pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/763-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 4,811E-06 0,01157637 ! actin filament-based movement GO:0030048 43 20 2,000 4,811E-06 5,788E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 6,484E-06 5,201E-03 ! vasculogenesis GO:0001570 46 25 2,000 9,651E-06 5,805E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,693E-05 0,0129568 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,693E-05 0,01079733 ! interaction with symbiont GO:0051702 13 6 1,000 4,035E-05 0,01386754 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 4,035E-05 0,01213409 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 4,722E-05 0,01262386 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 5,642E-05 0,01357575 ! vesicle fusion GO:0006906 17 7 1,000 5,642E-05 0,01234159 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 5,642E-05 0,01131313 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 5,642E-05 0,01044289 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 7,515E-05 0,01291556 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,515E-05 0,01205452 ! regulation of protein polymerization GO:0032271 103 53 2,000 9,513E-05 0,01430502 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 9,652E-05 0,01366077 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 9,652E-05 0,01290184 ! protein heterooligomerization GO:0051291 16 9 1,000 9,652E-05 0,0122228 ! gas homeostasis GO:0033483 16 9 1,000 9,652E-05 0,01161166 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,205E-04 0,01380872 ! localization within membrane GO:0051668 20 10 1,000 1,205E-04 0,01318105 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 1,378E-04 0,01441823 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,448E-04 0,0145152 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,472E-04 0,0141619 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,472E-04 0,01361722 GO:0010812|negative regulation of cell-substrate adhesion, ! gland morphogenesis GO:0022612 29 12 1,000 1,764E-04 0,01571875 ! lipid localization GO:0010876 28 13 1,000 2,082E-04 0,01789423 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 2,082E-04 0,01727719 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,082E-04 0,01670128 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 2,082E-04 0,01616253 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 2,273E-04 0,01708783 ! regulation of RNA stability GO:0043487 32 14 1,000 2,427E-04 0,01769468 ! regulation of vasodilation GO:0042312 26 15 1,000 2,797E-04 0,01979541 ! cell killing GO:0001906 29 15 1,000 2,797E-04 0,01922983 ! protein oligomerization GO:0051259 139 78 2,000 3E-04 0,02005305 ! regulation of peptidase activity GO:0052547 134 79 2,000 3,115E-04 0,0202576 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 3,194E-04 0,02022045 ! complement activation, alternative pathway GO:0006957 18 16 1,000 3,194E-04 0,01970198 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 3,194E-04 0,01920943 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 3,616E-04 0,02121716 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 3,616E-04 0,02071198 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 4,063E-04 0,02273496 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,063E-04 0,02221825 ! negative regulation of defense response GO:0031348 25 19 1,000 4,536E-04 0,02425458 ! lipid phosphorylation GO:0046834 35 19 1,000 4,536E-04 0,02372731 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 5,035E-04 0,02577538 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 5,352E-04 0,02682674 ! inactivation of MAPK activity GO:0000188 39 21 1,000 5,559E-04 0,0272968 ! cytolysis GO:0019835 24 21 1,000 5,559E-04 0,02675086 ! regulation of vasoconstriction GO:0019229 39 21 1,000 5,559E-04 0,02622634 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 6,109E-04 0,02826418 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 6,109E-04 0,02773089 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 6,109E-04 0,02721736 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 6,683E-04 0,02923646 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,683E-04 0,02871438 GO:0010810|regulation of cell-substrate adhesion, ! vesicle docking GO:0048278 47 24 1,000 7,283E-04 0,0307426 ! membrane depolarization GO:0051899 39 24 1,000 7,283E-04 0,03021255 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 7,283E-04 0,02970048 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 7,908E-04 0,03171142 ! interaction with host GO:0051701 62 25 1,000 7,908E-04 0,03119156 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 7,908E-04 0,03068847 ! regulation of blood coagulation GO:0030193 40 25 1,000 7,908E-04 0,03020136 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 8,558E-04 0,03217278 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 8,558E-04 0,03167781 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 8,558E-04 0,03119784 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 9,233E-04 0,0331556 ! complement activation, classical pathway GO:0006958 48 29 1,000 1,066E-03 0,0377069 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,066E-03 0,03716043 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 1,066E-03 0,03662956 ! regulation of coagulation GO:0050818 46 29 1,000 1,066E-03 0,03611365 ! membrane docking GO:0022406 61 30 1,000 1,141E-03 0,03811537 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,141E-03 0,03759324 ! cholesterol homeostasis GO:0042632 53 31 1,000 1,218E-03 0,03960083 GO:0055092|sterol homeostasis, ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 1,218E-03 0,03907282 ! triglyceride metabolic process GO:0006641 43 31 1,000 1,218E-03 0,0385587 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 1,298E-03 0,04055214 ! cholesterol transport GO:0030301 56 32 1,000 1,298E-03 0,04003224 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 1,298E-03 0,0395255 ! sterol transport GO:0015918 57 33 1,000 1,38E-03 0,04150558 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 1,465E-03 0,04350912 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 1,552E-03 0,04553501 ! neutral lipid metabolic process GO:0006638 50 35 1,000 1,552E-03 0,04498639 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 1,552E-03 0,04445084 ! regulation of microtubule-based process GO:0032886 78 35 1,000 1,552E-03 0,04392789 ! tissue remodeling GO:0048771 76 37 1,000 1,733E-03 0,04849511 ! glycerol ether metabolic process GO:0006662 53 37 1,000 1,733E-03 0,0479377 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 1,733E-03 0,04739295 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 1,828E-03 0,04941145 GO:0006956|complement activation, ! lipid homeostasis GO:0055088 67 38 1,000 1,828E-03 0,04886243 ! mammary gland development GO:0030879 86 39 1,000 1,925E-03 0,05088375 ! organic ether metabolic process GO:0018904 55 39 1,000 1,925E-03 0,05033067 ! cytokinesis GO:0000910 72 40 1,000 2,024E-03 0,05235451 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 2,335E-03 0,05977548 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 2,335E-03 0,05914627 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 2,555E-03 0,06403359 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 2,555E-03 0,06337345 ! cell growth GO:0016049 84 45 1,000 2,555E-03 0,06272679 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 2,668E-03 0,06484694 ! response to insulin stimulus GO:0032868 95 46 1,000 2,668E-03 0,06419847 ! regulation of JNK cascade GO:0046328 94 47 1,000 2,784E-03 0,06631766 ! protein homooligomerization GO:0051260 76 47 1,000 2,784E-03 0,06566748 ! positive regulation of cell cycle GO:0045787 89 48 1,000 2,902E-03 0,06778557 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 2,902E-03 0,06713379 ! activation of caspase activity GO:0006919 84 48 1,000 2,902E-03 0,06649442 ! regulation of inflammatory response GO:0050727 75 48 1,000 2,902E-03 0,06586711 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 3,022E-03 0,06795627 GO:0019724|B cell mediated immunity, ! excretion GO:0007588 83 51 1,000 3,27E-03 0,07284064 ! vesicle organization GO:0016050 107 51 1,000 3,27E-03 0,07217238 ! regulation of cell shape GO:0008360 125 51 1,000 3,27E-03 0,07151626 ! regulation of muscle contraction GO:0006937 81 52 1,000 3,397E-03 0,07362895 ! membrane fusion GO:0006944 110 52 1,000 3,397E-03 0,07297155 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 3,526E-03 0,07508266 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 3,526E-03 0,07442404 ! response to UV GO:0009411 104 53 1,000 3,526E-03 0,07377687 ! activation of phospholipase C activity GO:0007202 103 54 1,000 3,658E-03 0,07587372 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 3,792E-03 0,07798143 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 3,792E-03 0,07732057 ! regulation of actin filament length GO:0030832 105 56 1,000 3,928E-03 0,07942648 ! positive regulation of organelle organization GO:0010638 100 56 1,000 3,928E-03 0,07876459 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 4,067E-03 0,08086863 ! positive regulation of cell migration GO:0030335 126 57 1,000 4,067E-03 0,08020577 ! lipid modification GO:0030258 97 57 1,000 4,067E-03 0,07955369 ! regulation of phospholipase activity GO:0010517 106 57 1,000 4,067E-03 0,07891213 ! positive regulation of lipase activity GO:0060193 108 58 1,000 4,208E-03 0,08099094 ! regulation of cellular component size GO:0032535 109 59 1,000 4,351E-03 0,08307956 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 4,496E-03 0,0851776 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 4,496E-03 0,08451215 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 4,644E-03 0,08660809 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 4,945E-03 0,09152474 ! cell redox homeostasis GO:0045454 102 64 1,000 5,099E-03 0,093657 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 5,099E-03 0,09294747 ! positive regulation of cell motion GO:0051272 146 64 1,000 5,099E-03 0,09224862 ! regulation of cellular response to stress GO:0080135 128 67 1,000 5,575E-03 0,1000989 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 5,575E-03 0,09935743 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 5,575E-03 0,09862686 ! adaptive immune response GO:0002250 119 67 1,000 5,575E-03 0,09790696 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 5,575E-03 0,09719749 ! negative regulation of kinase activity GO:0033673 131 68 1,000 5,738E-03 0,09931752 ! regulation of lipase activity GO:0060191 130 68 1,000 5,738E-03 0,09860811 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 5,738E-03 0,09790876 ! humoral immune response GO:0006959 109 71 1,000 6,239E-03 0,10571825 ! acute inflammatory response GO:0002526 113 72 1,000 6,411E-03 0,10786449 ! regulation of caspase activity GO:0043281 122 72 1,000 6,411E-03 0,10711543 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 6,411E-03 0,10637671 ! negative regulation of transferase activity GO:0051348 140 72 1,000 6,411E-03 0,1056481 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 6,76E-03 0,11064827 ! leukocyte mediated immunity GO:0002443 128 74 1,000 6,76E-03 0,10990065 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 6,76E-03 0,10916306 ! cell-matrix adhesion GO:0007160 163 75 1,000 6,938E-03 0,11128869 ! regulation of actin filament-based process GO:0032970 152 77 1,000 7,3E-03 0,11632168 ! blood coagulation GO:0007596 146 78 1,000 7,485E-03 0,11847238 GO:0050817|coagulation, ! positive regulation of phosphorylation GO:0042327 129 79 1,000 7,671E-03 0,1206279 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 8,05E-03 0,12576396 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 8,05E-03 0,12495258 ! cell-substrate adhesion GO:0031589 171 81 1,000 8,05E-03 0,1241516 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 8,242E-03 0,12631165 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 8,274E-03 0,12599507 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 8,274E-03 0,12520265 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,274E-03 0,12442013 ! positive regulation of helicase activity GO:0051096 11 5 0,000 8,274E-03 0,12364734 ! neuron fate determination GO:0048664 7 5 0,000 8,274E-03 0,12288408 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,274E-03 0,12213019 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 8,274E-03 0,1213855 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 8,274E-03 0,12064983 ! polyol transport GO:0015791 12 5 0,000 8,274E-03 0,11992302 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 8,274E-03 0,11920492 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,274E-03 0,11849537 ! response to superoxide GO:0000303 10 5 0,000 8,274E-03 0,11779421 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,274E-03 0,1171013 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 8,274E-03 0,1164165 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 8,274E-03 0,11573966 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,274E-03 0,11507064 ! female meiosis GO:0007143 7 5 0,000 8,274E-03 0,11440932 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,274E-03 0,11375555 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,274E-03 0,11310921 ! cobalt ion transport GO:0006824 11 5 0,000 8,274E-03 0,11247018 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 8,274E-03 0,11183832 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 8,274E-03 0,11121353 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 8,274E-03 0,11059567 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,274E-03 0,10998465 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,274E-03 0,10938034 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 8,274E-03 0,10878263 ! embryonic camera-type eye development GO:0031076 10 5 0,000 8,274E-03 0,10819142 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,274E-03 0,1076066 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 8,274E-03 0,10702807 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 8,274E-03 0,10645573 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,274E-03 0,10588948 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,274E-03 0,10532921 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,274E-03 0,10477485 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 8,274E-03 0,10422629 ! negative chemotaxis GO:0050919 14 5 0,000 8,274E-03 0,10368344 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,274E-03 0,10314622 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,274E-03 0,10261454 ! sensory perception of bitter taste GO:0050913 7 5 0,000 8,274E-03 0,10208831 ! behavioral response to pain GO:0048266 9 5 0,000 8,274E-03 0,10156746 ! clathrin coat assembly GO:0048268 14 5 0,000 8,274E-03 0,10105189 ! Notch receptor processing GO:0007220 8 5 0,000 8,274E-03 0,10054152 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,274E-03 0,10003629 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,274E-03 0,09953611 ! micturition GO:0060073 9 5 0,000 8,274E-03 0,0990409 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,274E-03 0,0985506 ! copulation GO:0007620 9 5 0,000 8,274E-03 0,09806513 ! glial cell fate commitment GO:0021781 13 5 0,000 8,274E-03 0,09758442 ! protein maturation by protein folding GO:0022417 13 5 0,000 8,274E-03 0,0971084 ! spermidine metabolic process GO:0008216 7 5 0,000 8,274E-03 0,096637 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,274E-03 0,09617015 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,274E-03 0,09570779 ! apoptotic cell clearance GO:0043277 20 5 0,000 8,274E-03 0,09524986 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,274E-03 0,09479629 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,274E-03 0,09434702 ! grooming behavior GO:0007625 6 5 0,000 8,274E-03 0,09390199 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,274E-03 0,09346113 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 8,274E-03 0,0930244 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,274E-03 0,09259173 ! response to protozoan GO:0001562 10 5 0,000 8,274E-03 0,09216306 ! positive regulation of glycolysis GO:0045821 14 5 0,000 8,274E-03 0,09173835 ! lymph vessel development GO:0001945 10 5 0,000 8,274E-03 0,09131753 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 8,274E-03 0,09090055 ! endochondral ossification GO:0001958 16 5 0,000 8,274E-03 0,09048737 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,274E-03 0,09007792 ! parathyroid gland development GO:0060017 13 5 0,000 8,274E-03 0,08967217 ! anagen GO:0042640 6 5 0,000 8,274E-03 0,08927005 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,274E-03 0,08887152 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,274E-03 0,08847654 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 8,274E-03 0,08808505 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 8,274E-03 0,08769701 ! dorsal spinal cord development GO:0021516 7 5 0,000 8,274E-03 0,08731237 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 8,274E-03 0,0869311 ! sphingoid catabolic process GO:0046521 6 5 0,000 8,274E-03 0,08655314 ! skeletal myofibril assembly GO:0014866 10 5 0,000 8,274E-03 0,08617845 ! smooth muscle tissue development GO:0048745 28 5 0,000 8,274E-03 0,08580699 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,274E-03 0,08543872 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,274E-03 0,0850736 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,274E-03 0,08471158 ! cardiac muscle fiber development GO:0048739 10 5 0,000 8,274E-03 0,08435263 ! transepithelial chloride transport GO:0030321 9 5 0,000 8,274E-03 0,08399671 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,274E-03 0,08364379 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 8,274E-03 0,08329381 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 8,274E-03 0,08294676 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,274E-03 0,08260258 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,274E-03 0,08226125 ! histidine catabolic process GO:0006548 6 5 0,000 8,274E-03 0,08192272 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 8,274E-03 0,08158697 ! microvillus organization GO:0032528 7 5 0,000 8,274E-03 0,08125396 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 8,274E-03 0,08092366 ! L-serine biosynthetic process GO:0006564 6 5 0,000 8,274E-03 0,08059604 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,274E-03 0,08027105 ! tryptophan metabolic process GO:0006568 9 5 0,000 8,274E-03 0,07994868 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 8,274E-03 0,07962889 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,274E-03 0,07931164 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 8,274E-03 0,07899691 ! polyol catabolic process GO:0046174 7 5 0,000 8,274E-03 0,07868467 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,274E-03 0,07837489 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,274E-03 0,07806753 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,274E-03 0,07776258 ! muscle cell migration GO:0014812 8 5 0,000 8,274E-03 0,07746001 ! mitochondrial fission GO:0000266 8 5 0,000 8,274E-03 0,07715977 ! sister chromatid cohesion GO:0007062 12 5 0,000 8,274E-03 0,07686186 ! mRNA transcription GO:0009299 9 5 0,000 8,274E-03 0,07656624 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 8,274E-03 0,07627288 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 8,274E-03 0,07598176 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 8,274E-03 0,07569286 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,274E-03 0,07540614 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,274E-03 0,07512159 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,274E-03 0,07483918 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,274E-03 0,07455888 ! response to food GO:0032094 6 5 0,000 8,274E-03 0,07428068 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,274E-03 0,07400454 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,274E-03 0,07373045 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 8,274E-03 0,07345838 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,274E-03 0,07318831 ! paraxial mesoderm development GO:0048339 14 5 0,000 8,274E-03 0,07292022 ! forebrain neuron development GO:0021884 13 5 0,000 8,274E-03 0,07265409 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,274E-03 0,0723899 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 8,274E-03 0,07212761 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,274E-03 0,07186723 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,274E-03 0,07160871 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,274E-03 0,07135205 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 8,274E-03 0,07109722 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,274E-03 0,0708442 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 8,274E-03 0,07059298 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 8,274E-03 0,07034354 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 8,274E-03 0,07009585 ! basic amino acid transport GO:0015802 11 5 0,000 8,274E-03 0,0698499 ! cellular glucose homeostasis GO:0001678 5 5 0,000 8,274E-03 0,06960567 ! early endosome to late endosome transport GO:0045022 12 5 0,000 8,274E-03 0,06936314 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,274E-03 0,0691223 ! depyrimidination GO:0045008 10 5 0,000 8,274E-03 0,06888312 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,274E-03 0,06864559 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,274E-03 0,0684097 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,274E-03 0,06817542 ! zinc ion homeostasis GO:0055069 8 5 0,000 8,274E-03 0,06794274 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 8,274E-03 0,06771164 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 8,274E-03 0,06748211 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,274E-03 0,06725413 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,274E-03 0,06702768 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,274E-03 0,06680276 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 8,274E-03 0,06657934 ! peptidyl-arginine modification GO:0018195 9 5 0,000 8,274E-03 0,0663574 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,274E-03 0,06613695 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,274E-03 0,06591795 ! response to arsenic GO:0046685 10 5 0,000 8,274E-03 0,0657004 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 8,274E-03 0,06548428 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 8,274E-03 0,06526958 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 8,274E-03 0,06505628 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 8,274E-03 0,06484437 ! response to cadmium ion GO:0046686 7 5 0,000 8,274E-03 0,06463384 ! bile acid biosynthetic process GO:0006699 6 5 0,000 8,274E-03 0,06442466 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 8,274E-03 0,06421684 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,274E-03 0,06401036 ! decidualization GO:0046697 11 5 0,000 8,274E-03 0,0638052 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 8,274E-03 0,06360135 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 8,274E-03 0,06339879 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,274E-03 0,06319753 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,274E-03 0,06299754 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 8,274E-03 0,06279881 ! base conversion or substitution editing GO:0016553 5 5 0,000 8,274E-03 0,06260133 ! neural tube patterning GO:0021532 7 5 0,000 8,274E-03 0,06240508 ! embryonic cleavage GO:0040016 6 5 0,000 8,274E-03 0,06221007 ! peroxisome fission GO:0016559 5 5 0,000 8,274E-03 0,06201627 ! histone demethylation GO:0016577 10 5 0,000 8,274E-03 0,06182367 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 8,274E-03 0,06163226 ! mitotic recombination GO:0006312 9 5 0,000 8,274E-03 0,06144204 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,274E-03 0,06125299 ! metaphase plate congression GO:0051310 7 5 0,000 8,274E-03 0,0610651 ! regulation of sterol transport GO:0032371 7 5 0,000 8,274E-03 0,06087835 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,274E-03 0,06069275 ! enteric nervous system development GO:0048484 8 5 0,000 8,274E-03 0,06050827 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 8,274E-03 0,06032491 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 8,274E-03 0,06014266 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 8,274E-03 0,05996151 ! muscle cell proliferation GO:0033002 11 5 0,000 8,274E-03 0,05978145 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,274E-03 0,05960246 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 8,274E-03 0,05942454 ! plasminogen activation GO:0031639 5 5 0,000 8,274E-03 0,05924768 ! B cell homeostasis GO:0001782 13 5 0,000 8,274E-03 0,05907187 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 8,274E-03 0,0588971 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,274E-03 0,05872337 ! metaphase GO:0051323 8 5 0,000 8,274E-03 0,05855065 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 8,274E-03 0,05837895 ! cellular response to nutrient GO:0031670 8 5 0,000 8,274E-03 0,05820825 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,274E-03 0,05803855 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,274E-03 0,05786983 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,274E-03 0,05770209 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 8,274E-03 0,05753532 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 8,274E-03 0,05736951 ! response to redox state GO:0051775 5 5 0,000 8,274E-03 0,05720466 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 8,274E-03 0,05704075 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 8,274E-03 0,05687778 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,274E-03 0,05671573 ! regulation of telomerase activity GO:0051972 6 5 0,000 8,274E-03 0,05655461 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,274E-03 0,05639439 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 8,274E-03 0,05623509 ! porphyrin catabolic process GO:0006787 12 5 0,000 8,274E-03 0,05607668 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 8,274E-03 0,05591916 ! striatum development GO:0021756 9 5 0,000 8,274E-03 0,05576252 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 8,274E-03 0,05560676 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 8,274E-03 0,05545187 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,274E-03 0,05529784 ! glial cell migration GO:0008347 11 5 0,000 8,274E-03 0,05514466 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,274E-03 0,05499232 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 8,274E-03 0,05484083 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,274E-03 0,05469017 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,274E-03 0,05454033 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,274E-03 0,05439132 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,274E-03 0,05424311 ! neuroprotection GO:0043526 6 5 0,000 8,274E-03 0,05409571 ! neural plate development GO:0001840 8 5 0,000 8,274E-03 0,05394911 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,274E-03 0,0538033 ! regulation of sensory perception GO:0051931 7 5 0,000 8,274E-03 0,05365828 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,274E-03 0,05351404 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,274E-03 0,05337057 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 8,274E-03 0,05322786 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 8,274E-03 0,05308592 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,274E-03 0,05294474 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,274E-03 0,0528043 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,274E-03 0,05266461 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,274E-03 0,05252565 ! spindle assembly GO:0051225 6 5 0,000 8,274E-03 0,05238742 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 8,274E-03 0,05224992 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,274E-03 0,05211314 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,274E-03 0,05197708 ! drug metabolic process GO:0017144 6 5 0,000 8,274E-03 0,05184172 ! stem cell division GO:0017145 11 5 0,000 8,274E-03 0,05170707 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 8,274E-03 0,05157311 ! organ regeneration GO:0031100 7 5 0,000 8,274E-03 0,05143985 ! carnitine metabolic process GO:0009437 7 5 0,000 8,274E-03 0,05130727 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 8,274E-03 0,05117538 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,274E-03 0,05104416 ! response to oxygen levels GO:0070482 176 83 1,000 8,437E-03 0,05191606 ! hemostasis GO:0007599 158 84 1,000 8,634E-03 0,05299077 ! gland development GO:0048732 206 88 1,000 9,441E-03 0,05779741 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 9,648E-03 0,05891394 ! regulation of cell adhesion GO:0030155 212 89 1,000 9,648E-03 0,05876479 ! ossification GO:0001503 188 90 1,000 9,856E-03 0,05988549 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,921E-03 0,06012406 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,921E-03 0,05997299 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 9,921E-03 0,05982268 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,921E-03 0,05967313 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,921E-03 0,05952432 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 9,921E-03 0,05937625 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 9,921E-03 0,05922891 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,921E-03 0,0590823 ! sleep GO:0030431 13 6 0,000 9,921E-03 0,05893642 ! response to oxygen radical GO:0000305 11 6 0,000 9,921E-03 0,05879126 ! positive regulation of axon extension GO:0045773 11 6 0,000 9,921E-03 0,05864681 ! myoblast cell fate commitment GO:0048625 16 6 0,000 9,921E-03 0,05850307 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 9,921E-03 0,05836003 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 9,921E-03 0,05821769 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,921E-03 0,05807604 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,921E-03 0,05793508 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 9,921E-03 0,0577948 ! forebrain regionalization GO:0021871 8 6 0,000 9,921E-03 0,0576552 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,921E-03 0,05751627 ! male meiosis GO:0007140 7 6 0,000 9,921E-03 0,05737801 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,921E-03 0,05724041 ! response to zinc ion GO:0010043 9 6 0,000 9,921E-03 0,05710347 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,921E-03 0,05696719 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 9,921E-03 0,05683155 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 9,921E-03 0,05669656 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,921E-03 0,05656221 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,921E-03 0,05642849 ! malate metabolic process GO:0006108 11 6 0,000 9,921E-03 0,0562954 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 9,921E-03 0,05616294 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 9,921E-03 0,05603111 ! protein refolding GO:0042026 15 6 0,000 9,921E-03 0,05589989 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,921E-03 0,05576928 ! opsonization GO:0008228 8 6 0,000 9,921E-03 0,05563928 ! mating behavior GO:0007617 7 6 0,000 9,921E-03 0,05550989 ! neuron remodeling GO:0016322 15 6 0,000 9,921E-03 0,05538109 ! erythrocyte maturation GO:0043249 7 6 0,000 9,921E-03 0,0552529 ! embryonic hemopoiesis GO:0035162 14 6 0,000 9,921E-03 0,05512529 ! equilibrioception GO:0050957 14 6 0,000 9,921E-03 0,05499827 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,921E-03 0,05487184 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 9,921E-03 0,05474599 ! photoreceptor cell development GO:0042461 10 6 0,000 9,921E-03 0,05462071 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,921E-03 0,05449601 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,921E-03 0,05437187 ! response to interferon-gamma GO:0034341 15 6 0,000 9,921E-03 0,0542483 ! toxin metabolic process GO:0009404 11 6 0,000 9,921E-03 0,05412529 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,921E-03 0,05400283 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,921E-03 0,05388093 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 9,921E-03 0,05375957 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 9,921E-03 0,05363877 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 9,921E-03 0,0535185 ! cGMP-mediated signaling GO:0019934 13 6 0,000 9,921E-03 0,05339877 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,921E-03 0,05327958 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 9,921E-03 0,05316092 ! thymic T cell selection GO:0045061 12 6 0,000 9,921E-03 0,05304278 ! protein lipoylation GO:0009249 10 6 0,000 9,921E-03 0,05292517 ! cysteine metabolic process GO:0006534 10 6 0,000 9,921E-03 0,05280808 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,921E-03 0,0526915 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,921E-03 0,05257544 ! glutamate catabolic process GO:0006538 10 6 0,000 9,921E-03 0,05245989 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 9,921E-03 0,05234485 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 9,921E-03 0,05223031 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 9,921E-03 0,05211627 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 9,921E-03 0,05200273 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,921E-03 0,05188968 ! hyperosmotic response GO:0006972 9 6 0,000 9,921E-03 0,05177712 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 9,921E-03 0,05166505 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 9,921E-03 0,05155346 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,921E-03 0,05144235 ! urea metabolic process GO:0019627 7 6 0,000 9,921E-03 0,05133172 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,921E-03 0,05122157 ! neutrophil activation GO:0042119 8 6 0,000 9,921E-03 0,05111189 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,921E-03 0,05100267 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 9,921E-03 0,05089393 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,921E-03 0,05078564 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,921E-03 0,05067782 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,921E-03 0,05057045 ! neuron apoptosis GO:0051402 9 6 0,000 9,921E-03 0,05046353 ! nucleoside salvage GO:0043174 9 6 0,000 9,921E-03 0,05035707 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 9,921E-03 0,05025105 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,921E-03 0,05014549 ! T cell mediated immunity GO:0002456 16 6 0,000 9,921E-03 0,05004036 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,921E-03 0,04993567 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 9,921E-03 0,04983142 ! carnitine transport GO:0015879 10 6 0,000 9,921E-03 0,04972761 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 9,921E-03 0,04962422 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,921E-03 0,04952127 ! positive regulation of exocytosis GO:0045921 8 6 0,000 9,921E-03 0,04941874 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 9,921E-03 0,04931663 ! 5S class rRNA transcription GO:0042791 11 6 0,000 9,921E-03 0,04921495 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,921E-03 0,04911369 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 9,921E-03 0,04901284 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 9,921E-03 0,0489124 ! sodium ion homeostasis GO:0055078 11 6 0,000 9,921E-03 0,04881237 ! establishment of spindle localization GO:0051293 12 6 0,000 9,921E-03 0,04871276 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,921E-03 0,04861355 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,921E-03 0,04851474 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 9,921E-03 0,04841633 ! neural nucleus development GO:0048857 14 6 0,000 9,921E-03 0,04831832 ! response to UV-C GO:0010225 11 6 0,000 9,921E-03 0,04822071 ! astrocyte development GO:0014002 15 6 0,000 9,921E-03 0,04812349 ! protein targeting to lysosome GO:0006622 10 6 0,000 9,921E-03 0,04802666 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,921E-03 0,04793022 ! regulation of dendrite development GO:0050773 16 6 0,000 9,921E-03 0,04783417 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,921E-03 0,0477385 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 9,921E-03 0,04764322 ! response to copper ion GO:0046688 10 6 0,000 9,921E-03 0,04754831 ! response to exogenous dsRNA GO:0043330 10 6 0,000 9,921E-03 0,04745378 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 9,921E-03 0,04735963 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,921E-03 0,04726584 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,921E-03 0,04717243 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,921E-03 0,04707939 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 9,921E-03 0,04698671 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,921E-03 0,0468944 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,921E-03 0,04680245 ! hair follicle maturation GO:0048820 7 6 0,000 9,921E-03 0,04671086 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,921E-03 0,04661963 ! Schwann cell development GO:0014044 15 6 0,000 9,921E-03 0,04652875 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,921E-03 0,04643823 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,921E-03 0,04634806 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 9,921E-03 0,04625824 ! subpallium development GO:0021544 10 6 0,000 9,921E-03 0,04616876 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 9,921E-03 0,04607964 ! histone ubiquitination GO:0016574 8 6 0,000 9,921E-03 0,04599085 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 9,921E-03 0,04590241 ! maintenance of organ identity GO:0048496 9 6 0,000 9,921E-03 0,0458143 ! G2 phase GO:0051319 16 6 0,000 9,921E-03 0,04572653 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 9,921E-03 0,0456391 ! establishment of planar polarity GO:0001736 7 6 0,000 9,921E-03 0,04555201 ! regulation of mast cell activation GO:0033003 12 6 0,000 9,921E-03 0,04546524 ! membrane to membrane docking GO:0022614 14 6 0,000 9,921E-03 0,0453788 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,921E-03 0,0452927 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 9,921E-03 0,04520691 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,921E-03 0,04512146 ! receptor internalization GO:0031623 10 6 0,000 9,921E-03 0,04503632 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 9,921E-03 0,04495151 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 9,921E-03 0,04486701 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,921E-03 0,04478284 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 9,921E-03 0,04469897 ! protein deubiquitination GO:0016579 14 6 0,000 9,921E-03 0,04461542 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 9,921E-03 0,04453218 ! protein destabilization GO:0031648 9 6 0,000 9,921E-03 0,04444926 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,921E-03 0,04436664 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 9,921E-03 0,04428432 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,921E-03 0,04420232 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 9,921E-03 0,04412061 ! progesterone metabolic process GO:0042448 10 6 0,000 9,921E-03 0,04403921 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 9,921E-03 0,04395811 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 9,921E-03 0,0438773 ! negative regulation of axon extension GO:0030517 21 6 0,000 9,921E-03 0,04379679 ! removal of superoxide radicals GO:0019430 11 6 0,000 9,921E-03 0,04371658 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,921E-03 0,04363666 ! determination of adult lifespan GO:0008340 15 6 0,000 9,921E-03 0,04355703 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 9,921E-03 0,04347769 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 9,921E-03 0,04339864 ! cerebellar cortex formation GO:0021697 8 6 0,000 9,921E-03 0,04331987 ! catecholamine transport GO:0051937 9 6 0,000 9,921E-03 0,0432414 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 9,921E-03 0,0431632 ! sensory cilium assembly GO:0035058 10 6 0,000 9,921E-03 0,04308529 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,921E-03 0,04300766 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 9,921E-03 0,04293031 ! maternal placenta development GO:0001893 12 6 0,000 9,921E-03 0,04285323 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 9,921E-03 0,04277644 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,921E-03 0,04269991 ! negative regulation of B cell activation GO:0050869 13 6 0,000 9,921E-03 0,04262366 ! protein amino acid prenylation GO:0018346 16 6 0,000 9,921E-03 0,04254768 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,921E-03 0,04247198 ! positive regulation of coagulation GO:0050820 12 6 0,000 9,921E-03 0,04239654 ! bone development GO:0060348 189 91 1,000 0,01006735 0,0429469 ! regulation of defense response GO:0031347 149 92 1,000 0,01028024 0,04377747 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,01049513 0,04461358 ! regulation of membrane potential GO:0042391 164 93 1,000 0,01049513 0,04453489 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,01049513 0,04445649 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01093086 0,04622083 ! positive regulation of immune response GO:0050778 156 96 1,000 0,01115169 0,04707188 ! tRNA transcription GO:0009304 14 7 0,000 0,01156477 0,04873001 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01156477 0,04864481 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01156477 0,04855992 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01156477 0,04847532 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01156477 0,04839101 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01156477 0,048307 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01156477 0,04822328 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01156477 0,04813985 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01156477 0,04805671 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01156477 0,04797385 ! prostate gland development GO:0030850 13 7 0,000 0,01156477 0,04789128 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01156477 0,04780899 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01156477 0,04772699 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01156477 0,04764526 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01156477 0,04756382 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01156477 0,04748265 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01156477 0,04740176 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01156477 0,04732115 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01156477 0,0472408 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01156477 0,04716073 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01156477 0,04708094 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01156477 0,04700141 ! glycolipid transport GO:0046836 10 7 0,000 0,01156477 0,04692215 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01156477 0,04684315 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01156477 0,04676443 ! neuron adhesion GO:0007158 12 7 0,000 0,01156477 0,04668596 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01156477 0,04660776 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01156477 0,04652982 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01156477 0,04645214 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01156477 0,04637472 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01156477 0,04629756 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01156477 0,04622065 ! mRNA stabilization GO:0048255 18 7 0,000 0,01156477 0,046144 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01156477 0,0460676 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01156477 0,04599146 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01156477 0,04591557 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01156477 0,04583992 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01156477 0,04576453 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01156477 0,04568938 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01156477 0,04561448 ! lipoprotein transport GO:0042953 14 7 0,000 0,01156477 0,04553983 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01156477 0,04546541 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01156477 0,04539125 ! rhythmic behavior GO:0007622 15 7 0,000 0,01156477 0,04531732 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01156477 0,04524363 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01156477 0,04517018 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01156477 0,04509697 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01156477 0,045024 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01156477 0,04495127 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01156477 0,04487876 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01156477 0,04480649 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01156477 0,04473446 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01156477 0,04466265 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01156477 0,04459108 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01156477 0,04451973 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01156477 0,04444862 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01156477 0,04437772 ! spinal cord patterning GO:0021511 13 7 0,000 0,01156477 0,04430706 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01156477 0,04423662 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01156477 0,0441664 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01156477 0,04409641 ! adrenal gland development GO:0030325 17 7 0,000 0,01156477 0,04402664 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01156477 0,04395708 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01156477 0,04388775 ! ovulation GO:0030728 9 7 0,000 0,01156477 0,04381864 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01156477 0,04374974 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01156477 0,04368106 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01156477 0,04361259 ! microtubule nucleation GO:0007020 20 7 0,000 0,01156477 0,04354434 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01156477 0,0434763 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01156477 0,04340848 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01156477 0,04334086 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01156477 0,04327346 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01156477 0,04320626 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01156477 0,04313928 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01156477 0,0430725 ! galactose metabolic process GO:0006012 13 7 0,000 0,01156477 0,04300592 ! response to dietary excess GO:0002021 8 7 0,000 0,01156477 0,04293956 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01156477 0,04287339 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01156477 0,04280744 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01156477 0,04274168 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01156477 0,04267612 ! organ growth GO:0035265 15 7 0,000 0,01156477 0,04261077 ! purine salvage GO:0043101 10 7 0,000 0,01156477 0,04254562 ! nucleoside transport GO:0015858 8 7 0,000 0,01156477 0,04248066 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01156477 0,0424159 ! parturition GO:0007567 14 7 0,000 0,01156477 0,04235134 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01156477 0,04228698 ! rRNA modification GO:0000154 14 7 0,000 0,01156477 0,04222281 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01156477 0,04215884 ! spindle checkpoint GO:0031577 15 7 0,000 0,01156477 0,04209506 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01156477 0,04203147 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01156477 0,04196807 ! macrophage differentiation GO:0030225 11 7 0,000 0,01156477 0,04190487 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01156477 0,04184185 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01156477 0,04177903 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01156477 0,04171639 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01156477 0,04165394 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01156477 0,04159168 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01156477 0,0415296 ! fibrinolysis GO:0042730 10 7 0,000 0,01156477 0,04146771 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01156477 0,041406 ! eating behavior GO:0042755 7 7 0,000 0,01156477 0,04134448 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01156477 0,04128314 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01156477 0,04122198 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01156477 0,041161 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01156477 0,0411002 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01156477 0,04103958 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01156477 0,04097914 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01156477 0,04091887 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01156477 0,04085879 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01156477 0,04079888 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01156477 0,04073914 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01156477 0,04067958 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01156477 0,04062019 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01156477 0,04056098 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01156477 0,04050194 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01156477 0,04044307 ! regulation of meiosis GO:0040020 12 7 0,000 0,01156477 0,04038437 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01156477 0,04032585 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01156477 0,04026749 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01156477 0,0402093 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01156477 0,04015127 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01156477 0,04009342 ! transcription termination GO:0006353 13 7 0,000 0,01156477 0,04003573 ! response to tumor cell GO:0002347 13 7 0,000 0,01156477 0,03997821 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01156477 0,03992085 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01156477 0,03986366 ! anaphase GO:0051322 17 7 0,000 0,01156477 0,03980663 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01156477 0,03974976 ! axonal fasciculation GO:0007413 18 7 0,000 0,01156477 0,03969306 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01156477 0,03963651 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01156477 0,03958013 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01156477 0,03952391 ! diuresis GO:0030146 12 7 0,000 0,01156477 0,03946785 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01156477 0,03941195 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01156477 0,0393562 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01156477 0,03930061 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01156477 0,03924518 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01156477 0,03918991 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01156477 0,03913479 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01156477 0,03907982 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01156477 0,03902501 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01156477 0,03897035 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01156477 0,03891585 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01156477 0,0388615 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01156477 0,0388073 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01156477 0,03875325 ! lymph node development GO:0048535 10 7 0,000 0,01156477 0,03869935 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01156477 0,0386456 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01156477 0,038592 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01156477 0,03853855 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01156477 0,03848525 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01156477 0,03843209 ! adult feeding behavior GO:0008343 9 7 0,000 0,01156477 0,03837908 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01156477 0,03832622 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01156477 0,0382735 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01156477 0,03822092 ! muscle adaptation GO:0043500 14 7 0,000 0,01156477 0,0381685 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01156477 0,03811621 ! retina homeostasis GO:0001895 12 7 0,000 0,01156477 0,03806407 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01156477 0,03801207 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01156477 0,03796021 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01156477 0,03790849 ! protein prenylation GO:0018342 18 7 0,000 0,01156477 0,03785692 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01156477 0,03780548 ! interphase GO:0051325 213 98 1,000 0,01159925 0,03786675 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,01182596 0,03855456 GO:0060538|skeletal muscle organ development, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01320614 0,04299591 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01320614 0,04293781 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01320614 0,04287986 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01320614 0,04282207 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01320614 0,04276444 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01320614 0,04270696 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01320614 0,04264964 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01320614 0,04259246 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01320614 0,04253545 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01320614 0,04247858 ! meiotic prophase I GO:0007128 13 8 0,000 0,01320614 0,04242187 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01320614 0,0423653 ! oligopeptide transport GO:0006857 15 8 0,000 0,01320614 0,04230889 ! UTP metabolic process GO:0046051 8 8 0,000 0,01320614 0,04225263 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01320614 0,04219652 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01320614 0,04214055 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01320614 0,04208474 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01320614 0,04202907 ! succinate metabolic process GO:0006105 14 8 0,000 0,01320614 0,04197355 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01320614 0,04191818 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01320614 0,04186295 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01320614 0,04180787 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01320614 0,04175293 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01320614 0,04169813 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01320614 0,04164348 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01320614 0,04158898 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01320614 0,04153461 ! reflex GO:0060004 16 8 0,000 0,01320614 0,04148039 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01320614 0,04142631 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01320614 0,04137237 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01320614 0,04131857 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01320614 0,04126491 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01320614 0,04121139 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01320614 0,041158 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01320614 0,04110476 ! pigment granule organization GO:0048753 16 8 0,000 0,01320614 0,04105165 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01320614 0,04099868 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01320614 0,04094585 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01320614 0,04089315 ! histidine metabolic process GO:0006547 16 8 0,000 0,01320614 0,04084059 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01320614 0,04078816 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01320614 0,04073587 ! glycine catabolic process GO:0006546 13 8 0,000 0,01320614 0,04068371 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01320614 0,04063169 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01320614 0,04057979 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01320614 0,04052803 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01320614 0,04047641 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01320614 0,04042491 ! melanin metabolic process GO:0006582 15 8 0,000 0,01320614 0,04037354 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01320614 0,04032231 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01320614 0,0402712 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01320614 0,04022023 ! macrophage activation GO:0042116 12 8 0,000 0,01320614 0,04016938 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01320614 0,04011866 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01320614 0,04006807 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01320614 0,04001761 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01320614 0,03996727 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01320614 0,03991706 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01320614 0,03986697 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01320614 0,03981702 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01320614 0,03976718 ! osteoblast development GO:0002076 16 8 0,000 0,01320614 0,03971747 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01320614 0,03966789 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01320614 0,03961843 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01320614 0,03956909 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01320614 0,03951987 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01320614 0,03947078 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01320614 0,03942181 ! response to UV-B GO:0010224 16 8 0,000 0,01320614 0,03937296 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01320614 0,03932423 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01320614 0,03927562 ! intermediate filament organization GO:0045109 12 8 0,000 0,01320614 0,03922713 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01320614 0,03917877 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01320614 0,03913052 ! cellular extravasation GO:0045123 12 8 0,000 0,01320614 0,03908238 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01320614 0,03903437 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01320614 0,03898648 ! response to antibiotic GO:0046677 11 8 0,000 0,01320614 0,0389387 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01320614 0,03889104 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01320614 0,03884349 ! DNA topological change GO:0006265 12 8 0,000 0,01320614 0,03879607 ! response to tropane GO:0014073 15 8 0,000 0,01320614 0,03874875 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01320614 0,03870156 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01320614 0,03865447 ! melanosome transport GO:0032402 13 8 0,000 0,01320614 0,03860751 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01320614 0,03856065 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01320614 0,03851391 ! mast cell activation GO:0045576 14 8 0,000 0,01320614 0,03846729 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01320614 0,03842077 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01320614 0,03837437 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01320614 0,03832808 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01320614 0,0382819 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01320614 0,03823583 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01320614 0,03818988 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01320614 0,03814403 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01320614 0,0380983 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01320614 0,03805267 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01320614 0,03800715 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01320614 0,03796174 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01320614 0,03791644 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01320614 0,03787125 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01320614 0,03782616 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01320614 0,03778119 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01320614 0,03773632 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01320614 0,03769155 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01320614 0,03764689 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01320614 0,03760234 ! hormone catabolic process GO:0042447 17 8 0,000 0,01320614 0,03755789 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01320614 0,03751355 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01320614 0,03746931 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01320614 0,03742518 ! ATP catabolic process GO:0006200 11 8 0,000 0,01320614 0,03738115 ! blastocyst growth GO:0001832 19 8 0,000 0,01320614 0,03733722 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01320614 0,0372934 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01320614 0,03724968 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01320614 0,03720606 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01320614 0,03716255 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01320614 0,03711913 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01320614 0,03707582 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01320614 0,03703261 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01320614 0,0369895 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01320614 0,03694649 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01320614 0,03690358 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01320614 0,03686076 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01320614 0,03681805 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01320614 0,03677544 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01320614 0,03673292 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01320614 0,03669051 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01320614 0,03664819 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01320614 0,03660597 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01484484 0,04110092 ! axon extension GO:0048675 15 9 0,000 0,01484484 0,04105367 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01484484 0,04100654 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01484484 0,04095951 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01484484 0,0409126 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01484484 0,04086579 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01484484 0,04081908 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01484484 0,04077248 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01484484 0,04072599 ! phosphate transport GO:0006817 19 9 0,000 0,01484484 0,04067961 ! reproductive behavior GO:0019098 19 9 0,000 0,01484484 0,04063333 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01484484 0,04058716 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01484484 0,04054109 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01484484 0,04049512 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01484484 0,04044926 ! GTP metabolic process GO:0046039 9 9 0,000 0,01484484 0,0404035 ! RNA methylation GO:0001510 15 9 0,000 0,01484484 0,04035785 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01484484 0,0403123 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01484484 0,04026685 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01484484 0,04022151 ! artery development GO:0060840 24 9 0,000 0,01484484 0,04017626 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01484484 0,04013112 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01484484 0,04008608 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01484484 0,04004114 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01484484 0,0399963 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01484484 0,03995156 ! chemosensory behavior GO:0007635 20 9 0,000 0,01484484 0,03990692 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01484484 0,03986238 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01484484 0,03981794 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01484484 0,0397736 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01484484 0,03972936 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01484484 0,03968522 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01484484 0,03964117 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01484484 0,03959722 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01484484 0,03955337 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01484484 0,03950962 ! protein targeting to ER GO:0045047 22 9 0,000 0,01484484 0,03946596 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01484484 0,0394224 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01484484 0,03937894 ! T cell selection GO:0045058 23 9 0,000 0,01484484 0,03933557 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01484484 0,0392923 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01484484 0,03924912 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01484484 0,03920603 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01484484 0,03916304 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01484484 0,03912015 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01484484 0,03907735 ! mannose metabolic process GO:0006013 13 9 0,000 0,01484484 0,03903464 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01484484 0,03899203 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01484484 0,03894951 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01484484 0,03890708 ! receptor clustering GO:0043113 18 9 0,000 0,01484484 0,03886474 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01484484 0,0388225 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01484484 0,03878034 ! ruffle organization GO:0031529 15 9 0,000 0,01484484 0,03873828 ! retinol metabolic process GO:0042572 18 9 0,000 0,01484484 0,03869631 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01484484 0,03865443 ! behavioral fear response GO:0001662 22 9 0,000 0,01484484 0,03861264 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01484484 0,03857095 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01484484 0,03852934 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01484484 0,03848782 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01484484 0,03844639 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01484484 0,03840505 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01484484 0,0383638 ! segment specification GO:0007379 13 9 0,000 0,01484484 0,03832264 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01484484 0,03828156 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01484484 0,03824057 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01484484 0,03819968 ! response to amine stimulus GO:0014075 13 9 0,000 0,01484484 0,03815886 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01484484 0,03811814 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01484484 0,0380775 ! erythrocyte development GO:0048821 15 9 0,000 0,01484484 0,03803695 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01484484 0,03799649 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01484484 0,03795611 ! renal water homeostasis GO:0003091 14 9 0,000 0,01484484 0,03791581 ! postreplication repair GO:0006301 22 9 0,000 0,01484484 0,03787561 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01484484 0,03783548 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01484484 0,03779545 ! icosanoid secretion GO:0032309 15 9 0,000 0,01484484 0,03775549 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01484484 0,03771562 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01484484 0,03767584 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01484484 0,03763614 ! regulation of cell division GO:0051302 15 9 0,000 0,01484484 0,03759652 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01484484 0,03755699 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01484484 0,03751754 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01484484 0,03747817 ! sterol catabolic process GO:0016127 11 9 0,000 0,01484484 0,03743889 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01484484 0,03739968 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01484484 0,03736056 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01484484 0,03732152 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01484484 0,03728256 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01484484 0,03724369 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01484484 0,03720489 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01484484 0,03716618 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01484484 0,03712754 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01484484 0,03708899 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01484484 0,03705052 ! purine base metabolic process GO:0006144 21 9 0,000 0,01484484 0,03701212 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01484484 0,03697381 ! pigment granule transport GO:0051904 17 9 0,000 0,01484484 0,03693557 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01484484 0,03689741 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01484484 0,03685934 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01484484 0,03682134 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01484484 0,03678342 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01484484 0,03674557 ! mitochondrion localization GO:0051646 15 9 0,000 0,01484484 0,03670781 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01648088 0,0407115 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01648088 0,04066974 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01648088 0,04062807 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01648088 0,04058649 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01648088 0,04054499 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01648088 0,04050357 ! synapsis GO:0007129 13 10 0,000 0,01648088 0,04046224 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01648088 0,040421 ! N-glycan processing GO:0006491 20 10 0,000 0,01648088 0,04037984 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01648088 0,04033876 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01648088 0,04029776 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01648088 0,04025685 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01648088 0,04021602 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01648088 0,04017528 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01648088 0,04013461 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01648088 0,04009403 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01648088 0,04005353 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01648088 0,04001312 ! androgen metabolic process GO:0008209 17 10 0,000 0,01648088 0,03997278 ! phospholipid efflux GO:0033700 16 10 0,000 0,01648088 0,03993253 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01648088 0,03989235 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01648088 0,03985226 ! lung alveolus development GO:0048286 26 10 0,000 0,01648088 0,03981225 ! pathogenesis GO:0009405 13 10 0,000 0,01648088 0,03977232 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01648088 0,03973246 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01648088 0,03969269 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01648088 0,039653 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01648088 0,03961338 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01648088 0,03957385 ! endoderm development GO:0007492 16 10 0,000 0,01648088 0,03953439 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01648088 0,03949502 ! arginine catabolic process GO:0006527 13 10 0,000 0,01648088 0,03945572 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01648088 0,0394165 ! proline metabolic process GO:0006560 13 10 0,000 0,01648088 0,03937736 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01648088 0,03933829 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01648088 0,0392993 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01648088 0,03926039 ! V(D)J recombination GO:0033151 28 10 0,000 0,01648088 0,03922156 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01648088 0,0391828 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01648088 0,03914412 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01648088 0,03910552 ! B cell proliferation GO:0042100 18 10 0,000 0,01648088 0,03906699 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01648088 0,03902854 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01648088 0,03899017 ! multicellular organism growth GO:0035264 18 10 0,000 0,01648088 0,03895186 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01648088 0,03891364 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01648088 0,03887549 ! epithelial cell development GO:0002064 20 10 0,000 0,01648088 0,03883741 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01648088 0,03879941 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01648088 0,03876148 ! macroautophagy GO:0016236 17 10 0,000 0,01648088 0,03872363 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01648088 0,03868585 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01648088 0,03864815 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01648088 0,03861051 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01648088 0,03857296 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01648088 0,03853547 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01648088 0,03849806 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01648088 0,03846072 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01648088 0,03842345 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01648088 0,03838625 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01648088 0,03834913 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01648088 0,03831208 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01648088 0,03827509 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01648088 0,03823819 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01648088 0,03820135 ! response to dsRNA GO:0043331 20 10 0,000 0,01648088 0,03816458 ! DNA ligation GO:0006266 19 10 0,000 0,01648088 0,03812788 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01648088 0,03809126 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01648088 0,0380547 ! melanosome localization GO:0032400 16 10 0,000 0,01648088 0,03801821 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01648088 0,0379818 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01648088 0,03794545 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01648088 0,03790918 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01648088 0,03787297 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01648088 0,03783683 ! mRNA cleavage GO:0006379 17 10 0,000 0,01648088 0,03780076 ! protein sumoylation GO:0016925 15 10 0,000 0,01648088 0,03776476 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01648088 0,03772883 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01648088 0,03769296 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01648088 0,03765717 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01648088 0,03762144 ! salivary gland development GO:0007431 27 10 0,000 0,01648088 0,03758578 ! prophase GO:0051324 15 10 0,000 0,01648088 0,03755019 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01648088 0,03751466 ! apical protein localization GO:0045176 15 10 0,000 0,01648088 0,0374792 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01648088 0,03744381 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01648088 0,03740849 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01648088 0,03737323 ! midbrain development GO:0030901 13 10 0,000 0,01648088 0,03733804 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01648088 0,03730291 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01648088 0,03726786 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01648088 0,03723286 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01648088 0,03719793 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01648088 0,03716307 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01648088 0,03712828 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01648088 0,03709354 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01648088 0,03705888 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01648088 0,03702427 ! oocyte development GO:0048599 17 10 0,000 0,01648088 0,03698974 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01648088 0,03695526 ! blastocyst formation GO:0001825 17 10 0,000 0,01648088 0,03692085 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01648088 0,03688651 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01648088 0,03685223 ! activation of innate immune response GO:0002218 12 10 0,000 0,01648088 0,03681801 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01648088 0,03678386 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01648088 0,03674977 ! response to nicotine GO:0035094 20 10 0,000 0,01648088 0,03671574 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01648088 0,03668177 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01648088 0,03664787 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01648088 0,03661403 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01811425 0,04020562 ! respiratory burst GO:0045730 17 11 0,000 0,01811425 0,04016857 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01811425 0,04013158 ! neuron fate specification GO:0048665 17 11 0,000 0,01811425 0,04009466 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01811425 0,04005781 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01811425 0,04002102 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01811425 0,03998431 ! thyroid gland development GO:0030878 26 11 0,000 0,01811425 0,03994766 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01811425 0,03991107 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01811425 0,03987456 ! response to pain GO:0048265 24 11 0,000 0,01811425 0,03983811 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01811425 0,03980173 ! T cell proliferation GO:0042098 26 11 0,000 0,01811425 0,03976541 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01811425 0,03972916 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01811425 0,03969298 ! bone resorption GO:0045453 16 11 0,000 0,01811425 0,03965686 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01811425 0,03962081 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01811425 0,03958483 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01811425 0,0395489 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01811425 0,03951305 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01811425 0,03947726 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01811425 0,03944153 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01811425 0,03940587 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01811425 0,03937027 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01811425 0,03933474 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01811425 0,03929927 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01811425 0,03926387 ! lipid digestion GO:0044241 18 11 0,000 0,01811425 0,03922853 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01811425 0,03919325 ! UV protection GO:0009650 19 11 0,000 0,01811425 0,03915804 ! adult heart development GO:0007512 14 11 0,000 0,01811425 0,03912288 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01811425 0,0390878 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01811425 0,03905277 ! temperature homeostasis GO:0001659 17 11 0,000 0,01811425 0,03901781 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01811425 0,03898291 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01811425 0,03894807 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01811425 0,0389133 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01811425 0,03887858 ! regulation of organ growth GO:0046620 13 11 0,000 0,01811425 0,03884393 ! pigment granule localization GO:0051875 20 11 0,000 0,01811425 0,03880934 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01811425 0,03877482 ! vasoconstriction GO:0042310 18 11 0,000 0,01811425 0,03874035 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01811425 0,03870594 ! embryonic axis specification GO:0000578 18 11 0,000 0,01811425 0,0386716 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01811425 0,03863732 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01811425 0,03860309 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01811425 0,03856893 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01811425 0,03853483 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01811425 0,03850079 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01811425 0,03846681 ! zymogen activation GO:0031638 15 11 0,000 0,01811425 0,03843289 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01811425 0,03839902 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01811425 0,03836522 ! nucleosome positioning GO:0016584 15 11 0,000 0,01811425 0,03833148 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01811425 0,0382978 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01811425 0,03826417 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01811425 0,03823061 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01811425 0,0381971 ! acid secretion GO:0046717 18 11 0,000 0,01811425 0,03816365 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01811425 0,03813027 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01811425 0,03809693 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01811425 0,03806366 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01811425 0,03803045 ! oocyte differentiation GO:0009994 18 11 0,000 0,01811425 0,03799729 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01811425 0,03796419 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01811425 0,03793115 ! cholesterol efflux GO:0033344 19 11 0,000 0,01811425 0,03789817 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01811425 0,03786524 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01811425 0,03783237 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01811425 0,03779956 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01811425 0,03776681 ! embryonic gut development GO:0048566 15 11 0,000 0,01811425 0,03773411 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01811425 0,03770146 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01811425 0,03766888 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01811425 0,03763635 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01811425 0,03760388 ! defense response to fungus GO:0050832 13 11 0,000 0,01811425 0,03757146 ! developmental induction GO:0031128 19 11 0,000 0,01811425 0,0375391 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01811425 0,03750679 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01811425 0,03747454 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01811425 0,03744235 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01811425 0,03741021 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01811425 0,03737812 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01811425 0,0373461 ! nucleus localization GO:0051647 19 11 0,000 0,01811425 0,03731412 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01811425 0,0372822 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01974497 0,04060375 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01974497 0,04056908 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01974497 0,04053446 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01974497 0,04049991 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01974497 0,04046541 ! virus-host interaction GO:0019048 29 12 0,000 0,01974497 0,04043097 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01974497 0,04039659 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01974497 0,04036227 ! cartilage condensation GO:0001502 20 12 0,000 0,01974497 0,04032801 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01974497 0,0402938 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01974497 0,04025965 ! protein complex disassembly GO:0043241 27 12 0,000 0,01974497 0,04022556 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01974497 0,04019153 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01974497 0,04015756 ! hippocampus development GO:0021766 26 12 0,000 0,01974497 0,04012364 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01974497 0,04008978 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01974497 0,04005598 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01974497 0,04002223 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01974497 0,03998855 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01974497 0,03995491 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01974497 0,03992134 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01974497 0,03988782 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01974497 0,03985436 ! drug transport GO:0015893 16 12 0,000 0,01974497 0,03982095 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01974497 0,0397876 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01974497 0,0397543 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01974497 0,03972106 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01974497 0,03968788 ! focal adhesion formation GO:0048041 35 12 0,000 0,01974497 0,03965475 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01974497 0,03962168 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01974497 0,03958866 ! forebrain cell migration GO:0021885 21 12 0,000 0,01974497 0,0395557 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01974497 0,03952279 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01974497 0,03948994 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01974497 0,03945714 ! entry into host cell GO:0030260 32 12 0,000 0,01974497 0,03942439 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01974497 0,0393917 ! monoamine transport GO:0015844 18 12 0,000 0,01974497 0,03935907 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01974497 0,03932648 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01974497 0,03929396 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01974497 0,03926148 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01974497 0,03922906 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01974497 0,03919669 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01974497 0,03916438 ! protein homotetramerization GO:0051289 21 12 0,000 0,01974497 0,03913212 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01974497 0,03909991 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01974497 0,03906776 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01974497 0,03903565 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01974497 0,03900361 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01974497 0,03897161 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01974497 0,03893967 ! cranial nerve development GO:0021545 20 12 0,000 0,01974497 0,03890777 ! fucose catabolic process GO:0019317 22 12 0,000 0,01974497 0,03887593 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01974497 0,03884415 ! histone acetylation GO:0016573 26 12 0,000 0,01974497 0,03881241 ! histone methylation GO:0016571 26 12 0,000 0,01974497 0,03878073 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01974497 0,0387491 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01974497 0,03871752 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01974497 0,03868599 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01974497 0,03865451 ! T cell homeostasis GO:0043029 25 12 0,000 0,01974497 0,03862308 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01974497 0,03859171 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01974497 0,03856038 ! spleen development GO:0048536 22 12 0,000 0,01974497 0,03852911 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01974497 0,03849789 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01974497 0,03846671 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01974497 0,03843559 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01974497 0,03840452 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01974497 0,0383735 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01974497 0,03834253 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01974497 0,03831161 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01974497 0,03828073 ! response to cold GO:0009409 17 12 0,000 0,01974497 0,03824991 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01974497 0,03821914 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01974497 0,03818842 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02137303 0,04130402 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02137303 0,04127087 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02137303 0,04123777 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02137303 0,04120473 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02137303 0,04117174 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02137303 0,0411388 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02137303 0,04110592 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02137303 0,04107309 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02137303 0,04104031 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02137303 0,04100758 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02137303 0,0409749 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02137303 0,04094228 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02137303 0,04090971 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02137303 0,04087719 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02137303 0,04084472 ! methionine metabolic process GO:0006555 27 13 0,000 0,02137303 0,04081231 ! plasma membrane organization GO:0007009 24 13 0,000 0,02137303 0,04077994 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02137303 0,04074763 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02137303 0,04071536 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02137303 0,04068315 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02137303 0,04065099 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02137303 0,04061888 ! response to X-ray GO:0010165 25 13 0,000 0,02137303 0,04058682 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02137303 0,04055481 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02137303 0,04052286 ! exocrine system development GO:0035272 32 13 0,000 0,02137303 0,04049095 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02137303 0,04045909 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02137303 0,04042728 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02137303 0,04039553 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02137303 0,04036382 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02137303 0,04033216 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02137303 0,04030055 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02137303 0,04026899 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02137303 0,04023748 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02137303 0,04020602 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02137303 0,04017461 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02137303 0,04014325 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02137303 0,04011194 ! ribosome assembly GO:0042255 17 13 0,000 0,02137303 0,04008067 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02137303 0,04004946 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02137303 0,04001829 ! chromatin silencing GO:0006342 26 13 0,000 0,02137303 0,03998717 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02137303 0,0399561 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02137303 0,03992508 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02137303 0,03989411 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02137303 0,03986318 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02137303 0,0398323 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02137303 0,03980147 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02137303 0,03977069 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02137303 0,03973996 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02137303 0,03970927 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02137303 0,03967863 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02137303 0,03964804 ! embryonic placenta development GO:0001892 23 13 0,000 0,02137303 0,03961749 ! insulin secretion GO:0030073 23 13 0,000 0,02137303 0,03958699 ! actin filament polymerization GO:0030041 24 13 0,000 0,02137303 0,03955654 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02137303 0,03952614 ! acrosome reaction GO:0007340 18 13 0,000 0,02137303 0,03949578 ! rRNA transcription GO:0009303 25 14 0,000 0,02299844 0,0424668 ! lactation GO:0007595 26 14 0,000 0,02299844 0,04243423 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02299844 0,04240172 ! reproductive cellular process GO:0048610 20 14 0,000 0,02299844 0,04236925 ! tRNA modification GO:0006400 20 14 0,000 0,02299844 0,04233683 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02299844 0,04230447 ! regulation of S phase GO:0033261 23 14 0,000 0,02299844 0,04227215 ! water transport GO:0006833 21 14 0,000 0,02299844 0,04223988 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02299844 0,04220766 ! non-recombinational repair GO:0000726 25 14 0,000 0,02299844 0,04217549 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02299844 0,04214337 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02299844 0,0421113 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02299844 0,04207927 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02299844 0,0420473 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02299844 0,04201537 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02299844 0,04198349 ! palate development GO:0060021 31 14 0,000 0,02299844 0,04195166 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02299844 0,04191988 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02299844 0,04188815 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02299844 0,04185646 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02299844 0,04182482 ! arginine metabolic process GO:0006525 17 14 0,000 0,02299844 0,04179323 ! regulation of heart rate GO:0002027 24 14 0,000 0,02299844 0,04176169 ! organic alcohol transport GO:0015850 29 14 0,000 0,02299844 0,0417302 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02299844 0,04169875 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02299844 0,04166735 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02299844 0,041636 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02299844 0,04160469 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02299844 0,04157343 ! L-amino acid transport GO:0015807 30 14 0,000 0,02299844 0,04154222 ! bone mineralization GO:0030282 17 14 0,000 0,02299844 0,04151106 ! stem cell development GO:0048864 43 14 0,000 0,02299844 0,04147994 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02299844 0,04144887 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02299844 0,04141785 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02299844 0,04138687 ! cerebellum development GO:0021549 21 14 0,000 0,02299844 0,04135594 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02299844 0,04132505 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02299844 0,04129421 ! response to gamma radiation GO:0010332 28 14 0,000 0,02299844 0,04126342 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02299844 0,04123267 ! cofactor transport GO:0051181 26 14 0,000 0,02299844 0,04120197 ! NADP metabolic process GO:0006739 24 14 0,000 0,02299844 0,04117131 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02299844 0,0411407 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02299844 0,04111013 ! intestinal absorption GO:0050892 25 14 0,000 0,02299844 0,04107962 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02299844 0,04104914 ! oxygen transport GO:0015671 21 14 0,000 0,02299844 0,04101871 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02299844 0,04098833 ! male genitalia development GO:0030539 24 14 0,000 0,02299844 0,04095799 ! regulation of axon extension GO:0030516 37 14 0,000 0,02299844 0,04092769 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02299844 0,04089744 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02299844 0,04086724 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0246212 0,04371853 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0246212 0,04368629 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0246212 0,0436541 ! superoxide anion generation GO:0042554 20 15 0,000 0,0246212 0,04362195 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0246212 0,04358985 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0246212 0,0435578 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0246212 0,0435258 ! copper ion transport GO:0006825 20 15 0,000 0,0246212 0,04349384 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0246212 0,04346193 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0246212 0,04343007 ! sulfate transport GO:0008272 23 15 0,000 0,0246212 0,04339825 ! response to cAMP GO:0051591 22 15 0,000 0,0246212 0,04336648 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0246212 0,04333476 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0246212 0,04330308 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0246212 0,04327145 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0246212 0,04323986 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0246212 0,04320832 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0246212 0,04317683 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0246212 0,04314538 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0246212 0,04311398 ! pituitary gland development GO:0021983 29 15 0,000 0,0246212 0,04308263 ! vesicle coating GO:0006901 33 15 0,000 0,0246212 0,04305132 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0246212 0,04302005 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0246212 0,04298883 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0246212 0,04295766 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0246212 0,04292653 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0246212 0,04289545 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0246212 0,04286441 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0246212 0,04283341 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0246212 0,04280247 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0246212 0,04277156 ! histone deacetylation GO:0016575 20 15 0,000 0,0246212 0,0427407 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0246212 0,04270989 ! tissue regeneration GO:0042246 26 15 0,000 0,0246212 0,04267912 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0246212 0,04264839 ! water homeostasis GO:0030104 27 15 0,000 0,0246212 0,04261771 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0246212 0,04258707 ! muscle maintenance GO:0046716 26 15 0,000 0,0246212 0,04255647 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0246212 0,04252592 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0246212 0,04249542 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0246212 0,04246496 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0246212 0,04243454 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0246212 0,04240416 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0246212 0,04237383 ! detection of bacterium GO:0016045 18 15 0,000 0,0246212 0,04234354 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0246212 0,04231329 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0246212 0,04228309 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0246212 0,04225293 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0246212 0,04222282 ! peptide hormone processing GO:0016486 23 15 0,000 0,0246212 0,04219274 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02624133 0,0449371 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02624133 0,04490514 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02624133 0,04487323 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02624133 0,04484136 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02624133 0,04480953 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02624133 0,04477775 ! bone remodeling GO:0046849 27 16 0,000 0,02624133 0,04474602 ! filopodium assembly GO:0046847 32 16 0,000 0,02624133 0,04471433 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02624133 0,04468268 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02624133 0,04465108 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02624133 0,04461953 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02624133 0,04458801 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02624133 0,04455655 ! startle response GO:0001964 28 16 0,000 0,02624133 0,04452513 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02624133 0,04449375 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02624133 0,04446241 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02624133 0,04443113 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02624133 0,04439988 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02624133 0,04436868 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02624133 0,04433752 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02624133 0,04430641 ! response to osmotic stress GO:0006970 25 16 0,000 0,02624133 0,04427534 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02624133 0,04424431 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02624133 0,04421333 ! fructose metabolic process GO:0006000 25 16 0,000 0,02624133 0,04418239 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02624133 0,04415149 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02624133 0,04412063 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02624133 0,04408982 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02624133 0,04405906 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02624133 0,04402833 ! axon cargo transport GO:0008088 43 16 0,000 0,02624133 0,04399765 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02624133 0,04396701 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02624133 0,04393642 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02624133 0,04390586 ! DNA replication initiation GO:0006270 27 16 0,000 0,02624133 0,04387535 ! neuron recognition GO:0008038 35 16 0,000 0,02624133 0,04384488 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02624133 0,04381445 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02624133 0,04378407 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02624133 0,04375373 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02624133 0,04372343 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02624133 0,04369317 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02624133 0,04366295 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02624133 0,04363278 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02624133 0,04360264 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02624133 0,04357255 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02624133 0,0435425 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02624133 0,04351249 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02624133 0,04348253 ! defense response to virus GO:0051607 37 16 0,000 0,02624133 0,0434526 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02785881 0,04609924 ! metencephalon development GO:0022037 30 17 0,000 0,02785881 0,04606756 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02785881 0,04603592 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02785881 0,04600432 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02785881 0,04597277 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02785881 0,04594126 ! signal complex assembly GO:0007172 41 17 0,000 0,02785881 0,04590979 ! endothelial cell migration GO:0043542 28 17 0,000 0,02785881 0,04587837 ! inositol metabolic process GO:0006020 28 17 0,000 0,02785881 0,04584699 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02785881 0,04581565 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02785881 0,04578436 ! glial cell development GO:0021782 27 17 0,000 0,02785881 0,04575311 ! limbic system development GO:0021761 36 17 0,000 0,02785881 0,0457219 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02785881 0,04569073 ! adult walking behavior GO:0007628 33 17 0,000 0,02785881 0,0456596 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02785881 0,04562852 ! heart looping GO:0001947 30 17 0,000 0,02785881 0,04559748 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02785881 0,04556648 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02785881 0,04553553 ! myoblast differentiation GO:0045445 45 17 0,000 0,02785881 0,04550462 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02785881 0,04547374 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02785881 0,04544291 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02785881 0,04541213 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02785881 0,04538138 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02785881 0,04535068 ! glycine metabolic process GO:0006544 28 17 0,000 0,02785881 0,04532001 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02785881 0,04528939 ! NAD metabolic process GO:0019674 29 17 0,000 0,02785881 0,04525881 ! membrane budding GO:0006900 37 17 0,000 0,02785881 0,04522827 ! DNA integration GO:0015074 29 17 0,000 0,02785881 0,04519777 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02785881 0,04516732 ! regulation of protein binding GO:0043393 33 17 0,000 0,02785881 0,0451369 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02785881 0,04510653 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02785881 0,04507619 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02785881 0,0450459 ! genitalia development GO:0048806 30 17 0,000 0,02785881 0,04501565 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02785881 0,04498544 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02785881 0,04495526 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02785881 0,04492513 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02785881 0,04489504 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02785881 0,04486499 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02785881 0,04483498 ! steroid catabolic process GO:0006706 31 17 0,000 0,02785881 0,04480501 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02785881 0,04477508 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02785881 0,04474519 ! gas transport GO:0015669 25 17 0,000 0,02785881 0,04471534 ! organic cation transport GO:0015695 31 17 0,000 0,02785881 0,04468553 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02785881 0,04465576 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02785881 0,04462603 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02785881 0,04459634 ! microspike assembly GO:0030035 36 17 0,000 0,02785881 0,04456669 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02785881 0,04453708 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02785881 0,0445075 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02947366 0,04705616 ! neuron maturation GO:0042551 42 18 0,000 0,02947366 0,04702496 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02947366 0,04699379 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02947366 0,04696267 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02947366 0,04693159 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02947366 0,04690055 ! memory GO:0007613 31 18 0,000 0,02947366 0,04686955 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02947366 0,0468386 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02947366 0,04680768 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02947366 0,0467768 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02947366 0,04674597 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02947366 0,04671517 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02947366 0,04668442 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02947366 0,04665371 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02947366 0,04662303 ! response to retinoic acid GO:0032526 26 18 0,000 0,02947366 0,0465924 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02947366 0,04656181 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,02947366 0,04653126 ! response to fungus GO:0009620 21 18 0,000 0,02947366 0,04650074 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02947366 0,04647027 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02947366 0,04643984 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02947366 0,04640945 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02947366 0,04637909 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02947366 0,04634878 ! vitamin transport GO:0051180 27 18 0,000 0,02947366 0,04631851 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02947366 0,04628827 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02947366 0,04625808 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02947366 0,04622792 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02947366 0,04619781 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02947366 0,04616773 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02947366 0,04613769 ! nerve development GO:0021675 28 18 0,000 0,02947366 0,04610769 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02947366 0,04607773 ! protein secretion GO:0009306 39 19 0,000 0,03108589 0,04856665 ! positive regulation of translation GO:0045727 30 19 0,000 0,03108589 0,04853514 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03108589 0,04850366 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03108589 0,04847223 ! skin development GO:0043588 36 19 0,000 0,03108589 0,04844083 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03108589 0,04840948 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03108589 0,04837817 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03108589 0,04834689 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03108589 0,04831566 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03108589 0,04828447 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03108589 0,04825332 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03108589 0,04822221 ! cerebral cortex development GO:0021987 36 19 0,000 0,03108589 0,04819114 ! pigmentation during development GO:0048066 41 19 0,000 0,03108589 0,04816011 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03108589 0,04812911 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03108589 0,04809816 ! heme metabolic process GO:0042168 36 19 0,000 0,03108589 0,04806725 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03108589 0,04803638 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03108589 0,04800555 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03108589 0,04797476 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03108589 0,047944 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03108589 0,04791329 ! peptide cross-linking GO:0018149 37 19 0,000 0,03108589 0,04788261 ! protein export from nucleus GO:0006611 36 19 0,000 0,03108589 0,04785198 ! heart process GO:0003015 30 19 0,000 0,03108589 0,04782138 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03108589 0,04779083 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03108589 0,04776031 ! visual learning GO:0008542 36 19 0,000 0,03108589 0,04772983 ! cellular pigmentation GO:0033059 36 19 0,000 0,03108589 0,04769939 ! G1 phase GO:0051318 40 19 0,000 0,03108589 0,04766899 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03108589 0,04763863 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03108589 0,0476083 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03108589 0,04757802 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03108589 0,04754777 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03108589 0,04751756 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03108589 0,04748739 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03108589 0,04745726 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03108589 0,04742717 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03108589 0,04739711 ! cilium assembly GO:0042384 37 19 0,000 0,03108589 0,0473671 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03108589 0,04733712 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03269549 0,0497567 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03269549 0,04972525 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03269549 0,04969383 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03269549 0,04966246 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03269549 0,04963113 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03269549 0,04959984 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,03269549 0,04956858 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03269549 0,04953737 ! response to vitamin GO:0033273 31 20 0,000 0,03269549 0,04950619 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03269549 0,04947506 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03269549 0,04944396 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03269549 0,0494129 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03269549 0,04938188 ! response to alkaloid GO:0043279 38 20 0,000 0,03269549 0,0493509 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03269549 0,04931996 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03269549 0,04928906 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03269549 0,0492582 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03269549 0,04922737 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03269549 0,04919658 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03269549 0,04916584 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03269549 0,04913513 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03269549 0,04910446 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03269549 0,04907382 ! body fluid secretion GO:0007589 31 20 0,000 0,03269549 0,04904323 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03269549 0,04901267 ! peptide secretion GO:0002790 35 20 0,000 0,03269549 0,04898215 ! stem cell differentiation GO:0048863 53 20 0,000 0,03269549 0,04895167 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03269549 0,04892123 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03269549 0,04889083 ! sensory perception of pain GO:0019233 30 20 0,000 0,03269549 0,04886046 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03269549 0,04883013 ! diencephalon development GO:0021536 34 20 0,000 0,03269549 0,04879984 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03269549 0,04876958 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03269549 0,04873937 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03269549 0,04870919 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03269549 0,04867905 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03269549 0,04864894 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03269549 0,04861887 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03269549 0,04858884 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03269549 0,04855885 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03269549 0,04852889 ! regulation of glucose import GO:0046324 29 20 0,000 0,03269549 0,04849898 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03269549 0,04846909 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03269549 0,04843925 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03269549 0,04840944 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03269549 0,04837967 ! negative regulation of translation GO:0017148 29 20 0,000 0,03269549 0,04834993 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03269549 0,04832023 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03269549 0,04829057 ! regulation of cell killing GO:0031341 42 21 0,000 0,03430246 0,05063296 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03430246 0,05060192 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03430246 0,05057091 ! hormone secretion GO:0046879 38 21 0,000 0,03430246 0,05053994 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03430246 0,05050901 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03430246 0,05047812 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03430246 0,05044727 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03430246 0,05041645 ! axis specification GO:0009798 38 21 0,000 0,03430246 0,05038567 ! ovarian follicle development GO:0001541 35 21 0,000 0,03430246 0,05035493 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03430246 0,05032422 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03430246 0,05029356 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03430246 0,05026293 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03430246 0,05023234 ! cell aging GO:0007569 44 21 0,000 0,03430246 0,05020178 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03430246 0,05017126 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03430246 0,05014078 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03430246 0,05011034 ! vasodilation GO:0042311 39 21 0,000 0,03430246 0,05007993 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03430246 0,05004956 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03430246 0,05001923 ! oogenesis GO:0048477 36 21 0,000 0,03430246 0,04998893 ! DNA modification GO:0006304 34 21 0,000 0,03430246 0,04995867 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03430246 0,04992845 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03430246 0,04989826 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03430246 0,04986811 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03430246 0,049838 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03430246 0,04980792 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03430246 0,04977788 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03430246 0,04974788 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03430246 0,04971791 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03430246 0,04968798 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03430246 0,04965808 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03430246 0,04962822 ! collagen catabolic process GO:0030574 28 21 0,000 0,03430246 0,04959839 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03430246 0,04956861 ! gut development GO:0048565 39 21 0,000 0,03430246 0,04953885 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03590683 0,05182473 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03590683 0,05179366 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03590683 0,05176263 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03590683 0,05173163 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03590683 0,05170067 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03590683 0,05166975 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03590683 0,05163887 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03590683 0,05160802 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03590683 0,05157721 ! regeneration GO:0031099 41 22 0,000 0,03590683 0,05154643 ! keratinization GO:0031424 28 22 0,000 0,03590683 0,0515157 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03590683 0,051485 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03590683 0,05145433 ! sensory perception of taste GO:0050909 28 22 0,000 0,03590683 0,0514237 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03590683 0,05139311 ! vacuolar transport GO:0007034 36 22 0,000 0,03590683 0,05136256 ! lysosome organization GO:0007040 41 22 0,000 0,03590683 0,05133204 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03590683 0,05130156 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03590683 0,05127111 ! fucose metabolic process GO:0006004 39 22 0,000 0,03590683 0,0512407 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03590683 0,05121033 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03590683 0,05117999 ! ureteric bud development GO:0001657 43 22 0,000 0,03590683 0,05114969 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03590683 0,05111942 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03590683 0,05108919 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03590683 0,051059 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,03590683 0,05102884 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03590683 0,05099872 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03590683 0,05096863 ! sarcomere organization GO:0045214 30 22 0,000 0,03590683 0,05093858 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,03590683 0,05090856 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03590683 0,05087858 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03590683 0,05084863 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03590683 0,05081872 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03590683 0,05078884 ! protein stabilization GO:0050821 39 22 0,000 0,03590683 0,050759 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03750858 0,05299215 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03750858 0,05296105 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03750858 0,05292999 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03750858 0,05289896 ! gluconeogenesis GO:0006094 33 23 0,000 0,03750858 0,05286797 ! viral genome replication GO:0019079 41 23 0,000 0,03750858 0,05283702 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03750858 0,0528061 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03750858 0,05277522 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03750858 0,05274438 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03750858 0,05271357 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03750858 0,0526828 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03750858 0,05265206 ! visual behavior GO:0007632 42 23 0,000 0,03750858 0,05262136 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03750858 0,0525907 ! response to ethanol GO:0045471 46 23 0,000 0,03750858 0,05256007 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03750858 0,05252947 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03750858 0,05249891 ! peroxisome organization GO:0007031 37 23 0,000 0,03750858 0,05246839 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03750858 0,0524379 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03750858 0,05240745 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03750858 0,05237704 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03750858 0,05234665 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03750858 0,05231631 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03750858 0,052286 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03750858 0,05225572 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03750858 0,05222548 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03750858 0,05219528 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03750858 0,05216511 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03750858 0,05213497 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03750858 0,05210487 ! fatty acid transport GO:0015908 44 23 0,000 0,03750858 0,0520748 ! platelet activation GO:0030168 37 23 0,000 0,03750858 0,05204477 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03750858 0,05201477 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03750858 0,05198481 ! hormone transport GO:0009914 40 23 0,000 0,03750858 0,05195488 ! cell-cell recognition GO:0009988 25 23 0,000 0,03750858 0,05192499 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03750858 0,05189513 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03750858 0,05186531 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03750858 0,05183552 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03750858 0,05180576 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03750858 0,05177604 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03910772 0,0539525 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03910772 0,05392159 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03910772 0,0538907 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03910772 0,05385986 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03910772 0,05382904 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03910772 0,05379827 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03910772 0,05376752 ! spinal cord development GO:0021510 47 24 0,000 0,03910772 0,05373682 ! vacuole organization GO:0007033 43 24 0,000 0,03910772 0,05370615 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03910772 0,05367551 ! digestive system process GO:0022600 39 24 0,000 0,03910772 0,05364491 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03910772 0,05361434 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03910772 0,05358381 ! regulation of behavior GO:0050795 43 24 0,000 0,03910772 0,05355331 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03910772 0,05352285 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03910772 0,05349242 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03910772 0,05346203 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03910772 0,05343167 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03910772 0,05340134 ! pallium development GO:0021543 49 24 0,000 0,03910772 0,05337105 ! pentose metabolic process GO:0019321 35 24 0,000 0,03910772 0,0533408 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03910772 0,05331058 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03910772 0,05328039 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03910772 0,05325024 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03910772 0,05322012 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03910772 0,05319003 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03910772 0,05315998 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03910772 0,05312997 ! regulation of amine transport GO:0051952 40 24 0,000 0,03910772 0,05309998 ! protein tetramerization GO:0051262 52 24 0,000 0,03910772 0,05307003 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04070426 0,05520543 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,04070426 0,05517433 ! myelination GO:0042552 45 25 0,000 0,04070426 0,05514326 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04070426 0,05511223 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04070426 0,05508124 ! phototransduction GO:0007602 33 25 0,000 0,04070426 0,05505027 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,04070426 0,05501935 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,04070426 0,05498845 ! sperm motility GO:0030317 31 25 0,000 0,04070426 0,0549576 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,04070426 0,05492677 ! receptor metabolic process GO:0043112 46 25 0,000 0,04070426 0,05489599 ! chromosome condensation GO:0030261 45 25 0,000 0,04070426 0,05486523 ! response to starvation GO:0042594 42 25 0,000 0,04070426 0,05483451 ! osteoblast differentiation GO:0001649 60 25 0,000 0,04070426 0,05480383 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,04070426 0,05477318 ! neural crest cell development GO:0014032 54 25 0,000 0,04070426 0,05474256 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04070426 0,05471198 ! negative regulation of cell development GO:0010721 73 25 0,000 0,04070426 0,05468143 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04070426 0,05465091 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04070426 0,05462043 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04070426 0,05458999 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04070426 0,05455958 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04070426 0,0545292 ! immunoglobulin production GO:0002377 55 25 0,000 0,04070426 0,05449885 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04070426 0,05446854 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04070426 0,05443826 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,04070426 0,05440802 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04070426 0,05437781 ! telomere organization GO:0032200 43 25 0,000 0,04070426 0,05434764 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04070426 0,05431749 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04070426 0,05428738 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04229819 0,05638197 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04229819 0,05635075 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04229819 0,05631956 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04229819 0,05628841 ! initiation of viral infection GO:0019059 57 26 0,000 0,04229819 0,0562573 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04229819 0,05622622 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04229819 0,05619517 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04229819 0,05616416 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04229819 0,05613318 ! molting cycle process GO:0022404 50 26 0,000 0,04229819 0,05610223 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04229819 0,05607132 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04229819 0,05604045 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,04229819 0,05600961 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04229819 0,0559788 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04229819 0,05594802 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,04229819 0,05591728 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,04229819 0,05588658 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04229819 0,0558559 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,04229819 0,05582526 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04229819 0,05579466 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04229819 0,05576408 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,04229819 0,05573355 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04229819 0,05570304 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,04229819 0,05567257 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04229819 0,05564213 ! blastocyst development GO:0001824 49 26 0,000 0,04229819 0,05561172 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04229819 0,05558135 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04229819 0,05555101 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04229819 0,05552071 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,04388954 0,05757809 ! neuron fate commitment GO:0048663 48 27 0,000 0,04388954 0,05754672 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04388954 0,05751537 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04388954 0,05748406 ! iron ion transport GO:0006826 59 27 0,000 0,04388954 0,05745279 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04388954 0,05742155 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04388954 0,05739034 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04388954 0,05735917 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04388954 0,05732803 ! fat cell differentiation GO:0045444 50 27 0,000 0,04388954 0,05729692 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04388954 0,05726585 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04388954 0,05723481 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04388954 0,0572038 ! autophagy GO:0006914 41 27 0,000 0,04388954 0,05717283 ! male gonad development GO:0008584 44 27 0,000 0,04388954 0,0571419 ! response to toxin GO:0009636 47 27 0,000 0,04388954 0,05711099 ! primary neural tube formation GO:0014020 51 27 0,000 0,04388954 0,05708012 ! base-excision repair GO:0006284 41 27 0,000 0,04388954 0,05704928 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04388954 0,05701848 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04388954 0,05698771 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04388954 0,05695697 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04388954 0,05692627 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04388954 0,05689559 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04388954 0,05686496 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04388954 0,05683435 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04388954 0,05680378 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04547829 0,05882837 ! circadian rhythm GO:0007623 50 28 0,000 0,04547829 0,05879675 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04547829 0,05876518 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04547829 0,05873363 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04547829 0,05870212 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04547829 0,05867065 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,04547829 0,05863921 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04547829 0,0586078 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04547829 0,05857642 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04547829 0,05854508 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04547829 0,05851377 ! synaptogenesis GO:0007416 42 28 0,000 0,04547829 0,0584825 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,04547829 0,05845126 ! lipid oxidation GO:0034440 43 28 0,000 0,04547829 0,05842005 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04547829 0,05838888 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04547829 0,05835774 ! translational initiation GO:0006413 65 29 0,000 0,04706445 0,06036091 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,04706445 0,06032875 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04706445 0,06029663 ! regulation of pH GO:0006885 43 29 0,000 0,04706445 0,06026454 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04706445 0,06023248 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04706445 0,06020046 ! catechol metabolic process GO:0009712 54 29 0,000 0,04706445 0,06016847 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,04706445 0,06013652 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,04706445 0,0601046 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04706445 0,06007272 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,04706445 0,06004086 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04706445 0,06000905 ! cell fate determination GO:0001709 60 29 0,000 0,04706445 0,05997726 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04706445 0,05994551 ! detection of light stimulus GO:0009583 38 29 0,000 0,04706445 0,05991379 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,04706445 0,05988211 ! tissue homeostasis GO:0001894 48 29 0,000 0,04706445 0,05985046 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,04864803 0,06183157 ! zinc ion transport GO:0006829 45 30 0,000 0,04864803 0,06179893 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04864803 0,06176631 ! cell junction assembly GO:0034329 78 30 0,000 0,04864803 0,06173374 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04864803 0,06170119 ! acute-phase response GO:0006953 49 30 0,000 0,04864803 0,06166869 ! myofibril assembly GO:0030239 47 30 0,000 0,04864803 0,06163621 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04864803 0,06160377 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04864803 0,06157136 ! phospholipid transport GO:0015914 51 30 0,000 0,04864803 0,06153899 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04864803 0,06150666 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04864803 0,06147435 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04864803 0,06144208 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04864803 0,06140985 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04864803 0,06137764 ! eye morphogenesis GO:0048592 60 30 0,000 0,04864803 0,06134547 ! regulation of B cell activation GO:0050864 50 30 0,000 0,04864803 0,06131334 ! response to heat GO:0009408 50 30 0,000 0,04864803 0,06128124 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05022903 0,06323969 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05022903 0,06320662 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05022903 0,06317358 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05022903 0,06314057 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05022903 0,0631076 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05022903 0,06307466 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05022903 0,06304176 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05022903 0,06300889 ! ovulation cycle process GO:0022602 49 31 0,000 0,05022903 0,06297606 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05022903 0,06294326 ! peptide transport GO:0015833 55 31 0,000 0,05022903 0,06291049 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05022903 0,06287776 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05022903 0,06284506 ! mesoderm formation GO:0001707 69 31 0,000 0,05022903 0,0628124 ! natural killer cell activation GO:0030101 45 31 0,000 0,05022903 0,06277977 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05022903 0,06274717 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05022903 0,06271461 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05022903 0,06268208 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05022903 0,06264959 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05022903 0,06261713 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05180746 0,0645514 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05180746 0,06451799 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05180746 0,06448461 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05180746 0,06445127 ! spliceosome assembly GO:0000245 67 32 0,000 0,05180746 0,06441796 ! spindle organization GO:0007051 46 32 0,000 0,05180746 0,06438468 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05180746 0,06435145 ! metanephros development GO:0001656 74 32 0,000 0,05180746 0,06431824 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05180746 0,06428507 ! response to ionizing radiation GO:0010212 65 32 0,000 0,05180746 0,06425193 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05180746 0,06421883 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05180746 0,06418576 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,05180746 0,06415273 ! muscle cell development GO:0055001 49 32 0,000 0,05180746 0,06411973 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05180746 0,06408676 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05180746 0,06405383 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05180746 0,06402093 ! ovulation cycle GO:0042698 51 32 0,000 0,05180746 0,06398806 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05180746 0,06395523 ! BMP signaling pathway GO:0030509 64 32 0,000 0,05180746 0,06392244 ! hindbrain development GO:0030902 61 32 0,000 0,05180746 0,06388967 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,05180746 0,06385694 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05180746 0,06382424 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,05180746 0,06379158 ! gene silencing GO:0016458 65 32 0,000 0,05180746 0,06375895 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,05338332 0,06566475 ! post-embryonic development GO:0009791 69 33 0,000 0,05338332 0,0656312 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,05338332 0,06559768 ! protein targeting to membrane GO:0006612 68 33 0,000 0,05338332 0,0655642 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,05338332 0,06553074 ! ceramide metabolic process GO:0006672 64 33 0,000 0,05338332 0,06549733 ! formation of primary germ layer GO:0001704 72 33 0,000 0,05338332 0,06546394 ! cell fate specification GO:0001708 52 33 0,000 0,05338332 0,0654306 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,05338332 0,06539728 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,05338332 0,065364 ! adult locomotory behavior GO:0008344 59 33 0,000 0,05338332 0,06533075 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,05338332 0,06529754 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,05338332 0,06526436 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,05495661 0,06715368 ! glial cell differentiation GO:0010001 63 34 0,000 0,05495661 0,06711959 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,05495661 0,06708554 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,05495661 0,06705152 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,05495661 0,06701753 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,05495661 0,06698358 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,05495661 0,06694967 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,05495661 0,06691579 ! mismatch repair GO:0006298 46 34 0,000 0,05495661 0,06688194 ! spermatid development GO:0007286 63 34 0,000 0,05495661 0,06684813 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,05495661 0,06681435 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,05495661 0,0667806 ! placenta development GO:0001890 53 34 0,000 0,05495661 0,06674689 ! regulation of muscle development GO:0048634 70 35 0,000 0,05652733 0,06861996 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,05652733 0,06858536 ! negative regulation of secretion GO:0051048 63 35 0,000 0,05652733 0,06855079 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,05652733 0,06851625 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,05652733 0,06848175 ! odontogenesis GO:0042476 66 35 0,000 0,05652733 0,06844729 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,05652733 0,06841286 ! female gonad development GO:0008585 58 35 0,000 0,05652733 0,06837846 ! telencephalon development GO:0021537 68 35 0,000 0,05652733 0,0683441 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,05652733 0,06830977 ! cytokine production GO:0001816 59 35 0,000 0,05652733 0,06827548 ! neural tube formation GO:0001841 67 35 0,000 0,05652733 0,06824123 ! vesicle localization GO:0051648 64 35 0,000 0,05652733 0,068207 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,0580955 0,07006405 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,0580955 0,07002894 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,0580955 0,06999388 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,0580955 0,06995885 ! cell junction organization GO:0034330 86 36 0,000 0,0580955 0,06992385 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,0580955 0,06988889 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,0580955 0,06985396 ! positive regulation of cell development GO:0010720 80 36 0,000 0,0580955 0,06981907 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,0580955 0,06978421 ! regulation of proteolysis GO:0030162 72 36 0,000 0,0580955 0,06974939 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,0580955 0,0697146 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,0580955 0,06967985 ! aerobic respiration GO:0009060 55 36 0,000 0,0580955 0,06964513 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,0580955 0,06961045 ! embryonic organ development GO:0048568 57 36 0,000 0,0580955 0,0695758 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,0580955 0,06954118 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,0580955 0,0695066 ! RNA export from nucleus GO:0006405 56 37 0,000 0,05966111 0,07134425 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05966111 0,07130881 ! meiosis I GO:0007127 65 37 0,000 0,05966111 0,07127341 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,05966111 0,07123803 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05966111 0,0712027 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05966111 0,0711674 ! organic anion transport GO:0015711 68 37 0,000 0,05966111 0,07113213 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05966111 0,0710969 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05966111 0,0710617 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05966111 0,07102654 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05966111 0,07099141 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05966111 0,07095632 ! glycogen metabolic process GO:0005977 61 37 0,000 0,05966111 0,07092127 ! pigment metabolic process GO:0042440 80 37 0,000 0,05966111 0,07088624 ! spermatid differentiation GO:0048515 66 37 0,000 0,05966111 0,07085125 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,06122418 0,07267162 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,06122418 0,07263578 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,06122418 0,07259999 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,06122418 0,07256422 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,06122418 0,07252849 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,06122418 0,0724928 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,06122418 0,07245714 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,06122418 0,07242152 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,06122418 0,07238593 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,06122418 0,07235038 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,06122418 0,07231486 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,06122418 0,07227938 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,06122418 0,07224393 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,06122418 0,07220852 ! glucan metabolic process GO:0044042 62 38 0,000 0,06122418 0,07217314 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,06278469 0,07397648 ! learning GO:0007612 77 39 0,000 0,06278469 0,07394027 ! ear morphogenesis GO:0042471 60 39 0,000 0,06278469 0,0739041 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,06278469 0,07386796 ! segmentation GO:0035282 67 39 0,000 0,06278469 0,07383185 ! ion transmembrane transport GO:0034220 66 39 0,000 0,06278469 0,07379579 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,06278469 0,07375975 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,06278469 0,07372376 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,06278469 0,07368779 ! RNA modification GO:0009451 57 39 0,000 0,06278469 0,07365186 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,06278469 0,07361597 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,06434267 0,07540597 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,06434267 0,07536926 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,06434267 0,07533258 ! feeding behavior GO:0007631 59 40 0,000 0,06434267 0,07529594 ! negative regulation of binding GO:0051100 72 40 0,000 0,06434267 0,07525934 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,06434267 0,07522277 ! mesenchymal cell development GO:0014031 87 40 0,000 0,06434267 0,07518624 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,06434267 0,07514974 ! maintenance of protein location GO:0045185 91 40 0,000 0,06434267 0,07511328 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06589811 0,07689178 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06589811 0,0768545 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06589811 0,07681727 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06589811 0,07678007 ! gliogenesis GO:0042063 88 41 0,000 0,06589811 0,07674291 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06589811 0,07670578 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06589811 0,07666869 ! T cell differentiation GO:0030217 81 41 0,000 0,06589811 0,07663163 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,06589811 0,07659461 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06589811 0,07655763 ! female gamete generation GO:0007292 61 41 0,000 0,06589811 0,07652068 ! polyol metabolic process GO:0019751 66 41 0,000 0,06589811 0,07648376 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06589811 0,07644689 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06745101 0,07821066 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06745101 0,07817299 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,06745101 0,07813535 ! regulation of tube size GO:0035150 71 42 0,000 0,06745101 0,07809775 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06745101 0,07806019 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,06745101 0,07802266 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,06745101 0,07798516 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,06745101 0,07794771 ! neuron migration GO:0001764 79 42 0,000 0,06745101 0,07791029 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06745101 0,0778729 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,06745101 0,07783555 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,06900138 0,07958644 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,06900138 0,07954831 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,06900138 0,07951021 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,06900138 0,07947215 ! glucose transport GO:0015758 65 43 0,000 0,06900138 0,07943413 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,06900138 0,07939614 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,06900138 0,07935818 ! neural tube development GO:0021915 77 43 0,000 0,06900138 0,07932027 ! striated muscle contraction GO:0006941 77 43 0,000 0,06900138 0,07928239 ! phagocytosis GO:0006909 90 43 0,000 0,06900138 0,07924455 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,06900138 0,07920674 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,07054923 0,08094489 ! hexose transport GO:0008645 67 44 0,000 0,07054923 0,08090631 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,07054923 0,08086777 ! male sex differentiation GO:0046661 76 44 0,000 0,07054923 0,08082926 ! double-strand break repair GO:0006302 81 44 0,000 0,07054923 0,08079079 ! biopolymer methylation GO:0043414 84 44 0,000 0,07054923 0,08075235 ! B cell differentiation GO:0030183 107 44 0,000 0,07054923 0,08071395 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,07054923 0,08067559 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,07054923 0,08063726 ! developmental growth GO:0048589 82 44 0,000 0,07054923 0,08059897 ! maintenance of location in cell GO:0051651 97 44 0,000 0,07054923 0,08056072 ! glycolysis GO:0006096 65 45 0,000 0,07209455 0,08228629 ! leukocyte migration GO:0050900 68 45 0,000 0,07209455 0,08224727 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,07209455 0,08220829 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,07209455 0,08216935 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,07209455 0,08213044 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,07209455 0,08209157 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,07209455 0,08205274 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,07209455 0,08201394 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,07209455 0,08197518 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,07209455 0,08193646 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,07363736 0,08365037 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,07363736 0,08361089 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,07363736 0,08357145 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,07363736 0,08353205 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,07363736 0,08349269 ! pigmentation GO:0043473 100 46 0,000 0,07363736 0,08345336 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,07363736 0,08341407 ! positive regulation of defense response GO:0031349 76 47 0,000 0,07517765 0,08511879 ! response to calcium ion GO:0051592 81 47 0,000 0,07517765 0,08507875 ! endosome transport GO:0016197 108 47 0,000 0,07517765 0,08503875 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,07517765 0,08499879 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,07517765 0,08495887 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,07517765 0,08491898 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,07517765 0,08487913 ! JNK cascade GO:0007254 91 47 0,000 0,07517765 0,08483932 ! methylation GO:0032259 90 47 0,000 0,07517765 0,08479954 ! mitochondrial transport GO:0006839 82 48 0,000 0,07671543 0,08649359 ! Notch signaling pathway GO:0007219 96 48 0,000 0,07671543 0,08645308 ! cellular component disassembly GO:0022411 86 48 0,000 0,07671543 0,08641261 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,07671543 0,08637217 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,07671543 0,08633177 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,07671543 0,08629141 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,07671543 0,08625109 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,07671543 0,0862108 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07825071 0,08789505 ! regulation of action potential GO:0001508 95 49 0,000 0,07825071 0,08785404 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,07825071 0,08781306 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07825071 0,08777212 ! regulation of ion transport GO:0043269 77 49 0,000 0,07825071 0,08773122 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,07825071 0,08769036 ! peptide metabolic process GO:0006518 76 49 0,000 0,07825071 0,08764954 ! response to temperature stimulus GO:0009266 76 49 0,000 0,07825071 0,08760875 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07825071 0,087568 ! endocrine system development GO:0035270 104 49 0,000 0,07825071 0,08752729 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,07825071 0,08748662 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07825071 0,08744599 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07825071 0,08740539 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07978348 0,08907613 ! neuromuscular process GO:0050905 99 50 0,000 0,07978348 0,08903482 ! regulation of ossification GO:0030278 117 50 0,000 0,07978348 0,08899354 ! inner ear development GO:0048839 79 50 0,000 0,07978348 0,0889523 ! histone modification GO:0016570 91 50 0,000 0,07978348 0,0889111 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,07978348 0,08886994 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,07978348 0,08882881 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,07978348 0,08878772 ! positive regulation of binding GO:0051099 78 51 0,000 0,08131376 0,09044887 ! viral infectious cycle GO:0019058 99 51 0,000 0,08131376 0,09040707 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,08131376 0,09036531 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,08131376 0,09032359 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,08131376 0,09028191 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,08131376 0,09024027 ! chromatin remodeling GO:0006338 109 51 0,000 0,08131376 0,09019867 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,08131376 0,0901571 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,08131376 0,09011557 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,08131376 0,09007408 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,08131376 0,09003263 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,08284154 0,09168204 ! positive regulation of growth GO:0045927 90 52 0,000 0,08284154 0,09163989 ! covalent chromatin modification GO:0016569 101 52 0,000 0,08284154 0,09159777 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,08284154 0,0915557 ! amino acid activation GO:0043038 92 52 0,000 0,08284154 0,09151366 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,08284154 0,09147166 ! synapse organization GO:0050808 85 52 0,000 0,08284154 0,0914297 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,08436684 0,09307043 ! RNA catabolic process GO:0006401 93 53 0,000 0,08436684 0,09302778 ! regulation of translational initiation GO:0006446 82 53 0,000 0,08436684 0,09298516 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,08436684 0,09294259 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,08436684 0,09290005 ! cell maturation GO:0048469 100 53 0,000 0,08436684 0,09285755 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,08588964 0,09449039 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,08588964 0,0944472 ! cell recognition GO:0008037 85 54 0,000 0,08588964 0,09440406 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,08588964 0,09436095 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,08588964 0,09431788 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,08588964 0,09427485 ! chloride transport GO:0006821 90 55 0,000 0,08740997 0,09589985 ! glucose catabolic process GO:0006007 82 55 0,000 0,08740997 0,09585614 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,08740997 0,09581247 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08740997 0,09576884 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08740997 0,09572525 ! aging GO:0007568 103 55 0,000 0,08740997 0,0956817 ! gastrulation GO:0007369 112 55 0,000 0,08740997 0,09563819 ! heart morphogenesis GO:0003007 97 55 0,000 0,08740997 0,09559472 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,08740997 0,09555129 ! RNA elongation GO:0006354 79 55 0,000 0,08740997 0,09550789 ! nuclear export GO:0051168 97 55 0,000 0,08740997 0,09546454 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,08740997 0,09542122 ! sensory perception of smell GO:0007608 80 56 0,000 0,08892781 0,09703416 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,08892781 0,09699017 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,08892781 0,09694622 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,08892781 0,09690232 ! regulation of DNA replication GO:0006275 101 56 0,000 0,08892781 0,09685845 ! proton transport GO:0015992 94 56 0,000 0,08892781 0,09681462 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,09044319 0,09841986 ! muscle fiber development GO:0048747 112 57 0,000 0,09044319 0,09837536 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,09044319 0,09833091 ! maintenance of location GO:0051235 118 57 0,000 0,09044319 0,0982865 ! hydrogen transport GO:0006818 97 58 0,000 0,09195609 0,09988548 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,09195609 0,09984041 ! regulation of endocytosis GO:0030100 91 58 0,000 0,09195609 0,09979538 ! adult behavior GO:0030534 99 58 0,000 0,09195609 0,09975038 ! positive regulation of secretion GO:0051047 95 59 0,000 0,09346652 0,10134315 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,09346652 0,1012975 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,09346652 0,10125189 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,09346652 0,10120633 ! DNA catabolic process GO:0006308 86 59 0,000 0,09346652 0,1011608 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,09346652 0,10111531 ! establishment of organelle localization GO:0051656 109 59 0,000 0,09346652 0,10106987 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,0949745 0,10265438 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,0949745 0,10260828 ! regulation of heart contraction GO:0008016 110 60 0,000 0,0949745 0,10256223 ! camera-type eye development GO:0043010 116 60 0,000 0,0949745 0,10251621 ! kidney development GO:0001822 122 60 0,000 0,0949745 0,10247024 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,09648001 0,10404792 ! mesoderm development GO:0007498 119 61 0,000 0,09648001 0,1040013 ! tRNA processing GO:0008033 89 61 0,000 0,09648001 0,10395473 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,09648001 0,1039082 ! ear development GO:0043583 103 62 0,000 0,09798307 0,10547977 ! viral reproductive process GO:0022415 126 62 0,000 0,09798307 0,10543259 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09798307 0,10538546 ! gonad development GO:0008406 98 62 0,000 0,09798307 0,10533837 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,09798307 0,10529132 ! regulation of mitosis GO:0007088 105 63 0,000 0,09948368 0,10685614 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,09948368 0,10680845 ! detection of external stimulus GO:0009581 91 63 0,000 0,09948368 0,10676081 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,09948368 0,10671322 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,09948368 0,10666566 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,10098185 0,10822375 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,10098185 0,10817557 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,10098185 0,10812743 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,10247757 0,10968017 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,10247757 0,10963141 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,10247757 0,10958268 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,10247757 0,109534 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,10247757 0,10948536 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,10397085 0,11103146 ! actin filament organization GO:0007015 148 66 0,000 0,10397085 0,1109822 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,10397085 0,11093298 ! extracellular matrix organization GO:0030198 133 66 0,000 0,10397085 0,11088381 ! secondary metabolic process GO:0019748 116 66 0,000 0,10397085 0,11083468 ! developmental maturation GO:0021700 116 66 0,000 0,10397085 0,11078559 ! cell projection assembly GO:0030031 120 66 0,000 0,10397085 0,11073655 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,1054617 0,11227471 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,1054617 0,11222505 ! activation of MAPK activity GO:0000187 115 67 0,000 0,1054617 0,11217544 ! lung development GO:0030324 144 67 0,000 0,1054617 0,11212587 ! chromosome segregation GO:0007059 113 67 0,000 0,1054617 0,11207635 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,1054617 0,11202686 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,1054617 0,11197743 ! hexose catabolic process GO:0019320 104 67 0,000 0,1054617 0,11192803 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,1054617 0,11187868 ! amino acid transport GO:0006865 125 68 0,000 0,10695012 0,11340766 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,10695012 0,1133577 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,10695012 0,11330778 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,10695012 0,11325791 ! viral reproduction GO:0016032 134 68 0,000 0,10695012 0,11320809 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,10695012 0,1131583 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,1084361 0,11468012 ! negative regulation of cell size GO:0045792 134 69 0,000 0,1084361 0,11462973 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,1084361 0,11457939 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,1084361 0,11452909 ! urogenital system development GO:0001655 137 69 0,000 0,1084361 0,11447884 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,1084361 0,11442863 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,1084361 0,11437846 ! antigen processing and presentation GO:0019882 104 69 0,000 0,1084361 0,11432834 ! appendage morphogenesis GO:0035107 135 70 0,000 0,10991967 0,11584176 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,10991967 0,11579104 ! amine catabolic process GO:0009310 117 71 0,000 0,11140082 0,11729994 ! reproductive structure development GO:0048608 113 71 0,000 0,11140082 0,11724863 ! appendage development GO:0048736 136 71 0,000 0,11140082 0,11719736 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,11140082 0,11714614 ! regulation of immune effector process GO:0002697 137 71 0,000 0,11140082 0,11709496 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,11287955 0,11859746 ! carbohydrate transport GO:0008643 110 72 0,000 0,11287955 0,1185457 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,11287955 0,11849398 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,11287955 0,1184423 ! respiratory system development GO:0060541 153 72 0,000 0,11287955 0,11839067 ! learning or memory GO:0007611 147 73 0,000 0,11435587 0,11988681 ! regulation of blood pressure GO:0008217 125 73 0,000 0,11435587 0,11983459 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,11435587 0,11978242 ! axon guidance GO:0007411 139 73 0,000 0,11435587 0,1197303 ! fertilization GO:0009566 90 73 0,000 0,11435587 0,11967822 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,11582978 0,12116802 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,11582978 0,12111536 ! neurotransmitter transport GO:0006836 123 74 0,000 0,11582978 0,12106275 ! meiosis GO:0007126 121 74 0,000 0,11582978 0,12101018 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,11582978 0,12095766 ! eye development GO:0001654 143 74 0,000 0,11582978 0,12090518 ! organelle localization GO:0051640 136 74 0,000 0,11582978 0,12085275 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,11730129 0,12233502 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,11730129 0,12228202 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,11730129 0,12222906 ! meiotic cell cycle GO:0051321 122 75 0,000 0,11730129 0,12217615 ! rhythmic process GO:0048511 128 75 0,000 0,11730129 0,12212328 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,11730129 0,12207046 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,1187704 0,12354586 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,1187704 0,12349247 ! defense response to bacterium GO:0042742 89 76 0,000 0,1187704 0,12343912 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,1187704 0,12338583 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,1187704 0,12333257 ! regulation of catabolic process GO:0009894 161 76 0,000 0,1187704 0,12327937 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,12023711 0,12474794 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,12023711 0,12469417 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,12023711 0,12464045 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,12170143 0,12610406 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,12170143 0,12604978 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,12170143 0,12599554 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,12316336 0,12745421 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,12316336 0,12739941 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,12316336 0,12734467 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,12316336 0,12728996 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,12316336 0,12723531 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,1246229 0,12868786 ! response to metal ion GO:0010038 140 80 0,000 0,1246229 0,12863265 ! muscle cell differentiation GO:0042692 159 80 0,000 0,1246229 0,12857749 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,1246229 0,12852238 ! protein import into nucleus GO:0006606 158 80 0,000 0,1246229 0,12846731 ! inorganic anion transport GO:0015698 138 80 0,000 0,1246229 0,12841229 ! T cell activation GO:0042110 168 81 0,000 0,12608007 0,12985815 ! digestion GO:0007586 112 81 0,000 0,12608007 0,12980259 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,12608007 0,12974707 ! nuclear import GO:0051170 161 81 0,000 0,12608007 0,1296916 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,12608007 0,12963617 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,12753485 0,13107598 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,12753485 0,13102001 ! response to drug GO:0042493 143 82 0,000 0,12753485 0,13096409 ! response to nutrient GO:0007584 125 82 0,000 0,12753485 0,13090822 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,12753485 0,13085239 ! regulation of lyase activity GO:0051339 160 83 0,000 0,12898727 0,13228618 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,13043731 0,13371631 ! negative regulation of transport GO:0051051 153 84 0,000 0,13043731 0,13365936 ! negative regulation of growth GO:0045926 155 84 0,000 0,13043731 0,13360246 ! regulation of ligase activity GO:0051340 142 84 0,000 0,13043731 0,13354561 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,13043731 0,1334888 ! response to unfolded protein GO:0006986 131 85 0,000 0,13188499 0,13491296 ! nucleosome assembly GO:0006334 122 85 0,000 0,13188499 0,13485563 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,13188499 0,13479834 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,13188499 0,1347411 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,13333031 0,1361599 ! response to inorganic substance GO:0010035 153 86 0,000 0,13333031 0,13610213 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,13333031 0,13604441 ! chromatin assembly GO:0031497 124 86 0,000 0,13333031 0,13598674 ! tube morphogenesis GO:0035239 176 86 0,000 0,13333031 0,13592912 ! mitochondrion organization GO:0007005 148 86 0,000 0,13333031 0,13587155 ! alcohol catabolic process GO:0046164 130 86 0,000 0,13333031 0,13581402 ! amine transport GO:0015837 155 86 0,000 0,13333031 0,13575655 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,13477327 0,13716772 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,13477327 0,13710972 ! protein localization in nucleus GO:0034504 176 87 0,000 0,13477327 0,13705177 ! regulation of protein transport GO:0051223 154 87 0,000 0,13477327 0,13699387 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,13621387 0,13839974 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,13621387 0,13834131 ! regulation of DNA binding GO:0051101 155 88 0,000 0,13621387 0,13828294 ! regulation of neurological system process GO:0031644 148 88 0,000 0,13621387 0,13822462 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,13621387 0,13816635 ! cellular defense response GO:0006968 114 89 0,000 0,13765212 0,13956638 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,13908803 0,14096285 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,13908803 0,1409035 ! sex differentiation GO:0007548 145 90 0,000 0,13908803 0,14084419 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,13908803 0,14078494 ! sterol metabolic process GO:0016125 152 91 0,000 0,14052159 0,14217618 ! response to protein stimulus GO:0051789 149 91 0,000 0,14052159 0,14211642 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,14052159 0,1420567 ! nucleosome organization GO:0034728 138 92 0,000 0,14195282 0,14344329 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,14195282 0,14338307 ! vitamin metabolic process GO:0006766 139 92 0,000 0,14195282 0,1433229 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,14338171 0,14470486 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,14338171 0,14464419 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,14338171 0,14458356 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,14480826 0,1459609 ! female pregnancy GO:0007565 164 94 0,000 0,14480826 0,14589978 ! transcription initiation GO:0006352 153 94 0,000 0,14480826 0,14583871 ! regulation of T cell activation GO:0050863 158 94 0,000 0,14480826 0,14577769 ! forebrain development GO:0030900 188 95 0,000 0,14623249 0,14714988 ! leukocyte differentiation GO:0002521 202 96 0,000 0,14765439 0,14851859 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,14765439 0,14845653 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,14765439 0,14839451 ! detection of stimulus GO:0051606 151 96 0,000 0,14765439 0,14833255 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,14907397 0,14969615 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,14907397 0,1496337 ! protein ubiquitination GO:0016567 217 97 0,000 0,14907397 0,1495713 ! hormone metabolic process GO:0042445 157 97 0,000 0,14907397 0,14950895 ! regulation of protein localization GO:0032880 176 97 0,000 0,14907397 0,14944666 ! response to virus GO:0009615 160 98 0,000 0,15049124 0,15080463 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,15049124 0,15074185 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,15049124 0,15067912 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,15190619 0,15203257 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,15190619 0,15196935 ! cell cycle arrest GO:0007050 213 100 0,000 0,15331883 0,15331883