pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/704-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 1,332E-12 3,255E-09 ! ribosomal large subunit biogenesis GO:0042273 13 13 3,000 1,74E-09 2,125E-06 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 9,129E-07 7,434E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,277E-06 1,391E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 3,07E-06 1,5E-03 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 2,000 3,528E-06 1,436E-03 ! regulation of protein localization GO:0032880 188 97 3,000 7,788E-06 2,718E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,528E-05 4,667E-03 ! microvillus organization GO:0032528 8 5 1,000 1,634E-05 4,437E-03 GO:0030033|microvillus assembly, ! regulation of chondrocyte differentiation GO:0032330 16 5 1,000 1,634E-05 3,993E-03 ! somatic stem cell maintenance GO:0035019 15 5 1,000 1,634E-05 3,63E-03 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 2,000 1,658E-05 3,375E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 2,089E-05 3,926E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 2,000 2,248E-05 3,922E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 2,45E-05 3,99E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 2,45E-05 3,74E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of pseudopodium assembly GO:0031274 15 6 1,000 2,45E-05 3,52E-03 GO:0031272|regulation of pseudopodium assembly, ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 2,961E-05 4,019E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,961E-05 3,808E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,427E-05 4,186E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 3,427E-05 3,986E-03 ! establishment of tissue polarity GO:0007164 8 7 1,000 3,427E-05 3,805E-03 ! spindle checkpoint GO:0031577 16 7 1,000 3,427E-05 3,64E-03 ! negative regulation of nuclear division GO:0051784 15 7 1,000 3,427E-05 3,488E-03 GO:0045839|negative regulation of mitosis, ! ER overload response GO:0006983 13 8 1,000 4,565E-05 4,461E-03 ! regulation of intracellular transport GO:0032386 108 57 2,000 5,652E-05 5,31E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 7,325E-05 6,628E-03 ! lens development in camera-type eye GO:0002088 17 10 1,000 7,325E-05 6,391E-03 ! midbrain development GO:0030901 14 10 1,000 7,325E-05 6,17E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 8,767E-05 7,139E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 8,945E-05 7,049E-03 ! regulation of cell projection assembly GO:0060491 33 12 1,000 1,073E-04 8,188E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,073E-04 7,94E-03 ! histone acetylation GO:0016573 27 12 1,000 1,073E-04 7,706E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,073E-04 7,486E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 1,09E-04 7,397E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,702E-04 0,01123833 ! stem cell development GO:0048864 46 16 1,000 1,944E-04 0,0124955 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 1,944E-04 0,0121751 ! regulation of protein transport GO:0051223 165 87 2,000 1,992E-04 0,01216872 GO:0070201|regulation of establishment of protein localization, ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,201E-04 0,01311454 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,201E-04 0,01280228 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 2,474E-04 0,01405603 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 2,763E-04 0,01533999 ! proximal/distal pattern formation GO:0009954 33 19 1,000 2,763E-04 0,0149991 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,067E-04 0,01628993 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,067E-04 0,01594334 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 3,387E-04 0,01724025 ! stem cell differentiation GO:0048863 57 22 1,000 3,723E-04 0,01856194 ! peptidyl-serine modification GO:0018209 50 22 1,000 3,723E-04 0,0181907 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 3,723E-04 0,01783402 ! axis specification GO:0009798 43 23 1,000 4,074E-04 0,01914109 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 4,441E-04 0,02047033 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 4,823E-04 0,02182032 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 5,221E-04 0,02318977 ! osteoblast differentiation GO:0001649 63 26 1,000 5,221E-04 0,02277566 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 5,221E-04 0,02237609 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 5,221E-04 0,0219903 ! embryonic pattern specification GO:0009880 49 27 1,000 5,634E-04 0,02332776 ! positive regulation of cell projection organization GO:0031346 66 27 1,000 5,634E-04 0,02293896 ! protein amino acid acylation GO:0043543 59 28 1,000 6,062E-04 0,02427851 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 6,506E-04 0,02563519 ! somitogenesis GO:0001756 52 29 1,000 6,506E-04 0,02522828 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 7,439E-04 0,02839616 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 7,928E-04 0,0297987 ! mesoderm formation GO:0001707 73 32 1,000 7,928E-04 0,0293472 ! BMP signaling pathway GO:0030509 71 32 1,000 7,928E-04 0,02890918 ! hindbrain development GO:0030902 65 32 1,000 7,928E-04 0,02848405 ! formation of primary germ layer GO:0001704 76 34 1,000 8,953E-04 0,03169767 ! mesoderm morphogenesis GO:0048332 80 35 1,000 9,487E-04 0,0331112 ! cytokine production GO:0001816 68 36 1,000 1,004E-03 0,03453668 ! regulation of microtubule-based process GO:0032886 86 37 1,000 1,06E-03 0,03597349 ! glycogen metabolic process GO:0005977 63 38 1,000 1,118E-03 0,03742103 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 1,178E-03 0,03887875 ! glucan metabolic process GO:0044042 64 39 1,000 1,178E-03 0,03836036 GO:0006073|cellular glucan metabolic process, ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 1,365E-03 0,04387761 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 1,43E-03 0,04538298 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 1,43E-03 0,04480115 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 1,43E-03 0,04423405 ! segmentation GO:0035282 78 43 1,000 1,43E-03 0,04368112 ! energy reserve metabolic process GO:0006112 76 44 1,000 1,497E-03 0,04515905 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 1,497E-03 0,04460833 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 1,566E-03 0,04608275 ! mitochondrial transport GO:0006839 94 48 1,000 1,779E-03 0,05175345 ! positive regulation of DNA binding GO:0043388 83 48 1,000 1,779E-03 0,05114459 ! protein homooligomerization GO:0051260 84 49 1,000 1,854E-03 0,05265761 ! regulation of ossification GO:0030278 123 50 1,000 1,929E-03 0,05417663 ! regulation of cell projection organization GO:0031344 135 51 1,000 2,006E-03 0,05570132 ! positive regulation of binding GO:0051099 88 52 1,000 2,085E-03 0,0572314 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 2,085E-03 0,05659549 ! histone modification GO:0016570 104 52 1,000 2,085E-03 0,05597357 ! covalent chromatin modification GO:0016569 115 54 1,000 2,246E-03 0,0596511 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 2,414E-03 0,06340017 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 2,499E-03 0,06495322 ! regulation of bone remodeling GO:0046850 143 57 1,000 2,499E-03 0,06426951 ! positive regulation of cell migration GO:0030335 137 58 1,000 2,586E-03 0,06581734 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 2,586E-03 0,06513882 ! gastrulation GO:0007369 122 58 1,000 2,586E-03 0,06447413 ! regulation of tissue remodeling GO:0034103 146 58 1,000 2,586E-03 0,06382288 ! camera-type eye development GO:0043010 126 61 1,000 2,856E-03 0,06977811 ! regulation of mitosis GO:0007088 112 63 1,000 3,043E-03 0,07360975 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 3,043E-03 0,07288809 ! positive regulation of cell motion GO:0051272 157 65 1,000 3,236E-03 0,076748 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 3,434E-03 0,0806646 GO:0035113|embryonic appendage morphogenesis, ! cell projection assembly GO:0030031 138 68 1,000 3,535E-03 0,0822499 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 3,638E-03 0,08383715 ! lung development GO:0030324 165 69 1,000 3,638E-03 0,08305362 ! negative regulation of kinase activity GO:0033673 145 70 1,000 3,742E-03 0,08463522 ! cell cycle checkpoint GO:0000075 145 71 1,000 3,847E-03 0,08621863 ! appendage morphogenesis GO:0035107 150 72 1,000 3,954E-03 0,08780371 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 171 72 1,000 3,954E-03 0,08701268 ! appendage development GO:0048736 151 73 1,000 4,062E-03 0,08859221 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 4,171E-03 0,09017328 ! negative regulation of transferase activity GO:0051348 155 74 1,000 4,171E-03 0,08938229 ! respiratory system development GO:0060541 175 74 1,000 4,171E-03 0,08860505 ! regulation of transcription factor activity GO:0051090 137 75 1,000 4,282E-03 0,09017379 GO:0090046|regulation of transcription regulator activity, ! eye development GO:0001654 155 75 1,000 4,282E-03 0,08940307 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 4,507E-03 0,09331573 ! protein oligomerization GO:0051259 149 79 1,000 4,738E-03 0,09727352 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 4,856E-03 0,09885518 ! negative regulation of organelle organization GO:0010639 181 80 1,000 4,856E-03 0,0980382 ! response to hypoxia GO:0001666 178 81 1,000 4,975E-03 0,09961449 ! regulation of peptidase activity GO:0052547 150 82 1,000 5,095E-03 0,1011917 ! response to oxygen levels GO:0070482 183 83 1,000 5,216E-03 0,10276973 ! regulation of DNA binding GO:0051101 167 89 1,000 5,973E-03 0,11674038 ! regulation of cell cycle process GO:0010564 161 90 1,000 6,104E-03 0,11834896 ! ossification GO:0001503 205 91 1,000 6,236E-03 0,1199573 ! bone development GO:0060348 206 92 1,000 6,369E-03 0,12156536 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 6,454E-03 0,122235 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 6,454E-03 0,12129473 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 6,454E-03 0,12036881 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 6,454E-03 0,11945693 ! positive regulation of helicase activity GO:0051096 12 5 0,000 6,454E-03 0,11855876 ! neuron fate determination GO:0048664 7 5 0,000 6,454E-03 0,11767399 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 6,454E-03 0,11680233 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 6,454E-03 0,11594349 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 6,454E-03 0,11509719 ! polyol transport GO:0015791 12 5 0,000 6,454E-03 0,11426315 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 6,454E-03 0,11344111 ! response to superoxide GO:0000303 10 5 0,000 6,454E-03 0,11263082 ! negative regulation of bone resorption GO:0045779 10 5 0,000 6,454E-03 0,11183202 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 6,454E-03 0,11104447 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 6,454E-03 0,11026793 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 6,454E-03 0,10950218 ! female meiosis GO:0007143 10 5 0,000 6,454E-03 0,108747 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 6,454E-03 0,10800215 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 6,454E-03 0,10726745 ! hypothalamus development GO:0021854 9 5 0,000 6,454E-03 0,10654267 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 6,454E-03 0,10582761 ! cobalt ion transport GO:0006824 11 5 0,000 6,454E-03 0,1051221 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 6,454E-03 0,10442592 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 6,454E-03 0,10373891 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 6,454E-03 0,10306088 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 6,454E-03 0,10239165 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 6,454E-03 0,10173106 ! embryonic camera-type eye development GO:0031076 12 5 0,000 6,454E-03 0,10107894 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 6,454E-03 0,10043512 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 6,454E-03 0,09979946 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 6,454E-03 0,09917179 ! transposition GO:0032196 9 5 0,000 6,454E-03 0,09855197 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 6,454E-03 0,09793984 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 6,454E-03 0,09733528 ! negative chemotaxis GO:0050919 16 5 0,000 6,454E-03 0,09673813 ! positive regulation of histone modification GO:0031058 6 5 0,000 6,454E-03 0,09614826 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 6,454E-03 0,09556554 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 6,454E-03 0,09498985 ! behavioral response to pain GO:0048266 10 5 0,000 6,454E-03 0,09442105 ! clathrin coat assembly GO:0048268 15 5 0,000 6,454E-03 0,09385902 ! Notch receptor processing GO:0007220 11 5 0,000 6,454E-03 0,09330364 ! regulation of dopamine uptake GO:0051584 9 5 0,000 6,454E-03 0,09275479 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 6,454E-03 0,09221237 ! micturition GO:0060073 9 5 0,000 6,454E-03 0,09167625 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 6,454E-03 0,09114633 ! copulation GO:0007620 9 5 0,000 6,454E-03 0,0906225 ! glial cell fate commitment GO:0021781 14 5 0,000 6,454E-03 0,09010465 ! protein maturation by protein folding GO:0022417 14 5 0,000 6,454E-03 0,0895927 ! bioluminescence GO:0008218 9 5 0,000 6,454E-03 0,08908652 ! spermidine metabolic process GO:0008216 7 5 0,000 6,454E-03 0,08858604 ! regulation of potassium ion transport GO:0043266 10 5 0,000 6,454E-03 0,08809114 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 6,454E-03 0,08760175 ! apoptotic cell clearance GO:0043277 23 5 0,000 6,454E-03 0,08711776 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 6,454E-03 0,08663909 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 6,454E-03 0,08616565 ! lipoprotein particle clearance GO:0034381 10 5 0,000 6,454E-03 0,08569736 ! grooming behavior GO:0007625 6 5 0,000 6,454E-03 0,08523413 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 6,454E-03 0,08477588 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 6,454E-03 0,08432254 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 6,454E-03 0,08387401 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 6,454E-03 0,08343024 ! response to protozoan GO:0001562 13 5 0,000 6,454E-03 0,08299113 ! positive regulation of glycolysis GO:0045821 13 5 0,000 6,454E-03 0,08255662 ! lymph vessel development GO:0001945 10 5 0,000 6,454E-03 0,08212664 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 6,454E-03 0,08170111 ! endochondral ossification GO:0001958 17 5 0,000 6,454E-03 0,08127997 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 6,454E-03 0,08086315 ! single strand break repair GO:0000012 8 5 0,000 6,454E-03 0,08045058 ! parathyroid gland development GO:0060017 14 5 0,000 6,454E-03 0,08004221 ! anagen GO:0042640 7 5 0,000 6,454E-03 0,07963795 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 6,454E-03 0,07923776 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 6,454E-03 0,07884157 ! cytokine secretion GO:0050663 15 5 0,000 6,454E-03 0,07844933 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 6,454E-03 0,07806096 ! ceramide catabolic process GO:0046514 7 5 0,000 6,454E-03 0,07767643 ! skeletal myofibril assembly GO:0014866 12 5 0,000 6,454E-03 0,07729566 ! smooth muscle tissue development GO:0048745 32 5 0,000 6,454E-03 0,07691861 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 6,454E-03 0,07654522 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 6,454E-03 0,07617543 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 6,454E-03 0,0758092 ! cardiac muscle fiber development GO:0048739 12 5 0,000 6,454E-03 0,07544648 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 6,454E-03 0,07508721 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 6,454E-03 0,07473135 ! neutrophil mediated immunity GO:0002446 7 5 0,000 6,454E-03 0,07437884 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 6,454E-03 0,07402965 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 6,454E-03 0,07368371 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 6,454E-03 0,073341 ! glycine biosynthetic process GO:0006545 7 5 0,000 6,454E-03 0,07300146 ! valine metabolic process GO:0006573 12 5 0,000 6,454E-03 0,07266504 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 6,454E-03 0,07233172 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 6,454E-03 0,07200144 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 6,454E-03 0,07167416 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 6,454E-03 0,07134984 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 6,454E-03 0,07102844 ! polyol catabolic process GO:0046174 9 5 0,000 6,454E-03 0,07070993 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 6,454E-03 0,07039426 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 6,454E-03 0,0700814 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 6,454E-03 0,0697713 ! muscle cell migration GO:0014812 8 5 0,000 6,454E-03 0,06946394 ! mitochondrial fission GO:0000266 8 5 0,000 6,454E-03 0,06915927 ! sister chromatid cohesion GO:0007062 15 5 0,000 6,454E-03 0,06885727 ! response to tumor necrosis factor GO:0034612 10 5 0,000 6,454E-03 0,06855789 ! mRNA transcription GO:0009299 10 5 0,000 6,454E-03 0,0682611 ! nerve growth factor processing GO:0032455 9 5 0,000 6,454E-03 0,06796687 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 6,454E-03 0,06767517 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 6,454E-03 0,06738596 ! anaerobic glycolysis GO:0019642 6 5 0,000 6,454E-03 0,06709921 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 6,454E-03 0,06681489 ! monocyte activation GO:0042117 10 5 0,000 6,454E-03 0,06653297 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 6,454E-03 0,06625342 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 6,454E-03 0,06597621 ! response to food GO:0032094 6 5 0,000 6,454E-03 0,06570131 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 6,454E-03 0,06542869 ! positive regulation of transporter activity GO:0032411 8 5 0,000 6,454E-03 0,06515832 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 6,454E-03 0,06489018 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 6,454E-03 0,06462424 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 6,454E-03 0,06436047 ! forebrain neuron development GO:0021884 13 5 0,000 6,454E-03 0,06409884 ! lipoprotein catabolic process GO:0042159 11 5 0,000 6,454E-03 0,06383933 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 6,454E-03 0,06358191 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 6,454E-03 0,06332656 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 6,454E-03 0,06307326 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 6,454E-03 0,06282197 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 6,454E-03 0,06257268 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 6,454E-03 0,06232535 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 6,454E-03 0,06207998 ! lipid glycosylation GO:0030259 7 5 0,000 6,454E-03 0,06183653 ! nucleobase transport GO:0015851 6 5 0,000 6,454E-03 0,06159498 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 6,454E-03 0,06135531 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 6,454E-03 0,0611175 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 6,454E-03 0,06088152 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 6,454E-03 0,06064736 ! basic amino acid transport GO:0015802 12 5 0,000 6,454E-03 0,060415 ! cellular glucose homeostasis GO:0001678 6 5 0,000 6,454E-03 0,06018441 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 6,454E-03 0,05995557 ! actin nucleation GO:0045010 11 5 0,000 6,454E-03 0,05972846 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 6,454E-03 0,05950307 ! depurination GO:0045007 5 5 0,000 6,454E-03 0,05927938 ! depyrimidination GO:0045008 10 5 0,000 6,454E-03 0,05905736 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 6,454E-03 0,05883699 ! regulation of centrosome cycle GO:0046605 7 5 0,000 6,454E-03 0,05861827 ! G2/M transition checkpoint GO:0031576 8 5 0,000 6,454E-03 0,05840117 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 6,454E-03 0,05818566 ! zinc ion homeostasis GO:0055069 9 5 0,000 6,454E-03 0,05797174 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 6,454E-03 0,05775939 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 6,454E-03 0,05754859 ! forebrain morphogenesis GO:0048853 13 5 0,000 6,454E-03 0,05733933 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 6,454E-03 0,05713157 ! activated T cell proliferation GO:0050798 16 5 0,000 6,454E-03 0,05692532 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 6,454E-03 0,05672056 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 6,454E-03 0,05651726 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 6,454E-03 0,05631541 ! positive regulation of organ growth GO:0046622 6 5 0,000 6,454E-03 0,056115 ! gamma-delta T cell activation GO:0046629 6 5 0,000 6,454E-03 0,05591601 ! response to arsenic GO:0046685 11 5 0,000 6,454E-03 0,05571843 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 6,454E-03 0,05552223 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 6,454E-03 0,05532742 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 6,454E-03 0,05513397 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 6,454E-03 0,05494186 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 6,454E-03 0,05475109 ! response to mercury ion GO:0046689 8 5 0,000 6,454E-03 0,05456164 ! response to cadmium ion GO:0046686 7 5 0,000 6,454E-03 0,0543735 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 6,454E-03 0,05418665 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 6,454E-03 0,05400108 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 6,454E-03 0,05381677 ! bile acid biosynthetic process GO:0006699 7 5 0,000 6,454E-03 0,05363372 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 6,454E-03 0,05345191 ! ganglioside catabolic process GO:0006689 12 5 0,000 6,454E-03 0,05327133 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 6,454E-03 0,05309197 ! decidualization GO:0046697 11 5 0,000 6,454E-03 0,05291381 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 6,454E-03 0,05273684 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 6,454E-03 0,05256105 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 6,454E-03 0,05238643 ! embryonic cleavage GO:0040016 6 5 0,000 6,454E-03 0,05221296 ! peroxisome fission GO:0016559 5 5 0,000 6,454E-03 0,05204064 ! histone demethylation GO:0016577 13 5 0,000 6,454E-03 0,05186946 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 6,454E-03 0,05169939 ! mitotic recombination GO:0006312 9 5 0,000 6,454E-03 0,05153044 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 6,454E-03 0,05136259 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 6,454E-03 0,05119583 ! metaphase plate congression GO:0051310 7 5 0,000 6,454E-03 0,05103014 ! regulation of sterol transport GO:0032371 7 5 0,000 6,454E-03 0,05086553 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 6,454E-03 0,05070198 ! enteric nervous system development GO:0048484 8 5 0,000 6,454E-03 0,05053947 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 6,454E-03 0,050378 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 6,454E-03 0,05021756 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 6,454E-03 0,05005814 ! muscle cell proliferation GO:0033002 12 5 0,000 6,454E-03 0,04989973 ! skeletal muscle regeneration GO:0043403 8 5 0,000 6,454E-03 0,04974232 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 6,454E-03 0,04958589 ! B cell homeostasis GO:0001782 13 5 0,000 6,454E-03 0,04943045 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 6,454E-03 0,04927598 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 6,454E-03 0,04912248 ! metaphase GO:0051323 11 5 0,000 6,454E-03 0,04896992 ! melatonin biosynthetic process GO:0030187 7 5 0,000 6,454E-03 0,04881831 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 6,454E-03 0,04866764 ! cellular response to nutrient GO:0031670 8 5 0,000 6,454E-03 0,04851789 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 6,454E-03 0,04836906 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 6,454E-03 0,04822115 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 6,454E-03 0,04807413 ! regulation of hair follicle development GO:0051797 10 5 0,000 6,454E-03 0,04792801 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 6,454E-03 0,04778277 ! response to redox state GO:0051775 6 5 0,000 6,454E-03 0,04763841 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 6,454E-03 0,04749492 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 6,454E-03 0,0473523 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 6,454E-03 0,04721052 ! brown fat cell differentiation GO:0050873 7 5 0,000 6,454E-03 0,0470696 ! regulation of telomerase activity GO:0051972 7 5 0,000 6,454E-03 0,04692951 ! galactolipid metabolic process GO:0019374 7 5 0,000 6,454E-03 0,04679025 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 6,454E-03 0,04665182 ! porphyrin catabolic process GO:0006787 12 5 0,000 6,454E-03 0,0465142 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 6,454E-03 0,0463774 ! striatum development GO:0021756 14 5 0,000 6,454E-03 0,04624139 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 6,454E-03 0,04610618 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 6,454E-03 0,04597176 ! glial cell migration GO:0008347 10 5 0,000 6,454E-03 0,04583812 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 6,454E-03 0,04570526 ! neural plate morphogenesis GO:0001839 7 5 0,000 6,454E-03 0,04557316 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 6,454E-03 0,04544183 ! T cell activation during immune response GO:0002286 9 5 0,000 6,454E-03 0,04531125 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 6,454E-03 0,04518142 ! negative regulation of lipase activity GO:0060192 8 5 0,000 6,454E-03 0,04505233 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 6,454E-03 0,04492397 ! neuroprotection GO:0043526 8 5 0,000 6,454E-03 0,04479635 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 6,454E-03 0,04466945 ! regulation of sensory perception GO:0051931 8 5 0,000 6,454E-03 0,04454326 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 6,454E-03 0,04441779 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 6,454E-03 0,04429302 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 6,454E-03 0,04416895 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 6,454E-03 0,04404557 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 6,454E-03 0,04392288 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 6,454E-03 0,04380087 ! sequestering of calcium ion GO:0051208 7 5 0,000 6,454E-03 0,04367954 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 6,454E-03 0,04355888 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 6,454E-03 0,04343888 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 6,454E-03 0,04331955 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 6,454E-03 0,04320086 ! spindle assembly GO:0051225 6 5 0,000 6,454E-03 0,04308283 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 6,454E-03 0,04296543 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 6,454E-03 0,04284868 ! protein palmitoylation GO:0018345 12 5 0,000 6,454E-03 0,04273256 ! drug metabolic process GO:0017144 7 5 0,000 6,454E-03 0,04261707 ! stem cell division GO:0017145 11 5 0,000 6,454E-03 0,0425022 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 6,454E-03 0,04238794 ! organ regeneration GO:0031100 7 5 0,000 6,454E-03 0,0422743 ! carnitine metabolic process GO:0009437 8 5 0,000 6,454E-03 0,04216127 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 6,454E-03 0,04204884 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 7,197E-03 0,04675905 ! forebrain development GO:0030900 210 98 1,000 7,197E-03 0,04663502 ! skeletal muscle tissue development GO:0007519 223 100 1,000 7,483E-03 0,04836016 GO:0060538|skeletal muscle organ development, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 7,74E-03 0,04989448 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 7,74E-03 0,04976318 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 7,74E-03 0,04963257 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 7,74E-03 0,04950264 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 7,74E-03 0,04937339 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 7,74E-03 0,04924481 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 7,74E-03 0,04911691 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 7,74E-03 0,04898966 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 7,74E-03 0,04886307 ! response to oxygen radical GO:0000305 11 6 0,000 7,74E-03 0,04873714 ! positive regulation of axon extension GO:0045773 13 6 0,000 7,74E-03 0,04861185 ! myoblast cell fate commitment GO:0048625 18 6 0,000 7,74E-03 0,0484872 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 7,74E-03 0,04836319 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 7,74E-03 0,04823982 ! regulation of interferon-beta production GO:0032648 8 6 0,000 7,74E-03 0,04811707 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 7,74E-03 0,04799495 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 7,74E-03 0,04787344 ! forebrain regionalization GO:0021871 9 6 0,000 7,74E-03 0,04775255 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 7,74E-03 0,04763226 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 7,74E-03 0,04751258 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 7,74E-03 0,0473935 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 7,74E-03 0,04727502 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 7,74E-03 0,04715713 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 7,74E-03 0,04703982 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 7,74E-03 0,0469231 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 7,74E-03 0,04680695 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 7,74E-03 0,04669138 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 7,74E-03 0,04657638 ! malate metabolic process GO:0006108 13 6 0,000 7,74E-03 0,04646194 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 7,74E-03 0,04634806 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 7,74E-03 0,04623474 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 7,74E-03 0,04612197 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 7,74E-03 0,04600975 ! protein refolding GO:0042026 15 6 0,000 7,74E-03 0,04589808 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 7,74E-03 0,04578695 ! opsonization GO:0008228 8 6 0,000 7,74E-03 0,04567635 ! mating behavior GO:0007617 7 6 0,000 7,74E-03 0,04556629 ! erythrocyte maturation GO:0043249 8 6 0,000 7,74E-03 0,04545675 ! embryonic hemopoiesis GO:0035162 16 6 0,000 7,74E-03 0,04534774 ! protein amino acid dealkylation GO:0008214 15 6 0,000 7,74E-03 0,04523925 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 7,74E-03 0,04513129 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 7,74E-03 0,04502383 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 7,74E-03 0,04491688 ! response to interferon-gamma GO:0034341 16 6 0,000 7,74E-03 0,04481045 ! toxin metabolic process GO:0009404 11 6 0,000 7,74E-03 0,04470451 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 7,74E-03 0,04459908 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 7,74E-03 0,04449414 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 7,74E-03 0,04438969 ! nuclear migration GO:0007097 13 6 0,000 7,74E-03 0,04428573 ! cGMP-mediated signaling GO:0019934 14 6 0,000 7,74E-03 0,04418226 ! dorsal spinal cord development GO:0021516 10 6 0,000 7,74E-03 0,04407927 ! activation of MAPKKK activity GO:0000185 12 6 0,000 7,74E-03 0,04397676 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 7,74E-03 0,04387473 ! thymic T cell selection GO:0045061 16 6 0,000 7,74E-03 0,04377317 ! sphingoid catabolic process GO:0046521 8 6 0,000 7,74E-03 0,04367207 ! protein lipoylation GO:0009249 10 6 0,000 7,74E-03 0,04357145 ! transepithelial chloride transport GO:0030321 12 6 0,000 7,74E-03 0,04347128 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 7,74E-03 0,04337158 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 7,74E-03 0,04327233 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 7,74E-03 0,04317354 ! glutamate catabolic process GO:0006538 12 6 0,000 7,74E-03 0,04307519 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 7,74E-03 0,04297729 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 7,74E-03 0,04287984 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 7,74E-03 0,04278282 ! hyperosmotic response GO:0006972 10 6 0,000 7,74E-03 0,04268625 ! L-serine biosynthetic process GO:0006564 7 6 0,000 7,74E-03 0,04259011 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 7,74E-03 0,0424944 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 7,74E-03 0,04239912 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 7,74E-03 0,04230427 ! urea metabolic process GO:0019627 7 6 0,000 7,74E-03 0,04220984 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 7,74E-03 0,04211583 ! neutrophil activation GO:0042119 7 6 0,000 7,74E-03 0,04202224 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 7,74E-03 0,04192907 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 7,74E-03 0,0418363 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 7,74E-03 0,04174395 ! paraxial mesoderm development GO:0048339 16 6 0,000 7,74E-03 0,041652 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 7,74E-03 0,04156046 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 7,74E-03 0,04146932 ! neuron apoptosis GO:0051402 15 6 0,000 7,74E-03 0,04137857 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 7,74E-03 0,04128823 ! T cell mediated immunity GO:0002456 17 6 0,000 7,74E-03 0,04119828 ! negative regulation of platelet activation GO:0010544 9 6 0,000 7,74E-03 0,04110871 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 7,74E-03 0,04101954 ! carnitine transport GO:0015879 10 6 0,000 7,74E-03 0,04093075 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 7,74E-03 0,04084235 ! positive regulation of exocytosis GO:0045921 11 6 0,000 7,74E-03 0,04075433 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 7,74E-03 0,04066668 ! early endosome to late endosome transport GO:0045022 16 6 0,000 7,74E-03 0,04057942 ! 5S class rRNA transcription GO:0042791 13 6 0,000 7,74E-03 0,04049252 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 7,74E-03 0,040406 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 7,74E-03 0,04031985 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 7,74E-03 0,04023406 ! sodium ion homeostasis GO:0055078 12 6 0,000 7,74E-03 0,04014864 ! establishment of spindle localization GO:0051293 16 6 0,000 7,74E-03 0,04006358 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 7,74E-03 0,03997888 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 7,74E-03 0,03989453 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 7,74E-03 0,03981054 ! response to UV-C GO:0010225 14 6 0,000 7,74E-03 0,03972691 ! astrocyte development GO:0014002 16 6 0,000 7,74E-03 0,03964362 ! protein targeting to lysosome GO:0006622 12 6 0,000 7,74E-03 0,03956069 ! purine base biosynthetic process GO:0009113 17 6 0,000 7,74E-03 0,0394781 ! interaction with symbiont GO:0051702 14 6 0,000 7,74E-03 0,03939585 ! regulation of dendrite development GO:0050773 16 6 0,000 7,74E-03 0,03931395 ! peptidyl-arginine modification GO:0018195 13 6 0,000 7,74E-03 0,03923238 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 7,74E-03 0,03915116 ! response to copper ion GO:0046688 10 6 0,000 7,74E-03 0,03907027 ! response to exogenous dsRNA GO:0043330 13 6 0,000 7,74E-03 0,03898971 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 7,74E-03 0,03890948 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 7,74E-03 0,03882959 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 7,74E-03 0,03875002 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 7,74E-03 0,03867077 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 7,74E-03 0,03859185 ! regulation of dopamine secretion GO:0014059 14 6 0,000 7,74E-03 0,03851326 ! nucleoside catabolic process GO:0009164 10 6 0,000 7,74E-03 0,03843498 ! hair follicle maturation GO:0048820 8 6 0,000 7,74E-03 0,03835702 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 7,74E-03 0,03827937 ! Schwann cell development GO:0014044 15 6 0,000 7,74E-03 0,03820204 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 7,74E-03 0,03812502 ! response to pheromone GO:0019236 6 6 0,000 7,74E-03 0,03804831 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 7,74E-03 0,0379719 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 7,74E-03 0,03789581 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 7,74E-03 0,03782002 ! base conversion or substitution editing GO:0016553 6 6 0,000 7,74E-03 0,03774453 ! subpallium development GO:0021544 15 6 0,000 7,74E-03 0,03766934 ! neural tube patterning GO:0021532 8 6 0,000 7,74E-03 0,03759445 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 7,74E-03 0,03751986 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 7,74E-03 0,03744556 ! maintenance of organ identity GO:0048496 9 6 0,000 7,74E-03 0,03737156 ! G2 phase GO:0051319 16 6 0,000 7,74E-03 0,03729785 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 7,74E-03 0,03722443 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 7,74E-03 0,03715129 ! oxygen homeostasis GO:0032364 10 6 0,000 7,74E-03 0,03707845 ! establishment of planar polarity GO:0001736 7 6 0,000 7,74E-03 0,03700589 ! regulation of mast cell activation GO:0033003 13 6 0,000 7,74E-03 0,03693361 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 7,74E-03 0,03686161 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 7,74E-03 0,0367899 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 7,74E-03 0,03671846 ! receptor internalization GO:0031623 11 6 0,000 7,74E-03 0,0366473 ! plasminogen activation GO:0031639 9 6 0,000 7,74E-03 0,03657642 ! neutrophil homeostasis GO:0001780 11 6 0,000 7,74E-03 0,03650581 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 7,74E-03 0,03643547 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 7,74E-03 0,0363654 ! protein deubiquitination GO:0016579 16 6 0,000 7,74E-03 0,0362956 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 7,74E-03 0,03622607 ! protein destabilization GO:0031648 9 6 0,000 7,74E-03 0,0361568 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 7,74E-03 0,0360878 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 7,74E-03 0,03601906 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 7,74E-03 0,03595059 ! regulation of viral transcription GO:0046782 11 6 0,000 7,74E-03 0,03588237 ! progesterone metabolic process GO:0042448 12 6 0,000 7,74E-03 0,03581441 ! negative regulation of axon extension GO:0030517 24 6 0,000 7,74E-03 0,03574671 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 7,74E-03 0,03567926 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 7,74E-03 0,03561207 ! triglyceride catabolic process GO:0019433 10 6 0,000 7,74E-03 0,03554513 ! determination of adult lifespan GO:0008340 17 6 0,000 7,74E-03 0,03547844 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 7,74E-03 0,035412 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 7,74E-03 0,03534581 ! neural plate development GO:0001840 9 6 0,000 7,74E-03 0,03527987 ! catecholamine transport GO:0051937 9 6 0,000 7,74E-03 0,03521417 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 7,74E-03 0,03514871 ! sensory cilium assembly GO:0035058 10 6 0,000 7,74E-03 0,0350835 ! organ or tissue specific immune response GO:0002251 8 6 0,000 7,74E-03 0,03501853 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 7,74E-03 0,0349538 ! maternal placenta development GO:0001893 12 6 0,000 7,74E-03 0,03488931 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 7,74E-03 0,03482506 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 7,74E-03 0,03476104 ! negative regulation of B cell activation GO:0050869 14 6 0,000 7,74E-03 0,03469726 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 7,74E-03 0,03463372 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 7,74E-03 0,0345704 ! positive regulation of coagulation GO:0050820 13 6 0,000 7,74E-03 0,03450731 ! cellular anion homeostasis GO:0030002 11 6 0,000 7,74E-03 0,03444446 GO:0055081|anion homeostasis, ! tRNA transcription GO:0009304 17 7 0,000 9,025E-03 0,04008677 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 9,025E-03 0,04001402 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 9,025E-03 0,03994153 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,025E-03 0,0398693 ! regulation of helicase activity GO:0051095 16 7 0,000 9,025E-03 0,03979734 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 9,025E-03 0,03972563 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 9,025E-03 0,03965418 ! sleep GO:0030431 16 7 0,000 9,025E-03 0,03958299 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,025E-03 0,03951205 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 9,025E-03 0,03944137 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,025E-03 0,03937094 ! prostate gland development GO:0030850 14 7 0,000 9,025E-03 0,03930076 ! nucleotide-sugar transport GO:0015780 11 7 0,000 9,025E-03 0,03923083 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,025E-03 0,03916114 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,025E-03 0,03909171 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 9,025E-03 0,03902252 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,025E-03 0,03895358 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 9,025E-03 0,03888487 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 9,025E-03 0,03881642 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,025E-03 0,0387482 ! SMAD protein complex assembly GO:0007183 13 7 0,000 9,025E-03 0,03868022 ! glycolipid transport GO:0046836 11 7 0,000 9,025E-03 0,03861248 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,025E-03 0,03854497 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 9,025E-03 0,0384777 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 9,025E-03 0,03841067 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 9,025E-03 0,03834387 ! mRNA stabilization GO:0048255 18 7 0,000 9,025E-03 0,0382773 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 9,025E-03 0,03821096 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 9,025E-03 0,03814485 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 9,025E-03 0,03807897 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 9,025E-03 0,03801332 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,025E-03 0,03794789 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,025E-03 0,03788269 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,025E-03 0,03781771 ! lipoprotein transport GO:0042953 14 7 0,000 9,025E-03 0,03775295 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 9,025E-03 0,03768842 ! rhythmic behavior GO:0007622 17 7 0,000 9,025E-03 0,0376241 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 9,025E-03 0,03756001 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 9,025E-03 0,03749613 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 9,025E-03 0,03743247 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 9,025E-03 0,03736902 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,025E-03 0,03730579 ! regulation of odontogenesis GO:0042481 14 7 0,000 9,025E-03 0,03724278 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,025E-03 0,03717997 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 9,025E-03 0,03711738 ! mechanosensory behavior GO:0007638 16 7 0,000 9,025E-03 0,037055 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 9,025E-03 0,03699283 ! positive regulation of isotype switching GO:0045830 17 7 0,000 9,025E-03 0,03693086 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 9,025E-03 0,0368691 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 9,025E-03 0,03680755 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,025E-03 0,03674621 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,025E-03 0,03668507 ! spinal cord patterning GO:0021511 14 7 0,000 9,025E-03 0,03662413 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 9,025E-03 0,03656339 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 9,025E-03 0,03650285 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,025E-03 0,03644252 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 9,025E-03 0,03638238 ! adrenal gland development GO:0030325 17 7 0,000 9,025E-03 0,03632244 ! cysteine metabolic process GO:0006534 13 7 0,000 9,025E-03 0,0362627 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 9,025E-03 0,03620316 ! ovulation GO:0030728 10 7 0,000 9,025E-03 0,03614381 ! adenohypophysis development GO:0021984 11 7 0,000 9,025E-03 0,03608465 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 9,025E-03 0,03602569 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 9,025E-03 0,03596692 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 9,025E-03 0,03590835 ! microtubule nucleation GO:0007020 21 7 0,000 9,025E-03 0,03584996 ! proline biosynthetic process GO:0006561 10 7 0,000 9,025E-03 0,03579176 ! tryptophan metabolic process GO:0006568 11 7 0,000 9,025E-03 0,03573375 ! thyroid hormone generation GO:0006590 13 7 0,000 9,025E-03 0,03567593 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 9,025E-03 0,03561829 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 9,025E-03 0,03556085 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,025E-03 0,03550358 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 9,025E-03 0,0354465 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 9,025E-03 0,03538961 ! galactose metabolic process GO:0006012 13 7 0,000 9,025E-03 0,03533289 ! vesicle fusion GO:0006906 20 7 0,000 9,025E-03 0,03527636 ! response to dietary excess GO:0002021 8 7 0,000 9,025E-03 0,03522001 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,025E-03 0,03516383 ! intracellular pH reduction GO:0051452 13 7 0,000 9,025E-03 0,03510784 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,025E-03 0,03505203 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 9,025E-03 0,03499639 ! organ growth GO:0035265 15 7 0,000 9,025E-03 0,03494093 ! nucleoside transport GO:0015858 11 7 0,000 9,025E-03 0,03488564 ! nucleoside salvage GO:0043174 11 7 0,000 9,025E-03 0,03483053 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 9,025E-03 0,03477559 ! male sex determination GO:0030238 15 7 0,000 9,025E-03 0,03472083 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 9,025E-03 0,03466623 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 9,025E-03 0,03461181 ! parturition GO:0007567 16 7 0,000 9,025E-03 0,03455756 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 9,025E-03 0,03450348 ! rRNA modification GO:0000154 14 7 0,000 9,025E-03 0,03444957 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 9,025E-03 0,03439583 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 9,025E-03 0,03434225 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 9,025E-03 0,03428884 ! monocyte differentiation GO:0030224 16 7 0,000 9,025E-03 0,0342356 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 9,025E-03 0,03418252 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,025E-03 0,0341296 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 9,025E-03 0,03407685 ! hyaluronan metabolic process GO:0030212 9 7 0,000 9,025E-03 0,03402427 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 9,025E-03 0,03397184 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,025E-03 0,03391958 ! fibrinolysis GO:0042730 11 7 0,000 9,025E-03 0,03386747 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 9,025E-03 0,03381553 ! skeletal muscle contraction GO:0003009 8 7 0,000 9,025E-03 0,03376374 ! eating behavior GO:0042755 8 7 0,000 9,025E-03 0,03371212 ! B cell lineage commitment GO:0002326 21 7 0,000 9,025E-03 0,03366065 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,025E-03 0,03360934 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 9,025E-03 0,03355818 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 9,025E-03 0,03350718 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,025E-03 0,03345633 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 9,025E-03 0,03340564 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,025E-03 0,0333551 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 9,025E-03 0,03330472 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 9,025E-03 0,03325449 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 9,025E-03 0,0332044 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 9,025E-03 0,03315447 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,025E-03 0,03310469 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 9,025E-03 0,03305506 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,025E-03 0,03300558 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,025E-03 0,03295624 ! histone ubiquitination GO:0016574 9 7 0,000 9,025E-03 0,03290705 ! regulation of meiosis GO:0040020 12 7 0,000 9,025E-03 0,03285801 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 9,025E-03 0,03280911 ! T cell lineage commitment GO:0002360 16 7 0,000 9,025E-03 0,03276036 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 9,025E-03 0,03271176 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,025E-03 0,03266329 ! membrane to membrane docking GO:0022614 14 7 0,000 9,025E-03 0,03261498 ! transcription termination GO:0006353 14 7 0,000 9,025E-03 0,0325668 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,025E-03 0,03251877 ! anaphase GO:0051322 18 7 0,000 9,025E-03 0,03247087 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 9,025E-03 0,03242312 ! axonal fasciculation GO:0007413 19 7 0,000 9,025E-03 0,03237551 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 9,025E-03 0,03232804 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 9,025E-03 0,03228071 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 9,025E-03 0,03223351 ! diuresis GO:0030146 12 7 0,000 9,025E-03 0,03218646 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,025E-03 0,03213954 ! thiamin metabolic process GO:0006772 7 7 0,000 9,025E-03 0,03209276 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,025E-03 0,03204611 ! antibiotic transport GO:0042891 9 7 0,000 9,025E-03 0,0319996 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,025E-03 0,03195322 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 9,025E-03 0,03190698 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 9,025E-03 0,03186087 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 9,025E-03 0,0318149 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 9,025E-03 0,03176905 ! melanin biosynthetic process GO:0042438 10 7 0,000 9,025E-03 0,03172334 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 9,025E-03 0,03167776 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,025E-03 0,03163232 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,025E-03 0,031587 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 9,025E-03 0,03154181 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 9,025E-03 0,03149675 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 9,025E-03 0,03145182 ! endosome to lysosome transport GO:0008333 12 7 0,000 9,025E-03 0,03140701 ! protein modification by small protein removal GO:0070646 19 7 0,000 9,025E-03 0,03136234 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 9,025E-03 0,03131779 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 9,025E-03 0,03127337 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 9,025E-03 0,03122907 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 9,025E-03 0,0311849 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,025E-03 0,03114085 ! muscle adaptation GO:0043500 13 7 0,000 9,025E-03 0,03109693 ! embryonic heart tube development GO:0035050 14 7 0,000 9,025E-03 0,03105313 ! retina homeostasis GO:0001895 12 7 0,000 9,025E-03 0,03100946 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 9,025E-03 0,0309659 ! protein amino acid prenylation GO:0018346 19 7 0,000 9,025E-03 0,03092247 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 9,025E-03 0,03087917 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 9,025E-03 0,03083598 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,0103076 0,03516965 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,0103076 0,03512059 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,0103076 0,03507168 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,0103076 0,0350229 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,0103076 0,03497426 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,0103076 0,03492575 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0103076 0,03487738 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0103076 0,03482914 ! male meiosis GO:0007140 9 8 0,000 0,0103076 0,03478103 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,0103076 0,03473306 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,0103076 0,03468522 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,0103076 0,03463751 ! meiotic prophase I GO:0007128 14 8 0,000 0,0103076 0,03458993 ! response to zinc ion GO:0010043 12 8 0,000 0,0103076 0,03454248 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,0103076 0,03449516 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0103076 0,03444797 ! oligopeptide transport GO:0006857 16 8 0,000 0,0103076 0,03440091 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,0103076 0,03435398 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,0103076 0,03430718 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,0103076 0,0342605 ! signal peptide processing GO:0006465 12 8 0,000 0,0103076 0,03421395 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,0103076 0,03416753 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,0103076 0,03412123 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0103076 0,03407506 ! succinate metabolic process GO:0006105 17 8 0,000 0,0103076 0,03402901 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,0103076 0,03398309 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,0103076 0,03393729 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0103076 0,03389161 ! estrogen metabolic process GO:0008210 17 8 0,000 0,0103076 0,03384606 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,0103076 0,03380063 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0103076 0,03375532 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,0103076 0,03371013 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0103076 0,03366506 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0103076 0,03362012 ! reflex GO:0060004 17 8 0,000 0,0103076 0,03357529 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0103076 0,03353058 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,0103076 0,03348599 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,0103076 0,03344152 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0103076 0,03339717 ! pigment granule organization GO:0048753 17 8 0,000 0,0103076 0,03335294 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0103076 0,03330882 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,0103076 0,03326482 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,0103076 0,03322093 ! astrocyte differentiation GO:0048708 19 8 0,000 0,0103076 0,03317716 ! histidine catabolic process GO:0006548 10 8 0,000 0,0103076 0,03313351 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0103076 0,03308997 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,0103076 0,03304654 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,0103076 0,03300323 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,0103076 0,03296003 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,0103076 0,03291695 ! melanin metabolic process GO:0006582 17 8 0,000 0,0103076 0,03287398 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,0103076 0,03283112 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,0103076 0,03278837 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,0103076 0,03274573 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0103076 0,0327032 ! macrophage activation GO:0042116 13 8 0,000 0,0103076 0,03266079 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0103076 0,03261848 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0103076 0,03257628 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,0103076 0,03253419 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0103076 0,03249221 ! purine salvage GO:0043101 12 8 0,000 0,0103076 0,03245034 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,0103076 0,03240858 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0103076 0,03236692 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,0103076 0,03232537 ! osteoblast development GO:0002076 17 8 0,000 0,0103076 0,03228393 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,0103076 0,03224259 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,0103076 0,03220136 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,0103076 0,03216024 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,0103076 0,03211922 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0103076 0,0320783 ! response to UV-B GO:0010224 17 8 0,000 0,0103076 0,03203749 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,0103076 0,03199678 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0103076 0,03195618 ! intermediate filament organization GO:0045109 12 8 0,000 0,0103076 0,03191567 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,0103076 0,03187527 ! cellular extravasation GO:0045123 13 8 0,000 0,0103076 0,03183498 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,0103076 0,03179478 ! response to antibiotic GO:0046677 11 8 0,000 0,0103076 0,03175469 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,0103076 0,03171469 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,0103076 0,0316748 ! DNA topological change GO:0006265 12 8 0,000 0,0103076 0,03163501 ! response to tropane GO:0014073 15 8 0,000 0,0103076 0,03159532 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,0103076 0,03155572 ! melanosome transport GO:0032402 13 8 0,000 0,0103076 0,03151623 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,0103076 0,03147683 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,0103076 0,03143754 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0103076 0,03139834 ! mast cell activation GO:0045576 14 8 0,000 0,0103076 0,03135924 ! multicellular organismal aging GO:0010259 20 8 0,000 0,0103076 0,03132023 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,0103076 0,03128132 ! gas homeostasis GO:0033483 14 8 0,000 0,0103076 0,03124251 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,0103076 0,0312038 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,0103076 0,03116518 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,0103076 0,03112666 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0103076 0,03108823 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0103076 0,0310499 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,0103076 0,03101166 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0103076 0,03097351 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,0103076 0,03093546 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,0103076 0,0308975 ! intracellular lipid transport GO:0032365 16 8 0,000 0,0103076 0,03085964 ! response to tumor cell GO:0002347 16 8 0,000 0,0103076 0,03082187 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0103076 0,03078419 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,0103076 0,0307466 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,0103076 0,03070911 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,0103076 0,0306717 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0103076 0,03063439 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,0103076 0,03059716 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,0103076 0,03056003 ! hormone catabolic process GO:0042447 17 8 0,000 0,0103076 0,03052299 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,0103076 0,03048604 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,0103076 0,03044917 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,0103076 0,0304124 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,0103076 0,03037571 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0103076 0,03033912 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,0103076 0,03030261 ! adult feeding behavior GO:0008343 10 8 0,000 0,0103076 0,03026619 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,0103076 0,03022985 ! ATP catabolic process GO:0006200 11 8 0,000 0,0103076 0,0301936 ! blastocyst growth GO:0001832 19 8 0,000 0,0103076 0,03015744 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0103076 0,03012137 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0103076 0,03008538 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,0103076 0,03004948 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0103076 0,03001367 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,0103076 0,02997794 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,0103076 0,02994229 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,0103076 0,02990673 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,0103076 0,02987125 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,0103076 0,02983586 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,0103076 0,02980055 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0103076 0,02976533 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,0103076 0,02973018 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,0103076 0,02969513 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0103076 0,02966015 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,0103076 0,02962525 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,0103076 0,02959044 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0103076 0,02955571 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,0103076 0,02952106 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,0103076 0,02948649 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,0103076 0,02945201 ! axon extension GO:0048675 16 9 0,000 0,01158872 0,03307388 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01158872 0,03303529 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01158872 0,03299678 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01158872 0,03295837 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01158872 0,03292005 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01158872 0,03288181 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01158872 0,03284367 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01158872 0,03280561 ! reproductive behavior GO:0019098 22 9 0,000 0,01158872 0,03276764 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01158872 0,03272976 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01158872 0,03269196 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01158872 0,03265426 ! UTP metabolic process GO:0046051 10 9 0,000 0,01158872 0,03261664 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01158872 0,0325791 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01158872 0,03254166 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01158872 0,03250429 ! artery development GO:0060840 25 9 0,000 0,01158872 0,03246702 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01158872 0,03242983 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01158872 0,03239272 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01158872 0,0323557 ! equilibrioception GO:0050957 20 9 0,000 0,01158872 0,03231877 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01158872 0,03228192 ! chemosensory behavior GO:0007635 21 9 0,000 0,01158872 0,03224515 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01158872 0,03220846 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01158872 0,03217186 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01158872 0,03213535 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01158872 0,03209891 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01158872 0,03206256 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01158872 0,03202629 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01158872 0,0319901 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01158872 0,031954 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01158872 0,03191797 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01158872 0,03188203 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01158872 0,03184616 ! protein targeting to ER GO:0045047 25 9 0,000 0,01158872 0,03181038 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01158872 0,03177468 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01158872 0,03173906 ! T cell selection GO:0045058 27 9 0,000 0,01158872 0,03170352 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01158872 0,03166805 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01158872 0,03163267 ! glycine catabolic process GO:0006546 15 9 0,000 0,01158872 0,03159737 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01158872 0,03156214 ! endosome organization GO:0007032 20 9 0,000 0,01158872 0,03152699 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01158872 0,03149193 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01158872 0,03145693 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01158872 0,03142202 ! mannose metabolic process GO:0006013 13 9 0,000 0,01158872 0,03138718 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01158872 0,03135243 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01158872 0,03131774 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01158872 0,03128314 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01158872 0,03124861 ! receptor clustering GO:0043113 20 9 0,000 0,01158872 0,03121416 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01158872 0,03117978 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01158872 0,03114548 ! retinol metabolic process GO:0042572 20 9 0,000 0,01158872 0,03111125 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01158872 0,0310771 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01158872 0,03104303 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01158872 0,03100903 ! macrophage differentiation GO:0030225 15 9 0,000 0,01158872 0,0309751 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01158872 0,03094125 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01158872 0,03090747 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01158872 0,03087376 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01158872 0,03084013 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01158872 0,03080657 ! response to amine stimulus GO:0014075 13 9 0,000 0,01158872 0,03077309 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01158872 0,03073967 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01158872 0,03070633 ! erythrocyte development GO:0048821 17 9 0,000 0,01158872 0,03067307 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01158872 0,03063987 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01158872 0,03060675 ! renal water homeostasis GO:0003091 15 9 0,000 0,01158872 0,03057369 ! postreplication repair GO:0006301 25 9 0,000 0,01158872 0,03054071 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01158872 0,0305078 ! icosanoid secretion GO:0032309 15 9 0,000 0,01158872 0,03047496 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01158872 0,03044219 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01158872 0,0304095 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01158872 0,03037687 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01158872 0,03034431 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01158872 0,03031182 ! sterol catabolic process GO:0016127 14 9 0,000 0,01158872 0,0302794 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01158872 0,03024705 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01158872 0,03021477 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01158872 0,03018256 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01158872 0,03015042 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01158872 0,03011834 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01158872 0,03008633 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01158872 0,0300544 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01158872 0,03002252 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01158872 0,02999072 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01158872 0,02995898 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01158872 0,02992732 ! purine base metabolic process GO:0006144 25 9 0,000 0,01158872 0,02989571 ! pigment granule transport GO:0051904 17 9 0,000 0,01158872 0,02986418 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01158872 0,02983271 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01158872 0,02980131 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01158872 0,02976997 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01158872 0,0297387 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01158872 0,02970749 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01158872 0,02967635 ! mitochondrion localization GO:0051646 18 9 0,000 0,01158872 0,02964528 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01286822 0,03288394 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01286822 0,03284958 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01286822 0,03281529 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01286822 0,03278108 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01286822 0,03274693 ! associative learning GO:0008306 21 10 0,000 0,01286822 0,03271285 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,01286822 0,03267885 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01286822 0,03264491 ! phosphate transport GO:0006817 24 10 0,000 0,01286822 0,03261105 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01286822 0,03257726 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01286822 0,03254353 ! CTP metabolic process GO:0046036 11 10 0,000 0,01286822 0,03250988 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01286822 0,03247629 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01286822 0,03244278 ! GTP metabolic process GO:0046039 11 10 0,000 0,01286822 0,03240933 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01286822 0,03237595 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01286822 0,03234265 ! social behavior GO:0035176 29 10 0,000 0,01286822 0,03230941 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01286822 0,03227623 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01286822 0,03224313 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01286822 0,03221009 ! androgen metabolic process GO:0008209 17 10 0,000 0,01286822 0,03217713 ! phospholipid efflux GO:0033700 19 10 0,000 0,01286822 0,03214422 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01286822 0,03211139 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01286822 0,03207862 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01286822 0,03204592 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01286822 0,03201329 ! lung alveolus development GO:0048286 26 10 0,000 0,01286822 0,03198072 ! pathogenesis GO:0009405 17 10 0,000 0,01286822 0,03194822 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01286822 0,03191579 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01286822 0,03188342 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01286822 0,03185112 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01286822 0,03181888 ! endoderm development GO:0007492 18 10 0,000 0,01286822 0,03178671 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01286822 0,0317546 ! arginine catabolic process GO:0006527 17 10 0,000 0,01286822 0,03172255 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01286822 0,03169058 ! proline metabolic process GO:0006560 13 10 0,000 0,01286822 0,03165866 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01286822 0,03162681 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01286822 0,03159503 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01286822 0,0315633 ! V(D)J recombination GO:0033151 34 10 0,000 0,01286822 0,03153165 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01286822 0,03150005 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01286822 0,03146852 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01286822 0,03143705 ! B cell proliferation GO:0042100 19 10 0,000 0,01286822 0,03140565 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01286822 0,0313743 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01286822 0,03134302 ! multicellular organism growth GO:0035264 19 10 0,000 0,01286822 0,0313118 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01286822 0,03128065 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01286822 0,03124955 ! ruffle organization GO:0031529 17 10 0,000 0,01286822 0,03121852 ! epithelial cell development GO:0002064 21 10 0,000 0,01286822 0,03118755 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01286822 0,03115664 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01286822 0,03112579 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01286822 0,03109501 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01286822 0,03106428 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01286822 0,03103361 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01286822 0,03100301 ! motor axon guidance GO:0008045 22 10 0,000 0,01286822 0,03097246 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01286822 0,03094198 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01286822 0,03091155 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01286822 0,03088119 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01286822 0,03085088 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01286822 0,03082064 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01286822 0,03079045 ! segment specification GO:0007379 15 10 0,000 0,01286822 0,03076032 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01286822 0,03073026 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01286822 0,03070025 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01286822 0,03067029 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01286822 0,0306404 ! response to dsRNA GO:0043331 23 10 0,000 0,01286822 0,03061057 ! DNA ligation GO:0006266 18 10 0,000 0,01286822 0,03058079 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01286822 0,03055107 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01286822 0,03052141 ! melanosome localization GO:0032400 16 10 0,000 0,01286822 0,03049181 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01286822 0,03046226 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01286822 0,03043277 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01286822 0,03040334 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01286822 0,03037396 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01286822 0,03034464 ! induction of an organ GO:0001759 17 10 0,000 0,01286822 0,03031538 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01286822 0,03028618 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01286822 0,03025703 ! protein sumoylation GO:0016925 17 10 0,000 0,01286822 0,03022793 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01286822 0,0301989 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01286822 0,03016991 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01286822 0,03014099 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01286822 0,03011212 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01286822 0,0300833 ! salivary gland development GO:0007431 28 10 0,000 0,01286822 0,03005454 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01286822 0,03002584 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01286822 0,02999719 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01286822 0,02996859 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01286822 0,02994005 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01286822 0,02991156 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01286822 0,02988313 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01286822 0,02985475 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01286822 0,02982642 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01286822 0,02979815 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01286822 0,02976993 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01286822 0,02974177 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01286822 0,02971366 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01286822 0,0296856 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01286822 0,0296576 ! blastocyst formation GO:0001825 18 10 0,000 0,01286822 0,02962964 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01286822 0,02960174 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01286822 0,0295739 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01286822 0,0295461 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01286822 0,02951836 ! response to nicotine GO:0035094 20 10 0,000 0,01286822 0,02949067 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01286822 0,02946303 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01286822 0,02943544 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01414609 0,03232825 ! respiratory burst GO:0045730 17 11 0,000 0,01414609 0,03229804 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01414609 0,03226788 ! neuron fate specification GO:0048665 18 11 0,000 0,01414609 0,03223778 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01414609 0,03220774 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01414609 0,03217775 ! thyroid gland development GO:0030878 26 11 0,000 0,01414609 0,03214782 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,01414609 0,03211794 ! synapsis GO:0007129 14 11 0,000 0,01414609 0,03208812 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01414609 0,03205835 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01414609 0,03202864 ! response to pain GO:0048265 27 11 0,000 0,01414609 0,03199898 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01414609 0,03196938 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01414609 0,03193984 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01414609 0,03191034 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01414609 0,03188091 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01414609 0,03185152 ! bone resorption GO:0045453 16 11 0,000 0,01414609 0,03182219 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01414609 0,03179292 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01414609 0,0317637 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01414609 0,03173453 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01414609 0,03170542 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01414609 0,03167636 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01414609 0,03164735 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01414609 0,03161839 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01414609 0,03158949 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01414609 0,03156064 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01414609 0,03153185 ! UV protection GO:0009650 20 11 0,000 0,01414609 0,0315031 ! adult heart development GO:0007512 16 11 0,000 0,01414609 0,03147441 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01414609 0,03144577 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01414609 0,03141719 ! macroautophagy GO:0016236 19 11 0,000 0,01414609 0,03138865 ! temperature homeostasis GO:0001659 18 11 0,000 0,01414609 0,03136017 ! behavioral fear response GO:0001662 27 11 0,000 0,01414609 0,03133173 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01414609 0,03130335 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01414609 0,03127503 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01414609 0,03124675 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01414609 0,03121852 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01414609 0,03119035 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01414609 0,03116222 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01414609 0,03113415 ! regulation of organ growth GO:0046620 14 11 0,000 0,01414609 0,03110612 ! pigment granule localization GO:0051875 20 11 0,000 0,01414609 0,03107815 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01414609 0,03105023 ! vasoconstriction GO:0042310 20 11 0,000 0,01414609 0,03102236 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01414609 0,03099453 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01414609 0,03096676 ! embryonic axis specification GO:0000578 19 11 0,000 0,01414609 0,03093904 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01414609 0,03091136 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01414609 0,03088374 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01414609 0,03085616 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01414609 0,03082864 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01414609 0,03080116 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01414609 0,03077373 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01414609 0,03074636 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01414609 0,03071903 ! prophase GO:0051324 17 11 0,000 0,01414609 0,03069174 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01414609 0,03066451 ! nucleosome positioning GO:0016584 15 11 0,000 0,01414609 0,03063733 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01414609 0,03061019 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01414609 0,0305831 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01414609 0,03055606 ! apical protein localization GO:0045176 18 11 0,000 0,01414609 0,03052907 ! acid secretion GO:0046717 20 11 0,000 0,01414609 0,03050212 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01414609 0,03047522 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01414609 0,03044837 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,01414609 0,03042157 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01414609 0,03039481 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01414609 0,03036811 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01414609 0,03034144 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01414609 0,03031483 ! cholesterol efflux GO:0033344 21 11 0,000 0,01414609 0,03028826 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01414609 0,03026174 ! oocyte development GO:0048599 20 11 0,000 0,01414609 0,03023526 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01414609 0,03020883 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01414609 0,03018245 ! embryonic gut development GO:0048566 19 11 0,000 0,01414609 0,03015611 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01414609 0,03012982 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01414609 0,03010357 ! activation of innate immune response GO:0002218 16 11 0,000 0,01414609 0,03007737 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01414609 0,03005122 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01414609 0,03002511 ! lysogeny GO:0030069 22 11 0,000 0,01414609 0,02999905 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01414609 0,02997303 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01414609 0,02994706 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01414609 0,02992113 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01414609 0,02989525 ! nucleus localization GO:0051647 22 11 0,000 0,01414609 0,02986941 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01542235 0,0325361 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01542235 0,03250803 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01542235 0,03248 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01542235 0,03245203 ! virus-host interaction GO:0019048 30 12 0,000 0,01542235 0,0324241 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,01542235 0,03239622 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01542235 0,03236839 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01542235 0,0323406 ! protein complex disassembly GO:0043241 28 12 0,000 0,01542235 0,03231287 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01542235 0,03228518 ! hippocampus development GO:0021766 29 12 0,000 0,01542235 0,03225754 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01542235 0,03222994 ! T cell proliferation GO:0042098 32 12 0,000 0,01542235 0,03220239 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01542235 0,0321749 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01542235 0,03214744 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01542235 0,03212004 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01542235 0,03209268 ! drug transport GO:0015893 16 12 0,000 0,01542235 0,03206536 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01542235 0,0320381 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01542235 0,03201088 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01542235 0,0319837 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01542235 0,03195658 ! focal adhesion formation GO:0048041 37 12 0,000 0,01542235 0,03192949 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01542235 0,03190246 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01542235 0,03187547 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01542235 0,03184852 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01542235 0,03182162 ! lipid digestion GO:0044241 21 12 0,000 0,01542235 0,03179477 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01542235 0,03176796 ! entry into host cell GO:0030260 34 12 0,000 0,01542235 0,0317412 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01542235 0,03171448 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01542235 0,03168781 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01542235 0,03166118 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01542235 0,03163459 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01542235 0,03160806 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01542235 0,03158156 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01542235 0,03155511 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01542235 0,0315287 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01542235 0,03150234 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01542235 0,03147603 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01542235 0,03144975 ! cranial nerve development GO:0021545 23 12 0,000 0,01542235 0,03142352 ! fucose catabolic process GO:0019317 25 12 0,000 0,01542235 0,03139734 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01542235 0,03137119 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01542235 0,03134509 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01542235 0,03131904 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01542235 0,03129303 ! zymogen activation GO:0031638 18 12 0,000 0,01542235 0,03126706 ! T cell homeostasis GO:0043029 28 12 0,000 0,01542235 0,03124113 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01542235 0,03121525 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01542235 0,03118941 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,01542235 0,03116361 ! oocyte differentiation GO:0009994 21 12 0,000 0,01542235 0,03113785 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01542235 0,03111214 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01542235 0,03108647 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01542235 0,03106084 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01542235 0,03103526 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01542235 0,03100971 ! defense response to fungus GO:0050832 15 12 0,000 0,01542235 0,03098421 ! developmental induction GO:0031128 22 12 0,000 0,01542235 0,03095875 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,01542235 0,03093334 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01542235 0,03090796 ! response to cold GO:0009409 17 12 0,000 0,01542235 0,03088262 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01542235 0,03085733 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01542235 0,03083208 ! localization within membrane GO:0051668 26 12 0,000 0,01542235 0,03080687 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01669699 0,03332578 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01669699 0,03329857 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01669699 0,03327141 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01669699 0,0332443 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01669699 0,03321722 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01669699 0,0331902 ! peroxisomal transport GO:0043574 28 13 0,000 0,01669699 0,03316321 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01669699 0,03313627 ! cartilage condensation GO:0001502 22 13 0,000 0,01669699 0,03310938 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01669699 0,03308252 ! organelle fusion GO:0048284 36 13 0,000 0,01669699 0,03305571 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01669699 0,03302895 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01669699 0,03300223 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01669699 0,03297555 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01669699 0,03294891 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01669699 0,03292232 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01669699 0,03289577 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01669699 0,03286926 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01669699 0,0328428 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01669699 0,03281637 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01669699 0,03278999 ! methionine metabolic process GO:0006555 31 13 0,000 0,01669699 0,03276366 ! plasma membrane organization GO:0007009 27 13 0,000 0,01669699 0,03273736 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01669699 0,03271111 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01669699 0,0326849 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01669699 0,03265873 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01669699 0,0326326 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01669699 0,03260652 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01669699 0,03258047 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01669699 0,03255447 ! exocrine system development GO:0035272 34 13 0,000 0,01669699 0,03252851 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01669699 0,03250259 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01669699 0,03247671 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01669699 0,03245088 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01669699 0,03242508 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01669699 0,03239933 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01669699 0,03237361 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01669699 0,03234794 ! protein homotetramerization GO:0051289 24 13 0,000 0,01669699 0,03232231 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01669699 0,03229672 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01669699 0,03227116 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01669699 0,03224565 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01669699 0,03222018 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01669699 0,03219475 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,01669699 0,03216936 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01669699 0,03214401 ! histone methylation GO:0016571 29 13 0,000 0,01669699 0,0321187 ! chromatin silencing GO:0006342 29 13 0,000 0,01669699 0,03209343 ! gland morphogenesis GO:0022612 31 13 0,000 0,01669699 0,0320682 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01669699 0,03204301 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,01669699 0,03201786 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01669699 0,03199275 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01669699 0,03196767 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01669699 0,03194264 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01669699 0,03191765 ! spleen development GO:0048536 24 13 0,000 0,01669699 0,03189269 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01669699 0,03186777 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01669699 0,0318429 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01669699 0,03181806 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01669699 0,03179326 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01669699 0,0317685 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01669699 0,03174378 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01669699 0,03171909 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01669699 0,03169445 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01669699 0,03166984 ! insulin secretion GO:0030073 24 13 0,000 0,01669699 0,03164527 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01669699 0,03162074 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01669699 0,03159624 ! acrosome reaction GO:0007340 19 13 0,000 0,01669699 0,03157179 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01669699 0,03154737 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01669699 0,03152299 ! rRNA transcription GO:0009303 28 14 0,000 0,01797002 0,0339002 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01797002 0,03387404 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01797002 0,03384792 ! water transport GO:0006833 21 14 0,000 0,01797002 0,03382185 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01797002 0,03379581 ! non-recombinational repair GO:0000726 29 14 0,000 0,01797002 0,03376981 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01797002 0,03374386 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01797002 0,03371794 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01797002 0,03369206 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01797002 0,03366623 ! lipid localization GO:0010876 32 14 0,000 0,01797002 0,03364043 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,01797002 0,03361467 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01797002 0,03358895 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01797002 0,03356327 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01797002 0,03353763 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01797002 0,03351203 ! arginine metabolic process GO:0006525 21 14 0,000 0,01797002 0,03348647 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01797002 0,03346094 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01797002 0,03343546 ! regulation of heart rate GO:0002027 25 14 0,000 0,01797002 0,03341001 ! fear response GO:0042596 34 14 0,000 0,01797002 0,03338461 ! organic alcohol transport GO:0015850 29 14 0,000 0,01797002 0,03335924 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01797002 0,03333391 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01797002 0,03330862 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01797002 0,03328336 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01797002 0,03325815 ! bone mineralization GO:0030282 18 14 0,000 0,01797002 0,03323297 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01797002 0,03320784 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01797002 0,03318273 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01797002 0,03315767 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01797002 0,03313265 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01797002 0,03310766 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01797002 0,03308271 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01797002 0,0330578 ! ribosome assembly GO:0042255 18 14 0,000 0,01797002 0,03303293 ! cerebellum development GO:0021549 23 14 0,000 0,01797002 0,03300809 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01797002 0,03298329 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01797002 0,03295853 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01797002 0,0329338 ! response to gamma radiation GO:0010332 30 14 0,000 0,01797002 0,03290911 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01797002 0,03288446 ! NADP metabolic process GO:0006739 24 14 0,000 0,01797002 0,03285985 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01797002 0,03283527 ! oxygen transport GO:0015671 22 14 0,000 0,01797002 0,03281073 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01797002 0,03278623 ! male genitalia development GO:0030539 26 14 0,000 0,01797002 0,03276176 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01797002 0,03273733 ! regulation of axon extension GO:0030516 43 14 0,000 0,01797002 0,03271293 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01797002 0,03268858 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01797002 0,03266425 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,01797002 0,03263997 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01924143 0,03492335 ! lactation GO:0007595 30 15 0,000 0,01924143 0,03489742 ! reproductive cellular process GO:0048610 22 15 0,000 0,01924143 0,03487153 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01924143 0,03484568 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,01924143 0,03481987 ! superoxide anion generation GO:0042554 22 15 0,000 0,01924143 0,0347941 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,01924143 0,03476836 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,01924143 0,03474266 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,01924143 0,03471701 ! copper ion transport GO:0006825 22 15 0,000 0,01924143 0,03469138 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,01924143 0,0346658 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,01924143 0,03464025 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,01924143 0,03461475 ! sulfate transport GO:0008272 27 15 0,000 0,01924143 0,03458928 ! response to cAMP GO:0051591 25 15 0,000 0,01924143 0,03456384 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,01924143 0,03453845 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,01924143 0,03451309 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,01924143 0,03448777 ! response to hexose stimulus GO:0009746 25 15 0,000 0,01924143 0,03446248 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,01924143 0,03443723 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,01924143 0,03441202 ! vesicle coating GO:0006901 38 15 0,000 0,01924143 0,03438685 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,01924143 0,03436171 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,01924143 0,03433661 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,01924143 0,03431155 ! regulation of exocytosis GO:0017157 26 15 0,000 0,01924143 0,03428652 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,01924143 0,03426153 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,01924143 0,03423658 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,01924143 0,03421166 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,01924143 0,03418678 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,01924143 0,03416194 ! regulation of vasodilation GO:0042312 27 15 0,000 0,01924143 0,03413713 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,01924143 0,03411235 ! histone deacetylation GO:0016575 24 15 0,000 0,01924143 0,03408762 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,01924143 0,03406292 ! water homeostasis GO:0030104 28 15 0,000 0,01924143 0,03403825 ! cofactor transport GO:0051181 30 15 0,000 0,01924143 0,03401362 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01924143 0,03398903 ! muscle maintenance GO:0046716 26 15 0,000 0,01924143 0,03396447 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,01924143 0,03393995 ! intestinal absorption GO:0050892 31 15 0,000 0,01924143 0,03391546 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01924143 0,03389101 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,01924143 0,03386659 ! heme biosynthetic process GO:0006783 33 15 0,000 0,01924143 0,03384221 ! cell killing GO:0001906 32 15 0,000 0,01924143 0,03381786 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,01924143 0,03379355 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,01924143 0,03376927 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,01924143 0,03374503 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,01924143 0,03372082 ! actin filament polymerization GO:0030041 27 15 0,000 0,01924143 0,03369665 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,01924143 0,03367251 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02051124 0,03586898 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02051124 0,03584332 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02051124 0,0358177 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02051124 0,03579211 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02051124 0,03576657 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02051124 0,03574105 ! bone remodeling GO:0046849 28 16 0,000 0,02051124 0,03571558 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02051124 0,03569014 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,02051124 0,03566474 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02051124 0,03563937 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02051124 0,03561404 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02051124 0,03558875 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02051124 0,03556349 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02051124 0,03553827 ! startle response GO:0001964 28 16 0,000 0,02051124 0,03551308 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02051124 0,03548793 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02051124 0,03546282 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02051124 0,03543774 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02051124 0,03541269 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02051124 0,03538768 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02051124 0,03536271 ! pituitary gland development GO:0021983 30 16 0,000 0,02051124 0,03533777 ! response to osmotic stress GO:0006970 27 16 0,000 0,02051124 0,03531287 ! lysosomal transport GO:0007041 31 16 0,000 0,02051124 0,035288 ! fructose metabolic process GO:0006000 25 16 0,000 0,02051124 0,03526317 ! L-amino acid transport GO:0015807 33 16 0,000 0,02051124 0,03523837 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02051124 0,0352136 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02051124 0,03518888 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02051124 0,03516418 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02051124 0,03513952 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02051124 0,0351149 ! axon cargo transport GO:0008088 46 16 0,000 0,02051124 0,03509031 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02051124 0,03506575 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02051124 0,03504123 ! DNA replication initiation GO:0006270 28 16 0,000 0,02051124 0,03501674 ! neuron recognition GO:0008038 40 16 0,000 0,02051124 0,03499229 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02051124 0,03496787 ! tissue regeneration GO:0042246 27 16 0,000 0,02051124 0,03494349 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02051124 0,03491913 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02051124 0,03489482 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02051124 0,03487053 ! biomineral formation GO:0031214 22 16 0,000 0,02051124 0,03484629 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02051124 0,03482207 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02051124 0,03479789 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02051124 0,03477374 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02051124 0,03474962 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02051124 0,03472554 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02051124 0,03470149 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02051124 0,03467748 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02051124 0,0346535 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02051124 0,03462955 ! peptide hormone processing GO:0016486 27 16 0,000 0,02051124 0,03460563 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02177944 0,03671992 ! metencephalon development GO:0022037 32 17 0,000 0,02177944 0,03669459 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02177944 0,03666931 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02177944 0,03664405 ! signal complex assembly GO:0007172 47 17 0,000 0,02177944 0,03661883 ! filopodium assembly GO:0046847 42 17 0,000 0,02177944 0,03659365 ! endothelial cell migration GO:0043542 31 17 0,000 0,02177944 0,0365685 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02177944 0,03654338 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02177944 0,0365183 ! glial cell development GO:0021782 28 17 0,000 0,02177944 0,03649325 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02177944 0,03646824 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02177944 0,03644326 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02177944 0,03641832 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,02177944 0,03639341 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02177944 0,03636853 ! myoblast differentiation GO:0045445 50 17 0,000 0,02177944 0,03634369 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02177944 0,03631888 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02177944 0,03629411 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02177944 0,03626937 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02177944 0,03624466 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02177944 0,03621999 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02177944 0,03619535 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02177944 0,03617074 ! NAD metabolic process GO:0019674 33 17 0,000 0,02177944 0,03614617 ! membrane budding GO:0006900 42 17 0,000 0,02177944 0,03612163 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02177944 0,03609712 ! regulation of protein binding GO:0043393 33 17 0,000 0,02177944 0,03607265 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02177944 0,03604821 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02177944 0,03602381 ! genitalia development GO:0048806 32 17 0,000 0,02177944 0,03599943 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02177944 0,03597509 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02177944 0,03595079 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02177944 0,03592651 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02177944 0,03590227 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02177944 0,03587806 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02177944 0,03585388 ! steroid catabolic process GO:0006706 34 17 0,000 0,02177944 0,03582974 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02177944 0,03580563 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02177944 0,03578155 ! gas transport GO:0015669 26 17 0,000 0,02177944 0,0357575 ! organic cation transport GO:0015695 32 17 0,000 0,02177944 0,03573349 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02177944 0,0357095 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02177944 0,03568555 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02177944 0,03566164 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,02304603 0,03771028 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02304603 0,03768503 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02304603 0,03765983 ! limbic system development GO:0021761 40 18 0,000 0,02304603 0,03763465 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02304603 0,03760951 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02304603 0,03758441 ! adult walking behavior GO:0007628 36 18 0,000 0,02304603 0,03755933 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02304603 0,03753429 ! heart looping GO:0001947 34 18 0,000 0,02304603 0,03750929 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02304603 0,03748432 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02304603 0,03745938 ! centrosome cycle GO:0007098 26 18 0,000 0,02304603 0,03743447 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02304603 0,0374096 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02304603 0,03738476 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02304603 0,03735995 ! glycine metabolic process GO:0006544 30 18 0,000 0,02304603 0,03733517 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02304603 0,03731043 ! response to retinoic acid GO:0032526 31 18 0,000 0,02304603 0,03728572 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02304603 0,03726105 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,02304603 0,0372364 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02304603 0,03721179 ! DNA integration GO:0015074 32 18 0,000 0,02304603 0,03718721 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02304603 0,03716267 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02304603 0,03713815 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02304603 0,03711367 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02304603 0,03708922 ! neural crest cell migration GO:0001755 41 18 0,000 0,02304603 0,03706481 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02304603 0,03704042 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02304603 0,03701607 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02304603 0,03699175 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02304603 0,03696746 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02304603 0,0369432 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02304603 0,03691898 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02304603 0,03689478 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02304603 0,03687062 ! detection of bacterium GO:0016045 22 18 0,000 0,02304603 0,03684649 ! nerve development GO:0021675 34 18 0,000 0,02304603 0,03682239 ! defense response to virus GO:0051607 43 18 0,000 0,02304603 0,03679833 ! microspike assembly GO:0030035 46 18 0,000 0,02304603 0,03677429 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02304603 0,03675029 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02431101 0,03874221 ! positive regulation of translation GO:0045727 31 19 0,000 0,02431101 0,03871695 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02431101 0,03869173 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,02431101 0,03866654 ! neuron maturation GO:0042551 46 19 0,000 0,02431101 0,03864138 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02431101 0,03861626 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02431101 0,03859116 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02431101 0,03856611 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02431101 0,03854108 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02431101 0,03851608 ! inositol metabolic process GO:0006020 33 19 0,000 0,02431101 0,03849112 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02431101 0,03846619 ! memory GO:0007613 34 19 0,000 0,02431101 0,0384413 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02431101 0,03841643 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02431101 0,0383916 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02431101 0,0383668 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02431101 0,03834203 ! cerebral cortex development GO:0021987 40 19 0,000 0,02431101 0,03831729 ! pigmentation during development GO:0048066 42 19 0,000 0,02431101 0,03829259 ! response to vitamin A GO:0033189 32 19 0,000 0,02431101 0,03826791 ! heme metabolic process GO:0042168 40 19 0,000 0,02431101 0,03824327 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02431101 0,03821866 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02431101 0,03819408 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02431101 0,03816954 ! response to fungus GO:0009620 26 19 0,000 0,02431101 0,03814502 ! peptide cross-linking GO:0018149 39 19 0,000 0,02431101 0,03812054 ! protein export from nucleus GO:0006611 40 19 0,000 0,02431101 0,03809609 ! heart process GO:0003015 32 19 0,000 0,02431101 0,03807167 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02431101 0,03804728 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02431101 0,03802292 ! visual learning GO:0008542 38 19 0,000 0,02431101 0,03799859 ! cellular pigmentation GO:0033059 37 19 0,000 0,02431101 0,0379743 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02431101 0,03795003 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02431101 0,0379258 ! vitamin transport GO:0051180 31 19 0,000 0,02431101 0,0379016 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02431101 0,03787742 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02431101 0,03785328 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02431101 0,03782917 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02431101 0,03780509 ! cilium assembly GO:0042384 38 19 0,000 0,02431101 0,03778104 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02431101 0,03775703 ! protein secretion GO:0009306 45 20 0,000 0,0255744 0,03969393 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0255744 0,03966873 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0255744 0,03964356 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0255744 0,03961842 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,0255744 0,03959331 ! skin development GO:0043588 42 20 0,000 0,0255744 0,03956824 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,0255744 0,03954319 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0255744 0,03951818 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0255744 0,0394932 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0255744 0,03946825 ! response to vitamin GO:0033273 36 20 0,000 0,0255744 0,03944334 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0255744 0,03941845 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,0255744 0,0393936 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0255744 0,03936878 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0255744 0,03934398 ! response to alkaloid GO:0043279 38 20 0,000 0,0255744 0,03931922 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0255744 0,0392945 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,0255744 0,0392698 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,0255744 0,03924513 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,0255744 0,03922049 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,0255744 0,03919589 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,0255744 0,03917131 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,0255744 0,03914677 ! body fluid secretion GO:0007589 33 20 0,000 0,0255744 0,03912226 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0255744 0,03909778 ! peptide secretion GO:0002790 38 20 0,000 0,0255744 0,03907333 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0255744 0,0390489 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,0255744 0,03902451 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0255744 0,03900015 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0255744 0,03897582 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0255744 0,03895153 ! cell-cell junction organization GO:0045216 43 20 0,000 0,0255744 0,03892726 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,0255744 0,03890302 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,0255744 0,03887881 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0255744 0,03885463 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0255744 0,03883048 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0255744 0,03880636 ! regulation of glucose import GO:0046324 30 20 0,000 0,0255744 0,03878228 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0255744 0,03875822 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,0255744 0,03873419 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0255744 0,03871019 ! negative regulation of translation GO:0017148 32 20 0,000 0,0255744 0,03868622 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,0255744 0,03866228 ! regulation of cell killing GO:0031341 46 21 0,000 0,02683618 0,0405447 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02683618 0,04051964 ! hormone secretion GO:0046879 39 21 0,000 0,02683618 0,04049462 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02683618 0,04046962 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02683618 0,04044465 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02683618 0,04041972 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02683618 0,04039481 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02683618 0,04036994 ! ovarian follicle development GO:0001541 39 21 0,000 0,02683618 0,0403451 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02683618 0,04032028 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,02683618 0,0402955 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02683618 0,04027075 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02683618 0,04024603 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02683618 0,04022134 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02683618 0,04019668 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02683618 0,04017205 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02683618 0,04014745 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,02683618 0,04012288 ! sensory perception of pain GO:0019233 33 21 0,000 0,02683618 0,04009834 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02683618 0,04007383 ! diencephalon development GO:0021536 36 21 0,000 0,02683618 0,04004935 ! collagen fibril organization GO:0030199 62 21 0,000 0,02683618 0,0400249 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02683618 0,04000048 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02683618 0,03997609 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02683618 0,03995173 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02683618 0,0399274 ! collagen catabolic process GO:0030574 29 21 0,000 0,02683618 0,03990309 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02683618 0,03987882 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02683618 0,03985458 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02683618 0,03983037 ! actin filament-based movement GO:0030048 47 21 0,000 0,02683618 0,03980618 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02683618 0,03978203 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,02809636 0,04162487 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,02809636 0,04159964 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,02809636 0,04157445 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,02809636 0,04154928 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,02809636 0,04152415 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,02809636 0,04149904 ! microtubule-based transport GO:0010970 59 22 0,000 0,02809636 0,04147397 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,02809636 0,04144892 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,02809636 0,04142391 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,02809636 0,04139892 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,02809636 0,04137397 ! cellular response to starvation GO:0009267 37 22 0,000 0,02809636 0,04134904 ! vacuolar transport GO:0007034 41 22 0,000 0,02809636 0,04132415 ! central nervous system neuron development GO:0021954 47 22 0,000 0,02809636 0,04129929 ! fucose metabolic process GO:0006004 44 22 0,000 0,02809636 0,04127445 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,02809636 0,04124965 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,02809636 0,04122487 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,02809636 0,04120013 ! ureteric bud development GO:0001657 50 22 0,000 0,02809636 0,04117541 ! cell aging GO:0007569 48 22 0,000 0,02809636 0,04115073 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,02809636 0,04112607 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,02809636 0,04110145 ! cytolysis GO:0019835 27 22 0,000 0,02809636 0,04107685 ! renal system process GO:0003014 42 22 0,000 0,02809636 0,04105228 ! vasodilation GO:0042311 40 22 0,000 0,02809636 0,04102774 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,02809636 0,04100323 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,02809636 0,04097875 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,02809636 0,0409543 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,02809636 0,04092988 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,02809636 0,04090549 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,02809636 0,04088113 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,02809636 0,04085679 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,02809636 0,04083249 ! sarcomere organization GO:0045214 32 22 0,000 0,02809636 0,04080821 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,02809636 0,04078397 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,02809636 0,04075975 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,02809636 0,04073556 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,02809636 0,0407114 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,02809636 0,04068726 ! gut development GO:0048565 44 22 0,000 0,02809636 0,04066316 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,02809636 0,04063908 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,02809636 0,04061504 ! protein stabilization GO:0050821 41 22 0,000 0,02809636 0,04059102 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,02935495 0,04238425 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,02935495 0,04235921 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,02935495 0,04233421 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,02935495 0,04230923 ! gluconeogenesis GO:0006094 38 23 0,000 0,02935495 0,04228428 ! glycerol metabolic process GO:0006071 40 23 0,000 0,02935495 0,04225937 ! viral genome replication GO:0019079 44 23 0,000 0,02935495 0,04223448 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,02935495 0,04220962 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,02935495 0,04218479 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,02935495 0,04215999 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,02935495 0,04213522 ! regeneration GO:0031099 42 23 0,000 0,02935495 0,04211048 ! visual behavior GO:0007632 46 23 0,000 0,02935495 0,04208577 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,02935495 0,04206108 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,02935495 0,04203643 ! response to ethanol GO:0045471 47 23 0,000 0,02935495 0,0420118 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,02935495 0,0419872 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,02935495 0,04196264 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,02935495 0,0419381 ! peroxisome organization GO:0007031 43 23 0,000 0,02935495 0,04191359 ! lysosome organization GO:0007040 47 23 0,000 0,02935495 0,0418891 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,02935495 0,04186465 ! vesicle targeting GO:0006903 49 23 0,000 0,02935495 0,04184022 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,02935495 0,04181583 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,02935495 0,04179146 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,02935495 0,04176712 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,02935495 0,04174281 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,02935495 0,04171853 ! DNA modification GO:0006304 36 23 0,000 0,02935495 0,04169427 ! fatty acid transport GO:0015908 47 23 0,000 0,02935495 0,04167004 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,02935495 0,04164584 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,02935495 0,04162167 ! hormone transport GO:0009914 41 23 0,000 0,02935495 0,04159753 ! cell-cell recognition GO:0009988 28 23 0,000 0,02935495 0,04157342 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,02935495 0,04154933 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,02935495 0,04152527 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,02935495 0,04150124 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03061194 0,04325331 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03061194 0,04322831 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,03061194 0,04320334 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,03061194 0,0431784 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03061194 0,04315348 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03061194 0,04312859 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03061194 0,04310374 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03061194 0,04307891 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03061194 0,0430541 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03061194 0,04302933 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03061194 0,04300459 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,03061194 0,04297987 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03061194 0,04295519 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03061194 0,04293053 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03061194 0,0429059 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,03061194 0,0428813 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03061194 0,04285672 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03061194 0,04283218 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,03061194 0,04280766 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03061194 0,04278317 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03061194 0,04275871 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,03061194 0,04273427 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03061194 0,04270987 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03061194 0,04268549 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03061194 0,04266114 ! membrane depolarization GO:0051899 45 24 0,000 0,03061194 0,04263682 ! pallium development GO:0021543 56 24 0,000 0,03061194 0,04261252 ! oogenesis GO:0048477 44 24 0,000 0,03061194 0,04258826 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03061194 0,04256402 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03061194 0,04253981 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,03061194 0,04251562 ! platelet activation GO:0030168 41 24 0,000 0,03061194 0,04249147 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03061194 0,04246734 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03061194 0,04244324 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03061194 0,04241916 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03061194 0,04239511 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03061194 0,04237109 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03061194 0,0423471 ! regulation of amine transport GO:0051952 41 24 0,000 0,03061194 0,04232314 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03186735 0,04403389 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,03186735 0,044009 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03186735 0,04398414 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03186735 0,0439593 ! leukocyte adhesion GO:0007159 55 25 0,000 0,03186735 0,0439345 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03186735 0,04390972 ! phototransduction GO:0007602 37 25 0,000 0,03186735 0,04388496 ! keratinization GO:0031424 37 25 0,000 0,03186735 0,04386024 ! vasculogenesis GO:0001570 49 25 0,000 0,03186735 0,04383554 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03186735 0,04381088 ! vacuole organization GO:0007033 49 25 0,000 0,03186735 0,04378623 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03186735 0,04376162 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03186735 0,04373704 ! receptor metabolic process GO:0043112 53 25 0,000 0,03186735 0,04371248 ! chromosome condensation GO:0030261 48 25 0,000 0,03186735 0,04368795 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03186735 0,04366345 ! regulation of behavior GO:0050795 48 25 0,000 0,03186735 0,04363897 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03186735 0,04361452 ! interaction with host GO:0051701 66 25 0,000 0,03186735 0,0435901 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03186735 0,04356571 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03186735 0,04354135 ! immunoglobulin production GO:0002377 62 25 0,000 0,03186735 0,04351701 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03186735 0,0434927 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03186735 0,04346841 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03186735 0,04344415 ! liver development GO:0001889 55 25 0,000 0,03186735 0,04341992 ! protein tetramerization GO:0051262 57 25 0,000 0,03186735 0,04339572 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03312116 0,04507799 ! myelination GO:0042552 50 26 0,000 0,03312116 0,04505289 ! initiation of viral infection GO:0019059 60 26 0,000 0,03312116 0,04502782 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03312116 0,04500277 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03312116 0,04497776 ! molting cycle process GO:0022404 52 26 0,000 0,03312116 0,04495277 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03312116 0,04492781 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03312116 0,04490288 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03312116 0,04487797 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03312116 0,0448531 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,03312116 0,04482825 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03312116 0,04480342 ! digestive system process GO:0022600 49 26 0,000 0,03312116 0,04477863 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03312116 0,04475386 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03312116 0,04472912 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,03312116 0,04470441 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,03312116 0,04467973 ! neural crest cell development GO:0014032 59 26 0,000 0,03312116 0,04465507 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03312116 0,04463044 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03312116 0,04460584 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03312116 0,04458126 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03312116 0,04455671 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03312116 0,04453219 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03312116 0,04450769 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03312116 0,04448322 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,03312116 0,04445878 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03312116 0,04443437 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03312116 0,04440998 ! blastocyst development GO:0001824 50 26 0,000 0,03312116 0,04438562 ! telomere organization GO:0032200 46 26 0,000 0,03312116 0,04436129 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03312116 0,04433698 ! neural tube closure GO:0001843 58 26 0,000 0,03312116 0,0443127 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,03312116 0,04428844 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03312116 0,04426421 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03312116 0,04424001 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,03437338 0,04588752 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,03437338 0,04586246 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,03437338 0,04583743 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,03437338 0,04581242 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,03437338 0,04578744 ! iron ion transport GO:0006826 65 27 0,000 0,03437338 0,04576249 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,03437338 0,04573756 ! superoxide metabolic process GO:0006801 41 27 0,000 0,03437338 0,04571266 ! tube lumen formation GO:0035148 59 27 0,000 0,03437338 0,04568779 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,03437338 0,04566295 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,03437338 0,04563813 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,03437338 0,04561334 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,03437338 0,04558858 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,03437338 0,04556384 ! response to starvation GO:0042594 47 27 0,000 0,03437338 0,04553913 ! response to toxin GO:0009636 49 27 0,000 0,03437338 0,04551445 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,03437338 0,0454898 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,03437338 0,04546517 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,03437338 0,04544056 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,03437338 0,04541599 ! leukocyte proliferation GO:0070661 59 27 0,000 0,03437338 0,04539144 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,03437338 0,04536692 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,03562401 0,04699215 ! neuron fate commitment GO:0048663 52 28 0,000 0,03562401 0,04696679 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,03562401 0,04694146 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03562401 0,04691615 ! vesicle docking GO:0048278 55 28 0,000 0,03562401 0,04689088 ! circadian rhythm GO:0007623 56 28 0,000 0,03562401 0,04686563 ! dendrite development GO:0016358 67 28 0,000 0,03562401 0,0468404 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03562401 0,04681521 ! fat cell differentiation GO:0045444 57 28 0,000 0,03562401 0,04679004 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03562401 0,04676489 ! sperm motility GO:0030317 37 28 0,000 0,03562401 0,04673978 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03562401 0,04671469 ! base-excision repair GO:0006284 41 28 0,000 0,03562401 0,04668963 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03562401 0,04666459 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03562401 0,04663959 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03562401 0,0466146 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03562401 0,04658965 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03562401 0,04656472 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03562401 0,04653982 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03562401 0,04651495 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03562401 0,0464901 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03562401 0,04646528 ! lipid oxidation GO:0034440 48 28 0,000 0,03562401 0,04644048 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03562401 0,04641572 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03562401 0,04639097 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,03687307 0,04799195 ! translational initiation GO:0006413 66 29 0,000 0,03687307 0,0479664 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,03687307 0,04794087 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,03687307 0,04791537 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,03687307 0,0478899 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,03687307 0,04786445 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,03687307 0,04783903 ! primary neural tube formation GO:0014020 61 29 0,000 0,03687307 0,04781364 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,03687307 0,04778827 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,03687307 0,04776294 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,03687307 0,04773762 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,03687307 0,04771234 ! synaptogenesis GO:0007416 46 29 0,000 0,03687307 0,04768708 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,03687307 0,04766185 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,03687307 0,04763665 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,03687307 0,04761147 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,03687307 0,04758632 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,03812053 0,04917026 ! phenol metabolic process GO:0018958 56 30 0,000 0,03812053 0,04914431 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,03812053 0,04911839 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,03812053 0,0490925 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,03812053 0,04906663 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,03812053 0,04904079 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,03812053 0,04901498 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,03812053 0,0489892 ! acute-phase response GO:0006953 50 30 0,000 0,03812053 0,04896344 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,03812053 0,04893771 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,03812053 0,04891201 ! myofibril assembly GO:0030239 50 30 0,000 0,03812053 0,04888633 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,03812053 0,04886068 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,03812053 0,04883506 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,03812053 0,04880947 ! cell fate determination GO:0001709 64 30 0,000 0,03812053 0,0487839 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,03812053 0,04875836 ! phospholipid transport GO:0015914 65 30 0,000 0,03812053 0,04873284 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,03812053 0,04870736 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,03812053 0,04868189 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,03812053 0,04865646 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,03812053 0,04863105 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,03812053 0,04860567 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,03812053 0,04858031 ! regulation of coagulation GO:0050818 52 30 0,000 0,03812053 0,04855499 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,03936642 0,05011577 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,03936642 0,05008967 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,03936642 0,0500636 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,03936642 0,05003755 ! cell junction assembly GO:0034329 85 31 0,000 0,03936642 0,05001153 ! regulation of innate immune response GO:0045088 57 31 0,000 0,03936642 0,04998553 ! ovulation cycle process GO:0022602 55 31 0,000 0,03936642 0,04995957 ! peptide transport GO:0015833 60 31 0,000 0,03936642 0,04993363 ! male gonad development GO:0008584 56 31 0,000 0,03936642 0,04990772 ! iron ion homeostasis GO:0055072 60 31 0,000 0,03936642 0,04988183 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,03936642 0,04985597 ! detection of light stimulus GO:0009583 44 31 0,000 0,03936642 0,04983014 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,03936642 0,04980433 ! natural killer cell activation GO:0030101 50 31 0,000 0,03936642 0,04977855 ! ensheathment of neurons GO:0007272 64 31 0,000 0,03936642 0,0497528 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,03936642 0,04972708 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,03936642 0,04970138 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,03936642 0,04967571 ! eye morphogenesis GO:0048592 65 31 0,000 0,03936642 0,04965006 ! response to heat GO:0009408 54 31 0,000 0,03936642 0,04962444 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,03936642 0,04959885 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,04061073 0,05114021 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,04061073 0,05111387 ! collagen metabolic process GO:0032963 49 32 0,000 0,04061073 0,05108755 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,04061073 0,05106125 ! spindle organization GO:0007051 50 32 0,000 0,04061073 0,05103499 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,04061073 0,05100875 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,04061073 0,05098254 ! metanephros development GO:0001656 81 32 0,000 0,04061073 0,05095635 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,04061073 0,05093019 ! muscle cell development GO:0055001 52 32 0,000 0,04061073 0,05090406 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,04061073 0,05087796 ! ovulation cycle GO:0042698 57 32 0,000 0,04061073 0,05085188 ! peripheral nervous system development GO:0007422 68 32 0,000 0,04061073 0,05082583 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,04061073 0,0507998 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,04061073 0,0507738 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,04061073 0,05074783 ! gene silencing GO:0016458 71 32 0,000 0,04061073 0,05072189 ! regulation of pH GO:0006885 56 33 0,000 0,04185346 0,05224732 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,04185346 0,05222064 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,04185346 0,05219398 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,04185346 0,05216735 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,04185346 0,05214075 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,04185346 0,05211417 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,04185346 0,05208763 ! response to ionizing radiation GO:0010212 74 33 0,000 0,04185346 0,0520611 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,04185346 0,05203461 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,04185346 0,05200814 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,04185346 0,0519817 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,04185346 0,05195529 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,04185346 0,0519289 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,04185346 0,05190254 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,04185346 0,05187621 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04309462 0,0533875 ! glial cell differentiation GO:0010001 67 34 0,000 0,04309462 0,05336044 ! post-embryonic development GO:0009791 76 34 0,000 0,04309462 0,05333341 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04309462 0,05330641 ! cholesterol transport GO:0030301 62 34 0,000 0,04309462 0,05327943 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04309462 0,05325248 ! spliceosome assembly GO:0000245 75 34 0,000 0,04309462 0,05322556 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04309462 0,05319866 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04309462 0,0531718 ! cell fate specification GO:0001708 56 34 0,000 0,04309462 0,05314496 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,04309462 0,05311814 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04309462 0,05309135 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04309462 0,05306459 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,04309462 0,05303786 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0443342 0,05453598 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0443342 0,05450854 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0443342 0,05448112 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,0443342 0,05445373 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0443342 0,05442636 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0443342 0,05439903 ! membrane docking GO:0022406 69 35 0,000 0,0443342 0,05437172 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0443342 0,05434444 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0443342 0,05431718 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0443342 0,05428996 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0443342 0,05426276 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0443342 0,05423558 ! telencephalon development GO:0021537 81 35 0,000 0,0443342 0,05420844 ! sterol transport GO:0015918 63 35 0,000 0,0443342 0,05418132 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,0443342 0,05415423 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0443342 0,05412717 ! placenta development GO:0001890 53 35 0,000 0,0443342 0,05410013 ! vesicle localization GO:0051648 70 35 0,000 0,0443342 0,05407312 ! regulation of muscle development GO:0048634 82 36 0,000 0,04557222 0,05555535 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,04557222 0,05552765 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,04557222 0,05549996 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,04557222 0,05547231 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,04557222 0,05544469 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,04557222 0,05541709 ! positive regulation of cell development GO:0010720 85 36 0,000 0,04557222 0,05538952 ! protein targeting to membrane GO:0006612 75 36 0,000 0,04557222 0,05536197 ! regulation of proteolysis GO:0030162 77 36 0,000 0,04557222 0,05533446 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,04557222 0,05530697 ! aerobic respiration GO:0009060 56 36 0,000 0,04557222 0,05527951 ! embryonic organ development GO:0048568 67 36 0,000 0,04557222 0,05525207 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,04557222 0,05522467 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,04557222 0,05519729 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,04680866 0,05666678 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,04680866 0,05663871 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,04680866 0,05661067 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,04680866 0,05658266 ! sister chromatid segregation GO:0000819 65 37 0,000 0,04680866 0,05655468 ! odontogenesis GO:0042476 74 37 0,000 0,04680866 0,05652672 ! actomyosin structure organization GO:0031032 68 37 0,000 0,04680866 0,0564988 ! cell junction organization GO:0034330 96 37 0,000 0,04680866 0,0564709 ! tissue remodeling GO:0048771 78 37 0,000 0,04680866 0,05644302 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,04680866 0,05641518 ! female gonad development GO:0008585 71 37 0,000 0,04680866 0,05638736 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,04680866 0,05635957 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,04680866 0,0563318 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,04804354 0,05778945 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,04804354 0,05776101 ! meiosis I GO:0007127 74 38 0,000 0,04804354 0,0577326 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,04804354 0,05770421 ! organic anion transport GO:0015711 82 38 0,000 0,04804354 0,05767586 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,04804354 0,05764753 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,04804354 0,05761923 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,04804354 0,05759096 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,04804354 0,05756271 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,04804354 0,05753449 ! regulation of protein stability GO:0031647 77 38 0,000 0,04804354 0,05750631 ! spermatid development GO:0007286 69 38 0,000 0,04804354 0,05747814 ! pigment metabolic process GO:0042440 87 38 0,000 0,04804354 0,05745001 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,04804354 0,0574219 ! neural tube formation GO:0001841 79 38 0,000 0,04804354 0,05739382 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,04927685 0,05883839 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,04927685 0,05880965 ! negative regulation of binding GO:0051100 71 39 0,000 0,04927685 0,05878093 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,04927685 0,05875225 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,04927685 0,05872359 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,04927685 0,05869495 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,04927685 0,05866635 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,04927685 0,05863777 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,04927685 0,05860923 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,04927685 0,05858071 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,0505086 0,06001582 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,0505086 0,05998664 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,0505086 0,05995749 ! learning GO:0007612 82 40 0,000 0,0505086 0,05992837 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,0505086 0,05989928 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,0505086 0,05987022 ! lipid homeostasis GO:0055088 75 40 0,000 0,0505086 0,05984118 ! mismatch repair GO:0006298 58 40 0,000 0,0505086 0,05981217 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,0505086 0,0597832 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,0505086 0,05975424 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,0505086 0,05972532 ! RNA export from nucleus GO:0006405 61 41 0,000 0,05173879 0,06115039 ! mRNA catabolic process GO:0006402 79 41 0,000 0,05173879 0,06112082 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,05173879 0,06109128 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,05173879 0,06106177 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,05173879 0,06103229 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,05173879 0,06100283 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,05173879 0,0609734 ! gliogenesis GO:0042063 91 41 0,000 0,05173879 0,060944 ! feeding behavior GO:0007631 69 41 0,000 0,05173879 0,06091463 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,05173879 0,06088529 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,05173879 0,06085598 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,05173879 0,06082669 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,05173879 0,06079743 ! spermatid differentiation GO:0048515 73 41 0,000 0,05173879 0,0607682 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,05173879 0,060739 ! RNA modification GO:0009451 64 41 0,000 0,05173879 0,06070983 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,05296742 0,06212165 ! ear morphogenesis GO:0042471 64 42 0,000 0,05296742 0,06209185 ! organic ether metabolic process GO:0018904 59 42 0,000 0,05296742 0,06206207 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,05296742 0,06203231 ! T cell differentiation GO:0030217 93 42 0,000 0,05296742 0,06200259 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05296742 0,0619729 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05296742 0,06194323 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05296742 0,06191359 ! regulation of protein secretion GO:0050708 77 42 0,000 0,05296742 0,06188398 ! cytokinesis GO:0000910 84 42 0,000 0,05296742 0,0618544 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05296742 0,06182485 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05419449 0,06322691 ! regulation of tube size GO:0035150 76 43 0,000 0,05419449 0,06319673 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05419449 0,06316658 ! glucose transport GO:0015758 66 43 0,000 0,05419449 0,06313645 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,05419449 0,06310636 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05419449 0,06307629 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05419449 0,06304626 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05419449 0,06301625 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05419449 0,06298627 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05419449 0,06295632 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05419449 0,0629264 ! neuron migration GO:0001764 85 43 0,000 0,05419449 0,0628965 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,05419449 0,06286664 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,05542001 0,06425775 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,05542001 0,06422727 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,05542001 0,06419681 ! hexose transport GO:0008645 68 44 0,000 0,05542001 0,06416639 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,05542001 0,06413599 ! striated muscle contraction GO:0006941 85 44 0,000 0,05542001 0,06410562 ! phagocytosis GO:0006909 105 44 0,000 0,05542001 0,06407529 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,05542001 0,06404498 ! double-strand break repair GO:0006302 85 44 0,000 0,05542001 0,06401469 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,05664397 0,06539755 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,05664397 0,06536666 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,05664397 0,0653358 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,05664397 0,06530496 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,05664397 0,06527416 ! biopolymer methylation GO:0043414 91 45 0,000 0,05664397 0,06524339 ! B cell differentiation GO:0030183 124 45 0,000 0,05664397 0,06521264 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,05664397 0,06518192 ! female gamete generation GO:0007292 71 45 0,000 0,05664397 0,06515123 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,05664397 0,06512057 ! polyol metabolic process GO:0019751 77 45 0,000 0,05664397 0,06508994 ! developmental growth GO:0048589 88 45 0,000 0,05664397 0,06505934 ! maintenance of location in cell GO:0051651 101 45 0,000 0,05664397 0,06502877 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,05786638 0,06640093 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,05786638 0,06636975 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,05786638 0,06633861 ! glycolysis GO:0006096 71 46 0,000 0,05786638 0,06630749 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,05786638 0,0662764 ! leukocyte migration GO:0050900 75 46 0,000 0,05786638 0,06624535 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,05786638 0,06621432 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,05786638 0,06618332 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,05786638 0,06615235 ! pigmentation GO:0043473 103 46 0,000 0,05786638 0,06612141 ! cell growth GO:0016049 90 46 0,000 0,05786638 0,0660905 ! neural tube development GO:0021915 91 47 0,000 0,05908724 0,06745333 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,05908724 0,06742183 ! response to insulin stimulus GO:0032868 98 47 0,000 0,05908724 0,06739035 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,06030656 0,06874891 ! positive regulation of defense response GO:0031349 88 48 0,000 0,06030656 0,06871685 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,06030656 0,06868481 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,06030656 0,0686528 ! cellular component disassembly GO:0022411 89 48 0,000 0,06030656 0,06862083 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,06030656 0,06858888 ! endosome transport GO:0016197 127 48 0,000 0,06030656 0,06855697 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,06030656 0,06852508 ! male sex differentiation GO:0046661 93 48 0,000 0,06030656 0,06849322 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,06030656 0,06846139 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,06030656 0,0684296 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,06030656 0,06839783 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,06030656 0,06836609 ! methylation GO:0032259 97 48 0,000 0,06030656 0,06833438 ! response to calcium ion GO:0051592 94 49 0,000 0,06152433 0,06968193 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,06152433 0,06964964 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,06152433 0,06961738 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,06152433 0,06958515 ! JNK cascade GO:0007254 106 49 0,000 0,06152433 0,06955295 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,06152433 0,06952078 ! regulation of action potential GO:0001508 102 50 0,000 0,06274055 0,0708623 ! regulation of ion transport GO:0043269 86 50 0,000 0,06274055 0,07082956 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,06274055 0,07079684 ! endocrine system development GO:0035270 109 50 0,000 0,06274055 0,07076416 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,06274055 0,0707315 ! activation of caspase activity GO:0006919 95 50 0,000 0,06274055 0,07069888 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,06274055 0,07066628 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,06274055 0,07063372 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,06274055 0,07060118 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,06274055 0,07056868 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,06274055 0,0705362 ! viral infectious cycle GO:0019058 104 51 0,000 0,06395523 0,07186874 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,06395523 0,07183569 ! peptide metabolic process GO:0006518 80 51 0,000 0,06395523 0,07180268 ! response to temperature stimulus GO:0009266 84 51 0,000 0,06395523 0,0717697 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,06395523 0,07173675 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,06395523 0,07170382 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,06516837 0,07303043 ! Notch signaling pathway GO:0007219 111 52 0,000 0,06516837 0,07299695 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,06516837 0,07296349 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,06516837 0,07293007 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,06516837 0,07289668 ! excretion GO:0007588 87 52 0,000 0,06516837 0,07286331 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,06516837 0,07282998 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,06516837 0,07279668 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,06516837 0,07276341 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,06516837 0,07273017 ! amino acid activation GO:0043038 98 52 0,000 0,06516837 0,07269696 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,06637998 0,07401474 ! positive regulation of growth GO:0045927 96 53 0,000 0,06637998 0,07398097 ! inner ear development GO:0048839 89 53 0,000 0,06637998 0,07394724 ! chromatin remodeling GO:0006338 122 53 0,000 0,06637998 0,07391353 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,06637998 0,07387986 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,06637998 0,07384621 ! vesicle organization GO:0016050 127 53 0,000 0,06637998 0,0738126 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,06637998 0,07377902 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,06637998 0,07374547 ! cartilage development GO:0051216 99 53 0,000 0,06637998 0,07371195 ! synapse organization GO:0050808 102 53 0,000 0,06637998 0,07367846 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,06759005 0,0749875 ! regulation of translational initiation GO:0006446 87 54 0,000 0,06759005 0,07495347 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,06759005 0,07491946 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,06759005 0,07488548 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,06759005 0,07485153 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,06759005 0,07481762 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,06759005 0,07478373 ! membrane fusion GO:0006944 122 54 0,000 0,06759005 0,07474988 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,06759005 0,07471606 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,06759005 0,07468226 ! regulation of cell shape GO:0008360 142 54 0,000 0,06759005 0,0746485 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,06759005 0,07461477 ! RNA catabolic process GO:0006401 103 55 0,000 0,06879858 0,0759146 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,06879858 0,07588033 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,06879858 0,07584609 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,06879858 0,07581188 ! cell recognition GO:0008037 98 55 0,000 0,06879858 0,0757777 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,06879858 0,07574355 ! cell maturation GO:0048469 107 55 0,000 0,06879858 0,07570943 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,06879858 0,07567534 ! response to UV GO:0009411 120 55 0,000 0,06879858 0,07564128 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,06879858 0,07560726 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,07000558 0,07689912 ! glucose catabolic process GO:0006007 88 56 0,000 0,07000558 0,07686456 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,07000558 0,07683002 ! regulation of DNA replication GO:0006275 105 56 0,000 0,07000558 0,07679553 ! RNA elongation GO:0006354 90 56 0,000 0,07000558 0,07676106 ! chloride transport GO:0006821 102 57 0,000 0,07121105 0,07804782 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,07121105 0,07801283 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,07121105 0,07797786 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,07121105 0,07794292 ! heart morphogenesis GO:0003007 105 57 0,000 0,07121105 0,07790802 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,07121105 0,07787314 ! regulation of actin filament length GO:0030832 118 58 0,000 0,07241499 0,07915429 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,07241499 0,07911889 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,07241499 0,07908352 ! aging GO:0007568 112 58 0,000 0,07241499 0,07904818 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,07241499 0,07901288 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,07241499 0,0789776 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,07241499 0,07894236 ! maintenance of location GO:0051235 124 58 0,000 0,07241499 0,07890715 ! nuclear export GO:0051168 110 59 0,000 0,07361741 0,0801816 ! establishment of organelle localization GO:0051656 122 59 0,000 0,07361741 0,08014587 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,0748183 0,08141697 ! lipid modification GO:0030258 112 60 0,000 0,0748183 0,08138072 ! DNA catabolic process GO:0006308 94 60 0,000 0,0748183 0,08134451 ! regulation of endocytosis GO:0030100 104 60 0,000 0,0748183 0,08130832 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,0748183 0,08127217 ! adult behavior GO:0030534 104 60 0,000 0,0748183 0,08123605 ! kidney development GO:0001822 133 60 0,000 0,0748183 0,08119996 ! positive regulation of secretion GO:0051047 110 61 0,000 0,07601767 0,08246499 ! regulation of cellular component size GO:0032535 125 61 0,000 0,07601767 0,08242839 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,07601767 0,08239182 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,07601767 0,08235528 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,07601767 0,08231878 ! regulation of heart contraction GO:0008016 123 61 0,000 0,07601767 0,0822823 ! proton transport GO:0015992 117 61 0,000 0,07601767 0,08224586 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,07601767 0,08220946 ! viral reproductive process GO:0022415 132 62 0,000 0,07721551 0,08346792 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,07721551 0,083431 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,07721551 0,08339412 ! tRNA processing GO:0008033 102 62 0,000 0,07721551 0,08335727 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,07721551 0,08332045 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,07841184 0,08457401 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,07841184 0,08453668 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,07841184 0,08449939 ! hydrogen transport GO:0006818 121 64 0,000 0,07960665 0,08574914 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,07960665 0,08571135 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,07960665 0,08567359 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,07960665 0,08563586 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,07960665 0,08559817 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,08079995 0,08684306 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,08079995 0,08680487 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,08079995 0,08676671 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,08079995 0,08672859 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,08079995 0,0866905 ! ear development GO:0043583 114 66 0,000 0,08199173 0,08793055 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,08199173 0,08789197 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,08199173 0,08785342 ! gonad development GO:0008406 115 66 0,000 0,08199173 0,0878149 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,083182 0,08905066 ! activation of MAPK activity GO:0000187 124 67 0,000 0,083182 0,08901166 ! chromosome segregation GO:0007059 127 67 0,000 0,083182 0,08897269 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,083182 0,08893375 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,083182 0,08889485 ! secondary metabolic process GO:0019748 125 67 0,000 0,083182 0,08885598 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,083182 0,08881714 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,08437076 0,09004708 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,08437076 0,09000775 ! hexose catabolic process GO:0019320 113 68 0,000 0,08437076 0,08996847 ! extracellular matrix organization GO:0030198 146 68 0,000 0,08437076 0,08992921 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,08437076 0,08988999 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,08437076 0,08985081 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,08437076 0,08981166 ! viral reproduction GO:0016032 142 68 0,000 0,08437076 0,08977254 ! regulation of lipase activity GO:0060191 137 68 0,000 0,08437076 0,08973346 ! adaptive immune response GO:0002250 126 68 0,000 0,08437076 0,08969441 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,08437076 0,0896554 ! negative regulation of cell size GO:0045792 144 69 0,000 0,08555801 0,09087748 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,08555801 0,09083799 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,08555801 0,09079853 ! urogenital system development GO:0001655 149 69 0,000 0,08555801 0,0907591 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,08555801 0,09071971 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,08555801 0,09068035 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,08555801 0,09064103 ! developmental maturation GO:0021700 128 69 0,000 0,08555801 0,09060174 ! single fertilization GO:0007338 83 69 0,000 0,08555801 0,09056248 ! cell redox homeostasis GO:0045454 114 70 0,000 0,08674375 0,09177782 ! germ cell development GO:0007281 133 70 0,000 0,08674375 0,09173809 ! activation of immune response GO:0002253 120 70 0,000 0,08674375 0,09169839 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,08674375 0,09165873 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,087928 0,09286991 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,087928 0,09282977 ! carbohydrate transport GO:0008643 114 72 0,000 0,08911073 0,09403781 ! actin filament organization GO:0007015 167 72 0,000 0,08911073 0,0939972 ! B cell activation GO:0042113 179 72 0,000 0,08911073 0,09395664 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,08911073 0,0939161 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,08911073 0,0938756 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,08911073 0,09383514 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,08911073 0,09379471 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,08911073 0,09375432 ! humoral immune response GO:0006959 115 73 0,000 0,09029197 0,09495622 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,09029197 0,09491536 ! regulation of immune effector process GO:0002697 156 73 0,000 0,09029197 0,09487453 ! acute inflammatory response GO:0002526 118 74 0,000 0,09147171 0,09607283 ! amino acid transport GO:0006865 148 74 0,000 0,09147171 0,09603154 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,09147171 0,09599029 ! organelle localization GO:0051640 155 74 0,000 0,09147171 0,09594908 ! transition metal ion transport GO:0000041 143 75 0,000 0,09264996 0,09714328 ! reproductive structure development GO:0048608 131 75 0,000 0,09264996 0,09710161 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,09264996 0,09705997 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,09264996 0,09701837 ! axon guidance GO:0007411 162 75 0,000 0,09264996 0,0969768 ! rhythmic process GO:0048511 142 75 0,000 0,09264996 0,09693527 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,09382671 0,09812442 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,09382671 0,09808243 ! learning or memory GO:0007611 161 76 0,000 0,09382671 0,09804048 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,09382671 0,09799857 ! regulation of blood pressure GO:0008217 134 76 0,000 0,09382671 0,09795669 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,09382671 0,09791484 ! amine catabolic process GO:0009310 136 77 0,000 0,09500196 0,09909897 ! neurotransmitter transport GO:0006836 142 77 0,000 0,09500196 0,09905668 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,09500196 0,09901442 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,09500196 0,09897219 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,09500196 0,09893001 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,09500196 0,09888785 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,09500196 0,09884574 ! regulation of catabolic process GO:0009894 173 77 0,000 0,09500196 0,09880366 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,09617573 0,09998183 ! antigen processing and presentation GO:0019882 117 78 0,000 0,09617573 0,0999393 ! fertilization GO:0009566 99 78 0,000 0,09617573 0,09989681 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,09617573 0,09985436 ! blood coagulation GO:0007596 151 79 0,000 0,097348 0,10102853 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,097348 0,10098563 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,097348 0,10094277 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,097348 0,10089994 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,097348 0,10085715 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,097348 0,1008144 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,09851879 0,10198365 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,09851879 0,10194045 ! meiosis GO:0007126 143 81 0,000 0,09968809 0,10310669 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,09968809 0,10306306 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,09968809 0,10301946 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,09968809 0,1029759 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,10085591 0,1041382 ! protein import into nucleus GO:0006606 174 82 0,000 0,10085591 0,10409421 ! meiotic cell cycle GO:0051321 144 82 0,000 0,10085591 0,10405025 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,10202225 0,1052091 ! exocytosis GO:0006887 153 83 0,000 0,10202225 0,1051647 ! response to drug GO:0042493 149 83 0,000 0,10202225 0,10512035 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,10202225 0,10507603 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,10202225 0,10503175 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,10202225 0,10498751 ! nuclear import GO:0051170 177 83 0,000 0,10202225 0,10494331 ! inorganic anion transport GO:0015698 156 83 0,000 0,10202225 0,10489914 ! response to metal ion GO:0010038 158 84 0,000 0,1031871 0,10605221 ! T cell activation GO:0042110 189 84 0,000 0,1031871 0,10600761 ! response to nutrient GO:0007584 135 84 0,000 0,1031871 0,10596305 ! digestion GO:0007586 130 84 0,000 0,1031871 0,10591853 ! regulation of ligase activity GO:0051340 147 84 0,000 0,1031871 0,10587404 ! hemostasis GO:0007599 165 85 0,000 0,10435048 0,10702277 ! negative regulation of transport GO:0051051 164 85 0,000 0,10435048 0,10697785 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,10435048 0,10693298 ! negative regulation of growth GO:0045926 168 85 0,000 0,10435048 0,10688815 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,10435048 0,10684335 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,10435048 0,10679859 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,10435048 0,10675386 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,10435048 0,10670918 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,10551238 0,1078522 ! regulation of lyase activity GO:0051339 169 86 0,000 0,10551238 0,10780709 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,10551238 0,10776202 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,10667281 0,10890166 ! mitochondrion organization GO:0007005 159 87 0,000 0,10667281 0,10885617 ! alcohol catabolic process GO:0046164 142 87 0,000 0,10667281 0,10881072 ! nucleosome assembly GO:0006334 126 87 0,000 0,10667281 0,10876531 ! cellular respiration GO:0045333 143 88 0,000 0,10783177 0,10990113 ! amine biosynthetic process GO:0009309 146 88 0,000 0,10783177 0,1098553 ! sensory perception of smell GO:0007608 117 88 0,000 0,10783177 0,10980951 ! chromatin assembly GO:0031497 128 88 0,000 0,10783177 0,10976375 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,10783177 0,10971804 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,10898925 0,1108496 ! tube morphogenesis GO:0035239 194 89 0,000 0,10898925 0,11080347 ! cellular defense response GO:0006968 123 89 0,000 0,10898925 0,11075738 ! protein localization in nucleus GO:0034504 192 89 0,000 0,10898925 0,11071132 ! regulation of neurological system process GO:0031644 175 89 0,000 0,10898925 0,11066531 ! response to inorganic substance GO:0010035 173 90 0,000 0,11014526 0,11179264 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,11014526 0,11174621 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,11014526 0,11169983 ! response to unfolded protein GO:0006986 139 90 0,000 0,11014526 0,11165348 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,11129981 0,11277704 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,11129981 0,11273028 ! defense response to bacterium GO:0042742 112 91 0,000 0,11129981 0,11268356 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,11245289 0,11380382 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,11245289 0,11375669 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,11360451 0,1148741 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,11360451 0,11482657 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,11360451 0,11477908 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,11360451 0,11473163 ! vitamin metabolic process GO:0006766 153 93 0,000 0,11360451 0,11468422 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,11475467 0,11579746 ! female pregnancy GO:0007565 166 94 0,000 0,11475467 0,11574965 ! sterol metabolic process GO:0016125 166 94 0,000 0,11475467 0,11570188 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,11475467 0,11565415 ! regulation of membrane potential GO:0042391 179 94 0,000 0,11475467 0,11560645 ! regulation of defense response GO:0031347 171 95 0,000 0,11590336 0,11671555 ! nucleosome organization GO:0034728 143 95 0,000 0,11590336 0,11666746 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,11590336 0,11661941 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,11590336 0,11657139 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,11590336 0,11652342 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,11590336 0,11647549 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,11590336 0,1164276 ! sex differentiation GO:0007548 171 96 0,000 0,1170506 0,1175317 ! response to protein stimulus GO:0051789 158 96 0,000 0,1170506 0,11748341 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1170506 0,11743516 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,11819638 0,11853603 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,11819638 0,11848739 ! transcription initiation GO:0006352 171 97 0,000 0,11819638 0,11843879 ! leukocyte differentiation GO:0002521 232 98 0,000 0,11934071 0,11953643 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,11934071 0,11948744 ! mRNA transport GO:0051028 185 100 0,000 0,12162501 0,12172466 ! positive regulation of immune response GO:0050778 175 100 0,000 0,12162501 0,12167481 ! hormone metabolic process GO:0042445 171 100 0,000 0,12162501 0,12162501