pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/809-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of axonogenesis GO:0050772 19 14 2,000 6,081E-06 0,01398732 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 1,604E-05 0,01844678 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 1,884E-05 0,0144414 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 3,32E-05 0,01908854 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 2,000 3,32E-05 0,01527083 ! regulation of cell morphogenesis GO:0022604 140 76 3,000 4,686E-05 0,01796274 ! cholesterol homeostasis GO:0042632 46 28 2,000 5,334E-05 0,0175253 GO:0055092|sterol homeostasis, ! regulation of axonogenesis GO:0050770 51 29 2,000 5,938E-05 0,01707253 ! cholesterol transport GO:0030301 46 30 2,000 6,586E-05 0,01683071 GO:0015918|sterol transport, ! positive regulation of neurogenesis GO:0050769 45 30 2,000 6,586E-05 0,01514764 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 1,000 6,739E-05 0,0140916 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 1,000 6,739E-05 0,0129173 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 6,739E-05 0,01192366 ! negative regulation of T cell mediated immunity GO:0002710 11 5 1,000 6,739E-05 0,01107197 GO:0002707|negative regulation of lymphocyte mediated immunity, ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 6,739E-05 0,01033384 ! positive regulation of cell development GO:0010720 54 33 2,000 8,802E-05 0,01265238 ! lipid homeostasis GO:0055088 55 33 2,000 8,802E-05 0,01190813 ! regulation of neuron projection development GO:0010975 63 34 2,000 9,636E-05 0,01231224 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 2,000 9,636E-05 0,01166422 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 1,000 1,009E-04 0,01160607 GO:0030816|positive regulation of cAMP metabolic process, ! male sex determination GO:0030238 9 6 1,000 1,009E-04 0,0110534 ! gas homeostasis GO:0033483 11 6 1,000 1,009E-04 0,01055097 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,009E-04 0,01009223 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 1,009E-04 9,672E-03 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 1,009E-04 9,285E-03 ! Rho protein signal transduction GO:0007266 51 35 2,000 1,052E-04 9,306E-03 ! protein homooligomerization GO:0051260 52 35 2,000 1,052E-04 8,961E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,411E-04 0,01158661 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 1,411E-04 0,01118707 ! vesicle fusion GO:0006906 15 7 1,000 1,411E-04 0,01081417 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 1,411E-04 0,01046532 ! lymph node development GO:0048535 9 7 1,000 1,411E-04 0,01013828 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 1,000 1,411E-04 9,831E-03 ! cell growth GO:0016049 61 39 2,000 1,458E-04 9,864E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 1,458E-04 9,582E-03 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 1,000 1,878E-04 0,01199559 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 1,878E-04 0,01167139 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,878E-04 0,01136425 ! regulation of smoothened signaling pathway GO:0008589 13 8 1,000 1,878E-04 0,01107286 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 1,878E-04 0,01079603 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,878E-04 0,01053272 ! induction of an organ GO:0001759 11 8 1,000 1,878E-04 0,01028194 ! intracellular lipid transport GO:0032365 13 8 1,000 1,878E-04 0,01004282 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 1,878E-04 9,815E-03 ! vesicle organization GO:0016050 79 43 2,000 1,955E-04 9,99E-03 ! regulation of cell projection organization GO:0031344 83 44 2,000 2,094E-04 0,01046842 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 2,41E-04 0,01179349 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 1,000 2,41E-04 0,01154779 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of protein polymerization GO:0032273 15 9 1,000 2,41E-04 0,01131212 ! localization within membrane GO:0051668 15 9 1,000 2,41E-04 0,01108588 ! phospholipid efflux GO:0033700 16 10 1,000 3,007E-04 0,01356286 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 3,007E-04 0,01330204 ! reverse cholesterol transport GO:0043691 16 10 1,000 3,007E-04 0,01305105 ! phagocytosis, engulfment GO:0006911 20 10 1,000 3,007E-04 0,01280937 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 3,007E-04 0,01257647 ! embryonic gut development GO:0048566 11 10 1,000 3,007E-04 0,01235189 ! developmental induction GO:0031128 13 10 1,000 3,007E-04 0,01213519 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of immune effector process GO:0002698 16 10 1,000 3,007E-04 0,01192596 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,67E-04 0,01430511 ! chondrocyte differentiation GO:0002062 17 11 1,000 3,67E-04 0,01406669 ! cholesterol efflux GO:0033344 19 11 1,000 3,67E-04 0,01383609 ! gland morphogenesis GO:0022612 23 12 1,000 4,396E-04 0,01630814 ! lung development GO:0030324 94 59 2,000 4,999E-04 0,01825148 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 5,187E-04 0,01863969 ! lipid localization GO:0010876 24 13 1,000 5,187E-04 0,01835293 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 5,187E-04 0,01807485 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 5,187E-04 0,01780508 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 5,187E-04 0,01754324 ! embryonic limb morphogenesis GO:0030326 86 60 2,000 5,253E-04 0,01750925 GO:0035113|embryonic appendage morphogenesis, ! respiratory tube development GO:0030323 99 62 2,000 5,784E-04 0,0190048 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 6,041E-04 0,01956947 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 6,041E-04 0,01929767 ! appendage morphogenesis GO:0035107 93 64 2,000 6,349E-04 0,02000237 GO:0035108|limb morphogenesis, ! respiratory system development GO:0060541 100 64 2,000 6,349E-04 0,01973207 ! appendage development GO:0048736 94 65 2,000 6,644E-04 0,02037354 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 101 65 2,000 6,644E-04 0,02010547 ! protein oligomerization GO:0051259 100 65 2,000 6,644E-04 0,01984436 ! lipid phosphorylation GO:0046834 23 15 1,000 6,959E-04 0,02051931 ! peptide secretion GO:0002790 27 15 1,000 6,959E-04 0,02025957 ! embryonic digit morphogenesis GO:0042733 18 15 1,000 6,959E-04 0,02000633 ! regulation of vasodilation GO:0042312 24 15 1,000 6,959E-04 0,01975934 ! regulation of T cell mediated immunity GO:0002709 26 15 1,000 6,959E-04 0,01951837 ! regulation of neuron differentiation GO:0045664 107 67 2,000 7,259E-04 0,02011647 ! protein secretion GO:0009306 27 16 1,000 7,94E-04 0,02173913 ! negative regulation of immune response GO:0050777 28 16 1,000 7,94E-04 0,02148338 ! regulation of peptidase activity GO:0052547 106 72 2,000 8,955E-04 0,02394965 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 8,983E-04 0,02374828 ! inactivation of MAPK activity GO:0000188 27 17 1,000 8,983E-04 0,02347842 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 8,983E-04 0,02321461 ! neuromuscular junction development GO:0007528 23 17 1,000 8,983E-04 0,02295667 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 9,698E-04 0,0245109 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 1,009E-03 0,02522253 ! gut development GO:0048565 26 18 1,000 1,009E-03 0,02495132 ! sex determination GO:0007530 29 19 1,000 1,126E-03 0,02754392 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 1,126E-03 0,02725399 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 1,126E-03 0,02697009 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 1,126E-03 0,02669205 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 1,249E-03 0,02930608 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 1,000 1,249E-03 0,02901006 ! ossification GO:0001503 134 82 2,000 1,306E-03 0,03002787 GO:0060348|bone development, ! regulation of cell killing GO:0031341 34 21 1,000 1,378E-03 0,03137624 ! vesicle docking GO:0048278 27 21 1,000 1,378E-03 0,03106863 ! regulation of DNA recombination GO:0000018 40 21 1,000 1,378E-03 0,030767 ! regulation of vasoconstriction GO:0019229 31 21 1,000 1,378E-03 0,03047116 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 1,378E-03 0,03018096 ! vasculogenesis GO:0001570 33 22 1,000 1,513E-03 0,03283085 ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 1,513E-03 0,03252402 ! lysosome organization GO:0007040 37 22 1,000 1,513E-03 0,03222287 ! membrane depolarization GO:0051899 35 22 1,000 1,513E-03 0,03192725 ! regulation of blood coagulation GO:0030193 34 22 1,000 1,513E-03 0,031637 ! skeletal muscle tissue development GO:0007519 123 87 2,000 1,548E-03 0,03208229 GO:0060538|skeletal muscle organ development, ! regulation of neurogenesis GO:0050767 153 89 2,000 1,653E-03 0,03394161 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 1,654E-03 0,03367372 ! osteoblast differentiation GO:0001649 40 23 1,000 1,654E-03 0,03337834 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 1,802E-03 0,03603574 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 1,802E-03 0,03572509 ! vacuole organization GO:0007033 39 24 1,000 1,802E-03 0,03541974 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 1,802E-03 0,03511958 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 1,955E-03 0,03778938 ! peptide transport GO:0015833 43 25 1,000 1,955E-03 0,03747447 ! male gonad development GO:0008584 33 25 1,000 1,955E-03 0,03716476 ! phospholipid transport GO:0015914 35 25 1,000 1,955E-03 0,03686014 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 1,955E-03 0,03656046 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 2,115E-03 0,03922208 ! regulation of coagulation GO:0050818 39 26 1,000 2,115E-03 0,0389083 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 2,115E-03 0,03859951 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 2,115E-03 0,03829557 ! calcium ion transport GO:0006816 167 99 2,000 2,241E-03 0,04027354 ! membrane docking GO:0022406 39 27 1,000 2,28E-03 0,04064994 ! inner ear morphogenesis GO:0042472 35 27 1,000 2,28E-03 0,04033725 ! divalent metal ion transport GO:0070838 171 100 2,000 2,306E-03 0,04049403 ! Ras protein signal transduction GO:0007265 162 100 2,000 2,306E-03 0,04018725 ! triglyceride metabolic process GO:0006641 34 28 1,000 2,451E-03 0,04238931 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 2,451E-03 0,04207297 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 2,451E-03 0,04176132 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 2,628E-03 0,04445054 ! regulation of microtubule-based process GO:0032886 58 30 1,000 2,811E-03 0,04719897 ! mammary gland development GO:0030879 57 31 1,000 3E-03 0,05000481 ! cell fate specification GO:0001708 37 31 1,000 3E-03 0,04964506 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 3,195E-03 0,05248869 ! neutral lipid metabolic process GO:0006638 41 32 1,000 3,195E-03 0,05211643 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 1,000 3,195E-03 0,05174941 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 3,195E-03 0,05138753 ! cytokine production GO:0001816 44 32 1,000 3,195E-03 0,05103067 ! ear morphogenesis GO:0042471 42 33 1,000 3,395E-03 0,05385826 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 3,602E-03 0,05673758 ! glycerol ether metabolic process GO:0006662 44 34 1,000 3,602E-03 0,05635161 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 3,602E-03 0,05597085 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 3,602E-03 0,05559521 ! embryonic organ development GO:0048568 45 34 1,000 3,602E-03 0,05522457 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 3,814E-03 0,05808652 ! organic ether metabolic process GO:0018904 46 36 1,000 4,031E-03 0,06099678 ! tissue remodeling GO:0048771 62 36 1,000 4,031E-03 0,06059811 ! hormone-mediated signaling GO:0009755 49 36 1,000 4,031E-03 0,06020462 ! amino acid activation GO:0043038 52 37 1,000 4,254E-03 0,06312877 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! phagocytosis GO:0006909 60 38 1,000 4,483E-03 0,06609832 ! male sex differentiation GO:0046661 53 39 1,000 4,718E-03 0,06911197 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 1,000 4,718E-03 0,06867455 ! synapse organization GO:0050808 55 39 1,000 4,718E-03 0,06824264 ! inner ear development GO:0048839 57 40 1,000 4,958E-03 0,07126635 ! T cell differentiation GO:0030217 65 40 1,000 4,958E-03 0,0708237 ! positive regulation of protein transport GO:0051222 55 40 1,000 4,958E-03 0,07038652 ! protein amino acid lipidation GO:0006497 62 41 1,000 5,203E-03 0,0734195 ! endosome transport GO:0016197 71 41 1,000 5,203E-03 0,07297182 ! regulation of leukocyte mediated immunity GO:0002703 62 41 1,000 5,203E-03 0,07252957 ! regulation of T cell differentiation GO:0045580 59 41 1,000 5,203E-03 0,07209264 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 5,454E-03 0,07511856 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 5,454E-03 0,07467143 ! embryonic skeletal system development GO:0048706 56 42 1,000 5,454E-03 0,07422959 ! regulation of cell shape GO:0008360 78 42 1,000 5,454E-03 0,07379294 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 1,000 5,711E-03 0,07681177 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 5,711E-03 0,07636519 ! response to insulin stimulus GO:0032868 63 43 1,000 5,711E-03 0,07592377 ! positive regulation of cell cycle GO:0045787 77 45 1,000 6,24E-03 0,08248473 ! lipoprotein biosynthetic process GO:0042158 67 45 1,000 6,24E-03 0,08201339 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 6,24E-03 0,0815474 ! regulation of adaptive immune response GO:0002819 72 46 1,000 6,513E-03 0,08463122 ! response to UV GO:0009411 75 46 1,000 6,513E-03 0,08415576 ! negative regulation of immune system process GO:0002683 73 47 1,000 6,791E-03 0,0872594 ! regulation of protein polymerization GO:0032271 71 47 1,000 6,791E-03 0,08677463 ! regulation of muscle contraction GO:0006937 69 48 1,000 7,075E-03 0,08989722 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 7,075E-03 0,08940328 ! regulation of intracellular transport GO:0032386 78 49 1,000 7,363E-03 0,092544 ! cartilage development GO:0051216 70 49 1,000 7,363E-03 0,09204104 ! ear development GO:0043583 72 50 1,000 7,657E-03 0,09519909 ! skeletal muscle fiber development GO:0048741 73 50 1,000 7,657E-03 0,09468727 ! membrane fusion GO:0006944 80 50 1,000 7,657E-03 0,09418092 ! lipid modification GO:0030258 73 50 1,000 7,657E-03 0,09367996 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 7,957E-03 0,09682631 ! activation of phospholipase C activity GO:0007202 87 51 1,000 7,957E-03 0,09631669 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 7,957E-03 0,09581242 ! positive regulation of cell migration GO:0030335 92 51 1,000 7,957E-03 0,09531339 ! positive regulation of organelle organization GO:0010638 82 51 1,000 7,957E-03 0,09481954 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 8,261E-03 0,09794076 ! regulation of protein complex assembly GO:0043254 81 54 1,000 8,886E-03 0,10480461 ! regulation of phospholipase activity GO:0010517 90 54 1,000 8,886E-03 0,1042699 ! positive regulation of lipase activity GO:0060193 90 54 1,000 8,886E-03 0,10374061 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 9,531E-03 0,11070956 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 9,531E-03 0,11015323 ! positive regulation of cell motion GO:0051272 99 56 1,000 9,531E-03 0,10960247 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 9,861E-03 0,11283497 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 9,861E-03 0,11227638 ! gonad development GO:0008406 79 57 1,000 9,861E-03 0,1117233 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,01019599 0,11495478 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,01088141 0,12208406 ! lipoprotein metabolic process GO:0042157 89 61 1,000 0,01123157 0,12540107 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,01123157 0,12479527 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,01123157 0,12419529 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,0119467 0,13147081 ! regulation of lipase activity GO:0060191 109 63 1,000 0,0119467 0,13084476 ! reproductive structure development GO:0048608 90 65 1,000 0,01268135 0,13823269 ! regulation of caspase activity GO:0043281 97 65 1,000 0,01268135 0,13758065 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,01268135 0,13693473 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,01305593 0,14032073 ! regulation of immune effector process GO:0002697 101 66 1,000 0,01305593 0,13966808 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01308882 0,13937174 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01308882 0,13872948 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01308882 0,13809311 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01308882 0,13746254 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01308882 0,13683771 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01308882 0,13621854 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01308882 0,13560494 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01308882 0,13499685 ! sleep GO:0030431 11 5 0,000 0,01308882 0,13439418 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01308882 0,13379688 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01308882 0,13320485 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01308882 0,13261805 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01308882 0,13203639 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01308882 0,13145981 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01308882 0,13088825 ! tongue development GO:0043586 6 5 0,000 0,01308882 0,13032163 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01308882 0,1297599 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01308882 0,12920299 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01308882 0,12865084 ! cobalt ion transport GO:0006824 9 5 0,000 0,01308882 0,12810339 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01308882 0,12756058 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01308882 0,12702235 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01308882 0,12648864 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01308882 0,1259594 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01308882 0,12543457 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01308882 0,1249141 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01308882 0,12439792 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01308882 0,123886 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01308882 0,12337827 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01308882 0,12287468 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01308882 0,12237519 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01308882 0,12187974 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01308882 0,12138829 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01308882 0,12090079 ! malate metabolic process GO:0006108 7 5 0,000 0,01308882 0,12041719 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01308882 0,11993744 ! behavioral response to pain GO:0048266 7 5 0,000 0,01308882 0,1194615 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01308882 0,11898932 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01308882 0,11852085 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01308882 0,11805607 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01308882 0,11759491 ! mating behavior GO:0007617 6 5 0,000 0,01308882 0,11713734 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01308882 0,11668332 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01308882 0,11623281 ! rhythmic behavior GO:0007622 12 5 0,000 0,01308882 0,11578576 ! copulation GO:0007620 7 5 0,000 0,01308882 0,11534213 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01308882 0,1149019 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01308882 0,11446501 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01308882 0,11403143 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01308882 0,11360112 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01308882 0,11317405 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01308882 0,11275018 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01308882 0,11232947 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01308882 0,11191188 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01308882 0,1114974 ! response to protozoan GO:0001562 9 5 0,000 0,01308882 0,11108597 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01308882 0,11067756 ! lymph vessel development GO:0001945 7 5 0,000 0,01308882 0,11027215 ! endochondral ossification GO:0001958 12 5 0,000 0,01308882 0,1098697 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01308882 0,10947017 ! parathyroid gland development GO:0060017 8 5 0,000 0,01308882 0,10907354 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01308882 0,10867977 ! anagen GO:0042640 6 5 0,000 0,01308882 0,10828884 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01308882 0,10790071 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01308882 0,10751535 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01308882 0,10713273 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01308882 0,10675283 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01308882 0,10637561 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01308882 0,10600105 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01308882 0,10562911 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01308882 0,10525978 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01308882 0,10489302 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01308882 0,10452881 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01308882 0,10416712 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01308882 0,10380792 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01308882 0,10345119 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01308882 0,10309691 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01308882 0,10274504 ! ovulation GO:0030728 6 5 0,000 0,01308882 0,10239557 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01308882 0,10204846 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01308882 0,10170371 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01308882 0,10136127 ! response to pH GO:0009268 9 5 0,000 0,01308882 0,10102113 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01308882 0,10068327 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01308882 0,10034766 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01308882 0,10001428 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01308882 0,0996831 ! polyol catabolic process GO:0046174 7 5 0,000 0,01308882 0,09935412 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01308882 0,09902729 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01308882 0,09870261 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01308882 0,09838006 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01308882 0,0980596 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01308882 0,09774122 ! urea metabolic process GO:0019627 6 5 0,000 0,01308882 0,09742491 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01308882 0,09711064 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01308882 0,09679838 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01308882 0,09648813 ! neutrophil activation GO:0042119 5 5 0,000 0,01308882 0,09617986 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01308882 0,09587356 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01308882 0,0955692 ! response to food GO:0032094 5 5 0,000 0,01308882 0,09526676 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01308882 0,09496624 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01308882 0,0946676 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01308882 0,09437084 ! forebrain neuron development GO:0021884 7 5 0,000 0,01308882 0,09407593 ! melanosome organization GO:0032438 7 5 0,000 0,01308882 0,09378286 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01308882 0,09349161 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01308882 0,09320216 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01308882 0,0929145 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01308882 0,09262861 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01308882 0,09234447 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01308882 0,09206207 ! nucleoside transport GO:0015858 6 5 0,000 0,01308882 0,09178139 ! nucleoside salvage GO:0043174 7 5 0,000 0,01308882 0,09150242 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01308882 0,09122514 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01308882 0,09094954 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01308882 0,09067559 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01308882 0,09040329 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01308882 0,09013263 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01308882 0,08986357 ! depyrimidination GO:0045008 8 5 0,000 0,01308882 0,08959612 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01308882 0,08933026 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01308882 0,08906597 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01308882 0,08880324 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01308882 0,08854205 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01308882 0,0882824 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01308882 0,08802426 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01308882 0,08776763 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01308882 0,08751249 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01308882 0,08725883 ! monocyte differentiation GO:0030224 8 5 0,000 0,01308882 0,08700664 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01308882 0,0867559 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01308882 0,0865066 ! centrosome duplication GO:0051298 5 5 0,000 0,01308882 0,08625873 ! response to UV-C GO:0010225 6 5 0,000 0,01308882 0,08601228 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01308882 0,08576723 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01308882 0,08552357 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01308882 0,08528129 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01308882 0,08504039 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01308882 0,08480084 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01308882 0,08456263 ! melanosome transport GO:0032402 8 5 0,000 0,01308882 0,08432576 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01308882 0,08409021 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01308882 0,08385598 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01308882 0,08362305 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01308882 0,0833914 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01308882 0,08316104 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01308882 0,08293195 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01308882 0,08270411 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01308882 0,08247753 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01308882 0,08225218 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01308882 0,08202806 ! neural tube patterning GO:0021532 6 5 0,000 0,01308882 0,08180515 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01308882 0,08158346 ! histone demethylation GO:0016577 9 5 0,000 0,01308882 0,08136296 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01308882 0,08114366 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01308882 0,08092553 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01308882 0,08070857 ! enteric nervous system development GO:0048484 8 5 0,000 0,01308882 0,08049277 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01308882 0,08027813 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01308882 0,08006462 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01308882 0,07985225 ! transcription termination GO:0006353 8 5 0,000 0,01308882 0,079641 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01308882 0,07943086 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01308882 0,07922183 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01308882 0,0790139 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01308882 0,07880706 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01308882 0,0786013 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01308882 0,07839661 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01308882 0,07819298 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01308882 0,07799041 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01308882 0,07778888 ! apical protein localization GO:0045176 6 5 0,000 0,01308882 0,07758839 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01308882 0,07738894 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01308882 0,0771905 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01308882 0,07699309 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01308882 0,07679668 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01308882 0,07660126 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01308882 0,07640684 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01308882 0,07621341 ! glial cell migration GO:0008347 10 5 0,000 0,01308882 0,07602095 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01308882 0,07582946 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01308882 0,07563894 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01308882 0,07544937 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01308882 0,07526074 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01308882 0,07507306 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01308882 0,07488631 ! neural plate development GO:0001840 6 5 0,000 0,01308882 0,07470049 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01308882 0,07451559 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01308882 0,0743316 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01308882 0,07414851 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01308882 0,07396633 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01308882 0,07378504 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01308882 0,07360464 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01308882 0,07342511 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01308882 0,07324646 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01308882 0,07306868 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01308882 0,07289176 ! spindle assembly GO:0051225 5 5 0,000 0,01308882 0,07271569 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01308882 0,07254047 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01308882 0,0723661 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01308882 0,07219256 ! organ regeneration GO:0031100 7 5 0,000 0,01308882 0,07201985 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01308882 0,07184796 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01308882 0,0716769 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01308882 0,07150664 GO:0055081|anion homeostasis, ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,01343531 0,07322564 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,01381947 0,07514134 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,01381947 0,07496412 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,01460201 0,07902265 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,01500034 0,08098773 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,01540333 0,08296876 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,01540333 0,08277491 ! tRNA transcription GO:0009304 11 6 0,000 0,01568641 0,08409961 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01568641 0,08390403 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01568641 0,08370936 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01568641 0,08351558 ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01568641 0,08332271 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01568641 0,08313072 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01568641 0,08293961 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01568641 0,08274939 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01568641 0,08256003 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01568641 0,08237153 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01568641 0,0821839 ! prostate gland development GO:0030850 9 6 0,000 0,01568641 0,08199712 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01568641 0,08181118 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01568641 0,08162609 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01568641 0,08144183 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01568641 0,08125841 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01568641 0,0810758 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01568641 0,08089402 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01568641 0,08071305 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01568641 0,08053288 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01568641 0,08035352 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01568641 0,08017496 ! neuron adhesion GO:0007158 9 6 0,000 0,01568641 0,07999719 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01568641 0,0798202 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01568641 0,079644 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01568641 0,07946857 ! signal peptide processing GO:0006465 8 6 0,000 0,01568641 0,07929392 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01568641 0,07912003 ! mRNA stabilization GO:0048255 15 6 0,000 0,01568641 0,0789469 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01568641 0,07877452 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01568641 0,0786029 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01568641 0,07843203 ! opsonization GO:0008228 8 6 0,000 0,01568641 0,07826189 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01568641 0,07809249 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01568641 0,07792383 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01568641 0,07775589 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01568641 0,07758867 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01568641 0,07742217 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01568641 0,07725639 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01568641 0,07709131 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01568641 0,07692693 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01568641 0,07676326 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01568641 0,07660028 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01568641 0,07643799 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01568641 0,07627639 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01568641 0,07611547 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01568641 0,07595523 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01568641 0,07579566 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01568641 0,07563675 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01568641 0,07547852 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01568641 0,07532094 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01568641 0,07516403 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01568641 0,07500776 ! thymic T cell selection GO:0045061 12 6 0,000 0,01568641 0,07485214 ! protein lipoylation GO:0009249 10 6 0,000 0,01568641 0,07469717 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01568641 0,07454283 ! pigment granule organization GO:0048753 11 6 0,000 0,01568641 0,07438914 ! drug transport GO:0015893 6 6 0,000 0,01568641 0,07423607 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01568641 0,07408364 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01568641 0,07393183 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01568641 0,07378064 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01568641 0,07363007 ! histidine metabolic process GO:0006547 6 6 0,000 0,01568641 0,07348011 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01568641 0,07333076 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01568641 0,07318201 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01568641 0,07303387 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01568641 0,07288633 ! adenohypophysis development GO:0021984 10 6 0,000 0,01568641 0,07273938 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01568641 0,07259302 ! hyperosmotic response GO:0006972 8 6 0,000 0,01568641 0,07244725 ! microtubule nucleation GO:0007020 10 6 0,000 0,01568641 0,07230207 ! ER overload response GO:0006983 7 6 0,000 0,01568641 0,07215746 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01568641 0,07201344 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01568641 0,07186998 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01568641 0,0717271 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01568641 0,07158479 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01568641 0,07144303 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01568641 0,07130184 ! response to dietary excess GO:0002021 7 6 0,000 0,01568641 0,07116121 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01568641 0,07102113 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01568641 0,0708816 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01568641 0,07074261 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01568641 0,07060417 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01568641 0,07046627 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01568641 0,07032891 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01568641 0,07019209 ! neuron apoptosis GO:0051402 8 6 0,000 0,01568641 0,07005579 ! organic alcohol transport GO:0015850 9 6 0,000 0,01568641 0,06992002 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01568641 0,06978478 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01568641 0,06965006 ! carnitine transport GO:0015879 8 6 0,000 0,01568641 0,06951586 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01568641 0,06938218 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01568641 0,06924901 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01568641 0,06911634 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01568641 0,06898419 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01568641 0,06885254 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01568641 0,06872139 ! parturition GO:0007567 12 6 0,000 0,01568641 0,06859075 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01568641 0,06846059 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01568641 0,06833093 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01568641 0,06820176 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01568641 0,06807308 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01568641 0,06794488 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01568641 0,06781717 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01568641 0,06768993 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01568641 0,06756317 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01568641 0,06743688 ! macrophage differentiation GO:0030225 10 6 0,000 0,01568641 0,06731107 ! astrocyte development GO:0014002 14 6 0,000 0,01568641 0,06718572 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01568641 0,06706084 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01568641 0,06693642 ! interaction with symbiont GO:0051702 8 6 0,000 0,01568641 0,06681247 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01568641 0,06668897 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01568641 0,06656593 ! eating behavior GO:0042755 6 6 0,000 0,01568641 0,06644334 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01568641 0,0663212 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01568641 0,06619951 ! response to copper ion GO:0046688 9 6 0,000 0,01568641 0,06607826 ! DNA topological change GO:0006265 8 6 0,000 0,01568641 0,06595746 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01568641 0,0658371 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01568641 0,06571718 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01568641 0,06559769 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01568641 0,06547864 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01568641 0,06536002 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01568641 0,06524183 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01568641 0,06512407 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01568641 0,06500672 ! hair follicle maturation GO:0048820 7 6 0,000 0,01568641 0,06488981 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01568641 0,06477331 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01568641 0,06465723 ! Schwann cell development GO:0014044 14 6 0,000 0,01568641 0,06454156 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01568641 0,06442631 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01568641 0,06431147 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01568641 0,06419703 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01568641 0,06408301 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01568641 0,06396938 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01568641 0,06385616 ! histone ubiquitination GO:0016574 7 6 0,000 0,01568641 0,06374334 ! regulation of meiosis GO:0040020 10 6 0,000 0,01568641 0,06363092 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01568641 0,06351889 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01568641 0,06340726 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01568641 0,06329602 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01568641 0,06318517 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01568641 0,06307471 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01568641 0,06296463 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01568641 0,06285493 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01568641 0,06274562 ! receptor internalization GO:0031623 9 6 0,000 0,01568641 0,06263669 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01568641 0,06252813 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01568641 0,06241995 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01568641 0,06231215 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01568641 0,06220471 ! protein deubiquitination GO:0016579 8 6 0,000 0,01568641 0,06209765 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01568641 0,06199095 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01568641 0,06188462 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01568641 0,06177865 ! axonal fasciculation GO:0007413 9 6 0,000 0,01568641 0,06167305 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01568641 0,0615678 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01568641 0,06146292 ! midbrain development GO:0030901 6 6 0,000 0,01568641 0,06135839 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01568641 0,06125421 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01568641 0,06115039 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01568641 0,06104692 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01568641 0,0609438 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01568641 0,06084103 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01568641 0,06073861 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01568641 0,06063652 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01568641 0,06053479 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01568641 0,06043339 ! adult feeding behavior GO:0008343 6 6 0,000 0,01568641 0,06033233 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01568641 0,06023161 ! blastocyst growth GO:0001832 15 6 0,000 0,01568641 0,06013122 ! pigment granule transport GO:0051904 12 6 0,000 0,01568641 0,06003117 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01568641 0,05993145 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01568641 0,05983206 ! catecholamine transport GO:0051937 7 6 0,000 0,01568641 0,059733 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01568641 0,05963427 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01568641 0,05953586 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01568641 0,05943778 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01568641 0,05934002 ! protein prenylation GO:0018342 10 6 0,000 0,01568641 0,05924258 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01568641 0,05914546 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01568641 0,05904866 ! response to oxygen levels GO:0070482 137 74 1,000 0,01622322 0,06096964 ! protein import into nucleus GO:0006606 118 74 1,000 0,01622322 0,06087017 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,01622322 0,06077104 ! blood coagulation GO:0007596 116 75 1,000 0,01664007 0,06223116 GO:0050817|coagulation, ! nuclear import GO:0051170 121 75 1,000 0,01664007 0,06213014 ! tRNA metabolic process GO:0006399 95 76 1,000 0,01706148 0,06360034 ! regulation of protein transport GO:0051223 114 76 1,000 0,01706148 0,06349743 GO:0070201|regulation of establishment of protein localization, ! cholesterol metabolic process GO:0008203 109 77 1,000 0,01748743 0,06497754 ! gland development GO:0048732 148 77 1,000 0,01748743 0,06487274 ! sex differentiation GO:0007548 105 77 1,000 0,01748743 0,06476827 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0182773 0,06758486 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0182773 0,06747638 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0182773 0,06736824 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0182773 0,06726045 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0182773 0,06715301 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0182773 0,06704591 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0182773 0,06693915 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0182773 0,06683272 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0182773 0,06672664 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0182773 0,06662089 ! reproductive behavior GO:0019098 12 7 0,000 0,0182773 0,06651548 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0182773 0,0664104 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0182773 0,06630565 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0182773 0,06620123 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0182773 0,06609714 ! oligopeptide transport GO:0006857 11 7 0,000 0,0182773 0,06599338 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0182773 0,06588994 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0182773 0,06578683 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,0182773 0,06568404 ! pericardium development GO:0060039 8 7 0,000 0,0182773 0,06558157 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0182773 0,06547941 ! fibril organization GO:0043206 13 7 0,000 0,0182773 0,06537758 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0182773 0,06527606 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0182773 0,06517486 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0182773 0,06507397 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0182773 0,06497339 ! lipoprotein transport GO:0042953 9 7 0,000 0,0182773 0,06487312 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0182773 0,06477316 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0182773 0,06467351 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0182773 0,06457417 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0182773 0,06447513 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0182773 0,06437639 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0182773 0,06427796 ! chemosensory behavior GO:0007635 9 7 0,000 0,0182773 0,06417982 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0182773 0,06408199 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0182773 0,06398445 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0182773 0,06388721 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0182773 0,06379026 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0182773 0,06369361 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0182773 0,06359725 ! reflex GO:0060004 12 7 0,000 0,0182773 0,06350118 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0182773 0,0634054 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0182773 0,06330991 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0182773 0,06321471 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0182773 0,06311979 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0182773 0,06302516 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0182773 0,06293081 ! spinal cord patterning GO:0021511 7 7 0,000 0,0182773 0,06283675 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0182773 0,06274296 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0182773 0,06264945 ! adrenal gland development GO:0030325 17 7 0,000 0,0182773 0,06255622 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0182773 0,06246327 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0182773 0,0623706 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0182773 0,0622782 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0182773 0,06218607 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0182773 0,06209421 ! endosome organization GO:0007032 10 7 0,000 0,0182773 0,06200263 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0182773 0,06191132 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0182773 0,06182027 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0182773 0,06172949 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0182773 0,06163898 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0182773 0,06154873 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0182773 0,06145875 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0182773 0,06136903 ! galactose metabolic process GO:0006012 10 7 0,000 0,0182773 0,06127957 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0182773 0,06119037 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0182773 0,06110143 ! organ growth GO:0035265 11 7 0,000 0,0182773 0,06101275 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0182773 0,06092432 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0182773 0,06083616 ! retinol metabolic process GO:0042572 9 7 0,000 0,0182773 0,06074824 ! behavioral fear response GO:0001662 13 7 0,000 0,0182773 0,06066058 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0182773 0,06057317 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0182773 0,06048602 ! rRNA modification GO:0000154 12 7 0,000 0,0182773 0,06039911 ! protein heterooligomerization GO:0051291 10 7 0,000 0,0182773 0,06031246 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0182773 0,06022605 ! response to UV-B GO:0010224 11 7 0,000 0,0182773 0,06013989 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0182773 0,06005398 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0182773 0,05996831 ! intermediate filament organization GO:0045109 11 7 0,000 0,0182773 0,05988288 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0182773 0,0597977 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0182773 0,05971276 ! fibrinolysis GO:0042730 9 7 0,000 0,0182773 0,05962806 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,0182773 0,0595436 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0182773 0,05945938 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0182773 0,0593754 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0182773 0,05929165 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0182773 0,05920815 ! response to tropane GO:0014073 13 7 0,000 0,0182773 0,05912487 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0182773 0,05904183 ! melanosome localization GO:0032400 10 7 0,000 0,0182773 0,05895902 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0182773 0,05887645 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0182773 0,0587941 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0182773 0,05871199 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0182773 0,0586301 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0182773 0,05854844 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0182773 0,05846701 ! mast cell activation GO:0045576 9 7 0,000 0,0182773 0,05838581 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0182773 0,05830483 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0182773 0,05822408 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0182773 0,05814355 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0182773 0,05806324 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0182773 0,05798315 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0182773 0,05790328 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0182773 0,05782364 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0182773 0,05774421 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0182773 0,057665 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0182773 0,057586 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0182773 0,05750723 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0182773 0,05742867 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0182773 0,05735032 ! response to tumor cell GO:0002347 12 7 0,000 0,0182773 0,05727218 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0182773 0,05719426 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0182773 0,05711655 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0182773 0,05703905 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0182773 0,05696177 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0182773 0,05688469 ! diuresis GO:0030146 12 7 0,000 0,0182773 0,05680782 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0182773 0,05673115 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0182773 0,05665469 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0182773 0,05657844 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0182773 0,0565024 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0182773 0,05642655 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0182773 0,05635092 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0182773 0,05627548 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0182773 0,05620024 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0182773 0,05612521 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0182773 0,05605038 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0182773 0,05597574 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0182773 0,05590131 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0182773 0,05582707 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0182773 0,05575303 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0182773 0,05567918 ! ATP catabolic process GO:0006200 10 7 0,000 0,0182773 0,05560553 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0182773 0,05553208 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0182773 0,05545882 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0182773 0,05538575 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0182773 0,05531287 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0182773 0,05524019 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0182773 0,05516769 ! muscle adaptation GO:0043500 12 7 0,000 0,0182773 0,05509539 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0182773 0,05502328 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0182773 0,05495135 ! retina homeostasis GO:0001895 9 7 0,000 0,0182773 0,05487961 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0182773 0,05480806 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0182773 0,0547367 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0182773 0,05466552 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0182773 0,05459452 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0182773 0,05452371 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0182773 0,05445309 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0182773 0,05438264 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,01835285 0,05453689 ! T cell activation GO:0042110 134 79 1,000 0,01835285 0,05446652 ! protein localization in nucleus GO:0034504 133 80 1,000 0,01879227 0,05569872 ! regulation of GTPase activity GO:0043087 129 80 1,000 0,01879227 0,05562704 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,01923612 0,0568677 ! hemostasis GO:0007599 125 81 1,000 0,01923612 0,0567947 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01923612 0,05672189 GO:0002696|positive regulation of leukocyte activation, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,02013703 0,0593024 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! sterol metabolic process GO:0016125 120 84 1,000 0,02059404 0,06057072 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02086152 0,06127904 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02086152 0,06120088 ! axon extension GO:0048675 11 8 0,000 0,02086152 0,06112292 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02086152 0,06104515 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02086152 0,06096758 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02086152 0,06089021 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02086152 0,06081304 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02086152 0,06073606 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02086152 0,06065928 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02086152 0,06058269 ! phosphate transport GO:0006817 10 8 0,000 0,02086152 0,06050629 ! N-glycan processing GO:0006491 12 8 0,000 0,02086152 0,06043009 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02086152 0,06035407 ! UTP metabolic process GO:0046051 8 8 0,000 0,02086152 0,06027825 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02086152 0,06020262 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02086152 0,06012718 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02086152 0,06005193 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02086152 0,05997686 ! succinate metabolic process GO:0006105 14 8 0,000 0,02086152 0,05990198 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02086152 0,05982729 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02086152 0,05975279 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02086152 0,05967847 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02086152 0,05960433 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02086152 0,05953038 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02086152 0,05945662 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02086152 0,05938303 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02086152 0,05930963 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02086152 0,05923641 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02086152 0,05916337 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02086152 0,0590905 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02086152 0,05901782 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02086152 0,05894532 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02086152 0,05887299 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02086152 0,05880084 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02086152 0,05872887 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02086152 0,05865708 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02086152 0,05858546 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02086152 0,05851401 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02086152 0,05844274 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02086152 0,05837164 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02086152 0,05830072 ! melanin metabolic process GO:0006582 12 8 0,000 0,02086152 0,05822996 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02086152 0,05815938 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02086152 0,05808897 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02086152 0,05801873 ! macrophage activation GO:0042116 12 8 0,000 0,02086152 0,05794866 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02086152 0,05787876 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02086152 0,05780902 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02086152 0,05773946 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02086152 0,05767006 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02086152 0,05760083 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02086152 0,05753176 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02086152 0,05746286 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02086152 0,05739413 ! ruffle organization GO:0031529 11 8 0,000 0,02086152 0,05732555 ! osteoblast development GO:0002076 13 8 0,000 0,02086152 0,05725715 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02086152 0,0571889 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02086152 0,05712082 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02086152 0,0570529 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02086152 0,05698514 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02086152 0,05691754 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02086152 0,05685011 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02086152 0,05678283 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02086152 0,05671571 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02086152 0,05664875 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02086152 0,05658194 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02086152 0,0565153 ! segment specification GO:0007379 10 8 0,000 0,02086152 0,05644881 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02086152 0,05638248 ! cellular extravasation GO:0045123 11 8 0,000 0,02086152 0,0563163 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02086152 0,05625028 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02086152 0,05618441 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02086152 0,0561187 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02086152 0,05605314 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02086152 0,05598774 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02086152 0,05592248 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02086152 0,05585738 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02086152 0,05579243 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02086152 0,05572763 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02086152 0,05566298 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02086152 0,05559848 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02086152 0,05553413 ! icosanoid secretion GO:0032309 12 8 0,000 0,02086152 0,05546993 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02086152 0,05540588 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02086152 0,05534197 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02086152 0,05527821 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02086152 0,0552146 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02086152 0,05515114 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02086152 0,05508782 ! sterol catabolic process GO:0016127 9 8 0,000 0,02086152 0,05502464 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02086152 0,05496161 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02086152 0,05489873 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02086152 0,05483599 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02086152 0,05477339 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02086152 0,05471093 ! prophase GO:0051324 11 8 0,000 0,02086152 0,05464862 ! S phase GO:0051320 8 8 0,000 0,02086152 0,05458645 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02086152 0,05452442 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02086152 0,05446253 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02086152 0,05440078 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02086152 0,05433917 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02086152 0,0542777 ! hormone catabolic process GO:0042447 13 8 0,000 0,02086152 0,05421637 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02086152 0,05415518 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02086152 0,05409413 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02086152 0,05403321 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02086152 0,05397243 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02086152 0,05391179 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02086152 0,05385128 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02086152 0,05379091 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02086152 0,05373067 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02086152 0,05367057 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02086152 0,0536106 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02086152 0,05355077 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02086152 0,05349107 ! regulation of embryonic development GO:0045995 16 8 0,000 0,02086152 0,0534315 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02086152 0,05337207 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02086152 0,05331277 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,02105539 0,0537485 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,02105539 0,05368892 ! regulation of protein localization GO:0032880 132 85 1,000 0,02105539 0,05362946 ! regulation of membrane potential GO:0042391 128 85 1,000 0,02105539 0,05357014 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,02105539 0,05351094 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,02152105 0,05463402 ! interphase of mitotic cell cycle GO:0051329 156 86 1,000 0,02152105 0,05457378 ! interphase GO:0051325 159 88 1,000 0,02246521 0,05690526 ! reproductive developmental process GO:0003006 127 89 1,000 0,02294365 0,05805325 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,02294365 0,05798945 ! regulation of T cell activation GO:0050863 128 89 1,000 0,02294365 0,0579258 ! leukocyte differentiation GO:0002521 143 90 1,000 0,02342631 0,05907952 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02343908 0,05904698 ! regulation of developmental growth GO:0048638 13 9 0,000 0,02343908 0,05898237 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,02343908 0,05891791 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02343908 0,05885359 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02343908 0,05878941 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02343908 0,05872537 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02343908 0,05866147 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02343908 0,0585977 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02343908 0,05853408 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02343908 0,0584706 ! GTP metabolic process GO:0046039 9 9 0,000 0,02343908 0,05840725 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02343908 0,05834404 ! social behavior GO:0035176 14 9 0,000 0,02343908 0,05828096 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02343908 0,05821802 ! artery development GO:0060840 19 9 0,000 0,02343908 0,05815522 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02343908 0,05809255 ! regulation of glycolysis GO:0006110 15 9 0,000 0,02343908 0,05803002 ! response to pain GO:0048265 16 9 0,000 0,02343908 0,05796762 ! protein complex disassembly GO:0043241 17 9 0,000 0,02343908 0,05790536 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02343908 0,05784323 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02343908 0,05778123 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02343908 0,05771937 ! lung alveolus development GO:0048286 17 9 0,000 0,02343908 0,05765763 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02343908 0,05759603 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02343908 0,05753457 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02343908 0,05747323 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02343908 0,05741202 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02343908 0,05735095 ! protein targeting to ER GO:0045047 19 9 0,000 0,02343908 0,05729 ! T cell selection GO:0045058 18 9 0,000 0,02343908 0,05722918 ! endoderm development GO:0007492 12 9 0,000 0,02343908 0,05716849 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02343908 0,05710793 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02343908 0,0570475 ! arginine catabolic process GO:0006527 10 9 0,000 0,02343908 0,0569872 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02343908 0,05692702 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02343908 0,05686697 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02343908 0,05680705 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02343908 0,05674725 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02343908 0,05668758 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02343908 0,05662803 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02343908 0,05656861 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02343908 0,05650932 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02343908 0,05645015 ! mannose metabolic process GO:0006013 9 9 0,000 0,02343908 0,0563911 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02343908 0,05633217 ! receptor clustering GO:0043113 15 9 0,000 0,02343908 0,05627337 ! epithelial cell development GO:0002064 10 9 0,000 0,02343908 0,05621469 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02343908 0,05615613 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02343908 0,0560977 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02343908 0,05603939 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02343908 0,05598119 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02343908 0,05592312 ! motor axon guidance GO:0008045 14 9 0,000 0,02343908 0,05586517 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02343908 0,05580734 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02343908 0,05574963 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02343908 0,05569203 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02343908 0,05563456 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02343908 0,0555772 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02343908 0,05551997 ! DNA ligation GO:0006266 14 9 0,000 0,02343908 0,05546285 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02343908 0,05540585 ! response to amine stimulus GO:0014075 13 9 0,000 0,02343908 0,05534896 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02343908 0,05529219 ! erythrocyte development GO:0048821 11 9 0,000 0,02343908 0,05523554 ! renal water homeostasis GO:0003091 14 9 0,000 0,02343908 0,05517901 ! postreplication repair GO:0006301 11 9 0,000 0,02343908 0,05512259 ! mRNA cleavage GO:0006379 13 9 0,000 0,02343908 0,05506628 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02343908 0,05501009 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02343908 0,05495401 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02343908 0,05489805 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02343908 0,05484221 ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02343908 0,05478647 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02343908 0,05473085 ! acid secretion GO:0046717 14 9 0,000 0,02343908 0,05467534 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02343908 0,05461995 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02343908 0,05456466 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02343908 0,05450949 ! purine base metabolic process GO:0006144 18 9 0,000 0,02343908 0,05445443 ! oocyte differentiation GO:0009994 12 9 0,000 0,02343908 0,05439948 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02343908 0,05434465 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02343908 0,05428992 ! spleen development GO:0048536 15 9 0,000 0,02343908 0,0542353 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02343908 0,05418079 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02343908 0,05412639 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02343908 0,0540721 ! detection of calcium ion GO:0005513 13 9 0,000 0,02343908 0,05401792 ! blastocyst formation GO:0001825 12 9 0,000 0,02343908 0,05396385 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02343908 0,05390989 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02343908 0,05385603 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02343908 0,05380228 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02343908 0,05374864 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02343908 0,05369511 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02343908 0,05364168 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02343908 0,05358836 ! prepulse inhibition GO:0060134 14 9 0,000 0,02343908 0,05353514 ! embryonic placenta development GO:0001892 12 9 0,000 0,02343908 0,05348203 ! insulin secretion GO:0030073 17 9 0,000 0,02343908 0,05342903 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02343908 0,05337613 ! response to nicotine GO:0035094 16 9 0,000 0,02343908 0,05332333 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02343908 0,05327064 ! nucleus localization GO:0051647 15 9 0,000 0,02343908 0,05321805 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02343908 0,05316557 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,02440417 0,05530009 ! cell fate commitment GO:0045165 141 92 1,000 0,02440417 0,05524566 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,02489932 0,05631115 ! angiogenesis GO:0001525 149 95 1,000 0,02590195 0,0585211 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02601001 0,05870758 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02601001 0,05865002 ! neuron fate specification GO:0048665 11 10 0,000 0,02601001 0,05859258 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02601001 0,05853524 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02601001 0,05847803 ! thyroid gland development GO:0030878 19 10 0,000 0,02601001 0,05842092 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02601001 0,05836392 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02601001 0,05830704 ! synapsis GO:0007129 13 10 0,000 0,02601001 0,05825026 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02601001 0,0581936 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02601001 0,05813705 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02601001 0,0580806 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02601001 0,05802427 ! sulfate transport GO:0008272 12 10 0,000 0,02601001 0,05796804 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02601001 0,05791193 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02601001 0,05785592 ! androgen metabolic process GO:0008209 13 10 0,000 0,02601001 0,05780002 ! hippocampus development GO:0021766 19 10 0,000 0,02601001 0,05774423 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02601001 0,05768854 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02601001 0,05763297 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02601001 0,0575775 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02601001 0,05752213 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02601001 0,05746688 ! pathogenesis GO:0009405 13 10 0,000 0,02601001 0,05741173 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02601001 0,05735668 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02601001 0,05730174 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02601001 0,05724691 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02601001 0,05719218 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02601001 0,05713755 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02601001 0,05708303 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02601001 0,05702862 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02601001 0,0569743 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02601001 0,0569201 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02601001 0,05686599 ! response to X-ray GO:0010165 16 10 0,000 0,02601001 0,05681198 ! B cell proliferation GO:0042100 14 10 0,000 0,02601001 0,05675808 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02601001 0,05670428 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02601001 0,05665059 ! forebrain cell migration GO:0021885 17 10 0,000 0,02601001 0,05659699 ! lipid digestion GO:0044241 15 10 0,000 0,02601001 0,0565435 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02601001 0,0564901 ! UV protection GO:0009650 14 10 0,000 0,02601001 0,05643681 ! entry into host cell GO:0030260 20 10 0,000 0,02601001 0,05638362 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02601001 0,05633053 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02601001 0,05627754 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02601001 0,05622464 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02601001 0,05617185 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02601001 0,05611916 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02601001 0,05606656 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02601001 0,05601406 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02601001 0,05596167 ! regulation of organ growth GO:0046620 11 10 0,000 0,02601001 0,05590936 ! response to dsRNA GO:0043331 18 10 0,000 0,02601001 0,05585716 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02601001 0,05580506 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02601001 0,05575305 ! embryonic axis specification GO:0000578 12 10 0,000 0,02601001 0,05570114 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02601001 0,05564932 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02601001 0,0555976 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02601001 0,05554598 ! cranial nerve development GO:0021545 12 10 0,000 0,02601001 0,05549445 ! fucose catabolic process GO:0019317 16 10 0,000 0,02601001 0,05544302 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02601001 0,05539169 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02601001 0,05534044 ! protein sumoylation GO:0016925 12 10 0,000 0,02601001 0,0552893 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02601001 0,05523825 ! zymogen activation GO:0031638 14 10 0,000 0,02601001 0,05518729 ! salivary gland development GO:0007431 22 10 0,000 0,02601001 0,05513642 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02601001 0,05508565 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02601001 0,05503498 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02601001 0,05498439 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02601001 0,0549339 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02601001 0,0548835 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02601001 0,0548332 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02601001 0,05478299 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02601001 0,05473286 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02601001 0,05468283 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02601001 0,05463289 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02601001 0,05458305 ! detection of bacterium GO:0016045 10 10 0,000 0,02601001 0,05453329 ! activation of innate immune response GO:0002218 10 10 0,000 0,02601001 0,05448362 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02601001 0,05443405 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02601001 0,05438456 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02601001 0,05433517 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02601001 0,05428586 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02601001 0,05423665 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,02640937 0,05501952 ! in utero embryonic development GO:0001701 147 96 1,000 0,02640937 0,05496973 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,02640937 0,05492003 ! response to light stimulus GO:0009416 153 96 1,000 0,02640937 0,05487042 ! extracellular structure organization GO:0043062 156 99 1,000 0,02795581 0,05803102 ! protein import GO:0017038 156 99 1,000 0,02795581 0,05797869 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,02847927 0,0590111 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,02847927 0,05895799 ! protein localization in organelle GO:0033365 161 100 1,000 0,02847927 0,05890497 ! rRNA transcription GO:0009303 17 11 0,000 0,02857431 0,05904845 ! respiratory burst GO:0045730 14 11 0,000 0,02857431 0,05899544 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02857431 0,05894253 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02857431 0,05888971 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02857431 0,05883699 ! virus-host interaction GO:0019048 17 11 0,000 0,02857431 0,05878437 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02857431 0,05873183 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02857431 0,05867939 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02857431 0,05862705 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02857431 0,0585748 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02857431 0,05852264 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02857431 0,05847057 ! mating GO:0007618 14 11 0,000 0,02857431 0,0584186 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02857431 0,05836672 ! T cell proliferation GO:0042098 20 11 0,000 0,02857431 0,05831493 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02857431 0,05826323 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02857431 0,05821162 ! bone resorption GO:0045453 16 11 0,000 0,02857431 0,05816011 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02857431 0,05810868 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02857431 0,05805735 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02857431 0,05800611 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02857431 0,05795496 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02857431 0,0579039 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02857431 0,05785292 ! syncytium formation GO:0006949 15 11 0,000 0,02857431 0,05780204 ! plasma membrane organization GO:0007009 18 11 0,000 0,02857431 0,05775125 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02857431 0,05770055 ! focal adhesion formation GO:0048041 24 11 0,000 0,02857431 0,05764993 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02857431 0,05759941 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02857431 0,05754897 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02857431 0,05749862 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02857431 0,05744836 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02857431 0,05739819 ! adult heart development GO:0007512 11 11 0,000 0,02857431 0,0573481 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02857431 0,0572981 ! temperature homeostasis GO:0001659 16 11 0,000 0,02857431 0,05724819 ! L-glutamate transport GO:0015813 16 11 0,000 0,02857431 0,05719837 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02857431 0,05714863 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02857431 0,05709898 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02857431 0,05704941 ! stem cell development GO:0048864 29 11 0,000 0,02857431 0,05699993 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02857431 0,05695054 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02857431 0,05690123 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02857431 0,05685201 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02857431 0,05680287 ! vasoconstriction GO:0042310 15 11 0,000 0,02857431 0,05675382 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02857431 0,05670485 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02857431 0,05665597 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02857431 0,05660717 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02857431 0,05655845 ! ribosome assembly GO:0042255 13 11 0,000 0,02857431 0,05650982 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02857431 0,05646127 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02857431 0,05641281 ! chromatin silencing GO:0006342 19 11 0,000 0,02857431 0,05636443 ! nucleosome positioning GO:0016584 13 11 0,000 0,02857431 0,05631613 ! T cell homeostasis GO:0043029 20 11 0,000 0,02857431 0,05626791 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02857431 0,05621978 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02857431 0,05617173 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02857431 0,05612376 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02857431 0,05607587 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02857431 0,05602807 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02857431 0,05598034 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02857431 0,0559327 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02857431 0,05588514 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02857431 0,05583766 ! male genitalia development GO:0030539 13 11 0,000 0,02857431 0,05579026 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02857431 0,05574294 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02857431 0,0556957 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02857431 0,05564854 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02857431 0,05560146 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02857431 0,05555446 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02857431 0,05550754 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02857431 0,05546069 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02857431 0,05541393 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02857431 0,05536725 ! lysogeny GO:0030069 18 11 0,000 0,02857431 0,05532064 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02857431 0,05527411 ! acrosome reaction GO:0007340 13 11 0,000 0,02857431 0,05522767 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02857431 0,05518129 ! lactation GO:0007595 20 12 0,000 0,03113201 0,06007016 ! reproductive cellular process GO:0048610 14 12 0,000 0,03113201 0,06001981 ! tRNA modification GO:0006400 14 12 0,000 0,03113201 0,05996954 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03113201 0,05991936 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03113201 0,05986926 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,03113201 0,05981924 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03113201 0,05976931 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03113201 0,05971946 ! non-recombinational repair GO:0000726 19 12 0,000 0,03113201 0,05966969 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03113201 0,05962001 ! peroxisomal transport GO:0043574 21 12 0,000 0,03113201 0,05957041 ! cartilage condensation GO:0001502 18 12 0,000 0,03113201 0,05952089 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03113201 0,05947146 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03113201 0,0594221 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03113201 0,05937283 ! heart looping GO:0001947 15 12 0,000 0,03113201 0,05932364 ! palate development GO:0060021 15 12 0,000 0,03113201 0,05927453 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03113201 0,0592255 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03113201 0,05917656 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03113201 0,05912769 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03113201 0,0590789 ! arginine metabolic process GO:0006525 13 12 0,000 0,03113201 0,0590302 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03113201 0,05898158 ! methionine metabolic process GO:0006555 13 12 0,000 0,03113201 0,05893303 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03113201 0,05888457 ! Golgi organization GO:0007030 18 12 0,000 0,03113201 0,05883618 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03113201 0,05878788 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03113201 0,05873965 ! monoamine transport GO:0015844 13 12 0,000 0,03113201 0,0586915 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03113201 0,05864343 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,03113201 0,05859544 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03113201 0,05854753 ! L-amino acid transport GO:0015807 20 12 0,000 0,03113201 0,0584997 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03113201 0,05845194 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03113201 0,05840427 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03113201 0,05835667 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03113201 0,05830915 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03113201 0,0582617 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03113201 0,05821434 ! cerebellum development GO:0021549 13 12 0,000 0,03113201 0,05816705 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03113201 0,05811983 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03113201 0,05807269 ! histone acetylation GO:0016573 23 12 0,000 0,03113201 0,05802563 ! histone methylation GO:0016571 15 12 0,000 0,03113201 0,05797865 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03113201 0,05793174 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03113201 0,05788491 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,03113201 0,05783815 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03113201 0,05779147 ! response to gamma radiation GO:0010332 20 12 0,000 0,03113201 0,05774486 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03113201 0,05769833 ! intestinal absorption GO:0050892 19 12 0,000 0,03113201 0,05765188 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03113201 0,0576055 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03113201 0,05755919 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03113201 0,05751296 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03113201 0,0574668 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03113201 0,05742072 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03113201 0,05737471 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03113201 0,05732877 ! microspike assembly GO:0030035 23 12 0,000 0,03113201 0,05728291 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03113201 0,05723712 ! response to cold GO:0009409 14 12 0,000 0,03113201 0,0571914 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,03368313 0,06182856 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,03368313 0,06177926 ! cGMP metabolic process GO:0046068 16 13 0,000 0,03368313 0,06173003 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,03368313 0,06168088 ! water transport GO:0006833 17 13 0,000 0,03368313 0,06163181 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,03368313 0,06158282 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,03368313 0,06153391 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,03368313 0,06148507 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,03368313 0,06143631 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,03368313 0,06138763 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,03368313 0,06133903 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,03368313 0,0612905 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,03368313 0,06124205 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,03368313 0,06119367 ! response to hexose stimulus GO:0009746 19 13 0,000 0,03368313 0,06114538 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,03368313 0,06109715 ! glutamate metabolic process GO:0006536 18 13 0,000 0,03368313 0,06104901 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,03368313 0,06100094 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,03368313 0,06095294 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,03368313 0,06090502 ! NAD metabolic process GO:0019674 21 13 0,000 0,03368313 0,06085718 ! exocrine system development GO:0035272 27 13 0,000 0,03368313 0,06080941 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,03368313 0,06076172 ! bone mineralization GO:0030282 15 13 0,000 0,03368313 0,0607141 ! regulation of exocytosis GO:0017157 17 13 0,000 0,03368313 0,06066655 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,03368313 0,06061908 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,03368313 0,06057169 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,03368313 0,06052437 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,03368313 0,06047712 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,03368313 0,06042995 ! genitalia development GO:0048806 15 13 0,000 0,03368313 0,06038285 ! regulation of cellular pH GO:0030641 20 13 0,000 0,03368313 0,06033582 ! cellular pigmentation GO:0033059 24 13 0,000 0,03368313 0,06028886 ! tissue regeneration GO:0042246 21 13 0,000 0,03368313 0,06024198 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,03368313 0,06019517 ! cofactor transport GO:0051181 19 13 0,000 0,03368313 0,06014844 ! NADP metabolic process GO:0006739 18 13 0,000 0,03368313 0,06010178 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,03368313 0,06005519 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,03368313 0,06000867 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03368313 0,05996222 ! gas transport GO:0015669 18 13 0,000 0,03368313 0,05991585 ! regulation of RNA stability GO:0043487 28 13 0,000 0,03368313 0,05986954 ! heme biosynthetic process GO:0006783 20 13 0,000 0,03368313 0,05982331 ! regulation of axon extension GO:0030516 23 13 0,000 0,03368313 0,05977715 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,03368313 0,05973106 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,03368313 0,05968505 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,03368313 0,0596391 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,03368313 0,05959322 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,03368313 0,05954742 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,03368313 0,05950168 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,03622767 0,06394753 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,03622767 0,06389849 ! superoxide anion generation GO:0042554 18 14 0,000 0,03622767 0,06384953 ! neuron maturation GO:0042551 21 14 0,000 0,03622767 0,06380064 ! regulation of S phase GO:0033261 18 14 0,000 0,03622767 0,06375182 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,03622767 0,06370308 ! myotube differentiation GO:0014902 21 14 0,000 0,03622767 0,06365442 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,03622767 0,06360583 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,03622767 0,06355731 ! inositol metabolic process GO:0006020 20 14 0,000 0,03622767 0,06350887 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,03622767 0,0634605 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,03622767 0,0634122 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,03622767 0,06336398 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,03622767 0,06331583 ! gene silencing by RNA GO:0031047 20 14 0,000 0,03622767 0,06326775 ! response to cAMP GO:0051591 19 14 0,000 0,03622767 0,06321975 ! limbic system development GO:0021761 25 14 0,000 0,03622767 0,06317182 ! startle response GO:0001964 21 14 0,000 0,03622767 0,06312396 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,03622767 0,06307618 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,03622767 0,06302847 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,03622767 0,06298083 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,03622767 0,06293326 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,03622767 0,06288576 ! glycine metabolic process GO:0006544 22 14 0,000 0,03622767 0,06283834 ! pituitary gland development GO:0021983 23 14 0,000 0,03622767 0,06279098 ! cellular response to starvation GO:0009267 21 14 0,000 0,03622767 0,0627437 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,03622767 0,06269649 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,03622767 0,06264935 ! regulation of heart rate GO:0002027 23 14 0,000 0,03622767 0,06260228 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,03622767 0,06255528 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,03622767 0,06250835 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,03622767 0,06246149 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,03622767 0,06241471 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,03622767 0,06236799 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,03622767 0,06232134 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,03622767 0,06227476 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,03622767 0,06222825 ! axon cargo transport GO:0008088 27 14 0,000 0,03622767 0,06218182 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,03622767 0,06213545 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,03622767 0,06208915 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,03622767 0,06204291 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03622767 0,06199675 ! mRNA splice site selection GO:0006376 26 14 0,000 0,03622767 0,06195066 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,03622767 0,06190463 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,03622767 0,06185867 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,03622767 0,06181278 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,03622767 0,06176696 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,03622767 0,06172121 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,03622767 0,06167552 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,03622767 0,06162991 ! muscle maintenance GO:0046716 19 14 0,000 0,03622767 0,06158436 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,03622767 0,06153887 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,03622767 0,06149346 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,03622767 0,06144811 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,03622767 0,06140282 ! cell killing GO:0001906 20 14 0,000 0,03622767 0,06135761 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,03622767 0,06131246 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,03622767 0,06126738 ! cilium assembly GO:0042384 20 14 0,000 0,03622767 0,06122236 ! peptide hormone secretion GO:0030072 23 14 0,000 0,03622767 0,06117741 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03876565 0,06541526 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03876565 0,0653673 ! metencephalon development GO:0022037 19 15 0,000 0,03876565 0,06531941 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03876565 0,0652716 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03876565 0,06522385 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03876565 0,06517617 ! skin development GO:0043588 25 15 0,000 0,03876565 0,06512856 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03876565 0,06508102 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03876565 0,06503355 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03876565 0,06498615 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03876565 0,06493882 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03876565 0,06489156 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03876565 0,06484436 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03876565 0,06479724 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03876565 0,06475018 ! adult walking behavior GO:0007628 25 15 0,000 0,03876565 0,06470319 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03876565 0,06465627 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03876565 0,06460942 ! myoblast differentiation GO:0045445 27 15 0,000 0,03876565 0,06456264 ! centrosome cycle GO:0007098 16 15 0,000 0,03876565 0,06451592 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03876565 0,06446927 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03876565 0,06442269 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03876565 0,06437617 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03876565 0,06432973 ! cerebral cortex development GO:0021987 29 15 0,000 0,03876565 0,06428334 ! response to osmotic stress GO:0006970 22 15 0,000 0,03876565 0,06423703 ! vesicle coating GO:0006901 25 15 0,000 0,03876565 0,06419078 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03876565 0,0641446 ! DNA integration GO:0015074 22 15 0,000 0,03876565 0,06409849 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,03876565 0,06405244 ! neuron recognition GO:0008038 22 15 0,000 0,03876565 0,06400646 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03876565 0,06396054 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03876565 0,06391469 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,03876565 0,06386891 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03876565 0,06382319 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03876565 0,06377754 ! biomineral formation GO:0031214 18 15 0,000 0,03876565 0,06373195 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03876565 0,06368643 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03876565 0,06364097 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03876565 0,06359558 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03876565 0,06355025 ! organic cation transport GO:0015695 19 15 0,000 0,03876565 0,06350499 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03876565 0,06345979 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03876565 0,06341465 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03876565 0,06336958 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03876565 0,06332457 ! defense response to virus GO:0051607 27 15 0,000 0,03876565 0,06327963 ! peptide hormone processing GO:0016486 19 15 0,000 0,03876565 0,06323475 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03876565 0,06318994 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,0412971 0,06726865 ! hormone secretion GO:0046879 25 16 0,000 0,0412971 0,06722104 ! bone remodeling GO:0046849 24 16 0,000 0,0412971 0,0671735 ! endothelial cell migration GO:0043542 22 16 0,000 0,0412971 0,06712603 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,0412971 0,06707862 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,0412971 0,06703128 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,0412971 0,06698401 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,0412971 0,06693681 ! glial cell development GO:0021782 24 16 0,000 0,0412971 0,06688967 ! patterning of blood vessels GO:0001569 24 16 0,000 0,0412971 0,06684259 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,0412971 0,06679559 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,0412971 0,06674865 ! protein polyubiquitination GO:0000209 26 16 0,000 0,0412971 0,06670177 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,0412971 0,06665497 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,0412971 0,06660822 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,0412971 0,06656155 ! fructose metabolic process GO:0006000 20 16 0,000 0,0412971 0,06651493 ! regulation of protein binding GO:0043393 27 16 0,000 0,0412971 0,06646839 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,0412971 0,06642191 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,0412971 0,06637549 ! protein export from nucleus GO:0006611 24 16 0,000 0,0412971 0,06632914 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,0412971 0,06628285 ! DNA replication initiation GO:0006270 25 16 0,000 0,0412971 0,06623663 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,0412971 0,06619047 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,0412971 0,06614438 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,0412971 0,06609835 ! diencephalon development GO:0021536 25 16 0,000 0,0412971 0,06605238 ! oogenesis GO:0048477 23 16 0,000 0,0412971 0,06600648 ! neural crest cell migration GO:0001755 24 16 0,000 0,0412971 0,06596064 ! G1 phase GO:0051318 27 16 0,000 0,0412971 0,06591487 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,0412971 0,06586916 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,0412971 0,06582351 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,0412971 0,06577793 ! steroid catabolic process GO:0006706 22 16 0,000 0,0412971 0,06573241 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,0412971 0,06568695 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,0412971 0,06564155 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,0412971 0,06559622 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,0412971 0,06555095 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,0412971 0,06550574 ! sperm-egg recognition GO:0035036 16 16 0,000 0,0412971 0,0654606 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,0412971 0,06541551 ! nerve development GO:0021675 18 16 0,000 0,0412971 0,06537049 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,0412971 0,06532553 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,0412971 0,06528064 ! negative regulation of translation GO:0017148 22 16 0,000 0,0412971 0,0652358 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,04382202 0,06917684 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,04382202 0,06912939 ! negative regulation of defense response GO:0031348 19 17 0,000 0,04382202 0,06908201 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,04382202 0,06903469 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,04382202 0,06898744 ! glycerol metabolic process GO:0006071 20 17 0,000 0,04382202 0,06894026 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,04382202 0,06889313 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,04382202 0,06884607 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,04382202 0,06879908 ! signal complex assembly GO:0007172 29 17 0,000 0,04382202 0,06875215 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,04382202 0,06870529 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,04382202 0,06865848 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,04382202 0,06861175 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,04382202 0,06856507 ! memory GO:0007613 25 17 0,000 0,04382202 0,06851846 ! keratinization GO:0031424 17 17 0,000 0,04382202 0,06847191 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,04382202 0,06842543 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,04382202 0,06837901 ! retinoid metabolic process GO:0001523 22 17 0,000 0,04382202 0,06833265 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,04382202 0,06828635 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,04382202 0,06824012 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,04382202 0,06819395 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,04382202 0,06814784 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,04382202 0,06810179 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,04382202 0,06805581 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,04382202 0,06800989 ! membrane budding GO:0006900 29 17 0,000 0,04382202 0,06796403 ! heme metabolic process GO:0042168 27 17 0,000 0,04382202 0,06791823 ! actin filament bundle formation GO:0051017 26 17 0,000 0,04382202 0,06787249 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,04382202 0,06782682 ! body fluid secretion GO:0007589 27 17 0,000 0,04382202 0,06778121 ! stem cell differentiation GO:0048863 36 17 0,000 0,04382202 0,06773565 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,04382202 0,06769016 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,04382202 0,06764473 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,04382202 0,06759937 ! sensory perception of pain GO:0019233 23 17 0,000 0,04382202 0,06755406 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,04382202 0,06750881 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,04382202 0,06746362 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,04382202 0,0674185 ! synaptogenesis GO:0007416 24 17 0,000 0,04382202 0,06737343 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,04382202 0,06732843 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,04382202 0,06728348 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,04382202 0,06723859 ! cell-cell junction organization GO:0045216 25 17 0,000 0,04382202 0,06719377 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,04382202 0,067149 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,04382202 0,0671043 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,04382202 0,06705965 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,04382202 0,06701506 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,04382202 0,06697053 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,04382202 0,06692606 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,04634044 0,07072529 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,04634044 0,07067839 ! positive regulation of translation GO:0045727 28 18 0,000 0,04634044 0,07063156 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,04634044 0,07058478 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,04634044 0,07053807 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,04634044 0,07049141 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,04634044 0,07044482 ! cAMP metabolic process GO:0046058 33 18 0,000 0,04634044 0,07039829 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,04634044 0,07035183 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,04634044 0,07030542 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,04634044 0,07025908 ! axis specification GO:0009798 26 18 0,000 0,04634044 0,07021279 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,04634044 0,07016657 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,04634044 0,07012041 ! pancreas development GO:0031016 26 18 0,000 0,04634044 0,0700743 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,04634044 0,07002826 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,04634044 0,06998228 ! glutamine metabolic process GO:0006541 23 18 0,000 0,04634044 0,06993636 ! response to retinoic acid GO:0032526 25 18 0,000 0,04634044 0,0698905 ! pigmentation during development GO:0048066 31 18 0,000 0,04634044 0,0698447 ! central nervous system neuron development GO:0021954 30 18 0,000 0,04634044 0,06979896 ! fucose metabolic process GO:0006004 26 18 0,000 0,04634044 0,06975328 ! response to fungus GO:0009620 19 18 0,000 0,04634044 0,06970766 ! peptide cross-linking GO:0018149 31 18 0,000 0,04634044 0,0696621 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,04634044 0,0696166 ! heart process GO:0003015 27 18 0,000 0,04634044 0,06957116 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,04634044 0,06952578 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,04634044 0,06948045 ! visual learning GO:0008542 35 18 0,000 0,04634044 0,06943519 ! somitogenesis GO:0001756 24 18 0,000 0,04634044 0,06938999 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,04634044 0,06934484 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,04634044 0,06929975 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,04634044 0,06925472 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,04634044 0,06920975 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,04634044 0,06916484 ! vitamin transport GO:0051180 24 18 0,000 0,04634044 0,06911999 ! hormone transport GO:0009914 27 18 0,000 0,04634044 0,06907519 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,04634044 0,06903045 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,04634044 0,06898577 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,04634044 0,06894115 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,04634044 0,06889659 ! cell-cell recognition GO:0009988 20 18 0,000 0,04634044 0,06885208 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,04634044 0,06880763 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,04634044 0,06876324 ! regulation of glucose import GO:0046324 21 18 0,000 0,04634044 0,0687189 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,04634044 0,06867462 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,04634044 0,0686304 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,04634044 0,06858624 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,04885237 0,07225753 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,04885237 0,07221109 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,04885237 0,07216471 ! positive regulation of ossification GO:0045778 30 19 0,000 0,04885237 0,07211839 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,04885237 0,07207213 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,04885237 0,07202593 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,04885237 0,07197979 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,04885237 0,07193371 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,04885237 0,07188769 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,04885237 0,07184172 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,04885237 0,07179582 ! regeneration GO:0031099 32 19 0,000 0,04885237 0,07174997 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,04885237 0,07170418 ! response to alkaloid GO:0043279 32 19 0,000 0,04885237 0,07165845 ! sensory perception of taste GO:0050909 23 19 0,000 0,04885237 0,07161278 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,04885237 0,07156717 ! smooth muscle contraction GO:0006939 36 19 0,000 0,04885237 0,07152161 ! peroxisome organization GO:0007031 29 19 0,000 0,04885237 0,07147612 ! digestive system process GO:0022600 30 19 0,000 0,04885237 0,07143068 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,04885237 0,0713853 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,04885237 0,07133997 ! response to vitamin A GO:0033189 26 19 0,000 0,04885237 0,07129471 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,04885237 0,0712495 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,04885237 0,07120434 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,04885237 0,07115925 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,04885237 0,07111421 ! response to starvation GO:0042594 30 19 0,000 0,04885237 0,07106923 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,04885237 0,07102431 ! plasma membrane fusion GO:0045026 23 19 0,000 0,04885237 0,07097944 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,04885237 0,07093463 ! cytolysis GO:0019835 20 19 0,000 0,04885237 0,07088988 ! renal system process GO:0003014 35 19 0,000 0,04885237 0,07084518 ! vasodilation GO:0042311 33 19 0,000 0,04885237 0,07080054 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,04885237 0,07075595 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,04885237 0,07071143 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,04885237 0,07066695 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,04885237 0,07062254 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,04885237 0,07057818 ! sarcomere organization GO:0045214 23 19 0,000 0,04885237 0,07053387 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,04885237 0,07048962 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,04885237 0,07044543 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,04885237 0,07040129 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,04885237 0,0703572 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,04885237 0,07031318 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,04885237 0,0702692 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,04885237 0,07022528 ! protein stabilization GO:0050821 26 19 0,000 0,04885237 0,07018142 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,05135783 0,07373471 ! iron ion transport GO:0006826 37 20 0,000 0,05135783 0,07368871 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,05135783 0,07364277 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,05135783 0,07359689 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,05135783 0,07355106 ! response to vitamin GO:0033273 29 20 0,000 0,05135783 0,07350529 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,05135783 0,07345958 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,05135783 0,07341393 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,05135783 0,07336833 ! spinal cord development GO:0021510 31 20 0,000 0,05135783 0,07332278 ! response to ethanol GO:0045471 37 20 0,000 0,05135783 0,0732773 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,05135783 0,07323187 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,05135783 0,0731865 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,05135783 0,07314118 ! chromosome condensation GO:0030261 31 20 0,000 0,05135783 0,07309592 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,05135783 0,07305071 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,05135783 0,07300557 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,05135783 0,07296047 ! pallium development GO:0021543 38 20 0,000 0,05135783 0,07291544 ! DNA modification GO:0006304 28 20 0,000 0,05135783 0,07287045 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,05135783 0,07282553 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,05135783 0,07278066 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,05135783 0,07273584 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,05135783 0,07269108 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,05135783 0,07264637 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,05135783 0,07260172 ! collagen catabolic process GO:0030574 25 20 0,000 0,05135783 0,07255713 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,05135783 0,07251259 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,05135783 0,0724681 ! alditol metabolic process GO:0019400 24 20 0,000 0,05135783 0,07242367 ! actin filament-based movement GO:0030048 34 20 0,000 0,05135783 0,07237929 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,05385683 0,07585469 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,05385683 0,07580827 GO:0016444|somatic cell DNA recombination, ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,05385683 0,0757619 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,05385683 0,07571559 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,05385683 0,07566934 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,05385683 0,07562314 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,05385683 0,075577 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,05385683 0,07553092 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,05385683 0,07548489 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,05385683 0,07543892 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,05385683 0,075393 ! protein amino acid acylation GO:0043543 37 21 0,000 0,05385683 0,07534714 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,05385683 0,07530134 ! phototransduction GO:0007602 25 21 0,000 0,05385683 0,07525559 ! dendrite development GO:0016358 35 21 0,000 0,05385683 0,0752099 ! visual behavior GO:0007632 39 21 0,000 0,05385683 0,07516426 ! ovarian follicle development GO:0001541 30 21 0,000 0,05385683 0,07511868 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,05385683 0,07507316 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,05385683 0,07502768 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,05385683 0,07498227 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,05385683 0,07493691 ! cell aging GO:0007569 32 21 0,000 0,05385683 0,0748916 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,05385683 0,07484635 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,05385683 0,07480115 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,05385683 0,07475601 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,05385683 0,07471092 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,05385683 0,07466589 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,05385683 0,07462091 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,05385683 0,07457598 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,05385683 0,07453111 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,05385683 0,07448629 ! fatty acid transport GO:0015908 30 21 0,000 0,05385683 0,07444153 ! immunoglobulin production GO:0002377 33 21 0,000 0,05385683 0,07439682 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,05385683 0,07435216 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,05385683 0,07430756 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,05385683 0,07426301 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,05385683 0,07421852 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,05385683 0,07417408 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,05385683 0,07412969 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,05385683 0,07408535 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,05385683 0,07404107 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,05385683 0,07399684 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,05385683 0,07395266 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,05385683 0,07390854 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,05385683 0,07386446 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,05385683 0,07382044 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,05385683 0,07377648 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,05634939 0,077145 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,05634939 0,0770991 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,05634939 0,07705327 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,05634939 0,07700748 ! viral genome replication GO:0019079 29 22 0,000 0,05634939 0,07696175 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,05634939 0,07691608 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,05634939 0,07687046 ! leukocyte adhesion GO:0007159 38 22 0,000 0,05634939 0,07682489 ! molting cycle process GO:0022404 40 22 0,000 0,05634939 0,07677938 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,05634939 0,07673392 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,05634939 0,07668852 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,05634939 0,07664317 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,05634939 0,07659787 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,05634939 0,07655262 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,05634939 0,07650743 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,05634939 0,0764623 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,05634939 0,07641721 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,05634939 0,07637218 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,05634939 0,0763272 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,05634939 0,07628228 ! regulation of behavior GO:0050795 38 22 0,000 0,05634939 0,07623741 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,05634939 0,07619259 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,05634939 0,07614782 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,05634939 0,07610311 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,05634939 0,07605845 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,05634939 0,07601384 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,05634939 0,07596928 ! blastocyst development GO:0001824 37 22 0,000 0,05634939 0,07592478 ! neural tube closure GO:0001843 33 22 0,000 0,05634939 0,07588032 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,05634939 0,07583592 ! protein tetramerization GO:0051262 39 22 0,000 0,05634939 0,07579158 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,05883552 0,07908925 ! neuron fate commitment GO:0048663 32 23 0,000 0,05883552 0,07904305 ! embryonic pattern specification GO:0009880 31 23 0,000 0,05883552 0,07899691 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,05883552 0,07895082 ! myelination GO:0042552 35 23 0,000 0,05883552 0,07890478 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,05883552 0,0788588 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,05883552 0,07881287 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,05883552 0,078767 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,05883552 0,07872118 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,05883552 0,07867541 ! vesicle targeting GO:0006903 32 23 0,000 0,05883552 0,0786297 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,05883552 0,07858403 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,05883552 0,07853842 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,05883552 0,07849287 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,05883552 0,07844737 ! interaction with host GO:0051701 37 23 0,000 0,05883552 0,07840192 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,05883552 0,07835652 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,05883552 0,07831117 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,05883552 0,07826588 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,05883552 0,07822064 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,05883552 0,07817545 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,05883552 0,07813031 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,05883552 0,07808523 ! cell fate determination GO:0001709 45 23 0,000 0,05883552 0,0780402 ! pentose metabolic process GO:0019321 31 23 0,000 0,05883552 0,07799522 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,05883552 0,07795029 ! spermatid development GO:0007286 33 23 0,000 0,05883552 0,07790541 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,05883552 0,07786059 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,05883552 0,07781582 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,05883552 0,0777711 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,05883552 0,07772642 ! telomere organization GO:0032200 32 23 0,000 0,05883552 0,07768181 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,05883552 0,07763724 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,05883552 0,07759272 ! regulation of amine transport GO:0051952 38 23 0,000 0,05883552 0,07754826 ! liver development GO:0001889 40 23 0,000 0,05883552 0,07750384 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,06131525 0,08072414 ! initiation of viral infection GO:0019059 42 24 0,000 0,06131525 0,08067796 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,06131525 0,08063183 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,06131525 0,08058576 ! superoxide metabolic process GO:0006801 32 24 0,000 0,06131525 0,08053974 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,06131525 0,08049377 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,06131525 0,08044785 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,06131525 0,08040198 ! sperm motility GO:0030317 27 24 0,000 0,06131525 0,08035617 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,06131525 0,08031041 ! receptor metabolic process GO:0043112 37 24 0,000 0,06131525 0,0802647 ! neural crest cell development GO:0014032 39 24 0,000 0,06131525 0,08021904 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,06131525 0,08017344 ! primary neural tube formation GO:0014020 35 24 0,000 0,06131525 0,08012789 ! negative regulation of cell development GO:0010721 56 24 0,000 0,06131525 0,08008238 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,06131525 0,08003693 ! base-excision repair GO:0006284 31 24 0,000 0,06131525 0,07999154 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,06131525 0,07994619 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,06131525 0,07990089 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,06131525 0,07985565 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,06131525 0,07981046 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,06131525 0,07976532 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,06378859 0,08293598 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,06378859 0,08288913 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,06378859 0,08284232 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,06378859 0,08279557 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,06378859 0,08274887 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,06378859 0,08270223 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,06378859 0,08265563 GO:0045936|negative regulation of phosphate metabolic process, ! iron ion homeostasis GO:0055072 39 25 0,000 0,06378859 0,08260909 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,06378859 0,08256261 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,06378859 0,08251617 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,06378859 0,08246979 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,06378859 0,08242346 ! detection of light stimulus GO:0009583 30 25 0,000 0,06378859 0,08237718 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,06378859 0,08233095 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,06378859 0,08228477 ! leukocyte proliferation GO:0070661 39 25 0,000 0,06378859 0,08223865 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,06378859 0,08219258 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,06625555 0,08532349 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,06625555 0,08527575 ! translational initiation GO:0006413 43 26 0,000 0,06625555 0,08522805 ! regulation of pH GO:0006885 36 26 0,000 0,06625555 0,08518041 ! circadian rhythm GO:0007623 42 26 0,000 0,06625555 0,08513283 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,06625555 0,08508529 ! post-embryonic development GO:0009791 42 26 0,000 0,06625555 0,08503781 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,06625555 0,08499038 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,06625555 0,08494301 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,06625555 0,08489569 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,06625555 0,08484842 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,06625555 0,0848012 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,06625555 0,08475404 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,06871615 0,08785277 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,06871615 0,08780397 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,06871615 0,08775521 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,06871615 0,08770652 ! catechol metabolic process GO:0009712 43 27 0,000 0,06871615 0,08765787 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,06871615 0,08760928 ! acute-phase response GO:0006953 42 27 0,000 0,06871615 0,08756074 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,06871615 0,08751226 ! myofibril assembly GO:0030239 36 27 0,000 0,06871615 0,08746383 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,06871615 0,08741545 ! response to ionizing radiation GO:0010212 47 27 0,000 0,06871615 0,08736713 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,06871615 0,08731886 ! natural killer cell activation GO:0030101 35 27 0,000 0,06871615 0,08727065 ! lipid oxidation GO:0034440 38 27 0,000 0,06871615 0,08722248 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,06871615 0,08717437 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,06871615 0,08712632 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,06871615 0,08707831 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,06871615 0,08703036 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,06871615 0,08698247 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,06871615 0,08693462 ! gene silencing GO:0016458 41 27 0,000 0,06871615 0,08688683 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,07117041 0,08994062 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,07117041 0,08989123 ! phenol metabolic process GO:0018958 44 28 0,000 0,07117041 0,0898419 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,07117041 0,08979261 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,07117041 0,08974338 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,07117041 0,08969421 ! cell junction assembly GO:0034329 56 28 0,000 0,07117041 0,08964509 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,07117041 0,08959602 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,07117041 0,08954701 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,07117041 0,08949805 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,07117041 0,08944914 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,07117041 0,08940029 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,07117041 0,08935149 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,07117041 0,08930275 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,07117041 0,08925405 ! mesoderm formation GO:0001707 46 28 0,000 0,07117041 0,08920541 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,07117041 0,08915683 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,07117041 0,08910829 ! ensheathment of neurons GO:0007272 43 28 0,000 0,07117041 0,08905981 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,07117041 0,08901138 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,07117041 0,08896301 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,07117041 0,08891468 ! neural tube formation GO:0001841 41 28 0,000 0,07117041 0,08886641 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,07117041 0,08881819 ! placenta development GO:0001890 37 28 0,000 0,07117041 0,08877003 ! regulation of B cell activation GO:0050864 42 28 0,000 0,07117041 0,08872191 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,07361834 0,09172382 ! regulation of innate immune response GO:0045088 38 29 0,000 0,07361834 0,09167416 ! ovulation cycle process GO:0022602 41 29 0,000 0,07361834 0,09162455 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,07361834 0,091575 ! protein targeting to membrane GO:0006612 53 29 0,000 0,07361834 0,0915255 ! mismatch repair GO:0006298 34 29 0,000 0,07361834 0,09147605 ! muscle cell development GO:0055001 38 29 0,000 0,07361834 0,09142666 ! formation of primary germ layer GO:0001704 48 29 0,000 0,07361834 0,09137732 ! telencephalon development GO:0021537 52 29 0,000 0,07361834 0,09132803 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,07361834 0,0912788 ! eye morphogenesis GO:0048592 51 29 0,000 0,07361834 0,09122962 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,07361834 0,09118049 ! tissue homeostasis GO:0001894 42 29 0,000 0,07361834 0,09113142 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,07605995 0,09410322 ! collagen metabolic process GO:0032963 40 30 0,000 0,07605995 0,09405263 ! organic anion transport GO:0015711 51 30 0,000 0,07605995 0,09400209 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,07605995 0,09395161 ! spliceosome assembly GO:0000245 49 30 0,000 0,07605995 0,09390118 ! spindle organization GO:0007051 37 30 0,000 0,07605995 0,0938508 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,07605995 0,09380048 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,07605995 0,09375021 ! ceramide metabolic process GO:0006672 43 30 0,000 0,07605995 0,0937 ! ovulation cycle GO:0042698 43 30 0,000 0,07605995 0,09364984 ! hindbrain development GO:0030902 45 30 0,000 0,07605995 0,09359973 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,07605995 0,09354967 ! adult locomotory behavior GO:0008344 47 30 0,000 0,07605995 0,09349967 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,07605995 0,09344973 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,07605995 0,09339984 ! response to heat GO:0009408 41 30 0,000 0,07605995 0,09335 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,07605995 0,09330021 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,07605995 0,09325048 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,07849528 0,09618494 ! negative regulation of secretion GO:0051048 49 31 0,000 0,07849528 0,09613372 ! glial cell differentiation GO:0010001 55 31 0,000 0,07849528 0,09608256 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,07849528 0,09603145 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,07849528 0,0959804 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,07849528 0,0959294 ! odontogenesis GO:0042476 50 31 0,000 0,07849528 0,09587846 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,07849528 0,09582757 ! segmentation GO:0035282 41 31 0,000 0,07849528 0,09577673 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,07849528 0,09572595 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,07849528 0,09567522 ! metanephros development GO:0001656 58 31 0,000 0,07849528 0,09562454 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,07849528 0,09557392 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,07849528 0,09552335 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,07849528 0,09547284 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,07849528 0,09542237 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,07849528 0,09537197 ! RNA modification GO:0009451 40 31 0,000 0,07849528 0,09532161 ! regulation of muscle development GO:0048634 48 32 0,000 0,08092432 0,09821949 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,08092432 0,09816768 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,08092432 0,09811594 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,08092432 0,09806424 ! meiosis I GO:0007127 52 32 0,000 0,08092432 0,0980126 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,08092432 0,09796102 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,08092432 0,09790948 ! peripheral nervous system development GO:0007422 53 32 0,000 0,08092432 0,09785801 ! regulation of protein stability GO:0031647 48 32 0,000 0,08092432 0,09780658 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,08092432 0,09775522 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,08092432 0,0977039 ! vesicle localization GO:0051648 47 32 0,000 0,08092432 0,09765264 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,0833471 0,1005235 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,0833471 0,10047082 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,0833471 0,10041819 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,0833471 0,10036561 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,0833471 0,10031309 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,0833471 0,10026063 ! sister chromatid segregation GO:0000819 46 33 0,000 0,0833471 0,10020822 ! actomyosin structure organization GO:0031032 43 33 0,000 0,0833471 0,10015586 ! cell junction organization GO:0034330 63 33 0,000 0,0833471 0,10010356 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,0833471 0,10005132 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,0833471 0,09999912 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,0833471 0,09994699 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,0833471 0,0998949 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,0833471 0,09984288 ! female gonad development GO:0008585 49 33 0,000 0,0833471 0,0997909 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,0833471 0,09973898 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,0833471 0,09968711 ! regulation of proteolysis GO:0030162 50 33 0,000 0,0833471 0,0996353 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,0833471 0,09958354 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,0833471 0,09953184 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,0833471 0,09948019 ! cytokinesis GO:0000910 52 33 0,000 0,0833471 0,09942859 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,0833471 0,09937705 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,08576363 0,10220536 ! mRNA catabolic process GO:0006402 48 34 0,000 0,08576363 0,10215243 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,08576363 0,10209955 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,08576363 0,10204674 ! feeding behavior GO:0007631 45 34 0,000 0,08576363 0,10199397 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,08576363 0,10194126 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,08576363 0,10188861 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,08576363 0,101836 ! neuron migration GO:0001764 46 34 0,000 0,08576363 0,10178346 ! female gamete generation GO:0007292 43 34 0,000 0,08576363 0,10173096 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,08576363 0,10167853 ! polyol metabolic process GO:0019751 44 34 0,000 0,08576363 0,10162614 ! aerobic respiration GO:0009060 47 34 0,000 0,08576363 0,10157381 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,08576363 0,10152153 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,08817392 0,104321 ! Notch signaling pathway GO:0007219 56 35 0,000 0,08817392 0,10426736 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,08817392 0,10421378 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,08817392 0,10416026 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,08817392 0,10410679 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,08817392 0,10405337 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,08817392 0,10400001 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,08817392 0,10394671 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,08817392 0,10389345 ! glycogen metabolic process GO:0005977 48 35 0,000 0,08817392 0,10384026 ! pigment metabolic process GO:0042440 61 35 0,000 0,08817392 0,10378712 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,08817392 0,10373403 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,090578 0,10650788 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,090578 0,10645345 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,090578 0,10639909 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,090578 0,10634477 ! negative regulation of binding GO:0051100 58 36 0,000 0,090578 0,10629052 ! neural tube development GO:0021915 50 36 0,000 0,090578 0,10623631 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,090578 0,10618217 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,090578 0,10612807 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,090578 0,10607404 ! glucan metabolic process GO:0044042 49 36 0,000 0,090578 0,10602006 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,09297588 0,10877138 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,09297588 0,10871608 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,09297588 0,10866084 ! learning GO:0007612 67 37 0,000 0,09297588 0,10860565 ! ion transmembrane transport GO:0034220 56 37 0,000 0,09297588 0,10855052 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,09297588 0,10849545 ! regulation of protein secretion GO:0050708 51 37 0,000 0,09297588 0,10844043 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,09297588 0,10838547 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,09536758 0,11111724 ! gliogenesis GO:0042063 71 38 0,000 0,09536758 0,11106098 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,09536758 0,11100477 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,09536758 0,11094862 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,09536758 0,11089253 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,09536758 0,1108365 ! mesenchymal cell development GO:0014031 64 38 0,000 0,09536758 0,11078052 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,09536758 0,1107246 ! maintenance of location in cell GO:0051651 69 38 0,000 0,09536758 0,11066873 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,0977531 0,1133798 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,0977531 0,11332265 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,0977531 0,11326556 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,0977531 0,11320853 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,0977531 0,11315155 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,0977531 0,11309464 ! chromatin remodeling GO:0006338 68 39 0,000 0,0977531 0,11303778 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,0977531 0,11298097 ! JNK cascade GO:0007254 54 39 0,000 0,0977531 0,11292423 ! developmental growth GO:0048589 62 39 0,000 0,0977531 0,11286754 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,10013247 0,11555679 ! response to calcium ion GO:0051592 58 40 0,000 0,10013247 0,11549884 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,10013247 0,11544095 ! regulation of tube size GO:0035150 60 40 0,000 0,10013247 0,11538311 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,10013247 0,11532533 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,10013247 0,11526761 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,10013247 0,11520995 ! peptide metabolic process GO:0006518 56 40 0,000 0,10013247 0,11515234 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,10013247 0,1150948 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,10013247 0,11503731 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,10013247 0,11497987 ! B cell differentiation GO:0030183 62 40 0,000 0,10013247 0,1149225 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,10013247 0,11486518 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,10013247 0,11480792 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,10013247 0,11475072 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,10250571 0,11741191 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,10250571 0,11735347 ! glucose transport GO:0015758 52 41 0,000 0,10250571 0,11729509 ! striated muscle contraction GO:0006941 62 41 0,000 0,10250571 0,11723676 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,10250571 0,11717849 ! biopolymer methylation GO:0043414 62 41 0,000 0,10250571 0,11712028 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,10250571 0,11706213 ! mitochondrial transport GO:0006839 60 42 0,000 0,10487281 0,11970594 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,10487281 0,11964656 ! cellular component disassembly GO:0022411 64 42 0,000 0,10487281 0,11958724 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,10487281 0,11952798 ! hexose transport GO:0008645 54 42 0,000 0,10487281 0,11946878 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,10487281 0,11940964 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,10487281 0,11935055 ! excretion GO:0007588 63 42 0,000 0,10487281 0,11929153 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,10487281 0,11923256 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,10487281 0,11917365 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,10487281 0,1191148 ! positive regulation of binding GO:0051099 59 43 0,000 0,10723381 0,12173631 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,10723381 0,12167626 ! leukocyte migration GO:0050900 60 43 0,000 0,10723381 0,12161626 ! neuromuscular process GO:0050905 79 43 0,000 0,10723381 0,12155632 ! activation of caspase activity GO:0006919 65 43 0,000 0,10723381 0,12149644 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,10723381 0,12143662 ! tRNA processing GO:0008033 49 43 0,000 0,10723381 0,12137686 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,10723381 0,12131715 ! methylation GO:0032259 64 43 0,000 0,10723381 0,12125751 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,10958872 0,12385949 ! glycolysis GO:0006096 53 44 0,000 0,10958872 0,12379866 ! regulation of action potential GO:0001508 71 44 0,000 0,10958872 0,12373788 ! regulation of ion transport GO:0043269 57 44 0,000 0,10958872 0,12367716 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,10958872 0,12361651 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,10958872 0,12355591 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,10958872 0,12349538 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,10958872 0,1234349 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,10958872 0,12337448 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,10958872 0,12331412 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,10958872 0,12325382 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,10958872 0,12319358 ! RNA catabolic process GO:0006401 64 45 0,000 0,11193755 0,12577253 ! positive regulation of defense response GO:0031349 59 45 0,000 0,11193755 0,12571112 ! regulation of translational initiation GO:0006446 64 45 0,000 0,11193755 0,12564977 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,11193755 0,12558847 ! cell recognition GO:0008037 58 45 0,000 0,11193755 0,12552724 ! cell maturation GO:0048469 60 45 0,000 0,11193755 0,12546607 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,11428032 0,12802959 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,11428032 0,12796726 ! cell redox homeostasis GO:0045454 63 46 0,000 0,11428032 0,12790498 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,11428032 0,12784277 ! regulation of ossification GO:0030278 71 46 0,000 0,11428032 0,12778062 ! histone modification GO:0016570 68 46 0,000 0,11428032 0,12771853 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,11661705 0,13026673 ! viral infectious cycle GO:0019058 71 47 0,000 0,11661705 0,1302035 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,11661705 0,13014032 ! endocrine system development GO:0035270 83 47 0,000 0,11661705 0,13007721 ! covalent chromatin modification GO:0016569 75 47 0,000 0,11661705 0,13001416 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,11661705 0,12995117 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,11661705 0,12988824 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,11661705 0,12982537 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,11661705 0,12976256 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,11661705 0,12969981 ! chloride transport GO:0006821 67 48 0,000 0,11894774 0,13222803 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,11894774 0,13216415 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,11894774 0,13210034 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,11894774 0,13203658 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,11894774 0,13197289 ! gastrulation GO:0007369 73 48 0,000 0,11894774 0,13190926 ! heart morphogenesis GO:0003007 65 48 0,000 0,11894774 0,13184569 ! regulation of DNA replication GO:0006275 75 48 0,000 0,11894774 0,13178218 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,11894774 0,13171873 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,11894774 0,13165534 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,11894774 0,13159201 ! regulation of endocytosis GO:0030100 63 48 0,000 0,11894774 0,13152875 ! nuclear export GO:0051168 69 48 0,000 0,11894774 0,13146554 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,11894774 0,1314024 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,12127241 0,13390617 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,12127241 0,13384192 ! sensory perception of smell GO:0007608 61 49 0,000 0,12127241 0,13377772 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,12127241 0,13371359 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,12127241 0,13364952 ! RNA elongation GO:0006354 62 49 0,000 0,12127241 0,13358551 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,12127241 0,13352157 ! germ cell development GO:0007281 68 49 0,000 0,12127241 0,13345768 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,12127241 0,13339386 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,12127241 0,13333009 ! maintenance of location GO:0051235 84 49 0,000 0,12127241 0,13326639 ! regulation of actin filament length GO:0030832 72 50 0,000 0,12359109 0,13574953 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,12359109 0,13568473 ! positive regulation of growth GO:0045927 67 50 0,000 0,12359109 0,13561999 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,12359109 0,13555532 ! proton transport GO:0015992 75 50 0,000 0,12359109 0,13549071 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,12359109 0,13542616 ! positive regulation of secretion GO:0051047 71 51 0,000 0,12590378 0,13789462 ! hydrogen transport GO:0006818 77 51 0,000 0,12590378 0,13782898 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,12590378 0,13776341 ! adult behavior GO:0030534 80 51 0,000 0,12590378 0,1376979 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,12590378 0,13763246 ! transition metal ion transport GO:0000041 74 52 0,000 0,1282105 0,14008748 ! regulation of cellular component size GO:0032535 74 52 0,000 0,1282105 0,14002096 ! aging GO:0007568 79 52 0,000 0,1282105 0,13995451 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,1282105 0,13988812 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,1282105 0,13982179 ! establishment of organelle localization GO:0051656 85 52 0,000 0,1282105 0,13975552 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,13051126 0,14219607 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,13051126 0,14212874 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,13051126 0,14206148 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,13051126 0,14199428 ! kidney development GO:0001822 90 53 0,000 0,13051126 0,14192714 ! single fertilization GO:0007338 59 53 0,000 0,13051126 0,14186007 ! cell projection assembly GO:0030031 76 53 0,000 0,13051126 0,14179306 ! amino acid transport GO:0006865 84 54 0,000 0,13280609 0,14421813 ! regulation of mitosis GO:0007088 84 54 0,000 0,13280609 0,14415007 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,13280609 0,14408208 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,13280609 0,14401414 ! DNA catabolic process GO:0006308 67 54 0,000 0,13280609 0,14394628 ! detection of external stimulus GO:0009581 66 54 0,000 0,13280609 0,14387847 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,13280609 0,14381073 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,13280609 0,14374306 ! exocytosis GO:0006887 74 55 0,000 0,13509499 0,14615168 ! mesoderm development GO:0007498 76 55 0,000 0,13509499 0,14608296 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,13509499 0,14601432 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,13509499 0,14594573 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,13737797 0,14834241 ! carbohydrate transport GO:0008643 74 57 0,000 0,13965507 0,15073048 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,13965507 0,15065978 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,13965507 0,15058915 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,13965507 0,15051858 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,13965507 0,15044808 ! camera-type eye development GO:0043010 88 57 0,000 0,13965507 0,15037765 ! secondary metabolic process GO:0019748 84 57 0,000 0,13965507 0,15030728 ! developmental maturation GO:0021700 75 57 0,000 0,13965507 0,15023697 ! viral reproductive process GO:0022415 87 58 0,000 0,14192628 0,1526089 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,14192628 0,15253759 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,14192628 0,15246634 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,14192628 0,15239516 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,14419162 0,15475536 ! activation of MAPK activity GO:0000187 84 59 0,000 0,14419162 0,15468318 ! actin filament organization GO:0007015 95 59 0,000 0,14419162 0,15461107 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,14419162 0,15453902 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,14419162 0,15446704 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,14645112 0,15681451 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,14645112 0,15674154 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,14645112 0,15666864 ! regulation of heart contraction GO:0008016 91 60 0,000 0,14645112 0,1565958 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,14645112 0,15652304 ! fertilization GO:0009566 68 60 0,000 0,14645112 0,15645034 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,14645112 0,1563777 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,14870478 0,15871044 ! meiosis GO:0007126 96 61 0,000 0,14870478 0,15863682 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,14870478 0,15856328 ! urogenital system development GO:0001655 101 61 0,000 0,14870478 0,1584898 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,14870478 0,15841639 ! extracellular matrix organization GO:0030198 103 61 0,000 0,14870478 0,15834305 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,14870478 0,15826978 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,14870478 0,15819657 ! amine catabolic process GO:0009310 90 62 0,000 0,15095262 0,16051365 ! neurotransmitter transport GO:0006836 81 62 0,000 0,15095262 0,16043947 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,15095262 0,16036537 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,15095262 0,16029133 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,15095262 0,16021736 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,15095262 0,16014346 ! meiotic cell cycle GO:0051321 97 62 0,000 0,15095262 0,16006962 ! organelle localization GO:0051640 96 62 0,000 0,15095262 0,15999586 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,15319465 0,16229741 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,15319465 0,16222269 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,15319465 0,16214804 ! viral reproduction GO:0016032 92 63 0,000 0,15319465 0,16207345 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,15543089 0,1643637 ! negative regulation of cell size GO:0045792 108 64 0,000 0,15543089 0,16428816 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,15543089 0,1642127 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,15543089 0,1641373 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,15543089 0,16406197 ! hexose catabolic process GO:0019320 82 64 0,000 0,15543089 0,16398671 ! adaptive immune response GO:0002250 94 64 0,000 0,15543089 0,16391153 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! B cell activation GO:0042113 104 65 0,000 0,15766135 0,16618749 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,15766135 0,16611136 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,15766135 0,1660353 ! defense response to bacterium GO:0042742 73 65 0,000 0,15766135 0,16595931 ! activation of immune response GO:0002253 83 65 0,000 0,15766135 0,16588339 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,15988605 0,16814719 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,15988605 0,16807034 ! antigen processing and presentation GO:0019882 96 66 0,000 0,15988605 0,16799356 ! axon guidance GO:0007411 99 66 0,000 0,15988605 0,16791685 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,162105 0,17016955 ! acute inflammatory response GO:0002526 92 68 0,000 0,16431821 0,17241418 ! learning or memory GO:0007611 123 68 0,000 0,16431821 0,17233556 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,16431821 0,17225701 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,16431821 0,17217854 ! rhythmic process GO:0048511 105 68 0,000 0,16431821 0,17210013 ! inorganic anion transport GO:0015698 93 68 0,000 0,16431821 0,1720218 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,16652571 0,17425347 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,16652571 0,17417423 ! response to drug GO:0042493 108 69 0,000 0,16652571 0,17409506 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,16652571 0,17401596 ! response to metal ion GO:0010038 103 70 0,000 0,1687275 0,17623672 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,1687275 0,17615672 ! humoral immune response GO:0006959 86 70 0,000 0,1687275 0,1760768 ! eye development GO:0001654 111 70 0,000 0,1687275 0,17599694 ! amine transport GO:0015837 101 70 0,000 0,1687275 0,17591716 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,1687275 0,17583745 ! regulation of catabolic process GO:0009894 106 70 0,000 0,1687275 0,17575782 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,17092361 0,17796482 ! muscle cell differentiation GO:0042692 104 71 0,000 0,17092361 0,1778843 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,17092361 0,17780384 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,17092361 0,17772346 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,17092361 0,17764315 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,17092361 0,17756291 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,17311403 0,17975723 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,17311403 0,17967612 ! negative regulation of transport GO:0051051 116 73 0,000 0,1752988 0,18186163 ! regulation of blood pressure GO:0008217 107 73 0,000 0,1752988 0,18177964 ! tube morphogenesis GO:0035239 118 73 0,000 0,1752988 0,18169772 ! mitochondrion organization GO:0007005 104 73 0,000 0,1752988 0,18161587 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,1752988 0,1815341 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,1752988 0,1814524 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,17747791 0,18362537 ! digestion GO:0007586 97 74 0,000 0,17747791 0,18354281 ! response to inorganic substance GO:0010035 115 75 0,000 0,1796514 0,18570706 ! negative regulation of growth GO:0045926 123 75 0,000 0,1796514 0,18562364 ! response to nutrient GO:0007584 104 75 0,000 0,1796514 0,18554029 ! regulation of ligase activity GO:0051340 114 75 0,000 0,1796514 0,18545701 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,1796514 0,18537381 ! amine biosynthetic process GO:0009309 97 76 0,000 0,18181926 0,1875266 ! response to unfolded protein GO:0006986 99 76 0,000 0,18181926 0,18744254 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,18398153 0,1895867 ! regulation of DNA binding GO:0051101 119 77 0,000 0,18398153 0,1895018 ! protein ubiquitination GO:0016567 125 77 0,000 0,18398153 0,18941697 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,18398153 0,18933222 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,18398153 0,18924754 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,18398153 0,18916295 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,1861382 0,19129484 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,1861382 0,1912094 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,1861382 0,19112404 ! cellular respiration GO:0045333 107 79 0,000 0,18828929 0,19324648 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,18828929 0,19316029 ! regulation of lyase activity GO:0051339 133 79 0,000 0,18828929 0,19307417 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,18828929 0,19298813 ! chromatin assembly GO:0031497 102 80 0,000 0,19043482 0,19510026 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,19043482 0,1950134 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,19043482 0,19492661 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 0,000 0,19043482 0,1948399 ! mRNA transport GO:0051028 121 81 0,000 0,19257481 0,19694178 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,19257481 0,19685425 ! response to protein stimulus GO:0051789 111 81 0,000 0,19257481 0,19676679 ! regulation of neurological system process GO:0031644 122 81 0,000 0,19257481 0,19667942 ! vitamin metabolic process GO:0006766 103 81 0,000 0,19257481 0,19659212 ! detection of stimulus GO:0051606 108 82 0,000 0,19470926 0,19868291 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,19683819 0,20076622 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,19683819 0,20067723 ! regulation of defense response GO:0031347 117 84 0,000 0,19896161 0,20275219 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,19896161 0,2026624 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,19896161 0,20257269 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,20107954 0,20463847 ! rRNA metabolic process GO:0016072 107 85 0,000 0,20107954 0,20454796 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,20107954 0,20445753 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,20107954 0,20436719 ! cell cycle arrest GO:0007050 150 86 0,000 0,20319199 0,20642296 ! nucleosome organization GO:0034728 114 87 0,000 0,20529898 0,20847137 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,20529898 0,20837937 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,20529898 0,20828745 ! female pregnancy GO:0007565 130 87 0,000 0,20529898 0,20819562 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,20529898 0,20810386 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,20740052 0,21014149 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,20740052 0,21004896 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,20740052 0,20995651 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,20740052 0,20986414 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,20740052 0,20977185 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,20949662 0,21179878 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,2115873 0,21381845 ! hormone metabolic process GO:0042445 121 90 0,000 0,2115873 0,21372454 ! RNA localization GO:0006403 135 91 0,000 0,21367256 0,21573613 ! ATP metabolic process GO:0046034 137 91 0,000 0,21367256 0,21564147 ! response to virus GO:0009615 122 91 0,000 0,21367256 0,21554689 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,21575244 0,21754959 ! positive regulation of immune response GO:0050778 121 92 0,000 0,21575244 0,21745425 ! DNA recombination GO:0006310 146 92 0,000 0,21575244 0,217359 ! sulfur metabolic process GO:0006790 118 92 0,000 0,21575244 0,21726384 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,21782693 0,21925686 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,21782693 0,21916095 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,21782693 0,21906512 ! electron transport chain GO:0022900 123 94 0,000 0,21989605 0,22104935 ! response to oxidative stress GO:0006979 141 94 0,000 0,21989605 0,22095278 ! regulation of binding GO:0051098 151 95 0,000 0,22195982 0,22292907 ! carboxylic acid transport GO:0046942 147 95 0,000 0,22195982 0,22283177 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,22401824 0,22480016 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,22401824 0,22470212 ! protein maturation GO:0051604 129 96 0,000 0,22401824 0,22460417 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,22607134 0,22656387 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,22607134 0,22646519 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,23016161 0,23046221 ! regulation of translation GO:0006417 151 100 0,000 0,2321988 0,23240089 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,2321988 0,2322998 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,2321988 0,2321988