pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/787-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! localization within membrane GO:0051668 20 10 3,000 2,4E-09 5,774E-06 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 2,000 6,41E-08 7,711E-05 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 2,000 1,28E-07 1,027E-04 ! regulation of respiratory burst GO:0060263 11 7 2,000 2,238E-07 1,346E-04 ! negative regulation of endocytosis GO:0045806 11 8 2,000 3,575E-07 1,72E-04 ! ruffle organization GO:0031529 15 9 2,000 5,356E-07 2,148E-04 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 2,000 1,049E-06 3,606E-04 GO:0046579|positive regulation of Ras protein signal transduction, ! lamellipodium assembly GO:0030032 20 11 2,000 1,049E-06 3,155E-04 ! actin filament polymerization GO:0030041 24 13 2,000 1,814E-06 4,849E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 7,162E-06 1,723E-03 ! actin polymerization or depolymerization GO:0008154 48 20 2,000 7,162E-06 1,566E-03 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 2,000 9,648E-06 1,935E-03 ! vasculogenesis GO:0001570 46 25 2,000 1,435E-05 2,656E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,82E-05 3,128E-03 ! negative regulation of transport GO:0051051 153 84 3,000 1,987E-05 3,187E-03 ! glial cell fate commitment GO:0021781 13 5 1,000 3,506E-05 5,273E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,506E-05 4,963E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 3,506E-05 4,687E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 3,506E-05 4,44E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 5,253E-05 6,32E-03 ! cytokinesis GO:0000910 72 40 2,000 6,042E-05 6,923E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 7,346E-05 8,033E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 7,346E-05 7,684E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! vesicle fusion GO:0006906 17 7 1,000 7,346E-05 7,364E-03 ! lymph node development GO:0048535 10 7 1,000 7,346E-05 7,069E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 7,346E-05 6,798E-03 ! endosome to lysosome transport GO:0008333 11 7 1,000 7,346E-05 6,546E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 7,346E-05 6,312E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 7,346E-05 6,094E-03 ! cell growth GO:0016049 84 45 2,000 8,62E-05 6,913E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,782E-05 7,592E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 9,782E-05 7,355E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 9,782E-05 7,132E-03 ! blastocyst growth GO:0001832 19 8 1,000 9,782E-05 6,922E-03 ! protein homooligomerization GO:0051260 76 47 2,000 9,824E-05 6,753E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,046E-04 6,994E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,256E-04 8,169E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,256E-04 7,954E-03 GO:0010469|regulation of receptor activity, ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,256E-04 7,75E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,256E-04 7,556E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 1,256E-04 7,372E-03 GO:0002820|negative regulation of adaptive immune response, ! regulation of protein polymerization GO:0032271 103 53 2,000 1,408E-04 8,065E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,568E-04 8,775E-03 ! polyamine biosynthetic process GO:0006596 12 10 1,000 1,568E-04 8,576E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,568E-04 8,385E-03 ! negative regulation of immune effector process GO:0002698 20 10 1,000 1,568E-04 8,203E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 1,659E-04 8,494E-03 ! regulation of endocytosis GO:0030100 91 58 2,000 1,842E-04 9,233E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,915E-04 9,401E-03 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,915E-04 9,213E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of protein complex assembly GO:0043254 117 61 2,000 2,14E-04 0,01009493 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,295E-04 0,01061701 ! polyamine metabolic process GO:0006595 17 12 1,000 2,295E-04 0,01041669 ! gland morphogenesis GO:0022612 29 12 1,000 2,295E-04 0,01022379 ! actin filament organization GO:0007015 148 66 2,000 2,703E-04 0,01182236 ! cell projection assembly GO:0030031 120 66 2,000 2,703E-04 0,01161124 ! lipid localization GO:0010876 28 13 1,000 2,709E-04 0,01143281 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 2,709E-04 0,01123569 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,709E-04 0,01104525 ! chromatin silencing GO:0006342 26 13 1,000 2,709E-04 0,01086117 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 2,709E-04 0,01068311 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 2,825E-04 0,01096447 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 3,637E-04 0,01389074 ! regulation of vasodilation GO:0042312 26 15 1,000 3,637E-04 0,01367369 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 3,637E-04 0,01346333 ! regulation of vesicle-mediated transport GO:0060627 119 75 2,000 3,94E-04 0,01436362 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 4,152E-04 0,01490921 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 4,152E-04 0,01468996 ! activation of MAPKK activity GO:0000186 35 16 1,000 4,152E-04 0,01447706 ! lysosomal transport GO:0007041 26 16 1,000 4,152E-04 0,01427025 ! negative regulation of immune response GO:0050777 35 16 1,000 4,152E-04 0,01406926 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,152E-04 0,01387385 ! protein oligomerization GO:0051259 139 78 2,000 4,421E-04 0,01457213 ! regulation of peptidase activity GO:0052547 134 79 2,000 4,59E-04 0,01492265 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 4,59E-04 0,01472368 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 4,7E-04 0,01487803 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 4,7E-04 0,01468481 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,7E-04 0,01449654 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 4,939E-04 0,01504101 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 5,281E-04 0,01588157 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,281E-04 0,0156855 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,281E-04 0,01549422 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 5,895E-04 0,01708764 ! lipid phosphorylation GO:0046834 35 19 1,000 5,895E-04 0,01688421 ! regulation of protein transport GO:0051223 154 87 2,000 6,086E-04 0,01722785 GO:0070201|regulation of establishment of protein localization, ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,542E-04 0,01830169 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 6,542E-04 0,01809133 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 6,542E-04 0,01788574 ! regulation of cell killing GO:0031341 42 21 1,000 7,222E-04 0,01952259 ! hindlimb morphogenesis GO:0035137 43 21 1,000 7,222E-04 0,01930567 ! inactivation of MAPK activity GO:0000188 39 21 1,000 7,222E-04 0,01909352 ! regulation of vasoconstriction GO:0019229 39 21 1,000 7,222E-04 0,01888599 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 7,222E-04 0,01868291 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 7,392E-04 0,01891954 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 7,863E-04 0,01991476 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 7,934E-04 0,0198848 ! vacuolar transport GO:0007034 36 22 1,000 7,934E-04 0,0196798 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 7,934E-04 0,01947898 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,934E-04 0,01928223 ! sarcomere organization GO:0045214 30 22 1,000 7,934E-04 0,0190894 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,934E-04 0,0189004 ! regulation of protein localization GO:0032880 176 97 2,000 8,354E-04 0,01970465 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,679E-04 0,02027384 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 8,679E-04 0,0200789 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 8,679E-04 0,01988767 ! vesicle docking GO:0048278 47 24 1,000 9,457E-04 0,02146487 ! membrane depolarization GO:0051899 39 24 1,000 9,457E-04 0,02126426 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 9,457E-04 0,02106737 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,027E-03 0,02266168 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 1,027E-03 0,02245566 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,027E-03 0,02225336 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,111E-03 0,02386356 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,111E-03 0,02365237 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,111E-03 0,0234449 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 1,111E-03 0,02324103 ! positive regulation of nuclear division GO:0051785 40 26 1,000 1,111E-03 0,02304067 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 1,111E-03 0,02284375 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 1,289E-03 0,02627996 ! cell fate determination GO:0001709 60 29 1,000 1,383E-03 0,02795546 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,383E-03 0,0277225 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 1,383E-03 0,02749339 ! regulation of coagulation GO:0050818 46 29 1,000 1,383E-03 0,02726803 ! membrane docking GO:0022406 61 30 1,000 1,48E-03 0,02894306 ! myofibril assembly GO:0030239 47 30 1,000 1,48E-03 0,02870965 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,48E-03 0,02847997 ! cholesterol homeostasis GO:0042632 53 31 1,000 1,58E-03 0,03016585 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 1,000 1,58E-03 0,02992832 ! cholesterol transport GO:0030301 56 32 1,000 1,683E-03 0,03163572 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,683E-03 0,03139048 ! muscle cell development GO:0055001 49 32 1,000 1,683E-03 0,03114902 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 1,683E-03 0,03091124 ! hindbrain development GO:0030902 61 32 1,000 1,683E-03 0,03067706 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 1,683E-03 0,03044641 ! gene silencing GO:0016458 65 32 1,000 1,683E-03 0,03021919 ! sterol transport GO:0015918 57 33 1,000 1,789E-03 0,0318918 ! glial cell differentiation GO:0010001 63 34 1,000 1,899E-03 0,0335951 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 1,899E-03 0,03334988 ! negative regulation of secretion GO:0051048 63 35 1,000 2,012E-03 0,03507219 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 2,012E-03 0,03481987 ! neutral lipid metabolic process GO:0006638 50 35 1,000 2,012E-03 0,03457116 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 2,012E-03 0,03432597 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,012E-03 0,03408424 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 2,127E-03 0,03579338 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 2,246E-03 0,03753039 ! actomyosin structure organization GO:0031032 62 37 1,000 2,246E-03 0,03727156 ! tissue remodeling GO:0048771 76 37 1,000 2,246E-03 0,03701628 ! glycerol ether metabolic process GO:0006662 53 37 1,000 2,246E-03 0,03676447 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 2,246E-03 0,03651606 ! lipid homeostasis GO:0055088 67 38 1,000 2,368E-03 0,03823963 ! mammary gland development GO:0030879 86 39 1,000 2,493E-03 0,03998941 ! organic ether metabolic process GO:0018904 55 39 1,000 2,493E-03 0,03972457 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 2,493E-03 0,03946323 ! Rho protein signal transduction GO:0007266 74 39 1,000 2,493E-03 0,0392053 ! gliogenesis GO:0042063 88 41 1,000 2,752E-03 0,04299897 ! T cell differentiation GO:0030217 81 41 1,000 2,752E-03 0,04272156 ! keratinocyte differentiation GO:0030216 62 41 1,000 2,752E-03 0,0424477 ! regulation of T cell differentiation GO:0045580 70 41 1,000 2,752E-03 0,04217733 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 2,886E-03 0,04395259 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 2,886E-03 0,04367616 ! regulation of protein secretion GO:0050708 71 42 1,000 2,886E-03 0,04340319 ! striated muscle cell differentiation GO:0051146 82 43 1,000 3,023E-03 0,04518288 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 3,023E-03 0,04490398 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 3,164E-03 0,04669703 ! developmental growth GO:0048589 82 44 1,000 3,164E-03 0,0464123 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 3,307E-03 0,04821818 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 3,307E-03 0,04792771 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 3,307E-03 0,04764071 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 3,453E-03 0,04944979 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 3,453E-03 0,04915718 ! epidermal cell differentiation GO:0009913 68 46 1,000 3,453E-03 0,04886802 ! response to insulin stimulus GO:0032868 95 46 1,000 3,453E-03 0,04858225 ! positive regulation of protein transport GO:0051222 72 46 1,000 3,453E-03 0,04829979 ! response to calcium ion GO:0051592 81 47 1,000 3,602E-03 0,05009413 ! endosome transport GO:0016197 108 47 1,000 3,602E-03 0,04980623 ! regulation of adaptive immune response GO:0002819 84 47 1,000 3,602E-03 0,04952163 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 3,754E-03 0,05131894 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 4,067E-03 0,05528307 ! negative regulation of immune system process GO:0002683 95 50 1,000 4,067E-03 0,05497249 ! vesicle organization GO:0016050 107 51 1,000 4,228E-03 0,05682778 ! regulation of cell shape GO:0008360 125 51 1,000 4,228E-03 0,05651207 ! regulation of angiogenesis GO:0045765 114 52 1,000 4,392E-03 0,05837713 ! regulation of muscle contraction GO:0006937 81 52 1,000 4,392E-03 0,05805637 ! membrane fusion GO:0006944 110 52 1,000 4,392E-03 0,05773913 ! covalent chromatin modification GO:0016569 101 52 1,000 4,392E-03 0,05742533 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 4,392E-03 0,05711492 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 4,558E-03 0,05896419 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 4,558E-03 0,05864888 ! response to UV GO:0009411 104 53 1,000 4,558E-03 0,05833691 ! activation of phospholipase C activity GO:0007202 103 54 1,000 4,728E-03 0,06018722 GO:0010863|positive regulation of phospholipase C activity, ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 4,728E-03 0,05987045 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 4,9E-03 0,06172968 ! regulation of actin filament length GO:0030832 105 56 1,000 5,076E-03 0,06360554 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 5,254E-03 0,06549763 ! positive regulation of cell migration GO:0030335 126 57 1,000 5,254E-03 0,06516001 ! lipid modification GO:0030258 97 57 1,000 5,254E-03 0,06482586 ! regulation of phospholipase activity GO:0010517 106 57 1,000 5,254E-03 0,06449512 ! regulation of intracellular transport GO:0032386 101 57 1,000 5,254E-03 0,06416773 ! positive regulation of lipase activity GO:0060193 108 58 1,000 5,435E-03 0,06604384 ! regulation of cellular component size GO:0032535 109 59 1,000 5,619E-03 0,06793543 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 5,806E-03 0,06984213 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 5,806E-03 0,06949465 ! kidney development GO:0001822 122 60 1,000 5,806E-03 0,06915062 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 5,995E-03 0,07105655 ! regulation of mitosis GO:0007088 105 63 1,000 6,383E-03 0,07527852 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 6,383E-03 0,0749113 ! positive regulation of cell motion GO:0051272 146 64 1,000 6,581E-03 0,07685946 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 6,781E-03 0,07882104 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 7,191E-03 0,08318118 ! activation of MAPK activity GO:0000187 115 67 1,000 7,191E-03 0,08278318 ! homeostasis of number of cells GO:0048872 114 67 1,000 7,191E-03 0,08238898 ! positive regulation of T cell activation GO:0050870 109 67 1,000 7,191E-03 0,08199851 ! negative regulation of kinase activity GO:0033673 131 68 1,000 7,4E-03 0,08398329 ! regulation of lipase activity GO:0060191 130 68 1,000 7,4E-03 0,083589 ! urogenital system development GO:0001655 137 69 1,000 7,612E-03 0,0855785 ! appendage morphogenesis GO:0035107 135 70 1,000 7,826E-03 0,08757993 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 1,000 8,043E-03 0,08959301 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 8,043E-03 0,08918014 ! regulation of immune effector process GO:0002697 137 71 1,000 8,043E-03 0,08877105 ! regulation of caspase activity GO:0043281 122 72 1,000 8,263E-03 0,09078076 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 8,263E-03 0,09036812 ! negative regulation of transferase activity GO:0051348 140 72 1,000 8,263E-03 0,08995922 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 8,711E-03 0,09440612 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 8,711E-03 0,09398278 ! eye development GO:0001654 143 74 1,000 8,711E-03 0,09356321 ! lymphocyte differentiation GO:0030098 167 75 1,000 8,939E-03 0,09558393 ! regulation of actin filament-based process GO:0032970 152 77 1,000 9,402E-03 0,10009725 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 9,402E-03 0,09965629 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 9,428E-03 0,09948984 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 9,428E-03 0,09905539 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,428E-03 0,09862472 ! positive regulation of helicase activity GO:0051096 11 5 0,000 9,428E-03 0,09819777 ! neuron fate determination GO:0048664 7 5 0,000 9,428E-03 0,0977745 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,428E-03 0,09735487 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 9,428E-03 0,09693882 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 9,428E-03 0,09652632 ! polyol transport GO:0015791 12 5 0,000 9,428E-03 0,09611731 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 9,428E-03 0,09571175 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,428E-03 0,0953096 ! response to superoxide GO:0000303 10 5 0,000 9,428E-03 0,09491081 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,428E-03 0,09451535 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 9,428E-03 0,09412317 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 9,428E-03 0,09373423 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,428E-03 0,0933485 ! female meiosis GO:0007143 7 5 0,000 9,428E-03 0,09296592 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 9,428E-03 0,09258647 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,428E-03 0,0922101 ! cobalt ion transport GO:0006824 11 5 0,000 9,428E-03 0,09183678 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 9,428E-03 0,09146647 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 9,428E-03 0,09109914 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 9,428E-03 0,09073474 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,428E-03 0,09037325 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,428E-03 0,09001462 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 9,428E-03 0,08965883 ! embryonic camera-type eye development GO:0031076 10 5 0,000 9,428E-03 0,08930584 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,428E-03 0,08895563 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 9,428E-03 0,08860814 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 9,428E-03 0,08826336 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,428E-03 0,08792126 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,428E-03 0,08758179 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,428E-03 0,08724494 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 9,428E-03 0,08691067 ! negative chemotaxis GO:0050919 14 5 0,000 9,428E-03 0,08657895 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,428E-03 0,08624975 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,428E-03 0,08592305 ! sensory perception of bitter taste GO:0050913 7 5 0,000 9,428E-03 0,08559881 ! behavioral response to pain GO:0048266 9 5 0,000 9,428E-03 0,08527701 ! clathrin coat assembly GO:0048268 14 5 0,000 9,428E-03 0,08495762 ! Notch receptor processing GO:0007220 8 5 0,000 9,428E-03 0,08464061 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,428E-03 0,08432597 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,428E-03 0,08401365 ! micturition GO:0060073 9 5 0,000 9,428E-03 0,08370363 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,428E-03 0,0833959 ! copulation GO:0007620 9 5 0,000 9,428E-03 0,08309042 ! protein maturation by protein folding GO:0022417 13 5 0,000 9,428E-03 0,08278717 ! spermidine metabolic process GO:0008216 7 5 0,000 9,428E-03 0,08248613 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,428E-03 0,08218726 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,428E-03 0,08189056 ! apoptotic cell clearance GO:0043277 20 5 0,000 9,428E-03 0,08159599 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 9,428E-03 0,08130353 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,428E-03 0,08101316 ! grooming behavior GO:0007625 6 5 0,000 9,428E-03 0,08072486 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,428E-03 0,0804386 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 9,428E-03 0,08015436 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,428E-03 0,07987213 ! response to protozoan GO:0001562 10 5 0,000 9,428E-03 0,07959188 ! positive regulation of glycolysis GO:0045821 14 5 0,000 9,428E-03 0,07931358 ! lymph vessel development GO:0001945 10 5 0,000 9,428E-03 0,07903723 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 9,428E-03 0,07876279 ! endochondral ossification GO:0001958 16 5 0,000 9,428E-03 0,07849026 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,428E-03 0,0782196 ! parathyroid gland development GO:0060017 13 5 0,000 9,428E-03 0,07795081 ! anagen GO:0042640 6 5 0,000 9,428E-03 0,07768385 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,428E-03 0,07741872 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,428E-03 0,07715539 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 9,428E-03 0,07689385 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 9,428E-03 0,07663407 ! dorsal spinal cord development GO:0021516 7 5 0,000 9,428E-03 0,07637604 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 9,428E-03 0,07611975 ! sphingoid catabolic process GO:0046521 6 5 0,000 9,428E-03 0,07586517 ! skeletal myofibril assembly GO:0014866 10 5 0,000 9,428E-03 0,07561228 ! smooth muscle tissue development GO:0048745 28 5 0,000 9,428E-03 0,07536108 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,428E-03 0,07511154 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,428E-03 0,07486365 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,428E-03 0,07461738 ! cardiac muscle fiber development GO:0048739 10 5 0,000 9,428E-03 0,07437274 ! transepithelial chloride transport GO:0030321 9 5 0,000 9,428E-03 0,07412969 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,428E-03 0,07388822 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 9,428E-03 0,07364833 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 9,428E-03 0,07340998 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,428E-03 0,07317318 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,428E-03 0,07293789 ! histidine catabolic process GO:0006548 6 5 0,000 9,428E-03 0,07270412 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 9,428E-03 0,07247184 ! microvillus organization GO:0032528 7 5 0,000 9,428E-03 0,07224103 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 9,428E-03 0,0720117 ! L-serine biosynthetic process GO:0006564 6 5 0,000 9,428E-03 0,07178381 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,428E-03 0,07155736 ! tryptophan metabolic process GO:0006568 9 5 0,000 9,428E-03 0,07133234 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 9,428E-03 0,07110873 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,428E-03 0,07088651 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 9,428E-03 0,07066568 ! polyol catabolic process GO:0046174 7 5 0,000 9,428E-03 0,07044623 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 9,428E-03 0,07022813 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,428E-03 0,07001137 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,428E-03 0,06979595 ! muscle cell migration GO:0014812 8 5 0,000 9,428E-03 0,06958185 ! mitochondrial fission GO:0000266 8 5 0,000 9,428E-03 0,06936907 ! sister chromatid cohesion GO:0007062 12 5 0,000 9,428E-03 0,06915758 ! mRNA transcription GO:0009299 9 5 0,000 9,428E-03 0,06894737 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 9,428E-03 0,06873844 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 9,428E-03 0,06853077 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 9,428E-03 0,06832435 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,428E-03 0,06811917 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,428E-03 0,06791522 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,428E-03 0,06771249 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,428E-03 0,06751097 ! response to food GO:0032094 6 5 0,000 9,428E-03 0,06731064 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,428E-03 0,06711149 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,428E-03 0,06691352 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 9,428E-03 0,06671672 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,428E-03 0,06652107 ! paraxial mesoderm development GO:0048339 14 5 0,000 9,428E-03 0,06632656 ! forebrain neuron development GO:0021884 13 5 0,000 9,428E-03 0,06613319 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,428E-03 0,06594094 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 9,428E-03 0,06574981 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 9,428E-03 0,06555978 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,428E-03 0,06537085 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,428E-03 0,065183 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 9,428E-03 0,06499623 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,428E-03 0,06481053 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 9,428E-03 0,06462588 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 9,428E-03 0,06444229 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 9,428E-03 0,06425973 ! basic amino acid transport GO:0015802 11 5 0,000 9,428E-03 0,06407821 ! cellular glucose homeostasis GO:0001678 5 5 0,000 9,428E-03 0,0638977 ! early endosome to late endosome transport GO:0045022 12 5 0,000 9,428E-03 0,06371822 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,428E-03 0,06353973 ! depyrimidination GO:0045008 10 5 0,000 9,428E-03 0,06336225 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,428E-03 0,06318575 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,428E-03 0,06301024 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,428E-03 0,06283569 ! zinc ion homeostasis GO:0055069 8 5 0,000 9,428E-03 0,06266211 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 9,428E-03 0,06248949 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 9,428E-03 0,06231781 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,428E-03 0,06214708 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,428E-03 0,06197728 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,428E-03 0,0618084 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 9,428E-03 0,06164045 ! peptidyl-arginine modification GO:0018195 9 5 0,000 9,428E-03 0,0614734 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,428E-03 0,06130726 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,428E-03 0,06114201 ! response to arsenic GO:0046685 10 5 0,000 9,428E-03 0,06097765 ! mast cell degranulation GO:0043303 7 5 0,000 9,428E-03 0,06081417 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 9,428E-03 0,06065156 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 9,428E-03 0,06048983 ! response to cadmium ion GO:0046686 7 5 0,000 9,428E-03 0,06032895 ! bile acid biosynthetic process GO:0006699 6 5 0,000 9,428E-03 0,06016892 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 9,428E-03 0,06000975 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,428E-03 0,05985141 ! decidualization GO:0046697 11 5 0,000 9,428E-03 0,05969391 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 9,428E-03 0,05953723 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 9,428E-03 0,05938137 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,428E-03 0,05922633 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,428E-03 0,0590721 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 9,428E-03 0,05891866 ! base conversion or substitution editing GO:0016553 5 5 0,000 9,428E-03 0,05876602 ! neural tube patterning GO:0021532 7 5 0,000 9,428E-03 0,05861417 ! embryonic cleavage GO:0040016 6 5 0,000 9,428E-03 0,0584631 ! peroxisome fission GO:0016559 5 5 0,000 9,428E-03 0,05831281 ! histone demethylation GO:0016577 10 5 0,000 9,428E-03 0,05816329 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 9,428E-03 0,05801454 ! mitotic recombination GO:0006312 9 5 0,000 9,428E-03 0,05786654 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,428E-03 0,0577193 ! metaphase plate congression GO:0051310 7 5 0,000 9,428E-03 0,0575728 ! regulation of sterol transport GO:0032371 7 5 0,000 9,428E-03 0,05742705 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,428E-03 0,05728203 ! enteric nervous system development GO:0048484 8 5 0,000 9,428E-03 0,05713774 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 9,428E-03 0,05699418 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 9,428E-03 0,05685134 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 9,428E-03 0,05670921 ! muscle cell proliferation GO:0033002 11 5 0,000 9,428E-03 0,05656779 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,428E-03 0,05642708 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 9,428E-03 0,05628706 ! plasminogen activation GO:0031639 5 5 0,000 9,428E-03 0,05614773 ! B cell homeostasis GO:0001782 13 5 0,000 9,428E-03 0,0560091 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 9,428E-03 0,05587114 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,428E-03 0,05573387 ! metaphase GO:0051323 8 5 0,000 9,428E-03 0,05559727 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 9,428E-03 0,05546133 ! cellular response to nutrient GO:0031670 8 5 0,000 9,428E-03 0,05532606 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,428E-03 0,05519145 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,428E-03 0,05505749 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,428E-03 0,05492418 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 9,428E-03 0,05479151 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 9,428E-03 0,05465948 ! response to redox state GO:0051775 5 5 0,000 9,428E-03 0,05452809 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 9,428E-03 0,05439733 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,428E-03 0,05426719 ! regulation of telomerase activity GO:0051972 6 5 0,000 9,428E-03 0,05413767 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,428E-03 0,05400877 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 9,428E-03 0,05388049 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,428E-03 0,05375281 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 9,428E-03 0,05362573 ! striatum development GO:0021756 9 5 0,000 9,428E-03 0,05349926 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 9,428E-03 0,05337338 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 9,428E-03 0,05324809 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,428E-03 0,05312338 ! glial cell migration GO:0008347 11 5 0,000 9,428E-03 0,05299926 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,428E-03 0,05287572 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 9,428E-03 0,05275275 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 9,428E-03 0,05263036 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,428E-03 0,05250853 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,428E-03 0,05238726 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,428E-03 0,05226655 ! neuroprotection GO:0043526 6 5 0,000 9,428E-03 0,0521464 ! neural plate development GO:0001840 8 5 0,000 9,428E-03 0,0520268 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,428E-03 0,05190775 ! regulation of sensory perception GO:0051931 7 5 0,000 9,428E-03 0,05178923 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,428E-03 0,05167126 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,428E-03 0,05155383 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 9,428E-03 0,05143693 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 9,428E-03 0,05132055 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,428E-03 0,05120471 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,428E-03 0,05108938 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,428E-03 0,05097457 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,428E-03 0,05086028 ! spindle assembly GO:0051225 6 5 0,000 9,428E-03 0,0507465 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 9,428E-03 0,05063322 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,428E-03 0,05052046 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,428E-03 0,05040819 ! drug metabolic process GO:0017144 6 5 0,000 9,428E-03 0,05029642 ! stem cell division GO:0017145 11 5 0,000 9,428E-03 0,05018514 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,428E-03 0,05007436 ! organ regeneration GO:0031100 7 5 0,000 9,428E-03 0,04996406 ! carnitine metabolic process GO:0009437 7 5 0,000 9,428E-03 0,04985425 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 9,428E-03 0,04974492 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,428E-03 0,04963607 ! activation of protein kinase activity GO:0032147 147 79 1,000 9,877E-03 0,05188414 ! response to metal ion GO:0010038 140 80 1,000 0,01011757 0,05303456 ! muscle cell differentiation GO:0042692 159 80 1,000 0,01011757 0,05291927 ! T cell activation GO:0042110 168 81 1,000 0,0103612 0,05407605 ! response to hypoxia GO:0001666 171 81 1,000 0,0103612 0,053959 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01060744 0,05512201 ! response to oxygen levels GO:0070482 176 83 1,000 0,01085625 0,05629341 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01130305 0,05848418 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01130305 0,05835868 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01130305 0,05823371 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01130305 0,05810928 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01130305 0,05798538 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01130305 0,05786201 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01130305 0,05773916 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01130305 0,05761683 ! sleep GO:0030431 13 6 0,000 0,01130305 0,05749502 ! response to oxygen radical GO:0000305 11 6 0,000 0,01130305 0,05737372 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01130305 0,05725293 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01130305 0,05713265 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01130305 0,05701288 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01130305 0,0568936 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01130305 0,05677483 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01130305 0,05665655 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01130305 0,05653876 ! forebrain regionalization GO:0021871 8 6 0,000 0,01130305 0,05642146 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01130305 0,05630464 ! male meiosis GO:0007140 7 6 0,000 0,01130305 0,05618831 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01130305 0,05607246 ! response to zinc ion GO:0010043 9 6 0,000 0,01130305 0,05595708 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01130305 0,05584218 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01130305 0,05572775 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01130305 0,05561379 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01130305 0,05550029 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01130305 0,05538726 ! malate metabolic process GO:0006108 11 6 0,000 0,01130305 0,05527468 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01130305 0,05516256 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01130305 0,0550509 ! protein refolding GO:0042026 15 6 0,000 0,01130305 0,05493968 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01130305 0,05482892 ! opsonization GO:0008228 8 6 0,000 0,01130305 0,0547186 ! mating behavior GO:0007617 7 6 0,000 0,01130305 0,05460872 ! neuron remodeling GO:0016322 15 6 0,000 0,01130305 0,05449928 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01130305 0,05439029 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01130305 0,05428172 ! equilibrioception GO:0050957 14 6 0,000 0,01130305 0,05417359 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01130305 0,05406589 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01130305 0,05395862 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01130305 0,05385177 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01130305 0,05374534 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01130305 0,05363933 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01130305 0,05353375 ! toxin metabolic process GO:0009404 11 6 0,000 0,01130305 0,05342857 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01130305 0,05332381 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01130305 0,05321946 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01130305 0,05311551 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01130305 0,05301197 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01130305 0,05290884 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01130305 0,0528061 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01130305 0,05270377 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01130305 0,05260182 ! thymic T cell selection GO:0045061 12 6 0,000 0,01130305 0,05250028 ! protein lipoylation GO:0009249 10 6 0,000 0,01130305 0,05239912 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01130305 0,05229835 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01130305 0,05219797 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01130305 0,05209797 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01130305 0,05199836 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01130305 0,05189913 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01130305 0,05180027 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01130305 0,05170179 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01130305 0,05160369 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01130305 0,05150595 ! hyperosmotic response GO:0006972 9 6 0,000 0,01130305 0,05140859 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01130305 0,05131159 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01130305 0,05121496 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01130305 0,05111869 ! urea metabolic process GO:0019627 7 6 0,000 0,01130305 0,05102278 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01130305 0,05092723 ! neutrophil activation GO:0042119 8 6 0,000 0,01130305 0,05083204 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01130305 0,05073721 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01130305 0,05064272 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01130305 0,05054859 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01130305 0,05045481 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01130305 0,05036138 ! neuron apoptosis GO:0051402 9 6 0,000 0,01130305 0,05026829 ! nucleoside salvage GO:0043174 9 6 0,000 0,01130305 0,05017554 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01130305 0,05008314 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01130305 0,04999107 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01130305 0,04989934 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01130305 0,04980795 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01130305 0,0497169 ! carnitine transport GO:0015879 10 6 0,000 0,01130305 0,04962617 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01130305 0,04953578 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01130305 0,04944571 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01130305 0,04935598 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01130305 0,04926656 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01130305 0,04917747 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01130305 0,04908871 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01130305 0,04900026 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01130305 0,04891213 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01130305 0,04882431 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01130305 0,04873682 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01130305 0,04864963 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01130305 0,04856276 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01130305 0,04847619 ! neural nucleus development GO:0048857 14 6 0,000 0,01130305 0,04838993 ! response to UV-C GO:0010225 11 6 0,000 0,01130305 0,04830398 ! astrocyte development GO:0014002 15 6 0,000 0,01130305 0,04821834 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01130305 0,048133 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01130305 0,04804796 ! interaction with symbiont GO:0051702 13 6 0,000 0,01130305 0,04796321 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01130305 0,04787877 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01130305 0,04779463 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01130305 0,04771078 ! response to copper ion GO:0046688 10 6 0,000 0,01130305 0,04762722 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01130305 0,04754396 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01130305 0,04746098 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01130305 0,0473783 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01130305 0,0472959 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01130305 0,04721379 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01130305 0,04713196 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01130305 0,04705042 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01130305 0,04696916 ! hair follicle maturation GO:0048820 7 6 0,000 0,01130305 0,04688818 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01130305 0,04680747 ! Schwann cell development GO:0014044 15 6 0,000 0,01130305 0,04672705 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01130305 0,0466469 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01130305 0,04656703 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01130305 0,04648742 ! subpallium development GO:0021544 10 6 0,000 0,01130305 0,04640809 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01130305 0,04632903 ! histone ubiquitination GO:0016574 8 6 0,000 0,01130305 0,04625024 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01130305 0,04617172 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01130305 0,04609346 ! G2 phase GO:0051319 16 6 0,000 0,01130305 0,04601547 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01130305 0,04593774 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01130305 0,04586027 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01130305 0,04578307 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01130305 0,04570612 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01130305 0,04562943 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01130305 0,045553 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01130305 0,04547683 ! receptor internalization GO:0031623 10 6 0,000 0,01130305 0,04540091 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01130305 0,04532524 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01130305 0,04524982 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01130305 0,04517466 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01130305 0,04509974 ! protein deubiquitination GO:0016579 14 6 0,000 0,01130305 0,04502507 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01130305 0,04495065 ! protein destabilization GO:0031648 9 6 0,000 0,01130305 0,04487647 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01130305 0,04480254 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01130305 0,04472885 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01130305 0,04465541 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01130305 0,0445822 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01130305 0,04450924 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01130305 0,04443651 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01130305 0,04436402 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01130305 0,04429176 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01130305 0,04421974 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01130305 0,04414796 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01130305 0,04407641 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01130305 0,04400509 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01130305 0,04393399 ! catecholamine transport GO:0051937 9 6 0,000 0,01130305 0,04386313 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01130305 0,0437925 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01130305 0,04372209 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01130305 0,04365191 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01130305 0,04358196 ! maternal placenta development GO:0001893 12 6 0,000 0,01130305 0,04351223 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01130305 0,04344272 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01130305 0,04337343 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01130305 0,04330437 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01130305 0,04323552 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01130305 0,04316689 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01130305 0,04309848 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01136159 0,04325314 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 1,000 0,01161809 0,04415977 ! response to inorganic substance GO:0010035 153 86 1,000 0,01161809 0,04409012 ! tube morphogenesis GO:0035239 176 86 1,000 0,01161809 0,04402069 ! gland development GO:0048732 206 88 1,000 0,01213872 0,045921 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,01240282 0,04684644 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,01240282 0,04677302 ! ossification GO:0001503 188 90 1,000 0,01266943 0,04770368 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,01266943 0,04762915 ! bone development GO:0060348 189 91 1,000 0,01293855 0,04856496 ! tRNA transcription GO:0009304 14 7 0,000 0,01317465 0,04937416 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01317465 0,04929737 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01317465 0,04922082 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01317465 0,04914451 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01317465 0,04906844 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01317465 0,0489926 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01317465 0,04891699 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01317465 0,04884162 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01317465 0,04876648 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01317465 0,04869157 ! prostate gland development GO:0030850 13 7 0,000 0,01317465 0,04861689 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01317465 0,04854244 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01317465 0,04846821 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01317465 0,04839421 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01317465 0,04832044 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01317465 0,0482469 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01317465 0,04817357 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01317465 0,04810047 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01317465 0,04802759 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01317465 0,04795493 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01317465 0,04788249 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01317465 0,04781027 ! glycolipid transport GO:0046836 10 7 0,000 0,01317465 0,04773827 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01317465 0,04766648 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01317465 0,04759491 ! neuron adhesion GO:0007158 12 7 0,000 0,01317465 0,04752355 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01317465 0,04745241 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01317465 0,04738148 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01317465 0,04731076 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01317465 0,04724025 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01317465 0,04716996 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01317465 0,04709987 ! mRNA stabilization GO:0048255 18 7 0,000 0,01317465 0,04702999 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01317465 0,04696031 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01317465 0,04689084 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01317465 0,04682158 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01317465 0,04675252 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01317465 0,04668367 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01317465 0,04661502 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01317465 0,04654656 ! lipoprotein transport GO:0042953 14 7 0,000 0,01317465 0,04647831 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01317465 0,04641026 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01317465 0,04634241 ! rhythmic behavior GO:0007622 15 7 0,000 0,01317465 0,04627476 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01317465 0,0462073 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01317465 0,04614004 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01317465 0,04607298 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01317465 0,04600611 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01317465 0,04593944 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01317465 0,04587295 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01317465 0,04580666 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01317465 0,04574056 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01317465 0,04567466 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01317465 0,04560894 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01317465 0,04554341 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01317465 0,04547806 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01317465 0,04541291 ! spinal cord patterning GO:0021511 13 7 0,000 0,01317465 0,04534794 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01317465 0,04528316 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01317465 0,04521856 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01317465 0,04515415 ! adrenal gland development GO:0030325 17 7 0,000 0,01317465 0,04508992 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01317465 0,04502587 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01317465 0,044962 ! ovulation GO:0030728 9 7 0,000 0,01317465 0,04489832 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01317465 0,04483481 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01317465 0,04477148 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01317465 0,04470834 ! microtubule nucleation GO:0007020 20 7 0,000 0,01317465 0,04464537 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01317465 0,04458257 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01317465 0,04451996 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01317465 0,04445752 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01317465 0,04439525 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01317465 0,04433316 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01317465 0,04427124 ! galactose metabolic process GO:0006012 13 7 0,000 0,01317465 0,0442095 ! response to dietary excess GO:0002021 8 7 0,000 0,01317465 0,04414793 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01317465 0,04408652 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01317465 0,04402529 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01317465 0,04396423 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01317465 0,04390334 ! organ growth GO:0035265 15 7 0,000 0,01317465 0,04384262 ! purine salvage GO:0043101 10 7 0,000 0,01317465 0,04378206 ! nucleoside transport GO:0015858 8 7 0,000 0,01317465 0,04372167 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01317465 0,04366145 ! parturition GO:0007567 14 7 0,000 0,01317465 0,04360139 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01317465 0,0435415 ! rRNA modification GO:0000154 14 7 0,000 0,01317465 0,04348177 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01317465 0,04342221 ! spindle checkpoint GO:0031577 15 7 0,000 0,01317465 0,04336281 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01317465 0,04330357 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01317465 0,04324449 ! macrophage differentiation GO:0030225 11 7 0,000 0,01317465 0,04318557 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01317465 0,04312682 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01317465 0,04306822 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01317465 0,04300978 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01317465 0,04295151 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01317465 0,04289338 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01317465 0,04283542 ! fibrinolysis GO:0042730 10 7 0,000 0,01317465 0,04277761 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01317465 0,04271996 ! eating behavior GO:0042755 7 7 0,000 0,01317465 0,04266246 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01317465 0,04260512 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01317465 0,04254793 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01317465 0,0424909 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01317465 0,04243402 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01317465 0,04237729 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01317465 0,04232071 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01317465 0,04226428 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01317465 0,042208 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01317465 0,04215188 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01317465 0,0420959 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01317465 0,04204007 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01317465 0,04198439 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01317465 0,04192885 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01317465 0,04187346 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01317465 0,04181822 ! regulation of meiosis GO:0040020 12 7 0,000 0,01317465 0,04176312 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01317465 0,04170817 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01317465 0,04165336 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01317465 0,0415987 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01317465 0,04154418 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01317465 0,0414898 ! transcription termination GO:0006353 13 7 0,000 0,01317465 0,04143557 ! response to tumor cell GO:0002347 13 7 0,000 0,01317465 0,04138148 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01317465 0,04132752 ! anaphase GO:0051322 17 7 0,000 0,01317465 0,04127371 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01317465 0,04122004 ! axonal fasciculation GO:0007413 18 7 0,000 0,01317465 0,04116651 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01317465 0,04111311 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01317465 0,04105986 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01317465 0,04100674 ! diuresis GO:0030146 12 7 0,000 0,01317465 0,04095376 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01317465 0,04090092 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01317465 0,04084821 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01317465 0,04079564 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01317465 0,0407432 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01317465 0,0406909 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01317465 0,04063873 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01317465 0,0405867 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01317465 0,0405348 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01317465 0,04048303 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01317465 0,04043139 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01317465 0,04037989 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01317465 0,04032851 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01317465 0,04027727 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01317465 0,04022616 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01317465 0,04017517 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01317465 0,04012432 ! adult feeding behavior GO:0008343 9 7 0,000 0,01317465 0,04007359 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01317465 0,04002299 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01317465 0,03997252 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01317465 0,03992218 ! muscle adaptation GO:0043500 14 7 0,000 0,01317465 0,03987196 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01317465 0,03982187 ! retina homeostasis GO:0001895 12 7 0,000 0,01317465 0,03977191 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01317465 0,03972207 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01317465 0,03967235 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01317465 0,03962276 ! protein prenylation GO:0018342 18 7 0,000 0,01317465 0,0395733 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01317465 0,03952395 ! regulation of membrane potential GO:0042391 164 93 1,000 0,01348424 0,04040234 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,01348424 0,04035209 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,0137608 0,04112855 ! regulation of T cell activation GO:0050863 158 94 1,000 0,0137608 0,04107752 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01403982 0,0418585 ! forebrain development GO:0030900 188 95 1,000 0,01403982 0,04180669 ! leukocyte differentiation GO:0002521 202 96 1,000 0,01432129 0,04259213 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,01460521 0,04338287 ! response to virus GO:0009615 160 98 1,000 0,01489155 0,04417889 ! interphase GO:0051325 213 98 1,000 0,01489155 0,04412448 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01504277 0,04451772 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01504277 0,04446303 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01504277 0,04440847 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01504277 0,04435405 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01504277 0,04429976 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01504277 0,0442456 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01504277 0,04419158 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01504277 0,04413769 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01504277 0,04408393 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01504277 0,0440303 ! meiotic prophase I GO:0007128 13 8 0,000 0,01504277 0,0439768 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01504277 0,04392343 ! oligopeptide transport GO:0006857 15 8 0,000 0,01504277 0,04387019 ! UTP metabolic process GO:0046051 8 8 0,000 0,01504277 0,04381707 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01504277 0,04376409 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01504277 0,04371124 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01504277 0,04365851 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01504277 0,04360591 ! succinate metabolic process GO:0006105 14 8 0,000 0,01504277 0,04355343 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01504277 0,04350109 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01504277 0,04344886 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01504277 0,04339677 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01504277 0,04334479 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01504277 0,04329295 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01504277 0,04324122 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01504277 0,04318962 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01504277 0,04313814 ! reflex GO:0060004 16 8 0,000 0,01504277 0,04308679 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01504277 0,04303556 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01504277 0,04298445 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01504277 0,04293346 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01504277 0,04288259 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01504277 0,04283184 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01504277 0,04278121 ! pigment granule organization GO:0048753 16 8 0,000 0,01504277 0,0427307 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01504277 0,04268031 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01504277 0,04263004 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01504277 0,04257989 ! histidine metabolic process GO:0006547 16 8 0,000 0,01504277 0,04252985 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01504277 0,04247993 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01504277 0,04243013 ! glycine catabolic process GO:0006546 13 8 0,000 0,01504277 0,04238045 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01504277 0,04233088 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01504277 0,04228143 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01504277 0,04223209 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01504277 0,04218287 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01504277 0,04213376 ! melanin metabolic process GO:0006582 15 8 0,000 0,01504277 0,04208477 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01504277 0,04203589 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01504277 0,04198713 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01504277 0,04193847 ! macrophage activation GO:0042116 12 8 0,000 0,01504277 0,04188993 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01504277 0,04184151 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01504277 0,04179319 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01504277 0,04174499 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01504277 0,04169689 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01504277 0,04164891 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01504277 0,04160104 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01504277 0,04155328 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01504277 0,04150562 ! osteoblast development GO:0002076 16 8 0,000 0,01504277 0,04145808 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01504277 0,04141064 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01504277 0,04136332 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01504277 0,0413161 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01504277 0,04126899 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01504277 0,04122199 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01504277 0,04117509 ! response to UV-B GO:0010224 16 8 0,000 0,01504277 0,0411283 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01504277 0,04108162 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01504277 0,04103504 ! intermediate filament organization GO:0045109 12 8 0,000 0,01504277 0,04098857 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01504277 0,0409422 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01504277 0,04089594 ! cellular extravasation GO:0045123 12 8 0,000 0,01504277 0,04084978 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01504277 0,04080372 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01504277 0,04075777 ! response to antibiotic GO:0046677 11 8 0,000 0,01504277 0,04071193 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01504277 0,04066618 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01504277 0,04062054 ! DNA topological change GO:0006265 12 8 0,000 0,01504277 0,040575 ! response to tropane GO:0014073 15 8 0,000 0,01504277 0,04052957 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01504277 0,04048423 ! melanosome transport GO:0032402 13 8 0,000 0,01504277 0,040439 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01504277 0,04039387 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01504277 0,04034883 ! mast cell activation GO:0045576 14 8 0,000 0,01504277 0,0403039 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01504277 0,04025907 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01504277 0,04021434 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01504277 0,0401697 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01504277 0,04012517 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01504277 0,04008073 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01504277 0,0400364 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01504277 0,03999216 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01504277 0,03994802 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01504277 0,03990397 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01504277 0,03986003 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01504277 0,03981618 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01504277 0,03977242 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01504277 0,03972876 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01504277 0,0396852 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01504277 0,03964173 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01504277 0,03959836 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01504277 0,03955509 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01504277 0,0395119 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01504277 0,03946882 ! hormone catabolic process GO:0042447 17 8 0,000 0,01504277 0,03942582 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01504277 0,03938292 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01504277 0,03934011 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01504277 0,0392974 ! ATP catabolic process GO:0006200 11 8 0,000 0,01504277 0,03925478 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01504277 0,03921225 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01504277 0,03916981 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01504277 0,03912746 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01504277 0,03908521 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01504277 0,03904305 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01504277 0,03900097 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01504277 0,03895899 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01504277 0,0389171 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01504277 0,0388753 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01504277 0,03883359 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01504277 0,03879197 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01504277 0,03875043 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01504277 0,03870899 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01504277 0,03866763 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01504277 0,03862636 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01504277 0,03858519 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01504277 0,03854409 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,01518032 0,03885516 GO:0060538|skeletal muscle organ development, ! regulation of developmental growth GO:0048638 15 9 0,000 0,01690741 0,04322979 ! axon extension GO:0048675 15 9 0,000 0,01690741 0,0431839 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01690741 0,04313811 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01690741 0,04309241 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01690741 0,04304681 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01690741 0,04300131 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01690741 0,0429559 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01690741 0,04291059 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01690741 0,04286537 ! phosphate transport GO:0006817 19 9 0,000 0,01690741 0,04282025 ! reproductive behavior GO:0019098 19 9 0,000 0,01690741 0,04277522 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01690741 0,04273029 ! CTP metabolic process GO:0046036 9 9 0,000 0,01690741 0,04268545 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01690741 0,04264071 ! GTP metabolic process GO:0046039 9 9 0,000 0,01690741 0,04259606 ! RNA methylation GO:0001510 15 9 0,000 0,01690741 0,0425515 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01690741 0,04250704 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01690741 0,04246267 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01690741 0,04241839 ! artery development GO:0060840 24 9 0,000 0,01690741 0,0423742 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01690741 0,04233011 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01690741 0,04228611 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01690741 0,0422422 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01690741 0,04219838 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01690741 0,04215465 ! chemosensory behavior GO:0007635 20 9 0,000 0,01690741 0,04211101 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01690741 0,04206746 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01690741 0,042024 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01690741 0,04198064 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01690741 0,04193736 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01690741 0,04189417 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01690741 0,04185107 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01690741 0,04180805 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01690741 0,04176513 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01690741 0,04172229 ! protein targeting to ER GO:0045047 22 9 0,000 0,01690741 0,04167955 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01690741 0,04163689 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01690741 0,04159431 ! T cell selection GO:0045058 23 9 0,000 0,01690741 0,04155183 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01690741 0,04150943 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01690741 0,04146711 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01690741 0,04142488 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01690741 0,04138274 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01690741 0,04134069 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01690741 0,04129872 ! mannose metabolic process GO:0006013 13 9 0,000 0,01690741 0,04125683 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01690741 0,04121503 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01690741 0,04117332 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01690741 0,04113169 ! receptor clustering GO:0043113 18 9 0,000 0,01690741 0,04109014 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01690741 0,04104867 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01690741 0,0410073 ! retinol metabolic process GO:0042572 18 9 0,000 0,01690741 0,040966 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01690741 0,04092479 ! behavioral fear response GO:0001662 22 9 0,000 0,01690741 0,04088365 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01690741 0,04084261 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01690741 0,04080164 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01690741 0,04076076 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01690741 0,04071996 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01690741 0,04067924 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01690741 0,0406386 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01690741 0,04059804 ! segment specification GO:0007379 13 9 0,000 0,01690741 0,04055756 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01690741 0,04051717 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01690741 0,04047685 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01690741 0,04043662 ! response to amine stimulus GO:0014075 13 9 0,000 0,01690741 0,04039646 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01690741 0,04035639 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01690741 0,04031639 ! erythrocyte development GO:0048821 15 9 0,000 0,01690741 0,04027647 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01690741 0,04023663 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01690741 0,04019687 ! renal water homeostasis GO:0003091 14 9 0,000 0,01690741 0,04015719 ! postreplication repair GO:0006301 22 9 0,000 0,01690741 0,04011759 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01690741 0,04007807 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01690741 0,04003862 ! icosanoid secretion GO:0032309 15 9 0,000 0,01690741 0,03999925 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01690741 0,03995996 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01690741 0,03992074 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01690741 0,0398816 ! regulation of cell division GO:0051302 15 9 0,000 0,01690741 0,03984254 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01690741 0,03980356 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01690741 0,03976465 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01690741 0,03972582 ! sterol catabolic process GO:0016127 11 9 0,000 0,01690741 0,03968706 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01690741 0,03964838 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01690741 0,03960977 ! S phase GO:0051320 9 9 0,000 0,01690741 0,03957124 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01690741 0,03953279 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01690741 0,0394944 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01690741 0,0394561 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01690741 0,03941787 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01690741 0,03937971 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01690741 0,03934162 ! purine base metabolic process GO:0006144 21 9 0,000 0,01690741 0,03930361 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01690741 0,03926567 ! pigment granule transport GO:0051904 17 9 0,000 0,01690741 0,03922781 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01690741 0,03919002 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01690741 0,0391523 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01690741 0,03911465 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01690741 0,03907708 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01690741 0,03903957 ! mitochondrion localization GO:0051646 15 9 0,000 0,01690741 0,03900214 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01876859 0,04325405 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01876859 0,04321266 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01876859 0,04317134 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01876859 0,04313011 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01876859 0,04308896 ! synapsis GO:0007129 13 10 0,000 0,01876859 0,04304788 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01876859 0,04300688 ! N-glycan processing GO:0006491 20 10 0,000 0,01876859 0,04296596 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01876859 0,04292512 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01876859 0,04288435 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01876859 0,04284367 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01876859 0,04280306 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01876859 0,04276252 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01876859 0,04272207 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01876859 0,04268169 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01876859 0,04264138 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01876859 0,04260116 ! androgen metabolic process GO:0008209 17 10 0,000 0,01876859 0,042561 ! phospholipid efflux GO:0033700 16 10 0,000 0,01876859 0,04252093 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01876859 0,04248093 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01876859 0,042441 ! lung alveolus development GO:0048286 26 10 0,000 0,01876859 0,04240115 ! pathogenesis GO:0009405 13 10 0,000 0,01876859 0,04236137 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01876859 0,04232167 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01876859 0,04228205 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01876859 0,04224249 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01876859 0,04220301 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01876859 0,04216361 ! endoderm development GO:0007492 16 10 0,000 0,01876859 0,04212428 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01876859 0,04208502 ! arginine catabolic process GO:0006527 13 10 0,000 0,01876859 0,04204583 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01876859 0,04200672 ! proline metabolic process GO:0006560 13 10 0,000 0,01876859 0,04196768 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01876859 0,04192871 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01876859 0,04188982 ! V(D)J recombination GO:0033151 28 10 0,000 0,01876859 0,041851 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01876859 0,04181225 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01876859 0,04177357 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01876859 0,04173496 ! B cell proliferation GO:0042100 18 10 0,000 0,01876859 0,04169642 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01876859 0,04165796 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01876859 0,04161956 ! multicellular organism growth GO:0035264 18 10 0,000 0,01876859 0,04158124 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01876859 0,04154299 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01876859 0,0415048 ! epithelial cell development GO:0002064 20 10 0,000 0,01876859 0,04146669 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01876859 0,04142865 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01876859 0,04139067 ! macroautophagy GO:0016236 17 10 0,000 0,01876859 0,04135277 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01876859 0,04131494 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01876859 0,04127717 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01876859 0,04123948 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01876859 0,04120185 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01876859 0,04116429 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01876859 0,0411268 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01876859 0,04108938 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01876859 0,04105202 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01876859 0,04101474 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01876859 0,04097752 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01876859 0,04094037 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01876859 0,04090328 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01876859 0,04086627 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01876859 0,04082932 ! response to dsRNA GO:0043331 20 10 0,000 0,01876859 0,04079243 ! DNA ligation GO:0006266 19 10 0,000 0,01876859 0,04075562 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01876859 0,04071887 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01876859 0,04068219 ! melanosome localization GO:0032400 16 10 0,000 0,01876859 0,04064557 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01876859 0,04060902 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01876859 0,04057253 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01876859 0,04053611 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01876859 0,04049975 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01876859 0,04046346 ! mRNA cleavage GO:0006379 17 10 0,000 0,01876859 0,04042724 ! protein sumoylation GO:0016925 15 10 0,000 0,01876859 0,04039108 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01876859 0,04035498 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01876859 0,04031895 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01876859 0,04028298 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01876859 0,04024708 ! salivary gland development GO:0007431 27 10 0,000 0,01876859 0,04021124 ! prophase GO:0051324 15 10 0,000 0,01876859 0,04017547 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01876859 0,04013976 ! apical protein localization GO:0045176 15 10 0,000 0,01876859 0,04010411 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01876859 0,04006852 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01876859 0,040033 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01876859 0,03999754 ! midbrain development GO:0030901 13 10 0,000 0,01876859 0,03996215 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01876859 0,03992681 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01876859 0,03989154 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01876859 0,03985633 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01876859 0,03982119 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01876859 0,0397861 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01876859 0,03975108 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01876859 0,03971612 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01876859 0,03968122 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01876859 0,03964638 ! oocyte development GO:0048599 17 10 0,000 0,01876859 0,0396116 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01876859 0,03957688 ! blastocyst formation GO:0001825 17 10 0,000 0,01876859 0,03954223 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01876859 0,03950763 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01876859 0,0394731 ! activation of innate immune response GO:0002218 12 10 0,000 0,01876859 0,03943862 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01876859 0,03940421 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01876859 0,03936986 ! response to nicotine GO:0035094 20 10 0,000 0,01876859 0,03933556 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01876859 0,03930133 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01876859 0,03926715 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0206263 0,04311632 ! respiratory burst GO:0045730 17 11 0,000 0,0206263 0,04307889 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0206263 0,04304153 ! neuron fate specification GO:0048665 17 11 0,000 0,0206263 0,04300423 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0206263 0,042967 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0206263 0,04292983 ! thyroid gland development GO:0030878 26 11 0,000 0,0206263 0,04289273 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0206263 0,04285569 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0206263 0,04281871 ! response to pain GO:0048265 24 11 0,000 0,0206263 0,0427818 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0206263 0,04274495 ! T cell proliferation GO:0042098 26 11 0,000 0,0206263 0,04270816 ! blood vessel remodeling GO:0001974 29 11 0,000 0,0206263 0,04267144 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,0206263 0,04263478 ! bone resorption GO:0045453 16 11 0,000 0,0206263 0,04259818 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,0206263 0,04256165 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0206263 0,04252518 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0206263 0,04248877 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0206263 0,04245243 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0206263 0,04241614 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0206263 0,04237992 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0206263 0,04234376 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0206263 0,04230766 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0206263 0,04227162 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0206263 0,04223565 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,0206263 0,04219973 ! lipid digestion GO:0044241 18 11 0,000 0,0206263 0,04216388 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0206263 0,04212809 ! UV protection GO:0009650 19 11 0,000 0,0206263 0,04209235 ! adult heart development GO:0007512 14 11 0,000 0,0206263 0,04205668 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0206263 0,04202107 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0206263 0,04198552 ! temperature homeostasis GO:0001659 17 11 0,000 0,0206263 0,04195003 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0206263 0,0419146 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0206263 0,04187923 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0206263 0,04184392 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0206263 0,04180866 ! regulation of organ growth GO:0046620 13 11 0,000 0,0206263 0,04177347 ! pigment granule localization GO:0051875 20 11 0,000 0,0206263 0,04173834 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0206263 0,04170326 ! vasoconstriction GO:0042310 18 11 0,000 0,0206263 0,04166825 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0206263 0,04163329 ! embryonic axis specification GO:0000578 18 11 0,000 0,0206263 0,04159839 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0206263 0,04156356 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0206263 0,04152877 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0206263 0,04149405 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0206263 0,04145939 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0206263 0,04142478 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0206263 0,04139023 ! zymogen activation GO:0031638 15 11 0,000 0,0206263 0,04135574 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0206263 0,0413213 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0206263 0,04128693 ! nucleosome positioning GO:0016584 15 11 0,000 0,0206263 0,04125261 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0206263 0,04121834 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0206263 0,04118414 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0206263 0,04114999 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,0206263 0,04111589 ! acid secretion GO:0046717 18 11 0,000 0,0206263 0,04108186 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0206263 0,04104788 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0206263 0,04101395 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0206263 0,04098009 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0206263 0,04094627 ! oocyte differentiation GO:0009994 18 11 0,000 0,0206263 0,04091252 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0206263 0,04087882 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0206263 0,04084517 ! cholesterol efflux GO:0033344 19 11 0,000 0,0206263 0,04081158 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0206263 0,04077805 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0206263 0,04074457 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0206263 0,04071114 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0206263 0,04067777 ! embryonic gut development GO:0048566 15 11 0,000 0,0206263 0,04064446 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0206263 0,0406112 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0206263 0,04057799 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0206263 0,04054484 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0206263 0,04051174 ! defense response to fungus GO:0050832 13 11 0,000 0,0206263 0,0404787 ! developmental induction GO:0031128 19 11 0,000 0,0206263 0,04044571 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0206263 0,04041277 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0206263 0,04037989 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0206263 0,04034706 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0206263 0,04031429 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0206263 0,04028156 ! nucleus localization GO:0051647 19 11 0,000 0,0206263 0,04024889 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0206263 0,04021628 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02248056 0,04379614 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02248056 0,0437607 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02248056 0,04372533 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02248056 0,04369001 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02248056 0,04365475 ! virus-host interaction GO:0019048 29 12 0,000 0,02248056 0,04361954 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02248056 0,04358439 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02248056 0,0435493 ! cartilage condensation GO:0001502 20 12 0,000 0,02248056 0,04351426 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02248056 0,04347928 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02248056 0,04344436 ! protein complex disassembly GO:0043241 27 12 0,000 0,02248056 0,04340949 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02248056 0,04337468 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02248056 0,04333993 ! hippocampus development GO:0021766 26 12 0,000 0,02248056 0,04330523 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02248056 0,04327058 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02248056 0,043236 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02248056 0,04320146 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02248056 0,04316698 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02248056 0,04313256 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02248056 0,04309819 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02248056 0,04306388 ! drug transport GO:0015893 16 12 0,000 0,02248056 0,04302962 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02248056 0,04299541 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02248056 0,04296126 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02248056 0,04292717 ! focal adhesion formation GO:0048041 35 12 0,000 0,02248056 0,04289312 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02248056 0,04285914 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02248056 0,0428252 ! forebrain cell migration GO:0021885 21 12 0,000 0,02248056 0,04279132 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02248056 0,04275749 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02248056 0,04272372 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02248056 0,04269 ! entry into host cell GO:0030260 32 12 0,000 0,02248056 0,04265633 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02248056 0,04262272 ! monoamine transport GO:0015844 18 12 0,000 0,02248056 0,04258916 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02248056 0,04255565 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02248056 0,04252219 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02248056 0,04248879 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02248056 0,04245544 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02248056 0,04242214 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02248056 0,0423889 ! protein homotetramerization GO:0051289 21 12 0,000 0,02248056 0,0423557 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02248056 0,04232256 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02248056 0,04228947 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02248056 0,04225643 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02248056 0,04222344 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02248056 0,04219051 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02248056 0,04215762 ! cranial nerve development GO:0021545 20 12 0,000 0,02248056 0,04212479 ! fucose catabolic process GO:0019317 22 12 0,000 0,02248056 0,04209201 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02248056 0,04205928 ! histone acetylation GO:0016573 26 12 0,000 0,02248056 0,0420266 ! histone methylation GO:0016571 26 12 0,000 0,02248056 0,04199397 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02248056 0,04196139 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02248056 0,04192886 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02248056 0,04189638 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02248056 0,04186396 ! T cell homeostasis GO:0043029 25 12 0,000 0,02248056 0,04183158 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02248056 0,04179925 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02248056 0,04176697 ! spleen development GO:0048536 22 12 0,000 0,02248056 0,04173475 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02248056 0,04170257 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02248056 0,04167044 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02248056 0,04163836 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02248056 0,04160633 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02248056 0,04157435 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02248056 0,04154242 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02248056 0,04151054 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02248056 0,0414787 ! response to cold GO:0009409 17 12 0,000 0,02248056 0,04144692 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02248056 0,04141518 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02248056 0,0413835 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02433137 0,04475633 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02433137 0,04472214 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02433137 0,044688 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02433137 0,04465391 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02433137 0,04461988 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02433137 0,04458589 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02433137 0,04455196 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02433137 0,04451808 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02433137 0,04448425 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02433137 0,04445048 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02433137 0,04441675 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02433137 0,04438308 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02433137 0,04434945 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02433137 0,04431588 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02433137 0,04428236 ! methionine metabolic process GO:0006555 27 13 0,000 0,02433137 0,04424889 ! plasma membrane organization GO:0007009 24 13 0,000 0,02433137 0,04421547 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02433137 0,0441821 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02433137 0,04414878 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02433137 0,04411551 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02433137 0,04408229 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02433137 0,04404912 ! response to X-ray GO:0010165 25 13 0,000 0,02433137 0,044016 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02433137 0,04398293 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02433137 0,04394991 ! exocrine system development GO:0035272 32 13 0,000 0,02433137 0,04391694 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02433137 0,04388402 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02433137 0,04385114 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02433137 0,04381832 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02433137 0,04378555 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02433137 0,04375282 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02433137 0,04372015 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02433137 0,04368752 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02433137 0,04365494 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02433137 0,04362241 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02433137 0,04358993 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02433137 0,0435575 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02433137 0,04352511 ! ribosome assembly GO:0042255 17 13 0,000 0,02433137 0,04349278 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02433137 0,04346049 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02433137 0,04342825 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02433137 0,04339605 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02433137 0,04336391 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02433137 0,04333181 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02433137 0,04329976 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02433137 0,04326776 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02433137 0,0432358 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02433137 0,04320389 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02433137 0,04317203 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02433137 0,04314022 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02433137 0,04310845 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02433137 0,04307673 ! embryonic placenta development GO:0001892 23 13 0,000 0,02433137 0,04304506 ! insulin secretion GO:0030073 23 13 0,000 0,02433137 0,04301343 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02433137 0,04298185 ! acrosome reaction GO:0007340 18 13 0,000 0,02433137 0,04295031 ! rRNA transcription GO:0009303 25 14 0,000 0,02617874 0,04617745 ! lactation GO:0007595 26 14 0,000 0,02617874 0,04614362 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02617874 0,04610984 ! reproductive cellular process GO:0048610 20 14 0,000 0,02617874 0,04607611 ! tRNA modification GO:0006400 20 14 0,000 0,02617874 0,04604243 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02617874 0,04600879 ! regulation of S phase GO:0033261 23 14 0,000 0,02617874 0,04597521 ! water transport GO:0006833 21 14 0,000 0,02617874 0,04594168 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02617874 0,04590819 ! non-recombinational repair GO:0000726 25 14 0,000 0,02617874 0,04587476 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02617874 0,04584137 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02617874 0,04580803 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02617874 0,04577474 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02617874 0,0457415 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02617874 0,0457083 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02617874 0,04567516 ! palate development GO:0060021 31 14 0,000 0,02617874 0,04564206 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02617874 0,04560901 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02617874 0,04557601 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02617874 0,04554305 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02617874 0,04551014 ! arginine metabolic process GO:0006525 17 14 0,000 0,02617874 0,04547729 ! regulation of heart rate GO:0002027 24 14 0,000 0,02617874 0,04544447 ! organic alcohol transport GO:0015850 29 14 0,000 0,02617874 0,04541171 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02617874 0,04537899 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02617874 0,04534632 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02617874 0,0453137 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02617874 0,04528112 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02617874 0,04524859 ! L-amino acid transport GO:0015807 30 14 0,000 0,02617874 0,04521611 ! bone mineralization GO:0030282 17 14 0,000 0,02617874 0,04518367 ! stem cell development GO:0048864 43 14 0,000 0,02617874 0,04515128 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02617874 0,04511894 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02617874 0,04508664 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02617874 0,04505439 ! cerebellum development GO:0021549 21 14 0,000 0,02617874 0,04502219 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02617874 0,04499003 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02617874 0,04495792 ! response to gamma radiation GO:0010332 28 14 0,000 0,02617874 0,04492585 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02617874 0,04489383 ! cofactor transport GO:0051181 26 14 0,000 0,02617874 0,04486185 ! NADP metabolic process GO:0006739 24 14 0,000 0,02617874 0,04482992 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02617874 0,04479804 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02617874 0,0447662 ! intestinal absorption GO:0050892 25 14 0,000 0,02617874 0,0447344 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02617874 0,04470265 ! oxygen transport GO:0015671 21 14 0,000 0,02617874 0,04467095 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02617874 0,04463929 ! male genitalia development GO:0030539 24 14 0,000 0,02617874 0,04460768 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02617874 0,04457611 ! regulation of axon extension GO:0030516 37 14 0,000 0,02617874 0,04454458 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02617874 0,0445131 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02617874 0,04448167 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02802267 0,04758118 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02802267 0,04754763 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02802267 0,04751412 ! superoxide anion generation GO:0042554 20 15 0,000 0,02802267 0,04748066 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02802267 0,04744724 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02802267 0,04741388 ! copper ion transport GO:0006825 20 15 0,000 0,02802267 0,04738056 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02802267 0,04734729 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02802267 0,04731406 ! sulfate transport GO:0008272 23 15 0,000 0,02802267 0,04728088 ! response to cAMP GO:0051591 22 15 0,000 0,02802267 0,04724775 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02802267 0,04721466 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02802267 0,04718162 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02802267 0,04714863 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02802267 0,04711568 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02802267 0,04708278 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02802267 0,04704992 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02802267 0,04701711 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02802267 0,04698434 ! pituitary gland development GO:0021983 29 15 0,000 0,02802267 0,04695163 ! vesicle coating GO:0006901 33 15 0,000 0,02802267 0,04691895 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02802267 0,04688632 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02802267 0,04685374 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02802267 0,0468212 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02802267 0,04678871 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02802267 0,04675627 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02802267 0,04672386 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02802267 0,04669151 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02802267 0,04665919 ! histone deacetylation GO:0016575 20 15 0,000 0,02802267 0,04662693 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02802267 0,0465947 ! tissue regeneration GO:0042246 26 15 0,000 0,02802267 0,04656252 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02802267 0,04653039 ! water homeostasis GO:0030104 27 15 0,000 0,02802267 0,0464983 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02802267 0,04646625 ! muscle maintenance GO:0046716 26 15 0,000 0,02802267 0,04643425 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02802267 0,0464023 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02802267 0,04637038 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02802267 0,04633851 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02802267 0,04630669 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02802267 0,0462749 ! cell killing GO:0001906 29 15 0,000 0,02802267 0,04624317 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02802267 0,04621147 ! detection of bacterium GO:0016045 18 15 0,000 0,02802267 0,04617982 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02802267 0,04614821 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02802267 0,04611664 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02802267 0,04608512 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02802267 0,04605364 ! peptide hormone processing GO:0016486 23 15 0,000 0,02802267 0,04602221 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02986317 0,04901144 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02986317 0,04897803 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02986317 0,04894467 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02986317 0,04891135 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02986317 0,04887808 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02986317 0,04884485 ! bone remodeling GO:0046849 27 16 0,000 0,02986317 0,04881167 ! filopodium assembly GO:0046847 32 16 0,000 0,02986317 0,04877853 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02986317 0,04874544 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02986317 0,04871239 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02986317 0,04867939 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02986317 0,04864643 ! startle response GO:0001964 28 16 0,000 0,02986317 0,04861352 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02986317 0,04858065 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02986317 0,04854782 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02986317 0,04851504 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02986317 0,0484823 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02986317 0,04844961 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02986317 0,04841696 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02986317 0,04838436 ! response to osmotic stress GO:0006970 25 16 0,000 0,02986317 0,0483518 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02986317 0,04831928 GO:0031114|regulation of microtubule depolymerization, ! fructose metabolic process GO:0006000 25 16 0,000 0,02986317 0,04828681 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02986317 0,04825438 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02986317 0,048222 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02986317 0,04818966 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02986317 0,04815736 ! axon cargo transport GO:0008088 43 16 0,000 0,02986317 0,0481251 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02986317 0,04809289 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02986317 0,04806072 ! DNA replication initiation GO:0006270 27 16 0,000 0,02986317 0,04802859 ! neuron recognition GO:0008038 35 16 0,000 0,02986317 0,04799651 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02986317 0,04796447 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02986317 0,04793247 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02986317 0,04790052 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02986317 0,0478686 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02986317 0,04783673 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02986317 0,04780491 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02986317 0,04777312 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02986317 0,04774138 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02986317 0,04770968 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02986317 0,04767802 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02986317 0,0476464 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02986317 0,04761483 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02986317 0,0475833 ! defense response to virus GO:0051607 37 16 0,000 0,02986317 0,0475518 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03170024 0,05044364 ! metencephalon development GO:0022037 30 17 0,000 0,03170024 0,0504103 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03170024 0,050377 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03170024 0,05034375 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03170024 0,05031054 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03170024 0,05027738 ! signal complex assembly GO:0007172 41 17 0,000 0,03170024 0,05024425 ! endothelial cell migration GO:0043542 28 17 0,000 0,03170024 0,05021118 ! inositol metabolic process GO:0006020 28 17 0,000 0,03170024 0,05017814 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03170024 0,05014515 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03170024 0,05011221 ! glial cell development GO:0021782 27 17 0,000 0,03170024 0,0500793 ! limbic system development GO:0021761 36 17 0,000 0,03170024 0,05004644 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03170024 0,05001363 ! adult walking behavior GO:0007628 33 17 0,000 0,03170024 0,04998085 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03170024 0,04994812 ! heart looping GO:0001947 30 17 0,000 0,03170024 0,04991543 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03170024 0,04988279 ! myoblast differentiation GO:0045445 45 17 0,000 0,03170024 0,04985018 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03170024 0,04981762 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03170024 0,0497851 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03170024 0,04975263 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03170024 0,04972019 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03170024 0,0496878 ! glycine metabolic process GO:0006544 28 17 0,000 0,03170024 0,04965545 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03170024 0,04962315 ! NAD metabolic process GO:0019674 29 17 0,000 0,03170024 0,04959088 ! membrane budding GO:0006900 37 17 0,000 0,03170024 0,04955866 ! DNA integration GO:0015074 29 17 0,000 0,03170024 0,04952648 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03170024 0,04949434 ! regulation of protein binding GO:0043393 33 17 0,000 0,03170024 0,04946224 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03170024 0,04943019 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03170024 0,04939817 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03170024 0,0493662 ! genitalia development GO:0048806 30 17 0,000 0,03170024 0,04933427 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03170024 0,04930238 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03170024 0,04927053 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03170024 0,04923872 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03170024 0,04920695 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03170024 0,04917523 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03170024 0,04914354 ! steroid catabolic process GO:0006706 31 17 0,000 0,03170024 0,0491119 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03170024 0,0490803 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03170024 0,04904873 ! gas transport GO:0015669 25 17 0,000 0,03170024 0,04901721 ! organic cation transport GO:0015695 31 17 0,000 0,03170024 0,04898573 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03170024 0,04895429 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03170024 0,04892289 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03170024 0,04889152 ! microspike assembly GO:0030035 36 17 0,000 0,03170024 0,0488602 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03170024 0,04882892 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03170024 0,04879768 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0335339 0,05158731 ! neuron maturation GO:0042551 42 18 0,000 0,0335339 0,05155435 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0335339 0,05152143 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0335339 0,05148855 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0335339 0,05145571 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0335339 0,05142292 ! memory GO:0007613 31 18 0,000 0,0335339 0,05139016 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0335339 0,05135745 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0335339 0,05132478 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0335339 0,05129215 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0335339 0,05125957 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,0335339 0,05122702 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0335339 0,05119452 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0335339 0,05116205 ! response to retinoic acid GO:0032526 26 18 0,000 0,0335339 0,05112963 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0335339 0,05109725 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,0335339 0,05106491 ! response to fungus GO:0009620 21 18 0,000 0,0335339 0,05103261 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0335339 0,05100035 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0335339 0,05096814 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0335339 0,05093596 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0335339 0,05090382 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0335339 0,05087173 ! vitamin transport GO:0051180 27 18 0,000 0,0335339 0,05083967 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0335339 0,05080766 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0335339 0,05077568 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0335339 0,05074375 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0335339 0,05071185 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,0335339 0,05068 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0335339 0,05064818 ! nerve development GO:0021675 28 18 0,000 0,0335339 0,05061641 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0335339 0,05058468 ! protein secretion GO:0009306 39 19 0,000 0,03536414 0,05331211 ! positive regulation of translation GO:0045727 30 19 0,000 0,03536414 0,05327873 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03536414 0,05324539 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03536414 0,05321209 ! skin development GO:0043588 36 19 0,000 0,03536414 0,05317883 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03536414 0,05314562 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03536414 0,05311244 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03536414 0,05307931 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03536414 0,05304622 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03536414 0,05301316 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03536414 0,05298016 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03536414 0,05294719 ! cerebral cortex development GO:0021987 36 19 0,000 0,03536414 0,05291426 ! pigmentation during development GO:0048066 41 19 0,000 0,03536414 0,05288137 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03536414 0,05284853 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03536414 0,05281572 ! heme metabolic process GO:0042168 36 19 0,000 0,03536414 0,05278296 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03536414 0,05275024 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03536414 0,05271755 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03536414 0,05268491 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03536414 0,05265231 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03536414 0,05261975 ! peptide cross-linking GO:0018149 37 19 0,000 0,03536414 0,05258722 ! protein export from nucleus GO:0006611 36 19 0,000 0,03536414 0,05255474 ! heart process GO:0003015 30 19 0,000 0,03536414 0,0525223 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03536414 0,0524899 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03536414 0,05245754 ! visual learning GO:0008542 36 19 0,000 0,03536414 0,05242522 ! cellular pigmentation GO:0033059 36 19 0,000 0,03536414 0,05239294 ! G1 phase GO:0051318 40 19 0,000 0,03536414 0,0523607 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03536414 0,05232849 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03536414 0,05229633 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03536414 0,05226421 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03536414 0,05223212 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03536414 0,05220008 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03536414 0,05216807 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03536414 0,05213611 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03536414 0,05210418 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03536414 0,05207229 ! cilium assembly GO:0042384 37 19 0,000 0,03536414 0,05204045 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03536414 0,05200864 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03719098 0,05466189 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03719098 0,05462852 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03719098 0,05459518 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03719098 0,05456189 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03719098 0,05452865 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03719098 0,05449544 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03719098 0,05446227 ! response to vitamin GO:0033273 31 20 0,000 0,03719098 0,05442914 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03719098 0,05439605 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03719098 0,05436301 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03719098 0,05433 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03719098 0,05429703 ! response to alkaloid GO:0043279 38 20 0,000 0,03719098 0,0542641 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03719098 0,05423122 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03719098 0,05419837 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03719098 0,05416556 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03719098 0,05413279 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03719098 0,05410007 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03719098 0,05406738 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03719098 0,05403473 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03719098 0,05400212 ! body fluid secretion GO:0007589 31 20 0,000 0,03719098 0,05396955 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03719098 0,05393701 ! peptide secretion GO:0002790 35 20 0,000 0,03719098 0,05390452 ! stem cell differentiation GO:0048863 53 20 0,000 0,03719098 0,05387207 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03719098 0,05383966 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03719098 0,05380728 ! sensory perception of pain GO:0019233 30 20 0,000 0,03719098 0,05377494 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03719098 0,05374265 ! diencephalon development GO:0021536 34 20 0,000 0,03719098 0,05371039 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03719098 0,05367817 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03719098 0,05364599 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03719098 0,05361385 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03719098 0,05358174 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03719098 0,05354968 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03719098 0,05351765 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03719098 0,05348566 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03719098 0,05345371 ! regulation of glucose import GO:0046324 29 20 0,000 0,03719098 0,0534218 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03719098 0,05338992 ! actin filament-based movement GO:0030048 43 20 0,000 0,03719098 0,05335808 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03719098 0,05332629 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03719098 0,05329453 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03719098 0,0532628 ! negative regulation of translation GO:0017148 29 20 0,000 0,03719098 0,05323112 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03719098 0,05319947 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03719098 0,05316786 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03901443 0,05574151 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03901443 0,05570843 ! hormone secretion GO:0046879 38 21 0,000 0,03901443 0,05567539 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03901443 0,05564239 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03901443 0,05560942 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03901443 0,0555765 ! axis specification GO:0009798 38 21 0,000 0,03901443 0,05554361 ! ovarian follicle development GO:0001541 35 21 0,000 0,03901443 0,05551077 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03901443 0,05547796 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03901443 0,05544519 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03901443 0,05541246 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03901443 0,05537977 ! cell aging GO:0007569 44 21 0,000 0,03901443 0,05534712 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03901443 0,0553145 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03901443 0,05528192 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03901443 0,05524939 ! cytolysis GO:0019835 24 21 0,000 0,03901443 0,05521689 ! vasodilation GO:0042311 39 21 0,000 0,03901443 0,05518443 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03901443 0,055152 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03901443 0,05511962 ! oogenesis GO:0048477 36 21 0,000 0,03901443 0,05508727 ! DNA modification GO:0006304 34 21 0,000 0,03901443 0,05505496 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03901443 0,05502269 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03901443 0,05499046 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03901443 0,05495826 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03901443 0,0549261 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03901443 0,05489398 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03901443 0,0548619 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03901443 0,05482985 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03901443 0,05479784 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03901443 0,05476587 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03901443 0,05473394 ! collagen catabolic process GO:0030574 28 21 0,000 0,03901443 0,05470204 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03901443 0,05467018 ! gut development GO:0048565 39 21 0,000 0,03901443 0,05463836 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04083447 0,05715401 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04083447 0,05712078 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04083447 0,05708759 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04083447 0,05705444 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04083447 0,05702133 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04083447 0,05698825 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04083447 0,05695521 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04083447 0,05692222 ! regeneration GO:0031099 41 22 0,000 0,04083447 0,05688926 ! keratinization GO:0031424 28 22 0,000 0,04083447 0,05685633 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04083447 0,05682345 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04083447 0,0567906 ! sensory perception of taste GO:0050909 28 22 0,000 0,04083447 0,0567578 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04083447 0,05672503 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04083447 0,05669229 ! lysosome organization GO:0007040 41 22 0,000 0,04083447 0,0566596 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04083447 0,05662694 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04083447 0,05659432 ! fucose metabolic process GO:0006004 39 22 0,000 0,04083447 0,05656174 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04083447 0,0565292 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04083447 0,05649669 ! ureteric bud development GO:0001657 43 22 0,000 0,04083447 0,05646422 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04083447 0,05643179 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04083447 0,05639939 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04083447 0,05636704 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04083447 0,05633472 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04083447 0,05630243 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04083447 0,05627019 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04083447 0,05623798 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04083447 0,0562058 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04083447 0,05617367 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04083447 0,05614157 ! protein stabilization GO:0050821 39 22 0,000 0,04083447 0,05610951 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04265114 0,05857228 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04265114 0,05853887 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04265114 0,05850549 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04265114 0,05847216 ! gluconeogenesis GO:0006094 33 23 0,000 0,04265114 0,05843886 ! viral genome replication GO:0019079 41 23 0,000 0,04265114 0,0584056 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04265114 0,05837237 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04265114 0,05833919 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04265114 0,05830604 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04265114 0,05827293 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04265114 0,05823986 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04265114 0,05820682 ! visual behavior GO:0007632 42 23 0,000 0,04265114 0,05817383 ! response to ethanol GO:0045471 46 23 0,000 0,04265114 0,05814087 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04265114 0,05810795 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04265114 0,05807506 ! peroxisome organization GO:0007031 37 23 0,000 0,04265114 0,05804221 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04265114 0,0580094 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04265114 0,05797663 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04265114 0,05794389 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04265114 0,05791119 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,04265114 0,05787853 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04265114 0,0578459 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04265114 0,05781331 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04265114 0,05778076 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04265114 0,05774825 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04265114 0,05771577 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04265114 0,05768332 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04265114 0,05765092 ! fatty acid transport GO:0015908 44 23 0,000 0,04265114 0,05761855 ! platelet activation GO:0030168 37 23 0,000 0,04265114 0,05758621 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04265114 0,05755392 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04265114 0,05752165 ! hormone transport GO:0009914 40 23 0,000 0,04265114 0,05748943 ! cell-cell recognition GO:0009988 25 23 0,000 0,04265114 0,05745724 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04265114 0,05742509 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04265114 0,05739297 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04265114 0,05736089 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04265114 0,05732884 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04265114 0,05729684 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04446442 0,05969943 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04446442 0,05966614 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04446442 0,05963288 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,04446442 0,05959966 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04446442 0,05956647 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04446442 0,05953333 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04446442 0,05950022 ! spinal cord development GO:0021510 47 24 0,000 0,04446442 0,05946714 ! vacuole organization GO:0007033 43 24 0,000 0,04446442 0,0594341 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04446442 0,0594011 ! digestive system process GO:0022600 39 24 0,000 0,04446442 0,05936814 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04446442 0,05933521 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04446442 0,05930232 ! regulation of behavior GO:0050795 43 24 0,000 0,04446442 0,05926947 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04446442 0,05923665 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04446442 0,05920387 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04446442 0,05917112 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04446442 0,05913841 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04446442 0,05910574 ! pallium development GO:0021543 49 24 0,000 0,04446442 0,0590731 ! pentose metabolic process GO:0019321 35 24 0,000 0,04446442 0,0590405 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04446442 0,05900794 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04446442 0,05897541 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04446442 0,05894291 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04446442 0,05891046 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04446442 0,05887803 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04446442 0,05884565 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04446442 0,0588133 ! regulation of amine transport GO:0051952 40 24 0,000 0,04446442 0,05878098 ! protein tetramerization GO:0051262 52 24 0,000 0,04446442 0,0587487 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04627432 0,06110649 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,04627432 0,06107297 ! myelination GO:0042552 45 25 0,000 0,04627432 0,06103949 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04627432 0,06100604 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04627432 0,06097263 ! phototransduction GO:0007602 33 25 0,000 0,04627432 0,06093926 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,04627432 0,06090592 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,04627432 0,06087262 ! sperm motility GO:0030317 31 25 0,000 0,04627432 0,06083936 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,04627432 0,06080613 ! receptor metabolic process GO:0043112 46 25 0,000 0,04627432 0,06077294 ! chromosome condensation GO:0030261 45 25 0,000 0,04627432 0,06073978 ! response to starvation GO:0042594 42 25 0,000 0,04627432 0,06070666 ! osteoblast differentiation GO:0001649 60 25 0,000 0,04627432 0,06067358 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,04627432 0,06064054 ! neural crest cell development GO:0014032 54 25 0,000 0,04627432 0,06060752 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04627432 0,06057455 ! negative regulation of cell development GO:0010721 73 25 0,000 0,04627432 0,06054161 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04627432 0,06050871 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04627432 0,06047584 ! interaction with host GO:0051701 62 25 0,000 0,04627432 0,06044301 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04627432 0,06041021 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04627432 0,06037745 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04627432 0,06034473 ! immunoglobulin production GO:0002377 55 25 0,000 0,04627432 0,06031204 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04627432 0,06027938 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04627432 0,06024677 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,04627432 0,06021418 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04627432 0,06018163 ! telomere organization GO:0032200 43 25 0,000 0,04627432 0,06014912 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04627432 0,06011664 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04627432 0,0600842 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04808086 0,0623962 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04808086 0,06236256 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04808086 0,06232896 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04808086 0,0622954 ! initiation of viral infection GO:0019059 57 26 0,000 0,04808086 0,06226187 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04808086 0,06222838 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04808086 0,06219492 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04808086 0,0621615 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04808086 0,06212812 ! molting cycle process GO:0022404 50 26 0,000 0,04808086 0,06209477 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04808086 0,06206146 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04808086 0,06202818 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04808086 0,06199494 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04808086 0,06196173 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,04808086 0,06192856 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04808086 0,06189543 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04808086 0,06186233 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04808086 0,06182927 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04808086 0,06179624 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04808086 0,06176324 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04808086 0,06173029 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,04808086 0,06169736 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04808086 0,06166448 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04808086 0,06163162 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04808086 0,0615988 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04808086 0,06156602 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,04988404 0,06384096 ! neuron fate commitment GO:0048663 48 27 0,000 0,04988404 0,06380702 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04988404 0,06377311 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04988404 0,06373925 ! iron ion transport GO:0006826 59 27 0,000 0,04988404 0,06370541 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04988404 0,06367162 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04988404 0,06363786 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04988404 0,06360413 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04988404 0,06357044 ! fat cell differentiation GO:0045444 50 27 0,000 0,04988404 0,06353679 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04988404 0,06350317 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04988404 0,06346959 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04988404 0,06343605 ! autophagy GO:0006914 41 27 0,000 0,04988404 0,06340253 ! male gonad development GO:0008584 44 27 0,000 0,04988404 0,06336906 ! response to toxin GO:0009636 47 27 0,000 0,04988404 0,06333562 ! primary neural tube formation GO:0014020 51 27 0,000 0,04988404 0,06330221 ! base-excision repair GO:0006284 41 27 0,000 0,04988404 0,06326884 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04988404 0,06323551 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04988404 0,06320221 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04988404 0,06316895 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04988404 0,06313572 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04988404 0,06310252 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04988404 0,06306936 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04988404 0,06303624 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04988404 0,06300315 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05168386 0,06524206 ! circadian rhythm GO:0007623 50 28 0,000 0,05168386 0,06520785 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05168386 0,06517367 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05168386 0,06513953 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05168386 0,06510543 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05168386 0,06507136 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05168386 0,06503733 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05168386 0,06500333 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05168386 0,06496937 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05168386 0,06493544 ! synaptogenesis GO:0007416 42 28 0,000 0,05168386 0,06490155 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05168386 0,06486769 ! lipid oxidation GO:0034440 43 28 0,000 0,05168386 0,06483387 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05168386 0,06480009 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05168386 0,06476634 ! translational initiation GO:0006413 65 29 0,000 0,05348033 0,06698265 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,05348033 0,0669478 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,05348033 0,06691299 ! regulation of pH GO:0006885 43 29 0,000 0,05348033 0,06687821 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,05348033 0,06684347 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,05348033 0,06680876 ! catechol metabolic process GO:0009712 54 29 0,000 0,05348033 0,06677409 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,05348033 0,06673946 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,05348033 0,06670486 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,05348033 0,0666703 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,05348033 0,06663577 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,05348033 0,06660128 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,05348033 0,06656683 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,05348033 0,06653241 ! detection of light stimulus GO:0009583 38 29 0,000 0,05348033 0,06649802 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,05348033 0,06646368 ! tissue homeostasis GO:0001894 48 29 0,000 0,05348033 0,06642936 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,05527346 0,06862123 ! zinc ion transport GO:0006829 45 30 0,000 0,05527346 0,06858584 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,05527346 0,06855049 ! cell junction assembly GO:0034329 78 30 0,000 0,05527346 0,06851517 ! regulation of innate immune response GO:0045088 51 30 0,000 0,05527346 0,06847989 ! acute-phase response GO:0006953 49 30 0,000 0,05527346 0,06844464 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,05527346 0,06840944 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,05527346 0,06837426 ! phospholipid transport GO:0015914 51 30 0,000 0,05527346 0,06833913 ! ensheathment of neurons GO:0007272 57 30 0,000 0,05527346 0,06830403 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,05527346 0,06826896 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,05527346 0,06823394 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,05527346 0,06819894 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,05527346 0,06816399 ! eye morphogenesis GO:0048592 60 30 0,000 0,05527346 0,06812907 ! regulation of B cell activation GO:0050864 50 30 0,000 0,05527346 0,06809418 ! response to heat GO:0009408 50 30 0,000 0,05527346 0,06805934 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05706325 0,0702272 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05706325 0,0701913 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05706325 0,07015543 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05706325 0,0701196 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05706325 0,07008381 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05706325 0,07004805 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05706325 0,07001233 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05706325 0,06997664 ! ovulation cycle process GO:0022602 49 31 0,000 0,05706325 0,069941 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05706325 0,06990539 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,05706325 0,06986981 ! peptide transport GO:0015833 55 31 0,000 0,05706325 0,06983427 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05706325 0,06979877 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05706325 0,0697633 ! mesoderm formation GO:0001707 69 31 0,000 0,05706325 0,06972787 ! natural killer cell activation GO:0030101 45 31 0,000 0,05706325 0,06969248 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05706325 0,06965712 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05706325 0,06962179 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05706325 0,06958651 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05706325 0,06955125 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05706325 0,06951604 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05884971 0,07165607 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05884971 0,07161983 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05884971 0,07158362 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,05884971 0,07154745 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05884971 0,07151131 ! spliceosome assembly GO:0000245 67 32 0,000 0,05884971 0,07147521 ! spindle organization GO:0007051 46 32 0,000 0,05884971 0,07143915 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05884971 0,07140312 ! metanephros development GO:0001656 74 32 0,000 0,05884971 0,07136714 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05884971 0,07133118 ! response to ionizing radiation GO:0010212 65 32 0,000 0,05884971 0,07129526 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05884971 0,07125938 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05884971 0,07122354 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05884971 0,07118773 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05884971 0,07115196 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05884971 0,07111622 ! ovulation cycle GO:0042698 51 32 0,000 0,05884971 0,07108052 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05884971 0,07104486 ! BMP signaling pathway GO:0030509 64 32 0,000 0,05884971 0,07100923 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05884971 0,07097363 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,05884971 0,07093807 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06063284 0,07305088 ! post-embryonic development GO:0009791 69 33 0,000 0,06063284 0,07301432 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06063284 0,0729778 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06063284 0,07294131 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,06063284 0,07290486 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06063284 0,07286844 ! formation of primary germ layer GO:0001704 72 33 0,000 0,06063284 0,07283206 ! cell fate specification GO:0001708 52 33 0,000 0,06063284 0,07279572 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06063284 0,07275941 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06063284 0,07272314 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06063284 0,0726869 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06063284 0,0726507 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06063284 0,07261454 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,06241265 0,07470888 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,06241265 0,07467173 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,06241265 0,07463462 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,06241265 0,07459754 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,06241265 0,0745605 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,06241265 0,0745235 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,06241265 0,07448653 ! mismatch repair GO:0006298 46 34 0,000 0,06241265 0,0744496 ! spermatid development GO:0007286 63 34 0,000 0,06241265 0,07441271 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,06241265 0,07437585 ! placenta development GO:0001890 53 34 0,000 0,06241265 0,07433903 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,06241265 0,07430225 ! regulation of muscle development GO:0048634 70 35 0,000 0,06418916 0,07637938 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,06418916 0,07634163 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,06418916 0,07630391 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,06418916 0,07626623 ! odontogenesis GO:0042476 66 35 0,000 0,06418916 0,07622858 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,06418916 0,07619098 ! female gonad development GO:0008585 58 35 0,000 0,06418916 0,07615341 ! telencephalon development GO:0021537 68 35 0,000 0,06418916 0,07611587 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,06418916 0,07607838 ! cytokine production GO:0001816 59 35 0,000 0,06418916 0,07604092 ! neural tube formation GO:0001841 67 35 0,000 0,06418916 0,0760035 ! vesicle localization GO:0051648 64 35 0,000 0,06418916 0,07596611 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,06596235 0,07802626 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,06596235 0,07798792 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,06596235 0,07794961 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,06596235 0,07791135 ! cell junction organization GO:0034330 86 36 0,000 0,06596235 0,07787312 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,06596235 0,07783493 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,06596235 0,07779677 ! positive regulation of cell development GO:0010720 80 36 0,000 0,06596235 0,07775865 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,06596235 0,07772057 ! regulation of proteolysis GO:0030162 72 36 0,000 0,06596235 0,07768253 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,06596235 0,07764453 ! aerobic respiration GO:0009060 55 36 0,000 0,06596235 0,07760656 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,06596235 0,07756863 ! embryonic organ development GO:0048568 57 36 0,000 0,06596235 0,07753073 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,06596235 0,07749288 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,06596235 0,07745506 ! RNA export from nucleus GO:0006405 56 37 0,000 0,06773224 0,07949452 ! meiosis I GO:0007127 65 37 0,000 0,06773224 0,07945577 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,06773224 0,07941704 ! sister chromatid segregation GO:0000819 58 37 0,000 0,06773224 0,07937836 ! organic anion transport GO:0015711 68 37 0,000 0,06773224 0,07933972 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,06773224 0,07930111 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,06773224 0,07926254 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,06773224 0,079224 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,06773224 0,07918551 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,06773224 0,07914705 ! glycogen metabolic process GO:0005977 61 37 0,000 0,06773224 0,07910863 ! pigment metabolic process GO:0042440 80 37 0,000 0,06773224 0,07907025 ! spermatid differentiation GO:0048515 66 37 0,000 0,06773224 0,0790319 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,06949884 0,08105391 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,06949884 0,08101464 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,06949884 0,0809754 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,06949884 0,08093621 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,06949884 0,08089705 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,06949884 0,08085794 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,06949884 0,08081885 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,06949884 0,08077981 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,06949884 0,08074081 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,06949884 0,08070184 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,06949884 0,08066291 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,06949884 0,08062402 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,06949884 0,08058516 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,06949884 0,08054634 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,06949884 0,08050756 ! glucan metabolic process GO:0044042 62 38 0,000 0,06949884 0,08046882 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,07126215 0,08247077 ! learning GO:0007612 77 39 0,000 0,07126215 0,08243112 ! ear morphogenesis GO:0042471 60 39 0,000 0,07126215 0,08239151 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,07126215 0,08235194 ! segmentation GO:0035282 67 39 0,000 0,07126215 0,0823124 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07126215 0,0822729 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,07126215 0,08223344 ! RNA modification GO:0009451 57 39 0,000 0,07126215 0,08219402 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,07126215 0,08215464 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,07302218 0,08414337 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,07302218 0,08410309 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,07302218 0,08406285 ! feeding behavior GO:0007631 59 40 0,000 0,07302218 0,08402265 ! negative regulation of binding GO:0051100 72 40 0,000 0,07302218 0,08398248 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,07302218 0,08394236 ! mesenchymal cell development GO:0014031 87 40 0,000 0,07302218 0,08390227 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,07302218 0,08386222 ! maintenance of protein location GO:0045185 91 40 0,000 0,07302218 0,08382221 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,07477892 0,08579785 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,07477892 0,08575695 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,07477892 0,0857161 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,07477892 0,08567528 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,07477892 0,0856345 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,07477892 0,08559376 ! female gamete generation GO:0007292 61 41 0,000 0,07477892 0,08555306 ! polyol metabolic process GO:0019751 66 41 0,000 0,07477892 0,0855124 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,07477892 0,08547178 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,0765324 0,08743445 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,0765324 0,08739296 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,0765324 0,0873515 ! regulation of tube size GO:0035150 71 42 0,000 0,0765324 0,08731008 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,0765324 0,0872687 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,0765324 0,08722736 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,0765324 0,08718606 ! neuron migration GO:0001764 79 42 0,000 0,0765324 0,0871448 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,0765324 0,08710358 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,07828261 0,08905341 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,07828261 0,08901133 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,07828261 0,08896928 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,07828261 0,08892728 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,07828261 0,08888531 ! glucose transport GO:0015758 65 43 0,000 0,07828261 0,08884338 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,07828261 0,0888015 ! neural tube development GO:0021915 77 43 0,000 0,07828261 0,08875965 ! striated muscle contraction GO:0006941 77 43 0,000 0,07828261 0,08871784 ! phagocytosis GO:0006909 90 43 0,000 0,07828261 0,08867607 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,07828261 0,08863434 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,08002957 0,09056968 ! hexose transport GO:0008645 67 44 0,000 0,08002957 0,0905271 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,08002957 0,09048456 ! male sex differentiation GO:0046661 76 44 0,000 0,08002957 0,09044206 ! double-strand break repair GO:0006302 81 44 0,000 0,08002957 0,0903996 ! biopolymer methylation GO:0043414 84 44 0,000 0,08002957 0,09035718 ! B cell differentiation GO:0030183 107 44 0,000 0,08002957 0,09031479 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,08002957 0,09027245 ! maintenance of location in cell GO:0051651 97 44 0,000 0,08002957 0,09023015 ! glycolysis GO:0006096 65 45 0,000 0,08177327 0,09215292 ! leukocyte migration GO:0050900 68 45 0,000 0,08177327 0,09210978 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,08177327 0,09206668 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,08177327 0,09202361 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08177327 0,09198059 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08177327 0,09193761 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08177327 0,09189467 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08177327 0,09185177 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08177327 0,09180891 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,08351372 0,09371922 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,08351372 0,09367553 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,08351372 0,09363188 ! pigmentation GO:0043473 100 46 0,000 0,08351372 0,09358827 ! positive regulation of defense response GO:0031349 76 47 0,000 0,08525094 0,09549057 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,08525094 0,09544614 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,08525094 0,09540174 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,08525094 0,09535739 ! JNK cascade GO:0007254 91 47 0,000 0,08525094 0,09531308 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,08525094 0,09526881 ! methylation GO:0032259 90 47 0,000 0,08525094 0,09522458 ! mitochondrial transport GO:0006839 82 48 0,000 0,08698491 0,09711633 ! Notch signaling pathway GO:0007219 96 48 0,000 0,08698491 0,09707129 ! cellular component disassembly GO:0022411 86 48 0,000 0,08698491 0,09702629 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,08698491 0,09698133 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,08698491 0,09693641 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,08698491 0,09689153 ! activation of caspase activity GO:0006919 84 48 0,000 0,08698491 0,09684669 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,08698491 0,0968019 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,08698491 0,09675714 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,08698491 0,09671243 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,08871566 0,09859117 ! regulation of action potential GO:0001508 95 49 0,000 0,08871566 0,09854565 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,08871566 0,09850018 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,08871566 0,09845474 ! regulation of ion transport GO:0043269 77 49 0,000 0,08871566 0,09840935 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,08871566 0,098364 ! peptide metabolic process GO:0006518 76 49 0,000 0,08871566 0,09831869 ! response to temperature stimulus GO:0009266 76 49 0,000 0,08871566 0,09827343 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,08871566 0,0982282 ! endocrine system development GO:0035270 104 49 0,000 0,08871566 0,09818302 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,08871566 0,09813788 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,08871566 0,09809278 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,08871566 0,09804772 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,08871566 0,0980027 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,09044319 0,09986522 ! neuromuscular process GO:0050905 99 50 0,000 0,09044319 0,09981941 ! regulation of ossification GO:0030278 117 50 0,000 0,09044319 0,09977364 ! inner ear development GO:0048839 79 50 0,000 0,09044319 0,09972791 ! histone modification GO:0016570 91 50 0,000 0,09044319 0,09968223 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,09044319 0,09963659 ! positive regulation of binding GO:0051099 78 51 0,000 0,09216749 0,1014897 ! viral infectious cycle GO:0019058 99 51 0,000 0,09216749 0,10144327 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,09216749 0,10139688 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,09216749 0,10135054 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,09216749 0,10130424 ! excretion GO:0007588 83 51 0,000 0,09216749 0,10125798 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,09216749 0,10121177 ! chromatin remodeling GO:0006338 109 51 0,000 0,09216749 0,1011656 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,09216749 0,10111946 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,09216749 0,10107338 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,09216749 0,10102733 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,09216749 0,10098132 ! positive regulation of growth GO:0045927 90 52 0,000 0,09388859 0,10282018 ! amino acid activation GO:0043038 92 52 0,000 0,09388859 0,1027734 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,09388859 0,10272667 ! synapse organization GO:0050808 85 52 0,000 0,09388859 0,10267997 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,09560648 0,10451122 ! RNA catabolic process GO:0006401 93 53 0,000 0,09560648 0,10446375 ! regulation of translational initiation GO:0006446 82 53 0,000 0,09560648 0,10441633 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,09560648 0,10436896 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,09560648 0,10432163 ! cell maturation GO:0048469 100 53 0,000 0,09560648 0,10427434 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,09732117 0,10609639 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,09732117 0,10604834 ! cell recognition GO:0008037 85 54 0,000 0,09732117 0,10600033 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,09732117 0,10595237 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,09732117 0,10590444 ! chloride transport GO:0006821 90 55 0,000 0,09903266 0,10771817 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,09903266 0,10766949 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,09903266 0,10762086 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,09903266 0,10757227 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,09903266 0,10752373 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,09903266 0,10747523 ! aging GO:0007568 103 55 0,000 0,09903266 0,10742677 ! gastrulation GO:0007369 112 55 0,000 0,09903266 0,10737836 ! heart morphogenesis GO:0003007 97 55 0,000 0,09903266 0,10732999 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,09903266 0,10728167 ! RNA elongation GO:0006354 79 55 0,000 0,09903266 0,10723339 ! nuclear export GO:0051168 97 55 0,000 0,09903266 0,10718515 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,09903266 0,10713695 ! sensory perception of smell GO:0007608 80 56 0,000 0,10074097 0,10893608 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,10074097 0,10888714 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,10074097 0,10883825 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,10074097 0,1087894 ! regulation of DNA replication GO:0006275 101 56 0,000 0,10074097 0,10874059 ! proton transport GO:0015992 94 56 0,000 0,10074097 0,10869183 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,1024461 0,11048198 ! muscle fiber development GO:0048747 112 57 0,000 0,1024461 0,11043248 ! maintenance of location GO:0051235 118 57 0,000 0,1024461 0,11038303 ! hydrogen transport GO:0006818 97 58 0,000 0,10414804 0,1121666 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,10414804 0,11211642 ! adult behavior GO:0030534 99 58 0,000 0,10414804 0,11206628 ! positive regulation of secretion GO:0051047 95 59 0,000 0,10584682 0,1138433 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,10584682 0,11379243 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,10584682 0,1137416 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,10584682 0,11369083 ! DNA catabolic process GO:0006308 86 59 0,000 0,10584682 0,11364009 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,10584682 0,11358941 ! establishment of organelle localization GO:0051656 109 59 0,000 0,10584682 0,11353877 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,10754243 0,11530619 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,10754243 0,11525483 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,10754243 0,11520352 ! regulation of heart contraction GO:0008016 110 60 0,000 0,10754243 0,11515225 ! camera-type eye development GO:0043010 116 60 0,000 0,10754243 0,11510102 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,10923489 0,11686044 ! mesoderm development GO:0007498 119 61 0,000 0,10923489 0,11680851 ! tRNA processing GO:0008033 89 61 0,000 0,10923489 0,11675662 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,10923489 0,11670477 ! ear development GO:0043583 103 62 0,000 0,11092419 0,11845699 ! viral reproductive process GO:0022415 126 62 0,000 0,11092419 0,11840444 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,11092419 0,11835193 ! gonad development GO:0008406 98 62 0,000 0,11092419 0,11829947 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,11092419 0,11824705 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,11261034 0,11999136 ! detection of external stimulus GO:0009581 91 63 0,000 0,11261034 0,11993824 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,11261034 0,11988517 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,11261034 0,11983215 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,11429335 0,12156932 ! cell redox homeostasis GO:0045454 102 64 0,000 0,11429335 0,1215156 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,11429335 0,12146193 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,11429335 0,1214083 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,11429335 0,12135472 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,11597323 0,12308407 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,11597323 0,1230298 ! germ cell development GO:0007281 118 65 0,000 0,11597323 0,12297558 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,11597323 0,1229214 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,11764997 0,12464369 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,11764997 0,12458883 ! extracellular matrix organization GO:0030198 133 66 0,000 0,11764997 0,12453402 ! secondary metabolic process GO:0019748 116 66 0,000 0,11764997 0,12447926 ! developmental maturation GO:0021700 116 66 0,000 0,11764997 0,12442454 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,11932359 0,12613909 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,11932359 0,12608369 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,11932359 0,12602834 ! lung development GO:0030324 144 67 0,000 0,11932359 0,12597304 ! chromosome segregation GO:0007059 113 67 0,000 0,11932359 0,12591779 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,11932359 0,12586259 ! hexose catabolic process GO:0019320 104 67 0,000 0,11932359 0,12580743 ! adaptive immune response GO:0002250 119 67 0,000 0,11932359 0,12575233 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,11932359 0,12569727 ! amino acid transport GO:0006865 125 68 0,000 0,12099409 0,12740122 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,12099409 0,12734549 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,12099409 0,12728981 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,12099409 0,12723417 ! viral reproduction GO:0016032 134 68 0,000 0,12099409 0,12717859 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,12099409 0,12712305 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,12099409 0,12706756 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,12266148 0,12876244 ! negative regulation of cell size GO:0045792 134 69 0,000 0,12266148 0,12870629 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,12266148 0,12865018 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,12266148 0,12859413 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,12266148 0,12853812 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,12266148 0,12848216 ! antigen processing and presentation GO:0019882 104 69 0,000 0,12266148 0,12842625 ! respiratory tube development GO:0030323 150 70 0,000 0,12432576 0,13011213 ! amine catabolic process GO:0009310 117 71 0,000 0,12598694 0,13179329 ! reproductive structure development GO:0048608 113 71 0,000 0,12598694 0,13173602 ! humoral immune response GO:0006959 109 71 0,000 0,12598694 0,13167879 ! B cell activation GO:0042113 160 71 0,000 0,12598694 0,13162161 ! acute inflammatory response GO:0002526 113 72 0,000 0,12764502 0,13329597 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,12764502 0,13323814 ! carbohydrate transport GO:0008643 110 72 0,000 0,12764502 0,13318037 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,12764502 0,13312264 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,12764502 0,13306496 ! respiratory system development GO:0060541 153 72 0,000 0,12764502 0,13300733 ! learning or memory GO:0007611 147 73 0,000 0,12930001 0,13467352 ! regulation of blood pressure GO:0008217 125 73 0,000 0,12930001 0,13461525 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,12930001 0,13455702 ! axon guidance GO:0007411 139 73 0,000 0,12930001 0,13449885 ! fertilization GO:0009566 90 73 0,000 0,12930001 0,13444072 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,13095192 0,13609949 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,13095192 0,13604073 ! neurotransmitter transport GO:0006836 123 74 0,000 0,13095192 0,13598201 ! meiosis GO:0007126 121 74 0,000 0,13095192 0,13592335 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,13095192 0,13586474 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,13095192 0,13580617 ! organelle localization GO:0051640 136 74 0,000 0,13095192 0,13574766 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,13260075 0,13739767 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,13260075 0,13733853 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,13260075 0,13727943 ! meiotic cell cycle GO:0051321 122 75 0,000 0,13260075 0,13722039 ! rhythmic process GO:0048511 128 75 0,000 0,13260075 0,13716139 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1342465 0,13880408 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1342465 0,13874445 ! defense response to bacterium GO:0042742 89 76 0,000 0,1342465 0,13868488 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,1342465 0,13862536 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1342465 0,13856589 ! regulation of catabolic process GO:0009894 161 76 0,000 0,1342465 0,13850647 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,13588919 0,14014119 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,13588919 0,14008114 ! blood coagulation GO:0007596 146 78 0,000 0,13752881 0,14171063 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,13752881 0,14164997 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,13752881 0,14158936 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,13752881 0,1415288 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,13916538 0,14315174 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,13916538 0,14309056 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,13916538 0,14302944 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,13916538 0,14296836 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,1407989 0,14458478 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,1407989 0,1445231 ! protein import into nucleus GO:0006606 158 80 0,000 0,1407989 0,14446147 ! inorganic anion transport GO:0015698 138 80 0,000 0,1407989 0,14439989 ! digestion GO:0007586 112 81 0,000 0,14242937 0,14600983 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,14242937 0,14594764 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,14242937 0,14588551 ! nuclear import GO:0051170 161 81 0,000 0,14242937 0,14582343 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,14242937 0,14576141 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,1440568 0,14736423 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,1440568 0,1473016 ! response to drug GO:0042493 143 82 0,000 0,1440568 0,14723902 ! response to nutrient GO:0007584 125 82 0,000 0,1440568 0,1471765 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,1440568 0,14711403 ! regulation of lyase activity GO:0051339 160 83 0,000 0,1456812 0,14870978 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,14730257 0,15030109 ! hemostasis GO:0007599 158 84 0,000 0,14730257 0,15023738 ! negative regulation of growth GO:0045926 155 84 0,000 0,14730257 0,15017372 ! regulation of ligase activity GO:0051340 142 84 0,000 0,14730257 0,15011011 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,14730257 0,15004656 ! response to unfolded protein GO:0006986 131 85 0,000 0,14892091 0,15163086 ! nucleosome assembly GO:0006334 122 85 0,000 0,14892091 0,15156671 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,14892091 0,15150263 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,15053624 0,15308123 ! chromatin assembly GO:0031497 124 86 0,000 0,15053624 0,15301656 ! mitochondrion organization GO:0007005 148 86 0,000 0,15053624 0,15295194 ! alcohol catabolic process GO:0046164 130 86 0,000 0,15053624 0,15288737 ! amine transport GO:0015837 155 86 0,000 0,15053624 0,15282286 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,15214855 0,15439453 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,15214855 0,15432943 ! protein localization in nucleus GO:0034504 176 87 0,000 0,15214855 0,1542644 ! cellular respiration GO:0045333 135 88 0,000 0,15375786 0,15583042 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,15375786 0,15576481 ! regulation of DNA binding GO:0051101 155 88 0,000 0,15375786 0,15569925 ! regulation of neurological system process GO:0031644 148 88 0,000 0,15375786 0,15563375 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,15375786 0,1555683 ! cellular defense response GO:0006968 114 89 0,000 0,15536417 0,15712744 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,15696748 0,15868225 ! sex differentiation GO:0007548 145 90 0,000 0,15696748 0,15861561 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,15696748 0,15854902 ! sterol metabolic process GO:0016125 152 91 0,000 0,1585678 0,16009825 ! response to protein stimulus GO:0051789 149 91 0,000 0,1585678 0,1600311 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,1585678 0,159964 ! regulation of defense response GO:0031347 149 92 0,000 0,16016514 0,16150768 ! nucleosome organization GO:0034728 138 92 0,000 0,16016514 0,16144002 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,16016514 0,16137241 ! vitamin metabolic process GO:0006766 139 92 0,000 0,16016514 0,16130487 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,1617595 0,16284241 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,1617595 0,1627743 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,1617595 0,16270625 ! female pregnancy GO:0007565 164 94 0,000 0,16335088 0,16423829 ! transcription initiation GO:0006352 153 94 0,000 0,16335088 0,16416968 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,16652475 0,16728958 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,16652475 0,16721976 ! positive regulation of immune response GO:0050778 156 96 0,000 0,16652475 0,16715 ! detection of stimulus GO:0051606 151 96 0,000 0,16652475 0,16708029 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,16810724 0,16859776 ! protein ubiquitination GO:0016567 217 97 0,000 0,16810724 0,16852751 ! hormone metabolic process GO:0042445 157 97 0,000 0,16810724 0,16845732 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,16968679 0,16996936 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,16968679 0,16989863 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,17126338 0,17140587 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,17126338 0,1713346 ! cell cycle arrest GO:0007050 213 100 0,000 0,17283704 0,17283704