pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/798-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin receptor signaling pathway GO:0008286 64 26 3,000 5,785E-08 1,392E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,621E-07 1,95E-04 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 2,526E-07 2,026E-04 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 3,466E-07 2,085E-04 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 5,65E-07 2,719E-04 ! response to insulin stimulus GO:0032868 95 46 3,000 6,181E-07 2,479E-04 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 1,019E-06 3,502E-04 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 1,946E-06 5,851E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,95E-06 5,214E-04 ! patterning of blood vessels GO:0001569 39 18 2,000 2,338E-06 5,625E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,259E-06 7,129E-04 ! collagen catabolic process GO:0030574 28 21 2,000 3,799E-06 7,617E-04 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 6,377E-06 1,18E-03 ! tube morphogenesis GO:0035239 176 86 3,000 7,709E-06 1,325E-03 ! multicellular organismal catabolic process GO:0044243 36 27 2,000 8,303E-06 1,332E-03 ! collagen metabolic process GO:0032963 45 31 2,000 1,271E-05 1,911E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 2,000 1,687E-05 2,387E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,08E-05 2,781E-03 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 2,768E-05 3,505E-03 ! protein refolding GO:0042026 15 6 1,000 3,117E-05 3,75E-03 ! male sex determination GO:0030238 15 6 1,000 3,117E-05 3,572E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,227E-05 4,622E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 4,36E-05 4,561E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of respiratory burst GO:0060263 11 7 1,000 4,36E-05 4,371E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 5,808E-05 5,59E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 5,808E-05 5,375E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,808E-05 5,176E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 7,461E-05 6,411E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 7,461E-05 6,19E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 7,461E-05 5,984E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 21 9 1,000 7,461E-05 5,791E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 7,461E-05 5,61E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 7,461E-05 5,44E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 9,317E-05 6,593E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 9,317E-05 6,405E-03 GO:0043470|regulation of carbohydrate catabolic process, ! natural killer cell mediated immunity GO:0002228 18 10 1,000 9,317E-05 6,227E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of embryonic development GO:0045995 27 11 1,000 1,138E-04 7,398E-03 ! activation of MAPK activity GO:0000187 115 67 2,000 1,306E-04 8,266E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,364E-04 8,415E-03 ! virus-host interaction GO:0019048 29 12 1,000 1,364E-04 8,205E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,364E-04 8,004E-03 ! leukocyte mediated cytotoxicity GO:0001909 26 12 1,000 1,364E-04 7,814E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,611E-04 9,011E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! bone mineralization GO:0030282 17 14 1,000 1,877E-04 0,01026482 ! protein oligomerization GO:0051259 139 78 2,000 2,05E-04 0,01096186 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 2,164E-04 0,01131854 ! cell killing GO:0001906 29 15 1,000 2,164E-04 0,01107772 ! response to hypoxia GO:0001666 171 81 2,000 2,292E-04 0,01149032 ! response to oxygen levels GO:0070482 176 83 2,000 2,464E-04 0,01209672 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,471E-04 0,01188958 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 2,471E-04 0,01165645 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,471E-04 0,01143229 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,471E-04 0,01121659 ! biomineral formation GO:0031214 20 16 1,000 2,471E-04 0,01100887 ! regulation of protein transport GO:0051223 154 87 2,000 2,83E-04 0,01238203 GO:0070201|regulation of establishment of protein localization, ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,144E-04 0,01350989 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 3,144E-04 0,01327288 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 3,444E-04 0,01428729 ! lipid phosphorylation GO:0046834 35 19 1,000 3,511E-04 0,01431823 ! female pregnancy GO:0007565 164 94 2,000 3,554E-04 0,01425184 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 3,666E-04 0,0144606 ! regulation of protein localization GO:0032880 176 97 2,000 3,897E-04 0,01512421 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,898E-04 0,0148852 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 3,898E-04 0,01465262 GO:0010675|regulation of cellular carbohydrate metabolic process, ! hindlimb morphogenesis GO:0035137 43 21 1,000 4,304E-04 0,01593105 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 4,73E-04 0,01724262 ! positive regulation of DNA replication GO:0045740 43 23 1,000 5,176E-04 0,01858565 ! sex determination GO:0007530 47 23 1,000 5,176E-04 0,01831233 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 5,641E-04 0,01966929 ! protein tetramerization GO:0051262 52 24 1,000 5,641E-04 0,0193883 ! interaction with host GO:0051701 62 25 1,000 6,126E-04 0,02075814 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 6,63E-04 0,02215508 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 6,63E-04 0,02185158 ! positive regulation of nuclear division GO:0051785 40 26 1,000 6,63E-04 0,02155629 GO:0045840|positive regulation of mitosis, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 7,154E-04 0,02294908 ! mitochondrial membrane organization GO:0007006 57 27 1,000 7,154E-04 0,02264711 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 7,697E-04 0,02405013 ! response to mechanical stimulus GO:0009612 57 32 1,000 1,006E-03 0,03103784 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,006E-03 0,03064496 ! positive regulation of catabolic process GO:0009896 64 32 1,000 1,006E-03 0,0302619 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 1,136E-03 0,03374245 ! negative regulation of secretion GO:0051048 63 35 1,000 1,204E-03 0,03531824 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 1,418E-03 0,04111166 ! carbohydrate homeostasis GO:0033500 53 38 1,000 1,418E-03 0,04062224 GO:0042593|glucose homeostasis, ! regulation of intracellular protein transport GO:0033157 80 42 1,000 1,731E-03 0,04898484 ! regulation of protein secretion GO:0050708 71 42 1,000 1,731E-03 0,04841525 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 2,073E-03 0,05731771 ! positive regulation of protein transport GO:0051222 72 46 1,000 2,073E-03 0,05666637 ! regulation of JNK cascade GO:0046328 94 47 1,000 2,163E-03 0,05846569 ! protein homooligomerization GO:0051260 76 47 1,000 2,163E-03 0,05781607 ! positive regulation of cell cycle GO:0045787 89 48 1,000 2,255E-03 0,0596116 ! mitochondrial transport GO:0006839 82 48 1,000 2,255E-03 0,05896365 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 2,255E-03 0,05832963 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 2,444E-03 0,06255569 ! response to estrogen stimulus GO:0043627 93 51 1,000 2,541E-03 0,06436399 ! positive regulation of growth GO:0045927 90 52 1,000 2,641E-03 0,06617996 ! cartilage development GO:0051216 90 52 1,000 2,641E-03 0,06549769 ! heart morphogenesis GO:0003007 97 55 1,000 2,949E-03 0,07240163 ! regulation of DNA replication GO:0006275 101 56 1,000 3,055E-03 0,07425599 ! positive regulation of organelle organization GO:0010638 100 56 1,000 3,055E-03 0,07351343 ! positive regulation of cell migration GO:0030335 126 57 1,000 3,164E-03 0,07536254 ! lipid modification GO:0030258 97 57 1,000 3,164E-03 0,07462369 ! regulation of intracellular transport GO:0032386 101 57 1,000 3,164E-03 0,07389919 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 3,499E-03 0,08094281 ! viral reproductive process GO:0022415 126 62 1,000 3,731E-03 0,08549426 ! regulation of mitosis GO:0007088 105 63 1,000 3,85E-03 0,08738349 GO:0051783|regulation of nuclear division, ! lymphocyte mediated immunity GO:0002449 114 64 1,000 3,97E-03 0,08927669 ! positive regulation of cell motion GO:0051272 146 64 1,000 3,97E-03 0,08845005 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 4,093E-03 0,09033717 GO:0035113|embryonic appendage morphogenesis, ! developmental maturation GO:0021700 116 66 1,000 4,217E-03 0,09222797 ! regulation of cellular response to stress GO:0080135 128 67 1,000 4,342E-03 0,09412223 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 4,342E-03 0,09328185 ! viral reproduction GO:0016032 134 68 1,000 4,47E-03 0,09517002 ! appendage morphogenesis GO:0035107 135 70 1,000 4,73E-03 0,09982382 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 4,862E-03 0,10172999 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 4,862E-03 0,10085301 ! regulation of caspase activity GO:0043281 122 72 1,000 4,997E-03 0,10275289 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 4,997E-03 0,1018821 ! leukocyte mediated immunity GO:0002443 128 74 1,000 5,27E-03 0,10655995 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 5,27E-03 0,10567195 ! cell-matrix adhesion GO:0007160 163 75 1,000 5,41E-03 0,10757038 ! regulation of catabolic process GO:0009894 161 76 1,000 5,551E-03 0,10947095 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 5,838E-03 0,11419884 ! activation of protein kinase activity GO:0032147 147 79 1,000 5,984E-03 0,11611286 ! regulation of peptidase activity GO:0052547 134 79 1,000 5,984E-03 0,11518396 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 5,984E-03 0,1142698 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 6,281E-03 0,11900069 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 6,281E-03 0,11807099 ! negative regulation of transport GO:0051051 153 84 1,000 6,74E-03 0,12570221 ! response to unfolded protein GO:0006986 131 85 1,000 6,896E-03 0,12762307 ! mitochondrion organization GO:0007005 148 86 1,000 7,053E-03 0,12954467 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 7,284E-03 0,1327677 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,284E-03 0,13176945 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,284E-03 0,1307861 ! positive regulation of helicase activity GO:0051096 11 5 0,000 7,284E-03 0,12981731 ! neuron fate determination GO:0048664 7 5 0,000 7,284E-03 0,12886277 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,284E-03 0,12792217 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 7,284E-03 0,12699519 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,284E-03 0,12608156 ! polyol transport GO:0015791 12 5 0,000 7,284E-03 0,12518098 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 7,284E-03 0,12429317 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,284E-03 0,12341786 ! response to superoxide GO:0000303 10 5 0,000 7,284E-03 0,1225548 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,284E-03 0,12170373 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 7,284E-03 0,12086439 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 7,284E-03 0,12003655 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,284E-03 0,11921998 ! female meiosis GO:0007143 7 5 0,000 7,284E-03 0,11841444 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,284E-03 0,11761971 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,284E-03 0,11683558 ! cobalt ion transport GO:0006824 11 5 0,000 7,284E-03 0,11606183 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 7,284E-03 0,11529827 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 7,284E-03 0,11454468 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 7,284E-03 0,11380089 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,284E-03 0,11306669 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,284E-03 0,1123419 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 7,284E-03 0,11162635 ! embryonic camera-type eye development GO:0031076 10 5 0,000 7,284E-03 0,11091985 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,284E-03 0,11022224 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 7,284E-03 0,10953335 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 7,284E-03 0,10885302 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,284E-03 0,10818109 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,284E-03 0,1075174 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,284E-03 0,10686181 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 7,284E-03 0,10621416 ! negative chemotaxis GO:0050919 14 5 0,000 7,284E-03 0,10557432 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,284E-03 0,10494214 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,284E-03 0,10431748 ! sensory perception of bitter taste GO:0050913 7 5 0,000 7,284E-03 0,10370022 ! behavioral response to pain GO:0048266 9 5 0,000 7,284E-03 0,10309022 ! clathrin coat assembly GO:0048268 14 5 0,000 7,284E-03 0,10248735 ! Notch receptor processing GO:0007220 8 5 0,000 7,284E-03 0,10189149 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,284E-03 0,10130252 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,284E-03 0,10072033 ! micturition GO:0060073 9 5 0,000 7,284E-03 0,10014478 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,284E-03 0,09957578 ! copulation GO:0007620 9 5 0,000 7,284E-03 0,0990132 ! glial cell fate commitment GO:0021781 13 5 0,000 7,284E-03 0,09845695 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,284E-03 0,09790691 ! spermidine metabolic process GO:0008216 7 5 0,000 7,284E-03 0,09736298 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,284E-03 0,09682506 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,284E-03 0,09629306 ! apoptotic cell clearance GO:0043277 20 5 0,000 7,284E-03 0,09576687 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,284E-03 0,0952464 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,284E-03 0,09473155 ! grooming behavior GO:0007625 6 5 0,000 7,284E-03 0,09422224 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,284E-03 0,09371838 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 7,284E-03 0,09321988 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,284E-03 0,09272665 ! response to protozoan GO:0001562 10 5 0,000 7,284E-03 0,09223861 ! lymph vessel development GO:0001945 10 5 0,000 7,284E-03 0,09175569 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 7,284E-03 0,0912778 ! endochondral ossification GO:0001958 16 5 0,000 7,284E-03 0,09080485 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,284E-03 0,09033679 ! parathyroid gland development GO:0060017 13 5 0,000 7,284E-03 0,08987352 ! anagen GO:0042640 6 5 0,000 7,284E-03 0,08941498 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,284E-03 0,0889611 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,284E-03 0,0885118 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 7,284E-03 0,08806702 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 7,284E-03 0,08762668 ! dorsal spinal cord development GO:0021516 7 5 0,000 7,284E-03 0,08719073 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 7,284E-03 0,08675909 ! sphingoid catabolic process GO:0046521 6 5 0,000 7,284E-03 0,08633171 ! skeletal myofibril assembly GO:0014866 10 5 0,000 7,284E-03 0,08590851 ! smooth muscle tissue development GO:0048745 28 5 0,000 7,284E-03 0,08548945 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,284E-03 0,08507445 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,284E-03 0,08466346 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,284E-03 0,08425643 ! cardiac muscle fiber development GO:0048739 10 5 0,000 7,284E-03 0,08385329 ! transepithelial chloride transport GO:0030321 9 5 0,000 7,284E-03 0,08345398 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,284E-03 0,08305847 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 7,284E-03 0,08266668 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 7,284E-03 0,08227858 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,284E-03 0,0818941 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,284E-03 0,08151319 ! histidine catabolic process GO:0006548 6 5 0,000 7,284E-03 0,08113582 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 7,284E-03 0,08076192 ! microvillus organization GO:0032528 7 5 0,000 7,284E-03 0,08039145 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 7,284E-03 0,08002437 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,284E-03 0,07966062 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,284E-03 0,07930017 ! tryptophan metabolic process GO:0006568 9 5 0,000 7,284E-03 0,07894296 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 7,284E-03 0,07858895 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,284E-03 0,07823811 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 7,284E-03 0,07789039 ! polyol catabolic process GO:0046174 7 5 0,000 7,284E-03 0,07754574 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,284E-03 0,07720413 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,284E-03 0,07686551 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,284E-03 0,07652985 ! muscle cell migration GO:0014812 8 5 0,000 7,284E-03 0,07619712 ! mitochondrial fission GO:0000266 8 5 0,000 7,284E-03 0,07586726 ! sister chromatid cohesion GO:0007062 12 5 0,000 7,284E-03 0,07554024 ! mRNA transcription GO:0009299 9 5 0,000 7,284E-03 0,07521604 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 7,284E-03 0,0748946 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 7,284E-03 0,0745759 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 7,284E-03 0,0742599 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,284E-03 0,07394657 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,284E-03 0,07363587 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,284E-03 0,07332777 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,284E-03 0,07302224 ! response to food GO:0032094 6 5 0,000 7,284E-03 0,07271924 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,284E-03 0,07241875 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,284E-03 0,07212073 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 7,284E-03 0,07182515 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,284E-03 0,07153199 ! paraxial mesoderm development GO:0048339 14 5 0,000 7,284E-03 0,07124121 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 7,284E-03 0,07095278 ! forebrain neuron development GO:0021884 13 5 0,000 7,284E-03 0,07066668 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,284E-03 0,07038288 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 7,284E-03 0,07010135 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,284E-03 0,06982206 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,284E-03 0,06954499 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,284E-03 0,06927011 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 7,284E-03 0,06899739 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,284E-03 0,06872681 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 7,284E-03 0,06845835 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 7,284E-03 0,06819197 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,284E-03 0,06792766 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 7,284E-03 0,06766539 ! basic amino acid transport GO:0015802 11 5 0,000 7,284E-03 0,06740514 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,284E-03 0,06714688 ! early endosome to late endosome transport GO:0045022 12 5 0,000 7,284E-03 0,0668906 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,284E-03 0,06663626 ! depyrimidination GO:0045008 10 5 0,000 7,284E-03 0,06638385 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,284E-03 0,06613335 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,284E-03 0,06588472 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,284E-03 0,06563797 ! zinc ion homeostasis GO:0055069 8 5 0,000 7,284E-03 0,06539305 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 7,284E-03 0,06514995 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 7,284E-03 0,06490865 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,284E-03 0,06466914 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,284E-03 0,06443139 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,284E-03 0,06419537 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 7,284E-03 0,06396108 ! peptidyl-arginine modification GO:0018195 9 5 0,000 7,284E-03 0,0637285 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,284E-03 0,0634976 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,284E-03 0,06326836 ! response to arsenic GO:0046685 10 5 0,000 7,284E-03 0,06304078 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,284E-03 0,06281483 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,284E-03 0,06259049 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 7,284E-03 0,06236775 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 7,284E-03 0,06214658 ! response to cadmium ion GO:0046686 7 5 0,000 7,284E-03 0,06192699 ! bile acid biosynthetic process GO:0006699 6 5 0,000 7,284E-03 0,06170893 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 7,284E-03 0,06149241 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,284E-03 0,0612774 ! decidualization GO:0046697 11 5 0,000 7,284E-03 0,06106389 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 7,284E-03 0,06085186 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 7,284E-03 0,0606413 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,284E-03 0,0604322 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,284E-03 0,06022452 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 7,284E-03 0,06001828 ! base conversion or substitution editing GO:0016553 5 5 0,000 7,284E-03 0,05981344 ! neural tube patterning GO:0021532 7 5 0,000 7,284E-03 0,05960999 ! embryonic cleavage GO:0040016 6 5 0,000 7,284E-03 0,05940792 ! peroxisome fission GO:0016559 5 5 0,000 7,284E-03 0,05920722 ! histone demethylation GO:0016577 10 5 0,000 7,284E-03 0,05900787 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 7,284E-03 0,05880985 ! mitotic recombination GO:0006312 9 5 0,000 7,284E-03 0,05861317 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,284E-03 0,05841779 ! metaphase plate congression GO:0051310 7 5 0,000 7,284E-03 0,05822371 ! regulation of sterol transport GO:0032371 7 5 0,000 7,284E-03 0,05803092 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,284E-03 0,0578394 ! enteric nervous system development GO:0048484 8 5 0,000 7,284E-03 0,05764913 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 7,284E-03 0,05746012 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 7,284E-03 0,05727234 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 7,284E-03 0,05708579 ! muscle cell proliferation GO:0033002 11 5 0,000 7,284E-03 0,05690044 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,284E-03 0,0567163 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 7,284E-03 0,05653334 ! plasminogen activation GO:0031639 5 5 0,000 7,284E-03 0,05635157 ! B cell homeostasis GO:0001782 13 5 0,000 7,284E-03 0,05617095 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,284E-03 0,05599149 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,284E-03 0,05581317 ! metaphase GO:0051323 8 5 0,000 7,284E-03 0,05563599 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 7,284E-03 0,05545993 ! cellular response to nutrient GO:0031670 8 5 0,000 7,284E-03 0,05528497 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,284E-03 0,05511112 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,284E-03 0,05493836 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,284E-03 0,05476668 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 7,284E-03 0,05459606 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 7,284E-03 0,05442651 ! response to redox state GO:0051775 5 5 0,000 7,284E-03 0,05425801 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 7,284E-03 0,05409055 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 7,284E-03 0,05392411 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,284E-03 0,0537587 ! regulation of telomerase activity GO:0051972 6 5 0,000 7,284E-03 0,0535943 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,284E-03 0,0534309 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 7,284E-03 0,0532685 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,284E-03 0,05310708 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 7,284E-03 0,05294664 ! striatum development GO:0021756 9 5 0,000 7,284E-03 0,05278716 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 7,284E-03 0,05262864 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 7,284E-03 0,05247107 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,284E-03 0,05231444 ! glial cell migration GO:0008347 11 5 0,000 7,284E-03 0,05215874 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,284E-03 0,05200397 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 7,284E-03 0,05185011 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,284E-03 0,05169716 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,284E-03 0,05154511 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,284E-03 0,05139395 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,284E-03 0,05124367 ! neuroprotection GO:0043526 6 5 0,000 7,284E-03 0,05109428 ! neural plate development GO:0001840 8 5 0,000 7,284E-03 0,05094575 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,284E-03 0,05079808 ! regulation of sensory perception GO:0051931 7 5 0,000 7,284E-03 0,05065126 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,284E-03 0,05050529 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,284E-03 0,05036016 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 7,284E-03 0,05021586 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 7,284E-03 0,05007239 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,284E-03 0,04992973 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,284E-03 0,04978789 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,284E-03 0,04964685 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,284E-03 0,0495066 ! spindle assembly GO:0051225 6 5 0,000 7,284E-03 0,04936715 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 7,284E-03 0,04922847 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,284E-03 0,04909058 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,284E-03 0,04895345 ! drug metabolic process GO:0017144 6 5 0,000 7,284E-03 0,04881709 ! stem cell division GO:0017145 11 5 0,000 7,284E-03 0,04868149 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,284E-03 0,04854664 ! organ regeneration GO:0031100 7 5 0,000 7,284E-03 0,04841253 ! carnitine metabolic process GO:0009437 7 5 0,000 7,284E-03 0,04827916 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 7,284E-03 0,04814653 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,284E-03 0,04801462 ! ossification GO:0001503 188 90 1,000 7,7E-03 0,05061996 ! regulation of cell cycle process GO:0010564 149 90 1,000 7,7E-03 0,05048203 ! bone development GO:0060348 189 91 1,000 7,866E-03 0,05142873 ! response to protein stimulus GO:0051789 149 91 1,000 7,866E-03 0,05128935 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,735E-03 0,05679839 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,735E-03 0,05664529 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 8,735E-03 0,05649302 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 8,735E-03 0,05634156 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,735E-03 0,05619092 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 8,735E-03 0,05604108 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 8,735E-03 0,05589203 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,735E-03 0,05574378 ! sleep GO:0030431 13 6 0,000 8,735E-03 0,05559631 ! response to oxygen radical GO:0000305 11 6 0,000 8,735E-03 0,05544961 ! positive regulation of axon extension GO:0045773 11 6 0,000 8,735E-03 0,05530369 ! myoblast cell fate commitment GO:0048625 16 6 0,000 8,735E-03 0,05515854 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 8,735E-03 0,05501414 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 8,735E-03 0,0548705 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,735E-03 0,05472761 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,735E-03 0,05458546 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 8,735E-03 0,05444405 ! forebrain regionalization GO:0021871 8 6 0,000 8,735E-03 0,05430337 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,735E-03 0,05416341 ! male meiosis GO:0007140 7 6 0,000 8,735E-03 0,05402417 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,735E-03 0,05388565 ! response to zinc ion GO:0010043 9 6 0,000 8,735E-03 0,05374783 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,735E-03 0,05361072 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 8,735E-03 0,05347431 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 8,735E-03 0,05333859 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,735E-03 0,05320355 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,735E-03 0,0530692 ! malate metabolic process GO:0006108 11 6 0,000 8,735E-03 0,05293552 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 8,735E-03 0,05280252 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 8,735E-03 0,05267018 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,735E-03 0,05253851 ! opsonization GO:0008228 8 6 0,000 8,735E-03 0,05240749 ! mating behavior GO:0007617 7 6 0,000 8,735E-03 0,05227712 ! neuron remodeling GO:0016322 15 6 0,000 8,735E-03 0,0521474 ! erythrocyte maturation GO:0043249 7 6 0,000 8,735E-03 0,05201833 ! embryonic hemopoiesis GO:0035162 14 6 0,000 8,735E-03 0,05188988 ! equilibrioception GO:0050957 14 6 0,000 8,735E-03 0,05176208 ! protein amino acid dealkylation GO:0008214 12 6 0,000 8,735E-03 0,0516349 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 8,735E-03 0,05150834 ! photoreceptor cell development GO:0042461 10 6 0,000 8,735E-03 0,0513824 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 8,735E-03 0,05125708 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,735E-03 0,05113237 ! response to interferon-gamma GO:0034341 15 6 0,000 8,735E-03 0,05100826 ! toxin metabolic process GO:0009404 11 6 0,000 8,735E-03 0,05088475 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,735E-03 0,05076184 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 8,735E-03 0,05063953 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 8,735E-03 0,0505178 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 8,735E-03 0,05039665 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 8,735E-03 0,05027608 ! cGMP-mediated signaling GO:0019934 13 6 0,000 8,735E-03 0,05015609 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,735E-03 0,05003667 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 8,735E-03 0,04991782 ! thymic T cell selection GO:0045061 12 6 0,000 8,735E-03 0,04979953 ! protein lipoylation GO:0009249 10 6 0,000 8,735E-03 0,0496818 ! cysteine metabolic process GO:0006534 10 6 0,000 8,735E-03 0,04956463 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,735E-03 0,04944801 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 8,735E-03 0,04933193 ! glutamate catabolic process GO:0006538 10 6 0,000 8,735E-03 0,0492164 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 8,735E-03 0,04910141 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 8,735E-03 0,04898695 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 8,735E-03 0,04887303 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 8,735E-03 0,04875964 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,735E-03 0,04864677 ! hyperosmotic response GO:0006972 9 6 0,000 8,735E-03 0,04853442 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 8,735E-03 0,04842259 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 8,735E-03 0,04831127 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,735E-03 0,04820047 ! urea metabolic process GO:0019627 7 6 0,000 8,735E-03 0,04809017 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,735E-03 0,04798037 ! neutrophil activation GO:0042119 8 6 0,000 8,735E-03 0,04787108 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,735E-03 0,04776228 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 8,735E-03 0,04765398 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,735E-03 0,04754616 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 8,735E-03 0,04743883 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,735E-03 0,04733199 ! neuron apoptosis GO:0051402 9 6 0,000 8,735E-03 0,04722563 ! nucleoside salvage GO:0043174 9 6 0,000 8,735E-03 0,04711974 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 8,735E-03 0,04701433 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,735E-03 0,04690938 ! T cell mediated immunity GO:0002456 16 6 0,000 8,735E-03 0,04680491 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,735E-03 0,0467009 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 8,735E-03 0,04659735 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 8,735E-03 0,04649426 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,735E-03 0,04639162 ! positive regulation of exocytosis GO:0045921 8 6 0,000 8,735E-03 0,04628943 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 8,735E-03 0,0461877 ! 5S class rRNA transcription GO:0042791 11 6 0,000 8,735E-03 0,04608641 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,735E-03 0,04598557 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 8,735E-03 0,04588516 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 8,735E-03 0,04578519 ! sodium ion homeostasis GO:0055078 11 6 0,000 8,735E-03 0,04568566 ! establishment of spindle localization GO:0051293 12 6 0,000 8,735E-03 0,04558656 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 8,735E-03 0,04548789 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,735E-03 0,04538964 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 8,735E-03 0,04529182 ! neural nucleus development GO:0048857 14 6 0,000 8,735E-03 0,04519442 ! response to UV-C GO:0010225 11 6 0,000 8,735E-03 0,04509743 ! astrocyte development GO:0014002 15 6 0,000 8,735E-03 0,04500086 ! protein targeting to lysosome GO:0006622 10 6 0,000 8,735E-03 0,04490471 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,735E-03 0,04480896 ! interaction with symbiont GO:0051702 13 6 0,000 8,735E-03 0,04471362 ! regulation of dendrite development GO:0050773 16 6 0,000 8,735E-03 0,04461869 ! skeletal muscle contraction GO:0003009 6 6 0,000 8,735E-03 0,04452416 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 8,735E-03 0,04443003 ! response to copper ion GO:0046688 10 6 0,000 8,735E-03 0,04433629 ! response to exogenous dsRNA GO:0043330 10 6 0,000 8,735E-03 0,04424295 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 8,735E-03 0,04415001 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,735E-03 0,04405745 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 8,735E-03 0,04396528 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,735E-03 0,04387349 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 8,735E-03 0,04378209 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,735E-03 0,04369107 ! nucleoside catabolic process GO:0009164 7 6 0,000 8,735E-03 0,04360042 ! hair follicle maturation GO:0048820 7 6 0,000 8,735E-03 0,04351015 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,735E-03 0,04342025 ! Schwann cell development GO:0014044 15 6 0,000 8,735E-03 0,04333073 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 8,735E-03 0,04324157 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 8,735E-03 0,04315278 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 8,735E-03 0,04306435 ! subpallium development GO:0021544 10 6 0,000 8,735E-03 0,04297628 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 8,735E-03 0,04288858 ! histone ubiquitination GO:0016574 8 6 0,000 8,735E-03 0,04280123 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 8,735E-03 0,04271423 ! maintenance of organ identity GO:0048496 9 6 0,000 8,735E-03 0,04262759 ! G2 phase GO:0051319 16 6 0,000 8,735E-03 0,0425413 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 8,735E-03 0,04245536 ! establishment of planar polarity GO:0001736 7 6 0,000 8,735E-03 0,04236976 ! regulation of mast cell activation GO:0033003 12 6 0,000 8,735E-03 0,04228451 ! membrane to membrane docking GO:0022614 14 6 0,000 8,735E-03 0,04219961 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,735E-03 0,04211504 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 8,735E-03 0,04203081 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,735E-03 0,04194691 ! receptor internalization GO:0031623 10 6 0,000 8,735E-03 0,04186335 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 8,735E-03 0,04178013 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 8,735E-03 0,04169723 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,735E-03 0,04161466 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 8,735E-03 0,04153242 ! protein deubiquitination GO:0016579 14 6 0,000 8,735E-03 0,0414505 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 8,735E-03 0,0413689 ! protein destabilization GO:0031648 9 6 0,000 8,735E-03 0,04128763 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 8,735E-03 0,04120667 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 8,735E-03 0,04112603 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 8,735E-03 0,04104571 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 8,735E-03 0,0409657 ! progesterone metabolic process GO:0042448 10 6 0,000 8,735E-03 0,040886 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 8,735E-03 0,04080661 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 8,735E-03 0,04072753 ! negative regulation of axon extension GO:0030517 21 6 0,000 8,735E-03 0,04064875 ! removal of superoxide radicals GO:0019430 11 6 0,000 8,735E-03 0,04057028 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,735E-03 0,04049211 ! determination of adult lifespan GO:0008340 15 6 0,000 8,735E-03 0,04041424 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 8,735E-03 0,04033667 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 8,735E-03 0,04025939 ! cerebellar cortex formation GO:0021697 8 6 0,000 8,735E-03 0,04018242 ! catecholamine transport GO:0051937 9 6 0,000 8,735E-03 0,04010573 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 8,735E-03 0,04002934 ! sensory cilium assembly GO:0035058 10 6 0,000 8,735E-03 0,03995324 ! organ or tissue specific immune response GO:0002251 7 6 0,000 8,735E-03 0,03987743 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 8,735E-03 0,0398019 ! maternal placenta development GO:0001893 12 6 0,000 8,735E-03 0,03972666 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 8,735E-03 0,0396517 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,735E-03 0,03957703 ! negative regulation of B cell activation GO:0050869 13 6 0,000 8,735E-03 0,03950264 ! protein amino acid prenylation GO:0018346 16 6 0,000 8,735E-03 0,03942852 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 8,735E-03 0,03935469 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 8,735E-03 0,03928113 ! positive regulation of coagulation GO:0050820 12 6 0,000 8,735E-03 0,03920784 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 8,894E-03 0,03985062 ! tRNA transcription GO:0009304 14 7 0,000 0,01018308 0,04553994 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01018308 0,04545545 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01018308 0,04537127 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01018308 0,0452874 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01018308 0,04520385 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01018308 0,0451206 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01018308 0,04503766 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01018308 0,04495502 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01018308 0,04487268 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01018308 0,04479065 ! prostate gland development GO:0030850 13 7 0,000 0,01018308 0,04470892 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01018308 0,04462748 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01018308 0,04454634 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01018308 0,04446549 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01018308 0,04438494 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01018308 0,04430468 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01018308 0,0442247 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01018308 0,04414502 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01018308 0,04406562 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01018308 0,04398651 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01018308 0,04390768 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01018308 0,04382913 ! glycolipid transport GO:0046836 10 7 0,000 0,01018308 0,04375087 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01018308 0,04367288 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01018308 0,04359517 ! neuron adhesion GO:0007158 12 7 0,000 0,01018308 0,04351774 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01018308 0,04344058 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01018308 0,04336369 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01018308 0,04328708 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01018308 0,04321073 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01018308 0,04313466 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01018308 0,04305885 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01018308 0,04298331 ! mRNA stabilization GO:0048255 18 7 0,000 0,01018308 0,04290803 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01018308 0,04283302 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01018308 0,04275827 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01018308 0,04268377 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01018308 0,04260954 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01018308 0,04253557 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01018308 0,04246185 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01018308 0,04238838 ! lipoprotein transport GO:0042953 14 7 0,000 0,01018308 0,04231517 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01018308 0,04224222 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01018308 0,04216951 ! rhythmic behavior GO:0007622 15 7 0,000 0,01018308 0,04209705 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01018308 0,04202485 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01018308 0,04195289 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01018308 0,04188117 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01018308 0,0418097 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01018308 0,04173848 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01018308 0,04166749 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01018308 0,04159675 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01018308 0,04152625 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01018308 0,04145598 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01018308 0,04138596 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01018308 0,04131617 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01018308 0,04124661 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01018308 0,04117729 ! spinal cord patterning GO:0021511 13 7 0,000 0,01018308 0,0411082 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01018308 0,04103934 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01018308 0,04097071 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01018308 0,04090231 ! adrenal gland development GO:0030325 17 7 0,000 0,01018308 0,04083414 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01018308 0,0407662 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01018308 0,04069848 ! ovulation GO:0030728 9 7 0,000 0,01018308 0,04063099 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01018308 0,04056372 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01018308 0,04049667 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01018308 0,04042984 ! microtubule nucleation GO:0007020 20 7 0,000 0,01018308 0,04036324 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01018308 0,04029685 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01018308 0,04023068 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01018308 0,04016473 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01018308 0,040099 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01018308 0,04003347 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01018308 0,03996817 ! galactose metabolic process GO:0006012 13 7 0,000 0,01018308 0,03990307 ! vesicle fusion GO:0006906 17 7 0,000 0,01018308 0,03983819 ! response to dietary excess GO:0002021 8 7 0,000 0,01018308 0,03977352 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01018308 0,03970905 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01018308 0,0396448 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01018308 0,03958075 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01018308 0,03951691 ! organ growth GO:0035265 15 7 0,000 0,01018308 0,03945328 ! purine salvage GO:0043101 10 7 0,000 0,01018308 0,03938985 ! nucleoside transport GO:0015858 8 7 0,000 0,01018308 0,03932662 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01018308 0,0392636 ! parturition GO:0007567 14 7 0,000 0,01018308 0,03920078 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01018308 0,03913816 ! rRNA modification GO:0000154 14 7 0,000 0,01018308 0,03907574 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01018308 0,03901351 ! spindle checkpoint GO:0031577 15 7 0,000 0,01018308 0,03895149 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01018308 0,03888966 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01018308 0,03882803 ! macrophage differentiation GO:0030225 11 7 0,000 0,01018308 0,03876659 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01018308 0,03870535 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01018308 0,0386443 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01018308 0,03858344 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01018308 0,03852278 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01018308 0,0384623 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01018308 0,03840202 ! fibrinolysis GO:0042730 10 7 0,000 0,01018308 0,03834192 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01018308 0,03828201 ! eating behavior GO:0042755 7 7 0,000 0,01018308 0,03822229 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01018308 0,03816275 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01018308 0,0381034 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01018308 0,03804423 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01018308 0,03798525 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01018308 0,03792645 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01018308 0,03786783 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01018308 0,03780939 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01018308 0,03775113 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01018308 0,03769306 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01018308 0,03763516 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01018308 0,03757743 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01018308 0,03751989 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01018308 0,03746252 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01018308 0,03740532 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01018308 0,0373483 ! regulation of meiosis GO:0040020 12 7 0,000 0,01018308 0,03729146 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01018308 0,03723478 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01018308 0,03717828 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01018308 0,03712195 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01018308 0,03706579 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01018308 0,0370098 ! transcription termination GO:0006353 13 7 0,000 0,01018308 0,03695398 ! response to tumor cell GO:0002347 13 7 0,000 0,01018308 0,03689832 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01018308 0,03684284 ! anaphase GO:0051322 17 7 0,000 0,01018308 0,03678752 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01018308 0,03673236 ! axonal fasciculation GO:0007413 18 7 0,000 0,01018308 0,03667737 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01018308 0,03662255 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01018308 0,03656789 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01018308 0,03651339 ! diuresis GO:0030146 12 7 0,000 0,01018308 0,03645906 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01018308 0,03640488 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01018308 0,03635087 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01018308 0,03629702 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01018308 0,03624332 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01018308 0,03618979 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01018308 0,03613641 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01018308 0,03608319 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01018308 0,03603013 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01018308 0,03597722 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01018308 0,03592447 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01018308 0,03587187 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01018308 0,03581942 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01018308 0,03576713 ! lymph node development GO:0048535 10 7 0,000 0,01018308 0,03571499 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01018308 0,03566301 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01018308 0,03561117 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01018308 0,03555949 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01018308 0,03550795 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01018308 0,03545656 ! adult feeding behavior GO:0008343 9 7 0,000 0,01018308 0,03540533 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01018308 0,03535424 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01018308 0,03530329 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01018308 0,0352525 ! muscle adaptation GO:0043500 14 7 0,000 0,01018308 0,03520185 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01018308 0,03515134 ! retina homeostasis GO:0001895 12 7 0,000 0,01018308 0,03510098 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01018308 0,03505077 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01018308 0,03500069 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01018308 0,03495076 ! protein prenylation GO:0018342 18 7 0,000 0,01018308 0,03490098 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01018308 0,03485133 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01018308 0,03480183 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01018308 0,03475246 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01162951 0,03963257 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01162951 0,03957651 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01162951 0,03952061 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01162951 0,03946487 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01162951 0,03940928 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01162951 0,03935386 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01162951 0,03929858 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01162951 0,03924347 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01162951 0,0391885 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01162951 0,03913369 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01162951 0,03907904 ! meiotic prophase I GO:0007128 13 8 0,000 0,01162951 0,03902453 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01162951 0,03897018 ! oligopeptide transport GO:0006857 15 8 0,000 0,01162951 0,03891598 ! UTP metabolic process GO:0046051 8 8 0,000 0,01162951 0,03886193 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01162951 0,03880803 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01162951 0,03875428 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01162951 0,03870068 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01162951 0,03864723 ! succinate metabolic process GO:0006105 14 8 0,000 0,01162951 0,03859392 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01162951 0,03854076 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01162951 0,03848775 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01162951 0,03843488 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01162951 0,03838216 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01162951 0,03832958 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01162951 0,03827714 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01162951 0,03822485 ! reflex GO:0060004 16 8 0,000 0,01162951 0,0381727 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01162951 0,0381207 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01162951 0,03806883 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01162951 0,03801711 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01162951 0,03796552 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01162951 0,03791408 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01162951 0,03786278 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01162951 0,03781161 ! pigment granule organization GO:0048753 16 8 0,000 0,01162951 0,03776058 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01162951 0,03770969 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01162951 0,03765894 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01162951 0,03760832 ! histidine metabolic process GO:0006547 16 8 0,000 0,01162951 0,03755784 GO:0009075|histidine family amino acid metabolic process, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01162951 0,0375075 ! glycine catabolic process GO:0006546 13 8 0,000 0,01162951 0,03745728 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01162951 0,03740721 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01162951 0,03735727 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01162951 0,03730746 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01162951 0,03725778 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01162951 0,03720823 ! melanin metabolic process GO:0006582 15 8 0,000 0,01162951 0,03715882 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01162951 0,03710954 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01162951 0,03706039 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01162951 0,03701136 ! macrophage activation GO:0042116 12 8 0,000 0,01162951 0,03696247 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01162951 0,03691371 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01162951 0,03686507 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01162951 0,03681657 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01162951 0,03676819 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01162951 0,03671994 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01162951 0,03667181 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01162951 0,03662381 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01162951 0,03657594 ! osteoblast development GO:0002076 16 8 0,000 0,01162951 0,03652819 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01162951 0,03648056 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01162951 0,03643306 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01162951 0,03638568 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01162951 0,03633843 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01162951 0,0362913 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01162951 0,03624429 ! response to UV-B GO:0010224 16 8 0,000 0,01162951 0,0361974 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01162951 0,03615064 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01162951 0,03610399 ! intermediate filament organization GO:0045109 12 8 0,000 0,01162951 0,03605746 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01162951 0,03601106 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01162951 0,03596477 ! cellular extravasation GO:0045123 12 8 0,000 0,01162951 0,0359186 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01162951 0,03587255 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01162951 0,03582662 ! response to antibiotic GO:0046677 11 8 0,000 0,01162951 0,03578081 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01162951 0,03573511 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01162951 0,03568953 ! DNA topological change GO:0006265 12 8 0,000 0,01162951 0,03564407 ! response to tropane GO:0014073 15 8 0,000 0,01162951 0,03559872 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01162951 0,03555348 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01162951 0,03550836 ! melanosome transport GO:0032402 13 8 0,000 0,01162951 0,03546336 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01162951 0,03541847 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01162951 0,03537369 ! mast cell activation GO:0045576 14 8 0,000 0,01162951 0,03532903 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01162951 0,03528448 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01162951 0,03524004 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01162951 0,03519571 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01162951 0,0351515 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01162951 0,03510739 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01162951 0,0350634 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01162951 0,03501951 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01162951 0,03497574 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01162951 0,03493207 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01162951 0,03488852 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01162951 0,03484507 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01162951 0,03480173 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01162951 0,0347585 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01162951 0,03471537 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01162951 0,03467236 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01162951 0,03462944 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01162951 0,03458664 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01162951 0,03454394 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01162951 0,03450135 ! hormone catabolic process GO:0042447 17 8 0,000 0,01162951 0,03445886 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01162951 0,03441647 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01162951 0,03437419 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01162951 0,03433201 ! ATP catabolic process GO:0006200 11 8 0,000 0,01162951 0,03428994 ! blastocyst growth GO:0001832 19 8 0,000 0,01162951 0,03424797 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01162951 0,0342061 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01162951 0,03416434 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01162951 0,03412267 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01162951 0,03408111 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01162951 0,03403965 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01162951 0,03399829 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01162951 0,03395703 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01162951 0,03391587 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01162951 0,03387481 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01162951 0,03383385 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01162951 0,03379298 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01162951 0,03375222 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01162951 0,03371156 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01162951 0,03367099 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01162951 0,03363052 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01162951 0,03359015 ! axon extension GO:0048675 15 9 0,000 0,01307387 0,0377167 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01307387 0,03767153 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01307387 0,03762647 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01307387 0,03758151 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01307387 0,03753667 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01307387 0,03749193 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01307387 0,03744729 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01307387 0,03740277 ! phosphate transport GO:0006817 19 9 0,000 0,01307387 0,03735835 ! reproductive behavior GO:0019098 19 9 0,000 0,01307387 0,03731403 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01307387 0,03726982 ! CTP metabolic process GO:0046036 9 9 0,000 0,01307387 0,03722571 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01307387 0,03718171 ! GTP metabolic process GO:0046039 9 9 0,000 0,01307387 0,03713781 ! RNA methylation GO:0001510 15 9 0,000 0,01307387 0,03709402 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01307387 0,03705033 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01307387 0,03700674 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01307387 0,03696325 ! artery development GO:0060840 24 9 0,000 0,01307387 0,03691987 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01307387 0,03687658 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01307387 0,0368334 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01307387 0,03679032 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01307387 0,03674734 ! chemosensory behavior GO:0007635 20 9 0,000 0,01307387 0,03670447 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01307387 0,03666169 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01307387 0,03661901 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01307387 0,03657643 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01307387 0,03653395 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01307387 0,03649156 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01307387 0,03644928 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01307387 0,03640709 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01307387 0,036365 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01307387 0,03632301 ! protein targeting to ER GO:0045047 22 9 0,000 0,01307387 0,03628112 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01307387 0,03623932 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01307387 0,03619761 ! T cell selection GO:0045058 23 9 0,000 0,01307387 0,03615601 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01307387 0,0361145 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01307387 0,03607308 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01307387 0,03603176 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01307387 0,03599053 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01307387 0,0359494 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01307387 0,03590836 ! mannose metabolic process GO:0006013 13 9 0,000 0,01307387 0,03586742 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01307387 0,03582657 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01307387 0,03578581 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01307387 0,03574514 ! receptor clustering GO:0043113 18 9 0,000 0,01307387 0,03570457 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01307387 0,03566409 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01307387 0,0356237 ! ruffle organization GO:0031529 15 9 0,000 0,01307387 0,0355834 ! retinol metabolic process GO:0042572 18 9 0,000 0,01307387 0,03554319 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01307387 0,03550308 ! behavioral fear response GO:0001662 22 9 0,000 0,01307387 0,03546305 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01307387 0,03542312 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01307387 0,03538327 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01307387 0,03534351 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01307387 0,03530385 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01307387 0,03526427 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01307387 0,03522478 ! segment specification GO:0007379 13 9 0,000 0,01307387 0,03518538 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01307387 0,03514606 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01307387 0,03510684 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01307387 0,0350677 ! response to amine stimulus GO:0014075 13 9 0,000 0,01307387 0,03502865 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01307387 0,03498969 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01307387 0,03495081 ! erythrocyte development GO:0048821 15 9 0,000 0,01307387 0,03491202 ! gas homeostasis GO:0033483 16 9 0,000 0,01307387 0,03487331 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01307387 0,03483469 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01307387 0,03479616 ! renal water homeostasis GO:0003091 14 9 0,000 0,01307387 0,03475771 ! postreplication repair GO:0006301 22 9 0,000 0,01307387 0,03471935 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01307387 0,03468107 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01307387 0,03464287 ! icosanoid secretion GO:0032309 15 9 0,000 0,01307387 0,03460476 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01307387 0,03456673 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01307387 0,03452879 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01307387 0,03449093 ! regulation of cell division GO:0051302 15 9 0,000 0,01307387 0,03445315 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01307387 0,03441546 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01307387 0,03437784 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01307387 0,03434031 ! sterol catabolic process GO:0016127 11 9 0,000 0,01307387 0,03430286 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01307387 0,0342655 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01307387 0,03422821 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01307387 0,03419101 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01307387 0,03415388 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01307387 0,03411684 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01307387 0,03407988 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01307387 0,03404299 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01307387 0,03400619 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01307387 0,03396947 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01307387 0,03393282 ! purine base metabolic process GO:0006144 21 9 0,000 0,01307387 0,03389626 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01307387 0,03385977 ! pigment granule transport GO:0051904 17 9 0,000 0,01307387 0,03382336 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01307387 0,03378703 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01307387 0,03375078 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01307387 0,03371461 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01307387 0,03367851 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01307387 0,03364249 ! mitochondrion localization GO:0051646 15 9 0,000 0,01307387 0,03360655 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01451617 0,03727417 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01451617 0,03723443 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01451617 0,03719478 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01451617 0,03715521 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01451617 0,03711573 ! synapsis GO:0007129 13 10 0,000 0,01451617 0,03707633 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01451617 0,03703701 ! N-glycan processing GO:0006491 20 10 0,000 0,01451617 0,03699777 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01451617 0,03695862 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01451617 0,03691956 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01451617 0,03688057 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01451617 0,03684167 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01451617 0,03680284 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01451617 0,0367641 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01451617 0,03672545 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01451617 0,03668687 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01451617 0,03664837 ! androgen metabolic process GO:0008209 17 10 0,000 0,01451617 0,03660996 ! phospholipid efflux GO:0033700 16 10 0,000 0,01451617 0,03657162 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01451617 0,03653337 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01451617 0,03649519 ! lung alveolus development GO:0048286 26 10 0,000 0,01451617 0,0364571 ! pathogenesis GO:0009405 13 10 0,000 0,01451617 0,03641908 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01451617 0,03638115 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01451617 0,03634329 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01451617 0,03630551 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01451617 0,03626781 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01451617 0,03623019 ! endoderm development GO:0007492 16 10 0,000 0,01451617 0,03619264 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01451617 0,03615518 ! arginine catabolic process GO:0006527 13 10 0,000 0,01451617 0,03611779 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01451617 0,03608047 ! proline metabolic process GO:0006560 13 10 0,000 0,01451617 0,03604324 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01451617 0,03600608 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01451617 0,035969 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01451617 0,035932 ! V(D)J recombination GO:0033151 28 10 0,000 0,01451617 0,03589507 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01451617 0,03585821 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01451617 0,03582144 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01451617 0,03578473 ! B cell proliferation GO:0042100 18 10 0,000 0,01451617 0,03574811 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01451617 0,03571155 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01451617 0,03567508 ! multicellular organism growth GO:0035264 18 10 0,000 0,01451617 0,03563867 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01451617 0,03560234 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01451617 0,03556609 ! epithelial cell development GO:0002064 20 10 0,000 0,01451617 0,03552991 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01451617 0,0354938 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01451617 0,03545777 ! macroautophagy GO:0016236 17 10 0,000 0,01451617 0,0354218 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01451617 0,03538592 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01451617 0,0353501 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01451617 0,03531436 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01451617 0,03527869 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01451617 0,03524309 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01451617 0,03520756 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01451617 0,0351721 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01451617 0,03513672 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01451617 0,03510141 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01451617 0,03506616 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01451617 0,03503099 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01451617 0,03499589 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01451617 0,03496086 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01451617 0,0349259 ! response to dsRNA GO:0043331 20 10 0,000 0,01451617 0,03489101 ! DNA ligation GO:0006266 19 10 0,000 0,01451617 0,03485619 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01451617 0,03482144 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01451617 0,03478675 ! melanosome localization GO:0032400 16 10 0,000 0,01451617 0,03475214 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01451617 0,03471759 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01451617 0,03468312 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01451617 0,03464871 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01451617 0,03461437 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01451617 0,0345801 ! mRNA cleavage GO:0006379 17 10 0,000 0,01451617 0,03454589 ! protein sumoylation GO:0016925 15 10 0,000 0,01451617 0,03451176 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01451617 0,03447769 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01451617 0,03444369 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01451617 0,03440975 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01451617 0,03437589 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01451617 0,03434208 ! salivary gland development GO:0007431 27 10 0,000 0,01451617 0,03430835 ! prophase GO:0051324 15 10 0,000 0,01451617 0,03427468 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01451617 0,03424108 ! apical protein localization GO:0045176 15 10 0,000 0,01451617 0,03420754 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01451617 0,03417407 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01451617 0,03414066 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01451617 0,03410732 ! midbrain development GO:0030901 13 10 0,000 0,01451617 0,03407405 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01451617 0,03404084 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01451617 0,03400769 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01451617 0,03397461 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01451617 0,03394159 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01451617 0,03390864 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01451617 0,03387575 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01451617 0,03384293 ! detection of calcium ion GO:0005513 23 10 0,000 0,01451617 0,03381016 ! oocyte development GO:0048599 17 10 0,000 0,01451617 0,03377747 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01451617 0,03374483 ! blastocyst formation GO:0001825 17 10 0,000 0,01451617 0,03371226 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01451617 0,03367975 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01451617 0,0336473 ! activation of innate immune response GO:0002218 12 10 0,000 0,01451617 0,03361492 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01451617 0,0335826 ! response to nicotine GO:0035094 20 10 0,000 0,01451617 0,03355034 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01451617 0,03351814 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01451617 0,033486 ! localization within membrane GO:0051668 20 10 0,000 0,01451617 0,03345393 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01595641 0,03673791 ! respiratory burst GO:0045730 17 11 0,000 0,01595641 0,03670279 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01595641 0,03666773 ! neuron fate specification GO:0048665 17 11 0,000 0,01595641 0,03663274 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01595641 0,03659782 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01595641 0,03656297 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01595641 0,03652818 ! thyroid gland development GO:0030878 26 11 0,000 0,01595641 0,03649346 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01595641 0,0364588 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01595641 0,03642421 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01595641 0,03638968 ! response to pain GO:0048265 24 11 0,000 0,01595641 0,03635522 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01595641 0,03632083 ! T cell proliferation GO:0042098 26 11 0,000 0,01595641 0,0362865 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01595641 0,03625223 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01595641 0,03621803 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01595641 0,0361839 ! bone resorption GO:0045453 16 11 0,000 0,01595641 0,03614983 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01595641 0,03611582 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01595641 0,03608188 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01595641 0,036048 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01595641 0,03601418 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01595641 0,03598043 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01595641 0,03594674 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01595641 0,03591311 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01595641 0,03587955 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01595641 0,03584605 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01595641 0,03581261 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01595641 0,03577923 ! lipid digestion GO:0044241 18 11 0,000 0,01595641 0,03574592 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01595641 0,03571267 ! UV protection GO:0009650 19 11 0,000 0,01595641 0,03567948 ! adult heart development GO:0007512 14 11 0,000 0,01595641 0,03564635 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01595641 0,03561328 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01595641 0,03558027 ! temperature homeostasis GO:0001659 17 11 0,000 0,01595641 0,03554733 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01595641 0,03551445 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01595641 0,03548162 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01595641 0,03544886 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01595641 0,03541616 ! regulation of organ growth GO:0046620 13 11 0,000 0,01595641 0,03538352 ! pigment granule localization GO:0051875 20 11 0,000 0,01595641 0,03535093 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01595641 0,03531841 ! vasoconstriction GO:0042310 18 11 0,000 0,01595641 0,03528595 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01595641 0,03525355 ! embryonic axis specification GO:0000578 18 11 0,000 0,01595641 0,03522121 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01595641 0,03518892 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01595641 0,0351567 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01595641 0,03512453 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01595641 0,03509243 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01595641 0,03506038 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01595641 0,03502839 ! zymogen activation GO:0031638 15 11 0,000 0,01595641 0,03499646 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01595641 0,03496459 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01595641 0,03493277 ! nucleosome positioning GO:0016584 15 11 0,000 0,01595641 0,03490101 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01595641 0,03486931 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01595641 0,03483767 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01595641 0,03480609 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01595641 0,03477456 ! acid secretion GO:0046717 18 11 0,000 0,01595641 0,03474309 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01595641 0,03471168 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01595641 0,03468032 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01595641 0,03464902 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01595641 0,03461778 ! oocyte differentiation GO:0009994 18 11 0,000 0,01595641 0,03458659 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01595641 0,03455546 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01595641 0,03452438 ! cholesterol efflux GO:0033344 19 11 0,000 0,01595641 0,03449337 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01595641 0,0344624 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01595641 0,03443149 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01595641 0,03440064 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01595641 0,03436984 ! embryonic gut development GO:0048566 15 11 0,000 0,01595641 0,0343391 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01595641 0,03430841 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01595641 0,03427778 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01595641 0,0342472 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01595641 0,03421668 ! defense response to fungus GO:0050832 13 11 0,000 0,01595641 0,03418621 ! developmental induction GO:0031128 19 11 0,000 0,01595641 0,0341558 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01595641 0,03412544 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01595641 0,03409513 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01595641 0,03406488 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01595641 0,03403468 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01595641 0,03400453 ! nucleus localization GO:0051647 19 11 0,000 0,01595641 0,03397444 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01595641 0,0339444 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01739459 0,03697119 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01739459 0,03693855 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01739459 0,03690598 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01739459 0,03687346 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01739459 0,03684101 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01739459 0,0368086 ! cartilage condensation GO:0001502 20 12 0,000 0,01739459 0,03677626 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01739459 0,03674397 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01739459 0,03671174 ! protein complex disassembly GO:0043241 27 12 0,000 0,01739459 0,03667956 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01739459 0,03664744 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01739459 0,03661538 ! hippocampus development GO:0021766 26 12 0,000 0,01739459 0,03658338 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01739459 0,03655143 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01739459 0,03651953 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01739459 0,03648769 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01739459 0,03645591 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01739459 0,03642418 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01739459 0,03639251 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01739459 0,03636089 ! drug transport GO:0015893 16 12 0,000 0,01739459 0,03632932 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01739459 0,03629782 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01739459 0,03626636 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01739459 0,03623496 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01739459 0,03620362 ! focal adhesion formation GO:0048041 35 12 0,000 0,01739459 0,03617233 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01739459 0,03614109 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01739459 0,03610991 ! forebrain cell migration GO:0021885 21 12 0,000 0,01739459 0,03607878 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01739459 0,0360477 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01739459 0,03601668 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01739459 0,03598571 ! entry into host cell GO:0030260 32 12 0,000 0,01739459 0,0359548 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01739459 0,03592393 ! monoamine transport GO:0015844 18 12 0,000 0,01739459 0,03589312 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01739459 0,03586237 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01739459 0,03583166 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01739459 0,03580101 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01739459 0,03577041 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01739459 0,03573987 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01739459 0,03570937 ! protein homotetramerization GO:0051289 21 12 0,000 0,01739459 0,03567893 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01739459 0,03564854 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01739459 0,0356182 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01739459 0,03558791 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01739459 0,03555767 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01739459 0,03552749 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01739459 0,03549736 ! cranial nerve development GO:0021545 20 12 0,000 0,01739459 0,03546727 ! fucose catabolic process GO:0019317 22 12 0,000 0,01739459 0,03543724 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01739459 0,03540726 ! histone acetylation GO:0016573 26 12 0,000 0,01739459 0,03537733 ! histone methylation GO:0016571 26 12 0,000 0,01739459 0,03534745 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01739459 0,03531762 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01739459 0,03528784 ! gland morphogenesis GO:0022612 29 12 0,000 0,01739459 0,03525811 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01739459 0,03522844 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01739459 0,03519881 ! T cell homeostasis GO:0043029 25 12 0,000 0,01739459 0,03516923 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01739459 0,0351397 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01739459 0,03511022 ! spleen development GO:0048536 22 12 0,000 0,01739459 0,03508079 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01739459 0,03505141 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01739459 0,03502208 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01739459 0,03499279 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01739459 0,03496356 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01739459 0,03493438 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01739459 0,03490524 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01739459 0,03487615 ! response to cold GO:0009409 17 12 0,000 0,01739459 0,03484711 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01739459 0,03481812 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01739459 0,03478918 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01883072 0,03763015 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01883072 0,03759893 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01883072 0,03756775 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01883072 0,03753663 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01883072 0,03750555 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01883072 0,03747453 ! lipid localization GO:0010876 28 13 0,000 0,01883072 0,03744356 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01883072 0,03741264 ! organelle fusion GO:0048284 32 13 0,000 0,01883072 0,03738177 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01883072 0,03735095 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01883072 0,03732019 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01883072 0,03728947 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01883072 0,0372588 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01883072 0,03722819 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01883072 0,03719762 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01883072 0,03716711 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01883072 0,03713664 ! methionine metabolic process GO:0006555 27 13 0,000 0,01883072 0,03710623 ! plasma membrane organization GO:0007009 24 13 0,000 0,01883072 0,03707586 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01883072 0,03704555 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01883072 0,03701528 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01883072 0,03698507 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01883072 0,0369549 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01883072 0,03692478 ! response to X-ray GO:0010165 25 13 0,000 0,01883072 0,03689471 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01883072 0,03686469 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01883072 0,03683472 ! exocrine system development GO:0035272 32 13 0,000 0,01883072 0,0368048 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01883072 0,03677492 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01883072 0,0367451 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01883072 0,03671532 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01883072 0,03668559 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01883072 0,03665591 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01883072 0,03662628 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01883072 0,03659669 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01883072 0,03656716 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01883072 0,03653767 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01883072 0,03650822 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01883072 0,03647883 ! ribosome assembly GO:0042255 17 13 0,000 0,01883072 0,03644948 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01883072 0,03642018 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01883072 0,03639093 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01883072 0,03636172 ! chromatin silencing GO:0006342 26 13 0,000 0,01883072 0,03633256 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01883072 0,03630345 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01883072 0,03627438 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01883072 0,03624537 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01883072 0,03621639 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01883072 0,03618747 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01883072 0,03615858 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01883072 0,03612975 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01883072 0,03610096 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01883072 0,03607222 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01883072 0,03604352 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01883072 0,03601487 ! embryonic placenta development GO:0001892 23 13 0,000 0,01883072 0,03598626 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01883072 0,0359577 ! insulin secretion GO:0030073 23 13 0,000 0,01883072 0,03592919 ! actin filament polymerization GO:0030041 24 13 0,000 0,01883072 0,03590072 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01883072 0,03587229 ! acrosome reaction GO:0007340 18 13 0,000 0,01883072 0,03584391 ! rRNA transcription GO:0009303 25 14 0,000 0,02026479 0,03854316 ! lactation GO:0007595 26 14 0,000 0,02026479 0,03851271 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02026479 0,03848232 ! reproductive cellular process GO:0048610 20 14 0,000 0,02026479 0,03845197 ! tRNA modification GO:0006400 20 14 0,000 0,02026479 0,03842167 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02026479 0,03839141 ! regulation of S phase GO:0033261 23 14 0,000 0,02026479 0,03836121 ! water transport GO:0006833 21 14 0,000 0,02026479 0,03833105 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02026479 0,03830094 ! non-recombinational repair GO:0000726 25 14 0,000 0,02026479 0,03827088 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02026479 0,03824086 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02026479 0,03821089 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02026479 0,03818097 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02026479 0,03815109 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02026479 0,03812126 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02026479 0,03809148 ! palate development GO:0060021 31 14 0,000 0,02026479 0,03806174 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02026479 0,03803206 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02026479 0,03800241 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02026479 0,03797282 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02026479 0,03794326 ! arginine metabolic process GO:0006525 17 14 0,000 0,02026479 0,03791376 ! regulation of heart rate GO:0002027 24 14 0,000 0,02026479 0,0378843 ! organic alcohol transport GO:0015850 29 14 0,000 0,02026479 0,03785489 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02026479 0,03782552 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02026479 0,0377962 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02026479 0,03776692 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02026479 0,03773769 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02026479 0,0377085 ! L-amino acid transport GO:0015807 30 14 0,000 0,02026479 0,03767936 ! stem cell development GO:0048864 43 14 0,000 0,02026479 0,03765027 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02026479 0,03762122 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02026479 0,03759221 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02026479 0,03756325 ! cerebellum development GO:0021549 21 14 0,000 0,02026479 0,03753433 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02026479 0,03750546 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02026479 0,03747663 ! response to gamma radiation GO:0010332 28 14 0,000 0,02026479 0,03744785 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02026479 0,03741911 ! cofactor transport GO:0051181 26 14 0,000 0,02026479 0,03739041 ! NADP metabolic process GO:0006739 24 14 0,000 0,02026479 0,03736176 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02026479 0,03733315 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02026479 0,03730459 ! intestinal absorption GO:0050892 25 14 0,000 0,02026479 0,03727607 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02026479 0,03724759 ! oxygen transport GO:0015671 21 14 0,000 0,02026479 0,03721916 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02026479 0,03719077 ! male genitalia development GO:0030539 24 14 0,000 0,02026479 0,03716242 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02026479 0,03713412 ! regulation of axon extension GO:0030516 37 14 0,000 0,02026479 0,03710586 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02026479 0,03707764 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02026479 0,03704946 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02169682 0,03963748 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02169682 0,0396074 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02169682 0,03957737 ! superoxide anion generation GO:0042554 20 15 0,000 0,02169682 0,03954739 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02169682 0,03951745 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02169682 0,03948756 ! copper ion transport GO:0006825 20 15 0,000 0,02169682 0,03945771 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02169682 0,03942791 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02169682 0,03939816 ! sulfate transport GO:0008272 23 15 0,000 0,02169682 0,03936844 ! response to cAMP GO:0051591 22 15 0,000 0,02169682 0,03933878 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02169682 0,03930915 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02169682 0,03927958 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02169682 0,03925004 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02169682 0,03922055 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02169682 0,03919111 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02169682 0,03916171 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02169682 0,03913235 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02169682 0,03910304 ! pituitary gland development GO:0021983 29 15 0,000 0,02169682 0,03907377 ! vesicle coating GO:0006901 33 15 0,000 0,02169682 0,03904454 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02169682 0,03901536 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02169682 0,03898623 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02169682 0,03895713 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02169682 0,03892808 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02169682 0,03889907 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02169682 0,03887011 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02169682 0,03884119 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02169682 0,03881231 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02169682 0,03878347 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02169682 0,03875468 ! histone deacetylation GO:0016575 20 15 0,000 0,02169682 0,03872593 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02169682 0,03869722 ! tissue regeneration GO:0042246 26 15 0,000 0,02169682 0,03866856 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02169682 0,03863994 ! water homeostasis GO:0030104 27 15 0,000 0,02169682 0,03861136 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02169682 0,03858282 ! muscle maintenance GO:0046716 26 15 0,000 0,02169682 0,03855432 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02169682 0,03852587 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02169682 0,03849746 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02169682 0,03846909 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02169682 0,03844076 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02169682 0,03841248 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02169682 0,03838423 ! detection of bacterium GO:0016045 18 15 0,000 0,02169682 0,03835603 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02169682 0,03832787 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02169682 0,03829975 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02169682 0,03827167 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02169682 0,03824363 ! peptide hormone processing GO:0016486 23 15 0,000 0,02169682 0,03821563 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02312681 0,04070453 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02312681 0,04067478 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02312681 0,04064506 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02312681 0,0406154 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02312681 0,04058577 ! bone remodeling GO:0046849 27 16 0,000 0,02312681 0,04055619 ! filopodium assembly GO:0046847 32 16 0,000 0,02312681 0,04052665 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02312681 0,04049716 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02312681 0,0404677 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02312681 0,04043829 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02312681 0,04040893 ! startle response GO:0001964 28 16 0,000 0,02312681 0,0403796 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02312681 0,04035032 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02312681 0,04032108 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02312681 0,04029189 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02312681 0,04026273 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02312681 0,04023362 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02312681 0,04020455 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02312681 0,04017552 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02312681 0,04014653 ! response to osmotic stress GO:0006970 25 16 0,000 0,02312681 0,04011759 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02312681 0,04008868 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02312681 0,04005982 ! fructose metabolic process GO:0006000 25 16 0,000 0,02312681 0,040031 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02312681 0,04000222 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02312681 0,03997349 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02312681 0,03994479 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02312681 0,03991614 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02312681 0,03988752 ! axon cargo transport GO:0008088 43 16 0,000 0,02312681 0,03985895 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02312681 0,03983042 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02312681 0,03980193 ! DNA replication initiation GO:0006270 27 16 0,000 0,02312681 0,03977348 ! neuron recognition GO:0008038 35 16 0,000 0,02312681 0,03974507 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02312681 0,0397167 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02312681 0,03968837 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02312681 0,03966008 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02312681 0,03963183 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02312681 0,03960363 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02312681 0,03957546 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02312681 0,03954733 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02312681 0,03951924 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02312681 0,0394912 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02312681 0,03946319 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02312681 0,03943522 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02312681 0,03940729 ! defense response to virus GO:0051607 37 16 0,000 0,02312681 0,0393794 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02455475 0,04178127 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02455475 0,04175174 ! metencephalon development GO:0022037 30 17 0,000 0,02455475 0,04172226 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02455475 0,04169281 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02455475 0,04166341 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02455475 0,04163405 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02455475 0,04160473 ! signal complex assembly GO:0007172 41 17 0,000 0,02455475 0,04157545 ! endothelial cell migration GO:0043542 28 17 0,000 0,02455475 0,04154621 ! inositol metabolic process GO:0006020 28 17 0,000 0,02455475 0,04151702 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02455475 0,04148786 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02455475 0,04145875 ! glial cell development GO:0021782 27 17 0,000 0,02455475 0,04142968 ! limbic system development GO:0021761 36 17 0,000 0,02455475 0,04140064 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02455475 0,04137165 ! adult walking behavior GO:0007628 33 17 0,000 0,02455475 0,0413427 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02455475 0,04131379 ! heart looping GO:0001947 30 17 0,000 0,02455475 0,04128492 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02455475 0,04125609 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02455475 0,0412273 ! myoblast differentiation GO:0045445 45 17 0,000 0,02455475 0,04119855 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02455475 0,04116984 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02455475 0,04114117 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02455475 0,04111254 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02455475 0,04108395 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02455475 0,0410554 ! glycine metabolic process GO:0006544 28 17 0,000 0,02455475 0,04102689 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02455475 0,04099842 ! NAD metabolic process GO:0019674 29 17 0,000 0,02455475 0,04096998 ! membrane budding GO:0006900 37 17 0,000 0,02455475 0,04094159 ! DNA integration GO:0015074 29 17 0,000 0,02455475 0,04091324 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02455475 0,04088493 ! regulation of protein binding GO:0043393 33 17 0,000 0,02455475 0,04085665 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02455475 0,04082842 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02455475 0,04080022 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02455475 0,04077206 ! genitalia development GO:0048806 30 17 0,000 0,02455475 0,04074394 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02455475 0,04071586 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02455475 0,04068782 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02455475 0,04065982 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02455475 0,04063186 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02455475 0,04060393 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02455475 0,04057604 ! steroid catabolic process GO:0006706 31 17 0,000 0,02455475 0,04054819 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02455475 0,04052038 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02455475 0,04049261 ! gas transport GO:0015669 25 17 0,000 0,02455475 0,04046487 ! organic cation transport GO:0015695 31 17 0,000 0,02455475 0,04043718 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02455475 0,04040952 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02455475 0,0403819 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02455475 0,04035432 ! microspike assembly GO:0030035 36 17 0,000 0,02455475 0,04032677 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02455475 0,04029926 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02455475 0,04027179 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02598065 0,04258136 ! neuron maturation GO:0042551 42 18 0,000 0,02598065 0,04255237 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02598065 0,04252342 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02598065 0,04249452 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02598065 0,04246565 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02598065 0,04243682 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02598065 0,04240803 ! memory GO:0007613 31 18 0,000 0,02598065 0,04237928 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02598065 0,04235056 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02598065 0,04232189 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02598065 0,04229326 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02598065 0,04226466 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02598065 0,0422361 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02598065 0,04220758 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02598065 0,0421791 ! response to retinoic acid GO:0032526 26 18 0,000 0,02598065 0,04215066 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02598065 0,04212226 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02598065 0,04209389 ! response to fungus GO:0009620 21 18 0,000 0,02598065 0,04206557 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02598065 0,04203728 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02598065 0,04200903 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02598065 0,04198081 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02598065 0,04195264 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02598065 0,0419245 ! vitamin transport GO:0051180 27 18 0,000 0,02598065 0,0418964 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02598065 0,04186834 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02598065 0,04184032 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02598065 0,04181233 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02598065 0,04178438 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02598065 0,04175647 ! nerve development GO:0021675 28 18 0,000 0,02598065 0,04172859 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02598065 0,04170076 ! protein secretion GO:0009306 39 19 0,000 0,02740451 0,04395683 ! positive regulation of translation GO:0045727 30 19 0,000 0,02740451 0,04392755 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02740451 0,0438983 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02740451 0,04386909 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02740451 0,04383993 ! skin development GO:0043588 36 19 0,000 0,02740451 0,0438108 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02740451 0,0437817 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02740451 0,04375265 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02740451 0,04372364 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02740451 0,04369466 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02740451 0,04366573 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02740451 0,04363683 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02740451 0,04360797 ! cerebral cortex development GO:0021987 36 19 0,000 0,02740451 0,04357915 ! pigmentation during development GO:0048066 41 19 0,000 0,02740451 0,04355036 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,02740451 0,04352162 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,02740451 0,04349291 ! heme metabolic process GO:0042168 36 19 0,000 0,02740451 0,04346424 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02740451 0,0434356 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02740451 0,04340701 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02740451 0,04337845 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02740451 0,04334993 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02740451 0,04332145 ! peptide cross-linking GO:0018149 37 19 0,000 0,02740451 0,04329301 ! protein export from nucleus GO:0006611 36 19 0,000 0,02740451 0,0432646 ! heart process GO:0003015 30 19 0,000 0,02740451 0,04323623 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02740451 0,04320789 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02740451 0,0431796 ! visual learning GO:0008542 36 19 0,000 0,02740451 0,04315134 ! cellular pigmentation GO:0033059 36 19 0,000 0,02740451 0,04312312 ! G1 phase GO:0051318 40 19 0,000 0,02740451 0,04309493 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02740451 0,04306678 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02740451 0,04303867 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02740451 0,0430106 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02740451 0,04298256 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02740451 0,04295456 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02740451 0,04292659 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02740451 0,04289866 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02740451 0,04287077 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02740451 0,04284292 ! cilium assembly GO:0042384 37 19 0,000 0,02740451 0,0428151 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02740451 0,04278731 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02882634 0,04497806 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02882634 0,04494891 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02882634 0,0449198 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02882634 0,04489072 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02882634 0,04486169 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02882634 0,04483269 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02882634 0,04480373 ! response to vitamin GO:0033273 31 20 0,000 0,02882634 0,0447748 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02882634 0,04474591 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02882634 0,04471706 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02882634 0,04468825 ! response to alkaloid GO:0043279 38 20 0,000 0,02882634 0,04465948 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02882634 0,04463074 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02882634 0,04460204 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02882634 0,04457337 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02882634 0,04454474 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02882634 0,04451615 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02882634 0,0444876 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02882634 0,04445908 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02882634 0,0444306 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02882634 0,04440216 ! body fluid secretion GO:0007589 31 20 0,000 0,02882634 0,04437375 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02882634 0,04434538 ! peptide secretion GO:0002790 35 20 0,000 0,02882634 0,04431704 ! stem cell differentiation GO:0048863 53 20 0,000 0,02882634 0,04428874 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02882634 0,04426048 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02882634 0,04423225 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02882634 0,04420406 ! sensory perception of pain GO:0019233 30 20 0,000 0,02882634 0,0441759 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02882634 0,04414778 ! diencephalon development GO:0021536 34 20 0,000 0,02882634 0,0441197 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02882634 0,04409165 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02882634 0,04406364 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02882634 0,04403566 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,02882634 0,04400772 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02882634 0,04397981 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02882634 0,04395194 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02882634 0,04392411 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02882634 0,04389631 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02882634 0,04386854 ! regulation of glucose import GO:0046324 29 20 0,000 0,02882634 0,04384081 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02882634 0,04381312 ! actin filament-based movement GO:0030048 43 20 0,000 0,02882634 0,04378546 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02882634 0,04375783 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02882634 0,04373024 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02882634 0,04370269 ! negative regulation of translation GO:0017148 29 20 0,000 0,02882634 0,04367517 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02882634 0,04364768 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02882634 0,04362023 ! regulation of cell killing GO:0031341 42 21 0,000 0,03024613 0,04573991 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03024613 0,04571118 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03024613 0,04568249 ! hormone secretion GO:0046879 38 21 0,000 0,03024613 0,04565383 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03024613 0,0456252 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03024613 0,04559662 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03024613 0,04556806 ! axis specification GO:0009798 38 21 0,000 0,03024613 0,04553955 ! ovarian follicle development GO:0001541 35 21 0,000 0,03024613 0,04551107 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03024613 0,04548262 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03024613 0,04545422 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03024613 0,04542584 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03024613 0,0453975 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03024613 0,0453692 ! cell aging GO:0007569 44 21 0,000 0,03024613 0,04534093 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03024613 0,0453127 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03024613 0,04528451 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03024613 0,04525634 ! cytolysis GO:0019835 24 21 0,000 0,03024613 0,04522822 ! vasodilation GO:0042311 39 21 0,000 0,03024613 0,04520012 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03024613 0,04517207 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03024613 0,04514404 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03024613 0,04511606 ! oogenesis GO:0048477 36 21 0,000 0,03024613 0,0450881 ! DNA modification GO:0006304 34 21 0,000 0,03024613 0,04506019 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03024613 0,0450323 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03024613 0,04500445 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03024613 0,04497664 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03024613 0,04494886 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03024613 0,04492111 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03024613 0,0448934 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03024613 0,04486572 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03024613 0,04483808 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03024613 0,04481047 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03024613 0,04478289 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03024613 0,04475535 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03024613 0,04472784 ! gut development GO:0048565 39 21 0,000 0,03024613 0,04470037 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,0316639 0,04676694 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,0316639 0,04673825 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,0316639 0,0467096 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,0316639 0,04668098 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,0316639 0,04665239 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,0316639 0,04662384 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,0316639 0,04659532 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,0316639 0,04656684 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,0316639 0,04653839 ! regeneration GO:0031099 41 22 0,000 0,0316639 0,04650998 ! keratinization GO:0031424 28 22 0,000 0,0316639 0,04648161 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,0316639 0,04645326 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,0316639 0,04642496 ! sensory perception of taste GO:0050909 28 22 0,000 0,0316639 0,04639668 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,0316639 0,04636844 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,0316639 0,04634024 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,0316639 0,04631207 ! vacuolar transport GO:0007034 36 22 0,000 0,0316639 0,04628393 ! lysosome organization GO:0007040 41 22 0,000 0,0316639 0,04625583 ! central nervous system neuron development GO:0021954 46 22 0,000 0,0316639 0,04622776 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,0316639 0,04619973 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,0316639 0,04617173 ! fucose metabolic process GO:0006004 39 22 0,000 0,0316639 0,04614376 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,0316639 0,04611583 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,0316639 0,04608793 ! ureteric bud development GO:0001657 43 22 0,000 0,0316639 0,04606007 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,0316639 0,04603224 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,0316639 0,04600444 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,0316639 0,04597668 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,0316639 0,04594895 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,0316639 0,04592125 ! sarcomere organization GO:0045214 30 22 0,000 0,0316639 0,04589359 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,0316639 0,04586596 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,0316639 0,04583836 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,0316639 0,04581079 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,0316639 0,04578326 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,0316639 0,04575577 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,0316639 0,0457283 ! protein stabilization GO:0050821 39 22 0,000 0,0316639 0,04570087 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03307965 0,04771561 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03307965 0,04768702 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03307965 0,04765846 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03307965 0,04762994 ! gluconeogenesis GO:0006094 33 23 0,000 0,03307965 0,04760145 ! viral genome replication GO:0019079 41 23 0,000 0,03307965 0,047573 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03307965 0,04754458 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03307965 0,0475162 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03307965 0,04748785 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03307965 0,04745953 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03307965 0,04743125 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03307965 0,047403 ! visual behavior GO:0007632 42 23 0,000 0,03307965 0,04737478 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03307965 0,0473466 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03307965 0,04731845 ! response to ethanol GO:0045471 46 23 0,000 0,03307965 0,04729033 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03307965 0,04726225 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03307965 0,0472342 ! peroxisome organization GO:0007031 37 23 0,000 0,03307965 0,04720619 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03307965 0,0471782 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03307965 0,04715025 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03307965 0,04712234 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03307965 0,04709446 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03307965 0,04706661 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03307965 0,04703879 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03307965 0,047011 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03307965 0,04698325 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03307965 0,04695553 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03307965 0,04692785 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03307965 0,04690019 ! fatty acid transport GO:0015908 44 23 0,000 0,03307965 0,04687257 ! platelet activation GO:0030168 37 23 0,000 0,03307965 0,04684498 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03307965 0,04681743 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03307965 0,04678991 ! hormone transport GO:0009914 40 23 0,000 0,03307965 0,04676241 ! cell-cell recognition GO:0009988 25 23 0,000 0,03307965 0,04673496 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03307965 0,04670753 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03307965 0,04668013 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03307965 0,04665277 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03307965 0,04662544 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03307965 0,04659814 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03449337 0,04856117 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03449337 0,04853277 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03449337 0,04850441 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03449337 0,04847607 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03449337 0,04844778 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03449337 0,04841951 ! vesicle docking GO:0048278 47 24 0,000 0,03449337 0,04839128 ! spinal cord development GO:0021510 47 24 0,000 0,03449337 0,04836308 ! vacuole organization GO:0007033 43 24 0,000 0,03449337 0,04833491 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03449337 0,04830678 ! digestive system process GO:0022600 39 24 0,000 0,03449337 0,04827867 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03449337 0,0482506 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03449337 0,04822257 ! regulation of behavior GO:0050795 43 24 0,000 0,03449337 0,04819456 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03449337 0,04816659 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03449337 0,04813865 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03449337 0,04811075 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03449337 0,04808287 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03449337 0,04805503 ! membrane depolarization GO:0051899 39 24 0,000 0,03449337 0,04802722 ! pallium development GO:0021543 49 24 0,000 0,03449337 0,04799944 ! pentose metabolic process GO:0019321 35 24 0,000 0,03449337 0,0479717 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03449337 0,04794399 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03449337 0,0479163 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03449337 0,04788866 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03449337 0,04786104 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03449337 0,04783345 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03449337 0,0478059 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03449337 0,04777838 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03449337 0,04775089 ! regulation of amine transport GO:0051952 40 24 0,000 0,03449337 0,04772343 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03590507 0,04964804 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,03590507 0,04961952 ! myelination GO:0042552 45 25 0,000 0,03590507 0,04959104 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03590507 0,04956259 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03590507 0,04953417 ! phototransduction GO:0007602 33 25 0,000 0,03590507 0,04950578 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03590507 0,04947743 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03590507 0,04944911 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03590507 0,04942082 ! sperm motility GO:0030317 31 25 0,000 0,03590507 0,04939256 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03590507 0,04936434 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03590507 0,04933615 ! receptor metabolic process GO:0043112 46 25 0,000 0,03590507 0,04930799 ! chromosome condensation GO:0030261 45 25 0,000 0,03590507 0,04927986 ! response to starvation GO:0042594 42 25 0,000 0,03590507 0,04925176 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03590507 0,0492237 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,03590507 0,04919567 ! neural crest cell development GO:0014032 54 25 0,000 0,03590507 0,04916767 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03590507 0,0491397 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03590507 0,04911176 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03590507 0,04908386 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03590507 0,04905599 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03590507 0,04902814 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03590507 0,04900033 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03590507 0,04897256 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03590507 0,04894481 ! immunoglobulin production GO:0002377 55 25 0,000 0,03590507 0,0489171 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03590507 0,04888941 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03590507 0,04886176 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03590507 0,04883414 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03590507 0,04880655 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03590507 0,04877899 ! telomere organization GO:0032200 43 25 0,000 0,03590507 0,04875146 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03590507 0,04872397 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03590507 0,0486965 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03731475 0,05057988 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03731475 0,0505514 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03731475 0,05052295 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03731475 0,05049454 ! initiation of viral infection GO:0019059 57 26 0,000 0,03731475 0,05046615 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03731475 0,0504378 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03731475 0,05040948 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03731475 0,05038119 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03731475 0,05035294 ! molting cycle process GO:0022404 50 26 0,000 0,03731475 0,05032471 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03731475 0,05029652 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03731475 0,05026836 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03731475 0,05024023 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03731475 0,05021213 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03731475 0,05018406 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,03731475 0,05015603 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03731475 0,05012802 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03731475 0,05010005 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03731475 0,05007211 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03731475 0,0500442 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03731475 0,05001632 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03731475 0,04998847 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,03731475 0,04996065 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03731475 0,04993286 ! blastocyst development GO:0001824 49 26 0,000 0,03731475 0,04990511 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03731475 0,04987738 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03731475 0,04984969 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03731475 0,04982202 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,03872242 0,05167284 ! neuron fate commitment GO:0048663 48 27 0,000 0,03872242 0,0516442 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03872242 0,05161559 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,03872242 0,05158701 ! iron ion transport GO:0006826 59 27 0,000 0,03872242 0,05155846 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03872242 0,05152994 ! protein amino acid acylation GO:0043543 55 27 0,000 0,03872242 0,05150146 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03872242 0,051473 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03872242 0,05144458 ! fat cell differentiation GO:0045444 50 27 0,000 0,03872242 0,05141619 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03872242 0,05138783 ! autophagy GO:0006914 41 27 0,000 0,03872242 0,0513595 ! male gonad development GO:0008584 44 27 0,000 0,03872242 0,05133121 ! response to toxin GO:0009636 47 27 0,000 0,03872242 0,05130294 ! primary neural tube formation GO:0014020 51 27 0,000 0,03872242 0,0512747 ! base-excision repair GO:0006284 41 27 0,000 0,03872242 0,0512465 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03872242 0,05121833 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03872242 0,05119019 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03872242 0,05116207 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03872242 0,05113399 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03872242 0,05110595 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03872242 0,05107793 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03872242 0,05104994 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03872242 0,05102198 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04012807 0,05284518 ! circadian rhythm GO:0007623 50 28 0,000 0,04012807 0,05281627 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04012807 0,0527874 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04012807 0,05275855 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04012807 0,05272974 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04012807 0,05270095 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,04012807 0,0526722 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04012807 0,05264348 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04012807 0,05261479 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04012807 0,05258614 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04012807 0,05255751 ! synaptogenesis GO:0007416 42 28 0,000 0,04012807 0,05252892 ! lipid oxidation GO:0034440 43 28 0,000 0,04012807 0,05250035 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04012807 0,05247182 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04012807 0,05244332 ! translational initiation GO:0006413 65 29 0,000 0,04153172 0,05424828 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,04153172 0,05421884 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04153172 0,05418944 ! regulation of pH GO:0006885 43 29 0,000 0,04153172 0,05416007 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04153172 0,05413073 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04153172 0,05410142 ! catechol metabolic process GO:0009712 54 29 0,000 0,04153172 0,05407215 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,04153172 0,0540429 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,04153172 0,05401369 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,04153172 0,05398451 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04153172 0,05395536 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,04153172 0,05392624 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04153172 0,05389715 ! cell fate determination GO:0001709 60 29 0,000 0,04153172 0,0538681 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04153172 0,05383908 ! detection of light stimulus GO:0009583 38 29 0,000 0,04153172 0,05381008 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,04153172 0,05378112 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,04153172 0,05375219 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,04153172 0,05372329 ! tissue homeostasis GO:0001894 48 29 0,000 0,04153172 0,05369443 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,04153172 0,05366559 ! phenol metabolic process GO:0018958 55 30 0,000 0,04293336 0,05544695 ! zinc ion transport GO:0006829 45 30 0,000 0,04293336 0,05541721 ! membrane docking GO:0022406 61 30 0,000 0,04293336 0,05538749 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04293336 0,05535781 ! cell junction assembly GO:0034329 78 30 0,000 0,04293336 0,05532816 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04293336 0,05529854 ! acute-phase response GO:0006953 49 30 0,000 0,04293336 0,05526895 ! myofibril assembly GO:0030239 47 30 0,000 0,04293336 0,0552394 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,04293336 0,05520987 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04293336 0,05518038 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04293336 0,05515092 ! phospholipid transport GO:0015914 51 30 0,000 0,04293336 0,05512149 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04293336 0,05509209 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04293336 0,05506273 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04293336 0,05503339 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04293336 0,05500409 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04293336 0,05497481 ! eye morphogenesis GO:0048592 60 30 0,000 0,04293336 0,05494557 ! regulation of B cell activation GO:0050864 50 30 0,000 0,04293336 0,05491636 ! response to heat GO:0009408 50 30 0,000 0,04293336 0,05488718 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,044333 0,05664642 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,044333 0,05661635 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,044333 0,05658632 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,044333 0,05655631 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,044333 0,05652634 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,044333 0,0564964 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,044333 0,05646649 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,044333 0,05643662 ! ovulation cycle process GO:0022602 49 31 0,000 0,044333 0,05640677 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,044333 0,05637696 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,044333 0,05634718 ! peptide transport GO:0015833 55 31 0,000 0,044333 0,05631743 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,044333 0,05628771 ! iron ion homeostasis GO:0055072 54 31 0,000 0,044333 0,05625802 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,044333 0,05622836 ! mesoderm formation GO:0001707 69 31 0,000 0,044333 0,05619874 ! natural killer cell activation GO:0030101 45 31 0,000 0,044333 0,05616915 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,044333 0,05613958 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,044333 0,05611005 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,044333 0,05608055 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,044333 0,05605108 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,044333 0,05602164 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04573064 0,05775744 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04573064 0,05772714 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04573064 0,05769687 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04573064 0,05766663 ! cholesterol transport GO:0030301 56 32 0,000 0,04573064 0,05763642 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04573064 0,05760624 ! spliceosome assembly GO:0000245 67 32 0,000 0,04573064 0,0575761 ! spindle organization GO:0007051 46 32 0,000 0,04573064 0,05754599 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04573064 0,0575159 ! metanephros development GO:0001656 74 32 0,000 0,04573064 0,05748585 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04573064 0,05745584 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04573064 0,05742585 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04573064 0,05739589 ! muscle cell development GO:0055001 49 32 0,000 0,04573064 0,05736597 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04573064 0,05733607 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04573064 0,05730621 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,04573064 0,05727638 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,04573064 0,05724658 ! ovulation cycle GO:0042698 51 32 0,000 0,04573064 0,05721681 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04573064 0,05718707 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04573064 0,05715736 ! hindbrain development GO:0030902 61 32 0,000 0,04573064 0,05712769 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04573064 0,05709804 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04573064 0,05706843 ! gene silencing GO:0016458 65 32 0,000 0,04573064 0,05703884 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04712628 0,05874914 ! post-embryonic development GO:0009791 69 33 0,000 0,04712628 0,05871871 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04712628 0,05868832 ! protein targeting to membrane GO:0006612 68 33 0,000 0,04712628 0,05865796 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04712628 0,05862763 ! ceramide metabolic process GO:0006672 64 33 0,000 0,04712628 0,05859733 ! formation of primary germ layer GO:0001704 72 33 0,000 0,04712628 0,05856706 ! cell fate specification GO:0001708 52 33 0,000 0,04712628 0,05853683 ! sterol transport GO:0015918 57 33 0,000 0,04712628 0,05850662 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04712628 0,05847645 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04712628 0,05844631 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04712628 0,0584162 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04712628 0,05838612 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04712628 0,05835607 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04851993 0,0600509 ! glial cell differentiation GO:0010001 63 34 0,000 0,04851993 0,06002002 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04851993 0,05998918 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04851993 0,05995837 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04851993 0,05992759 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04851993 0,05989684 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,04851993 0,05986613 ! mismatch repair GO:0006298 46 34 0,000 0,04851993 0,05983544 ! spermatid development GO:0007286 63 34 0,000 0,04851993 0,05980479 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04851993 0,05977417 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04851993 0,05974358 ! placenta development GO:0001890 53 34 0,000 0,04851993 0,05971302 ! regulation of muscle development GO:0048634 70 35 0,000 0,04991158 0,06139431 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04991158 0,06136294 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04991158 0,0613316 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04991158 0,06130029 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04991158 0,06126901 ! odontogenesis GO:0042476 66 35 0,000 0,04991158 0,06123777 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04991158 0,06120656 ! female gonad development GO:0008585 58 35 0,000 0,04991158 0,06117538 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04991158 0,06114423 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04991158 0,06111311 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,04991158 0,06108203 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04991158 0,06105097 ! cytokine production GO:0001816 59 35 0,000 0,04991158 0,06101995 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,04991158 0,06098896 ! neural tube formation GO:0001841 67 35 0,000 0,04991158 0,060958 ! vesicle localization GO:0051648 64 35 0,000 0,04991158 0,06092708 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,05130125 0,06259168 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,05130125 0,06255996 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,05130125 0,06252827 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,05130125 0,06249661 ! cell junction organization GO:0034330 86 36 0,000 0,05130125 0,06246498 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,05130125 0,06243338 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,05130125 0,06240182 ! positive regulation of cell development GO:0010720 80 36 0,000 0,05130125 0,06237029 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,05130125 0,06233879 ! regulation of proteolysis GO:0030162 72 36 0,000 0,05130125 0,06230732 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,05130125 0,06227588 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,05130125 0,06224448 ! aerobic respiration GO:0009060 55 36 0,000 0,05130125 0,06221311 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,05130125 0,06218176 ! embryonic organ development GO:0048568 57 36 0,000 0,05130125 0,06215045 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,05130125 0,06211917 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,05130125 0,06208793 ! RNA export from nucleus GO:0006405 56 37 0,000 0,05268893 0,06373532 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05268893 0,06370329 ! meiosis I GO:0007127 65 37 0,000 0,05268893 0,0636713 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,05268893 0,06363933 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05268893 0,0636074 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05268893 0,0635755 ! organic anion transport GO:0015711 68 37 0,000 0,05268893 0,06354364 ! tissue remodeling GO:0048771 76 37 0,000 0,05268893 0,0635118 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05268893 0,06348 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05268893 0,06344823 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05268893 0,06341649 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,05268893 0,06338478 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05268893 0,0633531 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05268893 0,06332146 ! glycogen metabolic process GO:0005977 61 37 0,000 0,05268893 0,06328984 ! pigment metabolic process GO:0042440 80 37 0,000 0,05268893 0,06325826 ! spermatid differentiation GO:0048515 66 37 0,000 0,05268893 0,06322671 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,05407462 0,0648572 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,05407462 0,06482488 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,05407462 0,0647926 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,05407462 0,06476035 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,05407462 0,06472813 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,05407462 0,06469594 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,05407462 0,06466378 ! lipid homeostasis GO:0055088 67 38 0,000 0,05407462 0,06463166 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,05407462 0,06459957 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,05407462 0,06456751 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,05407462 0,06453548 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,05407462 0,06450349 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,05407462 0,06447152 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,05407462 0,06443959 ! glucan metabolic process GO:0044042 62 38 0,000 0,05407462 0,06440769 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,05545833 0,06602313 ! mammary gland development GO:0030879 86 39 0,000 0,05545833 0,06599048 ! learning GO:0007612 77 39 0,000 0,05545833 0,06595786 ! ear morphogenesis GO:0042471 60 39 0,000 0,05545833 0,06592527 ! organic ether metabolic process GO:0018904 55 39 0,000 0,05545833 0,06589272 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05545833 0,06586019 ! segmentation GO:0035282 67 39 0,000 0,05545833 0,0658277 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05545833 0,06579524 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05545833 0,06576281 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05545833 0,06573042 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05545833 0,06569805 ! RNA modification GO:0009451 57 39 0,000 0,05545833 0,06566572 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05545833 0,06563342 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,05684007 0,0672356 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05684007 0,06720256 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05684007 0,06716955 ! feeding behavior GO:0007631 59 40 0,000 0,05684007 0,06713658 ! negative regulation of binding GO:0051100 72 40 0,000 0,05684007 0,06710363 ! mesenchymal cell development GO:0014031 87 40 0,000 0,05684007 0,06707072 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05684007 0,06703785 ! maintenance of protein location GO:0045185 91 40 0,000 0,05684007 0,067005 ! cytokinesis GO:0000910 72 40 0,000 0,05684007 0,06697219 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,05821983 0,06856432 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,05821983 0,06853078 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,05821983 0,06849726 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,05821983 0,06846379 ! gliogenesis GO:0042063 88 41 0,000 0,05821983 0,06843034 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,05821983 0,06839693 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,05821983 0,06836355 ! T cell differentiation GO:0030217 81 41 0,000 0,05821983 0,0683302 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,05821983 0,06829688 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,05821983 0,0682636 ! female gamete generation GO:0007292 61 41 0,000 0,05821983 0,06823035 ! polyol metabolic process GO:0019751 66 41 0,000 0,05821983 0,06819713 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,05821983 0,06816394 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,05959762 0,06974312 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,05959762 0,06970922 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,05959762 0,06967535 ! regulation of tube size GO:0035150 71 42 0,000 0,05959762 0,06964151 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,05959762 0,0696077 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,05959762 0,06957393 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,05959762 0,06954019 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,05959762 0,06950648 ! neuron migration GO:0001764 79 42 0,000 0,05959762 0,0694728 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,05959762 0,06943916 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,06097343 0,07100778 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,06097343 0,07097343 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,06097343 0,07093911 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,06097343 0,07090482 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,06097343 0,07087057 ! glucose transport GO:0015758 65 43 0,000 0,06097343 0,07083635 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,06097343 0,07080216 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,06097343 0,07076801 ! neural tube development GO:0021915 77 43 0,000 0,06097343 0,07073389 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,06097343 0,0706998 ! striated muscle contraction GO:0006941 77 43 0,000 0,06097343 0,07066574 ! phagocytosis GO:0006909 90 43 0,000 0,06097343 0,07063172 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,06097343 0,07059773 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,06234728 0,07215371 ! hexose transport GO:0008645 67 44 0,000 0,06234728 0,07211902 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,06234728 0,07208436 ! male sex differentiation GO:0046661 76 44 0,000 0,06234728 0,07204974 ! double-strand break repair GO:0006302 81 44 0,000 0,06234728 0,07201515 ! biopolymer methylation GO:0043414 84 44 0,000 0,06234728 0,0719806 ! B cell differentiation GO:0030183 107 44 0,000 0,06234728 0,07194607 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,06234728 0,07191158 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,06234728 0,07187713 ! developmental growth GO:0048589 82 44 0,000 0,06234728 0,0718427 ! maintenance of location in cell GO:0051651 97 44 0,000 0,06234728 0,07180831 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,06371917 0,07335326 ! glycolysis GO:0006096 65 45 0,000 0,06371917 0,07331818 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,06371917 0,07328314 ! leukocyte migration GO:0050900 68 45 0,000 0,06371917 0,07324812 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,06371917 0,07321314 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,06371917 0,0731782 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,06371917 0,07314328 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,06371917 0,0731084 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,06371917 0,07307356 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,06371917 0,07303874 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,06371917 0,07300396 ! cell growth GO:0016049 84 45 0,000 0,06371917 0,07296921 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,06508909 0,07450255 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,06508909 0,07446712 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,06508909 0,07443173 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,06508909 0,07439637 ! pigmentation GO:0043473 100 46 0,000 0,06508909 0,07436104 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06645706 0,07588784 ! response to calcium ion GO:0051592 81 47 0,000 0,06645706 0,07585184 ! endosome transport GO:0016197 108 47 0,000 0,06645706 0,07581588 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,06645706 0,07577994 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06645706 0,07574405 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06645706 0,07570818 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06645706 0,07567235 ! JNK cascade GO:0007254 91 47 0,000 0,06645706 0,07563656 ! methylation GO:0032259 90 47 0,000 0,06645706 0,07560079 ! Notch signaling pathway GO:0007219 96 48 0,000 0,06782307 0,07711829 ! cellular component disassembly GO:0022411 86 48 0,000 0,06782307 0,07708186 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,06782307 0,07704547 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,06782307 0,07700911 ! activation of caspase activity GO:0006919 84 48 0,000 0,06782307 0,07697278 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,06782307 0,07693649 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,06782307 0,07690023 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,06782307 0,07686401 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,06782307 0,07682782 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06918712 0,0783361 ! regulation of action potential GO:0001508 95 49 0,000 0,06918712 0,07829925 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,06918712 0,07826244 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,06918712 0,07822567 ! regulation of ion transport GO:0043269 77 49 0,000 0,06918712 0,07818892 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06918712 0,07815221 ! peptide metabolic process GO:0006518 76 49 0,000 0,06918712 0,07811554 ! response to temperature stimulus GO:0009266 76 49 0,000 0,06918712 0,0780789 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06918712 0,0780423 ! endocrine system development GO:0035270 104 49 0,000 0,06918712 0,07800572 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,06918712 0,07796919 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06918712 0,07793269 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06918712 0,07789622 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,06918712 0,07785978 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07054923 0,07935551 ! neuromuscular process GO:0050905 99 50 0,000 0,07054923 0,07931843 ! regulation of ossification GO:0030278 117 50 0,000 0,07054923 0,07928138 ! inner ear development GO:0048839 79 50 0,000 0,07054923 0,07924437 ! histone modification GO:0016570 91 50 0,000 0,07054923 0,07920739 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,07054923 0,07917045 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,07054923 0,07913354 ! positive regulation of binding GO:0051099 78 51 0,000 0,07190938 0,08062161 ! viral infectious cycle GO:0019058 99 51 0,000 0,07190938 0,08058406 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,07190938 0,08054654 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,07190938 0,08050906 ! excretion GO:0007588 83 51 0,000 0,07190938 0,08047162 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,07190938 0,08043421 ! chromatin remodeling GO:0006338 109 51 0,000 0,07190938 0,08039683 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,07190938 0,08035949 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,07190938 0,08032218 ! vesicle organization GO:0016050 107 51 0,000 0,07190938 0,08028491 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,07190938 0,08024767 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,07190938 0,08021047 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,07190938 0,0801733 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,0732676 0,08164976 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,0732676 0,08161196 ! membrane fusion GO:0006944 110 52 0,000 0,0732676 0,08157419 ! covalent chromatin modification GO:0016569 101 52 0,000 0,0732676 0,08153646 ! amino acid activation GO:0043038 92 52 0,000 0,0732676 0,08149877 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,0732676 0,08146111 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,07462386 0,08293072 ! RNA catabolic process GO:0006401 93 53 0,000 0,07462386 0,08289244 ! regulation of translational initiation GO:0006446 82 53 0,000 0,07462386 0,08285418 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,07462386 0,08281597 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,07462386 0,08277779 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,07462386 0,08273964 ! cell maturation GO:0048469 100 53 0,000 0,07462386 0,08270153 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,07462386 0,08266345 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,07462386 0,08262541 ! response to UV GO:0009411 104 53 0,000 0,07462386 0,0825874 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,07597819 0,0840476 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,07597819 0,08400898 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,07597819 0,08397039 ! cell recognition GO:0008037 85 54 0,000 0,07597819 0,08393183 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,07597819 0,08389331 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,07597819 0,08385483 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,07597819 0,08381638 ! chloride transport GO:0006821 90 55 0,000 0,07733059 0,0852692 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,07733059 0,08523014 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,07733059 0,08519111 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,07733059 0,08515212 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,07733059 0,08511317 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,07733059 0,08507425 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,07733059 0,08503537 ! aging GO:0007568 103 55 0,000 0,07733059 0,08499652 ! gastrulation GO:0007369 112 55 0,000 0,07733059 0,08495771 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,07733059 0,08491894 ! RNA elongation GO:0006354 79 55 0,000 0,07733059 0,0848802 ! nuclear export GO:0051168 97 55 0,000 0,07733059 0,08484149 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,07733059 0,08480282 ! regulation of actin filament length GO:0030832 105 56 0,000 0,07868104 0,08624446 ! sensory perception of smell GO:0007608 80 56 0,000 0,07868104 0,08620519 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,07868104 0,08616595 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,07868104 0,08612675 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,07868104 0,08608758 ! proton transport GO:0015992 94 56 0,000 0,07868104 0,08604845 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,08002957 0,08748348 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,08002957 0,08744375 ! muscle fiber development GO:0048747 112 57 0,000 0,08002957 0,08740406 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,08002957 0,0873644 ! maintenance of location GO:0051235 118 57 0,000 0,08002957 0,08732478 ! hydrogen transport GO:0006818 97 58 0,000 0,08137617 0,08875388 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,08137617 0,08871366 ! regulation of endocytosis GO:0030100 91 58 0,000 0,08137617 0,08867348 ! adult behavior GO:0030534 99 58 0,000 0,08137617 0,08863334 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,08137617 0,08859324 ! positive regulation of secretion GO:0051047 95 59 0,000 0,08272084 0,09001643 ! regulation of cellular component size GO:0032535 109 59 0,000 0,08272084 0,08997574 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,08272084 0,08993508 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,08272084 0,08989446 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,08272084 0,08985387 ! DNA catabolic process GO:0006308 86 59 0,000 0,08272084 0,08981333 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,08272084 0,08977282 ! establishment of organelle localization GO:0051656 109 59 0,000 0,08272084 0,08973234 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,08406358 0,09114781 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,08406358 0,09110675 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,08406358 0,09106573 ! regulation of heart contraction GO:0008016 110 60 0,000 0,08406358 0,09102474 ! camera-type eye development GO:0043010 116 60 0,000 0,08406358 0,0909838 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,08406358 0,09094289 ! kidney development GO:0001822 122 60 0,000 0,08406358 0,09090201 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,08540441 0,09231043 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,08540441 0,09226897 ! mesoderm development GO:0007498 119 61 0,000 0,08540441 0,09222756 ! tRNA processing GO:0008033 89 61 0,000 0,08540441 0,09218619 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,08540441 0,09214485 ! ear development GO:0043583 103 62 0,000 0,08674332 0,09354748 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,08674332 0,09350556 ! gonad development GO:0008406 98 62 0,000 0,08674332 0,09346369 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,08674332 0,09342185 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,08808031 0,09481934 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,08808031 0,09477693 ! detection of external stimulus GO:0009581 91 63 0,000 0,08808031 0,09473456 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,08808031 0,09469223 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,08808031 0,09464994 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,08941539 0,09604171 ! cell redox homeostasis GO:0045454 102 64 0,000 0,08941539 0,09599885 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,08941539 0,09595603 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,08941539 0,09591325 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,09074856 0,09729992 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,09074856 0,09725658 ! germ cell development GO:0007281 118 65 0,000 0,09074856 0,09721328 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,09074856 0,09717002 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,09207982 0,09855162 ! actin filament organization GO:0007015 148 66 0,000 0,09207982 0,0985078 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,09207982 0,09846402 ! extracellular matrix organization GO:0030198 133 66 0,000 0,09207982 0,09842028 ! secondary metabolic process GO:0019748 116 66 0,000 0,09207982 0,09837657 ! cell projection assembly GO:0030031 120 66 0,000 0,09207982 0,09833291 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,09340917 0,09970828 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,09340917 0,09966407 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,09340917 0,09961989 ! lung development GO:0030324 144 67 0,000 0,09340917 0,09957575 ! chromosome segregation GO:0007059 113 67 0,000 0,09340917 0,09953165 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,09340917 0,09948759 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,09340917 0,09944357 ! hexose catabolic process GO:0019320 104 67 0,000 0,09340917 0,09939959 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,09340917 0,09935565 ! adaptive immune response GO:0002250 119 67 0,000 0,09340917 0,09931174 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,09340917 0,09926788 ! amino acid transport GO:0006865 125 68 0,000 0,09473663 0,10063414 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,09473663 0,10058973 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,09473663 0,10054536 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,09473663 0,10050103 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,09473663 0,10045673 ! regulation of lipase activity GO:0060191 130 68 0,000 0,09473663 0,10041248 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,09473663 0,10036826 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,09473663 0,10032409 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,09606218 0,10168307 ! negative regulation of cell size GO:0045792 134 69 0,000 0,09606218 0,10163835 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,09606218 0,10159367 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,09606218 0,10154904 ! urogenital system development GO:0001655 137 69 0,000 0,09606218 0,10150444 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,09606218 0,10145988 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,09606218 0,10141536 ! antigen processing and presentation GO:0019882 104 69 0,000 0,09606218 0,10137088 ! respiratory tube development GO:0030323 150 70 0,000 0,09738584 0,10272264 ! amine catabolic process GO:0009310 117 71 0,000 0,0987076 0,10407121 ! reproductive structure development GO:0048608 113 71 0,000 0,0987076 0,10402562 ! humoral immune response GO:0006959 109 71 0,000 0,0987076 0,10398008 ! B cell activation GO:0042113 160 71 0,000 0,0987076 0,10393457 ! regulation of immune effector process GO:0002697 137 71 0,000 0,0987076 0,1038891 ! acute inflammatory response GO:0002526 113 72 0,000 0,10002747 0,10523223 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,10002747 0,10518623 ! carbohydrate transport GO:0008643 110 72 0,000 0,10002747 0,10514028 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,10002747 0,10509437 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,10002747 0,1050485 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,10002747 0,10500266 ! respiratory system development GO:0060541 153 72 0,000 0,10002747 0,10495687 ! learning or memory GO:0007611 147 73 0,000 0,10134546 0,10629345 ! regulation of blood pressure GO:0008217 125 73 0,000 0,10134546 0,10624713 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,10134546 0,10620086 ! axon guidance GO:0007411 139 73 0,000 0,10134546 0,10615462 ! fertilization GO:0009566 90 73 0,000 0,10134546 0,10610843 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,10266155 0,10743963 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,10266155 0,10739291 ! neurotransmitter transport GO:0006836 123 74 0,000 0,10266155 0,10734624 ! meiosis GO:0007126 121 74 0,000 0,10266155 0,10729961 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,10266155 0,10725302 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,10266155 0,10720647 ! eye development GO:0001654 143 74 0,000 0,10266155 0,10715996 ! organelle localization GO:0051640 136 74 0,000 0,10266155 0,10711349 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,10397577 0,10843767 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,10397577 0,10839068 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,10397577 0,10834374 ! meiotic cell cycle GO:0051321 122 75 0,000 0,10397577 0,10829684 ! rhythmic process GO:0048511 128 75 0,000 0,10397577 0,10824998 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,10397577 0,10820316 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1052881 0,10952147 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1052881 0,10947414 ! defense response to bacterium GO:0042742 89 76 0,000 0,1052881 0,10942685 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,1052881 0,1093796 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1052881 0,1093324 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,10659855 0,11064543 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,10659855 0,11059772 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,10659855 0,11055005 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,10659855 0,11050242 ! blood coagulation GO:0007596 146 78 0,000 0,10790713 0,11181075 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,10790713 0,11176261 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,10790713 0,11171452 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,10921383 0,1130187 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,10921383 0,11297011 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,10921383 0,11292157 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,10921383 0,11287306 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,11051867 0,11417257 ! response to metal ion GO:0010038 140 80 0,000 0,11051867 0,11412357 ! muscle cell differentiation GO:0042692 159 80 0,000 0,11051867 0,11407461 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,11051867 0,11402569 ! protein import into nucleus GO:0006606 158 80 0,000 0,11051867 0,11397682 ! inorganic anion transport GO:0015698 138 80 0,000 0,11051867 0,11392798 ! T cell activation GO:0042110 168 81 0,000 0,11182163 0,11522178 ! digestion GO:0007586 112 81 0,000 0,11182163 0,11517245 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,11182163 0,11512317 ! nuclear import GO:0051170 161 81 0,000 0,11182163 0,11507393 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,11182163 0,11502473 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,11312273 0,11631337 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,11312273 0,11626369 ! response to drug GO:0042493 143 82 0,000 0,11312273 0,11621405 ! response to nutrient GO:0007584 125 82 0,000 0,11312273 0,11616444 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,11312273 0,11611489 ! regulation of lyase activity GO:0051339 160 83 0,000 0,11442197 0,11739841 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,11571935 0,11867892 ! hemostasis GO:0007599 158 84 0,000 0,11571935 0,11862836 ! negative regulation of growth GO:0045926 155 84 0,000 0,11571935 0,11857783 ! regulation of ligase activity GO:0051340 142 84 0,000 0,11571935 0,11852735 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,11571935 0,11847691 ! nucleosome assembly GO:0006334 122 85 0,000 0,11701487 0,11975235 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,11701487 0,11970143 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,11701487 0,11965056 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,11830853 0,12092197 ! response to inorganic substance GO:0010035 153 86 0,000 0,11830853 0,12087063 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,11830853 0,12081932 ! chromatin assembly GO:0031497 124 86 0,000 0,11830853 0,12076806 ! alcohol catabolic process GO:0046164 130 86 0,000 0,11830853 0,12071685 ! amine transport GO:0015837 155 86 0,000 0,11830853 0,12066568 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,11960034 0,12193154 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,11960034 0,12187989 ! protein localization in nucleus GO:0034504 176 87 0,000 0,11960034 0,12182829 ! cellular respiration GO:0045333 135 88 0,000 0,12089031 0,12309017 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,12089031 0,12303811 ! regulation of DNA binding GO:0051101 155 88 0,000 0,12089031 0,12298608 ! gland development GO:0048732 206 88 0,000 0,12089031 0,1229341 ! regulation of neurological system process GO:0031644 148 88 0,000 0,12089031 0,12288216 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,12089031 0,12283027 ! cellular defense response GO:0006968 114 89 0,000 0,12217842 0,12408666 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,12217842 0,1240343 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,12217842 0,12398199 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,12346469 0,12523442 ! sex differentiation GO:0007548 145 90 0,000 0,12346469 0,12518165 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,12346469 0,12512892 ! sterol metabolic process GO:0016125 152 91 0,000 0,12474912 0,12637743 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,12474912 0,12632424 ! regulation of defense response GO:0031347 149 92 0,000 0,12603171 0,12756933 ! nucleosome organization GO:0034728 138 92 0,000 0,12603171 0,12751569 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,12603171 0,12746209 ! vitamin metabolic process GO:0006766 139 92 0,000 0,12603171 0,12740853 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,12731247 0,12864922 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,12731247 0,12859521 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,12731247 0,12854125 ! regulation of membrane potential GO:0042391 164 93 0,000 0,12731247 0,12848733 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,12731247 0,12843346 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,12859138 0,12966927 ! transcription initiation GO:0006352 153 94 0,000 0,12859138 0,12961494 ! regulation of T cell activation GO:0050863 158 94 0,000 0,12859138 0,12956067 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,12986847 0,13079261 ! forebrain development GO:0030900 188 95 0,000 0,12986847 0,13073788 ! leukocyte differentiation GO:0002521 202 96 0,000 0,13114373 0,13196646 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,13114373 0,13191129 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,13114373 0,13185617 ! positive regulation of immune response GO:0050778 156 96 0,000 0,13114373 0,13180109 ! detection of stimulus GO:0051606 151 96 0,000 0,13114373 0,13174606 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,13241716 0,13296982 ! protein ubiquitination GO:0016567 217 97 0,000 0,13241716 0,13291435 ! hormone metabolic process GO:0042445 157 97 0,000 0,13241716 0,13285892 ! response to virus GO:0009615 160 98 0,000 0,13368877 0,13407886 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,13368877 0,13402299 ! interphase GO:0051325 213 98 0,000 0,13368877 0,13396717 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,13368877 0,1339114 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,13495855 0,13512704 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,13495855 0,13507083 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,13495855 0,13501467 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,13622652 0,13622652