pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/733-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 9,932E-10 2,39E-06 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 2,000 6,648E-08 7,997E-05 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! mesoderm formation GO:0001707 69 31 3,000 1,454E-07 1,166E-04 ! formation of primary germ layer GO:0001704 72 33 3,000 1,886E-07 1,135E-04 ! mesoderm morphogenesis GO:0048332 76 34 3,000 2,135E-07 1,028E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,498E-06 6,006E-04 ! gastrulation GO:0007369 112 55 3,000 1,534E-06 5,273E-04 ! mesoderm development GO:0007498 119 61 3,000 2,332E-06 7,012E-04 ! paraxial mesoderm development GO:0048339 14 5 1,000 2,276E-05 6,083E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 2,000 2,298E-05 5,529E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 2,298E-05 5,027E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 3,167E-05 6,349E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! interaction with symbiont GO:0051702 13 6 1,000 3,41E-05 6,311E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,769E-05 8,197E-03 ! ER overload response GO:0006983 12 8 1,000 6,353E-05 0,01019025 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 6,353E-05 9,553E-03 ! mitochondrion localization GO:0051646 15 9 1,000 8,16E-05 0,01154912 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,019E-04 0,0136211 ! midbrain development GO:0030901 13 10 1,000 1,019E-04 0,0129042 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,019E-04 0,01225899 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 1,242E-04 0,0142277 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,244E-04 0,01360785 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 1,363E-04 0,01425837 GO:0035113|embryonic appendage morphogenesis, ! hippocampus development GO:0021766 26 12 1,000 1,492E-04 0,01495406 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,559E-04 0,01500236 ! appendage morphogenesis GO:0035107 135 70 2,000 1,699E-04 0,01572268 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 2,000 1,772E-04 0,01579144 GO:0060173|limb development, ! cofactor transport GO:0051181 26 14 1,000 2,053E-04 0,01763861 ! cell killing GO:0001906 29 15 1,000 2,366E-04 0,01963132 ! limbic system development GO:0021761 36 17 1,000 3,059E-04 0,02453186 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 3,438E-04 0,0266821 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 3,438E-04 0,02584828 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 3,438E-04 0,025065 ! forebrain development GO:0030900 188 95 2,000 4,183E-04 0,02960111 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 4,261E-04 0,02929077 ! cellular response to starvation GO:0009267 33 20 1,000 4,261E-04 0,02847713 ! peptidyl-serine modification GO:0018209 43 20 1,000 4,261E-04 0,02770748 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 4,705E-04 0,02978917 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 4,705E-04 0,02902534 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 5,17E-04 0,03109941 ! pallium development GO:0021543 49 24 1,000 6,166E-04 0,03618101 ! response to starvation GO:0042594 42 25 1,000 6,695E-04 0,03835351 ! osteoblast differentiation GO:0001649 60 25 1,000 6,695E-04 0,03746157 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 6,695E-04 0,03661017 ! interaction with host GO:0051701 62 25 1,000 6,695E-04 0,03579661 ! somitogenesis GO:0001756 43 25 1,000 6,695E-04 0,03501842 ! cellular response to nutrient levels GO:0031669 41 25 1,000 6,695E-04 0,03427335 ! embryonic pattern specification GO:0009880 44 26 1,000 7,246E-04 0,0363206 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 7,246E-04 0,03557936 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 7,246E-04 0,03486777 ! iron ion transport GO:0006826 59 27 1,000 7,818E-04 0,03688294 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 8,411E-04 0,03891839 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 9,026E-04 0,04097269 ! complement activation, classical pathway GO:0006958 48 29 1,000 9,026E-04 0,04021393 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 9,026E-04 0,03948277 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 1,032E-03 0,04432666 ! iron ion homeostasis GO:0055072 54 31 1,000 1,032E-03 0,043549 ! BMP signaling pathway GO:0030509 64 32 1,000 1,099E-03 0,04560702 ! hindbrain development GO:0030902 61 32 1,000 1,099E-03 0,04483402 ! cell fate specification GO:0001708 52 33 1,000 1,169E-03 0,04688552 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 1,241E-03 0,04895163 ! placenta development GO:0001890 53 34 1,000 1,241E-03 0,04816209 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 1,241E-03 0,04739761 ! regulation of muscle development GO:0048634 70 35 1,000 1,315E-03 0,04943667 ! odontogenesis GO:0042476 66 35 1,000 1,315E-03 0,04867611 ! telencephalon development GO:0021537 68 35 1,000 1,315E-03 0,04793859 ! glycogen metabolic process GO:0005977 61 37 1,000 1,469E-03 0,05275553 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 1,549E-03 0,05481421 GO:0006956|complement activation, ! glucan metabolic process GO:0044042 62 38 1,000 1,549E-03 0,0540198 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 1,631E-03 0,05607189 ! segmentation GO:0035282 67 39 1,000 1,631E-03 0,05528214 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 1,89E-03 0,06315834 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 1,98E-03 0,06526846 ! energy reserve metabolic process GO:0006112 74 43 1,000 1,98E-03 0,06438645 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 2,073E-03 0,06648854 ! maintenance of location in cell GO:0051651 97 44 1,000 2,073E-03 0,06561369 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 2,263E-03 0,07071697 ! positive regulation of protein transport GO:0051222 72 46 1,000 2,263E-03 0,06981034 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 2,564E-03 0,07808905 GO:0019724|B cell mediated immunity, ! regulation of ossification GO:0030278 117 50 1,000 2,668E-03 0,08024809 ! chloride transport GO:0006821 90 55 1,000 3,219E-03 0,09561461 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 3,219E-03 0,09444858 ! regulation of bone remodeling GO:0046850 137 57 1,000 3,453E-03 0,10009114 ! regulation of intracellular transport GO:0032386 101 57 1,000 3,453E-03 0,09889957 ! maintenance of location GO:0051235 118 57 1,000 3,453E-03 0,09773605 ! regulation of tissue remodeling GO:0034103 140 58 1,000 3,573E-03 0,09995264 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 4,332E-03 0,11980263 ! adaptive immune response GO:0002250 119 67 1,000 4,737E-03 0,12952074 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 4,737E-03 0,12806545 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 4,876E-03 0,13035387 ! humoral immune response GO:0006959 109 71 1,000 5,304E-03 0,14022853 ! acute inflammatory response GO:0002526 113 72 1,000 5,45E-03 0,14252927 ! transition metal ion transport GO:0000041 126 74 1,000 5,748E-03 0,14870723 ! leukocyte mediated immunity GO:0002443 128 74 1,000 5,748E-03 0,14712524 ! organelle localization GO:0051640 136 74 1,000 5,748E-03 0,14557655 ! blood coagulation GO:0007596 146 78 1,000 6,366E-03 0,15954892 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 6,525E-03 0,16184887 ! inorganic anion transport GO:0015698 138 80 1,000 6,686E-03 0,16414615 ! hemostasis GO:0007599 158 84 1,000 7,347E-03 0,17855919 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 7,614E-03 0,1831951 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,614E-03 0,18138128 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,614E-03 0,17960303 ! positive regulation of helicase activity GO:0051096 11 5 0,000 7,614E-03 0,17785932 ! neuron fate determination GO:0048664 7 5 0,000 7,614E-03 0,17614913 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,614E-03 0,17447152 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 7,614E-03 0,17282556 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,614E-03 0,17121037 ! polyol transport GO:0015791 12 5 0,000 7,614E-03 0,16962509 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 7,614E-03 0,16806889 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,614E-03 0,166541 ! response to superoxide GO:0000303 10 5 0,000 7,614E-03 0,16504063 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,614E-03 0,16356705 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 7,614E-03 0,16211955 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 7,614E-03 0,16069745 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,614E-03 0,15930008 ! female meiosis GO:0007143 7 5 0,000 7,614E-03 0,15792681 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 7,614E-03 0,156577 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,614E-03 0,15525008 ! cobalt ion transport GO:0006824 11 5 0,000 7,614E-03 0,15394546 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 7,614E-03 0,15266258 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 7,614E-03 0,15140091 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 7,614E-03 0,15015991 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,614E-03 0,1489391 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,614E-03 0,14773798 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 7,614E-03 0,14655608 ! embryonic camera-type eye development GO:0031076 10 5 0,000 7,614E-03 0,14539293 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,614E-03 0,14424811 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 7,614E-03 0,14312117 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 7,614E-03 0,1420117 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,614E-03 0,1409193 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,614E-03 0,13984358 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,614E-03 0,13878416 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 7,614E-03 0,13774067 ! negative chemotaxis GO:0050919 14 5 0,000 7,614E-03 0,13671276 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,614E-03 0,13570007 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,614E-03 0,13470228 ! sensory perception of bitter taste GO:0050913 7 5 0,000 7,614E-03 0,13371905 ! behavioral response to pain GO:0048266 9 5 0,000 7,614E-03 0,13275007 ! clathrin coat assembly GO:0048268 14 5 0,000 7,614E-03 0,13179503 ! Notch receptor processing GO:0007220 8 5 0,000 7,614E-03 0,13085364 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,614E-03 0,1299256 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,614E-03 0,12901063 ! micturition GO:0060073 9 5 0,000 7,614E-03 0,12810846 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,614E-03 0,12721882 ! copulation GO:0007620 9 5 0,000 7,614E-03 0,12634145 ! glial cell fate commitment GO:0021781 13 5 0,000 7,614E-03 0,12547609 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,614E-03 0,12462251 ! spermidine metabolic process GO:0008216 7 5 0,000 7,614E-03 0,12378047 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,614E-03 0,12294973 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,614E-03 0,12213006 ! apoptotic cell clearance GO:0043277 20 5 0,000 7,614E-03 0,12132126 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,614E-03 0,12052309 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,614E-03 0,11973536 ! grooming behavior GO:0007625 6 5 0,000 7,614E-03 0,11895785 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,614E-03 0,11819038 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 7,614E-03 0,11743275 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,614E-03 0,11668477 ! response to protozoan GO:0001562 10 5 0,000 7,614E-03 0,11594626 ! positive regulation of glycolysis GO:0045821 14 5 0,000 7,614E-03 0,11521704 ! lymph vessel development GO:0001945 10 5 0,000 7,614E-03 0,11449693 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 7,614E-03 0,11378577 ! endochondral ossification GO:0001958 16 5 0,000 7,614E-03 0,11308339 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,614E-03 0,11238963 ! parathyroid gland development GO:0060017 13 5 0,000 7,614E-03 0,11170433 ! anagen GO:0042640 6 5 0,000 7,614E-03 0,11102733 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,614E-03 0,11035849 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,614E-03 0,10969766 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 7,614E-03 0,1090447 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 7,614E-03 0,10839946 ! dorsal spinal cord development GO:0021516 7 5 0,000 7,614E-03 0,10776182 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 7,614E-03 0,10713163 ! sphingoid catabolic process GO:0046521 6 5 0,000 7,614E-03 0,10650878 ! skeletal myofibril assembly GO:0014866 10 5 0,000 7,614E-03 0,10589312 ! smooth muscle tissue development GO:0048745 28 5 0,000 7,614E-03 0,10528454 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,614E-03 0,10468291 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,614E-03 0,10408812 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,614E-03 0,10350005 ! cardiac muscle fiber development GO:0048739 10 5 0,000 7,614E-03 0,10291859 ! transepithelial chloride transport GO:0030321 9 5 0,000 7,614E-03 0,10234363 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,614E-03 0,10177505 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 7,614E-03 0,10121276 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 7,614E-03 0,10065665 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,614E-03 0,10010661 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,614E-03 0,09956255 ! histidine catabolic process GO:0006548 6 5 0,000 7,614E-03 0,09902438 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 7,614E-03 0,09849199 ! microvillus organization GO:0032528 7 5 0,000 7,614E-03 0,09796529 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 7,614E-03 0,0974442 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,614E-03 0,09692862 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,614E-03 0,09641847 ! tryptophan metabolic process GO:0006568 9 5 0,000 7,614E-03 0,09591366 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 7,614E-03 0,09541411 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,614E-03 0,09491974 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 7,614E-03 0,09443046 ! polyol catabolic process GO:0046174 7 5 0,000 7,614E-03 0,0939462 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,614E-03 0,09346689 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,614E-03 0,09299243 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,614E-03 0,09252278 ! muscle cell migration GO:0014812 8 5 0,000 7,614E-03 0,09205784 ! mitochondrial fission GO:0000266 8 5 0,000 7,614E-03 0,09159755 ! sister chromatid cohesion GO:0007062 12 5 0,000 7,614E-03 0,09114184 ! mRNA transcription GO:0009299 9 5 0,000 7,614E-03 0,09069064 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 7,614E-03 0,09024389 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 7,614E-03 0,08980152 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 7,614E-03 0,08936346 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,614E-03 0,08892966 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,614E-03 0,08850005 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,614E-03 0,08807457 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,614E-03 0,08765316 ! response to food GO:0032094 6 5 0,000 7,614E-03 0,08723576 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,614E-03 0,08682232 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,614E-03 0,08641278 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 7,614E-03 0,08600709 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,614E-03 0,08560518 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 7,614E-03 0,08520702 ! forebrain neuron development GO:0021884 13 5 0,000 7,614E-03 0,08481254 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,614E-03 0,0844217 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 7,614E-03 0,08403445 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,614E-03 0,08365073 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,614E-03 0,0832705 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,614E-03 0,08289371 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 7,614E-03 0,08252031 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,614E-03 0,08215027 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 7,614E-03 0,08178352 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 7,614E-03 0,08142004 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 7,614E-03 0,08105978 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 7,614E-03 0,08070269 ! basic amino acid transport GO:0015802 11 5 0,000 7,614E-03 0,08034873 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,614E-03 0,07999786 ! early endosome to late endosome transport GO:0045022 12 5 0,000 7,614E-03 0,07965004 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,614E-03 0,07930524 ! depyrimidination GO:0045008 10 5 0,000 7,614E-03 0,0789634 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,614E-03 0,0786245 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,614E-03 0,0782885 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,614E-03 0,07795536 ! zinc ion homeostasis GO:0055069 8 5 0,000 7,614E-03 0,07762504 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 7,614E-03 0,07729751 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 7,614E-03 0,07697273 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,614E-03 0,07665067 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,614E-03 0,07633129 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,614E-03 0,07601456 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 7,614E-03 0,07570045 ! peptidyl-arginine modification GO:0018195 9 5 0,000 7,614E-03 0,07538893 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,614E-03 0,07507996 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,614E-03 0,07477351 ! response to arsenic GO:0046685 10 5 0,000 7,614E-03 0,07446955 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,614E-03 0,07416805 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,614E-03 0,07386899 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 7,614E-03 0,07357233 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 7,614E-03 0,07327804 ! response to cadmium ion GO:0046686 7 5 0,000 7,614E-03 0,07298609 ! bile acid biosynthetic process GO:0006699 6 5 0,000 7,614E-03 0,07269647 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 7,614E-03 0,07240913 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,614E-03 0,07212405 ! decidualization GO:0046697 11 5 0,000 7,614E-03 0,07184121 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 7,614E-03 0,07156058 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 7,614E-03 0,07128214 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,614E-03 0,07100585 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,614E-03 0,0707317 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 7,614E-03 0,07045965 ! base conversion or substitution editing GO:0016553 5 5 0,000 7,614E-03 0,07018969 ! neural tube patterning GO:0021532 7 5 0,000 7,614E-03 0,06992179 ! embryonic cleavage GO:0040016 6 5 0,000 7,614E-03 0,06965593 ! peroxisome fission GO:0016559 5 5 0,000 7,614E-03 0,06939208 ! histone demethylation GO:0016577 10 5 0,000 7,614E-03 0,06913022 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 7,614E-03 0,06887034 ! mitotic recombination GO:0006312 9 5 0,000 7,614E-03 0,0686124 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,614E-03 0,06835638 ! metaphase plate congression GO:0051310 7 5 0,000 7,614E-03 0,06810227 ! regulation of sterol transport GO:0032371 7 5 0,000 7,614E-03 0,06785004 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,614E-03 0,06759967 ! enteric nervous system development GO:0048484 8 5 0,000 7,614E-03 0,06735114 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 7,614E-03 0,06710443 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 7,614E-03 0,06685952 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 7,614E-03 0,0666164 ! muscle cell proliferation GO:0033002 11 5 0,000 7,614E-03 0,06637503 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,614E-03 0,06613541 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 7,614E-03 0,06589752 ! plasminogen activation GO:0031639 5 5 0,000 7,614E-03 0,06566132 ! B cell homeostasis GO:0001782 13 5 0,000 7,614E-03 0,06542682 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,614E-03 0,06519398 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,614E-03 0,0649628 ! metaphase GO:0051323 8 5 0,000 7,614E-03 0,06473325 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 7,614E-03 0,06450532 ! cellular response to nutrient GO:0031670 8 5 0,000 7,614E-03 0,06427898 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,614E-03 0,06405423 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,614E-03 0,06383104 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,614E-03 0,06360941 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 7,614E-03 0,06338931 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 7,614E-03 0,06317072 ! response to redox state GO:0051775 5 5 0,000 7,614E-03 0,06295364 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 7,614E-03 0,06273805 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 7,614E-03 0,06252392 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,614E-03 0,06231126 ! regulation of telomerase activity GO:0051972 6 5 0,000 7,614E-03 0,06210003 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,614E-03 0,06189023 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 7,614E-03 0,06168185 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,614E-03 0,06147486 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 7,614E-03 0,06126926 ! striatum development GO:0021756 9 5 0,000 7,614E-03 0,06106503 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 7,614E-03 0,06086216 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 7,614E-03 0,06066063 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,614E-03 0,06046043 ! glial cell migration GO:0008347 11 5 0,000 7,614E-03 0,06026154 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,614E-03 0,06006397 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 7,614E-03 0,05986768 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 7,614E-03 0,05967267 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,614E-03 0,05947893 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,614E-03 0,05928644 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,614E-03 0,05909519 ! neuroprotection GO:0043526 6 5 0,000 7,614E-03 0,05890518 ! neural plate development GO:0001840 8 5 0,000 7,614E-03 0,05871638 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,614E-03 0,05852878 ! regulation of sensory perception GO:0051931 7 5 0,000 7,614E-03 0,05834239 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,614E-03 0,05815717 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,614E-03 0,05797313 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 7,614E-03 0,05779025 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 7,614E-03 0,05760852 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,614E-03 0,05742793 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,614E-03 0,05724847 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,614E-03 0,05707012 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,614E-03 0,05689289 ! spindle assembly GO:0051225 6 5 0,000 7,614E-03 0,05671675 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 7,614E-03 0,0565417 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,614E-03 0,05636772 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,614E-03 0,05619481 ! drug metabolic process GO:0017144 6 5 0,000 7,614E-03 0,05602296 ! stem cell division GO:0017145 11 5 0,000 7,614E-03 0,05585216 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,614E-03 0,0556824 ! organ regeneration GO:0031100 7 5 0,000 7,614E-03 0,05551367 ! carnitine metabolic process GO:0009437 7 5 0,000 7,614E-03 0,05534595 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 7,614E-03 0,05517925 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,614E-03 0,05501354 ! regulation of protein transport GO:0051223 154 87 1,000 7,862E-03 0,05663331 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 206 88 1,000 8,037E-03 0,05772157 ! ossification GO:0001503 188 90 1,000 8,392E-03 0,06009455 ! bone development GO:0060348 189 91 1,000 8,573E-03 0,0612035 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,13E-03 0,06499113 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,13E-03 0,06479942 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 9,13E-03 0,06460883 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,13E-03 0,06441936 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,13E-03 0,064231 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 9,13E-03 0,06404374 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 9,13E-03 0,06385756 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,13E-03 0,06367247 ! sleep GO:0030431 13 6 0,000 9,13E-03 0,06348845 ! response to oxygen radical GO:0000305 11 6 0,000 9,13E-03 0,06330548 ! positive regulation of axon extension GO:0045773 11 6 0,000 9,13E-03 0,06312357 ! myoblast cell fate commitment GO:0048625 16 6 0,000 9,13E-03 0,0629427 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 9,13E-03 0,06276286 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 9,13E-03 0,06258405 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,13E-03 0,06240626 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,13E-03 0,06222947 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 9,13E-03 0,06205368 ! forebrain regionalization GO:0021871 8 6 0,000 9,13E-03 0,06187888 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,13E-03 0,06170506 ! male meiosis GO:0007140 7 6 0,000 9,13E-03 0,06153222 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,13E-03 0,06136034 ! response to zinc ion GO:0010043 9 6 0,000 9,13E-03 0,06118942 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,13E-03 0,06101945 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 9,13E-03 0,06085042 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 9,13E-03 0,06068233 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,13E-03 0,06051516 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,13E-03 0,06034891 ! malate metabolic process GO:0006108 11 6 0,000 9,13E-03 0,06018357 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 9,13E-03 0,06001913 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 9,13E-03 0,05985559 ! protein refolding GO:0042026 15 6 0,000 9,13E-03 0,05969294 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,13E-03 0,05953117 ! opsonization GO:0008228 8 6 0,000 9,13E-03 0,05937028 ! mating behavior GO:0007617 7 6 0,000 9,13E-03 0,05921025 ! neuron remodeling GO:0016322 15 6 0,000 9,13E-03 0,05905108 ! erythrocyte maturation GO:0043249 7 6 0,000 9,13E-03 0,05889277 ! embryonic hemopoiesis GO:0035162 14 6 0,000 9,13E-03 0,0587353 ! equilibrioception GO:0050957 14 6 0,000 9,13E-03 0,05857867 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,13E-03 0,05842288 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 9,13E-03 0,05826791 ! photoreceptor cell development GO:0042461 10 6 0,000 9,13E-03 0,05811376 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,13E-03 0,05796043 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,13E-03 0,0578079 ! response to interferon-gamma GO:0034341 15 6 0,000 9,13E-03 0,05765617 ! toxin metabolic process GO:0009404 11 6 0,000 9,13E-03 0,05750524 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,13E-03 0,0573551 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,13E-03 0,05720574 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 9,13E-03 0,05705715 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 9,13E-03 0,05690933 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 9,13E-03 0,05676228 ! cGMP-mediated signaling GO:0019934 13 6 0,000 9,13E-03 0,05661599 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,13E-03 0,05647044 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 9,13E-03 0,05632565 ! thymic T cell selection GO:0045061 12 6 0,000 9,13E-03 0,05618159 ! protein lipoylation GO:0009249 10 6 0,000 9,13E-03 0,05603827 ! cysteine metabolic process GO:0006534 10 6 0,000 9,13E-03 0,05589568 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,13E-03 0,05575381 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,13E-03 0,05561266 ! glutamate catabolic process GO:0006538 10 6 0,000 9,13E-03 0,05547223 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 9,13E-03 0,0553325 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 9,13E-03 0,05519347 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 9,13E-03 0,05505514 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,13E-03 0,05491751 ! hyperosmotic response GO:0006972 9 6 0,000 9,13E-03 0,05478055 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 9,13E-03 0,05464428 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 9,13E-03 0,05450869 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,13E-03 0,05437377 ! urea metabolic process GO:0019627 7 6 0,000 9,13E-03 0,05423951 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,13E-03 0,05410592 ! neutrophil activation GO:0042119 8 6 0,000 9,13E-03 0,05397298 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,13E-03 0,05384069 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 9,13E-03 0,05370905 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,13E-03 0,05357805 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,13E-03 0,05344769 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,13E-03 0,05331797 ! neuron apoptosis GO:0051402 9 6 0,000 9,13E-03 0,05318887 ! nucleoside salvage GO:0043174 9 6 0,000 9,13E-03 0,05306039 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 9,13E-03 0,05293254 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,13E-03 0,05280529 ! T cell mediated immunity GO:0002456 16 6 0,000 9,13E-03 0,05267866 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,13E-03 0,05255264 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 9,13E-03 0,05242721 ! carnitine transport GO:0015879 10 6 0,000 9,13E-03 0,05230239 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 9,13E-03 0,05217815 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,13E-03 0,05205451 ! positive regulation of exocytosis GO:0045921 8 6 0,000 9,13E-03 0,05193145 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 9,13E-03 0,05180897 ! 5S class rRNA transcription GO:0042791 11 6 0,000 9,13E-03 0,05168706 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,13E-03 0,05156573 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 9,13E-03 0,05144497 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 9,13E-03 0,05132477 ! sodium ion homeostasis GO:0055078 11 6 0,000 9,13E-03 0,05120513 ! establishment of spindle localization GO:0051293 12 6 0,000 9,13E-03 0,05108605 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,13E-03 0,05096752 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,13E-03 0,05084954 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 9,13E-03 0,05073211 ! neural nucleus development GO:0048857 14 6 0,000 9,13E-03 0,05061521 ! response to UV-C GO:0010225 11 6 0,000 9,13E-03 0,05049886 ! astrocyte development GO:0014002 15 6 0,000 9,13E-03 0,05038303 ! protein targeting to lysosome GO:0006622 10 6 0,000 9,13E-03 0,05026774 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,13E-03 0,05015297 ! regulation of dendrite development GO:0050773 16 6 0,000 9,13E-03 0,05003873 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,13E-03 0,04992501 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 9,13E-03 0,0498118 ! response to copper ion GO:0046688 10 6 0,000 9,13E-03 0,0496991 ! response to exogenous dsRNA GO:0043330 10 6 0,000 9,13E-03 0,04958691 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 9,13E-03 0,04947523 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,13E-03 0,04936405 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,13E-03 0,04925337 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,13E-03 0,04914318 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 9,13E-03 0,04903349 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,13E-03 0,04892428 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,13E-03 0,04881556 ! hair follicle maturation GO:0048820 7 6 0,000 9,13E-03 0,04870732 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,13E-03 0,04859956 ! Schwann cell development GO:0014044 15 6 0,000 9,13E-03 0,04849228 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,13E-03 0,04838547 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,13E-03 0,04827913 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 9,13E-03 0,04817325 ! subpallium development GO:0021544 10 6 0,000 9,13E-03 0,04806784 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 9,13E-03 0,04796289 ! histone ubiquitination GO:0016574 8 6 0,000 9,13E-03 0,04785839 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 9,13E-03 0,04775435 ! maintenance of organ identity GO:0048496 9 6 0,000 9,13E-03 0,04765076 ! G2 phase GO:0051319 16 6 0,000 9,13E-03 0,04754762 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 9,13E-03 0,04744493 ! establishment of planar polarity GO:0001736 7 6 0,000 9,13E-03 0,04734268 ! regulation of mast cell activation GO:0033003 12 6 0,000 9,13E-03 0,04724087 ! membrane to membrane docking GO:0022614 14 6 0,000 9,13E-03 0,04713949 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,13E-03 0,04703855 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 9,13E-03 0,04693804 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,13E-03 0,04683796 ! receptor internalization GO:0031623 10 6 0,000 9,13E-03 0,0467383 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 9,13E-03 0,04663907 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 9,13E-03 0,04654026 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,13E-03 0,04644187 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 9,13E-03 0,04634389 ! protein deubiquitination GO:0016579 14 6 0,000 9,13E-03 0,04624632 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 9,13E-03 0,04614916 ! protein destabilization GO:0031648 9 6 0,000 9,13E-03 0,04605242 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 9,13E-03 0,04595607 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 9,13E-03 0,04586013 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,13E-03 0,04576459 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 9,13E-03 0,04566944 ! progesterone metabolic process GO:0042448 10 6 0,000 9,13E-03 0,04557469 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 9,13E-03 0,04548034 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 9,13E-03 0,04538637 ! negative regulation of axon extension GO:0030517 21 6 0,000 9,13E-03 0,04529279 ! removal of superoxide radicals GO:0019430 11 6 0,000 9,13E-03 0,04519959 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,13E-03 0,04510678 ! determination of adult lifespan GO:0008340 15 6 0,000 9,13E-03 0,04501435 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 9,13E-03 0,0449223 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 9,13E-03 0,04483062 ! cerebellar cortex formation GO:0021697 8 6 0,000 9,13E-03 0,04473931 ! catecholamine transport GO:0051937 9 6 0,000 9,13E-03 0,04464838 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 9,13E-03 0,04455781 ! sensory cilium assembly GO:0035058 10 6 0,000 9,13E-03 0,04446762 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,13E-03 0,04437778 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 9,13E-03 0,04428831 ! maternal placenta development GO:0001893 12 6 0,000 9,13E-03 0,0441992 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 9,13E-03 0,04411045 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,13E-03 0,04402205 ! negative regulation of B cell activation GO:0050869 13 6 0,000 9,13E-03 0,043934 ! protein amino acid prenylation GO:0018346 16 6 0,000 9,13E-03 0,04384631 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,13E-03 0,04375897 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 9,13E-03 0,04367197 ! positive regulation of coagulation GO:0050820 12 6 0,000 9,13E-03 0,04358532 ! positive regulation of immune response GO:0050778 156 96 1,000 9,5E-03 0,04526146 ! protein ubiquitination GO:0016567 217 97 1,000 9,691E-03 0,04607849 ! regulation of protein localization GO:0032880 176 97 1,000 9,691E-03 0,04598761 ! tRNA transcription GO:0009304 14 7 0,000 0,01064383 0,0504115 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01064383 0,05031246 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01064383 0,05021381 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01064383 0,05011555 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01064383 0,05001766 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01064383 0,04992016 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01064383 0,04982304 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01064383 0,0497263 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01064383 0,04962993 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01064383 0,04953393 ! prostate gland development GO:0030850 13 7 0,000 0,01064383 0,04943831 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01064383 0,04934305 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01064383 0,04924816 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01064383 0,04915364 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01064383 0,04905947 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01064383 0,04896567 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01064383 0,04887222 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01064383 0,04877913 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01064383 0,0486864 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01064383 0,04859401 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01064383 0,04850198 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01064383 0,04841029 ! glycolipid transport GO:0046836 10 7 0,000 0,01064383 0,04831895 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01064383 0,04822795 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01064383 0,0481373 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01064383 0,04804699 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01064383 0,04795701 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01064383 0,04786737 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01064383 0,04777807 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01064383 0,0476891 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01064383 0,04760045 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01064383 0,04751214 ! mRNA stabilization GO:0048255 18 7 0,000 0,01064383 0,04742416 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01064383 0,0473365 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01064383 0,04724916 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01064383 0,04716214 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01064383 0,04707545 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01064383 0,04698907 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01064383 0,04690301 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01064383 0,04681727 ! lipoprotein transport GO:0042953 14 7 0,000 0,01064383 0,04673183 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01064383 0,04664671 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01064383 0,0465619 ! rhythmic behavior GO:0007622 15 7 0,000 0,01064383 0,04647739 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01064383 0,0463932 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01064383 0,0463093 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01064383 0,04622571 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01064383 0,04614242 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01064383 0,04605943 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01064383 0,04597674 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01064383 0,04589434 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01064383 0,04581224 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01064383 0,04573044 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01064383 0,04564892 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01064383 0,04556769 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01064383 0,04548676 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01064383 0,04540611 ! spinal cord patterning GO:0021511 13 7 0,000 0,01064383 0,04532574 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01064383 0,04524566 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01064383 0,04516586 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01064383 0,04508635 ! adrenal gland development GO:0030325 17 7 0,000 0,01064383 0,04500711 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01064383 0,04492815 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01064383 0,04484946 ! ovulation GO:0030728 9 7 0,000 0,01064383 0,04477106 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01064383 0,04469292 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01064383 0,04461506 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01064383 0,04453747 ! microtubule nucleation GO:0007020 20 7 0,000 0,01064383 0,04446015 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01064383 0,04438309 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01064383 0,0443063 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01064383 0,04422978 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01064383 0,04415352 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01064383 0,04407753 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01064383 0,04400179 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01064383 0,04392632 ! galactose metabolic process GO:0006012 13 7 0,000 0,01064383 0,0438511 ! vesicle fusion GO:0006906 17 7 0,000 0,01064383 0,04377614 ! response to dietary excess GO:0002021 8 7 0,000 0,01064383 0,04370144 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01064383 0,04362699 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01064383 0,0435528 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01064383 0,04347885 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01064383 0,04340516 ! organ growth GO:0035265 15 7 0,000 0,01064383 0,04333172 ! purine salvage GO:0043101 10 7 0,000 0,01064383 0,04325852 ! nucleoside transport GO:0015858 8 7 0,000 0,01064383 0,04318557 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01064383 0,04311287 ! parturition GO:0007567 14 7 0,000 0,01064383 0,04304041 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01064383 0,04296819 ! rRNA modification GO:0000154 14 7 0,000 0,01064383 0,04289622 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01064383 0,04282449 ! spindle checkpoint GO:0031577 15 7 0,000 0,01064383 0,042753 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01064383 0,04268174 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01064383 0,04261072 ! macrophage differentiation GO:0030225 11 7 0,000 0,01064383 0,04253994 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01064383 0,04246939 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01064383 0,04239908 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01064383 0,042329 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01064383 0,04225915 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01064383 0,04218953 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01064383 0,04212014 ! fibrinolysis GO:0042730 10 7 0,000 0,01064383 0,04205098 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01064383 0,04198204 ! eating behavior GO:0042755 7 7 0,000 0,01064383 0,04191333 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01064383 0,04184484 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01064383 0,04177658 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01064383 0,04170854 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01064383 0,04164072 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01064383 0,04157312 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01064383 0,04150574 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01064383 0,04143858 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01064383 0,04137164 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01064383 0,04130491 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01064383 0,0412384 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01064383 0,0411721 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01064383 0,04110601 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01064383 0,04104013 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01064383 0,04097447 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01064383 0,04090902 ! regulation of meiosis GO:0040020 12 7 0,000 0,01064383 0,04084377 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01064383 0,04077873 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01064383 0,0407139 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01064383 0,04064928 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01064383 0,04058486 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01064383 0,04052064 ! transcription termination GO:0006353 13 7 0,000 0,01064383 0,04045663 ! response to tumor cell GO:0002347 13 7 0,000 0,01064383 0,04039281 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01064383 0,0403292 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01064383 0,04026579 ! anaphase GO:0051322 17 7 0,000 0,01064383 0,04020258 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01064383 0,04013957 ! axonal fasciculation GO:0007413 18 7 0,000 0,01064383 0,04007675 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01064383 0,04001413 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01064383 0,03995171 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01064383 0,03988948 ! diuresis GO:0030146 12 7 0,000 0,01064383 0,03982744 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01064383 0,0397656 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01064383 0,03970394 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01064383 0,03964248 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01064383 0,03958121 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01064383 0,03952013 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01064383 0,03945924 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01064383 0,03939853 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01064383 0,03933801 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01064383 0,03927767 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01064383 0,03921753 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01064383 0,03915756 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01064383 0,03909778 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01064383 0,03903818 ! lymph node development GO:0048535 10 7 0,000 0,01064383 0,03897876 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01064383 0,03891952 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01064383 0,03886046 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01064383 0,03880158 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01064383 0,03874288 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01064383 0,03868436 ! adult feeding behavior GO:0008343 9 7 0,000 0,01064383 0,03862601 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01064383 0,03856784 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01064383 0,03850984 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01064383 0,03845202 ! muscle adaptation GO:0043500 14 7 0,000 0,01064383 0,03839437 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01064383 0,03833689 ! retina homeostasis GO:0001895 12 7 0,000 0,01064383 0,03827959 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01064383 0,03822245 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01064383 0,03816549 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01064383 0,0381087 ! protein prenylation GO:0018342 18 7 0,000 0,01064383 0,03805207 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01064383 0,03799561 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01064383 0,03793932 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01064383 0,0378832 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0121553 0,04319888 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0121553 0,04313517 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,0121553 0,04307164 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0121553 0,0430083 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0121553 0,04294514 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0121553 0,04288217 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0121553 0,04281939 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0121553 0,04275679 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0121553 0,04269437 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0121553 0,04263213 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0121553 0,04257008 ! meiotic prophase I GO:0007128 13 8 0,000 0,0121553 0,0425082 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0121553 0,04244651 ! oligopeptide transport GO:0006857 15 8 0,000 0,0121553 0,04238499 ! UTP metabolic process GO:0046051 8 8 0,000 0,0121553 0,04232365 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0121553 0,04226249 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0121553 0,0422015 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0121553 0,0421407 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0121553 0,04208006 ! succinate metabolic process GO:0006105 14 8 0,000 0,0121553 0,0420196 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0121553 0,04195932 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0121553 0,0418992 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0121553 0,04183926 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0121553 0,04177949 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0121553 0,04171989 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0121553 0,04166046 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0121553 0,0416012 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0121553 0,04154211 ! reflex GO:0060004 16 8 0,000 0,0121553 0,04148318 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0121553 0,04142442 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0121553 0,04136583 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0121553 0,0413074 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0121553 0,04124914 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0121553 0,04119105 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0121553 0,04113311 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0121553 0,04107534 ! pigment granule organization GO:0048753 16 8 0,000 0,0121553 0,04101773 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0121553 0,04096028 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0121553 0,040903 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0121553 0,04084587 ! histidine metabolic process GO:0006547 16 8 0,000 0,0121553 0,0407889 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0121553 0,04073209 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0121553 0,04067544 ! glycine catabolic process GO:0006546 13 8 0,000 0,0121553 0,04061895 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0121553 0,04056261 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0121553 0,04050643 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0121553 0,0404504 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0121553 0,04039453 ! melanin metabolic process GO:0006582 15 8 0,000 0,0121553 0,04033882 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0121553 0,04028325 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0121553 0,04022784 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0121553 0,04017259 ! macrophage activation GO:0042116 12 8 0,000 0,0121553 0,04011748 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0121553 0,04006252 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0121553 0,04000772 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0121553 0,03995306 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0121553 0,03989856 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0121553 0,0398442 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0121553 0,03978999 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0121553 0,03973593 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0121553 0,03968201 ! osteoblast development GO:0002076 16 8 0,000 0,0121553 0,03962824 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0121553 0,03957462 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0121553 0,03952114 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0121553 0,0394678 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0121553 0,03941461 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0121553 0,03936156 ! response to UV-B GO:0010224 16 8 0,000 0,0121553 0,03930866 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0121553 0,0392559 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0121553 0,03920327 ! intermediate filament organization GO:0045109 12 8 0,000 0,0121553 0,03915079 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0121553 0,03909845 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0121553 0,03904625 ! cellular extravasation GO:0045123 12 8 0,000 0,0121553 0,03899419 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0121553 0,03894227 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0121553 0,03889048 ! response to antibiotic GO:0046677 11 8 0,000 0,0121553 0,03883883 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0121553 0,03878732 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0121553 0,03873595 ! DNA topological change GO:0006265 12 8 0,000 0,0121553 0,03868471 ! response to tropane GO:0014073 15 8 0,000 0,0121553 0,03863361 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0121553 0,03858264 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0121553 0,03853181 ! melanosome transport GO:0032402 13 8 0,000 0,0121553 0,03848111 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,0121553 0,03843054 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0121553 0,03838011 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0121553 0,03832981 ! mast cell activation GO:0045576 14 8 0,000 0,0121553 0,03827964 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0121553 0,0382296 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0121553 0,03817969 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0121553 0,03812991 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0121553 0,03808026 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0121553 0,03803074 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0121553 0,03798135 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0121553 0,03793209 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0121553 0,03788296 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0121553 0,03783395 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0121553 0,03778507 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0121553 0,03773631 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0121553 0,03768768 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0121553 0,03763918 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0121553 0,0375908 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0121553 0,03754255 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0121553 0,03749441 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0121553 0,03744641 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0121553 0,03739852 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0121553 0,03735076 ! hormone catabolic process GO:0042447 17 8 0,000 0,0121553 0,03730312 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0121553 0,0372556 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0121553 0,0372082 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0121553 0,03716092 ! ATP catabolic process GO:0006200 11 8 0,000 0,0121553 0,03711376 ! blastocyst growth GO:0001832 19 8 0,000 0,0121553 0,03706672 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0121553 0,0370198 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0121553 0,036973 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0121553 0,03692632 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0121553 0,03687975 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0121553 0,0368333 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0121553 0,03678697 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0121553 0,03674076 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0121553 0,03669466 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0121553 0,03664867 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0121553 0,03660281 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0121553 0,03655705 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0121553 0,03651141 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0121553 0,03646589 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0121553 0,03642048 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0121553 0,03637518 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0121553 0,03632999 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0121553 0,03628492 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01366451 0,04073954 ! axon extension GO:0048675 15 9 0,000 0,01366451 0,04068912 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01366451 0,04063882 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01366451 0,04058865 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01366451 0,0405386 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01366451 0,04048868 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01366451 0,04043888 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01366451 0,0403892 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01366451 0,04033964 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01366451 0,0402902 ! phosphate transport GO:0006817 19 9 0,000 0,01366451 0,04024089 ! reproductive behavior GO:0019098 19 9 0,000 0,01366451 0,04019169 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01366451 0,04014262 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01366451 0,04009367 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01366451 0,04004483 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01366451 0,03999611 ! GTP metabolic process GO:0046039 9 9 0,000 0,01366451 0,03994752 ! RNA methylation GO:0001510 15 9 0,000 0,01366451 0,03989904 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01366451 0,03985067 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01366451 0,03980243 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01366451 0,0397543 ! artery development GO:0060840 24 9 0,000 0,01366451 0,03970629 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01366451 0,03965839 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01366451 0,03961061 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01366451 0,03956294 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01366451 0,03951539 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01366451 0,03946795 ! chemosensory behavior GO:0007635 20 9 0,000 0,01366451 0,03942063 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01366451 0,03937342 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01366451 0,03932632 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01366451 0,03927934 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01366451 0,03923247 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01366451 0,0391857 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01366451 0,03913905 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01366451 0,03909252 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01366451 0,03904609 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01366451 0,03899977 ! protein targeting to ER GO:0045047 22 9 0,000 0,01366451 0,03895356 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01366451 0,03890746 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01366451 0,03886147 ! T cell selection GO:0045058 23 9 0,000 0,01366451 0,03881559 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01366451 0,03876982 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01366451 0,03872415 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01366451 0,0386786 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01366451 0,03863314 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01366451 0,0385878 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01366451 0,03854256 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01366451 0,03849743 ! mannose metabolic process GO:0006013 13 9 0,000 0,01366451 0,0384524 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01366451 0,03840748 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01366451 0,03836267 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01366451 0,03831796 ! receptor clustering GO:0043113 18 9 0,000 0,01366451 0,03827335 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01366451 0,03822884 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01366451 0,03818444 ! ruffle organization GO:0031529 15 9 0,000 0,01366451 0,03814015 ! retinol metabolic process GO:0042572 18 9 0,000 0,01366451 0,03809595 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01366451 0,03805186 ! behavioral fear response GO:0001662 22 9 0,000 0,01366451 0,03800787 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01366451 0,03796398 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01366451 0,03792019 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01366451 0,0378765 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01366451 0,03783292 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01366451 0,03778943 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01366451 0,03774605 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01366451 0,03770276 ! segment specification GO:0007379 13 9 0,000 0,01366451 0,03765957 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01366451 0,03761648 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01366451 0,03757349 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01366451 0,0375306 ! response to amine stimulus GO:0014075 13 9 0,000 0,01366451 0,03748781 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01366451 0,03744511 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01366451 0,03740251 ! erythrocyte development GO:0048821 15 9 0,000 0,01366451 0,03736001 ! gas homeostasis GO:0033483 16 9 0,000 0,01366451 0,0373176 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01366451 0,03727529 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01366451 0,03723308 ! renal water homeostasis GO:0003091 14 9 0,000 0,01366451 0,03719096 ! postreplication repair GO:0006301 22 9 0,000 0,01366451 0,03714893 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01366451 0,037107 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01366451 0,03706517 ! icosanoid secretion GO:0032309 15 9 0,000 0,01366451 0,03702343 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01366451 0,03698178 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01366451 0,03694023 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01366451 0,03689877 ! regulation of cell division GO:0051302 15 9 0,000 0,01366451 0,03685741 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01366451 0,03681613 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01366451 0,03677495 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01366451 0,03673386 ! sterol catabolic process GO:0016127 11 9 0,000 0,01366451 0,03669286 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01366451 0,03665196 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01366451 0,03661114 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01366451 0,03657042 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01366451 0,03652978 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01366451 0,03648924 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01366451 0,03644879 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01366451 0,03640842 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01366451 0,03636815 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01366451 0,03632796 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01366451 0,03628787 ! purine base metabolic process GO:0006144 21 9 0,000 0,01366451 0,03624786 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01366451 0,03620794 ! pigment granule transport GO:0051904 17 9 0,000 0,01366451 0,0361681 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01366451 0,03612836 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01366451 0,0360887 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01366451 0,03604913 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01366451 0,03600965 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01366451 0,03597025 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01517146 0,03989349 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01517146 0,03984994 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01517146 0,03980648 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01517146 0,03976312 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01517146 0,03971985 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01517146 0,03967668 ! synapsis GO:0007129 13 10 0,000 0,01517146 0,0396336 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01517146 0,03959061 ! N-glycan processing GO:0006491 20 10 0,000 0,01517146 0,03954772 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01517146 0,03950492 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01517146 0,03946221 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01517146 0,03941959 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01517146 0,03937707 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01517146 0,03933464 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01517146 0,0392923 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01517146 0,03925005 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01517146 0,03920789 ! androgen metabolic process GO:0008209 17 10 0,000 0,01517146 0,03916582 ! phospholipid efflux GO:0033700 16 10 0,000 0,01517146 0,03912384 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01517146 0,03908195 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01517146 0,03904015 ! lung alveolus development GO:0048286 26 10 0,000 0,01517146 0,03899844 ! pathogenesis GO:0009405 13 10 0,000 0,01517146 0,03895682 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01517146 0,03891529 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01517146 0,03887385 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01517146 0,03883249 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01517146 0,03879122 ! endoderm development GO:0007492 16 10 0,000 0,01517146 0,03875004 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01517146 0,03870895 ! arginine catabolic process GO:0006527 13 10 0,000 0,01517146 0,03866795 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01517146 0,03862703 ! proline metabolic process GO:0006560 13 10 0,000 0,01517146 0,0385862 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01517146 0,03854545 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01517146 0,03850479 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01517146 0,03846422 ! V(D)J recombination GO:0033151 28 10 0,000 0,01517146 0,03842373 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01517146 0,03838333 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01517146 0,03834301 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01517146 0,03830277 ! B cell proliferation GO:0042100 18 10 0,000 0,01517146 0,03826262 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01517146 0,03822256 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01517146 0,03818258 ! multicellular organism growth GO:0035264 18 10 0,000 0,01517146 0,03814268 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01517146 0,03810286 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01517146 0,03806313 ! epithelial cell development GO:0002064 20 10 0,000 0,01517146 0,03802348 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01517146 0,03798392 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01517146 0,03794443 ! macroautophagy GO:0016236 17 10 0,000 0,01517146 0,03790503 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01517146 0,03786571 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01517146 0,03782647 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01517146 0,03778731 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01517146 0,03774823 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01517146 0,03770924 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01517146 0,03767032 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01517146 0,03763149 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01517146 0,03759273 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01517146 0,03755406 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01517146 0,03751546 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01517146 0,03747694 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01517146 0,0374385 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01517146 0,03740015 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01517146 0,03736187 ! response to dsRNA GO:0043331 20 10 0,000 0,01517146 0,03732366 ! DNA ligation GO:0006266 19 10 0,000 0,01517146 0,03728554 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01517146 0,03724749 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01517146 0,03720952 ! melanosome localization GO:0032400 16 10 0,000 0,01517146 0,03717163 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01517146 0,03713382 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01517146 0,03709608 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01517146 0,03705842 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01517146 0,03702083 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01517146 0,03698333 ! mRNA cleavage GO:0006379 17 10 0,000 0,01517146 0,03694589 ! protein sumoylation GO:0016925 15 10 0,000 0,01517146 0,03690854 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01517146 0,03687125 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01517146 0,03683405 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01517146 0,03679692 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01517146 0,03675986 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01517146 0,03672288 ! salivary gland development GO:0007431 27 10 0,000 0,01517146 0,03668597 ! prophase GO:0051324 15 10 0,000 0,01517146 0,03664914 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01517146 0,03661238 ! apical protein localization GO:0045176 15 10 0,000 0,01517146 0,03657569 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01517146 0,03653908 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01517146 0,03650254 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01517146 0,03646608 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01517146 0,03642968 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01517146 0,03639336 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01517146 0,03635711 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01517146 0,03632094 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01517146 0,03628483 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01517146 0,0362488 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01517146 0,03621284 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01517146 0,03617695 ! oocyte development GO:0048599 17 10 0,000 0,01517146 0,03614113 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01517146 0,03610538 ! blastocyst formation GO:0001825 17 10 0,000 0,01517146 0,03606971 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01517146 0,0360341 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01517146 0,03599856 ! activation of innate immune response GO:0002218 12 10 0,000 0,01517146 0,0359631 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01517146 0,0359277 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01517146 0,03589237 ! response to nicotine GO:0035094 20 10 0,000 0,01517146 0,03585711 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01517146 0,03582193 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01517146 0,03578681 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01517146 0,03575176 ! localization within membrane GO:0051668 20 10 0,000 0,01517146 0,03571677 ! respiratory burst GO:0045730 17 11 0,000 0,01667617 0,03922078 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01667617 0,03918248 ! neuron fate specification GO:0048665 17 11 0,000 0,01667617 0,03914425 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01667617 0,0391061 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01667617 0,03906802 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01667617 0,03903002 ! thyroid gland development GO:0030878 26 11 0,000 0,01667617 0,03899209 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01667617 0,03895423 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01667617 0,03891645 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01667617 0,03887874 ! response to pain GO:0048265 24 11 0,000 0,01667617 0,0388411 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01667617 0,03880354 ! T cell proliferation GO:0042098 26 11 0,000 0,01667617 0,03876605 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01667617 0,03872863 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01667617 0,03869128 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01667617 0,03865401 ! bone resorption GO:0045453 16 11 0,000 0,01667617 0,0386168 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01667617 0,03857967 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01667617 0,03854261 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01667617 0,03850562 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01667617 0,0384687 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01667617 0,03843186 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01667617 0,03839508 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01667617 0,03835837 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01667617 0,03832174 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01667617 0,03828517 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01667617 0,03824867 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01667617 0,03821225 ! lipid digestion GO:0044241 18 11 0,000 0,01667617 0,03817589 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01667617 0,0381396 ! UV protection GO:0009650 19 11 0,000 0,01667617 0,03810338 ! adult heart development GO:0007512 14 11 0,000 0,01667617 0,03806723 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01667617 0,03803115 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01667617 0,03799513 ! temperature homeostasis GO:0001659 17 11 0,000 0,01667617 0,03795919 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01667617 0,03792331 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01667617 0,0378875 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01667617 0,03785175 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01667617 0,03781608 ! regulation of organ growth GO:0046620 13 11 0,000 0,01667617 0,03778047 ! pigment granule localization GO:0051875 20 11 0,000 0,01667617 0,03774493 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01667617 0,03770945 ! vasoconstriction GO:0042310 18 11 0,000 0,01667617 0,03767405 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01667617 0,0376387 ! embryonic axis specification GO:0000578 18 11 0,000 0,01667617 0,03760343 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01667617 0,03756822 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01667617 0,03753308 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01667617 0,037498 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01667617 0,03746299 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01667617 0,03742804 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01667617 0,03739316 ! zymogen activation GO:0031638 15 11 0,000 0,01667617 0,03735834 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01667617 0,03732359 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01667617 0,0372889 ! nucleosome positioning GO:0016584 15 11 0,000 0,01667617 0,03725428 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01667617 0,03721972 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01667617 0,03718523 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01667617 0,0371508 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01667617 0,03711643 ! acid secretion GO:0046717 18 11 0,000 0,01667617 0,03708213 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01667617 0,03704788 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01667617 0,03701371 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01667617 0,03697959 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01667617 0,03694554 ! oocyte differentiation GO:0009994 18 11 0,000 0,01667617 0,03691155 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01667617 0,03687763 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01667617 0,03684376 ! cholesterol efflux GO:0033344 19 11 0,000 0,01667617 0,03680996 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01667617 0,03677622 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01667617 0,03674255 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01667617 0,03670893 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01667617 0,03667537 ! embryonic gut development GO:0048566 15 11 0,000 0,01667617 0,03664188 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01667617 0,03660845 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01667617 0,03657508 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01667617 0,03654177 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01667617 0,03650852 ! defense response to fungus GO:0050832 13 11 0,000 0,01667617 0,03647533 ! developmental induction GO:0031128 19 11 0,000 0,01667617 0,0364422 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01667617 0,03640913 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01667617 0,03637612 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01667617 0,03634317 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01667617 0,03631028 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01667617 0,03627745 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01667617 0,03624468 ! nucleus localization GO:0051647 19 11 0,000 0,01667617 0,03621197 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01667617 0,03617931 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01817862 0,03940339 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01817862 0,03936793 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01817862 0,03933252 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01817862 0,03929718 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01817862 0,03926191 ! virus-host interaction GO:0019048 29 12 0,000 0,01817862 0,0392267 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01817862 0,03919155 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01817862 0,03915646 ! cartilage condensation GO:0001502 20 12 0,000 0,01817862 0,03912144 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01817862 0,03908647 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01817862 0,03905158 ! protein complex disassembly GO:0043241 27 12 0,000 0,01817862 0,03901674 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01817862 0,03898197 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01817862 0,03894725 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,01817862 0,0389126 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01817862 0,03887801 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01817862 0,03884349 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01817862 0,03880902 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01817862 0,03877461 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01817862 0,03874027 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01817862 0,03870599 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01817862 0,03867176 ! drug transport GO:0015893 16 12 0,000 0,01817862 0,0386376 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01817862 0,0386035 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01817862 0,03856946 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01817862 0,03853548 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01817862 0,03850155 ! focal adhesion formation GO:0048041 35 12 0,000 0,01817862 0,03846769 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01817862 0,03843389 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01817862 0,03840014 ! forebrain cell migration GO:0021885 21 12 0,000 0,01817862 0,03836646 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01817862 0,03833284 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01817862 0,03829927 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01817862 0,03826576 ! entry into host cell GO:0030260 32 12 0,000 0,01817862 0,03823231 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01817862 0,03819892 ! monoamine transport GO:0015844 18 12 0,000 0,01817862 0,03816559 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01817862 0,03813231 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01817862 0,0380991 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01817862 0,03806594 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01817862 0,03803284 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01817862 0,0379998 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01817862 0,03796681 ! protein homotetramerization GO:0051289 21 12 0,000 0,01817862 0,03793388 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01817862 0,03790101 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01817862 0,03786819 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01817862 0,03783544 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01817862 0,03780274 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01817862 0,03777009 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01817862 0,0377375 ! cranial nerve development GO:0021545 20 12 0,000 0,01817862 0,03770497 ! fucose catabolic process GO:0019317 22 12 0,000 0,01817862 0,03767249 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01817862 0,03764007 ! histone acetylation GO:0016573 26 12 0,000 0,01817862 0,03760771 ! histone methylation GO:0016571 26 12 0,000 0,01817862 0,0375754 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01817862 0,03754315 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01817862 0,03751095 ! gland morphogenesis GO:0022612 29 12 0,000 0,01817862 0,0374788 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01817862 0,03744672 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01817862 0,03741468 ! T cell homeostasis GO:0043029 25 12 0,000 0,01817862 0,03738271 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01817862 0,03735078 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01817862 0,03731891 ! spleen development GO:0048536 22 12 0,000 0,01817862 0,0372871 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01817862 0,03725534 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01817862 0,03722363 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01817862 0,03719198 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01817862 0,03716038 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01817862 0,03712883 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01817862 0,03709734 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01817862 0,0370659 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01817862 0,03703452 ! response to cold GO:0009409 17 12 0,000 0,01817862 0,03700319 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01817862 0,03697191 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01817862 0,03694068 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01967883 0,0399555 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01967883 0,03992181 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01967883 0,03988818 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01967883 0,0398546 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01967883 0,03982108 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01967883 0,03978762 ! lipid localization GO:0010876 28 13 0,000 0,01967883 0,03975421 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01967883 0,03972086 ! organelle fusion GO:0048284 32 13 0,000 0,01967883 0,03968757 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01967883 0,03965433 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01967883 0,03962114 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01967883 0,03958802 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01967883 0,03955494 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01967883 0,03952193 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01967883 0,03948896 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01967883 0,03945606 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01967883 0,0394232 ! methionine metabolic process GO:0006555 27 13 0,000 0,01967883 0,03939041 ! plasma membrane organization GO:0007009 24 13 0,000 0,01967883 0,03935766 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01967883 0,03932497 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01967883 0,03929234 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01967883 0,03925976 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01967883 0,03922723 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01967883 0,03919476 ! response to X-ray GO:0010165 25 13 0,000 0,01967883 0,03916234 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01967883 0,03912997 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01967883 0,03909766 ! exocrine system development GO:0035272 32 13 0,000 0,01967883 0,0390654 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01967883 0,0390332 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01967883 0,03900104 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01967883 0,03896894 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01967883 0,0389369 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01967883 0,0389049 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01967883 0,03887296 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01967883 0,03884107 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01967883 0,03880924 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01967883 0,03877745 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01967883 0,03874572 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01967883 0,03871404 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01967883 0,03868241 ! ribosome assembly GO:0042255 17 13 0,000 0,01967883 0,03865083 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01967883 0,0386193 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01967883 0,03858783 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01967883 0,03855641 ! chromatin silencing GO:0006342 26 13 0,000 0,01967883 0,03852503 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01967883 0,03849371 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01967883 0,03846244 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01967883 0,03843122 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01967883 0,03840005 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01967883 0,03836894 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01967883 0,03833787 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01967883 0,03830685 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01967883 0,03827588 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01967883 0,03824497 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01967883 0,0382141 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01967883 0,03818328 ! embryonic placenta development GO:0001892 23 13 0,000 0,01967883 0,03815251 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01967883 0,03812179 ! insulin secretion GO:0030073 23 13 0,000 0,01967883 0,03809112 ! actin filament polymerization GO:0030041 24 13 0,000 0,01967883 0,0380605 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01967883 0,03802993 ! acrosome reaction GO:0007340 18 13 0,000 0,01967883 0,03799941 ! rRNA transcription GO:0009303 25 14 0,000 0,0211768 0,04085916 ! lactation GO:0007595 26 14 0,000 0,0211768 0,04082642 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,0211768 0,04079373 ! reproductive cellular process GO:0048610 20 14 0,000 0,0211768 0,0407611 ! tRNA modification GO:0006400 20 14 0,000 0,0211768 0,04072852 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0211768 0,04069599 ! regulation of S phase GO:0033261 23 14 0,000 0,0211768 0,04066351 ! water transport GO:0006833 21 14 0,000 0,0211768 0,04063108 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0211768 0,0405987 ! non-recombinational repair GO:0000726 25 14 0,000 0,0211768 0,04056638 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0211768 0,04053411 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0211768 0,04050189 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0211768 0,04046972 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0211768 0,0404376 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0211768 0,04040553 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0211768 0,04037351 ! palate development GO:0060021 31 14 0,000 0,0211768 0,04034155 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0211768 0,04030963 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0211768 0,04027777 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0211768 0,04024595 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0211768 0,04021419 ! arginine metabolic process GO:0006525 17 14 0,000 0,0211768 0,04018247 ! regulation of heart rate GO:0002027 24 14 0,000 0,0211768 0,04015081 ! organic alcohol transport GO:0015850 29 14 0,000 0,0211768 0,04011919 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0211768 0,04008763 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0211768 0,04005611 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0211768 0,04002465 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0211768 0,03999323 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0211768 0,03996186 ! L-amino acid transport GO:0015807 30 14 0,000 0,0211768 0,03993054 ! bone mineralization GO:0030282 17 14 0,000 0,0211768 0,03989927 ! stem cell development GO:0048864 43 14 0,000 0,0211768 0,03986805 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0211768 0,03983688 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0211768 0,03980576 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0211768 0,03977469 ! cerebellum development GO:0021549 21 14 0,000 0,0211768 0,03974366 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0211768 0,03971268 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0211768 0,03968176 ! response to gamma radiation GO:0010332 28 14 0,000 0,0211768 0,03965087 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0211768 0,03962004 ! NADP metabolic process GO:0006739 24 14 0,000 0,0211768 0,03958926 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0211768 0,03955852 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0211768 0,03952783 ! intestinal absorption GO:0050892 25 14 0,000 0,0211768 0,03949719 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0211768 0,03946659 ! oxygen transport GO:0015671 21 14 0,000 0,0211768 0,03943605 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0211768 0,03940555 ! male genitalia development GO:0030539 24 14 0,000 0,0211768 0,0393751 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0211768 0,03934469 ! regulation of axon extension GO:0030516 37 14 0,000 0,0211768 0,03931433 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,0211768 0,03928402 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0211768 0,03925375 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02267252 0,04199391 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02267252 0,04196161 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02267252 0,04192936 ! superoxide anion generation GO:0042554 20 15 0,000 0,02267252 0,04189715 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02267252 0,041865 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02267252 0,04183289 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02267252 0,04180084 ! copper ion transport GO:0006825 20 15 0,000 0,02267252 0,04176883 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02267252 0,04173687 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02267252 0,04170496 ! sulfate transport GO:0008272 23 15 0,000 0,02267252 0,0416731 ! response to cAMP GO:0051591 22 15 0,000 0,02267252 0,04164129 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02267252 0,04160953 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02267252 0,04157781 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02267252 0,04154615 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02267252 0,04151453 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02267252 0,04148296 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02267252 0,04145144 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02267252 0,04141996 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02267252 0,04138854 ! pituitary gland development GO:0021983 29 15 0,000 0,02267252 0,04135716 ! vesicle coating GO:0006901 33 15 0,000 0,02267252 0,04132583 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02267252 0,04129454 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02267252 0,04126331 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02267252 0,04123212 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02267252 0,04120098 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02267252 0,04116988 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02267252 0,04113883 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02267252 0,04110783 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02267252 0,04107688 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02267252 0,04104597 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02267252 0,04101511 ! histone deacetylation GO:0016575 20 15 0,000 0,02267252 0,04098429 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02267252 0,04095352 ! tissue regeneration GO:0042246 26 15 0,000 0,02267252 0,0409228 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02267252 0,04089212 ! water homeostasis GO:0030104 27 15 0,000 0,02267252 0,04086149 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02267252 0,04083091 ! muscle maintenance GO:0046716 26 15 0,000 0,02267252 0,04080037 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02267252 0,04076987 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02267252 0,04073943 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02267252 0,04070902 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02267252 0,04067867 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02267252 0,04064836 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02267252 0,04061809 ! detection of bacterium GO:0016045 18 15 0,000 0,02267252 0,04058787 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02267252 0,04055769 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02267252 0,04052756 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02267252 0,04049747 ! peptide hormone processing GO:0016486 23 15 0,000 0,02267252 0,04046743 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02416601 0,04310114 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02416601 0,04306921 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02416601 0,04303733 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02416601 0,0430055 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02416601 0,04297371 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02416601 0,04294197 ! bone remodeling GO:0046849 27 16 0,000 0,02416601 0,04291028 ! filopodium assembly GO:0046847 32 16 0,000 0,02416601 0,04287864 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02416601 0,04284704 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02416601 0,04281549 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02416601 0,04278398 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02416601 0,04275252 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02416601 0,04272111 ! startle response GO:0001964 28 16 0,000 0,02416601 0,04268974 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02416601 0,04265842 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02416601 0,04262715 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02416601 0,04259592 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02416601 0,04256474 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02416601 0,0425336 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02416601 0,04250251 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02416601 0,04247146 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02416601 0,04244046 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02416601 0,04240951 ! response to osmotic stress GO:0006970 25 16 0,000 0,02416601 0,04237859 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02416601 0,04234773 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02416601 0,04231691 ! fructose metabolic process GO:0006000 25 16 0,000 0,02416601 0,04228613 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02416601 0,0422554 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02416601 0,04222471 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02416601 0,04219407 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02416601 0,04216347 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02416601 0,04213292 ! axon cargo transport GO:0008088 43 16 0,000 0,02416601 0,04210241 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02416601 0,04207195 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02416601 0,04204153 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02416601 0,04201115 ! DNA replication initiation GO:0006270 27 16 0,000 0,02416601 0,04198082 ! neuron recognition GO:0008038 35 16 0,000 0,02416601 0,04195053 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02416601 0,04192028 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02416601 0,04189008 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02416601 0,04185992 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02416601 0,04182981 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02416601 0,04179974 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02416601 0,04176971 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02416601 0,04173972 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02416601 0,04170978 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02416601 0,04167988 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02416601 0,04165002 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02416601 0,04162021 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02416601 0,04159044 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02416601 0,04156071 ! defense response to virus GO:0051607 37 16 0,000 0,02416601 0,04153102 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02565727 0,04406238 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02565727 0,04403096 ! metencephalon development GO:0022037 30 17 0,000 0,02565727 0,04399957 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02565727 0,04396823 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02565727 0,04393694 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02565727 0,04390569 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02565727 0,04387448 ! signal complex assembly GO:0007172 41 17 0,000 0,02565727 0,04384332 ! endothelial cell migration GO:0043542 28 17 0,000 0,02565727 0,04381221 ! inositol metabolic process GO:0006020 28 17 0,000 0,02565727 0,04378113 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02565727 0,04375011 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02565727 0,04371912 ! glial cell development GO:0021782 27 17 0,000 0,02565727 0,04368818 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02565727 0,04365728 ! adult walking behavior GO:0007628 33 17 0,000 0,02565727 0,04362643 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02565727 0,04359562 ! heart looping GO:0001947 30 17 0,000 0,02565727 0,04356485 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02565727 0,04353413 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02565727 0,04350345 ! myoblast differentiation GO:0045445 45 17 0,000 0,02565727 0,04347282 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02565727 0,04344222 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02565727 0,04341167 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02565727 0,04338117 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02565727 0,0433507 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02565727 0,04332028 ! glycine metabolic process GO:0006544 28 17 0,000 0,02565727 0,0432899 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02565727 0,04325956 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02565727 0,04322927 ! NAD metabolic process GO:0019674 29 17 0,000 0,02565727 0,04319902 ! membrane budding GO:0006900 37 17 0,000 0,02565727 0,04316881 ! DNA integration GO:0015074 29 17 0,000 0,02565727 0,04313864 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02565727 0,04310852 ! regulation of protein binding GO:0043393 33 17 0,000 0,02565727 0,04307844 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02565727 0,0430484 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02565727 0,0430184 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02565727 0,04298844 ! genitalia development GO:0048806 30 17 0,000 0,02565727 0,04295852 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02565727 0,04292865 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02565727 0,04289882 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02565727 0,04286903 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02565727 0,04283928 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02565727 0,04280957 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02565727 0,0427799 ! steroid catabolic process GO:0006706 31 17 0,000 0,02565727 0,04275028 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02565727 0,04272069 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02565727 0,04269115 ! gas transport GO:0015669 25 17 0,000 0,02565727 0,04266164 ! organic cation transport GO:0015695 31 17 0,000 0,02565727 0,04263218 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02565727 0,04260276 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02565727 0,04257338 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02565727 0,04254404 ! microspike assembly GO:0030035 36 17 0,000 0,02565727 0,04251474 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02565727 0,04248548 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02565727 0,04245626 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0271463 0,04488935 ! neuron maturation GO:0042551 42 18 0,000 0,0271463 0,04485852 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,0271463 0,04482773 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0271463 0,04479698 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,0271463 0,04476628 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0271463 0,04473562 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0271463 0,044705 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0271463 0,04467442 ! memory GO:0007613 31 18 0,000 0,0271463 0,04464388 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0271463 0,04461339 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0271463 0,04458294 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0271463 0,04455253 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0271463 0,04452216 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,0271463 0,04449183 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0271463 0,04446154 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,0271463 0,04443129 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0271463 0,04440109 ! response to retinoic acid GO:0032526 26 18 0,000 0,0271463 0,04437093 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0271463 0,0443408 ! response to fungus GO:0009620 21 18 0,000 0,0271463 0,04431072 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0271463 0,04428068 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0271463 0,04425068 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0271463 0,04422072 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0271463 0,0441908 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0271463 0,04416092 ! vitamin transport GO:0051180 27 18 0,000 0,0271463 0,04413108 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0271463 0,04410128 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0271463 0,04407153 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,0271463 0,04404181 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0271463 0,04401213 ! nerve development GO:0021675 28 18 0,000 0,0271463 0,04398249 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0271463 0,0439529 ! protein secretion GO:0009306 39 19 0,000 0,0286331 0,04632902 ! positive regulation of translation GO:0045727 30 19 0,000 0,0286331 0,04629788 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0286331 0,04626679 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0286331 0,04623574 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0286331 0,04620473 ! skin development GO:0043588 36 19 0,000 0,0286331 0,04617376 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0286331 0,04614283 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0286331 0,04611195 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0286331 0,0460811 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0286331 0,0460503 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0286331 0,04601954 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0286331 0,04598882 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0286331 0,04595814 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,0286331 0,0459275 ! cerebral cortex development GO:0021987 36 19 0,000 0,0286331 0,0458969 ! pigmentation during development GO:0048066 41 19 0,000 0,0286331 0,04586634 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0286331 0,04583583 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,0286331 0,04580535 ! heme metabolic process GO:0042168 36 19 0,000 0,0286331 0,04577492 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0286331 0,04574452 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0286331 0,04571417 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0286331 0,04568385 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0286331 0,04565358 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0286331 0,04562334 ! peptide cross-linking GO:0018149 37 19 0,000 0,0286331 0,04559315 ! protein export from nucleus GO:0006611 36 19 0,000 0,0286331 0,045563 ! heart process GO:0003015 30 19 0,000 0,0286331 0,04553288 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0286331 0,04550281 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0286331 0,04547277 ! visual learning GO:0008542 36 19 0,000 0,0286331 0,04544278 ! cellular pigmentation GO:0033059 36 19 0,000 0,0286331 0,04541282 ! G1 phase GO:0051318 40 19 0,000 0,0286331 0,0453829 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0286331 0,04535303 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0286331 0,04532319 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,0286331 0,04529339 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0286331 0,04526363 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0286331 0,04523391 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0286331 0,04520423 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0286331 0,04517459 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0286331 0,04514499 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0286331 0,04511542 ! cilium assembly GO:0042384 37 19 0,000 0,0286331 0,0450859 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0286331 0,04505641 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03011768 0,04736153 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03011768 0,0473306 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03011768 0,0472997 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03011768 0,04726885 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03011768 0,04723804 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03011768 0,04720726 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03011768 0,04717653 ! response to vitamin GO:0033273 31 20 0,000 0,03011768 0,04714583 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03011768 0,04711518 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03011768 0,04708457 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03011768 0,04705399 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03011768 0,04702346 ! response to alkaloid GO:0043279 38 20 0,000 0,03011768 0,04699296 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03011768 0,04696251 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03011768 0,04693209 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03011768 0,04690171 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03011768 0,04687138 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03011768 0,04684108 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03011768 0,04681082 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,03011768 0,0467806 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03011768 0,04675042 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03011768 0,04672028 ! body fluid secretion GO:0007589 31 20 0,000 0,03011768 0,04669017 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03011768 0,04666011 ! peptide secretion GO:0002790 35 20 0,000 0,03011768 0,04663008 ! stem cell differentiation GO:0048863 53 20 0,000 0,03011768 0,0466001 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03011768 0,04657015 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,03011768 0,04654024 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03011768 0,04651036 ! sensory perception of pain GO:0019233 30 20 0,000 0,03011768 0,04648053 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03011768 0,04645074 ! diencephalon development GO:0021536 34 20 0,000 0,03011768 0,04642098 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03011768 0,04639126 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03011768 0,04636158 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03011768 0,04633194 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03011768 0,04630233 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03011768 0,04627276 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03011768 0,04624323 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03011768 0,04621374 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03011768 0,04618429 ! regulation of glucose import GO:0046324 29 20 0,000 0,03011768 0,04615487 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03011768 0,04612549 ! actin filament-based movement GO:0030048 43 20 0,000 0,03011768 0,04609615 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03011768 0,04606685 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03011768 0,04603758 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03011768 0,04600835 ! negative regulation of translation GO:0017148 29 20 0,000 0,03011768 0,04597915 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03011768 0,04595 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03011768 0,04592088 ! regulation of cell killing GO:0031341 42 21 0,000 0,03160004 0,04815054 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03160004 0,04812007 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03160004 0,04808963 ! hormone secretion GO:0046879 38 21 0,000 0,03160004 0,04805923 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03160004 0,04802887 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03160004 0,04799855 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03160004 0,04796827 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03160004 0,04793802 ! axis specification GO:0009798 38 21 0,000 0,03160004 0,04790782 ! ovarian follicle development GO:0001541 35 21 0,000 0,03160004 0,04787765 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03160004 0,04784752 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03160004 0,04781742 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03160004 0,04778737 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03160004 0,04775735 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03160004 0,04772737 ! cell aging GO:0007569 44 21 0,000 0,03160004 0,04769743 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03160004 0,04766753 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03160004 0,04763766 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03160004 0,04760783 ! cytolysis GO:0019835 24 21 0,000 0,03160004 0,04757804 ! vasodilation GO:0042311 39 21 0,000 0,03160004 0,04754828 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03160004 0,04751857 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03160004 0,04748889 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03160004 0,04745924 ! oogenesis GO:0048477 36 21 0,000 0,03160004 0,04742964 ! DNA modification GO:0006304 34 21 0,000 0,03160004 0,04740007 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03160004 0,04737053 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03160004 0,04734104 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03160004 0,04731158 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03160004 0,04728216 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03160004 0,04725277 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03160004 0,04722342 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03160004 0,04719411 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03160004 0,04716483 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03160004 0,04713559 ! collagen catabolic process GO:0030574 28 21 0,000 0,03160004 0,04710639 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03160004 0,04707722 ! gut development GO:0048565 39 21 0,000 0,03160004 0,04704809 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03308019 0,04922135 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03308019 0,04919093 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03308019 0,04916055 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03308019 0,0491302 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03308019 0,0490999 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03308019 0,04906962 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03308019 0,04903939 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03308019 0,04900919 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03308019 0,04897903 ! regeneration GO:0031099 41 22 0,000 0,03308019 0,04894891 ! keratinization GO:0031424 28 22 0,000 0,03308019 0,04891883 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03308019 0,04888878 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03308019 0,04885877 ! sensory perception of taste GO:0050909 28 22 0,000 0,03308019 0,04882879 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03308019 0,04879885 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,03308019 0,04876895 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03308019 0,04873909 ! vacuolar transport GO:0007034 36 22 0,000 0,03308019 0,04870926 ! lysosome organization GO:0007040 41 22 0,000 0,03308019 0,04867947 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03308019 0,04864971 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03308019 0,04861999 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03308019 0,04859031 ! fucose metabolic process GO:0006004 39 22 0,000 0,03308019 0,04856067 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03308019 0,04853106 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03308019 0,04850148 ! ureteric bud development GO:0001657 43 22 0,000 0,03308019 0,04847194 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03308019 0,04844244 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03308019 0,04841298 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03308019 0,04838354 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03308019 0,04835415 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03308019 0,04832479 ! sarcomere organization GO:0045214 30 22 0,000 0,03308019 0,04829547 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,03308019 0,04826618 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03308019 0,04823693 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03308019 0,04820771 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03308019 0,04817853 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03308019 0,04814938 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,03308019 0,04812027 ! protein stabilization GO:0050821 39 22 0,000 0,03308019 0,0480912 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03455812 0,05020944 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03455812 0,05017914 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03455812 0,05014887 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03455812 0,05011864 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03455812 0,05008845 ! gluconeogenesis GO:0006094 33 23 0,000 0,03455812 0,0500583 ! viral genome replication GO:0019079 41 23 0,000 0,03455812 0,05002818 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03455812 0,04999809 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03455812 0,04996805 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03455812 0,04993804 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03455812 0,04990806 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03455812 0,04987812 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03455812 0,04984822 ! visual behavior GO:0007632 42 23 0,000 0,03455812 0,04981835 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03455812 0,04978852 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03455812 0,04975873 ! response to ethanol GO:0045471 46 23 0,000 0,03455812 0,04972897 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03455812 0,04969924 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03455812 0,04966955 ! peroxisome organization GO:0007031 37 23 0,000 0,03455812 0,0496399 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03455812 0,04961028 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03455812 0,0495807 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03455812 0,04955115 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03455812 0,04952164 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03455812 0,04949216 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03455812 0,04946272 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03455812 0,04943331 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03455812 0,04940394 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03455812 0,0493746 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03455812 0,0493453 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03455812 0,04931603 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03455812 0,0492868 ! fatty acid transport GO:0015908 44 23 0,000 0,03455812 0,0492576 ! platelet activation GO:0030168 37 23 0,000 0,03455812 0,04922844 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03455812 0,04919931 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03455812 0,04917021 ! hormone transport GO:0009914 40 23 0,000 0,03455812 0,04914115 ! cell-cell recognition GO:0009988 25 23 0,000 0,03455812 0,04911213 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03455812 0,04908314 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03455812 0,04905418 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03455812 0,04902525 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03455812 0,04899636 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03455812 0,04896751 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03603384 0,0510285 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03603384 0,05099848 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03603384 0,0509685 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03603384 0,05093855 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03603384 0,05090864 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03603384 0,05087876 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03603384 0,05084892 ! vesicle docking GO:0048278 47 24 0,000 0,03603384 0,05081912 ! spinal cord development GO:0021510 47 24 0,000 0,03603384 0,05078935 ! vacuole organization GO:0007033 43 24 0,000 0,03603384 0,05075961 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03603384 0,05072991 ! digestive system process GO:0022600 39 24 0,000 0,03603384 0,05070024 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03603384 0,05067061 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03603384 0,05064101 ! regulation of behavior GO:0050795 43 24 0,000 0,03603384 0,05061145 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03603384 0,05058192 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03603384 0,05055243 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03603384 0,05052297 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03603384 0,05049354 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03603384 0,05046415 ! membrane depolarization GO:0051899 39 24 0,000 0,03603384 0,0504348 ! pentose metabolic process GO:0019321 35 24 0,000 0,03603384 0,05040547 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03603384 0,05037618 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03603384 0,05034693 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03603384 0,05031771 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03603384 0,05028852 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03603384 0,05025937 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03603384 0,05023025 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03603384 0,05020117 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03603384 0,05017211 ! regulation of amine transport GO:0051952 40 24 0,000 0,03603384 0,0501431 ! protein tetramerization GO:0051262 52 24 0,000 0,03603384 0,05011411 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03750735 0,05213327 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,03750735 0,05210317 ! myelination GO:0042552 45 25 0,000 0,03750735 0,0520731 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03750735 0,05204307 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03750735 0,05201308 ! phototransduction GO:0007602 33 25 0,000 0,03750735 0,05198312 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03750735 0,05195319 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03750735 0,0519233 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03750735 0,05189344 ! sperm motility GO:0030317 31 25 0,000 0,03750735 0,05186361 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03750735 0,05183382 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03750735 0,05180407 ! receptor metabolic process GO:0043112 46 25 0,000 0,03750735 0,05177435 ! chromosome condensation GO:0030261 45 25 0,000 0,03750735 0,05174466 ! neural crest cell development GO:0014032 54 25 0,000 0,03750735 0,05171501 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03750735 0,05168539 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03750735 0,0516558 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03750735 0,05162625 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03750735 0,05159673 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03750735 0,05156725 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03750735 0,0515378 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03750735 0,05150838 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,03750735 0,051479 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03750735 0,05144965 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03750735 0,05142033 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03750735 0,05139105 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03750735 0,0513618 ! telomere organization GO:0032200 43 25 0,000 0,03750735 0,05133259 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03750735 0,0513034 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03750735 0,05127425 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03897866 0,05325534 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03897866 0,05322512 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03897866 0,05319493 ! initiation of viral infection GO:0019059 57 26 0,000 0,03897866 0,05316477 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03897866 0,05313465 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03897866 0,05310456 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03897866 0,05307451 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03897866 0,05304449 ! molting cycle process GO:0022404 50 26 0,000 0,03897866 0,05301451 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03897866 0,05298455 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03897866 0,05295464 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,03897866 0,05292475 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03897866 0,0528949 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03897866 0,05286508 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03897866 0,0528353 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03897866 0,05280555 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,03897866 0,05277584 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03897866 0,05274615 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03897866 0,0527165 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03897866 0,05268689 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03897866 0,0526573 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03897866 0,05262776 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03897866 0,05259824 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03897866 0,05256876 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03897866 0,05253931 ! blastocyst development GO:0001824 49 26 0,000 0,03897866 0,05250989 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03897866 0,0524805 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03897866 0,05245115 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03897866 0,05242183 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,04044777 0,05436723 ! neuron fate commitment GO:0048663 48 27 0,000 0,04044777 0,05433687 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04044777 0,05430655 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04044777 0,05427626 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,04044777 0,05424601 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04044777 0,05421579 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04044777 0,0541856 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04044777 0,05415545 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04044777 0,05412533 ! fat cell differentiation GO:0045444 50 27 0,000 0,04044777 0,05409524 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04044777 0,05406519 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04044777 0,05403517 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04044777 0,05400518 ! autophagy GO:0006914 41 27 0,000 0,04044777 0,05397523 ! male gonad development GO:0008584 44 27 0,000 0,04044777 0,05394531 ! response to toxin GO:0009636 47 27 0,000 0,04044777 0,05391542 ! primary neural tube formation GO:0014020 51 27 0,000 0,04044777 0,05388557 ! base-excision repair GO:0006284 41 27 0,000 0,04044777 0,05385575 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04044777 0,05382596 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04044777 0,05379621 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04044777 0,05376648 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04044777 0,0537368 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04044777 0,05370714 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04044777 0,05367752 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04044777 0,05364793 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04044777 0,05361837 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04191468 0,05553234 ! circadian rhythm GO:0007623 50 28 0,000 0,04191468 0,05550178 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04191468 0,05547125 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04191468 0,05544075 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04191468 0,05541029 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04191468 0,05537986 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04191468 0,05534947 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04191468 0,05531911 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04191468 0,05528878 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04191468 0,05525848 ! synaptogenesis GO:0007416 42 28 0,000 0,04191468 0,05522822 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,04191468 0,05519799 ! lipid oxidation GO:0034440 43 28 0,000 0,04191468 0,0551678 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04191468 0,05513763 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04191468 0,0551075 ! translational initiation GO:0006413 65 29 0,000 0,0433794 0,0570021 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0433794 0,05697098 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0433794 0,0569399 ! regulation of pH GO:0006885 43 29 0,000 0,0433794 0,05690886 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0433794 0,05687784 ! catechol metabolic process GO:0009712 54 29 0,000 0,0433794 0,05684686 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0433794 0,05681592 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0433794 0,05678501 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0433794 0,05675413 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0433794 0,05672328 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0433794 0,05669247 ! cell fate determination GO:0001709 60 29 0,000 0,0433794 0,0566617 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0433794 0,05663095 ! detection of light stimulus GO:0009583 38 29 0,000 0,0433794 0,05660024 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,0433794 0,05656956 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,0433794 0,05653892 ! tissue homeostasis GO:0001894 48 29 0,000 0,0433794 0,05650831 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,0433794 0,05647773 ! phenol metabolic process GO:0018958 55 30 0,000 0,04484193 0,05835029 ! zinc ion transport GO:0006829 45 30 0,000 0,04484193 0,05831875 ! membrane docking GO:0022406 61 30 0,000 0,04484193 0,05828724 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04484193 0,05825577 ! cell junction assembly GO:0034329 78 30 0,000 0,04484193 0,05822433 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04484193 0,05819293 ! acute-phase response GO:0006953 49 30 0,000 0,04484193 0,05816156 ! myofibril assembly GO:0030239 47 30 0,000 0,04484193 0,05813022 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,04484193 0,05809892 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04484193 0,05806765 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04484193 0,05803641 ! phospholipid transport GO:0015914 51 30 0,000 0,04484193 0,05800521 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04484193 0,05797404 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04484193 0,0579429 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04484193 0,0579118 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04484193 0,05788073 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04484193 0,0578497 ! eye morphogenesis GO:0048592 60 30 0,000 0,04484193 0,0578187 ! regulation of B cell activation GO:0050864 50 30 0,000 0,04484193 0,05778773 ! response to heat GO:0009408 50 30 0,000 0,04484193 0,05775679 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04630227 0,05960581 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04630227 0,05957394 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04630227 0,0595421 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04630227 0,05951029 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04630227 0,05947852 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04630227 0,05944678 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,04630227 0,05941508 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04630227 0,0593834 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04630227 0,05935177 ! ovulation cycle process GO:0022602 49 31 0,000 0,04630227 0,05932016 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04630227 0,05928859 ! peptide transport GO:0015833 55 31 0,000 0,04630227 0,05925706 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04630227 0,05922555 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04630227 0,05919408 ! natural killer cell activation GO:0030101 45 31 0,000 0,04630227 0,05916265 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04630227 0,05913125 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04630227 0,05909988 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04630227 0,05906854 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04630227 0,05903724 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04630227 0,05900597 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04776043 0,06083197 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04776043 0,06079978 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04776043 0,06076763 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04776043 0,06073551 ! cholesterol transport GO:0030301 56 32 0,000 0,04776043 0,06070343 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04776043 0,06067138 ! spliceosome assembly GO:0000245 67 32 0,000 0,04776043 0,06063936 ! spindle organization GO:0007051 46 32 0,000 0,04776043 0,06060738 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04776043 0,06057543 ! metanephros development GO:0001656 74 32 0,000 0,04776043 0,06054351 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04776043 0,06051163 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04776043 0,06047978 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04776043 0,06044797 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04776043 0,06041619 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,04776043 0,06038444 ! muscle cell development GO:0055001 49 32 0,000 0,04776043 0,06035273 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04776043 0,06032104 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04776043 0,0602894 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,04776043 0,06025778 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,04776043 0,0602262 ! ovulation cycle GO:0042698 51 32 0,000 0,04776043 0,06019465 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04776043 0,06016314 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04776043 0,06013165 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04776043 0,0601002 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04776043 0,06006879 ! gene silencing GO:0016458 65 32 0,000 0,04776043 0,0600374 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0492164 0,06183534 ! post-embryonic development GO:0009791 69 33 0,000 0,0492164 0,06180306 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0492164 0,06177082 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0492164 0,06173862 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0492164 0,06170644 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0492164 0,06167431 ! sterol transport GO:0015918 57 33 0,000 0,0492164 0,0616422 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0492164 0,06161013 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0492164 0,06157809 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0492164 0,06154608 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0492164 0,06151411 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0492164 0,06148217 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,0506702 0,06326544 ! glial cell differentiation GO:0010001 63 34 0,000 0,0506702 0,06323263 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,0506702 0,06319985 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,0506702 0,0631671 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,0506702 0,06313439 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,0506702 0,06310171 ! mismatch repair GO:0006298 46 34 0,000 0,0506702 0,06306907 ! spermatid development GO:0007286 63 34 0,000 0,0506702 0,06303645 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,0506702 0,06300388 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,0506702 0,06297133 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,05212182 0,06474192 ! negative regulation of secretion GO:0051048 63 35 0,000 0,05212182 0,06470852 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,05212182 0,06467515 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,05212182 0,06464181 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,05212182 0,06460851 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,05212182 0,06457524 ! female gonad development GO:0008585 58 35 0,000 0,05212182 0,064542 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,05212182 0,0645088 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,05212182 0,06447563 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,05212182 0,0644425 ! cytokine production GO:0001816 59 35 0,000 0,05212182 0,0644094 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,05212182 0,06437634 ! neural tube formation GO:0001841 67 35 0,000 0,05212182 0,06434331 ! vesicle localization GO:0051648 64 35 0,000 0,05212182 0,06431031 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,05357128 0,06606483 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,05357128 0,06603099 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,05357128 0,06599718 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,05357128 0,0659634 ! cell junction organization GO:0034330 86 36 0,000 0,05357128 0,06592966 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,05357128 0,06589596 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,05357128 0,06586228 ! positive regulation of cell development GO:0010720 80 36 0,000 0,05357128 0,06582865 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,05357128 0,06579504 ! regulation of proteolysis GO:0030162 72 36 0,000 0,05357128 0,06576147 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,05357128 0,06572794 ! aerobic respiration GO:0009060 55 36 0,000 0,05357128 0,06569444 ! embryonic organ development GO:0048568 57 36 0,000 0,05357128 0,06566097 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,05357128 0,06562754 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,05357128 0,06559414 ! RNA export from nucleus GO:0006405 56 37 0,000 0,05501856 0,06733197 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05501856 0,06729774 ! meiosis I GO:0007127 65 37 0,000 0,05501856 0,06726354 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,05501856 0,06722938 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05501856 0,06719525 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05501856 0,06716116 ! organic anion transport GO:0015711 68 37 0,000 0,05501856 0,06712711 ! tissue remodeling GO:0048771 76 37 0,000 0,05501856 0,06709308 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05501856 0,06705909 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05501856 0,06702514 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05501856 0,06699122 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,05501856 0,06695734 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05501856 0,06692348 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05501856 0,06688967 ! pigment metabolic process GO:0042440 80 37 0,000 0,05501856 0,06685588 ! spermatid differentiation GO:0048515 66 37 0,000 0,05501856 0,06682214 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,05501856 0,06678842 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,05646368 0,06850812 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,05646368 0,06847359 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,05646368 0,0684391 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,05646368 0,06840464 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,05646368 0,06837021 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,05646368 0,06833582 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,05646368 0,06830146 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,05646368 0,06826714 ! lipid homeostasis GO:0055088 67 38 0,000 0,05646368 0,06823285 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,05646368 0,0681986 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,05646368 0,06816438 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,05646368 0,06813019 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,05646368 0,06809604 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,05646368 0,06806193 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,05646368 0,06802784 ! mRNA catabolic process GO:0006402 71 39 0,000 0,05790663 0,06973141 ! learning GO:0007612 77 39 0,000 0,05790663 0,06969653 ! ear morphogenesis GO:0042471 60 39 0,000 0,05790663 0,06966168 ! organic ether metabolic process GO:0018904 55 39 0,000 0,05790663 0,06962687 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05790663 0,06959209 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05790663 0,06955734 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05790663 0,06952263 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05790663 0,06948796 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05790663 0,06945332 ! RNA modification GO:0009451 57 39 0,000 0,05790663 0,06941871 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05790663 0,06938414 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,05934743 0,07107512 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05934743 0,07103976 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05934743 0,07100443 ! feeding behavior GO:0007631 59 40 0,000 0,05934743 0,07096914 ! negative regulation of binding GO:0051100 72 40 0,000 0,05934743 0,07093389 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,05934743 0,07089867 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05934743 0,07086348 ! maintenance of protein location GO:0045185 91 40 0,000 0,05934743 0,07082833 ! cytokinesis GO:0000910 72 40 0,000 0,05934743 0,07079322 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06078607 0,07247338 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06078607 0,07243749 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06078607 0,07240163 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06078607 0,0723658 ! gliogenesis GO:0042063 88 41 0,000 0,06078607 0,07233001 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06078607 0,07229426 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06078607 0,07225854 ! T cell differentiation GO:0030217 81 41 0,000 0,06078607 0,07222286 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,06078607 0,07218721 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06078607 0,0721516 ! female gamete generation GO:0007292 61 41 0,000 0,06078607 0,07211602 ! polyol metabolic process GO:0019751 66 41 0,000 0,06078607 0,07208048 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06078607 0,07204497 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06222256 0,07371122 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06222256 0,07367494 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,06222256 0,0736387 ! regulation of tube size GO:0035150 71 42 0,000 0,06222256 0,0736025 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06222256 0,07356633 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,06222256 0,0735302 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,06222256 0,0734941 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,06222256 0,07345804 ! neuron migration GO:0001764 79 42 0,000 0,06222256 0,07342201 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06222256 0,07338602 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,06222256 0,07335006 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0636569 0,07500416 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0636569 0,07496745 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0636569 0,07493077 ! glucose transport GO:0015758 65 43 0,000 0,0636569 0,07489413 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,0636569 0,07485753 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0636569 0,07482096 ! neural tube development GO:0021915 77 43 0,000 0,0636569 0,07478442 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,0636569 0,07474793 ! striated muscle contraction GO:0006941 77 43 0,000 0,0636569 0,07471146 ! phagocytosis GO:0006909 90 43 0,000 0,0636569 0,07467504 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0636569 0,07463865 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,06508909 0,07628074 ! hexose transport GO:0008645 67 44 0,000 0,06508909 0,0762436 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,06508909 0,0762065 ! double-strand break repair GO:0006302 81 44 0,000 0,06508909 0,07616943 ! biopolymer methylation GO:0043414 84 44 0,000 0,06508909 0,0761324 ! B cell differentiation GO:0030183 107 44 0,000 0,06508909 0,07609541 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,06508909 0,07605845 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,06508909 0,07602153 ! developmental growth GO:0048589 82 44 0,000 0,06508909 0,07598465 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,06651914 0,07761642 ! glycolysis GO:0006096 65 45 0,000 0,06651914 0,0775788 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,06651914 0,07754121 ! leukocyte migration GO:0050900 68 45 0,000 0,06651914 0,07750366 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,06651914 0,07746615 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,06651914 0,07742867 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,06651914 0,07739123 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,06651914 0,07735382 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,06651914 0,07731645 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,06651914 0,07727912 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,06651914 0,07724182 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,06651914 0,07720456 ! cell growth GO:0016049 84 45 0,000 0,06651914 0,07716734 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,06794705 0,07878584 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,06794705 0,07874789 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,06794705 0,07870997 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,06794705 0,07867209 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,06794705 0,07863425 ! pigmentation GO:0043473 100 46 0,000 0,06794705 0,07859645 ! response to insulin stimulus GO:0032868 95 46 0,000 0,06794705 0,07855868 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06937283 0,0801686 ! response to calcium ion GO:0051592 81 47 0,000 0,06937283 0,08013011 ! endosome transport GO:0016197 108 47 0,000 0,06937283 0,08009166 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,06937283 0,08005325 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06937283 0,08001487 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06937283 0,07997653 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06937283 0,07993823 ! JNK cascade GO:0007254 91 47 0,000 0,06937283 0,07989996 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,06937283 0,07986173 ! methylation GO:0032259 90 47 0,000 0,06937283 0,07982354 ! protein homooligomerization GO:0051260 76 47 0,000 0,06937283 0,07978538 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,07079647 0,0813838 ! mitochondrial transport GO:0006839 82 48 0,000 0,07079647 0,08134494 ! Notch signaling pathway GO:0007219 96 48 0,000 0,07079647 0,08130611 ! cellular component disassembly GO:0022411 86 48 0,000 0,07079647 0,08126732 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,07079647 0,08122856 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,07079647 0,08118985 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,07079647 0,08115117 ! activation of caspase activity GO:0006919 84 48 0,000 0,07079647 0,08111252 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,07079647 0,08107392 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,07079647 0,08103535 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,07079647 0,08099681 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,07079647 0,08095832 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07221798 0,08254463 ! regulation of action potential GO:0001508 95 49 0,000 0,07221798 0,08250544 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,07221798 0,08246628 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07221798 0,08242716 ! regulation of ion transport GO:0043269 77 49 0,000 0,07221798 0,08238807 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,07221798 0,08234903 ! peptide metabolic process GO:0006518 76 49 0,000 0,07221798 0,08231002 ! response to temperature stimulus GO:0009266 76 49 0,000 0,07221798 0,08227105 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07221798 0,08223211 ! endocrine system development GO:0035270 104 49 0,000 0,07221798 0,08219321 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,07221798 0,08215435 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07221798 0,08211552 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07221798 0,08207674 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07363736 0,08365037 ! neuromuscular process GO:0050905 99 50 0,000 0,07363736 0,08361089 ! inner ear development GO:0048839 79 50 0,000 0,07363736 0,08357145 ! histone modification GO:0016570 91 50 0,000 0,07363736 0,08353205 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,07363736 0,08349269 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,07363736 0,08345336 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,07363736 0,08341407 ! positive regulation of binding GO:0051099 78 51 0,000 0,07505462 0,08497948 ! viral infectious cycle GO:0019058 99 51 0,000 0,07505462 0,08493951 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,07505462 0,08489958 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,07505462 0,08485968 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,07505462 0,08481982 ! excretion GO:0007588 83 51 0,000 0,07505462 0,08478 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,07505462 0,08474022 ! chromatin remodeling GO:0006338 109 51 0,000 0,07505462 0,08470047 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,07505462 0,08466076 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,07505462 0,08462109 ! vesicle organization GO:0016050 107 51 0,000 0,07505462 0,08458145 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,07505462 0,08454186 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,07505462 0,08450229 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,07505462 0,08446277 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,07646975 0,08601506 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,07646975 0,08597487 ! membrane fusion GO:0006944 110 52 0,000 0,07646975 0,08593471 ! positive regulation of growth GO:0045927 90 52 0,000 0,07646975 0,08589459 ! covalent chromatin modification GO:0016569 101 52 0,000 0,07646975 0,08585451 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,07646975 0,08581447 ! amino acid activation GO:0043038 92 52 0,000 0,07646975 0,08577446 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,07646975 0,08573449 ! synapse organization GO:0050808 85 52 0,000 0,07646975 0,08569456 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,07788277 0,0872374 ! RNA catabolic process GO:0006401 93 53 0,000 0,07788277 0,08719681 ! regulation of translational initiation GO:0006446 82 53 0,000 0,07788277 0,08715625 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,07788277 0,08711573 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,07788277 0,08707525 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,07788277 0,08703481 ! cell maturation GO:0048469 100 53 0,000 0,07788277 0,0869944 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,07788277 0,08695403 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,07788277 0,0869137 ! response to UV GO:0009411 104 53 0,000 0,07788277 0,08687341 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,07929367 0,0884062 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,07929367 0,08836525 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,07929367 0,08832434 ! cell recognition GO:0008037 85 54 0,000 0,07929367 0,08828347 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,07929367 0,08824263 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,07929367 0,08820184 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,07929367 0,08816108 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,08070246 0,08968597 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,08070246 0,08964457 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08070246 0,0896032 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,08070246 0,08956187 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08070246 0,08952058 ! aging GO:0007568 103 55 0,000 0,08070246 0,08947932 ! heart morphogenesis GO:0003007 97 55 0,000 0,08070246 0,08943811 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,08070246 0,08939693 ! RNA elongation GO:0006354 79 55 0,000 0,08070246 0,08935579 ! nuclear export GO:0051168 97 55 0,000 0,08070246 0,08931469 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,08070246 0,08927362 ! regulation of actin filament length GO:0030832 105 56 0,000 0,08210915 0,09078796 ! sensory perception of smell GO:0007608 80 56 0,000 0,08210915 0,09074626 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,08210915 0,09070459 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,08210915 0,09066297 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,08210915 0,09062138 ! regulation of DNA replication GO:0006275 101 56 0,000 0,08210915 0,09057983 ! proton transport GO:0015992 94 56 0,000 0,08210915 0,09053832 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,08210915 0,09049684 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,08351372 0,09200276 ! muscle fiber development GO:0048747 112 57 0,000 0,08351372 0,09196065 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,08351372 0,09191858 ! lipid modification GO:0030258 97 57 0,000 0,08351372 0,09187655 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,08351372 0,09183456 ! hydrogen transport GO:0006818 97 58 0,000 0,0849162 0,09333411 ! regulation of endocytosis GO:0030100 91 58 0,000 0,0849162 0,09329149 ! adult behavior GO:0030534 99 58 0,000 0,0849162 0,09324891 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,0849162 0,09320637 ! positive regulation of secretion GO:0051047 95 59 0,000 0,08631657 0,09470026 ! regulation of cellular component size GO:0032535 109 59 0,000 0,08631657 0,0946571 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,08631657 0,09461397 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,08631657 0,09457089 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,08631657 0,09452784 ! DNA catabolic process GO:0006308 86 59 0,000 0,08631657 0,09448484 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,08631657 0,09444187 ! establishment of organelle localization GO:0051656 109 59 0,000 0,08631657 0,09439894 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,08771485 0,09588457 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,08771485 0,09584102 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,08771485 0,09579752 ! regulation of heart contraction GO:0008016 110 60 0,000 0,08771485 0,09575405 ! camera-type eye development GO:0043010 116 60 0,000 0,08771485 0,09571062 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,08771485 0,09566724 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,08771485 0,09562389 ! kidney development GO:0001822 122 60 0,000 0,08771485 0,09558058 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,08911103 0,09705801 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,08911103 0,09701409 ! tRNA processing GO:0008033 89 61 0,000 0,08911103 0,09697022 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,08911103 0,09692638 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,08911103 0,09688258 ! ear development GO:0043583 103 62 0,000 0,09050513 0,09835381 ! viral reproductive process GO:0022415 126 62 0,000 0,09050513 0,09830941 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09050513 0,09826504 ! gonad development GO:0008406 98 62 0,000 0,09050513 0,09822072 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,09050513 0,09817644 ! regulation of mitosis GO:0007088 105 63 0,000 0,09189713 0,09964151 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,09189713 0,09959662 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,09189713 0,09955178 ! detection of external stimulus GO:0009581 91 63 0,000 0,09189713 0,09950698 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,09189713 0,09946222 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,09328706 0,10092116 ! cell redox homeostasis GO:0045454 102 64 0,000 0,09328706 0,1008758 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,09328706 0,10083049 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,09328706 0,10078521 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,09328706 0,10073997 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0946749 0,10219282 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0946749 0,102147 ! germ cell development GO:0007281 118 65 0,000 0,0946749 0,10210121 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,0946749 0,10205547 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,09606066 0,10350289 ! actin filament organization GO:0007015 148 66 0,000 0,09606066 0,10345656 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,09606066 0,10341027 ! extracellular matrix organization GO:0030198 133 66 0,000 0,09606066 0,10336402 ! secondary metabolic process GO:0019748 116 66 0,000 0,09606066 0,10331782 ! developmental maturation GO:0021700 116 66 0,000 0,09606066 0,10327165 ! cell projection assembly GO:0030031 120 66 0,000 0,09606066 0,10322553 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,09744435 0,10466567 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,09744435 0,10461897 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,09744435 0,1045723 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,09744435 0,10452568 ! activation of MAPK activity GO:0000187 115 67 0,000 0,09744435 0,1044791 ! lung development GO:0030324 144 67 0,000 0,09744435 0,10443256 ! chromosome segregation GO:0007059 113 67 0,000 0,09744435 0,10438607 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,09744435 0,10433961 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,09744435 0,1042932 ! hexose catabolic process GO:0019320 104 67 0,000 0,09744435 0,10424682 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,09744435 0,10420049 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,09744435 0,1041542 ! amino acid transport GO:0006865 125 68 0,000 0,09882597 0,10558405 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,09882597 0,10553718 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,09882597 0,10549036 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,09882597 0,10544358 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,09882597 0,10539684 ! regulation of lipase activity GO:0060191 130 68 0,000 0,09882597 0,10535014 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,09882597 0,10530349 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,10020551 0,10672619 ! negative regulation of cell size GO:0045792 134 69 0,000 0,10020551 0,10667897 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,10020551 0,10663178 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,10020551 0,10658464 ! urogenital system development GO:0001655 137 69 0,000 0,10020551 0,10653754 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,10020551 0,10649049 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,10020551 0,10644347 ! antigen processing and presentation GO:0019882 104 69 0,000 0,10020551 0,1063965 ! respiratory tube development GO:0030323 150 70 0,000 0,10158299 0,10781151 ! amine catabolic process GO:0009310 117 71 0,000 0,10295841 0,10922308 ! reproductive structure development GO:0048608 113 71 0,000 0,10295841 0,10917494 ! B cell activation GO:0042113 160 71 0,000 0,10295841 0,10912685 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,10295841 0,10907879 ! regulation of immune effector process GO:0002697 137 71 0,000 0,10295841 0,10903078 ! regulation of caspase activity GO:0043281 122 72 0,000 0,10433177 0,11043653 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,10433177 0,11038797 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,10433177 0,11033945 ! carbohydrate transport GO:0008643 110 72 0,000 0,10433177 0,11029097 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,10433177 0,11024253 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,10433177 0,11019413 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,10433177 0,11014578 ! respiratory system development GO:0060541 153 72 0,000 0,10433177 0,11009747 ! learning or memory GO:0007611 147 73 0,000 0,10570307 0,11149565 ! regulation of blood pressure GO:0008217 125 73 0,000 0,10570307 0,1114468 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,10570307 0,11139798 ! axon guidance GO:0007411 139 73 0,000 0,10570307 0,11134921 ! fertilization GO:0009566 90 73 0,000 0,10570307 0,11130048 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,10707232 0,11269291 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 0,000 0,10707232 0,11264364 ! meiosis GO:0007126 121 74 0,000 0,10707232 0,1125944 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,10707232 0,11254521 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,10707232 0,11249607 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,10707232 0,11244696 ! eye development GO:0001654 143 74 0,000 0,10707232 0,1123979 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,10843951 0,11378346 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,10843951 0,11373386 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,10843951 0,1136843 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,10843951 0,11363479 ! meiotic cell cycle GO:0051321 122 75 0,000 0,10843951 0,11358532 ! rhythmic process GO:0048511 128 75 0,000 0,10843951 0,11353589 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,10843951 0,1134865 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,10980466 0,11486522 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,10980466 0,1148153 ! defense response to bacterium GO:0042742 89 76 0,000 0,10980466 0,11476543 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,10980466 0,1147156 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,10980466 0,11466581 ! regulation of catabolic process GO:0009894 161 76 0,000 0,10980466 0,11461606 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,11116777 0,11598857 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,11116777 0,11593829 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,11116777 0,11588806 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,11116777 0,11583787 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,11252883 0,11720535 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,11252883 0,11715463 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,11252883 0,11710396 ! protein oligomerization GO:0051259 139 78 0,000 0,11252883 0,11705333 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,11388785 0,1184158 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,11388785 0,11836465 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,11388785 0,11831354 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,11388785 0,11826248 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,11388785 0,11821146 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,11388785 0,11816049 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,11524484 0,11951684 ! response to metal ion GO:0010038 140 80 0,000 0,11524484 0,11946535 ! muscle cell differentiation GO:0042692 159 80 0,000 0,11524484 0,1194139 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,11524484 0,11936249 ! protein import into nucleus GO:0006606 158 80 0,000 0,11524484 0,11931113 ! T cell activation GO:0042110 168 81 0,000 0,11659979 0,12066198 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,11659979 0,1206101 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,11659979 0,12055827 ! digestion GO:0007586 112 81 0,000 0,11659979 0,12050648 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,11659979 0,12045474 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,11659979 0,12040304 ! nuclear import GO:0051170 161 81 0,000 0,11659979 0,12035139 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,11659979 0,12029978 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,11795271 0,12164347 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,11795271 0,12159136 ! response to drug GO:0042493 143 82 0,000 0,11795271 0,12153928 ! response to nutrient GO:0007584 125 82 0,000 0,11795271 0,12148725 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,11795271 0,12143527 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,11795271 0,12138333 ! response to oxygen levels GO:0070482 176 83 0,000 0,11930361 0,12272103 ! regulation of lyase activity GO:0051339 160 83 0,000 0,11930361 0,12266858 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,12065248 0,12400251 ! negative regulation of transport GO:0051051 153 84 0,000 0,12065248 0,12394956 ! negative regulation of growth GO:0045926 155 84 0,000 0,12065248 0,12389666 ! regulation of ligase activity GO:0051340 142 84 0,000 0,12065248 0,1238438 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,12065248 0,12379099 ! response to unfolded protein GO:0006986 131 85 0,000 0,12199933 0,12511952 ! nucleosome assembly GO:0006334 122 85 0,000 0,12199933 0,12506621 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,12199933 0,12501294 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,12199933 0,12495973 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,12334417 0,12628343 ! response to inorganic substance GO:0010035 153 86 0,000 0,12334417 0,12622972 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,12334417 0,12617605 ! chromatin assembly GO:0031497 124 86 0,000 0,12334417 0,12612242 ! tube morphogenesis GO:0035239 176 86 0,000 0,12334417 0,12606885 ! mitochondrion organization GO:0007005 148 86 0,000 0,12334417 0,12601531 ! alcohol catabolic process GO:0046164 130 86 0,000 0,12334417 0,12596183 ! amine transport GO:0015837 155 86 0,000 0,12334417 0,12590838 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,12468698 0,12722514 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,12468698 0,12717121 ! protein localization in nucleus GO:0034504 176 87 0,000 0,12468698 0,12711732 ! cellular respiration GO:0045333 135 88 0,000 0,12602779 0,12842984 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,12602779 0,12837547 ! regulation of DNA binding GO:0051101 155 88 0,000 0,12602779 0,12832114 ! regulation of neurological system process GO:0031644 148 88 0,000 0,12602779 0,12826686 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,12602779 0,12821263 ! cellular defense response GO:0006968 114 89 0,000 0,12736659 0,12951987 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,12736659 0,12946515 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,12736659 0,12941048 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,12870338 0,13071352 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,12870338 0,13065836 ! sex differentiation GO:0007548 145 90 0,000 0,12870338 0,13060326 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,12870338 0,1305482 ! sterol metabolic process GO:0016125 152 91 0,000 0,13003816 0,13184653 ! response to protein stimulus GO:0051789 149 91 0,000 0,13003816 0,13179099 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,13003816 0,1317355 ! regulation of defense response GO:0031347 149 92 0,000 0,13137095 0,13302967 ! nucleosome organization GO:0034728 138 92 0,000 0,13137095 0,13297371 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,13137095 0,13291779 ! vitamin metabolic process GO:0006766 139 92 0,000 0,13137095 0,13286192 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,13270174 0,13415142 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,13270174 0,13409508 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,13270174 0,13403878 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,13270174 0,13398254 ! regulation of membrane potential GO:0042391 164 93 0,000 0,13270174 0,13392634 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,13270174 0,13387018 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,13403053 0,13515401 ! female pregnancy GO:0007565 164 94 0,000 0,13403053 0,13509739 ! transcription initiation GO:0006352 153 94 0,000 0,13403053 0,13504081 ! regulation of T cell activation GO:0050863 158 94 0,000 0,13403053 0,13498429 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,13535734 0,13626349 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,13535734 0,1362065 ! leukocyte differentiation GO:0002521 202 96 0,000 0,13668215 0,13748213 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,13668215 0,13742468 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,13668215 0,13736727 ! detection of stimulus GO:0051606 151 96 0,000 0,13668215 0,13730992 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,13800498 0,13858096 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,13800498 0,13852314 ! hormone metabolic process GO:0042445 157 97 0,000 0,13800498 0,13846538 ! response to virus GO:0009615 160 98 0,000 0,13932582 0,13973236 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,13932582 0,13967414 ! interphase GO:0051325 213 98 0,000 0,13932582 0,13961596 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,13932582 0,13955784 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,14064469 0,14082027 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,14064469 0,1407617 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,14064469 0,14070317 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,14196158 0,14196158