pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/798-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! insulin receptor signaling pathway GO:0008286 66 27 3,000 6,97E-08 1,703E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,645E-07 2,01E-04 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 2,897E-07 2,359E-04 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 3,518E-07 2,149E-04 ! branching morphogenesis of a tube GO:0048754 102 45 3,000 5,803E-07 2,836E-04 ! response to insulin stimulus GO:0032868 98 47 3,000 6,932E-07 2,823E-04 ! morphogenesis of a branching structure GO:0001763 116 52 3,000 1,047E-06 3,652E-04 ! patterning of blood vessels GO:0001569 43 18 2,000 2,373E-06 7,245E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 2,373E-06 6,44E-04 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 2,425E-06 5,923E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 3,855E-06 8,562E-04 ! collagen catabolic process GO:0030574 29 21 2,000 3,855E-06 7,849E-04 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 7,553E-06 1,419E-03 ! multicellular organismal catabolic process GO:0044243 38 27 2,000 8,426E-06 1,47E-03 ! tube morphogenesis GO:0035239 194 89 3,000 9,069E-06 1,477E-03 ! collagen metabolic process GO:0032963 49 32 2,000 1,421E-05 2,17E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 2,000 1,87E-05 2,687E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,093E-05 2,841E-03 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 3,027E-05 3,892E-03 ! protein refolding GO:0042026 15 6 1,000 3,137E-05 3,832E-03 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 4,288E-05 4,988E-03 ! regulation of granule cell precursor proliferation GO:0021936 12 7 1,000 4,388E-05 4,872E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! male sex determination GO:0030238 15 7 1,000 4,388E-05 4,66E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 5,845E-05 5,949E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 5,845E-05 5,712E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 5,845E-05 5,492E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 5,845E-05 5,288E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 7,508E-05 6,55E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 7,508E-05 6,325E-03 GO:0010469|regulation of receptor activity, ! regulation of glycolysis GO:0006110 20 9 1,000 7,508E-05 6,114E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 7,508E-05 5,917E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 9,376E-05 7,158E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 9,376E-05 6,941E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 9,376E-05 6,737E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 9,376E-05 6,544E-03 GO:0043470|regulation of carbohydrate catabolic process, ! natural killer cell mediated immunity GO:0002228 19 10 1,000 9,376E-05 6,362E-03 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of embryonic development GO:0045995 35 11 1,000 1,145E-04 7,559E-03 ! activation of MAPK activity GO:0000187 124 67 2,000 1,324E-04 8,513E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,373E-04 8,598E-03 ! virus-host interaction GO:0019048 30 12 1,000 1,373E-04 8,383E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,373E-04 8,178E-03 ! leukocyte mediated cytotoxicity GO:0001909 28 12 1,000 1,373E-04 7,984E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,621E-04 9,207E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! bone mineralization GO:0030282 18 14 1,000 1,889E-04 0,01048764 ! protein oligomerization GO:0051259 149 79 2,000 2,159E-04 0,01172106 ! cell killing GO:0001906 32 15 1,000 2,177E-04 0,01156415 ! response to hypoxia GO:0001666 178 81 2,000 2,325E-04 0,01208303 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,486E-04 0,01265363 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 2,486E-04 0,0123954 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 2,486E-04 0,01214749 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,486E-04 0,0119093 ! biomineral formation GO:0031214 22 16 1,000 2,486E-04 0,01168028 ! response to oxygen levels GO:0070482 183 83 2,000 2,498E-04 0,01151536 ! activation of MAPKK activity GO:0000186 43 17 1,000 2,815E-04 0,01273542 ! regulation of protein transport GO:0051223 165 87 2,000 2,87E-04 0,01274853 GO:0070201|regulation of establishment of protein localization, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 3,164E-04 0,01380272 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 3,492E-04 0,01496714 ! female pregnancy GO:0007565 166 94 2,000 3,604E-04 0,01517835 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,922E-04 0,01623863 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,922E-04 0,01596798 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 3,922E-04 0,01570621 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of protein localization GO:0032880 188 97 2,000 3,951E-04 0,01556994 ! lipid phosphorylation GO:0046834 43 21 1,000 4,33E-04 0,01679266 ! hindlimb morphogenesis GO:0035137 47 22 1,000 4,759E-04 0,01816629 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 4,759E-04 0,0178868 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,207E-04 0,01927543 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 5,676E-04 0,0206945 ! sex determination GO:0007530 48 24 1,000 5,676E-04 0,02039017 ! interaction with host GO:0051701 66 25 1,000 6,163E-04 0,02182158 ! protein tetramerization GO:0051262 57 25 1,000 6,163E-04 0,02150985 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 6,671E-04 0,02295263 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 6,671E-04 0,02263385 ! positive regulation of nuclear division GO:0051785 41 26 1,000 6,671E-04 0,02232379 GO:0045840|positive regulation of mitosis, ! mitochondrial membrane organization GO:0007006 60 27 1,000 7,198E-04 0,02376164 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 7,744E-04 0,02522464 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 7,744E-04 0,02489274 ! response to mechanical stimulus GO:0009612 60 32 1,000 1,012E-03 0,03211883 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,012E-03 0,03170705 ! positive regulation of catabolic process GO:0009896 72 32 1,000 1,012E-03 0,0313057 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 1,143E-03 0,03490029 ! negative regulation of secretion GO:0051048 68 35 1,000 1,211E-03 0,0365243 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 1,427E-03 0,04250823 ! carbohydrate homeostasis GO:0033500 59 39 1,000 1,503E-03 0,04422477 GO:0042593|glucose homeostasis, ! regulation of intracellular protein transport GO:0033157 86 42 1,000 1,741E-03 0,05063273 ! regulation of protein secretion GO:0050708 77 42 1,000 1,741E-03 0,05003705 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 2,085E-03 0,05922784 ! positive regulation of protein transport GO:0051222 80 46 1,000 2,085E-03 0,05854706 ! regulation of JNK cascade GO:0046328 104 47 1,000 2,176E-03 0,06039782 ! positive regulation of cell cycle GO:0045787 96 48 1,000 2,268E-03 0,06225749 ! mitochondrial transport GO:0006839 94 48 1,000 2,268E-03 0,06156574 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 2,268E-03 0,0608892 ! protein homooligomerization GO:0051260 84 49 1,000 2,362E-03 0,0627316 ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 2,459E-03 0,06458243 ! response to estrogen stimulus GO:0043627 98 52 1,000 2,656E-03 0,06903443 ! positive regulation of growth GO:0045927 96 53 1,000 2,758E-03 0,07092023 ! cartilage development GO:0051216 99 53 1,000 2,758E-03 0,07018148 ! regulation of DNA replication GO:0006275 105 56 1,000 3,073E-03 0,07740646 ! heart morphogenesis GO:0003007 105 57 1,000 3,182E-03 0,07932858 ! regulation of intracellular transport GO:0032386 108 57 1,000 3,182E-03 0,07852728 ! positive regulation of cell migration GO:0030335 137 58 1,000 3,293E-03 0,0804434 ! positive regulation of organelle organization GO:0010638 108 58 1,000 3,293E-03 0,07964693 ! lipid modification GO:0030258 112 60 1,000 3,519E-03 0,08429079 ! viral reproductive process GO:0022415 132 62 1,000 3,753E-03 0,08901249 ! regulation of mitosis GO:0007088 112 63 1,000 3,872E-03 0,09096209 GO:0051783|regulation of nuclear division, ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 3,993E-03 0,0929154 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 4,116E-03 0,09487218 ! positive regulation of cell motion GO:0051272 157 65 1,000 4,116E-03 0,09398553 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 4,368E-03 0,09879534 GO:0035113|embryonic appendage morphogenesis, ! regulation of cellular response to stress GO:0080135 142 68 1,000 4,496E-03 0,1007613 ! viral reproduction GO:0016032 142 68 1,000 4,496E-03 0,09984529 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 4,626E-03 0,10180444 ! developmental maturation GO:0021700 128 69 1,000 4,626E-03 0,10089547 ! appendage morphogenesis GO:0035107 150 72 1,000 5,026E-03 0,10864999 GO:0035108|limb morphogenesis, ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 5,026E-03 0,10769692 ! appendage development GO:0048736 151 73 1,000 5,162E-03 0,10966551 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 5,301E-03 0,11163605 ! leukocyte mediated immunity GO:0002443 136 75 1,000 5,441E-03 0,11360838 ! cell-matrix adhesion GO:0007160 181 76 1,000 5,583E-03 0,11558234 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 5,726E-03 0,1175578 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 5,726E-03 0,11657815 ! regulation of catabolic process GO:0009894 173 77 1,000 5,726E-03 0,1156147 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 6,018E-03 0,12051663 ! activation of protein kinase activity GO:0032147 170 80 1,000 6,167E-03 0,12248774 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 6,317E-03 0,12445994 ! regulation of peptidase activity GO:0052547 150 82 1,000 6,469E-03 0,12643309 ! cell-substrate adhesion GO:0031589 189 82 1,000 6,469E-03 0,12542966 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 6,623E-03 0,12739601 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 164 85 1,000 6,935E-03 0,13235712 ! mitochondrion organization GO:0007005 159 87 1,000 7,253E-03 0,13736583 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 7,294E-03 0,13706949 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 7,294E-03 0,13602316 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 7,294E-03 0,13499268 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,294E-03 0,1339777 ! positive regulation of helicase activity GO:0051096 12 5 0,000 7,294E-03 0,13297787 ! neuron fate determination GO:0048664 7 5 0,000 7,294E-03 0,13199284 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,294E-03 0,13102231 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 7,294E-03 0,13006594 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 7,294E-03 0,12912344 ! polyol transport GO:0015791 12 5 0,000 7,294E-03 0,12819449 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,294E-03 0,12727881 ! response to superoxide GO:0000303 10 5 0,000 7,294E-03 0,12637613 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,294E-03 0,12548616 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 7,294E-03 0,12460863 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 7,294E-03 0,12374329 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,294E-03 0,12288989 ! female meiosis GO:0007143 10 5 0,000 7,294E-03 0,12204818 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 7,294E-03 0,12121792 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,294E-03 0,12039888 ! hypothalamus development GO:0021854 9 5 0,000 7,294E-03 0,11959083 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 7,294E-03 0,11879356 ! cobalt ion transport GO:0006824 11 5 0,000 7,294E-03 0,11800685 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 7,294E-03 0,11723049 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 7,294E-03 0,11646427 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,294E-03 0,11570801 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,294E-03 0,11496151 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 7,294E-03 0,11422458 ! embryonic camera-type eye development GO:0031076 12 5 0,000 7,294E-03 0,11349703 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,294E-03 0,1127787 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,294E-03 0,1120694 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 7,294E-03 0,11136896 ! transposition GO:0032196 9 5 0,000 7,294E-03 0,11067723 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 7,294E-03 0,10999404 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 7,294E-03 0,10931923 ! negative chemotaxis GO:0050919 16 5 0,000 7,294E-03 0,10865265 ! positive regulation of histone modification GO:0031058 6 5 0,000 7,294E-03 0,10799415 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,294E-03 0,10734358 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 7,294E-03 0,1067008 ! behavioral response to pain GO:0048266 10 5 0,000 7,294E-03 0,10606568 ! clathrin coat assembly GO:0048268 15 5 0,000 7,294E-03 0,10543807 ! Notch receptor processing GO:0007220 11 5 0,000 7,294E-03 0,10481785 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,294E-03 0,10420488 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 7,294E-03 0,10359904 ! micturition GO:0060073 9 5 0,000 7,294E-03 0,1030002 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,294E-03 0,10240824 ! copulation GO:0007620 9 5 0,000 7,294E-03 0,10182305 ! glial cell fate commitment GO:0021781 14 5 0,000 7,294E-03 0,10124451 ! protein maturation by protein folding GO:0022417 14 5 0,000 7,294E-03 0,10067251 ! bioluminescence GO:0008218 9 5 0,000 7,294E-03 0,10010693 ! spermidine metabolic process GO:0008216 7 5 0,000 7,294E-03 0,09954768 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,294E-03 0,09899463 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,294E-03 0,0984477 ! apoptotic cell clearance GO:0043277 23 5 0,000 7,294E-03 0,09790678 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,294E-03 0,09737177 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 7,294E-03 0,09684258 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,294E-03 0,0963191 ! grooming behavior GO:0007625 6 5 0,000 7,294E-03 0,09580126 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 7,294E-03 0,09528895 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,294E-03 0,0947821 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 7,294E-03 0,0942806 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,294E-03 0,09378439 ! response to protozoan GO:0001562 13 5 0,000 7,294E-03 0,09329337 ! lymph vessel development GO:0001945 10 5 0,000 7,294E-03 0,09280747 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 7,294E-03 0,0923266 ! endochondral ossification GO:0001958 17 5 0,000 7,294E-03 0,09185069 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,294E-03 0,09137966 ! single strand break repair GO:0000012 8 5 0,000 7,294E-03 0,09091344 ! parathyroid gland development GO:0060017 14 5 0,000 7,294E-03 0,09045195 ! anagen GO:0042640 7 5 0,000 7,294E-03 0,08999512 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,294E-03 0,08954288 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,294E-03 0,08909517 ! cytokine secretion GO:0050663 15 5 0,000 7,294E-03 0,08865191 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 7,294E-03 0,08821304 ! ceramide catabolic process GO:0046514 7 5 0,000 7,294E-03 0,08777849 ! skeletal myofibril assembly GO:0014866 12 5 0,000 7,294E-03 0,08734821 ! smooth muscle tissue development GO:0048745 32 5 0,000 7,294E-03 0,08692212 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,294E-03 0,08650017 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,294E-03 0,08608229 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,294E-03 0,08566843 ! cardiac muscle fiber development GO:0048739 12 5 0,000 7,294E-03 0,08525854 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,294E-03 0,08485254 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 7,294E-03 0,0844504 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,294E-03 0,08405205 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 7,294E-03 0,08365744 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,294E-03 0,08326651 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 7,294E-03 0,08287923 ! glycine biosynthetic process GO:0006545 7 5 0,000 7,294E-03 0,08249553 ! microvillus organization GO:0032528 8 5 0,000 7,294E-03 0,08211536 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 7,294E-03 0,08173869 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 7,294E-03 0,08136545 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 7,294E-03 0,08099561 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 7,294E-03 0,08062911 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 7,294E-03 0,08026592 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 7,294E-03 0,07990598 ! polyol catabolic process GO:0046174 9 5 0,000 7,294E-03 0,07954926 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 7,294E-03 0,07919571 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 7,294E-03 0,07884528 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 7,294E-03 0,07849795 ! muscle cell migration GO:0014812 8 5 0,000 7,294E-03 0,07815366 ! mitochondrial fission GO:0000266 8 5 0,000 7,294E-03 0,07781238 ! sister chromatid cohesion GO:0007062 15 5 0,000 7,294E-03 0,07747406 ! response to tumor necrosis factor GO:0034612 10 5 0,000 7,294E-03 0,07713868 ! mRNA transcription GO:0009299 10 5 0,000 7,294E-03 0,07680618 ! nerve growth factor processing GO:0032455 9 5 0,000 7,294E-03 0,07647654 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 7,294E-03 0,07614972 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 7,294E-03 0,07582568 ! anaerobic glycolysis GO:0019642 6 5 0,000 7,294E-03 0,07550438 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,294E-03 0,0751858 ! monocyte activation GO:0042117 10 5 0,000 7,294E-03 0,07486989 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,294E-03 0,07455663 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,294E-03 0,07424598 ! response to food GO:0032094 6 5 0,000 7,294E-03 0,0739379 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,294E-03 0,07363237 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,294E-03 0,07332936 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 7,294E-03 0,07302883 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,294E-03 0,07273075 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 7,294E-03 0,0724351 ! forebrain neuron development GO:0021884 13 5 0,000 7,294E-03 0,07214184 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,294E-03 0,07185094 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 7,294E-03 0,07156239 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 7,294E-03 0,07127614 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,294E-03 0,07099217 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,294E-03 0,07071045 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 7,294E-03 0,07043096 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,294E-03 0,07015368 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 7,294E-03 0,06987856 ! lipid glycosylation GO:0030259 7 5 0,000 7,294E-03 0,0696056 ! nucleobase transport GO:0015851 6 5 0,000 7,294E-03 0,06933476 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,294E-03 0,06906602 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 7,294E-03 0,06879936 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 7,294E-03 0,06853475 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 7,294E-03 0,06827216 ! basic amino acid transport GO:0015802 12 5 0,000 7,294E-03 0,06801158 ! cellular glucose homeostasis GO:0001678 6 5 0,000 7,294E-03 0,06775298 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 7,294E-03 0,06749634 ! actin nucleation GO:0045010 11 5 0,000 7,294E-03 0,06724164 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,294E-03 0,06698885 ! depurination GO:0045007 5 5 0,000 7,294E-03 0,06673796 ! depyrimidination GO:0045008 10 5 0,000 7,294E-03 0,06648893 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,294E-03 0,06624176 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,294E-03 0,06599642 ! G2/M transition checkpoint GO:0031576 8 5 0,000 7,294E-03 0,06575289 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,294E-03 0,06551115 ! zinc ion homeostasis GO:0055069 9 5 0,000 7,294E-03 0,06527119 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 7,294E-03 0,06503297 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 7,294E-03 0,06479649 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,294E-03 0,06456172 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,294E-03 0,06432864 ! activated T cell proliferation GO:0050798 16 5 0,000 7,294E-03 0,06409724 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,294E-03 0,06386751 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 7,294E-03 0,06363941 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,294E-03 0,06341293 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,294E-03 0,06318806 ! gamma-delta T cell activation GO:0046629 6 5 0,000 7,294E-03 0,06296478 ! response to arsenic GO:0046685 11 5 0,000 7,294E-03 0,06274308 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 7,294E-03 0,06252293 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,294E-03 0,06230431 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 7,294E-03 0,06208723 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 7,294E-03 0,06187165 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 7,294E-03 0,06165756 ! response to mercury ion GO:0046689 8 5 0,000 7,294E-03 0,06144494 ! response to cadmium ion GO:0046686 7 5 0,000 7,294E-03 0,06123379 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 7,294E-03 0,06102409 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 7,294E-03 0,06081582 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 7,294E-03 0,06060896 ! bile acid biosynthetic process GO:0006699 7 5 0,000 7,294E-03 0,06040351 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,294E-03 0,06019944 ! ganglioside catabolic process GO:0006689 12 5 0,000 7,294E-03 0,05999675 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,294E-03 0,05979542 ! decidualization GO:0046697 11 5 0,000 7,294E-03 0,05959543 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 7,294E-03 0,05939678 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 7,294E-03 0,05919945 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 7,294E-03 0,05900342 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 7,294E-03 0,05880869 ! embryonic cleavage GO:0040016 6 5 0,000 7,294E-03 0,05861524 ! peroxisome fission GO:0016559 5 5 0,000 7,294E-03 0,05842306 ! histone demethylation GO:0016577 13 5 0,000 7,294E-03 0,05823214 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 7,294E-03 0,05804246 ! mitotic recombination GO:0006312 9 5 0,000 7,294E-03 0,05785401 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 7,294E-03 0,05766678 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,294E-03 0,05748075 ! metaphase plate congression GO:0051310 7 5 0,000 7,294E-03 0,05729593 ! regulation of sterol transport GO:0032371 7 5 0,000 7,294E-03 0,05711229 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,294E-03 0,05692982 ! enteric nervous system development GO:0048484 8 5 0,000 7,294E-03 0,05674852 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 7,294E-03 0,05656836 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 7,294E-03 0,05638935 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 7,294E-03 0,05621146 ! muscle cell proliferation GO:0033002 12 5 0,000 7,294E-03 0,0560347 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,294E-03 0,05585904 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 7,294E-03 0,05568448 ! B cell homeostasis GO:0001782 13 5 0,000 7,294E-03 0,05551101 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 7,294E-03 0,05533862 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,294E-03 0,05516729 ! metaphase GO:0051323 11 5 0,000 7,294E-03 0,05499702 ! melatonin biosynthetic process GO:0030187 7 5 0,000 7,294E-03 0,0548278 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 7,294E-03 0,05465961 ! cellular response to nutrient GO:0031670 8 5 0,000 7,294E-03 0,05449246 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,294E-03 0,05432632 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 7,294E-03 0,0541612 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 7,294E-03 0,05399707 ! regulation of hair follicle development GO:0051797 10 5 0,000 7,294E-03 0,05383394 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 7,294E-03 0,05367179 ! response to redox state GO:0051775 6 5 0,000 7,294E-03 0,05351061 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 7,294E-03 0,0533504 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 7,294E-03 0,05319115 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,294E-03 0,05303284 ! brown fat cell differentiation GO:0050873 7 5 0,000 7,294E-03 0,05287547 ! regulation of telomerase activity GO:0051972 7 5 0,000 7,294E-03 0,05271904 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,294E-03 0,05256352 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 7,294E-03 0,05240892 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,294E-03 0,05225523 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 7,294E-03 0,05210244 ! striatum development GO:0021756 14 5 0,000 7,294E-03 0,05195054 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 7,294E-03 0,05179952 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,294E-03 0,05164937 ! glial cell migration GO:0008347 10 5 0,000 7,294E-03 0,0515001 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,294E-03 0,05135168 ! neural plate morphogenesis GO:0001839 7 5 0,000 7,294E-03 0,05120412 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 7,294E-03 0,0510574 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,294E-03 0,05091153 ! T cell activation during immune response GO:0002286 9 5 0,000 7,294E-03 0,05076648 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,294E-03 0,05062226 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,294E-03 0,05047885 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 7,294E-03 0,05033625 ! neuroprotection GO:0043526 8 5 0,000 7,294E-03 0,05019446 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,294E-03 0,05005347 ! regulation of sensory perception GO:0051931 8 5 0,000 7,294E-03 0,04991326 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,294E-03 0,04977384 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,294E-03 0,04963519 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 7,294E-03 0,04949732 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 7,294E-03 0,04936021 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,294E-03 0,04922385 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 7,294E-03 0,04908825 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,294E-03 0,04895339 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 7,294E-03 0,04881927 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 7,294E-03 0,04868589 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 7,294E-03 0,04855323 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,294E-03 0,04842129 ! spindle assembly GO:0051225 6 5 0,000 7,294E-03 0,04829007 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,294E-03 0,04815955 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,294E-03 0,04802974 ! protein palmitoylation GO:0018345 12 5 0,000 7,294E-03 0,04790063 ! drug metabolic process GO:0017144 7 5 0,000 7,294E-03 0,04777221 ! stem cell division GO:0017145 11 5 0,000 7,294E-03 0,04764448 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,294E-03 0,04751742 ! organ regeneration GO:0031100 7 5 0,000 7,294E-03 0,04739105 ! carnitine metabolic process GO:0009437 8 5 0,000 7,294E-03 0,04726534 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,294E-03 0,0471403 ! response to unfolded protein GO:0006986 139 90 1,000 7,744E-03 0,04991509 ! regulation of cell cycle process GO:0010564 161 90 1,000 7,744E-03 0,04978373 ! ossification GO:0001503 205 91 1,000 7,91E-03 0,05072166 ! bone development GO:0060348 206 92 1,000 8,079E-03 0,051665 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,746E-03 0,05578985 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,746E-03 0,05564457 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 8,746E-03 0,05550003 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 8,746E-03 0,05535625 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,746E-03 0,05521321 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 8,746E-03 0,05507091 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 8,746E-03 0,05492934 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,746E-03 0,0547885 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 8,746E-03 0,05464837 ! response to oxygen radical GO:0000305 11 6 0,000 8,746E-03 0,05450896 ! positive regulation of axon extension GO:0045773 13 6 0,000 8,746E-03 0,05437026 ! myoblast cell fate commitment GO:0048625 18 6 0,000 8,746E-03 0,05423227 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 8,746E-03 0,05409497 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 8,746E-03 0,05395837 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,746E-03 0,05382245 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,746E-03 0,05368722 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 8,746E-03 0,05355267 ! forebrain regionalization GO:0021871 9 6 0,000 8,746E-03 0,05341878 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,746E-03 0,05328557 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,746E-03 0,05315302 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 8,746E-03 0,05302113 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,746E-03 0,05288988 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 8,746E-03 0,05275929 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 8,746E-03 0,05262934 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,746E-03 0,05250003 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 8,746E-03 0,05237136 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 8,746E-03 0,05224331 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,746E-03 0,05211589 ! malate metabolic process GO:0006108 13 6 0,000 8,746E-03 0,05198908 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 8,746E-03 0,0518629 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 8,746E-03 0,05173732 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 8,746E-03 0,05161235 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 8,746E-03 0,05148798 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,746E-03 0,05136422 ! opsonization GO:0008228 8 6 0,000 8,746E-03 0,05124104 ! mating behavior GO:0007617 7 6 0,000 8,746E-03 0,05111845 ! erythrocyte maturation GO:0043249 8 6 0,000 8,746E-03 0,05099645 ! embryonic hemopoiesis GO:0035162 16 6 0,000 8,746E-03 0,05087503 ! protein amino acid dealkylation GO:0008214 15 6 0,000 8,746E-03 0,05075419 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 8,746E-03 0,05063392 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 8,746E-03 0,05051422 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,746E-03 0,05039508 ! response to interferon-gamma GO:0034341 16 6 0,000 8,746E-03 0,0502765 ! toxin metabolic process GO:0009404 11 6 0,000 8,746E-03 0,05015848 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,746E-03 0,05004102 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 8,746E-03 0,0499241 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 8,746E-03 0,04980772 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 8,746E-03 0,04969189 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 8,746E-03 0,0495766 ! cGMP-mediated signaling GO:0019934 14 6 0,000 8,746E-03 0,04946184 ! dorsal spinal cord development GO:0021516 10 6 0,000 8,746E-03 0,04934761 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,746E-03 0,0492339 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 8,746E-03 0,04912072 ! thymic T cell selection GO:0045061 16 6 0,000 8,746E-03 0,04900806 ! sphingoid catabolic process GO:0046521 8 6 0,000 8,746E-03 0,04889591 ! protein lipoylation GO:0009249 10 6 0,000 8,746E-03 0,04878428 ! transepithelial chloride transport GO:0030321 12 6 0,000 8,746E-03 0,04867315 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 8,746E-03 0,04856253 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,746E-03 0,04845241 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 8,746E-03 0,04834279 ! glutamate catabolic process GO:0006538 12 6 0,000 8,746E-03 0,04823366 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 8,746E-03 0,04812503 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 8,746E-03 0,04801688 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 8,746E-03 0,04790922 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,746E-03 0,04780204 ! hyperosmotic response GO:0006972 10 6 0,000 8,746E-03 0,04769534 ! L-serine biosynthetic process GO:0006564 7 6 0,000 8,746E-03 0,04758912 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 8,746E-03 0,04748336 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 8,746E-03 0,04737808 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,746E-03 0,04727326 ! urea metabolic process GO:0019627 7 6 0,000 8,746E-03 0,0471689 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,746E-03 0,04706501 ! neutrophil activation GO:0042119 7 6 0,000 8,746E-03 0,04696157 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,746E-03 0,04685858 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 8,746E-03 0,04675605 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,746E-03 0,04665396 ! paraxial mesoderm development GO:0048339 16 6 0,000 8,746E-03 0,04655232 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 8,746E-03 0,04645112 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,746E-03 0,04635035 ! neuron apoptosis GO:0051402 15 6 0,000 8,746E-03 0,04625003 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,746E-03 0,04615014 ! T cell mediated immunity GO:0002456 17 6 0,000 8,746E-03 0,04605068 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,746E-03 0,04595164 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 8,746E-03 0,04585303 ! carnitine transport GO:0015879 10 6 0,000 8,746E-03 0,04575485 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,746E-03 0,04565708 ! positive regulation of exocytosis GO:0045921 11 6 0,000 8,746E-03 0,04555973 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 8,746E-03 0,04546279 ! early endosome to late endosome transport GO:0045022 16 6 0,000 8,746E-03 0,04536627 ! 5S class rRNA transcription GO:0042791 13 6 0,000 8,746E-03 0,04527016 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,746E-03 0,04517445 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 8,746E-03 0,04507914 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 8,746E-03 0,04498424 ! sodium ion homeostasis GO:0055078 12 6 0,000 8,746E-03 0,04488973 ! establishment of spindle localization GO:0051293 16 6 0,000 8,746E-03 0,04479563 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 8,746E-03 0,04470191 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,746E-03 0,04460859 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 8,746E-03 0,04451565 ! response to UV-C GO:0010225 14 6 0,000 8,746E-03 0,0444231 ! astrocyte development GO:0014002 16 6 0,000 8,746E-03 0,04433094 ! protein targeting to lysosome GO:0006622 12 6 0,000 8,746E-03 0,04423916 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,746E-03 0,04414776 ! interaction with symbiont GO:0051702 14 6 0,000 8,746E-03 0,04405673 ! regulation of dendrite development GO:0050773 16 6 0,000 8,746E-03 0,04396608 ! peptidyl-arginine modification GO:0018195 13 6 0,000 8,746E-03 0,0438758 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 8,746E-03 0,04378589 ! response to copper ion GO:0046688 10 6 0,000 8,746E-03 0,04369635 ! response to exogenous dsRNA GO:0043330 13 6 0,000 8,746E-03 0,04360717 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 8,746E-03 0,04351836 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,746E-03 0,04342991 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 8,746E-03 0,04334181 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,746E-03 0,04325408 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 8,746E-03 0,04316669 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,746E-03 0,04307966 ! nucleoside catabolic process GO:0009164 10 6 0,000 8,746E-03 0,04299298 ! hair follicle maturation GO:0048820 8 6 0,000 8,746E-03 0,04290665 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,746E-03 0,04282067 ! Schwann cell development GO:0014044 15 6 0,000 8,746E-03 0,04273503 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 8,746E-03 0,04264973 ! response to pheromone GO:0019236 6 6 0,000 8,746E-03 0,04256477 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 8,746E-03 0,04248015 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 8,746E-03 0,04239586 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 8,746E-03 0,04231191 ! base conversion or substitution editing GO:0016553 6 6 0,000 8,746E-03 0,04222829 ! subpallium development GO:0021544 15 6 0,000 8,746E-03 0,042145 ! neural tube patterning GO:0021532 8 6 0,000 8,746E-03 0,04206203 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 8,746E-03 0,0419794 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 8,746E-03 0,04189709 ! maintenance of organ identity GO:0048496 9 6 0,000 8,746E-03 0,04181509 ! G2 phase GO:0051319 16 6 0,000 8,746E-03 0,04173342 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 8,746E-03 0,04165207 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 8,746E-03 0,04157104 ! oxygen homeostasis GO:0032364 10 6 0,000 8,746E-03 0,04149032 ! establishment of planar polarity GO:0001736 7 6 0,000 8,746E-03 0,04140991 ! regulation of mast cell activation GO:0033003 13 6 0,000 8,746E-03 0,04132981 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,746E-03 0,04125003 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 8,746E-03 0,04117055 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,746E-03 0,04109137 ! receptor internalization GO:0031623 11 6 0,000 8,746E-03 0,0410125 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 8,746E-03 0,04093393 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 8,746E-03 0,04085567 ! neutrophil homeostasis GO:0001780 11 6 0,000 8,746E-03 0,0407777 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,746E-03 0,04070003 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 8,746E-03 0,04062265 ! protein deubiquitination GO:0016579 16 6 0,000 8,746E-03 0,04054557 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 8,746E-03 0,04046878 ! protein destabilization GO:0031648 9 6 0,000 8,746E-03 0,04039227 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 8,746E-03 0,04031606 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 8,746E-03 0,04024014 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 8,746E-03 0,0401645 ! regulation of viral transcription GO:0046782 11 6 0,000 8,746E-03 0,04008914 ! progesterone metabolic process GO:0042448 12 6 0,000 8,746E-03 0,04001407 ! negative regulation of axon extension GO:0030517 24 6 0,000 8,746E-03 0,03993928 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 8,746E-03 0,03986476 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 8,746E-03 0,03979053 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,746E-03 0,03971657 ! determination of adult lifespan GO:0008340 17 6 0,000 8,746E-03 0,03964288 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 8,746E-03 0,03956947 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 8,746E-03 0,03949633 ! neural plate development GO:0001840 9 6 0,000 8,746E-03 0,03942346 ! catecholamine transport GO:0051937 9 6 0,000 8,746E-03 0,03935085 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 8,746E-03 0,03927852 ! sensory cilium assembly GO:0035058 10 6 0,000 8,746E-03 0,03920645 ! organ or tissue specific immune response GO:0002251 8 6 0,000 8,746E-03 0,03913464 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 8,746E-03 0,0390631 ! maternal placenta development GO:0001893 12 6 0,000 8,746E-03 0,03899181 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 8,746E-03 0,03892079 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,746E-03 0,03885002 ! negative regulation of B cell activation GO:0050869 14 6 0,000 8,746E-03 0,03877952 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 8,746E-03 0,03870926 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 8,746E-03 0,03863926 ! positive regulation of coagulation GO:0050820 13 6 0,000 8,746E-03 0,03856952 ! cellular anion homeostasis GO:0030002 11 6 0,000 8,746E-03 0,03850002 GO:0055081|anion homeostasis, ! response to protein stimulus GO:0051789 158 96 1,000 8,768E-03 0,03852434 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 8,944E-03 0,03922827 ! tRNA transcription GO:0009304 17 7 0,000 0,01019685 0,04464319 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01019685 0,04456333 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01019685 0,04448375 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01019685 0,04440446 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01019685 0,04432545 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01019685 0,04424671 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01019685 0,04416826 ! sleep GO:0030431 16 7 0,000 0,01019685 0,04409009 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01019685 0,04401219 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01019685 0,04393457 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01019685 0,04385722 ! prostate gland development GO:0030850 14 7 0,000 0,01019685 0,04378014 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01019685 0,04370333 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01019685 0,0436268 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01019685 0,04355053 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01019685 0,04347452 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01019685 0,04339878 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01019685 0,04332331 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01019685 0,04324809 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01019685 0,04317314 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01019685 0,04309844 ! glycolipid transport GO:0046836 11 7 0,000 0,01019685 0,04302401 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01019685 0,04294983 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01019685 0,0428759 ! neuron adhesion GO:0007158 14 7 0,000 0,01019685 0,04280223 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01019685 0,04272882 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01019685 0,04265565 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01019685 0,04258274 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01019685 0,04251007 ! mRNA stabilization GO:0048255 18 7 0,000 0,01019685 0,04243765 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01019685 0,04236548 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01019685 0,04229355 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01019685 0,04222187 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01019685 0,04215042 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01019685 0,04207922 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01019685 0,04200826 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01019685 0,04193754 ! lipoprotein transport GO:0042953 14 7 0,000 0,01019685 0,04186706 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01019685 0,04179681 ! rhythmic behavior GO:0007622 17 7 0,000 0,01019685 0,0417268 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01019685 0,04165702 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01019685 0,04158748 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01019685 0,04151817 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01019685 0,04144909 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01019685 0,04138023 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01019685 0,04131161 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01019685 0,04124321 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01019685 0,04117504 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01019685 0,0411071 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01019685 0,04103937 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01019685 0,04097188 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01019685 0,0409046 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01019685 0,04083754 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01019685 0,0407707 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01019685 0,04070409 ! spinal cord patterning GO:0021511 14 7 0,000 0,01019685 0,04063768 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01019685 0,0405715 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01019685 0,04050553 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01019685 0,04043977 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01019685 0,04037423 ! adrenal gland development GO:0030325 17 7 0,000 0,01019685 0,0403089 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01019685 0,04024378 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01019685 0,04017887 ! ovulation GO:0030728 10 7 0,000 0,01019685 0,04011417 ! adenohypophysis development GO:0021984 11 7 0,000 0,01019685 0,04004968 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01019685 0,03998539 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01019685 0,03992131 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01019685 0,03985744 ! microtubule nucleation GO:0007020 21 7 0,000 0,01019685 0,03979377 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01019685 0,0397303 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01019685 0,03966704 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01019685 0,03960398 ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01019685 0,03954111 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01019685 0,03947845 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01019685 0,03941598 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01019685 0,03935371 ! galactose metabolic process GO:0006012 13 7 0,000 0,01019685 0,03929164 ! vesicle fusion GO:0006906 20 7 0,000 0,01019685 0,03922976 ! response to dietary excess GO:0002021 8 7 0,000 0,01019685 0,03916808 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01019685 0,03910659 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01019685 0,0390453 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01019685 0,03898419 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01019685 0,03892328 ! organ growth GO:0035265 15 7 0,000 0,01019685 0,03886256 ! nucleoside transport GO:0015858 11 7 0,000 0,01019685 0,03880203 ! nucleoside salvage GO:0043174 11 7 0,000 0,01019685 0,03874168 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01019685 0,03868152 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01019685 0,03862155 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01019685 0,03856177 ! parturition GO:0007567 16 7 0,000 0,01019685 0,03850216 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01019685 0,03844275 ! rRNA modification GO:0000154 14 7 0,000 0,01019685 0,03838351 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01019685 0,03832446 ! spindle checkpoint GO:0031577 16 7 0,000 0,01019685 0,03826559 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01019685 0,0382069 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01019685 0,03814839 ! monocyte differentiation GO:0030224 16 7 0,000 0,01019685 0,03809006 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01019685 0,03803191 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01019685 0,03797393 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01019685 0,03791613 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01019685 0,03785851 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01019685 0,03780106 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01019685 0,03774379 ! fibrinolysis GO:0042730 11 7 0,000 0,01019685 0,03768669 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01019685 0,03762976 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01019685 0,037573 ! eating behavior GO:0042755 8 7 0,000 0,01019685 0,03751642 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01019685 0,03746 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01019685 0,03740375 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01019685 0,03734768 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01019685 0,03729177 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01019685 0,03723602 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01019685 0,03718045 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01019685 0,03712504 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01019685 0,03706979 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01019685 0,03701471 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01019685 0,03695979 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01019685 0,03690504 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01019685 0,03685044 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01019685 0,03679601 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01019685 0,03674174 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01019685 0,03668763 ! histone ubiquitination GO:0016574 9 7 0,000 0,01019685 0,03663368 ! regulation of meiosis GO:0040020 12 7 0,000 0,01019685 0,03657988 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01019685 0,03652625 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01019685 0,03647277 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01019685 0,03641945 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01019685 0,03636628 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01019685 0,03631327 ! transcription termination GO:0006353 14 7 0,000 0,01019685 0,03626041 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01019685 0,0362077 ! anaphase GO:0051322 18 7 0,000 0,01019685 0,03615515 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01019685 0,03610275 ! axonal fasciculation GO:0007413 19 7 0,000 0,01019685 0,03605051 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01019685 0,03599841 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01019685 0,03594647 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01019685 0,03589467 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01019685 0,03584302 ! diuresis GO:0030146 12 7 0,000 0,01019685 0,03579152 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01019685 0,03574017 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01019685 0,03568897 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01019685 0,03563791 ! antibiotic transport GO:0042891 9 7 0,000 0,01019685 0,035587 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01019685 0,03553623 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01019685 0,03548561 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01019685 0,03543514 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01019685 0,0353848 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01019685 0,03533461 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01019685 0,03528456 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01019685 0,03523465 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01019685 0,03518489 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01019685 0,03513526 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01019685 0,03508578 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01019685 0,03503643 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01019685 0,03498722 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01019685 0,03493815 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01019685 0,03488922 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01019685 0,03484042 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01019685 0,03479176 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01019685 0,03474324 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01019685 0,03469485 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01019685 0,03464659 ! muscle adaptation GO:0043500 13 7 0,000 0,01019685 0,03459847 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01019685 0,03455049 ! retina homeostasis GO:0001895 12 7 0,000 0,01019685 0,03450263 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01019685 0,03445491 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01019685 0,03440732 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01019685 0,03435986 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01019685 0,03431254 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01164519 0,03913233 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01164519 0,03907857 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01164519 0,03902497 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01164519 0,03897151 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01164519 0,0389182 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01164519 0,03886503 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01164519 0,03881201 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01164519 0,03875913 ! male meiosis GO:0007140 9 8 0,000 0,01164519 0,0387064 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01164519 0,03865381 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01164519 0,03860136 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01164519 0,03854905 ! meiotic prophase I GO:0007128 14 8 0,000 0,01164519 0,03849689 ! response to zinc ion GO:0010043 12 8 0,000 0,01164519 0,03844487 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01164519 0,03839299 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01164519 0,03834124 ! oligopeptide transport GO:0006857 16 8 0,000 0,01164519 0,03828964 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01164519 0,03823818 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01164519 0,03818685 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01164519 0,03813566 ! signal peptide processing GO:0006465 12 8 0,000 0,01164519 0,03808461 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01164519 0,03803369 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01164519 0,03798291 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01164519 0,03793227 ! succinate metabolic process GO:0006105 17 8 0,000 0,01164519 0,03788176 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01164519 0,03783139 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01164519 0,03778115 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01164519 0,03773104 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01164519 0,03768106 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01164519 0,03763122 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01164519 0,03758151 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01164519 0,03753193 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01164519 0,03748248 ! reflex GO:0060004 17 8 0,000 0,01164519 0,03743316 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01164519 0,03738397 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01164519 0,03733491 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01164519 0,03728598 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01164519 0,03723718 ! pigment granule organization GO:0048753 17 8 0,000 0,01164519 0,0371885 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01164519 0,03713995 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01164519 0,03709153 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01164519 0,03704323 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01164519 0,03699506 ! histidine catabolic process GO:0006548 10 8 0,000 0,01164519 0,03694702 GO:0009077|histidine family amino acid catabolic process, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01164519 0,0368991 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01164519 0,0368513 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01164519 0,03680363 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01164519 0,03675608 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01164519 0,03670865 ! melanin metabolic process GO:0006582 17 8 0,000 0,01164519 0,03666134 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01164519 0,03661416 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01164519 0,0365671 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01164519 0,03652016 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01164519 0,03647334 ! macrophage activation GO:0042116 13 8 0,000 0,01164519 0,03642664 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01164519 0,03638005 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01164519 0,03633359 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01164519 0,03628725 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01164519 0,03624102 ! purine salvage GO:0043101 12 8 0,000 0,01164519 0,03619491 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01164519 0,03614892 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01164519 0,03610305 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01164519 0,03605729 ! osteoblast development GO:0002076 17 8 0,000 0,01164519 0,03601165 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01164519 0,03596612 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01164519 0,03592071 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01164519 0,03587541 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01164519 0,03583023 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01164519 0,03578516 ! response to UV-B GO:0010224 17 8 0,000 0,01164519 0,0357402 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01164519 0,03569536 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01164519 0,03565063 ! intermediate filament organization GO:0045109 12 8 0,000 0,01164519 0,03560601 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01164519 0,0355615 ! cellular extravasation GO:0045123 13 8 0,000 0,01164519 0,03551711 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01164519 0,03547282 ! response to antibiotic GO:0046677 11 8 0,000 0,01164519 0,03542865 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01164519 0,03538458 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01164519 0,03534062 ! DNA topological change GO:0006265 12 8 0,000 0,01164519 0,03529678 ! response to tropane GO:0014073 15 8 0,000 0,01164519 0,03525304 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01164519 0,03520941 ! melanosome transport GO:0032402 13 8 0,000 0,01164519 0,03516589 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01164519 0,03512247 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01164519 0,03507916 ! mast cell activation GO:0045576 14 8 0,000 0,01164519 0,03503596 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01164519 0,03499287 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01164519 0,03494988 ! gas homeostasis GO:0033483 14 8 0,000 0,01164519 0,034907 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01164519 0,03486422 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01164519 0,03482155 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01164519 0,03477898 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01164519 0,03473651 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01164519 0,03469415 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01164519 0,03465189 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01164519 0,03460974 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01164519 0,03456768 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01164519 0,03452573 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01164519 0,03448388 ! response to tumor cell GO:0002347 16 8 0,000 0,01164519 0,03444213 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01164519 0,03440049 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01164519 0,03435894 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01164519 0,03431749 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01164519 0,03427615 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01164519 0,0342349 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01164519 0,03419375 ! hormone catabolic process GO:0042447 17 8 0,000 0,01164519 0,0341527 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01164519 0,03411175 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01164519 0,0340709 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01164519 0,03403015 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01164519 0,03398949 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01164519 0,03394893 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01164519 0,03390847 ! adult feeding behavior GO:0008343 10 8 0,000 0,01164519 0,0338681 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01164519 0,03382783 ! ATP catabolic process GO:0006200 11 8 0,000 0,01164519 0,03378765 ! blastocyst growth GO:0001832 19 8 0,000 0,01164519 0,03374757 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01164519 0,03370759 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01164519 0,0336677 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01164519 0,0336279 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01164519 0,0335882 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01164519 0,03354859 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01164519 0,03350907 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01164519 0,03346965 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01164519 0,03343032 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01164519 0,03339108 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01164519 0,03335194 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01164519 0,03331288 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01164519 0,03327392 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01164519 0,03323505 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01164519 0,03319627 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01164519 0,03315758 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01164519 0,03311898 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01164519 0,03308047 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01164519 0,03304205 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01164519 0,03300372 ! axon extension GO:0048675 16 9 0,000 0,01309146 0,03705959 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01309146 0,0370167 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01309146 0,0369739 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01309146 0,03693121 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01309146 0,03688861 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01309146 0,03684611 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01309146 0,03680371 ! reproductive behavior GO:0019098 22 9 0,000 0,01309146 0,03676141 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01309146 0,0367192 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01309146 0,03667709 ! UTP metabolic process GO:0046051 10 9 0,000 0,01309146 0,03663508 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01309146 0,03659316 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01309146 0,03655134 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01309146 0,03650962 ! artery development GO:0060840 25 9 0,000 0,01309146 0,03646799 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01309146 0,03642645 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01309146 0,03638501 ! equilibrioception GO:0050957 20 9 0,000 0,01309146 0,03634367 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01309146 0,03630241 ! chemosensory behavior GO:0007635 21 9 0,000 0,01309146 0,03626125 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01309146 0,03622019 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01309146 0,03617922 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01309146 0,03613833 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01309146 0,03609755 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01309146 0,03605685 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01309146 0,03601625 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01309146 0,03597573 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01309146 0,03593531 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01309146 0,03589498 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01309146 0,03585474 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01309146 0,03581459 ! protein targeting to ER GO:0045047 25 9 0,000 0,01309146 0,03577453 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01309146 0,03573455 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01309146 0,03569467 ! T cell selection GO:0045058 27 9 0,000 0,01309146 0,03565488 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01309146 0,03561517 ! glycine catabolic process GO:0006546 15 9 0,000 0,01309146 0,03557556 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01309146 0,03553603 ! endosome organization GO:0007032 20 9 0,000 0,01309146 0,03549659 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01309146 0,03545724 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01309146 0,03541797 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01309146 0,03537879 ! mannose metabolic process GO:0006013 13 9 0,000 0,01309146 0,0353397 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01309146 0,03530069 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01309146 0,03526177 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01309146 0,03522294 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01309146 0,03518419 ! receptor clustering GO:0043113 20 9 0,000 0,01309146 0,03514552 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01309146 0,03510694 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01309146 0,03506845 ! retinol metabolic process GO:0042572 20 9 0,000 0,01309146 0,03503004 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01309146 0,03499171 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01309146 0,03495347 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01309146 0,03491531 ! macrophage differentiation GO:0030225 15 9 0,000 0,01309146 0,03487724 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01309146 0,03483924 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01309146 0,03480133 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01309146 0,03476351 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01309146 0,03472576 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01309146 0,0346881 ! response to amine stimulus GO:0014075 13 9 0,000 0,01309146 0,03465052 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01309146 0,03461302 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01309146 0,0345756 ! erythrocyte development GO:0048821 17 9 0,000 0,01309146 0,03453826 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01309146 0,034501 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01309146 0,03446382 ! renal water homeostasis GO:0003091 15 9 0,000 0,01309146 0,03442672 ! postreplication repair GO:0006301 25 9 0,000 0,01309146 0,03438971 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01309146 0,03435277 ! icosanoid secretion GO:0032309 15 9 0,000 0,01309146 0,03431591 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01309146 0,03427913 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01309146 0,03424243 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01309146 0,0342058 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01309146 0,03416926 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01309146 0,03413279 ! sterol catabolic process GO:0016127 14 9 0,000 0,01309146 0,0340964 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01309146 0,03406009 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01309146 0,03402386 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01309146 0,0339877 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01309146 0,03395162 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01309146 0,03391562 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01309146 0,03387969 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01309146 0,03384384 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01309146 0,03380806 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01309146 0,03377236 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01309146 0,03373674 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01309146 0,03370119 ! purine base metabolic process GO:0006144 25 9 0,000 0,01309146 0,03366571 ! pigment granule transport GO:0051904 17 9 0,000 0,01309146 0,03363031 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01309146 0,03359499 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01309146 0,03355973 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01309146 0,03352456 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01309146 0,03348945 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01309146 0,03345442 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01309146 0,03341946 ! mitochondrion localization GO:0051646 18 9 0,000 0,01309146 0,03338458 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01453564 0,03702876 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01453564 0,03699019 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01453564 0,0369517 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01453564 0,03691328 ! associative learning GO:0008306 21 10 0,000 0,01453564 0,03687495 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01453564 0,0368367 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01453564 0,03679853 ! phosphate transport GO:0006817 24 10 0,000 0,01453564 0,03676043 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01453564 0,03672242 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01453564 0,03668448 ! CTP metabolic process GO:0046036 11 10 0,000 0,01453564 0,03664662 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01453564 0,03660884 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01453564 0,03657114 ! GTP metabolic process GO:0046039 11 10 0,000 0,01453564 0,03653352 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01453564 0,03649597 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01453564 0,0364585 ! social behavior GO:0035176 29 10 0,000 0,01453564 0,03642111 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01453564 0,03638379 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01453564 0,03634655 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01453564 0,03630939 ! androgen metabolic process GO:0008209 17 10 0,000 0,01453564 0,0362723 ! phospholipid efflux GO:0033700 19 10 0,000 0,01453564 0,03623528 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01453564 0,03619835 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01453564 0,03616149 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01453564 0,0361247 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01453564 0,03608799 ! lung alveolus development GO:0048286 26 10 0,000 0,01453564 0,03605135 ! pathogenesis GO:0009405 17 10 0,000 0,01453564 0,03601479 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01453564 0,0359783 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01453564 0,03594188 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01453564 0,03590554 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01453564 0,03586927 ! endoderm development GO:0007492 18 10 0,000 0,01453564 0,03583308 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01453564 0,03579695 ! arginine catabolic process GO:0006527 17 10 0,000 0,01453564 0,03576091 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01453564 0,03572493 ! proline metabolic process GO:0006560 13 10 0,000 0,01453564 0,03568902 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01453564 0,03565319 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01453564 0,03561743 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01453564 0,03558174 ! V(D)J recombination GO:0033151 34 10 0,000 0,01453564 0,03554613 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01453564 0,03551058 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01453564 0,0354751 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01453564 0,0354397 ! B cell proliferation GO:0042100 19 10 0,000 0,01453564 0,03540437 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01453564 0,0353691 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01453564 0,03533391 ! multicellular organism growth GO:0035264 19 10 0,000 0,01453564 0,03529879 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01453564 0,03526373 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01453564 0,03522875 ! ruffle organization GO:0031529 17 10 0,000 0,01453564 0,03519383 ! epithelial cell development GO:0002064 21 10 0,000 0,01453564 0,03515899 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01453564 0,03512421 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01453564 0,03508951 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01453564 0,03505487 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01453564 0,03502029 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01453564 0,03498579 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01453564 0,03495136 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01453564 0,03491699 ! motor axon guidance GO:0008045 22 10 0,000 0,01453564 0,03488269 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01453564 0,03484846 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01453564 0,03481429 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01453564 0,0347802 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01453564 0,03474616 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01453564 0,0347122 ! segment specification GO:0007379 15 10 0,000 0,01453564 0,0346783 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01453564 0,03464447 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01453564 0,0346107 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01453564 0,034577 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01453564 0,03454336 ! response to dsRNA GO:0043331 23 10 0,000 0,01453564 0,0345098 ! DNA ligation GO:0006266 18 10 0,000 0,01453564 0,03447629 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01453564 0,03444285 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01453564 0,03440948 ! melanosome localization GO:0032400 16 10 0,000 0,01453564 0,03437617 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01453564 0,03434292 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01453564 0,03430974 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01453564 0,03427662 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01453564 0,03424357 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01453564 0,03421058 ! induction of an organ GO:0001759 17 10 0,000 0,01453564 0,03417765 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01453564 0,03414479 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01453564 0,03411199 ! protein sumoylation GO:0016925 17 10 0,000 0,01453564 0,03407925 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01453564 0,03404658 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01453564 0,03401396 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01453564 0,03398142 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01453564 0,03394893 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01453564 0,0339165 ! salivary gland development GO:0007431 28 10 0,000 0,01453564 0,03388414 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01453564 0,03385184 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01453564 0,0338196 ! midbrain development GO:0030901 14 10 0,000 0,01453564 0,03378742 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01453564 0,0337553 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01453564 0,03372325 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01453564 0,03369125 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01453564 0,03365932 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01453564 0,03362744 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01453564 0,03359563 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01453564 0,03356387 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01453564 0,03353218 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01453564 0,03350055 ! detection of calcium ion GO:0005513 24 10 0,000 0,01453564 0,03346897 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01453564 0,03343746 ! blastocyst formation GO:0001825 18 10 0,000 0,01453564 0,033406 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01453564 0,0333746 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01453564 0,03334327 ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01453564 0,03331199 ! response to nicotine GO:0035094 20 10 0,000 0,01453564 0,03328077 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01453564 0,03324961 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01597776 0,03651419 ! respiratory burst GO:0045730 17 11 0,000 0,01597776 0,03648006 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01597776 0,036446 ! neuron fate specification GO:0048665 18 11 0,000 0,01597776 0,036412 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01597776 0,03637807 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01597776 0,0363442 ! thyroid gland development GO:0030878 26 11 0,000 0,01597776 0,03631039 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01597776 0,03627664 ! synapsis GO:0007129 14 11 0,000 0,01597776 0,03624296 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01597776 0,03620934 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01597776 0,03617578 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01597776 0,03614229 ! response to pain GO:0048265 27 11 0,000 0,01597776 0,03610885 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01597776 0,03607548 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01597776 0,03604217 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01597776 0,03600892 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01597776 0,03597573 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01597776 0,0359426 ! bone resorption GO:0045453 16 11 0,000 0,01597776 0,03590954 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01597776 0,03587653 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01597776 0,03584359 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01597776 0,0358107 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01597776 0,03577788 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01597776 0,03574512 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01597776 0,03571241 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01597776 0,03567977 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01597776 0,03564719 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01597776 0,03561466 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01597776 0,0355822 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01597776 0,03554979 ! UV protection GO:0009650 20 11 0,000 0,01597776 0,03551744 ! adult heart development GO:0007512 16 11 0,000 0,01597776 0,03548515 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01597776 0,03545292 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01597776 0,03542075 ! macroautophagy GO:0016236 19 11 0,000 0,01597776 0,03538864 ! temperature homeostasis GO:0001659 18 11 0,000 0,01597776 0,03535658 ! behavioral fear response GO:0001662 27 11 0,000 0,01597776 0,03532459 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01597776 0,03529265 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01597776 0,03526077 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01597776 0,03522894 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01597776 0,03519718 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01597776 0,03516547 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01597776 0,03513381 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01597776 0,03510222 ! regulation of organ growth GO:0046620 14 11 0,000 0,01597776 0,03507068 ! pigment granule localization GO:0051875 20 11 0,000 0,01597776 0,0350392 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01597776 0,03500777 ! vasoconstriction GO:0042310 20 11 0,000 0,01597776 0,03497641 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01597776 0,03494509 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01597776 0,03491384 ! embryonic axis specification GO:0000578 19 11 0,000 0,01597776 0,03488263 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01597776 0,03485149 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01597776 0,0348204 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01597776 0,03478937 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01597776 0,03475839 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01597776 0,03472746 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01597776 0,03469659 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01597776 0,03466578 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01597776 0,03463502 ! prophase GO:0051324 17 11 0,000 0,01597776 0,03460432 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01597776 0,03457367 ! nucleosome positioning GO:0016584 15 11 0,000 0,01597776 0,03454307 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01597776 0,03451253 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01597776 0,03448204 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01597776 0,0344516 ! apical protein localization GO:0045176 18 11 0,000 0,01597776 0,03442122 ! acid secretion GO:0046717 20 11 0,000 0,01597776 0,0343909 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01597776 0,03436062 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01597776 0,0343304 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01597776 0,03430024 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01597776 0,03427012 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01597776 0,03424006 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01597776 0,03421005 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01597776 0,03418009 ! cholesterol efflux GO:0033344 21 11 0,000 0,01597776 0,03415019 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01597776 0,03412034 ! oocyte development GO:0048599 20 11 0,000 0,01597776 0,03409054 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01597776 0,03406079 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01597776 0,0340311 ! embryonic gut development GO:0048566 19 11 0,000 0,01597776 0,03400145 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01597776 0,03397186 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01597776 0,03394232 ! activation of innate immune response GO:0002218 16 11 0,000 0,01597776 0,03391283 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01597776 0,03388339 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01597776 0,03385401 ! lysogeny GO:0030069 22 11 0,000 0,01597776 0,03382467 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01597776 0,03379538 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01597776 0,03376615 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01597776 0,03373696 ! nucleus localization GO:0051647 22 11 0,000 0,01597776 0,03370783 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01741781 0,03671415 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01741781 0,0366825 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01741781 0,03665091 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01741781 0,03661936 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01741781 0,03658788 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01741781 0,03655644 ! protein complex disassembly GO:0043241 28 12 0,000 0,01741781 0,03652507 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01741781 0,03649374 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01741781 0,03646247 ! hippocampus development GO:0021766 29 12 0,000 0,01741781 0,03643125 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01741781 0,03640009 ! T cell proliferation GO:0042098 32 12 0,000 0,01741781 0,03636898 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01741781 0,03633792 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01741781 0,03630691 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01741781 0,03627596 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01741781 0,03624506 ! drug transport GO:0015893 16 12 0,000 0,01741781 0,03621421 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01741781 0,03618342 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01741781 0,03615268 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01741781 0,03612199 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01741781 0,03609135 ! focal adhesion formation GO:0048041 37 12 0,000 0,01741781 0,03606076 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01741781 0,03603023 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01741781 0,03599975 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01741781 0,03596932 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01741781 0,03593894 ! lipid digestion GO:0044241 21 12 0,000 0,01741781 0,03590861 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01741781 0,03587833 ! entry into host cell GO:0030260 34 12 0,000 0,01741781 0,03584811 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01741781 0,03581793 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01741781 0,03578781 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01741781 0,03575773 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01741781 0,03572771 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01741781 0,03569774 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01741781 0,03566781 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01741781 0,03563794 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01741781 0,03560812 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01741781 0,03557835 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01741781 0,03554862 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01741781 0,03551895 ! cranial nerve development GO:0021545 23 12 0,000 0,01741781 0,03548933 ! fucose catabolic process GO:0019317 25 12 0,000 0,01741781 0,03545975 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01741781 0,03543023 ! histone acetylation GO:0016573 27 12 0,000 0,01741781 0,03540075 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01741781 0,03537132 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01741781 0,03534194 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01741781 0,03531261 ! zymogen activation GO:0031638 18 12 0,000 0,01741781 0,03528333 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01741781 0,0352541 ! T cell homeostasis GO:0043029 28 12 0,000 0,01741781 0,03522492 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01741781 0,03519578 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01741781 0,03516669 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01741781 0,03513766 ! oocyte differentiation GO:0009994 21 12 0,000 0,01741781 0,03510866 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01741781 0,03507972 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01741781 0,03505082 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01741781 0,03502198 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01741781 0,03499317 ! defense response to fungus GO:0050832 15 12 0,000 0,01741781 0,03496442 ! developmental induction GO:0031128 22 12 0,000 0,01741781 0,03493571 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01741781 0,03490706 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01741781 0,03487844 ! response to cold GO:0009409 17 12 0,000 0,01741781 0,03484988 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01741781 0,03482136 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01741781 0,03479289 ! localization within membrane GO:0051668 26 12 0,000 0,01741781 0,03476446 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01885579 0,03760382 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01885579 0,03757315 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01885579 0,03754253 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01885579 0,03751196 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01885579 0,03748144 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01885579 0,03745096 ! peroxisomal transport GO:0043574 28 13 0,000 0,01885579 0,03742054 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01885579 0,03739017 ! cartilage condensation GO:0001502 22 13 0,000 0,01885579 0,03735984 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01885579 0,03732957 ! organelle fusion GO:0048284 36 13 0,000 0,01885579 0,03729934 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01885579 0,03726916 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01885579 0,03723903 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01885579 0,03720895 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01885579 0,03717892 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01885579 0,03714894 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01885579 0,037119 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01885579 0,03708912 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01885579 0,03705928 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01885579 0,03702949 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01885579 0,03699975 ! methionine metabolic process GO:0006555 31 13 0,000 0,01885579 0,03697005 ! plasma membrane organization GO:0007009 27 13 0,000 0,01885579 0,0369404 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01885579 0,0369108 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01885579 0,03688125 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01885579 0,03685175 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01885579 0,03682229 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01885579 0,03679288 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01885579 0,03676351 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01885579 0,0367342 ! exocrine system development GO:0035272 34 13 0,000 0,01885579 0,03670493 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01885579 0,0366757 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01885579 0,03664653 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01885579 0,0366174 ! L-glutamate transport GO:0015813 30 13 0,000 0,01885579 0,03658831 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01885579 0,03655927 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01885579 0,03653028 ! protein homotetramerization GO:0051289 24 13 0,000 0,01885579 0,03650133 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01885579 0,03647243 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01885579 0,03644358 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01885579 0,03641477 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01885579 0,03638601 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01885579 0,03635729 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01885579 0,03632861 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01885579 0,03629999 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01885579 0,0362714 ! histone methylation GO:0016571 29 13 0,000 0,01885579 0,03624287 ! chromatin silencing GO:0006342 29 13 0,000 0,01885579 0,03621437 ! gland morphogenesis GO:0022612 31 13 0,000 0,01885579 0,03618593 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01885579 0,03615752 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01885579 0,03612916 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01885579 0,03610085 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01885579 0,03607258 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01885579 0,03604435 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01885579 0,03601617 ! spleen development GO:0048536 24 13 0,000 0,01885579 0,03598803 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01885579 0,03595994 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01885579 0,03593189 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01885579 0,03590388 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01885579 0,03587592 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01885579 0,035848 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01885579 0,03582013 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01885579 0,0357923 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01885579 0,03576451 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01885579 0,03573676 ! insulin secretion GO:0030073 24 13 0,000 0,01885579 0,03570906 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01885579 0,0356814 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01885579 0,03565378 ! acrosome reaction GO:0007340 19 13 0,000 0,01885579 0,03562621 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01885579 0,03559867 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01885579 0,03557118 ! rRNA transcription GO:0009303 28 14 0,000 0,0202917 0,03825048 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0202917 0,03822099 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0202917 0,03819154 ! water transport GO:0006833 21 14 0,000 0,0202917 0,03816214 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0202917 0,03813279 ! non-recombinational repair GO:0000726 29 14 0,000 0,0202917 0,03810348 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0202917 0,03807421 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,0202917 0,03804499 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,0202917 0,03801582 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0202917 0,03798669 ! lipid localization GO:0010876 32 14 0,000 0,0202917 0,0379576 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0202917 0,03792856 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,0202917 0,03789956 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0202917 0,03787061 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0202917 0,0378417 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0202917 0,03781283 ! arginine metabolic process GO:0006525 21 14 0,000 0,0202917 0,03778401 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0202917 0,03775524 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,0202917 0,0377265 ! regulation of heart rate GO:0002027 25 14 0,000 0,0202917 0,03769781 ! fear response GO:0042596 34 14 0,000 0,0202917 0,03766917 ! organic alcohol transport GO:0015850 29 14 0,000 0,0202917 0,03764057 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0202917 0,03761201 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,0202917 0,03758349 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0202917 0,03755502 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0202917 0,03752659 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0202917 0,0374982 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,0202917 0,03746986 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0202917 0,03744156 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,0202917 0,0374133 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0202917 0,03738509 ! regulation of cellular pH GO:0030641 27 14 0,000 0,0202917 0,03735691 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0202917 0,03732878 ! ribosome assembly GO:0042255 18 14 0,000 0,0202917 0,0373007 ! cerebellum development GO:0021549 23 14 0,000 0,0202917 0,03727265 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,0202917 0,03724465 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0202917 0,03721668 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0202917 0,03718877 ! response to gamma radiation GO:0010332 30 14 0,000 0,0202917 0,03716089 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,0202917 0,03713305 ! NADP metabolic process GO:0006739 24 14 0,000 0,0202917 0,03710526 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0202917 0,03707751 ! oxygen transport GO:0015671 22 14 0,000 0,0202917 0,03704979 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0202917 0,03702212 ! male genitalia development GO:0030539 26 14 0,000 0,0202917 0,0369945 ! regulation of RNA stability GO:0043487 33 14 0,000 0,0202917 0,03696691 ! regulation of axon extension GO:0030516 43 14 0,000 0,0202917 0,03693936 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,0202917 0,03691186 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0202917 0,03688439 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0202917 0,03685697 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02172555 0,03943204 ! lactation GO:0007595 30 15 0,000 0,02172555 0,03940277 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02172555 0,03937354 ! reproductive cellular process GO:0048610 22 15 0,000 0,02172555 0,03934435 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02172555 0,03931521 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02172555 0,03928611 ! superoxide anion generation GO:0042554 22 15 0,000 0,02172555 0,03925705 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02172555 0,03922803 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02172555 0,03919906 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02172555 0,03917013 ! copper ion transport GO:0006825 22 15 0,000 0,02172555 0,03914125 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02172555 0,0391124 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02172555 0,0390836 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02172555 0,03905484 ! sulfate transport GO:0008272 27 15 0,000 0,02172555 0,03902612 ! response to cAMP GO:0051591 25 15 0,000 0,02172555 0,03899745 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02172555 0,03896882 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02172555 0,03894023 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02172555 0,03891168 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02172555 0,03888317 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02172555 0,03885471 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02172555 0,03882628 ! vesicle coating GO:0006901 38 15 0,000 0,02172555 0,0387979 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02172555 0,03876956 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02172555 0,03874126 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02172555 0,038713 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02172555 0,03868479 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02172555 0,03865661 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02172555 0,03862848 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02172555 0,03860039 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02172555 0,03857233 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02172555 0,03854432 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02172555 0,03851635 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02172555 0,03848842 ! histone deacetylation GO:0016575 24 15 0,000 0,02172555 0,03846053 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02172555 0,03843268 ! water homeostasis GO:0030104 28 15 0,000 0,02172555 0,03840487 ! cofactor transport GO:0051181 30 15 0,000 0,02172555 0,0383771 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02172555 0,03834937 ! muscle maintenance GO:0046716 26 15 0,000 0,02172555 0,03832168 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02172555 0,03829403 ! intestinal absorption GO:0050892 31 15 0,000 0,02172555 0,03826642 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02172555 0,03823885 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02172555 0,03821132 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02172555 0,03818383 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02172555 0,03815638 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02172555 0,03812897 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02172555 0,0381016 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02172555 0,03807427 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02172555 0,03804697 ! actin filament polymerization GO:0030041 27 15 0,000 0,02172555 0,03801972 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02172555 0,03799251 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02315735 0,04046739 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02315735 0,04043846 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02315735 0,04040958 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02315735 0,04038073 ! bone remodeling GO:0046849 28 16 0,000 0,02315735 0,04035193 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02315735 0,04032317 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02315735 0,04029445 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02315735 0,04026577 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02315735 0,04023713 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02315735 0,04020853 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02315735 0,04017998 ! startle response GO:0001964 28 16 0,000 0,02315735 0,04015146 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02315735 0,04012298 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02315735 0,04009455 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02315735 0,04006615 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02315735 0,0400378 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02315735 0,04000948 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02315735 0,03998121 ! pituitary gland development GO:0021983 30 16 0,000 0,02315735 0,03995297 ! response to osmotic stress GO:0006970 27 16 0,000 0,02315735 0,03992478 ! lysosomal transport GO:0007041 31 16 0,000 0,02315735 0,03989662 ! fructose metabolic process GO:0006000 25 16 0,000 0,02315735 0,0398685 ! L-amino acid transport GO:0015807 33 16 0,000 0,02315735 0,03984043 ! stem cell development GO:0048864 46 16 0,000 0,02315735 0,03981239 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02315735 0,03978439 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02315735 0,03975643 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02315735 0,03972852 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02315735 0,03970064 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02315735 0,0396728 ! axon cargo transport GO:0008088 46 16 0,000 0,02315735 0,03964499 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02315735 0,03961723 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02315735 0,03958951 ! DNA replication initiation GO:0006270 28 16 0,000 0,02315735 0,03956182 ! neuron recognition GO:0008038 40 16 0,000 0,02315735 0,03953418 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02315735 0,03950657 ! tissue regeneration GO:0042246 27 16 0,000 0,02315735 0,039479 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02315735 0,03945147 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02315735 0,03942398 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02315735 0,03939652 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02315735 0,03936911 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02315735 0,03934173 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02315735 0,03931439 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02315735 0,03928709 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02315735 0,03925982 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02315735 0,0392326 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02315735 0,03920541 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02315735 0,03917826 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02315735 0,03915115 ! peptide hormone processing GO:0016486 27 16 0,000 0,02315735 0,03912407 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02458709 0,04151089 ! metencephalon development GO:0022037 32 17 0,000 0,02458709 0,04148223 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02458709 0,0414536 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02458709 0,04142501 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02458709 0,04139646 ! signal complex assembly GO:0007172 47 17 0,000 0,02458709 0,04136795 ! filopodium assembly GO:0046847 42 17 0,000 0,02458709 0,04133948 ! endothelial cell migration GO:0043542 31 17 0,000 0,02458709 0,04131105 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02458709 0,04128265 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02458709 0,0412543 ! glial cell development GO:0021782 28 17 0,000 0,02458709 0,04122599 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02458709 0,04119771 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02458709 0,04116947 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02458709 0,04114128 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02458709 0,04111312 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02458709 0,04108499 ! myoblast differentiation GO:0045445 50 17 0,000 0,02458709 0,04105691 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02458709 0,04102887 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02458709 0,04100086 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02458709 0,04097289 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02458709 0,04094496 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02458709 0,04091707 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02458709 0,04088922 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02458709 0,0408614 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02458709 0,04083363 ! membrane budding GO:0006900 42 17 0,000 0,02458709 0,04080588 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02458709 0,04077818 ! regulation of protein binding GO:0043393 33 17 0,000 0,02458709 0,04075052 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02458709 0,04072289 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02458709 0,0406953 ! genitalia development GO:0048806 32 17 0,000 0,02458709 0,04066775 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02458709 0,04064023 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02458709 0,04061275 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02458709 0,04058531 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02458709 0,04055791 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02458709 0,04053054 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02458709 0,04050321 ! steroid catabolic process GO:0006706 34 17 0,000 0,02458709 0,04047592 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02458709 0,04044866 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02458709 0,04042144 ! gas transport GO:0015669 26 17 0,000 0,02458709 0,04039426 ! organic cation transport GO:0015695 32 17 0,000 0,02458709 0,04036711 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02458709 0,04034 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02458709 0,04031293 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02458709 0,04028589 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02601478 0,04259658 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02601478 0,04256805 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02601478 0,04253956 ! limbic system development GO:0021761 40 18 0,000 0,02601478 0,04251111 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02601478 0,04248269 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02601478 0,04245431 ! adult walking behavior GO:0007628 36 18 0,000 0,02601478 0,04242597 ! heart looping GO:0001947 34 18 0,000 0,02601478 0,04239767 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02601478 0,0423694 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02601478 0,04234118 ! centrosome cycle GO:0007098 26 18 0,000 0,02601478 0,04231299 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02601478 0,04228483 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02601478 0,04225672 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02601478 0,04222864 ! glycine metabolic process GO:0006544 30 18 0,000 0,02601478 0,0422006 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02601478 0,0421726 ! response to retinoic acid GO:0032526 31 18 0,000 0,02601478 0,04214463 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02601478 0,0421167 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02601478 0,04208881 ! DNA integration GO:0015074 32 18 0,000 0,02601478 0,04206096 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02601478 0,04203314 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02601478 0,04200536 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02601478 0,04197761 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02601478 0,0419499 ! neural crest cell migration GO:0001755 41 18 0,000 0,02601478 0,04192223 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02601478 0,0418946 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02601478 0,041867 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02601478 0,04183944 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02601478 0,04181191 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02601478 0,04178442 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02601478 0,04175697 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02601478 0,04172955 ! detection of bacterium GO:0016045 22 18 0,000 0,02601478 0,04170217 ! nerve development GO:0021675 34 18 0,000 0,02601478 0,04167482 ! defense response to virus GO:0051607 43 18 0,000 0,02601478 0,04164751 ! microspike assembly GO:0030035 46 18 0,000 0,02601478 0,04162024 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02601478 0,041593 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02601478 0,0415658 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02744042 0,04381499 ! positive regulation of translation GO:0045727 31 19 0,000 0,02744042 0,04378637 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02744042 0,04375779 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02744042 0,04372925 ! neuron maturation GO:0042551 46 19 0,000 0,02744042 0,04370074 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02744042 0,04367227 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02744042 0,04364384 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02744042 0,04361544 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02744042 0,04358709 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02744042 0,04355876 ! inositol metabolic process GO:0006020 33 19 0,000 0,02744042 0,04353048 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02744042 0,04350223 ! memory GO:0007613 34 19 0,000 0,02744042 0,04347402 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02744042 0,04344585 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02744042 0,04341771 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02744042 0,0433896 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02744042 0,04336154 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,02744042 0,04333351 ! cerebral cortex development GO:0021987 40 19 0,000 0,02744042 0,04330552 ! pigmentation during development GO:0048066 42 19 0,000 0,02744042 0,04327756 ! response to vitamin A GO:0033189 32 19 0,000 0,02744042 0,04324964 ! heme metabolic process GO:0042168 40 19 0,000 0,02744042 0,04322175 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02744042 0,0431939 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02744042 0,04316609 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02744042 0,04313831 ! response to fungus GO:0009620 26 19 0,000 0,02744042 0,04311057 ! peptide cross-linking GO:0018149 39 19 0,000 0,02744042 0,04308287 ! protein export from nucleus GO:0006611 40 19 0,000 0,02744042 0,0430552 ! heart process GO:0003015 32 19 0,000 0,02744042 0,04302756 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02744042 0,04299996 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02744042 0,0429724 ! visual learning GO:0008542 38 19 0,000 0,02744042 0,04294487 ! cellular pigmentation GO:0033059 37 19 0,000 0,02744042 0,04291737 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02744042 0,04288992 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02744042 0,04286249 ! vitamin transport GO:0051180 31 19 0,000 0,02744042 0,0428351 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02744042 0,04280775 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02744042 0,04278043 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02744042 0,04275315 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02744042 0,0427259 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02744042 0,04269869 ! cilium assembly GO:0042384 38 19 0,000 0,02744042 0,04267151 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02744042 0,04264436 ! protein secretion GO:0009306 45 20 0,000 0,02886401 0,04482821 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02886401 0,04479973 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02886401 0,04477128 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02886401 0,04474288 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02886401 0,0447145 ! skin development GO:0043588 42 20 0,000 0,02886401 0,04468617 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02886401 0,04465787 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02886401 0,0446296 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,02886401 0,04460137 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02886401 0,04457318 ! response to vitamin GO:0033273 36 20 0,000 0,02886401 0,04454502 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02886401 0,0445169 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02886401 0,04448882 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02886401 0,04446077 ! response to alkaloid GO:0043279 38 20 0,000 0,02886401 0,04443275 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02886401 0,04440477 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02886401 0,04437682 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02886401 0,04434891 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02886401 0,04432104 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02886401 0,0442932 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,02886401 0,04426539 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,02886401 0,04423762 ! actin filament bundle formation GO:0051017 47 20 0,000 0,02886401 0,04420989 ! body fluid secretion GO:0007589 33 20 0,000 0,02886401 0,04418219 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02886401 0,04415452 ! peptide secretion GO:0002790 38 20 0,000 0,02886401 0,04412689 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02886401 0,0440993 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,02886401 0,04407173 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02886401 0,04404421 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02886401 0,04401671 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02886401 0,04398925 ! cell-cell junction organization GO:0045216 43 20 0,000 0,02886401 0,04396183 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,02886401 0,04393444 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02886401 0,04390708 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02886401 0,04387976 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,02886401 0,04385247 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02886401 0,04382522 ! regulation of glucose import GO:0046324 30 20 0,000 0,02886401 0,043798 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02886401 0,04377081 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02886401 0,04374366 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02886401 0,04371654 ! negative regulation of translation GO:0017148 32 20 0,000 0,02886401 0,04368945 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02886401 0,0436624 ! regulation of cell killing GO:0031341 46 21 0,000 0,03028556 0,04578442 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03028556 0,0457561 ! hormone secretion GO:0046879 39 21 0,000 0,03028556 0,04572782 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03028556 0,04569958 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03028556 0,04567137 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03028556 0,04564319 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03028556 0,04561505 ! ovarian follicle development GO:0001541 39 21 0,000 0,03028556 0,04558695 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03028556 0,04555888 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,03028556 0,04553084 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03028556 0,04550284 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03028556 0,04547487 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03028556 0,04544694 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03028556 0,04541904 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03028556 0,04539118 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,03028556 0,04536334 ! sensory perception of pain GO:0019233 33 21 0,000 0,03028556 0,04533555 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03028556 0,04530779 ! diencephalon development GO:0021536 36 21 0,000 0,03028556 0,04528006 ! collagen fibril organization GO:0030199 62 21 0,000 0,03028556 0,04525236 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03028556 0,0452247 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03028556 0,04519708 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03028556 0,04516948 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03028556 0,04514193 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,03028556 0,0451144 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03028556 0,04508691 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03028556 0,04505945 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03028556 0,04503202 ! actin filament-based movement GO:0030048 47 21 0,000 0,03028556 0,04500463 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03028556 0,04497727 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,03170506 0,04705679 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03170506 0,04702822 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03170506 0,04699968 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03170506 0,04697118 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03170506 0,04694271 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03170506 0,04691428 ! microtubule-based transport GO:0010970 59 22 0,000 0,03170506 0,04688588 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03170506 0,04685751 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,03170506 0,04682918 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03170506 0,04680089 ! cellular response to starvation GO:0009267 37 22 0,000 0,03170506 0,04677263 ! vacuolar transport GO:0007034 41 22 0,000 0,03170506 0,0467444 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03170506 0,04671621 ! fucose metabolic process GO:0006004 44 22 0,000 0,03170506 0,04668805 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03170506 0,04665992 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03170506 0,04663183 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03170506 0,04660377 ! ureteric bud development GO:0001657 50 22 0,000 0,03170506 0,04657575 ! cell aging GO:0007569 48 22 0,000 0,03170506 0,04654776 ! stem cell differentiation GO:0048863 57 22 0,000 0,03170506 0,0465198 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03170506 0,04649188 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,03170506 0,04646399 ! cytolysis GO:0019835 27 22 0,000 0,03170506 0,04643613 ! renal system process GO:0003014 42 22 0,000 0,03170506 0,04640831 ! vasodilation GO:0042311 40 22 0,000 0,03170506 0,04638052 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03170506 0,04635277 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03170506 0,04632504 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,03170506 0,04629735 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03170506 0,0462697 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03170506 0,04624207 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03170506 0,04621448 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,03170506 0,04618692 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03170506 0,0461594 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03170506 0,04613191 ! sarcomere organization GO:0045214 32 22 0,000 0,03170506 0,04610445 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,03170506 0,04607702 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03170506 0,04604963 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03170506 0,04602226 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03170506 0,04599494 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03170506 0,04596764 ! gut development GO:0048565 44 22 0,000 0,03170506 0,04594037 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03170506 0,04591314 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,03170506 0,04588594 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03170506 0,04585878 ! protein stabilization GO:0050821 41 22 0,000 0,03170506 0,04583164 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03312253 0,04785236 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03312253 0,04782408 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03312253 0,04779583 ! gluconeogenesis GO:0006094 38 23 0,000 0,03312253 0,04776762 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03312253 0,04773944 ! viral genome replication GO:0019079 44 23 0,000 0,03312253 0,04771129 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03312253 0,04768318 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03312253 0,04765509 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03312253 0,04762704 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03312253 0,04759903 ! regeneration GO:0031099 42 23 0,000 0,03312253 0,04757105 ! axis specification GO:0009798 43 23 0,000 0,03312253 0,0475431 ! visual behavior GO:0007632 46 23 0,000 0,03312253 0,04751518 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,03312253 0,04748729 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,03312253 0,04745944 ! response to ethanol GO:0045471 47 23 0,000 0,03312253 0,04743162 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03312253 0,04740384 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03312253 0,04737608 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03312253 0,04734836 ! peroxisome organization GO:0007031 43 23 0,000 0,03312253 0,04732067 ! lysosome organization GO:0007040 47 23 0,000 0,03312253 0,04729301 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03312253 0,04726539 ! vesicle targeting GO:0006903 49 23 0,000 0,03312253 0,0472378 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03312253 0,04721024 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03312253 0,04718271 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03312253 0,04715521 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03312253 0,04712775 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03312253 0,04710032 ! DNA modification GO:0006304 36 23 0,000 0,03312253 0,04707292 ! fatty acid transport GO:0015908 47 23 0,000 0,03312253 0,04704555 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03312253 0,04701822 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03312253 0,04699091 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03312253 0,04696364 ! hormone transport GO:0009914 41 23 0,000 0,03312253 0,0469364 ! cell-cell recognition GO:0009988 28 23 0,000 0,03312253 0,04690919 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03312253 0,04688201 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03312253 0,04685486 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03312253 0,04682775 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03453797 0,04880061 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03453797 0,0487724 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,03453797 0,04874422 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03453797 0,04871608 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03453797 0,04868797 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03453797 0,04865989 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03453797 0,04863185 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03453797 0,04860383 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03453797 0,04857585 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03453797 0,0485479 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,03453797 0,04851998 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03453797 0,0484921 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03453797 0,04846425 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03453797 0,04843643 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,03453797 0,04840864 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03453797 0,04838088 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03453797 0,04835315 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03453797 0,04832546 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03453797 0,0482978 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,03453797 0,04827017 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03453797 0,04824257 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03453797 0,048215 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03453797 0,04818747 ! membrane depolarization GO:0051899 45 24 0,000 0,03453797 0,04815996 ! pallium development GO:0021543 56 24 0,000 0,03453797 0,04813249 ! oogenesis GO:0048477 44 24 0,000 0,03453797 0,04810505 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03453797 0,04807764 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03453797 0,04805026 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,03453797 0,04802291 ! platelet activation GO:0030168 41 24 0,000 0,03453797 0,04799559 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03453797 0,04796831 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03453797 0,04794105 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03453797 0,04791383 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03453797 0,04788664 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03453797 0,04785947 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03453797 0,04783234 ! regulation of amine transport GO:0051952 41 24 0,000 0,03453797 0,04780524 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,03453797 0,04777817 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03595137 0,04970526 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,03595137 0,04967715 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03595137 0,04964906 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,03595137 0,04962101 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03595137 0,04959299 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03595137 0,04956501 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03595137 0,04953705 ! phototransduction GO:0007602 37 25 0,000 0,03595137 0,04950913 ! keratinization GO:0031424 37 25 0,000 0,03595137 0,04948124 ! vasculogenesis GO:0001570 49 25 0,000 0,03595137 0,04945337 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03595137 0,04942555 ! vacuole organization GO:0007033 49 25 0,000 0,03595137 0,04939775 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03595137 0,04936998 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03595137 0,04934224 ! receptor metabolic process GO:0043112 53 25 0,000 0,03595137 0,04931454 ! chromosome condensation GO:0030261 48 25 0,000 0,03595137 0,04928687 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03595137 0,04925922 ! regulation of behavior GO:0050795 48 25 0,000 0,03595137 0,04923161 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03595137 0,04920403 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03595137 0,04917648 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03595137 0,04914896 ! immunoglobulin production GO:0002377 62 25 0,000 0,03595137 0,04912147 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03595137 0,04909402 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03595137 0,04906659 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03595137 0,04903919 ! liver development GO:0001889 55 25 0,000 0,03595137 0,04901183 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03736274 0,05090752 ! myelination GO:0042552 50 26 0,000 0,03736274 0,05087914 ! initiation of viral infection GO:0019059 60 26 0,000 0,03736274 0,05085079 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03736274 0,05082248 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03736274 0,0507942 ! molting cycle process GO:0022404 52 26 0,000 0,03736274 0,05076595 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03736274 0,05073773 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03736274 0,05070954 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03736274 0,05068139 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03736274 0,05065326 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03736274 0,05062517 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03736274 0,0505971 ! digestive system process GO:0022600 49 26 0,000 0,03736274 0,05056907 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03736274 0,05054107 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03736274 0,0505131 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03736274 0,05048516 ! osteoblast differentiation GO:0001649 63 26 0,000 0,03736274 0,05045726 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,03736274 0,05042938 ! neural crest cell development GO:0014032 59 26 0,000 0,03736274 0,05040153 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03736274 0,05037372 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03736274 0,05034593 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03736274 0,05031818 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03736274 0,05029045 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03736274 0,05026276 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03736274 0,0502351 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03736274 0,05020747 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03736274 0,05017987 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,03736274 0,05015229 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03736274 0,05012475 ! blastocyst development GO:0001824 50 26 0,000 0,03736274 0,05009724 ! telomere organization GO:0032200 46 26 0,000 0,03736274 0,05006976 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03736274 0,05004231 ! neural tube closure GO:0001843 58 26 0,000 0,03736274 0,05001489 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,03736274 0,0499875 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03736274 0,04996014 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03736274 0,04993281 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03877209 0,05178798 ! embryonic pattern specification GO:0009880 49 27 0,000 0,03877209 0,05175968 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03877209 0,05173141 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03877209 0,05170317 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,03877209 0,05167496 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03877209 0,05164679 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03877209 0,05161864 ! iron ion transport GO:0006826 65 27 0,000 0,03877209 0,05159053 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03877209 0,05156244 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03877209 0,05153439 ! tube lumen formation GO:0035148 59 27 0,000 0,03877209 0,05150637 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03877209 0,05147837 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03877209 0,05145041 ! response to starvation GO:0042594 47 27 0,000 0,03877209 0,05142248 ! response to toxin GO:0009636 49 27 0,000 0,03877209 0,05139458 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03877209 0,05136671 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03877209 0,05133887 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03877209 0,05131105 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03877209 0,05128327 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03877209 0,05125552 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03877209 0,0512278 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,04017941 0,05305854 ! neuron fate commitment GO:0048663 52 28 0,000 0,04017941 0,05302987 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,04017941 0,05300124 ! protein amino acid acylation GO:0043543 59 28 0,000 0,04017941 0,05297264 ! vesicle docking GO:0048278 55 28 0,000 0,04017941 0,05294406 ! circadian rhythm GO:0007623 56 28 0,000 0,04017941 0,05291552 ! dendrite development GO:0016358 67 28 0,000 0,04017941 0,05288701 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,04017941 0,05285853 ! fat cell differentiation GO:0045444 57 28 0,000 0,04017941 0,05283008 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,04017941 0,05280166 ! sperm motility GO:0030317 37 28 0,000 0,04017941 0,05277328 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,04017941 0,05274492 ! base-excision repair GO:0006284 41 28 0,000 0,04017941 0,05271659 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,04017941 0,0526883 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,04017941 0,05266003 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,04017941 0,05263179 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,04017941 0,05260359 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,04017941 0,05257541 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,04017941 0,05254727 ! glutathione metabolic process GO:0006749 42 28 0,000 0,04017941 0,05251915 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,04017941 0,05249107 ! lipid oxidation GO:0034440 48 28 0,000 0,04017941 0,05246301 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,04017941 0,05243499 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,04017941 0,05240699 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,04158471 0,05421102 ! translational initiation GO:0006413 66 29 0,000 0,04158471 0,0541821 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,04158471 0,05415322 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,04158471 0,05412437 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,04158471 0,05409555 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,04158471 0,05406676 ! autophagy GO:0006914 47 29 0,000 0,04158471 0,054038 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,04158471 0,05400927 ! primary neural tube formation GO:0014020 61 29 0,000 0,04158471 0,05398058 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,04158471 0,05395191 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,04158471 0,05392327 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,04158471 0,05389467 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,04158471 0,05386609 ! somitogenesis GO:0001756 52 29 0,000 0,04158471 0,05383754 ! synaptogenesis GO:0007416 46 29 0,000 0,04158471 0,05380903 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,04158471 0,05378054 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,04158471 0,05375209 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,04158471 0,05372366 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,04158471 0,05369527 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,04298799 0,0554779 ! phenol metabolic process GO:0018958 56 30 0,000 0,04298799 0,05544861 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,04298799 0,05541935 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,04298799 0,05539012 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,04298799 0,05536092 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,04298799 0,05533175 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,04298799 0,05530261 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,04298799 0,05527351 ! acute-phase response GO:0006953 50 30 0,000 0,04298799 0,05524443 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,04298799 0,05521539 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,04298799 0,05518637 ! myofibril assembly GO:0030239 50 30 0,000 0,04298799 0,05515739 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,04298799 0,05512843 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,04298799 0,05509951 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,04298799 0,05507062 ! cell fate determination GO:0001709 64 30 0,000 0,04298799 0,05504175 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,04298799 0,05501292 ! phospholipid transport GO:0015914 65 30 0,000 0,04298799 0,05498412 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,04298799 0,05495535 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,04298799 0,0549266 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,04298799 0,05489789 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,04298799 0,05486921 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,04298799 0,05484056 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,04298799 0,05481193 ! regulation of coagulation GO:0050818 52 30 0,000 0,04298799 0,05478334 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04438926 0,05653961 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04438926 0,05651014 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04438926 0,05648071 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04438926 0,05645131 ! cell junction assembly GO:0034329 85 31 0,000 0,04438926 0,05642194 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04438926 0,0563926 ! ovulation cycle process GO:0022602 55 31 0,000 0,04438926 0,05636329 ! peptide transport GO:0015833 60 31 0,000 0,04438926 0,05633401 ! male gonad development GO:0008584 56 31 0,000 0,04438926 0,05630476 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04438926 0,05627554 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,04438926 0,05624635 ! detection of light stimulus GO:0009583 44 31 0,000 0,04438926 0,05621719 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,04438926 0,05618806 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,04438926 0,05615897 ! natural killer cell activation GO:0030101 50 31 0,000 0,04438926 0,0561299 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04438926 0,05610086 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04438926 0,05607185 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04438926 0,05604287 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04438926 0,05601393 ! eye morphogenesis GO:0048592 65 31 0,000 0,04438926 0,05598501 ! response to heat GO:0009408 54 31 0,000 0,04438926 0,05595612 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04438926 0,05592726 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,04578852 0,05766049 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,04578852 0,05763078 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,04578852 0,0576011 ! spindle organization GO:0007051 50 32 0,000 0,04578852 0,05757146 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,04578852 0,05754184 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,04578852 0,05751226 ! metanephros development GO:0001656 81 32 0,000 0,04578852 0,0574827 ! muscle cell development GO:0055001 52 32 0,000 0,04578852 0,05745318 ! mesoderm formation GO:0001707 73 32 0,000 0,04578852 0,05742369 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,04578852 0,05739422 ! ovulation cycle GO:0042698 57 32 0,000 0,04578852 0,05736479 ! peripheral nervous system development GO:0007422 68 32 0,000 0,04578852 0,05733539 ! BMP signaling pathway GO:0030509 71 32 0,000 0,04578852 0,05730602 ! hindbrain development GO:0030902 65 32 0,000 0,04578852 0,05727667 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,04578852 0,05724736 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,04578852 0,05721808 ! gene silencing GO:0016458 71 32 0,000 0,04578852 0,05718883 ! regulation of pH GO:0006885 56 33 0,000 0,04718576 0,05890384 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,04718576 0,05887376 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,04718576 0,0588437 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,04718576 0,05881368 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,04718576 0,05878369 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,04718576 0,05875373 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,04718576 0,0587238 ! response to ionizing radiation GO:0010212 74 33 0,000 0,04718576 0,0586939 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,04718576 0,05866403 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,04718576 0,05863419 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,04718576 0,05860438 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,04718576 0,0585746 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,04718576 0,05854485 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,04718576 0,05851513 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,04718576 0,05848545 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,048581 0,06018427 ! glial cell differentiation GO:0010001 67 34 0,000 0,048581 0,06015377 ! post-embryonic development GO:0009791 76 34 0,000 0,048581 0,0601233 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,048581 0,06009285 ! cholesterol transport GO:0030301 62 34 0,000 0,048581 0,06006244 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,048581 0,06003206 ! spliceosome assembly GO:0000245 75 34 0,000 0,048581 0,06000171 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,048581 0,05997139 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,048581 0,0599411 ! formation of primary germ layer GO:0001704 76 34 0,000 0,048581 0,05991085 ! cell fate specification GO:0001708 56 34 0,000 0,048581 0,05988062 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,048581 0,05985042 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,048581 0,05982025 ! adult locomotory behavior GO:0008344 62 34 0,000 0,048581 0,05979012 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04997424 0,06147385 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04997424 0,06144291 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04997424 0,061412 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04997424 0,06138113 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,04997424 0,06135028 ! membrane docking GO:0022406 69 35 0,000 0,04997424 0,06131947 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,04997424 0,06128868 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04997424 0,06125793 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04997424 0,06122721 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04997424 0,06119652 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04997424 0,06116586 ! telencephalon development GO:0021537 81 35 0,000 0,04997424 0,06113523 ! sterol transport GO:0015918 63 35 0,000 0,04997424 0,06110463 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,04997424 0,06107407 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04997424 0,06104353 ! placenta development GO:0001890 53 35 0,000 0,04997424 0,06101302 ! vesicle localization GO:0051648 70 35 0,000 0,04997424 0,06098255 ! regulation of muscle development GO:0048634 82 36 0,000 0,05136547 0,06264895 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,05136547 0,06261769 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,05136547 0,06258646 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,05136547 0,06255526 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,05136547 0,06252409 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,05136547 0,06249295 ! positive regulation of cell development GO:0010720 85 36 0,000 0,05136547 0,06246184 ! protein targeting to membrane GO:0006612 75 36 0,000 0,05136547 0,06243077 ! regulation of proteolysis GO:0030162 77 36 0,000 0,05136547 0,06239972 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,05136547 0,06236871 ! aerobic respiration GO:0009060 56 36 0,000 0,05136547 0,06233773 ! cytokine production GO:0001816 68 36 0,000 0,05136547 0,06230677 ! embryonic organ development GO:0048568 67 36 0,000 0,05136547 0,06227585 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,05136547 0,06224496 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,05136547 0,0622141 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,05275471 0,06386509 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,05275471 0,06383346 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,05275471 0,06380186 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,05275471 0,06377029 ! sister chromatid segregation GO:0000819 65 37 0,000 0,05275471 0,06373875 ! odontogenesis GO:0042476 74 37 0,000 0,05275471 0,06370724 ! actomyosin structure organization GO:0031032 68 37 0,000 0,05275471 0,06367576 ! cell junction organization GO:0034330 96 37 0,000 0,05275471 0,06364432 ! tissue remodeling GO:0048771 78 37 0,000 0,05275471 0,06361291 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,05275471 0,06358152 ! female gonad development GO:0008585 71 37 0,000 0,05275471 0,06355017 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,05275471 0,06351885 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,05275471 0,06348756 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,05275471 0,0634563 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,05275471 0,06342507 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,05414195 0,06506088 ! meiosis I GO:0007127 74 38 0,000 0,05414195 0,0650289 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,05414195 0,06499694 ! organic anion transport GO:0015711 82 38 0,000 0,05414195 0,06496502 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,05414195 0,06493313 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,05414195 0,06490126 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,05414195 0,06486943 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,05414195 0,06483764 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,05414195 0,06480587 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,05414195 0,06477413 ! regulation of protein stability GO:0031647 77 38 0,000 0,05414195 0,06474243 ! spermatid development GO:0007286 69 38 0,000 0,05414195 0,06471075 ! glycogen metabolic process GO:0005977 63 38 0,000 0,05414195 0,06467911 ! pigment metabolic process GO:0042440 87 38 0,000 0,05414195 0,0646475 ! neural tube formation GO:0001841 79 38 0,000 0,05414195 0,06461591 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,0555272 0,06623679 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,0555272 0,06620446 ! negative regulation of binding GO:0051100 71 39 0,000 0,0555272 0,06617216 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,0555272 0,0661399 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,0555272 0,06610767 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,0555272 0,06607547 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,0555272 0,0660433 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,0555272 0,06601116 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,0555272 0,06597906 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,0555272 0,06594698 ! glucan metabolic process GO:0044042 64 39 0,000 0,0555272 0,06591494 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,05691045 0,06752416 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,05691045 0,06749138 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,05691045 0,06745863 ! learning GO:0007612 82 40 0,000 0,05691045 0,06742592 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,05691045 0,06739323 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,05691045 0,06736058 ! lipid homeostasis GO:0055088 75 40 0,000 0,05691045 0,06732796 ! mismatch repair GO:0006298 58 40 0,000 0,05691045 0,06729537 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,05691045 0,06726281 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,05691045 0,06723029 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,05691045 0,0671978 ! RNA export from nucleus GO:0006405 61 41 0,000 0,05829172 0,0687955 ! mRNA catabolic process GO:0006402 79 41 0,000 0,05829172 0,06876228 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,05829172 0,06872909 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,05829172 0,06869594 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,05829172 0,06866282 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,05829172 0,06862973 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,05829172 0,06859667 ! gliogenesis GO:0042063 91 41 0,000 0,05829172 0,06856364 ! feeding behavior GO:0007631 69 41 0,000 0,05829172 0,06853065 ! mesenchymal cell development GO:0014031 94 41 0,000 0,05829172 0,06849768 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,05829172 0,06846475 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,05829172 0,06843185 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,05829172 0,06839898 ! spermatid differentiation GO:0048515 73 41 0,000 0,05829172 0,06836615 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,05829172 0,06833334 ! RNA modification GO:0009451 64 41 0,000 0,05829172 0,06830057 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,05967101 0,06988317 ! ear morphogenesis GO:0042471 64 42 0,000 0,05967101 0,06984968 ! organic ether metabolic process GO:0018904 59 42 0,000 0,05967101 0,06981623 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,05967101 0,06978281 ! T cell differentiation GO:0030217 93 42 0,000 0,05967101 0,06974942 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05967101 0,06971606 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05967101 0,06968274 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05967101 0,06964944 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,05967101 0,06961618 ! cytokinesis GO:0000910 84 42 0,000 0,05967101 0,06958295 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05967101 0,06954975 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,06104832 0,07112114 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,06104832 0,07108725 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,06104832 0,07105338 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,06104832 0,07101954 ! regulation of tube size GO:0035150 76 43 0,000 0,06104832 0,07098574 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,06104832 0,07095197 ! glucose transport GO:0015758 66 43 0,000 0,06104832 0,07091823 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,06104832 0,07088452 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,06104832 0,07085085 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,06104832 0,07081721 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,06104832 0,0707836 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,06104832 0,07075002 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,06104832 0,07071647 ! segmentation GO:0035282 78 43 0,000 0,06104832 0,07068296 ! ion transmembrane transport GO:0034220 79 43 0,000 0,06104832 0,07064947 ! neuron migration GO:0001764 85 43 0,000 0,06104832 0,07061602 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,06104832 0,0705826 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,06242364 0,07213858 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,06242364 0,07210447 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,06242364 0,0720704 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,06242364 0,07203636 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,06242364 0,07200234 ! hexose transport GO:0008645 68 44 0,000 0,06242364 0,07196836 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,06242364 0,07193442 ! striated muscle contraction GO:0006941 85 44 0,000 0,06242364 0,0719005 ! phagocytosis GO:0006909 105 44 0,000 0,06242364 0,07186662 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,06242364 0,07183277 ! double-strand break repair GO:0006302 85 44 0,000 0,06242364 0,07179895 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,063797 0,07334403 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,063797 0,07330953 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,063797 0,07327506 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,063797 0,07324063 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,063797 0,07320623 ! biopolymer methylation GO:0043414 91 45 0,000 0,063797 0,07317186 ! B cell differentiation GO:0030183 124 45 0,000 0,063797 0,07313752 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,063797 0,07310322 ! female gamete generation GO:0007292 71 45 0,000 0,063797 0,07306895 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,063797 0,07303471 ! polyol metabolic process GO:0019751 77 45 0,000 0,063797 0,0730005 ! developmental growth GO:0048589 88 45 0,000 0,063797 0,07296632 ! maintenance of location in cell GO:0051651 101 45 0,000 0,063797 0,07293218 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,06516837 0,07446508 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,06516837 0,07443027 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,06516837 0,07439549 ! glycolysis GO:0006096 71 46 0,000 0,06516837 0,07436074 ! leukocyte migration GO:0050900 75 46 0,000 0,06516837 0,07432602 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,06516837 0,07429134 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,06516837 0,07425669 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,06516837 0,07422207 ! pigmentation GO:0043473 103 46 0,000 0,06516837 0,07418748 ! cell growth GO:0016049 90 46 0,000 0,06516837 0,07415293 ! neural tube development GO:0021915 91 47 0,000 0,06653778 0,07567589 ! positive regulation of defense response GO:0031349 88 48 0,000 0,06790522 0,07719519 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,06790522 0,07715928 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,06790522 0,07712341 ! cellular component disassembly GO:0022411 89 48 0,000 0,06790522 0,07708757 ! endosome transport GO:0016197 127 48 0,000 0,06790522 0,07705177 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,06790522 0,077016 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,06790522 0,07698026 ! male sex differentiation GO:0046661 93 48 0,000 0,06790522 0,07694455 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,06790522 0,07690888 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,06790522 0,07687324 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,06790522 0,07683764 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,06790522 0,07680206 ! methylation GO:0032259 97 48 0,000 0,06790522 0,07676652 ! response to calcium ion GO:0051592 94 49 0,000 0,0692707 0,07827397 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,0692707 0,07823778 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,0692707 0,07820163 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,0692707 0,0781655 ! JNK cascade GO:0007254 106 49 0,000 0,0692707 0,07812942 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,0692707 0,07809336 ! regulation of action potential GO:0001508 102 50 0,000 0,07063421 0,07959381 ! regulation of ion transport GO:0043269 86 50 0,000 0,07063421 0,07955711 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,07063421 0,07952045 ! endocrine system development GO:0035270 109 50 0,000 0,07063421 0,07948382 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,07063421 0,07944723 ! activation of caspase activity GO:0006919 95 50 0,000 0,07063421 0,07941067 ! regulation of ossification GO:0030278 123 50 0,000 0,07063421 0,07937414 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,07063421 0,07933765 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,07063421 0,07930119 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,07063421 0,07926476 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,07063421 0,07922837 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,07199577 0,08071852 ! viral infectious cycle GO:0019058 104 51 0,000 0,07199577 0,08068149 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,07199577 0,0806445 ! peptide metabolic process GO:0006518 80 51 0,000 0,07199577 0,08060754 ! response to temperature stimulus GO:0009266 84 51 0,000 0,07199577 0,08057062 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,07199577 0,08053373 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,07199577 0,08049687 ! positive regulation of binding GO:0051099 88 52 0,000 0,07335537 0,08197949 ! Notch signaling pathway GO:0007219 111 52 0,000 0,07335537 0,081942 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,07335537 0,08190455 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,07335537 0,08186713 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,07335537 0,08182975 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,07335537 0,0817924 ! excretion GO:0007588 87 52 0,000 0,07335537 0,08175509 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,07335537 0,08171781 ! histone modification GO:0016570 104 52 0,000 0,07335537 0,08168056 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,07335537 0,08164335 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,07335537 0,08160617 ! amino acid activation GO:0043038 98 52 0,000 0,07335537 0,08156903 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,07471301 0,08304089 ! inner ear development GO:0048839 89 53 0,000 0,07471301 0,08300313 ! chromatin remodeling GO:0006338 122 53 0,000 0,07471301 0,0829654 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,07471301 0,08292771 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,07471301 0,08289005 ! vesicle organization GO:0016050 127 53 0,000 0,07471301 0,08285242 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,07471301 0,08281483 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,07471301 0,08277727 ! synapse organization GO:0050808 102 53 0,000 0,07471301 0,08273975 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,0760687 0,08420292 ! regulation of translational initiation GO:0006446 87 54 0,000 0,0760687 0,08416478 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,0760687 0,08412668 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,0760687 0,08408862 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,0760687 0,08405058 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,0760687 0,08401259 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,0760687 0,08397462 ! membrane fusion GO:0006944 122 54 0,000 0,0760687 0,0839367 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,0760687 0,0838988 ! covalent chromatin modification GO:0016569 115 54 0,000 0,0760687 0,08386094 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,0760687 0,08382311 ! regulation of cell shape GO:0008360 142 54 0,000 0,0760687 0,08378532 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,0760687 0,08374756 ! RNA catabolic process GO:0006401 103 55 0,000 0,07742245 0,08519957 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,07742245 0,08516121 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,07742245 0,08512288 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,07742245 0,08508459 ! cell recognition GO:0008037 98 55 0,000 0,07742245 0,08504633 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,07742245 0,08500811 ! cell maturation GO:0048469 107 55 0,000 0,07742245 0,08496992 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,07742245 0,08493177 ! response to UV GO:0009411 120 55 0,000 0,07742245 0,08489365 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,07742245 0,08485556 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,07877425 0,08629843 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,07877425 0,08625974 ! glucose catabolic process GO:0006007 88 56 0,000 0,07877425 0,0862211 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,07877425 0,08618249 ! RNA elongation GO:0006354 90 56 0,000 0,07877425 0,08614391 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,08012411 0,08758085 ! chloride transport GO:0006821 102 57 0,000 0,08012411 0,08754168 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,08012411 0,08750254 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,08012411 0,08746345 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,08012411 0,08742438 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,08012411 0,08738535 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,08012411 0,08734636 ! regulation of actin filament length GO:0030832 118 58 0,000 0,08147202 0,08877616 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,08147202 0,08873658 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,08147202 0,08869704 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,08147202 0,08865753 ! aging GO:0007568 112 58 0,000 0,08147202 0,08861806 ! gastrulation GO:0007369 122 58 0,000 0,08147202 0,08857862 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,08147202 0,08853921 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,08147202 0,08849985 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,08147202 0,08846051 ! maintenance of location GO:0051235 124 58 0,000 0,08147202 0,08842121 ! nuclear export GO:0051168 110 59 0,000 0,082818 0,08984209 ! establishment of organelle localization GO:0051656 122 59 0,000 0,082818 0,08980221 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,08416205 0,09121912 ! DNA catabolic process GO:0006308 94 60 0,000 0,08416205 0,09117866 ! regulation of endocytosis GO:0030100 104 60 0,000 0,08416205 0,09113825 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,08416205 0,09109787 ! adult behavior GO:0030534 104 60 0,000 0,08416205 0,09105752 ! kidney development GO:0001822 133 60 0,000 0,08416205 0,09101721 ! positive regulation of secretion GO:0051047 110 61 0,000 0,08550416 0,09242773 ! regulation of cellular component size GO:0032535 125 61 0,000 0,08550416 0,09238685 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,08550416 0,09234601 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,08550416 0,0923052 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,08550416 0,09226443 ! regulation of heart contraction GO:0008016 123 61 0,000 0,08550416 0,0922237 ! camera-type eye development GO:0043010 126 61 0,000 0,08550416 0,092183 ! proton transport GO:0015992 117 61 0,000 0,08550416 0,09214233 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,08550416 0,09210171 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,08684435 0,09350407 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,08684435 0,09346288 ! tRNA processing GO:0008033 102 62 0,000 0,08684435 0,09342173 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,08684435 0,09338061 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,08818261 0,09477788 ! mesoderm development GO:0007498 128 63 0,000 0,08818261 0,0947362 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,08818261 0,09469455 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,08818261 0,09465295 ! hydrogen transport GO:0006818 121 64 0,000 0,08951894 0,09604514 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,08951894 0,09600297 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,08951894 0,09596085 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,09085336 0,09734857 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,09085336 0,0973059 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,09085336 0,09726326 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,09085336 0,09722065 ! ear development GO:0043583 114 66 0,000 0,09218585 0,09860334 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,09218585 0,09856019 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,09218585 0,09851708 ! gonad development GO:0008406 115 66 0,000 0,09218585 0,098474 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,09218585 0,09843096 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,09351643 0,09980806 ! chromosome segregation GO:0007059 127 67 0,000 0,09351643 0,09976447 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,09351643 0,09972093 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,09351643 0,09967742 ! secondary metabolic process GO:0019748 125 67 0,000 0,09351643 0,09963395 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,09351643 0,09959052 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,0948451 0,10096147 ! hexose catabolic process GO:0019320 113 68 0,000 0,0948451 0,1009175 ! extracellular matrix organization GO:0030198 146 68 0,000 0,0948451 0,10087357 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,0948451 0,10082967 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,0948451 0,10078581 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,0948451 0,10074199 ! regulation of lipase activity GO:0060191 137 68 0,000 0,0948451 0,10069821 ! adaptive immune response GO:0002250 126 68 0,000 0,0948451 0,10065447 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,0948451 0,10061076 ! cell projection assembly GO:0030031 138 68 0,000 0,0948451 0,10056709 ! negative regulation of cell size GO:0045792 144 69 0,000 0,09617186 0,10192965 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,09617186 0,10188545 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,09617186 0,10184129 ! lung development GO:0030324 165 69 0,000 0,09617186 0,10179716 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,09617186 0,10175308 ! urogenital system development GO:0001655 149 69 0,000 0,09617186 0,10170903 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,09617186 0,10166502 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,09617186 0,10162104 ! single fertilization GO:0007338 83 69 0,000 0,09617186 0,10157711 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,09749671 0,10293192 ! cell redox homeostasis GO:0045454 114 70 0,000 0,09749671 0,10288746 ! germ cell development GO:0007281 133 70 0,000 0,09749671 0,10284303 ! activation of immune response GO:0002253 120 70 0,000 0,09749671 0,10279864 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,09749671 0,1027543 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,09881965 0,10410367 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,09881965 0,1040588 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,09881965 0,10401397 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,09881965 0,10396917 ! carbohydrate transport GO:0008643 114 72 0,000 0,1001407 0,1053137 ! respiratory tube development GO:0030323 171 72 0,000 0,1001407 0,10526838 ! actin filament organization GO:0007015 167 72 0,000 0,1001407 0,10522311 ! B cell activation GO:0042113 179 72 0,000 0,1001407 0,10517787 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,1001407 0,10513267 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,1001407 0,10508751 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,1001407 0,10504239 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,1001407 0,10499731 ! humoral immune response GO:0006959 115 73 0,000 0,10145984 0,10633479 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,10145984 0,10628919 ! regulation of immune effector process GO:0002697 156 73 0,000 0,10145984 0,10624363 ! acute inflammatory response GO:0002526 118 74 0,000 0,10277709 0,10757688 ! amino acid transport GO:0006865 148 74 0,000 0,10277709 0,10753081 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,10277709 0,10748477 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,10277709 0,10743878 ! respiratory system development GO:0060541 175 74 0,000 0,10277709 0,10739283 ! organelle localization GO:0051640 155 74 0,000 0,10277709 0,10734691 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,10409244 0,10867429 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,10409244 0,10862787 ! reproductive structure development GO:0048608 131 75 0,000 0,10409244 0,10858149 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,10409244 0,10853514 ! eye development GO:0001654 155 75 0,000 0,10409244 0,10848884 ! axon guidance GO:0007411 162 75 0,000 0,10409244 0,10844258 ! rhythmic process GO:0048511 142 75 0,000 0,10409244 0,10839635 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,10540591 0,10971735 ! learning or memory GO:0007611 161 76 0,000 0,10540591 0,10967063 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,10540591 0,10962394 ! regulation of blood pressure GO:0008217 134 76 0,000 0,10540591 0,10957729 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,10540591 0,10953068 ! amine catabolic process GO:0009310 136 77 0,000 0,10671748 0,11084643 ! neurotransmitter transport GO:0006836 142 77 0,000 0,10671748 0,11079932 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,10671748 0,11075225 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,10671748 0,11070522 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,10671748 0,11065824 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,10671748 0,11061129 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,10802717 0,11192128 ! antigen processing and presentation GO:0019882 117 78 0,000 0,10802717 0,11187383 ! fertilization GO:0009566 99 78 0,000 0,10802717 0,11182643 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,10802717 0,11177906 ! blood coagulation GO:0007596 151 79 0,000 0,10933497 0,11308439 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,10933497 0,11303654 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,10933497 0,11298872 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,10933497 0,11294094 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,10933497 0,11289321 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,11064089 0,11419337 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,11064089 0,11414515 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,11064089 0,11409696 ! meiosis GO:0007126 143 81 0,000 0,11194494 0,11539303 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,11194494 0,11534437 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,11194494 0,11529574 ! protein import into nucleus GO:0006606 174 82 0,000 0,11324711 0,11658773 ! meiotic cell cycle GO:0051321 144 82 0,000 0,11324711 0,11653862 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,11454741 0,11782708 ! exocytosis GO:0006887 153 83 0,000 0,11454741 0,11777749 ! response to drug GO:0042493 149 83 0,000 0,11454741 0,11772794 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,11454741 0,11767843 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,11454741 0,11762897 ! nuclear import GO:0051170 177 83 0,000 0,11454741 0,11757955 ! inorganic anion transport GO:0015698 156 83 0,000 0,11454741 0,11753016 ! response to metal ion GO:0010038 158 84 0,000 0,11584584 0,1188125 ! T cell activation GO:0042110 189 84 0,000 0,11584584 0,11876264 ! response to nutrient GO:0007584 135 84 0,000 0,11584584 0,11871283 ! digestion GO:0007586 130 84 0,000 0,11584584 0,11866305 ! regulation of ligase activity GO:0051340 147 84 0,000 0,11584584 0,11861332 ! hemostasis GO:0007599 165 85 0,000 0,1171424 0,1198906 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,1171424 0,1198404 ! negative regulation of growth GO:0045926 168 85 0,000 0,1171424 0,11979024 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,1171424 0,11974011 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,1171424 0,11969003 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,1171424 0,11964 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,11843709 0,12091175 ! regulation of lyase activity GO:0051339 169 86 0,000 0,11843709 0,12086124 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,11843709 0,12081078 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,11972992 0,12207855 ! alcohol catabolic process GO:0046164 142 87 0,000 0,11972992 0,12202762 ! nucleosome assembly GO:0006334 126 87 0,000 0,11972992 0,12197673 ! cellular respiration GO:0045333 143 88 0,000 0,1210209 0,12324054 ! amine biosynthetic process GO:0009309 146 88 0,000 0,1210209 0,12318919 ! sensory perception of smell GO:0007608 117 88 0,000 0,1210209 0,12313788 ! chromatin assembly GO:0031497 128 88 0,000 0,1210209 0,12308662 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,1210209 0,12303539 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,12231001 0,12429424 ! regulation of DNA binding GO:0051101 167 89 0,000 0,12231001 0,12424256 ! cellular defense response GO:0006968 123 89 0,000 0,12231001 0,12419092 ! protein localization in nucleus GO:0034504 192 89 0,000 0,12231001 0,12413933 ! regulation of neurological system process GO:0031644 175 89 0,000 0,12231001 0,12408778 ! response to inorganic substance GO:0010035 173 90 0,000 0,12359728 0,1253417 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,12359728 0,12528969 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,12359728 0,12523772 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,12488269 0,12648773 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,12488269 0,12643531 ! defense response to bacterium GO:0042742 112 91 0,000 0,12488269 0,12638293 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,12616625 0,12762904 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,12616625 0,12757622 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,12744796 0,12881894 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,12744796 0,12876566 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,12744796 0,12871243 ! vitamin metabolic process GO:0006766 153 93 0,000 0,12744796 0,12865924 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,12872783 0,1298976 ! sterol metabolic process GO:0016125 166 94 0,000 0,12872783 0,12984397 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,12872783 0,12979038 ! regulation of membrane potential GO:0042391 179 94 0,000 0,12872783 0,12973684 ! regulation of defense response GO:0031347 171 95 0,000 0,13000586 0,13097086 ! nucleosome organization GO:0034728 143 95 0,000 0,13000586 0,13091687 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,13000586 0,13086293 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,13000586 0,13080903 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,13000586 0,13075518 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,13000586 0,13070137 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,13000586 0,1306476 ! sex differentiation GO:0007548 171 96 0,000 0,13128205 0,13187585 ! regulation of T cell activation GO:0050863 175 96 0,000 0,13128205 0,13182164 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,13255641 0,13304655 ! transcription initiation GO:0006352 171 97 0,000 0,13255641 0,13299191 ! leukocyte differentiation GO:0002521 232 98 0,000 0,13382893 0,1342135 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,13382893 0,13415842 ! forebrain development GO:0030900 210 98 0,000 0,13382893 0,1341034 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,13382893 0,13404841 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,13636848 0,13653615 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,13636848 0,13648021 ! positive regulation of immune response GO:0050778 175 100 0,000 0,13636848 0,13642433 ! hormone metabolic process GO:0042445 171 100 0,000 0,13636848 0,13636848