pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/809-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of axonogenesis GO:0050772 28 15 2,000 4,488E-06 0,01079872 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,116E-05 0,01342239 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,503E-05 0,01205015 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 2,233E-05 0,0134344 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 2,832E-05 0,01362526 ! cholesterol homeostasis GO:0042632 53 31 2,000 4,324E-05 0,01733983 GO:0055092|sterol homeostasis, ! regulation of cell morphogenesis GO:0022604 215 89 3,000 4,464E-05 0,01534432 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 1,000 4,71E-05 0,01416469 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,71E-05 0,01259083 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,71E-05 0,01133175 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 4,71E-05 0,01030159 GO:0002707|negative regulation of lymphocyte mediated immunity, ! secretory granule organization GO:0033363 11 5 1,000 4,71E-05 9,443E-03 ! cholesterol transport GO:0030301 56 32 2,000 4,764E-05 8,817E-03 ! regulation of axonogenesis GO:0050770 75 32 2,000 4,764E-05 8,187E-03 ! regulation of ARF GTPase activity GO:0032312 65 32 2,000 4,764E-05 7,641E-03 ! positive regulation of neurogenesis GO:0050769 67 33 2,000 5,232E-05 7,868E-03 ! sterol transport GO:0015918 57 33 2,000 5,232E-05 7,405E-03 ! positive regulation of cell development GO:0010720 80 36 2,000 6,815E-05 9,109E-03 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 1,000 7,055E-05 8,933E-03 GO:0030816|positive regulation of cAMP metabolic process, ! male sex determination GO:0030238 15 6 1,000 7,055E-05 8,487E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 7,055E-05 8,083E-03 ! regulation of neuron projection development GO:0010975 91 38 2,000 8,027E-05 8,778E-03 ! lipid homeostasis GO:0055088 67 38 2,000 8,027E-05 8,397E-03 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 2,000 8,027E-05 8,047E-03 ! Rho protein signal transduction GO:0007266 74 39 2,000 8,682E-05 8,356E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 9,863E-05 9,127E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 9,863E-05 8,789E-03 ! vesicle fusion GO:0006906 17 7 1,000 9,863E-05 8,475E-03 ! lymph node development GO:0048535 10 7 1,000 9,863E-05 8,183E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 9,863E-05 7,91E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 9,863E-05 7,655E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 9,863E-05 7,415E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,165E-04 8,495E-03 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 1,000 1,313E-04 9,292E-03 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,313E-04 9,027E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 1,313E-04 8,776E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,313E-04 8,539E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,313E-04 8,314E-03 ! intracellular lipid transport GO:0032365 13 8 1,000 1,313E-04 8,101E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,313E-04 7,899E-03 ! cell growth GO:0016049 84 45 2,000 1,335E-04 7,837E-03 ! protein homooligomerization GO:0051260 76 47 2,000 1,521E-04 8,715E-03 ! regulation of ARF protein signal transduction GO:0032012 102 48 2,000 1,62E-04 9,065E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,686E-04 9,219E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,686E-04 9,014E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,686E-04 8,818E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,686E-04 8,631E-03 ! induction of an organ GO:0001759 14 9 1,000 1,686E-04 8,451E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 1,686E-04 8,278E-03 GO:0002820|negative regulation of adaptive immune response, ! regulation of cell projection organization GO:0031344 121 50 2,000 1,83E-04 8,807E-03 ! vesicle organization GO:0016050 107 51 2,000 1,942E-04 9,16E-03 ! phospholipid efflux GO:0033700 16 10 1,000 2,104E-04 9,737E-03 ! reverse cholesterol transport GO:0043691 16 10 1,000 2,104E-04 9,553E-03 ! phagocytosis, engulfment GO:0006911 28 10 1,000 2,104E-04 9,376E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 2,104E-04 9,206E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,104E-04 9,042E-03 ! negative regulation of immune effector process GO:0002698 20 10 1,000 2,104E-04 8,883E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 2,104E-04 8,73E-03 ! localization within membrane GO:0051668 20 10 1,000 2,104E-04 8,582E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,568E-04 0,01029952 ! chondrocyte differentiation GO:0002062 24 11 1,000 2,568E-04 0,01013068 ! cholesterol efflux GO:0033344 19 11 1,000 2,568E-04 9,967E-03 ! embryonic gut development GO:0048566 15 11 1,000 2,568E-04 9,809E-03 ! developmental induction GO:0031128 19 11 1,000 2,568E-04 9,656E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 3,078E-04 0,01139256 ! gland morphogenesis GO:0022612 29 12 1,000 3,078E-04 0,01121995 ! lipid localization GO:0010876 28 13 1,000 3,632E-04 0,01304355 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 3,632E-04 0,01285173 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,632E-04 0,01266547 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 3,632E-04 0,01248454 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 3,984E-04 0,01350162 GO:0035113|embryonic appendage morphogenesis, ! lung development GO:0030324 144 67 2,000 4,356E-04 0,01455637 ! regulation of vasodilation GO:0042312 26 15 1,000 4,876E-04 0,0160699 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 4,876E-04 0,01585274 ! appendage morphogenesis GO:0035107 135 70 2,000 4,954E-04 0,01589326 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 2,000 4,954E-04 0,01568413 ! appendage development GO:0048736 136 71 2,000 5,165E-04 0,01613818 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 5,165E-04 0,01593128 ! respiratory system development GO:0060541 153 72 2,000 5,381E-04 0,0163879 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 5,564E-04 0,01673491 ! negative regulation of immune response GO:0050777 35 16 1,000 5,564E-04 0,01652831 ! embryonic digit morphogenesis GO:0042733 34 16 1,000 5,564E-04 0,01632674 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,564E-04 0,01613003 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 6,297E-04 0,01803754 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,297E-04 0,01782533 ! protein oligomerization GO:0051259 139 78 2,000 6,8E-04 0,01902364 ! regulation of peptidase activity GO:0052547 134 79 2,000 7,057E-04 0,0195168 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 7,075E-04 0,01934248 ! regulation of neuron differentiation GO:0045664 167 81 2,000 7,59E-04 0,02051974 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 7,866E-04 0,02102948 ! protein secretion GO:0009306 39 19 1,000 7,896E-04 0,02087583 ! lipid phosphorylation GO:0046834 35 19 1,000 7,896E-04 0,02064892 ! neuromuscular junction development GO:0007528 34 19 1,000 7,896E-04 0,02042689 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 8,761E-04 0,02242336 ! peptide secretion GO:0002790 35 20 1,000 8,761E-04 0,02218733 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 8,761E-04 0,02195621 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 8,761E-04 0,02172986 ! regulation of cell killing GO:0031341 42 21 1,000 9,669E-04 0,02373855 ! inactivation of MAPK activity GO:0000188 39 21 1,000 9,669E-04 0,02349877 ! regulation of vasoconstriction GO:0019229 39 21 1,000 9,669E-04 0,02326378 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 9,669E-04 0,02303344 ! gut development GO:0048565 39 21 1,000 9,669E-04 0,02280763 ! ossification GO:0001503 188 90 2,000 1,031E-03 0,02407357 ! lysosome organization GO:0007040 41 22 1,000 1,062E-03 0,02457116 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 1,062E-03 0,02433715 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,062E-03 0,02410755 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,062E-03 0,02388225 ! bone development GO:0060348 189 91 2,000 1,064E-03 0,02370476 ! regulation of DNA recombination GO:0000018 48 23 1,000 1,162E-03 0,02564054 ! sex determination GO:0007530 47 23 1,000 1,162E-03 0,02540744 ! vesicle docking GO:0048278 47 24 1,000 1,265E-03 0,02742872 ! vacuole organization GO:0007033 43 24 1,000 1,265E-03 0,02718382 ! membrane depolarization GO:0051899 39 24 1,000 1,265E-03 0,02694325 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,265E-03 0,02670691 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,357E-03 0,02838606 GO:0060538|skeletal muscle organ development, ! vasculogenesis GO:0001570 46 25 1,000 1,374E-03 0,02848846 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,374E-03 0,02824497 ! osteoblast differentiation GO:0001649 60 25 1,000 1,374E-03 0,02800561 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,374E-03 0,02777026 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,486E-03 0,02979163 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,486E-03 0,02954542 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,486E-03 0,02930324 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 1,486E-03 0,029065 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 1,486E-03 0,02883061 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,602E-03 0,03084436 ! male gonad development GO:0008584 44 27 1,000 1,602E-03 0,03059956 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 1,723E-03 0,03264776 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,848E-03 0,03474306 ! regulation of coagulation GO:0050818 46 29 1,000 1,848E-03 0,03447373 ! membrane docking GO:0022406 61 30 1,000 1,978E-03 0,03660031 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,978E-03 0,03632092 ! phospholipid transport GO:0015914 51 30 1,000 1,978E-03 0,03604576 ! inner ear morphogenesis GO:0042472 47 31 1,000 2,111E-03 0,03818801 ! peptide transport GO:0015833 55 31 1,000 2,111E-03 0,03790303 ! triglyceride metabolic process GO:0006641 43 31 1,000 2,111E-03 0,03762226 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,249E-03 0,03977915 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 2,249E-03 0,03948879 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 2,249E-03 0,03920264 ! cell fate specification GO:0001708 52 33 1,000 2,39E-03 0,04137318 ! neutral lipid metabolic process GO:0006638 50 35 1,000 2,686E-03 0,04615973 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 2,686E-03 0,04583235 ! cytokine production GO:0001816 59 35 1,000 2,686E-03 0,04550959 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,686E-03 0,04519134 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 2,84E-03 0,04745039 ! embryonic organ development GO:0048568 57 36 1,000 2,84E-03 0,04712314 ! tissue remodeling GO:0048771 76 37 1,000 2,998E-03 0,04940496 ! glycerol ether metabolic process GO:0006662 53 37 1,000 2,998E-03 0,04906887 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 2,998E-03 0,04873732 ! mammary gland development GO:0030879 86 39 1,000 3,326E-03 0,05371015 ! ear morphogenesis GO:0042471 60 39 1,000 3,326E-03 0,05335208 ! organic ether metabolic process GO:0018904 55 39 1,000 3,326E-03 0,05299875 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 3,326E-03 0,05265008 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 3,326E-03 0,05230596 ! T cell differentiation GO:0030217 81 41 1,000 3,67E-03 0,05734468 ! regulation of T cell differentiation GO:0045580 70 41 1,000 3,67E-03 0,05697472 ! hormone-mediated signaling GO:0009755 74 41 1,000 3,67E-03 0,0566095 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 3,849E-03 0,0589782 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 3,849E-03 0,05860492 ! phagocytosis GO:0006909 90 43 1,000 4,031E-03 0,06099113 ! male sex differentiation GO:0046661 76 44 1,000 4,217E-03 0,06340673 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 4,217E-03 0,0630129 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 4,406E-03 0,06544442 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 4,6E-03 0,06790371 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 4,6E-03 0,06748966 ! response to insulin stimulus GO:0032868 95 46 1,000 4,6E-03 0,06708064 ! positive regulation of protein transport GO:0051222 72 46 1,000 4,6E-03 0,06667653 ! endosome transport GO:0016197 108 47 1,000 4,798E-03 0,06912552 ! regulation of adaptive immune response GO:0002819 84 47 1,000 4,798E-03 0,06871406 ! positive regulation of cell cycle GO:0045787 89 48 1,000 5E-03 0,07117707 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 5E-03 0,07075838 ! protein amino acid lipidation GO:0006497 95 49 1,000 5,205E-03 0,07323481 ! inner ear development GO:0048839 79 50 1,000 5,414E-03 0,07573606 ! negative regulation of immune system process GO:0002683 95 50 1,000 5,414E-03 0,07529828 ! embryonic skeletal system development GO:0048706 85 51 1,000 5,627E-03 0,07781169 ! regulation of cell shape GO:0008360 125 51 1,000 5,627E-03 0,07736705 ! regulation of muscle contraction GO:0006937 81 52 1,000 5,844E-03 0,07989207 ! membrane fusion GO:0006944 110 52 1,000 5,844E-03 0,0794407 ! amino acid activation GO:0043038 92 52 1,000 5,844E-03 0,0789944 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 5,844E-03 0,07855309 ! synapse organization GO:0050808 85 52 1,000 5,844E-03 0,07811669 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 6,065E-03 0,08061808 ! regulation of protein polymerization GO:0032271 103 53 1,000 6,065E-03 0,08017512 ! response to UV GO:0009411 104 53 1,000 6,065E-03 0,07973701 ! activation of phospholipase C activity GO:0007202 103 54 1,000 6,289E-03 0,08223803 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,517E-03 0,08476076 ! skeletal muscle fiber development GO:0048741 111 56 1,000 6,749E-03 0,08730461 ! positive regulation of organelle organization GO:0010638 100 56 1,000 6,749E-03 0,08683774 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 6,985E-03 0,08939101 ! muscle fiber development GO:0048747 112 57 1,000 6,985E-03 0,08891804 ! positive regulation of cell migration GO:0030335 126 57 1,000 6,985E-03 0,08845005 ! lipid modification GO:0030258 97 57 1,000 6,985E-03 0,08798696 ! regulation of phospholipase activity GO:0010517 106 57 1,000 6,985E-03 0,0875287 ! regulation of intracellular transport GO:0032386 101 57 1,000 6,985E-03 0,08707518 ! positive regulation of lipase activity GO:0060193 108 58 1,000 7,224E-03 0,0895941 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 7,714E-03 0,09517573 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 7,714E-03 0,09469014 ! regulation of protein complex assembly GO:0043254 117 61 1,000 7,964E-03 0,09726626 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 7,964E-03 0,09677501 ! ear development GO:0043583 103 62 1,000 8,218E-03 0,09935865 ! gonad development GO:0008406 98 62 1,000 8,218E-03 0,09886185 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 8,475E-03 0,10145265 ! positive regulation of cell motion GO:0051272 146 64 1,000 8,737E-03 0,10406062 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 9,541E-03 0,1130865 ! homeostasis of number of cells GO:0048872 114 67 1,000 9,541E-03 0,11253215 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 9,541E-03 0,11198321 ! positive regulation of T cell activation GO:0050870 109 67 1,000 9,541E-03 0,11143961 ! negative regulation of kinase activity GO:0033673 131 68 1,000 9,817E-03 0,11410164 ! regulation of lipase activity GO:0060191 130 68 1,000 9,817E-03 0,11355307 ! reproductive structure development GO:0048608 113 71 1,000 0,01066378 0,12276104 ! regulation of immune effector process GO:0002697 137 71 1,000 0,01066378 0,12217646 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01091007 0,1244058 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01091007 0,12381898 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01091007 0,12323767 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01091007 0,1226618 ! neuron fate determination GO:0048664 7 5 0,000 0,01091007 0,12209128 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01091007 0,12152604 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01091007 0,12096601 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01091007 0,12041112 ! polyol transport GO:0015791 12 5 0,000 0,01091007 0,1198613 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01091007 0,11931648 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01091007 0,11877658 ! response to superoxide GO:0000303 10 5 0,000 0,01091007 0,11824155 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01091007 0,11771132 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01091007 0,11718582 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01091007 0,116665 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01091007 0,11614878 ! female meiosis GO:0007143 7 5 0,000 0,01091007 0,11563711 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01091007 0,11512993 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01091007 0,11462718 ! cobalt ion transport GO:0006824 11 5 0,000 0,01091007 0,1141288 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01091007 0,11363474 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01091007 0,11314493 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01091007 0,11265933 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01091007 0,11217788 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01091007 0,11170053 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01091007 0,11122722 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01091007 0,11075791 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01091007 0,11029254 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01091007 0,10983107 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01091007 0,10937344 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01091007 0,1089196 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01091007 0,10846952 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01091007 0,10802315 ! negative chemotaxis GO:0050919 14 5 0,000 0,01091007 0,10758043 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01091007 0,10714133 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01091007 0,10670579 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01091007 0,10627378 ! behavioral response to pain GO:0048266 9 5 0,000 0,01091007 0,10584526 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01091007 0,10542018 ! Notch receptor processing GO:0007220 8 5 0,000 0,01091007 0,1049985 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01091007 0,10458018 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01091007 0,10416518 ! micturition GO:0060073 9 5 0,000 0,01091007 0,10375346 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01091007 0,10334498 ! copulation GO:0007620 9 5 0,000 0,01091007 0,1029397 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01091007 0,1025376 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01091007 0,10213862 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01091007 0,10174273 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01091007 0,1013499 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01091007 0,1009601 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01091007 0,10057327 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01091007 0,10018941 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01091007 0,09980846 ! grooming behavior GO:0007625 6 5 0,000 0,01091007 0,0994304 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01091007 0,09905519 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01091007 0,0986828 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01091007 0,0983132 ! response to protozoan GO:0001562 10 5 0,000 0,01091007 0,09794636 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01091007 0,09758225 ! lymph vessel development GO:0001945 10 5 0,000 0,01091007 0,09722083 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01091007 0,09686208 ! endochondral ossification GO:0001958 16 5 0,000 0,01091007 0,09650597 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01091007 0,09615247 ! parathyroid gland development GO:0060017 13 5 0,000 0,01091007 0,09580155 ! anagen GO:0042640 6 5 0,000 0,01091007 0,09545318 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01091007 0,09510734 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01091007 0,09476399 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01091007 0,09442311 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01091007 0,09408468 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01091007 0,09374866 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01091007 0,09341503 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01091007 0,09308378 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01091007 0,09275486 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01091007 0,09242826 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01091007 0,09210395 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01091007 0,0917819 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01091007 0,09146211 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01091007 0,09114453 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01091007 0,09082915 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01091007 0,09051595 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01091007 0,0902049 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01091007 0,08989598 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01091007 0,08958916 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01091007 0,08928444 ! histidine catabolic process GO:0006548 6 5 0,000 0,01091007 0,08898178 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01091007 0,08868116 ! microvillus organization GO:0032528 7 5 0,000 0,01091007 0,08838257 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01091007 0,08808599 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01091007 0,08779139 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01091007 0,08749875 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01091007 0,08720806 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01091007 0,08691929 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01091007 0,08663242 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01091007 0,08634745 ! polyol catabolic process GO:0046174 7 5 0,000 0,01091007 0,08606434 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01091007 0,08578309 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01091007 0,08550366 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01091007 0,08522605 ! muscle cell migration GO:0014812 8 5 0,000 0,01091007 0,08495024 ! mitochondrial fission GO:0000266 8 5 0,000 0,01091007 0,08467621 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01091007 0,08440394 ! mRNA transcription GO:0009299 9 5 0,000 0,01091007 0,08413341 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01091007 0,08386462 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01091007 0,08359753 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01091007 0,08333214 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01091007 0,08306843 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01091007 0,08280639 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01091007 0,08254599 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01091007 0,08228722 ! response to food GO:0032094 6 5 0,000 0,01091007 0,08203008 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01091007 0,08177453 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01091007 0,08152057 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01091007 0,08126819 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01091007 0,08101736 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01091007 0,08076808 ! forebrain neuron development GO:0021884 13 5 0,000 0,01091007 0,08052032 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01091007 0,08027408 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01091007 0,08002934 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01091007 0,07978609 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01091007 0,07954432 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01091007 0,079304 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01091007 0,07906513 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01091007 0,0788277 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01091007 0,07859169 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01091007 0,07835709 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01091007 0,07812388 ! basic amino acid transport GO:0015802 11 5 0,000 0,01091007 0,07789206 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01091007 0,07766161 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01091007 0,07743252 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01091007 0,07720478 ! depyrimidination GO:0045008 10 5 0,000 0,01091007 0,07697837 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01091007 0,07675329 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01091007 0,07652952 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01091007 0,07630705 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01091007 0,07608587 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01091007 0,07586597 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01091007 0,07564733 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01091007 0,07542996 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01091007 0,07521382 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01091007 0,07499893 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01091007 0,07478526 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01091007 0,0745728 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01091007 0,07436154 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01091007 0,07415148 ! response to arsenic GO:0046685 10 5 0,000 0,01091007 0,0739426 ! mast cell degranulation GO:0043303 7 5 0,000 0,01091007 0,0737349 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01091007 0,07352836 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01091007 0,07332297 ! response to cadmium ion GO:0046686 7 5 0,000 0,01091007 0,07311873 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01091007 0,07291562 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01091007 0,07271364 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01091007 0,07251278 ! decidualization GO:0046697 11 5 0,000 0,01091007 0,07231302 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01091007 0,07211435 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01091007 0,07191678 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01091007 0,07172029 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01091007 0,07152486 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01091007 0,0713305 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01091007 0,07113719 ! neural tube patterning GO:0021532 7 5 0,000 0,01091007 0,07094493 ! embryonic cleavage GO:0040016 6 5 0,000 0,01091007 0,07075371 ! peroxisome fission GO:0016559 5 5 0,000 0,01091007 0,07056351 ! histone demethylation GO:0016577 10 5 0,000 0,01091007 0,07037433 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01091007 0,07018616 ! mitotic recombination GO:0006312 9 5 0,000 0,01091007 0,069999 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01091007 0,06981283 ! metaphase plate congression GO:0051310 7 5 0,000 0,01091007 0,06962765 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01091007 0,06944345 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01091007 0,06926022 ! enteric nervous system development GO:0048484 8 5 0,000 0,01091007 0,06907796 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01091007 0,06889665 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01091007 0,0687163 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01091007 0,06853688 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01091007 0,0683584 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01091007 0,06818084 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01091007 0,06800421 ! plasminogen activation GO:0031639 5 5 0,000 0,01091007 0,06782849 ! B cell homeostasis GO:0001782 13 5 0,000 0,01091007 0,06765367 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01091007 0,06747976 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01091007 0,06730673 ! metaphase GO:0051323 8 5 0,000 0,01091007 0,06713459 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01091007 0,06696333 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01091007 0,06679294 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01091007 0,06662341 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01091007 0,06645475 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01091007 0,06628693 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01091007 0,06611996 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01091007 0,06595383 ! response to redox state GO:0051775 5 5 0,000 0,01091007 0,06578853 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01091007 0,06562406 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01091007 0,06546041 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01091007 0,06529757 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01091007 0,06513555 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01091007 0,06497432 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01091007 0,06481389 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01091007 0,06465425 ! striatum development GO:0021756 9 5 0,000 0,01091007 0,06449539 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01091007 0,06433732 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01091007 0,06418001 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01091007 0,06402347 ! glial cell migration GO:0008347 11 5 0,000 0,01091007 0,0638677 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01091007 0,06371268 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01091007 0,06355841 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01091007 0,06340489 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01091007 0,06325211 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01091007 0,06310006 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01091007 0,06294874 ! neuroprotection GO:0043526 6 5 0,000 0,01091007 0,06279815 ! neural plate development GO:0001840 8 5 0,000 0,01091007 0,06264827 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01091007 0,06249911 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01091007 0,06235065 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01091007 0,0622029 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01091007 0,06205585 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01091007 0,06190949 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01091007 0,06176382 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01091007 0,06161884 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01091007 0,06147453 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01091007 0,0613309 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01091007 0,06118794 ! spindle assembly GO:0051225 6 5 0,000 0,01091007 0,06104564 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01091007 0,060904 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01091007 0,06076302 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01091007 0,06062269 ! drug metabolic process GO:0017144 6 5 0,000 0,01091007 0,06048301 ! stem cell division GO:0017145 11 5 0,000 0,01091007 0,06034396 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01091007 0,06020556 ! organ regeneration GO:0031100 7 5 0,000 0,01091007 0,06006779 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01091007 0,05993065 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01091007 0,05979413 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01091007 0,05965824 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01095309 0,05975765 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01095309 0,05962246 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,01095309 0,05948787 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,01124584 0,0609403 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01154203 0,06240478 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,01184164 0,06388112 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,01214465 0,06536917 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01245104 0,06686876 ! blood coagulation GO:0007596 146 78 1,000 0,01276081 0,06837973 GO:0050817|coagulation, ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01307392 0,06990192 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01307797 0,06976852 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01307797 0,06961417 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01307797 0,06946049 ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01307797 0,06930749 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01307797 0,06915517 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01307797 0,06900351 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01307797 0,06885252 ! sleep GO:0030431 13 6 0,000 0,01307797 0,06870219 ! response to oxygen radical GO:0000305 11 6 0,000 0,01307797 0,06855251 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01307797 0,06840348 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01307797 0,0682551 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01307797 0,06810736 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01307797 0,06796026 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01307797 0,0678138 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01307797 0,06766796 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01307797 0,06752275 ! forebrain regionalization GO:0021871 8 6 0,000 0,01307797 0,06737816 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01307797 0,06723419 ! male meiosis GO:0007140 7 6 0,000 0,01307797 0,06709084 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01307797 0,06694809 ! response to zinc ion GO:0010043 9 6 0,000 0,01307797 0,06680595 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01307797 0,06666441 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01307797 0,06652347 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01307797 0,06638313 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01307797 0,06624337 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01307797 0,06610421 ! malate metabolic process GO:0006108 11 6 0,000 0,01307797 0,06596562 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01307797 0,06582762 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01307797 0,06569019 ! protein refolding GO:0042026 15 6 0,000 0,01307797 0,06555334 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01307797 0,06541705 ! opsonization GO:0008228 8 6 0,000 0,01307797 0,06528133 ! mating behavior GO:0007617 7 6 0,000 0,01307797 0,06514618 ! neuron remodeling GO:0016322 15 6 0,000 0,01307797 0,06501158 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01307797 0,06487753 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01307797 0,06474404 ! equilibrioception GO:0050957 14 6 0,000 0,01307797 0,06461109 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01307797 0,06447869 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01307797 0,06434684 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01307797 0,06421552 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01307797 0,06408473 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01307797 0,06395448 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01307797 0,06382475 ! toxin metabolic process GO:0009404 11 6 0,000 0,01307797 0,06369555 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01307797 0,06356687 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01307797 0,06343871 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01307797 0,06331107 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01307797 0,06318394 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01307797 0,06305732 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01307797 0,06293121 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01307797 0,06280559 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01307797 0,06268048 ! thymic T cell selection GO:0045061 12 6 0,000 0,01307797 0,06255587 ! protein lipoylation GO:0009249 10 6 0,000 0,01307797 0,06243175 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01307797 0,06230812 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01307797 0,06218499 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01307797 0,06206233 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01307797 0,06194016 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01307797 0,06181847 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01307797 0,06169726 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01307797 0,06157652 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01307797 0,06145626 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01307797 0,06133646 ! hyperosmotic response GO:0006972 9 6 0,000 0,01307797 0,06121713 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01307797 0,06109826 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01307797 0,06097985 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01307797 0,0608619 ! urea metabolic process GO:0019627 7 6 0,000 0,01307797 0,06074441 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01307797 0,06062737 ! neutrophil activation GO:0042119 8 6 0,000 0,01307797 0,06051077 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01307797 0,06039463 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01307797 0,06027893 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01307797 0,06016368 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01307797 0,06004886 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01307797 0,05993448 ! neuron apoptosis GO:0051402 9 6 0,000 0,01307797 0,05982054 ! nucleoside salvage GO:0043174 9 6 0,000 0,01307797 0,05970703 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01307797 0,05959394 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01307797 0,05948129 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01307797 0,05936906 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01307797 0,05925726 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01307797 0,05914587 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01307797 0,0590349 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01307797 0,05892435 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01307797 0,05881421 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01307797 0,05870448 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01307797 0,05859516 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01307797 0,05848625 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01307797 0,05837774 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01307797 0,05826963 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01307797 0,05816193 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01307797 0,05805462 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01307797 0,0579477 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01307797 0,05784118 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01307797 0,05773505 ! neural nucleus development GO:0048857 14 6 0,000 0,01307797 0,05762931 ! response to UV-C GO:0010225 11 6 0,000 0,01307797 0,05752395 ! astrocyte development GO:0014002 15 6 0,000 0,01307797 0,05741898 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01307797 0,05731439 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01307797 0,05721019 ! interaction with symbiont GO:0051702 13 6 0,000 0,01307797 0,05710636 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01307797 0,0570029 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01307797 0,05689982 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01307797 0,05679712 ! response to copper ion GO:0046688 10 6 0,000 0,01307797 0,05669478 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01307797 0,05659281 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01307797 0,05649121 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01307797 0,05638997 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01307797 0,05628909 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01307797 0,05618858 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01307797 0,05608842 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01307797 0,05598862 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01307797 0,05588917 ! hair follicle maturation GO:0048820 7 6 0,000 0,01307797 0,05579008 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01307797 0,05569133 ! Schwann cell development GO:0014044 15 6 0,000 0,01307797 0,05559294 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01307797 0,05549489 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01307797 0,05539719 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01307797 0,05529983 ! subpallium development GO:0021544 10 6 0,000 0,01307797 0,05520281 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01307797 0,05510613 ! histone ubiquitination GO:0016574 8 6 0,000 0,01307797 0,05500979 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01307797 0,05491379 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01307797 0,05481812 ! G2 phase GO:0051319 16 6 0,000 0,01307797 0,05472279 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01307797 0,05462778 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01307797 0,05453311 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01307797 0,05443876 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01307797 0,05434474 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01307797 0,05425104 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01307797 0,05415766 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01307797 0,05406461 ! receptor internalization GO:0031623 10 6 0,000 0,01307797 0,05397187 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01307797 0,05387946 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01307797 0,05378735 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01307797 0,05369557 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01307797 0,05360409 ! protein deubiquitination GO:0016579 14 6 0,000 0,01307797 0,05351293 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01307797 0,05342208 ! protein destabilization GO:0031648 9 6 0,000 0,01307797 0,05333153 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01307797 0,05324129 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01307797 0,05315136 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01307797 0,05306172 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01307797 0,05297239 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01307797 0,05288337 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01307797 0,05279464 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01307797 0,0527062 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01307797 0,05261806 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01307797 0,05253022 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01307797 0,05244267 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01307797 0,05235541 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01307797 0,05226844 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01307797 0,05218176 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01307797 0,05209537 ! catecholamine transport GO:0051937 9 6 0,000 0,01307797 0,05200926 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01307797 0,05192344 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01307797 0,0518379 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01307797 0,05175264 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01307797 0,05166766 ! maternal placenta development GO:0001893 12 6 0,000 0,01307797 0,05158296 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01307797 0,05149853 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01307797 0,05141438 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01307797 0,05133051 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01307797 0,05124691 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01307797 0,05116358 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01307797 0,05108052 ! protein import into nucleus GO:0006606 158 80 1,000 0,01339038 0,05221598 ! T cell activation GO:0042110 168 81 1,000 0,01371016 0,05337646 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01371016 0,05329023 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01371016 0,05320428 ! nuclear import GO:0051170 161 81 1,000 0,01371016 0,0531186 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,01403325 0,05428296 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,01403325 0,05419583 ! response to oxygen levels GO:0070482 176 83 1,000 0,01435963 0,05536742 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,01468929 0,05654788 ! hemostasis GO:0007599 158 84 1,000 0,01468929 0,05645755 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0150222 0,05764501 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 14 7 0,000 0,0152412 0,05839223 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0152412 0,0582994 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0152412 0,05820686 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0152412 0,05811461 ! regulation of helicase activity GO:0051095 15 7 0,000 0,0152412 0,05802266 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0152412 0,057931 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0152412 0,05783962 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0152412 0,05774854 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0152412 0,05765774 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0152412 0,05756722 ! prostate gland development GO:0030850 13 7 0,000 0,0152412 0,05747699 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0152412 0,05738704 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0152412 0,05729738 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0152412 0,05720799 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0152412 0,05711888 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0152412 0,05703005 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0152412 0,05694149 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0152412 0,05685321 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,0152412 0,0567652 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0152412 0,05667747 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0152412 0,05659 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0152412 0,05650281 ! glycolipid transport GO:0046836 10 7 0,000 0,0152412 0,05641588 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0152412 0,05632922 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,0152412 0,05624282 ! neuron adhesion GO:0007158 12 7 0,000 0,0152412 0,05615669 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,0152412 0,05607083 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0152412 0,05598522 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0152412 0,05589988 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0152412 0,0558148 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0152412 0,05572997 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0152412 0,0556454 ! mRNA stabilization GO:0048255 18 7 0,000 0,0152412 0,05556109 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,0152412 0,05547704 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0152412 0,05539323 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0152412 0,05530968 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0152412 0,05522639 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0152412 0,05514334 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0152412 0,05506054 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0152412 0,05497799 ! lipoprotein transport GO:0042953 14 7 0,000 0,0152412 0,05489569 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0152412 0,05481363 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0152412 0,05473182 ! rhythmic behavior GO:0007622 15 7 0,000 0,0152412 0,05465025 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0152412 0,05456893 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0152412 0,05448785 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0152412 0,054407 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0152412 0,0543264 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0152412 0,05424604 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0152412 0,05416591 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0152412 0,05408602 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0152412 0,05400636 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0152412 0,05392694 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0152412 0,05384775 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0152412 0,0537688 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0152412 0,05369007 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0152412 0,05361158 ! spinal cord patterning GO:0021511 13 7 0,000 0,0152412 0,05353332 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0152412 0,05345528 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0152412 0,05337747 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0152412 0,05329988 ! adrenal gland development GO:0030325 17 7 0,000 0,0152412 0,05322253 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0152412 0,05314539 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0152412 0,05306848 ! ovulation GO:0030728 9 7 0,000 0,0152412 0,05299179 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0152412 0,05291533 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0152412 0,05283908 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,0152412 0,05276305 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0152412 0,05268724 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0152412 0,05261165 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0152412 0,05253628 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0152412 0,05246112 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0152412 0,05238617 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0152412 0,05231144 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0152412 0,05223692 ! galactose metabolic process GO:0006012 13 7 0,000 0,0152412 0,05216262 ! response to dietary excess GO:0002021 8 7 0,000 0,0152412 0,05208852 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0152412 0,05201464 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0152412 0,05194096 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0152412 0,0518675 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0152412 0,05179424 ! organ growth GO:0035265 15 7 0,000 0,0152412 0,05172119 ! purine salvage GO:0043101 10 7 0,000 0,0152412 0,05164834 ! nucleoside transport GO:0015858 8 7 0,000 0,0152412 0,0515757 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0152412 0,05150326 ! parturition GO:0007567 14 7 0,000 0,0152412 0,05143102 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0152412 0,05135899 ! rRNA modification GO:0000154 14 7 0,000 0,0152412 0,05128716 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0152412 0,05121553 ! spindle checkpoint GO:0031577 15 7 0,000 0,0152412 0,0511441 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0152412 0,05107287 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0152412 0,05100184 ! macrophage differentiation GO:0030225 11 7 0,000 0,0152412 0,050931 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0152412 0,05086036 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0152412 0,05078992 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0152412 0,05071967 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0152412 0,05064961 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,0152412 0,05057975 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0152412 0,05051008 ! fibrinolysis GO:0042730 10 7 0,000 0,0152412 0,05044061 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0152412 0,05037132 ! eating behavior GO:0042755 7 7 0,000 0,0152412 0,05030222 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0152412 0,05023332 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0152412 0,0501646 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0152412 0,05009607 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0152412 0,05002772 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0152412 0,04995957 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0152412 0,04989159 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0152412 0,04982381 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0152412 0,0497562 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0152412 0,04968878 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0152412 0,04962154 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0152412 0,04955449 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0152412 0,04948761 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0152412 0,04942092 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,0152412 0,0493544 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0152412 0,04928807 ! regulation of meiosis GO:0040020 12 7 0,000 0,0152412 0,04922191 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0152412 0,04915593 ! T cell lineage commitment GO:0002360 16 7 0,000 0,0152412 0,04909012 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0152412 0,04902449 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0152412 0,04895904 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0152412 0,04889376 ! transcription termination GO:0006353 13 7 0,000 0,0152412 0,04882866 ! response to tumor cell GO:0002347 13 7 0,000 0,0152412 0,04876372 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,0152412 0,04869897 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0152412 0,04863438 ! anaphase GO:0051322 17 7 0,000 0,0152412 0,04856996 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0152412 0,04850572 ! axonal fasciculation GO:0007413 18 7 0,000 0,0152412 0,04844164 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0152412 0,04837773 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0152412 0,04831399 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0152412 0,04825042 ! diuresis GO:0030146 12 7 0,000 0,0152412 0,04818702 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0152412 0,04812378 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0152412 0,04806071 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0152412 0,0479978 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0152412 0,04793506 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0152412 0,04787248 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0152412 0,04781007 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0152412 0,04774781 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0152412 0,04768572 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0152412 0,04762379 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0152412 0,04756202 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0152412 0,04750042 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0152412 0,04743897 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0152412 0,04737768 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0152412 0,04731654 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0152412 0,04725557 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0152412 0,04719475 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0152412 0,04713409 ! adult feeding behavior GO:0008343 9 7 0,000 0,0152412 0,04707358 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0152412 0,04701323 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0152412 0,04695304 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0152412 0,04689299 ! muscle adaptation GO:0043500 14 7 0,000 0,0152412 0,0468331 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0152412 0,04677337 ! retina homeostasis GO:0001895 12 7 0,000 0,0152412 0,04671378 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0152412 0,04665435 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0152412 0,04659507 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0152412 0,04653594 ! protein prenylation GO:0018342 18 7 0,000 0,0152412 0,04647696 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0152412 0,04641813 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,01569776 0,04774818 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,01569776 0,04768789 ! regulation of protein transport GO:0051223 154 87 1,000 0,01569776 0,04762775 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 1,000 0,01604037 0,04860594 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,01673516 0,05064755 ! sex differentiation GO:0007548 145 90 1,000 0,01673516 0,05058392 ! sterol metabolic process GO:0016125 152 91 1,000 0,01708732 0,05158356 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01739975 0,05246091 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01739975 0,05239525 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01739975 0,05232975 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01739975 0,05226442 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01739975 0,05219926 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01739975 0,05213425 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01739975 0,05206941 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01739975 0,05200472 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01739975 0,0519402 ! meiotic prophase I GO:0007128 13 8 0,000 0,01739975 0,05187584 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01739975 0,05181164 ! oligopeptide transport GO:0006857 15 8 0,000 0,01739975 0,05174759 ! UTP metabolic process GO:0046051 8 8 0,000 0,01739975 0,05168371 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01739975 0,05161998 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01739975 0,05155641 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01739975 0,05149299 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01739975 0,05142973 ! succinate metabolic process GO:0006105 14 8 0,000 0,01739975 0,05136663 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01739975 0,05130368 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01739975 0,05124089 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01739975 0,05117824 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01739975 0,05111575 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01739975 0,05105342 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01739975 0,05099123 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01739975 0,0509292 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01739975 0,05086732 ! reflex GO:0060004 16 8 0,000 0,01739975 0,05080559 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01739975 0,050744 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01739975 0,05068257 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01739975 0,05062129 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01739975 0,05056015 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01739975 0,05049916 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01739975 0,05043832 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01739975 0,05037762 ! pigment granule organization GO:0048753 16 8 0,000 0,01739975 0,05031707 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01739975 0,05025667 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01739975 0,05019641 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01739975 0,05013629 ! histidine metabolic process GO:0006547 16 8 0,000 0,01739975 0,05007632 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01739975 0,05001649 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01739975 0,04995681 ! glycine catabolic process GO:0006546 13 8 0,000 0,01739975 0,04989726 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01739975 0,04983786 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01739975 0,0497786 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01739975 0,04971948 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01739975 0,0496605 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01739975 0,04960166 ! melanin metabolic process GO:0006582 15 8 0,000 0,01739975 0,04954296 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01739975 0,0494844 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01739975 0,04942598 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01739975 0,04936769 ! macrophage activation GO:0042116 12 8 0,000 0,01739975 0,04930954 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01739975 0,04925153 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01739975 0,04919366 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01739975 0,04913592 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01739975 0,04907832 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01739975 0,04902085 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01739975 0,04896351 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01739975 0,04890631 ! osteoblast development GO:0002076 16 8 0,000 0,01739975 0,04884925 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01739975 0,04879231 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01739975 0,04873551 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01739975 0,04867884 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01739975 0,0486223 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01739975 0,0485659 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01739975 0,04850962 ! response to UV-B GO:0010224 16 8 0,000 0,01739975 0,04845348 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01739975 0,04839746 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01739975 0,04834157 ! intermediate filament organization GO:0045109 12 8 0,000 0,01739975 0,04828582 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01739975 0,04823019 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01739975 0,04817469 ! cellular extravasation GO:0045123 12 8 0,000 0,01739975 0,04811931 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01739975 0,04806407 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01739975 0,04800895 ! response to antibiotic GO:0046677 11 8 0,000 0,01739975 0,04795396 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01739975 0,04789909 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01739975 0,04784435 ! DNA topological change GO:0006265 12 8 0,000 0,01739975 0,04778973 ! response to tropane GO:0014073 15 8 0,000 0,01739975 0,04773524 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01739975 0,04768087 ! melanosome transport GO:0032402 13 8 0,000 0,01739975 0,04762662 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01739975 0,0475725 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01739975 0,04751851 ! mast cell activation GO:0045576 14 8 0,000 0,01739975 0,04746463 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01739975 0,04741088 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01739975 0,04735724 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01739975 0,04730373 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01739975 0,04725034 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01739975 0,04719707 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01739975 0,04714392 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01739975 0,04709089 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01739975 0,04703798 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01739975 0,04698519 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01739975 0,04693251 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01739975 0,04687996 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01739975 0,04682752 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01739975 0,0467752 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01739975 0,04672299 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01739975 0,04667091 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01739975 0,04661893 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01739975 0,04656708 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01739975 0,04651534 ! hormone catabolic process GO:0042447 17 8 0,000 0,01739975 0,04646371 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01739975 0,0464122 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01739975 0,0463608 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01739975 0,04630952 ! ATP catabolic process GO:0006200 11 8 0,000 0,01739975 0,04625835 ! blastocyst growth GO:0001832 19 8 0,000 0,01739975 0,04620729 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01739975 0,04615634 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01739975 0,04610551 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01739975 0,04605479 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01739975 0,04600418 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01739975 0,04595368 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01739975 0,04590329 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01739975 0,04585302 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01739975 0,04580285 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01739975 0,04575279 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01739975 0,04570284 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01739975 0,045653 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01739975 0,04560327 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01739975 0,04555365 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01739975 0,04550413 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01739975 0,04545473 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01739975 0,04540543 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,01780109 0,04640241 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,01780109 0,04635219 ! regulation of membrane potential GO:0042391 164 93 1,000 0,01780109 0,04630208 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,01780109 0,04625207 ! regulation of T cell activation GO:0050863 158 94 1,000 0,01816267 0,04714064 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01852735 0,04803535 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,01852735 0,04798364 ! leukocyte differentiation GO:0002521 202 96 1,000 0,01889513 0,04888353 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,01926599 0,04978944 ! regulation of protein localization GO:0032880 176 97 1,000 0,01926599 0,04973602 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01955365 0,05042452 ! axon extension GO:0048675 15 9 0,000 0,01955365 0,05037053 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01955365 0,05031666 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01955365 0,0502629 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01955365 0,05020926 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01955365 0,05015573 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01955365 0,05010232 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01955365 0,05004901 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01955365 0,04999583 ! phosphate transport GO:0006817 19 9 0,000 0,01955365 0,04994275 ! reproductive behavior GO:0019098 19 9 0,000 0,01955365 0,04988979 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01955365 0,04983694 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01955365 0,04978421 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01955365 0,04973158 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01955365 0,04967906 ! GTP metabolic process GO:0046039 9 9 0,000 0,01955365 0,04962666 ! RNA methylation GO:0001510 15 9 0,000 0,01955365 0,04957437 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01955365 0,04952218 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01955365 0,04947011 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01955365 0,04941815 ! artery development GO:0060840 24 9 0,000 0,01955365 0,04936629 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01955365 0,04931454 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01955365 0,0492629 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01955365 0,04921137 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01955365 0,04915995 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01955365 0,04910864 ! chemosensory behavior GO:0007635 20 9 0,000 0,01955365 0,04905743 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01955365 0,04900633 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01955365 0,04895533 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01955365 0,04890444 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01955365 0,04885366 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01955365 0,04880298 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01955365 0,04875241 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01955365 0,04870194 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01955365 0,04865158 ! protein targeting to ER GO:0045047 22 9 0,000 0,01955365 0,04860132 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01955365 0,04855116 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01955365 0,04850111 ! T cell selection GO:0045058 23 9 0,000 0,01955365 0,04845116 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01955365 0,04840131 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01955365 0,04835157 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01955365 0,04830192 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01955365 0,04825238 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01955365 0,04820294 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01955365 0,04815361 ! mannose metabolic process GO:0006013 13 9 0,000 0,01955365 0,04810437 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01955365 0,04805523 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01955365 0,0480062 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01955365 0,04795726 ! receptor clustering GO:0043113 18 9 0,000 0,01955365 0,04790843 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01955365 0,04785969 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01955365 0,04781105 ! ruffle organization GO:0031529 15 9 0,000 0,01955365 0,04776251 ! retinol metabolic process GO:0042572 18 9 0,000 0,01955365 0,04771407 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01955365 0,04766573 ! behavioral fear response GO:0001662 22 9 0,000 0,01955365 0,04761748 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01955365 0,04756934 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01955365 0,04752129 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01955365 0,04747333 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01955365 0,04742548 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01955365 0,04737772 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01955365 0,04733005 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01955365 0,04728249 ! segment specification GO:0007379 13 9 0,000 0,01955365 0,04723501 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01955365 0,04718764 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01955365 0,04714035 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01955365 0,04709317 ! response to amine stimulus GO:0014075 13 9 0,000 0,01955365 0,04704607 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01955365 0,04699907 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01955365 0,04695217 ! erythrocyte development GO:0048821 15 9 0,000 0,01955365 0,04690536 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01955365 0,04685864 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01955365 0,04681201 ! renal water homeostasis GO:0003091 14 9 0,000 0,01955365 0,04676548 ! postreplication repair GO:0006301 22 9 0,000 0,01955365 0,04671904 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01955365 0,04667269 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01955365 0,04662644 ! icosanoid secretion GO:0032309 15 9 0,000 0,01955365 0,04658027 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01955365 0,0465342 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01955365 0,04648822 ! regulation of cell division GO:0051302 15 9 0,000 0,01955365 0,04644232 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01955365 0,04639652 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01955365 0,04635081 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01955365 0,04630519 ! sterol catabolic process GO:0016127 11 9 0,000 0,01955365 0,04625966 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01955365 0,04621422 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01955365 0,04616887 ! S phase GO:0051320 9 9 0,000 0,01955365 0,0461236 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01955365 0,04607843 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01955365 0,04603334 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01955365 0,04598834 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01955365 0,04594343 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01955365 0,04589861 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01955365 0,04585387 ! purine base metabolic process GO:0006144 21 9 0,000 0,01955365 0,04580922 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01955365 0,04576466 ! pigment granule transport GO:0051904 17 9 0,000 0,01955365 0,04572019 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01955365 0,0456758 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01955365 0,0456315 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01955365 0,04558728 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01955365 0,04554315 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01955365 0,0454991 ! mitochondrion localization GO:0051646 15 9 0,000 0,01955365 0,04545514 ! interphase GO:0051325 213 98 1,000 0,01963991 0,04561161 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02170289 0,05035406 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02170289 0,05030555 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02170289 0,05025713 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02170289 0,0502088 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02170289 0,05016057 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02170289 0,05011243 ! synapsis GO:0007129 13 10 0,000 0,02170289 0,05006439 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02170289 0,05001643 ! N-glycan processing GO:0006491 20 10 0,000 0,02170289 0,04996857 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02170289 0,0499208 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02170289 0,04987312 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02170289 0,04982553 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02170289 0,04977803 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02170289 0,04973063 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02170289 0,04968331 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02170289 0,04963608 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02170289 0,04958894 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02170289 0,04954189 ! androgen metabolic process GO:0008209 17 10 0,000 0,02170289 0,04949494 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02170289 0,04944807 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02170289 0,04940128 ! lung alveolus development GO:0048286 26 10 0,000 0,02170289 0,04935459 ! pathogenesis GO:0009405 13 10 0,000 0,02170289 0,04930799 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02170289 0,04926147 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02170289 0,04921504 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02170289 0,0491687 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02170289 0,04912244 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02170289 0,04907628 ! endoderm development GO:0007492 16 10 0,000 0,02170289 0,04903019 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02170289 0,0489842 ! arginine catabolic process GO:0006527 13 10 0,000 0,02170289 0,04893829 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02170289 0,04889247 ! proline metabolic process GO:0006560 13 10 0,000 0,02170289 0,04884673 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02170289 0,04880108 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02170289 0,04875552 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02170289 0,04871003 ! V(D)J recombination GO:0033151 28 10 0,000 0,02170289 0,04866464 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02170289 0,04861933 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02170289 0,0485741 ! B cell proliferation GO:0042100 18 10 0,000 0,02170289 0,04852896 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02170289 0,0484839 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02170289 0,04843892 ! multicellular organism growth GO:0035264 18 10 0,000 0,02170289 0,04839403 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02170289 0,04834922 ! epithelial cell development GO:0002064 20 10 0,000 0,02170289 0,04830449 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02170289 0,04825985 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02170289 0,04821529 ! macroautophagy GO:0016236 17 10 0,000 0,02170289 0,04817081 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02170289 0,04812641 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02170289 0,0480821 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02170289 0,04803786 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02170289 0,04799371 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02170289 0,04794964 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02170289 0,04790565 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02170289 0,04786174 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02170289 0,04781791 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02170289 0,04777416 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02170289 0,04773049 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02170289 0,0476869 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02170289 0,04764339 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02170289 0,04759996 ! response to dsRNA GO:0043331 20 10 0,000 0,02170289 0,04755661 ! DNA ligation GO:0006266 19 10 0,000 0,02170289 0,04751334 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02170289 0,04747014 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02170289 0,04742703 ! melanosome localization GO:0032400 16 10 0,000 0,02170289 0,04738399 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02170289 0,04734103 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02170289 0,04729815 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02170289 0,04725535 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02170289 0,04721262 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02170289 0,04716997 ! mRNA cleavage GO:0006379 17 10 0,000 0,02170289 0,0471274 ! protein sumoylation GO:0016925 15 10 0,000 0,02170289 0,0470849 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02170289 0,04704248 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02170289 0,04700014 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02170289 0,04695787 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02170289 0,04691568 ! salivary gland development GO:0007431 27 10 0,000 0,02170289 0,04687357 ! prophase GO:0051324 15 10 0,000 0,02170289 0,04683153 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02170289 0,04678957 ! apical protein localization GO:0045176 15 10 0,000 0,02170289 0,04674768 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02170289 0,04670586 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02170289 0,04666413 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02170289 0,04662246 ! midbrain development GO:0030901 13 10 0,000 0,02170289 0,04658087 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02170289 0,04653936 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02170289 0,04649791 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02170289 0,04645655 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02170289 0,04641525 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02170289 0,04637403 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02170289 0,04633288 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02170289 0,04629181 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02170289 0,0462508 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02170289 0,04620987 ! oocyte development GO:0048599 17 10 0,000 0,02170289 0,04616902 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02170289 0,04612823 ! blastocyst formation GO:0001825 17 10 0,000 0,02170289 0,04608752 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02170289 0,04604688 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02170289 0,04600631 ! activation of innate immune response GO:0002218 12 10 0,000 0,02170289 0,04596581 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02170289 0,04592538 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02170289 0,04588502 ! response to nicotine GO:0035094 20 10 0,000 0,02170289 0,04584474 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02170289 0,04580452 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0238475 0,05028666 ! respiratory burst GO:0045730 17 11 0,000 0,0238475 0,05024262 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0238475 0,05019867 ! neuron fate specification GO:0048665 17 11 0,000 0,0238475 0,05015479 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0238475 0,05011098 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0238475 0,05006726 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0238475 0,05002361 ! thyroid gland development GO:0030878 26 11 0,000 0,0238475 0,04998003 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0238475 0,04993653 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0238475 0,04989311 ! response to pain GO:0048265 24 11 0,000 0,0238475 0,04984976 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0238475 0,04980649 ! T cell proliferation GO:0042098 26 11 0,000 0,0238475 0,04976329 ! blood vessel remodeling GO:0001974 29 11 0,000 0,0238475 0,04972017 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0238475 0,04967712 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,0238475 0,04963415 ! bone resorption GO:0045453 16 11 0,000 0,0238475 0,04959125 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,0238475 0,04954842 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0238475 0,04950567 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0238475 0,049463 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0238475 0,04942039 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0238475 0,04937786 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0238475 0,0493354 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0238475 0,04929302 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0238475 0,04925071 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0238475 0,04920847 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0238475 0,0491663 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,0238475 0,04912421 ! lipid digestion GO:0044241 18 11 0,000 0,0238475 0,04908219 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0238475 0,04904024 ! UV protection GO:0009650 19 11 0,000 0,0238475 0,04899836 ! adult heart development GO:0007512 14 11 0,000 0,0238475 0,04895655 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0238475 0,04891481 ! temperature homeostasis GO:0001659 17 11 0,000 0,0238475 0,04887315 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0238475 0,04883155 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0238475 0,04879003 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0238475 0,04874858 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0238475 0,04870719 ! regulation of organ growth GO:0046620 13 11 0,000 0,0238475 0,04866588 ! pigment granule localization GO:0051875 20 11 0,000 0,0238475 0,04862464 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0238475 0,04858347 ! vasoconstriction GO:0042310 18 11 0,000 0,0238475 0,04854236 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0238475 0,04850133 ! embryonic axis specification GO:0000578 18 11 0,000 0,0238475 0,04846037 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0238475 0,04841947 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0238475 0,04837865 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0238475 0,04833789 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0238475 0,0482972 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0238475 0,04825658 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0238475 0,04821603 ! zymogen activation GO:0031638 15 11 0,000 0,0238475 0,04817555 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0238475 0,04813513 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0238475 0,04809478 ! nucleosome positioning GO:0016584 15 11 0,000 0,0238475 0,0480545 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0238475 0,04801429 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0238475 0,04797414 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0238475 0,04793406 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,0238475 0,04789405 ! acid secretion GO:0046717 18 11 0,000 0,0238475 0,04785411 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0238475 0,04781423 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0238475 0,04777442 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0238475 0,04773467 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0238475 0,04769499 ! oocyte differentiation GO:0009994 18 11 0,000 0,0238475 0,04765538 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0238475 0,04761583 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0238475 0,04757635 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0238475 0,04753693 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0238475 0,04749758 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0238475 0,04745829 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0238475 0,04741907 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0238475 0,04737991 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0238475 0,04734082 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0238475 0,04730179 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0238475 0,04726283 ! defense response to fungus GO:0050832 13 11 0,000 0,0238475 0,04722393 ! lysogeny GO:0030069 21 11 0,000 0,0238475 0,04718509 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0238475 0,04714632 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0238475 0,04710762 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0238475 0,04706897 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0238475 0,04703039 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0238475 0,04699187 ! nucleus localization GO:0051647 19 11 0,000 0,0238475 0,04695342 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0238475 0,04691502 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02598747 0,05108321 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02598747 0,05104151 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02598747 0,05099988 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02598747 0,05095832 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02598747 0,05091682 ! virus-host interaction GO:0019048 29 12 0,000 0,02598747 0,05087539 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02598747 0,05083403 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02598747 0,05079273 ! cartilage condensation GO:0001502 20 12 0,000 0,02598747 0,0507515 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02598747 0,05071034 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02598747 0,05066925 ! protein complex disassembly GO:0043241 27 12 0,000 0,02598747 0,05062822 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02598747 0,05058726 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02598747 0,05054636 ! hippocampus development GO:0021766 26 12 0,000 0,02598747 0,05050554 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02598747 0,05046477 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02598747 0,05042408 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02598747 0,05038344 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02598747 0,05034288 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02598747 0,05030238 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02598747 0,05026194 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02598747 0,05022157 ! drug transport GO:0015893 16 12 0,000 0,02598747 0,05018126 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02598747 0,05014102 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02598747 0,05010084 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02598747 0,05006073 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02598747 0,05002068 ! focal adhesion formation GO:0048041 35 12 0,000 0,02598747 0,0499807 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02598747 0,04994078 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02598747 0,04990092 ! forebrain cell migration GO:0021885 21 12 0,000 0,02598747 0,04986113 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02598747 0,0498214 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02598747 0,04978173 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02598747 0,04974213 ! entry into host cell GO:0030260 32 12 0,000 0,02598747 0,04970259 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02598747 0,04966311 ! monoamine transport GO:0015844 18 12 0,000 0,02598747 0,04962369 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02598747 0,04958434 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02598747 0,04954505 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02598747 0,04950582 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02598747 0,04946666 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02598747 0,04942755 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02598747 0,04938851 ! protein homotetramerization GO:0051289 21 12 0,000 0,02598747 0,04934953 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02598747 0,04931061 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02598747 0,04927175 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02598747 0,04923296 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02598747 0,04919422 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02598747 0,04915555 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02598747 0,04911693 ! cranial nerve development GO:0021545 20 12 0,000 0,02598747 0,04907838 ! fucose catabolic process GO:0019317 22 12 0,000 0,02598747 0,04903989 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02598747 0,04900145 ! histone acetylation GO:0016573 26 12 0,000 0,02598747 0,04896308 ! histone methylation GO:0016571 26 12 0,000 0,02598747 0,04892477 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02598747 0,04888652 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02598747 0,04884832 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02598747 0,04881019 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02598747 0,04877212 ! T cell homeostasis GO:0043029 25 12 0,000 0,02598747 0,0487341 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02598747 0,04869615 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02598747 0,04865825 ! spleen development GO:0048536 22 12 0,000 0,02598747 0,04862041 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02598747 0,04858264 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02598747 0,04854492 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02598747 0,04850726 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02598747 0,04846965 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02598747 0,04843211 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02598747 0,04839462 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02598747 0,0483572 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02598747 0,04831982 ! response to cold GO:0009409 17 12 0,000 0,02598747 0,04828251 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02598747 0,04824526 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02598747 0,04820806 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02812282 0,05212906 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02812282 0,05208893 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02812282 0,05204886 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02812282 0,05200885 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02812282 0,05196891 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02812282 0,05192902 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02812282 0,0518892 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02812282 0,05184944 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02812282 0,05180974 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02812282 0,0517701 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02812282 0,05173052 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02812282 0,051691 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02812282 0,05165154 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02812282 0,05161214 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02812282 0,0515728 ! methionine metabolic process GO:0006555 27 13 0,000 0,02812282 0,05153352 ! plasma membrane organization GO:0007009 24 13 0,000 0,02812282 0,0514943 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02812282 0,05145514 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02812282 0,05141604 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02812282 0,051377 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02812282 0,05133802 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02812282 0,0512991 ! response to X-ray GO:0010165 25 13 0,000 0,02812282 0,05126024 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02812282 0,05122143 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02812282 0,05118269 ! exocrine system development GO:0035272 32 13 0,000 0,02812282 0,051144 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02812282 0,05110537 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02812282 0,0510668 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02812282 0,05102829 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02812282 0,05098984 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02812282 0,05095144 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02812282 0,0509131 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02812282 0,05087482 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02812282 0,0508366 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02812282 0,05079843 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02812282 0,05076033 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02812282 0,05072227 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02812282 0,05068428 ! ribosome assembly GO:0042255 17 13 0,000 0,02812282 0,05064634 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02812282 0,05060846 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02812282 0,05057064 ! chromatin silencing GO:0006342 26 13 0,000 0,02812282 0,05053287 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02812282 0,05049516 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02812282 0,05045751 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02812282 0,05041991 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02812282 0,05038236 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02812282 0,05034488 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02812282 0,05030745 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02812282 0,05027007 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02812282 0,05023275 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02812282 0,05019549 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02812282 0,05015828 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02812282 0,05012112 ! embryonic placenta development GO:0001892 23 13 0,000 0,02812282 0,05008402 ! insulin secretion GO:0030073 23 13 0,000 0,02812282 0,05004698 ! actin filament polymerization GO:0030041 24 13 0,000 0,02812282 0,05000999 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02812282 0,04997305 ! acrosome reaction GO:0007340 18 13 0,000 0,02812282 0,04993617 ! rRNA transcription GO:0009303 25 14 0,000 0,03025357 0,05368 ! lactation GO:0007595 26 14 0,000 0,03025357 0,05364044 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03025357 0,05360094 ! reproductive cellular process GO:0048610 20 14 0,000 0,03025357 0,0535615 ! tRNA modification GO:0006400 20 14 0,000 0,03025357 0,05352212 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03025357 0,05348279 ! regulation of S phase GO:0033261 23 14 0,000 0,03025357 0,05344353 ! water transport GO:0006833 21 14 0,000 0,03025357 0,05340432 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03025357 0,05336516 ! non-recombinational repair GO:0000726 25 14 0,000 0,03025357 0,05332607 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03025357 0,05328703 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03025357 0,05324805 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03025357 0,05320912 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03025357 0,05317026 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03025357 0,05313145 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03025357 0,05309269 ! palate development GO:0060021 31 14 0,000 0,03025357 0,053054 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03025357 0,05301536 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03025357 0,05297677 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03025357 0,05293824 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03025357 0,05289977 ! arginine metabolic process GO:0006525 17 14 0,000 0,03025357 0,05286135 ! regulation of heart rate GO:0002027 24 14 0,000 0,03025357 0,05282299 ! organic alcohol transport GO:0015850 29 14 0,000 0,03025357 0,05278469 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03025357 0,05274644 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03025357 0,05270824 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03025357 0,0526701 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03025357 0,05263202 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03025357 0,05259399 ! L-amino acid transport GO:0015807 30 14 0,000 0,03025357 0,05255602 ! bone mineralization GO:0030282 17 14 0,000 0,03025357 0,0525181 ! stem cell development GO:0048864 43 14 0,000 0,03025357 0,05248023 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03025357 0,05244242 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03025357 0,05240467 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03025357 0,05236697 ! cerebellum development GO:0021549 21 14 0,000 0,03025357 0,05232932 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03025357 0,05229173 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03025357 0,05225419 ! response to gamma radiation GO:0010332 28 14 0,000 0,03025357 0,0522167 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03025357 0,05217927 ! cofactor transport GO:0051181 26 14 0,000 0,03025357 0,05214189 ! NADP metabolic process GO:0006739 24 14 0,000 0,03025357 0,05210457 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03025357 0,0520673 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03025357 0,05203008 ! intestinal absorption GO:0050892 25 14 0,000 0,03025357 0,05199292 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03025357 0,05195581 ! oxygen transport GO:0015671 21 14 0,000 0,03025357 0,05191875 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03025357 0,05188174 ! male genitalia development GO:0030539 24 14 0,000 0,03025357 0,05184479 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03025357 0,05180789 ! regulation of axon extension GO:0030516 37 14 0,000 0,03025357 0,05177104 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03025357 0,05173425 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03025357 0,0516975 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03237971 0,0552914 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03237971 0,05525219 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03237971 0,05521303 ! superoxide anion generation GO:0042554 20 15 0,000 0,03237971 0,05517392 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03237971 0,05513488 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03237971 0,05509589 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03237971 0,05505695 ! copper ion transport GO:0006825 20 15 0,000 0,03237971 0,05501807 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03237971 0,05497924 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03237971 0,05494047 ! sulfate transport GO:0008272 23 15 0,000 0,03237971 0,05490175 ! response to cAMP GO:0051591 22 15 0,000 0,03237971 0,05486309 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03237971 0,05482448 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03237971 0,05478592 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03237971 0,05474742 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03237971 0,05470898 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03237971 0,05467058 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03237971 0,05463225 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03237971 0,05459396 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03237971 0,05455573 ! pituitary gland development GO:0021983 29 15 0,000 0,03237971 0,05451755 ! vesicle coating GO:0006901 33 15 0,000 0,03237971 0,05447943 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03237971 0,05444136 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03237971 0,05440334 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03237971 0,05436537 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03237971 0,05432746 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03237971 0,0542896 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03237971 0,0542518 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03237971 0,05421404 ! histone deacetylation GO:0016575 20 15 0,000 0,03237971 0,05417634 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03237971 0,05413869 ! tissue regeneration GO:0042246 26 15 0,000 0,03237971 0,0541011 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03237971 0,05406355 ! water homeostasis GO:0030104 27 15 0,000 0,03237971 0,05402606 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03237971 0,05398862 ! muscle maintenance GO:0046716 26 15 0,000 0,03237971 0,05395123 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03237971 0,0539139 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03237971 0,05387661 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03237971 0,05383938 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03237971 0,0538022 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03237971 0,05376507 ! cell killing GO:0001906 29 15 0,000 0,03237971 0,05372799 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03237971 0,05369096 ! detection of bacterium GO:0016045 18 15 0,000 0,03237971 0,05365398 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03237971 0,05361706 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03237971 0,05358018 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03237971 0,05354335 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03237971 0,05350658 ! peptide hormone processing GO:0016486 23 15 0,000 0,03237971 0,05346986 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03450126 0,05693418 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03450126 0,05689516 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03450126 0,05685619 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03450126 0,05681727 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03450126 0,05677841 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03450126 0,0567396 ! bone remodeling GO:0046849 27 16 0,000 0,03450126 0,05670084 ! filopodium assembly GO:0046847 32 16 0,000 0,03450126 0,05666214 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03450126 0,05662349 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03450126 0,05658489 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03450126 0,05654634 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03450126 0,05650785 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03450126 0,05646941 ! startle response GO:0001964 28 16 0,000 0,03450126 0,05643102 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03450126 0,05639269 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03450126 0,0563544 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03450126 0,05631617 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03450126 0,05627799 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03450126 0,05623986 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03450126 0,05620178 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03450126 0,05616376 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03450126 0,05612578 ! response to osmotic stress GO:0006970 25 16 0,000 0,03450126 0,05608786 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03450126 0,05604999 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03450126 0,05601217 ! fructose metabolic process GO:0006000 25 16 0,000 0,03450126 0,0559744 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03450126 0,05593668 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03450126 0,05589901 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03450126 0,0558614 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03450126 0,05582383 ! axon cargo transport GO:0008088 43 16 0,000 0,03450126 0,05578631 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03450126 0,05574885 ! DNA replication initiation GO:0006270 27 16 0,000 0,03450126 0,05571143 ! neuron recognition GO:0008038 35 16 0,000 0,03450126 0,05567407 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03450126 0,05563675 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03450126 0,05559949 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03450126 0,05556227 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03450126 0,05552511 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03450126 0,05548799 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03450126 0,05545092 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03450126 0,05541391 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03450126 0,05537694 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03450126 0,05534002 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03450126 0,05530315 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03450126 0,05526633 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03450126 0,05522956 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03450126 0,05519284 ! defense response to virus GO:0051607 37 16 0,000 0,03450126 0,05515617 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03661823 0,05850164 ! metencephalon development GO:0022037 30 17 0,000 0,03661823 0,05846282 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03661823 0,05842405 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03661823 0,05838533 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03661823 0,05834666 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03661823 0,05830805 ! signal complex assembly GO:0007172 41 17 0,000 0,03661823 0,05826949 ! endothelial cell migration GO:0043542 28 17 0,000 0,03661823 0,05823097 ! inositol metabolic process GO:0006020 28 17 0,000 0,03661823 0,05819251 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03661823 0,0581541 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03661823 0,05811574 ! glial cell development GO:0021782 27 17 0,000 0,03661823 0,05807743 ! limbic system development GO:0021761 36 17 0,000 0,03661823 0,05803917 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03661823 0,05800096 ! adult walking behavior GO:0007628 33 17 0,000 0,03661823 0,05796281 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03661823 0,0579247 ! heart looping GO:0001947 30 17 0,000 0,03661823 0,05788664 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03661823 0,05784863 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03661823 0,05781067 ! myoblast differentiation GO:0045445 45 17 0,000 0,03661823 0,05777276 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03661823 0,0577349 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03661823 0,0576971 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03661823 0,05765934 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03661823 0,05762162 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03661823 0,05758396 ! glycine metabolic process GO:0006544 28 17 0,000 0,03661823 0,05754635 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03661823 0,05750879 ! NAD metabolic process GO:0019674 29 17 0,000 0,03661823 0,05747127 ! membrane budding GO:0006900 37 17 0,000 0,03661823 0,05743381 ! DNA integration GO:0015074 29 17 0,000 0,03661823 0,05739639 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03661823 0,05735903 ! regulation of protein binding GO:0043393 33 17 0,000 0,03661823 0,05732171 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03661823 0,05728444 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03661823 0,05724722 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03661823 0,05721004 ! genitalia development GO:0048806 30 17 0,000 0,03661823 0,05717292 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03661823 0,05713584 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03661823 0,05709881 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03661823 0,05706183 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03661823 0,0570249 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03661823 0,05698801 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03661823 0,05695117 ! steroid catabolic process GO:0006706 31 17 0,000 0,03661823 0,05691438 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03661823 0,05687764 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03661823 0,05684094 ! gas transport GO:0015669 25 17 0,000 0,03661823 0,0568043 ! organic cation transport GO:0015695 31 17 0,000 0,03661823 0,0567677 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03661823 0,05673114 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03661823 0,05669464 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03661823 0,05665818 ! microspike assembly GO:0030035 36 17 0,000 0,03661823 0,05662176 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03661823 0,0565854 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03661823 0,05654908 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03873063 0,05977286 ! neuron maturation GO:0042551 42 18 0,000 0,03873063 0,05973455 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03873063 0,05969628 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03873063 0,05965806 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03873063 0,05961989 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03873063 0,05958177 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03873063 0,0595437 ! memory GO:0007613 31 18 0,000 0,03873063 0,05950568 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03873063 0,05946771 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03873063 0,05942978 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03873063 0,0593919 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03873063 0,05935407 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03873063 0,05931629 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03873063 0,05927856 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03873063 0,05924087 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03873063 0,05920324 ! response to retinoic acid GO:0032526 26 18 0,000 0,03873063 0,05916565 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03873063 0,05912811 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03873063 0,05909061 ! response to fungus GO:0009620 21 18 0,000 0,03873063 0,05905317 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03873063 0,05901577 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03873063 0,05897841 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03873063 0,05894111 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03873063 0,05890385 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03873063 0,05886664 ! vitamin transport GO:0051180 27 18 0,000 0,03873063 0,05882948 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03873063 0,05879236 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03873063 0,05875529 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03873063 0,05871827 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03873063 0,05868129 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03873063 0,05864436 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03873063 0,05860748 ! nerve development GO:0021675 28 18 0,000 0,03873063 0,05857064 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03873063 0,05853385 ! positive regulation of translation GO:0045727 30 19 0,000 0,04083847 0,0616807 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04083847 0,061642 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04083847 0,06160335 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04083847 0,06156476 ! skin development GO:0043588 36 19 0,000 0,04083847 0,06152621 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04083847 0,0614877 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04083847 0,06144925 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04083847 0,06141084 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04083847 0,06137249 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04083847 0,06133418 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04083847 0,06129591 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04083847 0,0612577 ! cerebral cortex development GO:0021987 36 19 0,000 0,04083847 0,06121953 ! pigmentation during development GO:0048066 41 19 0,000 0,04083847 0,06118141 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04083847 0,06114334 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04083847 0,06110532 ! heme metabolic process GO:0042168 36 19 0,000 0,04083847 0,06106734 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04083847 0,06102941 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04083847 0,06099153 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04083847 0,06095369 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04083847 0,0609159 ! peptide cross-linking GO:0018149 37 19 0,000 0,04083847 0,06087816 ! protein export from nucleus GO:0006611 36 19 0,000 0,04083847 0,06084046 ! heart process GO:0003015 30 19 0,000 0,04083847 0,06080282 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04083847 0,06076521 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04083847 0,06072766 ! visual learning GO:0008542 36 19 0,000 0,04083847 0,06069015 ! cellular pigmentation GO:0033059 36 19 0,000 0,04083847 0,06065269 ! G1 phase GO:0051318 40 19 0,000 0,04083847 0,06061527 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04083847 0,0605779 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04083847 0,06054057 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04083847 0,06050329 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04083847 0,06046606 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04083847 0,06042887 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04083847 0,06039173 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04083847 0,06035464 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04083847 0,06031759 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04083847 0,06028058 ! cilium assembly GO:0042384 37 19 0,000 0,04083847 0,06024362 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04083847 0,06020671 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04294175 0,06326874 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04294175 0,06323002 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04294175 0,06319135 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04294175 0,06315272 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04294175 0,06311414 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04294175 0,06307561 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04294175 0,06303713 ! response to vitamin GO:0033273 31 20 0,000 0,04294175 0,06299869 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04294175 0,0629603 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04294175 0,06292196 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04294175 0,06288366 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04294175 0,06284541 ! response to alkaloid GO:0043279 38 20 0,000 0,04294175 0,06280721 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04294175 0,06276905 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04294175 0,06273094 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04294175 0,06269287 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04294175 0,06265485 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04294175 0,06261688 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04294175 0,06257895 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04294175 0,06254107 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04294175 0,06250324 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04294175 0,06246545 ! body fluid secretion GO:0007589 31 20 0,000 0,04294175 0,06242771 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04294175 0,06239001 ! stem cell differentiation GO:0048863 53 20 0,000 0,04294175 0,06235236 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04294175 0,06231475 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04294175 0,06227719 ! sensory perception of pain GO:0019233 30 20 0,000 0,04294175 0,06223967 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04294175 0,0622022 ! diencephalon development GO:0021536 34 20 0,000 0,04294175 0,06216477 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04294175 0,06212739 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04294175 0,06209006 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04294175 0,06205276 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04294175 0,06201552 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04294175 0,06197832 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04294175 0,06194116 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04294175 0,06190405 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04294175 0,06186698 ! regulation of glucose import GO:0046324 29 20 0,000 0,04294175 0,06182995 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04294175 0,06179297 ! actin filament-based movement GO:0030048 43 20 0,000 0,04294175 0,06175604 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04294175 0,06171915 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04294175 0,0616823 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04294175 0,0616455 ! negative regulation of translation GO:0017148 29 20 0,000 0,04294175 0,06160874 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04294175 0,06157202 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04294175 0,06153535 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04504049 0,06450442 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04504049 0,06446605 ! hormone secretion GO:0046879 38 21 0,000 0,04504049 0,06442772 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04504049 0,06438944 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04504049 0,0643512 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04504049 0,06431301 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04504049 0,06427487 ! axis specification GO:0009798 38 21 0,000 0,04504049 0,06423677 ! ovarian follicle development GO:0001541 35 21 0,000 0,04504049 0,06419871 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04504049 0,0641607 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04504049 0,06412274 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04504049 0,06408482 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04504049 0,06404694 ! cell aging GO:0007569 44 21 0,000 0,04504049 0,06400911 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04504049 0,06397133 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04504049 0,06393359 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04504049 0,06389589 ! cytolysis GO:0019835 24 21 0,000 0,04504049 0,06385824 ! vasodilation GO:0042311 39 21 0,000 0,04504049 0,06382063 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04504049 0,06378306 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04504049 0,06374555 ! oogenesis GO:0048477 36 21 0,000 0,04504049 0,06370807 ! DNA modification GO:0006304 34 21 0,000 0,04504049 0,06367064 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04504049 0,06363325 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04504049 0,06359591 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04504049 0,06355861 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04504049 0,06352135 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04504049 0,06348414 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04504049 0,06344697 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04504049 0,06340985 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04504049 0,06337276 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04504049 0,06333573 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04504049 0,06329873 ! collagen catabolic process GO:0030574 28 21 0,000 0,04504049 0,06326178 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04504049 0,06322487 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,0471347 0,066126 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,0471347 0,06608747 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,0471347 0,06604898 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,0471347 0,06601053 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,0471347 0,06597213 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,0471347 0,06593378 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,0471347 0,06589546 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,0471347 0,0658572 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,0471347 0,06581898 ! regeneration GO:0031099 41 22 0,000 0,0471347 0,0657808 ! keratinization GO:0031424 28 22 0,000 0,0471347 0,06574266 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,0471347 0,06570457 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,0471347 0,06566653 ! sensory perception of taste GO:0050909 28 22 0,000 0,0471347 0,06562853 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,0471347 0,06559057 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,0471347 0,06555266 ! vacuolar transport GO:0007034 36 22 0,000 0,0471347 0,06551479 ! central nervous system neuron development GO:0021954 46 22 0,000 0,0471347 0,06547696 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,0471347 0,06543918 ! fucose metabolic process GO:0006004 39 22 0,000 0,0471347 0,06540144 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,0471347 0,06536374 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,0471347 0,06532609 ! ureteric bud development GO:0001657 43 22 0,000 0,0471347 0,06528848 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,0471347 0,06525092 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,0471347 0,0652134 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,0471347 0,06517592 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,0471347 0,06513848 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,0471347 0,06510109 ! sarcomere organization GO:0045214 30 22 0,000 0,0471347 0,06506374 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,0471347 0,06502643 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,0471347 0,06498917 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,0471347 0,06495194 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,0471347 0,06491477 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,0471347 0,06487763 ! protein stabilization GO:0050821 39 22 0,000 0,0471347 0,06484053 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04922439 0,0676765 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04922439 0,06763785 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04922439 0,06759925 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04922439 0,06756068 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04922439 0,06752217 ! gluconeogenesis GO:0006094 33 23 0,000 0,04922439 0,06748369 ! viral genome replication GO:0019079 41 23 0,000 0,04922439 0,06744526 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04922439 0,06740688 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04922439 0,06736853 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04922439 0,06733023 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04922439 0,06729198 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04922439 0,06725376 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04922439 0,0672156 ! visual behavior GO:0007632 42 23 0,000 0,04922439 0,06717747 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04922439 0,06713939 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,04922439 0,06710135 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04922439 0,06706335 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04922439 0,0670254 ! peroxisome organization GO:0007031 37 23 0,000 0,04922439 0,06698749 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04922439 0,06694962 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04922439 0,0669118 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04922439 0,06687401 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04922439 0,06683628 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04922439 0,06679858 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04922439 0,06676092 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04922439 0,06672331 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04922439 0,06668574 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04922439 0,06664822 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04922439 0,06661073 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04922439 0,06657329 ! fatty acid transport GO:0015908 44 23 0,000 0,04922439 0,06653589 ! platelet activation GO:0030168 37 23 0,000 0,04922439 0,06649853 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04922439 0,06646121 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04922439 0,06642394 ! hormone transport GO:0009914 40 23 0,000 0,04922439 0,0663867 ! cell-cell recognition GO:0009988 25 23 0,000 0,04922439 0,06634951 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04922439 0,06631236 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04922439 0,06627525 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04922439 0,06623819 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04922439 0,06620116 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04922439 0,06616418 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05130956 0,06892842 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05130956 0,06888996 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05130956 0,06885154 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05130956 0,06881316 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05130956 0,06877482 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05130956 0,06873653 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05130956 0,06869828 ! spinal cord development GO:0021510 47 24 0,000 0,05130956 0,06866007 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05130956 0,0686219 ! digestive system process GO:0022600 39 24 0,000 0,05130956 0,06858378 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05130956 0,0685457 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05130956 0,06850766 ! regulation of behavior GO:0050795 43 24 0,000 0,05130956 0,06846966 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05130956 0,06843171 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05130956 0,0683938 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05130956 0,06835593 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05130956 0,0683181 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05130956 0,06828031 ! pallium development GO:0021543 49 24 0,000 0,05130956 0,06824257 ! pentose metabolic process GO:0019321 35 24 0,000 0,05130956 0,06820487 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05130956 0,0681672 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05130956 0,06812958 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05130956 0,06809201 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05130956 0,06805447 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05130956 0,06801697 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05130956 0,06797952 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05130956 0,06794211 ! regulation of amine transport GO:0051952 40 24 0,000 0,05130956 0,06790473 ! protein tetramerization GO:0051262 52 24 0,000 0,05130956 0,0678674 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,05339023 0,07058071 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,05339023 0,07054195 ! myelination GO:0042552 45 25 0,000 0,05339023 0,07050324 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,05339023 0,07046456 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,05339023 0,07042593 ! phototransduction GO:0007602 33 25 0,000 0,05339023 0,07038734 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,05339023 0,07034879 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,05339023 0,07031029 ! sperm motility GO:0030317 31 25 0,000 0,05339023 0,07027182 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,05339023 0,0702334 ! receptor metabolic process GO:0043112 46 25 0,000 0,05339023 0,07019502 ! chromosome condensation GO:0030261 45 25 0,000 0,05339023 0,07015669 ! response to starvation GO:0042594 42 25 0,000 0,05339023 0,07011839 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,05339023 0,07008014 ! neural crest cell development GO:0014032 54 25 0,000 0,05339023 0,07004193 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,05339023 0,07000376 ! negative regulation of cell development GO:0010721 73 25 0,000 0,05339023 0,06996563 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,05339023 0,06992754 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,05339023 0,0698895 ! interaction with host GO:0051701 62 25 0,000 0,05339023 0,06985149 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,05339023 0,06981353 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,05339023 0,06977561 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,05339023 0,06973773 ! immunoglobulin production GO:0002377 55 25 0,000 0,05339023 0,06969989 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,05339023 0,06966209 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,05339023 0,06962433 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,05339023 0,06958662 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,05339023 0,06954894 ! telomere organization GO:0032200 43 25 0,000 0,05339023 0,06951131 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,05339023 0,06947371 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,05339023 0,06943616 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05546641 0,07209734 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05546641 0,07205841 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05546641 0,07201952 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05546641 0,07198067 ! initiation of viral infection GO:0019059 57 26 0,000 0,05546641 0,07194187 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05546641 0,07190311 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05546641 0,07186439 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05546641 0,07182571 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05546641 0,07178707 ! molting cycle process GO:0022404 50 26 0,000 0,05546641 0,07174848 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05546641 0,07170993 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05546641 0,07167141 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05546641 0,07163294 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05546641 0,07159451 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,05546641 0,07155612 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05546641 0,07151778 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05546641 0,07147947 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05546641 0,07144121 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05546641 0,07140298 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05546641 0,0713648 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05546641 0,07132665 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05546641 0,07128855 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05546641 0,07125049 ! blastocyst development GO:0001824 49 26 0,000 0,05546641 0,07121247 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05546641 0,07117449 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05546641 0,07113655 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05546641 0,07109865 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,0575381 0,07371494 ! neuron fate commitment GO:0048663 48 27 0,000 0,0575381 0,07367571 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0575381 0,07363652 ! iron ion transport GO:0006826 59 27 0,000 0,0575381 0,07359737 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0575381 0,07355827 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0575381 0,0735192 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0575381 0,07348018 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0575381 0,0734412 ! fat cell differentiation GO:0045444 50 27 0,000 0,0575381 0,07340226 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0575381 0,07336336 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0575381 0,0733245 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0575381 0,07328568 ! autophagy GO:0006914 41 27 0,000 0,0575381 0,07324691 ! response to toxin GO:0009636 47 27 0,000 0,0575381 0,07320817 ! primary neural tube formation GO:0014020 51 27 0,000 0,0575381 0,07316948 ! base-excision repair GO:0006284 41 27 0,000 0,0575381 0,07313083 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0575381 0,07309222 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0575381 0,07305364 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0575381 0,07301511 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0575381 0,07297662 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0575381 0,07293818 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0575381 0,07289977 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0575381 0,0728614 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0575381 0,07282307 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05960531 0,07539978 ! circadian rhythm GO:0007623 50 28 0,000 0,05960531 0,07536016 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05960531 0,07532058 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05960531 0,07528104 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05960531 0,07524154 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05960531 0,07520208 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05960531 0,07516267 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05960531 0,0751233 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05960531 0,07508397 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05960531 0,07504468 ! synaptogenesis GO:0007416 42 28 0,000 0,05960531 0,07500543 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05960531 0,07496622 ! lipid oxidation GO:0034440 43 28 0,000 0,05960531 0,07492705 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05960531 0,07488792 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05960531 0,07484884 ! translational initiation GO:0006413 65 29 0,000 0,06166806 0,07739872 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06166806 0,07735837 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06166806 0,07731806 ! regulation of pH GO:0006885 43 29 0,000 0,06166806 0,07727779 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06166806 0,07723756 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06166806 0,07719737 ! catechol metabolic process GO:0009712 54 29 0,000 0,06166806 0,07715723 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06166806 0,07711713 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06166806 0,07707706 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06166806 0,07703705 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06166806 0,07699707 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06166806 0,07695713 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06166806 0,07691724 ! cell fate determination GO:0001709 60 29 0,000 0,06166806 0,07687738 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06166806 0,07683757 ! detection of light stimulus GO:0009583 38 29 0,000 0,06166806 0,0767978 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,06166806 0,07675807 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06166806 0,07671838 ! tissue homeostasis GO:0001894 48 29 0,000 0,06166806 0,07667873 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,06372635 0,07919711 ! zinc ion transport GO:0006829 45 30 0,000 0,06372635 0,07915622 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06372635 0,07911538 ! cell junction assembly GO:0034329 78 30 0,000 0,06372635 0,07907457 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06372635 0,07903381 ! acute-phase response GO:0006953 49 30 0,000 0,06372635 0,0789931 ! myofibril assembly GO:0030239 47 30 0,000 0,06372635 0,07895242 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06372635 0,07891179 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06372635 0,07887119 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06372635 0,07883064 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06372635 0,07879013 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06372635 0,07874967 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06372635 0,07870924 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06372635 0,07866886 ! eye morphogenesis GO:0048592 60 30 0,000 0,06372635 0,07862851 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06372635 0,07858821 ! response to heat GO:0009408 50 30 0,000 0,06372635 0,07854795 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,0657802 0,08103797 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,0657802 0,0809965 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,0657802 0,08095507 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,0657802 0,08091368 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,0657802 0,08087233 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,0657802 0,08083103 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,0657802 0,08078977 ! ovulation cycle process GO:0022602 49 31 0,000 0,0657802 0,08074855 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,0657802 0,08070737 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,0657802 0,08066624 ! iron ion homeostasis GO:0055072 54 31 0,000 0,0657802 0,08062514 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,0657802 0,08058409 ! mesoderm formation GO:0001707 69 31 0,000 0,0657802 0,08054308 ! natural killer cell activation GO:0030101 45 31 0,000 0,0657802 0,08050211 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,0657802 0,08046119 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,0657802 0,0804203 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,0657802 0,08037946 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,0657802 0,08033866 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,0657802 0,0802979 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06782961 0,08275762 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06782961 0,08271568 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06782961 0,08267377 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06782961 0,08263191 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06782961 0,0825901 ! spliceosome assembly GO:0000245 67 32 0,000 0,06782961 0,08254832 ! spindle organization GO:0007051 46 32 0,000 0,06782961 0,08250659 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06782961 0,0824649 ! metanephros development GO:0001656 74 32 0,000 0,06782961 0,08242325 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06782961 0,08238164 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06782961 0,08234008 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06782961 0,08229855 ! muscle cell development GO:0055001 49 32 0,000 0,06782961 0,08225707 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06782961 0,08221563 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06782961 0,08217424 ! ovulation cycle GO:0042698 51 32 0,000 0,06782961 0,08213288 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06782961 0,08209156 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06782961 0,08205029 ! hindbrain development GO:0030902 61 32 0,000 0,06782961 0,08200906 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06782961 0,08196787 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06782961 0,08192672 ! gene silencing GO:0016458 65 32 0,000 0,06782961 0,08188562 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06987459 0,08431206 ! post-embryonic development GO:0009791 69 33 0,000 0,06987459 0,0842698 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06987459 0,08422758 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06987459 0,08418541 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06987459 0,08414327 ! formation of primary germ layer GO:0001704 72 33 0,000 0,06987459 0,08410118 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06987459 0,08405913 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06987459 0,08401712 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06987459 0,08397515 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06987459 0,08393323 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06987459 0,08389134 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07191515 0,08629818 ! glial cell differentiation GO:0010001 63 34 0,000 0,07191515 0,08625516 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07191515 0,08621218 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07191515 0,08616925 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07191515 0,08612636 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07191515 0,08608351 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07191515 0,0860407 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07191515 0,08599794 ! mismatch repair GO:0006298 46 34 0,000 0,07191515 0,08595521 ! spermatid development GO:0007286 63 34 0,000 0,07191515 0,08591254 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07191515 0,0858699 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07191515 0,08582731 ! placenta development GO:0001890 53 34 0,000 0,07191515 0,08578475 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,07191515 0,08574224 ! regulation of muscle development GO:0048634 70 35 0,000 0,0739513 0,08812622 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0739513 0,08808259 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0739513 0,08803901 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0739513 0,08799547 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0739513 0,08795197 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0739513 0,08790851 ! odontogenesis GO:0042476 66 35 0,000 0,0739513 0,0878651 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0739513 0,08782173 ! female gonad development GO:0008585 58 35 0,000 0,0739513 0,08777841 ! telencephalon development GO:0021537 68 35 0,000 0,0739513 0,08773512 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,0739513 0,08769188 ! neural tube formation GO:0001841 67 35 0,000 0,0739513 0,08764869 ! vesicle localization GO:0051648 64 35 0,000 0,0739513 0,08760553 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07598306 0,08996813 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07598306 0,08992387 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07598306 0,08987966 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07598306 0,08983549 ! cell junction organization GO:0034330 86 36 0,000 0,07598306 0,08979137 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07598306 0,08974729 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07598306 0,08970325 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07598306 0,08965926 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07598306 0,08961531 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07598306 0,0895714 ! aerobic respiration GO:0009060 55 36 0,000 0,07598306 0,08952754 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,07598306 0,08948372 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07598306 0,08943994 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07598306 0,0893962 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07801042 0,09173659 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07801042 0,09169178 ! meiosis I GO:0007127 65 37 0,000 0,07801042 0,09164701 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07801042 0,09160228 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07801042 0,09155759 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07801042 0,09151295 ! organic anion transport GO:0015711 68 37 0,000 0,07801042 0,09146836 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07801042 0,0914238 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07801042 0,09137929 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07801042 0,09133483 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07801042 0,0912904 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07801042 0,09124602 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07801042 0,09120169 ! pigment metabolic process GO:0042440 80 37 0,000 0,07801042 0,09115739 ! spermatid differentiation GO:0048515 66 37 0,000 0,07801042 0,09111314 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,0800334 0,09343055 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,0800334 0,09338524 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,0800334 0,09333997 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,0800334 0,09329475 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,0800334 0,09324957 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,0800334 0,09320444 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,0800334 0,09315934 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,0800334 0,0931143 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,0800334 0,09306929 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,0800334 0,09302433 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,0800334 0,09297941 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,0800334 0,09293454 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,0800334 0,09288971 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 0,000 0,0800334 0,09284492 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,08205201 0,09514079 ! learning GO:0007612 77 39 0,000 0,08205201 0,09509496 ! segmentation GO:0035282 67 39 0,000 0,08205201 0,09504918 ! ion transmembrane transport GO:0034220 66 39 0,000 0,08205201 0,09500344 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,08205201 0,09495774 ! RNA modification GO:0009451 57 39 0,000 0,08205201 0,09491209 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,08205201 0,09486648 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,08406626 0,09714862 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,08406626 0,09710198 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,08406626 0,09705539 ! feeding behavior GO:0007631 59 40 0,000 0,08406626 0,09700884 ! negative regulation of binding GO:0051100 72 40 0,000 0,08406626 0,09696233 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,08406626 0,09691587 ! mesenchymal cell development GO:0014031 87 40 0,000 0,08406626 0,09686946 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,08406626 0,09682308 ! maintenance of protein location GO:0045185 91 40 0,000 0,08406626 0,09677676 ! cytokinesis GO:0000910 72 40 0,000 0,08406626 0,09673048 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08607616 0,09899581 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08607616 0,09894851 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08607616 0,09890126 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08607616 0,09885405 ! gliogenesis GO:0042063 88 41 0,000 0,08607616 0,09880689 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08607616 0,09875977 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08607616 0,09871269 ! female gamete generation GO:0007292 61 41 0,000 0,08607616 0,09866567 ! polyol metabolic process GO:0019751 66 41 0,000 0,08607616 0,09861868 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08607616 0,09857174 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08808171 0,10082045 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08808171 0,10077251 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08808171 0,10072461 ! regulation of tube size GO:0035150 71 42 0,000 0,08808171 0,10067676 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08808171 0,10062896 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08808171 0,1005812 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08808171 0,10053349 ! neuron migration GO:0001764 79 42 0,000 0,08808171 0,10048582 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08808171 0,10043819 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08808171 0,10039062 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,09008293 0,10262288 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,09008293 0,10257431 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,09008293 0,10252579 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,09008293 0,10247731 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,09008293 0,10242888 ! glucose transport GO:0015758 65 43 0,000 0,09008293 0,1023805 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,09008293 0,10233216 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,09008293 0,10228387 ! neural tube development GO:0021915 77 43 0,000 0,09008293 0,10223562 ! striated muscle contraction GO:0006941 77 43 0,000 0,09008293 0,10218742 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,09008293 0,10213926 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09207982 0,10435423 ! hexose transport GO:0008645 67 44 0,000 0,09207982 0,1043051 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09207982 0,10425602 ! double-strand break repair GO:0006302 81 44 0,000 0,09207982 0,10420698 ! biopolymer methylation GO:0043414 84 44 0,000 0,09207982 0,10415799 ! B cell differentiation GO:0030183 107 44 0,000 0,09207982 0,10410904 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09207982 0,10406014 ! developmental growth GO:0048589 82 44 0,000 0,09207982 0,10401129 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09207982 0,10396248 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09407239 0,10616237 ! glycolysis GO:0006096 65 45 0,000 0,09407239 0,1061126 ! leukocyte migration GO:0050900 68 45 0,000 0,09407239 0,10606288 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09407239 0,1060132 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,09407239 0,10596357 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,09407239 0,10591398 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09407239 0,10586444 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09407239 0,10581495 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09407239 0,1057655 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09407239 0,1057161 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09407239 0,10566675 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,09606066 0,10784972 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,09606066 0,10779942 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,09606066 0,10774916 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,09606066 0,10769895 ! pigmentation GO:0043473 100 46 0,000 0,09606066 0,10764879 ! positive regulation of defense response GO:0031349 76 47 0,000 0,09804463 0,10982094 ! response to calcium ion GO:0051592 81 47 0,000 0,09804463 0,10976984 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,09804463 0,10971878 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,09804463 0,10966778 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,09804463 0,10961682 ! JNK cascade GO:0007254 91 47 0,000 0,09804463 0,1095659 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,09804463 0,10951504 ! methylation GO:0032259 90 47 0,000 0,09804463 0,10946422 ! mitochondrial transport GO:0006839 82 48 0,000 0,10002432 0,11162268 ! Notch signaling pathway GO:0007219 96 48 0,000 0,10002432 0,11157093 ! cellular component disassembly GO:0022411 86 48 0,000 0,10002432 0,11151923 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,10002432 0,11146758 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,10002432 0,11141597 ! activation of caspase activity GO:0006919 84 48 0,000 0,10002432 0,11136442 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,10002432 0,11131291 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,10002432 0,11126144 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,10002432 0,11121003 ! regulation of action potential GO:0001508 95 49 0,000 0,10199972 0,11335396 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10199972 0,11330163 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10199972 0,11324934 ! regulation of ion transport GO:0043269 77 49 0,000 0,10199972 0,1131971 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10199972 0,11314492 ! peptide metabolic process GO:0006518 76 49 0,000 0,10199972 0,11309278 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10199972 0,11304068 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10199972 0,11298864 ! endocrine system development GO:0035270 104 49 0,000 0,10199972 0,11293664 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10199972 0,11288469 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10199972 0,11283279 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10199972 0,11278094 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10199972 0,11272913 ! neuromuscular process GO:0050905 99 50 0,000 0,10397085 0,11485485 ! regulation of ossification GO:0030278 117 50 0,000 0,10397085 0,11480214 ! histone modification GO:0016570 91 50 0,000 0,10397085 0,11474948 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10397085 0,11469687 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10397085 0,1146443 ! positive regulation of binding GO:0051099 78 51 0,000 0,10593772 0,11675958 ! viral infectious cycle GO:0019058 99 51 0,000 0,10593772 0,11670612 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10593772 0,11665271 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10593772 0,11659934 ! excretion GO:0007588 83 51 0,000 0,10593772 0,11654603 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10593772 0,11649276 ! chromatin remodeling GO:0006338 109 51 0,000 0,10593772 0,11643954 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10593772 0,11638637 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10593772 0,11633325 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,10593772 0,11628018 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10593772 0,11622716 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,10790034 0,11832645 ! positive regulation of growth GO:0045927 90 52 0,000 0,10790034 0,11827254 ! covalent chromatin modification GO:0016569 101 52 0,000 0,10790034 0,11821868 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,10790034 0,11816487 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10985872 0,12025481 ! RNA catabolic process GO:0006401 93 53 0,000 0,10985872 0,12020013 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10985872 0,12014549 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10985872 0,1200909 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10985872 0,12003637 ! cell maturation GO:0048469 100 53 0,000 0,10985872 0,11998188 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,10985872 0,11992744 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11181286 0,12200532 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11181286 0,12195002 ! cell recognition GO:0008037 85 54 0,000 0,11181286 0,12189476 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11181286 0,12183956 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11181286 0,1217844 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11181286 0,12172929 ! chloride transport GO:0006821 90 55 0,000 0,11376278 0,12379613 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11376278 0,12374016 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,11376278 0,12368425 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,11376278 0,12362838 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11376278 0,12357257 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11376278 0,12351681 ! aging GO:0007568 103 55 0,000 0,11376278 0,12346109 ! gastrulation GO:0007369 112 55 0,000 0,11376278 0,12340543 ! heart morphogenesis GO:0003007 97 55 0,000 0,11376278 0,12334982 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11376278 0,12329425 ! RNA elongation GO:0006354 79 55 0,000 0,11376278 0,12323874 ! nuclear export GO:0051168 97 55 0,000 0,11376278 0,12318328 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11376278 0,12312786 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11570848 0,12517743 ! sensory perception of smell GO:0007608 80 56 0,000 0,11570848 0,12512117 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11570848 0,12506496 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,11570848 0,1250088 ! regulation of DNA replication GO:0006275 101 56 0,000 0,11570848 0,12495269 ! proton transport GO:0015992 94 56 0,000 0,11570848 0,12489663 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,11764997 0,12693535 ! maintenance of location GO:0051235 118 57 0,000 0,11764997 0,12687845 ! hydrogen transport GO:0006818 97 58 0,000 0,11958727 0,12890993 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,11958727 0,1288522 ! regulation of endocytosis GO:0030100 91 58 0,000 0,11958727 0,12879452 ! adult behavior GO:0030534 99 58 0,000 0,11958727 0,1287369 ! positive regulation of secretion GO:0051047 95 59 0,000 0,12152037 0,1307594 ! regulation of cellular component size GO:0032535 109 59 0,000 0,12152037 0,13070095 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,12152037 0,13064255 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,12152037 0,1305842 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,12152037 0,1305259 ! DNA catabolic process GO:0006308 86 59 0,000 0,12152037 0,13046766 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,12152037 0,13040946 ! establishment of organelle localization GO:0051656 109 59 0,000 0,12152037 0,13035132 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,1234493 0,13236141 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,1234493 0,13230246 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,1234493 0,13224355 ! regulation of heart contraction GO:0008016 110 60 0,000 0,1234493 0,1321847 ! camera-type eye development GO:0043010 116 60 0,000 0,1234493 0,1321259 ! kidney development GO:0001822 122 60 0,000 0,1234493 0,13206715 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12537405 0,13406665 ! mesoderm development GO:0007498 119 61 0,000 0,12537405 0,1340071 ! tRNA processing GO:0008033 89 61 0,000 0,12537405 0,13394759 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12537405 0,13388814 ! viral reproductive process GO:0022415 126 62 0,000 0,12729465 0,13587885 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12729465 0,13581859 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,12729465 0,13575839 ! regulation of mitosis GO:0007088 105 63 0,000 0,12921108 0,13774119 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,12921108 0,13768019 ! detection of external stimulus GO:0009581 91 63 0,000 0,12921108 0,13761924 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12921108 0,13755835 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,12921108 0,13749751 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,13112338 0,13947075 ! cell redox homeostasis GO:0045454 102 64 0,000 0,13112338 0,13940912 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,13112338 0,13934755 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,13112338 0,13928602 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,13112338 0,13922456 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13303153 0,1411883 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13303153 0,14112605 ! germ cell development GO:0007281 118 65 0,000 0,13303153 0,14106385 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,13303153 0,14100171 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13493557 0,14295683 ! actin filament organization GO:0007015 148 66 0,000 0,13493557 0,14289391 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13493557 0,14283105 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13493557 0,14276824 ! secondary metabolic process GO:0019748 116 66 0,000 0,13493557 0,14270548 ! developmental maturation GO:0021700 116 66 0,000 0,13493557 0,14264278 ! cell projection assembly GO:0030031 120 66 0,000 0,13493557 0,14258014 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13683548 0,14452421 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13683548 0,1444608 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,13683548 0,14439744 ! activation of MAPK activity GO:0000187 115 67 0,000 0,13683548 0,14433413 ! chromosome segregation GO:0007059 113 67 0,000 0,13683548 0,14427088 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13683548 0,14420769 ! hexose catabolic process GO:0019320 104 67 0,000 0,13683548 0,14414455 ! adaptive immune response GO:0002250 119 67 0,000 0,13683548 0,14408147 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,13683548 0,14401844 ! amino acid transport GO:0006865 125 68 0,000 0,13873128 0,14594992 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,13873128 0,14588613 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,13873128 0,14582239 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,13873128 0,14575872 ! viral reproduction GO:0016032 134 68 0,000 0,13873128 0,14569509 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,13873128 0,14563153 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,13873128 0,14556801 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,14062298 0,14748862 ! negative regulation of cell size GO:0045792 134 69 0,000 0,14062298 0,14742435 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,14062298 0,14736014 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,14062298 0,14729599 ! urogenital system development GO:0001655 137 69 0,000 0,14062298 0,14723189 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,14062298 0,14716785 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,14062298 0,14710387 ! antigen processing and presentation GO:0019882 104 69 0,000 0,14062298 0,14703994 ! amine catabolic process GO:0009310 117 71 0,000 0,14439412 0,15091757 ! humoral immune response GO:0006959 109 71 0,000 0,14439412 0,15085204 ! B cell activation GO:0042113 160 71 0,000 0,14439412 0,15078656 ! acute inflammatory response GO:0002526 113 72 0,000 0,14627357 0,15268295 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14627357 0,15261674 ! carbohydrate transport GO:0008643 110 72 0,000 0,14627357 0,15255059 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14627357 0,15248449 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14627357 0,15241845 ! learning or memory GO:0007611 147 73 0,000 0,14814895 0,15430579 ! regulation of blood pressure GO:0008217 125 73 0,000 0,14814895 0,15423902 ! axon guidance GO:0007411 139 73 0,000 0,14814895 0,15417231 ! fertilization GO:0009566 90 73 0,000 0,14814895 0,15410565 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,15002028 0,15598479 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,15002028 0,15591741 ! neurotransmitter transport GO:0006836 123 74 0,000 0,15002028 0,15585008 ! meiosis GO:0007126 121 74 0,000 0,15002028 0,15578282 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,15002028 0,15571561 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,15002028 0,15564847 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,15002028 0,15558138 ! eye development GO:0001654 143 74 0,000 0,15002028 0,15551434 ! organelle localization GO:0051640 136 74 0,000 0,15002028 0,15544737 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,15188756 0,15731445 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,15188756 0,15724676 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,15188756 0,15717913 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,15188756 0,15711155 ! meiotic cell cycle GO:0051321 122 75 0,000 0,15188756 0,15704403 ! rhythmic process GO:0048511 128 75 0,000 0,15188756 0,15697657 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1537508 0,15883401 ! defense response to bacterium GO:0042742 89 76 0,000 0,1537508 0,15876585 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,1537508 0,15869773 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1537508 0,15862968 ! regulation of catabolic process GO:0009894 161 76 0,000 0,1537508 0,15856169 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15561 0,16041031 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15561 0,16034162 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15561 0,16027298 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,15746519 0,16211435 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,15746519 0,16204502 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,15746519 0,16197574 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,15931636 0,1638099 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,15931636 0,16373992 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,15931636 0,16367001 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,15931636 0,16360015 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,15931636 0,16353036 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,16116352 0,16535584 ! response to metal ion GO:0010038 140 80 0,000 0,16116352 0,16528535 ! muscle cell differentiation GO:0042692 159 80 0,000 0,16116352 0,16521493 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,16116352 0,16514456 ! inorganic anion transport GO:0015698 138 80 0,000 0,16116352 0,16507426 ! digestion GO:0007586 112 81 0,000 0,16300669 0,16689111 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,16300669 0,16682012 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16300669 0,16674919 ! response to drug GO:0042493 143 82 0,000 0,16484587 0,16855893 ! response to nutrient GO:0007584 125 82 0,000 0,16484587 0,16848732 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16484587 0,16841578 ! regulation of lyase activity GO:0051339 160 83 0,000 0,16668107 0,17021844 ! negative regulation of transport GO:0051051 153 84 0,000 0,16851229 0,17201552 ! negative regulation of growth GO:0045926 155 84 0,000 0,16851229 0,17194257 ! regulation of ligase activity GO:0051340 142 84 0,000 0,16851229 0,17186968 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,16851229 0,17179685 ! response to unfolded protein GO:0006986 131 85 0,000 0,17033956 0,17358618 ! nucleosome assembly GO:0006334 122 85 0,000 0,17033956 0,17351269 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,17033956 0,17343926 ! amine biosynthetic process GO:0009309 138 86 0,000 0,17216286 0,1752216 ! response to inorganic substance GO:0010035 153 86 0,000 0,17216286 0,17514751 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,17216286 0,17507348 ! chromatin assembly GO:0031497 124 86 0,000 0,17216286 0,17499951 ! tube morphogenesis GO:0035239 176 86 0,000 0,17216286 0,17492561 ! mitochondrion organization GO:0007005 148 86 0,000 0,17216286 0,17485177 ! alcohol catabolic process GO:0046164 130 86 0,000 0,17216286 0,174778 ! amine transport GO:0015837 155 86 0,000 0,17216286 0,17470428 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17398223 0,17647607 ! cellular respiration GO:0045333 135 88 0,000 0,17579765 0,17824237 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,17579765 0,17816729 ! regulation of DNA binding GO:0051101 155 88 0,000 0,17579765 0,17809227 ! regulation of neurological system process GO:0031644 148 88 0,000 0,17579765 0,17801732 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,17579765 0,17794243 ! cellular defense response GO:0006968 114 89 0,000 0,17760914 0,17970042 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,17760914 0,17962488 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,17941672 0,18137673 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,17941672 0,18130055 ! response to protein stimulus GO:0051789 149 91 0,000 0,18122038 0,18304627 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,18122038 0,18296946 ! regulation of defense response GO:0031347 149 92 0,000 0,18302013 0,18470908 ! nucleosome organization GO:0034728 138 92 0,000 0,18302013 0,18463163 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18302013 0,18455425 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18302013 0,18447693 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,18481599 0,18620908 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,18481599 0,18613113 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,18660796 0,18785722 ! female pregnancy GO:0007565 164 94 0,000 0,18660796 0,18777865 ! transcription initiation GO:0006352 153 94 0,000 0,18660796 0,18770015 ! forebrain development GO:0030900 188 95 0,000 0,18839605 0,18941952 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,19018027 0,19113356 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,19018027 0,19105375 ! positive regulation of immune response GO:0050778 156 96 0,000 0,19018027 0,19097401 ! detection of stimulus GO:0051606 151 96 0,000 0,19018027 0,19089434 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,19196063 0,19260103 ! protein ubiquitination GO:0016567 217 97 0,000 0,19196063 0,19252075 ! hormone metabolic process GO:0042445 157 97 0,000 0,19196063 0,19244053 ! response to virus GO:0009615 160 98 0,000 0,19373713 0,19414058 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,19373713 0,19405976 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,19373713 0,193979 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,19550979 0,19567244 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,19550979 0,19559108 ! cell cycle arrest GO:0007050 213 100 0,000 0,19727861 0,19727861