pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/753-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 1,912E-11 4,671E-08 ! myoblast cell fate commitment GO:0048625 18 6 2,000 1,946E-07 2,377E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 5,431E-07 4,423E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 1,593E-06 9,728E-04 ! mesenchymal cell development GO:0014031 94 41 3,000 1,939E-06 9,476E-04 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of hormone metabolic process GO:0032350 28 12 2,000 2,12E-06 8,634E-04 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 4,365E-06 1,523E-03 ! myoblast differentiation GO:0045445 50 17 2,000 6,503E-06 1,986E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 9,238E-06 2,508E-03 ! pancreas development GO:0031016 40 20 2,000 1,085E-05 2,651E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,264E-05 2,807E-03 ! ureteric bud development GO:0001657 50 22 2,000 1,461E-05 2,975E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,915E-05 3,598E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,915E-05 3,341E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 2,172E-05 3,538E-03 ! fat cell differentiation GO:0045444 57 28 2,000 3,08E-05 4,702E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 3,43E-05 4,929E-03 ! cytokine secretion GO:0050663 15 5 1,000 4,613E-05 6,26E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,613E-05 5,931E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 4,613E-05 5,634E-03 ! enteric nervous system development GO:0048484 8 5 1,000 4,613E-05 5,366E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,613E-05 5,122E-03 ! metanephros development GO:0001656 81 32 2,000 4,634E-05 4,922E-03 ! regulation of ARF GTPase activity GO:0032312 73 34 2,000 5,573E-05 5,673E-03 ! skeletal muscle tissue development GO:0007519 223 100 3,000 6,817E-05 6,662E-03 GO:0060538|skeletal muscle organ development, ! androgen receptor signaling pathway GO:0030521 81 37 2,000 7,202E-05 6,768E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 8,445E-05 7,641E-03 GO:0042593|glucose homeostasis, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 9,659E-05 8,428E-03 ! vesicle fusion GO:0006906 20 7 1,000 9,659E-05 8,137E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 9,659E-05 7,866E-03 ! regulation of hormone secretion GO:0046883 69 41 2,000 9,82E-05 7,739E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,286E-04 9,819E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,286E-04 9,521E-03 ! mast cell activation GO:0045576 14 8 1,000 1,286E-04 9,241E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,286E-04 8,977E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 1,286E-04 8,728E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,286E-04 8,492E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,286E-04 8,268E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,299E-04 8,137E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,651E-04 0,01008491 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,651E-04 9,839E-03 ! S phase GO:0051320 10 9 1,000 1,651E-04 9,605E-03 GO:0000084|S phase of mitotic cell cycle, ! protein homooligomerization GO:0051260 84 49 2,000 1,676E-04 9,523E-03 ! regulation of ARF protein signal transduction GO:0032012 115 50 2,000 1,78E-04 9,885E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,061E-04 0,01118971 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 2,239E-04 0,0118918 ! skeletal muscle fiber development GO:0048741 130 56 2,000 2,495E-04 0,01296664 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,516E-04 0,01280353 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 2,516E-04 0,01254223 ! muscle fiber development GO:0048747 131 57 2,000 2,629E-04 0,01284579 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 3,015E-04 0,01444014 ! autonomic nervous system development GO:0048483 24 12 1,000 3,015E-04 0,01416245 ! localization within membrane GO:0051668 26 12 1,000 3,015E-04 0,01389523 ! kidney development GO:0001822 133 60 2,000 3,06E-04 0,01384573 ! positive regulation of secretion GO:0051047 110 61 2,000 3,214E-04 0,01427491 ! organelle fusion GO:0048284 36 13 1,000 3,558E-04 0,01552008 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,558E-04 0,0152478 ! gland morphogenesis GO:0022612 31 13 1,000 3,558E-04 0,0149849 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 4,055E-04 0,01678849 ! lipid localization GO:0010876 32 14 1,000 4,145E-04 0,01687591 GO:0019915|lipid storage, ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 4,145E-04 0,01659925 GO:0060675|ureteric bud morphogenesis, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 4,145E-04 0,01633152 ! urogenital system development GO:0001655 149 69 2,000 4,621E-04 0,01791815 ! regulation of vasodilation GO:0042312 27 15 1,000 4,776E-04 0,01822956 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 4,776E-04 0,0179491 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 5,025E-04 0,01859999 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 5,235E-04 0,01908931 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 5,45E-04 0,01958073 ! cell-matrix adhesion GO:0007160 181 76 2,000 6,133E-04 0,02171375 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 6,168E-04 0,02152719 ! protein oligomerization GO:0051259 149 79 2,000 6,867E-04 0,02362696 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 6,93E-04 0,02351232 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 6,93E-04 0,02319023 ! neural crest cell migration GO:0001755 41 18 1,000 6,93E-04 0,02287685 ! muscle cell differentiation GO:0042692 178 81 2,000 7,386E-04 0,02405725 ! regulation of peptidase activity GO:0052547 150 82 2,000 7,654E-04 0,02460402 ! cell-substrate adhesion GO:0031589 189 82 2,000 7,654E-04 0,02428449 ! neuron maturation GO:0042551 46 19 1,000 7,734E-04 0,02422302 ! protein secretion GO:0009306 45 20 1,000 8,581E-04 0,02653649 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 8,581E-04 0,02620478 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 8,581E-04 0,02588127 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 8,581E-04 0,02556564 ! lipid phosphorylation GO:0046834 43 21 1,000 9,471E-04 0,02787716 ! regulation of vasoconstriction GO:0019229 40 21 1,000 9,471E-04 0,02754528 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 9,471E-04 0,02722122 ! tube morphogenesis GO:0035239 194 89 2,000 9,709E-04 0,02758074 ! inactivation of MAPK activity GO:0000188 45 22 1,000 1,04E-03 0,02921396 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,04E-03 0,02888198 ! gut development GO:0048565 44 22 1,000 1,04E-03 0,02855746 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,24E-03 0,03364692 ! membrane depolarization GO:0051899 45 24 1,000 1,24E-03 0,03327718 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,24E-03 0,03291547 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 1,282E-03 0,03368497 ! vasculogenesis GO:0001570 49 25 1,000 1,345E-03 0,03496736 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,345E-03 0,03459929 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,456E-03 0,03704012 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,456E-03 0,03665827 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 1,456E-03 0,0362842 ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,456E-03 0,0359177 ! neural crest cell development GO:0014032 59 26 1,000 1,456E-03 0,03555852 GO:0014033|neural crest cell differentiation, ! regulation of blood coagulation GO:0030193 46 26 1,000 1,456E-03 0,03520645 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,456E-03 0,03486129 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,57E-03 0,03723241 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 1,57E-03 0,0368744 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,688E-03 0,03927758 ! vesicle docking GO:0048278 55 28 1,000 1,688E-03 0,03890703 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 1,688E-03 0,03854342 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 1,937E-03 0,04382178 ! regulation of coagulation GO:0050818 52 30 1,000 1,937E-03 0,04341974 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 2,068E-03 0,04592784 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 2,203E-03 0,04848036 ! myeloid leukocyte activation GO:0002274 53 32 1,000 2,203E-03 0,0480475 ! cholesterol homeostasis GO:0042632 60 33 1,000 2,342E-03 0,05062372 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 2,342E-03 0,05017966 ! inner ear morphogenesis GO:0042472 51 34 1,000 2,484E-03 0,05277828 ! cholesterol transport GO:0030301 62 34 1,000 2,484E-03 0,05232329 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,484E-03 0,05187608 ! membrane docking GO:0022406 69 35 1,000 2,631E-03 0,05447745 ! sterol transport GO:0015918 63 35 1,000 2,631E-03 0,05401966 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,631E-03 0,0535695 ! cytokine production GO:0001816 68 36 1,000 2,782E-03 0,05617315 ! tissue remodeling GO:0048771 78 37 1,000 2,937E-03 0,05881388 ! regulation of microtubule-based process GO:0032886 86 37 1,000 2,937E-03 0,05833572 ! neutral lipid metabolic process GO:0006638 54 38 1,000 3,096E-03 0,06099455 GO:0006639|acylglycerol metabolic process, ! cellular response to insulin stimulus GO:0032869 85 38 1,000 3,096E-03 0,0605066 ! lipid homeostasis GO:0055088 75 40 1,000 3,425E-03 0,06641492 ! glycerol ether metabolic process GO:0006662 57 40 1,000 3,425E-03 0,06589197 ! mammary gland development GO:0030879 93 40 1,000 3,425E-03 0,06537719 ! mismatch repair GO:0006298 58 40 1,000 3,425E-03 0,06487039 ! establishment or maintenance of cell polarity GO:0007163 96 41 1,000 3,596E-03 0,06757785 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 3,596E-03 0,06706199 ! ear morphogenesis GO:0042471 64 42 1,000 3,771E-03 0,06978393 ! organic ether metabolic process GO:0018904 59 42 1,000 3,771E-03 0,06925924 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 3,771E-03 0,06874238 ! epithelial cell differentiation GO:0030855 83 43 1,000 3,949E-03 0,07146158 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 4,317E-03 0,07755326 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 4,317E-03 0,07698718 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 4,507E-03 0,07979171 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 4,507E-03 0,07921767 ! positive regulation of protein transport GO:0051222 80 46 1,000 4,507E-03 0,07865183 ! regulation of JNK cascade GO:0046328 104 47 1,000 4,701E-03 0,0814509 ! response to insulin stimulus GO:0032868 98 47 1,000 4,701E-03 0,08087731 ! positive regulation of cell cycle GO:0045787 96 48 1,000 4,899E-03 0,08368648 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 4,899E-03 0,08310533 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 4,899E-03 0,08253219 ! regulation of ossification GO:0030278 123 50 1,000 5,305E-03 0,08876701 ! Notch signaling pathway GO:0007219 111 52 1,000 5,726E-03 0,09516584 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 5,726E-03 0,09452283 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 5,726E-03 0,09388844 ! inner ear development GO:0048839 89 53 1,000 5,943E-03 0,0967846 ! vesicle organization GO:0016050 127 53 1,000 5,943E-03 0,09614364 ! activation of phospholipase C activity GO:0007202 110 54 1,000 6,163E-03 0,0990462 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 6,163E-03 0,09839884 ! membrane fusion GO:0006944 122 54 1,000 6,163E-03 0,09775989 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 6,386E-03 0,10065379 ! cell maturation GO:0048469 107 55 1,000 6,386E-03 0,10000857 ! regulation of protein polymerization GO:0032271 117 55 1,000 6,386E-03 0,09937158 ! response to UV GO:0009411 120 55 1,000 6,386E-03 0,09874264 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 6,844E-03 0,10516195 ! regulation of bone remodeling GO:0046850 143 57 1,000 6,844E-03 0,10450469 ! regulation of phospholipase activity GO:0010517 113 57 1,000 6,844E-03 0,10385559 ! regulation of intracellular transport GO:0032386 108 57 1,000 6,844E-03 0,10321451 ! positive regulation of cell migration GO:0030335 137 58 1,000 7,079E-03 0,10609673 ! regulation of tissue remodeling GO:0034103 146 58 1,000 7,079E-03 0,1054498 ! positive regulation of organelle organization GO:0010638 108 58 1,000 7,079E-03 0,10481071 ! positive regulation of lipase activity GO:0060193 115 58 1,000 7,079E-03 0,10417932 ! lipid modification GO:0030258 112 60 1,000 7,559E-03 0,11057619 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 8,053E-03 0,11710502 ! regulation of protein complex assembly GO:0043254 132 63 1,000 8,306E-03 0,12006134 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 8,561E-03 0,1230336 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 8,561E-03 0,1223141 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 8,561E-03 0,12160297 ! positive regulation of cell motion GO:0051272 157 65 1,000 8,821E-03 0,12456439 ! ear development GO:0043583 114 66 1,000 9,084E-03 0,12754087 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 9,084E-03 0,12681207 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 9,35E-03 0,12979028 GO:0035113|embryonic appendage morphogenesis, ! regulation of cellular response to stress GO:0080135 142 68 1,000 9,62E-03 0,13278267 ! regulation of lipase activity GO:0060191 137 68 1,000 9,62E-03 0,1320367 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 9,894E-03 0,13503019 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 9,894E-03 0,13428003 ! developmental maturation GO:0021700 128 69 1,000 9,894E-03 0,13353815 ! negative regulation of kinase activity GO:0033673 145 70 1,000 0,01017055 0,13652014 ! appendage morphogenesis GO:0035107 150 72 1,000 0,01073442 0,14330163 GO:0035108|limb morphogenesis, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01078542 0,14319991 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01078542 0,14242586 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01078542 0,14166013 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01078542 0,14090259 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01078542 0,14015311 ! neuron fate determination GO:0048664 7 5 0,000 0,01078542 0,13941156 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01078542 0,13867781 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01078542 0,13795175 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01078542 0,13723325 ! polyol transport GO:0015791 12 5 0,000 0,01078542 0,1365222 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01078542 0,13581848 ! response to superoxide GO:0000303 10 5 0,000 0,01078542 0,13512197 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01078542 0,13443257 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01078542 0,13375017 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01078542 0,13307467 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01078542 0,13240595 ! female meiosis GO:0007143 10 5 0,000 0,01078542 0,13174392 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01078542 0,13108848 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01078542 0,13043953 ! hypothalamus development GO:0021854 9 5 0,000 0,01078542 0,12979697 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01078542 0,12916071 ! cobalt ion transport GO:0006824 11 5 0,000 0,01078542 0,12853065 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01078542 0,12790672 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01078542 0,12728881 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01078542 0,12667685 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01078542 0,12607074 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01078542 0,1254704 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01078542 0,12487575 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01078542 0,12428672 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01078542 0,12370321 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01078542 0,12312516 ! transposition GO:0032196 9 5 0,000 0,01078542 0,12255248 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01078542 0,12198511 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01078542 0,12142297 ! negative chemotaxis GO:0050919 16 5 0,000 0,01078542 0,12086598 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01078542 0,12031408 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01078542 0,1197672 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01078542 0,11922527 ! behavioral response to pain GO:0048266 10 5 0,000 0,01078542 0,11868822 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01078542 0,11815598 ! Notch receptor processing GO:0007220 11 5 0,000 0,01078542 0,1176285 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01078542 0,11710571 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01078542 0,11658754 ! micturition GO:0060073 9 5 0,000 0,01078542 0,11607394 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01078542 0,11556484 ! copulation GO:0007620 9 5 0,000 0,01078542 0,11506019 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01078542 0,11455993 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01078542 0,114064 ! bioluminescence GO:0008218 9 5 0,000 0,01078542 0,11357235 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01078542 0,11308491 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01078542 0,11260164 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01078542 0,11212249 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01078542 0,11164739 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01078542 0,1111763 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01078542 0,11070918 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01078542 0,11024596 ! grooming behavior GO:0007625 6 5 0,000 0,01078542 0,1097866 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01078542 0,10933105 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01078542 0,10887927 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01078542 0,10843121 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01078542 0,10798682 ! response to protozoan GO:0001562 13 5 0,000 0,01078542 0,10754606 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01078542 0,10710888 ! lymph vessel development GO:0001945 10 5 0,000 0,01078542 0,10667524 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01078542 0,1062451 ! endochondral ossification GO:0001958 17 5 0,000 0,01078542 0,10581841 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01078542 0,10539514 ! single strand break repair GO:0000012 8 5 0,000 0,01078542 0,10497524 ! parathyroid gland development GO:0060017 14 5 0,000 0,01078542 0,10455867 ! anagen GO:0042640 7 5 0,000 0,01078542 0,10414539 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01078542 0,10373537 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01078542 0,10332857 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01078542 0,10292494 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01078542 0,10252445 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01078542 0,10212707 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01078542 0,10173276 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01078542 0,10134148 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01078542 0,1009532 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01078542 0,10056788 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01078542 0,10018549 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01078542 0,099806 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01078542 0,09942937 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01078542 0,09905558 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01078542 0,09868459 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01078542 0,09831636 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01078542 0,09795087 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01078542 0,09758809 ! microvillus organization GO:0032528 8 5 0,000 0,01078542 0,09722799 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01078542 0,09687053 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01078542 0,09651569 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01078542 0,09616345 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01078542 0,09581376 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01078542 0,09546661 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01078542 0,09512196 ! polyol catabolic process GO:0046174 9 5 0,000 0,01078542 0,0947798 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01078542 0,09444009 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01078542 0,0941028 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01078542 0,09376792 ! muscle cell migration GO:0014812 8 5 0,000 0,01078542 0,0934354 ! mitochondrial fission GO:0000266 8 5 0,000 0,01078542 0,09310524 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01078542 0,09277741 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01078542 0,09245187 ! mRNA transcription GO:0009299 10 5 0,000 0,01078542 0,09212862 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01078542 0,09180761 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01078542 0,09148883 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01078542 0,09117226 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01078542 0,09085788 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01078542 0,09054565 ! monocyte activation GO:0042117 10 5 0,000 0,01078542 0,09023556 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01078542 0,08992759 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01078542 0,08962171 ! response to food GO:0032094 6 5 0,000 0,01078542 0,08931791 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01078542 0,08901616 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01078542 0,08871645 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01078542 0,08841874 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01078542 0,08812302 ! forebrain neuron development GO:0021884 13 5 0,000 0,01078542 0,08782928 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01078542 0,08753749 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01078542 0,08724763 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01078542 0,08695968 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01078542 0,08667363 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01078542 0,08638946 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01078542 0,08610714 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01078542 0,08582666 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01078542 0,085548 ! lipid glycosylation GO:0030259 7 5 0,000 0,01078542 0,08527115 ! nucleobase transport GO:0015851 6 5 0,000 0,01078542 0,08499608 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01078542 0,08472278 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01078542 0,08445123 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01078542 0,08418142 ! basic amino acid transport GO:0015802 12 5 0,000 0,01078542 0,08391333 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01078542 0,08364693 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01078542 0,08338223 ! actin nucleation GO:0045010 11 5 0,000 0,01078542 0,08311919 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01078542 0,08285781 ! depurination GO:0045007 5 5 0,000 0,01078542 0,08259807 ! depyrimidination GO:0045008 10 5 0,000 0,01078542 0,08233995 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01078542 0,08208344 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01078542 0,08182852 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01078542 0,08157518 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01078542 0,08132341 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01078542 0,08107318 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01078542 0,08082449 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01078542 0,08057732 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01078542 0,08033166 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01078542 0,08008749 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01078542 0,0798448 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01078542 0,07960358 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01078542 0,07936381 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01078542 0,07912548 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01078542 0,07888858 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01078542 0,07865309 ! response to arsenic GO:0046685 11 5 0,000 0,01078542 0,078419 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01078542 0,0781863 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01078542 0,07795498 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01078542 0,07772503 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01078542 0,07749642 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01078542 0,07726916 ! response to mercury ion GO:0046689 8 5 0,000 0,01078542 0,07704323 ! response to cadmium ion GO:0046686 7 5 0,000 0,01078542 0,07681861 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01078542 0,0765953 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01078542 0,07637329 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01078542 0,07615256 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01078542 0,0759331 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01078542 0,0757149 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01078542 0,07549795 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01078542 0,07528224 ! decidualization GO:0046697 11 5 0,000 0,01078542 0,07506776 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01078542 0,0748545 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01078542 0,07464245 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01078542 0,07443159 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01078542 0,07422193 ! embryonic cleavage GO:0040016 6 5 0,000 0,01078542 0,07401344 ! peroxisome fission GO:0016559 5 5 0,000 0,01078542 0,07380612 ! histone demethylation GO:0016577 13 5 0,000 0,01078542 0,07359996 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01078542 0,07339494 ! mitotic recombination GO:0006312 9 5 0,000 0,01078542 0,07319107 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01078542 0,07298832 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01078542 0,0727867 ! metaphase plate congression GO:0051310 7 5 0,000 0,01078542 0,07258618 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01078542 0,07238677 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01078542 0,07218845 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01078542 0,07199121 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01078542 0,07179505 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01078542 0,07159996 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01078542 0,07140592 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01078542 0,07121293 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01078542 0,07102098 ! B cell homeostasis GO:0001782 13 5 0,000 0,01078542 0,07083007 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01078542 0,07064017 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01078542 0,07045129 ! metaphase GO:0051323 11 5 0,000 0,01078542 0,07026342 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01078542 0,07007655 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01078542 0,06989067 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01078542 0,06970578 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01078542 0,06952186 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01078542 0,06933891 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01078542 0,06915691 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01078542 0,06897587 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01078542 0,06879578 ! response to redox state GO:0051775 6 5 0,000 0,01078542 0,06861663 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01078542 0,0684384 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01078542 0,0682611 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01078542 0,06808471 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01078542 0,06790924 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01078542 0,06773466 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01078542 0,06756099 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01078542 0,06738819 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01078542 0,06721629 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01078542 0,06704525 ! striatum development GO:0021756 14 5 0,000 0,01078542 0,06687509 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01078542 0,06670578 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01078542 0,06653733 ! glial cell migration GO:0008347 10 5 0,000 0,01078542 0,06636973 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01078542 0,06620298 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01078542 0,06603705 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01078542 0,06587196 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01078542 0,06570769 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01078542 0,06554424 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01078542 0,0653816 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01078542 0,06521976 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01078542 0,06505873 ! neuroprotection GO:0043526 8 5 0,000 0,01078542 0,06489848 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01078542 0,06473903 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01078542 0,06458035 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01078542 0,06442246 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01078542 0,06426533 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01078542 0,06410896 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01078542 0,06395336 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01078542 0,06379851 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01078542 0,06364441 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01078542 0,06349105 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01078542 0,06333842 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01078542 0,06318653 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01078542 0,06303537 ! spindle assembly GO:0051225 6 5 0,000 0,01078542 0,06288493 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01078542 0,0627352 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01078542 0,06258619 ! protein palmitoylation GO:0018345 12 5 0,000 0,01078542 0,06243788 ! drug metabolic process GO:0017144 7 5 0,000 0,01078542 0,06229027 ! stem cell division GO:0017145 11 5 0,000 0,01078542 0,06214336 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01078542 0,06199714 ! organ regeneration GO:0031100 7 5 0,000 0,01078542 0,06185161 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01078542 0,06170675 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01078542 0,06156258 ! appendage development GO:0048736 151 73 1,000 0,01102145 0,06276316 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 0,01131184 0,06426704 ! negative regulation of transferase activity GO:0051348 155 74 1,000 0,01131184 0,06411793 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01220309 0,06900962 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01220309 0,06885025 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01292869 0,072776 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01292869 0,0726087 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01292869 0,07244216 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01292869 0,07227639 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01292869 0,07211138 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01292869 0,07194711 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01292869 0,0717836 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01292869 0,07162082 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01292869 0,07145878 ! response to oxygen radical GO:0000305 11 6 0,000 0,01292869 0,07129748 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01292869 0,0711369 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01292869 0,07097704 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01292869 0,0708179 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01292869 0,07065947 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01292869 0,07050175 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01292869 0,07034473 ! forebrain regionalization GO:0021871 9 6 0,000 0,01292869 0,07018841 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01292869 0,07003278 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01292869 0,06987784 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01292869 0,06972358 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01292869 0,06957001 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01292869 0,0694171 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01292869 0,06926487 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01292869 0,06911331 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01292869 0,06896241 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01292869 0,06881216 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01292869 0,06866257 ! malate metabolic process GO:0006108 13 6 0,000 0,01292869 0,06851363 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01292869 0,06836533 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01292869 0,06821767 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01292869 0,06807065 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01292869 0,06792426 ! protein refolding GO:0042026 15 6 0,000 0,01292869 0,0677785 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01292869 0,06763337 ! opsonization GO:0008228 8 6 0,000 0,01292869 0,06748885 ! mating behavior GO:0007617 7 6 0,000 0,01292869 0,06734495 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01292869 0,06720166 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01292869 0,06705899 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01292869 0,06691691 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01292869 0,06677544 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01292869 0,06663456 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01292869 0,06649428 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01292869 0,06635459 ! toxin metabolic process GO:0009404 11 6 0,000 0,01292869 0,06621548 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01292869 0,06607695 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01292869 0,065939 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01292869 0,06580163 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01292869 0,06566483 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01292869 0,06552859 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01292869 0,06539292 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01292869 0,06525782 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01292869 0,06512326 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01292869 0,06498926 ! thymic T cell selection GO:0045061 16 6 0,000 0,01292869 0,06485582 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01292869 0,06472291 ! protein lipoylation GO:0009249 10 6 0,000 0,01292869 0,06459056 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01292869 0,06445874 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01292869 0,06432746 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01292869 0,06419671 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01292869 0,0640665 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01292869 0,06393681 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01292869 0,06380764 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01292869 0,063679 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01292869 0,06355087 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01292869 0,06342326 ! hyperosmotic response GO:0006972 10 6 0,000 0,01292869 0,06329616 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01292869 0,06316957 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01292869 0,06304348 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01292869 0,06291789 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01292869 0,06279281 ! urea metabolic process GO:0019627 7 6 0,000 0,01292869 0,06266822 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01292869 0,06254412 ! neutrophil activation GO:0042119 7 6 0,000 0,01292869 0,06242052 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01292869 0,0622974 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01292869 0,06217477 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01292869 0,06205262 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01292869 0,06193095 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01292869 0,06180975 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01292869 0,06168903 ! neuron apoptosis GO:0051402 15 6 0,000 0,01292869 0,06156878 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01292869 0,06144899 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01292869 0,06132967 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01292869 0,06121082 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01292869 0,06109242 ! carnitine transport GO:0015879 10 6 0,000 0,01292869 0,06097448 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01292869 0,060857 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01292869 0,06073997 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01292869 0,06062338 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01292869 0,06050725 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01292869 0,06039155 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01292869 0,0602763 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01292869 0,06016149 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01292869 0,06004712 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01292869 0,05993317 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01292869 0,05981966 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01292869 0,05970658 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01292869 0,05959393 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01292869 0,0594817 ! response to UV-C GO:0010225 14 6 0,000 0,01292869 0,05936989 ! astrocyte development GO:0014002 16 6 0,000 0,01292869 0,0592585 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01292869 0,05914753 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01292869 0,05903698 ! interaction with symbiont GO:0051702 14 6 0,000 0,01292869 0,05892683 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01292869 0,0588171 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01292869 0,05870777 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01292869 0,05859885 ! response to copper ion GO:0046688 10 6 0,000 0,01292869 0,05849034 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01292869 0,05838222 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01292869 0,05827451 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01292869 0,05816719 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01292869 0,05806026 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01292869 0,05795373 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01292869 0,05784759 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01292869 0,05774183 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01292869 0,05763646 ! hair follicle maturation GO:0048820 8 6 0,000 0,01292869 0,05753148 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01292869 0,05742688 ! Schwann cell development GO:0014044 15 6 0,000 0,01292869 0,05732265 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01292869 0,05721881 ! response to pheromone GO:0019236 6 6 0,000 0,01292869 0,05711534 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01292869 0,05701224 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01292869 0,05690952 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01292869 0,05680716 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01292869 0,05670518 ! subpallium development GO:0021544 15 6 0,000 0,01292869 0,05660355 ! neural tube patterning GO:0021532 8 6 0,000 0,01292869 0,05650229 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01292869 0,0564014 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01292869 0,05630086 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01292869 0,05620068 ! G2 phase GO:0051319 16 6 0,000 0,01292869 0,05610086 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01292869 0,05600139 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01292869 0,05590227 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01292869 0,0558035 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01292869 0,05570508 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01292869 0,05560701 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01292869 0,05550928 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01292869 0,0554119 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01292869 0,05531486 ! receptor internalization GO:0031623 11 6 0,000 0,01292869 0,05521815 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01292869 0,05512178 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01292869 0,05502575 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01292869 0,05493006 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01292869 0,05483469 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01292869 0,05473966 ! protein deubiquitination GO:0016579 16 6 0,000 0,01292869 0,05464495 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01292869 0,05455057 ! protein destabilization GO:0031648 9 6 0,000 0,01292869 0,05445652 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01292869 0,05436279 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01292869 0,05426939 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01292869 0,0541763 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01292869 0,05408353 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01292869 0,05399108 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01292869 0,05389895 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01292869 0,05380713 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01292869 0,05371562 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01292869 0,05362442 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01292869 0,05353353 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01292869 0,05344295 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01292869 0,05335267 ! neural plate development GO:0001840 9 6 0,000 0,01292869 0,0532627 ! catecholamine transport GO:0051937 9 6 0,000 0,01292869 0,05317303 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01292869 0,05308367 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01292869 0,0529946 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01292869 0,05290583 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01292869 0,05281736 ! maternal placenta development GO:0001893 12 6 0,000 0,01292869 0,05272919 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01292869 0,0526413 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01292869 0,05255371 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01292869 0,05246642 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01292869 0,05237941 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01292869 0,05229269 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01292869 0,05220625 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01292869 0,0521201 GO:0055081|anion homeostasis, ! response to hypoxia GO:0001666 178 81 1,000 0,01343769 0,05408282 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01343769 0,05399387 ! response to oxygen levels GO:0070482 183 83 1,000 0,01407453 0,05645991 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01407453 0,05636736 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01472425 0,05887291 ! tRNA transcription GO:0009304 17 7 0,000 0,01506737 0,06014638 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01506737 0,06004826 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01506737 0,05995046 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01506737 0,05985298 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01506737 0,05975582 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01506737 0,05965897 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01506737 0,05956243 ! sleep GO:0030431 16 7 0,000 0,01506737 0,05946621 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01506737 0,0593703 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01506737 0,05927469 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01506737 0,05917939 ! prostate gland development GO:0030850 14 7 0,000 0,01506737 0,0590844 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01506737 0,05898972 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01506737 0,05889533 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01506737 0,05880125 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01506737 0,05870747 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01506737 0,05861399 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01506737 0,0585208 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01506737 0,05842791 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01506737 0,05833531 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01506737 0,05824301 ! glycolipid transport GO:0046836 11 7 0,000 0,01506737 0,058151 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01506737 0,05805928 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01506737 0,05796785 ! neuron adhesion GO:0007158 14 7 0,000 0,01506737 0,0578767 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01506737 0,05778585 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01506737 0,05769527 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01506737 0,05760498 ! mRNA stabilization GO:0048255 18 7 0,000 0,01506737 0,05751497 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01506737 0,05742525 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01506737 0,0573358 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01506737 0,05724663 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01506737 0,05715774 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01506737 0,05706912 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01506737 0,05698078 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01506737 0,05689271 ! lipoprotein transport GO:0042953 14 7 0,000 0,01506737 0,05680491 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01506737 0,05671739 ! rhythmic behavior GO:0007622 17 7 0,000 0,01506737 0,05663013 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01506737 0,05654314 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01506737 0,05645642 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01506737 0,05636996 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01506737 0,05628377 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01506737 0,05619784 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01506737 0,05611217 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01506737 0,05602676 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01506737 0,05594162 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01506737 0,05585673 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01506737 0,0557721 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01506737 0,05568772 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01506737 0,0556036 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01506737 0,05551973 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01506737 0,05543612 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01506737 0,05535276 ! spinal cord patterning GO:0021511 14 7 0,000 0,01506737 0,05526964 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01506737 0,05518678 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01506737 0,05510417 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01506737 0,0550218 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01506737 0,05493968 ! adrenal gland development GO:0030325 17 7 0,000 0,01506737 0,0548578 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01506737 0,05477617 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01506737 0,05469477 ! ovulation GO:0030728 10 7 0,000 0,01506737 0,05461363 ! adenohypophysis development GO:0021984 11 7 0,000 0,01506737 0,05453272 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01506737 0,05445205 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01506737 0,05437161 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01506737 0,05429142 ! microtubule nucleation GO:0007020 21 7 0,000 0,01506737 0,05421146 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01506737 0,05413174 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01506737 0,05405225 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01506737 0,053973 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01506737 0,05389397 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01506737 0,05381518 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01506737 0,05373662 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01506737 0,05365828 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01506737 0,05358018 ! galactose metabolic process GO:0006012 13 7 0,000 0,01506737 0,0535023 ! response to dietary excess GO:0002021 8 7 0,000 0,01506737 0,05342465 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01506737 0,05334722 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01506737 0,05327002 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01506737 0,05319304 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01506737 0,05311628 ! organ growth GO:0035265 15 7 0,000 0,01506737 0,05303975 ! nucleoside transport GO:0015858 11 7 0,000 0,01506737 0,05296343 ! nucleoside salvage GO:0043174 11 7 0,000 0,01506737 0,05288733 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01506737 0,05281145 ! male sex determination GO:0030238 15 7 0,000 0,01506737 0,05273579 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01506737 0,05266035 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01506737 0,05258512 ! parturition GO:0007567 16 7 0,000 0,01506737 0,0525101 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01506737 0,0524353 ! rRNA modification GO:0000154 14 7 0,000 0,01506737 0,05236072 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01506737 0,05228634 ! spindle checkpoint GO:0031577 16 7 0,000 0,01506737 0,05221217 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01506737 0,05213822 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01506737 0,05206447 ! monocyte differentiation GO:0030224 16 7 0,000 0,01506737 0,05199094 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01506737 0,05191761 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01506737 0,05184448 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01506737 0,05177157 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01506737 0,05169885 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01506737 0,05162634 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01506737 0,05155404 ! fibrinolysis GO:0042730 11 7 0,000 0,01506737 0,05148193 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01506737 0,05141003 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01506737 0,05133833 ! eating behavior GO:0042755 8 7 0,000 0,01506737 0,05126683 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01506737 0,05119553 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01506737 0,05112442 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01506737 0,05105351 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01506737 0,0509828 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01506737 0,05091229 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01506737 0,05084197 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01506737 0,05077184 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01506737 0,05070191 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01506737 0,05063216 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01506737 0,05056261 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01506737 0,05049326 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01506737 0,05042409 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01506737 0,05035511 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01506737 0,05028632 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01506737 0,05021771 ! histone ubiquitination GO:0016574 9 7 0,000 0,01506737 0,0501493 ! regulation of meiosis GO:0040020 12 7 0,000 0,01506737 0,05008107 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01506737 0,05001302 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01506737 0,04994516 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01506737 0,04987748 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01506737 0,04980999 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01506737 0,04974268 ! transcription termination GO:0006353 14 7 0,000 0,01506737 0,04967555 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01506737 0,0496086 ! anaphase GO:0051322 18 7 0,000 0,01506737 0,04954183 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01506737 0,04947525 ! axonal fasciculation GO:0007413 19 7 0,000 0,01506737 0,04940884 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01506737 0,04934261 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01506737 0,04927655 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01506737 0,04921067 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01506737 0,04914497 ! diuresis GO:0030146 12 7 0,000 0,01506737 0,04907944 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01506737 0,04901409 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01506737 0,04894891 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01506737 0,04888391 ! antibiotic transport GO:0042891 9 7 0,000 0,01506737 0,04881908 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01506737 0,04875442 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01506737 0,04868993 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01506737 0,04862561 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01506737 0,04856146 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01506737 0,04849747 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01506737 0,04843366 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01506737 0,04837002 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01506737 0,04830654 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01506737 0,04824323 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01506737 0,04818008 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01506737 0,0481171 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01506737 0,04805429 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01506737 0,04799163 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01506737 0,04792914 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01506737 0,04786682 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01506737 0,04780465 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01506737 0,04774265 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01506737 0,04768081 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01506737 0,04761912 ! muscle adaptation GO:0043500 13 7 0,000 0,01506737 0,0475576 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01506737 0,04749624 ! retina homeostasis GO:0001895 12 7 0,000 0,01506737 0,04743503 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01506737 0,04737398 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01506737 0,04731309 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01506737 0,04725235 ! regulation of protein transport GO:0051223 165 87 1,000 0,01538672 0,048192 GO:0070201|regulation of establishment of protein localization, ! ossification GO:0001503 205 91 1,000 0,01674943 0,05239291 ! gland development GO:0048732 220 91 1,000 0,01674943 0,05232592 ! bone development GO:0060348 206 92 1,000 0,0170979 0,05334631 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01720148 0,05360103 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01720148 0,05353275 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01720148 0,05346464 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01720148 0,05339671 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01720148 0,05332895 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01720148 0,05326136 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01720148 0,05319394 ! male meiosis GO:0007140 9 8 0,000 0,01720148 0,05312669 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01720148 0,05305961 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01720148 0,0529927 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01720148 0,05292596 ! meiotic prophase I GO:0007128 14 8 0,000 0,01720148 0,05285938 ! response to zinc ion GO:0010043 12 8 0,000 0,01720148 0,05279298 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01720148 0,05272674 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01720148 0,05266066 ! oligopeptide transport GO:0006857 16 8 0,000 0,01720148 0,05259476 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01720148 0,05252901 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01720148 0,05246343 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01720148 0,05239802 ! signal peptide processing GO:0006465 12 8 0,000 0,01720148 0,05233277 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01720148 0,05226767 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01720148 0,05220275 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01720148 0,05213798 ! succinate metabolic process GO:0006105 17 8 0,000 0,01720148 0,05207337 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01720148 0,05200892 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01720148 0,05194464 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01720148 0,05188051 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01720148 0,05181654 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01720148 0,05175272 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01720148 0,05168907 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01720148 0,05162557 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01720148 0,05156222 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01720148 0,05149903 ! reflex GO:0060004 17 8 0,000 0,01720148 0,051436 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01720148 0,05137312 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01720148 0,05131039 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01720148 0,05124782 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01720148 0,0511854 ! pigment granule organization GO:0048753 17 8 0,000 0,01720148 0,05112313 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01720148 0,05106101 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01720148 0,05099904 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01720148 0,05093722 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01720148 0,05087556 ! histidine catabolic process GO:0006548 10 8 0,000 0,01720148 0,05081404 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01720148 0,05075267 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01720148 0,05069145 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01720148 0,05063037 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01720148 0,05056945 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01720148 0,05050867 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01720148 0,05044803 ! melanin metabolic process GO:0006582 17 8 0,000 0,01720148 0,05038754 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01720148 0,0503272 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01720148 0,050267 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01720148 0,05020694 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01720148 0,05014703 ! macrophage activation GO:0042116 13 8 0,000 0,01720148 0,05008726 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01720148 0,05002763 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01720148 0,04996815 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01720148 0,0499088 ! purine salvage GO:0043101 12 8 0,000 0,01720148 0,0498496 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01720148 0,04979053 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01720148 0,04973161 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01720148 0,04967283 ! osteoblast development GO:0002076 17 8 0,000 0,01720148 0,04961418 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01720148 0,04955567 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01720148 0,0494973 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01720148 0,04943907 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01720148 0,04938098 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01720148 0,04932302 ! response to UV-B GO:0010224 17 8 0,000 0,01720148 0,04926519 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01720148 0,04920751 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01720148 0,04914995 ! intermediate filament organization GO:0045109 12 8 0,000 0,01720148 0,04909254 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01720148 0,04903525 ! cellular extravasation GO:0045123 13 8 0,000 0,01720148 0,0489781 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01720148 0,04892108 ! response to antibiotic GO:0046677 11 8 0,000 0,01720148 0,0488642 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01720148 0,04880745 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01720148 0,04875082 ! DNA topological change GO:0006265 12 8 0,000 0,01720148 0,04869433 ! response to tropane GO:0014073 15 8 0,000 0,01720148 0,04863797 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01720148 0,04858175 ! melanosome transport GO:0032402 13 8 0,000 0,01720148 0,04852565 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01720148 0,04846968 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01720148 0,04841384 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01720148 0,04835812 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01720148 0,04830254 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01720148 0,04824708 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01720148 0,04819175 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01720148 0,04813655 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01720148 0,04808148 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01720148 0,04802653 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01720148 0,0479717 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01720148 0,047917 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01720148 0,04786243 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01720148 0,04780798 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01720148 0,04775365 ! response to tumor cell GO:0002347 16 8 0,000 0,01720148 0,04769944 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01720148 0,04764536 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01720148 0,0475914 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01720148 0,04753757 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01720148 0,04748385 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01720148 0,04743026 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01720148 0,04737679 ! hormone catabolic process GO:0042447 17 8 0,000 0,01720148 0,04732344 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01720148 0,0472702 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01720148 0,04721709 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01720148 0,0471641 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01720148 0,04711122 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01720148 0,04705847 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01720148 0,04700583 ! adult feeding behavior GO:0008343 10 8 0,000 0,01720148 0,04695331 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01720148 0,0469009 ! ATP catabolic process GO:0006200 11 8 0,000 0,01720148 0,04684862 ! blastocyst growth GO:0001832 19 8 0,000 0,01720148 0,04679645 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01720148 0,04674439 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01720148 0,04669246 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01720148 0,04664063 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01720148 0,04658892 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01720148 0,04653733 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01720148 0,04648585 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01720148 0,04643449 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01720148 0,04638323 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01720148 0,0463321 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01720148 0,04628107 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01720148 0,04623015 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01720148 0,04617935 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01720148 0,04612866 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01720148 0,04607808 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01720148 0,04602761 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01720148 0,04597725 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01720148 0,04592701 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01720148 0,04587687 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01744944 0,04648744 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01780406 0,04738051 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01816173 0,04827976 ! regulation of protein localization GO:0032880 188 97 1,000 0,01888617 0,050151 ! axon extension GO:0048675 16 9 0,000 0,01933102 0,05127653 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01933102 0,05122092 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01933102 0,05116542 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01933102 0,05111005 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01933102 0,0510548 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01933102 0,05099966 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01933102 0,05094465 ! reproductive behavior GO:0019098 22 9 0,000 0,01933102 0,05088975 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01933102 0,05083497 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01933102 0,05078031 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01933102 0,05072576 ! UTP metabolic process GO:0046051 10 9 0,000 0,01933102 0,05067134 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01933102 0,05061703 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01933102 0,05056283 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01933102 0,05050876 ! artery development GO:0060840 25 9 0,000 0,01933102 0,05045479 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01933102 0,05040095 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01933102 0,05034721 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01933102 0,0502936 ! equilibrioception GO:0050957 20 9 0,000 0,01933102 0,05024009 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01933102 0,0501867 ! chemosensory behavior GO:0007635 21 9 0,000 0,01933102 0,05013343 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01933102 0,05008026 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01933102 0,05002721 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01933102 0,04997427 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01933102 0,04992145 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01933102 0,04986873 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01933102 0,04981613 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01933102 0,04976363 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01933102 0,04971125 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01933102 0,04965898 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01933102 0,04960681 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01933102 0,04955476 ! protein targeting to ER GO:0045047 25 9 0,000 0,01933102 0,04950282 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01933102 0,04945098 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01933102 0,04939925 ! T cell selection GO:0045058 27 9 0,000 0,01933102 0,04934764 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01933102 0,04929612 ! glycine catabolic process GO:0006546 15 9 0,000 0,01933102 0,04924472 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01933102 0,04919342 ! endosome organization GO:0007032 20 9 0,000 0,01933102 0,04914223 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01933102 0,04909115 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01933102 0,04904017 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01933102 0,0489893 ! mannose metabolic process GO:0006013 13 9 0,000 0,01933102 0,04893854 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01933102 0,04888787 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01933102 0,04883732 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01933102 0,04878687 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01933102 0,04873652 ! receptor clustering GO:0043113 20 9 0,000 0,01933102 0,04868628 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01933102 0,04863613 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01933102 0,0485861 ! retinol metabolic process GO:0042572 20 9 0,000 0,01933102 0,04853616 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01933102 0,04848633 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01933102 0,0484366 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01933102 0,04838697 ! macrophage differentiation GO:0030225 15 9 0,000 0,01933102 0,04833745 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01933102 0,04828802 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01933102 0,0482387 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01933102 0,04818948 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01933102 0,04814035 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01933102 0,04809133 ! response to amine stimulus GO:0014075 13 9 0,000 0,01933102 0,04804241 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01933102 0,04799358 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01933102 0,04794486 ! erythrocyte development GO:0048821 17 9 0,000 0,01933102 0,04789623 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01933102 0,04784771 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01933102 0,04779928 ! renal water homeostasis GO:0003091 15 9 0,000 0,01933102 0,04775095 ! postreplication repair GO:0006301 25 9 0,000 0,01933102 0,04770271 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01933102 0,04765458 ! icosanoid secretion GO:0032309 15 9 0,000 0,01933102 0,04760654 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01933102 0,0475586 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01933102 0,04751075 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01933102 0,047463 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01933102 0,04741535 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01933102 0,04736779 ! sterol catabolic process GO:0016127 14 9 0,000 0,01933102 0,04732033 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01933102 0,04727296 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01933102 0,04722569 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01933102 0,04717851 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01933102 0,04713142 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01933102 0,04708443 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01933102 0,04703754 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01933102 0,04699073 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01933102 0,04694402 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01933102 0,04689741 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01933102 0,04685088 ! purine base metabolic process GO:0006144 25 9 0,000 0,01933102 0,04680445 ! pigment granule transport GO:0051904 17 9 0,000 0,01933102 0,04675811 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01933102 0,04671186 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01933102 0,0466657 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01933102 0,04661963 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01933102 0,04657366 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01933102 0,04652777 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01933102 0,04648198 ! mitochondrion localization GO:0051646 18 9 0,000 0,01933102 0,04643627 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02145601 0,05149021 ! regulation of developmental growth GO:0048638 16 10 0,000 0,02145601 0,05143968 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,02145601 0,05138925 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02145601 0,05133892 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02145601 0,05128869 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02145601 0,05123855 ! associative learning GO:0008306 21 10 0,000 0,02145601 0,05118851 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,02145601 0,05113857 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02145601 0,05108873 ! phosphate transport GO:0006817 24 10 0,000 0,02145601 0,05103898 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02145601 0,05098934 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02145601 0,05093978 ! CTP metabolic process GO:0046036 11 10 0,000 0,02145601 0,05089033 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02145601 0,05084097 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02145601 0,0507917 ! GTP metabolic process GO:0046039 11 10 0,000 0,02145601 0,05074253 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02145601 0,05069346 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02145601 0,05064448 ! social behavior GO:0035176 29 10 0,000 0,02145601 0,0505956 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02145601 0,05054681 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02145601 0,05049811 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02145601 0,05044951 ! androgen metabolic process GO:0008209 17 10 0,000 0,02145601 0,050401 ! phospholipid efflux GO:0033700 19 10 0,000 0,02145601 0,05035258 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02145601 0,05030426 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02145601 0,05025603 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02145601 0,05020789 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02145601 0,05015984 ! lung alveolus development GO:0048286 26 10 0,000 0,02145601 0,05011189 ! pathogenesis GO:0009405 17 10 0,000 0,02145601 0,05006403 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02145601 0,05001626 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02145601 0,04996858 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02145601 0,04992099 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02145601 0,04987349 ! endoderm development GO:0007492 18 10 0,000 0,02145601 0,04982608 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02145601 0,04977876 ! arginine catabolic process GO:0006527 17 10 0,000 0,02145601 0,04973153 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02145601 0,0496844 ! proline metabolic process GO:0006560 13 10 0,000 0,02145601 0,04963735 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02145601 0,04959039 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02145601 0,04954351 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02145601 0,04949673 ! V(D)J recombination GO:0033151 34 10 0,000 0,02145601 0,04945003 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02145601 0,04940343 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02145601 0,04935691 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02145601 0,04931048 ! B cell proliferation GO:0042100 19 10 0,000 0,02145601 0,04926413 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02145601 0,04921788 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02145601 0,0491717 ! multicellular organism growth GO:0035264 19 10 0,000 0,02145601 0,04912562 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02145601 0,04907962 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02145601 0,04903371 ! ruffle organization GO:0031529 17 10 0,000 0,02145601 0,04898789 ! epithelial cell development GO:0002064 21 10 0,000 0,02145601 0,04894214 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02145601 0,04889649 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02145601 0,04885092 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02145601 0,04880543 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02145601 0,04876003 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02145601 0,04871472 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02145601 0,04866949 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02145601 0,04862434 ! motor axon guidance GO:0008045 22 10 0,000 0,02145601 0,04857927 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02145601 0,04853429 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02145601 0,0484894 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02145601 0,04844458 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02145601 0,04839985 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02145601 0,0483552 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02145601 0,04831063 ! segment specification GO:0007379 15 10 0,000 0,02145601 0,04826615 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02145601 0,04822175 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02145601 0,04817742 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02145601 0,04813318 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02145601 0,04808902 ! response to dsRNA GO:0043331 23 10 0,000 0,02145601 0,04804495 ! DNA ligation GO:0006266 18 10 0,000 0,02145601 0,04800095 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02145601 0,04795703 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02145601 0,0479132 ! melanosome localization GO:0032400 16 10 0,000 0,02145601 0,04786944 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02145601 0,04782576 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02145601 0,04778217 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02145601 0,04773865 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02145601 0,04769521 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02145601 0,04765185 ! induction of an organ GO:0001759 17 10 0,000 0,02145601 0,04760857 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02145601 0,04756537 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02145601 0,04752225 ! protein sumoylation GO:0016925 17 10 0,000 0,02145601 0,0474792 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02145601 0,04743623 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02145601 0,04739334 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02145601 0,04735053 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02145601 0,0473078 ! salivary gland development GO:0007431 28 10 0,000 0,02145601 0,04726514 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02145601 0,04722256 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02145601 0,04718005 ! midbrain development GO:0030901 14 10 0,000 0,02145601 0,04713762 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02145601 0,04709527 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02145601 0,047053 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02145601 0,0470108 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02145601 0,04696867 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02145601 0,04692662 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02145601 0,04688465 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02145601 0,04684275 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02145601 0,04680093 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02145601 0,04675918 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02145601 0,0467175 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02145601 0,0466759 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02145601 0,04663437 ! blastocyst formation GO:0001825 18 10 0,000 0,02145601 0,04659292 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02145601 0,04655154 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02145601 0,04651024 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02145601 0,046469 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02145601 0,04642785 ! response to nicotine GO:0035094 20 10 0,000 0,02145601 0,04638676 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02145601 0,04634574 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02145601 0,0463048 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02357646 0,05083608 ! respiratory burst GO:0045730 17 11 0,000 0,02357646 0,05079126 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02357646 0,05074651 ! neuron fate specification GO:0048665 18 11 0,000 0,02357646 0,05070183 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02357646 0,05065724 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02357646 0,05061273 ! thyroid gland development GO:0030878 26 11 0,000 0,02357646 0,05056829 ! synapsis GO:0007129 14 11 0,000 0,02357646 0,05052393 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02357646 0,05047965 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02357646 0,05043545 ! response to pain GO:0048265 27 11 0,000 0,02357646 0,05039132 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02357646 0,05034728 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02357646 0,0503033 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02357646 0,05025941 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02357646 0,05021559 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02357646 0,05017185 ! bone resorption GO:0045453 16 11 0,000 0,02357646 0,05012818 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02357646 0,05008459 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02357646 0,05004108 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02357646 0,04999764 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02357646 0,04995428 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02357646 0,04991099 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02357646 0,04986778 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02357646 0,04982464 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02357646 0,04978158 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02357646 0,04973859 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02357646 0,04969567 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02357646 0,04965283 ! UV protection GO:0009650 20 11 0,000 0,02357646 0,04961006 ! adult heart development GO:0007512 16 11 0,000 0,02357646 0,04956737 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02357646 0,04952475 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02357646 0,0494822 ! macroautophagy GO:0016236 19 11 0,000 0,02357646 0,04943973 ! temperature homeostasis GO:0001659 18 11 0,000 0,02357646 0,04939733 ! behavioral fear response GO:0001662 27 11 0,000 0,02357646 0,049355 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02357646 0,04931274 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02357646 0,04927056 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02357646 0,04922845 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02357646 0,04918641 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02357646 0,04914444 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02357646 0,04910254 ! regulation of organ growth GO:0046620 14 11 0,000 0,02357646 0,04906072 ! pigment granule localization GO:0051875 20 11 0,000 0,02357646 0,04901896 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02357646 0,04897728 ! vasoconstriction GO:0042310 20 11 0,000 0,02357646 0,04893567 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02357646 0,04889413 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02357646 0,04885266 ! embryonic axis specification GO:0000578 19 11 0,000 0,02357646 0,04881126 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02357646 0,04876993 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02357646 0,04872867 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02357646 0,04868748 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02357646 0,04864635 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02357646 0,0486053 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02357646 0,04856432 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02357646 0,04852341 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02357646 0,04848256 ! prophase GO:0051324 17 11 0,000 0,02357646 0,04844179 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02357646 0,04840108 ! nucleosome positioning GO:0016584 15 11 0,000 0,02357646 0,04836044 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02357646 0,04831987 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02357646 0,04827937 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02357646 0,04823893 ! apical protein localization GO:0045176 18 11 0,000 0,02357646 0,04819856 ! acid secretion GO:0046717 20 11 0,000 0,02357646 0,04815826 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02357646 0,04811803 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02357646 0,04807787 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02357646 0,04803777 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02357646 0,04799774 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02357646 0,04795777 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02357646 0,04791787 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02357646 0,04787804 ! cholesterol efflux GO:0033344 21 11 0,000 0,02357646 0,04783828 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02357646 0,04779858 ! oocyte development GO:0048599 20 11 0,000 0,02357646 0,04775894 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02357646 0,04771937 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02357646 0,04767987 ! embryonic gut development GO:0048566 19 11 0,000 0,02357646 0,04764043 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02357646 0,04760106 ! activation of innate immune response GO:0002218 16 11 0,000 0,02357646 0,04756175 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02357646 0,04752251 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02357646 0,04748333 ! lysogeny GO:0030069 22 11 0,000 0,02357646 0,04744422 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02357646 0,04740517 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02357646 0,04736619 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02357646 0,04732727 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02357646 0,04728841 ! nucleus localization GO:0051647 22 11 0,000 0,02357646 0,04724962 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02569237 0,05144791 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02569237 0,05140577 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02569237 0,05136371 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02569237 0,05132171 ! virus-host interaction GO:0019048 30 12 0,000 0,02569237 0,05127978 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,02569237 0,05123792 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02569237 0,05119613 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02569237 0,0511544 ! protein complex disassembly GO:0043241 28 12 0,000 0,02569237 0,05111274 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02569237 0,05107116 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02569237 0,05102963 ! hippocampus development GO:0021766 29 12 0,000 0,02569237 0,05098818 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02569237 0,05094679 ! T cell proliferation GO:0042098 32 12 0,000 0,02569237 0,05090548 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02569237 0,05086422 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02569237 0,05082304 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02569237 0,05078192 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02569237 0,05074087 ! drug transport GO:0015893 16 12 0,000 0,02569237 0,05069988 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02569237 0,05065896 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02569237 0,05061811 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02569237 0,05057732 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02569237 0,05053659 ! focal adhesion formation GO:0048041 37 12 0,000 0,02569237 0,05049594 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02569237 0,05045535 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02569237 0,05041482 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02569237 0,05037436 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02569237 0,05033396 ! lipid digestion GO:0044241 21 12 0,000 0,02569237 0,05029363 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02569237 0,05025336 ! entry into host cell GO:0030260 34 12 0,000 0,02569237 0,05021316 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02569237 0,05017302 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02569237 0,05013295 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02569237 0,05009294 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02569237 0,05005299 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02569237 0,05001311 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02569237 0,04997329 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02569237 0,04993353 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02569237 0,04989384 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02569237 0,04985421 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02569237 0,04981464 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02569237 0,04977514 ! cranial nerve development GO:0021545 23 12 0,000 0,02569237 0,0497357 ! fucose catabolic process GO:0019317 25 12 0,000 0,02569237 0,04969632 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02569237 0,049657 ! histone acetylation GO:0016573 27 12 0,000 0,02569237 0,04961775 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02569237 0,04957856 ! zymogen activation GO:0031638 18 12 0,000 0,02569237 0,04953942 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02569237 0,04950036 ! T cell homeostasis GO:0043029 28 12 0,000 0,02569237 0,04946135 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02569237 0,0494224 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02569237 0,04938352 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02569237 0,04934469 ! oocyte differentiation GO:0009994 21 12 0,000 0,02569237 0,04930593 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02569237 0,04926723 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02569237 0,04922859 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02569237 0,04919001 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02569237 0,04915149 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02569237 0,04911303 ! defense response to fungus GO:0050832 15 12 0,000 0,02569237 0,04907463 ! developmental induction GO:0031128 22 12 0,000 0,02569237 0,04903629 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02569237 0,04899801 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02569237 0,04895979 ! response to cold GO:0009409 17 12 0,000 0,02569237 0,04892163 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02569237 0,04888353 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02569237 0,04884549 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02780375 0,05281848 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02780375 0,05277744 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02780375 0,05273646 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02780375 0,05269555 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02780375 0,0526547 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02780375 0,05261391 ! peroxisomal transport GO:0043574 28 13 0,000 0,02780375 0,05257319 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02780375 0,05253253 ! cartilage condensation GO:0001502 22 13 0,000 0,02780375 0,05249193 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02780375 0,0524514 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02780375 0,05241093 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02780375 0,05237052 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02780375 0,05233017 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02780375 0,05228989 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02780375 0,05224966 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02780375 0,0522095 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02780375 0,0521694 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02780375 0,05212936 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02780375 0,05208939 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02780375 0,05204947 ! methionine metabolic process GO:0006555 31 13 0,000 0,02780375 0,05200962 ! plasma membrane organization GO:0007009 27 13 0,000 0,02780375 0,05196982 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02780375 0,05193009 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02780375 0,05189042 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02780375 0,05185081 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02780375 0,05181126 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02780375 0,05177177 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02780375 0,05173234 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02780375 0,05169297 ! exocrine system development GO:0035272 34 13 0,000 0,02780375 0,05165366 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02780375 0,05161441 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02780375 0,05157522 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02780375 0,05153609 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02780375 0,05149701 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02780375 0,051458 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02780375 0,05141905 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02780375 0,05138015 ! protein homotetramerization GO:0051289 24 13 0,000 0,02780375 0,05134132 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02780375 0,05130254 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02780375 0,05126382 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02780375 0,05122516 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02780375 0,05118656 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02780375 0,05114801 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02780375 0,05110953 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02780375 0,0510711 ! histone methylation GO:0016571 29 13 0,000 0,02780375 0,05103273 ! chromatin silencing GO:0006342 29 13 0,000 0,02780375 0,05099442 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02780375 0,05095616 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02780375 0,05091796 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02780375 0,05087982 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02780375 0,05084174 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02780375 0,05080371 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02780375 0,05076574 ! spleen development GO:0048536 24 13 0,000 0,02780375 0,05072783 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02780375 0,05068997 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02780375 0,05065217 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02780375 0,05061443 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02780375 0,05057674 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02780375 0,05053911 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02780375 0,05050153 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02780375 0,05046401 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02780375 0,05042655 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02780375 0,05038914 ! insulin secretion GO:0030073 24 13 0,000 0,02780375 0,05035179 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02780375 0,05031449 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02780375 0,05027725 ! acrosome reaction GO:0007340 19 13 0,000 0,02780375 0,05024006 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02780375 0,05020293 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02780375 0,05016585 ! rRNA transcription GO:0009303 28 14 0,000 0,02991062 0,05392741 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02991062 0,05388764 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02991062 0,05384793 ! water transport GO:0006833 21 14 0,000 0,02991062 0,05380828 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02991062 0,05376868 ! non-recombinational repair GO:0000726 29 14 0,000 0,02991062 0,05372915 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02991062 0,05368967 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02991062 0,05365025 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02991062 0,05361089 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02991062 0,05357158 ! palate development GO:0060021 32 14 0,000 0,02991062 0,05353234 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02991062 0,05349315 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02991062 0,05345402 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02991062 0,05341494 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02991062 0,05337592 ! arginine metabolic process GO:0006525 21 14 0,000 0,02991062 0,05333696 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02991062 0,05329806 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02991062 0,05325921 ! regulation of heart rate GO:0002027 25 14 0,000 0,02991062 0,05322042 ! fear response GO:0042596 34 14 0,000 0,02991062 0,05318169 ! organic alcohol transport GO:0015850 29 14 0,000 0,02991062 0,05314301 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02991062 0,05310439 ! embryo implantation GO:0007566 30 14 0,000 0,02991062 0,05306582 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02991062 0,05302731 ! bone mineralization GO:0030282 18 14 0,000 0,02991062 0,05298886 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02991062 0,05295046 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02991062 0,05291212 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02991062 0,05287383 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02991062 0,0528356 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02991062 0,05279743 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02991062 0,05275931 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02991062 0,05272124 ! ribosome assembly GO:0042255 18 14 0,000 0,02991062 0,05268323 ! cerebellum development GO:0021549 23 14 0,000 0,02991062 0,05264527 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02991062 0,05260737 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02991062 0,05256952 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02991062 0,05253173 ! response to gamma radiation GO:0010332 30 14 0,000 0,02991062 0,05249399 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02991062 0,05245631 ! NADP metabolic process GO:0006739 24 14 0,000 0,02991062 0,05241868 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02991062 0,0523811 ! oxygen transport GO:0015671 22 14 0,000 0,02991062 0,05234358 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02991062 0,05230611 ! male genitalia development GO:0030539 26 14 0,000 0,02991062 0,0522687 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02991062 0,05223134 ! regulation of axon extension GO:0030516 43 14 0,000 0,02991062 0,05219403 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02991062 0,05215677 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02991062 0,05211957 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03201298 0,0557432 ! lactation GO:0007595 30 15 0,000 0,03201298 0,05570349 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,03201298 0,05566385 ! reproductive cellular process GO:0048610 22 15 0,000 0,03201298 0,05562426 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03201298 0,05558472 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03201298 0,05554525 ! superoxide anion generation GO:0042554 22 15 0,000 0,03201298 0,05550582 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03201298 0,05546646 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03201298 0,05542715 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03201298 0,05538789 ! copper ion transport GO:0006825 22 15 0,000 0,03201298 0,0553487 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03201298 0,05530955 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03201298 0,05527046 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03201298 0,05523143 ! sulfate transport GO:0008272 27 15 0,000 0,03201298 0,05519245 ! response to cAMP GO:0051591 25 15 0,000 0,03201298 0,05515353 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03201298 0,05511466 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03201298 0,05507585 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03201298 0,05503709 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03201298 0,05499839 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03201298 0,05495974 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03201298 0,05492114 ! vesicle coating GO:0006901 38 15 0,000 0,03201298 0,0548826 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03201298 0,05484411 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03201298 0,05480568 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,03201298 0,0547673 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03201298 0,05472898 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03201298 0,0546907 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,03201298 0,05465249 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03201298 0,05461432 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03201298 0,05457621 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03201298 0,05453815 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03201298 0,05450014 ! histone deacetylation GO:0016575 24 15 0,000 0,03201298 0,05446219 ! water homeostasis GO:0030104 28 15 0,000 0,03201298 0,05442429 ! cofactor transport GO:0051181 30 15 0,000 0,03201298 0,05438644 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03201298 0,05434865 ! muscle maintenance GO:0046716 26 15 0,000 0,03201298 0,05431091 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03201298 0,05427322 ! intestinal absorption GO:0050892 31 15 0,000 0,03201298 0,05423558 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03201298 0,05419799 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03201298 0,05416046 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03201298 0,05412298 ! cell killing GO:0001906 32 15 0,000 0,03201298 0,05408555 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03201298 0,05404817 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03201298 0,05401085 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03201298 0,05397357 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03201298 0,05393635 ! actin filament polymerization GO:0030041 27 15 0,000 0,03201298 0,05389918 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03201298 0,05386206 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03411084 0,05735223 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03411084 0,05731278 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03411084 0,05727339 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03411084 0,05723406 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03411084 0,05719478 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03411084 0,05715555 ! bone remodeling GO:0046849 28 16 0,000 0,03411084 0,05711637 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03411084 0,05707725 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03411084 0,05703818 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03411084 0,05699917 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03411084 0,05696021 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03411084 0,0569213 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03411084 0,05688245 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03411084 0,05684365 ! startle response GO:0001964 28 16 0,000 0,03411084 0,0568049 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03411084 0,0567662 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03411084 0,05672756 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03411084 0,05668897 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03411084 0,05665043 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03411084 0,05661195 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03411084 0,05657351 ! pituitary gland development GO:0021983 30 16 0,000 0,03411084 0,05653513 ! response to osmotic stress GO:0006970 27 16 0,000 0,03411084 0,05649681 ! lysosomal transport GO:0007041 31 16 0,000 0,03411084 0,05645853 ! fructose metabolic process GO:0006000 25 16 0,000 0,03411084 0,0564203 ! L-amino acid transport GO:0015807 33 16 0,000 0,03411084 0,05638213 ! stem cell development GO:0048864 46 16 0,000 0,03411084 0,05634401 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03411084 0,05630594 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03411084 0,05626792 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03411084 0,05622995 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03411084 0,05619203 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03411084 0,05615417 ! axon cargo transport GO:0008088 46 16 0,000 0,03411084 0,05611636 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03411084 0,05607859 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03411084 0,05604088 ! DNA replication initiation GO:0006270 28 16 0,000 0,03411084 0,05600322 ! neuron recognition GO:0008038 40 16 0,000 0,03411084 0,05596561 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03411084 0,05592805 ! tissue regeneration GO:0042246 27 16 0,000 0,03411084 0,05589053 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03411084 0,05585307 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03411084 0,05581566 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03411084 0,0557783 ! biomineral formation GO:0031214 22 16 0,000 0,03411084 0,05574099 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03411084 0,05570373 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03411084 0,05566652 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03411084 0,05562936 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03411084 0,05559225 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03411084 0,05555519 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03411084 0,05551818 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03411084 0,05548122 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03411084 0,0554443 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03411084 0,05540744 ! peptide hormone processing GO:0016486 27 16 0,000 0,03411084 0,05537062 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03620422 0,05872968 ! metencephalon development GO:0022037 32 17 0,000 0,03620422 0,05869071 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03620422 0,05865179 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03620422 0,05861293 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03620422 0,05857411 ! signal complex assembly GO:0007172 47 17 0,000 0,03620422 0,05853534 ! filopodium assembly GO:0046847 42 17 0,000 0,03620422 0,05849663 ! endothelial cell migration GO:0043542 31 17 0,000 0,03620422 0,05845797 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03620422 0,05841936 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03620422 0,0583808 ! glial cell development GO:0021782 28 17 0,000 0,03620422 0,05834229 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03620422 0,05830383 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03620422 0,05826542 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03620422 0,05822706 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03620422 0,05818875 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03620422 0,0581505 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03620422 0,05811229 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03620422 0,05807413 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03620422 0,05803603 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03620422 0,05799797 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03620422 0,05795996 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03620422 0,05792201 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03620422 0,0578841 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03620422 0,05784624 ! membrane budding GO:0006900 42 17 0,000 0,03620422 0,05780843 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03620422 0,05777068 ! regulation of protein binding GO:0043393 33 17 0,000 0,03620422 0,05773297 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03620422 0,05769531 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03620422 0,0576577 ! genitalia development GO:0048806 32 17 0,000 0,03620422 0,05762013 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03620422 0,05758262 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03620422 0,05754516 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03620422 0,05750774 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03620422 0,05747037 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03620422 0,05743306 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03620422 0,05739579 ! steroid catabolic process GO:0006706 34 17 0,000 0,03620422 0,05735856 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03620422 0,05732139 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03620422 0,05728427 ! gas transport GO:0015669 26 17 0,000 0,03620422 0,05724719 ! organic cation transport GO:0015695 32 17 0,000 0,03620422 0,05721016 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03620422 0,05717318 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03620422 0,05713624 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03620422 0,05709936 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03829312 0,06035489 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03829312 0,06031598 ! limbic system development GO:0021761 40 18 0,000 0,03829312 0,06027712 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03829312 0,0602383 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03829312 0,06019954 ! adult walking behavior GO:0007628 36 18 0,000 0,03829312 0,06016082 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03829312 0,06012216 ! heart looping GO:0001947 34 18 0,000 0,03829312 0,06008355 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03829312 0,06004498 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03829312 0,06000647 ! centrosome cycle GO:0007098 26 18 0,000 0,03829312 0,059968 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03829312 0,05992959 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03829312 0,05989122 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03829312 0,0598529 ! glycine metabolic process GO:0006544 30 18 0,000 0,03829312 0,05981463 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03829312 0,05977641 ! response to retinoic acid GO:0032526 31 18 0,000 0,03829312 0,05973824 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03829312 0,05970012 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03829312 0,05966204 ! DNA integration GO:0015074 32 18 0,000 0,03829312 0,05962402 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03829312 0,05958604 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03829312 0,05954811 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03829312 0,05951023 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03829312 0,0594724 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03829312 0,05943461 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03829312 0,05939688 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03829312 0,05935919 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03829312 0,05932155 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03829312 0,05928396 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03829312 0,05924641 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03829312 0,05920891 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03829312 0,05917146 ! detection of bacterium GO:0016045 22 18 0,000 0,03829312 0,05913406 ! nerve development GO:0021675 34 18 0,000 0,03829312 0,0590967 ! defense response to virus GO:0051607 43 18 0,000 0,03829312 0,0590594 ! microspike assembly GO:0030035 46 18 0,000 0,03829312 0,05902213 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03829312 0,05898492 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03829312 0,05894775 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04037755 0,06211734 ! positive regulation of translation GO:0045727 31 19 0,000 0,04037755 0,06207825 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04037755 0,06203921 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,04037755 0,06200022 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04037755 0,06196127 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04037755 0,06192237 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04037755 0,06188353 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04037755 0,06184473 ! inositol metabolic process GO:0006020 33 19 0,000 0,04037755 0,06180598 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04037755 0,06176728 ! memory GO:0007613 34 19 0,000 0,04037755 0,06172863 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04037755 0,06169002 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04037755 0,06165146 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04037755 0,06161296 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04037755 0,0615745 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,04037755 0,06153608 ! cerebral cortex development GO:0021987 40 19 0,000 0,04037755 0,06149772 ! pigmentation during development GO:0048066 42 19 0,000 0,04037755 0,0614594 ! response to vitamin A GO:0033189 32 19 0,000 0,04037755 0,06142114 ! heme metabolic process GO:0042168 40 19 0,000 0,04037755 0,06138291 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04037755 0,06134474 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04037755 0,06130661 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04037755 0,06126854 ! response to fungus GO:0009620 26 19 0,000 0,04037755 0,0612305 ! peptide cross-linking GO:0018149 39 19 0,000 0,04037755 0,06119252 ! protein export from nucleus GO:0006611 40 19 0,000 0,04037755 0,06115458 ! heart process GO:0003015 32 19 0,000 0,04037755 0,06111669 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04037755 0,06107885 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04037755 0,06104105 ! visual learning GO:0008542 38 19 0,000 0,04037755 0,0610033 ! cellular pigmentation GO:0033059 37 19 0,000 0,04037755 0,0609656 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04037755 0,06092795 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04037755 0,06089034 ! vitamin transport GO:0051180 31 19 0,000 0,04037755 0,06085277 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04037755 0,06081525 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04037755 0,06077778 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04037755 0,06074036 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04037755 0,06070298 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04037755 0,06066565 ! cilium assembly GO:0042384 38 19 0,000 0,04037755 0,06062836 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04037755 0,06059112 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04245752 0,06367324 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04245752 0,06363418 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04245752 0,06359516 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04245752 0,06355619 ! skin development GO:0043588 42 20 0,000 0,04245752 0,06351727 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04245752 0,0634784 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04245752 0,06343958 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04245752 0,0634008 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04245752 0,06336207 ! response to vitamin GO:0033273 36 20 0,000 0,04245752 0,06332339 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04245752 0,06328475 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04245752 0,06324616 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04245752 0,06320762 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04245752 0,06316913 ! response to alkaloid GO:0043279 38 20 0,000 0,04245752 0,06313068 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04245752 0,06309228 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04245752 0,06305393 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04245752 0,06301562 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04245752 0,06297736 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04245752 0,06293914 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04245752 0,06290098 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04245752 0,06286285 ! body fluid secretion GO:0007589 33 20 0,000 0,04245752 0,06282478 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04245752 0,06278675 ! peptide secretion GO:0002790 38 20 0,000 0,04245752 0,06274877 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04245752 0,06271083 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04245752 0,06267294 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04245752 0,06263509 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04245752 0,06259729 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04245752 0,06255954 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04245752 0,06252183 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04245752 0,06248416 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04245752 0,06244654 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04245752 0,06240897 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04245752 0,06237144 ! regulation of glucose import GO:0046324 30 20 0,000 0,04245752 0,06233396 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04245752 0,06229652 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04245752 0,06225913 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04245752 0,06222178 ! negative regulation of translation GO:0017148 32 20 0,000 0,04245752 0,06218448 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04245752 0,06214722 ! regulation of cell killing GO:0031341 46 21 0,000 0,04453304 0,06514623 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04453304 0,06510724 ! hormone secretion GO:0046879 39 21 0,000 0,04453304 0,0650683 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04453304 0,06502941 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04453304 0,06499056 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04453304 0,06495176 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04453304 0,06491301 ! ovarian follicle development GO:0001541 39 21 0,000 0,04453304 0,0648743 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04453304 0,06483564 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04453304 0,06479702 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04453304 0,06475846 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04453304 0,06471993 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04453304 0,06468145 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04453304 0,06464302 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04453304 0,06460463 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04453304 0,06456629 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04453304 0,064528 ! diencephalon development GO:0021536 36 21 0,000 0,04453304 0,06448975 ! collagen fibril organization GO:0030199 62 21 0,000 0,04453304 0,06445154 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04453304 0,06441338 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04453304 0,06437527 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04453304 0,0643372 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04453304 0,06429918 ! collagen catabolic process GO:0030574 29 21 0,000 0,04453304 0,0642612 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04453304 0,06422326 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04453304 0,06418537 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04453304 0,06414753 ! actin filament-based movement GO:0030048 47 21 0,000 0,04453304 0,06410973 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04453304 0,06407197 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04660411 0,06701227 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04660411 0,06697285 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04660411 0,06693348 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04660411 0,06689416 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04660411 0,06685487 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04660411 0,06681564 ! microtubule-based transport GO:0010970 59 22 0,000 0,04660411 0,06677645 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04660411 0,06673731 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04660411 0,06669821 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04660411 0,06665916 ! cellular response to starvation GO:0009267 37 22 0,000 0,04660411 0,06662016 ! vacuolar transport GO:0007034 41 22 0,000 0,04660411 0,0665812 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04660411 0,06654229 ! fucose metabolic process GO:0006004 44 22 0,000 0,04660411 0,06650342 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04660411 0,0664646 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04660411 0,06642582 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04660411 0,06638709 ! cell aging GO:0007569 48 22 0,000 0,04660411 0,0663484 ! stem cell differentiation GO:0048863 57 22 0,000 0,04660411 0,06630976 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04660411 0,06627116 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04660411 0,06623261 ! cytolysis GO:0019835 27 22 0,000 0,04660411 0,0661941 ! renal system process GO:0003014 42 22 0,000 0,04660411 0,06615564 ! vasodilation GO:0042311 40 22 0,000 0,04660411 0,06611722 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04660411 0,06607885 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04660411 0,06604052 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04660411 0,06600223 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04660411 0,06596399 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04660411 0,0659258 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04660411 0,06588765 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04660411 0,06584954 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04660411 0,06581148 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04660411 0,06577346 ! sarcomere organization GO:0045214 32 22 0,000 0,04660411 0,06573548 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,04660411 0,06569755 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04660411 0,06565966 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04660411 0,06562182 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04660411 0,06558402 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04660411 0,06554626 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04660411 0,06550855 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04660411 0,06547088 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04660411 0,06543325 ! protein stabilization GO:0050821 41 22 0,000 0,04660411 0,06539566 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04867076 0,06825641 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04867076 0,06821725 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04867076 0,06817814 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04867076 0,06813907 ! gluconeogenesis GO:0006094 38 23 0,000 0,04867076 0,06810004 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04867076 0,06806106 ! viral genome replication GO:0019079 44 23 0,000 0,04867076 0,06802212 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04867076 0,06798323 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04867076 0,06794439 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04867076 0,06790558 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04867076 0,06786682 ! regeneration GO:0031099 42 23 0,000 0,04867076 0,06782811 ! axis specification GO:0009798 43 23 0,000 0,04867076 0,06778944 ! visual behavior GO:0007632 46 23 0,000 0,04867076 0,06775081 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04867076 0,06771223 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04867076 0,06767369 ! response to ethanol GO:0045471 47 23 0,000 0,04867076 0,0676352 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04867076 0,06759674 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04867076 0,06755834 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04867076 0,06751997 ! peroxisome organization GO:0007031 43 23 0,000 0,04867076 0,06748165 ! lysosome organization GO:0007040 47 23 0,000 0,04867076 0,06744338 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04867076 0,06740514 ! vesicle targeting GO:0006903 49 23 0,000 0,04867076 0,06736695 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04867076 0,06732881 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04867076 0,0672907 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04867076 0,06725264 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04867076 0,06721463 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04867076 0,06717665 ! DNA modification GO:0006304 36 23 0,000 0,04867076 0,06713872 ! fatty acid transport GO:0015908 47 23 0,000 0,04867076 0,06710083 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04867076 0,06706299 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04867076 0,06702518 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04867076 0,06698742 ! hormone transport GO:0009914 41 23 0,000 0,04867076 0,0669497 ! cell-cell recognition GO:0009988 28 23 0,000 0,04867076 0,06691203 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04867076 0,06687439 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04867076 0,0668368 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04867076 0,06679926 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05073299 0,06959051 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05073299 0,06955146 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,05073299 0,06951245 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,05073299 0,06947348 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05073299 0,06943456 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05073299 0,06939569 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05073299 0,06935685 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05073299 0,06931806 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05073299 0,06927931 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05073299 0,06924061 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05073299 0,06920195 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05073299 0,06916333 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05073299 0,06912476 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05073299 0,06908623 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05073299 0,06904774 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05073299 0,06900929 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05073299 0,06897089 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05073299 0,06893253 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05073299 0,06889422 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,05073299 0,06885594 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05073299 0,06881771 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05073299 0,06877952 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05073299 0,06874137 ! pallium development GO:0021543 56 24 0,000 0,05073299 0,06870327 ! oogenesis GO:0048477 44 24 0,000 0,05073299 0,0686652 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05073299 0,06862718 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05073299 0,06858921 ! platelet activation GO:0030168 41 24 0,000 0,05073299 0,06855127 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05073299 0,06851337 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05073299 0,06847552 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05073299 0,06843771 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05073299 0,06839994 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05073299 0,06836221 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05073299 0,06832453 ! regulation of amine transport GO:0051952 41 24 0,000 0,05073299 0,06828688 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0527908 0,07101758 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0527908 0,0709785 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0527908 0,07093946 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0527908 0,07090046 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0527908 0,0708615 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0527908 0,07082259 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0527908 0,07078372 ! phototransduction GO:0007602 37 25 0,000 0,0527908 0,07074489 ! keratinization GO:0031424 37 25 0,000 0,0527908 0,0707061 ! vacuole organization GO:0007033 49 25 0,000 0,0527908 0,07066736 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0527908 0,07062866 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0527908 0,07059 ! receptor metabolic process GO:0043112 53 25 0,000 0,0527908 0,07055139 ! chromosome condensation GO:0030261 48 25 0,000 0,0527908 0,07051281 ! regulation of behavior GO:0050795 48 25 0,000 0,0527908 0,07047428 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0527908 0,07043579 ! interaction with host GO:0051701 66 25 0,000 0,0527908 0,07039734 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0527908 0,07035894 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0527908 0,07032057 ! immunoglobulin production GO:0002377 62 25 0,000 0,0527908 0,07028225 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0527908 0,07024397 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0527908 0,07020573 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0527908 0,07016754 ! liver development GO:0001889 55 25 0,000 0,0527908 0,07012938 ! protein tetramerization GO:0051262 57 25 0,000 0,0527908 0,07009127 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05484421 0,07277806 ! myelination GO:0042552 50 26 0,000 0,05484421 0,07273855 ! initiation of viral infection GO:0019059 60 26 0,000 0,05484421 0,07269909 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05484421 0,07265966 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05484421 0,07262028 ! molting cycle process GO:0022404 52 26 0,000 0,05484421 0,07258094 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05484421 0,07254164 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05484421 0,07250239 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05484421 0,07246318 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05484421 0,07242401 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05484421 0,07238488 ! digestive system process GO:0022600 49 26 0,000 0,05484421 0,0723458 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05484421 0,07230675 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,05484421 0,07226775 GO:0045936|negative regulation of phosphate metabolic process, ! osteoblast differentiation GO:0001649 63 26 0,000 0,05484421 0,0722288 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05484421 0,07218988 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05484421 0,07215101 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05484421 0,07211217 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05484421 0,07207338 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05484421 0,07203463 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05484421 0,07199593 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05484421 0,07195726 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05484421 0,07191863 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05484421 0,07188005 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05484421 0,07184151 ! blastocyst development GO:0001824 50 26 0,000 0,05484421 0,07180301 ! telomere organization GO:0032200 46 26 0,000 0,05484421 0,07176455 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05484421 0,07172613 ! neural tube closure GO:0001843 58 26 0,000 0,05484421 0,07168776 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05484421 0,07164942 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05484421 0,07161113 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05484421 0,07157287 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05689323 0,07420724 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05689323 0,07416764 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05689323 0,07412809 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05689323 0,07408857 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05689323 0,0740491 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05689323 0,07400967 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05689323 0,07397029 ! iron ion transport GO:0006826 65 27 0,000 0,05689323 0,07393094 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05689323 0,07389164 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05689323 0,07385237 ! tube lumen formation GO:0035148 59 27 0,000 0,05689323 0,07381315 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05689323 0,07377397 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,05689323 0,07373484 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05689323 0,07369574 ! response to starvation GO:0042594 47 27 0,000 0,05689323 0,07365669 ! response to toxin GO:0009636 49 27 0,000 0,05689323 0,07361767 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05689323 0,0735787 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05689323 0,07353977 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,05689323 0,07350088 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05689323 0,07346203 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05689323 0,07342323 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05689323 0,07338446 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,05893786 0,07598164 ! neuron fate commitment GO:0048663 52 28 0,000 0,05893786 0,07594156 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05893786 0,07590153 ! protein amino acid acylation GO:0043543 59 28 0,000 0,05893786 0,07586154 ! circadian rhythm GO:0007623 56 28 0,000 0,05893786 0,07582159 ! dendrite development GO:0016358 67 28 0,000 0,05893786 0,07578169 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05893786 0,07574182 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05893786 0,075702 ! sperm motility GO:0030317 37 28 0,000 0,05893786 0,07566222 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05893786 0,07562248 ! base-excision repair GO:0006284 41 28 0,000 0,05893786 0,07558278 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05893786 0,07554313 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05893786 0,07550352 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05893786 0,07546394 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05893786 0,07542441 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05893786 0,07538492 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05893786 0,07534548 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05893786 0,07530607 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05893786 0,0752667 ! lipid oxidation GO:0034440 48 28 0,000 0,05893786 0,07522738 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05893786 0,0751881 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05893786 0,07514885 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,06097812 0,07770973 ! translational initiation GO:0006413 66 29 0,000 0,06097812 0,07766921 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06097812 0,07762874 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06097812 0,07758831 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06097812 0,07754792 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,06097812 0,07750757 ! autophagy GO:0006914 47 29 0,000 0,06097812 0,07746727 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,06097812 0,077427 ! primary neural tube formation GO:0014020 61 29 0,000 0,06097812 0,07738678 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06097812 0,0773466 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06097812 0,07730646 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,06097812 0,07726637 ! somitogenesis GO:0001756 52 29 0,000 0,06097812 0,07722631 ! synaptogenesis GO:0007416 46 29 0,000 0,06097812 0,0771863 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06097812 0,07714632 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06097812 0,07710639 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06097812 0,0770665 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06097812 0,07702666 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06301401 0,07955723 ! phenol metabolic process GO:0018958 56 30 0,000 0,06301401 0,07951613 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,06301401 0,07947508 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06301401 0,07943407 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06301401 0,07939311 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06301401 0,07935218 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06301401 0,0793113 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06301401 0,07927046 ! acute-phase response GO:0006953 50 30 0,000 0,06301401 0,07922966 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06301401 0,07918891 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06301401 0,07914819 ! myofibril assembly GO:0030239 50 30 0,000 0,06301401 0,07910752 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06301401 0,07906689 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06301401 0,0790263 ! cell fate determination GO:0001709 64 30 0,000 0,06301401 0,07898575 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,06301401 0,07894525 ! phospholipid transport GO:0015914 65 30 0,000 0,06301401 0,07890479 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06301401 0,07886436 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06301401 0,07882398 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06301401 0,07878364 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06301401 0,07874334 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06301401 0,07870309 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,06301401 0,07866287 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06504555 0,08115744 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06504555 0,08111602 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06504555 0,08107463 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06504555 0,08103329 ! cell junction assembly GO:0034329 85 31 0,000 0,06504555 0,08099199 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06504555 0,08095073 ! ovulation cycle process GO:0022602 55 31 0,000 0,06504555 0,08090951 ! peptide transport GO:0015833 60 31 0,000 0,06504555 0,08086833 ! male gonad development GO:0008584 56 31 0,000 0,06504555 0,0808272 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06504555 0,08078611 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06504555 0,08074506 ! detection of light stimulus GO:0009583 44 31 0,000 0,06504555 0,08070405 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,06504555 0,08066308 ! natural killer cell activation GO:0030101 50 31 0,000 0,06504555 0,08062216 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06504555 0,08058128 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06504555 0,08054043 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06504555 0,08049963 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06504555 0,08045887 ! eye morphogenesis GO:0048592 65 31 0,000 0,06504555 0,08041816 ! response to heat GO:0009408 54 31 0,000 0,06504555 0,08037748 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06504555 0,08033684 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06707274 0,08279873 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06707274 0,08275692 ! collagen metabolic process GO:0032963 49 32 0,000 0,06707274 0,08271514 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06707274 0,08267341 ! spindle organization GO:0007051 50 32 0,000 0,06707274 0,08263172 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06707274 0,08259007 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06707274 0,08254846 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06707274 0,08250689 ! muscle cell development GO:0055001 52 32 0,000 0,06707274 0,08246537 ! mesoderm formation GO:0001707 73 32 0,000 0,06707274 0,08242389 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06707274 0,08238245 ! ovulation cycle GO:0042698 57 32 0,000 0,06707274 0,08234105 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06707274 0,08229969 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06707274 0,08225838 ! hindbrain development GO:0030902 65 32 0,000 0,06707274 0,08221711 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06707274 0,08217587 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,06707274 0,08213468 ! gene silencing GO:0016458 71 32 0,000 0,06707274 0,08209353 ! regulation of pH GO:0006885 56 33 0,000 0,06909558 0,08452705 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06909558 0,08448474 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06909558 0,08444248 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06909558 0,08440026 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06909558 0,08435808 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06909558 0,08431594 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06909558 0,08427385 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06909558 0,08423179 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06909558 0,08418978 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06909558 0,08414781 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06909558 0,08410589 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06909558 0,084064 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06909558 0,08402216 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,0711141 0,08643371 ! glial cell differentiation GO:0010001 67 34 0,000 0,0711141 0,08639073 ! post-embryonic development GO:0009791 76 34 0,000 0,0711141 0,08634779 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,0711141 0,0863049 ! spliceosome assembly GO:0000245 75 34 0,000 0,0711141 0,08626204 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,0711141 0,08621923 ! formation of primary germ layer GO:0001704 76 34 0,000 0,0711141 0,08617647 ! cell fate specification GO:0001708 56 34 0,000 0,0711141 0,08613374 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,0711141 0,08609106 ! adult locomotory behavior GO:0008344 62 34 0,000 0,0711141 0,08604842 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,0711141 0,08600582 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0731283 0,08839804 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0731283 0,08835432 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0731283 0,08831065 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,0731283 0,08826702 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0731283 0,08822343 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0731283 0,08817988 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0731283 0,08813638 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0731283 0,08809292 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0731283 0,0880495 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0731283 0,08800613 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,0731283 0,0879628 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0731283 0,08791951 ! telencephalon development GO:0021537 81 35 0,000 0,0731283 0,08787626 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0731283 0,08783306 ! placenta development GO:0001890 53 35 0,000 0,0731283 0,0877899 ! vesicle localization GO:0051648 70 35 0,000 0,0731283 0,08774678 ! regulation of muscle development GO:0048634 82 36 0,000 0,07513819 0,09011419 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07513819 0,09006997 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07513819 0,0900258 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07513819 0,08998167 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07513819 0,08993758 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07513819 0,08989354 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07513819 0,08984954 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07513819 0,08980558 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07513819 0,08976166 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,07513819 0,08971779 ! aerobic respiration GO:0009060 56 36 0,000 0,07513819 0,08967396 ! embryonic organ development GO:0048568 67 36 0,000 0,07513819 0,08963018 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07513819 0,08958643 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07513819 0,08954273 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07714378 0,09188798 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07714378 0,0918432 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07714378 0,09179846 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07714378 0,09175377 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07714378 0,09170912 ! odontogenesis GO:0042476 74 37 0,000 0,07714378 0,09166452 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07714378 0,09161996 ! cell junction organization GO:0034330 96 37 0,000 0,07714378 0,09157544 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07714378 0,09153096 ! female gonad development GO:0008585 71 37 0,000 0,07714378 0,09148653 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07714378 0,09144214 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07714378 0,09139779 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,07914507 0,09372342 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07914507 0,09367801 ! meiosis I GO:0007127 74 38 0,000 0,07914507 0,09363264 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07914507 0,09358732 ! organic anion transport GO:0015711 82 38 0,000 0,07914507 0,09354205 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07914507 0,09349681 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07914507 0,09345162 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07914507 0,09340648 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07914507 0,09336137 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07914507 0,09331632 ! regulation of protein stability GO:0031647 77 38 0,000 0,07914507 0,0932713 ! spermatid development GO:0007286 69 38 0,000 0,07914507 0,09322633 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07914507 0,0931814 ! pigment metabolic process GO:0042440 87 38 0,000 0,07914507 0,09313652 ! neural tube formation GO:0001841 79 38 0,000 0,07914507 0,09309167 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08114208 0,09539466 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08114208 0,09534877 ! negative regulation of binding GO:0051100 71 39 0,000 0,08114208 0,09530293 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,08114208 0,09525714 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08114208 0,09521138 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08114208 0,09516568 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,08114208 0,09512001 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08114208 0,09507439 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,08114208 0,09502881 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08114208 0,09498328 ! glucan metabolic process GO:0044042 64 39 0,000 0,08114208 0,09493779 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,08313482 0,09722276 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,08313482 0,09717625 ! learning GO:0007612 82 40 0,000 0,08313482 0,09712977 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,08313482 0,09708334 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,08313482 0,09703696 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,08313482 0,09699062 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,08313482 0,09694432 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08512328 0,09921574 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08512328 0,09916842 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08512328 0,09912116 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08512328 0,09907393 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08512328 0,09902675 ! gliogenesis GO:0042063 91 41 0,000 0,08512328 0,09897962 ! feeding behavior GO:0007631 69 41 0,000 0,08512328 0,09893253 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08512328 0,09888549 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,08512328 0,09883849 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08512328 0,09879154 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08512328 0,09874463 ! spermatid differentiation GO:0048515 73 41 0,000 0,08512328 0,09869776 ! RNA modification GO:0009451 64 41 0,000 0,08512328 0,09865094 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,0871075 0,10090262 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,0871075 0,10085479 ! T cell differentiation GO:0030217 93 42 0,000 0,0871075 0,10080702 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,0871075 0,10075929 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,0871075 0,1007116 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,0871075 0,10066396 ! regulation of protein secretion GO:0050708 77 42 0,000 0,0871075 0,10061637 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,0871075 0,10056882 ! cytokinesis GO:0000910 84 42 0,000 0,0871075 0,10052131 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,0871075 0,10047385 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,08908746 0,10270914 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08908746 0,10266069 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08908746 0,10261229 ! regulation of tube size GO:0035150 76 43 0,000 0,08908746 0,10256394 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,08908746 0,10251563 ! glucose transport GO:0015758 66 43 0,000 0,08908746 0,10246736 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,08908746 0,10241914 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08908746 0,10237097 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08908746 0,10232284 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08908746 0,10227475 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08908746 0,10222671 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,08908746 0,10217872 ! segmentation GO:0035282 78 43 0,000 0,08908746 0,10213077 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08908746 0,10208287 ! neuron migration GO:0001764 85 43 0,000 0,08908746 0,10203501 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,08908746 0,10198719 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,09106319 0,10420017 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,09106319 0,10415139 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,09106319 0,10410265 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,09106319 0,10405396 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,09106319 0,10400532 ! hexose transport GO:0008645 68 44 0,000 0,09106319 0,10395672 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,09106319 0,10390816 ! striated muscle contraction GO:0006941 85 44 0,000 0,09106319 0,10385965 ! phagocytosis GO:0006909 105 44 0,000 0,09106319 0,10381119 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,09106319 0,10376277 ! double-strand break repair GO:0006302 85 44 0,000 0,09106319 0,10371439 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,09303469 0,10591041 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,09303469 0,10586108 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,09303469 0,1058118 ! biopolymer methylation GO:0043414 91 45 0,000 0,09303469 0,10576256 ! B cell differentiation GO:0030183 124 45 0,000 0,09303469 0,10571337 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,09303469 0,10566422 ! female gamete generation GO:0007292 71 45 0,000 0,09303469 0,10561512 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,09303469 0,10556607 ! polyol metabolic process GO:0019751 77 45 0,000 0,09303469 0,10551706 ! developmental growth GO:0048589 88 45 0,000 0,09303469 0,10546809 ! maintenance of location in cell GO:0051651 101 45 0,000 0,09303469 0,10541917 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09500196 0,10759842 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09500196 0,10754856 ! glycolysis GO:0006096 71 46 0,000 0,09500196 0,10749875 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,09500196 0,10744898 ! leukocyte migration GO:0050900 75 46 0,000 0,09500196 0,10739926 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,09500196 0,10734958 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,09500196 0,10729995 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09500196 0,10725037 ! pigmentation GO:0043473 103 46 0,000 0,09500196 0,10720083 ! cell growth GO:0016049 90 46 0,000 0,09500196 0,10715134 ! neural tube development GO:0021915 91 47 0,000 0,09696503 0,10931498 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09892389 0,11147189 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09892389 0,1114205 ! mitochondrial transport GO:0006839 94 48 0,000 0,09892389 0,11136915 ! cellular component disassembly GO:0022411 89 48 0,000 0,09892389 0,11131785 ! endosome transport GO:0016197 127 48 0,000 0,09892389 0,1112666 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,09892389 0,1112154 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09892389 0,11116424 ! male sex differentiation GO:0046661 93 48 0,000 0,09892389 0,11111313 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09892389 0,11106207 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09892389 0,11101105 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09892389 0,11096008 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09892389 0,11090916 ! methylation GO:0032259 97 48 0,000 0,09892389 0,11085828 ! response to calcium ion GO:0051592 94 49 0,000 0,10087855 0,11299693 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,10087855 0,11294515 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,10087855 0,11289341 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,10087855 0,11284172 ! JNK cascade GO:0007254 106 49 0,000 0,10087855 0,11279007 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,10087855 0,11273848 ! regulation of action potential GO:0001508 102 50 0,000 0,10282904 0,11486572 ! regulation of ion transport GO:0043269 86 50 0,000 0,10282904 0,11481322 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,10282904 0,11476077 ! endocrine system development GO:0035270 109 50 0,000 0,10282904 0,11470837 ! activation of caspase activity GO:0006919 95 50 0,000 0,10282904 0,11465602 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,10282904 0,11460371 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10282904 0,11455145 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10282904 0,11449924 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10282904 0,11444708 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,10282904 0,11439496 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,10477534 0,11650713 ! viral infectious cycle GO:0019058 104 51 0,000 0,10477534 0,11645412 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,10477534 0,11640116 ! peptide metabolic process GO:0006518 80 51 0,000 0,10477534 0,11634825 ! response to temperature stimulus GO:0009266 84 51 0,000 0,10477534 0,11629539 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,10477534 0,11624258 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,10477534 0,11618981 ! positive regulation of binding GO:0051099 88 52 0,000 0,10671748 0,11828984 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,10671748 0,11823619 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,10671748 0,11818259 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,10671748 0,11812904 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,10671748 0,11807554 ! excretion GO:0007588 87 52 0,000 0,10671748 0,11802209 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,10671748 0,11796869 ! histone modification GO:0016570 104 52 0,000 0,10671748 0,11791533 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,10671748 0,11786203 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,10671748 0,11780877 ! amino acid activation GO:0043038 98 52 0,000 0,10671748 0,11775556 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10865546 0,11983986 ! positive regulation of growth GO:0045927 96 53 0,000 0,10865546 0,11978578 ! chromatin remodeling GO:0006338 122 53 0,000 0,10865546 0,11973175 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10865546 0,11967777 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10865546 0,11962383 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,10865546 0,11956995 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,10865546 0,11951611 ! cartilage development GO:0051216 99 53 0,000 0,10865546 0,11946232 ! synapse organization GO:0050808 102 53 0,000 0,10865546 0,11940859 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,11058929 0,12147915 ! regulation of translational initiation GO:0006446 87 54 0,000 0,11058929 0,12142455 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,11058929 0,12137 ! neuromuscular process GO:0050905 107 54 0,000 0,11058929 0,1213155 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,11058929 0,12126105 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,11058929 0,12120665 ! covalent chromatin modification GO:0016569 115 54 0,000 0,11058929 0,1211523 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,11058929 0,121098 ! regulation of cell shape GO:0008360 142 54 0,000 0,11058929 0,12104374 ! RNA catabolic process GO:0006401 103 55 0,000 0,11251898 0,1231007 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,11251898 0,12304559 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,11251898 0,12299054 ! cell recognition GO:0008037 98 55 0,000 0,11251898 0,12293554 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,11251898 0,12288058 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,11251898 0,12282567 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,11444453 0,12487181 ! glucose catabolic process GO:0006007 88 56 0,000 0,11444453 0,12481607 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,11444453 0,12476037 ! regulation of DNA replication GO:0006275 105 56 0,000 0,11444453 0,12470472 ! RNA elongation GO:0006354 90 56 0,000 0,11444453 0,12464913 ! chloride transport GO:0006821 102 57 0,000 0,11636596 0,1266854 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,11636596 0,12662897 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 0,000 0,11636596 0,12657259 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,11636596 0,12651626 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11828328 0,12854362 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,11828328 0,12848646 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11828328 0,12842936 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11828328 0,1283723 ! aging GO:0007568 112 58 0,000 0,11828328 0,1283153 ! gastrulation GO:0007369 122 58 0,000 0,11828328 0,12825835 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11828328 0,12820144 ! maintenance of location GO:0051235 124 58 0,000 0,11828328 0,12814459 ! nuclear export GO:0051168 110 59 0,000 0,12019649 0,13015959 ! establishment of organelle localization GO:0051656 122 59 0,000 0,12019649 0,13010192 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,1221056 0,13210983 ! DNA catabolic process GO:0006308 94 60 0,000 0,1221056 0,13205134 ! regulation of endocytosis GO:0030100 104 60 0,000 0,1221056 0,13199292 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,1221056 0,13193454 ! adult behavior GO:0030534 104 60 0,000 0,1221056 0,13187621 ! regulation of cellular component size GO:0032535 125 61 0,000 0,12401063 0,13387449 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,12401063 0,13381535 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,12401063 0,13375627 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,12401063 0,13369725 ! regulation of heart contraction GO:0008016 123 61 0,000 0,12401063 0,13363827 ! camera-type eye development GO:0043010 126 61 0,000 0,12401063 0,13357935 ! proton transport GO:0015992 117 61 0,000 0,12401063 0,13352048 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,12401063 0,13346166 ! viral reproductive process GO:0022415 132 62 0,000 0,12591157 0,13544781 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,12591157 0,13538819 ! tRNA processing GO:0008033 102 62 0,000 0,12591157 0,13532863 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,12591157 0,13526911 ! regulation of mitosis GO:0007088 112 63 0,000 0,12780844 0,1372466 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,12780844 0,1371863 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,12780844 0,13712605 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12780844 0,13706586 ! hydrogen transport GO:0006818 121 64 0,000 0,12970125 0,13903473 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12970125 0,13897375 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,13159001 0,14093572 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,13159001 0,14087396 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,13159001 0,14081226 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,13159001 0,14075061 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,13159001 0,14068901 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,13347471 0,14264161 ! gonad development GO:0008406 115 66 0,000 0,13347471 0,14257924 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,13535538 0,144525 ! activation of MAPK activity GO:0000187 124 67 0,000 0,13535538 0,14446186 ! chromosome segregation GO:0007059 127 67 0,000 0,13535538 0,14439878 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,13535538 0,14433575 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,13535538 0,14427278 ! secondary metabolic process GO:0019748 125 67 0,000 0,13535538 0,14420986 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,13535538 0,14414699 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,13723203 0,14608185 ! hexose catabolic process GO:0019320 113 68 0,000 0,13723203 0,14601822 ! extracellular matrix organization GO:0030198 146 68 0,000 0,13723203 0,14595465 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,13723203 0,14589114 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,13723203 0,14582768 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,13723203 0,14576428 ! viral reproduction GO:0016032 142 68 0,000 0,13723203 0,14570093 ! adaptive immune response GO:0002250 126 68 0,000 0,13723203 0,14563764 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,13723203 0,1455744 ! cell projection assembly GO:0030031 138 68 0,000 0,13723203 0,14551122 ! negative regulation of cell size GO:0045792 144 69 0,000 0,13910465 0,14743282 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13910465 0,14736889 ! lung development GO:0030324 165 69 0,000 0,13910465 0,14730501 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13910465 0,14724119 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,13910465 0,14717742 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13910465 0,1471137 ! single fertilization GO:0007338 83 69 0,000 0,13910465 0,14705005 ! cell redox homeostasis GO:0045454 114 70 0,000 0,14097326 0,14896093 ! germ cell development GO:0007281 133 70 0,000 0,14097326 0,14889653 ! activation of immune response GO:0002253 120 70 0,000 0,14097326 0,14883218 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,14097326 0,14876789 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,14283787 0,15067051 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,14283787 0,15060548 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,14283787 0,15054051 ! carbohydrate transport GO:0008643 114 72 0,000 0,14469848 0,1524357 ! respiratory tube development GO:0030323 171 72 0,000 0,14469848 0,15236999 ! actin filament organization GO:0007015 167 72 0,000 0,14469848 0,15230434 ! B cell activation GO:0042113 179 72 0,000 0,14469848 0,15223875 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,14469848 0,15217322 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,14469848 0,15210774 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,14469848 0,15204231 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,14469848 0,15197695 ! humoral immune response GO:0006959 115 73 0,000 0,1465551 0,15386082 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,1465551 0,15379472 ! regulation of immune effector process GO:0002697 156 73 0,000 0,1465551 0,15372869 ! acute inflammatory response GO:0002526 118 74 0,000 0,14840775 0,15560521 ! amino acid transport GO:0006865 148 74 0,000 0,14840775 0,15553845 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,14840775 0,15547176 ! respiratory system development GO:0060541 175 74 0,000 0,14840775 0,15540512 ! organelle localization GO:0051640 155 74 0,000 0,14840775 0,15533853 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,15025643 0,15720619 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,15025643 0,15713889 ! reproductive structure development GO:0048608 131 75 0,000 0,15025643 0,15707165 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,15025643 0,15700447 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,15025643 0,15693735 ! eye development GO:0001654 155 75 0,000 0,15025643 0,15687028 ! axon guidance GO:0007411 162 75 0,000 0,15025643 0,15680327 ! rhythmic process GO:0048511 142 75 0,000 0,15025643 0,15673632 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,15210115 0,15859287 ! learning or memory GO:0007611 161 76 0,000 0,15210115 0,15852521 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,15210115 0,15845761 ! regulation of blood pressure GO:0008217 134 76 0,000 0,15210115 0,15839007 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,15210115 0,15832258 ! amine catabolic process GO:0009310 136 77 0,000 0,15394191 0,16017039 ! neurotransmitter transport GO:0006836 142 77 0,000 0,15394191 0,16010221 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,15394191 0,16003408 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,15394191 0,15996601 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,15394191 0,15989799 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,15394191 0,15983004 ! regulation of catabolic process GO:0009894 173 77 0,000 0,15394191 0,15976214 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,15577873 0,16159976 ! antigen processing and presentation GO:0019882 117 78 0,000 0,15577873 0,16153117 ! fertilization GO:0009566 99 78 0,000 0,15577873 0,16146264 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,15577873 0,16139416 ! blood coagulation GO:0007596 151 79 0,000 0,15761161 0,16322389 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,15761161 0,16315473 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,15761161 0,16308563 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,15761161 0,16301658 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,15761161 0,1629476 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,15761161 0,16287867 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,15944057 0,16469907 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,15944057 0,16462946 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,15944057 0,16455991 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,15944057 0,16449042 ! meiosis GO:0007126 143 81 0,000 0,1612656 0,16630303 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,1612656 0,16623286 ! protein import into nucleus GO:0006606 174 82 0,000 0,16308673 0,16803917 ! meiotic cell cycle GO:0051321 144 82 0,000 0,16308673 0,16796833 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,16490395 0,16976837 ! exocytosis GO:0006887 153 83 0,000 0,16490395 0,16969686 ! response to drug GO:0042493 149 83 0,000 0,16490395 0,16962541 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,16490395 0,16955402 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,16490395 0,16948269 ! nuclear import GO:0051170 177 83 0,000 0,16490395 0,16941142 ! inorganic anion transport GO:0015698 156 83 0,000 0,16490395 0,16934021 ! response to metal ion GO:0010038 158 84 0,000 0,16671728 0,17113038 ! T cell activation GO:0042110 189 84 0,000 0,16671728 0,17105851 ! response to nutrient GO:0007584 135 84 0,000 0,16671728 0,17098669 ! digestion GO:0007586 130 84 0,000 0,16671728 0,17091494 ! regulation of ligase activity GO:0051340 147 84 0,000 0,16671728 0,17084325 ! hemostasis GO:0007599 165 85 0,000 0,16852672 0,17262506 ! negative regulation of transport GO:0051051 164 85 0,000 0,16852672 0,17255271 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,16852672 0,17248042 ! negative regulation of growth GO:0045926 168 85 0,000 0,16852672 0,1724082 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,16852672 0,17233603 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,16852672 0,17226392 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,16852672 0,17219187 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,17033228 0,17396395 ! regulation of lyase activity GO:0051339 169 86 0,000 0,17033228 0,17389125 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,17033228 0,17381861 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,17213397 0,17558384 ! mitochondrion organization GO:0007005 159 87 0,000 0,17213397 0,17551056 ! alcohol catabolic process GO:0046164 142 87 0,000 0,17213397 0,17543734 ! nucleosome assembly GO:0006334 126 87 0,000 0,17213397 0,17536418 ! cellular respiration GO:0045333 143 88 0,000 0,1739318 0,17712188 ! amine biosynthetic process GO:0009309 146 88 0,000 0,1739318 0,17704808 ! sensory perception of smell GO:0007608 117 88 0,000 0,1739318 0,17697434 ! chromatin assembly GO:0031497 128 88 0,000 0,1739318 0,17690066 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,1739318 0,17682705 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,17572578 0,17857657 ! regulation of DNA binding GO:0051101 167 89 0,000 0,17572578 0,17850232 ! cellular defense response GO:0006968 123 89 0,000 0,17572578 0,17842813 ! protein localization in nucleus GO:0034504 192 89 0,000 0,17572578 0,178354 ! regulation of neurological system process GO:0031644 175 89 0,000 0,17572578 0,17827993 ! response to inorganic substance GO:0010035 173 90 0,000 0,17751591 0,18002133 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,17751591 0,17994663 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,17751591 0,17987199 ! response to unfolded protein GO:0006986 139 90 0,000 0,17751591 0,17979742 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,17751591 0,17972291 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,17930221 0,18145621 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,17930221 0,18138107 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,18108467 0,18310838 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,18108467 0,18303262 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,18286332 0,18475396 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,18286332 0,18467759 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,18286332 0,18460127 ! vitamin metabolic process GO:0006766 153 93 0,000 0,18286332 0,18452502 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,18463815 0,18623905 ! female pregnancy GO:0007565 166 94 0,000 0,18463815 0,18616219 ! sterol metabolic process GO:0016125 166 94 0,000 0,18463815 0,18608539 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,18463815 0,18600866 ! regulation of defense response GO:0031347 171 95 0,000 0,18640917 0,18771542 ! nucleosome organization GO:0034728 143 95 0,000 0,18640917 0,18763807 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,18640917 0,18756079 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,18640917 0,18748358 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,18640917 0,18740642 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,18640917 0,18732933 ! sex differentiation GO:0007548 171 96 0,000 0,1881764 0,18902753 ! response to protein stimulus GO:0051789 158 96 0,000 0,1881764 0,18894983 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1881764 0,1888722 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,18993984 0,19056387 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,18993984 0,19048564 ! transcription initiation GO:0006352 171 97 0,000 0,18993984 0,19040748 ! leukocyte differentiation GO:0002521 232 98 0,000 0,1916995 0,19209265 ! forebrain development GO:0030900 210 98 0,000 0,1916995 0,19201389 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,1916995 0,1919352 ! mRNA transport GO:0051028 185 100 0,000 0,19520751 0,19536745 ! positive regulation of immune response GO:0050778 175 100 0,000 0,19520751 0,19528744 ! hormone metabolic process GO:0042445 171 100 0,000 0,19520751 0,19520751