pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/704-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 9,104E-13 2,19E-09 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 2,094E-09 2,519E-06 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,053E-06 8,448E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,627E-06 1,58E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 2,000 3,062E-06 1,473E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,542E-06 1,42E-03 ! regulation of protein localization GO:0032880 176 97 3,000 9,344E-06 3,212E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 2,000 1,621E-05 4,874E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,621E-05 4,332E-03 ! microvillus organization GO:0032528 7 5 1,000 1,803E-05 4,339E-03 GO:0030033|microvillus assembly, ! somatic stem cell maintenance GO:0035019 15 5 1,000 1,803E-05 3,945E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 2,234E-05 4,479E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 80 42 2,000 2,591E-05 4,795E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 2,703E-05 4,645E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 2,703E-05 4,335E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of pseudopodium assembly GO:0031274 14 6 1,000 2,703E-05 4,064E-03 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of protein transport GO:0051222 72 46 2,000 3,413E-05 4,83E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 3,413E-05 4,562E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,781E-05 4,788E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,781E-05 4,548E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 3,781E-05 4,332E-03 ! spindle checkpoint GO:0031577 15 7 1,000 3,781E-05 4,135E-03 ! negative regulation of nuclear division GO:0051784 14 7 1,000 3,781E-05 3,955E-03 GO:0045839|negative regulation of mitosis, ! ER overload response GO:0006983 12 8 1,000 5,037E-05 5,049E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 6,51E-05 6,266E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,081E-05 7,478E-03 ! lens development in camera-type eye GO:0002088 16 10 1,000 8,081E-05 7,201E-03 ! midbrain development GO:0030901 13 10 1,000 8,081E-05 6,944E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 8,786E-05 7,289E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 9,868E-05 7,914E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,104E-04 8,565E-03 ! regulation of cell projection assembly GO:0060491 30 12 1,000 1,183E-04 8,896E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,183E-04 8,626E-03 ! histone acetylation GO:0016573 26 12 1,000 1,183E-04 8,372E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,183E-04 8,133E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,628E-04 0,01088354 ! stem cell development GO:0048864 43 14 1,000 1,628E-04 0,01058939 GO:0019827|stem cell maintenance, ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,144E-04 0,01357311 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,144E-04 0,01322508 ! regulation of protein transport GO:0051223 154 87 2,000 2,293E-04 0,01378952 GO:0070201|regulation of establishment of protein localization, ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,427E-04 0,01424499 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 2,427E-04 0,01390582 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,729E-04 0,01526706 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 3,047E-04 0,01666101 ! proximal/distal pattern formation GO:0009954 32 19 1,000 3,047E-04 0,01629076 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,383E-04 0,01769208 ! stem cell differentiation GO:0048863 53 20 1,000 3,383E-04 0,01731566 ! peptidyl-serine modification GO:0018209 43 20 1,000 3,383E-04 0,01695491 ! axis specification GO:0009798 38 21 1,000 3,735E-04 0,01834137 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 3,735E-04 0,01797455 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,105E-04 0,01936761 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 4,105E-04 0,01899515 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,318E-04 0,02414105 ! osteoblast differentiation GO:0001649 60 25 1,000 5,318E-04 0,02369399 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,318E-04 0,02326319 ! somitogenesis GO:0001756 43 25 1,000 5,318E-04 0,02284778 ! embryonic pattern specification GO:0009880 44 26 1,000 5,756E-04 0,02429657 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 5,756E-04 0,02387766 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 5,756E-04 0,02347295 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 6,211E-04 0,0249068 ! protein amino acid acylation GO:0043543 55 27 1,000 6,211E-04 0,02449849 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,683E-04 0,02593509 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 7,172E-04 0,02739043 ! mesoderm formation GO:0001707 69 31 1,000 8,2E-04 0,03082747 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 8,739E-04 0,03234886 ! BMP signaling pathway GO:0030509 64 32 1,000 8,739E-04 0,03185873 ! hindbrain development GO:0030902 61 32 1,000 8,739E-04 0,03138322 ! formation of primary germ layer GO:0001704 72 33 1,000 9,295E-04 0,03288831 ! mesoderm morphogenesis GO:0048332 76 34 1,000 9,868E-04 0,03440774 ! cytokine production GO:0001816 59 35 1,000 1,046E-03 0,03594075 ! regulation of microtubule-based process GO:0032886 78 35 1,000 1,046E-03 0,03543455 ! glycogen metabolic process GO:0005977 61 37 1,000 1,168E-03 0,03904468 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 1,232E-03 0,04061426 ! glucan metabolic process GO:0044042 62 38 1,000 1,232E-03 0,04006542 GO:0006073|cellular glucan metabolic process, ! segmentation GO:0035282 67 39 1,000 1,298E-03 0,04163217 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 1,434E-03 0,04538627 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 1,504E-03 0,04699621 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 1,504E-03 0,04639369 ! epithelial cell differentiation GO:0030855 79 43 1,000 1,576E-03 0,04799955 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 1,576E-03 0,04739956 ! energy reserve metabolic process GO:0006112 74 43 1,000 1,576E-03 0,04681438 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 1,576E-03 0,04624347 ! positive regulation of DNA binding GO:0043388 73 47 1,000 1,88E-03 0,05450408 ! protein homooligomerization GO:0051260 76 47 1,000 1,88E-03 0,05385522 ! mitochondrial transport GO:0006839 82 48 1,000 1,96E-03 0,05548785 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 2,042E-03 0,0571272 ! regulation of cell projection organization GO:0031344 121 50 1,000 2,125E-03 0,05877292 ! regulation of ossification GO:0030278 117 50 1,000 2,125E-03 0,05810504 ! histone modification GO:0016570 91 50 1,000 2,125E-03 0,05745218 ! positive regulation of binding GO:0051099 78 51 1,000 2,21E-03 0,05908191 ! covalent chromatin modification GO:0016569 101 52 1,000 2,296E-03 0,06071771 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 2,474E-03 0,06470204 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 2,565E-03 0,06636456 ! gastrulation GO:0007369 112 55 1,000 2,565E-03 0,06565856 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 2,752E-03 0,06970359 ! regulation of bone remodeling GO:0046850 137 57 1,000 2,752E-03 0,06897751 ! positive regulation of cell migration GO:0030335 126 57 1,000 2,752E-03 0,0682664 ! regulation of tissue remodeling GO:0034103 140 58 1,000 2,848E-03 0,06992287 ! camera-type eye development GO:0043010 116 60 1,000 3,044E-03 0,07398844 ! mesoderm development GO:0007498 119 61 1,000 3,145E-03 0,0756665 ! regulation of mitosis GO:0007088 105 63 1,000 3,351E-03 0,07981544 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 146 64 1,000 3,456E-03 0,08151231 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 3,562E-03 0,08321197 GO:0035113|embryonic appendage morphogenesis, ! cell projection assembly GO:0030031 120 66 1,000 3,67E-03 0,08491424 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 3,78E-03 0,08661895 ! lung development GO:0030324 144 67 1,000 3,78E-03 0,08580179 ! negative regulation of kinase activity GO:0033673 131 68 1,000 3,891E-03 0,08750047 ! cell cycle checkpoint GO:0000075 137 69 1,000 4,004E-03 0,0892014 ! appendage morphogenesis GO:0035107 135 70 1,000 4,118E-03 0,09090443 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 4,118E-03 0,09007802 ! appendage development GO:0048736 136 71 1,000 4,234E-03 0,0917751 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 4,351E-03 0,09347411 ! negative regulation of transferase activity GO:0051348 140 72 1,000 4,351E-03 0,0926469 ! respiratory system development GO:0060541 153 72 1,000 4,351E-03 0,09183421 ! regulation of transcription factor activity GO:0051090 126 74 1,000 4,59E-03 0,09603498 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 4,59E-03 0,0952071 ! eye development GO:0001654 143 74 1,000 4,59E-03 0,09439336 ! negative regulation of organelle organization GO:0010639 161 78 1,000 5,086E-03 0,10370146 ! protein oligomerization GO:0051259 139 78 1,000 5,086E-03 0,10283002 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 5,214E-03 0,10453201 ! regulation of peptidase activity GO:0052547 134 79 1,000 5,214E-03 0,10366811 ! response to hypoxia GO:0001666 171 81 1,000 5,473E-03 0,10793908 ! response to oxygen levels GO:0070482 176 83 1,000 5,739E-03 0,11225487 ! regulation of DNA binding GO:0051101 155 88 1,000 6,428E-03 0,12472001 ! ossification GO:0001503 188 90 1,000 6,713E-03 0,12922117 ! regulation of cell cycle process GO:0010564 149 90 1,000 6,713E-03 0,1281956 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 6,789E-03 0,12861166 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 6,789E-03 0,12760689 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,789E-03 0,12661769 ! positive regulation of helicase activity GO:0051096 11 5 0,000 6,789E-03 0,1256437 ! neuron fate determination GO:0048664 7 5 0,000 6,789E-03 0,12468459 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,789E-03 0,12374001 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 6,789E-03 0,12280963 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 6,789E-03 0,12189314 ! polyol transport GO:0015791 12 5 0,000 6,789E-03 0,12099023 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 6,789E-03 0,1201006 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,789E-03 0,11922395 ! response to superoxide GO:0000303 10 5 0,000 6,789E-03 0,11836001 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,789E-03 0,1175085 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 6,789E-03 0,11666915 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 6,789E-03 0,11584171 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,789E-03 0,11502593 ! female meiosis GO:0007143 7 5 0,000 6,789E-03 0,11422155 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 6,789E-03 0,11342834 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,789E-03 0,11264608 ! cobalt ion transport GO:0006824 11 5 0,000 6,789E-03 0,11187453 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 6,789E-03 0,11111348 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 6,789E-03 0,11036271 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 6,789E-03 0,10962202 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,789E-03 0,10889121 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,789E-03 0,10817008 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 6,789E-03 0,10745843 ! embryonic camera-type eye development GO:0031076 10 5 0,000 6,789E-03 0,10675609 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,789E-03 0,10606287 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 6,789E-03 0,10537859 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 6,789E-03 0,10470309 ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,789E-03 0,10403619 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 6,789E-03 0,10337773 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 6,789E-03 0,10272756 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 6,789E-03 0,10208551 ! negative chemotaxis GO:0050919 14 5 0,000 6,789E-03 0,10145144 ! positive regulation of histone modification GO:0031058 5 5 0,000 6,789E-03 0,10082519 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,789E-03 0,10020663 ! sensory perception of bitter taste GO:0050913 7 5 0,000 6,789E-03 0,09959562 ! behavioral response to pain GO:0048266 9 5 0,000 6,789E-03 0,09899201 ! clathrin coat assembly GO:0048268 14 5 0,000 6,789E-03 0,09839567 ! Notch receptor processing GO:0007220 8 5 0,000 6,789E-03 0,09780648 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,789E-03 0,09722429 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 6,789E-03 0,096649 ! micturition GO:0060073 9 5 0,000 6,789E-03 0,09608048 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,789E-03 0,0955186 ! copulation GO:0007620 9 5 0,000 6,789E-03 0,09496326 ! glial cell fate commitment GO:0021781 13 5 0,000 6,789E-03 0,09441434 ! protein maturation by protein folding GO:0022417 13 5 0,000 6,789E-03 0,09387173 ! spermidine metabolic process GO:0008216 7 5 0,000 6,789E-03 0,09333532 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,789E-03 0,09280501 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,789E-03 0,09228069 ! apoptotic cell clearance GO:0043277 20 5 0,000 6,789E-03 0,09176225 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,789E-03 0,09124962 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,789E-03 0,09074267 ! grooming behavior GO:0007625 6 5 0,000 6,789E-03 0,09024133 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,789E-03 0,0897455 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 6,789E-03 0,08925509 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,789E-03 0,08877001 ! response to protozoan GO:0001562 10 5 0,000 6,789E-03 0,08829017 ! positive regulation of glycolysis GO:0045821 14 5 0,000 6,789E-03 0,08781549 ! lymph vessel development GO:0001945 10 5 0,000 6,789E-03 0,08734589 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 6,789E-03 0,08688128 ! endochondral ossification GO:0001958 16 5 0,000 6,789E-03 0,08642159 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,789E-03 0,08596674 ! parathyroid gland development GO:0060017 13 5 0,000 6,789E-03 0,08551666 ! anagen GO:0042640 6 5 0,000 6,789E-03 0,08507126 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,789E-03 0,08463047 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,789E-03 0,08419423 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 6,789E-03 0,08376247 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 6,789E-03 0,08333511 ! dorsal spinal cord development GO:0021516 7 5 0,000 6,789E-03 0,08291209 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 6,789E-03 0,08249334 ! sphingoid catabolic process GO:0046521 6 5 0,000 6,789E-03 0,0820788 ! skeletal myofibril assembly GO:0014866 10 5 0,000 6,789E-03 0,08166841 ! smooth muscle tissue development GO:0048745 28 5 0,000 6,789E-03 0,0812621 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,789E-03 0,08085981 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,789E-03 0,08046148 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,789E-03 0,08006707 ! cardiac muscle fiber development GO:0048739 10 5 0,000 6,789E-03 0,07967649 ! transepithelial chloride transport GO:0030321 9 5 0,000 6,789E-03 0,07928972 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,789E-03 0,07890667 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 6,789E-03 0,07852731 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 6,789E-03 0,07815159 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,789E-03 0,07777944 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,789E-03 0,07741081 ! histidine catabolic process GO:0006548 6 5 0,000 6,789E-03 0,07704567 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 6,789E-03 0,07668395 ! valine metabolic process GO:0006573 10 5 0,000 6,789E-03 0,07632561 ! L-serine biosynthetic process GO:0006564 6 5 0,000 6,789E-03 0,07597061 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 6,789E-03 0,0756189 ! tryptophan metabolic process GO:0006568 9 5 0,000 6,789E-03 0,07527042 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 6,789E-03 0,07492514 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 6,789E-03 0,07458302 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 6,789E-03 0,07424401 ! polyol catabolic process GO:0046174 7 5 0,000 6,789E-03 0,07390806 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 6,789E-03 0,07357514 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 6,789E-03 0,07324521 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 6,789E-03 0,07291822 ! muscle cell migration GO:0014812 8 5 0,000 6,789E-03 0,07259414 ! mitochondrial fission GO:0000266 8 5 0,000 6,789E-03 0,07227293 ! sister chromatid cohesion GO:0007062 12 5 0,000 6,789E-03 0,07195454 ! mRNA transcription GO:0009299 9 5 0,000 6,789E-03 0,07163895 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 6,789E-03 0,07132612 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 6,789E-03 0,07101601 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 6,789E-03 0,07070858 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 6,789E-03 0,0704038 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,789E-03 0,07010164 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,789E-03 0,06980206 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,789E-03 0,06950503 ! response to food GO:0032094 6 5 0,000 6,789E-03 0,06921051 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,789E-03 0,06891849 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,789E-03 0,06862891 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 6,789E-03 0,06834176 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,789E-03 0,06805701 ! paraxial mesoderm development GO:0048339 14 5 0,000 6,789E-03 0,06777461 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 6,789E-03 0,06749455 ! forebrain neuron development GO:0021884 13 5 0,000 6,789E-03 0,0672168 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,789E-03 0,06694132 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 6,789E-03 0,06666809 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,789E-03 0,06639708 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,789E-03 0,06612826 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,789E-03 0,06586162 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 6,789E-03 0,06559711 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,789E-03 0,06533473 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 6,789E-03 0,06507443 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 6,789E-03 0,0648162 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 6,789E-03 0,06456001 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 6,789E-03 0,06430583 ! basic amino acid transport GO:0015802 11 5 0,000 6,789E-03 0,06405365 ! cellular glucose homeostasis GO:0001678 5 5 0,000 6,789E-03 0,06380344 ! early endosome to late endosome transport GO:0045022 12 5 0,000 6,789E-03 0,06355518 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,789E-03 0,06330884 ! depyrimidination GO:0045008 10 5 0,000 6,789E-03 0,06306441 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,789E-03 0,06282185 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,789E-03 0,06258115 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,789E-03 0,0623423 ! zinc ion homeostasis GO:0055069 8 5 0,000 6,789E-03 0,06210525 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 6,789E-03 0,06187001 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 6,789E-03 0,06163653 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,789E-03 0,06140482 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,789E-03 0,06117484 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,789E-03 0,06094657 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 6,789E-03 0,06072001 ! peptidyl-arginine modification GO:0018195 9 5 0,000 6,789E-03 0,06049512 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,789E-03 0,06027189 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,789E-03 0,0600503 ! response to arsenic GO:0046685 10 5 0,000 6,789E-03 0,05983033 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 6,789E-03 0,05961198 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,789E-03 0,0593952 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 6,789E-03 0,05918 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 6,789E-03 0,05896636 ! response to cadmium ion GO:0046686 7 5 0,000 6,789E-03 0,05875425 ! bile acid biosynthetic process GO:0006699 6 5 0,000 6,789E-03 0,05854366 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 6,789E-03 0,05833458 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,789E-03 0,05812698 ! decidualization GO:0046697 11 5 0,000 6,789E-03 0,05792086 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 6,789E-03 0,05771619 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 6,789E-03 0,05751296 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 6,789E-03 0,05731116 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 6,789E-03 0,05711077 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 6,789E-03 0,05691178 ! base conversion or substitution editing GO:0016553 5 5 0,000 6,789E-03 0,05671417 ! neural tube patterning GO:0021532 7 5 0,000 6,789E-03 0,05651793 ! embryonic cleavage GO:0040016 6 5 0,000 6,789E-03 0,05632304 ! peroxisome fission GO:0016559 5 5 0,000 6,789E-03 0,05612949 ! histone demethylation GO:0016577 10 5 0,000 6,789E-03 0,05593726 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 6,789E-03 0,05574635 ! mitotic recombination GO:0006312 9 5 0,000 6,789E-03 0,05555674 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,789E-03 0,05536841 ! metaphase plate congression GO:0051310 7 5 0,000 6,789E-03 0,05518136 ! regulation of sterol transport GO:0032371 7 5 0,000 6,789E-03 0,05499556 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,789E-03 0,05481101 ! enteric nervous system development GO:0048484 8 5 0,000 6,789E-03 0,0546277 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 6,789E-03 0,0544456 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 6,789E-03 0,05426472 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 6,789E-03 0,05408504 ! muscle cell proliferation GO:0033002 11 5 0,000 6,789E-03 0,05390654 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,789E-03 0,05372922 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 6,789E-03 0,05355305 ! plasminogen activation GO:0031639 5 5 0,000 6,789E-03 0,05337804 ! B cell homeostasis GO:0001782 13 5 0,000 6,789E-03 0,05320417 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 6,789E-03 0,05303143 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,789E-03 0,05285981 ! metaphase GO:0051323 8 5 0,000 6,789E-03 0,05268929 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 6,789E-03 0,05251988 ! cellular response to nutrient GO:0031670 8 5 0,000 6,789E-03 0,05235154 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,789E-03 0,05218429 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 6,789E-03 0,05201809 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 6,789E-03 0,05185296 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 6,789E-03 0,05168887 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 6,789E-03 0,05152581 ! response to redox state GO:0051775 5 5 0,000 6,789E-03 0,05136378 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 6,789E-03 0,05120276 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 6,789E-03 0,05104275 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,789E-03 0,05088374 ! regulation of telomerase activity GO:0051972 6 5 0,000 6,789E-03 0,05072572 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,789E-03 0,05056867 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 6,789E-03 0,0504126 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,789E-03 0,05025748 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 6,789E-03 0,05010332 ! striatum development GO:0021756 9 5 0,000 6,789E-03 0,0499501 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 6,789E-03 0,04979781 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 6,789E-03 0,04964645 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,789E-03 0,049496 ! glial cell migration GO:0008347 11 5 0,000 6,789E-03 0,04934647 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,789E-03 0,04919784 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 6,789E-03 0,04905009 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 6,789E-03 0,04890324 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,789E-03 0,04875726 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,789E-03 0,04861215 ! neuroprotection GO:0043526 6 5 0,000 6,789E-03 0,0484679 ! neural plate development GO:0001840 8 5 0,000 6,789E-03 0,0483245 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,789E-03 0,04818195 ! regulation of sensory perception GO:0051931 7 5 0,000 6,789E-03 0,04804024 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,789E-03 0,04789936 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,789E-03 0,0477593 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 6,789E-03 0,04762006 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 6,789E-03 0,04748163 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,789E-03 0,047344 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,789E-03 0,04720717 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 6,789E-03 0,04707113 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,789E-03 0,04693587 ! spindle assembly GO:0051225 6 5 0,000 6,789E-03 0,04680138 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 6,789E-03 0,04666766 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,789E-03 0,0465347 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,789E-03 0,0464025 ! drug metabolic process GO:0017144 6 5 0,000 6,789E-03 0,04627105 ! stem cell division GO:0017145 11 5 0,000 6,789E-03 0,04614034 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,789E-03 0,04601037 ! organ regeneration GO:0031100 7 5 0,000 6,789E-03 0,04588113 ! carnitine metabolic process GO:0009437 7 5 0,000 6,789E-03 0,04575261 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 6,789E-03 0,04562481 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,789E-03 0,04549772 ! bone development GO:0060348 189 91 1,000 6,858E-03 0,04583743 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 7,453E-03 0,04967 ! forebrain development GO:0030900 188 95 1,000 7,453E-03 0,04953279 ! interphase GO:0051325 213 98 1,000 7,913E-03 0,05244748 ! skeletal muscle tissue development GO:0007519 186 99 1,000 8,069E-03 0,0533361 GO:0060538|skeletal muscle organ development, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,141E-03 0,05366414 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,141E-03 0,05351752 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 8,141E-03 0,05337169 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 8,141E-03 0,05322666 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,141E-03 0,05308242 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 8,141E-03 0,05293895 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 8,141E-03 0,05279626 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,141E-03 0,05265433 ! sleep GO:0030431 13 6 0,000 8,141E-03 0,05251317 ! response to oxygen radical GO:0000305 11 6 0,000 8,141E-03 0,05237276 ! positive regulation of axon extension GO:0045773 11 6 0,000 8,141E-03 0,0522331 ! myoblast cell fate commitment GO:0048625 16 6 0,000 8,141E-03 0,05209418 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 8,141E-03 0,051956 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 8,141E-03 0,05181855 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,141E-03 0,05168182 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,141E-03 0,05154582 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 8,141E-03 0,05141053 ! forebrain regionalization GO:0021871 8 6 0,000 8,141E-03 0,05127595 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,141E-03 0,05114207 ! male meiosis GO:0007140 7 6 0,000 8,141E-03 0,05100888 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,141E-03 0,05087639 ! response to zinc ion GO:0010043 9 6 0,000 8,141E-03 0,05074459 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,141E-03 0,05061347 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 8,141E-03 0,05048302 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 8,141E-03 0,05035324 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,141E-03 0,05022413 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,141E-03 0,05009568 ! malate metabolic process GO:0006108 11 6 0,000 8,141E-03 0,04996789 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 8,141E-03 0,04984074 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 8,141E-03 0,04971424 ! protein refolding GO:0042026 15 6 0,000 8,141E-03 0,04958838 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,141E-03 0,04946316 ! opsonization GO:0008228 8 6 0,000 8,141E-03 0,04933857 ! mating behavior GO:0007617 7 6 0,000 8,141E-03 0,0492146 ! neuron remodeling GO:0016322 15 6 0,000 8,141E-03 0,04909126 ! erythrocyte maturation GO:0043249 7 6 0,000 8,141E-03 0,04896853 ! embryonic hemopoiesis GO:0035162 14 6 0,000 8,141E-03 0,04884641 ! equilibrioception GO:0050957 14 6 0,000 8,141E-03 0,0487249 ! protein amino acid dealkylation GO:0008214 12 6 0,000 8,141E-03 0,048604 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 8,141E-03 0,04848369 ! photoreceptor cell development GO:0042461 10 6 0,000 8,141E-03 0,04836398 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 8,141E-03 0,04824486 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,141E-03 0,04812632 ! response to interferon-gamma GO:0034341 15 6 0,000 8,141E-03 0,04800836 ! toxin metabolic process GO:0009404 11 6 0,000 8,141E-03 0,04789098 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,141E-03 0,04777417 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 8,141E-03 0,04765794 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 8,141E-03 0,04754226 ! nuclear migration GO:0007097 12 6 0,000 8,141E-03 0,04742715 ! cGMP-mediated signaling GO:0019934 13 6 0,000 8,141E-03 0,04731259 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,141E-03 0,04719858 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 8,141E-03 0,04708512 ! thymic T cell selection GO:0045061 12 6 0,000 8,141E-03 0,04697221 ! protein lipoylation GO:0009249 10 6 0,000 8,141E-03 0,04685984 ! cysteine metabolic process GO:0006534 10 6 0,000 8,141E-03 0,046748 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,141E-03 0,04663669 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 8,141E-03 0,04652592 ! glutamate catabolic process GO:0006538 10 6 0,000 8,141E-03 0,04641567 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 8,141E-03 0,04630594 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 8,141E-03 0,04619673 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 8,141E-03 0,04608803 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,141E-03 0,04597984 ! hyperosmotic response GO:0006972 9 6 0,000 8,141E-03 0,04587216 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 8,141E-03 0,04576498 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 8,141E-03 0,0456583 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,141E-03 0,04555212 ! urea metabolic process GO:0019627 7 6 0,000 8,141E-03 0,04544643 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,141E-03 0,04534123 ! neutrophil activation GO:0042119 8 6 0,000 8,141E-03 0,04523652 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,141E-03 0,04513228 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 8,141E-03 0,04502853 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,141E-03 0,04492526 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 8,141E-03 0,04482245 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,141E-03 0,04472012 ! neuron apoptosis GO:0051402 9 6 0,000 8,141E-03 0,04461825 ! nucleoside salvage GO:0043174 9 6 0,000 8,141E-03 0,04451684 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 8,141E-03 0,0444159 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,141E-03 0,04431541 ! T cell mediated immunity GO:0002456 16 6 0,000 8,141E-03 0,04421538 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,141E-03 0,04411579 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 8,141E-03 0,04401665 ! carnitine transport GO:0015879 10 6 0,000 8,141E-03 0,04391796 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 8,141E-03 0,04381971 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,141E-03 0,0437219 ! positive regulation of exocytosis GO:0045921 8 6 0,000 8,141E-03 0,04362452 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 8,141E-03 0,04352758 ! 5S class rRNA transcription GO:0042791 11 6 0,000 8,141E-03 0,04343107 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,141E-03 0,04333498 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 8,141E-03 0,04323932 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 8,141E-03 0,04314408 ! sodium ion homeostasis GO:0055078 11 6 0,000 8,141E-03 0,04304926 ! establishment of spindle localization GO:0051293 12 6 0,000 8,141E-03 0,04295485 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 8,141E-03 0,04286086 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,141E-03 0,04276727 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 8,141E-03 0,0426741 ! neural nucleus development GO:0048857 14 6 0,000 8,141E-03 0,04258133 ! response to UV-C GO:0010225 11 6 0,000 8,141E-03 0,04248896 ! astrocyte development GO:0014002 15 6 0,000 8,141E-03 0,04239699 ! protein targeting to lysosome GO:0006622 10 6 0,000 8,141E-03 0,04230542 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,141E-03 0,04221425 ! interaction with symbiont GO:0051702 13 6 0,000 8,141E-03 0,04212347 ! regulation of dendrite development GO:0050773 16 6 0,000 8,141E-03 0,04203307 ! skeletal muscle contraction GO:0003009 6 6 0,000 8,141E-03 0,04194307 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 8,141E-03 0,04185344 ! response to copper ion GO:0046688 10 6 0,000 8,141E-03 0,0417642 ! response to exogenous dsRNA GO:0043330 10 6 0,000 8,141E-03 0,04167534 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 8,141E-03 0,04158686 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,141E-03 0,04149875 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 8,141E-03 0,04141102 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,141E-03 0,04132365 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 8,141E-03 0,04123666 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,141E-03 0,04115002 ! nucleoside catabolic process GO:0009164 7 6 0,000 8,141E-03 0,04106376 ! hair follicle maturation GO:0048820 7 6 0,000 8,141E-03 0,04097785 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,141E-03 0,0408923 ! Schwann cell development GO:0014044 15 6 0,000 8,141E-03 0,04080711 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 8,141E-03 0,04072227 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 8,141E-03 0,04063778 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 8,141E-03 0,04055365 ! subpallium development GO:0021544 10 6 0,000 8,141E-03 0,04046986 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 8,141E-03 0,04038642 ! histone ubiquitination GO:0016574 8 6 0,000 8,141E-03 0,04030332 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 8,141E-03 0,04022056 ! maintenance of organ identity GO:0048496 9 6 0,000 8,141E-03 0,04013814 ! G2 phase GO:0051319 16 6 0,000 8,141E-03 0,04005606 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 8,141E-03 0,03997431 ! establishment of planar polarity GO:0001736 7 6 0,000 8,141E-03 0,03989289 ! regulation of mast cell activation GO:0033003 12 6 0,000 8,141E-03 0,03981181 ! membrane to membrane docking GO:0022614 14 6 0,000 8,141E-03 0,03973106 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,141E-03 0,03965063 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 8,141E-03 0,03957053 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,141E-03 0,03949075 ! receptor internalization GO:0031623 10 6 0,000 8,141E-03 0,03941129 ! neutrophil homeostasis GO:0001780 10 6 0,000 8,141E-03 0,03933215 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,141E-03 0,03925333 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 8,141E-03 0,03917482 ! protein deubiquitination GO:0016579 14 6 0,000 8,141E-03 0,03909663 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 8,141E-03 0,03901875 ! protein destabilization GO:0031648 9 6 0,000 8,141E-03 0,03894118 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 8,141E-03 0,03886391 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 8,141E-03 0,03878695 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 8,141E-03 0,0387103 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 8,141E-03 0,03863395 ! progesterone metabolic process GO:0042448 10 6 0,000 8,141E-03 0,0385579 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 8,141E-03 0,03848214 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 8,141E-03 0,03840669 ! negative regulation of axon extension GO:0030517 21 6 0,000 8,141E-03 0,03833153 ! removal of superoxide radicals GO:0019430 11 6 0,000 8,141E-03 0,03825666 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,141E-03 0,03818209 ! determination of adult lifespan GO:0008340 15 6 0,000 8,141E-03 0,0381078 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 8,141E-03 0,03803381 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 8,141E-03 0,0379601 ! cerebellar cortex formation GO:0021697 8 6 0,000 8,141E-03 0,03788668 ! catecholamine transport GO:0051937 9 6 0,000 8,141E-03 0,03781354 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 8,141E-03 0,03774068 ! sensory cilium assembly GO:0035058 10 6 0,000 8,141E-03 0,0376681 ! organ or tissue specific immune response GO:0002251 7 6 0,000 8,141E-03 0,0375958 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 8,141E-03 0,03752378 ! maternal placenta development GO:0001893 12 6 0,000 8,141E-03 0,03745203 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 8,141E-03 0,03738056 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,141E-03 0,03730936 ! negative regulation of B cell activation GO:0050869 13 6 0,000 8,141E-03 0,03723842 ! protein amino acid prenylation GO:0018346 16 6 0,000 8,141E-03 0,03716776 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 8,141E-03 0,03709737 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 8,141E-03 0,03702724 ! positive regulation of coagulation GO:0050820 12 6 0,000 8,141E-03 0,03695738 ! cell cycle arrest GO:0007050 213 100 1,000 8,227E-03 0,03727606 ! tRNA transcription GO:0009304 14 7 0,000 9,492E-03 0,04292635 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 9,492E-03 0,04284581 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 9,492E-03 0,04276558 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,492E-03 0,04268564 ! regulation of helicase activity GO:0051095 15 7 0,000 9,492E-03 0,04260601 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 9,492E-03 0,04252667 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 9,492E-03 0,04244762 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,492E-03 0,04236887 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 9,492E-03 0,04229041 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,492E-03 0,04221224 ! prostate gland development GO:0030850 13 7 0,000 9,492E-03 0,04213435 ! nucleotide-sugar transport GO:0015780 12 7 0,000 9,492E-03 0,04205676 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,492E-03 0,04197945 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,492E-03 0,04190242 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 9,492E-03 0,04182568 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,492E-03 0,04174921 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 9,492E-03 0,04167303 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 9,492E-03 0,04159712 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 9,492E-03 0,04152149 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 9,492E-03 0,04144613 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,492E-03 0,04137105 ! SMAD protein complex assembly GO:0007183 12 7 0,000 9,492E-03 0,04129624 ! glycolipid transport GO:0046836 10 7 0,000 9,492E-03 0,0412217 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,492E-03 0,04114742 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 9,492E-03 0,04107342 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,492E-03 0,04099968 ! actin-myosin filament sliding GO:0033275 11 7 0,000 9,492E-03 0,0409262 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 9,492E-03 0,04085299 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 9,492E-03 0,04078003 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 9,492E-03 0,04070734 ! mRNA stabilization GO:0048255 18 7 0,000 9,492E-03 0,04063491 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 9,492E-03 0,04056273 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 9,492E-03 0,04049081 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 9,492E-03 0,04041915 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 9,492E-03 0,04034774 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 9,492E-03 0,04027658 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,492E-03 0,04020567 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,492E-03 0,04013501 ! lipoprotein transport GO:0042953 14 7 0,000 9,492E-03 0,04006459 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 9,492E-03 0,03999443 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 9,492E-03 0,03992451 ! rhythmic behavior GO:0007622 15 7 0,000 9,492E-03 0,03985483 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 9,492E-03 0,0397854 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 9,492E-03 0,03971621 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 9,492E-03 0,03964726 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,492E-03 0,03957854 ! regulation of odontogenesis GO:0042481 13 7 0,000 9,492E-03 0,03951007 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,492E-03 0,03944183 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 9,492E-03 0,03937383 ! mechanosensory behavior GO:0007638 14 7 0,000 9,492E-03 0,03930606 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 9,492E-03 0,03923852 ! positive regulation of isotype switching GO:0045830 15 7 0,000 9,492E-03 0,03917122 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 9,492E-03 0,03910414 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,492E-03 0,0390373 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,492E-03 0,03897068 ! spinal cord patterning GO:0021511 13 7 0,000 9,492E-03 0,03890429 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 9,492E-03 0,03883813 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,492E-03 0,03877219 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 9,492E-03 0,03870647 ! adrenal gland development GO:0030325 17 7 0,000 9,492E-03 0,03864098 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 9,492E-03 0,03857571 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 9,492E-03 0,03851066 ! ovulation GO:0030728 9 7 0,000 9,492E-03 0,03844582 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 9,492E-03 0,03838121 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 9,492E-03 0,03831681 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 9,492E-03 0,03825263 ! microtubule nucleation GO:0007020 20 7 0,000 9,492E-03 0,03818866 ! proline biosynthetic process GO:0006561 10 7 0,000 9,492E-03 0,03812491 ! thyroid hormone generation GO:0006590 13 7 0,000 9,492E-03 0,03806137 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 9,492E-03 0,03799804 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 9,492E-03 0,03793492 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 9,492E-03 0,03787201 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,492E-03 0,0378093 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 9,492E-03 0,03774681 ! galactose metabolic process GO:0006012 13 7 0,000 9,492E-03 0,03768452 ! vesicle fusion GO:0006906 17 7 0,000 9,492E-03 0,03762244 ! response to dietary excess GO:0002021 8 7 0,000 9,492E-03 0,03756056 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,492E-03 0,03749888 ! intracellular pH reduction GO:0051452 11 7 0,000 9,492E-03 0,03743741 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,492E-03 0,03737614 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 9,492E-03 0,03731506 ! organ growth GO:0035265 15 7 0,000 9,492E-03 0,03725419 ! purine salvage GO:0043101 10 7 0,000 9,492E-03 0,03719352 ! nucleoside transport GO:0015858 8 7 0,000 9,492E-03 0,03713304 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 9,492E-03 0,03707276 ! parturition GO:0007567 14 7 0,000 9,492E-03 0,03701267 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 9,492E-03 0,03695278 ! rRNA modification GO:0000154 14 7 0,000 9,492E-03 0,03689308 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 9,492E-03 0,03683358 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 9,492E-03 0,03677427 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 9,492E-03 0,03671514 ! macrophage differentiation GO:0030225 11 7 0,000 9,492E-03 0,03665621 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 9,492E-03 0,03659747 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,492E-03 0,03653891 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 9,492E-03 0,03648054 ! hyaluronan metabolic process GO:0030212 8 7 0,000 9,492E-03 0,03642236 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 9,492E-03 0,03636436 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,492E-03 0,03630655 ! fibrinolysis GO:0042730 10 7 0,000 9,492E-03 0,03624892 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 9,492E-03 0,03619147 ! eating behavior GO:0042755 7 7 0,000 9,492E-03 0,03613421 ! B cell lineage commitment GO:0002326 21 7 0,000 9,492E-03 0,03607712 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,492E-03 0,03602022 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 9,492E-03 0,03596349 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 9,492E-03 0,03590695 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,492E-03 0,03585058 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 9,492E-03 0,03579439 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,492E-03 0,03573837 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 9,492E-03 0,03568253 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 9,492E-03 0,03562686 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 9,492E-03 0,03557137 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 9,492E-03 0,03551605 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,492E-03 0,0354609 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 9,492E-03 0,03540592 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,492E-03 0,03535111 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,492E-03 0,03529647 ! regulation of meiosis GO:0040020 12 7 0,000 9,492E-03 0,035242 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 9,492E-03 0,0351877 ! T cell lineage commitment GO:0002360 16 7 0,000 9,492E-03 0,03513357 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 9,492E-03 0,0350796 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,492E-03 0,0350258 ! oxygen homeostasis GO:0032364 12 7 0,000 9,492E-03 0,03497216 ! transcription termination GO:0006353 13 7 0,000 9,492E-03 0,03491868 ! response to tumor cell GO:0002347 13 7 0,000 9,492E-03 0,03486537 ! regulation of respiratory burst GO:0060263 11 7 0,000 9,492E-03 0,03481222 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,492E-03 0,03475924 ! anaphase GO:0051322 17 7 0,000 9,492E-03 0,03470641 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 9,492E-03 0,03465375 ! axonal fasciculation GO:0007413 18 7 0,000 9,492E-03 0,03460124 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 9,492E-03 0,03454889 ! peptidyl-threonine modification GO:0018210 25 7 0,000 9,492E-03 0,03449671 ! diuresis GO:0030146 12 7 0,000 9,492E-03 0,03444467 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,492E-03 0,0343928 ! thiamin metabolic process GO:0006772 7 7 0,000 9,492E-03 0,03434108 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,492E-03 0,03428952 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 9,492E-03 0,03423811 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 9,492E-03 0,03418686 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,492E-03 0,03413575 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 9,492E-03 0,0340848 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 9,492E-03 0,03403401 ! melanin biosynthetic process GO:0042438 8 7 0,000 9,492E-03 0,03398336 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 9,492E-03 0,03393287 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,492E-03 0,03388252 ! glycolipid catabolic process GO:0019377 15 7 0,000 9,492E-03 0,03383232 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,492E-03 0,03378228 ! lymph node development GO:0048535 10 7 0,000 9,492E-03 0,03373238 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 9,492E-03 0,03368262 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 9,492E-03 0,03363302 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 9,492E-03 0,03358356 ! endosome to lysosome transport GO:0008333 11 7 0,000 9,492E-03 0,03353424 ! protein modification by small protein removal GO:0070646 16 7 0,000 9,492E-03 0,03348507 ! adult feeding behavior GO:0008343 9 7 0,000 9,492E-03 0,03343605 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 9,492E-03 0,03338716 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 9,492E-03 0,03333842 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,492E-03 0,03328982 ! muscle adaptation GO:0043500 14 7 0,000 9,492E-03 0,03324137 ! embryonic heart tube development GO:0035050 10 7 0,000 9,492E-03 0,03319305 ! retina homeostasis GO:0001895 12 7 0,000 9,492E-03 0,03314488 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 9,492E-03 0,03309684 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 9,492E-03 0,03304894 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 9,492E-03 0,03300118 ! protein prenylation GO:0018342 18 7 0,000 9,492E-03 0,03295356 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 9,492E-03 0,03290608 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 9,492E-03 0,03285873 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 9,492E-03 0,03281152 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01084036 0,03742024 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01084036 0,03736663 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01084036 0,03731318 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01084036 0,03725987 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01084036 0,03720672 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01084036 0,03715372 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01084036 0,03710087 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01084036 0,03704817 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01084036 0,03699562 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01084036 0,03694322 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01084036 0,03689096 ! meiotic prophase I GO:0007128 13 8 0,000 0,01084036 0,03683886 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01084036 0,0367869 ! oligopeptide transport GO:0006857 15 8 0,000 0,01084036 0,03673508 ! UTP metabolic process GO:0046051 8 8 0,000 0,01084036 0,03668342 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01084036 0,0366319 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01084036 0,03658052 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01084036 0,03652929 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01084036 0,0364782 ! succinate metabolic process GO:0006105 14 8 0,000 0,01084036 0,03642725 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01084036 0,03637644 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01084036 0,03632578 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01084036 0,03627526 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01084036 0,03622488 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01084036 0,03617463 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01084036 0,03612453 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01084036 0,03607456 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01084036 0,03602474 ! reflex GO:0060004 16 8 0,000 0,01084036 0,03597505 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01084036 0,0359255 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01084036 0,03587608 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01084036 0,0358268 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01084036 0,03577765 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01084036 0,03572864 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01084036 0,03567977 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01084036 0,03563102 ! pigment granule organization GO:0048753 16 8 0,000 0,01084036 0,03558241 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01084036 0,03553394 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01084036 0,03548559 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01084036 0,03543738 ! histidine metabolic process GO:0006547 16 8 0,000 0,01084036 0,03538929 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01084036 0,03534134 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01084036 0,03529352 ! glycine catabolic process GO:0006546 13 8 0,000 0,01084036 0,03524582 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01084036 0,03519826 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01084036 0,03515082 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01084036 0,03510351 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01084036 0,03505633 ! melanin metabolic process GO:0006582 15 8 0,000 0,01084036 0,03500928 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01084036 0,03496235 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01084036 0,03491554 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01084036 0,03486886 ! macrophage activation GO:0042116 12 8 0,000 0,01084036 0,03482231 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01084036 0,03477588 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01084036 0,03472957 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01084036 0,03468339 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01084036 0,03463733 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01084036 0,03459139 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01084036 0,03454558 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01084036 0,03449988 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01084036 0,03445431 ! osteoblast development GO:0002076 16 8 0,000 0,01084036 0,03440885 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01084036 0,03436352 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01084036 0,0343183 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01084036 0,03427321 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01084036 0,03422823 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01084036 0,03418337 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01084036 0,03413863 ! response to UV-B GO:0010224 16 8 0,000 0,01084036 0,034094 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01084036 0,03404949 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01084036 0,0340051 ! intermediate filament organization GO:0045109 12 8 0,000 0,01084036 0,03396082 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01084036 0,03391666 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01084036 0,03387261 ! cellular extravasation GO:0045123 12 8 0,000 0,01084036 0,03382868 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01084036 0,03378486 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01084036 0,03374115 ! response to antibiotic GO:0046677 11 8 0,000 0,01084036 0,03369756 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01084036 0,03365408 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01084036 0,03361071 ! DNA topological change GO:0006265 12 8 0,000 0,01084036 0,03356745 ! response to tropane GO:0014073 15 8 0,000 0,01084036 0,03352431 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01084036 0,03348127 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01084036 0,03343835 ! melanosome transport GO:0032402 13 8 0,000 0,01084036 0,03339553 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,01084036 0,03335283 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01084036 0,03331023 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01084036 0,03326774 ! mast cell activation GO:0045576 14 8 0,000 0,01084036 0,03322536 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01084036 0,03318309 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01084036 0,03314093 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01084036 0,03309887 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01084036 0,03305692 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01084036 0,03301508 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01084036 0,03297334 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01084036 0,0329317 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01084036 0,03289018 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01084036 0,03284875 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01084036 0,03280743 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01084036 0,03276622 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01084036 0,03272511 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01084036 0,0326841 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01084036 0,03264319 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01084036 0,03260239 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01084036 0,03256169 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01084036 0,03252108 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01084036 0,03248059 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01084036 0,03244019 ! hormone catabolic process GO:0042447 17 8 0,000 0,01084036 0,03239989 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01084036 0,03235969 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01084036 0,03231959 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01084036 0,03227959 ! ATP catabolic process GO:0006200 11 8 0,000 0,01084036 0,03223969 ! blastocyst growth GO:0001832 19 8 0,000 0,01084036 0,03219989 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01084036 0,03216019 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01084036 0,03212058 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01084036 0,03208107 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01084036 0,03204166 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01084036 0,03200234 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01084036 0,03196313 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01084036 0,031924 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01084036 0,03188498 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01084036 0,03184604 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01084036 0,03180721 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01084036 0,03176847 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01084036 0,03172982 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01084036 0,03169126 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01084036 0,0316528 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01084036 0,03161444 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01084036 0,03157616 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01084036 0,03153798 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01218732 0,03541388 ! axon extension GO:0048675 15 9 0,000 0,01218732 0,03537116 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01218732 0,03532854 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01218732 0,03528603 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01218732 0,03524362 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01218732 0,03520131 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01218732 0,0351591 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01218732 0,03511699 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01218732 0,03507499 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01218732 0,03503308 ! phosphate transport GO:0006817 19 9 0,000 0,01218732 0,03499128 ! reproductive behavior GO:0019098 19 9 0,000 0,01218732 0,03494957 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01218732 0,03490796 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01218732 0,03486646 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01218732 0,03482505 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01218732 0,03478374 ! GTP metabolic process GO:0046039 9 9 0,000 0,01218732 0,03474252 ! RNA methylation GO:0001510 15 9 0,000 0,01218732 0,03470141 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01218732 0,03466039 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01218732 0,03461947 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01218732 0,03457864 ! artery development GO:0060840 24 9 0,000 0,01218732 0,03453792 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01218732 0,03449728 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01218732 0,03445675 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01218732 0,0344163 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01218732 0,03437596 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01218732 0,0343357 ! chemosensory behavior GO:0007635 20 9 0,000 0,01218732 0,03429554 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01218732 0,03425548 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01218732 0,03421551 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01218732 0,03417563 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01218732 0,03413584 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01218732 0,03409615 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01218732 0,03405655 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01218732 0,03401704 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01218732 0,03397762 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01218732 0,0339383 ! protein targeting to ER GO:0045047 22 9 0,000 0,01218732 0,03389906 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01218732 0,03385992 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01218732 0,03382087 ! T cell selection GO:0045058 23 9 0,000 0,01218732 0,0337819 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01218732 0,03374303 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01218732 0,03370424 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01218732 0,03366555 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01218732 0,03362694 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01218732 0,03358842 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01218732 0,03354999 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01218732 0,03351165 ! mannose metabolic process GO:0006013 13 9 0,000 0,01218732 0,03347339 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01218732 0,03343522 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01218732 0,03339714 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01218732 0,03335915 ! receptor clustering GO:0043113 18 9 0,000 0,01218732 0,03332124 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01218732 0,03328342 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01218732 0,03324568 ! ruffle organization GO:0031529 15 9 0,000 0,01218732 0,03320803 ! retinol metabolic process GO:0042572 18 9 0,000 0,01218732 0,03317046 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01218732 0,03313298 ! behavioral fear response GO:0001662 22 9 0,000 0,01218732 0,03309559 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01218732 0,03305828 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01218732 0,03302105 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01218732 0,0329839 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01218732 0,03294684 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01218732 0,03290987 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01218732 0,03287297 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01218732 0,03283616 ! segment specification GO:0007379 13 9 0,000 0,01218732 0,03279943 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01218732 0,03276278 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01218732 0,03272622 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01218732 0,03268973 ! response to amine stimulus GO:0014075 13 9 0,000 0,01218732 0,03265333 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01218732 0,03261701 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01218732 0,03258077 ! erythrocyte development GO:0048821 15 9 0,000 0,01218732 0,03254461 ! gas homeostasis GO:0033483 16 9 0,000 0,01218732 0,03250853 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01218732 0,03247252 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01218732 0,0324366 ! renal water homeostasis GO:0003091 14 9 0,000 0,01218732 0,03240076 ! postreplication repair GO:0006301 22 9 0,000 0,01218732 0,032365 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01218732 0,03232932 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01218732 0,03229371 ! icosanoid secretion GO:0032309 15 9 0,000 0,01218732 0,03225818 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01218732 0,03222274 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01218732 0,03218737 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01218732 0,03215207 ! regulation of cell division GO:0051302 15 9 0,000 0,01218732 0,03211686 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01218732 0,03208172 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01218732 0,03204666 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01218732 0,03201167 ! sterol catabolic process GO:0016127 11 9 0,000 0,01218732 0,03197676 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01218732 0,03194193 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01218732 0,03190717 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01218732 0,03187249 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01218732 0,03183788 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01218732 0,03180335 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01218732 0,03176889 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01218732 0,03173451 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01218732 0,03170021 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01218732 0,03166597 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01218732 0,03163181 ! purine base metabolic process GO:0006144 21 9 0,000 0,01218732 0,03159773 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01218732 0,03156371 ! pigment granule transport GO:0051904 17 9 0,000 0,01218732 0,03152977 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01218732 0,03149591 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01218732 0,03146211 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01218732 0,03142839 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01218732 0,03139474 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01218732 0,03136117 ! mitochondrion localization GO:0051646 15 9 0,000 0,01218732 0,03132766 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01353249 0,03474831 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01353249 0,03471126 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01353249 0,0346743 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01353249 0,03463741 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01353249 0,0346006 ! synapsis GO:0007129 13 10 0,000 0,01353249 0,03456387 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01353249 0,03452722 ! N-glycan processing GO:0006491 20 10 0,000 0,01353249 0,03449064 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01353249 0,03445414 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01353249 0,03441772 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01353249 0,03438138 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01353249 0,03434511 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01353249 0,03430892 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01353249 0,0342728 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01353249 0,03423677 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01353249 0,0342008 ! androgen metabolic process GO:0008209 17 10 0,000 0,01353249 0,03416492 ! phospholipid efflux GO:0033700 16 10 0,000 0,01353249 0,0341291 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01353249 0,03409337 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01353249 0,0340577 ! lung alveolus development GO:0048286 26 10 0,000 0,01353249 0,03402212 ! pathogenesis GO:0009405 13 10 0,000 0,01353249 0,0339866 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01353249 0,03395116 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01353249 0,0339158 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01353249 0,0338805 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01353249 0,03384529 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01353249 0,03381014 ! endoderm development GO:0007492 16 10 0,000 0,01353249 0,03377507 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01353249 0,03374007 ! arginine catabolic process GO:0006527 13 10 0,000 0,01353249 0,03370514 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01353249 0,03367028 ! proline metabolic process GO:0006560 13 10 0,000 0,01353249 0,0336355 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01353249 0,03360079 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01353249 0,03356615 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01353249 0,03353158 ! V(D)J recombination GO:0033151 28 10 0,000 0,01353249 0,03349708 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01353249 0,03346266 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01353249 0,0334283 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01353249 0,03339401 ! B cell proliferation GO:0042100 18 10 0,000 0,01353249 0,0333598 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01353249 0,03332565 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01353249 0,03329158 ! multicellular organism growth GO:0035264 18 10 0,000 0,01353249 0,03325757 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01353249 0,03322364 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01353249 0,03318977 ! epithelial cell development GO:0002064 20 10 0,000 0,01353249 0,03315597 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01353249 0,03312224 ! macroautophagy GO:0016236 17 10 0,000 0,01353249 0,03308858 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01353249 0,03305499 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01353249 0,03302146 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01353249 0,03298801 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01353249 0,03295462 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01353249 0,0329213 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01353249 0,03288804 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01353249 0,03285486 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01353249 0,03282174 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01353249 0,03278869 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01353249 0,0327557 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01353249 0,03272278 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01353249 0,03268992 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01353249 0,03265714 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01353249 0,03262441 ! response to dsRNA GO:0043331 20 10 0,000 0,01353249 0,03259176 ! DNA ligation GO:0006266 19 10 0,000 0,01353249 0,03255916 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01353249 0,03252664 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01353249 0,03249418 ! melanosome localization GO:0032400 16 10 0,000 0,01353249 0,03246178 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01353249 0,03242945 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01353249 0,03239718 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01353249 0,03236497 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01353249 0,03233283 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01353249 0,03230076 ! mRNA cleavage GO:0006379 17 10 0,000 0,01353249 0,03226875 ! protein sumoylation GO:0016925 15 10 0,000 0,01353249 0,0322368 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01353249 0,03220491 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01353249 0,03217309 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01353249 0,03214133 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01353249 0,03210963 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01353249 0,03207799 ! salivary gland development GO:0007431 27 10 0,000 0,01353249 0,03204642 ! prophase GO:0051324 15 10 0,000 0,01353249 0,03201491 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01353249 0,03198346 ! apical protein localization GO:0045176 15 10 0,000 0,01353249 0,03195207 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01353249 0,03192075 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01353249 0,03188949 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01353249 0,03185828 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01353249 0,03182714 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01353249 0,03179606 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01353249 0,03176504 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01353249 0,03173408 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01353249 0,03170318 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01353249 0,03167234 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01353249 0,03164156 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01353249 0,03161084 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01353249 0,03158018 ! oocyte development GO:0048599 17 10 0,000 0,01353249 0,03154958 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01353249 0,03151904 ! blastocyst formation GO:0001825 17 10 0,000 0,01353249 0,03148855 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01353249 0,03145813 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01353249 0,03142776 ! activation of innate immune response GO:0002218 12 10 0,000 0,01353249 0,03139746 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01353249 0,03136721 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01353249 0,03133702 ! response to nicotine GO:0035094 20 10 0,000 0,01353249 0,03130689 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01353249 0,03127681 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01353249 0,0312468 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01353249 0,03121684 ! localization within membrane GO:0051668 20 10 0,000 0,01353249 0,03118694 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01487587 0,03425008 ! respiratory burst GO:0045730 17 11 0,000 0,01487587 0,03421734 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01487587 0,03418466 ! neuron fate specification GO:0048665 17 11 0,000 0,01487587 0,03415204 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01487587 0,03411948 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01487587 0,03408699 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01487587 0,03405456 ! thyroid gland development GO:0030878 26 11 0,000 0,01487587 0,03402219 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01487587 0,03398988 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01487587 0,03395763 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01487587 0,03392544 ! response to pain GO:0048265 24 11 0,000 0,01487587 0,03389331 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01487587 0,03386125 ! T cell proliferation GO:0042098 26 11 0,000 0,01487587 0,03382924 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01487587 0,0337973 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01487587 0,03376541 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01487587 0,03373359 ! bone resorption GO:0045453 16 11 0,000 0,01487587 0,03370183 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01487587 0,03367012 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01487587 0,03363848 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01487587 0,03360689 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01487587 0,03357536 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01487587 0,0335439 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01487587 0,03351249 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01487587 0,03348114 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01487587 0,03344985 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01487587 0,03341862 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01487587 0,03338744 ! lipid digestion GO:0044241 18 11 0,000 0,01487587 0,03335633 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01487587 0,03332527 ! UV protection GO:0009650 19 11 0,000 0,01487587 0,03329427 ! adult heart development GO:0007512 14 11 0,000 0,01487587 0,03326333 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01487587 0,03323244 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01487587 0,03320161 ! temperature homeostasis GO:0001659 17 11 0,000 0,01487587 0,03317084 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01487587 0,03314013 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01487587 0,03310947 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01487587 0,03307887 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01487587 0,03304833 ! regulation of organ growth GO:0046620 13 11 0,000 0,01487587 0,03301784 ! pigment granule localization GO:0051875 20 11 0,000 0,01487587 0,03298741 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01487587 0,03295703 ! vasoconstriction GO:0042310 18 11 0,000 0,01487587 0,03292671 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01487587 0,03289645 ! embryonic axis specification GO:0000578 18 11 0,000 0,01487587 0,03286624 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01487587 0,03283609 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01487587 0,03280599 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01487587 0,03277595 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01487587 0,03274596 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01487587 0,03271603 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01487587 0,03268615 ! zymogen activation GO:0031638 15 11 0,000 0,01487587 0,03265633 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01487587 0,03262656 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01487587 0,03259685 ! nucleosome positioning GO:0016584 15 11 0,000 0,01487587 0,03256719 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01487587 0,03253758 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01487587 0,03250803 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01487587 0,03247853 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01487587 0,03244908 ! acid secretion GO:0046717 18 11 0,000 0,01487587 0,03241969 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01487587 0,03239035 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01487587 0,03236107 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01487587 0,03233183 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01487587 0,03230265 ! oocyte differentiation GO:0009994 18 11 0,000 0,01487587 0,03227352 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01487587 0,03224445 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01487587 0,03221543 ! cholesterol efflux GO:0033344 19 11 0,000 0,01487587 0,03218646 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01487587 0,03215754 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01487587 0,03212867 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01487587 0,03209986 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01487587 0,03207109 ! embryonic gut development GO:0048566 15 11 0,000 0,01487587 0,03204238 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01487587 0,03201372 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01487587 0,03198511 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01487587 0,03195655 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01487587 0,03192805 ! defense response to fungus GO:0050832 13 11 0,000 0,01487587 0,03189959 ! developmental induction GO:0031128 19 11 0,000 0,01487587 0,03187118 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01487587 0,03184283 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01487587 0,03181452 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01487587 0,03178627 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01487587 0,03175806 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01487587 0,03172991 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01487587 0,03170181 ! nucleus localization GO:0051647 19 11 0,000 0,01487587 0,03167375 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01487587 0,03164575 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01621746 0,03446927 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01621746 0,03443885 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01621746 0,03440848 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01621746 0,03437817 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01621746 0,0343479 ! virus-host interaction GO:0019048 29 12 0,000 0,01621746 0,03431769 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01621746 0,03428754 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01621746 0,03425744 ! cartilage condensation GO:0001502 20 12 0,000 0,01621746 0,03422738 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01621746 0,03419739 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01621746 0,03416744 ! protein complex disassembly GO:0043241 27 12 0,000 0,01621746 0,03413755 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01621746 0,03410771 ! hippocampus development GO:0021766 26 12 0,000 0,01621746 0,03407792 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01621746 0,03404818 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01621746 0,0340185 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01621746 0,03398887 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01621746 0,03395929 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01621746 0,03392976 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01621746 0,03390028 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01621746 0,03387085 ! drug transport GO:0015893 16 12 0,000 0,01621746 0,03384147 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01621746 0,03381215 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01621746 0,03378287 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01621746 0,03375365 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01621746 0,03372448 ! focal adhesion formation GO:0048041 35 12 0,000 0,01621746 0,03369535 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01621746 0,03366628 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01621746 0,03363726 ! forebrain cell migration GO:0021885 21 12 0,000 0,01621746 0,03360828 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01621746 0,03357936 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01621746 0,03355049 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01621746 0,03352167 ! entry into host cell GO:0030260 32 12 0,000 0,01621746 0,03349289 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,01621746 0,03346417 ! monoamine transport GO:0015844 18 12 0,000 0,01621746 0,03343549 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01621746 0,03340687 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01621746 0,03337829 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01621746 0,03334976 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01621746 0,03332128 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01621746 0,03329285 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01621746 0,03326447 ! protein homotetramerization GO:0051289 21 12 0,000 0,01621746 0,03323613 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01621746 0,03320785 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01621746 0,03317961 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01621746 0,03315142 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01621746 0,03312328 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01621746 0,03309518 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01621746 0,03306713 ! cranial nerve development GO:0021545 20 12 0,000 0,01621746 0,03303914 ! fucose catabolic process GO:0019317 22 12 0,000 0,01621746 0,03301118 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01621746 0,03298328 ! histone methylation GO:0016571 26 12 0,000 0,01621746 0,03295542 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01621746 0,03292761 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01621746 0,03289985 ! gland morphogenesis GO:0022612 29 12 0,000 0,01621746 0,03287213 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01621746 0,03284446 ! T cell homeostasis GO:0043029 25 12 0,000 0,01621746 0,03281684 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01621746 0,03278926 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01621746 0,03276173 ! spleen development GO:0048536 22 12 0,000 0,01621746 0,03273424 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01621746 0,03270681 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01621746 0,03267941 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01621746 0,03265207 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01621746 0,03262476 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01621746 0,03259751 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01621746 0,0325703 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01621746 0,03254313 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01621746 0,03251602 ! response to cold GO:0009409 17 12 0,000 0,01621746 0,03248894 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01621746 0,03246191 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01621746 0,03243493 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01755728 0,03508539 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01755728 0,03505627 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01755728 0,03502721 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01755728 0,03499819 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01755728 0,03496921 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01755728 0,03494029 ! lipid localization GO:0010876 28 13 0,000 0,01755728 0,03491141 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01755728 0,03488258 ! organelle fusion GO:0048284 32 13 0,000 0,01755728 0,0348538 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01755728 0,03482507 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01755728 0,03479638 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01755728 0,03476774 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01755728 0,03473915 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01755728 0,03471061 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01755728 0,03468211 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01755728 0,03465366 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01755728 0,03462525 ! methionine metabolic process GO:0006555 27 13 0,000 0,01755728 0,0345969 ! plasma membrane organization GO:0007009 24 13 0,000 0,01755728 0,03456858 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01755728 0,03454032 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01755728 0,0345121 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01755728 0,03448393 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01755728 0,0344558 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01755728 0,03442772 ! response to X-ray GO:0010165 25 13 0,000 0,01755728 0,03439968 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01755728 0,03437169 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01755728 0,03434375 ! exocrine system development GO:0035272 32 13 0,000 0,01755728 0,03431585 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01755728 0,034288 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01755728 0,03426019 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01755728 0,03423242 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01755728 0,0342047 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01755728 0,03417703 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01755728 0,0341494 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01755728 0,03412182 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01755728 0,03409428 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01755728 0,03406678 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01755728 0,03403933 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01755728 0,03401192 ! ribosome assembly GO:0042255 17 13 0,000 0,01755728 0,03398456 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,01755728 0,03395724 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01755728 0,03392997 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01755728 0,03390274 ! chromatin silencing GO:0006342 26 13 0,000 0,01755728 0,03387555 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01755728 0,03384841 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01755728 0,0338213 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01755728 0,03379425 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01755728 0,03376723 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01755728 0,03374026 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01755728 0,03371334 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01755728 0,03368645 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01755728 0,03365961 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01755728 0,03363281 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01755728 0,03360605 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01755728 0,03357934 ! embryonic placenta development GO:0001892 23 13 0,000 0,01755728 0,03355267 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01755728 0,03352604 ! insulin secretion GO:0030073 23 13 0,000 0,01755728 0,03349945 ! actin filament polymerization GO:0030041 24 13 0,000 0,01755728 0,03347291 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01755728 0,03344641 ! acrosome reaction GO:0007340 18 13 0,000 0,01755728 0,03341994 ! rRNA transcription GO:0009303 25 14 0,000 0,01889531 0,03593843 ! lactation GO:0007595 26 14 0,000 0,01889531 0,03591005 ! reproductive cellular process GO:0048610 20 14 0,000 0,01889531 0,0358817 ! tRNA modification GO:0006400 20 14 0,000 0,01889531 0,03585341 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01889531 0,03582515 ! regulation of S phase GO:0033261 23 14 0,000 0,01889531 0,03579694 ! water transport GO:0006833 21 14 0,000 0,01889531 0,03576878 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01889531 0,03574066 ! non-recombinational repair GO:0000726 25 14 0,000 0,01889531 0,03571258 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01889531 0,03568455 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01889531 0,03565656 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01889531 0,03562862 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01889531 0,03560072 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01889531 0,03557286 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01889531 0,03554505 ! palate development GO:0060021 31 14 0,000 0,01889531 0,03551728 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01889531 0,03548955 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01889531 0,03546187 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01889531 0,03543423 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01889531 0,03540663 ! arginine metabolic process GO:0006525 17 14 0,000 0,01889531 0,03537908 ! regulation of heart rate GO:0002027 24 14 0,000 0,01889531 0,03535157 ! organic alcohol transport GO:0015850 29 14 0,000 0,01889531 0,0353241 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01889531 0,03529668 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01889531 0,03526929 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01889531 0,03524195 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01889531 0,03521465 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01889531 0,0351874 ! L-amino acid transport GO:0015807 30 14 0,000 0,01889531 0,03516018 ! bone mineralization GO:0030282 17 14 0,000 0,01889531 0,03513301 ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01889531 0,03510588 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01889531 0,03507879 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01889531 0,03505175 ! cerebellum development GO:0021549 21 14 0,000 0,01889531 0,03502474 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01889531 0,03499778 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01889531 0,03497086 ! response to gamma radiation GO:0010332 28 14 0,000 0,01889531 0,03494398 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01889531 0,03491714 ! cofactor transport GO:0051181 26 14 0,000 0,01889531 0,03489034 ! NADP metabolic process GO:0006739 24 14 0,000 0,01889531 0,03486359 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01889531 0,03483687 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01889531 0,0348102 ! intestinal absorption GO:0050892 25 14 0,000 0,01889531 0,03478356 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01889531 0,03475697 ! oxygen transport GO:0015671 21 14 0,000 0,01889531 0,03473042 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01889531 0,03470391 ! male genitalia development GO:0030539 24 14 0,000 0,01889531 0,03467744 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01889531 0,034651 ! regulation of axon extension GO:0030516 37 14 0,000 0,01889531 0,03462461 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01889531 0,03459826 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01889531 0,03457195 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02023157 0,03698871 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02023157 0,03696063 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02023157 0,03693259 ! superoxide anion generation GO:0042554 20 15 0,000 0,02023157 0,03690459 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02023157 0,03687663 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02023157 0,03684871 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02023157 0,03682084 ! copper ion transport GO:0006825 20 15 0,000 0,02023157 0,03679301 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02023157 0,03676522 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02023157 0,03673747 ! sulfate transport GO:0008272 23 15 0,000 0,02023157 0,03670976 ! response to cAMP GO:0051591 22 15 0,000 0,02023157 0,0366821 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02023157 0,03665448 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02023157 0,0366269 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02023157 0,03659936 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02023157 0,03657186 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02023157 0,03654441 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02023157 0,03651699 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02023157 0,03648962 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02023157 0,03646228 ! pituitary gland development GO:0021983 29 15 0,000 0,02023157 0,03643499 ! vesicle coating GO:0006901 33 15 0,000 0,02023157 0,03640774 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02023157 0,03638053 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02023157 0,03635336 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02023157 0,03632623 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02023157 0,03629914 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02023157 0,03627209 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02023157 0,03624508 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02023157 0,03621812 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02023157 0,03619119 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02023157 0,0361643 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02023157 0,03613745 ! histone deacetylation GO:0016575 20 15 0,000 0,02023157 0,03611064 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02023157 0,03608388 ! tissue regeneration GO:0042246 26 15 0,000 0,02023157 0,03605715 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02023157 0,03603046 ! water homeostasis GO:0030104 27 15 0,000 0,02023157 0,03600381 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02023157 0,0359772 ! muscle maintenance GO:0046716 26 15 0,000 0,02023157 0,03595063 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02023157 0,03592409 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02023157 0,0358976 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02023157 0,03587115 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02023157 0,03584473 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02023157 0,03581836 ! cell killing GO:0001906 29 15 0,000 0,02023157 0,03579202 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02023157 0,03576572 ! detection of bacterium GO:0016045 18 15 0,000 0,02023157 0,03573946 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02023157 0,03571324 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02023157 0,03568706 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02023157 0,03566091 ! peptide hormone processing GO:0016486 23 15 0,000 0,02023157 0,03563481 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02156605 0,0379575 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02156605 0,03792976 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,02156605 0,03790205 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02156605 0,03787438 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02156605 0,03784676 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02156605 0,03781917 ! bone remodeling GO:0046849 27 16 0,000 0,02156605 0,03779163 ! filopodium assembly GO:0046847 32 16 0,000 0,02156605 0,03776412 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02156605 0,03773666 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02156605 0,03770923 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02156605 0,03768185 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02156605 0,0376545 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02156605 0,0376272 ! startle response GO:0001964 28 16 0,000 0,02156605 0,03759993 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02156605 0,03757271 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02156605 0,03754552 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02156605 0,03751837 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02156605 0,03749126 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02156605 0,03746419 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02156605 0,03743716 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02156605 0,03741017 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02156605 0,03738322 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02156605 0,0373563 ! response to osmotic stress GO:0006970 25 16 0,000 0,02156605 0,03732943 ! lysosomal transport GO:0007041 26 16 0,000 0,02156605 0,03730259 ! fructose metabolic process GO:0006000 25 16 0,000 0,02156605 0,03727579 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02156605 0,03724904 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02156605 0,03722231 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02156605 0,03719563 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02156605 0,03716899 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02156605 0,03714238 ! axon cargo transport GO:0008088 43 16 0,000 0,02156605 0,03711581 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02156605 0,03708928 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02156605 0,03706279 ! DNA replication initiation GO:0006270 27 16 0,000 0,02156605 0,03703634 ! neuron recognition GO:0008038 35 16 0,000 0,02156605 0,03700992 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02156605 0,03698354 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02156605 0,0369572 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02156605 0,03693089 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02156605 0,03690463 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02156605 0,0368784 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02156605 0,03685221 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02156605 0,03682605 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02156605 0,03679993 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02156605 0,03677385 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02156605 0,03674781 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02156605 0,0367218 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02156605 0,03669583 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02156605 0,0366699 ! defense response to virus GO:0051607 37 16 0,000 0,02156605 0,036644 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02289875 0,03888101 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02289875 0,03885359 ! metencephalon development GO:0022037 30 17 0,000 0,02289875 0,03882621 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02289875 0,03879887 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02289875 0,03877157 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02289875 0,0387443 ! signal complex assembly GO:0007172 41 17 0,000 0,02289875 0,03871707 ! endothelial cell migration GO:0043542 28 17 0,000 0,02289875 0,03868989 ! inositol metabolic process GO:0006020 28 17 0,000 0,02289875 0,03866273 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02289875 0,03863562 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02289875 0,03860855 ! glial cell development GO:0021782 27 17 0,000 0,02289875 0,03858151 ! limbic system development GO:0021761 36 17 0,000 0,02289875 0,03855451 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02289875 0,03852755 ! adult walking behavior GO:0007628 33 17 0,000 0,02289875 0,03850063 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02289875 0,03847374 ! heart looping GO:0001947 30 17 0,000 0,02289875 0,03844689 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02289875 0,03842008 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02289875 0,03839331 ! myoblast differentiation GO:0045445 45 17 0,000 0,02289875 0,03836657 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02289875 0,03833987 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02289875 0,03831321 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02289875 0,03828659 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02289875 0,03826 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02289875 0,03823345 ! glycine metabolic process GO:0006544 28 17 0,000 0,02289875 0,03820693 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,02289875 0,03818046 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02289875 0,03815401 ! NAD metabolic process GO:0019674 29 17 0,000 0,02289875 0,03812761 ! membrane budding GO:0006900 37 17 0,000 0,02289875 0,03810124 ! DNA integration GO:0015074 29 17 0,000 0,02289875 0,03807491 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02289875 0,03804862 ! regulation of protein binding GO:0043393 33 17 0,000 0,02289875 0,03802236 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02289875 0,03799614 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02289875 0,03796995 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02289875 0,0379438 ! genitalia development GO:0048806 30 17 0,000 0,02289875 0,03791769 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02289875 0,03789161 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02289875 0,03786557 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02289875 0,03783956 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02289875 0,03781359 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02289875 0,03778765 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02289875 0,03776175 ! steroid catabolic process GO:0006706 31 17 0,000 0,02289875 0,03773589 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02289875 0,03771006 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02289875 0,03768427 ! gas transport GO:0015669 25 17 0,000 0,02289875 0,03765851 ! organic cation transport GO:0015695 31 17 0,000 0,02289875 0,03763279 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02289875 0,0376071 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02289875 0,03758144 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02289875 0,03755583 ! microspike assembly GO:0030035 36 17 0,000 0,02289875 0,03753024 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02289875 0,0375047 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,02422969 0,03965757 ! neuron maturation GO:0042551 42 18 0,000 0,02422969 0,03963061 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,02422969 0,03960369 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,02422969 0,0395768 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,02422969 0,03954995 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,02422969 0,03952314 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,02422969 0,03949636 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,02422969 0,03946962 ! memory GO:0007613 31 18 0,000 0,02422969 0,03944291 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02422969 0,03941625 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,02422969 0,03938961 ! patterning of blood vessels GO:0001569 39 18 0,000 0,02422969 0,03936302 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,02422969 0,03933646 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,02422969 0,03930993 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,02422969 0,03928344 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,02422969 0,03925699 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02422969 0,03923057 ! response to retinoic acid GO:0032526 26 18 0,000 0,02422969 0,03920419 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,02422969 0,03917784 ! response to fungus GO:0009620 21 18 0,000 0,02422969 0,03915153 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,02422969 0,03912525 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,02422969 0,03909901 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,02422969 0,03907281 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,02422969 0,03904664 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,02422969 0,0390205 ! vitamin transport GO:0051180 27 18 0,000 0,02422969 0,0389944 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,02422969 0,03896833 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,02422969 0,0389423 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,02422969 0,03891631 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,02422969 0,03889035 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,02422969 0,03886442 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,02422969 0,03883853 ! nerve development GO:0021675 28 18 0,000 0,02422969 0,03881267 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,02422969 0,03878684 ! protein secretion GO:0009306 39 19 0,000 0,02555885 0,04088737 ! positive regulation of translation GO:0045727 30 19 0,000 0,02555885 0,0408602 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02555885 0,04083307 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02555885 0,04080597 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02555885 0,04077891 ! skin development GO:0043588 36 19 0,000 0,02555885 0,04075189 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02555885 0,0407249 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02555885 0,04069795 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02555885 0,04067103 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02555885 0,04064415 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02555885 0,04061731 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02555885 0,0405905 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02555885 0,04056372 ! cerebral cortex development GO:0021987 36 19 0,000 0,02555885 0,04053698 ! pigmentation during development GO:0048066 41 19 0,000 0,02555885 0,04051028 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,02555885 0,04048361 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,02555885 0,04045698 ! heme metabolic process GO:0042168 36 19 0,000 0,02555885 0,04043038 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02555885 0,04040381 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02555885 0,04037728 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02555885 0,04035079 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02555885 0,04032433 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02555885 0,0402979 ! peptide cross-linking GO:0018149 37 19 0,000 0,02555885 0,04027151 ! protein export from nucleus GO:0006611 36 19 0,000 0,02555885 0,04024516 ! heart process GO:0003015 30 19 0,000 0,02555885 0,04021884 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02555885 0,04019255 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02555885 0,0401663 ! visual learning GO:0008542 36 19 0,000 0,02555885 0,04014008 ! cellular pigmentation GO:0033059 36 19 0,000 0,02555885 0,0401139 ! G1 phase GO:0051318 40 19 0,000 0,02555885 0,04008775 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02555885 0,04006163 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02555885 0,04003555 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02555885 0,0400095 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02555885 0,03998349 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02555885 0,03995751 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02555885 0,03993156 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02555885 0,03990565 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02555885 0,03987977 ! cilium assembly GO:0042384 37 19 0,000 0,02555885 0,03985392 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02555885 0,03982811 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02688625 0,04186947 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02688625 0,04184238 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02688625 0,04181534 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02688625 0,04178832 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02688625 0,04176135 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02688625 0,0417344 ! response to vitamin GO:0033273 31 20 0,000 0,02688625 0,0417075 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02688625 0,04168062 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02688625 0,04165378 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02688625 0,04162698 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02688625 0,04160021 ! response to alkaloid GO:0043279 38 20 0,000 0,02688625 0,04157347 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02688625 0,04154677 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02688625 0,04152011 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,02688625 0,04149347 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02688625 0,04146688 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02688625 0,04144031 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02688625 0,04141378 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02688625 0,04138729 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,02688625 0,04136082 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02688625 0,04133439 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02688625 0,041308 ! body fluid secretion GO:0007589 31 20 0,000 0,02688625 0,04128164 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,02688625 0,04125531 ! peptide secretion GO:0002790 35 20 0,000 0,02688625 0,04122902 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02688625 0,04120276 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02688625 0,04117653 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02688625 0,04115034 ! sensory perception of pain GO:0019233 30 20 0,000 0,02688625 0,04112417 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02688625 0,04109805 ! diencephalon development GO:0021536 34 20 0,000 0,02688625 0,04107195 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02688625 0,04104589 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02688625 0,04101986 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02688625 0,04099387 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02688625 0,04096791 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02688625 0,04094198 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02688625 0,04091608 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02688625 0,04089022 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02688625 0,04086439 ! regulation of glucose import GO:0046324 29 20 0,000 0,02688625 0,04083859 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02688625 0,04081282 ! actin filament-based movement GO:0030048 43 20 0,000 0,02688625 0,04078709 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02688625 0,04076139 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02688625 0,04073572 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02688625 0,04071009 ! negative regulation of translation GO:0017148 29 20 0,000 0,02688625 0,04068448 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02688625 0,04065891 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02688625 0,04063337 ! regulation of cell killing GO:0031341 42 21 0,000 0,02821189 0,04261005 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02821189 0,04258332 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02821189 0,04255662 ! hormone secretion GO:0046879 38 21 0,000 0,02821189 0,04252995 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02821189 0,04250332 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02821189 0,04247673 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02821189 0,04245016 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02821189 0,04242363 ! ovarian follicle development GO:0001541 35 21 0,000 0,02821189 0,04239713 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02821189 0,04237067 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02821189 0,04234423 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02821189 0,04231783 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02821189 0,04229147 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02821189 0,04226513 ! cell aging GO:0007569 44 21 0,000 0,02821189 0,04223883 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02821189 0,04221257 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02821189 0,04218633 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02821189 0,04216013 ! cytolysis GO:0019835 24 21 0,000 0,02821189 0,04213396 ! vasodilation GO:0042311 39 21 0,000 0,02821189 0,04210782 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02821189 0,04208172 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02821189 0,04205564 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02821189 0,0420296 ! oogenesis GO:0048477 36 21 0,000 0,02821189 0,04200359 ! DNA modification GO:0006304 34 21 0,000 0,02821189 0,04197762 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02821189 0,04195167 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02821189 0,04192576 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02821189 0,04189988 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02821189 0,04187403 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02821189 0,04184822 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02821189 0,04182243 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02821189 0,04179668 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02821189 0,04177096 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02821189 0,04174527 ! collagen catabolic process GO:0030574 28 21 0,000 0,02821189 0,04171961 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02821189 0,04169398 ! gut development GO:0048565 39 21 0,000 0,02821189 0,04166839 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,02953576 0,04359696 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02953576 0,04357023 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02953576 0,04354353 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02953576 0,04351687 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02953576 0,04349024 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02953576 0,04346364 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02953576 0,04343707 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02953576 0,04341054 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02953576 0,04338403 ! regeneration GO:0031099 41 22 0,000 0,02953576 0,04335756 ! keratinization GO:0031424 28 22 0,000 0,02953576 0,04333113 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,02953576 0,04330472 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02953576 0,04327835 ! sensory perception of taste GO:0050909 28 22 0,000 0,02953576 0,04325201 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02953576 0,0432257 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02953576 0,04319942 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02953576 0,04317318 ! vacuolar transport GO:0007034 36 22 0,000 0,02953576 0,04314696 ! lysosome organization GO:0007040 41 22 0,000 0,02953576 0,04312078 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02953576 0,04309463 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02953576 0,04306851 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02953576 0,04304243 ! fucose metabolic process GO:0006004 39 22 0,000 0,02953576 0,04301637 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02953576 0,04299035 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02953576 0,04296436 ! ureteric bud development GO:0001657 43 22 0,000 0,02953576 0,0429384 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02953576 0,04291247 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02953576 0,04288657 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02953576 0,0428607 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02953576 0,04283487 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02953576 0,04280906 ! sarcomere organization GO:0045214 30 22 0,000 0,02953576 0,04278329 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,02953576 0,04275755 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02953576 0,04273184 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02953576 0,04270616 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02953576 0,04268051 ! protein stabilization GO:0050821 39 22 0,000 0,02953576 0,04265489 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03085788 0,04453753 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03085788 0,04451082 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,03085788 0,04448416 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03085788 0,04445752 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03085788 0,04443091 ! gluconeogenesis GO:0006094 33 23 0,000 0,03085788 0,04440434 ! viral genome replication GO:0019079 41 23 0,000 0,03085788 0,0443778 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03085788 0,04435129 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03085788 0,04432481 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03085788 0,04429836 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03085788 0,04427195 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03085788 0,04424556 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03085788 0,04421921 ! visual behavior GO:0007632 42 23 0,000 0,03085788 0,04419289 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,03085788 0,0441666 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03085788 0,04414034 ! response to ethanol GO:0045471 46 23 0,000 0,03085788 0,04411411 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03085788 0,04408792 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03085788 0,04406175 ! peroxisome organization GO:0007031 37 23 0,000 0,03085788 0,04403562 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03085788 0,04400952 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03085788 0,04398344 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03085788 0,0439574 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03085788 0,04393139 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03085788 0,04390541 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03085788 0,04387947 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03085788 0,04385355 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03085788 0,04382766 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03085788 0,0438018 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03085788 0,04377598 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03085788 0,04375018 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03085788 0,04372441 ! fatty acid transport GO:0015908 44 23 0,000 0,03085788 0,04369868 ! platelet activation GO:0030168 37 23 0,000 0,03085788 0,04367297 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03085788 0,0436473 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03085788 0,04362165 ! hormone transport GO:0009914 40 23 0,000 0,03085788 0,04359604 ! cell-cell recognition GO:0009988 25 23 0,000 0,03085788 0,04357045 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03085788 0,0435449 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03085788 0,04351938 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03085788 0,04349388 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03085788 0,04346842 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03085788 0,04344298 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03217824 0,04527534 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,03217824 0,04524888 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03217824 0,04522245 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03217824 0,04519605 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03217824 0,04516968 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03217824 0,04514334 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03217824 0,04511704 ! vesicle docking GO:0048278 47 24 0,000 0,03217824 0,04509076 ! spinal cord development GO:0021510 47 24 0,000 0,03217824 0,04506451 ! vacuole organization GO:0007033 43 24 0,000 0,03217824 0,0450383 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03217824 0,04501211 ! digestive system process GO:0022600 39 24 0,000 0,03217824 0,04498596 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03217824 0,04495983 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03217824 0,04493374 ! regulation of behavior GO:0050795 43 24 0,000 0,03217824 0,04490768 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03217824 0,04488164 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03217824 0,04485564 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03217824 0,04482967 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,03217824 0,04480372 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03217824 0,04477781 ! membrane depolarization GO:0051899 39 24 0,000 0,03217824 0,04475193 ! pallium development GO:0021543 49 24 0,000 0,03217824 0,04472607 ! pentose metabolic process GO:0019321 35 24 0,000 0,03217824 0,04470025 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03217824 0,04467446 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03217824 0,04464869 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03217824 0,04462296 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03217824 0,04459725 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03217824 0,04457158 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03217824 0,04454593 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03217824 0,04452032 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03217824 0,04449473 ! regulation of amine transport GO:0051952 40 24 0,000 0,03217824 0,04446918 ! protein tetramerization GO:0051262 52 24 0,000 0,03217824 0,04444365 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03349684 0,04623832 ! myelination GO:0042552 45 25 0,000 0,03349684 0,04621181 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03349684 0,04618532 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03349684 0,04615887 ! phototransduction GO:0007602 33 25 0,000 0,03349684 0,04613245 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03349684 0,04610606 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,03349684 0,0460797 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03349684 0,04605337 ! sperm motility GO:0030317 31 25 0,000 0,03349684 0,04602706 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,03349684 0,04600079 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03349684 0,04597455 ! receptor metabolic process GO:0043112 46 25 0,000 0,03349684 0,04594834 ! chromosome condensation GO:0030261 45 25 0,000 0,03349684 0,04592216 ! response to starvation GO:0042594 42 25 0,000 0,03349684 0,04589601 ! neural crest cell development GO:0014032 54 25 0,000 0,03349684 0,04586989 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03349684 0,04584379 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03349684 0,04581773 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03349684 0,0457917 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03349684 0,0457657 ! interaction with host GO:0051701 62 25 0,000 0,03349684 0,04573972 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03349684 0,04571378 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,03349684 0,04568786 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03349684 0,04566198 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,03349684 0,04563612 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03349684 0,04561029 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03349684 0,0455845 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,03349684 0,04555873 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03349684 0,04553299 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03349684 0,04550728 ! telomere organization GO:0032200 43 25 0,000 0,03349684 0,0454816 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03349684 0,04545595 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03349684 0,04543032 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03481369 0,04718971 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03481369 0,04716314 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03481369 0,0471366 ! initiation of viral infection GO:0019059 57 26 0,000 0,03481369 0,04711008 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03481369 0,0470836 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03481369 0,04705715 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03481369 0,04703073 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03481369 0,04700434 ! molting cycle process GO:0022404 50 26 0,000 0,03481369 0,04697798 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03481369 0,04695164 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03481369 0,04692534 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03481369 0,04689907 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03481369 0,04687282 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03481369 0,04684661 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,03481369 0,04682042 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03481369 0,04679426 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,03481369 0,04676814 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,03481369 0,04674204 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03481369 0,04671597 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03481369 0,04668993 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03481369 0,04666392 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03481369 0,04663793 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03481369 0,04661198 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03481369 0,04658606 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03481369 0,04656016 ! blastocyst development GO:0001824 49 26 0,000 0,03481369 0,04653429 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03481369 0,04650846 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03481369 0,04648265 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03481369 0,04645687 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,03612879 0,04818507 ! neuron fate commitment GO:0048663 48 27 0,000 0,03612879 0,04815837 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,03612879 0,0481317 ! iron ion transport GO:0006826 59 27 0,000 0,03612879 0,04810507 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,03612879 0,04807846 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,03612879 0,04805188 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,03612879 0,04802534 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,03612879 0,04799882 ! fat cell differentiation GO:0045444 50 27 0,000 0,03612879 0,04797233 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,03612879 0,04794587 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,03612879 0,04791944 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,03612879 0,04789303 ! autophagy GO:0006914 41 27 0,000 0,03612879 0,04786666 ! male gonad development GO:0008584 44 27 0,000 0,03612879 0,04784032 ! response to toxin GO:0009636 47 27 0,000 0,03612879 0,047814 ! primary neural tube formation GO:0014020 51 27 0,000 0,03612879 0,04778772 ! base-excision repair GO:0006284 41 27 0,000 0,03612879 0,04776146 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,03612879 0,04773523 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,03612879 0,04770903 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,03612879 0,04768286 ! glutathione metabolic process GO:0006749 39 27 0,000 0,03612879 0,04765672 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,03612879 0,04763061 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,03612879 0,04760452 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,03612879 0,04757847 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,03612879 0,04755244 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03744214 0,04925412 ! circadian rhythm GO:0007623 50 28 0,000 0,03744214 0,0492272 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03744214 0,04920032 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,03744214 0,04917346 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03744214 0,04914663 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03744214 0,04911984 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03744214 0,04909307 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03744214 0,04906633 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03744214 0,04903962 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03744214 0,04901294 ! synaptogenesis GO:0007416 42 28 0,000 0,03744214 0,04898629 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03744214 0,04895966 ! lipid oxidation GO:0034440 43 28 0,000 0,03744214 0,04893307 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03744214 0,0489065 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03744214 0,04887997 ! translational initiation GO:0006413 65 29 0,000 0,03875374 0,0505648 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,03875374 0,0505374 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03875374 0,05051002 ! regulation of pH GO:0006885 43 29 0,000 0,03875374 0,05048267 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03875374 0,05045536 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03875374 0,05042807 ! catechol metabolic process GO:0009712 54 29 0,000 0,03875374 0,05040081 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03875374 0,05037358 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03875374 0,05034638 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03875374 0,05031921 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03875374 0,05029207 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03875374 0,05026496 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03875374 0,05023788 ! cell fate determination GO:0001709 60 29 0,000 0,03875374 0,05021082 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03875374 0,0501838 ! detection of light stimulus GO:0009583 38 29 0,000 0,03875374 0,0501568 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,03875374 0,05012984 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,03875374 0,0501029 ! tissue homeostasis GO:0001894 48 29 0,000 0,03875374 0,05007599 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03875374 0,05004911 ! phenol metabolic process GO:0018958 55 30 0,000 0,0400636 0,051713 ! zinc ion transport GO:0006829 45 30 0,000 0,0400636 0,05168527 ! membrane docking GO:0022406 61 30 0,000 0,0400636 0,05165757 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0400636 0,0516299 ! cell junction assembly GO:0034329 78 30 0,000 0,0400636 0,05160226 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0400636 0,05157465 ! acute-phase response GO:0006953 49 30 0,000 0,0400636 0,05154707 ! myofibril assembly GO:0030239 47 30 0,000 0,0400636 0,05151952 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,0400636 0,051492 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0400636 0,05146451 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0400636 0,05143705 ! phospholipid transport GO:0015914 51 30 0,000 0,0400636 0,05140961 ! ensheathment of neurons GO:0007272 57 30 0,000 0,0400636 0,05138221 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0400636 0,05135484 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0400636 0,05132749 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,0400636 0,05130017 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0400636 0,05127289 ! eye morphogenesis GO:0048592 60 30 0,000 0,0400636 0,05124563 ! regulation of B cell activation GO:0050864 50 30 0,000 0,0400636 0,0512184 ! response to heat GO:0009408 50 30 0,000 0,0400636 0,0511912 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04137172 0,05283459 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04137172 0,05280656 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04137172 0,05277856 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04137172 0,05275059 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04137172 0,05272265 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04137172 0,05269474 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,04137172 0,05266686 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04137172 0,05263901 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04137172 0,05261118 ! ovulation cycle process GO:0022602 49 31 0,000 0,04137172 0,05258339 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04137172 0,05255563 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,04137172 0,0525279 ! peptide transport GO:0015833 55 31 0,000 0,04137172 0,05250019 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,04137172 0,05247252 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04137172 0,05244487 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,04137172 0,05241725 ! natural killer cell activation GO:0030101 45 31 0,000 0,04137172 0,05238966 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04137172 0,0523621 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04137172 0,05233457 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04137172 0,05230707 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04137172 0,0522796 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04137172 0,05225216 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,0426781 0,05387383 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,0426781 0,05384558 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,0426781 0,05381735 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,0426781 0,05378916 ! cholesterol transport GO:0030301 56 32 0,000 0,0426781 0,053761 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,0426781 0,05373287 ! spliceosome assembly GO:0000245 67 32 0,000 0,0426781 0,05370477 ! spindle organization GO:0007051 46 32 0,000 0,0426781 0,05367669 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,0426781 0,05364865 ! metanephros development GO:0001656 74 32 0,000 0,0426781 0,05362063 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,0426781 0,05359265 ! response to ionizing radiation GO:0010212 65 32 0,000 0,0426781 0,05356469 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,0426781 0,05353676 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,0426781 0,05350887 ! muscle cell development GO:0055001 49 32 0,000 0,0426781 0,053481 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,0426781 0,05345316 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,0426781 0,05342534 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,0426781 0,05339756 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,0426781 0,05336981 ! ovulation cycle GO:0042698 51 32 0,000 0,0426781 0,05334208 ! peripheral nervous system development GO:0007422 64 32 0,000 0,0426781 0,05331439 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,0426781 0,05328672 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,0426781 0,05325908 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,0426781 0,05323147 ! gene silencing GO:0016458 65 32 0,000 0,0426781 0,05320389 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,04398275 0,05480191 ! post-embryonic development GO:0009791 69 33 0,000 0,04398275 0,05477354 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,04398275 0,05474521 ! protein targeting to membrane GO:0006612 68 33 0,000 0,04398275 0,0547169 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,04398275 0,05468862 ! ceramide metabolic process GO:0006672 64 33 0,000 0,04398275 0,05466037 ! cell fate specification GO:0001708 52 33 0,000 0,04398275 0,05463216 ! sterol transport GO:0015918 57 33 0,000 0,04398275 0,05460397 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,04398275 0,0545758 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,04398275 0,05454767 ! adult locomotory behavior GO:0008344 59 33 0,000 0,04398275 0,05451957 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,04398275 0,0544915 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,04398275 0,05446345 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,04528565 0,05604799 ! glial cell differentiation GO:0010001 63 34 0,000 0,04528565 0,05601917 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,04528565 0,05599038 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,04528565 0,05596162 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,04528565 0,0559329 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,04528565 0,0559042 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,04528565 0,05587553 ! mismatch repair GO:0006298 46 34 0,000 0,04528565 0,05584689 ! spermatid development GO:0007286 63 34 0,000 0,04528565 0,05581828 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,04528565 0,0557897 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,04528565 0,05576115 ! placenta development GO:0001890 53 34 0,000 0,04528565 0,05573263 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,04528565 0,05570413 ! regulation of muscle development GO:0048634 70 35 0,000 0,04658683 0,05727538 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,04658683 0,05724613 ! negative regulation of secretion GO:0051048 63 35 0,000 0,04658683 0,0572169 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,04658683 0,05718771 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,04658683 0,05715855 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,04658683 0,05712942 ! odontogenesis GO:0042476 66 35 0,000 0,04658683 0,05710031 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,04658683 0,05707124 ! female gonad development GO:0008585 58 35 0,000 0,04658683 0,0570422 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,04658683 0,05701318 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,04658683 0,0569842 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,04658683 0,05695524 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,04658683 0,05692631 ! neural tube formation GO:0001841 67 35 0,000 0,04658683 0,05689742 ! vesicle localization GO:0051648 64 35 0,000 0,04658683 0,05686855 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,04788628 0,05842514 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,04788628 0,05839553 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,04788628 0,05836595 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,04788628 0,0583364 ! cell junction organization GO:0034330 86 36 0,000 0,04788628 0,05830687 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,04788628 0,05827738 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,04788628 0,05824792 ! positive regulation of cell development GO:0010720 80 36 0,000 0,04788628 0,05821848 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,04788628 0,05818908 ! regulation of proteolysis GO:0030162 72 36 0,000 0,04788628 0,05815971 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,04788628 0,05813036 ! aerobic respiration GO:0009060 55 36 0,000 0,04788628 0,05810105 ! embryonic organ development GO:0048568 57 36 0,000 0,04788628 0,05807176 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,04788628 0,05804251 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,04788628 0,05801328 ! RNA export from nucleus GO:0006405 56 37 0,000 0,04918399 0,05955546 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,04918399 0,0595255 ! meiosis I GO:0007127 65 37 0,000 0,04918399 0,05949557 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,04918399 0,05946567 ! sister chromatid segregation GO:0000819 58 37 0,000 0,04918399 0,05943581 ! actomyosin structure organization GO:0031032 62 37 0,000 0,04918399 0,05940597 ! organic anion transport GO:0015711 68 37 0,000 0,04918399 0,05937616 ! tissue remodeling GO:0048771 76 37 0,000 0,04918399 0,05934638 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,04918399 0,05931664 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,04918399 0,05928692 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,04918399 0,05925723 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,04918399 0,05922757 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,04918399 0,05919794 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,04918399 0,05916835 ! pigment metabolic process GO:0042440 80 37 0,000 0,04918399 0,05913878 ! spermatid differentiation GO:0048515 66 37 0,000 0,04918399 0,05910924 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,04918399 0,05907973 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,05047999 0,06060621 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,05047999 0,06057598 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,05047999 0,06054579 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,05047999 0,06051562 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,05047999 0,06048548 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,05047999 0,06045538 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,05047999 0,0604253 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,05047999 0,06039525 ! lipid homeostasis GO:0055088 67 38 0,000 0,05047999 0,06036523 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,05047999 0,06033525 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,05047999 0,06030529 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,05047999 0,06027536 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,05047999 0,06024546 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,05047999 0,06021559 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,05047999 0,06018575 ! mRNA catabolic process GO:0006402 71 39 0,000 0,05177426 0,0616983 ! mammary gland development GO:0030879 86 39 0,000 0,05177426 0,06166775 ! learning GO:0007612 77 39 0,000 0,05177426 0,06163724 ! ear morphogenesis GO:0042471 60 39 0,000 0,05177426 0,06160676 ! organic ether metabolic process GO:0018904 55 39 0,000 0,05177426 0,0615763 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05177426 0,06154588 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05177426 0,06151549 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05177426 0,06148512 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05177426 0,06145479 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05177426 0,06142449 ! RNA modification GO:0009451 57 39 0,000 0,05177426 0,06139421 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05177426 0,06136397 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,0530668 0,06286496 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,0530668 0,06283402 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,0530668 0,06280311 ! feeding behavior GO:0007631 59 40 0,000 0,0530668 0,06277224 ! negative regulation of binding GO:0051100 72 40 0,000 0,0530668 0,06274139 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,0530668 0,06271058 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,0530668 0,06267979 ! maintenance of protein location GO:0045185 91 40 0,000 0,0530668 0,06264903 ! cytokinesis GO:0000910 72 40 0,000 0,0530668 0,06261831 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,05435763 0,06411003 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,05435763 0,06407862 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,05435763 0,06404724 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,05435763 0,06401589 ! gliogenesis GO:0042063 88 41 0,000 0,05435763 0,06398457 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,05435763 0,06395328 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,05435763 0,06392203 ! T cell differentiation GO:0030217 81 41 0,000 0,05435763 0,0638908 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,05435763 0,0638596 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,05435763 0,06382844 ! female gamete generation GO:0007292 61 41 0,000 0,05435763 0,0637973 ! polyol metabolic process GO:0019751 66 41 0,000 0,05435763 0,06376619 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,05564675 0,06524662 ! regulation of tube size GO:0035150 71 42 0,000 0,05564675 0,06521484 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,05564675 0,06518309 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,05564675 0,06515137 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,05564675 0,06511968 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,05564675 0,06508803 ! neuron migration GO:0001764 79 42 0,000 0,05564675 0,0650564 ! regulation of protein secretion GO:0050708 71 42 0,000 0,05564675 0,0650248 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,05564675 0,06499324 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,05693414 0,0664646 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,05693414 0,06643237 ! glucose transport GO:0015758 65 43 0,000 0,05693414 0,06640017 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,05693414 0,066368 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,05693414 0,06633586 ! neural tube development GO:0021915 77 43 0,000 0,05693414 0,06630375 ! striated muscle contraction GO:0006941 77 43 0,000 0,05693414 0,06627167 ! phagocytosis GO:0006909 90 43 0,000 0,05693414 0,06623963 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,05693414 0,06620761 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,05821983 0,06767 ! hexose transport GO:0008645 67 44 0,000 0,05821983 0,06763733 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,05821983 0,06760468 ! male sex differentiation GO:0046661 76 44 0,000 0,05821983 0,06757207 ! double-strand break repair GO:0006302 81 44 0,000 0,05821983 0,06753949 ! biopolymer methylation GO:0043414 84 44 0,000 0,05821983 0,06750694 ! B cell differentiation GO:0030183 107 44 0,000 0,05821983 0,06747443 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,05821983 0,06744194 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,05821983 0,06740948 ! developmental growth GO:0048589 82 44 0,000 0,05821983 0,06737706 ! maintenance of location in cell GO:0051651 97 44 0,000 0,05821983 0,06734467 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,0595038 0,0687968 ! glycolysis GO:0006096 65 45 0,000 0,0595038 0,06876376 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,0595038 0,06873075 ! leukocyte migration GO:0050900 68 45 0,000 0,0595038 0,06869777 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,0595038 0,06866482 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,0595038 0,0686319 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,0595038 0,06859902 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,0595038 0,06856616 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,0595038 0,06853334 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,0595038 0,06850055 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,0595038 0,06846779 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,0595038 0,06843506 ! cell growth GO:0016049 84 45 0,000 0,0595038 0,06840237 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,06078607 0,06984302 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,06078607 0,06980968 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,06078607 0,06977638 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,06078607 0,0697431 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,06078607 0,06970986 ! pigmentation GO:0043473 100 46 0,000 0,06078607 0,06967665 ! response to insulin stimulus GO:0032868 95 46 0,000 0,06078607 0,06964347 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06206663 0,07107678 ! response to calcium ion GO:0051592 81 47 0,000 0,06206663 0,07104297 ! endosome transport GO:0016197 108 47 0,000 0,06206663 0,07100919 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06206663 0,07097544 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06206663 0,07094172 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06206663 0,07090803 ! JNK cascade GO:0007254 91 47 0,000 0,06206663 0,07087438 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,06206663 0,07084076 ! methylation GO:0032259 90 47 0,000 0,06206663 0,07080717 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,06334549 0,07223187 ! Notch signaling pathway GO:0007219 96 48 0,000 0,06334549 0,07219766 ! cellular component disassembly GO:0022411 86 48 0,000 0,06334549 0,07216347 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,06334549 0,07212932 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,06334549 0,0720952 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,06334549 0,07206111 ! activation of caspase activity GO:0006919 84 48 0,000 0,06334549 0,07202706 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,06334549 0,07199303 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,06334549 0,07195904 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,06334549 0,07192508 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,06334549 0,07189116 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,06462265 0,07330603 ! regulation of action potential GO:0001508 95 49 0,000 0,06462265 0,07327148 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,06462265 0,07323697 ! regulation of ion transport GO:0043269 77 49 0,000 0,06462265 0,07320249 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,06462265 0,07316804 ! peptide metabolic process GO:0006518 76 49 0,000 0,06462265 0,07313363 ! response to temperature stimulus GO:0009266 76 49 0,000 0,06462265 0,07309924 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,06462265 0,07306489 ! endocrine system development GO:0035270 104 49 0,000 0,06462265 0,07303057 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,06462265 0,07299629 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,06462265 0,07296203 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,06462265 0,07292781 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,06462265 0,07289362 ! neuromuscular process GO:0050905 99 50 0,000 0,06589811 0,07429749 ! inner ear development GO:0048839 79 50 0,000 0,06589811 0,07426269 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,06589811 0,07422792 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,06589811 0,07419319 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,06589811 0,07415849 ! viral infectious cycle GO:0019058 99 51 0,000 0,06717187 0,07555657 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,06717187 0,07552127 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,06717187 0,07548599 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,06717187 0,07545075 ! excretion GO:0007588 83 51 0,000 0,06717187 0,07541554 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,06717187 0,07538037 ! chromatin remodeling GO:0006338 109 51 0,000 0,06717187 0,07534523 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,06717187 0,07531012 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,06717187 0,07527504 ! vesicle organization GO:0016050 107 51 0,000 0,06717187 0,07524 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,06717187 0,07520498 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,06717187 0,07517001 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,06717187 0,07513506 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,06844393 0,07652235 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,06844393 0,07648681 ! membrane fusion GO:0006944 110 52 0,000 0,06844393 0,0764513 ! positive regulation of growth GO:0045927 90 52 0,000 0,06844393 0,07641583 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,06844393 0,07638038 ! amino acid activation GO:0043038 92 52 0,000 0,06844393 0,07634497 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,06844393 0,07630959 ! synapse organization GO:0050808 85 52 0,000 0,06844393 0,07627425 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,06971431 0,07765399 ! RNA catabolic process GO:0006401 93 53 0,000 0,06971431 0,07761806 ! regulation of translational initiation GO:0006446 82 53 0,000 0,06971431 0,07758216 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,06971431 0,07754629 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,06971431 0,07751045 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,06971431 0,07747465 ! cell maturation GO:0048469 100 53 0,000 0,06971431 0,07743888 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,06971431 0,07740315 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,06971431 0,07736745 ! response to UV GO:0009411 104 53 0,000 0,06971431 0,07733178 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,07098299 0,0787028 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,07098299 0,07866655 ! cell recognition GO:0008037 85 54 0,000 0,07098299 0,07863033 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,07098299 0,07859415 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,07098299 0,07855799 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,07098299 0,07852187 ! chloride transport GO:0006821 90 55 0,000 0,07224999 0,0798867 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,07224999 0,07985001 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,07224999 0,07981335 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,07224999 0,07977672 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,07224999 0,07974012 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,07224999 0,07970356 ! aging GO:0007568 103 55 0,000 0,07224999 0,07966703 ! heart morphogenesis GO:0003007 97 55 0,000 0,07224999 0,07963054 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,07224999 0,07959408 ! RNA elongation GO:0006354 79 55 0,000 0,07224999 0,07955765 ! nuclear export GO:0051168 97 55 0,000 0,07224999 0,07952126 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,07224999 0,0794849 ! regulation of actin filament length GO:0030832 105 56 0,000 0,0735153 0,08083995 ! sensory perception of smell GO:0007608 80 56 0,000 0,0735153 0,08080302 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0735153 0,08076612 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0735153 0,08072926 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0735153 0,08069243 ! regulation of DNA replication GO:0006275 101 56 0,000 0,0735153 0,08065563 ! proton transport GO:0015992 94 56 0,000 0,0735153 0,08061887 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,0735153 0,08058214 ! muscle fiber development GO:0048747 112 57 0,000 0,07477892 0,08192991 ! lipid modification GO:0030258 97 57 0,000 0,07477892 0,08189262 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,07477892 0,08185536 ! maintenance of location GO:0051235 118 57 0,000 0,07477892 0,08181814 ! hydrogen transport GO:0006818 97 58 0,000 0,07604087 0,08316106 ! regulation of endocytosis GO:0030100 91 58 0,000 0,07604087 0,08312328 ! adult behavior GO:0030534 99 58 0,000 0,07604087 0,08308553 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,07604087 0,08304781 ! positive regulation of secretion GO:0051047 95 59 0,000 0,07730113 0,0843859 ! regulation of cellular component size GO:0032535 109 59 0,000 0,07730113 0,08434763 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,07730113 0,0843094 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,07730113 0,0842712 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,07730113 0,08423303 ! DNA catabolic process GO:0006308 86 59 0,000 0,07730113 0,0841949 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,07730113 0,0841568 ! establishment of organelle localization GO:0051656 109 59 0,000 0,07730113 0,08411874 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,07855972 0,08544968 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,07855972 0,08541107 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,07855972 0,08537249 ! regulation of heart contraction GO:0008016 110 60 0,000 0,07855972 0,08533395 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,07855972 0,08529544 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,07855972 0,08525697 ! kidney development GO:0001822 122 60 0,000 0,07855972 0,08521853 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,07981664 0,08654296 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,07981664 0,08650398 ! tRNA processing GO:0008033 89 61 0,000 0,07981664 0,08646503 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,07981664 0,08642611 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,07981664 0,08638724 ! ear development GO:0043583 103 62 0,000 0,08107188 0,08770636 ! viral reproductive process GO:0022415 126 62 0,000 0,08107188 0,08766694 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,08107188 0,08762755 ! gonad development GO:0008406 98 62 0,000 0,08107188 0,08758821 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,08107188 0,08754889 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,08232545 0,08886273 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,08232545 0,08882288 ! detection of external stimulus GO:0009581 91 63 0,000 0,08232545 0,08878307 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,08232545 0,08874329 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,08357735 0,09005244 ! cell redox homeostasis GO:0045454 102 64 0,000 0,08357735 0,09001213 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,08357735 0,08997186 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,08357735 0,08993162 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,08357735 0,08989142 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,08482758 0,09119534 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,08482758 0,09115461 ! germ cell development GO:0007281 118 65 0,000 0,08482758 0,09111391 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,08482758 0,09107326 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,08607616 0,09237254 ! actin filament organization GO:0007015 148 66 0,000 0,08607616 0,09233136 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,08607616 0,09229021 ! extracellular matrix organization GO:0030198 133 66 0,000 0,08607616 0,0922491 ! secondary metabolic process GO:0019748 116 66 0,000 0,08607616 0,09220803 ! developmental maturation GO:0021700 116 66 0,000 0,08607616 0,09216699 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,08732307 0,09346054 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,08732307 0,09341898 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,08732307 0,09337747 ! activation of MAPK activity GO:0000187 115 67 0,000 0,08732307 0,09333598 ! chromosome segregation GO:0007059 113 67 0,000 0,08732307 0,09329454 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,08732307 0,09325313 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,08732307 0,09321176 ! hexose catabolic process GO:0019320 104 67 0,000 0,08732307 0,09317042 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,08732307 0,09312912 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,08732307 0,09308786 ! adaptive immune response GO:0002250 119 67 0,000 0,08732307 0,09304663 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,08732307 0,09300544 ! amino acid transport GO:0006865 125 68 0,000 0,08856832 0,09428999 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,08856832 0,09424828 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,08856832 0,09420662 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,08856832 0,09416499 ! regulation of lipase activity GO:0060191 130 68 0,000 0,08856832 0,0941234 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,08856832 0,09408184 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,08856832 0,09404032 ! negative regulation of cell size GO:0045792 134 69 0,000 0,08981191 0,09531868 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,08981191 0,09527665 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,08981191 0,09523466 ! urogenital system development GO:0001655 137 69 0,000 0,08981191 0,09519271 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,08981191 0,09515079 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,08981191 0,09510891 ! antigen processing and presentation GO:0019882 104 69 0,000 0,08981191 0,09506707 ! amine catabolic process GO:0009310 117 71 0,000 0,09229413 0,09765157 ! reproductive structure development GO:0048608 113 71 0,000 0,09229413 0,09760865 ! humoral immune response GO:0006959 109 71 0,000 0,09229413 0,09756576 ! B cell activation GO:0042113 160 71 0,000 0,09229413 0,09752291 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,09229413 0,0974801 ! regulation of immune effector process GO:0002697 137 71 0,000 0,09229413 0,09743733 ! acute inflammatory response GO:0002526 113 72 0,000 0,09353276 0,09870168 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,09353276 0,0986584 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,09353276 0,09861517 ! carbohydrate transport GO:0008643 110 72 0,000 0,09353276 0,09857198 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,09353276 0,09852882 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,09353276 0,0984857 ! learning or memory GO:0007611 147 73 0,000 0,09476974 0,09974453 ! regulation of blood pressure GO:0008217 125 73 0,000 0,09476974 0,09970092 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,09476974 0,09965734 ! axon guidance GO:0007411 139 73 0,000 0,09476974 0,09961381 ! fertilization GO:0009566 90 73 0,000 0,09476974 0,09957031 ! transition metal ion transport GO:0000041 126 74 0,000 0,09600508 0,10082419 ! neurotransmitter transport GO:0006836 123 74 0,000 0,09600508 0,1007802 ! meiosis GO:0007126 121 74 0,000 0,09600508 0,10073625 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,09600508 0,10069234 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,09600508 0,10064846 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,09600508 0,10060463 ! organelle localization GO:0051640 136 74 0,000 0,09600508 0,10056083 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,09723877 0,10180874 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,09723877 0,10176445 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,09723877 0,10172021 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,09723877 0,101676 ! meiotic cell cycle GO:0051321 122 75 0,000 0,09723877 0,10163183 ! rhythmic process GO:0048511 128 75 0,000 0,09723877 0,1015877 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,09723877 0,10154361 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,09847082 0,10278559 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,09847082 0,10274102 ! defense response to bacterium GO:0042742 89 76 0,000 0,09847082 0,10269649 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,09847082 0,10265199 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,09847082 0,10260753 ! regulation of catabolic process GO:0009894 161 76 0,000 0,09847082 0,10256311 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,09970123 0,10379972 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,09970123 0,10375482 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,09970123 0,10370997 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,09970123 0,10366515 ! blood coagulation GO:0007596 146 78 0,000 0,10093 0,10489744 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,10093 0,10485215 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,10093 0,10480689 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,10215713 0,1060354 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,10215713 0,10598968 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,10215713 0,10594399 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,10215713 0,10589834 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,10215713 0,10585274 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,10338263 0,10707646 ! response to metal ion GO:0010038 140 80 0,000 0,10338263 0,10703038 ! muscle cell differentiation GO:0042692 159 80 0,000 0,10338263 0,10698435 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,10338263 0,10693835 ! protein import into nucleus GO:0006606 158 80 0,000 0,10338263 0,1068924 ! inorganic anion transport GO:0015698 138 80 0,000 0,10338263 0,10684648 ! T cell activation GO:0042110 168 81 0,000 0,1046065 0,10806494 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,1046065 0,10801856 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,1046065 0,10797222 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,1046065 0,10792592 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,1046065 0,10787966 ! nuclear import GO:0051170 161 81 0,000 0,1046065 0,10783343 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,1046065 0,10778725 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,10582874 0,10899997 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,10582874 0,10895333 ! response to drug GO:0042493 143 82 0,000 0,10582874 0,10890673 ! response to nutrient GO:0007584 125 82 0,000 0,10582874 0,10886017 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,10582874 0,10881365 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,10582874 0,10876717 ! regulation of lyase activity GO:0051339 160 83 0,000 0,10704935 0,10997469 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,10826833 0,11117952 ! hemostasis GO:0007599 158 84 0,000 0,10826833 0,11113208 ! negative regulation of transport GO:0051051 153 84 0,000 0,10826833 0,11108469 ! negative regulation of growth GO:0045926 155 84 0,000 0,10826833 0,11103734 ! regulation of ligase activity GO:0051340 142 84 0,000 0,10826833 0,11099003 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,10826833 0,11094276 ! response to unfolded protein GO:0006986 131 85 0,000 0,10948569 0,11214243 ! nucleosome assembly GO:0006334 122 85 0,000 0,10948569 0,11209471 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,10948569 0,11204703 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,10948569 0,11199939 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,11070143 0,11319492 ! response to inorganic substance GO:0010035 153 86 0,000 0,11070143 0,11314683 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,11070143 0,11309879 ! chromatin assembly GO:0031497 124 86 0,000 0,11070143 0,11305078 ! tube morphogenesis GO:0035239 176 86 0,000 0,11070143 0,11300282 ! mitochondrion organization GO:0007005 148 86 0,000 0,11070143 0,1129549 ! alcohol catabolic process GO:0046164 130 86 0,000 0,11070143 0,11290701 ! amine transport GO:0015837 155 86 0,000 0,11070143 0,11285917 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,11191555 0,11404863 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,11191555 0,11400035 ! protein localization in nucleus GO:0034504 176 87 0,000 0,11191555 0,1139521 ! cellular respiration GO:0045333 135 88 0,000 0,11312805 0,11513794 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,11312805 0,11508926 ! gland development GO:0048732 206 88 0,000 0,11312805 0,11504062 ! regulation of neurological system process GO:0031644 148 88 0,000 0,11312805 0,11499201 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,11312805 0,11494345 ! cellular defense response GO:0006968 114 89 0,000 0,11433894 0,11612473 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,11433894 0,11607574 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,11433894 0,11602678 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,11554822 0,11720447 ! sex differentiation GO:0007548 145 90 0,000 0,11554822 0,11715508 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,11554822 0,11710573 ! sterol metabolic process GO:0016125 152 91 0,000 0,11675588 0,11827985 ! response to protein stimulus GO:0051789 149 91 0,000 0,11675588 0,11823007 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,11675588 0,11818033 ! regulation of defense response GO:0031347 149 92 0,000 0,11796194 0,11935089 ! nucleosome organization GO:0034728 138 92 0,000 0,11796194 0,11930072 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,11796194 0,1192506 ! vitamin metabolic process GO:0006766 139 92 0,000 0,11796194 0,11920051 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,11916638 0,12036705 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 0,000 0,11916638 0,12031654 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,11916638 0,12026607 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,11916638 0,12021565 ! regulation of membrane potential GO:0042391 164 93 0,000 0,11916638 0,12016526 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,11916638 0,12011492 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,12036923 0,12127653 ! female pregnancy GO:0007565 164 94 0,000 0,12036923 0,12122577 ! transcription initiation GO:0006352 153 94 0,000 0,12036923 0,12117505 ! regulation of T cell activation GO:0050863 158 94 0,000 0,12036923 0,12112437 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,12157047 0,122282 ! leukocyte differentiation GO:0002521 202 96 0,000 0,12277011 0,12343706 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,12277011 0,1233855 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,12277011 0,12333398 ! positive regulation of immune response GO:0050778 156 96 0,000 0,12277011 0,12328251 ! detection of stimulus GO:0051606 151 96 0,000 0,12277011 0,12323107 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,12396815 0,12438172 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,12396815 0,12432988 ! protein ubiquitination GO:0016567 217 97 0,000 0,12396815 0,12427807 ! hormone metabolic process GO:0042445 157 97 0,000 0,12396815 0,12422631 ! response to virus GO:0009615 160 98 0,000 0,1251646 0,12537303 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1251646 0,12532086 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,1251646 0,12526873 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,12635945 0,12641199 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,12635945 0,12635945