pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/793-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of DNA metabolic process GO:0051052 188 97 5,000 1,919E-08 4,688E-05 ! nuclear migration GO:0007097 13 6 2,000 1,007E-07 1,23E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 1,007E-07 8,2E-05 GO:0031272|regulation of pseudopodium assembly, ! interaction with host GO:0051701 66 25 3,000 1,033E-07 6,306E-05 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,429E-07 6,981E-05 ! negative regulation of telomere maintenance GO:0032205 13 7 2,000 1,76E-07 7,166E-05 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 2,813E-07 9,816E-05 ! establishment of nucleus localization GO:0040023 18 8 2,000 2,813E-07 8,589E-05 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 3,000 3,741E-07 1,016E-04 ! regulation of telomere maintenance GO:0032204 17 9 2,000 4,214E-07 1,029E-04 ! macrophage differentiation GO:0030225 15 9 2,000 4,214E-07 9,358E-05 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 5,924E-07 1,206E-04 ! regulation of sodium ion transport GO:0002028 26 10 2,000 6,012E-07 1,13E-04 ! telomere maintenance via telomerase GO:0007004 24 11 2,000 8,256E-07 1,441E-04 GO:0010833|telomere maintenance via telomere lengthening, ! nucleus localization GO:0051647 22 11 2,000 8,256E-07 1,345E-04 ! regulation of cell projection assembly GO:0060491 33 12 2,000 1,099E-06 1,679E-04 ! response to insulin stimulus GO:0032868 98 47 3,000 1,415E-06 2,033E-04 ! RNA-dependent DNA replication GO:0006278 28 14 2,000 1,815E-06 2,463E-04 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 2,000 2,785E-06 3,58E-04 ! filopodium assembly GO:0046847 42 17 2,000 3,377E-06 4,125E-04 ! negative regulation of homeostatic process GO:0032845 36 17 2,000 3,377E-06 3,929E-04 ! establishment of organelle localization GO:0051656 122 59 3,000 3,554E-06 3,946E-04 ! microspike assembly GO:0030035 46 18 2,000 4,048E-06 4,299E-04 ! viral reproductive process GO:0022415 132 62 3,000 4,339E-06 4,417E-04 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 4,929E-06 4,817E-04 ! viral reproduction GO:0016032 142 68 3,000 6,285E-06 5,905E-04 ! regulation of DNA recombination GO:0000018 51 23 2,000 8,73E-06 7,899E-04 ! organelle localization GO:0051640 155 74 3,000 8,81E-06 7,687E-04 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 1,131E-05 9,527E-04 ! negative regulation of organelle organization GO:0010639 181 80 3,000 1,202E-05 9,785E-04 ! telomere organization GO:0032200 46 26 2,000 1,277E-05 1,006E-03 GO:0000723|telomere maintenance, ! positive regulation of cell projection organization GO:0031346 66 27 2,000 1,435E-05 1,095E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 1,435E-05 1,062E-03 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,528E-05 1,098E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 1,984E-05 1,385E-03 ! positive regulation of catabolic process GO:0009896 72 32 2,000 2,418E-05 1,641E-03 ! leukocyte differentiation GO:0002521 232 98 3,000 2,681E-05 1,77E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,984E-05 1,918E-03 ! valine metabolic process GO:0006573 12 5 1,000 2,984E-05 1,869E-03 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 2,984E-05 1,822E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! metaphase plate congression GO:0051310 7 5 1,000 2,984E-05 1,778E-03 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 3,179E-05 1,849E-03 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 4,082E-05 2,319E-03 ! regulation of metal ion transport GO:0010959 71 39 2,000 4,416E-05 2,452E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 4,47E-05 2,427E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! protein targeting to lysosome GO:0006622 12 6 1,000 4,47E-05 2,374E-03 ! G2 phase GO:0051319 16 6 1,000 4,47E-05 2,324E-03 GO:0000085|G2 phase of mitotic cell cycle, ! receptor internalization GO:0031623 11 6 1,000 4,47E-05 2,275E-03 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 1,000 4,47E-05 2,229E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 5,138E-05 2,511E-03 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 6,251E-05 2,995E-03 GO:0031958|corticosteroid receptor signaling pathway, ! male sex determination GO:0030238 15 7 1,000 6,251E-05 2,937E-03 ! spindle checkpoint GO:0031577 16 7 1,000 6,251E-05 2,882E-03 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 6,251E-05 2,828E-03 ! negative regulation of nuclear division GO:0051784 15 7 1,000 6,251E-05 2,777E-03 GO:0045839|negative regulation of mitosis, ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 6,251E-05 2,727E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 1,000 8,326E-05 3,568E-03 ! protein targeting to vacuole GO:0006623 14 8 1,000 8,326E-05 3,507E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 8,326E-05 3,447E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 8,326E-05 3,39E-03 ! establishment of chromosome localization GO:0051303 14 8 1,000 8,326E-05 3,334E-03 GO:0050000|chromosome localization, ! regulation of respiratory burst GO:0060263 12 8 1,000 8,326E-05 3,281E-03 ! lymph node development GO:0048535 11 8 1,000 8,326E-05 3,229E-03 ! regulation of Rac protein signal transduction GO:0035020 18 8 1,000 8,326E-05 3,178E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 1,000 8,326E-05 3,129E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 8,326E-05 3,082E-03 ! regulation of ion transport GO:0043269 86 50 2,000 9,343E-05 3,407E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 9,914E-05 3,562E-03 ! negative regulation of immune system process GO:0002683 101 51 2,000 9,914E-05 3,51E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,069E-04 3,732E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 1,069E-04 3,679E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,069E-04 3,628E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 1,069E-04 3,578E-03 GO:0002820|negative regulation of adaptive immune response, ! pyrimidine base metabolic process GO:0006206 22 9 1,000 1,069E-04 3,53E-03 ! regulation of DNA replication GO:0006275 105 56 2,000 1,312E-04 4,272E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 1,335E-04 4,292E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,335E-04 4,236E-03 ! pathogenesis GO:0009405 17 10 1,000 1,335E-04 4,181E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 1,335E-04 4,129E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,335E-04 4,077E-03 GO:0043470|regulation of carbohydrate catabolic process, ! negative regulation of immune effector process GO:0002698 23 10 1,000 1,335E-04 4,027E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 1,63E-04 4,856E-03 ! regulation of homeostatic process GO:0032844 148 62 2,000 1,776E-04 5,228E-03 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,863E-04 5,417E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,954E-04 5,615E-03 ! virus-host interaction GO:0019048 30 12 1,000 1,954E-04 5,55E-03 ! focal adhesion formation GO:0048041 37 12 1,000 1,954E-04 5,486E-03 ! entry into host cell GO:0030260 34 12 1,000 1,954E-04 5,424E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of lipid metabolic process GO:0019216 132 66 2,000 2,138E-04 5,87E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 2,138E-04 5,804E-03 ! myeloid cell differentiation GO:0030099 126 67 2,000 2,236E-04 6,002E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 2,306E-04 6,124E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,306E-04 6,058E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of homeostatic process GO:0032846 23 13 1,000 2,306E-04 5,994E-03 ! cell projection assembly GO:0030031 138 68 2,000 2,336E-04 6,007E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 2,654E-04 6,755E-03 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 1,000 2,688E-04 6,769E-03 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 3,098E-04 7,722E-03 ! regulation of catabolic process GO:0009894 173 77 2,000 3,372E-04 8,321E-03 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,536E-04 8,639E-03 ! lysosomal transport GO:0007041 31 16 1,000 3,536E-04 8,553E-03 ! negative regulation of immune response GO:0050777 38 16 1,000 3,536E-04 8,47E-03 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 4,003E-04 9,495E-03 ! nucleobase metabolic process GO:0009112 43 17 1,000 4,003E-04 9,404E-03 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 4,003E-04 9,314E-03 ! protein import into nucleus GO:0006606 174 82 2,000 4,057E-04 9,35E-03 ! nuclear import GO:0051170 177 83 2,000 4,204E-04 9,598E-03 ! T cell activation GO:0042110 189 84 2,000 4,354E-04 9,849E-03 ! negative regulation of ion transport GO:0043271 25 18 1,000 4,499E-04 0,01008259 ! cell-substrate junction assembly GO:0007044 56 18 1,000 4,499E-04 9,991E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 4,499E-04 9,901E-03 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 4,499E-04 9,813E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,499E-04 9,726E-03 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 5,022E-04 0,01076242 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 5,022E-04 0,01066884 ! visual learning GO:0008542 38 19 1,000 5,022E-04 0,01057687 ! protein localization in nucleus GO:0034504 192 89 2,000 5,158E-04 0,01076912 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,574E-04 0,01153991 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,574E-04 0,01144294 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,574E-04 0,01134758 GO:0010675|regulation of cellular carbohydrate metabolic process, ! actin filament bundle formation GO:0051017 47 20 1,000 5,574E-04 0,0112538 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 5,574E-04 0,01116155 ! regulation of cell killing GO:0031341 46 21 1,000 6,154E-04 0,01222241 ! lipid phosphorylation GO:0046834 43 21 1,000 6,154E-04 0,01212385 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 6,154E-04 0,01202686 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 6,762E-04 0,01310981 ! vacuolar transport GO:0007034 41 22 1,000 6,762E-04 0,01300658 ! cell aging GO:0007569 48 22 1,000 6,762E-04 0,01290497 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,762E-04 0,01280493 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,762E-04 0,01270643 ! positive regulation of DNA replication GO:0045740 44 23 1,000 7,397E-04 0,01379483 ! visual behavior GO:0007632 46 23 1,000 7,397E-04 0,01369032 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 8,061E-04 0,01480596 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 8,061E-04 0,01469547 ! sex determination GO:0007530 48 24 1,000 8,061E-04 0,01458662 ! negative regulation of DNA replication GO:0008156 45 25 1,000 8,752E-04 0,01572077 ! receptor metabolic process GO:0043112 53 25 1,000 8,752E-04 0,01560602 ! protein tetramerization GO:0051262 57 25 1,000 8,752E-04 0,01549293 ! initiation of viral infection GO:0019059 60 26 1,000 9,47E-04 0,01664456 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 9,47E-04 0,01652567 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 1,099E-03 0,01904151 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,099E-03 0,01890741 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 1,179E-03 0,02014332 ! sensory perception of taste GO:0050909 41 30 1,000 1,262E-03 0,02140821 ! cell junction assembly GO:0034329 85 31 1,000 1,347E-03 0,02270132 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 1,436E-03 0,02402192 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 1,716E-03 0,02852442 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 1,716E-03 0,02833169 ! regulation of muscle development GO:0048634 82 36 1,000 1,815E-03 0,02976353 ! cell junction organization GO:0034330 96 37 1,000 1,917E-03 0,03121951 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 1,917E-03 0,03101276 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 2,128E-03 0,0342014 ! carbohydrate homeostasis GO:0033500 59 39 1,000 2,128E-03 0,03397786 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 2,128E-03 0,03375722 ! learning GO:0007612 82 40 1,000 2,237E-03 0,03526511 ! T cell differentiation GO:0030217 93 42 1,000 2,464E-03 0,03859112 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 2,464E-03 0,03834532 ! regulation of T cell differentiation GO:0045580 78 42 1,000 2,464E-03 0,03810262 ! glucose transport GO:0015758 66 43 1,000 2,582E-03 0,03966548 ! striated muscle cell differentiation GO:0051146 91 43 1,000 2,582E-03 0,03941757 ! hexose transport GO:0008645 68 44 1,000 2,701E-03 0,04099216 GO:0015749|monosaccharide transport, ! receptor-mediated endocytosis GO:0006898 98 45 1,000 2,824E-03 0,04258622 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 2,824E-03 0,04232496 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 2,949E-03 0,04392977 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 2,949E-03 0,04366353 ! cell growth GO:0016049 90 46 1,000 2,949E-03 0,0434005 ! regulation of adaptive immune response GO:0002819 92 48 1,000 3,207E-03 0,04691182 ! response to calcium ion GO:0051592 94 49 1,000 3,34E-03 0,04856253 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 3,34E-03 0,04827518 ! activation of caspase activity GO:0006919 95 50 1,000 3,475E-03 0,0499349 ! viral infectious cycle GO:0019058 104 51 1,000 3,613E-03 0,05161131 ! excretion GO:0007588 87 52 1,000 3,753E-03 0,05330399 ! positive regulation of growth GO:0045927 96 53 1,000 3,896E-03 0,05501254 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 3,896E-03 0,05469638 ! response to UV GO:0009411 120 55 1,000 4,189E-03 0,05847564 ! regulation of protein catabolic process GO:0042176 126 56 1,000 4,339E-03 0,06022943 ! positive regulation of caspase activity GO:0043280 108 57 1,000 4,492E-03 0,06199754 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 1,000 4,492E-03 0,06164924 ! regulation of intracellular transport GO:0032386 108 57 1,000 4,492E-03 0,06130483 ! positive regulation of cell migration GO:0030335 137 58 1,000 4,647E-03 0,06307095 ! aging GO:0007568 112 58 1,000 4,647E-03 0,0627225 ! positive regulation of organelle organization GO:0010638 108 58 1,000 4,647E-03 0,06237787 ! lipid modification GO:0030258 112 60 1,000 4,965E-03 0,06627959 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 5,127E-03 0,06807777 ! regulation of mitosis GO:0007088 112 63 1,000 5,46E-03 0,07209938 GO:0051783|regulation of nuclear division, ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 5,63E-03 0,07394234 ! positive regulation of cell motion GO:0051272 157 65 1,000 5,802E-03 0,07579699 ! activation of MAPK activity GO:0000187 124 67 1,000 6,154E-03 0,07996327 ! chromosome segregation GO:0007059 127 67 1,000 6,154E-03 0,07954018 ! positive regulation of T cell activation GO:0050870 124 68 1,000 6,333E-03 0,08142815 ! homeostasis of number of cells GO:0048872 131 69 1,000 6,515E-03 0,08332666 ! cell cycle checkpoint GO:0000075 145 71 1,000 6,885E-03 0,08760813 ! carbohydrate transport GO:0008643 114 72 1,000 7,074E-03 0,08954428 ! actin filament organization GO:0007015 167 72 1,000 7,074E-03 0,08908271 ! regulation of immune effector process GO:0002697 156 73 1,000 7,265E-03 0,0910207 ! regulation of caspase activity GO:0043281 136 74 1,000 7,459E-03 0,09296792 ! cell-matrix adhesion GO:0007160 181 76 1,000 7,853E-03 0,09738089 ! learning or memory GO:0007611 161 76 1,000 7,853E-03 0,09688907 ! lymphocyte differentiation GO:0030098 193 76 1,000 7,853E-03 0,09640219 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 8,053E-03 0,09836822 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 8,053E-03 0,09787882 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 8,256E-03 0,09984581 ! protein oligomerization GO:0051259 149 79 1,000 8,461E-03 0,10182092 ! regulation of synaptic transmission GO:0050804 159 79 1,000 8,461E-03 0,1013218 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 8,692E-03 0,10357961 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 8,692E-03 0,10307679 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 8,692E-03 0,10257884 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,692E-03 0,10208567 ! positive regulation of helicase activity GO:0051096 12 5 0,000 8,692E-03 0,10159722 ! neuron fate determination GO:0048664 7 5 0,000 8,692E-03 0,10111343 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,692E-03 0,10063422 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 8,692E-03 0,10015953 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 8,692E-03 0,09968929 ! polyol transport GO:0015791 12 5 0,000 8,692E-03 0,09922346 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,692E-03 0,09876195 ! response to superoxide GO:0000303 10 5 0,000 8,692E-03 0,09830472 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,692E-03 0,0978517 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 8,692E-03 0,09740284 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 8,692E-03 0,09695808 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,692E-03 0,09651736 ! female meiosis GO:0007143 10 5 0,000 8,692E-03 0,09608063 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 8,692E-03 0,09564784 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,692E-03 0,09521892 ! hypothalamus development GO:0021854 9 5 0,000 8,692E-03 0,09479384 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 8,692E-03 0,09437253 ! cobalt ion transport GO:0006824 11 5 0,000 8,692E-03 0,09395495 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 8,692E-03 0,09354105 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 8,692E-03 0,09313079 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,692E-03 0,0927241 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,692E-03 0,09232095 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 8,692E-03 0,0919213 ! embryonic camera-type eye development GO:0031076 12 5 0,000 8,692E-03 0,09152508 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,692E-03 0,09113227 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,692E-03 0,09074282 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 8,692E-03 0,09035668 ! transposition GO:0032196 9 5 0,000 8,692E-03 0,08997381 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 8,692E-03 0,08959417 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 8,692E-03 0,08921773 ! negative chemotaxis GO:0050919 16 5 0,000 8,692E-03 0,08884443 ! positive regulation of histone modification GO:0031058 6 5 0,000 8,692E-03 0,08847425 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,692E-03 0,08810713 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 8,692E-03 0,08774306 ! behavioral response to pain GO:0048266 10 5 0,000 8,692E-03 0,08738197 ! clathrin coat assembly GO:0048268 15 5 0,000 8,692E-03 0,08702385 ! Notch receptor processing GO:0007220 11 5 0,000 8,692E-03 0,08666865 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,692E-03 0,08631634 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 8,692E-03 0,08596688 ! micturition GO:0060073 9 5 0,000 8,692E-03 0,08562024 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,692E-03 0,08527638 ! copulation GO:0007620 9 5 0,000 8,692E-03 0,08493528 ! glial cell fate commitment GO:0021781 14 5 0,000 8,692E-03 0,08459689 ! protein maturation by protein folding GO:0022417 14 5 0,000 8,692E-03 0,08426119 ! bioluminescence GO:0008218 9 5 0,000 8,692E-03 0,08392814 ! spermidine metabolic process GO:0008216 7 5 0,000 8,692E-03 0,08359771 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,692E-03 0,08326988 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,692E-03 0,08294461 ! apoptotic cell clearance GO:0043277 23 5 0,000 8,692E-03 0,08262187 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,692E-03 0,08230163 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 8,692E-03 0,08198386 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,692E-03 0,08166854 ! grooming behavior GO:0007625 6 5 0,000 8,692E-03 0,08135563 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 8,692E-03 0,08104511 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,692E-03 0,08073696 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 8,692E-03 0,08043113 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,692E-03 0,08012762 ! response to protozoan GO:0001562 13 5 0,000 8,692E-03 0,07982639 ! lymph vessel development GO:0001945 10 5 0,000 8,692E-03 0,07952741 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 8,692E-03 0,07923067 ! endochondral ossification GO:0001958 17 5 0,000 8,692E-03 0,07893613 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,692E-03 0,07864378 ! single strand break repair GO:0000012 8 5 0,000 8,692E-03 0,07835358 ! parathyroid gland development GO:0060017 14 5 0,000 8,692E-03 0,07806551 ! anagen GO:0042640 7 5 0,000 8,692E-03 0,07777956 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,692E-03 0,07749569 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,692E-03 0,07721389 ! cytokine secretion GO:0050663 15 5 0,000 8,692E-03 0,07693413 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 8,692E-03 0,07665639 ! ceramide catabolic process GO:0046514 7 5 0,000 8,692E-03 0,07638065 ! skeletal myofibril assembly GO:0014866 12 5 0,000 8,692E-03 0,07610688 ! smooth muscle tissue development GO:0048745 32 5 0,000 8,692E-03 0,07583507 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,692E-03 0,07556519 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,692E-03 0,07529723 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,692E-03 0,07503116 ! cardiac muscle fiber development GO:0048739 12 5 0,000 8,692E-03 0,07476697 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,692E-03 0,07450463 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 8,692E-03 0,07424412 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,692E-03 0,07398543 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 8,692E-03 0,07372854 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,692E-03 0,07347342 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 8,692E-03 0,07322007 ! glycine biosynthetic process GO:0006545 7 5 0,000 8,692E-03 0,07296845 ! microvillus organization GO:0032528 8 5 0,000 8,692E-03 0,07271856 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 8,692E-03 0,07247037 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 8,692E-03 0,07222388 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 8,692E-03 0,07197905 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 8,692E-03 0,07173588 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 8,692E-03 0,07149434 ! polyol catabolic process GO:0046174 9 5 0,000 8,692E-03 0,07125443 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 8,692E-03 0,07101612 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 8,692E-03 0,0707794 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 8,692E-03 0,07054425 ! muscle cell migration GO:0014812 8 5 0,000 8,692E-03 0,07031066 ! mitochondrial fission GO:0000266 8 5 0,000 8,692E-03 0,07007861 ! sister chromatid cohesion GO:0007062 15 5 0,000 8,692E-03 0,06984809 ! response to tumor necrosis factor GO:0034612 10 5 0,000 8,692E-03 0,06961908 ! mRNA transcription GO:0009299 10 5 0,000 8,692E-03 0,06939157 ! nerve growth factor processing GO:0032455 9 5 0,000 8,692E-03 0,06916554 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 8,692E-03 0,06894097 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 8,692E-03 0,06871786 ! anaerobic glycolysis GO:0019642 6 5 0,000 8,692E-03 0,06849619 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,692E-03 0,06827595 ! monocyte activation GO:0042117 10 5 0,000 8,692E-03 0,06805711 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,692E-03 0,06783968 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,692E-03 0,06762363 ! response to food GO:0032094 6 5 0,000 8,692E-03 0,06740895 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,692E-03 0,06719563 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,692E-03 0,06698366 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 8,692E-03 0,06677302 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,692E-03 0,0665637 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 8,692E-03 0,06635569 ! forebrain neuron development GO:0021884 13 5 0,000 8,692E-03 0,06614897 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,692E-03 0,06594354 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 8,692E-03 0,06573938 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 8,692E-03 0,06553648 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,692E-03 0,06533483 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,692E-03 0,06513442 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 8,692E-03 0,06493523 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,692E-03 0,06473725 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 8,692E-03 0,06454048 ! lipid glycosylation GO:0030259 7 5 0,000 8,692E-03 0,06434491 ! nucleobase transport GO:0015851 6 5 0,000 8,692E-03 0,06415051 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,692E-03 0,06395729 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 8,692E-03 0,06376522 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 8,692E-03 0,06357431 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 8,692E-03 0,06338454 ! basic amino acid transport GO:0015802 12 5 0,000 8,692E-03 0,06319589 ! cellular glucose homeostasis GO:0001678 6 5 0,000 8,692E-03 0,06300837 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 8,692E-03 0,06282195 ! actin nucleation GO:0045010 11 5 0,000 8,692E-03 0,06263664 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,692E-03 0,06245241 ! depurination GO:0045007 5 5 0,000 8,692E-03 0,06226927 ! depyrimidination GO:0045008 10 5 0,000 8,692E-03 0,06208719 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,692E-03 0,06190618 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,692E-03 0,06172622 ! G2/M transition checkpoint GO:0031576 8 5 0,000 8,692E-03 0,0615473 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,692E-03 0,06136942 ! zinc ion homeostasis GO:0055069 9 5 0,000 8,692E-03 0,06119256 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 8,692E-03 0,06101672 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 8,692E-03 0,06084189 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,692E-03 0,06066806 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,692E-03 0,06049521 ! activated T cell proliferation GO:0050798 16 5 0,000 8,692E-03 0,06032335 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,692E-03 0,06015246 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 8,692E-03 0,05998254 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,692E-03 0,05981358 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,692E-03 0,05964556 ! gamma-delta T cell activation GO:0046629 6 5 0,000 8,692E-03 0,05947849 ! response to arsenic GO:0046685 11 5 0,000 8,692E-03 0,05931234 ! mast cell degranulation GO:0043303 7 5 0,000 8,692E-03 0,05914713 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 8,692E-03 0,05898283 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 8,692E-03 0,05881944 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 8,692E-03 0,05865696 ! response to mercury ion GO:0046689 8 5 0,000 8,692E-03 0,05849537 ! response to cadmium ion GO:0046686 7 5 0,000 8,692E-03 0,05833467 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 8,692E-03 0,05817485 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 8,692E-03 0,0580159 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 8,692E-03 0,05785782 ! bile acid biosynthetic process GO:0006699 7 5 0,000 8,692E-03 0,0577006 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 8,692E-03 0,05754423 ! ganglioside catabolic process GO:0006689 12 5 0,000 8,692E-03 0,0573887 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,692E-03 0,05723401 ! decidualization GO:0046697 11 5 0,000 8,692E-03 0,05708016 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 8,692E-03 0,05692713 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 8,692E-03 0,05677492 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 8,692E-03 0,05662352 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 8,692E-03 0,05647292 ! embryonic cleavage GO:0040016 6 5 0,000 8,692E-03 0,05632313 ! peroxisome fission GO:0016559 5 5 0,000 8,692E-03 0,05617413 ! histone demethylation GO:0016577 13 5 0,000 8,692E-03 0,05602591 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 8,692E-03 0,05587847 ! mitotic recombination GO:0006312 9 5 0,000 8,692E-03 0,05573181 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 8,692E-03 0,05558591 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,692E-03 0,05544078 ! regulation of sterol transport GO:0032371 7 5 0,000 8,692E-03 0,0552964 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,692E-03 0,05515278 ! enteric nervous system development GO:0048484 8 5 0,000 8,692E-03 0,05500989 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 8,692E-03 0,05486775 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 8,692E-03 0,05472634 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 8,692E-03 0,05458565 ! muscle cell proliferation GO:0033002 12 5 0,000 8,692E-03 0,05444569 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,692E-03 0,05430644 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 8,692E-03 0,05416791 ! B cell homeostasis GO:0001782 13 5 0,000 8,692E-03 0,05403007 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 8,692E-03 0,05389294 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,692E-03 0,0537565 ! metaphase GO:0051323 11 5 0,000 8,692E-03 0,05362076 ! melatonin biosynthetic process GO:0030187 7 5 0,000 8,692E-03 0,05348569 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 8,692E-03 0,05335131 ! cellular response to nutrient GO:0031670 8 5 0,000 8,692E-03 0,05321759 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,692E-03 0,05308455 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 8,692E-03 0,05295217 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 8,692E-03 0,05282045 ! regulation of hair follicle development GO:0051797 10 5 0,000 8,692E-03 0,05268938 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 8,692E-03 0,05255896 ! response to redox state GO:0051775 6 5 0,000 8,692E-03 0,05242918 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 8,692E-03 0,05230005 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 8,692E-03 0,05217155 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,692E-03 0,05204368 ! brown fat cell differentiation GO:0050873 7 5 0,000 8,692E-03 0,05191643 ! regulation of telomerase activity GO:0051972 7 5 0,000 8,692E-03 0,0517898 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,692E-03 0,05166379 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 8,692E-03 0,0515384 ! porphyrin catabolic process GO:0006787 12 5 0,000 8,692E-03 0,05141361 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 8,692E-03 0,05128942 ! striatum development GO:0021756 14 5 0,000 8,692E-03 0,05116583 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 8,692E-03 0,05104284 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,692E-03 0,05092043 ! glial cell migration GO:0008347 10 5 0,000 8,692E-03 0,05079861 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,692E-03 0,05067737 ! neural plate morphogenesis GO:0001839 7 5 0,000 8,692E-03 0,05055671 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 8,692E-03 0,05043663 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,692E-03 0,05031711 ! T cell activation during immune response GO:0002286 9 5 0,000 8,692E-03 0,05019815 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,692E-03 0,05007976 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,692E-03 0,04996193 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 8,692E-03 0,04984465 ! neuroprotection GO:0043526 8 5 0,000 8,692E-03 0,04972791 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,692E-03 0,04961173 ! regulation of sensory perception GO:0051931 8 5 0,000 8,692E-03 0,04949608 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,692E-03 0,04938098 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,692E-03 0,0492664 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 8,692E-03 0,04915236 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 8,692E-03 0,04903884 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,692E-03 0,04892585 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 8,692E-03 0,04881338 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,692E-03 0,04870142 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 8,692E-03 0,04858998 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 8,692E-03 0,04847904 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 8,692E-03 0,04836861 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,692E-03 0,04825868 ! spindle assembly GO:0051225 6 5 0,000 8,692E-03 0,04814925 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,692E-03 0,04804032 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,692E-03 0,04793187 ! protein palmitoylation GO:0018345 12 5 0,000 8,692E-03 0,04782392 ! drug metabolic process GO:0017144 7 5 0,000 8,692E-03 0,04771645 ! stem cell division GO:0017145 11 5 0,000 8,692E-03 0,04760946 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 8,692E-03 0,04750295 ! organ regeneration GO:0031100 7 5 0,000 8,692E-03 0,04739692 ! carnitine metabolic process GO:0009437 8 5 0,000 8,692E-03 0,04729136 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,692E-03 0,04718627 ! muscle cell differentiation GO:0042692 178 81 1,000 8,878E-03 0,04808847 ! response to hypoxia GO:0001666 178 81 1,000 8,878E-03 0,04798208 ! regulation of peptidase activity GO:0052547 150 82 1,000 9,089E-03 0,04901836 ! cell-substrate adhesion GO:0031589 189 82 1,000 9,089E-03 0,04891039 ! response to drug GO:0042493 149 83 1,000 9,303E-03 0,04995218 ! response to oxygen levels GO:0070482 183 83 1,000 9,303E-03 0,04984263 ! response to metal ion GO:0010038 158 84 1,000 9,52E-03 0,05088981 ! negative regulation of transport GO:0051051 164 85 1,000 9,738E-03 0,05194434 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 9,738E-03 0,05183117 ! positive regulation of cell activation GO:0050867 161 86 1,000 9,959E-03 0,05289089 GO:0002696|positive regulation of leukocyte activation, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0104211 0,05522504 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0104211 0,0551055 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0104211 0,05498648 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0104211 0,05486798 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0104211 0,05474998 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0104211 0,05463249 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0104211 0,05451551 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0104211 0,05439902 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0104211 0,05428303 ! response to oxygen radical GO:0000305 11 6 0,000 0,0104211 0,05416753 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0104211 0,05405253 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,0104211 0,05393801 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0104211 0,05382398 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0104211 0,05371042 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0104211 0,05359735 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0104211 0,05348475 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0104211 0,05337262 ! forebrain regionalization GO:0021871 9 6 0,000 0,0104211 0,05326097 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0104211 0,05314977 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0104211 0,05303904 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0104211 0,05292878 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0104211 0,05281897 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,0104211 0,05270961 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0104211 0,05260071 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0104211 0,05249225 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0104211 0,05238424 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0104211 0,05227668 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0104211 0,05216955 ! malate metabolic process GO:0006108 13 6 0,000 0,0104211 0,05206287 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0104211 0,05195662 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0104211 0,0518508 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0104211 0,05174541 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0104211 0,05164045 ! protein refolding GO:0042026 15 6 0,000 0,0104211 0,05153591 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0104211 0,0514318 ! opsonization GO:0008228 8 6 0,000 0,0104211 0,05132811 ! mating behavior GO:0007617 7 6 0,000 0,0104211 0,05122483 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0104211 0,05112197 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,0104211 0,05101952 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0104211 0,05091748 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0104211 0,05081585 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0104211 0,05071462 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0104211 0,0506138 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0104211 0,05051338 ! toxin metabolic process GO:0009404 11 6 0,000 0,0104211 0,05041335 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0104211 0,05031372 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,0104211 0,05021448 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0104211 0,05011563 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0104211 0,05001717 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0104211 0,0499191 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0104211 0,04982141 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0104211 0,0497241 ! thymic T cell selection GO:0045061 16 6 0,000 0,0104211 0,04962718 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0104211 0,04953063 ! protein lipoylation GO:0009249 10 6 0,000 0,0104211 0,04943445 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0104211 0,04933865 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0104211 0,04924321 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0104211 0,04914815 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0104211 0,04905345 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0104211 0,04895912 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0104211 0,04886515 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0104211 0,04877154 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,0104211 0,04867828 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0104211 0,04858538 ! hyperosmotic response GO:0006972 10 6 0,000 0,0104211 0,04849284 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,0104211 0,04840065 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0104211 0,04830881 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0104211 0,04821731 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0104211 0,04812617 ! urea metabolic process GO:0019627 7 6 0,000 0,0104211 0,04803536 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0104211 0,0479449 ! neutrophil activation GO:0042119 7 6 0,000 0,0104211 0,04785478 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0104211 0,04776499 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0104211 0,04767555 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0104211 0,04758643 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0104211 0,04749765 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,0104211 0,0474092 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0104211 0,04732108 ! neuron apoptosis GO:0051402 15 6 0,000 0,0104211 0,04723329 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0104211 0,04714582 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0104211 0,04705867 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0104211 0,04697185 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0104211 0,04688534 ! carnitine transport GO:0015879 10 6 0,000 0,0104211 0,04679916 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0104211 0,04671329 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0104211 0,04662773 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0104211 0,04654249 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0104211 0,04645756 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0104211 0,04637294 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0104211 0,04628862 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0104211 0,04620461 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,0104211 0,04612091 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0104211 0,04603751 ! establishment of spindle localization GO:0051293 16 6 0,000 0,0104211 0,04595441 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0104211 0,04587161 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0104211 0,0457891 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,0104211 0,0457069 ! response to UV-C GO:0010225 14 6 0,000 0,0104211 0,04562498 ! astrocyte development GO:0014002 16 6 0,000 0,0104211 0,04554337 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0104211 0,04546204 ! interaction with symbiont GO:0051702 14 6 0,000 0,0104211 0,045381 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0104211 0,04530025 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0104211 0,04521979 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0104211 0,04513961 ! response to copper ion GO:0046688 10 6 0,000 0,0104211 0,04505972 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0104211 0,04498011 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,0104211 0,04490078 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0104211 0,04482173 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0104211 0,04474296 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0104211 0,04466446 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0104211 0,04458624 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0104211 0,04450829 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0104211 0,04443061 ! hair follicle maturation GO:0048820 8 6 0,000 0,0104211 0,04435321 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0104211 0,04427607 ! Schwann cell development GO:0014044 15 6 0,000 0,0104211 0,0441992 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0104211 0,0441226 ! response to pheromone GO:0019236 6 6 0,000 0,0104211 0,04404627 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0104211 0,04397019 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0104211 0,04389438 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,0104211 0,04381883 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0104211 0,04374354 ! subpallium development GO:0021544 15 6 0,000 0,0104211 0,04366851 ! neural tube patterning GO:0021532 8 6 0,000 0,0104211 0,04359374 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,0104211 0,04351922 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0104211 0,04344495 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0104211 0,04337094 ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,0104211 0,04329718 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,0104211 0,04322367 ! oxygen homeostasis GO:0032364 10 6 0,000 0,0104211 0,04315041 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0104211 0,0430774 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0104211 0,04300463 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0104211 0,04293211 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0104211 0,04285983 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0104211 0,0427878 ! plasminogen activation GO:0031639 9 6 0,000 0,0104211 0,04271601 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,0104211 0,04264446 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0104211 0,04257315 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,0104211 0,04250207 ! protein deubiquitination GO:0016579 16 6 0,000 0,0104211 0,04243124 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,0104211 0,04236063 ! protein destabilization GO:0031648 9 6 0,000 0,0104211 0,04229027 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0104211 0,04222014 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0104211 0,04215023 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0104211 0,04208056 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0104211 0,04201112 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0104211 0,04194191 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0104211 0,04187293 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0104211 0,04180417 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0104211 0,04173564 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0104211 0,04166733 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0104211 0,04159925 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0104211 0,04153139 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0104211 0,04146375 ! neural plate development GO:0001840 9 6 0,000 0,0104211 0,04139633 ! catecholamine transport GO:0051937 9 6 0,000 0,0104211 0,04132913 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0104211 0,04126214 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0104211 0,04119537 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,0104211 0,04112882 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0104211 0,04106249 ! maternal placenta development GO:0001893 12 6 0,000 0,0104211 0,04099636 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0104211 0,04093045 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,0104211 0,04086475 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0104211 0,04079927 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0104211 0,04073399 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0104211 0,04066892 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,0104211 0,04060405 GO:0055081|anion homeostasis, ! regulation of neurological system process GO:0031644 175 89 1,000 0,01063454 0,04136971 ! response to inorganic substance GO:0010035 173 90 1,000 0,01086412 0,04219562 ! response to unfolded protein GO:0006986 139 90 1,000 0,01086412 0,04212865 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,01086412 0,04206188 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,01132984 0,04379557 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01156596 0,04463766 ! tRNA transcription GO:0009304 17 7 0,000 0,01214753 0,04680822 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01214753 0,04673451 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01214753 0,04666102 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01214753 0,04658777 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01214753 0,04651475 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01214753 0,04644196 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01214753 0,04636939 ! sleep GO:0030431 16 7 0,000 0,01214753 0,04629705 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01214753 0,04622494 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01214753 0,04615305 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01214753 0,04608138 ! prostate gland development GO:0030850 14 7 0,000 0,01214753 0,04600994 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01214753 0,04593872 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01214753 0,04586771 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01214753 0,04579693 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01214753 0,04572637 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01214753 0,04565602 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01214753 0,04558589 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01214753 0,04551597 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01214753 0,04544627 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01214753 0,04537678 ! glycolipid transport GO:0046836 11 7 0,000 0,01214753 0,0453075 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01214753 0,04523843 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01214753 0,04516958 ! neuron adhesion GO:0007158 14 7 0,000 0,01214753 0,04510093 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01214753 0,04503249 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01214753 0,04496426 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01214753 0,04489624 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01214753 0,04482842 ! mRNA stabilization GO:0048255 18 7 0,000 0,01214753 0,0447608 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01214753 0,04469339 ! fibril organization GO:0043206 17 7 0,000 0,01214753 0,04462618 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01214753 0,04455918 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01214753 0,04449237 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01214753 0,04442577 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01214753 0,04435936 ! lipoprotein transport GO:0042953 14 7 0,000 0,01214753 0,04429315 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01214753 0,04422714 ! rhythmic behavior GO:0007622 17 7 0,000 0,01214753 0,04416133 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01214753 0,04409571 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01214753 0,04403028 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01214753 0,04396505 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01214753 0,04390002 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01214753 0,04383517 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01214753 0,04377052 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01214753 0,04370606 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01214753 0,04364178 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01214753 0,0435777 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01214753 0,0435138 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01214753 0,04345009 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01214753 0,04338657 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01214753 0,04332323 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01214753 0,04326008 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01214753 0,04319711 ! spinal cord patterning GO:0021511 14 7 0,000 0,01214753 0,04313432 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01214753 0,04307171 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01214753 0,04300929 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01214753 0,04294705 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01214753 0,04288499 ! adrenal gland development GO:0030325 17 7 0,000 0,01214753 0,0428231 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01214753 0,0427614 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01214753 0,04269987 ! ovulation GO:0030728 10 7 0,000 0,01214753 0,04263852 ! adenohypophysis development GO:0021984 11 7 0,000 0,01214753 0,04257735 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01214753 0,04251635 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01214753 0,04245552 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01214753 0,04239487 ! microtubule nucleation GO:0007020 21 7 0,000 0,01214753 0,0423344 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01214753 0,04227409 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01214753 0,04221396 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01214753 0,04215399 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01214753 0,0420942 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01214753 0,04203458 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01214753 0,04197512 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01214753 0,04191584 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01214753 0,04185672 ! galactose metabolic process GO:0006012 13 7 0,000 0,01214753 0,04179776 ! vesicle fusion GO:0006906 20 7 0,000 0,01214753 0,04173898 ! response to dietary excess GO:0002021 8 7 0,000 0,01214753 0,04168035 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01214753 0,0416219 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01214753 0,0415636 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01214753 0,04150547 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01214753 0,0414475 ! organ growth GO:0035265 15 7 0,000 0,01214753 0,0413897 ! nucleoside transport GO:0015858 11 7 0,000 0,01214753 0,04133205 ! nucleoside salvage GO:0043174 11 7 0,000 0,01214753 0,04127456 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01214753 0,04121724 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01214753 0,04116007 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01214753 0,04110306 ! parturition GO:0007567 16 7 0,000 0,01214753 0,04104621 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01214753 0,04098952 ! rRNA modification GO:0000154 14 7 0,000 0,01214753 0,04093298 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01214753 0,0408766 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01214753 0,04082037 ! monocyte differentiation GO:0030224 16 7 0,000 0,01214753 0,0407643 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01214753 0,04070838 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01214753 0,04065262 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01214753 0,04059701 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01214753 0,04054155 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01214753 0,04048624 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01214753 0,04043108 ! fibrinolysis GO:0042730 11 7 0,000 0,01214753 0,04037607 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01214753 0,04032121 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01214753 0,0402665 ! eating behavior GO:0042755 8 7 0,000 0,01214753 0,04021194 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01214753 0,04015753 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01214753 0,04010326 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01214753 0,04004914 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01214753 0,03999516 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01214753 0,03994133 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01214753 0,03988765 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01214753 0,03983411 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01214753 0,03978071 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01214753 0,03972746 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01214753 0,03967435 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01214753 0,03962138 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01214753 0,03956855 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01214753 0,03951586 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01214753 0,03946331 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01214753 0,03941091 ! histone ubiquitination GO:0016574 9 7 0,000 0,01214753 0,03935864 ! regulation of meiosis GO:0040020 12 7 0,000 0,01214753 0,03930651 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01214753 0,03925451 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01214753 0,03920266 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01214753 0,03915094 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01214753 0,03909936 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01214753 0,03904791 ! transcription termination GO:0006353 14 7 0,000 0,01214753 0,0389966 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01214753 0,03894542 ! anaphase GO:0051322 18 7 0,000 0,01214753 0,03889438 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01214753 0,03884347 ! axonal fasciculation GO:0007413 19 7 0,000 0,01214753 0,03879269 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01214753 0,03874205 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01214753 0,03869154 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01214753 0,03864116 ! diuresis GO:0030146 12 7 0,000 0,01214753 0,03859091 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01214753 0,03854079 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01214753 0,03849081 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01214753 0,03844095 ! antibiotic transport GO:0042891 9 7 0,000 0,01214753 0,03839122 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01214753 0,03834162 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01214753 0,03829214 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01214753 0,0382428 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01214753 0,03819358 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01214753 0,03814449 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01214753 0,03809552 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01214753 0,03804668 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01214753 0,03799797 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01214753 0,03794938 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01214753 0,03790091 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01214753 0,03785257 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01214753 0,03780435 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01214753 0,03775625 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01214753 0,03770827 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01214753 0,03766042 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01214753 0,03761269 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01214753 0,03756508 ! muscle adaptation GO:0043500 13 7 0,000 0,01214753 0,03751759 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01214753 0,03747022 ! retina homeostasis GO:0001895 12 7 0,000 0,01214753 0,03742297 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01214753 0,03737583 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01214753 0,03732882 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01214753 0,03728192 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01214753 0,03723515 ! response to protein stimulus GO:0051789 158 96 1,000 0,01228726 0,03761626 ! regulation of T cell activation GO:0050863 175 96 1,000 0,01228726 0,03756918 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,01277883 0,03902336 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,013871 0,04230567 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,013871 0,04225292 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,013871 0,0422003 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,013871 0,04214781 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,013871 0,04209546 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,013871 0,04204323 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,013871 0,04199113 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,013871 0,04193916 ! male meiosis GO:0007140 9 8 0,000 0,013871 0,04188732 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,013871 0,04183561 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,013871 0,04178402 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,013871 0,04173256 ! meiotic prophase I GO:0007128 14 8 0,000 0,013871 0,04168123 ! response to zinc ion GO:0010043 12 8 0,000 0,013871 0,04163003 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,013871 0,04157895 ! oligopeptide transport GO:0006857 16 8 0,000 0,013871 0,04152799 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,013871 0,04147716 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,013871 0,04142646 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,013871 0,04137588 ! signal peptide processing GO:0006465 12 8 0,000 0,013871 0,04132542 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,013871 0,04127508 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,013871 0,04122487 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,013871 0,04117478 ! succinate metabolic process GO:0006105 17 8 0,000 0,013871 0,04112481 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,013871 0,04107496 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,013871 0,04102523 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,013871 0,04097562 ! estrogen metabolic process GO:0008210 17 8 0,000 0,013871 0,04092614 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,013871 0,04087677 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,013871 0,04082752 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,013871 0,04077839 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,013871 0,04072938 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,013871 0,04068048 ! reflex GO:0060004 17 8 0,000 0,013871 0,0406317 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,013871 0,04058304 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,013871 0,0405345 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,013871 0,04048607 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,013871 0,04043776 ! pigment granule organization GO:0048753 17 8 0,000 0,013871 0,04038956 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,013871 0,04034148 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,013871 0,04029351 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,013871 0,04024566 ! astrocyte differentiation GO:0048708 19 8 0,000 0,013871 0,04019791 ! histidine catabolic process GO:0006548 10 8 0,000 0,013871 0,04015029 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,013871 0,04010277 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,013871 0,04005537 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,013871 0,04000808 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,013871 0,0399609 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,013871 0,03991383 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,013871 0,03986687 ! melanin metabolic process GO:0006582 17 8 0,000 0,013871 0,03982003 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,013871 0,03977329 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,013871 0,03972666 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,013871 0,03968014 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,013871 0,03963373 ! macrophage activation GO:0042116 13 8 0,000 0,013871 0,03958743 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,013871 0,03954124 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,013871 0,03949515 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,013871 0,03944918 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,013871 0,0394033 ! purine salvage GO:0043101 12 8 0,000 0,013871 0,03935754 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,013871 0,03931188 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,013871 0,03926633 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,013871 0,03922088 ! osteoblast development GO:0002076 17 8 0,000 0,013871 0,03917554 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,013871 0,0391303 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,013871 0,03908517 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,013871 0,03904014 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,013871 0,03899521 ! response to UV-B GO:0010224 17 8 0,000 0,013871 0,03895039 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,013871 0,03890567 ! intermediate filament organization GO:0045109 12 8 0,000 0,013871 0,03886106 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,013871 0,03881654 ! cellular extravasation GO:0045123 13 8 0,000 0,013871 0,03877213 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,013871 0,03872782 ! response to antibiotic GO:0046677 11 8 0,000 0,013871 0,03868361 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,013871 0,0386395 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,013871 0,03859549 ! DNA topological change GO:0006265 12 8 0,000 0,013871 0,03855158 ! response to tropane GO:0014073 15 8 0,000 0,013871 0,03850777 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,013871 0,03846407 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,013871 0,03842046 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,013871 0,03837694 ! mast cell activation GO:0045576 14 8 0,000 0,013871 0,03833353 ! multicellular organismal aging GO:0010259 20 8 0,000 0,013871 0,03829022 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,013871 0,038247 ! gas homeostasis GO:0033483 14 8 0,000 0,013871 0,03820388 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,013871 0,03816086 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,013871 0,03811793 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,013871 0,0380751 ! nucleosome disassembly GO:0006337 14 8 0,000 0,013871 0,03803237 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,013871 0,03798973 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,013871 0,03794719 ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,013871 0,03790474 ! intracellular lipid transport GO:0032365 16 8 0,000 0,013871 0,03786239 ! response to tumor cell GO:0002347 16 8 0,000 0,013871 0,03782014 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,013871 0,03777797 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,013871 0,0377359 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,013871 0,03769393 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,013871 0,03765205 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,013871 0,03761026 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,013871 0,03756856 ! hormone catabolic process GO:0042447 17 8 0,000 0,013871 0,03752696 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,013871 0,03748544 GO:0046479|glycosphingolipid catabolic process, ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,013871 0,03744402 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,013871 0,0374027 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,013871 0,03736146 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,013871 0,03732031 ! adult feeding behavior GO:0008343 10 8 0,000 0,013871 0,03727925 ! ATP catabolic process GO:0006200 11 8 0,000 0,013871 0,03723829 ! blastocyst growth GO:0001832 19 8 0,000 0,013871 0,03719741 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,013871 0,03715662 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,013871 0,03711593 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,013871 0,03707532 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,013871 0,0370348 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,013871 0,03699437 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,013871 0,03695403 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,013871 0,03691377 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,013871 0,0368736 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,013871 0,03683352 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,013871 0,03679353 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,013871 0,03675362 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,013871 0,0367138 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,013871 0,03667407 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,013871 0,03663442 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,013871 0,03659486 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,013871 0,03655538 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,013871 0,03651599 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,013871 0,03647669 ! axon extension GO:0048675 16 9 0,000 0,0155915 0,04095704 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0155915 0,04091304 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0155915 0,04086915 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0155915 0,04082534 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0155915 0,04078163 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0155915 0,04073802 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0155915 0,04069449 ! reproductive behavior GO:0019098 22 9 0,000 0,0155915 0,04065106 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0155915 0,04060772 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0155915 0,04056448 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0155915 0,04052132 ! UTP metabolic process GO:0046051 10 9 0,000 0,0155915 0,04047826 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0155915 0,04043529 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,0155915 0,04039241 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0155915 0,04034962 ! artery development GO:0060840 25 9 0,000 0,0155915 0,04030693 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0155915 0,04026432 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0155915 0,0402218 ! equilibrioception GO:0050957 20 9 0,000 0,0155915 0,04017937 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0155915 0,04013703 ! chemosensory behavior GO:0007635 21 9 0,000 0,0155915 0,04009478 ! microtubule bundle formation GO:0001578 22 9 0,000 0,0155915 0,04005262 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0155915 0,04001055 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0155915 0,03996857 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0155915 0,03992667 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0155915 0,03988486 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0155915 0,03984314 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0155915 0,03980151 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0155915 0,03975996 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0155915 0,0397185 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0155915 0,03967713 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0155915 0,03963584 ! protein targeting to ER GO:0045047 25 9 0,000 0,0155915 0,03959464 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0155915 0,03955353 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0155915 0,03951249 ! T cell selection GO:0045058 27 9 0,000 0,0155915 0,03947155 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0155915 0,03943069 ! glycine catabolic process GO:0006546 15 9 0,000 0,0155915 0,03938991 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0155915 0,03934922 ! endosome organization GO:0007032 20 9 0,000 0,0155915 0,03930861 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0155915 0,03926809 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0155915 0,03922765 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0155915 0,03918729 ! mannose metabolic process GO:0006013 13 9 0,000 0,0155915 0,03914701 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0155915 0,03910682 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0155915 0,03906671 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0155915 0,03902669 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0155915 0,03898674 ! receptor clustering GO:0043113 20 9 0,000 0,0155915 0,03894688 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0155915 0,03890709 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0155915 0,03886739 ! retinol metabolic process GO:0042572 20 9 0,000 0,0155915 0,03882777 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0155915 0,03878823 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0155915 0,03874877 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0155915 0,03870939 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0155915 0,0386701 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0155915 0,03863088 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0155915 0,03859174 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0155915 0,03855268 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0155915 0,0385137 ! response to amine stimulus GO:0014075 13 9 0,000 0,0155915 0,03847479 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0155915 0,03843597 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0155915 0,03839722 ! erythrocyte development GO:0048821 17 9 0,000 0,0155915 0,03835855 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0155915 0,03831996 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0155915 0,03828145 ! renal water homeostasis GO:0003091 15 9 0,000 0,0155915 0,03824302 ! postreplication repair GO:0006301 25 9 0,000 0,0155915 0,03820466 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0155915 0,03816638 ! icosanoid secretion GO:0032309 15 9 0,000 0,0155915 0,03812817 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0155915 0,03809004 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0155915 0,03805199 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0155915 0,03801402 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0155915 0,03797612 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0155915 0,03793829 ! sterol catabolic process GO:0016127 14 9 0,000 0,0155915 0,03790054 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0155915 0,03786287 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0155915 0,03782527 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0155915 0,03778774 ! S phase GO:0051320 10 9 0,000 0,0155915 0,03775029 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0155915 0,03771292 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0155915 0,03767561 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0155915 0,03763838 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0155915 0,03760123 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0155915 0,03756415 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0155915 0,03752714 ! purine base metabolic process GO:0006144 25 9 0,000 0,0155915 0,0374902 ! pigment granule transport GO:0051904 17 9 0,000 0,0155915 0,03745334 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0155915 0,03741655 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0155915 0,03737983 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0155915 0,03734318 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0155915 0,03730661 ! mitochondrion localization GO:0051646 18 9 0,000 0,0155915 0,0372701 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01730906 0,04133532 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,01730906 0,04129495 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01730906 0,04125467 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01730906 0,04121446 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01730906 0,04117433 ! associative learning GO:0008306 21 10 0,000 0,01730906 0,04113427 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01730906 0,0410943 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01730906 0,0410544 ! phosphate transport GO:0006817 24 10 0,000 0,01730906 0,04101458 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01730906 0,04097484 ! CTP metabolic process GO:0046036 11 10 0,000 0,01730906 0,04093517 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01730906 0,04089558 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01730906 0,04085607 ! GTP metabolic process GO:0046039 11 10 0,000 0,01730906 0,04081663 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01730906 0,04077727 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01730906 0,04073799 ! social behavior GO:0035176 29 10 0,000 0,01730906 0,04069878 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01730906 0,04065965 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01730906 0,04062059 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01730906 0,0405816 ! androgen metabolic process GO:0008209 17 10 0,000 0,01730906 0,0405427 ! phospholipid efflux GO:0033700 19 10 0,000 0,01730906 0,04050386 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01730906 0,0404651 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01730906 0,04042642 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01730906 0,04038781 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01730906 0,04034927 ! lung alveolus development GO:0048286 26 10 0,000 0,01730906 0,0403108 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01730906 0,04027241 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01730906 0,04023409 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01730906 0,04019585 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01730906 0,04015768 ! endoderm development GO:0007492 18 10 0,000 0,01730906 0,04011958 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01730906 0,04008155 ! arginine catabolic process GO:0006527 17 10 0,000 0,01730906 0,04004359 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01730906 0,04000571 ! proline metabolic process GO:0006560 13 10 0,000 0,01730906 0,03996789 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01730906 0,03993015 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01730906 0,03989248 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01730906 0,03985488 ! V(D)J recombination GO:0033151 34 10 0,000 0,01730906 0,03981736 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01730906 0,0397799 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01730906 0,03974251 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01730906 0,03970519 ! B cell proliferation GO:0042100 19 10 0,000 0,01730906 0,03966795 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01730906 0,03963077 ! multicellular organism growth GO:0035264 19 10 0,000 0,01730906 0,03959366 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01730906 0,03955663 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01730906 0,03951966 ! ruffle organization GO:0031529 17 10 0,000 0,01730906 0,03948276 ! epithelial cell development GO:0002064 21 10 0,000 0,01730906 0,03944593 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01730906 0,03940916 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01730906 0,03937247 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01730906 0,03933584 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01730906 0,03929929 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01730906 0,0392628 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01730906 0,03922637 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01730906 0,03919002 ! motor axon guidance GO:0008045 22 10 0,000 0,01730906 0,03915373 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01730906 0,03911751 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01730906 0,03908136 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01730906 0,03904527 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01730906 0,03900925 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01730906 0,0389733 ! segment specification GO:0007379 15 10 0,000 0,01730906 0,03893741 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01730906 0,03890159 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01730906 0,03886584 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01730906 0,03883015 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01730906 0,03879452 ! response to dsRNA GO:0043331 23 10 0,000 0,01730906 0,03875897 ! DNA ligation GO:0006266 18 10 0,000 0,01730906 0,03872347 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01730906 0,03868804 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01730906 0,03865268 ! melanosome localization GO:0032400 16 10 0,000 0,01730906 0,03861738 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01730906 0,03858215 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01730906 0,03854698 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01730906 0,03851187 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01730906 0,03847683 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01730906 0,03844185 ! induction of an organ GO:0001759 17 10 0,000 0,01730906 0,03840693 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01730906 0,03837208 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01730906 0,03833729 ! protein sumoylation GO:0016925 17 10 0,000 0,01730906 0,03830257 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01730906 0,0382679 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01730906 0,0382333 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01730906 0,03819876 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01730906 0,03816429 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01730906 0,03812988 ! salivary gland development GO:0007431 28 10 0,000 0,01730906 0,03809552 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01730906 0,03806124 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01730906 0,03802701 ! midbrain development GO:0030901 14 10 0,000 0,01730906 0,03799284 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01730906 0,03795874 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01730906 0,03792469 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01730906 0,03789071 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01730906 0,03785679 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01730906 0,03782293 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01730906 0,03778913 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01730906 0,03775539 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01730906 0,03772171 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01730906 0,03768809 ! detection of calcium ion GO:0005513 24 10 0,000 0,01730906 0,03765453 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01730906 0,03762103 ! blastocyst formation GO:0001825 18 10 0,000 0,01730906 0,03758758 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01730906 0,0375542 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01730906 0,03752088 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01730906 0,03748762 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01730906 0,03745441 ! response to nicotine GO:0035094 20 10 0,000 0,01730906 0,03742127 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01730906 0,03738818 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01902367 0,04105549 ! respiratory burst GO:0045730 17 11 0,000 0,01902367 0,04101926 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01902367 0,04098308 ! neuron fate specification GO:0048665 18 11 0,000 0,01902367 0,04094697 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01902367 0,04091093 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01902367 0,04087495 ! thyroid gland development GO:0030878 26 11 0,000 0,01902367 0,04083903 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01902367 0,04080318 ! synapsis GO:0007129 14 11 0,000 0,01902367 0,04076738 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01902367 0,04073165 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01902367 0,04069599 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,01902367 0,04066038 ! response to pain GO:0048265 27 11 0,000 0,01902367 0,04062484 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01902367 0,04058936 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01902367 0,04055394 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01902367 0,04051858 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01902367 0,04048329 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01902367 0,04044806 ! bone resorption GO:0045453 16 11 0,000 0,01902367 0,04041288 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01902367 0,04037777 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,01902367 0,04034272 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01902367 0,04030773 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01902367 0,0402728 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01902367 0,04023794 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01902367 0,04020313 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01902367 0,04016838 ! L-serine metabolic process GO:0006563 21 11 0,000 0,01902367 0,04013369 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01902367 0,04009907 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01902367 0,0400645 ! UV protection GO:0009650 20 11 0,000 0,01902367 0,04002999 ! adult heart development GO:0007512 16 11 0,000 0,01902367 0,03999554 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01902367 0,03996115 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01902367 0,03992682 ! macroautophagy GO:0016236 19 11 0,000 0,01902367 0,03989255 ! temperature homeostasis GO:0001659 18 11 0,000 0,01902367 0,03985833 ! behavioral fear response GO:0001662 27 11 0,000 0,01902367 0,03982418 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01902367 0,03979008 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01902367 0,03975605 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01902367 0,03972207 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01902367 0,03968814 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01902367 0,03965428 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01902367 0,03962047 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01902367 0,03958673 ! regulation of organ growth GO:0046620 14 11 0,000 0,01902367 0,03955304 ! pigment granule localization GO:0051875 20 11 0,000 0,01902367 0,0395194 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01902367 0,03948583 ! vasoconstriction GO:0042310 20 11 0,000 0,01902367 0,03945231 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01902367 0,03941884 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01902367 0,03938544 ! embryonic axis specification GO:0000578 19 11 0,000 0,01902367 0,03935209 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01902367 0,0393188 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01902367 0,03928556 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01902367 0,03925238 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01902367 0,03921925 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01902367 0,03918619 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01902367 0,03915317 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01902367 0,03912022 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01902367 0,03908731 ! prophase GO:0051324 17 11 0,000 0,01902367 0,03905447 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01902367 0,03902168 ! nucleosome positioning GO:0016584 15 11 0,000 0,01902367 0,03898894 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01902367 0,03895626 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01902367 0,03892363 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01902367 0,03889106 ! apical protein localization GO:0045176 18 11 0,000 0,01902367 0,03885854 ! acid secretion GO:0046717 20 11 0,000 0,01902367 0,03882608 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01902367 0,03879367 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01902367 0,03876131 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01902367 0,03872901 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01902367 0,03869677 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01902367 0,03866457 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01902367 0,03863243 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01902367 0,03860035 ! cholesterol efflux GO:0033344 21 11 0,000 0,01902367 0,03856831 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01902367 0,03853633 ! oocyte development GO:0048599 20 11 0,000 0,01902367 0,0385044 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01902367 0,03847253 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01902367 0,03844071 ! embryonic gut development GO:0048566 19 11 0,000 0,01902367 0,03840894 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01902367 0,03837722 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01902367 0,03834556 ! activation of innate immune response GO:0002218 16 11 0,000 0,01902367 0,03831395 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01902367 0,03828239 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01902367 0,03825088 ! lysogeny GO:0030069 22 11 0,000 0,01902367 0,03821942 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01902367 0,03818802 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01902367 0,03815666 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01902367 0,03812536 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02073533 0,04152165 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02073533 0,04148764 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02073533 0,04145369 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02073533 0,0414198 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02073533 0,04138596 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02073533 0,04135217 ! protein complex disassembly GO:0043241 28 12 0,000 0,02073533 0,04131844 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02073533 0,04128477 ! hippocampus development GO:0021766 29 12 0,000 0,02073533 0,04125115 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02073533 0,04121758 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02073533 0,04118407 ! T cell proliferation GO:0042098 32 12 0,000 0,02073533 0,04115062 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02073533 0,04111722 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02073533 0,04108387 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02073533 0,04105058 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02073533 0,04101734 ! drug transport GO:0015893 16 12 0,000 0,02073533 0,04098415 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02073533 0,04095102 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02073533 0,04091794 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02073533 0,04088492 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02073533 0,04085194 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02073533 0,04081903 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02073533 0,04078616 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02073533 0,04075335 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02073533 0,04072059 ! lipid digestion GO:0044241 21 12 0,000 0,02073533 0,04068788 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02073533 0,04065522 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02073533 0,04062262 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02073533 0,04059007 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02073533 0,04055757 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02073533 0,04052513 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02073533 0,04049273 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02073533 0,04046039 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02073533 0,0404281 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02073533 0,04039586 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02073533 0,04036367 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02073533 0,04033154 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02073533 0,04029945 ! cranial nerve development GO:0021545 23 12 0,000 0,02073533 0,04026742 ! fucose catabolic process GO:0019317 25 12 0,000 0,02073533 0,04023543 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02073533 0,0402035 ! histone acetylation GO:0016573 27 12 0,000 0,02073533 0,04017162 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02073533 0,04013979 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02073533 0,040108 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02073533 0,04007627 ! zymogen activation GO:0031638 18 12 0,000 0,02073533 0,04004459 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02073533 0,04001296 ! T cell homeostasis GO:0043029 28 12 0,000 0,02073533 0,03998138 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02073533 0,03994985 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02073533 0,03991837 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02073533 0,03988694 ! oocyte differentiation GO:0009994 21 12 0,000 0,02073533 0,03985555 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02073533 0,03982422 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02073533 0,03979294 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02073533 0,0397617 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02073533 0,03973052 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02073533 0,03969938 ! defense response to fungus GO:0050832 15 12 0,000 0,02073533 0,03966829 ! developmental induction GO:0031128 22 12 0,000 0,02073533 0,03963725 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02073533 0,03960626 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02073533 0,03957532 ! response to cold GO:0009409 17 12 0,000 0,02073533 0,03954443 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02073533 0,03951358 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02073533 0,03948278 ! localization within membrane GO:0051668 26 12 0,000 0,02073533 0,03945203 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02244405 0,0426699 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02244405 0,04263672 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02244405 0,04260359 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02244405 0,04257052 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02244405 0,04253749 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02244405 0,04250452 ! peroxisomal transport GO:0043574 28 13 0,000 0,02244405 0,04247159 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02244405 0,04243872 ! cartilage condensation GO:0001502 22 13 0,000 0,02244405 0,0424059 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02244405 0,04237313 ! organelle fusion GO:0048284 36 13 0,000 0,02244405 0,04234041 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02244405 0,04230774 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02244405 0,04227512 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02244405 0,04224255 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02244405 0,04221003 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02244405 0,04217756 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02244405 0,04214514 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02244405 0,04211277 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02244405 0,04208045 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02244405 0,04204818 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02244405 0,04201596 ! methionine metabolic process GO:0006555 31 13 0,000 0,02244405 0,04198379 ! plasma membrane organization GO:0007009 27 13 0,000 0,02244405 0,04195166 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02244405 0,04191959 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02244405 0,04188757 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02244405 0,04185559 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02244405 0,04182366 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02244405 0,04179179 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02244405 0,04175996 ! exocrine system development GO:0035272 34 13 0,000 0,02244405 0,04172818 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02244405 0,04169644 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02244405 0,04166476 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02244405 0,04163312 ! L-glutamate transport GO:0015813 30 13 0,000 0,02244405 0,04160154 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02244405 0,04157 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02244405 0,0415385 ! protein homotetramerization GO:0051289 24 13 0,000 0,02244405 0,04150706 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02244405 0,04147566 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02244405 0,04144431 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02244405 0,04141301 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02244405 0,04138175 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02244405 0,04135055 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02244405 0,04131939 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,02244405 0,04128827 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02244405 0,0412572 ! histone methylation GO:0016571 29 13 0,000 0,02244405 0,04122618 ! chromatin silencing GO:0006342 29 13 0,000 0,02244405 0,04119521 ! gland morphogenesis GO:0022612 31 13 0,000 0,02244405 0,04116428 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02244405 0,0411334 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02244405 0,04110257 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02244405 0,04107178 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02244405 0,04104104 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02244405 0,04101034 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02244405 0,04097969 ! spleen development GO:0048536 24 13 0,000 0,02244405 0,04094908 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02244405 0,04091853 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02244405 0,04088801 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02244405 0,04085754 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02244405 0,04082712 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02244405 0,04079674 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02244405 0,04076641 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02244405 0,04073613 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02244405 0,04070588 ! insulin secretion GO:0030073 24 13 0,000 0,02244405 0,04067569 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02244405 0,04064553 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02244405 0,04061543 ! acrosome reaction GO:0007340 19 13 0,000 0,02244405 0,04058536 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02244405 0,04055534 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02244405 0,04052537 ! rRNA transcription GO:0009303 28 14 0,000 0,02414985 0,04357317 ! regulation of S phase GO:0033261 26 14 0,000 0,02414985 0,04354101 ! water transport GO:0006833 21 14 0,000 0,02414985 0,0435089 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02414985 0,04347684 ! non-recombinational repair GO:0000726 29 14 0,000 0,02414985 0,04344483 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02414985 0,04341286 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02414985 0,04338094 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02414985 0,04334906 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02414985 0,04331723 ! lipid localization GO:0010876 32 14 0,000 0,02414985 0,04328545 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02414985 0,04325372 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02414985 0,04322203 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02414985 0,04319039 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02414985 0,0431588 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02414985 0,04312725 ! arginine metabolic process GO:0006525 21 14 0,000 0,02414985 0,04309574 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02414985 0,04306429 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02414985 0,04303288 ! regulation of heart rate GO:0002027 25 14 0,000 0,02414985 0,04300151 ! fear response GO:0042596 34 14 0,000 0,02414985 0,04297019 ! organic alcohol transport GO:0015850 29 14 0,000 0,02414985 0,04293892 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02414985 0,04290769 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02414985 0,04287651 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02414985 0,04284537 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02414985 0,04281428 ! bone mineralization GO:0030282 18 14 0,000 0,02414985 0,04278323 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02414985 0,04275223 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02414985 0,04272127 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02414985 0,04269036 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02414985 0,04265949 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02414985 0,04262867 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02414985 0,04259789 ! ribosome assembly GO:0042255 18 14 0,000 0,02414985 0,04256715 ! cerebellum development GO:0021549 23 14 0,000 0,02414985 0,04253646 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02414985 0,04250582 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02414985 0,04247521 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02414985 0,04244466 ! response to gamma radiation GO:0010332 30 14 0,000 0,02414985 0,04241414 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02414985 0,04238367 ! NADP metabolic process GO:0006739 24 14 0,000 0,02414985 0,04235325 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02414985 0,04232286 ! oxygen transport GO:0015671 22 14 0,000 0,02414985 0,04229253 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02414985 0,04226223 ! male genitalia development GO:0030539 26 14 0,000 0,02414985 0,04223198 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02414985 0,04220177 ! regulation of axon extension GO:0030516 43 14 0,000 0,02414985 0,0421716 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02414985 0,04214148 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02414985 0,0421114 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02414985 0,04208136 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02585271 0,04501651 ! lactation GO:0007595 30 15 0,000 0,02585271 0,04498445 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,02585271 0,04495243 ! reproductive cellular process GO:0048610 22 15 0,000 0,02585271 0,04492046 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02585271 0,04488853 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02585271 0,04485665 ! superoxide anion generation GO:0042554 22 15 0,000 0,02585271 0,04482482 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02585271 0,04479303 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02585271 0,04476128 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02585271 0,04472958 ! copper ion transport GO:0006825 22 15 0,000 0,02585271 0,04469792 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02585271 0,04466631 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02585271 0,04463475 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02585271 0,04460322 ! sulfate transport GO:0008272 27 15 0,000 0,02585271 0,04457175 ! response to cAMP GO:0051591 25 15 0,000 0,02585271 0,04454031 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02585271 0,04450893 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02585271 0,04447758 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02585271 0,04444628 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02585271 0,04441503 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02585271 0,04438381 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02585271 0,04435264 ! vesicle coating GO:0006901 38 15 0,000 0,02585271 0,04432152 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02585271 0,04429044 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02585271 0,0442594 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02585271 0,04422841 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02585271 0,04419746 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02585271 0,04416655 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02585271 0,04413569 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02585271 0,04410486 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02585271 0,04407409 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02585271 0,04404335 ! regulation of vasodilation GO:0042312 27 15 0,000 0,02585271 0,04401266 ! histone deacetylation GO:0016575 24 15 0,000 0,02585271 0,04398201 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02585271 0,0439514 ! water homeostasis GO:0030104 28 15 0,000 0,02585271 0,04392084 ! cofactor transport GO:0051181 30 15 0,000 0,02585271 0,04389032 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02585271 0,04385984 ! muscle maintenance GO:0046716 26 15 0,000 0,02585271 0,0438294 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02585271 0,04379901 ! intestinal absorption GO:0050892 31 15 0,000 0,02585271 0,04376865 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02585271 0,04373834 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02585271 0,04370807 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02585271 0,04367785 ! cell killing GO:0001906 32 15 0,000 0,02585271 0,04364766 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02585271 0,04361752 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02585271 0,04358742 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02585271 0,04355736 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02585271 0,04352734 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02585271 0,04349736 ! actin filament polymerization GO:0030041 27 15 0,000 0,02585271 0,04346742 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02585271 0,04343753 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02755265 0,04626194 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02755265 0,04623016 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02755265 0,04619843 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02755265 0,04616675 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02755265 0,0461351 ! bone remodeling GO:0046849 28 16 0,000 0,02755265 0,0461035 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02755265 0,04607195 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02755265 0,04604044 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02755265 0,04600897 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02755265 0,04597754 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02755265 0,04594616 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02755265 0,04591481 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02755265 0,04588352 ! startle response GO:0001964 28 16 0,000 0,02755265 0,04585226 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02755265 0,04582105 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02755265 0,04578988 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02755265 0,04575875 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02755265 0,04572766 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02755265 0,04569662 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02755265 0,04566562 ! pituitary gland development GO:0021983 30 16 0,000 0,02755265 0,04563466 ! response to osmotic stress GO:0006970 27 16 0,000 0,02755265 0,04560374 ! fructose metabolic process GO:0006000 25 16 0,000 0,02755265 0,04557286 ! L-amino acid transport GO:0015807 33 16 0,000 0,02755265 0,04554203 ! stem cell development GO:0048864 46 16 0,000 0,02755265 0,04551124 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02755265 0,04548048 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02755265 0,04544978 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02755265 0,04541911 ! axon cargo transport GO:0008088 46 16 0,000 0,02755265 0,04538848 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02755265 0,0453579 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02755265 0,04532735 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,02755265 0,04529685 ! DNA replication initiation GO:0006270 28 16 0,000 0,02755265 0,04526639 ! neuron recognition GO:0008038 40 16 0,000 0,02755265 0,04523597 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02755265 0,04520559 ! tissue regeneration GO:0042246 27 16 0,000 0,02755265 0,04517525 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02755265 0,04514495 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02755265 0,04511469 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02755265 0,04508447 ! biomineral formation GO:0031214 22 16 0,000 0,02755265 0,0450543 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02755265 0,04502416 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02755265 0,04499406 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02755265 0,04496401 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02755265 0,04493399 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02755265 0,04490401 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02755265 0,04487408 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02755265 0,04484418 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02755265 0,04481433 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02755265 0,04478451 ! peptide hormone processing GO:0016486 27 16 0,000 0,02755265 0,04475473 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02924967 0,04747969 ! metencephalon development GO:0022037 32 17 0,000 0,02924967 0,04744817 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02924967 0,04741668 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02924967 0,04738524 ! signal complex assembly GO:0007172 47 17 0,000 0,02924967 0,04735384 ! endothelial cell migration GO:0043542 31 17 0,000 0,02924967 0,04732248 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02924967 0,04729116 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02924967 0,04725988 ! glial cell development GO:0021782 28 17 0,000 0,02924967 0,04722864 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02924967 0,04719745 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02924967 0,0471663 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02924967 0,04713518 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02924967 0,04710411 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02924967 0,04707308 ! myoblast differentiation GO:0045445 50 17 0,000 0,02924967 0,04704209 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02924967 0,04701114 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02924967 0,04698024 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02924967 0,04694937 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02924967 0,04691854 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02924967 0,04688775 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02924967 0,04685701 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02924967 0,0468263 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02924967 0,04679564 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02924967 0,04676501 ! membrane budding GO:0006900 42 17 0,000 0,02924967 0,04673443 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02924967 0,04670388 ! regulation of protein binding GO:0043393 33 17 0,000 0,02924967 0,04667338 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02924967 0,04664291 ! genitalia development GO:0048806 32 17 0,000 0,02924967 0,04661248 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02924967 0,0465821 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02924967 0,04655175 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02924967 0,04652144 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02924967 0,04649118 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02924967 0,04646095 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02924967 0,04643076 ! steroid catabolic process GO:0006706 34 17 0,000 0,02924967 0,04640061 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02924967 0,0463705 ! gas transport GO:0015669 26 17 0,000 0,02924967 0,04634043 ! organic cation transport GO:0015695 32 17 0,000 0,02924967 0,04631039 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02924967 0,0462804 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02924967 0,04625045 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,03094377 0,04889757 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03094377 0,04886596 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03094377 0,04883439 ! limbic system development GO:0021761 40 18 0,000 0,03094377 0,04880287 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03094377 0,04877138 GO:0050886|endocrine process, ! adult walking behavior GO:0007628 36 18 0,000 0,03094377 0,04873994 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03094377 0,04870853 ! heart looping GO:0001947 34 18 0,000 0,03094377 0,04867717 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03094377 0,04864584 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03094377 0,04861456 ! centrosome cycle GO:0007098 26 18 0,000 0,03094377 0,04858332 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03094377 0,04855211 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03094377 0,04852095 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03094377 0,04848983 ! glycine metabolic process GO:0006544 30 18 0,000 0,03094377 0,04845874 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03094377 0,0484277 ! response to retinoic acid GO:0032526 31 18 0,000 0,03094377 0,0483967 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03094377 0,04836573 ! DNA integration GO:0015074 32 18 0,000 0,03094377 0,04833481 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03094377 0,04830392 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03094377 0,04827308 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03094377 0,04824227 ! neural crest cell migration GO:0001755 41 18 0,000 0,03094377 0,0482115 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03094377 0,04818078 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03094377 0,04815009 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03094377 0,04811944 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03094377 0,04808883 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03094377 0,04805826 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03094377 0,04802773 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03094377 0,04799723 ! detection of bacterium GO:0016045 22 18 0,000 0,03094377 0,04796678 ! nerve development GO:0021675 34 18 0,000 0,03094377 0,04793636 ! defense response to virus GO:0051607 43 18 0,000 0,03094377 0,04790598 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03094377 0,04787564 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03094377 0,04784534 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03263497 0,05042836 ! positive regulation of translation GO:0045727 31 19 0,000 0,03263497 0,05039648 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03263497 0,05036465 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03263497 0,05033285 ! neuron maturation GO:0042551 46 19 0,000 0,03263497 0,05030109 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03263497 0,05026938 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03263497 0,0502377 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03263497 0,05020607 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03263497 0,05017447 ! inositol metabolic process GO:0006020 33 19 0,000 0,03263497 0,05014292 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03263497 0,0501114 ! memory GO:0007613 34 19 0,000 0,03263497 0,05007992 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03263497 0,05004848 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03263497 0,05001709 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03263497 0,04998573 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03263497 0,04995441 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03263497 0,04992313 ! cerebral cortex development GO:0021987 40 19 0,000 0,03263497 0,04989189 ! pigmentation during development GO:0048066 42 19 0,000 0,03263497 0,04986069 ! response to vitamin A GO:0033189 32 19 0,000 0,03263497 0,04982952 ! heme metabolic process GO:0042168 40 19 0,000 0,03263497 0,0497984 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03263497 0,04976731 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03263497 0,04973627 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03263497 0,04970526 ! response to fungus GO:0009620 26 19 0,000 0,03263497 0,04967429 ! peptide cross-linking GO:0018149 39 19 0,000 0,03263497 0,04964336 ! protein export from nucleus GO:0006611 40 19 0,000 0,03263497 0,04961247 ! heart process GO:0003015 32 19 0,000 0,03263497 0,04958161 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03263497 0,0495508 ! cellular pigmentation GO:0033059 37 19 0,000 0,03263497 0,04952002 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03263497 0,04948928 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03263497 0,04945858 ! vitamin transport GO:0051180 31 19 0,000 0,03263497 0,04942792 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03263497 0,0493973 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03263497 0,04936671 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03263497 0,04933616 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03263497 0,04930565 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03263497 0,04927518 ! cilium assembly GO:0042384 38 19 0,000 0,03263497 0,04924474 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03263497 0,04921434 ! protein secretion GO:0009306 45 20 0,000 0,03432327 0,0517284 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03432327 0,05169651 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03432327 0,05166466 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03432327 0,05163284 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03432327 0,05160107 ! skin development GO:0043588 42 20 0,000 0,03432327 0,05156933 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03432327 0,05153764 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03432327 0,05150598 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,03432327 0,05147436 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03432327 0,05144278 ! response to vitamin GO:0033273 36 20 0,000 0,03432327 0,05141124 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03432327 0,05137974 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03432327 0,05134828 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03432327 0,05131685 ! response to alkaloid GO:0043279 38 20 0,000 0,03432327 0,05128547 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03432327 0,05125412 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,03432327 0,05122281 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03432327 0,05119154 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03432327 0,0511603 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03432327 0,05112911 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03432327 0,05109795 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03432327 0,05106683 ! body fluid secretion GO:0007589 33 20 0,000 0,03432327 0,05103575 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03432327 0,05100471 ! peptide secretion GO:0002790 38 20 0,000 0,03432327 0,0509737 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03432327 0,05094273 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,03432327 0,0509118 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03432327 0,05088091 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03432327 0,05085005 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03432327 0,05081923 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03432327 0,05078845 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,03432327 0,05075771 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03432327 0,050727 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03432327 0,05069633 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03432327 0,0506657 ! regulation of glucose import GO:0046324 30 20 0,000 0,03432327 0,05063511 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03432327 0,05060455 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03432327 0,05057403 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03432327 0,05054354 ! negative regulation of translation GO:0017148 32 20 0,000 0,03432327 0,05051309 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03432327 0,05048268 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,03600866 0,0529297 ! hormone secretion GO:0046879 39 21 0,000 0,03600866 0,05289787 ! cAMP metabolic process GO:0046058 41 21 0,000 0,03600866 0,05286608 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,03600866 0,05283433 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,03600866 0,05280261 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,03600866 0,05277094 ! ovarian follicle development GO:0001541 39 21 0,000 0,03600866 0,0527393 ! smooth muscle contraction GO:0006939 48 21 0,000 0,03600866 0,0527077 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,03600866 0,05267614 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,03600866 0,05264462 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,03600866 0,05261313 ! plasma membrane fusion GO:0045026 33 21 0,000 0,03600866 0,05258168 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,03600866 0,05255027 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,03600866 0,0525189 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,03600866 0,05248756 ! sensory perception of pain GO:0019233 33 21 0,000 0,03600866 0,05245626 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,03600866 0,052425 ! diencephalon development GO:0021536 36 21 0,000 0,03600866 0,05239378 ! collagen fibril organization GO:0030199 62 21 0,000 0,03600866 0,05236259 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,03600866 0,05233144 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,03600866 0,05230033 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,03600866 0,05226925 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,03600866 0,05223822 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,03600866 0,05220721 ! collagen catabolic process GO:0030574 29 21 0,000 0,03600866 0,05217625 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,03600866 0,05214532 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,03600866 0,05211443 ! sperm-egg recognition GO:0035036 23 21 0,000 0,03600866 0,05208357 ! actin filament-based movement GO:0030048 47 21 0,000 0,03600866 0,05205275 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,03600866 0,05202197 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03769116 0,05442051 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03769116 0,05438837 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03769116 0,05435626 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03769116 0,05432419 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03769116 0,05429216 ! microtubule-based transport GO:0010970 59 22 0,000 0,03769116 0,05426017 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,03769116 0,05422821 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03769116 0,05419629 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,03769116 0,05416441 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03769116 0,05413257 ! cellular response to starvation GO:0009267 37 22 0,000 0,03769116 0,05410077 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03769116 0,054069 ! fucose metabolic process GO:0006004 44 22 0,000 0,03769116 0,05403727 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03769116 0,05400557 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03769116 0,05397392 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03769116 0,0539423 ! ureteric bud development GO:0001657 50 22 0,000 0,03769116 0,05391072 ! stem cell differentiation GO:0048863 57 22 0,000 0,03769116 0,05387917 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03769116 0,05384766 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,03769116 0,05381619 ! cytolysis GO:0019835 27 22 0,000 0,03769116 0,05378476 ! renal system process GO:0003014 42 22 0,000 0,03769116 0,05375336 ! vasodilation GO:0042311 40 22 0,000 0,03769116 0,053722 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03769116 0,05369067 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03769116 0,05365938 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,03769116 0,05362813 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03769116 0,05359692 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03769116 0,05356574 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03769116 0,0535346 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,03769116 0,05350349 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03769116 0,05347242 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03769116 0,05344138 ! sarcomere organization GO:0045214 32 22 0,000 0,03769116 0,05341039 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,03769116 0,05337942 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03769116 0,0533485 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03769116 0,05331761 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03769116 0,05328675 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03769116 0,05325593 ! gut development GO:0048565 44 22 0,000 0,03769116 0,05322515 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03769116 0,0531944 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03769116 0,05316369 ! protein stabilization GO:0050821 41 22 0,000 0,03769116 0,05313301 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03937077 0,05546874 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03937077 0,05543677 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03937077 0,05540484 ! gluconeogenesis GO:0006094 38 23 0,000 0,03937077 0,05537294 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03937077 0,05534108 ! viral genome replication GO:0019079 44 23 0,000 0,03937077 0,05530926 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03937077 0,05527747 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03937077 0,05524572 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03937077 0,055214 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03937077 0,05518233 ! regeneration GO:0031099 42 23 0,000 0,03937077 0,05515068 ! axis specification GO:0009798 43 23 0,000 0,03937077 0,05511908 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,03937077 0,05508751 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,03937077 0,05505598 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03937077 0,05502448 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03937077 0,05499302 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03937077 0,0549616 ! peroxisome organization GO:0007031 43 23 0,000 0,03937077 0,05493021 ! lysosome organization GO:0007040 47 23 0,000 0,03937077 0,05489886 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03937077 0,05486754 ! vesicle targeting GO:0006903 49 23 0,000 0,03937077 0,05483626 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03937077 0,05480501 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03937077 0,0547738 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03937077 0,05474263 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03937077 0,05471149 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03937077 0,05468038 ! DNA modification GO:0006304 36 23 0,000 0,03937077 0,05464932 ! fatty acid transport GO:0015908 47 23 0,000 0,03937077 0,05461828 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03937077 0,05458728 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03937077 0,05455632 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03937077 0,05452539 ! hormone transport GO:0009914 41 23 0,000 0,03937077 0,0544945 ! cell-cell recognition GO:0009988 28 23 0,000 0,03937077 0,05446364 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03937077 0,05443282 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03937077 0,05440203 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03937077 0,05437128 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0410475 0,05665482 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0410475 0,05662283 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0410475 0,05659088 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0410475 0,05655896 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0410475 0,05652708 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0410475 0,05649523 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0410475 0,05646342 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0410475 0,05643165 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0410475 0,05639991 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,0410475 0,05636821 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0410475 0,05633654 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0410475 0,05630491 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0410475 0,05627331 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0410475 0,05624175 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0410475 0,05621022 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0410475 0,05617873 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0410475 0,05614728 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0410475 0,05611586 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,0410475 0,05608447 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0410475 0,05605312 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0410475 0,05602181 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0410475 0,05599053 ! membrane depolarization GO:0051899 45 24 0,000 0,0410475 0,05595928 ! pallium development GO:0021543 56 24 0,000 0,0410475 0,05592807 ! oogenesis GO:0048477 44 24 0,000 0,0410475 0,0558969 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0410475 0,05586576 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0410475 0,05583465 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0410475 0,05580358 ! platelet activation GO:0030168 41 24 0,000 0,0410475 0,05577255 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0410475 0,05574154 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0410475 0,05571058 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0410475 0,05567964 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0410475 0,05564874 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0410475 0,05561788 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0410475 0,05558705 ! regulation of amine transport GO:0051952 41 24 0,000 0,0410475 0,05555625 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,0410475 0,05552549 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,04272135 0,05775775 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,04272135 0,0577258 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,04272135 0,05769389 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,04272135 0,05766201 ! leukocyte adhesion GO:0007159 55 25 0,000 0,04272135 0,05763018 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,04272135 0,05759837 ! phototransduction GO:0007602 37 25 0,000 0,04272135 0,0575666 ! keratinization GO:0031424 37 25 0,000 0,04272135 0,05753487 ! vasculogenesis GO:0001570 49 25 0,000 0,04272135 0,05750317 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,04272135 0,0574715 ! vacuole organization GO:0007033 49 25 0,000 0,04272135 0,05743987 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,04272135 0,05740828 ! chromosome condensation GO:0030261 48 25 0,000 0,04272135 0,05737672 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,04272135 0,05734519 ! regulation of behavior GO:0050795 48 25 0,000 0,04272135 0,0573137 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,04272135 0,05728224 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,04272135 0,05725082 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,04272135 0,05721943 ! immunoglobulin production GO:0002377 62 25 0,000 0,04272135 0,05718808 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,04272135 0,05715676 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,04272135 0,05712548 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,04272135 0,05709423 ! liver development GO:0001889 55 25 0,000 0,04272135 0,05706301 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,04439232 0,05926253 ! myelination GO:0042552 50 26 0,000 0,04439232 0,05923017 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,04439232 0,05919783 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,04439232 0,05916554 ! molting cycle process GO:0022404 52 26 0,000 0,04439232 0,05913328 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,04439232 0,05910105 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,04439232 0,05906886 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,04439232 0,05903671 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,04439232 0,05900459 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,04439232 0,0589725 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,04439232 0,05894045 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,04439232 0,05890844 ! digestive system process GO:0022600 49 26 0,000 0,04439232 0,05887646 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,04439232 0,05884451 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,04439232 0,0588126 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,04439232 0,05878072 ! osteoblast differentiation GO:0001649 63 26 0,000 0,04439232 0,05874888 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,04439232 0,05871707 ! neural crest cell development GO:0014032 59 26 0,000 0,04439232 0,0586853 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,04439232 0,05865356 ! negative regulation of cell development GO:0010721 83 26 0,000 0,04439232 0,05862186 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,04439232 0,05859019 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,04439232 0,05855855 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,04439232 0,05852695 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,04439232 0,05849538 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,04439232 0,05846385 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,04439232 0,05843235 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,04439232 0,05840088 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,04439232 0,05836945 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,04439232 0,05833805 ! blastocyst development GO:0001824 50 26 0,000 0,04439232 0,05830668 ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,04439232 0,05827535 ! neural tube closure GO:0001843 58 26 0,000 0,04439232 0,05824406 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,04439232 0,05821279 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,04439232 0,05818156 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,04439232 0,05815037 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,04606042 0,06030311 ! embryonic pattern specification GO:0009880 49 27 0,000 0,04606042 0,06027081 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,04606042 0,06023855 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,04606042 0,06020632 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,04606042 0,06017412 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,04606042 0,06014196 ! iron ion transport GO:0006826 65 27 0,000 0,04606042 0,06010983 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,04606042 0,06007774 ! superoxide metabolic process GO:0006801 41 27 0,000 0,04606042 0,06004568 ! tube lumen formation GO:0035148 59 27 0,000 0,04606042 0,06001366 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,04606042 0,05998167 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,04606042 0,05994971 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,04606042 0,05991779 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,04606042 0,0598859 ! response to starvation GO:0042594 47 27 0,000 0,04606042 0,05985405 ! response to toxin GO:0009636 49 27 0,000 0,04606042 0,05982223 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,04606042 0,05979044 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,04606042 0,05975869 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,04606042 0,05972697 ! leukocyte proliferation GO:0070661 59 27 0,000 0,04606042 0,05969528 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,04606042 0,05966363 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,04772566 0,06178791 ! neuron fate commitment GO:0048663 52 28 0,000 0,04772566 0,06175518 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,04772566 0,06172249 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,04772566 0,06168983 ! protein amino acid acylation GO:0043543 59 28 0,000 0,04772566 0,06165721 ! vesicle docking GO:0048278 55 28 0,000 0,04772566 0,06162462 ! circadian rhythm GO:0007623 56 28 0,000 0,04772566 0,06159207 ! dendrite development GO:0016358 67 28 0,000 0,04772566 0,06155955 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,04772566 0,06152706 ! fat cell differentiation GO:0045444 57 28 0,000 0,04772566 0,06149461 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,04772566 0,0614622 ! sperm motility GO:0030317 37 28 0,000 0,04772566 0,06142981 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,04772566 0,06139746 ! base-excision repair GO:0006284 41 28 0,000 0,04772566 0,06136515 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,04772566 0,06133287 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,04772566 0,06130062 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,04772566 0,06126841 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,04772566 0,06123623 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,04772566 0,06120409 ! glutathione metabolic process GO:0006749 42 28 0,000 0,04772566 0,06117198 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,04772566 0,0611399 ! lipid oxidation GO:0034440 48 28 0,000 0,04772566 0,06110785 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,04772566 0,06107584 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,04772566 0,06104387 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,04938804 0,06313709 ! translational initiation GO:0006413 66 29 0,000 0,04938804 0,06310407 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,04938804 0,06307108 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,04938804 0,06303813 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,04938804 0,06300521 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,04938804 0,06297232 ! autophagy GO:0006914 47 29 0,000 0,04938804 0,06293947 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,04938804 0,06290666 ! primary neural tube formation GO:0014020 61 29 0,000 0,04938804 0,06287388 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,04938804 0,06284113 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,04938804 0,06280842 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,04938804 0,06277574 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,04938804 0,0627431 ! somitogenesis GO:0001756 52 29 0,000 0,04938804 0,06271049 ! synaptogenesis GO:0007416 46 29 0,000 0,04938804 0,06267791 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,04938804 0,06264537 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,04938804 0,06261286 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,04938804 0,06258038 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,05104756 0,06464966 ! phenol metabolic process GO:0018958 56 30 0,000 0,05104756 0,06461616 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,05104756 0,0645827 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,05104756 0,06454927 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,05104756 0,06451588 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,05104756 0,06448252 ! acute-phase response GO:0006953 50 30 0,000 0,05104756 0,06444919 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,05104756 0,0644159 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,05104756 0,06438265 ! myofibril assembly GO:0030239 50 30 0,000 0,05104756 0,06434943 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,05104756 0,06431624 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,05104756 0,06428309 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,05104756 0,06424997 ! cell fate determination GO:0001709 64 30 0,000 0,05104756 0,06421688 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,05104756 0,06418383 ! phospholipid transport GO:0015914 65 30 0,000 0,05104756 0,06415082 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,05104756 0,06411783 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,05104756 0,06408489 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,05104756 0,06405197 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,05104756 0,06401909 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,05104756 0,06398624 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,05104756 0,06395343 ! regulation of coagulation GO:0050818 52 30 0,000 0,05104756 0,06392065 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,05270423 0,06596129 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,05270423 0,06592751 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,05270423 0,06589378 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,05270423 0,06586007 ! regulation of innate immune response GO:0045088 57 31 0,000 0,05270423 0,0658264 ! ovulation cycle process GO:0022602 55 31 0,000 0,05270423 0,06579276 ! peptide transport GO:0015833 60 31 0,000 0,05270423 0,06575916 ! male gonad development GO:0008584 56 31 0,000 0,05270423 0,06572559 ! iron ion homeostasis GO:0055072 60 31 0,000 0,05270423 0,06569206 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,05270423 0,06565856 ! detection of light stimulus GO:0009583 44 31 0,000 0,05270423 0,0656251 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,05270423 0,06559166 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,05270423 0,06555827 ! natural killer cell activation GO:0030101 50 31 0,000 0,05270423 0,0655249 ! ensheathment of neurons GO:0007272 64 31 0,000 0,05270423 0,06549158 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,05270423 0,06545828 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,05270423 0,06542502 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,05270423 0,06539179 ! eye morphogenesis GO:0048592 65 31 0,000 0,05270423 0,0653586 ! response to heat GO:0009408 54 31 0,000 0,05270423 0,06532544 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,05270423 0,06529231 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,05435806 0,06730701 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,05435806 0,06727292 ! collagen metabolic process GO:0032963 49 32 0,000 0,05435806 0,06723885 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,05435806 0,06720483 ! spindle organization GO:0007051 50 32 0,000 0,05435806 0,06717083 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,05435806 0,06713687 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,05435806 0,06710295 ! metanephros development GO:0001656 81 32 0,000 0,05435806 0,06706906 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,05435806 0,0670352 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,05435806 0,06700138 ! muscle cell development GO:0055001 52 32 0,000 0,05435806 0,06696759 ! mesoderm formation GO:0001707 73 32 0,000 0,05435806 0,06693384 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,05435806 0,06690012 ! ovulation cycle GO:0042698 57 32 0,000 0,05435806 0,06686643 ! peripheral nervous system development GO:0007422 68 32 0,000 0,05435806 0,06683278 ! BMP signaling pathway GO:0030509 71 32 0,000 0,05435806 0,06679916 ! hindbrain development GO:0030902 65 32 0,000 0,05435806 0,06676558 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,05435806 0,06673203 ! gene silencing GO:0016458 71 32 0,000 0,05435806 0,06669851 ! regulation of pH GO:0006885 56 33 0,000 0,05600904 0,06868981 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,05600904 0,06865534 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,05600904 0,06862091 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,05600904 0,06858651 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,05600904 0,06855215 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,05600904 0,06851782 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,05600904 0,06848353 ! response to ionizing radiation GO:0010212 74 33 0,000 0,05600904 0,06844927 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,05600904 0,06841505 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,05600904 0,06838086 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,05600904 0,0683467 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,05600904 0,06831258 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,05600904 0,06827849 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,05600904 0,06824444 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,05600904 0,06821041 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,05765719 0,07018262 ! glial cell differentiation GO:0010001 67 34 0,000 0,05765719 0,07014767 ! post-embryonic development GO:0009791 76 34 0,000 0,05765719 0,07011275 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,05765719 0,07007787 ! cholesterol transport GO:0030301 62 34 0,000 0,05765719 0,07004302 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,05765719 0,07000821 ! spliceosome assembly GO:0000245 75 34 0,000 0,05765719 0,06997343 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,05765719 0,06993869 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,05765719 0,06990398 ! formation of primary germ layer GO:0001704 76 34 0,000 0,05765719 0,06986931 ! cell fate specification GO:0001708 56 34 0,000 0,05765719 0,06983467 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,05765719 0,06980006 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,05765719 0,06976549 ! adult locomotory behavior GO:0008344 62 34 0,000 0,05765719 0,06973095 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,05930251 0,07168532 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,05930251 0,07164987 ! negative regulation of secretion GO:0051048 68 35 0,000 0,05930251 0,07161445 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,05930251 0,07157907 ! membrane docking GO:0022406 69 35 0,000 0,05930251 0,07154372 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,05930251 0,07150841 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,05930251 0,07147313 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,05930251 0,07143789 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,05930251 0,07140268 ! ceramide metabolic process GO:0006672 72 35 0,000 0,05930251 0,0713675 ! telencephalon development GO:0021537 81 35 0,000 0,05930251 0,07133237 ! sterol transport GO:0015918 63 35 0,000 0,05930251 0,07129726 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,05930251 0,07126219 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,05930251 0,07122716 ! placenta development GO:0001890 53 35 0,000 0,05930251 0,07119215 ! vesicle localization GO:0051648 70 35 0,000 0,05930251 0,07115719 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,060945 0,07309212 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,060945 0,07305625 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,060945 0,07302042 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,060945 0,07298463 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,060945 0,07294887 ! positive regulation of cell development GO:0010720 85 36 0,000 0,060945 0,07291315 ! protein targeting to membrane GO:0006612 75 36 0,000 0,060945 0,07287746 ! regulation of proteolysis GO:0030162 77 36 0,000 0,060945 0,0728418 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,060945 0,07280618 ! aerobic respiration GO:0009060 56 36 0,000 0,060945 0,0727706 ! cytokine production GO:0001816 68 36 0,000 0,060945 0,07273505 ! embryonic organ development GO:0048568 67 36 0,000 0,060945 0,07269953 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,060945 0,07266405 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,060945 0,07262861 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,06258467 0,07454625 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,06258467 0,07450992 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,06258467 0,07447363 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,06258467 0,07443737 ! sister chromatid segregation GO:0000819 65 37 0,000 0,06258467 0,07440115 ! odontogenesis GO:0042476 74 37 0,000 0,06258467 0,07436496 ! actomyosin structure organization GO:0031032 68 37 0,000 0,06258467 0,07432881 ! tissue remodeling GO:0048771 78 37 0,000 0,06258467 0,07429269 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,06258467 0,07425661 ! female gonad development GO:0008585 71 37 0,000 0,06258467 0,07422056 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,06258467 0,07418455 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,06258467 0,07414857 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,06258467 0,07411263 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,06422153 0,07601414 ! meiosis I GO:0007127 74 38 0,000 0,06422153 0,07597733 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,06422153 0,07594056 ! organic anion transport GO:0015711 82 38 0,000 0,06422153 0,07590382 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,06422153 0,07586711 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,06422153 0,07583044 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,06422153 0,07579381 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,06422153 0,07575721 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,06422153 0,07572065 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,06422153 0,07568412 ! regulation of protein stability GO:0031647 77 38 0,000 0,06422153 0,07564763 ! spermatid development GO:0007286 69 38 0,000 0,06422153 0,07561118 ! glycogen metabolic process GO:0005977 63 38 0,000 0,06422153 0,07557475 ! pigment metabolic process GO:0042440 87 38 0,000 0,06422153 0,07553837 ! neural tube formation GO:0001841 79 38 0,000 0,06422153 0,07550202 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,06585557 0,07738584 ! negative regulation of binding GO:0051100 71 39 0,000 0,06585557 0,07734863 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,06585557 0,07731146 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,06585557 0,07727433 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,06585557 0,07723723 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,06585557 0,07720017 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,06585557 0,07716314 ! glucan metabolic process GO:0044042 64 39 0,000 0,06585557 0,07712615 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,0674868 0,07899869 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,0674868 0,07896085 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,0674868 0,07892305 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,0674868 0,07888529 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,0674868 0,07884756 ! lipid homeostasis GO:0055088 75 40 0,000 0,0674868 0,07880987 ! mismatch repair GO:0006298 58 40 0,000 0,0674868 0,07877222 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,0674868 0,0787346 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,0674868 0,07869702 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,0674868 0,07865947 ! RNA export from nucleus GO:0006405 61 41 0,000 0,06911523 0,08051908 ! mRNA catabolic process GO:0006402 79 41 0,000 0,06911523 0,0804807 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,06911523 0,08044236 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,06911523 0,08040405 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,06911523 0,08036578 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,06911523 0,08032755 ! gliogenesis GO:0042063 91 41 0,000 0,06911523 0,08028935 ! feeding behavior GO:0007631 69 41 0,000 0,06911523 0,08025119 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,06911523 0,08021307 ! mesenchymal cell development GO:0014031 94 41 0,000 0,06911523 0,08017498 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,06911523 0,08013693 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,06911523 0,08009892 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,06911523 0,08006094 ! spermatid differentiation GO:0048515 73 41 0,000 0,06911523 0,08002299 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,06911523 0,07998508 ! RNA modification GO:0009451 64 41 0,000 0,06911523 0,07994721 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,07074087 0,08178889 ! ear morphogenesis GO:0042471 64 42 0,000 0,07074087 0,08175021 ! organic ether metabolic process GO:0018904 59 42 0,000 0,07074087 0,08171155 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,07074087 0,08167294 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,07074087 0,08163436 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,07074087 0,08159581 ! regulation of protein secretion GO:0050708 77 42 0,000 0,07074087 0,08155731 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,07074087 0,08151884 ! cytokinesis GO:0000910 84 42 0,000 0,07074087 0,0814804 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,07074087 0,08144201 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,07236371 0,08327109 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,07236371 0,08323189 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,07236371 0,08319272 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,07236371 0,08315359 ! regulation of tube size GO:0035150 76 43 0,000 0,07236371 0,0831145 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,07236371 0,08307544 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,07236371 0,08303642 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,07236371 0,08299743 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,07236371 0,08295849 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,07236371 0,08291957 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,07236371 0,0828807 ! segmentation GO:0035282 78 43 0,000 0,07236371 0,08284186 ! ion transmembrane transport GO:0034220 79 43 0,000 0,07236371 0,08280306 ! neuron migration GO:0001764 85 43 0,000 0,07236371 0,08276429 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,07236371 0,08272557 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,07398376 0,08453804 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,07398376 0,08449851 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,07398376 0,08445903 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,07398376 0,08441958 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,07398376 0,08438017 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,07398376 0,08434079 ! striated muscle contraction GO:0006941 85 44 0,000 0,07398376 0,08430145 ! phagocytosis GO:0006909 105 44 0,000 0,07398376 0,08426215 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,07398376 0,08422289 ! double-strand break repair GO:0006302 85 44 0,000 0,07398376 0,08418366 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,07560103 0,08598385 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,07560103 0,08594384 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,07560103 0,08590386 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,07560103 0,08586393 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,07560103 0,08582403 ! biopolymer methylation GO:0043414 91 45 0,000 0,07560103 0,08578416 ! B cell differentiation GO:0030183 124 45 0,000 0,07560103 0,08574434 ! female gamete generation GO:0007292 71 45 0,000 0,07560103 0,08570455 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,07560103 0,0856648 ! polyol metabolic process GO:0019751 77 45 0,000 0,07560103 0,08562508 ! developmental growth GO:0048589 88 45 0,000 0,07560103 0,08558541 ! maintenance of location in cell GO:0051651 101 45 0,000 0,07560103 0,08554576 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,07721551 0,08733218 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,07721551 0,08729176 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,07721551 0,08725139 ! glycolysis GO:0006096 71 46 0,000 0,07721551 0,08721105 ! leukocyte migration GO:0050900 75 46 0,000 0,07721551 0,08717075 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,07721551 0,08713049 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,07721551 0,08709026 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,07721551 0,08705007 ! pigmentation GO:0043473 103 46 0,000 0,07721551 0,08700992 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,07721551 0,0869698 ! neural tube development GO:0021915 91 47 0,000 0,07882723 0,0887442 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,07882723 0,08870333 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,08043617 0,09047218 ! positive regulation of defense response GO:0031349 88 48 0,000 0,08043617 0,09043054 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,08043617 0,09038895 ! mitochondrial transport GO:0006839 94 48 0,000 0,08043617 0,09034739 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,08043617 0,09030587 ! cellular component disassembly GO:0022411 89 48 0,000 0,08043617 0,09026439 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,08043617 0,09022294 ! endosome transport GO:0016197 127 48 0,000 0,08043617 0,09018154 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,08043617 0,09014017 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,08043617 0,09009884 ! male sex differentiation GO:0046661 93 48 0,000 0,08043617 0,09005755 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,08043617 0,09001629 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,08043617 0,08997508 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,08043617 0,0899339 ! methylation GO:0032259 97 48 0,000 0,08043617 0,08989276 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,08204235 0,09164585 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,08204235 0,09160396 ! JNK cascade GO:0007254 106 49 0,000 0,08204235 0,09156211 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,08204235 0,0915203 ! protein homooligomerization GO:0051260 84 49 0,000 0,08204235 0,09147853 ! regulation of action potential GO:0001508 102 50 0,000 0,08364577 0,09322382 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,08364577 0,09318131 ! endocrine system development GO:0035270 109 50 0,000 0,08364577 0,09313884 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,08364577 0,09309641 ! regulation of ossification GO:0030278 123 50 0,000 0,08364577 0,09305402 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,08364577 0,09301166 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,08364577 0,09296935 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,08364577 0,09292707 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,08364577 0,09288483 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,08364577 0,09284263 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,08524644 0,09457631 ! peptide metabolic process GO:0006518 80 51 0,000 0,08524644 0,09453338 ! response to temperature stimulus GO:0009266 84 51 0,000 0,08524644 0,09449049 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,08524644 0,09444764 ! positive regulation of binding GO:0051099 88 52 0,000 0,08684435 0,09617441 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,08684435 0,09613083 ! Notch signaling pathway GO:0007219 111 52 0,000 0,08684435 0,09608729 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,08684435 0,0960438 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,08684435 0,09600034 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,08684435 0,09595692 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,08684435 0,09591354 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,08684435 0,0958702 ! histone modification GO:0016570 104 52 0,000 0,08684435 0,09582689 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,08684435 0,09578363 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,08684435 0,09574041 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,08684435 0,09569722 ! amino acid activation GO:0043038 98 52 0,000 0,08684435 0,09565408 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,08843952 0,09736716 ! inner ear development GO:0048839 89 53 0,000 0,08843952 0,0973233 ! chromatin remodeling GO:0006338 122 53 0,000 0,08843952 0,09727949 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,08843952 0,0972357 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,08843952 0,09719196 ! vesicle organization GO:0016050 127 53 0,000 0,08843952 0,09714826 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,08843952 0,0971046 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 0,000 0,08843952 0,09706098 ! synapse organization GO:0050808 102 53 0,000 0,08843952 0,09701739 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,09003194 0,09871994 ! regulation of translational initiation GO:0006446 87 54 0,000 0,09003194 0,09867565 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,09003194 0,0986314 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,09003194 0,09858719 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,09003194 0,09854302 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,09003194 0,09849889 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,09003194 0,0984548 ! membrane fusion GO:0006944 122 54 0,000 0,09003194 0,09841075 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,09003194 0,09836674 ! covalent chromatin modification GO:0016569 115 54 0,000 0,09003194 0,09832277 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,09003194 0,09827883 ! regulation of cell shape GO:0008360 142 54 0,000 0,09003194 0,09823494 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,09003194 0,09819108 ! RNA catabolic process GO:0006401 103 55 0,000 0,09162163 0,09988025 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,09162163 0,0998357 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,09162163 0,09979119 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,09162163 0,09974672 ! cell recognition GO:0008037 98 55 0,000 0,09162163 0,09970229 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,09162163 0,0996579 ! cell maturation GO:0048469 107 55 0,000 0,09162163 0,09961355 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,09162163 0,09956923 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,09162163 0,09952496 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,09320858 0,10120381 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,09320858 0,10115885 ! glucose catabolic process GO:0006007 88 56 0,000 0,09320858 0,10111393 ! RNA elongation GO:0006354 90 56 0,000 0,09320858 0,10106905 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,09479281 0,10274128 ! chloride transport GO:0006821 102 57 0,000 0,09479281 0,10269571 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,09479281 0,10265019 ! muscle fiber development GO:0048747 131 57 0,000 0,09479281 0,10260471 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,09479281 0,10255927 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,09479281 0,10251387 ! regulation of actin filament length GO:0030832 118 58 0,000 0,09637432 0,10417808 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,09637432 0,104132 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,09637432 0,10408596 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,09637432 0,10403997 ! gastrulation GO:0007369 122 58 0,000 0,09637432 0,10399402 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,09637432 0,1039481 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,09637432 0,10390223 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,09637432 0,1038564 ! maintenance of location GO:0051235 124 58 0,000 0,09637432 0,10381061 ! nuclear export GO:0051168 110 59 0,000 0,0979531 0,10546471 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,09952917 0,10711444 ! DNA catabolic process GO:0006308 94 60 0,000 0,09952917 0,10706727 ! regulation of endocytosis GO:0030100 104 60 0,000 0,09952917 0,10702015 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,09952917 0,10697306 ! adult behavior GO:0030534 104 60 0,000 0,09952917 0,10692602 ! kidney development GO:0001822 133 60 0,000 0,09952917 0,10687902 ! positive regulation of secretion GO:0051047 110 61 0,000 0,10110254 0,10852087 ! regulation of cellular component size GO:0032535 125 61 0,000 0,10110254 0,10847321 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,10110254 0,10842559 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,10110254 0,10837801 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,10110254 0,10833048 ! regulation of heart contraction GO:0008016 123 61 0,000 0,10110254 0,10828299 ! camera-type eye development GO:0043010 126 61 0,000 0,10110254 0,10823554 ! proton transport GO:0015992 117 61 0,000 0,10110254 0,10818813 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,10267319 0,10982076 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,10267319 0,1097727 ! tRNA processing GO:0008033 102 62 0,000 0,10267319 0,10972468 ! mesoderm development GO:0007498 128 63 0,000 0,10424115 0,11135161 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,10424115 0,11130294 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,10424115 0,11125432 ! hydrogen transport GO:0006818 121 64 0,000 0,10580641 0,11287557 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,10580641 0,1128263 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,10580641 0,11277708 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,10736898 0,11439268 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,10736898 0,11434282 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,10736898 0,114293 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,10736898 0,11424322 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,10736898 0,11419348 ! ear development GO:0043583 114 66 0,000 0,10892887 0,1158021 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,10892887 0,11575173 ! gonad development GO:0008406 115 66 0,000 0,10892887 0,1157014 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,11048607 0,11730442 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,11048607 0,11725346 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,11048607 0,11720255 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,11048607 0,11715168 ! secondary metabolic process GO:0019748 125 67 0,000 0,11048607 0,11710085 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,11204059 0,11869695 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,11204059 0,1186455 ! hexose catabolic process GO:0019320 113 68 0,000 0,11204059 0,11859409 ! extracellular matrix organization GO:0030198 146 68 0,000 0,11204059 0,11854273 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,11204059 0,11849141 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,11204059 0,11844014 ! regulation of lipase activity GO:0060191 137 68 0,000 0,11204059 0,11838891 ! adaptive immune response GO:0002250 126 68 0,000 0,11204059 0,11833773 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,11204059 0,11828659 ! negative regulation of cell size GO:0045792 144 69 0,000 0,11359244 0,11987315 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,11359244 0,11982139 ! negative regulation of protein kinase activity GO:0006469 144 69 0,000 0,11359244 0,11976968 ! lung development GO:0030324 165 69 0,000 0,11359244 0,11971801 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,11359244 0,11966638 ! urogenital system development GO:0001655 149 69 0,000 0,11359244 0,1196148 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,11359244 0,11956327 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,11359244 0,11951177 ! developmental maturation GO:0021700 128 69 0,000 0,11359244 0,11946033 ! single fertilization GO:0007338 83 69 0,000 0,11359244 0,11940892 ! negative regulation of kinase activity GO:0033673 145 70 0,000 0,11514163 0,12098537 ! cell redox homeostasis GO:0045454 114 70 0,000 0,11514163 0,12093336 ! germ cell development GO:0007281 133 70 0,000 0,11514163 0,12088139 ! activation of immune response GO:0002253 120 70 0,000 0,11514163 0,12082947 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,11514163 0,12077759 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,11668815 0,12234727 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,11668815 0,12229478 ! appendage morphogenesis GO:0035107 150 72 0,000 0,11823201 0,12385969 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 0,000 0,11823201 0,1238066 ! B cell activation GO:0042113 179 72 0,000 0,11823201 0,12375355 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,11823201 0,12370055 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,11823201 0,1236476 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,11823201 0,12359469 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,11823201 0,12354183 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,11823201 0,12348901 ! appendage development GO:0048736 151 73 0,000 0,11977321 0,12504528 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,11977321 0,12499186 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,11977321 0,12493849 ! acute inflammatory response GO:0002526 118 74 0,000 0,12131177 0,12648939 ! amino acid transport GO:0006865 148 74 0,000 0,12131177 0,12643543 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,12131177 0,12638151 ! negative regulation of transferase activity GO:0051348 155 74 0,000 0,12131177 0,12632764 ! respiratory system development GO:0060541 175 74 0,000 0,12131177 0,12627381 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,12284767 0,12781809 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,12284767 0,12776367 ! reproductive structure development GO:0048608 131 75 0,000 0,12284767 0,1277093 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,12284767 0,12765498 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,12284767 0,12760071 ! eye development GO:0001654 155 75 0,000 0,12284767 0,12754648 ! axon guidance GO:0007411 162 75 0,000 0,12284767 0,1274923 ! rhythmic process GO:0048511 142 75 0,000 0,12284767 0,12743816 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,12438094 0,12897395 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,12438094 0,12891924 ! regulation of blood pressure GO:0008217 134 76 0,000 0,12438094 0,12886456 ! amine catabolic process GO:0009310 136 77 0,000 0,12591157 0,13039507 ! neurotransmitter transport GO:0006836 142 77 0,000 0,12591157 0,13033982 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,12591157 0,13028461 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,12591157 0,13022945 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,12591157 0,13017434 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,12591157 0,13011928 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,12743957 0,13164265 ! antigen processing and presentation GO:0019882 117 78 0,000 0,12743957 0,13158701 ! fertilization GO:0009566 99 78 0,000 0,12743957 0,13153142 ! blood coagulation GO:0007596 151 79 0,000 0,12896494 0,13304955 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,12896494 0,13299339 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,12896494 0,13293727 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,12896494 0,13288121 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,12896494 0,13282519 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,13048768 0,13433688 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,13048768 0,13428029 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,13048768 0,13422375 ! meiosis GO:0007126 143 81 0,000 0,13200781 0,13573025 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,13200781 0,13567315 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,13200781 0,1356161 ! meiotic cell cycle GO:0051321 144 82 0,000 0,13352532 0,13711743 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,13504022 0,13861482 ! exocytosis GO:0006887 153 83 0,000 0,13504022 0,1385566 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,13504022 0,13849843 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,13504022 0,13844031 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,13504022 0,13838224 ! inorganic anion transport GO:0015698 156 83 0,000 0,13504022 0,13832422 ! response to nutrient GO:0007584 135 84 0,000 0,13655252 0,13981467 ! digestion GO:0007586 130 84 0,000 0,13655252 0,1397561 ! regulation of ligase activity GO:0051340 147 84 0,000 0,13655252 0,13969757 ! hemostasis GO:0007599 165 85 0,000 0,13806221 0,14118291 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,13806221 0,14112384 ! negative regulation of growth GO:0045926 168 85 0,000 0,13806221 0,14106482 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,13806221 0,14100585 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,13806221 0,14094692 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,13956931 0,14242599 ! regulation of lyase activity GO:0051339 169 86 0,000 0,13956931 0,14236652 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,14107381 0,14384112 ! mitochondrion organization GO:0007005 159 87 0,000 0,14107381 0,14378111 ! alcohol catabolic process GO:0046164 142 87 0,000 0,14107381 0,14372115 ! nucleosome assembly GO:0006334 126 87 0,000 0,14107381 0,14366124 ! regulation of protein transport GO:0051223 165 87 0,000 0,14107381 0,14360138 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,14257573 0,14506976 ! amine biosynthetic process GO:0009309 146 88 0,000 0,14257573 0,14500937 ! sensory perception of smell GO:0007608 117 88 0,000 0,14257573 0,14494902 ! chromatin assembly GO:0031497 128 88 0,000 0,14257573 0,14488873 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,14257573 0,14482848 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,14407506 0,14629068 ! regulation of DNA binding GO:0051101 167 89 0,000 0,14407506 0,1462299 ! tube morphogenesis GO:0035239 194 89 0,000 0,14407506 0,14616917 ! cellular defense response GO:0006968 123 89 0,000 0,14407506 0,1461085 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,14557181 0,14756512 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,14557181 0,14750391 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,14706599 0,14895614 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,14706599 0,14889441 ! gland development GO:0048732 220 91 0,000 0,14706599 0,14883273 ! defense response to bacterium GO:0042742 112 91 0,000 0,14706599 0,1487711 ! bone development GO:0060348 206 92 0,000 0,14855759 0,1502178 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,14855759 0,15015565 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,15004663 0,15159798 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,15004663 0,15153531 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,15004663 0,1514727 ! vitamin metabolic process GO:0006766 153 93 0,000 0,15004663 0,15141013 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,15153311 0,15284698 ! female pregnancy GO:0007565 166 94 0,000 0,15153311 0,1527839 ! sterol metabolic process GO:0016125 166 94 0,000 0,15153311 0,15272087 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,15153311 0,15265789 ! regulation of membrane potential GO:0042391 179 94 0,000 0,15153311 0,15259497 ! regulation of defense response GO:0031347 171 95 0,000 0,15301703 0,1540258 ! nucleosome organization GO:0034728 143 95 0,000 0,15301703 0,15396236 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,15301703 0,15389897 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,15301703 0,15383564 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,15301703 0,15377236 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,15301703 0,15370913 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,15301703 0,15364595 ! sex differentiation GO:0007548 171 96 0,000 0,1544984 0,15506967 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,15597721 0,15648966 ! transcription initiation GO:0006352 171 97 0,000 0,15597721 0,15642542 ! regulation of protein localization GO:0032880 188 97 0,000 0,15597721 0,15636124 ! forebrain development GO:0030900 210 98 0,000 0,15745349 0,1577764 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,15745349 0,15771171 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,16039841 0,16059562 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,16039841 0,16052983 ! positive regulation of immune response GO:0050778 175 100 0,000 0,16039841 0,1604641 ! hormone metabolic process GO:0042445 171 100 0,000 0,16039841 0,16039841