pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/847-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 4,242E-07 1,021E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,599E-06 1,924E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 9,03E-06 7,242E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,711E-05 0,01029422 ! response to protozoan GO:0001562 10 5 1,000 2,377E-05 0,01143599 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 1,000 2,377E-05 9,53E-03 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 1,000 2,377E-05 8,169E-03 ! lymphocyte activation during immune response GO:0002285 9 5 1,000 2,377E-05 7,147E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 2,377E-05 6,353E-03 GO:0051930|regulation of sensory perception of pain, ! androgen receptor signaling pathway GO:0030521 74 36 2,000 2,453E-05 5,902E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 3,379E-05 7,391E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! chromatin-mediated maintenance of transcription GO:0048096 13 6 1,000 3,561E-05 7,14E-03 ! response to UV-C GO:0010225 11 6 1,000 3,561E-05 6,591E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 3,918E-05 6,733E-03 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 1,000 4,981E-05 7,989E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 4,981E-05 7,49E-03 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 1,000 4,981E-05 7,049E-03 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 4,981E-05 6,658E-03 ! regulation of interleukin-10 production GO:0032653 13 7 1,000 4,981E-05 6,307E-03 ! melanin biosynthetic process GO:0042438 8 7 1,000 4,981E-05 5,992E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 5,158E-05 5,91E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 6,635E-05 7,256E-03 ! melanin metabolic process GO:0006582 15 8 1,000 6,635E-05 6,94E-03 ! leukocyte activation during immune response GO:0002366 13 8 1,000 6,635E-05 6,651E-03 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 1,000 6,635E-05 6,385E-03 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 1,000 8,522E-05 7,886E-03 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 1,000 8,522E-05 7,594E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 8,522E-05 7,322E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 9,824E-05 8,15E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,064E-04 8,534E-03 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,064E-04 8,259E-03 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 1,299E-04 9,769E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,325E-04 9,657E-03 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 1,558E-04 0,01102252 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,558E-04 0,01070759 ! tyrosine metabolic process GO:0006570 16 12 1,000 1,558E-04 0,01041015 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 1,000 1,558E-04 0,0101288 ! regulation of interleukin-8 production GO:0032677 20 12 1,000 1,558E-04 9,862E-03 ! spleen development GO:0048536 22 12 1,000 1,558E-04 9,609E-03 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 1,000 1,558E-04 9,369E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,662E-04 9,756E-03 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 1,839E-04 0,01053486 ! positive regulation of homeostatic process GO:0032846 21 13 1,000 1,839E-04 0,01028986 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 1,839E-04 0,010056 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 2,471E-04 0,01320977 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,471E-04 0,01292261 ! positive regulation of calcium ion transport GO:0051928 19 15 1,000 2,471E-04 0,01264766 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 2,471E-04 0,01238416 ! positive regulation of ion transport GO:0043270 21 16 1,000 2,821E-04 0,01385069 ! startle response GO:0001964 28 16 1,000 2,821E-04 0,01357368 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,821E-04 0,01330753 ! regulation of protein transport GO:0051223 154 87 2,000 3,444E-04 0,01593433 GO:0070201|regulation of establishment of protein localization, ! positive regulation of translation GO:0045727 30 19 1,000 4,008E-04 0,01819324 ! pigmentation during development GO:0048066 41 19 1,000 4,008E-04 0,01785632 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 4,449E-04 0,01946025 ! regulation of protein localization GO:0032880 176 97 2,000 4,738E-04 0,0203581 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 4,912E-04 0,02073337 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 5,398E-04 0,02239121 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 5,398E-04 0,02201169 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 5,398E-04 0,02164483 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 6,436E-04 0,02538685 ! regulation of tumor necrosis factor production GO:0032680 34 24 1,000 6,436E-04 0,02497739 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 6,989E-04 0,02669183 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 7,564E-04 0,02843605 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 1,077E-03 0,03986087 ! pigment biosynthetic process GO:0046148 66 32 1,000 1,148E-03 0,04183246 ! regulation of calcium ion transport GO:0051924 53 32 1,000 1,148E-03 0,04120809 ! adult locomotory behavior GO:0008344 59 33 1,000 1,22E-03 0,04317865 ! maintenance of protein location in cell GO:0032507 86 36 1,000 1,452E-03 0,05062222 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 1,452E-03 0,04989904 ! establishment or maintenance of cell polarity GO:0007163 83 37 1,000 1,533E-03 0,05195582 ! pigment metabolic process GO:0042440 80 37 1,000 1,533E-03 0,05123421 ! regulation of metal ion transport GO:0010959 63 38 1,000 1,617E-03 0,05328678 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 1,617E-03 0,05256669 ! Rho protein signal transduction GO:0007266 74 39 1,000 1,702E-03 0,05461509 ! maintenance of protein location GO:0045185 91 40 1,000 1,79E-03 0,05667682 ! T cell differentiation GO:0030217 81 41 1,000 1,88E-03 0,05875115 ! epithelial cell differentiation GO:0030855 79 43 1,000 2,066E-03 0,06374177 ! B cell differentiation GO:0030183 107 44 1,000 2,163E-03 0,06586641 ! maintenance of location in cell GO:0051651 97 44 1,000 2,163E-03 0,06504308 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 2,261E-03 0,0671613 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 2,261E-03 0,06634226 ! pigmentation GO:0043473 100 46 1,000 2,361E-03 0,06845421 ! positive regulation of protein transport GO:0051222 72 46 1,000 2,361E-03 0,06763928 ! protein homooligomerization GO:0051260 76 47 1,000 2,464E-03 0,06974511 ! regulation of ion transport GO:0043269 77 49 1,000 2,675E-03 0,07484351 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 2,675E-03 0,07398324 GO:0019724|B cell mediated immunity, ! neuromuscular process GO:0050905 99 50 1,000 2,784E-03 0,07611458 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 2,784E-03 0,07525936 ! positive regulation of cytokine production GO:0001819 86 50 1,000 2,784E-03 0,07442315 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 2,895E-03 0,07653366 ! chromatin remodeling GO:0006338 109 51 1,000 2,895E-03 0,07570177 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 2,895E-03 0,07488778 ! response to UV GO:0009411 104 53 1,000 3,122E-03 0,07991783 ! RNA elongation GO:0006354 79 55 1,000 3,358E-03 0,08504797 ! maintenance of location GO:0051235 118 57 1,000 3,602E-03 0,0902738 ! adult behavior GO:0030534 99 58 1,000 3,727E-03 0,0924423 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 3,983E-03 0,09778135 ! regulation of homeostatic process GO:0032844 134 62 1,000 4,247E-03 0,10320591 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 4,518E-03 0,10871222 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 4,657E-03 0,11094293 ! actin filament organization GO:0007015 148 66 1,000 4,798E-03 0,1131761 ! extracellular matrix organization GO:0030198 133 66 1,000 4,798E-03 0,1120773 ! secondary metabolic process GO:0019748 116 66 1,000 4,798E-03 0,11099963 ! adaptive immune response GO:0002250 119 67 1,000 4,941E-03 0,11321318 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell cycle checkpoint GO:0000075 137 69 1,000 5,232E-03 0,11875713 ! humoral immune response GO:0006959 109 71 1,000 5,531E-03 0,12437136 ! B cell activation GO:0042113 160 71 1,000 5,531E-03 0,12321977 ! regulation of caspase activity GO:0043281 122 72 1,000 5,683E-03 0,12545336 ! leukocyte mediated immunity GO:0002443 128 74 1,000 5,994E-03 0,13110532 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 5,994E-03 0,12992419 ! lymphocyte differentiation GO:0030098 167 75 1,000 6,152E-03 0,13216111 ! defense response to bacterium GO:0042742 89 76 1,000 6,312E-03 0,13439882 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 6,638E-03 0,14009426 ! protein oligomerization GO:0051259 139 78 1,000 6,638E-03 0,13887605 ! regulation of peptidase activity GO:0052547 134 79 1,000 6,804E-03 0,14111529 ! protein import into nucleus GO:0006606 158 80 1,000 6,971E-03 0,14335475 ! T cell activation GO:0042110 168 81 1,000 7,141E-03 0,14559433 ! nuclear import GO:0051170 161 81 1,000 7,141E-03 0,14437084 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 7,779E-03 0,15597097 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,779E-03 0,15468196 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,779E-03 0,15341407 ! positive regulation of helicase activity GO:0051096 11 5 0,000 7,779E-03 0,1521668 ! neuron fate determination GO:0048664 7 5 0,000 7,779E-03 0,15093965 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,779E-03 0,14973213 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 7,779E-03 0,14854378 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,779E-03 0,14737415 ! polyol transport GO:0015791 12 5 0,000 7,779E-03 0,14622279 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 7,779E-03 0,14508928 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,779E-03 0,14397321 ! response to superoxide GO:0000303 10 5 0,000 7,779E-03 0,14287417 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,779E-03 0,14179179 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 7,779E-03 0,14072569 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 7,779E-03 0,1396755 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,779E-03 0,13864086 ! female meiosis GO:0007143 7 5 0,000 7,779E-03 0,13762145 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,779E-03 0,13661691 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,779E-03 0,13562693 ! cobalt ion transport GO:0006824 11 5 0,000 7,779E-03 0,1346512 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 7,779E-03 0,13368941 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 7,779E-03 0,13274125 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 7,779E-03 0,13180646 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,779E-03 0,13088473 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,779E-03 0,12997581 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 7,779E-03 0,12907943 ! embryonic camera-type eye development GO:0031076 10 5 0,000 7,779E-03 0,12819532 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,779E-03 0,12732324 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 7,779E-03 0,12646295 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 7,779E-03 0,12561421 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,779E-03 0,12477678 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,779E-03 0,12395044 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,779E-03 0,12313498 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 7,779E-03 0,12233017 ! negative chemotaxis GO:0050919 14 5 0,000 7,779E-03 0,12153582 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,779E-03 0,12075172 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,779E-03 0,11997767 ! sensory perception of bitter taste GO:0050913 7 5 0,000 7,779E-03 0,11921348 ! behavioral response to pain GO:0048266 9 5 0,000 7,779E-03 0,11845897 ! clathrin coat assembly GO:0048268 14 5 0,000 7,779E-03 0,11771394 ! Notch receptor processing GO:0007220 8 5 0,000 7,779E-03 0,11697823 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,779E-03 0,11625166 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,779E-03 0,11553405 ! micturition GO:0060073 9 5 0,000 7,779E-03 0,11482526 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,779E-03 0,1141251 ! copulation GO:0007620 9 5 0,000 7,779E-03 0,11343343 ! glial cell fate commitment GO:0021781 13 5 0,000 7,779E-03 0,1127501 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,779E-03 0,11207495 ! spermidine metabolic process GO:0008216 7 5 0,000 7,779E-03 0,11140784 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,779E-03 0,11074862 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,779E-03 0,11009716 ! apoptotic cell clearance GO:0043277 20 5 0,000 7,779E-03 0,10945331 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,779E-03 0,10881696 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,779E-03 0,10818796 ! grooming behavior GO:0007625 6 5 0,000 7,779E-03 0,10756619 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,779E-03 0,10695152 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 7,779E-03 0,10634384 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,779E-03 0,10574303 ! positive regulation of glycolysis GO:0045821 14 5 0,000 7,779E-03 0,10514897 ! lymph vessel development GO:0001945 10 5 0,000 7,779E-03 0,10456155 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 7,779E-03 0,10398065 ! endochondral ossification GO:0001958 16 5 0,000 7,779E-03 0,10340617 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,779E-03 0,102838 ! parathyroid gland development GO:0060017 13 5 0,000 7,779E-03 0,10227605 ! anagen GO:0042640 6 5 0,000 7,779E-03 0,1017202 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,779E-03 0,10117036 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,779E-03 0,10062643 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 7,779E-03 0,10008832 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 7,779E-03 0,09955594 ! dorsal spinal cord development GO:0021516 7 5 0,000 7,779E-03 0,09902919 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 7,779E-03 0,09850798 ! sphingoid catabolic process GO:0046521 6 5 0,000 7,779E-03 0,09799223 ! skeletal myofibril assembly GO:0014866 10 5 0,000 7,779E-03 0,09748186 ! smooth muscle tissue development GO:0048745 28 5 0,000 7,779E-03 0,09697677 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,779E-03 0,09647689 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,779E-03 0,09598214 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,779E-03 0,09549243 ! cardiac muscle fiber development GO:0048739 10 5 0,000 7,779E-03 0,0950077 ! transepithelial chloride transport GO:0030321 9 5 0,000 7,779E-03 0,09452786 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,779E-03 0,09405285 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 7,779E-03 0,09358258 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 7,779E-03 0,093117 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,779E-03 0,09265602 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,779E-03 0,09219959 ! histidine catabolic process GO:0006548 6 5 0,000 7,779E-03 0,09174763 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 7,779E-03 0,09130008 ! microvillus organization GO:0032528 7 5 0,000 7,779E-03 0,09085688 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 7,779E-03 0,09041796 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,779E-03 0,08998325 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,779E-03 0,08955271 ! tryptophan metabolic process GO:0006568 9 5 0,000 7,779E-03 0,08912627 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 7,779E-03 0,08870387 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,779E-03 0,08828546 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 7,779E-03 0,08787097 ! polyol catabolic process GO:0046174 7 5 0,000 7,779E-03 0,08746036 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,779E-03 0,08705357 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,779E-03 0,08665054 ! muscle cell migration GO:0014812 8 5 0,000 7,779E-03 0,08625123 ! mitochondrial fission GO:0000266 8 5 0,000 7,779E-03 0,08585558 ! sister chromatid cohesion GO:0007062 12 5 0,000 7,779E-03 0,08546355 ! mRNA transcription GO:0009299 9 5 0,000 7,779E-03 0,08507508 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 7,779E-03 0,08469012 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 7,779E-03 0,08430863 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 7,779E-03 0,08393057 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,779E-03 0,08355588 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,779E-03 0,08318452 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,779E-03 0,08281645 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,779E-03 0,08245162 ! response to food GO:0032094 6 5 0,000 7,779E-03 0,08208999 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,779E-03 0,08173151 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,779E-03 0,08137616 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 7,779E-03 0,08102388 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,779E-03 0,08067464 ! paraxial mesoderm development GO:0048339 14 5 0,000 7,779E-03 0,0803284 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 7,779E-03 0,07998511 ! forebrain neuron development GO:0021884 13 5 0,000 7,779E-03 0,07964475 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,779E-03 0,07930727 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 7,779E-03 0,07897264 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,779E-03 0,07864083 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,779E-03 0,07831179 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,779E-03 0,07798549 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 7,779E-03 0,0776619 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,779E-03 0,07734098 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 7,779E-03 0,0770227 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 7,779E-03 0,07670704 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,779E-03 0,07639395 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 7,779E-03 0,0760834 ! basic amino acid transport GO:0015802 11 5 0,000 7,779E-03 0,07577537 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,779E-03 0,07546983 ! early endosome to late endosome transport GO:0045022 12 5 0,000 7,779E-03 0,07516673 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,779E-03 0,07486607 ! depyrimidination GO:0045008 10 5 0,000 7,779E-03 0,0745678 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,779E-03 0,07427189 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,779E-03 0,07397833 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,779E-03 0,07368707 ! zinc ion homeostasis GO:0055069 8 5 0,000 7,779E-03 0,0733981 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 7,779E-03 0,07311139 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 7,779E-03 0,07282691 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,779E-03 0,07254464 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,779E-03 0,07226454 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,779E-03 0,0719866 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 7,779E-03 0,07171079 ! peptidyl-arginine modification GO:0018195 9 5 0,000 7,779E-03 0,07143709 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,779E-03 0,07116546 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,779E-03 0,0708959 ! response to arsenic GO:0046685 10 5 0,000 7,779E-03 0,07062836 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,779E-03 0,07036284 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,779E-03 0,07009931 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 7,779E-03 0,06983775 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 7,779E-03 0,06957813 ! response to cadmium ion GO:0046686 7 5 0,000 7,779E-03 0,06932043 ! bile acid biosynthetic process GO:0006699 6 5 0,000 7,779E-03 0,06906464 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 7,779E-03 0,06881072 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,779E-03 0,06855867 ! decidualization GO:0046697 11 5 0,000 7,779E-03 0,06830846 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 7,779E-03 0,06806006 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,779E-03 0,06781347 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,779E-03 0,06756865 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 7,779E-03 0,0673256 ! base conversion or substitution editing GO:0016553 5 5 0,000 7,779E-03 0,06708429 ! neural tube patterning GO:0021532 7 5 0,000 7,779E-03 0,0668447 ! embryonic cleavage GO:0040016 6 5 0,000 7,779E-03 0,06660682 ! peroxisome fission GO:0016559 5 5 0,000 7,779E-03 0,06637063 ! histone demethylation GO:0016577 10 5 0,000 7,779E-03 0,0661361 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 7,779E-03 0,06590323 ! mitotic recombination GO:0006312 9 5 0,000 7,779E-03 0,06567199 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,779E-03 0,06544237 ! metaphase plate congression GO:0051310 7 5 0,000 7,779E-03 0,06521434 ! regulation of sterol transport GO:0032371 7 5 0,000 7,779E-03 0,06498791 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,779E-03 0,06476303 ! enteric nervous system development GO:0048484 8 5 0,000 7,779E-03 0,06453971 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 7,779E-03 0,06431793 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 7,779E-03 0,06409766 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 7,779E-03 0,0638789 ! muscle cell proliferation GO:0033002 11 5 0,000 7,779E-03 0,06366162 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,779E-03 0,06344582 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 7,779E-03 0,06323148 ! plasminogen activation GO:0031639 5 5 0,000 7,779E-03 0,06301857 ! B cell homeostasis GO:0001782 13 5 0,000 7,779E-03 0,0628071 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,779E-03 0,06259705 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,779E-03 0,06238839 ! metaphase GO:0051323 8 5 0,000 7,779E-03 0,06218112 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 7,779E-03 0,06197522 ! cellular response to nutrient GO:0031670 8 5 0,000 7,779E-03 0,06177068 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,779E-03 0,06156749 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,779E-03 0,06136563 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,779E-03 0,06116509 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 7,779E-03 0,06096585 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 7,779E-03 0,06076791 ! response to redox state GO:0051775 5 5 0,000 7,779E-03 0,06057125 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 7,779E-03 0,06037586 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 7,779E-03 0,06018173 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,779E-03 0,05998884 ! regulation of telomerase activity GO:0051972 6 5 0,000 7,779E-03 0,05979718 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,779E-03 0,05960674 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 7,779E-03 0,05941751 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,779E-03 0,05922948 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 7,779E-03 0,05904264 ! striatum development GO:0021756 9 5 0,000 7,779E-03 0,05885697 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 7,779E-03 0,05867247 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 7,779E-03 0,05848911 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,779E-03 0,05830691 ! glial cell migration GO:0008347 11 5 0,000 7,779E-03 0,05812583 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,779E-03 0,05794587 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 7,779E-03 0,05776703 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,779E-03 0,05758928 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,779E-03 0,05741263 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,779E-03 0,05723705 ! neuroprotection GO:0043526 6 5 0,000 7,779E-03 0,05706255 ! neural plate development GO:0001840 8 5 0,000 7,779E-03 0,05688911 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,779E-03 0,05671672 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,779E-03 0,05654537 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,779E-03 0,05637505 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 7,779E-03 0,05620576 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 7,779E-03 0,05603748 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,779E-03 0,0558702 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,779E-03 0,05570392 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,779E-03 0,05553863 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,779E-03 0,05537431 ! spindle assembly GO:0051225 6 5 0,000 7,779E-03 0,05521096 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 7,779E-03 0,05504858 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,779E-03 0,05488715 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,779E-03 0,05472666 ! drug metabolic process GO:0017144 6 5 0,000 7,779E-03 0,0545671 ! stem cell division GO:0017145 11 5 0,000 7,779E-03 0,05440848 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,779E-03 0,05425077 ! organ regeneration GO:0031100 7 5 0,000 7,779E-03 0,05409398 ! carnitine metabolic process GO:0009437 7 5 0,000 7,779E-03 0,05393809 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 7,779E-03 0,05378309 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,779E-03 0,05362899 ! protein localization in nucleus GO:0034504 176 87 1,000 8,196E-03 0,05634112 ! regulation of DNA binding GO:0051101 155 88 1,000 8,378E-03 0,05743035 ! regulation of neurological system process GO:0031644 148 88 1,000 8,378E-03 0,0572672 ! ATP biosynthetic process GO:0006754 159 88 1,000 8,378E-03 0,05710497 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,328E-03 0,06339741 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,328E-03 0,06321883 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 9,328E-03 0,06304124 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,328E-03 0,06286466 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,328E-03 0,06268906 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 9,328E-03 0,06251444 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 9,328E-03 0,06234079 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,328E-03 0,0621681 ! sleep GO:0030431 13 6 0,000 9,328E-03 0,06199636 ! response to oxygen radical GO:0000305 11 6 0,000 9,328E-03 0,06182557 ! positive regulation of axon extension GO:0045773 11 6 0,000 9,328E-03 0,06165572 ! myoblast cell fate commitment GO:0048625 16 6 0,000 9,328E-03 0,0614868 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 9,328E-03 0,06131881 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 9,328E-03 0,06115173 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,328E-03 0,06098555 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,328E-03 0,06082028 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 9,328E-03 0,0606559 ! forebrain regionalization GO:0021871 8 6 0,000 9,328E-03 0,06049241 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,328E-03 0,06032979 ! male meiosis GO:0007140 7 6 0,000 9,328E-03 0,06016805 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,328E-03 0,06000717 ! response to zinc ion GO:0010043 9 6 0,000 9,328E-03 0,05984716 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,328E-03 0,05968799 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 9,328E-03 0,05952966 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 9,328E-03 0,05937218 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,328E-03 0,05921552 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,328E-03 0,05905969 ! malate metabolic process GO:0006108 11 6 0,000 9,328E-03 0,05890468 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 9,328E-03 0,05875048 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 9,328E-03 0,05859708 ! protein refolding GO:0042026 15 6 0,000 9,328E-03 0,05844449 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,328E-03 0,05829268 ! opsonization GO:0008228 8 6 0,000 9,328E-03 0,05814167 ! mating behavior GO:0007617 7 6 0,000 9,328E-03 0,05799143 ! neuron remodeling GO:0016322 15 6 0,000 9,328E-03 0,05784197 ! erythrocyte maturation GO:0043249 7 6 0,000 9,328E-03 0,05769327 ! embryonic hemopoiesis GO:0035162 14 6 0,000 9,328E-03 0,05754534 ! equilibrioception GO:0050957 14 6 0,000 9,328E-03 0,05739817 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,328E-03 0,05725174 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 9,328E-03 0,05710606 ! photoreceptor cell development GO:0042461 10 6 0,000 9,328E-03 0,05696112 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,328E-03 0,05681692 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,328E-03 0,05667344 ! response to interferon-gamma GO:0034341 15 6 0,000 9,328E-03 0,05653069 ! toxin metabolic process GO:0009404 11 6 0,000 9,328E-03 0,05638865 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,328E-03 0,05624733 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,328E-03 0,05610671 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 9,328E-03 0,05596679 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 9,328E-03 0,05582757 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 9,328E-03 0,05568904 ! cGMP-mediated signaling GO:0019934 13 6 0,000 9,328E-03 0,0555512 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,328E-03 0,05541403 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 9,328E-03 0,05527754 ! thymic T cell selection GO:0045061 12 6 0,000 9,328E-03 0,05514173 ! protein lipoylation GO:0009249 10 6 0,000 9,328E-03 0,05500658 ! cysteine metabolic process GO:0006534 10 6 0,000 9,328E-03 0,05487209 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,328E-03 0,05473825 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,328E-03 0,05460507 ! glutamate catabolic process GO:0006538 10 6 0,000 9,328E-03 0,05447253 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 9,328E-03 0,05434064 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 9,328E-03 0,05420938 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 9,328E-03 0,05407875 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 9,328E-03 0,05394876 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,328E-03 0,05381938 ! hyperosmotic response GO:0006972 9 6 0,000 9,328E-03 0,05369063 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 9,328E-03 0,05356249 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,328E-03 0,05343496 ! urea metabolic process GO:0019627 7 6 0,000 9,328E-03 0,05330804 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,328E-03 0,05318171 ! neutrophil activation GO:0042119 8 6 0,000 9,328E-03 0,05305599 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,328E-03 0,05293086 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 9,328E-03 0,05280631 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,328E-03 0,05268235 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,328E-03 0,05255898 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,328E-03 0,05243618 ! neuron apoptosis GO:0051402 9 6 0,000 9,328E-03 0,05231395 ! nucleoside salvage GO:0043174 9 6 0,000 9,328E-03 0,05219229 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 9,328E-03 0,05207119 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,328E-03 0,05195066 ! T cell mediated immunity GO:0002456 16 6 0,000 9,328E-03 0,05183068 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,328E-03 0,05171125 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 9,328E-03 0,05159238 ! carnitine transport GO:0015879 10 6 0,000 9,328E-03 0,05147404 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 9,328E-03 0,05135625 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,328E-03 0,051239 ! positive regulation of exocytosis GO:0045921 8 6 0,000 9,328E-03 0,05112229 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 9,328E-03 0,0510061 ! 5S class rRNA transcription GO:0042791 11 6 0,000 9,328E-03 0,05089044 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,328E-03 0,0507753 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 9,328E-03 0,05066068 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 9,328E-03 0,05054658 ! sodium ion homeostasis GO:0055078 11 6 0,000 9,328E-03 0,050433 ! establishment of spindle localization GO:0051293 12 6 0,000 9,328E-03 0,05031992 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,328E-03 0,05020734 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,328E-03 0,05009527 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 9,328E-03 0,0499837 ! neural nucleus development GO:0048857 14 6 0,000 9,328E-03 0,04987263 ! astrocyte development GO:0014002 15 6 0,000 9,328E-03 0,04976205 ! protein targeting to lysosome GO:0006622 10 6 0,000 9,328E-03 0,04965195 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,328E-03 0,04954235 ! interaction with symbiont GO:0051702 13 6 0,000 9,328E-03 0,04943322 ! regulation of dendrite development GO:0050773 16 6 0,000 9,328E-03 0,04932458 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,328E-03 0,04921641 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 9,328E-03 0,04910872 ! response to copper ion GO:0046688 10 6 0,000 9,328E-03 0,04900149 ! response to exogenous dsRNA GO:0043330 10 6 0,000 9,328E-03 0,04889473 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 9,328E-03 0,04878844 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,328E-03 0,04868261 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,328E-03 0,04857724 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,328E-03 0,04847232 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 9,328E-03 0,04836785 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,328E-03 0,04826383 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,328E-03 0,04816026 ! hair follicle maturation GO:0048820 7 6 0,000 9,328E-03 0,04805714 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,328E-03 0,04795445 ! Schwann cell development GO:0014044 15 6 0,000 9,328E-03 0,0478522 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,328E-03 0,04775039 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,328E-03 0,04764901 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 9,328E-03 0,04754806 ! subpallium development GO:0021544 10 6 0,000 9,328E-03 0,04744753 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 9,328E-03 0,04734743 ! histone ubiquitination GO:0016574 8 6 0,000 9,328E-03 0,04724775 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 9,328E-03 0,04714849 ! maintenance of organ identity GO:0048496 9 6 0,000 9,328E-03 0,04704965 ! G2 phase GO:0051319 16 6 0,000 9,328E-03 0,04695122 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 9,328E-03 0,0468532 ! establishment of planar polarity GO:0001736 7 6 0,000 9,328E-03 0,04675559 ! regulation of mast cell activation GO:0033003 12 6 0,000 9,328E-03 0,04665838 ! membrane to membrane docking GO:0022614 14 6 0,000 9,328E-03 0,04656158 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,328E-03 0,04646518 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 9,328E-03 0,04636918 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,328E-03 0,04627357 ! receptor internalization GO:0031623 10 6 0,000 9,328E-03 0,04617836 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 9,328E-03 0,04608354 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 9,328E-03 0,0459891 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,328E-03 0,04589506 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 9,328E-03 0,04580139 ! protein deubiquitination GO:0016579 14 6 0,000 9,328E-03 0,04570811 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 9,328E-03 0,04561521 ! protein destabilization GO:0031648 9 6 0,000 9,328E-03 0,04552268 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,328E-03 0,04543053 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 9,328E-03 0,04533875 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,328E-03 0,04524735 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 9,328E-03 0,0451563 ! progesterone metabolic process GO:0042448 10 6 0,000 9,328E-03 0,04506563 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 9,328E-03 0,04497532 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 9,328E-03 0,04488537 ! negative regulation of axon extension GO:0030517 21 6 0,000 9,328E-03 0,04479577 ! removal of superoxide radicals GO:0019430 11 6 0,000 9,328E-03 0,04470654 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,328E-03 0,04461766 ! determination of adult lifespan GO:0008340 15 6 0,000 9,328E-03 0,04452913 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 9,328E-03 0,04444096 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 9,328E-03 0,04435313 ! cerebellar cortex formation GO:0021697 8 6 0,000 9,328E-03 0,04426565 ! catecholamine transport GO:0051937 9 6 0,000 9,328E-03 0,04417851 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 9,328E-03 0,04409172 ! sensory cilium assembly GO:0035058 10 6 0,000 9,328E-03 0,04400526 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,328E-03 0,04391915 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 9,328E-03 0,04383337 ! maternal placenta development GO:0001893 12 6 0,000 9,328E-03 0,04374792 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 9,328E-03 0,04366281 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,328E-03 0,04357803 ! negative regulation of B cell activation GO:0050869 13 6 0,000 9,328E-03 0,04349357 ! protein amino acid prenylation GO:0018346 16 6 0,000 9,328E-03 0,04340945 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,328E-03 0,04332564 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 9,328E-03 0,04324216 ! positive regulation of coagulation GO:0050820 12 6 0,000 9,328E-03 0,04315901 ! transcription initiation GO:0006352 153 94 1,000 9,51E-03 0,04391834 ! leukocyte differentiation GO:0002521 202 96 1,000 9,902E-03 0,04563937 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 9,902E-03 0,04555211 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 1,000 9,902E-03 0,04546517 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,01010029 0,0462882 ! response to virus GO:0009615 160 98 1,000 0,01030054 0,04711617 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,01030054 0,04702677 ! tRNA transcription GO:0009304 14 7 0,000 0,01087413 0,04955143 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01087413 0,04945776 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01087413 0,04936445 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01087413 0,04927148 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01087413 0,04917887 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01087413 0,0490866 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01087413 0,04899468 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01087413 0,0489031 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01087413 0,04881186 ! prostate gland development GO:0030850 13 7 0,000 0,01087413 0,04872096 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01087413 0,0486304 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01087413 0,04854018 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01087413 0,04845029 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01087413 0,04836073 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01087413 0,04827151 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01087413 0,04818261 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01087413 0,04809404 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01087413 0,04800579 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01087413 0,04791787 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01087413 0,04783027 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01087413 0,04774299 ! glycolipid transport GO:0046836 10 7 0,000 0,01087413 0,04765602 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01087413 0,04756938 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01087413 0,04748304 ! neuron adhesion GO:0007158 12 7 0,000 0,01087413 0,04739702 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01087413 0,04731131 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01087413 0,04722592 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01087413 0,04714082 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01087413 0,04705604 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01087413 0,04697156 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01087413 0,04688738 ! mRNA stabilization GO:0048255 18 7 0,000 0,01087413 0,0468035 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01087413 0,04671992 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01087413 0,04663664 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01087413 0,04655366 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01087413 0,04647097 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01087413 0,04638858 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01087413 0,04630647 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01087413 0,04622466 ! lipoprotein transport GO:0042953 14 7 0,000 0,01087413 0,04614313 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01087413 0,0460619 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01087413 0,04598094 ! rhythmic behavior GO:0007622 15 7 0,000 0,01087413 0,04590028 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01087413 0,04581989 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01087413 0,04573979 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01087413 0,04565996 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01087413 0,04558041 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01087413 0,04550114 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01087413 0,04542215 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01087413 0,04534343 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01087413 0,04526498 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01087413 0,0451868 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01087413 0,04510889 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01087413 0,04503125 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01087413 0,04495388 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01087413 0,04487677 ! spinal cord patterning GO:0021511 13 7 0,000 0,01087413 0,04479993 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01087413 0,04472335 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01087413 0,04464703 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01087413 0,04457097 ! adrenal gland development GO:0030325 17 7 0,000 0,01087413 0,04449517 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01087413 0,04441962 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01087413 0,04434433 ! ovulation GO:0030728 9 7 0,000 0,01087413 0,0442693 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01087413 0,04419452 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01087413 0,04412 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01087413 0,04404572 ! microtubule nucleation GO:0007020 20 7 0,000 0,01087413 0,04397169 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01087413 0,04389791 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01087413 0,04382438 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01087413 0,0437511 GO:0021940|positive regulation of granule cell precursor proliferation, ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01087413 0,04367806 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01087413 0,04360526 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01087413 0,04353271 ! galactose metabolic process GO:0006012 13 7 0,000 0,01087413 0,04346039 ! vesicle fusion GO:0006906 17 7 0,000 0,01087413 0,04338832 ! response to dietary excess GO:0002021 8 7 0,000 0,01087413 0,04331649 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01087413 0,04324489 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01087413 0,04317353 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01087413 0,0431024 ! organ growth GO:0035265 15 7 0,000 0,01087413 0,04303151 ! purine salvage GO:0043101 10 7 0,000 0,01087413 0,04296085 ! nucleoside transport GO:0015858 8 7 0,000 0,01087413 0,04289042 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01087413 0,04282022 ! parturition GO:0007567 14 7 0,000 0,01087413 0,04275026 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01087413 0,04268052 ! rRNA modification GO:0000154 14 7 0,000 0,01087413 0,04261101 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01087413 0,04254172 ! spindle checkpoint GO:0031577 15 7 0,000 0,01087413 0,04247266 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01087413 0,04240382 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01087413 0,04233521 ! macrophage differentiation GO:0030225 11 7 0,000 0,01087413 0,04226681 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01087413 0,04219864 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01087413 0,04213069 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01087413 0,04206295 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01087413 0,04199544 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01087413 0,04192814 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01087413 0,04186105 ! fibrinolysis GO:0042730 10 7 0,000 0,01087413 0,04179418 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01087413 0,04172752 ! eating behavior GO:0042755 7 7 0,000 0,01087413 0,04166108 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01087413 0,04159484 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01087413 0,04152882 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01087413 0,04146301 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01087413 0,0413974 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01087413 0,041332 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01087413 0,04126681 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01087413 0,04120182 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01087413 0,04113704 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01087413 0,04107246 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01087413 0,04100808 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01087413 0,04094391 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01087413 0,04087993 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01087413 0,04081616 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01087413 0,04075258 ! regulation of meiosis GO:0040020 12 7 0,000 0,01087413 0,0406892 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01087413 0,04062602 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01087413 0,04056303 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01087413 0,04050024 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01087413 0,04043765 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01087413 0,04037524 ! transcription termination GO:0006353 13 7 0,000 0,01087413 0,04031303 ! response to tumor cell GO:0002347 13 7 0,000 0,01087413 0,04025101 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01087413 0,04018918 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01087413 0,04012754 ! anaphase GO:0051322 17 7 0,000 0,01087413 0,04006609 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01087413 0,04000483 ! axonal fasciculation GO:0007413 18 7 0,000 0,01087413 0,03994375 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01087413 0,03988286 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01087413 0,03982216 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01087413 0,03976164 ! diuresis GO:0030146 12 7 0,000 0,01087413 0,0397013 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01087413 0,03964115 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01087413 0,03958118 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01087413 0,03952139 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01087413 0,03946178 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01087413 0,03940235 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01087413 0,03934309 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01087413 0,03928402 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01087413 0,03922512 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01087413 0,0391664 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01087413 0,03910786 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01087413 0,03904949 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01087413 0,03899129 ! lymph node development GO:0048535 10 7 0,000 0,01087413 0,03893327 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01087413 0,03887542 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01087413 0,03881774 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01087413 0,03876023 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01087413 0,0387029 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01087413 0,03864573 ! adult feeding behavior GO:0008343 9 7 0,000 0,01087413 0,03858873 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01087413 0,0385319 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01087413 0,03847523 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01087413 0,03841873 ! muscle adaptation GO:0043500 14 7 0,000 0,01087413 0,0383624 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01087413 0,03830623 ! retina homeostasis GO:0001895 12 7 0,000 0,01087413 0,03825023 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01087413 0,03819439 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01087413 0,03813871 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01087413 0,0380832 ! protein prenylation GO:0018342 18 7 0,000 0,01087413 0,03802784 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01087413 0,03797265 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01087413 0,03791762 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01087413 0,03786275 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0124181 0,04317622 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0124181 0,04311392 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,0124181 0,0430518 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0124181 0,04298985 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0124181 0,04292809 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0124181 0,0428665 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0124181 0,04280508 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0124181 0,04274384 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0124181 0,04268278 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0124181 0,04262189 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0124181 0,04256118 ! meiotic prophase I GO:0007128 13 8 0,000 0,0124181 0,04250064 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0124181 0,04244027 ! oligopeptide transport GO:0006857 15 8 0,000 0,0124181 0,04238007 ! UTP metabolic process GO:0046051 8 8 0,000 0,0124181 0,04232004 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0124181 0,04226018 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0124181 0,04220049 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0124181 0,04214097 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0124181 0,04208162 ! succinate metabolic process GO:0006105 14 8 0,000 0,0124181 0,04202243 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0124181 0,04196341 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0124181 0,04190455 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0124181 0,04184586 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0124181 0,04178734 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0124181 0,04172898 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0124181 0,04167078 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0124181 0,04161274 ! reflex GO:0060004 16 8 0,000 0,0124181 0,04155486 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0124181 0,04149715 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0124181 0,04143959 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0124181 0,0413822 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0124181 0,04132496 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0124181 0,04126788 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0124181 0,04121096 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0124181 0,0411542 ! pigment granule organization GO:0048753 16 8 0,000 0,0124181 0,04109759 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0124181 0,04104114 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0124181 0,04098484 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0124181 0,04092869 ! histidine metabolic process GO:0006547 16 8 0,000 0,0124181 0,0408727 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0124181 0,04081687 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0124181 0,04076118 ! glycine catabolic process GO:0006546 13 8 0,000 0,0124181 0,04070565 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0124181 0,04065027 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0124181 0,04059504 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,0124181 0,04053996 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0124181 0,04048502 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0124181 0,04043024 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0124181 0,0403756 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0124181 0,04032112 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0124181 0,04026678 ! macrophage activation GO:0042116 12 8 0,000 0,0124181 0,04021258 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0124181 0,04015853 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0124181 0,04010463 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0124181 0,04005087 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0124181 0,03999725 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0124181 0,03994378 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0124181 0,03989045 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0124181 0,03983726 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0124181 0,03978422 ! osteoblast development GO:0002076 16 8 0,000 0,0124181 0,03973131 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0124181 0,03967855 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0124181 0,03962592 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0124181 0,03957344 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0124181 0,03952109 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0124181 0,03946889 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0124181 0,03941682 ! response to UV-B GO:0010224 16 8 0,000 0,0124181 0,03936488 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0124181 0,03931309 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0124181 0,03926143 ! intermediate filament organization GO:0045109 12 8 0,000 0,0124181 0,0392099 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0124181 0,03915852 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0124181 0,03910726 ! cellular extravasation GO:0045123 12 8 0,000 0,0124181 0,03905614 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0124181 0,03900515 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0124181 0,0389543 ! response to antibiotic GO:0046677 11 8 0,000 0,0124181 0,03890358 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0124181 0,03885299 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0124181 0,03880253 ! DNA topological change GO:0006265 12 8 0,000 0,0124181 0,0387522 ! response to tropane GO:0014073 15 8 0,000 0,0124181 0,038702 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0124181 0,03865194 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0124181 0,038602 ! melanosome transport GO:0032402 13 8 0,000 0,0124181 0,03855219 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,0124181 0,03850251 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0124181 0,03845296 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0124181 0,03840353 ! mast cell activation GO:0045576 14 8 0,000 0,0124181 0,03835423 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0124181 0,03830506 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0124181 0,03825601 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0124181 0,03820709 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0124181 0,0381583 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0124181 0,03810963 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0124181 0,03806108 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0124181 0,03801266 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0124181 0,03796435 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0124181 0,03791618 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0124181 0,03786812 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0124181 0,03782019 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0124181 0,03777237 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0124181 0,03772468 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0124181 0,03767711 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0124181 0,03762966 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0124181 0,03758232 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0124181 0,03753511 ! hormone catabolic process GO:0042447 17 8 0,000 0,0124181 0,03748801 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0124181 0,03744104 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0124181 0,03739418 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0124181 0,03734743 ! ATP catabolic process GO:0006200 11 8 0,000 0,0124181 0,03730081 ! blastocyst growth GO:0001832 19 8 0,000 0,0124181 0,0372543 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0124181 0,0372079 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0124181 0,03716163 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0124181 0,03711546 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0124181 0,03706941 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0124181 0,03702348 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0124181 0,03697766 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0124181 0,03693195 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0124181 0,03688635 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0124181 0,03684087 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0124181 0,0367955 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0124181 0,03675024 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0124181 0,0367051 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0124181 0,03666006 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0124181 0,03661513 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0124181 0,03657031 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0124181 0,03652561 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0124181 0,03648101 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01395971 0,04095983 ! axon extension GO:0048675 15 9 0,000 0,01395971 0,04090994 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01395971 0,04086017 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01395971 0,04081053 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01395971 0,040761 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01395971 0,04071159 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01395971 0,0406623 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01395971 0,04061313 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01395971 0,04056408 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01395971 0,04051515 ! phosphate transport GO:0006817 19 9 0,000 0,01395971 0,04046634 ! reproductive behavior GO:0019098 19 9 0,000 0,01395971 0,04041764 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01395971 0,04036907 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01395971 0,0403206 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01395971 0,04027226 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01395971 0,04022403 ! GTP metabolic process GO:0046039 9 9 0,000 0,01395971 0,04017591 ! RNA methylation GO:0001510 15 9 0,000 0,01395971 0,04012791 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01395971 0,04008003 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01395971 0,04003226 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01395971 0,0399846 ! artery development GO:0060840 24 9 0,000 0,01395971 0,03993705 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01395971 0,03988962 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01395971 0,0398423 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01395971 0,0397951 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01395971 0,039748 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01395971 0,03970102 ! chemosensory behavior GO:0007635 20 9 0,000 0,01395971 0,03965415 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01395971 0,03960738 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01395971 0,03956073 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01395971 0,03951419 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01395971 0,03946776 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01395971 0,03942143 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01395971 0,03937522 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01395971 0,03932911 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01395971 0,03928311 ! protein targeting to ER GO:0045047 22 9 0,000 0,01395971 0,03923722 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01395971 0,03919144 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01395971 0,03914576 ! T cell selection GO:0045058 23 9 0,000 0,01395971 0,03910019 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01395971 0,03905472 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01395971 0,03900936 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01395971 0,03896411 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01395971 0,03891896 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01395971 0,03887391 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01395971 0,03882897 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01395971 0,03878414 ! mannose metabolic process GO:0006013 13 9 0,000 0,01395971 0,0387394 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01395971 0,03869477 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01395971 0,03865024 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01395971 0,03860582 ! receptor clustering GO:0043113 18 9 0,000 0,01395971 0,03856149 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01395971 0,03851727 ! ruffle organization GO:0031529 15 9 0,000 0,01395971 0,03847315 ! retinol metabolic process GO:0042572 18 9 0,000 0,01395971 0,03842913 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01395971 0,03838521 ! behavioral fear response GO:0001662 22 9 0,000 0,01395971 0,0383414 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01395971 0,03829768 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01395971 0,03825406 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01395971 0,03821054 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01395971 0,03816712 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01395971 0,03812379 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01395971 0,03808057 ! segment specification GO:0007379 13 9 0,000 0,01395971 0,03803744 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01395971 0,03799441 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01395971 0,03795148 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01395971 0,03790865 ! response to amine stimulus GO:0014075 13 9 0,000 0,01395971 0,03786591 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01395971 0,03782327 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01395971 0,03778072 ! erythrocyte development GO:0048821 15 9 0,000 0,01395971 0,03773827 ! gas homeostasis GO:0033483 16 9 0,000 0,01395971 0,03769592 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01395971 0,03765366 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01395971 0,03761149 ! renal water homeostasis GO:0003091 14 9 0,000 0,01395971 0,03756942 ! postreplication repair GO:0006301 22 9 0,000 0,01395971 0,03752744 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01395971 0,03748556 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01395971 0,03744377 ! icosanoid secretion GO:0032309 15 9 0,000 0,01395971 0,03740207 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01395971 0,03736047 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01395971 0,03731896 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01395971 0,03727754 ! regulation of cell division GO:0051302 15 9 0,000 0,01395971 0,03723621 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01395971 0,03719497 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01395971 0,03715383 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01395971 0,03711278 ! sterol catabolic process GO:0016127 11 9 0,000 0,01395971 0,03707181 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01395971 0,03703094 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01395971 0,03699016 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01395971 0,03694946 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01395971 0,03690886 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01395971 0,03686834 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01395971 0,03682792 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01395971 0,03678758 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01395971 0,03674733 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01395971 0,03670717 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01395971 0,0366671 ! purine base metabolic process GO:0006144 21 9 0,000 0,01395971 0,03662711 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01395971 0,03658721 ! pigment granule transport GO:0051904 17 9 0,000 0,01395971 0,0365474 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01395971 0,03650768 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01395971 0,03646804 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01395971 0,03642848 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01395971 0,03638902 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01395971 0,03634963 ! mitochondrion localization GO:0051646 15 9 0,000 0,01395971 0,03631034 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01549897 0,04027053 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01549897 0,04022709 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01549897 0,04018374 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01549897 0,04014048 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01549897 0,04009732 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01549897 0,04005425 ! synapsis GO:0007129 13 10 0,000 0,01549897 0,04001128 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01549897 0,03996839 ! N-glycan processing GO:0006491 20 10 0,000 0,01549897 0,0399256 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01549897 0,0398829 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01549897 0,03984029 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01549897 0,03979777 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01549897 0,03975534 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01549897 0,039713 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01549897 0,03967076 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01549897 0,0396286 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01549897 0,03958653 ! androgen metabolic process GO:0008209 17 10 0,000 0,01549897 0,03954455 ! phospholipid efflux GO:0033700 16 10 0,000 0,01549897 0,03950266 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01549897 0,03946086 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01549897 0,03941914 ! lung alveolus development GO:0048286 26 10 0,000 0,01549897 0,03937752 ! pathogenesis GO:0009405 13 10 0,000 0,01549897 0,03933598 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01549897 0,03929453 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01549897 0,03925317 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01549897 0,03921189 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01549897 0,0391707 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01549897 0,0391296 ! endoderm development GO:0007492 16 10 0,000 0,01549897 0,03908858 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01549897 0,03904765 ! arginine catabolic process GO:0006527 13 10 0,000 0,01549897 0,03900681 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01549897 0,03896605 ! proline metabolic process GO:0006560 13 10 0,000 0,01549897 0,03892538 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01549897 0,03888479 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01549897 0,03884428 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01549897 0,03880386 ! V(D)J recombination GO:0033151 28 10 0,000 0,01549897 0,03876352 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01549897 0,03872327 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01549897 0,0386831 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01549897 0,03864302 ! B cell proliferation GO:0042100 18 10 0,000 0,01549897 0,03860301 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01549897 0,03856309 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01549897 0,03852325 ! multicellular organism growth GO:0035264 18 10 0,000 0,01549897 0,0384835 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01549897 0,03844382 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01549897 0,03840423 ! epithelial cell development GO:0002064 20 10 0,000 0,01549897 0,03836472 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01549897 0,03832529 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01549897 0,03828594 ! macroautophagy GO:0016236 17 10 0,000 0,01549897 0,03824668 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01549897 0,03820749 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01549897 0,03816838 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01549897 0,03812936 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01549897 0,03809041 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01549897 0,03805154 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01549897 0,03801275 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01549897 0,03797404 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01549897 0,03793541 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01549897 0,03789686 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01549897 0,03785839 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01549897 0,03781999 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01549897 0,03778167 ! response to dsRNA GO:0043331 20 10 0,000 0,01549897 0,03774343 ! DNA ligation GO:0006266 19 10 0,000 0,01549897 0,03770527 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01549897 0,03766718 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01549897 0,03762917 ! melanosome localization GO:0032400 16 10 0,000 0,01549897 0,03759124 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01549897 0,03755338 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01549897 0,0375156 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01549897 0,0374779 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01549897 0,03744027 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01549897 0,03740272 ! mRNA cleavage GO:0006379 17 10 0,000 0,01549897 0,03736524 ! protein sumoylation GO:0016925 15 10 0,000 0,01549897 0,03732784 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01549897 0,03729051 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01549897 0,03725326 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01549897 0,03721608 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01549897 0,03717897 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01549897 0,03714194 ! salivary gland development GO:0007431 27 10 0,000 0,01549897 0,03710499 ! prophase GO:0051324 15 10 0,000 0,01549897 0,0370681 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01549897 0,03703129 ! apical protein localization GO:0045176 15 10 0,000 0,01549897 0,03699455 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01549897 0,03695789 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01549897 0,0369213 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01549897 0,03688478 ! midbrain development GO:0030901 13 10 0,000 0,01549897 0,03684833 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01549897 0,03681195 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01549897 0,03677565 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01549897 0,03673942 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01549897 0,03670326 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01549897 0,03666717 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01549897 0,03663115 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01549897 0,0365952 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01549897 0,03655932 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01549897 0,03652352 ! oocyte development GO:0048599 17 10 0,000 0,01549897 0,03648778 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01549897 0,03645211 ! blastocyst formation GO:0001825 17 10 0,000 0,01549897 0,03641651 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01549897 0,03638099 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01549897 0,03634553 ! activation of innate immune response GO:0002218 12 10 0,000 0,01549897 0,03631014 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01549897 0,03627482 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01549897 0,03623956 ! response to nicotine GO:0035094 20 10 0,000 0,01549897 0,03620438 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01549897 0,03616926 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01549897 0,03613422 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01549897 0,03609924 ! localization within membrane GO:0051668 20 10 0,000 0,01549897 0,03606432 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01703587 0,03960222 ! respiratory burst GO:0045730 17 11 0,000 0,01703587 0,039564 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01703587 0,03952584 ! neuron fate specification GO:0048665 17 11 0,000 0,01703587 0,03948776 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01703587 0,03944976 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01703587 0,03941183 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,01703587 0,03937397 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01703587 0,03933618 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01703587 0,03929847 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01703587 0,03926082 ! response to pain GO:0048265 24 11 0,000 0,01703587 0,03922325 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01703587 0,03918575 ! T cell proliferation GO:0042098 26 11 0,000 0,01703587 0,03914833 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01703587 0,03911097 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01703587 0,03907369 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01703587 0,03903648 ! bone resorption GO:0045453 16 11 0,000 0,01703587 0,03899933 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01703587 0,03896226 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01703587 0,03892526 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01703587 0,03888833 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01703587 0,03885147 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01703587 0,03881468 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01703587 0,03877796 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01703587 0,0387413 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01703587 0,03870472 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01703587 0,03866821 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01703587 0,03863176 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01703587 0,03859539 ! lipid digestion GO:0044241 18 11 0,000 0,01703587 0,03855908 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01703587 0,03852284 ! UV protection GO:0009650 19 11 0,000 0,01703587 0,03848667 ! adult heart development GO:0007512 14 11 0,000 0,01703587 0,03845056 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01703587 0,03841453 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01703587 0,03837856 ! temperature homeostasis GO:0001659 17 11 0,000 0,01703587 0,03834266 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01703587 0,03830682 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01703587 0,03827105 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01703587 0,03823535 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01703587 0,03819972 ! regulation of organ growth GO:0046620 13 11 0,000 0,01703587 0,03816415 ! pigment granule localization GO:0051875 20 11 0,000 0,01703587 0,03812865 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01703587 0,03809322 ! vasoconstriction GO:0042310 18 11 0,000 0,01703587 0,03805785 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01703587 0,03802254 ! embryonic axis specification GO:0000578 18 11 0,000 0,01703587 0,0379873 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01703587 0,03795213 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01703587 0,03791702 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01703587 0,03788198 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01703587 0,037847 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01703587 0,03781208 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01703587 0,03777723 ! zymogen activation GO:0031638 15 11 0,000 0,01703587 0,03774245 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01703587 0,03770773 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01703587 0,03767307 ! nucleosome positioning GO:0016584 15 11 0,000 0,01703587 0,03763848 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01703587 0,03760394 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01703587 0,03756948 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01703587 0,03753507 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01703587 0,03750073 ! acid secretion GO:0046717 18 11 0,000 0,01703587 0,03746645 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01703587 0,03743224 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01703587 0,03739808 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01703587 0,03736399 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01703587 0,03732996 ! oocyte differentiation GO:0009994 18 11 0,000 0,01703587 0,037296 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01703587 0,03726209 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01703587 0,03722825 ! cholesterol efflux GO:0033344 19 11 0,000 0,01703587 0,03719446 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01703587 0,03716074 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01703587 0,03712708 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01703587 0,03709348 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01703587 0,03705995 ! embryonic gut development GO:0048566 15 11 0,000 0,01703587 0,03702647 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01703587 0,03699305 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01703587 0,03695969 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01703587 0,0369264 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01703587 0,03689316 ! defense response to fungus GO:0050832 13 11 0,000 0,01703587 0,03685998 ! developmental induction GO:0031128 19 11 0,000 0,01703587 0,03682686 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01703587 0,03679381 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01703587 0,03676081 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01703587 0,03672787 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01703587 0,03669499 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01703587 0,03666216 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01703587 0,0366294 ! nucleus localization GO:0051647 19 11 0,000 0,01703587 0,0365967 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01703587 0,03656405 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01857042 0,03982214 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01857042 0,03978668 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01857042 0,03975128 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01857042 0,03971595 ! virus-host interaction GO:0019048 29 12 0,000 0,01857042 0,03968067 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01857042 0,03964546 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01857042 0,03961032 ! cartilage condensation GO:0001502 20 12 0,000 0,01857042 0,03957523 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01857042 0,03954021 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01857042 0,03950525 ! protein complex disassembly GO:0043241 27 12 0,000 0,01857042 0,03947035 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01857042 0,03943552 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01857042 0,03940074 ! hippocampus development GO:0021766 26 12 0,000 0,01857042 0,03936603 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01857042 0,03933137 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01857042 0,03929678 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01857042 0,03926225 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01857042 0,03922778 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01857042 0,03919337 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01857042 0,03915902 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01857042 0,03912473 ! drug transport GO:0015893 16 12 0,000 0,01857042 0,0390905 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01857042 0,03905633 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01857042 0,03902222 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01857042 0,03898817 ! focal adhesion formation GO:0048041 35 12 0,000 0,01857042 0,03895418 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01857042 0,03892024 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01857042 0,03888637 ! forebrain cell migration GO:0021885 21 12 0,000 0,01857042 0,03885256 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01857042 0,0388188 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01857042 0,0387851 GO:0006509|membrane protein ectodomain proteolysis, ! entry into host cell GO:0030260 32 12 0,000 0,01857042 0,03875146 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01857042 0,03871788 ! monoamine transport GO:0015844 18 12 0,000 0,01857042 0,03868436 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01857042 0,0386509 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01857042 0,03861749 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01857042 0,03858414 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01857042 0,03855085 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01857042 0,03851762 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01857042 0,03848444 ! protein homotetramerization GO:0051289 21 12 0,000 0,01857042 0,03845132 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01857042 0,03841826 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01857042 0,03838526 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01857042 0,03835231 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01857042 0,03831942 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01857042 0,03828658 ! cranial nerve development GO:0021545 20 12 0,000 0,01857042 0,0382538 ! fucose catabolic process GO:0019317 22 12 0,000 0,01857042 0,03822108 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01857042 0,03818841 ! histone acetylation GO:0016573 26 12 0,000 0,01857042 0,0381558 ! histone methylation GO:0016571 26 12 0,000 0,01857042 0,03812324 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01857042 0,03809074 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01857042 0,0380583 ! gland morphogenesis GO:0022612 29 12 0,000 0,01857042 0,03802591 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01857042 0,03799357 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01857042 0,03796129 ! T cell homeostasis GO:0043029 25 12 0,000 0,01857042 0,03792907 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01857042 0,03789689 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01857042 0,03786478 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01857042 0,03783272 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01857042 0,03780071 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01857042 0,03776876 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01857042 0,03773686 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01857042 0,03770501 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01857042 0,03767322 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01857042 0,03764148 ! response to cold GO:0009409 17 12 0,000 0,01857042 0,0376098 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01857042 0,03757817 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01857042 0,03754659 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02010263 0,04061036 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02010263 0,04057629 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02010263 0,04054228 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02010263 0,04050832 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02010263 0,04047442 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02010263 0,04044058 ! lipid localization GO:0010876 28 13 0,000 0,02010263 0,0404068 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02010263 0,04037307 ! organelle fusion GO:0048284 32 13 0,000 0,02010263 0,0403394 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02010263 0,04030578 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02010263 0,04027222 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02010263 0,04023872 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02010263 0,04020527 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02010263 0,04017187 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02010263 0,04013854 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02010263 0,04010525 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02010263 0,04007203 ! methionine metabolic process GO:0006555 27 13 0,000 0,02010263 0,04003885 ! plasma membrane organization GO:0007009 24 13 0,000 0,02010263 0,04000574 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02010263 0,03997267 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02010263 0,03993967 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02010263 0,03990671 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02010263 0,03987381 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02010263 0,03984097 ! response to X-ray GO:0010165 25 13 0,000 0,02010263 0,03980818 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02010263 0,03977544 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02010263 0,03974276 ! exocrine system development GO:0035272 32 13 0,000 0,02010263 0,03971013 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02010263 0,03967755 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02010263 0,03964503 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02010263 0,03961256 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02010263 0,03958014 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02010263 0,03954778 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02010263 0,03951547 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02010263 0,03948321 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02010263 0,03945101 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02010263 0,03941886 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02010263 0,03938676 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02010263 0,03935471 ! ribosome assembly GO:0042255 17 13 0,000 0,02010263 0,03932271 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02010263 0,03929077 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02010263 0,03925888 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02010263 0,03922704 ! chromatin silencing GO:0006342 26 13 0,000 0,02010263 0,03919525 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02010263 0,03916351 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02010263 0,03913183 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02010263 0,03910019 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02010263 0,03906861 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02010263 0,03903708 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02010263 0,03900559 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02010263 0,03897416 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02010263 0,03894278 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02010263 0,03891145 ! embryonic placenta development GO:0001892 23 13 0,000 0,02010263 0,03888017 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02010263 0,03884895 ! insulin secretion GO:0030073 23 13 0,000 0,02010263 0,03881777 ! actin filament polymerization GO:0030041 24 13 0,000 0,02010263 0,03878664 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02010263 0,03875556 ! acrosome reaction GO:0007340 18 13 0,000 0,02010263 0,03872453 ! rRNA transcription GO:0009303 25 14 0,000 0,0216325 0,04163824 ! lactation GO:0007595 26 14 0,000 0,0216325 0,04160496 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0216325 0,04157173 ! reproductive cellular process GO:0048610 20 14 0,000 0,0216325 0,04153855 ! tRNA modification GO:0006400 20 14 0,000 0,0216325 0,04150542 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0216325 0,04147235 ! regulation of S phase GO:0033261 23 14 0,000 0,0216325 0,04143933 ! water transport GO:0006833 21 14 0,000 0,0216325 0,04140637 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0216325 0,04137345 ! non-recombinational repair GO:0000726 25 14 0,000 0,0216325 0,04134059 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0216325 0,04130778 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0216325 0,04127502 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0216325 0,04124231 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0216325 0,04120966 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0216325 0,04117706 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0216325 0,04114451 ! palate development GO:0060021 31 14 0,000 0,0216325 0,04111201 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0216325 0,04107956 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0216325 0,04104716 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0216325 0,04101482 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0216325 0,04098252 ! arginine metabolic process GO:0006525 17 14 0,000 0,0216325 0,04095028 ! regulation of heart rate GO:0002027 24 14 0,000 0,0216325 0,04091808 ! organic alcohol transport GO:0015850 29 14 0,000 0,0216325 0,04088594 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0216325 0,04085385 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0216325 0,04082181 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0216325 0,04078981 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0216325 0,04075787 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0216325 0,04072598 ! L-amino acid transport GO:0015807 30 14 0,000 0,0216325 0,04069414 ! bone mineralization GO:0030282 17 14 0,000 0,0216325 0,04066234 ! stem cell development GO:0048864 43 14 0,000 0,0216325 0,0406306 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0216325 0,04059891 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0216325 0,04056727 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0216325 0,04053567 ! cerebellum development GO:0021549 21 14 0,000 0,0216325 0,04050413 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0216325 0,04047263 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0216325 0,04044118 ! response to gamma radiation GO:0010332 28 14 0,000 0,0216325 0,04040978 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0216325 0,04037843 ! cofactor transport GO:0051181 26 14 0,000 0,0216325 0,04034713 ! NADP metabolic process GO:0006739 24 14 0,000 0,0216325 0,04031588 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0216325 0,04028468 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0216325 0,04025352 ! intestinal absorption GO:0050892 25 14 0,000 0,0216325 0,04022241 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0216325 0,04019135 ! oxygen transport GO:0015671 21 14 0,000 0,0216325 0,04016034 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0216325 0,04012938 ! male genitalia development GO:0030539 24 14 0,000 0,0216325 0,04009846 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0216325 0,04006759 ! regulation of axon extension GO:0030516 37 14 0,000 0,0216325 0,04003677 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,0216325 0,040006 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0216325 0,03997527 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02316003 0,04276519 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02316003 0,04273239 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02316003 0,04269965 ! superoxide anion generation GO:0042554 20 15 0,000 0,02316003 0,04266695 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02316003 0,04263431 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02316003 0,04260171 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02316003 0,04256917 ! copper ion transport GO:0006825 20 15 0,000 0,02316003 0,04253667 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02316003 0,04250423 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02316003 0,04247183 ! sulfate transport GO:0008272 23 15 0,000 0,02316003 0,04243948 ! response to cAMP GO:0051591 22 15 0,000 0,02316003 0,04240719 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02316003 0,04237494 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02316003 0,04234274 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02316003 0,04231059 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02316003 0,04227848 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02316003 0,04224643 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02316003 0,04221443 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02316003 0,04218247 ! pituitary gland development GO:0021983 29 15 0,000 0,02316003 0,04215056 ! vesicle coating GO:0006901 33 15 0,000 0,02316003 0,0421187 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02316003 0,04208689 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02316003 0,04205513 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02316003 0,04202341 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02316003 0,04199174 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02316003 0,04196012 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02316003 0,04192855 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02316003 0,04189702 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02316003 0,04186555 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02316003 0,04183412 ! histone deacetylation GO:0016575 20 15 0,000 0,02316003 0,04180273 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02316003 0,0417714 ! tissue regeneration GO:0042246 26 15 0,000 0,02316003 0,04174011 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02316003 0,04170886 ! water homeostasis GO:0030104 27 15 0,000 0,02316003 0,04167767 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02316003 0,04164652 ! muscle maintenance GO:0046716 26 15 0,000 0,02316003 0,04161542 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02316003 0,04158436 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02316003 0,04155335 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02316003 0,04152239 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02316003 0,04149147 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02316003 0,0414606 ! cell killing GO:0001906 29 15 0,000 0,02316003 0,04142977 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02316003 0,04139899 ! detection of bacterium GO:0016045 18 15 0,000 0,02316003 0,04136826 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02316003 0,04133757 ! peptide hormone processing GO:0016486 23 15 0,000 0,02316003 0,04130692 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02468523 0,04399457 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02468523 0,043962 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02468523 0,04392949 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02468523 0,04389702 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02468523 0,0438646 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02468523 0,04383223 ! bone remodeling GO:0046849 27 16 0,000 0,02468523 0,0437999 ! filopodium assembly GO:0046847 32 16 0,000 0,02468523 0,04376762 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02468523 0,04373539 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02468523 0,04370321 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02468523 0,04367108 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02468523 0,04363899 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02468523 0,04360695 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02468523 0,04357496 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02468523 0,04354301 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02468523 0,04351111 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02468523 0,04347926 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02468523 0,04344745 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02468523 0,04341569 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02468523 0,04338398 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02468523 0,04335231 ! response to osmotic stress GO:0006970 25 16 0,000 0,02468523 0,04332069 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02468523 0,04328911 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02468523 0,04325759 ! fructose metabolic process GO:0006000 25 16 0,000 0,02468523 0,0432261 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02468523 0,04319467 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02468523 0,04316327 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02468523 0,04313193 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02468523 0,04310063 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02468523 0,04306937 ! axon cargo transport GO:0008088 43 16 0,000 0,02468523 0,04303816 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02468523 0,043007 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02468523 0,04297588 ! DNA replication initiation GO:0006270 27 16 0,000 0,02468523 0,04294481 ! neuron recognition GO:0008038 35 16 0,000 0,02468523 0,04291378 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02468523 0,04288279 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02468523 0,04285185 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02468523 0,04282096 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02468523 0,0427901 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02468523 0,0427593 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02468523 0,04272854 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02468523 0,04269782 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02468523 0,04266714 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02468523 0,04263652 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02468523 0,04260593 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02468523 0,04257539 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02468523 0,04254489 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02468523 0,04251443 ! defense response to virus GO:0051607 37 16 0,000 0,02468523 0,04248402 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0262081 0,04507268 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0262081 0,04504049 ! metencephalon development GO:0022037 30 17 0,000 0,0262081 0,04500834 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0262081 0,04497623 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0262081 0,04494418 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0262081 0,04491217 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0262081 0,0448802 ! signal complex assembly GO:0007172 41 17 0,000 0,0262081 0,04484828 ! endothelial cell migration GO:0043542 28 17 0,000 0,0262081 0,0448164 ! inositol metabolic process GO:0006020 28 17 0,000 0,0262081 0,04478457 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0262081 0,04475279 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0262081 0,04472105 ! glial cell development GO:0021782 27 17 0,000 0,0262081 0,04468936 ! limbic system development GO:0021761 36 17 0,000 0,0262081 0,04465771 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0262081 0,0446261 ! adult walking behavior GO:0007628 33 17 0,000 0,0262081 0,04459454 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0262081 0,04456303 ! heart looping GO:0001947 30 17 0,000 0,0262081 0,04453155 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0262081 0,04450013 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0262081 0,04446875 ! myoblast differentiation GO:0045445 45 17 0,000 0,0262081 0,04443741 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0262081 0,04440611 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0262081 0,04437486 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,0262081 0,04434366 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0262081 0,0443125 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0262081 0,04428138 ! glycine metabolic process GO:0006544 28 17 0,000 0,0262081 0,0442503 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,0262081 0,04421927 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0262081 0,04418828 ! NAD metabolic process GO:0019674 29 17 0,000 0,0262081 0,04415734 ! membrane budding GO:0006900 37 17 0,000 0,0262081 0,04412644 ! DNA integration GO:0015074 29 17 0,000 0,0262081 0,04409558 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0262081 0,04406477 ! regulation of protein binding GO:0043393 33 17 0,000 0,0262081 0,044034 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0262081 0,04400327 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0262081 0,04397258 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0262081 0,04394194 ! genitalia development GO:0048806 30 17 0,000 0,0262081 0,04391134 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,0262081 0,04388078 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0262081 0,04385027 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0262081 0,04381979 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0262081 0,04378936 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0262081 0,04375897 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0262081 0,04372863 ! steroid catabolic process GO:0006706 31 17 0,000 0,0262081 0,04369832 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0262081 0,04366806 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,0262081 0,04363784 ! gas transport GO:0015669 25 17 0,000 0,0262081 0,04360766 ! organic cation transport GO:0015695 31 17 0,000 0,0262081 0,04357753 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0262081 0,04354743 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0262081 0,04351738 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0262081 0,04348737 ! microspike assembly GO:0030035 36 17 0,000 0,0262081 0,0434574 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0262081 0,04342747 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0262081 0,04339758 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02772864 0,04588384 ! neuron maturation GO:0042551 42 18 0,000 0,02772864 0,0458523 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02772864 0,04582081 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02772864 0,04578936 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02772864 0,04575795 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02772864 0,04572659 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02772864 0,04569527 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02772864 0,045664 ! memory GO:0007613 31 18 0,000 0,02772864 0,04563276 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02772864 0,04560157 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02772864 0,04557042 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02772864 0,04553932 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02772864 0,04550825 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02772864 0,04547723 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02772864 0,04544625 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02772864 0,04541532 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02772864 0,04538442 ! response to retinoic acid GO:0032526 26 18 0,000 0,02772864 0,04535357 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02772864 0,04532276 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02772864 0,04529199 ! response to fungus GO:0009620 21 18 0,000 0,02772864 0,04526126 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02772864 0,04523057 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02772864 0,04519993 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02772864 0,04516933 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02772864 0,04513877 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02772864 0,04510825 ! vitamin transport GO:0051180 27 18 0,000 0,02772864 0,04507777 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02772864 0,04504733 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02772864 0,04501694 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02772864 0,04498658 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02772864 0,04495627 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02772864 0,04492599 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02772864 0,04489576 ! nerve development GO:0021675 28 18 0,000 0,02772864 0,04486557 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02772864 0,04483542 ! protein secretion GO:0009306 39 19 0,000 0,02924685 0,04725851 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02924685 0,04722679 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02924685 0,04719512 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02924685 0,04716349 ! skin development GO:0043588 36 19 0,000 0,02924685 0,0471319 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02924685 0,04710035 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02924685 0,04706885 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02924685 0,04703738 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02924685 0,04700596 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02924685 0,04697458 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02924685 0,04694324 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02924685 0,04691195 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02924685 0,0468807 ! cerebral cortex development GO:0021987 36 19 0,000 0,02924685 0,04684948 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,02924685 0,04681831 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,02924685 0,04678718 ! heme metabolic process GO:0042168 36 19 0,000 0,02924685 0,0467561 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02924685 0,04672505 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02924685 0,04669404 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02924685 0,04666308 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02924685 0,04663216 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02924685 0,04660127 ! peptide cross-linking GO:0018149 37 19 0,000 0,02924685 0,04657043 ! protein export from nucleus GO:0006611 36 19 0,000 0,02924685 0,04653963 ! heart process GO:0003015 30 19 0,000 0,02924685 0,04650887 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02924685 0,04647815 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02924685 0,04644747 ! visual learning GO:0008542 36 19 0,000 0,02924685 0,04641684 ! cellular pigmentation GO:0033059 36 19 0,000 0,02924685 0,04638624 ! G1 phase GO:0051318 40 19 0,000 0,02924685 0,04635568 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02924685 0,04632516 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02924685 0,04629469 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02924685 0,04626425 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02924685 0,04623385 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02924685 0,0462035 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02924685 0,04617318 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02924685 0,0461429 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02924685 0,04611266 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02924685 0,04608246 ! cilium assembly GO:0042384 37 19 0,000 0,02924685 0,04605231 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02924685 0,04602219 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03076275 0,04837593 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03076275 0,04834433 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03076275 0,04831277 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03076275 0,04828126 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03076275 0,04824978 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03076275 0,04821835 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03076275 0,04818696 ! response to vitamin GO:0033273 31 20 0,000 0,03076275 0,04815561 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03076275 0,0481243 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03076275 0,04809303 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03076275 0,0480618 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03076275 0,04803061 ! response to alkaloid GO:0043279 38 20 0,000 0,03076275 0,04799946 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03076275 0,04796835 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03076275 0,04793728 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03076275 0,04790626 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03076275 0,04787527 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03076275 0,04784432 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03076275 0,04781341 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03076275 0,04778255 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,03076275 0,04775172 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03076275 0,04772093 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03076275 0,04769018 ! body fluid secretion GO:0007589 31 20 0,000 0,03076275 0,04765948 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03076275 0,04762881 ! peptide secretion GO:0002790 35 20 0,000 0,03076275 0,04759818 ! stem cell differentiation GO:0048863 53 20 0,000 0,03076275 0,04756759 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03076275 0,04753704 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,03076275 0,04750652 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03076275 0,04747605 ! sensory perception of pain GO:0019233 30 20 0,000 0,03076275 0,04744562 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03076275 0,04741522 ! diencephalon development GO:0021536 34 20 0,000 0,03076275 0,04738487 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03076275 0,04735455 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03076275 0,04732427 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03076275 0,04729404 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03076275 0,04726384 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03076275 0,04723367 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03076275 0,04720355 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03076275 0,04717346 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03076275 0,04714342 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03076275 0,04711341 ! regulation of glucose import GO:0046324 29 20 0,000 0,03076275 0,04708344 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03076275 0,04705351 ! actin filament-based movement GO:0030048 43 20 0,000 0,03076275 0,04702361 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03076275 0,04699376 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03076275 0,04696394 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03076275 0,04693416 ! negative regulation of translation GO:0017148 29 20 0,000 0,03076275 0,04690441 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03076275 0,04687471 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03076275 0,04684504 ! regulation of cell killing GO:0031341 42 21 0,000 0,03227632 0,04911881 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03227632 0,04908776 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03227632 0,04905675 ! hormone secretion GO:0046879 38 21 0,000 0,03227632 0,04902578 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03227632 0,04899485 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03227632 0,04896396 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03227632 0,0489331 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03227632 0,04890229 ! axis specification GO:0009798 38 21 0,000 0,03227632 0,04887151 ! ovarian follicle development GO:0001541 35 21 0,000 0,03227632 0,04884078 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03227632 0,04881008 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03227632 0,04877942 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03227632 0,0487488 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03227632 0,04871821 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03227632 0,04868767 ! cell aging GO:0007569 44 21 0,000 0,03227632 0,04865716 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03227632 0,0486267 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03227632 0,04859627 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03227632 0,04856587 ! cytolysis GO:0019835 24 21 0,000 0,03227632 0,04853552 ! vasodilation GO:0042311 39 21 0,000 0,03227632 0,04850521 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03227632 0,04847493 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03227632 0,04844469 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03227632 0,04841449 ! oogenesis GO:0048477 36 21 0,000 0,03227632 0,04838432 ! DNA modification GO:0006304 34 21 0,000 0,03227632 0,04835419 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03227632 0,0483241 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03227632 0,04829405 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03227632 0,04826404 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03227632 0,04823406 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03227632 0,04820412 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03227632 0,04817421 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03227632 0,04814435 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03227632 0,04811452 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03227632 0,04808473 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03227632 0,04805497 ! collagen catabolic process GO:0030574 28 21 0,000 0,03227632 0,04802525 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03227632 0,04799557 ! gut development GO:0048565 39 21 0,000 0,03227632 0,04796593 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03378759 0,05018082 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03378759 0,05014987 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03378759 0,05011895 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03378759 0,05008807 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03378759 0,05005723 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03378759 0,05002642 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03378759 0,04999566 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03378759 0,04996493 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03378759 0,04993424 ! regeneration GO:0031099 41 22 0,000 0,03378759 0,04990358 ! keratinization GO:0031424 28 22 0,000 0,03378759 0,04987297 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03378759 0,04984239 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03378759 0,04981185 ! sensory perception of taste GO:0050909 28 22 0,000 0,03378759 0,04978134 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03378759 0,04975088 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03378759 0,04972045 ! vacuolar transport GO:0007034 36 22 0,000 0,03378759 0,04969006 ! lysosome organization GO:0007040 41 22 0,000 0,03378759 0,0496597 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03378759 0,04962939 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03378759 0,04959911 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03378759 0,04956886 ! fucose metabolic process GO:0006004 39 22 0,000 0,03378759 0,04953866 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03378759 0,04950849 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03378759 0,04947835 ! ureteric bud development GO:0001657 43 22 0,000 0,03378759 0,04944826 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03378759 0,0494182 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03378759 0,04938818 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03378759 0,04935819 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03378759 0,04932824 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03378759 0,04929832 ! sarcomere organization GO:0045214 30 22 0,000 0,03378759 0,04926845 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,03378759 0,0492386 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03378759 0,0492088 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03378759 0,04917903 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03378759 0,0491493 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,03378759 0,0491196 ! protein stabilization GO:0050821 39 22 0,000 0,03378759 0,04908994 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03529654 0,05125135 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03529654 0,05122043 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03529654 0,05118956 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03529654 0,05115872 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03529654 0,05112792 ! gluconeogenesis GO:0006094 33 23 0,000 0,03529654 0,05109716 ! viral genome replication GO:0019079 41 23 0,000 0,03529654 0,05106643 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03529654 0,05103575 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03529654 0,05100509 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03529654 0,05097448 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03529654 0,0509439 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03529654 0,05091336 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03529654 0,05088285 ! visual behavior GO:0007632 42 23 0,000 0,03529654 0,05085238 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03529654 0,05082195 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03529654 0,05079156 ! response to ethanol GO:0045471 46 23 0,000 0,03529654 0,0507612 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03529654 0,05073087 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03529654 0,05070059 ! peroxisome organization GO:0007031 37 23 0,000 0,03529654 0,05067033 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03529654 0,05064012 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03529654 0,05060994 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03529654 0,0505798 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03529654 0,05054969 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03529654 0,05051962 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03529654 0,05048958 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03529654 0,05045958 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03529654 0,05042962 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03529654 0,05039969 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03529654 0,0503698 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03529654 0,05033994 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03529654 0,05031012 ! fatty acid transport GO:0015908 44 23 0,000 0,03529654 0,05028033 ! platelet activation GO:0030168 37 23 0,000 0,03529654 0,05025058 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03529654 0,05022086 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03529654 0,05019118 ! hormone transport GO:0009914 40 23 0,000 0,03529654 0,05016154 ! cell-cell recognition GO:0009988 25 23 0,000 0,03529654 0,05013192 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03529654 0,05010235 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03529654 0,05007281 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03529654 0,0500433 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03529654 0,05001383 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03529654 0,04998439 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03680319 0,05208734 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03680319 0,05205672 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03680319 0,05202613 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03680319 0,05199558 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03680319 0,05196507 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03680319 0,05193459 ! vesicle docking GO:0048278 47 24 0,000 0,03680319 0,05190415 ! spinal cord development GO:0021510 47 24 0,000 0,03680319 0,05187374 ! vacuole organization GO:0007033 43 24 0,000 0,03680319 0,05184337 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03680319 0,05181303 ! digestive system process GO:0022600 39 24 0,000 0,03680319 0,05178273 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03680319 0,05175247 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03680319 0,05172224 ! regulation of behavior GO:0050795 43 24 0,000 0,03680319 0,05169205 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03680319 0,05166189 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03680319 0,05163176 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03680319 0,05160168 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03680319 0,05157162 ! membrane depolarization GO:0051899 39 24 0,000 0,03680319 0,0515416 ! pallium development GO:0021543 49 24 0,000 0,03680319 0,05151162 ! pentose metabolic process GO:0019321 35 24 0,000 0,03680319 0,05148167 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03680319 0,05145176 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03680319 0,05142188 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03680319 0,05139203 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03680319 0,05136222 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03680319 0,05133245 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03680319 0,05130271 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03680319 0,051273 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03680319 0,05124333 ! regulation of amine transport GO:0051952 40 24 0,000 0,03680319 0,05121369 ! protein tetramerization GO:0051262 52 24 0,000 0,03680319 0,05118409 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03830753 0,05324548 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,03830753 0,05321474 ! myelination GO:0042552 45 25 0,000 0,03830753 0,05318403 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03830753 0,05315336 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03830753 0,05312273 ! phototransduction GO:0007602 33 25 0,000 0,03830753 0,05309213 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03830753 0,05306156 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03830753 0,05303103 ! sperm motility GO:0030317 31 25 0,000 0,03830753 0,05300053 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03830753 0,05297007 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03830753 0,05293965 ! receptor metabolic process GO:0043112 46 25 0,000 0,03830753 0,05290926 ! chromosome condensation GO:0030261 45 25 0,000 0,03830753 0,0528789 ! response to starvation GO:0042594 42 25 0,000 0,03830753 0,05284858 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03830753 0,0528183 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,03830753 0,05278805 ! neural crest cell development GO:0014032 54 25 0,000 0,03830753 0,05275783 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03830753 0,05272765 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03830753 0,0526975 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03830753 0,05266739 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03830753 0,05263731 ! interaction with host GO:0051701 62 25 0,000 0,03830753 0,05260727 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03830753 0,05257726 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03830753 0,05254728 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03830753 0,05251734 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03830753 0,05248743 ! immunoglobulin production GO:0002377 55 25 0,000 0,03830753 0,05245756 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03830753 0,05242772 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03830753 0,05239791 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03830753 0,05236814 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03830753 0,0523384 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03830753 0,0523087 ! telomere organization GO:0032200 43 25 0,000 0,03830753 0,05227903 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03830753 0,05224939 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03830753 0,05221979 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03980958 0,05423661 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03980958 0,05420591 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03980958 0,05417525 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03980958 0,05414463 ! initiation of viral infection GO:0019059 57 26 0,000 0,03980958 0,05411404 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03980958 0,05408348 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03980958 0,05405296 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03980958 0,05402248 ! molting cycle process GO:0022404 50 26 0,000 0,03980958 0,05399202 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03980958 0,05396161 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03980958 0,05393122 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03980958 0,05390087 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03980958 0,05387056 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03980958 0,05384028 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03980958 0,05381003 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03980958 0,05377981 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,03980958 0,05374964 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03980958 0,05371949 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03980958 0,05368938 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03980958 0,0536593 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03980958 0,05362926 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03980958 0,05359924 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03980958 0,05356927 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03980958 0,05353932 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03980958 0,05350941 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03980958 0,05347954 ! blastocyst development GO:0001824 49 26 0,000 0,03980958 0,05344969 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03980958 0,05341988 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03980958 0,05339011 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03980958 0,05336036 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,04130933 0,05533978 ! neuron fate commitment GO:0048663 48 27 0,000 0,04130933 0,05530899 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04130933 0,05527822 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04130933 0,0552475 ! iron ion transport GO:0006826 59 27 0,000 0,04130933 0,0552168 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,04130933 0,05518614 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04130933 0,05515552 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04130933 0,05512493 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04130933 0,05509437 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04130933 0,05506385 ! fat cell differentiation GO:0045444 50 27 0,000 0,04130933 0,05503336 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04130933 0,0550029 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04130933 0,05497248 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04130933 0,05494209 ! autophagy GO:0006914 41 27 0,000 0,04130933 0,05491174 ! male gonad development GO:0008584 44 27 0,000 0,04130933 0,05488142 ! response to toxin GO:0009636 47 27 0,000 0,04130933 0,05485113 ! primary neural tube formation GO:0014020 51 27 0,000 0,04130933 0,05482087 ! base-excision repair GO:0006284 41 27 0,000 0,04130933 0,05479065 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04130933 0,05476047 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04130933 0,05473031 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04130933 0,05470019 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04130933 0,0546701 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04130933 0,05464005 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04130933 0,05461003 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04130933 0,05458004 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04130933 0,05455008 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04280679 0,0564965 ! circadian rhythm GO:0007623 50 28 0,000 0,04280679 0,05646553 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04280679 0,05643459 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04280679 0,05640368 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04280679 0,05637281 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04280679 0,05634197 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,04280679 0,05631117 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04280679 0,0562804 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04280679 0,05624966 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04280679 0,05621896 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04280679 0,05618828 ! synaptogenesis GO:0007416 42 28 0,000 0,04280679 0,05615765 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,04280679 0,05612704 ! lipid oxidation GO:0034440 43 28 0,000 0,04280679 0,05609647 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04280679 0,05606594 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04280679 0,05603543 ! translational initiation GO:0006413 65 29 0,000 0,04430195 0,05796112 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,04430195 0,05792962 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04430195 0,05789815 ! regulation of pH GO:0006885 43 29 0,000 0,04430195 0,05786672 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04430195 0,05783532 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04430195 0,05780396 ! catechol metabolic process GO:0009712 54 29 0,000 0,04430195 0,05777263 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,04430195 0,05774133 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,04430195 0,05771007 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,04430195 0,05767884 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04430195 0,05764765 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,04430195 0,05761649 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04430195 0,05758536 ! cell fate determination GO:0001709 60 29 0,000 0,04430195 0,05755426 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04430195 0,0575232 ! detection of light stimulus GO:0009583 38 29 0,000 0,04430195 0,05749218 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,04430195 0,05746119 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,04430195 0,05743023 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,04430195 0,0573993 ! tissue homeostasis GO:0001894 48 29 0,000 0,04430195 0,05736841 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,04430195 0,05733755 ! phenol metabolic process GO:0018958 55 30 0,000 0,04579483 0,05923783 ! zinc ion transport GO:0006829 45 30 0,000 0,04579483 0,059206 ! membrane docking GO:0022406 61 30 0,000 0,04579483 0,05917421 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04579483 0,05914244 ! cell junction assembly GO:0034329 78 30 0,000 0,04579483 0,05911071 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04579483 0,05907902 ! acute-phase response GO:0006953 49 30 0,000 0,04579483 0,05904736 ! myofibril assembly GO:0030239 47 30 0,000 0,04579483 0,05901573 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,04579483 0,05898414 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04579483 0,05895258 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04579483 0,05892105 ! phospholipid transport GO:0015914 51 30 0,000 0,04579483 0,05888956 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04579483 0,0588581 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04579483 0,05882668 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04579483 0,05879529 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04579483 0,05876393 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04579483 0,05873261 ! eye morphogenesis GO:0048592 60 30 0,000 0,04579483 0,05870132 ! regulation of B cell activation GO:0050864 50 30 0,000 0,04579483 0,05867006 ! response to heat GO:0009408 50 30 0,000 0,04579483 0,05863883 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04728543 0,06051529 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04728543 0,06048312 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04728543 0,06045098 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04728543 0,06041888 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04728543 0,06038681 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04728543 0,06035477 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,04728543 0,06032277 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04728543 0,06029081 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04728543 0,06025887 ! ovulation cycle process GO:0022602 49 31 0,000 0,04728543 0,06022697 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04728543 0,06019511 ! peptide transport GO:0015833 55 31 0,000 0,04728543 0,06016327 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04728543 0,06013148 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04728543 0,06009971 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04728543 0,06006798 ! mesoderm formation GO:0001707 69 31 0,000 0,04728543 0,06003628 ! natural killer cell activation GO:0030101 45 31 0,000 0,04728543 0,06000462 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04728543 0,05997298 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04728543 0,05994139 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04728543 0,05990982 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04728543 0,05987829 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04728543 0,05984679 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04877375 0,06169803 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04877375 0,06166561 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04877375 0,06163322 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04877375 0,06160086 ! cholesterol transport GO:0030301 56 32 0,000 0,04877375 0,06156855 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04877375 0,06153626 ! spliceosome assembly GO:0000245 67 32 0,000 0,04877375 0,06150401 ! spindle organization GO:0007051 46 32 0,000 0,04877375 0,06147179 ! metanephros development GO:0001656 74 32 0,000 0,04877375 0,06143961 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04877375 0,06140746 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04877375 0,06137534 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04877375 0,06134326 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04877375 0,06131121 ! muscle cell development GO:0055001 49 32 0,000 0,04877375 0,06127919 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04877375 0,06124721 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04877375 0,06121526 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,04877375 0,06118334 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,04877375 0,06115146 ! ovulation cycle GO:0042698 51 32 0,000 0,04877375 0,06111961 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04877375 0,06108779 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04877375 0,06105601 ! hindbrain development GO:0030902 61 32 0,000 0,04877375 0,06102426 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04877375 0,06099254 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04877375 0,06096086 ! gene silencing GO:0016458 65 32 0,000 0,04877375 0,0609292 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0502598 0,06275302 ! post-embryonic development GO:0009791 69 33 0,000 0,0502598 0,06272047 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0502598 0,06268796 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0502598 0,06265548 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0502598 0,06262303 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0502598 0,06259062 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0502598 0,06255824 ! cell fate specification GO:0001708 52 33 0,000 0,0502598 0,06252589 ! sterol transport GO:0015918 57 33 0,000 0,0502598 0,06249358 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0502598 0,0624613 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0502598 0,06242905 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0502598 0,06239684 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0502598 0,06236466 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,05174357 0,06417269 ! glial cell differentiation GO:0010001 63 34 0,000 0,05174357 0,06413963 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,05174357 0,0641066 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,05174357 0,06407361 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,05174357 0,06404065 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,05174357 0,06400772 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,05174357 0,06397483 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,05174357 0,06394197 ! mismatch repair GO:0006298 46 34 0,000 0,05174357 0,06390915 ! spermatid development GO:0007286 63 34 0,000 0,05174357 0,06387636 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,05174357 0,0638436 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,05174357 0,06381088 ! placenta development GO:0001890 53 34 0,000 0,05174357 0,06377819 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,05174357 0,06374553 ! regulation of muscle development GO:0048634 70 35 0,000 0,05322507 0,06553711 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,05322507 0,06550359 ! negative regulation of secretion GO:0051048 63 35 0,000 0,05322507 0,0654701 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,05322507 0,06543665 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,05322507 0,06540323 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,05322507 0,06536984 ! odontogenesis GO:0042476 66 35 0,000 0,05322507 0,06533649 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,05322507 0,06530317 ! female gonad development GO:0008585 58 35 0,000 0,05322507 0,06526989 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,05322507 0,06523664 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,05322507 0,06520342 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,05322507 0,06517024 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,05322507 0,06513709 ! cytokine production GO:0001816 59 35 0,000 0,05322507 0,06510398 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,05322507 0,06507089 ! neural tube formation GO:0001841 67 35 0,000 0,05322507 0,06503785 ! vesicle localization GO:0051648 64 35 0,000 0,05322507 0,06500483 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,05470431 0,06677756 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,05470431 0,06674369 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,05470431 0,06670987 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,05470431 0,06667607 ! cell junction organization GO:0034330 86 36 0,000 0,05470431 0,06664231 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,05470431 0,06660859 ! positive regulation of cell development GO:0010720 80 36 0,000 0,05470431 0,06657489 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,05470431 0,06654124 ! regulation of proteolysis GO:0030162 72 36 0,000 0,05470431 0,06650761 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,05470431 0,06647402 ! aerobic respiration GO:0009060 55 36 0,000 0,05470431 0,06644047 ! embryonic organ development GO:0048568 57 36 0,000 0,05470431 0,06640695 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,05470431 0,06637346 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,05470431 0,06634 ! RNA export from nucleus GO:0006405 56 37 0,000 0,05618128 0,06809681 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05618128 0,06806252 ! meiosis I GO:0007127 65 37 0,000 0,05618128 0,06802827 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05618128 0,06799405 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05618128 0,06795986 ! organic anion transport GO:0015711 68 37 0,000 0,05618128 0,06792571 ! tissue remodeling GO:0048771 76 37 0,000 0,05618128 0,0678916 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05618128 0,06785751 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05618128 0,06782347 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05618128 0,06778945 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,05618128 0,06775547 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05618128 0,06772153 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05618128 0,06768762 ! glycogen metabolic process GO:0005977 61 37 0,000 0,05618128 0,06765374 ! spermatid differentiation GO:0048515 66 37 0,000 0,05618128 0,06761989 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,05618128 0,06758608 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,057656 0,06932551 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,057656 0,06929088 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,057656 0,06925628 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,057656 0,06922173 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,057656 0,0691872 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,057656 0,06915271 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,057656 0,06911825 ! lipid homeostasis GO:0055088 67 38 0,000 0,057656 0,06908383 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,057656 0,06904945 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,057656 0,06901509 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,057656 0,06898077 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,057656 0,06894649 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,057656 0,06891224 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,057656 0,06887802 ! glucan metabolic process GO:0044042 62 38 0,000 0,057656 0,06884384 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,05912846 0,070567 ! mammary gland development GO:0030879 86 39 0,000 0,05912846 0,07053202 ! learning GO:0007612 77 39 0,000 0,05912846 0,07049707 ! ear morphogenesis GO:0042471 60 39 0,000 0,05912846 0,07046215 ! organic ether metabolic process GO:0018904 55 39 0,000 0,05912846 0,07042727 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05912846 0,07039242 ! segmentation GO:0035282 67 39 0,000 0,05912846 0,07035761 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05912846 0,07032283 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05912846 0,07028808 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05912846 0,07025337 ! RNA modification GO:0009451 57 39 0,000 0,05912846 0,0702187 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05912846 0,07018405 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,06059867 0,07189369 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,06059867 0,07185826 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,06059867 0,07182286 ! feeding behavior GO:0007631 59 40 0,000 0,06059867 0,0717875 ! negative regulation of binding GO:0051100 72 40 0,000 0,06059867 0,07175217 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,06059867 0,07171687 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,06059867 0,07168161 ! cytokinesis GO:0000910 72 40 0,000 0,06059867 0,07164639 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06206663 0,07334593 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06206663 0,07330993 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06206663 0,07327395 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06206663 0,07323802 ! gliogenesis GO:0042063 88 41 0,000 0,06206663 0,07320212 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06206663 0,07316625 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06206663 0,07313042 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,06206663 0,07309462 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06206663 0,07305886 ! female gamete generation GO:0007292 61 41 0,000 0,06206663 0,07302314 ! polyol metabolic process GO:0019751 66 41 0,000 0,06206663 0,07298745 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06206663 0,07295179 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06353235 0,0746381 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06353235 0,07460167 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,06353235 0,07456528 ! regulation of tube size GO:0035150 71 42 0,000 0,06353235 0,07452893 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06353235 0,07449261 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,06353235 0,07445632 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,06353235 0,07442007 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,06353235 0,07438386 ! neuron migration GO:0001764 79 42 0,000 0,06353235 0,07434768 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06353235 0,07431154 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,06353235 0,07427543 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,06499582 0,07594946 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,06499582 0,0759126 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,06499582 0,07587576 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,06499582 0,07583897 ! glucose transport GO:0015758 65 43 0,000 0,06499582 0,0758022 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,06499582 0,07576548 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,06499582 0,07572879 ! neural tube development GO:0021915 77 43 0,000 0,06499582 0,07569213 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,06499582 0,07565551 ! striated muscle contraction GO:0006941 77 43 0,000 0,06499582 0,07561893 ! phagocytosis GO:0006909 90 43 0,000 0,06499582 0,07558238 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,06499582 0,07554587 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,06645706 0,07720699 ! hexose transport GO:0008645 67 44 0,000 0,06645706 0,07716973 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,06645706 0,0771325 ! male sex differentiation GO:0046661 76 44 0,000 0,06645706 0,07709531 ! double-strand break repair GO:0006302 81 44 0,000 0,06645706 0,07705816 ! biopolymer methylation GO:0043414 84 44 0,000 0,06645706 0,07702104 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,06645706 0,07698396 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,06645706 0,07694691 ! developmental growth GO:0048589 82 44 0,000 0,06645706 0,0769099 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,06791606 0,07856059 ! glycolysis GO:0006096 65 45 0,000 0,06791606 0,07852284 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,06791606 0,07848513 ! leukocyte migration GO:0050900 68 45 0,000 0,06791606 0,07844745 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,06791606 0,07840981 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,06791606 0,0783722 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,06791606 0,07833463 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,06791606 0,07829709 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,06791606 0,0782596 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,06791606 0,07822213 ! cell growth GO:0016049 84 45 0,000 0,06791606 0,07818471 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,06937283 0,07982354 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,06937283 0,07978538 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,06937283 0,07974726 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,06937283 0,07970918 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,06937283 0,07967113 ! response to insulin stimulus GO:0032868 95 46 0,000 0,06937283 0,07963312 ! positive regulation of defense response GO:0031349 76 47 0,000 0,07082737 0,08126402 ! response to calcium ion GO:0051592 81 47 0,000 0,07082737 0,08122528 ! endosome transport GO:0016197 108 47 0,000 0,07082737 0,08118659 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,07082737 0,08114793 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,07082737 0,0811093 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,07082737 0,08107072 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,07082737 0,08103217 ! JNK cascade GO:0007254 91 47 0,000 0,07082737 0,08099365 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,07082737 0,08095518 ! methylation GO:0032259 90 47 0,000 0,07082737 0,08091674 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,07227968 0,08253674 ! mitochondrial transport GO:0006839 82 48 0,000 0,07227968 0,08249759 ! Notch signaling pathway GO:0007219 96 48 0,000 0,07227968 0,08245847 ! cellular component disassembly GO:0022411 86 48 0,000 0,07227968 0,08241939 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,07227968 0,08238035 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,07227968 0,08234134 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,07227968 0,08230237 ! activation of caspase activity GO:0006919 84 48 0,000 0,07227968 0,08226344 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,07227968 0,08222455 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,07227968 0,08218569 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,07227968 0,08214687 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,07227968 0,08210808 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07372978 0,08371583 ! regulation of action potential GO:0001508 95 49 0,000 0,07372978 0,08367634 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,07372978 0,08363689 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07372978 0,08359747 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,07372978 0,0835581 ! peptide metabolic process GO:0006518 76 49 0,000 0,07372978 0,08351876 ! response to temperature stimulus GO:0009266 76 49 0,000 0,07372978 0,08347945 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07372978 0,08344019 ! endocrine system development GO:0035270 104 49 0,000 0,07372978 0,08340096 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,07372978 0,08336177 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07372978 0,08332261 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07372978 0,08328349 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07517765 0,08487913 ! regulation of ossification GO:0030278 117 50 0,000 0,07517765 0,08483932 ! inner ear development GO:0048839 79 50 0,000 0,07517765 0,08479954 ! histone modification GO:0016570 91 50 0,000 0,07517765 0,08475981 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,07517765 0,08472011 ! positive regulation of binding GO:0051099 78 51 0,000 0,07662331 0,08630884 ! viral infectious cycle GO:0019058 99 51 0,000 0,07662331 0,08626845 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,07662331 0,0862281 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,07662331 0,08618779 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,07662331 0,08614752 ! excretion GO:0007588 83 51 0,000 0,07662331 0,08610728 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,07662331 0,08606708 ! vesicle organization GO:0016050 107 51 0,000 0,07662331 0,08602692 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,07662331 0,08598679 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,07662331 0,08594671 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,07662331 0,08590666 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,07806676 0,08748422 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,07806676 0,08744349 ! membrane fusion GO:0006944 110 52 0,000 0,07806676 0,0874028 ! positive regulation of growth GO:0045927 90 52 0,000 0,07806676 0,08736215 ! covalent chromatin modification GO:0016569 101 52 0,000 0,07806676 0,08732153 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,07806676 0,08728096 ! amino acid activation GO:0043038 92 52 0,000 0,07806676 0,08724042 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,07806676 0,08719992 ! synapse organization GO:0050808 85 52 0,000 0,07806676 0,08715945 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,079508 0,08872738 ! RNA catabolic process GO:0006401 93 53 0,000 0,079508 0,08868625 ! regulation of translational initiation GO:0006446 82 53 0,000 0,079508 0,08864515 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,079508 0,08860409 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,079508 0,08856307 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,079508 0,08852209 ! cell maturation GO:0048469 100 53 0,000 0,079508 0,08848115 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,079508 0,08844024 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,079508 0,08839937 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,08094703 0,08995776 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,08094703 0,08991623 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,08094703 0,08987474 ! cell recognition GO:0008037 85 54 0,000 0,08094703 0,08983328 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,08094703 0,08979187 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,08094703 0,08975049 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,08094703 0,08970915 ! chloride transport GO:0006821 90 55 0,000 0,08238386 0,09125947 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,08238386 0,09121748 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,08238386 0,09117552 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,08238386 0,0911336 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08238386 0,09109172 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,08238386 0,09104987 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08238386 0,09100807 ! aging GO:0007568 103 55 0,000 0,08238386 0,0909663 ! gastrulation GO:0007369 112 55 0,000 0,08238386 0,09092458 ! heart morphogenesis GO:0003007 97 55 0,000 0,08238386 0,09088289 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,08238386 0,09084124 ! nuclear export GO:0051168 97 55 0,000 0,08238386 0,09079962 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,08238386 0,09075805 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0838185 0,09229625 ! sensory perception of smell GO:0007608 80 56 0,000 0,0838185 0,09225403 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0838185 0,09221184 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0838185 0,0921697 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0838185 0,09212759 ! regulation of DNA replication GO:0006275 101 56 0,000 0,0838185 0,09208553 ! proton transport GO:0015992 94 56 0,000 0,0838185 0,0920435 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,0838185 0,09200151 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,08525094 0,09353112 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,08525094 0,09348849 ! muscle fiber development GO:0048747 112 57 0,000 0,08525094 0,0934459 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,08525094 0,09340335 ! lipid modification GO:0030258 97 57 0,000 0,08525094 0,09336083 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,08525094 0,09331836 ! hydrogen transport GO:0006818 97 58 0,000 0,08668118 0,0948408 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,08668118 0,09479769 ! regulation of endocytosis GO:0030100 91 58 0,000 0,08668118 0,09475462 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,08668118 0,09471159 ! positive regulation of secretion GO:0051047 95 59 0,000 0,08810924 0,09622825 ! regulation of cellular component size GO:0032535 109 59 0,000 0,08810924 0,09618459 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,08810924 0,09614097 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,08810924 0,09609738 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,08810924 0,09605384 ! DNA catabolic process GO:0006308 86 59 0,000 0,08810924 0,09601034 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,08810924 0,09596688 ! establishment of organelle localization GO:0051656 109 59 0,000 0,08810924 0,09592345 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,08953511 0,0974317 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,08953511 0,09738765 ! regulation of heart contraction GO:0008016 110 60 0,000 0,08953511 0,09734364 ! camera-type eye development GO:0043010 116 60 0,000 0,08953511 0,09729967 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,08953511 0,09725575 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,08953511 0,09721186 ! kidney development GO:0001822 122 60 0,000 0,08953511 0,09716801 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,0909588 0,09866856 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,0909588 0,0986241 ! mesoderm development GO:0007498 119 61 0,000 0,0909588 0,09857967 ! tRNA processing GO:0008033 89 61 0,000 0,0909588 0,09853529 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,0909588 0,09849094 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,0909588 0,09844664 ! ear development GO:0043583 103 62 0,000 0,09238031 0,09994021 ! viral reproductive process GO:0022415 126 62 0,000 0,09238031 0,0998953 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09238031 0,09985042 ! gonad development GO:0008406 98 62 0,000 0,09238031 0,09980558 ! regulation of mitosis GO:0007088 105 63 0,000 0,09379965 0,10129352 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,09379965 0,10124807 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,09379965 0,10120267 ! detection of external stimulus GO:0009581 91 63 0,000 0,09379965 0,10115731 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,09379965 0,10111199 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,09521681 0,10259366 ! cell redox homeostasis GO:0045454 102 64 0,000 0,09521681 0,10254774 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,09521681 0,10250186 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,09521681 0,10245601 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,09521681 0,10241021 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,09663181 0,10388567 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,09663181 0,10383927 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,09663181 0,10379291 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,09663181 0,1037466 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,09804463 0,1052165 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,09804463 0,10516959 ! developmental maturation GO:0021700 116 66 0,000 0,09804463 0,10512272 ! cell projection assembly GO:0030031 120 66 0,000 0,09804463 0,1050759 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,0994553 0,10654027 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,0994553 0,10649286 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,0994553 0,10644548 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,0994553 0,10639815 ! activation of MAPK activity GO:0000187 115 67 0,000 0,0994553 0,10635087 ! lung development GO:0030324 144 67 0,000 0,0994553 0,10630362 ! chromosome segregation GO:0007059 113 67 0,000 0,0994553 0,10625642 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,0994553 0,10620925 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,0994553 0,10616213 ! hexose catabolic process GO:0019320 104 67 0,000 0,0994553 0,10611505 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,0994553 0,10606802 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,0994553 0,10602102 ! activation of immune response GO:0002253 105 67 0,000 0,0994553 0,10597407 ! amino acid transport GO:0006865 125 68 0,000 0,1008638 0,10742732 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,1008638 0,10737978 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,1008638 0,10733229 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,1008638 0,10728484 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,1008638 0,10723743 ! regulation of lipase activity GO:0060191 130 68 0,000 0,1008638 0,10719007 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,1008638 0,10714274 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,1008638 0,10709546 ! negative regulation of cell size GO:0045792 134 69 0,000 0,10227015 0,1085408 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,10227015 0,10849294 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,10227015 0,10844513 ! urogenital system development GO:0001655 137 69 0,000 0,10227015 0,10839735 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,10227015 0,10834962 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,10227015 0,10830193 ! antigen processing and presentation GO:0019882 104 69 0,000 0,10227015 0,10825429 ! appendage morphogenesis GO:0035107 135 70 0,000 0,10367435 0,10969239 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,10367435 0,10964417 ! amine catabolic process GO:0009310 117 71 0,000 0,1050764 0,11107812 ! reproductive structure development GO:0048608 113 71 0,000 0,1050764 0,11102934 ! appendage development GO:0048736 136 71 0,000 0,1050764 0,1109806 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,1050764 0,11093191 ! regulation of immune effector process GO:0002697 137 71 0,000 0,1050764 0,11088325 ! acute inflammatory response GO:0002526 113 72 0,000 0,1064763 0,11231126 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,1064763 0,11226204 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,1064763 0,11221287 ! carbohydrate transport GO:0008643 110 72 0,000 0,1064763 0,11216374 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,1064763 0,11211465 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,1064763 0,1120656 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,1064763 0,1120166 ! respiratory system development GO:0060541 153 72 0,000 0,1064763 0,11196765 ! learning or memory GO:0007611 147 73 0,000 0,10787406 0,11338793 ! regulation of blood pressure GO:0008217 125 73 0,000 0,10787406 0,11333842 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,10787406 0,11328895 ! axon guidance GO:0007411 139 73 0,000 0,10787406 0,11323952 ! fertilization GO:0009566 90 73 0,000 0,10787406 0,11319013 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,10926967 0,11460455 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,10926967 0,11455461 ! neurotransmitter transport GO:0006836 123 74 0,000 0,10926967 0,11450472 ! meiosis GO:0007126 121 74 0,000 0,10926967 0,11445487 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,10926967 0,11440506 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,10926967 0,1143553 ! eye development GO:0001654 143 74 0,000 0,10926967 0,11430558 ! organelle localization GO:0051640 136 74 0,000 0,10926967 0,1142559 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,11066315 0,1156627 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,11066315 0,11561248 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,11066315 0,1155623 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,11066315 0,11551217 ! meiotic cell cycle GO:0051321 122 75 0,000 0,11066315 0,11546207 ! rhythmic process GO:0048511 128 75 0,000 0,11066315 0,11541203 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1120545 0,11681245 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1120545 0,11676186 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,1120545 0,11671131 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1120545 0,11666081 ! regulation of catabolic process GO:0009894 161 76 0,000 0,1120545 0,11661035 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,11344371 0,11800501 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,11344371 0,11795401 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,11344371 0,11790306 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,11344371 0,11785215 ! blood coagulation GO:0007596 146 78 0,000 0,1148308 0,11924165 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,1148308 0,11919021 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,1148308 0,11913882 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,11621577 0,12052377 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,11621577 0,12047184 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,11621577 0,12041996 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,11621577 0,12036812 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,11621577 0,12031632 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,11621577 0,12026458 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,11759861 0,12164328 ! response to metal ion GO:0010038 140 80 0,000 0,11759861 0,121591 ! muscle cell differentiation GO:0042692 159 80 0,000 0,11759861 0,12153877 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,11759861 0,12148659 ! inorganic anion transport GO:0015698 138 80 0,000 0,11759861 0,12143445 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,11897934 0,1228075 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,11897934 0,12275484 ! digestion GO:0007586 112 81 0,000 0,11897934 0,12270222 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,11897934 0,12264965 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,11897934 0,12259713 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,11897934 0,12254464 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,12035795 0,12391152 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,12035795 0,12385852 ! response to drug GO:0042493 143 82 0,000 0,12035795 0,12380557 ! response to nutrient GO:0007584 125 82 0,000 0,12035795 0,12375266 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,12035795 0,1236998 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,12035795 0,12364698 ! response to oxygen levels GO:0070482 176 83 0,000 0,12173445 0,12500772 ! regulation of lyase activity GO:0051339 160 83 0,000 0,12173445 0,12495439 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,12310884 0,12631125 ! hemostasis GO:0007599 158 84 0,000 0,12310884 0,1262574 ! negative regulation of transport GO:0051051 153 84 0,000 0,12310884 0,12620361 ! negative regulation of growth GO:0045926 155 84 0,000 0,12310884 0,12614986 ! regulation of ligase activity GO:0051340 142 84 0,000 0,12310884 0,12609616 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,12310884 0,1260425 ! response to unfolded protein GO:0006986 131 85 0,000 0,12448113 0,12739328 ! nucleosome assembly GO:0006334 122 85 0,000 0,12448113 0,12733911 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,12448113 0,12728499 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,12448113 0,12723092 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,12585131 0,12857675 ! response to inorganic substance GO:0010035 153 86 0,000 0,12585131 0,12852218 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,12585131 0,12846765 ! chromatin assembly GO:0031497 124 86 0,000 0,12585131 0,12841317 ! tube morphogenesis GO:0035239 176 86 0,000 0,12585131 0,12835874 ! mitochondrion organization GO:0007005 148 86 0,000 0,12585131 0,12830435 ! alcohol catabolic process GO:0046164 130 86 0,000 0,12585131 0,12825 ! amine transport GO:0015837 155 86 0,000 0,12585131 0,12819571 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,1272194 0,12953444 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,1272194 0,12947964 ! cellular respiration GO:0045333 135 88 0,000 0,12858539 0,13081456 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,12858539 0,13075928 ! gland development GO:0048732 206 88 0,000 0,12858539 0,13070403 ! cellular defense response GO:0006968 114 89 0,000 0,12994929 0,13203462 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,12994929 0,13197889 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,12994929 0,1319232 ! ossification GO:0001503 188 90 0,000 0,13131109 0,13324947 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,13131109 0,13319329 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,13131109 0,13313717 ! sex differentiation GO:0007548 145 90 0,000 0,13131109 0,13308108 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,13131109 0,13302505 ! bone development GO:0060348 189 91 0,000 0,13267082 0,13434595 ! sterol metabolic process GO:0016125 152 91 0,000 0,13267082 0,13428943 ! response to protein stimulus GO:0051789 149 91 0,000 0,13267082 0,13423296 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,13267082 0,13417654 ! regulation of defense response GO:0031347 149 92 0,000 0,13402846 0,13549263 ! nucleosome organization GO:0034728 138 92 0,000 0,13402846 0,13543573 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,13402846 0,13537887 ! vitamin metabolic process GO:0006766 139 92 0,000 0,13402846 0,13532206 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,13538402 0,13663336 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,13538402 0,13657608 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,13538402 0,13651884 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,13538402 0,13646164 ! regulation of membrane potential GO:0042391 164 93 0,000 0,13538402 0,1364045 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,13538402 0,1363474 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,1367375 0,13765289 ! female pregnancy GO:0007565 164 94 0,000 0,1367375 0,13759532 ! regulation of T cell activation GO:0050863 158 94 0,000 0,1367375 0,1375378 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,13808891 0,13883908 ! forebrain development GO:0030900 188 95 0,000 0,13808891 0,13878108 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,13808891 0,13872313 ! positive regulation of immune response GO:0050778 156 96 0,000 0,13943824 0,14002021 ! detection of stimulus GO:0051606 151 96 0,000 0,13943824 0,13996179 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,14078551 0,14125519 ! protein ubiquitination GO:0016567 217 97 0,000 0,14078551 0,14119631 ! hormone metabolic process GO:0042445 157 97 0,000 0,14078551 0,14113748 ! interphase GO:0051325 213 98 0,000 0,14213072 0,1424267 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,14213072 0,14236741 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,14347386 0,14365298 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,14347386 0,14359323 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,14347386 0,14353352 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,14481495 0,14481495