pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/799-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein complex assembly GO:0043254 117 61 4,000 1,796E-08 4,322E-05 ! nuclear migration GO:0007097 12 6 2,000 4,329E-08 5,207E-05 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 4,329E-08 3,472E-05 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 7,568E-08 4,552E-05 ! macrophage differentiation GO:0030225 11 7 2,000 7,568E-08 3,642E-05 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,21E-07 4,851E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,813E-07 6,231E-05 ! nucleus localization GO:0051647 19 11 2,000 3,555E-07 1,069E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 4,735E-07 1,266E-04 ! filopodium assembly GO:0046847 32 16 2,000 1,201E-06 2,889E-04 ! microspike assembly GO:0030035 36 17 2,000 1,457E-06 3,187E-04 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 1,501E-06 3,01E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,436E-06 4,508E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 3,773E-06 6,485E-04 ! vasculogenesis GO:0001570 46 25 2,000 4,891E-06 7,846E-04 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,524E-06 8,307E-04 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 6,209E-06 8,788E-04 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 7,742E-06 1,035E-03 ! negative regulation of neuron apoptosis GO:0043524 56 29 2,000 7,742E-06 9,804E-04 ! negative regulation of secretion GO:0051048 63 35 2,000 1,379E-05 1,659E-03 ! negative regulation of cell adhesion GO:0007162 81 35 2,000 1,379E-05 1,58E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,634E-05 1,787E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,634E-05 1,71E-03 ! anagen GO:0042640 6 5 1,000 1,716E-05 1,72E-03 ! response to food GO:0032094 6 5 1,000 1,716E-05 1,651E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 1,716E-05 1,588E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 1,716E-05 1,529E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 1,716E-05 1,474E-03 ! cytokinesis GO:0000910 72 40 2,000 2,072E-05 1,719E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,571E-05 2,062E-03 ! hair follicle maturation GO:0048820 7 6 1,000 2,571E-05 1,996E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 2,571E-05 1,933E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,167E-05 2,309E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 3,167E-05 2,241E-03 ! protein homooligomerization GO:0051260 76 47 2,000 3,379E-05 2,323E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 3,597E-05 2,404E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 3,597E-05 2,339E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! vesicle fusion GO:0006906 17 7 1,000 3,597E-05 2,277E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 3,597E-05 2,219E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 3,597E-05 2,163E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 3,597E-05 2,111E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,601E-05 2,063E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 4,074E-05 2,279E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,792E-05 2,62E-03 ! Schwann cell differentiation GO:0014037 19 8 1,000 4,792E-05 2,562E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 4,792E-05 2,506E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 4,792E-05 2,453E-03 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 4,855E-05 2,434E-03 ! regulation of protein polymerization GO:0032271 103 53 2,000 4,855E-05 2,384E-03 ! response to UV GO:0009411 104 53 2,000 4,855E-05 2,336E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 5,729E-05 2,703E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 6,042E-05 2,796E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 6,155E-05 2,794E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 6,155E-05 2,743E-03 GO:0010469|regulation of receptor activity, ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 6,155E-05 2,693E-03 ! gas homeostasis GO:0033483 16 9 1,000 6,155E-05 2,645E-03 ! establishment of organelle localization GO:0051656 109 59 2,000 6,701E-05 2,828E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 7,405E-05 3,072E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 7,688E-05 3,135E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,688E-05 3,083E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 7,688E-05 3,032E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 7,688E-05 2,983E-03 GO:0005978|glycogen biosynthetic process, ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 7,688E-05 2,936E-03 ! blastocyst formation GO:0001825 17 10 1,000 7,688E-05 2,89E-03 ! myeloid cell differentiation GO:0030099 111 65 2,000 8,954E-05 3,314E-03 ! cell projection assembly GO:0030031 120 66 2,000 9,371E-05 3,416E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 9,388E-05 3,371E-03 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 9,388E-05 3,322E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! cardiac cell differentiation GO:0035051 31 11 1,000 9,388E-05 3,274E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 9,802E-05 3,369E-03 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,024E-04 3,472E-03 ! negative regulation of cell size GO:0045792 134 69 2,000 1,07E-04 3,576E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,126E-04 3,71E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,126E-04 3,66E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,126E-04 3,611E-03 ! entry into host cell GO:0030260 32 12 1,000 1,126E-04 3,564E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! cranial nerve development GO:0021545 20 12 1,000 1,126E-04 3,517E-03 ! gland morphogenesis GO:0022612 29 12 1,000 1,126E-04 3,472E-03 ! T cell homeostasis GO:0043029 25 12 1,000 1,126E-04 3,428E-03 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 1,165E-04 3,504E-03 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,215E-04 3,608E-03 ! organelle localization GO:0051640 136 74 2,000 1,318E-04 3,867E-03 ! lipid localization GO:0010876 28 13 1,000 1,329E-04 3,853E-03 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 1,329E-04 3,807E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,329E-04 3,762E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,329E-04 3,719E-03 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,329E-04 3,676E-03 ! protein oligomerization GO:0051259 139 78 2,000 1,541E-04 4,213E-03 ! regulation of peptidase activity GO:0052547 134 79 2,000 1,6E-04 4,326E-03 ! regulation of vasodilation GO:0042312 26 15 1,000 1,786E-04 4,775E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,786E-04 4,723E-03 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,786E-04 4,672E-03 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 1,787E-04 4,624E-03 ! negative regulation of transport GO:0051051 153 84 2,000 1,919E-04 4,913E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 2,04E-04 5,166E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,04E-04 5,112E-03 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,04E-04 5,059E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,04E-04 5,008E-03 ! regulation of protein transport GO:0051223 154 87 2,000 2,129E-04 5,175E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of cell adhesion GO:0030155 212 89 2,000 2,277E-04 5,479E-03 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 2,31E-04 5,502E-03 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,31E-04 5,448E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,31E-04 5,396E-03 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 1,000 2,31E-04 5,344E-03 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 2,596E-04 5,949E-03 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,596E-04 5,893E-03 ! positive regulation of proteolysis GO:0045862 31 18 1,000 2,596E-04 5,838E-03 ! response to retinoic acid GO:0032526 26 18 1,000 2,596E-04 5,784E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,596E-04 5,731E-03 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 2,596E-04 5,679E-03 ! nerve development GO:0021675 28 18 1,000 2,596E-04 5,628E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 2,76E-04 5,929E-03 ! leukocyte differentiation GO:0002521 202 96 2,000 2,847E-04 6,061E-03 ! lipid phosphorylation GO:0046834 35 19 1,000 2,899E-04 6,119E-03 ! response to vitamin A GO:0033189 27 19 1,000 2,899E-04 6,066E-03 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 2,899E-04 6,014E-03 ! regulation of protein localization GO:0032880 176 97 2,000 2,935E-04 6,035E-03 ! interphase GO:0051325 213 98 2,000 3,025E-04 6,167E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,219E-04 6,508E-03 ! response to vitamin GO:0033273 31 20 1,000 3,219E-04 6,454E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,219E-04 6,4E-03 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,219E-04 6,348E-03 ! peptidyl-serine modification GO:0018209 43 20 1,000 3,219E-04 6,296E-03 ! inactivation of MAPK activity GO:0000188 39 21 1,000 3,555E-04 6,897E-03 ! regulation of vasoconstriction GO:0019229 39 21 1,000 3,555E-04 6,842E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 3,907E-04 7,46E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,907E-04 7,401E-03 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 3,907E-04 7,344E-03 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 3,907E-04 7,287E-03 GO:0060415|muscle tissue morphogenesis, ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,907E-04 7,231E-03 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,907E-04 7,175E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 3,907E-04 7,121E-03 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 4,275E-04 7,734E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 4,275E-04 7,676E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 4,275E-04 7,62E-03 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 4,66E-04 8,244E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,66E-04 8,184E-03 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 4,66E-04 8,125E-03 ! vesicle docking GO:0048278 47 24 1,000 4,66E-04 8,066E-03 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,66E-04 8,009E-03 ! membrane depolarization GO:0051899 39 24 1,000 4,66E-04 7,952E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,66E-04 7,896E-03 ! leukocyte homeostasis GO:0001776 44 24 1,000 4,66E-04 7,841E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,061E-04 8,456E-03 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 5,061E-04 8,398E-03 ! interaction with host GO:0051701 62 25 1,000 5,061E-04 8,34E-03 ! regulation of blood coagulation GO:0030193 40 25 1,000 5,061E-04 8,284E-03 ! initiation of viral infection GO:0019059 57 26 1,000 5,478E-04 8,906E-03 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 5,478E-04 8,846E-03 ! molting cycle process GO:0022404 50 26 1,000 5,478E-04 8,787E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 5,478E-04 8,729E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 5,478E-04 8,671E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,478E-04 8,615E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 5,478E-04 8,559E-03 ! positive regulation of nuclear division GO:0051785 40 26 1,000 5,478E-04 8,504E-03 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 5,478E-04 8,449E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,911E-04 9,059E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,911E-04 9,002E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 6,826E-04 0,01032957 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 6,826E-04 0,01026501 ! regulation of coagulation GO:0050818 46 29 1,000 6,826E-04 0,01020125 ! membrane docking GO:0022406 61 30 1,000 7,308E-04 0,01085333 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 7,308E-04 0,01078674 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 7,308E-04 0,01072097 ! regulation of B cell activation GO:0050864 50 30 1,000 7,308E-04 0,01065599 ! response to heat GO:0009408 50 30 1,000 7,308E-04 0,0105918 ! cholesterol homeostasis GO:0042632 53 31 1,000 7,805E-04 0,01124503 GO:0055092|sterol homeostasis, ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 7,805E-04 0,01117809 ! triglyceride metabolic process GO:0006641 43 31 1,000 7,805E-04 0,01111195 ! cholesterol transport GO:0030301 56 32 1,000 8,319E-04 0,01177313 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 8,319E-04 0,01170428 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 8,319E-04 0,01163624 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 8,319E-04 0,01156898 ! peripheral nervous system development GO:0007422 64 32 1,000 8,319E-04 0,01150249 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,319E-04 0,01143676 ! sterol transport GO:0015918 57 33 1,000 8,848E-04 0,01209528 ! glial cell differentiation GO:0010001 63 34 1,000 9,393E-04 0,01276791 ! placenta development GO:0001890 53 34 1,000 9,393E-04 0,01269618 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 9,393E-04 0,01262525 ! neutral lipid metabolic process GO:0006638 50 35 1,000 9,954E-04 0,01330485 GO:0006639|acylglycerol metabolic process, ! regulation of microtubule-based process GO:0032886 78 35 1,000 9,954E-04 0,01323134 ! regulation of proteolysis GO:0030162 72 36 1,000 1,053E-03 0,01392099 ! glycerol ether metabolic process GO:0006662 53 37 1,000 1,112E-03 0,01462378 ! tissue remodeling GO:0048771 76 37 1,000 1,112E-03 0,01454431 ! glycogen metabolic process GO:0005977 61 37 1,000 1,112E-03 0,01446569 ! lipid homeostasis GO:0055088 67 38 1,000 1,173E-03 0,0151745 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,173E-03 0,01509336 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 1,173E-03 0,01501307 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 1,235E-03 0,01572766 ! organic ether metabolic process GO:0018904 55 39 1,000 1,235E-03 0,01564488 ! gliogenesis GO:0042063 88 41 1,000 1,365E-03 0,01719331 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 1,432E-03 0,01794389 ! regulation of protein secretion GO:0050708 71 42 1,000 1,432E-03 0,01785091 ! energy reserve metabolic process GO:0006112 74 43 1,000 1,501E-03 0,01860957 ! glucose transport GO:0015758 65 43 1,000 1,501E-03 0,01851414 ! striated muscle cell differentiation GO:0051146 82 43 1,000 1,501E-03 0,01841968 ! hexose transport GO:0008645 67 44 1,000 1,571E-03 0,01918275 GO:0015749|monosaccharide transport, ! developmental growth GO:0048589 82 44 1,000 1,571E-03 0,01908587 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 1,642E-03 0,01985655 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 1,642E-03 0,01975727 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 1,642E-03 0,01965898 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 1,642E-03 0,01956166 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 1,642E-03 0,01946529 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 1,716E-03 0,02023335 ! positive regulation of protein transport GO:0051222 72 46 1,000 1,716E-03 0,02013465 ! regulation of JNK cascade GO:0046328 94 47 1,000 1,79E-03 0,02090989 ! Notch signaling pathway GO:0007219 96 48 1,000 1,867E-03 0,02169542 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 1,867E-03 0,02159111 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 1,867E-03 0,0214878 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 1,867E-03 0,02138548 ! response to temperature stimulus GO:0009266 76 49 1,000 1,944E-03 0,02217124 ! viral infectious cycle GO:0019058 99 51 1,000 2,105E-03 0,02388423 ! vesicle organization GO:0016050 107 51 1,000 2,105E-03 0,0237721 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 2,105E-03 0,02366101 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 2,105E-03 0,02355096 ! regulation of muscle contraction GO:0006937 81 52 1,000 2,187E-03 0,02435918 ! membrane fusion GO:0006944 110 52 1,000 2,187E-03 0,02424692 ! positive regulation of growth GO:0045927 90 52 1,000 2,187E-03 0,0241357 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 2,187E-03 0,02402549 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 2,271E-03 0,02483336 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 2,443E-03 0,02659593 ! regulation of protein catabolic process GO:0042176 116 55 1,000 2,443E-03 0,02647612 ! heart morphogenesis GO:0003007 97 55 1,000 2,443E-03 0,0263574 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 2,443E-03 0,02623973 ! regulation of actin filament length GO:0030832 105 56 1,000 2,531E-03 0,02706794 ! lipid modification GO:0030258 97 57 1,000 2,621E-03 0,02790471 ! regulation of intracellular transport GO:0032386 101 57 1,000 2,621E-03 0,02778179 ! regulation of cellular component size GO:0032535 109 59 1,000 2,805E-03 0,02960333 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 2,9E-03 0,03046488 ! viral reproductive process GO:0022415 126 62 1,000 3,093E-03 0,03235175 ! regulation of mitosis GO:0007088 105 63 1,000 3,191E-03 0,03323997 GO:0051783|regulation of nuclear division, ! germ cell development GO:0007281 118 65 1,000 3,393E-03 0,03518993 ! developmental maturation GO:0021700 116 66 1,000 3,496E-03 0,03610363 ! regulation of cellular response to stress GO:0080135 128 67 1,000 3,601E-03 0,03702446 ! negative regulation of cell growth GO:0030308 132 67 1,000 3,601E-03 0,03686691 ! activation of MAPK activity GO:0000187 115 67 1,000 3,601E-03 0,0367107 ! homeostasis of number of cells GO:0048872 114 67 1,000 3,601E-03 0,0365558 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 3,601E-03 0,0364022 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 3,707E-03 0,03731712 ! viral reproduction GO:0016032 134 68 1,000 3,707E-03 0,03716163 ! regulation of caspase activity GO:0043281 122 72 1,000 4,145E-03 0,04138493 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 4,145E-03 0,04121392 ! carbohydrate transport GO:0008643 110 72 1,000 4,145E-03 0,04104431 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 4,373E-03 0,04312274 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 4,373E-03 0,04294673 ! regulation of catabolic process GO:0009894 161 76 1,000 4,607E-03 0,04505621 ! regulation of actin filament-based process GO:0032970 152 77 1,000 4,726E-03 0,04603191 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 4,726E-03 0,0458463 ! activation of protein kinase activity GO:0032147 147 79 1,000 4,968E-03 0,04800069 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 4,968E-03 0,04780869 ! muscle cell differentiation GO:0042692 159 80 1,000 5,091E-03 0,04879837 ! protein import into nucleus GO:0006606 158 80 1,000 5,091E-03 0,04860473 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 5,215E-03 0,04959676 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 5,215E-03 0,04940149 ! nuclear import GO:0051170 161 81 1,000 5,215E-03 0,04920776 ! cholesterol metabolic process GO:0008203 136 82 1,000 5,341E-03 0,05019894 ! response to nutrient GO:0007584 125 82 1,000 5,341E-03 0,05000362 ! response to oxygen levels GO:0070482 176 83 1,000 5,469E-03 0,05099702 ! negative regulation of growth GO:0045926 155 84 1,000 5,597E-03 0,05199566 ! positive regulation of cell activation GO:0050867 145 85 1,000 5,727E-03 0,05299944 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 5,859E-03 0,05400827 ! mitochondrion organization GO:0007005 148 86 1,000 5,859E-03 0,05380213 ! protein localization in nucleus GO:0034504 176 87 1,000 5,992E-03 0,05481285 ! gland development GO:0048732 206 88 1,000 6,126E-03 0,05582844 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 6,261E-03 0,05684881 ! regulation of cell cycle process GO:0010564 149 90 1,000 6,398E-03 0,05787387 ! sterol metabolic process GO:0016125 152 91 1,000 6,537E-03 0,05890354 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 6,624E-03 0,05946402 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,624E-03 0,05924296 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,624E-03 0,05902355 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,624E-03 0,05880575 ! neuron fate determination GO:0048664 7 5 0,000 6,624E-03 0,05858955 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,624E-03 0,05837493 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,624E-03 0,05816189 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,624E-03 0,05795039 ! polyol transport GO:0015791 12 5 0,000 6,624E-03 0,05774042 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,624E-03 0,05753198 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,624E-03 0,05732503 ! response to superoxide GO:0000303 10 5 0,000 6,624E-03 0,05711956 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,624E-03 0,05691556 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,624E-03 0,05671302 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,624E-03 0,05651191 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,624E-03 0,05631222 ! female meiosis GO:0007143 7 5 0,000 6,624E-03 0,05611393 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,624E-03 0,05591704 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,624E-03 0,05572153 ! cobalt ion transport GO:0006824 11 5 0,000 6,624E-03 0,05552738 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,624E-03 0,05533457 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,624E-03 0,0551431 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,624E-03 0,05495296 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,624E-03 0,05476411 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,624E-03 0,05457657 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,624E-03 0,0543903 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,624E-03 0,0542053 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,624E-03 0,05402155 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,624E-03 0,05383904 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,624E-03 0,05365777 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,624E-03 0,05347771 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,624E-03 0,05329885 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,624E-03 0,05312119 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,624E-03 0,05294471 ! negative chemotaxis GO:0050919 14 5 0,000 6,624E-03 0,05276939 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,624E-03 0,05259524 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,624E-03 0,05242223 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,624E-03 0,05225035 ! behavioral response to pain GO:0048266 9 5 0,000 6,624E-03 0,0520796 ! clathrin coat assembly GO:0048268 14 5 0,000 6,624E-03 0,05190996 ! Notch receptor processing GO:0007220 8 5 0,000 6,624E-03 0,05174142 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,624E-03 0,05157397 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,624E-03 0,0514076 ! micturition GO:0060073 9 5 0,000 6,624E-03 0,05124231 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,624E-03 0,05107807 ! copulation GO:0007620 9 5 0,000 6,624E-03 0,05091488 ! glial cell fate commitment GO:0021781 13 5 0,000 6,624E-03 0,05075273 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,624E-03 0,05059161 ! spermidine metabolic process GO:0008216 7 5 0,000 6,624E-03 0,05043151 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,624E-03 0,05027242 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,624E-03 0,05011433 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,624E-03 0,04995723 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,624E-03 0,04980112 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,624E-03 0,04964597 ! grooming behavior GO:0007625 6 5 0,000 6,624E-03 0,04949179 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,624E-03 0,04933857 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,624E-03 0,04918629 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,624E-03 0,04903495 ! response to protozoan GO:0001562 10 5 0,000 6,624E-03 0,04888453 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,624E-03 0,04873504 ! lymph vessel development GO:0001945 10 5 0,000 6,624E-03 0,04858645 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,624E-03 0,04843878 ! endochondral ossification GO:0001958 16 5 0,000 6,624E-03 0,04829199 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,624E-03 0,04814609 ! parathyroid gland development GO:0060017 13 5 0,000 6,624E-03 0,04800108 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,624E-03 0,04785693 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,624E-03 0,04771364 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 6,624E-03 0,04757122 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,624E-03 0,04742963 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,624E-03 0,04728889 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,624E-03 0,04714899 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,624E-03 0,0470099 ! skeletal myofibril assembly GO:0014866 10 5 0,000 6,624E-03 0,04687164 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,624E-03 0,04673419 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,624E-03 0,04659754 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,624E-03 0,04646168 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,624E-03 0,04632662 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,624E-03 0,04619234 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,624E-03 0,04605884 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,624E-03 0,0459261 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 6,624E-03 0,04579413 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,624E-03 0,04566291 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,624E-03 0,04553245 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,624E-03 0,04540273 ! histidine catabolic process GO:0006548 6 5 0,000 6,624E-03 0,04527374 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,624E-03 0,04514549 ! microvillus organization GO:0032528 7 5 0,000 6,624E-03 0,04501796 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 6,624E-03 0,04489115 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,624E-03 0,04476505 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,624E-03 0,04463966 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,624E-03 0,04451496 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,624E-03 0,04439097 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,624E-03 0,04426766 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,624E-03 0,04414503 ! polyol catabolic process GO:0046174 7 5 0,000 6,624E-03 0,04402309 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,624E-03 0,04390181 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,624E-03 0,0437812 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,624E-03 0,04366125 ! muscle cell migration GO:0014812 8 5 0,000 6,624E-03 0,04354196 ! mitochondrial fission GO:0000266 8 5 0,000 6,624E-03 0,04342332 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,624E-03 0,04330532 ! mRNA transcription GO:0009299 9 5 0,000 6,624E-03 0,04318796 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,624E-03 0,04307124 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,624E-03 0,04295514 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,624E-03 0,04283967 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,624E-03 0,04272482 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,624E-03 0,04261058 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,624E-03 0,04249695 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,624E-03 0,04238393 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,624E-03 0,0422715 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,624E-03 0,04215968 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,624E-03 0,04204844 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,624E-03 0,04193778 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,624E-03 0,04182771 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,624E-03 0,04171821 ! forebrain neuron development GO:0021884 13 5 0,000 6,624E-03 0,04160929 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,624E-03 0,04150093 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,624E-03 0,04139314 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,624E-03 0,0412859 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,624E-03 0,04117922 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,624E-03 0,04107309 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,624E-03 0,0409675 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,624E-03 0,04086245 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,624E-03 0,04075795 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,624E-03 0,04065397 ! basic amino acid transport GO:0015802 11 5 0,000 6,624E-03 0,04055053 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,624E-03 0,04044761 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,624E-03 0,04034521 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,624E-03 0,04024333 ! depyrimidination GO:0045008 10 5 0,000 6,624E-03 0,04014196 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,624E-03 0,0400411 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,624E-03 0,03994074 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,624E-03 0,03984089 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,624E-03 0,03974154 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,624E-03 0,03964268 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,624E-03 0,03954431 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,624E-03 0,03944643 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,624E-03 0,03934903 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,624E-03 0,03925211 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,624E-03 0,03915567 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,624E-03 0,0390597 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,624E-03 0,0389642 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,624E-03 0,03886916 ! response to arsenic GO:0046685 10 5 0,000 6,624E-03 0,03877459 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,624E-03 0,03868048 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,624E-03 0,03858682 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,624E-03 0,03849362 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,624E-03 0,03840086 ! response to cadmium ion GO:0046686 7 5 0,000 6,624E-03 0,03830855 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,624E-03 0,03821668 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,624E-03 0,03812526 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,624E-03 0,03803427 ! decidualization GO:0046697 11 5 0,000 6,624E-03 0,03794371 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,624E-03 0,03785358 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,624E-03 0,03776388 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,624E-03 0,0376746 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,624E-03 0,03758575 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,624E-03 0,03749731 ! base conversion or substitution editing GO:0016553 5 5 0,000 6,624E-03 0,03740929 ! neural tube patterning GO:0021532 7 5 0,000 6,624E-03 0,03732168 ! embryonic cleavage GO:0040016 6 5 0,000 6,624E-03 0,03723448 ! peroxisome fission GO:0016559 5 5 0,000 6,624E-03 0,03714769 ! histone demethylation GO:0016577 10 5 0,000 6,624E-03 0,0370613 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,624E-03 0,03697531 ! mitotic recombination GO:0006312 9 5 0,000 6,624E-03 0,03688972 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,624E-03 0,03680452 ! metaphase plate congression GO:0051310 7 5 0,000 6,624E-03 0,03671972 ! regulation of sterol transport GO:0032371 7 5 0,000 6,624E-03 0,0366353 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,624E-03 0,03655128 ! enteric nervous system development GO:0048484 8 5 0,000 6,624E-03 0,03646764 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,624E-03 0,03638438 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,624E-03 0,0363015 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,624E-03 0,03621899 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,624E-03 0,03613686 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 6,624E-03 0,03605511 ! plasminogen activation GO:0031639 5 5 0,000 6,624E-03 0,03597372 ! B cell homeostasis GO:0001782 13 5 0,000 6,624E-03 0,0358927 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,624E-03 0,03581204 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,624E-03 0,03573174 ! metaphase GO:0051323 8 5 0,000 6,624E-03 0,03565181 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,624E-03 0,03557223 ! cellular response to nutrient GO:0031670 8 5 0,000 6,624E-03 0,035493 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,624E-03 0,03541413 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,624E-03 0,0353356 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,624E-03 0,03525743 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,624E-03 0,0351796 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,624E-03 0,03510211 ! response to redox state GO:0051775 5 5 0,000 6,624E-03 0,03502496 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,624E-03 0,03494815 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,624E-03 0,03487168 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,624E-03 0,03479554 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,624E-03 0,03471973 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,624E-03 0,03464425 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,624E-03 0,0345691 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,624E-03 0,03449428 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,624E-03 0,03441978 ! striatum development GO:0021756 9 5 0,000 6,624E-03 0,0343456 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,624E-03 0,03427174 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 6,624E-03 0,03419819 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,624E-03 0,03412496 ! glial cell migration GO:0008347 11 5 0,000 6,624E-03 0,03405205 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,624E-03 0,03397944 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,624E-03 0,03390714 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,624E-03 0,03383515 ! somatic stem cell maintenance GO:0035019 15 5 0,000 6,624E-03 0,03376347 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,624E-03 0,03369209 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,624E-03 0,03362101 ! neuroprotection GO:0043526 6 5 0,000 6,624E-03 0,03355023 ! neural plate development GO:0001840 8 5 0,000 6,624E-03 0,03347974 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,624E-03 0,03340955 ! regulation of sensory perception GO:0051931 7 5 0,000 6,624E-03 0,03333966 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,624E-03 0,03327006 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,624E-03 0,03320074 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,624E-03 0,03313172 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,624E-03 0,03306298 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,624E-03 0,03299453 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,624E-03 0,03292636 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,624E-03 0,03285847 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,624E-03 0,03279086 ! spindle assembly GO:0051225 6 5 0,000 6,624E-03 0,03272353 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,624E-03 0,03265647 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,624E-03 0,03258969 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,624E-03 0,03252318 ! drug metabolic process GO:0017144 6 5 0,000 6,624E-03 0,03245694 ! stem cell division GO:0017145 11 5 0,000 6,624E-03 0,03239097 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,624E-03 0,03232527 ! organ regeneration GO:0031100 7 5 0,000 6,624E-03 0,03225983 ! carnitine metabolic process GO:0009437 7 5 0,000 6,624E-03 0,03219466 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,624E-03 0,03212975 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,624E-03 0,03206511 ! vitamin metabolic process GO:0006766 139 92 1,000 6,676E-03 0,03225565 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 6,817E-03 0,03287104 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 6,817E-03 0,03280529 ! regulation of membrane potential GO:0042391 164 93 1,000 6,817E-03 0,03273981 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 6,817E-03 0,03267459 ! protein ubiquitination GO:0016567 217 97 1,000 7,395E-03 0,03537262 ! skeletal muscle tissue development GO:0007519 186 99 1,000 7,692E-03 0,03671958 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 1,000 7,842E-03 0,03736355 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,943E-03 0,03776928 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,943E-03 0,03769478 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 7,943E-03 0,03762058 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 7,943E-03 0,03754667 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,943E-03 0,03747305 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 7,943E-03 0,03739972 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 7,943E-03 0,03732667 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,943E-03 0,03725391 ! sleep GO:0030431 13 6 0,000 7,943E-03 0,03718143 ! response to oxygen radical GO:0000305 11 6 0,000 7,943E-03 0,03710923 ! positive regulation of axon extension GO:0045773 11 6 0,000 7,943E-03 0,03703732 ! myoblast cell fate commitment GO:0048625 16 6 0,000 7,943E-03 0,03696568 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 7,943E-03 0,03689432 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 7,943E-03 0,03682323 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,943E-03 0,03675241 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,943E-03 0,03668187 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 7,943E-03 0,0366116 ! forebrain regionalization GO:0021871 8 6 0,000 7,943E-03 0,0365416 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,943E-03 0,03647186 ! male meiosis GO:0007140 7 6 0,000 7,943E-03 0,03640239 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,943E-03 0,03633319 ! response to zinc ion GO:0010043 9 6 0,000 7,943E-03 0,03626424 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,943E-03 0,03619556 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 7,943E-03 0,03612714 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 7,943E-03 0,03605897 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,943E-03 0,03599107 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,943E-03 0,03592341 ! malate metabolic process GO:0006108 11 6 0,000 7,943E-03 0,03585601 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 7,943E-03 0,03578887 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 7,943E-03 0,03572197 ! protein refolding GO:0042026 15 6 0,000 7,943E-03 0,03565533 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,943E-03 0,03558893 ! opsonization GO:0008228 8 6 0,000 7,943E-03 0,03552278 ! mating behavior GO:0007617 7 6 0,000 7,943E-03 0,03545688 ! neuron remodeling GO:0016322 15 6 0,000 7,943E-03 0,03539121 ! erythrocyte maturation GO:0043249 7 6 0,000 7,943E-03 0,0353258 ! embryonic hemopoiesis GO:0035162 14 6 0,000 7,943E-03 0,03526062 ! equilibrioception GO:0050957 14 6 0,000 7,943E-03 0,03519568 ! protein amino acid dealkylation GO:0008214 12 6 0,000 7,943E-03 0,03513098 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 7,943E-03 0,03506652 ! photoreceptor cell development GO:0042461 10 6 0,000 7,943E-03 0,0350023 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 7,943E-03 0,03493831 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,943E-03 0,03487455 ! response to interferon-gamma GO:0034341 15 6 0,000 7,943E-03 0,03481103 ! toxin metabolic process GO:0009404 11 6 0,000 7,943E-03 0,03474774 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,943E-03 0,03468467 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 7,943E-03 0,03462184 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 7,943E-03 0,03455923 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 7,943E-03 0,03449685 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 7,943E-03 0,0344347 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,943E-03 0,03437276 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 7,943E-03 0,03431105 ! thymic T cell selection GO:0045061 12 6 0,000 7,943E-03 0,03424956 ! protein lipoylation GO:0009249 10 6 0,000 7,943E-03 0,03418829 ! cysteine metabolic process GO:0006534 10 6 0,000 7,943E-03 0,03412724 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,943E-03 0,03406641 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 7,943E-03 0,03400579 ! glutamate catabolic process GO:0006538 10 6 0,000 7,943E-03 0,03394539 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 7,943E-03 0,03388521 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 7,943E-03 0,03382523 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 7,943E-03 0,03376547 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 7,943E-03 0,03370592 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,943E-03 0,03364658 ! hyperosmotic response GO:0006972 9 6 0,000 7,943E-03 0,03358744 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 7,943E-03 0,03352852 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 7,943E-03 0,0334698 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,943E-03 0,03341129 ! urea metabolic process GO:0019627 7 6 0,000 7,943E-03 0,03335298 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,943E-03 0,03329487 ! neutrophil activation GO:0042119 8 6 0,000 7,943E-03 0,03323697 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,943E-03 0,03317926 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 7,943E-03 0,03312176 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,943E-03 0,03306446 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 7,943E-03 0,03300735 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,943E-03 0,03295044 ! neuron apoptosis GO:0051402 9 6 0,000 7,943E-03 0,03289373 ! nucleoside salvage GO:0043174 9 6 0,000 7,943E-03 0,03283721 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 7,943E-03 0,03278088 ! T cell mediated immunity GO:0002456 16 6 0,000 7,943E-03 0,03272475 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,943E-03 0,03266881 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 7,943E-03 0,03261306 ! carnitine transport GO:0015879 10 6 0,000 7,943E-03 0,03255751 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 7,943E-03 0,03250214 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,943E-03 0,03244695 ! positive regulation of exocytosis GO:0045921 8 6 0,000 7,943E-03 0,03239196 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 7,943E-03 0,03233715 ! 5S class rRNA transcription GO:0042791 11 6 0,000 7,943E-03 0,03228253 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,943E-03 0,03222809 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 7,943E-03 0,03217383 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 7,943E-03 0,03211976 ! sodium ion homeostasis GO:0055078 11 6 0,000 7,943E-03 0,03206587 ! establishment of spindle localization GO:0051293 12 6 0,000 7,943E-03 0,03201215 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 7,943E-03 0,03195862 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,943E-03 0,03190527 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 7,943E-03 0,03185209 ! neural nucleus development GO:0048857 14 6 0,000 7,943E-03 0,03179909 ! response to UV-C GO:0010225 11 6 0,000 7,943E-03 0,03174627 ! astrocyte development GO:0014002 15 6 0,000 7,943E-03 0,03169362 ! protein targeting to lysosome GO:0006622 10 6 0,000 7,943E-03 0,03164115 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,943E-03 0,03158885 ! interaction with symbiont GO:0051702 13 6 0,000 7,943E-03 0,03153673 ! regulation of dendrite development GO:0050773 16 6 0,000 7,943E-03 0,03148477 ! skeletal muscle contraction GO:0003009 6 6 0,000 7,943E-03 0,03143299 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 7,943E-03 0,03138137 ! response to copper ion GO:0046688 10 6 0,000 7,943E-03 0,03132993 ! response to exogenous dsRNA GO:0043330 10 6 0,000 7,943E-03 0,03127865 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 7,943E-03 0,03122754 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,943E-03 0,0311766 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 7,943E-03 0,03112582 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,943E-03 0,03107521 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 7,943E-03 0,03102477 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,943E-03 0,03097448 ! nucleoside catabolic process GO:0009164 7 6 0,000 7,943E-03 0,03092436 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,943E-03 0,0308744 ! Schwann cell development GO:0014044 15 6 0,000 7,943E-03 0,03082461 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 7,943E-03 0,03077497 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 7,943E-03 0,03072549 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 7,943E-03 0,03067617 ! subpallium development GO:0021544 10 6 0,000 7,943E-03 0,03062701 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 7,943E-03 0,03057801 ! histone ubiquitination GO:0016574 8 6 0,000 7,943E-03 0,03052916 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 7,943E-03 0,03048047 ! maintenance of organ identity GO:0048496 9 6 0,000 7,943E-03 0,03043194 ! G2 phase GO:0051319 16 6 0,000 7,943E-03 0,03038355 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 7,943E-03 0,03033533 ! establishment of planar polarity GO:0001736 7 6 0,000 7,943E-03 0,03028725 ! regulation of mast cell activation GO:0033003 12 6 0,000 7,943E-03 0,03023933 ! membrane to membrane docking GO:0022614 14 6 0,000 7,943E-03 0,03019156 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,943E-03 0,03014394 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 7,943E-03 0,03009647 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,943E-03 0,03004914 ! receptor internalization GO:0031623 10 6 0,000 7,943E-03 0,03000197 ! neutrophil homeostasis GO:0001780 10 6 0,000 7,943E-03 0,02995495 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,943E-03 0,02990807 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 7,943E-03 0,02986134 ! protein deubiquitination GO:0016579 14 6 0,000 7,943E-03 0,02981475 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 7,943E-03 0,02976831 ! protein destabilization GO:0031648 9 6 0,000 7,943E-03 0,02972202 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,943E-03 0,02967586 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 7,943E-03 0,02962985 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 7,943E-03 0,02958399 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 7,943E-03 0,02953826 ! progesterone metabolic process GO:0042448 10 6 0,000 7,943E-03 0,02949268 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 7,943E-03 0,02944724 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 7,943E-03 0,02940193 ! negative regulation of axon extension GO:0030517 21 6 0,000 7,943E-03 0,02935677 ! removal of superoxide radicals GO:0019430 11 6 0,000 7,943E-03 0,02931174 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,943E-03 0,02926685 ! determination of adult lifespan GO:0008340 15 6 0,000 7,943E-03 0,0292221 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 7,943E-03 0,02917749 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 7,943E-03 0,02913301 ! cerebellar cortex formation GO:0021697 8 6 0,000 7,943E-03 0,02908867 ! catecholamine transport GO:0051937 9 6 0,000 7,943E-03 0,02904446 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 7,943E-03 0,02900039 ! sensory cilium assembly GO:0035058 10 6 0,000 7,943E-03 0,02895645 ! organ or tissue specific immune response GO:0002251 7 6 0,000 7,943E-03 0,02891264 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 7,943E-03 0,02886897 ! maternal placenta development GO:0001893 12 6 0,000 7,943E-03 0,02882542 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 7,943E-03 0,02878201 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,943E-03 0,02873873 ! negative regulation of B cell activation GO:0050869 13 6 0,000 7,943E-03 0,02869558 ! protein amino acid prenylation GO:0018346 16 6 0,000 7,943E-03 0,02865256 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 7,943E-03 0,02860966 ! positive regulation of coagulation GO:0050820 12 6 0,000 7,943E-03 0,0285669 ! tRNA transcription GO:0009304 14 7 0,000 9,261E-03 0,03325678 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 9,261E-03 0,03320722 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 9,261E-03 0,0331578 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,261E-03 0,03310853 ! regulation of helicase activity GO:0051095 15 7 0,000 9,261E-03 0,03305941 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 9,261E-03 0,03301043 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 9,261E-03 0,0329616 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,261E-03 0,03291291 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 9,261E-03 0,03286437 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,261E-03 0,03281597 ! prostate gland development GO:0030850 13 7 0,000 9,261E-03 0,03276771 ! nucleotide-sugar transport GO:0015780 12 7 0,000 9,261E-03 0,03271959 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,261E-03 0,03267162 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,261E-03 0,03262378 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 9,261E-03 0,03257609 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,261E-03 0,03252853 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 9,261E-03 0,03248111 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 9,261E-03 0,03243383 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 9,261E-03 0,03238669 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,261E-03 0,03233968 ! SMAD protein complex assembly GO:0007183 12 7 0,000 9,261E-03 0,03229281 ! glycolipid transport GO:0046836 10 7 0,000 9,261E-03 0,03224608 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,261E-03 0,03219948 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 9,261E-03 0,03215302 ! neuron adhesion GO:0007158 12 7 0,000 9,261E-03 0,03210669 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 9,261E-03 0,03206049 ! actin-myosin filament sliding GO:0033275 11 7 0,000 9,261E-03 0,03201443 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 9,261E-03 0,0319685 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 9,261E-03 0,0319227 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 9,261E-03 0,03187703 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 9,261E-03 0,03183149 ! mRNA stabilization GO:0048255 18 7 0,000 9,261E-03 0,03178608 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 9,261E-03 0,0317408 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 9,261E-03 0,03169565 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 9,261E-03 0,03165063 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,261E-03 0,03160573 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,261E-03 0,03156097 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,261E-03 0,03151633 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,261E-03 0,03147181 ! lipoprotein transport GO:0042953 14 7 0,000 9,261E-03 0,03142742 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,261E-03 0,03138316 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,261E-03 0,03133902 ! rhythmic behavior GO:0007622 15 7 0,000 9,261E-03 0,031295 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 9,261E-03 0,03125111 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 9,261E-03 0,03120734 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 9,261E-03 0,0311637 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,261E-03 0,03112017 ! regulation of odontogenesis GO:0042481 13 7 0,000 9,261E-03 0,03107677 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,261E-03 0,03103348 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 9,261E-03 0,03099032 ! mechanosensory behavior GO:0007638 14 7 0,000 9,261E-03 0,03094728 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 9,261E-03 0,03090436 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,261E-03 0,03086155 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 9,261E-03 0,03081887 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,261E-03 0,0307763 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,261E-03 0,03073385 ! spinal cord patterning GO:0021511 13 7 0,000 9,261E-03 0,03069152 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 9,261E-03 0,0306493 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,261E-03 0,0306072 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 9,261E-03 0,03056522 ! adrenal gland development GO:0030325 17 7 0,000 9,261E-03 0,03052335 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 9,261E-03 0,03048159 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 9,261E-03 0,03043995 ! ovulation GO:0030728 9 7 0,000 9,261E-03 0,03039842 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 9,261E-03 0,03035701 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 9,261E-03 0,0303157 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 9,261E-03 0,03027451 ! microtubule nucleation GO:0007020 20 7 0,000 9,261E-03 0,03023344 ! proline biosynthetic process GO:0006561 10 7 0,000 9,261E-03 0,03019247 ! thyroid hormone generation GO:0006590 13 7 0,000 9,261E-03 0,03015161 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 9,261E-03 0,03011087 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 9,261E-03 0,03007023 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,261E-03 0,03002971 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,261E-03 0,02998929 ! galactose metabolic process GO:0006012 13 7 0,000 9,261E-03 0,02994898 ! response to dietary excess GO:0002021 8 7 0,000 9,261E-03 0,02990878 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,261E-03 0,02986869 ! intracellular pH reduction GO:0051452 11 7 0,000 9,261E-03 0,0298287 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,261E-03 0,02978883 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 9,261E-03 0,02974906 ! organ growth GO:0035265 15 7 0,000 9,261E-03 0,02970939 ! purine salvage GO:0043101 10 7 0,000 9,261E-03 0,02966983 ! nucleoside transport GO:0015858 8 7 0,000 9,261E-03 0,02963038 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 9,261E-03 0,02959103 ! parturition GO:0007567 14 7 0,000 9,261E-03 0,02955178 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 9,261E-03 0,02951264 ! rRNA modification GO:0000154 14 7 0,000 9,261E-03 0,0294736 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 9,261E-03 0,02943467 ! spindle checkpoint GO:0031577 15 7 0,000 9,261E-03 0,02939583 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 9,261E-03 0,0293571 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 9,261E-03 0,02931848 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,261E-03 0,02927995 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,261E-03 0,02924153 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 9,261E-03 0,0292032 ! hyaluronan metabolic process GO:0030212 8 7 0,000 9,261E-03 0,02916498 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 9,261E-03 0,02912685 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,261E-03 0,02908883 ! fibrinolysis GO:0042730 10 7 0,000 9,261E-03 0,0290509 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 9,261E-03 0,02901308 ! eating behavior GO:0042755 7 7 0,000 9,261E-03 0,02897535 ! B cell lineage commitment GO:0002326 21 7 0,000 9,261E-03 0,02893772 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,261E-03 0,02890018 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 9,261E-03 0,02886275 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 9,261E-03 0,02882541 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,261E-03 0,02878817 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 9,261E-03 0,02875102 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,261E-03 0,02871397 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 9,261E-03 0,02867702 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 9,261E-03 0,02864016 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 9,261E-03 0,02860339 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 9,261E-03 0,02856672 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,261E-03 0,02853014 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 9,261E-03 0,02849366 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,261E-03 0,02845727 ! regulation of meiosis GO:0040020 12 7 0,000 9,261E-03 0,02842097 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 9,261E-03 0,02838477 ! T cell lineage commitment GO:0002360 16 7 0,000 9,261E-03 0,02834865 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 9,261E-03 0,02831263 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,261E-03 0,0282767 ! oxygen homeostasis GO:0032364 12 7 0,000 9,261E-03 0,02824086 ! transcription termination GO:0006353 13 7 0,000 9,261E-03 0,02820512 ! response to tumor cell GO:0002347 13 7 0,000 9,261E-03 0,02816946 ! regulation of respiratory burst GO:0060263 11 7 0,000 9,261E-03 0,02813389 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,261E-03 0,02809841 ! anaphase GO:0051322 17 7 0,000 9,261E-03 0,02806303 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 9,261E-03 0,02802773 ! axonal fasciculation GO:0007413 18 7 0,000 9,261E-03 0,02799252 ! negative regulation of nuclear division GO:0051784 14 7 0,000 9,261E-03 0,02795739 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 9,261E-03 0,02792236 ! peptidyl-threonine modification GO:0018210 25 7 0,000 9,261E-03 0,02788741 ! diuresis GO:0030146 12 7 0,000 9,261E-03 0,02785255 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,261E-03 0,02781778 ! thiamin metabolic process GO:0006772 7 7 0,000 9,261E-03 0,0277831 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,261E-03 0,0277485 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 9,261E-03 0,02771398 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 9,261E-03 0,02767956 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,261E-03 0,02764521 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,261E-03 0,02761096 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,261E-03 0,02757678 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,261E-03 0,0275427 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 9,261E-03 0,02750869 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,261E-03 0,02747477 ! glycolipid catabolic process GO:0019377 15 7 0,000 9,261E-03 0,02744094 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,261E-03 0,02740719 ! lymph node development GO:0048535 10 7 0,000 9,261E-03 0,02737352 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 9,261E-03 0,02733993 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,261E-03 0,02730642 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 9,261E-03 0,027273 ! endosome to lysosome transport GO:0008333 11 7 0,000 9,261E-03 0,02723966 ! protein modification by small protein removal GO:0070646 16 7 0,000 9,261E-03 0,0272064 ! adult feeding behavior GO:0008343 9 7 0,000 9,261E-03 0,02717322 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 9,261E-03 0,02714012 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 9,261E-03 0,02710711 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,261E-03 0,02707417 ! muscle adaptation GO:0043500 14 7 0,000 9,261E-03 0,02704131 ! embryonic heart tube development GO:0035050 10 7 0,000 9,261E-03 0,02700854 ! retina homeostasis GO:0001895 12 7 0,000 9,261E-03 0,02697584 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 9,261E-03 0,02694322 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 9,261E-03 0,02691068 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 9,261E-03 0,02687822 ! protein prenylation GO:0018342 18 7 0,000 9,261E-03 0,02684583 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,261E-03 0,02681353 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01057719 0,03058741 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01057719 0,03055069 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01057719 0,03051405 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01057719 0,03047751 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01057719 0,03044105 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01057719 0,03040469 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01057719 0,0303684 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01057719 0,03033221 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01057719 0,0302961 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01057719 0,03026007 ! meiotic prophase I GO:0007128 13 8 0,000 0,01057719 0,03022413 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01057719 0,03018828 ! oligopeptide transport GO:0006857 15 8 0,000 0,01057719 0,03015251 ! UTP metabolic process GO:0046051 8 8 0,000 0,01057719 0,03011683 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01057719 0,03008123 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01057719 0,03004572 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01057719 0,03001028 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01057719 0,02997494 ! succinate metabolic process GO:0006105 14 8 0,000 0,01057719 0,02993967 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01057719 0,02990449 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01057719 0,02986939 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01057719 0,02983437 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01057719 0,02979944 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01057719 0,02976459 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01057719 0,02972982 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01057719 0,02969512 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01057719 0,02966051 ! reflex GO:0060004 16 8 0,000 0,01057719 0,02962599 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01057719 0,02959154 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01057719 0,02955717 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01057719 0,02952288 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01057719 0,02948867 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01057719 0,02945454 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01057719 0,02942049 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01057719 0,02938651 ! pigment granule organization GO:0048753 16 8 0,000 0,01057719 0,02935262 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01057719 0,0293188 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01057719 0,02928507 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01057719 0,0292514 ! histidine metabolic process GO:0006547 16 8 0,000 0,01057719 0,02921782 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01057719 0,02918431 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01057719 0,02915088 ! glycine catabolic process GO:0006546 13 8 0,000 0,01057719 0,02911753 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01057719 0,02908425 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01057719 0,02905105 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01057719 0,02901793 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01057719 0,02898488 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01057719 0,0289519 ! melanin metabolic process GO:0006582 15 8 0,000 0,01057719 0,028919 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01057719 0,02888618 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01057719 0,02885343 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01057719 0,02882075 ! macrophage activation GO:0042116 12 8 0,000 0,01057719 0,02878815 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01057719 0,02875562 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01057719 0,02872316 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01057719 0,02869078 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01057719 0,02865847 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01057719 0,02862623 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01057719 0,02859407 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01057719 0,02856198 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01057719 0,02852996 ! osteoblast development GO:0002076 16 8 0,000 0,01057719 0,02849801 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01057719 0,02846613 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01057719 0,02843433 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01057719 0,02840259 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01057719 0,02837093 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01057719 0,02833933 ! response to UV-B GO:0010224 16 8 0,000 0,01057719 0,02830781 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01057719 0,02827636 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01057719 0,02824497 ! intermediate filament organization GO:0045109 12 8 0,000 0,01057719 0,02821366 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01057719 0,02818242 ! cellular extravasation GO:0045123 12 8 0,000 0,01057719 0,02815124 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01057719 0,02812013 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01057719 0,0280891 ! response to antibiotic GO:0046677 11 8 0,000 0,01057719 0,02805813 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01057719 0,02802723 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01057719 0,02799639 ! DNA topological change GO:0006265 12 8 0,000 0,01057719 0,02796563 ! response to tropane GO:0014073 15 8 0,000 0,01057719 0,02793493 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01057719 0,0279043 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01057719 0,02787374 ! melanosome transport GO:0032402 13 8 0,000 0,01057719 0,02784324 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01057719 0,02781281 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01057719 0,02778245 ! mast cell activation GO:0045576 14 8 0,000 0,01057719 0,02775215 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01057719 0,02772192 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01057719 0,02769175 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01057719 0,02766165 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01057719 0,02763162 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01057719 0,02760165 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01057719 0,02757175 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01057719 0,02754191 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01057719 0,02751213 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01057719 0,02748242 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01057719 0,02745277 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01057719 0,02742319 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01057719 0,02739367 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01057719 0,02736422 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01057719 0,02733482 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01057719 0,0273055 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01057719 0,02727623 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01057719 0,02724703 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01057719 0,02721788 ! hormone catabolic process GO:0042447 17 8 0,000 0,01057719 0,02718881 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01057719 0,02715979 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01057719 0,02713083 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01057719 0,02710194 ! ATP catabolic process GO:0006200 11 8 0,000 0,01057719 0,02707311 ! blastocyst growth GO:0001832 19 8 0,000 0,01057719 0,02704434 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01057719 0,02701563 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01057719 0,02698698 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01057719 0,02695839 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01057719 0,02692986 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01057719 0,0269014 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01057719 0,02687299 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01057719 0,02684464 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01057719 0,02681636 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01057719 0,02678813 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01057719 0,02675996 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01057719 0,02673185 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01057719 0,0267038 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01057719 0,02667581 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01057719 0,02664788 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01057719 0,02662 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01057719 0,02659219 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01057719 0,02656443 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01189165 0,02983451 ! axon extension GO:0048675 15 9 0,000 0,01189165 0,02980344 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01189165 0,02977242 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01189165 0,02974148 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01189165 0,02971059 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01189165 0,02967977 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01189165 0,02964901 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01189165 0,02961832 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01189165 0,02958769 ! phosphate transport GO:0006817 19 9 0,000 0,01189165 0,02955713 ! reproductive behavior GO:0019098 19 9 0,000 0,01189165 0,02952662 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01189165 0,02949618 ! CTP metabolic process GO:0046036 9 9 0,000 0,01189165 0,02946581 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01189165 0,02943549 ! GTP metabolic process GO:0046039 9 9 0,000 0,01189165 0,02940524 ! RNA methylation GO:0001510 15 9 0,000 0,01189165 0,02937505 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01189165 0,02934492 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01189165 0,02931486 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01189165 0,02928485 ! artery development GO:0060840 24 9 0,000 0,01189165 0,02925491 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01189165 0,02922502 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01189165 0,0291952 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01189165 0,02916544 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01189165 0,02913574 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01189165 0,0291061 ! chemosensory behavior GO:0007635 20 9 0,000 0,01189165 0,02907652 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01189165 0,029047 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01189165 0,02901754 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01189165 0,02898815 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01189165 0,0289588 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01189165 0,02892952 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01189165 0,0289003 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01189165 0,02887114 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01189165 0,02884204 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01189165 0,02881299 ! protein targeting to ER GO:0045047 22 9 0,000 0,01189165 0,028784 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01189165 0,02875507 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01189165 0,0287262 ! T cell selection GO:0045058 23 9 0,000 0,01189165 0,02869739 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01189165 0,02866864 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01189165 0,02863994 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01189165 0,0286113 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01189165 0,02858272 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01189165 0,02855419 ! mannose metabolic process GO:0006013 13 9 0,000 0,01189165 0,02852572 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01189165 0,02849731 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01189165 0,02846895 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01189165 0,02844066 ! receptor clustering GO:0043113 18 9 0,000 0,01189165 0,02841241 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01189165 0,02838423 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01189165 0,02835609 ! ruffle organization GO:0031529 15 9 0,000 0,01189165 0,02832802 ! retinol metabolic process GO:0042572 18 9 0,000 0,01189165 0,0283 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01189165 0,02827203 ! behavioral fear response GO:0001662 22 9 0,000 0,01189165 0,02824413 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01189165 0,02821627 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01189165 0,02818847 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01189165 0,02816073 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01189165 0,02813304 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01189165 0,0281054 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01189165 0,02807782 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01189165 0,02805029 ! segment specification GO:0007379 13 9 0,000 0,01189165 0,02802282 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01189165 0,0279954 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01189165 0,02796803 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01189165 0,02794072 ! response to amine stimulus GO:0014075 13 9 0,000 0,01189165 0,02791346 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01189165 0,02788626 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01189165 0,0278591 ! erythrocyte development GO:0048821 15 9 0,000 0,01189165 0,027832 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01189165 0,02780496 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01189165 0,02777796 ! renal water homeostasis GO:0003091 14 9 0,000 0,01189165 0,02775102 ! postreplication repair GO:0006301 22 9 0,000 0,01189165 0,02772413 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01189165 0,02769729 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01189165 0,0276705 ! icosanoid secretion GO:0032309 15 9 0,000 0,01189165 0,02764377 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01189165 0,02761708 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01189165 0,02759045 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01189165 0,02756387 ! regulation of cell division GO:0051302 15 9 0,000 0,01189165 0,02753734 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01189165 0,02751086 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01189165 0,02748444 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01189165 0,02745806 ! sterol catabolic process GO:0016127 11 9 0,000 0,01189165 0,02743173 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01189165 0,02740546 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01189165 0,02737923 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01189165 0,02735306 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01189165 0,02732693 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01189165 0,02730086 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01189165 0,02727483 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01189165 0,02724886 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01189165 0,02722293 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01189165 0,02719705 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01189165 0,02717122 ! purine base metabolic process GO:0006144 21 9 0,000 0,01189165 0,02714545 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01189165 0,02711972 ! pigment granule transport GO:0051904 17 9 0,000 0,01189165 0,02709403 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01189165 0,0270684 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01189165 0,02704282 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01189165 0,02701728 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01189165 0,02699179 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01189165 0,02696635 ! mitochondrion localization GO:0051646 15 9 0,000 0,01189165 0,02694096 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0132044 0,02988691 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0132044 0,02985882 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0132044 0,02983078 ! synapsis GO:0007129 13 10 0,000 0,0132044 0,0298028 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0132044 0,02977486 ! N-glycan processing GO:0006491 20 10 0,000 0,0132044 0,02974699 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0132044 0,02971916 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0132044 0,02969138 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0132044 0,02966366 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0132044 0,02963599 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0132044 0,02960837 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,0132044 0,0295808 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0132044 0,02955328 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0132044 0,02952582 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0132044 0,0294984 ! androgen metabolic process GO:0008209 17 10 0,000 0,0132044 0,02947104 ! phospholipid efflux GO:0033700 16 10 0,000 0,0132044 0,02944373 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0132044 0,02941646 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0132044 0,02938925 ! lung alveolus development GO:0048286 26 10 0,000 0,0132044 0,02936209 ! pathogenesis GO:0009405 13 10 0,000 0,0132044 0,02933498 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0132044 0,02930792 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0132044 0,0292809 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0132044 0,02925394 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0132044 0,02922703 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0132044 0,02920017 ! endoderm development GO:0007492 16 10 0,000 0,0132044 0,02917335 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0132044 0,02914659 ! arginine catabolic process GO:0006527 13 10 0,000 0,0132044 0,02911987 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0132044 0,02909321 ! proline metabolic process GO:0006560 13 10 0,000 0,0132044 0,02906659 ! L-serine metabolic process GO:0006563 18 10 0,000 0,0132044 0,02904002 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0132044 0,0290135 ! V(D)J recombination GO:0033151 28 10 0,000 0,0132044 0,02898703 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0132044 0,0289606 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0132044 0,02893423 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0132044 0,0289079 ! B cell proliferation GO:0042100 18 10 0,000 0,0132044 0,02888162 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0132044 0,02885539 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0132044 0,0288292 ! multicellular organism growth GO:0035264 18 10 0,000 0,0132044 0,02880306 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0132044 0,02877698 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0132044 0,02875093 ! epithelial cell development GO:0002064 20 10 0,000 0,0132044 0,02872494 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0132044 0,02869899 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0132044 0,02867309 ! macroautophagy GO:0016236 17 10 0,000 0,0132044 0,02864723 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0132044 0,02862142 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0132044 0,02859566 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0132044 0,02856995 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,0132044 0,02854428 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0132044 0,02851865 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0132044 0,02849308 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0132044 0,02846755 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0132044 0,02844206 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0132044 0,02841662 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0132044 0,02839122 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0132044 0,02836588 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0132044 0,02834057 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0132044 0,02831531 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0132044 0,0282901 ! response to dsRNA GO:0043331 20 10 0,000 0,0132044 0,02826493 ! DNA ligation GO:0006266 19 10 0,000 0,0132044 0,0282398 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0132044 0,02821473 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0132044 0,02818969 ! melanosome localization GO:0032400 16 10 0,000 0,0132044 0,0281647 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0132044 0,02813975 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0132044 0,02811485 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0132044 0,02808999 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0132044 0,02806518 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0132044 0,02804041 ! mRNA cleavage GO:0006379 17 10 0,000 0,0132044 0,02801568 ! protein sumoylation GO:0016925 15 10 0,000 0,0132044 0,027991 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0132044 0,02796636 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0132044 0,02794176 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0132044 0,02791721 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0132044 0,0278927 ! salivary gland development GO:0007431 27 10 0,000 0,0132044 0,02786823 ! prophase GO:0051324 15 10 0,000 0,0132044 0,0278438 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0132044 0,02781942 ! apical protein localization GO:0045176 15 10 0,000 0,0132044 0,02779508 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0132044 0,02777079 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0132044 0,02774653 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0132044 0,02772232 ! midbrain development GO:0030901 13 10 0,000 0,0132044 0,02769815 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0132044 0,02767402 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0132044 0,02764994 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0132044 0,0276259 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0132044 0,02760189 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0132044 0,02757793 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0132044 0,02755402 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0132044 0,02753014 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,0132044 0,0275063 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,0132044 0,02748251 ! oocyte development GO:0048599 17 10 0,000 0,0132044 0,02745876 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0132044 0,02743504 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0132044 0,02741137 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0132044 0,02738774 ! activation of innate immune response GO:0002218 12 10 0,000 0,0132044 0,02736415 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0132044 0,0273406 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0132044 0,02731709 ! response to nicotine GO:0035094 20 10 0,000 0,0132044 0,02729363 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0132044 0,0272702 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0132044 0,02724681 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0132044 0,02722346 ! localization within membrane GO:0051668 20 10 0,000 0,0132044 0,02720015 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01451545 0,02987525 ! respiratory burst GO:0045730 17 11 0,000 0,01451545 0,02984972 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01451545 0,02982423 ! neuron fate specification GO:0048665 17 11 0,000 0,01451545 0,02979878 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01451545 0,02977338 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01451545 0,02974802 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01451545 0,0297227 ! thyroid gland development GO:0030878 26 11 0,000 0,01451545 0,02969742 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01451545 0,02967219 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01451545 0,029647 ! response to pain GO:0048265 24 11 0,000 0,01451545 0,02962186 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01451545 0,02959675 ! T cell proliferation GO:0042098 26 11 0,000 0,01451545 0,02957169 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01451545 0,02954668 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01451545 0,0295217 ! bone resorption GO:0045453 16 11 0,000 0,01451545 0,02949677 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01451545 0,02947187 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01451545 0,02944702 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01451545 0,02942222 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01451545 0,02939745 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01451545 0,02937273 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01451545 0,02934804 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01451545 0,0293234 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01451545 0,0292988 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01451545 0,02927424 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01451545 0,02924972 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01451545 0,02922525 ! lipid digestion GO:0044241 18 11 0,000 0,01451545 0,02920081 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01451545 0,02917642 ! UV protection GO:0009650 19 11 0,000 0,01451545 0,02915206 ! adult heart development GO:0007512 14 11 0,000 0,01451545 0,02912775 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01451545 0,02910348 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01451545 0,02907924 ! temperature homeostasis GO:0001659 17 11 0,000 0,01451545 0,02905505 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01451545 0,0290309 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01451545 0,02900679 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01451545 0,02898271 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01451545 0,02895868 ! regulation of organ growth GO:0046620 13 11 0,000 0,01451545 0,02893469 ! pigment granule localization GO:0051875 20 11 0,000 0,01451545 0,02891074 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01451545 0,02888682 ! vasoconstriction GO:0042310 18 11 0,000 0,01451545 0,02886295 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01451545 0,02883912 ! embryonic axis specification GO:0000578 18 11 0,000 0,01451545 0,02881532 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01451545 0,02879157 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01451545 0,02876785 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01451545 0,02874417 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01451545 0,02872053 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01451545 0,02869694 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01451545 0,02867337 ! zymogen activation GO:0031638 15 11 0,000 0,01451545 0,02864985 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01451545 0,02862637 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01451545 0,02860292 ! nucleosome positioning GO:0016584 15 11 0,000 0,01451545 0,02857952 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01451545 0,02855615 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01451545 0,02853282 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01451545 0,02850953 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01451545 0,02848627 ! acid secretion GO:0046717 18 11 0,000 0,01451545 0,02846306 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01451545 0,02843988 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01451545 0,02841674 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01451545 0,02839363 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01451545 0,02837057 ! oocyte differentiation GO:0009994 18 11 0,000 0,01451545 0,02834754 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01451545 0,02832455 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01451545 0,0283016 ! cholesterol efflux GO:0033344 19 11 0,000 0,01451545 0,02827868 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01451545 0,0282558 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01451545 0,02823296 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01451545 0,02821015 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01451545 0,02818739 ! embryonic gut development GO:0048566 15 11 0,000 0,01451545 0,02816465 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01451545 0,02814196 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01451545 0,0281193 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01451545 0,02809668 ! defense response to fungus GO:0050832 13 11 0,000 0,01451545 0,02807409 ! developmental induction GO:0031128 19 11 0,000 0,01451545 0,02805154 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01451545 0,02802903 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01451545 0,02800655 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01451545 0,02798411 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01451545 0,02796171 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01451545 0,02793934 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01451545 0,027917 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01451545 0,0278947 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0158248 0,03038665 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0158248 0,03036242 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0158248 0,03033823 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0158248 0,03031407 ! virus-host interaction GO:0019048 29 12 0,000 0,0158248 0,03028995 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0158248 0,03026588 ! cartilage condensation GO:0001502 20 12 0,000 0,0158248 0,03024184 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0158248 0,03021784 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0158248 0,03019387 ! protein complex disassembly GO:0043241 27 12 0,000 0,0158248 0,03016995 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0158248 0,03014606 ! hippocampus development GO:0021766 26 12 0,000 0,0158248 0,03012221 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0158248 0,0300984 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0158248 0,03007462 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0158248 0,03005089 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0158248 0,03002719 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0158248 0,03000353 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0158248 0,0299799 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0158248 0,02995631 ! drug transport GO:0015893 16 12 0,000 0,0158248 0,02993276 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0158248 0,02990925 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0158248 0,02988577 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0158248 0,02986233 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0158248 0,02983893 ! focal adhesion formation GO:0048041 35 12 0,000 0,0158248 0,02981556 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0158248 0,02979223 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0158248 0,02976894 ! forebrain cell migration GO:0021885 21 12 0,000 0,0158248 0,02974568 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0158248 0,02972246 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0158248 0,02969928 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0158248 0,02967613 ! fear response GO:0042596 26 12 0,000 0,0158248 0,02965302 ! monoamine transport GO:0015844 18 12 0,000 0,0158248 0,02962994 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0158248 0,0296069 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0158248 0,0295839 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0158248 0,02956093 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0158248 0,02953799 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0158248 0,0295151 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0158248 0,02949223 ! protein homotetramerization GO:0051289 21 12 0,000 0,0158248 0,02946941 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0158248 0,02944662 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0158248 0,02942386 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0158248 0,02940114 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0158248 0,02937845 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0158248 0,0293558 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0158248 0,02933318 ! fucose catabolic process GO:0019317 22 12 0,000 0,0158248 0,0293106 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0158248 0,02928806 ! histone acetylation GO:0016573 26 12 0,000 0,0158248 0,02926554 ! histone methylation GO:0016571 26 12 0,000 0,0158248 0,02924307 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0158248 0,02922062 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0158248 0,02919822 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0158248 0,02917584 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0158248 0,0291535 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0158248 0,0291312 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0158248 0,02910892 ! spleen development GO:0048536 22 12 0,000 0,0158248 0,02908669 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0158248 0,02906448 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0158248 0,02904231 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0158248 0,02902018 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0158248 0,02899808 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0158248 0,02897601 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0158248 0,02895397 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0158248 0,02893197 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0158248 0,02891 ! response to cold GO:0009409 17 12 0,000 0,0158248 0,02888807 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0158248 0,02886617 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0158248 0,0288443 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01713246 0,03120416 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01713246 0,03118056 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01713246 0,03115699 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01713246 0,03113346 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01713246 0,03110996 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01713246 0,0310865 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01713246 0,03106307 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01713246 0,03103968 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01713246 0,03101632 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01713246 0,030993 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01713246 0,03096972 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01713246 0,03094647 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01713246 0,03092325 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01713246 0,03090007 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01713246 0,03087693 ! methionine metabolic process GO:0006555 27 13 0,000 0,01713246 0,03085381 ! plasma membrane organization GO:0007009 24 13 0,000 0,01713246 0,03083074 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01713246 0,03080769 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01713246 0,03078469 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01713246 0,03076171 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01713246 0,03073877 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01713246 0,03071587 ! response to X-ray GO:0010165 25 13 0,000 0,01713246 0,030693 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01713246 0,03067016 ! exocrine system development GO:0035272 32 13 0,000 0,01713246 0,03064736 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01713246 0,03062459 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01713246 0,03060185 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01713246 0,03057915 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01713246 0,03055648 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01713246 0,03053385 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01713246 0,03051125 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01713246 0,03048868 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01713246 0,03046615 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01713246 0,03044365 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01713246 0,03042118 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01713246 0,03039874 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01713246 0,03037634 ! ribosome assembly GO:0042255 17 13 0,000 0,01713246 0,03035397 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01713246 0,03033164 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01713246 0,03030934 ! chromatin silencing GO:0006342 26 13 0,000 0,01713246 0,03028707 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01713246 0,03026483 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01713246 0,03024262 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01713246 0,03022045 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01713246 0,03019831 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01713246 0,0301762 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01713246 0,03015413 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01713246 0,03013209 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01713246 0,03011008 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01713246 0,0300881 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01713246 0,03006615 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01713246 0,03004424 ! embryonic placenta development GO:0001892 23 13 0,000 0,01713246 0,03002236 ! insulin secretion GO:0030073 23 13 0,000 0,01713246 0,03000051 ! actin filament polymerization GO:0030041 24 13 0,000 0,01713246 0,02997869 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01713246 0,0299569 ! acrosome reaction GO:0007340 18 13 0,000 0,01713246 0,02993515 ! rRNA transcription GO:0009303 25 14 0,000 0,01843842 0,03219364 ! lactation GO:0007595 26 14 0,000 0,01843842 0,0321703 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01843842 0,03214699 ! reproductive cellular process GO:0048610 20 14 0,000 0,01843842 0,03212371 ! tRNA modification GO:0006400 20 14 0,000 0,01843842 0,03210046 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01843842 0,03207725 ! regulation of S phase GO:0033261 23 14 0,000 0,01843842 0,03205408 ! water transport GO:0006833 21 14 0,000 0,01843842 0,03203093 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01843842 0,03200782 ! non-recombinational repair GO:0000726 25 14 0,000 0,01843842 0,03198475 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01843842 0,0319617 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01843842 0,03193869 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01843842 0,03191571 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01843842 0,03189277 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01843842 0,03186986 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01843842 0,03184698 ! palate development GO:0060021 31 14 0,000 0,01843842 0,03182413 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01843842 0,03180132 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01843842 0,03177854 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01843842 0,03175579 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01843842 0,03173308 ! arginine metabolic process GO:0006525 17 14 0,000 0,01843842 0,03171039 ! regulation of heart rate GO:0002027 24 14 0,000 0,01843842 0,03168774 ! organic alcohol transport GO:0015850 29 14 0,000 0,01843842 0,03166513 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01843842 0,03164254 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01843842 0,03161999 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01843842 0,03159747 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01843842 0,03157498 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01843842 0,03155252 ! L-amino acid transport GO:0015807 30 14 0,000 0,01843842 0,03153009 ! bone mineralization GO:0030282 17 14 0,000 0,01843842 0,0315077 ! stem cell development GO:0048864 43 14 0,000 0,01843842 0,03148534 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01843842 0,03146301 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01843842 0,03144071 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01843842 0,03141844 ! cerebellum development GO:0021549 21 14 0,000 0,01843842 0,03139621 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01843842 0,031374 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01843842 0,03135183 ! response to gamma radiation GO:0010332 28 14 0,000 0,01843842 0,03132969 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01843842 0,03130758 ! cofactor transport GO:0051181 26 14 0,000 0,01843842 0,0312855 ! NADP metabolic process GO:0006739 24 14 0,000 0,01843842 0,03126345 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01843842 0,03124144 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01843842 0,03121945 ! intestinal absorption GO:0050892 25 14 0,000 0,01843842 0,0311975 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01843842 0,03117557 ! oxygen transport GO:0015671 21 14 0,000 0,01843842 0,03115368 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01843842 0,03113182 ! male genitalia development GO:0030539 24 14 0,000 0,01843842 0,03110999 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01843842 0,03108819 ! regulation of axon extension GO:0030516 37 14 0,000 0,01843842 0,03106642 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01843842 0,03104468 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01843842 0,03102297 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01974269 0,03319421 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01974269 0,03317103 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01974269 0,03314788 ! superoxide anion generation GO:0042554 20 15 0,000 0,01974269 0,03312477 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01974269 0,03310168 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01974269 0,03307863 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01974269 0,03305561 ! copper ion transport GO:0006825 20 15 0,000 0,01974269 0,03303263 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01974269 0,03300967 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01974269 0,03298675 ! sulfate transport GO:0008272 23 15 0,000 0,01974269 0,03296386 ! response to cAMP GO:0051591 22 15 0,000 0,01974269 0,032941 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01974269 0,03291817 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01974269 0,03289537 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01974269 0,03287261 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01974269 0,03284987 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01974269 0,03282717 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01974269 0,0328045 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01974269 0,03278186 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01974269 0,03275925 ! pituitary gland development GO:0021983 29 15 0,000 0,01974269 0,03273668 ! vesicle coating GO:0006901 33 15 0,000 0,01974269 0,03271413 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01974269 0,03269162 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01974269 0,03266913 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01974269 0,03264668 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01974269 0,03262426 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01974269 0,03260187 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01974269 0,0325795 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01974269 0,03255717 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01974269 0,03253487 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01974269 0,03251261 ! histone deacetylation GO:0016575 20 15 0,000 0,01974269 0,03249037 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01974269 0,03246816 ! tissue regeneration GO:0042246 26 15 0,000 0,01974269 0,03244598 ! water homeostasis GO:0030104 27 15 0,000 0,01974269 0,03242383 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01974269 0,03240172 ! muscle maintenance GO:0046716 26 15 0,000 0,01974269 0,03237963 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01974269 0,03235757 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01974269 0,03233555 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01974269 0,03231355 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01974269 0,03229158 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01974269 0,03226965 ! cell killing GO:0001906 29 15 0,000 0,01974269 0,03224774 ! detection of bacterium GO:0016045 18 15 0,000 0,01974269 0,03222586 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01974269 0,03220401 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01974269 0,03218219 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01974269 0,0321604 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01974269 0,03213865 ! peptide hormone processing GO:0016486 23 15 0,000 0,01974269 0,03211692 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02104527 0,03421279 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02104527 0,03418969 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02104527 0,03416662 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02104527 0,03414358 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02104527 0,03412057 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02104527 0,03409759 ! bone remodeling GO:0046849 27 16 0,000 0,02104527 0,03407465 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02104527 0,03405173 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02104527 0,03402885 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02104527 0,034006 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02104527 0,03398317 ! startle response GO:0001964 28 16 0,000 0,02104527 0,03396038 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02104527 0,03393762 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02104527 0,03391489 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02104527 0,03389219 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02104527 0,03386952 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02104527 0,03384688 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02104527 0,03382427 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02104527 0,03380169 ! response to osmotic stress GO:0006970 25 16 0,000 0,02104527 0,03377914 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02104527 0,03375662 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02104527 0,03373413 ! fructose metabolic process GO:0006000 25 16 0,000 0,02104527 0,03371167 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02104527 0,03368924 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02104527 0,03366684 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02104527 0,03364447 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02104527 0,03362213 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02104527 0,03359982 ! axon cargo transport GO:0008088 43 16 0,000 0,02104527 0,03357754 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02104527 0,03355529 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02104527 0,03353306 ! DNA replication initiation GO:0006270 27 16 0,000 0,02104527 0,03351087 ! neuron recognition GO:0008038 35 16 0,000 0,02104527 0,03348871 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02104527 0,03346657 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02104527 0,03344447 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02104527 0,03342239 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02104527 0,03340035 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02104527 0,03337833 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02104527 0,03335634 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02104527 0,03333438 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02104527 0,03331245 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02104527 0,03329055 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02104527 0,03326868 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02104527 0,03324683 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02104527 0,03322502 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02104527 0,03320323 ! defense response to virus GO:0051607 37 16 0,000 0,02104527 0,03318147 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02234617 0,03520948 ! metencephalon development GO:0022037 30 17 0,000 0,02234617 0,03518644 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02234617 0,03516342 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02234617 0,03514044 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02234617 0,03511749 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02234617 0,03509457 ! signal complex assembly GO:0007172 41 17 0,000 0,02234617 0,03507167 ! endothelial cell migration GO:0043542 28 17 0,000 0,02234617 0,03504881 ! inositol metabolic process GO:0006020 28 17 0,000 0,02234617 0,03502598 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02234617 0,03500317 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02234617 0,0349804 ! glial cell development GO:0021782 27 17 0,000 0,02234617 0,03495766 ! limbic system development GO:0021761 36 17 0,000 0,02234617 0,03493494 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02234617 0,03491226 ! adult walking behavior GO:0007628 33 17 0,000 0,02234617 0,0348896 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02234617 0,03486698 ! heart looping GO:0001947 30 17 0,000 0,02234617 0,03484438 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02234617 0,03482181 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02234617 0,03479927 ! myoblast differentiation GO:0045445 45 17 0,000 0,02234617 0,03477676 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02234617 0,03475428 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02234617 0,03473183 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02234617 0,03470941 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02234617 0,03468702 ! glycine metabolic process GO:0006544 28 17 0,000 0,02234617 0,03466465 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02234617 0,03464232 ! NAD metabolic process GO:0019674 29 17 0,000 0,02234617 0,03462001 ! membrane budding GO:0006900 37 17 0,000 0,02234617 0,03459773 ! DNA integration GO:0015074 29 17 0,000 0,02234617 0,03457548 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02234617 0,03455326 ! regulation of protein binding GO:0043393 33 17 0,000 0,02234617 0,03453107 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02234617 0,03450891 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02234617 0,03448677 ! genitalia development GO:0048806 30 17 0,000 0,02234617 0,03446466 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02234617 0,03444259 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02234617 0,03442054 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02234617 0,03439851 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02234617 0,03437652 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02234617 0,03435455 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02234617 0,03433262 ! steroid catabolic process GO:0006706 31 17 0,000 0,02234617 0,03431071 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02234617 0,03428882 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02234617 0,03426697 ! gas transport GO:0015669 25 17 0,000 0,02234617 0,03424514 ! organic cation transport GO:0015695 31 17 0,000 0,02234617 0,03422335 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02234617 0,03420158 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02234617 0,03417983 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02234617 0,03415812 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02234617 0,03413643 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02234617 0,03411477 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02364537 0,03607531 ! neuron maturation GO:0042551 42 18 0,000 0,02364537 0,03605245 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02364537 0,03602962 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02364537 0,03600682 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02364537 0,03598404 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02364537 0,0359613 ! memory GO:0007613 31 18 0,000 0,02364537 0,03593858 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02364537 0,03591589 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02364537 0,03589323 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02364537 0,0358706 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02364537 0,035848 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02364537 0,03582542 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02364537 0,03580288 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02364537 0,03578036 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02364537 0,03575787 ! response to fungus GO:0009620 21 18 0,000 0,02364537 0,03573541 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02364537 0,03571298 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02364537 0,03569057 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02364537 0,03566819 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02364537 0,03564585 ! vitamin transport GO:0051180 27 18 0,000 0,02364537 0,03562353 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02364537 0,03560123 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02364537 0,03557897 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02364537 0,03555673 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02364537 0,03553452 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02364537 0,03551234 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02364537 0,03549019 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02364537 0,03546806 ! protein secretion GO:0009306 39 19 0,000 0,0249429 0,03739104 ! positive regulation of translation GO:0045727 30 19 0,000 0,0249429 0,03736775 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0249429 0,0373445 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0249429 0,03732128 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0249429 0,03729808 ! skin development GO:0043588 36 19 0,000 0,0249429 0,03727492 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0249429 0,03725178 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0249429 0,03722867 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0249429 0,03720559 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0249429 0,03718254 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0249429 0,03715951 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0249429 0,03713652 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0249429 0,03711355 ! cerebral cortex development GO:0021987 36 19 0,000 0,0249429 0,03709061 ! pigmentation during development GO:0048066 41 19 0,000 0,0249429 0,0370677 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0249429 0,03704482 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,0249429 0,03702197 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0249429 0,03699915 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0249429 0,03697635 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0249429 0,03695358 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0249429 0,03693084 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0249429 0,03690813 ! peptide cross-linking GO:0018149 37 19 0,000 0,0249429 0,03688544 ! protein export from nucleus GO:0006611 36 19 0,000 0,0249429 0,03686278 ! heart process GO:0003015 30 19 0,000 0,0249429 0,03684016 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0249429 0,03681755 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,0249429 0,03679498 ! cellular pigmentation GO:0033059 36 19 0,000 0,0249429 0,03677244 ! G1 phase GO:0051318 40 19 0,000 0,0249429 0,03674992 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0249429 0,03672743 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0249429 0,03670496 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0249429 0,03668253 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0249429 0,03666012 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0249429 0,03663774 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0249429 0,03661538 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0249429 0,03659306 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0249429 0,03657076 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0249429 0,03654849 ! cilium assembly GO:0042384 37 19 0,000 0,0249429 0,03652624 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0249429 0,03650402 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02623874 0,03837715 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02623874 0,03835383 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02623874 0,03833055 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02623874 0,03830729 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02623874 0,03828406 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02623874 0,03826086 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02623874 0,03823768 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02623874 0,03821454 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02623874 0,03819142 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02623874 0,03816833 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02623874 0,03814526 ! response to alkaloid GO:0043279 38 20 0,000 0,02623874 0,03812223 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02623874 0,03809922 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02623874 0,03807624 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02623874 0,03805329 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02623874 0,03803037 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02623874 0,03800747 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02623874 0,0379846 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02623874 0,03796176 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02623874 0,03793895 ! body fluid secretion GO:0007589 31 20 0,000 0,02623874 0,03791616 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02623874 0,0378934 ! peptide secretion GO:0002790 35 20 0,000 0,02623874 0,03787067 ! stem cell differentiation GO:0048863 53 20 0,000 0,02623874 0,03784797 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02623874 0,03782529 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02623874 0,03780264 ! sensory perception of pain GO:0019233 30 20 0,000 0,02623874 0,03778002 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02623874 0,03775742 ! diencephalon development GO:0021536 34 20 0,000 0,02623874 0,03773485 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02623874 0,03771231 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02623874 0,0376898 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02623874 0,03766731 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02623874 0,03764485 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02623874 0,03762241 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02623874 0,03760001 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02623874 0,03757763 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02623874 0,03755527 ! regulation of glucose import GO:0046324 29 20 0,000 0,02623874 0,03753294 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02623874 0,03751064 ! actin filament-based movement GO:0030048 43 20 0,000 0,02623874 0,03748837 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02623874 0,03746612 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02623874 0,0374439 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02623874 0,0374217 ! negative regulation of translation GO:0017148 29 20 0,000 0,02623874 0,03739953 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02623874 0,03737739 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02623874 0,03735527 ! regulation of cell killing GO:0031341 42 21 0,000 0,02753291 0,03917455 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02753291 0,0391514 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02753291 0,03912828 ! hormone secretion GO:0046879 38 21 0,000 0,02753291 0,03910518 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02753291 0,03908211 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02753291 0,03905906 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02753291 0,03903605 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02753291 0,03901306 ! axis specification GO:0009798 38 21 0,000 0,02753291 0,03899009 ! ovarian follicle development GO:0001541 35 21 0,000 0,02753291 0,03896716 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02753291 0,03894425 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02753291 0,03892137 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02753291 0,03889851 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02753291 0,03887569 ! cell aging GO:0007569 44 21 0,000 0,02753291 0,03885289 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02753291 0,03883011 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02753291 0,03880736 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02753291 0,03878464 ! cytolysis GO:0019835 24 21 0,000 0,02753291 0,03876195 ! vasodilation GO:0042311 39 21 0,000 0,02753291 0,03873928 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02753291 0,03871664 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02753291 0,03869402 ! oogenesis GO:0048477 36 21 0,000 0,02753291 0,03867144 ! DNA modification GO:0006304 34 21 0,000 0,02753291 0,03864887 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02753291 0,03862634 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02753291 0,03860383 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02753291 0,03858135 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,02753291 0,03855889 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02753291 0,03853646 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02753291 0,03851405 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02753291 0,03849167 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02753291 0,03846932 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02753291 0,03844699 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02753291 0,03842469 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02753291 0,03840242 ! collagen catabolic process GO:0030574 28 21 0,000 0,02753291 0,03838017 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02753291 0,03835794 ! gut development GO:0048565 39 21 0,000 0,02753291 0,03833575 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02882539 0,04011214 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02882539 0,04008896 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02882539 0,0400658 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02882539 0,04004266 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02882539 0,04001956 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02882539 0,03999648 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02882539 0,03997343 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02882539 0,0399504 ! regeneration GO:0031099 41 22 0,000 0,02882539 0,0399274 ! keratinization GO:0031424 28 22 0,000 0,02882539 0,03990443 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02882539 0,03988148 ! sensory perception of taste GO:0050909 28 22 0,000 0,02882539 0,03985856 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02882539 0,03983567 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02882539 0,0398128 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02882539 0,03978996 ! vacuolar transport GO:0007034 36 22 0,000 0,02882539 0,03976714 ! lysosome organization GO:0007040 41 22 0,000 0,02882539 0,03974435 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02882539 0,03972159 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02882539 0,03969885 ! fucose metabolic process GO:0006004 39 22 0,000 0,02882539 0,03967614 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02882539 0,03965346 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02882539 0,0396308 ! ureteric bud development GO:0001657 43 22 0,000 0,02882539 0,03960816 ! renal system process GO:0003014 41 22 0,000 0,02882539 0,03958556 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02882539 0,03956297 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02882539 0,03954042 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02882539 0,03951789 ! sarcomere organization GO:0045214 30 22 0,000 0,02882539 0,03949538 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02882539 0,0394729 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02882539 0,03945045 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02882539 0,03942802 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02882539 0,03940562 ! protein stabilization GO:0050821 39 22 0,000 0,02882539 0,03938324 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,0301162 0,04112349 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0301162 0,04110016 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,0301162 0,04107686 ! gluconeogenesis GO:0006094 33 23 0,000 0,0301162 0,04105359 ! viral genome replication GO:0019079 41 23 0,000 0,0301162 0,04103034 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0301162 0,04100712 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0301162 0,04098393 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0301162 0,04096076 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0301162 0,04093762 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0301162 0,0409145 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0301162 0,04089142 ! visual behavior GO:0007632 42 23 0,000 0,0301162 0,04086835 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0301162 0,04084531 ! response to ethanol GO:0045471 46 23 0,000 0,0301162 0,0408223 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0301162 0,04079932 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,0301162 0,04077636 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0301162 0,04075342 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0301162 0,04073052 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0301162 0,04070763 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0301162 0,04068478 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,0301162 0,04066195 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0301162 0,04063914 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0301162 0,04061636 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0301162 0,04059361 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0301162 0,04057088 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0301162 0,04054817 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0301162 0,0405255 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0301162 0,04050284 ! fatty acid transport GO:0015908 44 23 0,000 0,0301162 0,04048022 ! platelet activation GO:0030168 37 23 0,000 0,0301162 0,04045761 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0301162 0,04043504 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0301162 0,04041249 ! hormone transport GO:0009914 40 23 0,000 0,0301162 0,04038996 ! cell-cell recognition GO:0009988 25 23 0,000 0,0301162 0,04036746 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0301162 0,04034498 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0301162 0,04032253 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0301162 0,0403001 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0301162 0,0402777 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0301162 0,04025533 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03140534 0,04195517 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03140534 0,04193188 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03140534 0,04190863 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03140534 0,0418854 ! spinal cord development GO:0021510 47 24 0,000 0,03140534 0,04186219 ! vacuole organization GO:0007033 43 24 0,000 0,03140534 0,04183901 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03140534 0,04181586 ! digestive system process GO:0022600 39 24 0,000 0,03140534 0,04179273 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03140534 0,04176963 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03140534 0,04174655 ! regulation of behavior GO:0050795 43 24 0,000 0,03140534 0,0417235 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03140534 0,04170047 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03140534 0,04167747 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03140534 0,0416545 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03140534 0,04163155 ! pallium development GO:0021543 49 24 0,000 0,03140534 0,04160862 ! pentose metabolic process GO:0019321 35 24 0,000 0,03140534 0,04158572 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03140534 0,04156285 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03140534 0,04154 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03140534 0,04151717 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03140534 0,04149437 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03140534 0,0414716 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03140534 0,04144885 ! regulation of amine transport GO:0051952 40 24 0,000 0,03140534 0,04142613 ! protein tetramerization GO:0051262 52 24 0,000 0,03140534 0,04140343 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03269281 0,04307717 ! myelination GO:0042552 45 25 0,000 0,03269281 0,04305359 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03269281 0,04303004 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03269281 0,04300651 ! phototransduction GO:0007602 33 25 0,000 0,03269281 0,04298301 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03269281 0,04295953 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03269281 0,04293608 ! sperm motility GO:0030317 31 25 0,000 0,03269281 0,04291266 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03269281 0,04288926 ! receptor metabolic process GO:0043112 46 25 0,000 0,03269281 0,04286589 ! chromosome condensation GO:0030261 45 25 0,000 0,03269281 0,04284254 ! response to starvation GO:0042594 42 25 0,000 0,03269281 0,04281922 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03269281 0,04279592 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,03269281 0,04277265 ! neural crest cell development GO:0014032 54 25 0,000 0,03269281 0,0427494 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03269281 0,04272618 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03269281 0,04270299 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03269281 0,04267982 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03269281 0,04265667 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03269281 0,04263355 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03269281 0,04261046 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03269281 0,04258739 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03269281 0,04256434 ! immunoglobulin production GO:0002377 55 25 0,000 0,03269281 0,04254132 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03269281 0,04251833 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03269281 0,04249536 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03269281 0,04247241 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03269281 0,04244949 ! telomere organization GO:0032200 43 25 0,000 0,03269281 0,04242659 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03269281 0,04240372 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03269281 0,04238088 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03397861 0,04402398 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03397861 0,04400029 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03397861 0,04397662 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03397861 0,04395298 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03397861 0,04392936 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03397861 0,04390577 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03397861 0,0438822 ! tube lumen formation GO:0035148 50 26 0,000 0,03397861 0,04385866 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03397861 0,04383514 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03397861 0,04381165 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03397861 0,04378818 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03397861 0,04376474 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03397861 0,04374133 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03397861 0,04371794 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03397861 0,04369457 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03397861 0,04367123 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03397861 0,04364791 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03397861 0,04362462 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03397861 0,04360135 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03397861 0,04357811 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03397861 0,0435549 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03397861 0,0435317 ! neuron fate commitment GO:0048663 48 27 0,000 0,03526274 0,04515283 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03526274 0,04512881 ! iron ion transport GO:0006826 59 27 0,000 0,03526274 0,04510482 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03526274 0,04508085 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03526274 0,04505691 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03526274 0,045033 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03526274 0,04500911 ! fat cell differentiation GO:0045444 50 27 0,000 0,03526274 0,04498524 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03526274 0,0449614 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03526274 0,04493759 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03526274 0,0449138 ! autophagy GO:0006914 41 27 0,000 0,03526274 0,04489003 ! male gonad development GO:0008584 44 27 0,000 0,03526274 0,0448663 ! response to toxin GO:0009636 47 27 0,000 0,03526274 0,04484258 ! primary neural tube formation GO:0014020 51 27 0,000 0,03526274 0,04481889 ! base-excision repair GO:0006284 41 27 0,000 0,03526274 0,04479523 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03526274 0,04477159 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03526274 0,04474798 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03526274 0,04472439 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03526274 0,04470082 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03526274 0,04467728 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03526274 0,04465377 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03526274 0,04463028 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03526274 0,04460682 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03654521 0,04620483 ! circadian rhythm GO:0007623 50 28 0,000 0,03654521 0,04618056 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03654521 0,04615632 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03654521 0,0461321 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03654521 0,04610791 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03654521 0,04608374 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,03654521 0,0460596 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03654521 0,04603549 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03654521 0,0460114 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03654521 0,04598733 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03654521 0,0459633 ! synaptogenesis GO:0007416 42 28 0,000 0,03654521 0,04593928 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03654521 0,04591529 ! lipid oxidation GO:0034440 43 28 0,000 0,03654521 0,04589133 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03654521 0,04586739 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03654521 0,04584347 ! translational initiation GO:0006413 65 29 0,000 0,03782602 0,04742543 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03782602 0,04740073 ! regulation of pH GO:0006885 43 29 0,000 0,03782602 0,04737606 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03782602 0,04735141 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03782602 0,04732678 ! catechol metabolic process GO:0009712 54 29 0,000 0,03782602 0,04730219 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03782602 0,04727761 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03782602 0,04725307 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03782602 0,04722854 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03782602 0,04720405 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03782602 0,04717958 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03782602 0,04715513 ! cell fate determination GO:0001709 60 29 0,000 0,03782602 0,04713071 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03782602 0,04710632 ! detection of light stimulus GO:0009583 38 29 0,000 0,03782602 0,04708195 ! tissue homeostasis GO:0001894 48 29 0,000 0,03782602 0,0470576 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,03910517 0,04862379 ! zinc ion transport GO:0006829 45 30 0,000 0,03910517 0,04859867 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03910517 0,04857358 ! cell junction assembly GO:0034329 78 30 0,000 0,03910517 0,04854852 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03910517 0,04852348 ! acute-phase response GO:0006953 49 30 0,000 0,03910517 0,04849847 ! myofibril assembly GO:0030239 47 30 0,000 0,03910517 0,04847348 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03910517 0,04844852 ! phospholipid transport GO:0015914 51 30 0,000 0,03910517 0,04842359 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03910517 0,04839868 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03910517 0,0483738 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,03910517 0,04834894 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03910517 0,0483241 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03910517 0,0482993 ! eye morphogenesis GO:0048592 60 30 0,000 0,03910517 0,04827452 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04038266 0,04982598 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04038266 0,04980045 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04038266 0,04977493 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04038266 0,04974945 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04038266 0,04972399 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04038266 0,04969855 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04038266 0,04967314 ! ovulation cycle process GO:0022602 49 31 0,000 0,04038266 0,04964776 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04038266 0,0496224 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,04038266 0,04959707 ! peptide transport GO:0015833 55 31 0,000 0,04038266 0,04957177 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04038266 0,04954649 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04038266 0,04952124 ! mesoderm formation GO:0001707 69 31 0,000 0,04038266 0,04949601 ! natural killer cell activation GO:0030101 45 31 0,000 0,04038266 0,04947081 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04038266 0,04944563 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04038266 0,04942048 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04038266 0,04939536 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04038266 0,04937026 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04038266 0,04934518 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04165849 0,05087834 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04165849 0,05085252 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04165849 0,05082673 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04165849 0,05080097 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04165849 0,05077524 ! spliceosome assembly GO:0000245 67 32 0,000 0,04165849 0,05074953 ! spindle organization GO:0007051 46 32 0,000 0,04165849 0,05072385 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04165849 0,05069819 ! metanephros development GO:0001656 74 32 0,000 0,04165849 0,05067256 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04165849 0,05064695 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04165849 0,05062137 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04165849 0,05059582 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04165849 0,05057029 ! muscle cell development GO:0055001 49 32 0,000 0,04165849 0,05054479 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04165849 0,05051932 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,04165849 0,05049386 ! ovulation cycle GO:0042698 51 32 0,000 0,04165849 0,05046844 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04165849 0,05044304 ! hindbrain development GO:0030902 61 32 0,000 0,04165849 0,05041767 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04165849 0,05039232 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04165849 0,050367 ! gene silencing GO:0016458 65 32 0,000 0,04165849 0,0503417 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04293267 0,05185542 ! post-embryonic development GO:0009791 69 33 0,000 0,04293267 0,0518294 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04293267 0,05180341 ! protein targeting to membrane GO:0006612 68 33 0,000 0,04293267 0,05177744 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04293267 0,0517515 ! ceramide metabolic process GO:0006672 64 33 0,000 0,04293267 0,05172559 ! formation of primary germ layer GO:0001704 72 33 0,000 0,04293267 0,0516997 ! cell fate specification GO:0001708 52 33 0,000 0,04293267 0,05167383 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04293267 0,051648 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04293267 0,05162219 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04293267 0,0515964 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04293267 0,05157064 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04293267 0,05154491 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04420519 0,05304623 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04420519 0,05301979 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04420519 0,05299337 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04420519 0,05296698 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04420519 0,05294061 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04420519 0,05291428 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04420519 0,05288796 ! mismatch repair GO:0006298 46 34 0,000 0,04420519 0,05286168 ! spermatid development GO:0007286 63 34 0,000 0,04420519 0,05283542 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04420519 0,05280918 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04420519 0,05278297 ! regulation of muscle development GO:0048634 70 35 0,000 0,04547607 0,05427352 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04547607 0,05424662 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04547607 0,05421973 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04547607 0,05419288 ! odontogenesis GO:0042476 66 35 0,000 0,04547607 0,05416605 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04547607 0,05413925 ! female gonad development GO:0008585 58 35 0,000 0,04547607 0,05411247 ! telencephalon development GO:0021537 68 35 0,000 0,04547607 0,05408573 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,04547607 0,054059 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04547607 0,05403231 ! cytokine production GO:0001816 59 35 0,000 0,04547607 0,05400564 ! neural tube formation GO:0001841 67 35 0,000 0,04547607 0,053979 ! vesicle localization GO:0051648 64 35 0,000 0,04547607 0,05395238 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0467453 0,05543085 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0467453 0,05540354 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0467453 0,05537626 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0467453 0,05534901 ! cell junction organization GO:0034330 86 36 0,000 0,0467453 0,05532179 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0467453 0,05529459 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0467453 0,05526742 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0467453 0,05524027 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0467453 0,05521315 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0467453 0,05518606 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0467453 0,05515899 ! aerobic respiration GO:0009060 55 36 0,000 0,0467453 0,05513196 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,0467453 0,05510494 ! embryonic organ development GO:0048568 57 36 0,000 0,0467453 0,05507796 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,0467453 0,055051 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,0467453 0,05502407 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04801288 0,05648851 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04801288 0,0564609 ! meiosis I GO:0007127 65 37 0,000 0,04801288 0,05643332 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04801288 0,05640576 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04801288 0,05637823 ! organic anion transport GO:0015711 68 37 0,000 0,04801288 0,05635073 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04801288 0,05632326 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04801288 0,05629581 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04801288 0,05626839 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04801288 0,05624099 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04801288 0,05621362 ! pigment metabolic process GO:0042440 80 37 0,000 0,04801288 0,05618628 ! spermatid differentiation GO:0048515 66 37 0,000 0,04801288 0,05615897 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04927882 0,05761169 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04927882 0,05758371 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04927882 0,05755575 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04927882 0,05752783 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04927882 0,05749993 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04927882 0,05747205 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04927882 0,05744421 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04927882 0,05741639 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04927882 0,0573886 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04927882 0,05736084 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04927882 0,0573331 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04927882 0,05730539 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04927882 0,0572777 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04927882 0,05725005 ! mRNA catabolic process GO:0006402 71 39 0,000 0,05054312 0,05869052 ! learning GO:0007612 77 39 0,000 0,05054312 0,05866221 ! ear morphogenesis GO:0042471 60 39 0,000 0,05054312 0,05863392 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05054312 0,05860566 ! segmentation GO:0035282 67 39 0,000 0,05054312 0,05857743 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05054312 0,05854923 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05054312 0,05852105 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05054312 0,05849291 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05054312 0,05846478 ! RNA modification GO:0009451 57 39 0,000 0,05054312 0,05843669 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05054312 0,05840862 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,05180578 0,05983904 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05180578 0,05981032 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05180578 0,05978164 ! feeding behavior GO:0007631 59 40 0,000 0,05180578 0,05975298 ! negative regulation of binding GO:0051100 72 40 0,000 0,05180578 0,05972435 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,05180578 0,05969574 ! mesenchymal cell development GO:0014031 87 40 0,000 0,05180578 0,05966717 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05180578 0,05963862 ! maintenance of protein location GO:0045185 91 40 0,000 0,05180578 0,0596101 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,0530668 0,0610319 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,0530668 0,06100274 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,0530668 0,06097361 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,0530668 0,0609445 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,0530668 0,06091543 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,0530668 0,06088638 ! T cell differentiation GO:0030217 81 41 0,000 0,0530668 0,06085736 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,0530668 0,06082836 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,0530668 0,0607994 ! female gamete generation GO:0007292 61 41 0,000 0,0530668 0,06077046 ! polyol metabolic process GO:0019751 66 41 0,000 0,0530668 0,06074155 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,0530668 0,06071266 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,05432619 0,06212396 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,05432619 0,06209445 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,05432619 0,06206497 ! regulation of tube size GO:0035150 71 42 0,000 0,05432619 0,06203551 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,05432619 0,06200608 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,05432619 0,06197668 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,05432619 0,06194731 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,05432619 0,06191796 ! neuron migration GO:0001764 79 42 0,000 0,05432619 0,06188864 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,05432619 0,06185935 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,05558395 0,06326158 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,05558395 0,06323167 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,05558395 0,06320178 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,05558395 0,06317193 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05558395 0,0631421 ! neural tube development GO:0021915 77 43 0,000 0,05558395 0,0631123 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,05558395 0,06308253 ! striated muscle contraction GO:0006941 77 43 0,000 0,05558395 0,06305279 ! phagocytosis GO:0006909 90 43 0,000 0,05558395 0,06302308 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05558395 0,06299339 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05684007 0,06438663 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05684007 0,06435633 ! male sex differentiation GO:0046661 76 44 0,000 0,05684007 0,06432606 ! double-strand break repair GO:0006302 81 44 0,000 0,05684007 0,06429582 ! biopolymer methylation GO:0043414 84 44 0,000 0,05684007 0,0642656 ! B cell differentiation GO:0030183 107 44 0,000 0,05684007 0,06423542 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05684007 0,06420526 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,05684007 0,06417513 ! maintenance of location in cell GO:0051651 97 44 0,000 0,05684007 0,06414503 ! glycolysis GO:0006096 65 45 0,000 0,05809456 0,06553001 ! leukocyte migration GO:0050900 68 45 0,000 0,05809456 0,06549931 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,05809456 0,06546863 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,05809456 0,06543798 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,05809456 0,06540735 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,05809456 0,06537676 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,05809456 0,0653462 ! cell growth GO:0016049 84 45 0,000 0,05809456 0,06531566 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,05934743 0,06669309 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,05934743 0,06666196 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,05934743 0,06663085 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,05934743 0,06659977 ! pigmentation GO:0043473 100 46 0,000 0,05934743 0,06656872 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06059867 0,06794054 ! response to calcium ion GO:0051592 81 47 0,000 0,06059867 0,0679089 ! endosome transport GO:0016197 108 47 0,000 0,06059867 0,06787728 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,06059867 0,0678457 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06059867 0,06781414 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06059867 0,06778261 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06059867 0,06775112 ! JNK cascade GO:0007254 91 47 0,000 0,06059867 0,06771965 ! methylation GO:0032259 90 47 0,000 0,06059867 0,06768821 ! mitochondrial transport GO:0006839 82 48 0,000 0,06184829 0,06905197 ! cellular component disassembly GO:0022411 86 48 0,000 0,06184829 0,06901994 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,06184829 0,06898794 ! activation of caspase activity GO:0006919 84 48 0,000 0,06184829 0,06895597 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,06184829 0,06892403 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,06184829 0,06889212 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,06184829 0,06886024 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06309629 0,07021724 ! regulation of action potential GO:0001508 95 49 0,000 0,06309629 0,07018478 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,06309629 0,07015234 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,06309629 0,07011994 ! regulation of ion transport GO:0043269 77 49 0,000 0,06309629 0,07008757 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06309629 0,07005522 ! peptide metabolic process GO:0006518 76 49 0,000 0,06309629 0,07002291 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06309629 0,06999063 ! endocrine system development GO:0035270 104 49 0,000 0,06309629 0,06995837 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,06309629 0,06992615 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06309629 0,06989396 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06309629 0,06986179 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,06309629 0,06982966 ! neuromuscular process GO:0050905 99 50 0,000 0,06434267 0,0711763 ! regulation of ossification GO:0030278 117 50 0,000 0,06434267 0,07114359 ! inner ear development GO:0048839 79 50 0,000 0,06434267 0,07111092 ! histone modification GO:0016570 91 50 0,000 0,06434267 0,07107827 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,06434267 0,07104565 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,06434267 0,07101306 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,06434267 0,0709805 ! positive regulation of binding GO:0051099 78 51 0,000 0,06558743 0,07232051 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,06558743 0,07228739 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06558743 0,07225429 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06558743 0,07222122 ! excretion GO:0007588 83 51 0,000 0,06558743 0,07218818 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,06558743 0,07215517 ! chromatin remodeling GO:0006338 109 51 0,000 0,06558743 0,07212219 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06558743 0,07208925 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06558743 0,07205633 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06558743 0,07202344 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,06683058 0,0733551 ! covalent chromatin modification GO:0016569 101 52 0,000 0,06683058 0,07332165 ! amino acid activation GO:0043038 92 52 0,000 0,06683058 0,07328823 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,06683058 0,07325484 ! synapse organization GO:0050808 85 52 0,000 0,06683058 0,07322148 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,06807212 0,0745478 ! RNA catabolic process GO:0006401 93 53 0,000 0,06807212 0,07451388 ! regulation of translational initiation GO:0006446 82 53 0,000 0,06807212 0,07448 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,06807212 0,07444614 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,06807212 0,07441232 ! cell maturation GO:0048469 100 53 0,000 0,06807212 0,07437853 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,06931204 0,07569894 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,06931204 0,0756646 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,06931204 0,07563028 ! cell recognition GO:0008037 85 54 0,000 0,06931204 0,075596 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,06931204 0,07556175 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,06931204 0,07552752 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,06931204 0,07549333 ! chloride transport GO:0006821 90 55 0,000 0,07055036 0,07680731 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,07055036 0,07677258 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,07055036 0,07673787 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,07055036 0,07670319 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,07055036 0,07666855 ! aging GO:0007568 103 55 0,000 0,07055036 0,07663393 ! gastrulation GO:0007369 112 55 0,000 0,07055036 0,07659935 ! RNA elongation GO:0006354 79 55 0,000 0,07055036 0,0765648 ! nuclear export GO:0051168 97 55 0,000 0,07055036 0,07653028 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,07055036 0,07649579 ! sensory perception of smell GO:0007608 80 56 0,000 0,07178707 0,07780166 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,07178707 0,07776663 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,07178707 0,07773163 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,07178707 0,07769667 ! regulation of DNA replication GO:0006275 101 56 0,000 0,07178707 0,07766173 ! proton transport GO:0015992 94 56 0,000 0,07178707 0,07762683 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,07302218 0,07892693 ! muscle fiber development GO:0048747 112 57 0,000 0,07302218 0,07889149 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,07302218 0,07885608 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,07302218 0,07882071 ! maintenance of location GO:0051235 118 57 0,000 0,07302218 0,07878536 ! hydrogen transport GO:0006818 97 58 0,000 0,07425568 0,08008031 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,07425568 0,08004443 ! regulation of endocytosis GO:0030100 91 58 0,000 0,07425568 0,08000858 ! adult behavior GO:0030534 99 58 0,000 0,07425568 0,07997277 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,07425568 0,07993699 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07548758 0,0812268 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,07548758 0,08119049 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,07548758 0,08115421 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,07548758 0,08111796 ! DNA catabolic process GO:0006308 86 59 0,000 0,07548758 0,08108175 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,07548758 0,08104557 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,07671789 0,08232972 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,07671789 0,08229302 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,07671789 0,08225634 ! regulation of heart contraction GO:0008016 110 60 0,000 0,07671789 0,0822197 ! camera-type eye development GO:0043010 116 60 0,000 0,07671789 0,0821831 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,07671789 0,08214652 ! kidney development GO:0001822 122 60 0,000 0,07671789 0,08210998 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,07794659 0,08338795 ! mesoderm development GO:0007498 119 61 0,000 0,07794659 0,08335089 ! tRNA processing GO:0008033 89 61 0,000 0,07794659 0,08331386 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,07794659 0,08327687 ! ear development GO:0043583 103 62 0,000 0,07917371 0,08455035 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,07917371 0,08451284 ! gonad development GO:0008406 98 62 0,000 0,07917371 0,08447536 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,07917371 0,08443792 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,08039923 0,08570693 ! detection of external stimulus GO:0009581 91 63 0,000 0,08039923 0,08566898 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,08039923 0,08563105 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,08039923 0,08559316 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,08162316 0,08685773 ! cell redox homeostasis GO:0045454 102 64 0,000 0,08162316 0,08681933 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,08162316 0,08678097 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,08162316 0,08674264 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,08162316 0,08670434 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,08162316 0,08666607 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0828455 0,08792514 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0828455 0,08788637 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0828455 0,08784763 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,08406626 0,08910283 ! actin filament organization GO:0007015 148 66 0,000 0,08406626 0,08906359 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,08406626 0,08902439 ! extracellular matrix organization GO:0030198 133 66 0,000 0,08406626 0,08898523 ! secondary metabolic process GO:0019748 116 66 0,000 0,08406626 0,0889461 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,08528543 0,09019637 ! lung development GO:0030324 144 67 0,000 0,08528543 0,09015675 ! chromosome segregation GO:0007059 113 67 0,000 0,08528543 0,09011715 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,08528543 0,09007759 ! hexose catabolic process GO:0019320 104 67 0,000 0,08528543 0,09003807 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,08528543 0,08999858 ! adaptive immune response GO:0002250 119 67 0,000 0,08528543 0,08995912 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,08528543 0,0899197 ! amino acid transport GO:0006865 125 68 0,000 0,08650302 0,0911635 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,08650302 0,09112359 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,08650302 0,09108371 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,08650302 0,09104386 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,08650302 0,09100406 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,08650302 0,09096428 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,08771903 0,09220271 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,08771903 0,09216244 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,08771903 0,09212221 ! urogenital system development GO:0001655 137 69 0,000 0,08771903 0,09208202 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,08771903 0,09204186 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,08771903 0,09200174 ! antigen processing and presentation GO:0019882 104 69 0,000 0,08771903 0,09196165 ! appendage morphogenesis GO:0035107 135 70 0,000 0,08893346 0,09319421 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,08893346 0,09315364 ! amine catabolic process GO:0009310 117 71 0,000 0,09014632 0,09438296 ! reproductive structure development GO:0048608 113 71 0,000 0,09014632 0,09434191 ! appendage development GO:0048736 136 71 0,000 0,09014632 0,09430089 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,09014632 0,09425991 ! B cell activation GO:0042113 160 71 0,000 0,09014632 0,09421896 ! regulation of immune effector process GO:0002697 137 71 0,000 0,09014632 0,09417805 ! acute inflammatory response GO:0002526 113 72 0,000 0,0913576 0,09540208 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,0913576 0,09536069 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,0913576 0,09531934 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,0913576 0,09527802 ! respiratory system development GO:0060541 153 72 0,000 0,0913576 0,09523674 ! learning or memory GO:0007611 147 73 0,000 0,09256731 0,09645602 ! regulation of blood pressure GO:0008217 125 73 0,000 0,09256731 0,09641426 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,09256731 0,09637254 ! axon guidance GO:0007411 139 73 0,000 0,09256731 0,09633086 ! fertilization GO:0009566 90 73 0,000 0,09256731 0,09628921 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,09377545 0,09750377 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,09377545 0,09746165 ! neurotransmitter transport GO:0006836 123 74 0,000 0,09377545 0,09741957 ! meiosis GO:0007126 121 74 0,000 0,09377545 0,09737753 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,09377545 0,09733552 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,09377545 0,09729354 ! eye development GO:0001654 143 74 0,000 0,09377545 0,09725161 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,09498202 0,09846046 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,09498202 0,09841806 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,09498202 0,09837569 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,09498202 0,09833336 ! meiotic cell cycle GO:0051321 122 75 0,000 0,09498202 0,09829107 ! rhythmic process GO:0048511 128 75 0,000 0,09498202 0,09824881 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,09498202 0,09820659 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,09618702 0,09940978 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,09618702 0,0993671 ! defense response to bacterium GO:0042742 89 76 0,000 0,09618702 0,09932445 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,09618702 0,09928184 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,09618702 0,09923927 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,09739046 0,10043783 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,09739046 0,10039479 ! blood coagulation GO:0007596 146 78 0,000 0,09859234 0,10159022 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,09859234 0,10154673 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,09859234 0,10150328 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,09859234 0,10145986 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,09979265 0,10265119 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,09979265 0,10260732 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,09979265 0,10256349 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,09979265 0,1025197 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,10099141 0,10370693 ! response to metal ion GO:0010038 140 80 0,000 0,10099141 0,10366269 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,10099141 0,10361848 ! inorganic anion transport GO:0015698 138 80 0,000 0,10099141 0,10357431 ! T cell activation GO:0042110 168 81 0,000 0,10218861 0,10475748 ! digestion GO:0007586 112 81 0,000 0,10218861 0,10471286 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,10218861 0,10466829 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,10218861 0,10462375 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,10218861 0,10457924 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,10338426 0,10575788 ! response to drug GO:0042493 143 82 0,000 0,10338426 0,10571293 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,10338426 0,10566803 ! regulation of lyase activity GO:0051339 160 83 0,000 0,10457836 0,10684311 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,1057709 0,10801561 ! hemostasis GO:0007599 158 84 0,000 0,1057709 0,10796979 ! regulation of ligase activity GO:0051340 142 84 0,000 0,1057709 0,107924 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,1057709 0,10787825 ! response to unfolded protein GO:0006986 131 85 0,000 0,10696189 0,10904675 ! nucleosome assembly GO:0006334 122 85 0,000 0,10696189 0,10900056 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,10696189 0,10895441 ! amine biosynthetic process GO:0009309 138 86 0,000 0,10815134 0,1101194 ! response to inorganic substance GO:0010035 153 86 0,000 0,10815134 0,11007281 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,10815134 0,11002627 ! chromatin assembly GO:0031497 124 86 0,000 0,10815134 0,10997977 ! alcohol catabolic process GO:0046164 130 86 0,000 0,10815134 0,1099333 ! amine transport GO:0015837 155 86 0,000 0,10815134 0,10988688 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,10933925 0,11104695 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,10933925 0,1110001 ! cellular respiration GO:0045333 135 88 0,000 0,11052561 0,11215716 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,11052561 0,11210987 ! regulation of DNA binding GO:0051101 155 88 0,000 0,11052561 0,11206263 ! regulation of neurological system process GO:0031644 148 88 0,000 0,11052561 0,11201542 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,11052561 0,11196826 ! cellular defense response GO:0006968 114 89 0,000 0,11171043 0,11312091 ! ossification GO:0001503 188 90 0,000 0,11289371 0,11427104 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,11289371 0,11422299 ! sex differentiation GO:0007548 145 90 0,000 0,11289371 0,11417498 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,11289371 0,114127 ! bone development GO:0060348 189 91 0,000 0,11407546 0,11527322 ! response to protein stimulus GO:0051789 149 91 0,000 0,11407546 0,11522483 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,11407546 0,11517648 ! regulation of defense response GO:0031347 149 92 0,000 0,11525567 0,11631927 ! nucleosome organization GO:0034728 138 92 0,000 0,11525567 0,1162705 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,11525567 0,11622177 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,11643434 0,11736113 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,11643434 0,11731199 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,11761149 0,11844841 ! female pregnancy GO:0007565 164 94 0,000 0,11761149 0,11839885 ! transcription initiation GO:0006352 153 94 0,000 0,11761149 0,11834933 ! regulation of T cell activation GO:0050863 158 94 0,000 0,11761149 0,11829985 ! forebrain development GO:0030900 188 95 0,000 0,11878711 0,11943242 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,11878711 0,11938253 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,11996119 0,12051216 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,11996119 0,12046187 ! positive regulation of immune response GO:0050778 156 96 0,000 0,11996119 0,12041161 ! detection of stimulus GO:0051606 151 96 0,000 0,11996119 0,1203614 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,12113376 0,12148721 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,12113376 0,12143659 ! hormone metabolic process GO:0042445 157 97 0,000 0,12113376 0,12138602 ! response to virus GO:0009615 160 98 0,000 0,1223048 0,12250847 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1223048 0,12245749 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,1223048 0,12240655 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,12347432 0,12352566 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,12347432 0,12347432