,14033527 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,10926008 0,14644416 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,10926008 0,14635887 GO:0016444|somatic cell DNA recombination, ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,10926008 0,14627368 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,10926008 0,14618858 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,10926008 0,14610359 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,10926008 0,14601869 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,10926008 0,1459339 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,10926008 0,1458492 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,10926008 0,1457646 ! vesicle docking GO:0048278 27 21 0,000 0,10926008 0,1456801 ! phototransduction GO:0007602 25 21 0,000 0,10926008 0,1455957 ! dendrite development GO:0016358 35 21 0,000 0,10926008 0,14551139 ! visual behavior GO:0007632 39 21 0,000 0,10926008 0,14542718 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,10926008 0,14534307 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,10926008 0,14525906 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,10926008 0,14517514 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,10926008 0,14509132 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,10926008 0,1450076 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,10926008 0,14492398 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,10926008 0,14484045 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,10926008 0,14475701 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,10926008 0,14467368 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,10926008 0,14459043 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,10926008 0,14450729 ! fatty acid transport GO:0015908 30 21 0,000 0,10926008 0,14442424 ! platelet activation GO:0030168 28 21 0,000 0,10926008 0,14434128 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,10926008 0,14425842 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,10926008 0,14417566 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,10926008 0,14409299 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,10926008 0,14401041 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,10926008 0,14392793 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,10926008 0,14384555 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,10926008 0,14376326 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,10926008 0,14368106 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,10926008 0,14359896 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,10926008 0,14351695 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,10926008 0,14343503 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,10926008 0,14335321 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,11415733 0,1496932 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,11415733 0,1496079 ! viral genome replication GO:0019079 29 22 0,000 0,11415733 0,1495227 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,11415733 0,1494376 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,11415733 0,1493526 ! molting cycle process GO:0022404 40 22 0,000 0,11415733 0,14926769 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,11415733 0,14918288 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,11415733 0,14909817 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,11415733 0,14901355 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,11415733 0,14892902 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,11415733 0,1488446 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,11415733 0,14876027 GO:0010810|regulation of cell-substrate adhesion, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,11415733 0,14867603 ! lysosome organization GO:0007040 37 22 0,000 0,11415733 0,14859189 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,11415733 0,14850784 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,11415733 0,14842389 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,11415733 0,14834004 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,11415733 0,14825628 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,11415733 0,14817261 ! membrane depolarization GO:0051899 35 22 0,000 0,11415733 0,14808904 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,11415733 0,14800556 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,11415733 0,14792218 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,11415733 0,14783889 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,11415733 0,14775569 ! blastocyst development GO:0001824 37 22 0,000 0,11415733 0,14767259 ! neural tube closure GO:0001843 33 22 0,000 0,11415733 0,14758958 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,11415733 0,14750667 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,11902795 0,1537138 ! embryonic pattern specification GO:0009880 31 23 0,000 0,11902795 0,15362754 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,11902795 0,15354138 ! myelination GO:0042552 35 23 0,000 0,11902795 0,15345531 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,11902795 0,15336934 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,11902795 0,15328347 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,11902795 0,15319769 ! vesicle targeting GO:0006903 32 23 0,000 0,11902795 0,15311201 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,11902795 0,15302643 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,11902795 0,15294094 ! osteoblast differentiation GO:0001649 40 23 0,000 0,11902795 0,15285554 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,11902795 0,15277024 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,11902795 0,15268504 ! interaction with host GO:0051701 37 23 0,000 0,11902795 0,15259993 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,11902795 0,15251492 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,11902795 0,15243 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,11902795 0,15234517 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,11902795 0,15226044 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,11902795 0,15217581 ! pentose metabolic process GO:0019321 31 23 0,000 0,11902795 0,15209127 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,11902795 0,15200682 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,11902795 0,15192246 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,11902795 0,1518382 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,11902795 0,15175403 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,11902795 0,15166996 ! telomere organization GO:0032200 32 23 0,000 0,11902795 0,15158598 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,11902795 0,15150209 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,11902795 0,1514183 ! regulation of amine transport GO:0051952 38 23 0,000 0,11902795 0,15133459 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,12387206 0,15740648 ! initiation of viral infection GO:0019059 42 24 0,000 0,12387206 0,15731956 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,12387206 0,15723274 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,12387206 0,15714602 ! superoxide metabolic process GO:0006801 32 24 0,000 0,12387206 0,15705939 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,12387206 0,15697285 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,12387206 0,15688642 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,12387206 0,15680007 ! sperm motility GO:0030317 27 24 0,000 0,12387206 0,15671382 ! vacuole organization GO:0007033 39 24 0,000 0,12387206 0,15662767 ! receptor metabolic process GO:0043112 37 24 0,000 0,12387206 0,15654161 ! neural crest cell development GO:0014032 39 24 0,000 0,12387206 0,15645565 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,12387206 0,15636978 ! primary neural tube formation GO:0014020 35 24 0,000 0,12387206 0,156284 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,12387206 0,15619832 ! glutathione metabolic process GO:0006749 29 24 0,000 0,12387206 0,15611273 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,12387206 0,15602723 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,12387206 0,15594183 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,12387206 0,15585653 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,12868981 0,16182972 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,12868981 0,16174129 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,12868981 0,16165295 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,12868981 0,16156471 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,12868981 0,16147657 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,12868981 0,16138853 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,12868981 0,16130058 ! peptide transport GO:0015833 43 25 0,000 0,12868981 0,16121272 ! male gonad development GO:0008584 33 25 0,000 0,12868981 0,16112496 ! iron ion homeostasis GO:0055072 39 25 0,000 0,12868981 0,1610373 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,12868981 0,16094973 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,12868981 0,16086226 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,12868981 0,16077488 ! phospholipid transport GO:0015914 35 25 0,000 0,12868981 0,1606876 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,12868981 0,16060041 ! detection of light stimulus GO:0009583 30 25 0,000 0,12868981 0,16051332 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,12868981 0,16042632 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,12868981 0,16033941 ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,12868981 0,1602526 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,13348134 0,16612937 ! translational initiation GO:0006413 43 26 0,000 0,13348134 0,16603952 ! circadian rhythm GO:0007623 42 26 0,000 0,13348134 0,16594977 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,13348134 0,16586012 ! post-embryonic development GO:0009791 42 26 0,000 0,13348134 0,16577056 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,13348134 0,1656811 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,13348134 0,16559174 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,13348134 0,16550247 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,13348134 0,1654133 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,13348134 0,16532422 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,13348134 0,16523524 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,13824679 0,1710423 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,13824679 0,17095034 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,13824679 0,17085848 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,13824679 0,17076672 ! membrane docking GO:0022406 39 27 0,000 0,13824679 0,17067506 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,13824679 0,17058349 ! catechol metabolic process GO:0009712 43 27 0,000 0,13824679 0,17049203 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,13824679 0,17040066 ! acute-phase response GO:0006953 42 27 0,000 0,13824679 0,17030939 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,13824679 0,17021822 ! myofibril assembly GO:0030239 36 27 0,000 0,13824679 0,17012714 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,13824679 0,17003616 ! lipid oxidation GO:0034440 38 27 0,000 0,13824679 0,16994528 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,13824679 0,1698545 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,13824679 0,16976382 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,13824679 0,16967323 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,13824679 0,16958274 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,13824679 0,16949234 ! gene silencing GO:0016458 41 27 0,000 0,13824679 0,16940204 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,14298631 0,17511636 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,14298631 0,17502316 ! phenol metabolic process GO:0018958 44 28 0,000 0,14298631 0,17493007 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,14298631 0,17483707 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,14298631 0,17474417 ! cell junction assembly GO:0034329 56 28 0,000 0,14298631 0,17465137 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,14298631 0,17455866 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,14298631 0,17446606 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,14298631 0,17437355 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,14298631 0,17428115 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,14298631 0,17418884 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,14298631 0,17409662 ! response to organic cyclic substance GO:0014070 47 28 0,000 0,14298631 0,17400451 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,14298631 0,17391249 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,14298631 0,17382057 ! mesoderm formation GO:0001707 46 28 0,000 0,14298631 0,17372875 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,14298631 0,17363702 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,14298631 0,17354539 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,14298631 0,17345386 ! ensheathment of neurons GO:0007272 43 28 0,000 0,14298631 0,17336243 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,14298631 0,17327109 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,14298631 0,17317984 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,14298631 0,1730887 ! neural tube formation GO:0001841 41 28 0,000 0,14298631 0,17299764 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,14298631 0,17290669 ! placenta development GO:0001890 37 28 0,000 0,14298631 0,17281583 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,14770004 0,17841916 ! regulation of innate immune response GO:0045088 38 29 0,000 0,14770004 0,1783255 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,14770004 0,17823194 ! mismatch repair GO:0006298 34 29 0,000 0,14770004 0,17813848 ! muscle cell development GO:0055001 38 29 0,000 0,14770004 0,17804512 ! formation of primary germ layer GO:0001704 48 29 0,000 0,14770004 0,17795185 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,14770004 0,17785868 ! eye morphogenesis GO:0048592 51 29 0,000 0,14770004 0,17776561 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,14770004 0,17767264 ! tissue homeostasis GO:0001894 42 29 0,000 0,14770004 0,17757976 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,1523881 0,1831205 ! collagen metabolic process GO:0032963 40 30 0,000 0,1523881 0,18302487 ! organic anion transport GO:0015711 51 30 0,000 0,1523881 0,18292935 ! cholesterol transport GO:0030301 46 30 0,000 0,1523881 0,18283392 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,1523881 0,1827386 ! spliceosome assembly GO:0000245 49 30 0,000 0,1523881 0,18264337 ! spindle organization GO:0007051 37 30 0,000 0,1523881 0,18254825 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,1523881 0,18245322 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,1523881 0,18235829 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,1523881 0,18226346 ! ceramide metabolic process GO:0006672 43 30 0,000 0,1523881 0,18216873 ! hindbrain development GO:0030902 45 30 0,000 0,1523881 0,1820741 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,1523881 0,18197956 ! adult locomotory behavior GO:0008344 47 30 0,000 0,1523881 0,18188512 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,1523881 0,18179079 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,1523881 0,18169654 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,1523881 0,1816024 ! response to heat GO:0009408 41 30 0,000 0,1523881 0,18150835 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,1523881 0,18141441 ! negative regulation of secretion GO:0051048 49 31 0,000 0,15705065 0,18686833 ! mammary gland development GO:0030879 57 31 0,000 0,15705065 0,18677171 ! glial cell differentiation GO:0010001 55 31 0,000 0,15705065 0,18667519 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,15705065 0,18657876 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,15705065 0,18648244 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,15705065 0,18638622 ! odontogenesis GO:0042476 50 31 0,000 0,15705065 0,18629009 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,15705065 0,18619407 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,15705065 0,18609814 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,15705065 0,18600231 ! metanephros development GO:0001656 58 31 0,000 0,15705065 0,18590658 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,15705065 0,18581095 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,15705065 0,18571542 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,15705065 0,18561998 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,15705065 0,18552465 ! RNA modification GO:0009451 40 31 0,000 0,15705065 0,18542941 ! regulation of muscle development GO:0048634 48 32 0,000 0,16168781 0,19080655 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,16168781 0,1907087 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,16168781 0,19061095 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,16168781 0,1905133 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,16168781 0,19041575 GO:0006639|acylglycerol metabolic process, ! peripheral nervous system development GO:0007422 53 32 0,000 0,16168781 0,1903183 ! regulation of protein stability GO:0031647 48 32 0,000 0,16168781 0,19022095 ! cytokine production GO:0001816 44 32 0,000 0,16168781 0,1901237 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,16168781 0,19002655 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,16168781 0,1899295 ! vesicle localization GO:0051648 47 32 0,000 0,16168781 0,18983255 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,16629973 0,19514764 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,16629973 0,19504813 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,16629973 0,19494871 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,16629973 0,1948494 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,16629973 0,19475019 ! sister chromatid segregation GO:0000819 46 33 0,000 0,16629973 0,19465108 ! ear morphogenesis GO:0042471 42 33 0,000 0,16629973 0,19455207 ! actomyosin structure organization GO:0031032 43 33 0,000 0,16629973 0,19445316 ! cell junction organization GO:0034330 63 33 0,000 0,16629973 0,19435436 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,16629973 0,19425565 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,16629973 0,19415704 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,16629973 0,19405854 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,16629973 0,19396013 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,16629973 0,19386182 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,16629973 0,19376361 ! positive regulation of cell development GO:0010720 54 33 0,000 0,16629973 0,19366551 ! lipid homeostasis GO:0055088 55 33 0,000 0,16629973 0,1935675 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,16629973 0,19346959 ! regulation of proteolysis GO:0030162 50 33 0,000 0,16629973 0,19337178 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,16629973 0,19327407 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,16629973 0,19317645 ! mRNA catabolic process GO:0006402 48 34 0,000 0,17088654 0,19840436 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,17088654 0,19830426 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,17088654 0,19820425 ! feeding behavior GO:0007631 45 34 0,000 0,17088654 0,19810435 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,17088654 0,19800455 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,17088654 0,19790485 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,17088654 0,19780525 ! neuron migration GO:0001764 46 34 0,000 0,17088654 0,19770575 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,17088654 0,19760635 ! female gamete generation GO:0007292 43 34 0,000 0,17088654 0,19750705 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,17088654 0,19740785 ! polyol metabolic process GO:0019751 44 34 0,000 0,17088654 0,19730875 ! aerobic respiration GO:0009060 47 34 0,000 0,17088654 0,19720975 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,17088654 0,19711085 ! embryonic organ development GO:0048568 45 34 0,000 0,17088654 0,19701205 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,17088654 0,19691334 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,17544837 0,20206873 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,17544837 0,2019676 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,17544837 0,20186656 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,17544837 0,20176563 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,17544837 0,2016648 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,17544837 0,20156406 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,17544837 0,20146343 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,17544837 0,2013629 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,17544837 0,20126247 ! glycogen metabolic process GO:0005977 48 35 0,000 0,17544837 0,20116214 ! pigment metabolic process GO:0042440 61 35 0,000 0,17544837 0,20106191 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,17998537 0,20615854 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,17998537 0,20605592 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,17998537 0,20595341 ! negative regulation of binding GO:0051100 58 36 0,000 0,17998537 0,20585099 ! organic ether metabolic process GO:0018904 46 36 0,000 0,17998537 0,20574868 ! neural tube development GO:0021915 50 36 0,000 0,17998537 0,20564647 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,17998537 0,20554436 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,17998537 0,20544235 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,17998537 0,20534045 ! glucan metabolic process GO:0044042 49 36 0,000 0,17998537 0,20523864 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,18449766 0,21027979 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,18449766 0,21017564 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,18449766 0,21007159 ! learning GO:0007612 67 37 0,000 0,18449766 0,20996764 ! ion transmembrane transport GO:0034220 56 37 0,000 0,18449766 0,2098638 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,18449766 0,20976006 ! regulation of protein secretion GO:0050708 51 37 0,000 0,18449766 0,20965643 ! amino acid activation GO:0043038 52 37 0,000 0,18449766 0,20955289 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,18449766 0,20944946 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,18898537 0,21443826 ! gliogenesis GO:0042063 71 38 0,000 0,18898537 0,21433252 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,18898537 0,21422689 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,18898537 0,21412136 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,18898537 0,21401593 ! phagocytosis GO:0006909 60 38 0,000 0,18898537 0,21391061 ! mesenchymal cell development GO:0014031 64 38 0,000 0,18898537 0,21380539 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,18898537 0,21370028 ! maintenance of location in cell GO:0051651 69 38 0,000 0,18898537 0,21359526 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,19344865 0,21853237 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,19344865 0,21842508 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,19344865 0,21831791 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,19344865 0,21821084 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,19344865 0,21810387 ! male sex differentiation GO:0046661 53 39 0,000 0,19344865 0,21799701 ! chromatin remodeling GO:0006338 68 39 0,000 0,19344865 0,21789025 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,19344865 0,2177836 ! developmental growth GO:0048589 62 39 0,000 0,19344865 0,21767705 ! cell growth GO:0016049 61 39 0,000 0,19344865 0,21757061 ! synapse organization GO:0050808 55 39 0,000 0,19344865 0,21746427 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,19788762 0,22234564 ! response to calcium ion GO:0051592 58 40 0,000 0,19788762 0,22223707 ! regulation of tube size GO:0035150 60 40 0,000 0,19788762 0,22212861 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,19788762 0,22202026 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,19788762 0,22191201 ! peptide metabolic process GO:0006518 56 40 0,000 0,19788762 0,22180386 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,19788762 0,22169582 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,19788762 0,22158789 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,19788762 0,22148006 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,19788762 0,22137234 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,19788762 0,22126472 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,20230241 0,22609113 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,20230241 0,22598132 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,20230241 0,22587162 ! glucose transport GO:0015758 52 41 0,000 0,20230241 0,22576203 ! endosome transport GO:0016197 71 41 0,000 0,20230241 0,22565254 ! striated muscle contraction GO:0006941 62 41 0,000 0,20230241 0,22554316 ! biopolymer methylation GO:0043414 62 41 0,000 0,20230241 0,22543389 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,20230241 0,22532472 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,20669315 0,23010371 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,20669315 0,22999238 ! cellular component disassembly GO:0022411 64 42 0,000 0,20669315 0,22988117 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,20669315 0,22977006 ! hexose transport GO:0008645 54 42 0,000 0,20669315 0,22965906 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,20669315 0,22954817 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,20669315 0,22943738 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,20669315 0,2293267 ! excretion GO:0007588 63 42 0,000 0,20669315 0,22921613 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,20669315 0,22910567 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,20669315 0,22899531 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,20669315 0,22888505 ! leukocyte migration GO:0050900 60 43 0,000 0,21105998 0,23360826 ! tRNA processing GO:0008033 49 43 0,000 0,21105998 0,23349589 ! vesicle organization GO:0016050 79 43 0,000 0,21105998 0,23338363 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,21105998 0,23327148 ! methylation GO:0032259 64 43 0,000 0,21105998 0,23315944 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,21540302 0,23784299 ! glycolysis GO:0006096 53 44 0,000 0,21540302 0,23772886 ! regulation of action potential GO:0001508 71 44 0,000 0,21540302 0,23761484 ! regulation of ion transport GO:0043269 57 44 0,000 0,21540302 0,23750093 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,21540302 0,23738713 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,21540302 0,23727344 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,21540302 0,23715986 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,21540302 0,23704639 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,21540302 0,23693302 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,21540302 0,23681976 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,21540302 0,23670661 ! RNA catabolic process GO:0006401 64 45 0,000 0,2197224 0,24133788 ! positive regulation of defense response GO:0031349 59 45 0,000 0,2197224 0,24122268 ! regulation of translational initiation GO:0006446 64 45 0,000 0,2197224 0,24110759 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,2197224 0,24099262 ! cell recognition GO:0008037 58 45 0,000 0,2197224 0,24087775 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,22401824 0,2454702 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,22401824 0,24535331 ! cell redox homeostasis GO:0045454 63 46 0,000 0,22401824 0,24523653 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,22401824 0,24511987 ! regulation of ossification GO:0030278 71 46 0,000 0,22401824 0,24500331 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,22829068 0,2495573 ! viral infectious cycle GO:0019058 71 47 0,000 0,22829068 0,24943875 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,22829068 0,24932031 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,22829068 0,24920198 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,22829068 0,24908376 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,22829068 0,24896566 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,22829068 0,24884766 ! chloride transport GO:0006821 67 48 0,000 0,23253984 0,25335937 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,23253984 0,25323941 ! response to temperature stimulus GO:0009266 62 48 0,000 0,23253984 0,25311956 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,23253984 0,25299983 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,23253984 0,25288021 ! gastrulation GO:0007369 73 48 0,000 0,23253984 0,2527607 ! heart morphogenesis GO:0003007 65 48 0,000 0,23253984 0,2526413 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,23253984 0,25252202 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,23253984 0,25240285 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,23253984 0,25228379 ! regulation of endocytosis GO:0030100 63 48 0,000 0,23253984 0,25216484 ! nuclear export GO:0051168 69 48 0,000 0,23253984 0,25204601 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,23253984 0,25192729 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,23676585 0,25638486 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,23676585 0,25626421 ! sensory perception of smell GO:0007608 61 49 0,000 0,23676585 0,25614367 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,23676585 0,25602325 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,23676585 0,25590294 ! RNA elongation GO:0006354 62 49 0,000 0,23676585 0,25578274 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,23676585 0,25566265 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,23676585 0,25554268 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,23676585 0,25542282 ! cartilage development GO:0051216 70 49 0,000 0,23676585 0,25530307 ! maintenance of location GO:0051235 84 49 0,000 0,23676585 0,25518343 ! regulation of actin filament length GO:0030832 72 50 0,000 0,24096882 0,25959171 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,24096882 0,25947017 ! membrane fusion GO:0006944 80 50 0,000 0,24096882 0,25934876 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,24096882 0,25922745 ! positive regulation of growth GO:0045927 67 50 0,000 0,24096882 0,25910626 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,24096882 0,25898518 ! proton transport GO:0015992 75 50 0,000 0,24096882 0,25886422 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,24096882 0,25874337 ! positive regulation of secretion GO:0051047 71 51 0,000 0,24514889 0,26310894 ! hydrogen transport GO:0006818 77 51 0,000 0,24514889 0,26298622 ! muscle fiber development GO:0048747 74 51 0,000 0,24514889 0,26286361 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,24514889 0,26274112 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,24514889 0,26261875 ! adult behavior GO:0030534 80 51 0,000 0,24514889 0,26249649 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,24514889 0,26237434 ! transition metal ion transport GO:0000041 74 52 0,000 0,24930618 0,26669964 ! regulation of cellular component size GO:0032535 74 52 0,000 0,24930618 0,26657565 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,24930618 0,26645177 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,25344081 0,27074495 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,25344081 0,27061925 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,25344081 0,27049367 ! kidney development GO:0001822 90 53 0,000 0,25344081 0,27036821 ! single fertilization GO:0007338 59 53 0,000 0,25344081 0,27024287 ! amino acid transport GO:0006865 84 54 0,000 0,25755291 0,27450032 ! glucose catabolic process GO:0006007 66 54 0,000 0,25755291 0,27437317 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,25755291 0,27424615 ! DNA catabolic process GO:0006308 67 54 0,000 0,25755291 0,27411924 ! detection of external stimulus GO:0009581 66 54 0,000 0,25755291 0,27399245 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,25755291 0,27386578 ! exocytosis GO:0006887 74 55 0,000 0,26164258 0,27808593 ! mesoderm development GO:0007498 76 55 0,000 0,26164258 0,27795748 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,26164258 0,27782915 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,26164258 0,27770094 ! carbohydrate transport GO:0008643 74 57 0,000 0,26975518 0,28617939 ! chromosome segregation GO:0007059 83 57 0,000 0,26975518 0,28604745 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,26975518 0,28591563 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,26975518 0,28578393 ! camera-type eye development GO:0043010 88 57 0,000 0,26975518 0,28565235 ! secondary metabolic process GO:0019748 84 57 0,000 0,26975518 0,2855209 ! viral reproductive process GO:0022415 87 58 0,000 0,27377834 0,28964589 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,27377834 0,28951272 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,27377834 0,28937968 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,27777956 0,29347404 ! actin filament organization GO:0007015 95 59 0,000 0,27777956 0,29333929 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,27777956 0,29320467 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,28175896 0,29726863 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,28175896 0,29713233 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,28175896 0,29699616 ! regulation of heart contraction GO:0008016 91 60 0,000 0,28175896 0,29686011 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,28175896 0,29672418 ! fertilization GO:0009566 68 60 0,000 0,28175896 0,29658838 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,28571667 0,3006168 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,28571667 0,30047935 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,28571667 0,30034202 ! urogenital system development GO:0001655 101 61 0,000 0,28571667 0,30020481 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,28571667 0,30006773 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,28571667 0,29993078 ! extracellular matrix organization GO:0030198 103 61 0,000 0,28571667 0,29979395 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,28571667 0,29965724 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! amine catabolic process GO:0009310 90 62 0,000 0,28965279 0,30364695 ! neurotransmitter transport GO:0006836 81 62 0,000 0,28965279 0,30350862 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,28965279 0,30337041 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,28965279 0,30323233 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,29356745 0,30719069 ! viral reproduction GO:0016032 92 63 0,000 0,29356745 0,30705099 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,29746076 0,3109817 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,29746076 0,31084041 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,29746076 0,31069925 ! hexose catabolic process GO:0019320 82 64 0,000 0,29746076 0,31055821 ! defense response to bacterium GO:0042742 73 65 0,000 0,30133283 0,31445803 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,30518378 0,31833229 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,30518378 0,31818799 ! antigen processing and presentation GO:0019882 96 66 0,000 0,30518378 0,31804381 ! axon guidance GO:0007411 99 66 0,000 0,30518378 0,31789977 ! acute inflammatory response GO:0002526 92 68 0,000 0,31282278 0,32570955 ! learning or memory GO:0007611 123 68 0,000 0,31282278 0,32556217 ! inorganic anion transport GO:0015698 93 68 0,000 0,31282278 0,32541493 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,31661106 0,3292068 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,31661106 0,32905804 ! response to metal ion GO:0010038 103 70 0,000 0,32037866 0,33282336 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,32037866 0,33267311 ! humoral immune response GO:0006959 86 70 0,000 0,32037866 0,33252298 ! amine transport GO:0015837 101 70 0,000 0,32037866 0,33237299 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,32037866 0,33222314 ! regulation of catabolic process GO:0009894 106 70 0,000 0,32037866 0,33207342 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,32412572 0,33580592 ! muscle cell differentiation GO:0042692 104 71 0,000 0,32412572 0,33565473 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,32412572 0,33550367 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,32412572 0,33535274 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,32412572 0,33520195 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,32785232 0,33890352 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,32785232 0,33875127 ! regulation of blood pressure GO:0008217 107 73 0,000 0,33155859 0,34242692 ! tube morphogenesis GO:0035239 118 73 0,000 0,33155859 0,34227323 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,33155859 0,34211968 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,33155859 0,34196626 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,33524464 0,34561303 ! digestion GO:0007586 97 74 0,000 0,33524464 0,34545818 ! response to inorganic substance GO:0010035 115 75 0,000 0,33891057 0,3490794 ! response to nutrient GO:0007584 104 75 0,000 0,33891057 0,34892315 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,33891057 0,34876703 ! amine biosynthetic process GO:0009309 97 76 0,000 0,34255649 0,35236133 ! tRNA metabolic process GO:0006399 95 76 0,000 0,34255649 0,35220381 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,34618252 0,35577292 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,34618252 0,35561402 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,34618252 0,35545526 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,34618252 0,35529665 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,34618252 0,35513817 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,34978875 0,35867772 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,34978875 0,35851788 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,34978875 0,35835818 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,3533753 0,36187141 ! cellular respiration GO:0045333 107 79 0,000 0,3533753 0,36171036 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,3533753 0,36154946 ! regulation of lyase activity GO:0051339 133 79 0,000 0,3533753 0,3613887 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,3533753 0,36122808 ! chromatin assembly GO:0031497 102 80 0,000 0,35694227 0,36471222 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,35694227 0,36455027 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,36048976 0,36800997 ! mRNA transport GO:0051028 121 81 0,000 0,36048976 0,3678467 ! regulation of neurological system process GO:0031644 122 81 0,000 0,36048976 0,36768357 ! vitamin metabolic process GO:0006766 103 81 0,000 0,36048976 0,36752059 ! detection of stimulus GO:0051606 108 82 0,000 0,36401789 0,3709531 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,36752676 0,37436295 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,36752676 0,37419723 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,36752676 0,37403166 ! regulation of defense response GO:0031347 117 84 0,000 0,37101647 0,37741613 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,37101647 0,37724928 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,37101647 0,37708258 ! sterol metabolic process GO:0016125 120 84 0,000 0,37101647 0,37691602 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,37448712 0,3802739 ! rRNA metabolic process GO:0016072 107 85 0,000 0,37448712 0,38010608 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,37448712 0,37993841 ! regulation of membrane potential GO:0042391 128 85 0,000 0,37448712 0,37977089 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,37793882 0,38310237 ! nucleosome organization GO:0034728 114 87 0,000 0,38137167 0,38641183 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,38137167 0,38624168 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,38137167 0,38607167 ! female pregnancy GO:0007565 130 87 0,000 0,38137167 0,38590182 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,38478577 0,38918526 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,38478577 0,38901419 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,38478577 0,38884327 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,38478577 0,3886725 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,38478577 0,38850188 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,38818123 0,39175815 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,38818123 0,39158633 ! hormone metabolic process GO:0042445 121 90 0,000 0,39155814 0,39481969 ! ATP metabolic process GO:0046034 137 91 0,000 0,39491661 0,39803164 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,39825672 0,40122228 ! sulfur metabolic process GO:0006790 118 92 0,000 0,39825672 0,40104661 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,4015786 0,40421478 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,4015786 0,40403796 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,4015786 0,40386129 ! electron transport chain GO:0022900 123 94 0,000 0,40488232 0,40700583 ! response to oxidative stress GO:0006979 141 94 0,000 0,40488232 0,40682802 ! carboxylic acid transport GO:0046942 147 95 0,000 0,40816799 0,40995039 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,41143572 0,41305201 ! protein maturation GO:0051604 129 96 0,000 0,41143572 0,41287179 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,41468558 0,41595152 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,41468558 0,4157702 ! extracellular structure organization GO:0043062 156 99 0,000 0,42113213 0,42204963 ! regulation of translation GO:0006417 151 100 0,000 0,42432901 0,42506826 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,42432901 0,42488321 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,42432901 0,42469831 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,42432901 0,42451358 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,42432901 0,42432901