pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/678-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! DNA integration GO:0015074 32 18 2,000 6,633E-06 0,01620467 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,076E-05 0,01314765 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,631E-05 0,01327983 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 2,922E-05 0,01784874 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,144E-05 0,02024661 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 4,144E-05 0,01687218 ! negative regulation of T cell mediated immunity GO:0002710 15 5 1,000 4,144E-05 0,01446187 GO:0002707|negative regulation of lymphocyte mediated immunity, ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 1,000 4,144E-05 0,01265413 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 1,000 4,144E-05 0,01124812 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 1,000 4,144E-05 0,01012331 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 1,000 4,144E-05 9,203E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 4,163E-05 8,475E-03 ! regulation of ARF GTPase activity GO:0032312 73 34 2,000 4,751E-05 8,928E-03 ! thymic T cell selection GO:0045061 16 6 1,000 6,207E-05 0,01083196 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 1,000 6,207E-05 0,01010983 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,679E-05 0,01325149 ! positive regulation of isotype switching GO:0045830 17 7 1,000 8,679E-05 0,01247199 GO:0045911|positive regulation of DNA recombination, ! vesicle fusion GO:0006906 20 7 1,000 8,679E-05 0,0117791 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 1,000 8,679E-05 0,01115915 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 1,000 8,679E-05 0,01060119 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 8,679E-05 0,01009638 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,108E-04 0,01230873 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,156E-04 0,01227488 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,156E-04 0,01176343 ! gas homeostasis GO:0033483 14 8 1,000 1,156E-04 0,01129289 ! B cell receptor signaling pathway GO:0050853 22 8 1,000 1,156E-04 0,01085855 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 1,156E-04 0,01045638 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,156E-04 0,01008294 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,156E-04 9,735E-03 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,345E-04 0,01095363 ! protein homooligomerization GO:0051260 84 49 2,000 1,431E-04 0,01127499 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,484E-04 0,01132821 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,484E-04 0,01098493 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 1,000 1,484E-04 0,01066185 GO:0002820|negative regulation of adaptive immune response, ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 1,484E-04 0,01035722 GO:0010469|regulation of receptor activity, ! T cell selection GO:0045058 27 9 1,000 1,484E-04 0,01006952 ! regulation of ARF protein signal transduction GO:0032012 115 50 2,000 1,52E-04 0,0100348 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 1,852E-04 0,01190857 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,852E-04 0,01160322 ! regulation of B cell differentiation GO:0045577 24 10 1,000 1,852E-04 0,01131314 ! induction of an organ GO:0001759 17 10 1,000 1,852E-04 0,01103721 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,852E-04 0,01077442 ! negative regulation of immune effector process GO:0002698 23 10 1,000 1,852E-04 0,01052385 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,261E-04 0,01255344 ! positive regulation of T cell mediated immunity GO:0002711 26 11 1,000 2,261E-04 0,01227447 ! regulation of isotype switching GO:0045191 24 11 1,000 2,261E-04 0,01200764 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 2,261E-04 0,01175215 ! positive regulation of organelle organization GO:0010638 108 58 2,000 2,365E-04 0,01203474 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,71E-04 0,01350898 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,71E-04 0,0132388 ! T cell proliferation GO:0042098 32 12 1,000 2,71E-04 0,01297921 ! mRNA polyadenylation GO:0006378 24 12 1,000 2,71E-04 0,01272961 ! developmental induction GO:0031128 22 12 1,000 2,71E-04 0,01248943 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 2,71E-04 0,01225815 ! organelle fusion GO:0048284 36 13 1,000 3,198E-04 0,01420459 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,198E-04 0,01395093 ! gland morphogenesis GO:0022612 31 13 1,000 3,198E-04 0,01370618 ! mRNA 3'-end processing GO:0031124 25 13 1,000 3,198E-04 0,01346987 ! activation of MAPK activity GO:0000187 124 67 2,000 3,623E-04 0,01500084 ! regulation of S phase GO:0033261 26 14 1,000 3,726E-04 0,01517082 ! RNA polyadenylation GO:0043631 32 14 1,000 3,726E-04 0,01492212 ! lipid localization GO:0010876 32 14 1,000 3,726E-04 0,01468144 GO:0019915|lipid storage, ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 3,726E-04 0,0144484 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 3,726E-04 0,01422264 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 37 14 1,000 3,726E-04 0,01400383 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 3,726E-04 0,01379165 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 3,951E-04 0,01440509 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 3,951E-04 0,01419325 ! negative regulation of kinase activity GO:0033673 145 70 2,000 4,121E-04 0,01459238 ! positive regulation of axonogenesis GO:0050772 33 15 1,000 4,293E-04 0,01498416 ! regulation of vasodilation GO:0042312 27 15 1,000 4,293E-04 0,01477312 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 4,293E-04 0,01456793 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 4,477E-04 0,01498331 ! negative regulation of transferase activity GO:0051348 155 74 2,000 4,852E-04 0,01601844 ! heterophilic cell adhesion GO:0007157 43 16 1,000 4,9E-04 0,01596186 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 4,9E-04 0,01575183 ! negative regulation of immune response GO:0050777 38 16 1,000 4,9E-04 0,01554727 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,9E-04 0,01534794 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 1,000 4,9E-04 0,01515366 ! positive regulation of cell killing GO:0031343 36 17 1,000 5,546E-04 0,01693694 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 5,546E-04 0,01672784 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 1,000 5,546E-04 0,01652384 GO:0002712|regulation of B cell mediated immunity, ! RNA 3'-end processing GO:0031123 37 17 1,000 5,546E-04 0,01632476 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 5,546E-04 0,01613041 ! protein oligomerization GO:0051259 149 79 2,000 5,876E-04 0,01688754 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 6,231E-04 0,01770115 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 6,231E-04 0,01749768 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 6,231E-04 0,01729885 ! defense response to virus GO:0051607 43 18 1,000 6,231E-04 0,01710448 ! regulation of peptidase activity GO:0052547 150 82 2,000 6,551E-04 0,01778299 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 6,955E-04 0,01867178 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 7,718E-04 0,02049366 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,718E-04 0,02027329 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,718E-04 0,02005762 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 7,718E-04 0,01984649 ! regulation of cell killing GO:0031341 46 21 1,000 8,519E-04 0,02167826 ! lipid phosphorylation GO:0046834 43 21 1,000 8,519E-04 0,02145478 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 1,000 8,519E-04 0,02123585 ! regulation of vasoconstriction GO:0019229 40 21 1,000 8,519E-04 0,02102135 ! regulation of cell cycle process GO:0010564 161 90 2,000 8,589E-04 0,02098315 ! inactivation of MAPK activity GO:0000188 45 22 1,000 9,358E-04 0,02263549 ! ureteric bud development GO:0001657 50 22 1,000 9,358E-04 0,02241357 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 9,358E-04 0,02219597 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 9,358E-04 0,02198254 ! positive regulation of B cell activation GO:0050871 42 22 1,000 9,358E-04 0,02177319 ! regulation of DNA recombination GO:0000018 51 23 1,000 1,024E-03 0,02359049 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 1,115E-03 0,02546071 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,115E-03 0,02522496 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 1,115E-03 0,02499354 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,115E-03 0,02476633 ! membrane depolarization GO:0051899 45 24 1,000 1,115E-03 0,02454321 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,115E-03 0,02432407 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,115E-03 0,02410882 ! leukocyte adhesion GO:0007159 55 25 1,000 1,211E-03 0,02594088 ! vasculogenesis GO:0001570 49 25 1,000 1,211E-03 0,02571531 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 1,211E-03 0,02549363 ! lymphocyte proliferation GO:0046651 55 25 1,000 1,211E-03 0,02527573 ! immunoglobulin production GO:0002377 62 25 1,000 1,211E-03 0,02506153 GO:0002440|production of molecular mediator of immune response, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,31E-03 0,02688611 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,31E-03 0,02666206 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,31E-03 0,02644171 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,31E-03 0,02622497 ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 1,31E-03 0,02601176 ! regulation of blood coagulation GO:0030193 46 26 1,000 1,31E-03 0,02580199 ! positive regulation of nuclear division GO:0051785 41 26 1,000 1,31E-03 0,02559557 GO:0045840|positive regulation of mitosis, ! positive regulation of cell projection organization GO:0031346 66 27 1,000 1,413E-03 0,02738744 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,413E-03 0,02717179 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 1,413E-03 0,02695951 ! leukocyte proliferation GO:0070661 59 27 1,000 1,413E-03 0,02675052 GO:0032943|mononuclear cell proliferation, ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,519E-03 0,02854872 ! vesicle docking GO:0048278 55 28 1,000 1,519E-03 0,02833079 ! negative regulation of protein modification process GO:0031400 66 28 1,000 1,519E-03 0,02811616 ! positive regulation of T cell differentiation GO:0045582 48 28 1,000 1,519E-03 0,02790476 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 1,63E-03 0,02970864 ! synaptogenesis GO:0007416 46 29 1,000 1,63E-03 0,02948858 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 1,744E-03 0,03132099 ! immune response-activating signal transduction GO:0002757 58 30 1,000 1,744E-03 0,03109237 GO:0002764|immune response-regulating signal transduction, ! regulation of B cell activation GO:0050864 55 30 1,000 1,744E-03 0,03086706 ! regulation of coagulation GO:0050818 52 30 1,000 1,744E-03 0,030645 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 1,861E-03 0,03248132 ! positive regulation of immune effector process GO:0002699 78 31 1,000 1,861E-03 0,03225096 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 1,983E-03 0,03411346 ! metanephros development GO:0001656 81 32 1,000 1,983E-03 0,03387491 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,983E-03 0,03363966 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 1,000 1,983E-03 0,03340767 ! cholesterol homeostasis GO:0042632 60 33 1,000 2,108E-03 0,03527259 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 2,108E-03 0,03503264 ! regulation of axonogenesis GO:0050770 86 33 1,000 2,108E-03 0,03479593 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 2,108E-03 0,0345624 ! cholesterol transport GO:0030301 62 34 1,000 2,237E-03 0,03642937 ! cell fate specification GO:0001708 56 34 1,000 2,237E-03 0,03618812 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,237E-03 0,03595004 ! membrane docking GO:0022406 69 35 1,000 2,369E-03 0,03782941 ! sterol transport GO:0015918 63 35 1,000 2,369E-03 0,03758377 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,369E-03 0,03734129 ! positive regulation of cell development GO:0010720 85 36 1,000 2,505E-03 0,03923233 ! tissue remodeling GO:0048771 78 37 1,000 2,645E-03 0,0411554 ! regulation of microtubule-based process GO:0032886 86 37 1,000 2,645E-03 0,04089492 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 2,788E-03 0,04283854 ! neutral lipid metabolic process GO:0006638 54 38 1,000 2,788E-03 0,0425708 GO:0006639|acylglycerol metabolic process, ! cellular response to insulin stimulus GO:0032869 85 38 1,000 2,788E-03 0,04230638 ! regulation of neuron projection development GO:0010975 102 39 1,000 2,935E-03 0,04425924 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 2,935E-03 0,04398771 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 2,935E-03 0,04371949 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 2,935E-03 0,04345452 ! mammary gland development GO:0030879 93 40 1,000 3,085E-03 0,04540583 ! lipid homeostasis GO:0055088 75 40 1,000 3,085E-03 0,04513394 ! glycerol ether metabolic process GO:0006662 57 40 1,000 3,085E-03 0,04486529 ! organic ether metabolic process GO:0018904 59 42 1,000 3,397E-03 0,04910103 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 3,397E-03 0,0488122 ! T cell differentiation GO:0030217 93 42 1,000 3,397E-03 0,04852675 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 3,397E-03 0,04824461 ! regulation of T cell differentiation GO:0045580 78 42 1,000 3,397E-03 0,04796574 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 3,558E-03 0,04995021 ! regulation of T cell proliferation GO:0042129 80 43 1,000 3,558E-03 0,04966478 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 3,89E-03 0,05399715 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 3,89E-03 0,05369208 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 4,062E-03 0,05574341 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 4,062E-03 0,055432 ! cell growth GO:0016049 90 46 1,000 4,062E-03 0,05512404 ! positive regulation of protein transport GO:0051222 80 46 1,000 4,062E-03 0,05481949 ! response to insulin stimulus GO:0032868 98 47 1,000 4,236E-03 0,05686598 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 4,415E-03 0,05893608 ! regulation of adaptive immune response GO:0002819 92 48 1,000 4,415E-03 0,05861578 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 4,597E-03 0,06069935 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 4,597E-03 0,06037301 ! regulation of cell projection organization GO:0031344 135 51 1,000 4,97E-03 0,06493331 ! negative regulation of immune system process GO:0002683 101 51 1,000 4,97E-03 0,06458792 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 5,162E-03 0,06672769 ! vesicle organization GO:0016050 127 53 1,000 5,358E-03 0,06888831 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 5,358E-03 0,06852764 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 102 53 1,000 5,358E-03 0,06817072 ! activation of phospholipase C activity GO:0007202 110 54 1,000 5,556E-03 0,07033278 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 5,556E-03 0,06997024 ! membrane fusion GO:0006944 122 54 1,000 5,556E-03 0,06961142 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 5,556E-03 0,06925626 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 5,758E-03 0,07141039 ! regulation of protein polymerization GO:0032271 117 55 1,000 5,758E-03 0,07104973 ! response to UV GO:0009411 120 55 1,000 5,758E-03 0,07069269 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 6,173E-03 0,07539727 ! regulation of phospholipase activity GO:0010517 113 57 1,000 6,173E-03 0,07502216 ! regulation of intracellular transport GO:0032386 108 57 1,000 6,173E-03 0,07465077 ! positive regulation of cell migration GO:0030335 137 58 1,000 6,385E-03 0,07683436 ! positive regulation of lipase activity GO:0060193 115 58 1,000 6,385E-03 0,07645772 ! lipid modification GO:0030258 112 60 1,000 6,818E-03 0,08125502 ! kidney development GO:0001822 133 60 1,000 6,818E-03 0,08086058 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 7,04E-03 0,08308789 ! regulation of homeostatic process GO:0032844 148 62 1,000 7,265E-03 0,08533191 ! regulation of protein complex assembly GO:0043254 132 63 1,000 7,494E-03 0,08759223 ! regulation of mitosis GO:0007088 112 63 1,000 7,494E-03 0,08717512 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 7,494E-03 0,08676197 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 7,725E-03 0,08902064 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 7,725E-03 0,08860271 ! positive regulation of cell motion GO:0051272 157 65 1,000 7,96E-03 0,09086825 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 8,198E-03 0,09314897 ! extracellular matrix organization GO:0030198 146 68 1,000 8,683E-03 0,09820705 ! positive regulation of T cell activation GO:0050870 124 68 1,000 8,683E-03 0,09775449 ! regulation of lipase activity GO:0060191 137 68 1,000 8,683E-03 0,09730607 ! lung development GO:0030324 165 69 1,000 8,93E-03 0,0996216 ! urogenital system development GO:0001655 149 69 1,000 8,93E-03 0,09916877 ! activation of immune response GO:0002253 120 70 1,000 9,181E-03 0,10148957 ! respiratory tube development GO:0030323 171 72 1,000 9,691E-03 0,10664945 ! regulation of immune effector process GO:0002697 156 73 1,000 9,951E-03 0,10901807 ! regulation of caspase activity GO:0043281 136 74 1,000 0,01021425 0,11139915 ! respiratory system development GO:0060541 175 74 1,000 0,01021425 0,11090404 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01022744 0,11055593 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01022744 0,1100689 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01022744 0,10958614 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01022744 0,1091076 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01022744 0,10863322 ! neuron fate determination GO:0048664 7 5 0,000 0,01022744 0,10816294 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01022744 0,10769672 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01022744 0,1072345 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01022744 0,10677624 ! polyol transport GO:0015791 12 5 0,000 0,01022744 0,10632187 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01022744 0,10587135 ! response to superoxide GO:0000303 10 5 0,000 0,01022744 0,10542464 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01022744 0,10498168 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01022744 0,10454242 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01022744 0,10410683 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01022744 0,10367485 ! female meiosis GO:0007143 10 5 0,000 0,01022744 0,10324644 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01022744 0,10282156 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01022744 0,10240016 ! hypothalamus development GO:0021854 9 5 0,000 0,01022744 0,1019822 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01022744 0,10156764 ! cobalt ion transport GO:0006824 11 5 0,000 0,01022744 0,10115644 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01022744 0,10074855 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01022744 0,10034393 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01022744 0,09994256 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01022744 0,09954438 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01022744 0,09914936 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01022744 0,09875747 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01022744 0,09836866 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01022744 0,0979829 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01022744 0,09760015 ! transposition GO:0032196 9 5 0,000 0,01022744 0,09722039 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01022744 0,09684356 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01022744 0,09646965 ! negative chemotaxis GO:0050919 16 5 0,000 0,01022744 0,09609861 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01022744 0,09573042 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01022744 0,09536504 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01022744 0,09500243 ! behavioral response to pain GO:0048266 10 5 0,000 0,01022744 0,09464257 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01022744 0,09428543 ! Notch receptor processing GO:0007220 11 5 0,000 0,01022744 0,09393098 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01022744 0,09357917 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01022744 0,09323 ! micturition GO:0060073 9 5 0,000 0,01022744 0,09288342 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01022744 0,09253941 ! copulation GO:0007620 9 5 0,000 0,01022744 0,09219793 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01022744 0,09185897 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01022744 0,09152249 ! bioluminescence GO:0008218 9 5 0,000 0,01022744 0,09118847 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01022744 0,09085687 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01022744 0,09052768 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01022744 0,09020086 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01022744 0,0898764 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01022744 0,08955426 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01022744 0,08923443 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01022744 0,08891687 ! grooming behavior GO:0007625 6 5 0,000 0,01022744 0,08860156 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01022744 0,08828848 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01022744 0,0879776 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01022744 0,08766891 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01022744 0,08736238 ! response to protozoan GO:0001562 13 5 0,000 0,01022744 0,08705798 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01022744 0,08675569 ! lymph vessel development GO:0001945 10 5 0,000 0,01022744 0,0864555 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01022744 0,08615738 ! endochondral ossification GO:0001958 17 5 0,000 0,01022744 0,0858613 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01022744 0,08556726 ! single strand break repair GO:0000012 8 5 0,000 0,01022744 0,08527522 ! parathyroid gland development GO:0060017 14 5 0,000 0,01022744 0,08498517 ! anagen GO:0042640 7 5 0,000 0,01022744 0,08469708 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01022744 0,08441094 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01022744 0,08412673 ! cytokine secretion GO:0050663 15 5 0,000 0,01022744 0,08384443 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01022744 0,08356401 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01022744 0,08328546 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01022744 0,08300877 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01022744 0,08273391 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01022744 0,08246086 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01022744 0,0821896 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01022744 0,08192013 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01022744 0,08165242 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01022744 0,08138645 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01022744 0,08112221 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01022744 0,08085967 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01022744 0,08059884 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01022744 0,08033968 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01022744 0,08008218 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01022744 0,07982632 ! microvillus organization GO:0032528 8 5 0,000 0,01022744 0,0795721 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01022744 0,07931949 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01022744 0,07906848 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01022744 0,07881905 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01022744 0,07857119 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01022744 0,07832489 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01022744 0,07808012 ! polyol catabolic process GO:0046174 9 5 0,000 0,01022744 0,07783688 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01022744 0,07759515 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01022744 0,07735492 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01022744 0,07711617 ! muscle cell migration GO:0014812 8 5 0,000 0,01022744 0,07687889 ! mitochondrial fission GO:0000266 8 5 0,000 0,01022744 0,07664307 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01022744 0,07640868 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01022744 0,07617573 ! mRNA transcription GO:0009299 10 5 0,000 0,01022744 0,07594419 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01022744 0,07571406 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01022744 0,07548532 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01022744 0,07525795 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01022744 0,07503195 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01022744 0,0748073 ! monocyte activation GO:0042117 10 5 0,000 0,01022744 0,074584 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01022744 0,07436202 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01022744 0,07414136 ! response to food GO:0032094 6 5 0,000 0,01022744 0,07392201 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01022744 0,07370395 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01022744 0,07348717 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01022744 0,07327167 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01022744 0,07305743 ! forebrain neuron development GO:0021884 13 5 0,000 0,01022744 0,07284443 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01022744 0,07263267 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01022744 0,07242214 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01022744 0,07221283 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01022744 0,07200472 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01022744 0,07179781 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01022744 0,07159209 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01022744 0,07138754 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01022744 0,07118416 ! lipid glycosylation GO:0030259 7 5 0,000 0,01022744 0,07098193 ! nucleobase transport GO:0015851 6 5 0,000 0,01022744 0,07078085 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01022744 0,0705809 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01022744 0,07038208 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01022744 0,07018438 ! basic amino acid transport GO:0015802 12 5 0,000 0,01022744 0,06998779 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01022744 0,06979229 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01022744 0,06959788 ! actin nucleation GO:0045010 11 5 0,000 0,01022744 0,06940455 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01022744 0,0692123 ! depurination GO:0045007 5 5 0,000 0,01022744 0,0690211 ! depyrimidination GO:0045008 10 5 0,000 0,01022744 0,06883096 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01022744 0,06864187 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01022744 0,06845381 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01022744 0,06826677 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01022744 0,06808076 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01022744 0,06789576 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01022744 0,06771176 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01022744 0,06752876 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01022744 0,06734674 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01022744 0,0671657 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01022744 0,06698563 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01022744 0,06680652 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01022744 0,06662837 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01022744 0,06645117 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01022744 0,06627491 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01022744 0,06609958 ! response to arsenic GO:0046685 11 5 0,000 0,01022744 0,06592517 ! mast cell degranulation GO:0043303 7 5 0,000 0,01022744 0,06575168 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01022744 0,06557911 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01022744 0,06540743 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01022744 0,06523666 ! response to mercury ion GO:0046689 8 5 0,000 0,01022744 0,06506677 ! response to cadmium ion GO:0046686 7 5 0,000 0,01022744 0,06489776 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01022744 0,06472964 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01022744 0,06456238 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01022744 0,06439598 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01022744 0,06423044 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01022744 0,06406574 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01022744 0,06390189 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01022744 0,06373888 ! decidualization GO:0046697 11 5 0,000 0,01022744 0,06357669 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01022744 0,06341533 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01022744 0,06325478 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01022744 0,06309505 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01022744 0,06293612 ! embryonic cleavage GO:0040016 6 5 0,000 0,01022744 0,06277799 ! peroxisome fission GO:0016559 5 5 0,000 0,01022744 0,06262065 ! histone demethylation GO:0016577 13 5 0,000 0,01022744 0,0624641 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01022744 0,06230833 ! mitotic recombination GO:0006312 9 5 0,000 0,01022744 0,06215333 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01022744 0,06199911 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01022744 0,06184564 ! metaphase plate congression GO:0051310 7 5 0,000 0,01022744 0,06169294 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01022744 0,06154098 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01022744 0,06138978 ! enteric nervous system development GO:0048484 8 5 0,000 0,01022744 0,06123931 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01022744 0,06108958 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01022744 0,06094058 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01022744 0,06079231 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01022744 0,06064476 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01022744 0,06049792 ! B cell homeostasis GO:0001782 13 5 0,000 0,01022744 0,06035179 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01022744 0,06020636 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01022744 0,06006163 ! metaphase GO:0051323 11 5 0,000 0,01022744 0,0599176 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01022744 0,05977426 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01022744 0,0596316 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01022744 0,05948962 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01022744 0,05934831 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01022744 0,05920768 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01022744 0,05906771 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01022744 0,05892839 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01022744 0,05878974 ! response to redox state GO:0051775 6 5 0,000 0,01022744 0,05865174 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01022744 0,05851438 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01022744 0,05837766 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01022744 0,05824158 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01022744 0,05810614 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01022744 0,05797132 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01022744 0,05783713 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01022744 0,05770356 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01022744 0,0575706 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01022744 0,05743825 ! striatum development GO:0021756 14 5 0,000 0,01022744 0,05730651 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01022744 0,05717538 ! glial cell migration GO:0008347 10 5 0,000 0,01022744 0,05704484 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01022744 0,0569149 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01022744 0,05678554 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01022744 0,05665678 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01022744 0,0565286 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01022744 0,05640099 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01022744 0,05627396 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01022744 0,0561475 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01022744 0,05602161 ! neuroprotection GO:0043526 8 5 0,000 0,01022744 0,05589629 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01022744 0,05577152 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01022744 0,0556473 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01022744 0,05552364 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01022744 0,05540053 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01022744 0,05527796 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01022744 0,05515594 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01022744 0,05503445 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01022744 0,05491349 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01022744 0,05479307 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01022744 0,05467317 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01022744 0,0545538 ! spindle assembly GO:0051225 6 5 0,000 0,01022744 0,05443494 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01022744 0,05431661 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01022744 0,05419878 ! protein palmitoylation GO:0018345 12 5 0,000 0,01022744 0,05408147 ! drug metabolic process GO:0017144 7 5 0,000 0,01022744 0,05396466 ! stem cell division GO:0017145 11 5 0,000 0,01022744 0,05384836 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01022744 0,05373256 ! organ regeneration GO:0031100 7 5 0,000 0,01022744 0,05361725 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01022744 0,05350244 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01022744 0,05338812 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 0,01074933 0,0559928 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,01074933 0,05587367 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01102145 0,05716644 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01102145 0,05704533 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 0,01102145 0,05692472 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01129659 0,05822271 ! response to hypoxia GO:0001666 178 81 1,000 0,01214005 0,06243819 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01214005 0,06230702 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01226051 0,06279337 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01226051 0,062662 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01226051 0,06253119 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01226051 0,06240091 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01226051 0,06227118 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01226051 0,06214199 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01226051 0,06201333 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01226051 0,0618852 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01226051 0,0617576 ! response to oxygen radical GO:0000305 11 6 0,000 0,01226051 0,06163053 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01226051 0,06150398 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01226051 0,06137795 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01226051 0,06125243 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01226051 0,06112742 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01226051 0,06100293 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01226051 0,06087894 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01226051 0,06075545 ! forebrain regionalization GO:0021871 9 6 0,000 0,01226051 0,06063247 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01226051 0,06050998 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01226051 0,06038798 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01226051 0,06026647 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01226051 0,06014546 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01226051 0,06002493 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01226051 0,05990488 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01226051 0,05978531 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01226051 0,05966621 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01226051 0,05954759 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01226051 0,05942944 ! malate metabolic process GO:0006108 13 6 0,000 0,01226051 0,05931176 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01226051 0,05919454 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01226051 0,05907779 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01226051 0,05896149 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01226051 0,05884565 ! protein refolding GO:0042026 15 6 0,000 0,01226051 0,05873027 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01226051 0,05861534 ! opsonization GO:0008228 8 6 0,000 0,01226051 0,05850086 ! mating behavior GO:0007617 7 6 0,000 0,01226051 0,05838682 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01226051 0,05827323 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01226051 0,05816007 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01226051 0,05804736 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01226051 0,05793508 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01226051 0,05782324 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01226051 0,05771183 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01226051 0,05760084 ! toxin metabolic process GO:0009404 11 6 0,000 0,01226051 0,05749028 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01226051 0,05738015 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01226051 0,05727044 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01226051 0,05716114 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01226051 0,05705226 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01226051 0,0569438 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01226051 0,05683575 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01226051 0,0567281 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01226051 0,05662087 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01226051 0,05651403 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01226051 0,0564076 ! protein lipoylation GO:0009249 10 6 0,000 0,01226051 0,05630157 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01226051 0,05619594 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01226051 0,05609071 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01226051 0,05598587 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01226051 0,05588141 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01226051 0,05577735 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01226051 0,05567368 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01226051 0,05557039 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01226051 0,05546748 ! hyperosmotic response GO:0006972 10 6 0,000 0,01226051 0,05536495 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01226051 0,0552628 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01226051 0,05516103 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01226051 0,05505963 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01226051 0,0549586 ! urea metabolic process GO:0019627 7 6 0,000 0,01226051 0,05485794 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01226051 0,05475766 ! neutrophil activation GO:0042119 7 6 0,000 0,01226051 0,05465773 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01226051 0,05455817 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01226051 0,05445898 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01226051 0,05436014 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01226051 0,05426166 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01226051 0,05416354 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01226051 0,05406577 ! neuron apoptosis GO:0051402 15 6 0,000 0,01226051 0,05396836 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01226051 0,05387129 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01226051 0,05377457 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01226051 0,0536782 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01226051 0,05358218 ! carnitine transport GO:0015879 10 6 0,000 0,01226051 0,0534865 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01226051 0,05339115 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01226051 0,05329615 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01226051 0,05320149 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01226051 0,05310716 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01226051 0,05301316 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01226051 0,0529195 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01226051 0,05282617 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01226051 0,05273317 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01226051 0,05264049 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01226051 0,05254814 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01226051 0,05245611 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01226051 0,0523644 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01226051 0,05227302 ! response to UV-C GO:0010225 14 6 0,000 0,01226051 0,05218195 ! astrocyte development GO:0014002 16 6 0,000 0,01226051 0,0520912 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01226051 0,05200076 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01226051 0,05191064 ! interaction with symbiont GO:0051702 14 6 0,000 0,01226051 0,05182083 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01226051 0,05173133 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01226051 0,05164213 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01226051 0,05155325 ! response to copper ion GO:0046688 10 6 0,000 0,01226051 0,05146467 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01226051 0,05137639 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01226051 0,05128842 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01226051 0,05120075 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01226051 0,05111338 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01226051 0,0510263 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01226051 0,05093952 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01226051 0,05085304 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01226051 0,05076684 ! hair follicle maturation GO:0048820 8 6 0,000 0,01226051 0,05068094 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01226051 0,05059533 ! Schwann cell development GO:0014044 15 6 0,000 0,01226051 0,05051001 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01226051 0,05042498 ! response to pheromone GO:0019236 6 6 0,000 0,01226051 0,05034023 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01226051 0,05025577 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01226051 0,05017159 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01226051 0,05008769 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01226051 0,05000407 ! subpallium development GO:0021544 15 6 0,000 0,01226051 0,04992073 ! neural tube patterning GO:0021532 8 6 0,000 0,01226051 0,04983767 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01226051 0,04975488 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01226051 0,04967237 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01226051 0,04959013 ! G2 phase GO:0051319 16 6 0,000 0,01226051 0,04950816 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01226051 0,04942647 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01226051 0,04934504 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01226051 0,04926388 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01226051 0,04918299 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01226051 0,04910236 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01226051 0,04902199 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01226051 0,04894189 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01226051 0,04886205 ! receptor internalization GO:0031623 11 6 0,000 0,01226051 0,04878247 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01226051 0,04870315 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01226051 0,04862409 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01226051 0,04854528 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01226051 0,04846673 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01226051 0,04838843 ! protein deubiquitination GO:0016579 16 6 0,000 0,01226051 0,04831038 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01226051 0,04823259 ! protein destabilization GO:0031648 9 6 0,000 0,01226051 0,04815504 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01226051 0,04807775 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01226051 0,0480007 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01226051 0,0479239 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01226051 0,04784734 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01226051 0,04777103 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01226051 0,04769496 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01226051 0,04761914 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01226051 0,04754355 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01226051 0,04746821 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01226051 0,0473931 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01226051 0,04731823 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01226051 0,04724359 ! neural plate development GO:0001840 9 6 0,000 0,01226051 0,04716919 ! catecholamine transport GO:0051937 9 6 0,000 0,01226051 0,04709503 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01226051 0,0470211 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01226051 0,04694739 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01226051 0,04687392 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01226051 0,04680068 ! maternal placenta development GO:0001893 12 6 0,000 0,01226051 0,04672767 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01226051 0,04665489 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01226051 0,04658233 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01226051 0,04651 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01226051 0,04643789 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01226051 0,046366 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01226051 0,04629434 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01226051 0,0462229 GO:0055081|anion homeostasis, ! response to oxygen levels GO:0070482 183 83 1,000 0,01271726 0,04787097 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01271726 0,04779733 GO:0045937|positive regulation of phosphate metabolic process, ! T cell activation GO:0042110 189 84 1,000 0,01301029 0,04882358 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,01330627 0,04985768 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01330627 0,04978133 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01360516 0,05082173 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,01390697 0,05186981 GO:0070201|regulation of establishment of protein localization, ! tRNA transcription GO:0009304 17 7 0,000 0,01428947 0,0532152 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01428947 0,05313421 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01428947 0,05305346 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01428947 0,05297295 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01428947 0,05289269 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01428947 0,05281267 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01428947 0,05273289 ! sleep GO:0030431 16 7 0,000 0,01428947 0,05265335 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01428947 0,05257406 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01428947 0,052495 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01428947 0,05241618 ! prostate gland development GO:0030850 14 7 0,000 0,01428947 0,05233759 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01428947 0,05225924 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01428947 0,05218113 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01428947 0,05210324 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01428947 0,05202559 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01428947 0,05194817 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01428947 0,05187099 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01428947 0,05179403 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01428947 0,05171729 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01428947 0,05164079 ! glycolipid transport GO:0046836 11 7 0,000 0,01428947 0,05156451 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01428947 0,05148846 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01428947 0,05141263 ! neuron adhesion GO:0007158 14 7 0,000 0,01428947 0,05133702 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01428947 0,05126164 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01428947 0,05118647 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01428947 0,05111153 ! mRNA stabilization GO:0048255 18 7 0,000 0,01428947 0,0510368 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01428947 0,0509623 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01428947 0,05088801 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01428947 0,05081394 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01428947 0,05074008 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01428947 0,05066643 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01428947 0,05059301 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01428947 0,05051979 ! lipoprotein transport GO:0042953 14 7 0,000 0,01428947 0,05044678 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01428947 0,05037399 ! rhythmic behavior GO:0007622 17 7 0,000 0,01428947 0,0503014 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01428947 0,05022903 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01428947 0,05015686 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01428947 0,0500849 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01428947 0,05001314 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01428947 0,04994159 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01428947 0,04987025 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01428947 0,04979911 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01428947 0,04972817 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01428947 0,04965743 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01428947 0,04958689 ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01428947 0,04951656 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01428947 0,04944642 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01428947 0,04937648 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01428947 0,04930674 ! spinal cord patterning GO:0021511 14 7 0,000 0,01428947 0,0492372 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01428947 0,04916785 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01428947 0,0490987 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01428947 0,04902974 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01428947 0,04896097 ! adrenal gland development GO:0030325 17 7 0,000 0,01428947 0,0488924 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01428947 0,04882402 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01428947 0,04875583 ! ovulation GO:0030728 10 7 0,000 0,01428947 0,04868783 ! adenohypophysis development GO:0021984 11 7 0,000 0,01428947 0,04862002 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01428947 0,0485524 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01428947 0,04848496 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01428947 0,04841772 ! microtubule nucleation GO:0007020 21 7 0,000 0,01428947 0,04835066 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01428947 0,04828378 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01428947 0,04821709 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01428947 0,04815058 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01428947 0,04808426 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01428947 0,04801812 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01428947 0,04795216 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01428947 0,04788638 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01428947 0,04782079 ! galactose metabolic process GO:0006012 13 7 0,000 0,01428947 0,04775537 ! response to dietary excess GO:0002021 8 7 0,000 0,01428947 0,04769013 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01428947 0,04762507 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01428947 0,04756018 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01428947 0,04749547 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01428947 0,04743094 ! organ growth GO:0035265 15 7 0,000 0,01428947 0,04736659 ! nucleoside transport GO:0015858 11 7 0,000 0,01428947 0,0473024 ! nucleoside salvage GO:0043174 11 7 0,000 0,01428947 0,04723839 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01428947 0,04717456 ! male sex determination GO:0030238 15 7 0,000 0,01428947 0,0471109 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01428947 0,0470474 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01428947 0,04698408 ! parturition GO:0007567 16 7 0,000 0,01428947 0,04692093 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01428947 0,04685795 ! rRNA modification GO:0000154 14 7 0,000 0,01428947 0,04679514 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01428947 0,04673249 ! spindle checkpoint GO:0031577 16 7 0,000 0,01428947 0,04667002 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01428947 0,04660771 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01428947 0,04654556 ! monocyte differentiation GO:0030224 16 7 0,000 0,01428947 0,04648359 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01428947 0,04642177 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01428947 0,04636012 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01428947 0,04629864 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01428947 0,04623732 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01428947 0,04617616 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01428947 0,04611516 ! fibrinolysis GO:0042730 11 7 0,000 0,01428947 0,04605432 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01428947 0,04599364 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01428947 0,04593312 ! eating behavior GO:0042755 8 7 0,000 0,01428947 0,04587276 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01428947 0,04581256 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01428947 0,04575252 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01428947 0,04569264 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01428947 0,04563291 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01428947 0,04557333 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01428947 0,04551392 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01428947 0,04545465 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01428947 0,04539554 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01428947 0,04533659 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01428947 0,04527779 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01428947 0,04521914 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01428947 0,04516064 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01428947 0,04510229 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01428947 0,04504409 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01428947 0,04498605 ! histone ubiquitination GO:0016574 9 7 0,000 0,01428947 0,04492815 ! regulation of meiosis GO:0040020 12 7 0,000 0,01428947 0,0448704 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01428947 0,0448128 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01428947 0,04475535 ! regulation of lipid transport GO:0032368 14 7 0,000 0,01428947 0,04469805 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01428947 0,04464089 ! transcription termination GO:0006353 14 7 0,000 0,01428947 0,04458387 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01428947 0,04452701 ! anaphase GO:0051322 18 7 0,000 0,01428947 0,04447028 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01428947 0,04441371 ! axonal fasciculation GO:0007413 19 7 0,000 0,01428947 0,04435727 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01428947 0,04430098 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01428947 0,04424483 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01428947 0,04418883 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01428947 0,04413296 ! diuresis GO:0030146 12 7 0,000 0,01428947 0,04407724 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01428947 0,04402166 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01428947 0,04396621 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01428947 0,04391091 ! antibiotic transport GO:0042891 9 7 0,000 0,01428947 0,04385575 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01428947 0,04380072 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01428947 0,04374583 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01428947 0,04369108 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01428947 0,04363647 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01428947 0,04358199 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01428947 0,04352765 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01428947 0,04347344 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01428947 0,04341937 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01428947 0,04336543 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01428947 0,04331163 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01428947 0,04325796 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01428947 0,04320442 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01428947 0,04315102 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01428947 0,04309775 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01428947 0,0430446 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01428947 0,04299159 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01428947 0,04293871 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01428947 0,04288596 ! muscle adaptation GO:0043500 13 7 0,000 0,01428947 0,04283334 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01428947 0,04278085 ! retina homeostasis GO:0001895 12 7 0,000 0,01428947 0,04272849 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01428947 0,04267625 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01428947 0,04262414 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01428947 0,04257216 ! tube morphogenesis GO:0035239 194 89 1,000 0,01451927 0,0432041 ! ossification GO:0001503 205 91 1,000 0,01514305 0,04500544 ! gland development GO:0048732 220 91 1,000 0,01514305 0,04495075 ! bone development GO:0060348 206 92 1,000 0,01545922 0,04583358 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,01577822 0,04672266 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01610005 0,04761794 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01631431 0,04819331 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01631431 0,0481351 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01631431 0,04807704 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01631431 0,04801912 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01631431 0,04796133 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01631431 0,04790369 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01631431 0,04784618 ! male meiosis GO:0007140 9 8 0,000 0,01631431 0,04778881 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01631431 0,04773158 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01631431 0,04767448 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01631431 0,04761752 ! meiotic prophase I GO:0007128 14 8 0,000 0,01631431 0,0475607 ! response to zinc ion GO:0010043 12 8 0,000 0,01631431 0,04750401 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01631431 0,04744746 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01631431 0,04739104 ! oligopeptide transport GO:0006857 16 8 0,000 0,01631431 0,04733476 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01631431 0,04727861 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01631431 0,04722259 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01631431 0,04716671 ! signal peptide processing GO:0006465 12 8 0,000 0,01631431 0,04711095 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01631431 0,04705533 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01631431 0,04699984 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01631431 0,04694448 ! succinate metabolic process GO:0006105 17 8 0,000 0,01631431 0,04688925 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01631431 0,04683416 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01631431 0,04677919 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01631431 0,04672435 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01631431 0,04666963 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01631431 0,04661505 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01631431 0,04656059 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01631431 0,04650626 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01631431 0,04645206 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01631431 0,04639798 ! reflex GO:0060004 17 8 0,000 0,01631431 0,04634403 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01631431 0,04629021 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01631431 0,0462365 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01631431 0,04618293 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01631431 0,04612948 ! pigment granule organization GO:0048753 17 8 0,000 0,01631431 0,04607615 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01631431 0,04602294 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01631431 0,04596986 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01631431 0,0459169 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01631431 0,04586406 ! histidine catabolic process GO:0006548 10 8 0,000 0,01631431 0,04581134 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01631431 0,04575874 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01631431 0,04570627 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01631431 0,04565391 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01631431 0,04560168 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01631431 0,04554956 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01631431 0,04549756 ! melanin metabolic process GO:0006582 17 8 0,000 0,01631431 0,04544569 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01631431 0,04539393 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01631431 0,04534228 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01631431 0,04529076 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01631431 0,04523935 ! macrophage activation GO:0042116 13 8 0,000 0,01631431 0,04518806 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01631431 0,04513688 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01631431 0,04508582 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01631431 0,04503488 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01631431 0,04498405 ! purine salvage GO:0043101 12 8 0,000 0,01631431 0,04493333 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01631431 0,04488273 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01631431 0,04483225 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01631431 0,04478187 ! osteoblast development GO:0002076 17 8 0,000 0,01631431 0,04473161 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01631431 0,04468146 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01631431 0,04463143 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01631431 0,04458151 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01631431 0,04453169 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01631431 0,04448199 ! response to UV-B GO:0010224 17 8 0,000 0,01631431 0,0444324 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01631431 0,04438292 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01631431 0,04433356 ! intermediate filament organization GO:0045109 12 8 0,000 0,01631431 0,0442843 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01631431 0,04423515 ! cellular extravasation GO:0045123 13 8 0,000 0,01631431 0,0441861 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01631431 0,04413717 ! response to antibiotic GO:0046677 11 8 0,000 0,01631431 0,04408835 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01631431 0,04403963 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01631431 0,04399102 ! DNA topological change GO:0006265 12 8 0,000 0,01631431 0,04394252 ! response to tropane GO:0014073 15 8 0,000 0,01631431 0,04389413 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01631431 0,04384584 ! melanosome transport GO:0032402 13 8 0,000 0,01631431 0,04379766 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01631431 0,04374958 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01631431 0,04370161 ! mast cell activation GO:0045576 14 8 0,000 0,01631431 0,04365374 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01631431 0,04360598 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01631431 0,04355832 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01631431 0,04351077 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01631431 0,04346332 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01631431 0,04341598 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01631431 0,04336873 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01631431 0,04332159 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01631431 0,04327456 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01631431 0,04322762 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01631431 0,04318079 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01631431 0,04313405 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01631431 0,04308742 ! response to tumor cell GO:0002347 16 8 0,000 0,01631431 0,04304089 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01631431 0,04299446 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01631431 0,04294813 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01631431 0,0429019 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01631431 0,04285577 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01631431 0,04280974 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01631431 0,04276381 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01631431 0,04271797 ! hormone catabolic process GO:0042447 17 8 0,000 0,01631431 0,04267223 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01631431 0,0426266 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01631431 0,04258105 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01631431 0,04253561 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01631431 0,04249026 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01631431 0,04244501 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01631431 0,04239986 ! adult feeding behavior GO:0008343 10 8 0,000 0,01631431 0,0423548 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01631431 0,04230984 ! ATP catabolic process GO:0006200 11 8 0,000 0,01631431 0,04226497 ! blastocyst growth GO:0001832 19 8 0,000 0,01631431 0,0422202 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01631431 0,04217552 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01631431 0,04213094 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01631431 0,04208645 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01631431 0,04204205 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01631431 0,04199775 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01631431 0,04195354 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01631431 0,04190943 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01631431 0,04186541 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01631431 0,04182148 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01631431 0,04177764 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01631431 0,04173389 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01631431 0,04169024 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01631431 0,04164667 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01631431 0,0416032 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01631431 0,04155982 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01631431 0,04151653 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01642468 0,0417539 ! sex differentiation GO:0007548 171 96 1,000 0,01675211 0,04254201 ! regulation of T cell activation GO:0050863 175 96 1,000 0,01675211 0,04249783 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,01708233 0,04329058 ! regulation of protein localization GO:0032880 188 97 1,000 0,01708233 0,04324572 ! leukocyte differentiation GO:0002521 232 98 1,000 0,01741531 0,04404307 ! interphase of mitotic cell cycle GO:0051329 224 98 1,000 0,01741531 0,04399753 ! forebrain development GO:0030900 210 98 1,000 0,01741531 0,04395207 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,01808955 0,04560657 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,01808955 0,04555955 ! axon extension GO:0048675 16 9 0,000 0,01833505 0,04613032 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01833505 0,04608286 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01833505 0,0460355 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01833505 0,04598823 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01833505 0,04594106 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01833505 0,04589399 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01833505 0,04584702 ! reproductive behavior GO:0019098 22 9 0,000 0,01833505 0,04580014 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01833505 0,04575336 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01833505 0,04570667 ! UTP metabolic process GO:0046051 10 9 0,000 0,01833505 0,04566008 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01833505 0,04561358 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01833505 0,04556718 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01833505 0,04552087 ! artery development GO:0060840 25 9 0,000 0,01833505 0,04547466 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01833505 0,04542854 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01833505 0,04538251 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01833505 0,04533658 ! equilibrioception GO:0050957 20 9 0,000 0,01833505 0,04529074 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01833505 0,04524499 ! chemosensory behavior GO:0007635 21 9 0,000 0,01833505 0,04519933 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01833505 0,04515377 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01833505 0,0451083 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01833505 0,04506291 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01833505 0,04501763 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01833505 0,04497243 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01833505 0,04492732 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01833505 0,0448823 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01833505 0,04483737 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01833505 0,04479254 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01833505 0,04474779 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01833505 0,04470313 ! protein targeting to ER GO:0045047 25 9 0,000 0,01833505 0,04465856 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01833505 0,04461408 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01833505 0,04456969 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01833505 0,04452538 ! glycine catabolic process GO:0006546 15 9 0,000 0,01833505 0,04448117 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01833505 0,04443704 ! endosome organization GO:0007032 20 9 0,000 0,01833505 0,044393 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01833505 0,04434905 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01833505 0,04430518 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01833505 0,0442614 ! mannose metabolic process GO:0006013 13 9 0,000 0,01833505 0,04421771 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01833505 0,0441741 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01833505 0,04413058 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01833505 0,04408714 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01833505 0,04404379 ! receptor clustering GO:0043113 20 9 0,000 0,01833505 0,04400053 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01833505 0,04395735 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01833505 0,04391425 ! retinol metabolic process GO:0042572 20 9 0,000 0,01833505 0,04387124 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01833505 0,04382831 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01833505 0,04378547 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01833505 0,04374271 ! macrophage differentiation GO:0030225 15 9 0,000 0,01833505 0,04370004 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01833505 0,04365744 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01833505 0,04361493 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01833505 0,04357251 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01833505 0,04353016 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01833505 0,0434879 ! response to amine stimulus GO:0014075 13 9 0,000 0,01833505 0,04344572 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01833505 0,04340362 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01833505 0,0433616 ! erythrocyte development GO:0048821 17 9 0,000 0,01833505 0,04331967 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01833505 0,04327781 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01833505 0,04323604 ! renal water homeostasis GO:0003091 15 9 0,000 0,01833505 0,04319435 ! postreplication repair GO:0006301 25 9 0,000 0,01833505 0,04315273 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01833505 0,0431112 ! icosanoid secretion GO:0032309 15 9 0,000 0,01833505 0,04306975 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01833505 0,04302837 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01833505 0,04298708 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01833505 0,04294586 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01833505 0,04290473 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01833505 0,04286367 ! sterol catabolic process GO:0016127 14 9 0,000 0,01833505 0,04282269 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01833505 0,04278179 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01833505 0,04274097 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01833505 0,04270023 ! S phase GO:0051320 10 9 0,000 0,01833505 0,04265956 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01833505 0,04261897 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01833505 0,04257846 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01833505 0,04253802 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01833505 0,04249766 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01833505 0,04245738 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01833505 0,04241718 ! purine base metabolic process GO:0006144 25 9 0,000 0,01833505 0,04237705 ! pigment granule transport GO:0051904 17 9 0,000 0,01833505 0,04233699 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01833505 0,04229701 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01833505 0,04225711 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01833505 0,04221728 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01833505 0,04217753 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01833505 0,04213785 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01833505 0,04209825 ! mitochondrion localization GO:0051646 18 9 0,000 0,01833505 0,04205872 ! regulation of developmental growth GO:0048638 16 10 0,000 0,0203517 0,04664091 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,0203517 0,04659719 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0203517 0,04655356 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0203517 0,04651001 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0203517 0,04646655 ! associative learning GO:0008306 21 10 0,000 0,0203517 0,04642316 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0203517 0,04637986 ! phosphate transport GO:0006817 24 10 0,000 0,0203517 0,04633663 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0203517 0,04629349 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0203517 0,04625042 ! CTP metabolic process GO:0046036 11 10 0,000 0,0203517 0,04620744 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0203517 0,04616454 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0203517 0,04612171 ! GTP metabolic process GO:0046039 11 10 0,000 0,0203517 0,04607897 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0203517 0,0460363 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0203517 0,04599371 ! social behavior GO:0035176 29 10 0,000 0,0203517 0,04595121 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0203517 0,04590878 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0203517 0,04586643 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0203517 0,04582415 ! androgen metabolic process GO:0008209 17 10 0,000 0,0203517 0,04578196 ! phospholipid efflux GO:0033700 19 10 0,000 0,0203517 0,04573984 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0203517 0,0456978 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0203517 0,04565584 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0203517 0,04561395 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0203517 0,04557214 ! lung alveolus development GO:0048286 26 10 0,000 0,0203517 0,04553041 ! pathogenesis GO:0009405 17 10 0,000 0,0203517 0,04548875 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0203517 0,04544717 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0203517 0,04540567 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0203517 0,04536424 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0203517 0,04532289 ! endoderm development GO:0007492 18 10 0,000 0,0203517 0,04528161 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0203517 0,0452404 ! arginine catabolic process GO:0006527 17 10 0,000 0,0203517 0,04519928 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0203517 0,04515822 ! proline metabolic process GO:0006560 13 10 0,000 0,0203517 0,04511725 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0203517 0,04507634 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0203517 0,04503551 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0203517 0,04499476 ! V(D)J recombination GO:0033151 34 10 0,000 0,0203517 0,04495407 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0203517 0,04491346 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0203517 0,04487293 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0203517 0,04483247 ! B cell proliferation GO:0042100 19 10 0,000 0,0203517 0,04479208 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0203517 0,04475176 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0203517 0,04471152 ! multicellular organism growth GO:0035264 19 10 0,000 0,0203517 0,04467134 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0203517 0,04463124 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0203517 0,04459122 ! ruffle organization GO:0031529 17 10 0,000 0,0203517 0,04455126 ! epithelial cell development GO:0002064 21 10 0,000 0,0203517 0,04451137 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0203517 0,04447156 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0203517 0,04443182 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0203517 0,04439215 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0203517 0,04435255 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0203517 0,04431302 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0203517 0,04427356 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0203517 0,04423417 ! motor axon guidance GO:0008045 22 10 0,000 0,0203517 0,04419485 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0203517 0,0441556 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0203517 0,04411642 ! protein heterooligomerization GO:0051291 17 10 0,000 0,0203517 0,04407731 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0203517 0,04403827 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0203517 0,0439993 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0203517 0,04396039 ! segment specification GO:0007379 15 10 0,000 0,0203517 0,04392156 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0203517 0,04388279 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0203517 0,0438441 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0203517 0,04380547 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0203517 0,04376691 ! response to dsRNA GO:0043331 23 10 0,000 0,0203517 0,04372841 ! DNA ligation GO:0006266 18 10 0,000 0,0203517 0,04368999 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0203517 0,04365163 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0203517 0,04361334 ! melanosome localization GO:0032400 16 10 0,000 0,0203517 0,04357511 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0203517 0,04353696 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0203517 0,04349887 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0203517 0,04346084 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0203517 0,04342289 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0203517 0,043385 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0203517 0,04334717 ! protein sumoylation GO:0016925 17 10 0,000 0,0203517 0,04330941 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0203517 0,04327172 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0203517 0,04323409 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0203517 0,04319653 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0203517 0,04315903 ! salivary gland development GO:0007431 28 10 0,000 0,0203517 0,0431216 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0203517 0,04308423 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0203517 0,04304693 ! midbrain development GO:0030901 14 10 0,000 0,0203517 0,04300969 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0203517 0,04297252 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0203517 0,04293541 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0203517 0,04289836 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0203517 0,04286138 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0203517 0,04282447 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0203517 0,04278761 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0203517 0,04275082 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0203517 0,04271409 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0203517 0,04267743 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,0203517 0,04264083 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,0203517 0,04260429 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0203517 0,04256781 ! blastocyst formation GO:0001825 18 10 0,000 0,0203517 0,0425314 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0203517 0,04249505 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0203517 0,04245876 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0203517 0,04242253 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0203517 0,04238636 ! response to nicotine GO:0035094 20 10 0,000 0,0203517 0,04235026 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0203517 0,04231422 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02236426 0,04645909 ! respiratory burst GO:0045730 17 11 0,000 0,02236426 0,04641962 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02236426 0,04638021 ! neuron fate specification GO:0048665 18 11 0,000 0,02236426 0,04634087 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02236426 0,0463016 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02236426 0,0462624 ! thyroid gland development GO:0030878 26 11 0,000 0,02236426 0,04622326 ! synapsis GO:0007129 14 11 0,000 0,02236426 0,04618418 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02236426 0,04614518 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02236426 0,04610624 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02236426 0,04606736 ! response to pain GO:0048265 27 11 0,000 0,02236426 0,04602855 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02236426 0,04598981 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02236426 0,04595113 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02236426 0,04591251 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02236426 0,04587396 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02236426 0,04583548 ! bone resorption GO:0045453 16 11 0,000 0,02236426 0,04579706 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02236426 0,0457587 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02236426 0,04572041 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02236426 0,04568218 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02236426 0,04564402 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02236426 0,04560592 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02236426 0,04556788 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02236426 0,04552991 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02236426 0,045492 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02236426 0,04545415 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02236426 0,04541637 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02236426 0,04537865 ! UV protection GO:0009650 20 11 0,000 0,02236426 0,04534099 ! adult heart development GO:0007512 16 11 0,000 0,02236426 0,04530339 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02236426 0,04526586 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02236426 0,04522839 ! macroautophagy GO:0016236 19 11 0,000 0,02236426 0,04519098 ! temperature homeostasis GO:0001659 18 11 0,000 0,02236426 0,04515363 ! behavioral fear response GO:0001662 27 11 0,000 0,02236426 0,04511634 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02236426 0,04507912 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02236426 0,04504195 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02236426 0,04500485 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02236426 0,04496781 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02236426 0,04493083 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02236426 0,04489391 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02236426 0,04485705 ! regulation of organ growth GO:0046620 14 11 0,000 0,02236426 0,04482025 ! pigment granule localization GO:0051875 20 11 0,000 0,02236426 0,04478352 ! vasoconstriction GO:0042310 20 11 0,000 0,02236426 0,04474684 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02236426 0,04471022 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02236426 0,04467366 ! embryonic axis specification GO:0000578 19 11 0,000 0,02236426 0,04463717 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02236426 0,04460073 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02236426 0,04456435 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02236426 0,04452803 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02236426 0,04449177 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02236426 0,04445557 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02236426 0,04441942 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02236426 0,04438334 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02236426 0,04434731 ! prophase GO:0051324 17 11 0,000 0,02236426 0,04431135 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02236426 0,04427544 ! nucleosome positioning GO:0016584 15 11 0,000 0,02236426 0,04423959 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02236426 0,04420379 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02236426 0,04416806 ! apical protein localization GO:0045176 18 11 0,000 0,02236426 0,04413238 ! acid secretion GO:0046717 20 11 0,000 0,02236426 0,04409676 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02236426 0,0440612 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02236426 0,0440257 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02236426 0,04399025 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02236426 0,04395486 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02236426 0,04391953 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02236426 0,04388425 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02236426 0,04384903 ! cholesterol efflux GO:0033344 21 11 0,000 0,02236426 0,04381387 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02236426 0,04377876 ! oocyte development GO:0048599 20 11 0,000 0,02236426 0,04374371 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02236426 0,04370871 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02236426 0,04367377 ! embryonic gut development GO:0048566 19 11 0,000 0,02236426 0,04363889 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02236426 0,04360406 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02236426 0,04356929 ! activation of innate immune response GO:0002218 16 11 0,000 0,02236426 0,04353457 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02236426 0,04349991 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02236426 0,04346531 ! lysogeny GO:0030069 22 11 0,000 0,02236426 0,04343076 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02236426 0,04339626 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02236426 0,04336182 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02236426 0,04332743 ! nucleus localization GO:0051647 22 11 0,000 0,02236426 0,0432931 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02437274 0,0471438 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02437274 0,0471065 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02437274 0,04706926 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02437274 0,04703208 ! virus-host interaction GO:0019048 30 12 0,000 0,02437274 0,04699496 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02437274 0,0469579 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02437274 0,04692089 ! protein complex disassembly GO:0043241 28 12 0,000 0,02437274 0,04688395 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02437274 0,04684706 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02437274 0,04681023 ! hippocampus development GO:0021766 29 12 0,000 0,02437274 0,04677346 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02437274 0,04673674 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02437274 0,04670009 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02437274 0,04666349 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02437274 0,04662695 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02437274 0,04659046 ! drug transport GO:0015893 16 12 0,000 0,02437274 0,04655404 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02437274 0,04651767 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02437274 0,04648135 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02437274 0,0464451 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02437274 0,0464089 ! focal adhesion formation GO:0048041 37 12 0,000 0,02437274 0,04637275 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02437274 0,04633666 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02437274 0,04630063 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02437274 0,04626466 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02437274 0,04622874 ! lipid digestion GO:0044241 21 12 0,000 0,02437274 0,04619287 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02437274 0,04615706 ! entry into host cell GO:0030260 34 12 0,000 0,02437274 0,04612131 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02437274 0,04608561 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02437274 0,04604997 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02437274 0,04601438 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02437274 0,04597885 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02437274 0,04594337 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02437274 0,04590795 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02437274 0,04587258 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02437274 0,04583727 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02437274 0,04580201 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02437274 0,0457668 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02437274 0,04573165 ! cranial nerve development GO:0021545 23 12 0,000 0,02437274 0,04569656 ! fucose catabolic process GO:0019317 25 12 0,000 0,02437274 0,04566151 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02437274 0,04562652 ! histone acetylation GO:0016573 27 12 0,000 0,02437274 0,04559159 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02437274 0,0455567 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02437274 0,04552188 ! zymogen activation GO:0031638 18 12 0,000 0,02437274 0,0454871 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02437274 0,04545238 ! T cell homeostasis GO:0043029 28 12 0,000 0,02437274 0,04541771 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02437274 0,04538309 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02437274 0,04534852 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02437274 0,04531401 ! oocyte differentiation GO:0009994 21 12 0,000 0,02437274 0,04527955 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02437274 0,04524515 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02437274 0,04521079 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02437274 0,04517649 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02437274 0,04514224 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02437274 0,04510804 ! defense response to fungus GO:0050832 15 12 0,000 0,02437274 0,04507389 ! embryonic placenta development GO:0001892 21 12 0,000 0,02437274 0,0450398 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02437274 0,04500575 ! response to cold GO:0009409 17 12 0,000 0,02437274 0,04497176 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02437274 0,04493782 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02437274 0,04490393 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02637716 0,04856021 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02637716 0,04852364 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02637716 0,04848713 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02637716 0,04845067 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02637716 0,04841427 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02637716 0,04837792 ! peroxisomal transport GO:0043574 28 13 0,000 0,02637716 0,04834163 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02637716 0,04830539 ! cartilage condensation GO:0001502 22 13 0,000 0,02637716 0,04826921 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02637716 0,04823308 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02637716 0,048197 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02637716 0,04816098 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02637716 0,04812501 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02637716 0,0480891 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02637716 0,04805324 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02637716 0,04801743 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02637716 0,04798168 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02637716 0,04794598 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02637716 0,04791033 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02637716 0,04787473 ! methionine metabolic process GO:0006555 31 13 0,000 0,02637716 0,04783919 ! plasma membrane organization GO:0007009 27 13 0,000 0,02637716 0,0478037 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02637716 0,04776827 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02637716 0,04773288 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02637716 0,04769755 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02637716 0,04766227 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02637716 0,04762705 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02637716 0,04759187 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02637716 0,04755675 ! exocrine system development GO:0035272 34 13 0,000 0,02637716 0,04752168 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02637716 0,04748666 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02637716 0,04745169 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02637716 0,04741677 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02637716 0,04738191 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02637716 0,04734709 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02637716 0,04731233 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02637716 0,04727762 ! protein homotetramerization GO:0051289 24 13 0,000 0,02637716 0,04724296 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02637716 0,04720835 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02637716 0,04717379 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02637716 0,04713928 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02637716 0,04710482 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02637716 0,04707041 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02637716 0,04703605 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02637716 0,04700175 ! histone methylation GO:0016571 29 13 0,000 0,02637716 0,04696749 ! chromatin silencing GO:0006342 29 13 0,000 0,02637716 0,04693328 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02637716 0,04689912 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02637716 0,04686501 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02637716 0,04683095 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02637716 0,04679694 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02637716 0,04676298 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02637716 0,04672907 ! spleen development GO:0048536 24 13 0,000 0,02637716 0,04669521 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02637716 0,0466614 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02637716 0,04662764 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02637716 0,04659392 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02637716 0,04656026 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02637716 0,04652664 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02637716 0,04649307 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02637716 0,04645955 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02637716 0,04642608 ! insulin secretion GO:0030073 24 13 0,000 0,02637716 0,04639265 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02637716 0,04635928 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02637716 0,04632595 ! acrosome reaction GO:0007340 19 13 0,000 0,02637716 0,04629267 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02637716 0,04625944 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02637716 0,04622625 ! rRNA transcription GO:0009303 28 14 0,000 0,02837751 0,04969624 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02837751 0,04966064 GO:0046579|positive regulation of Ras protein signal transduction, ! water transport GO:0006833 21 14 0,000 0,02837751 0,04962509 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02837751 0,04958959 ! non-recombinational repair GO:0000726 29 14 0,000 0,02837751 0,04955415 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02837751 0,04951875 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02837751 0,0494834 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02837751 0,04944811 ! palate development GO:0060021 32 14 0,000 0,02837751 0,04941287 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02837751 0,04937767 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02837751 0,04934253 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02837751 0,04930743 ! arginine metabolic process GO:0006525 21 14 0,000 0,02837751 0,04927239 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02837751 0,04923739 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02837751 0,04920245 ! regulation of heart rate GO:0002027 25 14 0,000 0,02837751 0,04916755 ! fear response GO:0042596 34 14 0,000 0,02837751 0,04913271 ! organic alcohol transport GO:0015850 29 14 0,000 0,02837751 0,04909791 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02837751 0,04906316 ! embryo implantation GO:0007566 30 14 0,000 0,02837751 0,04902847 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02837751 0,04899382 ! bone mineralization GO:0030282 18 14 0,000 0,02837751 0,04895922 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02837751 0,04892467 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02837751 0,04889016 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02837751 0,04885571 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02837751 0,0488213 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02837751 0,04878695 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02837751 0,04875264 ! ribosome assembly GO:0042255 18 14 0,000 0,02837751 0,04871838 ! cerebellum development GO:0021549 23 14 0,000 0,02837751 0,04868416 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02837751 0,04865 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02837751 0,04861588 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02837751 0,04858182 ! response to gamma radiation GO:0010332 30 14 0,000 0,02837751 0,04854779 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02837751 0,04851382 ! NADP metabolic process GO:0006739 24 14 0,000 0,02837751 0,0484799 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02837751 0,04844602 ! oxygen transport GO:0015671 22 14 0,000 0,02837751 0,04841219 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02837751 0,0483784 ! male genitalia development GO:0030539 26 14 0,000 0,02837751 0,04834467 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02837751 0,04831098 ! regulation of axon extension GO:0030516 43 14 0,000 0,02837751 0,04827733 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02837751 0,04824374 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02837751 0,04821019 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0303738 0,05156581 ! lactation GO:0007595 30 15 0,000 0,0303738 0,05153 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,0303738 0,05149424 ! reproductive cellular process GO:0048610 22 15 0,000 0,0303738 0,05145853 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0303738 0,05142287 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0303738 0,05138726 ! superoxide anion generation GO:0042554 22 15 0,000 0,0303738 0,0513517 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0303738 0,05131619 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0303738 0,05128072 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0303738 0,05124531 ! copper ion transport GO:0006825 22 15 0,000 0,0303738 0,05120994 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0303738 0,05117462 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0303738 0,05113936 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0303738 0,05110414 ! sulfate transport GO:0008272 27 15 0,000 0,0303738 0,05106896 ! response to cAMP GO:0051591 25 15 0,000 0,0303738 0,05103384 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0303738 0,05099877 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0303738 0,05096374 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0303738 0,05092876 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0303738 0,05089383 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0303738 0,05085895 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0303738 0,05082411 ! vesicle coating GO:0006901 38 15 0,000 0,0303738 0,05078933 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0303738 0,05075459 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0303738 0,05071989 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0303738 0,05068525 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0303738 0,05065065 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0303738 0,0506161 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0303738 0,0505816 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0303738 0,05054714 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0303738 0,05051273 ! histone deacetylation GO:0016575 24 15 0,000 0,0303738 0,05047837 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0303738 0,05044405 ! water homeostasis GO:0030104 28 15 0,000 0,0303738 0,05040979 ! cofactor transport GO:0051181 30 15 0,000 0,0303738 0,05037556 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0303738 0,05034139 ! muscle maintenance GO:0046716 26 15 0,000 0,0303738 0,05030726 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0303738 0,05027317 ! intestinal absorption GO:0050892 31 15 0,000 0,0303738 0,05023914 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0303738 0,05020515 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0303738 0,0501712 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0303738 0,0501373 ! cell killing GO:0001906 32 15 0,000 0,0303738 0,05010345 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0303738 0,05006964 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0303738 0,05003588 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0303738 0,05000216 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0303738 0,04996849 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0303738 0,04993486 ! actin filament polymerization GO:0030041 27 15 0,000 0,0303738 0,04990128 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0303738 0,04986775 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03236606 0,05310294 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03236606 0,0530673 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03236606 0,05303171 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03236606 0,05299616 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03236606 0,05296067 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03236606 0,05292522 ! bone remodeling GO:0046849 28 16 0,000 0,03236606 0,05288982 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03236606 0,05285446 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03236606 0,05281916 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03236606 0,0527839 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03236606 0,05274868 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03236606 0,05271352 ! startle response GO:0001964 28 16 0,000 0,03236606 0,0526784 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03236606 0,05264333 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03236606 0,0526083 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03236606 0,05257332 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03236606 0,05253839 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03236606 0,0525035 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03236606 0,05246866 ! pituitary gland development GO:0021983 30 16 0,000 0,03236606 0,05243387 ! response to osmotic stress GO:0006970 27 16 0,000 0,03236606 0,05239912 ! lysosomal transport GO:0007041 31 16 0,000 0,03236606 0,05236442 ! fructose metabolic process GO:0006000 25 16 0,000 0,03236606 0,05232977 ! L-amino acid transport GO:0015807 33 16 0,000 0,03236606 0,05229516 ! stem cell development GO:0048864 46 16 0,000 0,03236606 0,05226059 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03236606 0,05222607 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03236606 0,0521916 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03236606 0,05215717 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03236606 0,05212279 ! axon cargo transport GO:0008088 46 16 0,000 0,03236606 0,05208846 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03236606 0,05205416 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03236606 0,05201992 ! DNA replication initiation GO:0006270 28 16 0,000 0,03236606 0,05198572 ! neuron recognition GO:0008038 40 16 0,000 0,03236606 0,05195156 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03236606 0,05191745 ! tissue regeneration GO:0042246 27 16 0,000 0,03236606 0,05188338 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03236606 0,05184936 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03236606 0,05181538 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03236606 0,05178145 ! biomineral formation GO:0031214 22 16 0,000 0,03236606 0,05174756 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03236606 0,05171372 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03236606 0,05167992 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03236606 0,05164616 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03236606 0,05161245 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03236606 0,05157878 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03236606 0,05154516 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03236606 0,05151158 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03236606 0,05147804 ! peptide hormone processing GO:0016486 27 16 0,000 0,03236606 0,05144455 ! metencephalon development GO:0022037 32 17 0,000 0,03435427 0,05456923 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03435427 0,05453378 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03435427 0,05449837 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03435427 0,054463 ! signal complex assembly GO:0007172 47 17 0,000 0,03435427 0,05442768 ! filopodium assembly GO:0046847 42 17 0,000 0,03435427 0,05439241 ! endothelial cell migration GO:0043542 31 17 0,000 0,03435427 0,05435718 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03435427 0,054322 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03435427 0,05428686 ! glial cell development GO:0021782 28 17 0,000 0,03435427 0,05425177 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03435427 0,05421672 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03435427 0,05418172 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03435427 0,05414676 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03435427 0,05411185 ! myoblast differentiation GO:0045445 50 17 0,000 0,03435427 0,05407699 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03435427 0,05404217 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03435427 0,05400739 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03435427 0,05397266 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03435427 0,05393797 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03435427 0,05390333 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03435427 0,05386873 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03435427 0,05383418 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03435427 0,05379967 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03435427 0,0537652 ! membrane budding GO:0006900 42 17 0,000 0,03435427 0,05373078 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03435427 0,05369641 ! regulation of protein binding GO:0043393 33 17 0,000 0,03435427 0,05366207 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03435427 0,05362778 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03435427 0,05359354 ! genitalia development GO:0048806 32 17 0,000 0,03435427 0,05355934 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03435427 0,05352518 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03435427 0,05349107 ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03435427 0,053457 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03435427 0,05342297 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03435427 0,05338898 ! steroid catabolic process GO:0006706 34 17 0,000 0,03435427 0,05335504 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03435427 0,05332115 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03435427 0,05328729 ! gas transport GO:0015669 26 17 0,000 0,03435427 0,05325348 ! organic cation transport GO:0015695 32 17 0,000 0,03435427 0,05321971 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03435427 0,05318598 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03633846 0,0562222 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03633846 0,05618661 ! limbic system development GO:0021761 40 18 0,000 0,03633846 0,05615107 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03633846 0,05611558 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03633846 0,05608013 ! adult walking behavior GO:0007628 36 18 0,000 0,03633846 0,05604473 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03633846 0,05600937 ! heart looping GO:0001947 34 18 0,000 0,03633846 0,05597405 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03633846 0,05593878 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03633846 0,05590356 ! centrosome cycle GO:0007098 26 18 0,000 0,03633846 0,05586837 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03633846 0,05583324 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03633846 0,05579814 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03633846 0,05576309 ! glycine metabolic process GO:0006544 30 18 0,000 0,03633846 0,05572809 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03633846 0,05569313 ! response to retinoic acid GO:0032526 31 18 0,000 0,03633846 0,05565821 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03633846 0,05562334 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03633846 0,05558851 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03633846 0,05555372 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03633846 0,05551898 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03633846 0,05548428 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03633846 0,05544962 ! neural crest cell migration GO:0001755 41 18 0,000 0,03633846 0,05541501 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03633846 0,05538044 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03633846 0,05534591 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03633846 0,05531143 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03633846 0,05527699 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03633846 0,05524259 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03633846 0,05520824 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03633846 0,05517393 ! detection of bacterium GO:0016045 22 18 0,000 0,03633846 0,05513966 ! nerve development GO:0021675 34 18 0,000 0,03633846 0,05510543 ! microspike assembly GO:0030035 46 18 0,000 0,03633846 0,05507125 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03633846 0,0550371 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03633846 0,055003 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03831862 0,05796433 ! positive regulation of translation GO:0045727 31 19 0,000 0,03831862 0,05792846 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03831862 0,05789263 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03831862 0,05785685 ! neuron maturation GO:0042551 46 19 0,000 0,03831862 0,05782112 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03831862 0,05778542 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03831862 0,05774978 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03831862 0,05771417 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03831862 0,05767861 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03831862 0,0576431 ! inositol metabolic process GO:0006020 33 19 0,000 0,03831862 0,05760762 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03831862 0,05757219 ! memory GO:0007613 34 19 0,000 0,03831862 0,05753681 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03831862 0,05750147 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03831862 0,05746617 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03831862 0,05743091 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03831862 0,0573957 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03831862 0,05736053 ! cerebral cortex development GO:0021987 40 19 0,000 0,03831862 0,05732541 ! pigmentation during development GO:0048066 42 19 0,000 0,03831862 0,05729032 ! response to vitamin A GO:0033189 32 19 0,000 0,03831862 0,05725528 ! heme metabolic process GO:0042168 40 19 0,000 0,03831862 0,05722029 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03831862 0,05718533 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03831862 0,05715042 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03831862 0,05711555 ! response to fungus GO:0009620 26 19 0,000 0,03831862 0,05708072 ! peptide cross-linking GO:0018149 39 19 0,000 0,03831862 0,05704594 ! protein export from nucleus GO:0006611 40 19 0,000 0,03831862 0,0570112 ! heart process GO:0003015 32 19 0,000 0,03831862 0,0569765 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03831862 0,05694184 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03831862 0,05690723 ! visual learning GO:0008542 38 19 0,000 0,03831862 0,05687265 ! cellular pigmentation GO:0033059 37 19 0,000 0,03831862 0,05683812 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03831862 0,05680363 ! vitamin transport GO:0051180 31 19 0,000 0,03831862 0,05676919 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03831862 0,05673478 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03831862 0,05670042 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03831862 0,05666609 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03831862 0,05663181 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03831862 0,05659757 ! cilium assembly GO:0042384 38 19 0,000 0,03831862 0,05656338 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03831862 0,05652922 ! protein secretion GO:0009306 45 20 0,000 0,04029477 0,05940864 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04029477 0,05937281 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04029477 0,05933702 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04029477 0,05930128 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04029477 0,05926558 ! skin development GO:0043588 42 20 0,000 0,04029477 0,05922992 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04029477 0,0591943 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04029477 0,05915873 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04029477 0,0591232 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04029477 0,05908771 ! response to vitamin GO:0033273 36 20 0,000 0,04029477 0,05905226 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04029477 0,05901686 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04029477 0,0589815 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04029477 0,05894618 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04029477 0,0589109 ! response to alkaloid GO:0043279 38 20 0,000 0,04029477 0,05887567 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04029477 0,05884048 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04029477 0,05880533 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04029477 0,05877022 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04029477 0,05873516 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04029477 0,05870013 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04029477 0,05866515 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04029477 0,05863021 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04029477 0,05859531 ! body fluid secretion GO:0007589 33 20 0,000 0,04029477 0,05856045 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04029477 0,05852564 ! peptide secretion GO:0002790 38 20 0,000 0,04029477 0,05849086 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04029477 0,05845613 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04029477 0,05842144 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04029477 0,05838679 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04029477 0,05835218 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04029477 0,05831761 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04029477 0,05828308 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04029477 0,05824859 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04029477 0,05821415 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04029477 0,05817974 ! regulation of glucose import GO:0046324 30 20 0,000 0,04029477 0,05814538 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04029477 0,05811105 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04029477 0,05807677 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04029477 0,05804252 ! negative regulation of translation GO:0017148 32 20 0,000 0,04029477 0,05800832 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04029477 0,05797416 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04226691 0,06077579 ! hormone secretion GO:0046879 39 21 0,000 0,04226691 0,06074004 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04226691 0,06070433 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04226691 0,06066867 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04226691 0,06063304 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04226691 0,06059746 ! ovarian follicle development GO:0001541 39 21 0,000 0,04226691 0,06056192 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04226691 0,06052642 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04226691 0,06049096 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04226691 0,06045555 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04226691 0,06042017 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04226691 0,06038484 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04226691 0,06034955 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04226691 0,06031429 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04226691 0,06027908 ! diencephalon development GO:0021536 36 21 0,000 0,04226691 0,06024392 ! collagen fibril organization GO:0030199 62 21 0,000 0,04226691 0,06020879 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04226691 0,0601737 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04226691 0,06013866 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04226691 0,06010365 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04226691 0,06006869 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04226691 0,06003376 ! collagen catabolic process GO:0030574 29 21 0,000 0,04226691 0,05999888 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04226691 0,05996404 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04226691 0,05992924 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04226691 0,05989447 ! actin filament-based movement GO:0030048 47 21 0,000 0,04226691 0,05985975 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04226691 0,05982507 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04423506 0,06257456 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04423506 0,06253834 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04423506 0,06250217 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04423506 0,06246604 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04423506 0,06242996 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04423506 0,06239391 ! microtubule-based transport GO:0010970 59 22 0,000 0,04423506 0,06235791 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04423506 0,06232195 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04423506 0,06228603 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04423506 0,06225015 ! cellular response to starvation GO:0009267 37 22 0,000 0,04423506 0,06221431 ! vacuolar transport GO:0007034 41 22 0,000 0,04423506 0,06217851 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04423506 0,06214276 ! fucose metabolic process GO:0006004 44 22 0,000 0,04423506 0,06210704 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04423506 0,06207137 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04423506 0,06203574 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04423506 0,06200015 ! cell aging GO:0007569 48 22 0,000 0,04423506 0,0619646 ! stem cell differentiation GO:0048863 57 22 0,000 0,04423506 0,06192909 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04423506 0,06189362 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04423506 0,06185819 ! cytolysis GO:0019835 27 22 0,000 0,04423506 0,0618228 ! renal system process GO:0003014 42 22 0,000 0,04423506 0,06178745 ! vasodilation GO:0042311 40 22 0,000 0,04423506 0,06175215 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04423506 0,06171688 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04423506 0,06168165 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,04423506 0,06164647 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04423506 0,06161132 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04423506 0,06157622 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04423506 0,06154115 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04423506 0,06150612 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04423506 0,06147114 ! sarcomere organization GO:0045214 32 22 0,000 0,04423506 0,06143619 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04423506 0,06140128 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04423506 0,06136642 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04423506 0,06133159 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04423506 0,0612968 ! gut development GO:0048565 44 22 0,000 0,04423506 0,06126205 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04423506 0,06122734 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04423506 0,06119267 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04423506 0,06115804 ! protein stabilization GO:0050821 41 22 0,000 0,04423506 0,06112345 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04619922 0,06380141 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04619922 0,06376537 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04619922 0,06372936 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04619922 0,0636934 ! gluconeogenesis GO:0006094 38 23 0,000 0,04619922 0,06365747 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04619922 0,06362159 ! viral genome replication GO:0019079 44 23 0,000 0,04619922 0,06358574 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04619922 0,06354994 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04619922 0,06351418 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04619922 0,06347846 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04619922 0,06344278 ! regeneration GO:0031099 42 23 0,000 0,04619922 0,06340713 ! axis specification GO:0009798 43 23 0,000 0,04619922 0,06337153 ! visual behavior GO:0007632 46 23 0,000 0,04619922 0,06333597 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04619922 0,06330045 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 0,000 0,04619922 0,06326496 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04619922 0,06322952 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04619922 0,06319412 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04619922 0,06315876 ! peroxisome organization GO:0007031 43 23 0,000 0,04619922 0,06312343 ! lysosome organization GO:0007040 47 23 0,000 0,04619922 0,06308815 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04619922 0,0630529 ! vesicle targeting GO:0006903 49 23 0,000 0,04619922 0,0630177 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04619922 0,06298253 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04619922 0,0629474 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04619922 0,06291232 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04619922 0,06287727 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04619922 0,06284226 ! DNA modification GO:0006304 36 23 0,000 0,04619922 0,06280729 ! fatty acid transport GO:0015908 47 23 0,000 0,04619922 0,06277236 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04619922 0,06273746 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04619922 0,06270261 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04619922 0,06266779 ! hormone transport GO:0009914 41 23 0,000 0,04619922 0,06263302 ! cell-cell recognition GO:0009988 28 23 0,000 0,04619922 0,06259828 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04619922 0,06256358 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04619922 0,06252892 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04619922 0,0624943 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0481594 0,0651098 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0481594 0,06507379 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0481594 0,06503782 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0481594 0,06500188 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0481594 0,06496599 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0481594 0,06493014 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0481594 0,06489432 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0481594 0,06485855 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0481594 0,06482282 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0481594 0,06478712 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0481594 0,06475146 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0481594 0,06471585 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0481594 0,06468027 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0481594 0,06464473 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0481594 0,06460923 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0481594 0,06457377 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0481594 0,06453835 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0481594 0,06450297 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0481594 0,06446762 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0481594 0,06443232 ! pallium development GO:0021543 56 24 0,000 0,0481594 0,06439705 ! oogenesis GO:0048477 44 24 0,000 0,0481594 0,06436182 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0481594 0,06432663 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0481594 0,06429148 ! platelet activation GO:0030168 41 24 0,000 0,0481594 0,06425637 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0481594 0,06422129 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0481594 0,06418626 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0481594 0,06415126 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0481594 0,0641163 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0481594 0,06408138 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0481594 0,06404649 ! regulation of amine transport GO:0051952 41 24 0,000 0,0481594 0,06401165 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0501156 0,06657554 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,0501156 0,06653936 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0501156 0,06650321 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,0501156 0,06646711 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0501156 0,06643105 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0501156 0,06639502 ! phototransduction GO:0007602 37 25 0,000 0,0501156 0,06635903 ! keratinization GO:0031424 37 25 0,000 0,0501156 0,06632309 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0501156 0,06628718 ! vacuole organization GO:0007033 49 25 0,000 0,0501156 0,06625131 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0501156 0,06621548 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0501156 0,06617968 ! receptor metabolic process GO:0043112 53 25 0,000 0,0501156 0,06614393 ! chromosome condensation GO:0030261 48 25 0,000 0,0501156 0,06610822 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0501156 0,06607254 ! regulation of behavior GO:0050795 48 25 0,000 0,0501156 0,0660369 ! interaction with host GO:0051701 66 25 0,000 0,0501156 0,0660013 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0501156 0,06596574 ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0501156 0,06593022 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0501156 0,06589473 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0501156 0,06585929 ! liver development GO:0001889 55 25 0,000 0,0501156 0,06582388 ! protein tetramerization GO:0051262 57 25 0,000 0,0501156 0,06578851 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05206784 0,06831457 ! myelination GO:0042552 50 26 0,000 0,05206784 0,0682779 ! initiation of viral infection GO:0019059 60 26 0,000 0,05206784 0,06824127 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05206784 0,06820468 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05206784 0,06816813 ! molting cycle process GO:0022404 52 26 0,000 0,05206784 0,06813162 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05206784 0,06809515 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05206784 0,06805871 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05206784 0,06802232 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05206784 0,06798596 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05206784 0,06794964 ! digestive system process GO:0022600 49 26 0,000 0,05206784 0,06791337 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05206784 0,06787713 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,05206784 0,06784093 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05206784 0,06780476 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05206784 0,06776864 ! neural crest cell development GO:0014032 59 26 0,000 0,05206784 0,06773255 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05206784 0,06769651 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05206784 0,0676605 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05206784 0,06762453 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05206784 0,06758859 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05206784 0,0675527 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05206784 0,06751684 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05206784 0,06748103 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05206784 0,06744525 ! blastocyst development GO:0001824 50 26 0,000 0,05206784 0,0674095 ! telomere organization GO:0032200 46 26 0,000 0,05206784 0,0673738 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05206784 0,06733813 ! neural tube closure GO:0001843 58 26 0,000 0,05206784 0,06730251 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05206784 0,06726691 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05206784 0,06723136 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05206784 0,06719585 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05401612 0,06967338 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05401612 0,06963662 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05401612 0,06959989 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05401612 0,0695632 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05401612 0,06952655 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05401612 0,06948993 ! iron ion transport GO:0006826 65 27 0,000 0,05401612 0,06945336 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05401612 0,06941683 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05401612 0,06938033 ! tube lumen formation GO:0035148 59 27 0,000 0,05401612 0,06934387 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05401612 0,06930745 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,05401612 0,06927107 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05401612 0,06923472 ! response to starvation GO:0042594 47 27 0,000 0,05401612 0,06919842 ! response to toxin GO:0009636 49 27 0,000 0,05401612 0,06916215 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05401612 0,06912592 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05401612 0,06908973 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,05401612 0,06905358 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05401612 0,06901746 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05401612 0,06898138 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,05596045 0,07142706 ! neuron fate commitment GO:0048663 52 28 0,000 0,05596045 0,07138976 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05596045 0,0713525 ! protein amino acid acylation GO:0043543 59 28 0,000 0,05596045 0,07131528 ! circadian rhythm GO:0007623 56 28 0,000 0,05596045 0,0712781 ! dendrite development GO:0016358 67 28 0,000 0,05596045 0,07124095 ! fat cell differentiation GO:0045444 57 28 0,000 0,05596045 0,07120385 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05596045 0,07116678 ! sperm motility GO:0030317 37 28 0,000 0,05596045 0,07112975 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05596045 0,07109277 ! base-excision repair GO:0006284 41 28 0,000 0,05596045 0,07105581 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05596045 0,0710189 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05596045 0,07098203 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05596045 0,07094519 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05596045 0,0709084 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05596045 0,07087164 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,05596045 0,07083492 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05596045 0,07079823 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05596045 0,07076159 ! lipid oxidation GO:0034440 48 28 0,000 0,05596045 0,07072498 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05596045 0,07068841 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05596045 0,07065188 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05790084 0,07306393 ! translational initiation GO:0006413 66 29 0,000 0,05790084 0,07302621 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05790084 0,07298852 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05790084 0,07295088 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05790084 0,07291328 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,05790084 0,07287571 ! autophagy GO:0006914 47 29 0,000 0,05790084 0,07283819 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05790084 0,0728007 ! primary neural tube formation GO:0014020 61 29 0,000 0,05790084 0,07276325 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05790084 0,07272584 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05790084 0,07268847 ! somitogenesis GO:0001756 52 29 0,000 0,05790084 0,07265114 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05790084 0,07261384 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05790084 0,07257658 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05790084 0,07253936 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05790084 0,07250218 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0598373 0,07488859 ! phenol metabolic process GO:0018958 56 30 0,000 0,0598373 0,07485024 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0598373 0,07481194 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0598373 0,07477367 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0598373 0,07473544 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0598373 0,07469725 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0598373 0,0746591 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0598373 0,07462099 ! acute-phase response GO:0006953 50 30 0,000 0,0598373 0,07458292 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0598373 0,07454489 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0598373 0,07450689 ! myofibril assembly GO:0030239 50 30 0,000 0,0598373 0,07446894 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0598373 0,07443102 ! cell fate determination GO:0001709 64 30 0,000 0,0598373 0,07439314 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0598373 0,0743553 ! phospholipid transport GO:0015914 65 30 0,000 0,0598373 0,0743175 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0598373 0,07427974 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0598373 0,07424201 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0598373 0,07420433 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,0598373 0,07416668 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,0598373 0,07412907 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06176983 0,07648439 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06176983 0,07644564 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06176983 0,07640693 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06176983 0,07636827 ! cell junction assembly GO:0034329 85 31 0,000 0,06176983 0,07632964 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06176983 0,07629105 ! ovulation cycle process GO:0022602 55 31 0,000 0,06176983 0,0762525 ! peptide transport GO:0015833 60 31 0,000 0,06176983 0,07621399 ! male gonad development GO:0008584 56 31 0,000 0,06176983 0,07617551 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06176983 0,07613708 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06176983 0,07609869 ! detection of light stimulus GO:0009583 44 31 0,000 0,06176983 0,07606033 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,06176983 0,07602201 ! natural killer cell activation GO:0030101 50 31 0,000 0,06176983 0,07598373 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06176983 0,07594549 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06176983 0,07590729 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06176983 0,07586913 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06176983 0,075831 ! eye morphogenesis GO:0048592 65 31 0,000 0,06176983 0,07579291 ! response to heat GO:0009408 54 31 0,000 0,06176983 0,07575487 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06369844 0,07808093 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06369844 0,07804177 ! collagen metabolic process GO:0032963 49 32 0,000 0,06369844 0,07800265 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06369844 0,07796357 ! spindle organization GO:0007051 50 32 0,000 0,06369844 0,07792453 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06369844 0,07788553 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06369844 0,07784657 ! muscle cell development GO:0055001 52 32 0,000 0,06369844 0,07780765 ! mesoderm formation GO:0001707 73 32 0,000 0,06369844 0,07776876 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06369844 0,07772992 ! ovulation cycle GO:0042698 57 32 0,000 0,06369844 0,07769111 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06369844 0,07765234 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06369844 0,07761361 ! hindbrain development GO:0030902 65 32 0,000 0,06369844 0,07757492 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06369844 0,07753627 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,06369844 0,07749766 ! gene silencing GO:0016458 71 32 0,000 0,06369844 0,07745908 ! regulation of pH GO:0006885 56 33 0,000 0,06562314 0,07975987 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06562314 0,07972021 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06562314 0,07968059 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06562314 0,079641 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06562314 0,07960146 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06562314 0,07956196 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06562314 0,07952249 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06562314 0,07948306 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06562314 0,07944368 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06562314 0,07940433 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06562314 0,07936502 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06754394 0,08164763 ! glial cell differentiation GO:0010001 67 34 0,000 0,06754394 0,08160725 ! post-embryonic development GO:0009791 76 34 0,000 0,06754394 0,08156691 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06754394 0,08152661 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06754394 0,08148635 ! spliceosome assembly GO:0000245 75 34 0,000 0,06754394 0,08144613 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06754394 0,08140595 ! formation of primary germ layer GO:0001704 76 34 0,000 0,06754394 0,08136581 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06754394 0,0813257 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06754394 0,08128564 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,06754394 0,08124562 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06946085 0,08351026 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06946085 0,08346918 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06946085 0,08342815 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06946085 0,08338715 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06946085 0,08334619 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06946085 0,08330528 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06946085 0,0832644 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06946085 0,08322357 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06946085 0,08318277 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06946085 0,08314201 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,06946085 0,0831013 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06946085 0,08306062 ! telencephalon development GO:0021537 81 35 0,000 0,06946085 0,08301999 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06946085 0,08297939 ! placenta development GO:0001890 53 35 0,000 0,06946085 0,08293883 ! vesicle localization GO:0051648 70 35 0,000 0,06946085 0,08289832 ! regulation of muscle development GO:0048634 82 36 0,000 0,07137387 0,08513982 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07137387 0,08509827 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07137387 0,08505676 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07137387 0,08501529 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07137387 0,08497386 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07137387 0,08493247 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07137387 0,08489112 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07137387 0,08484981 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,07137387 0,08480854 ! aerobic respiration GO:0009060 56 36 0,000 0,07137387 0,08476731 ! cytokine production GO:0001816 68 36 0,000 0,07137387 0,08472612 ! embryonic organ development GO:0048568 67 36 0,000 0,07137387 0,08468497 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07137387 0,08464386 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07137387 0,08460279 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07328301 0,08682366 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07328301 0,08678157 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07328301 0,08673953 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07328301 0,08669752 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07328301 0,08665556 ! odontogenesis GO:0042476 74 37 0,000 0,07328301 0,08661363 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07328301 0,08657175 ! cell junction organization GO:0034330 96 37 0,000 0,07328301 0,08652991 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07328301 0,08648811 ! female gonad development GO:0008585 71 37 0,000 0,07328301 0,08644635 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07328301 0,08640462 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,07328301 0,08636294 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07328301 0,0863213 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07518827 0,08852287 ! meiosis I GO:0007127 74 38 0,000 0,07518827 0,08848023 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07518827 0,08843763 ! organic anion transport GO:0015711 82 38 0,000 0,07518827 0,08839507 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07518827 0,08835255 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07518827 0,08831007 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07518827 0,08826764 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07518827 0,08822524 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07518827 0,08818289 ! regulation of protein stability GO:0031647 77 38 0,000 0,07518827 0,08814057 ! spermatid development GO:0007286 69 38 0,000 0,07518827 0,0880983 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07518827 0,08805606 ! pigment metabolic process GO:0042440 87 38 0,000 0,07518827 0,08801387 ! neural tube formation GO:0001841 79 38 0,000 0,07518827 0,08797172 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,07708968 0,09015322 ! negative regulation of binding GO:0051100 71 39 0,000 0,07708968 0,09011009 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,07708968 0,09006699 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,07708968 0,09002394 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 0,000 0,07708968 0,08998093 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,07708968 0,08993796 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,07708968 0,08989503 ! glucan metabolic process GO:0044042 64 39 0,000 0,07708968 0,08985214 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07898723 0,09201993 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07898723 0,09197607 ! learning GO:0007612 82 40 0,000 0,07898723 0,09193225 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07898723 0,09188847 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07898723 0,09184474 ! mismatch repair GO:0006298 58 40 0,000 0,07898723 0,09180104 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07898723 0,09175739 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07898723 0,09171378 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08088093 0,09386798 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08088093 0,09382341 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08088093 0,09377888 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,08088093 0,09373439 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,08088093 0,09368995 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08088093 0,09364555 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08088093 0,09360118 ! gliogenesis GO:0042063 91 41 0,000 0,08088093 0,09355687 ! feeding behavior GO:0007631 69 41 0,000 0,08088093 0,09351259 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08088093 0,09346835 ! mesenchymal cell development GO:0014031 94 41 0,000 0,08088093 0,09342416 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,08088093 0,09338001 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08088093 0,0933359 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08088093 0,09329183 ! spermatid differentiation GO:0048515 73 41 0,000 0,08088093 0,09324781 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08088093 0,09320382 ! RNA modification GO:0009451 64 41 0,000 0,08088093 0,09315988 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,08277079 0,09529172 ! ear morphogenesis GO:0042471 64 42 0,000 0,08277079 0,09524683 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,08277079 0,09520199 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,08277079 0,09515719 ! regulation of protein secretion GO:0050708 77 42 0,000 0,08277079 0,09511243 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,08277079 0,09506771 ! cytokinesis GO:0000910 84 42 0,000 0,08277079 0,09502304 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,08277079 0,09497841 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,08465681 0,09709699 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,08465681 0,09705143 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08465681 0,09700591 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08465681 0,09696043 ! regulation of tube size GO:0035150 76 43 0,000 0,08465681 0,09691499 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,08465681 0,0968696 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,08465681 0,09682425 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08465681 0,09677894 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08465681 0,09673367 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08465681 0,09668845 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08465681 0,09664327 ! segmentation GO:0035282 78 43 0,000 0,08465681 0,09659813 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08465681 0,09655303 ! neuron migration GO:0001764 85 43 0,000 0,08465681 0,09650798 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,08465681 0,09646296 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,08653901 0,09856168 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,08653901 0,09851576 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,08653901 0,09846987 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,08653901 0,09842403 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,08653901 0,09837823 ! hexose transport GO:0008645 68 44 0,000 0,08653901 0,09833247 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,08653901 0,09828676 ! striated muscle contraction GO:0006941 85 44 0,000 0,08653901 0,09824108 ! phagocytosis GO:0006909 105 44 0,000 0,08653901 0,09819545 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,08653901 0,09814987 ! double-strand break repair GO:0006302 85 44 0,000 0,08653901 0,09810432 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,0884174 0,10018725 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,0884174 0,1001408 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,0884174 0,1000944 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,0884174 0,10004803 ! biopolymer methylation GO:0043414 91 45 0,000 0,0884174 0,10000172 ! B cell differentiation GO:0030183 124 45 0,000 0,0884174 0,09995544 ! female gamete generation GO:0007292 71 45 0,000 0,0884174 0,09990921 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,0884174 0,09986302 ! polyol metabolic process GO:0019751 77 45 0,000 0,0884174 0,09981687 ! developmental growth GO:0048589 88 45 0,000 0,0884174 0,09977076 ! maintenance of location in cell GO:0051651 101 45 0,000 0,0884174 0,0997247 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09029197 0,10179201 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09029197 0,10174506 ! glycolysis GO:0006096 71 46 0,000 0,09029197 0,10169815 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,09029197 0,10165129 ! leukocyte migration GO:0050900 75 46 0,000 0,09029197 0,10160446 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,09029197 0,10155768 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,09029197 0,10151095 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09029197 0,10146426 ! pigmentation GO:0043473 103 46 0,000 0,09029197 0,10141761 ! neural tube development GO:0021915 91 47 0,000 0,09216275 0,10347132 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,09216275 0,10342379 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09402972 0,10547044 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09402972 0,10542204 ! mitochondrial transport GO:0006839 94 48 0,000 0,09402972 0,10537368 ! cellular component disassembly GO:0022411 89 48 0,000 0,09402972 0,10532536 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09402972 0,10527709 ! endosome transport GO:0016197 127 48 0,000 0,09402972 0,10522887 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,09402972 0,10518069 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09402972 0,10513255 ! male sex differentiation GO:0046661 93 48 0,000 0,09402972 0,10508445 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09402972 0,1050364 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09402972 0,1049884 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09402972 0,10494044 ! methylation GO:0032259 97 48 0,000 0,09402972 0,10489252 ! response to calcium ion GO:0051592 94 49 0,000 0,09589292 0,10692213 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,09589292 0,10687335 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,09589292 0,10682462 ! JNK cascade GO:0007254 106 49 0,000 0,09589292 0,10677593 ! regulation of action potential GO:0001508 102 50 0,000 0,09775233 0,10879678 ! regulation of ion transport GO:0043269 86 50 0,000 0,09775233 0,10874724 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,09775233 0,10869774 ! endocrine system development GO:0035270 109 50 0,000 0,09775233 0,10864829 ! activation of caspase activity GO:0006919 95 50 0,000 0,09775233 0,10859888 ! regulation of ossification GO:0030278 123 50 0,000 0,09775233 0,10854952 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09775233 0,1085002 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09775233 0,10845092 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09775233 0,1084017 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,09775233 0,10835251 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09775233 0,10830337 ! viral infectious cycle GO:0019058 104 51 0,000 0,09960797 0,11030928 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,09960797 0,11025929 ! peptide metabolic process GO:0006518 80 51 0,000 0,09960797 0,11020936 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09960797 0,11015947 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09960797 0,11010962 ! positive regulation of binding GO:0051099 88 52 0,000 0,10145984 0,11210601 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,10145984 0,11205533 ! Notch signaling pathway GO:0007219 111 52 0,000 0,10145984 0,1120047 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,10145984 0,11195411 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,10145984 0,11190356 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,10145984 0,11185307 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,10145984 0,11180261 ! excretion GO:0007588 87 52 0,000 0,10145984 0,11175221 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,10145984 0,11170185 ! histone modification GO:0016570 104 52 0,000 0,10145984 0,11165153 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,10145984 0,11160126 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,10145984 0,11155103 ! amino acid activation GO:0043038 98 52 0,000 0,10145984 0,11150085 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10330796 0,11348082 ! positive regulation of growth GO:0045927 96 53 0,000 0,10330796 0,11342982 ! inner ear development GO:0048839 89 53 0,000 0,10330796 0,11337886 ! chromatin remodeling GO:0006338 122 53 0,000 0,10330796 0,11332795 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10330796 0,11327709 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10330796 0,11322627 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,10330796 0,11317549 ! cartilage development GO:0051216 99 53 0,000 0,10330796 0,11312476 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,10515233 0,11509281 ! regulation of translational initiation GO:0006446 87 54 0,000 0,10515233 0,11504126 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,10515233 0,11498977 ! neuromuscular process GO:0050905 107 54 0,000 0,10515233 0,11493832 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,10515233 0,11488692 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,10515233 0,11483556 ! covalent chromatin modification GO:0016569 115 54 0,000 0,10515233 0,11478425 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,10515233 0,11473298 ! regulation of cell shape GO:0008360 142 54 0,000 0,10515233 0,11468176 ! RNA catabolic process GO:0006401 103 55 0,000 0,10699296 0,11663713 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,10699296 0,1165851 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,10699296 0,11653312 ! cell recognition GO:0008037 98 55 0,000 0,10699296 0,11648119 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,10699296 0,11642931 ! cell maturation GO:0048469 107 55 0,000 0,10699296 0,11637747 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,10699296 0,11632568 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,10882985 0,11827016 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,10882985 0,11821758 ! glucose catabolic process GO:0006007 88 56 0,000 0,10882985 0,11816503 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,10882985 0,11811254 ! regulation of DNA replication GO:0006275 105 56 0,000 0,10882985 0,11806009 ! RNA elongation GO:0006354 90 56 0,000 0,10882985 0,11800769 ! chloride transport GO:0006821 102 57 0,000 0,11066302 0,11994222 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,11066302 0,11988903 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,11066302 0,11983588 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,11066302 0,11978279 ! heart morphogenesis GO:0003007 105 57 0,000 0,11066302 0,11972974 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,11066302 0,11967674 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11249247 0,12160137 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,11249247 0,12154759 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11249247 0,12149385 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11249247 0,12144017 ! aging GO:0007568 112 58 0,000 0,11249247 0,12138653 ! gastrulation GO:0007369 122 58 0,000 0,11249247 0,12133293 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,11249247 0,12127939 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11249247 0,12122589 ! maintenance of location GO:0051235 124 58 0,000 0,11249247 0,12117244 ! nuclear export GO:0051168 110 59 0,000 0,1143182 0,12308478 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1143182 0,12303056 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,11614023 0,12493641 ! DNA catabolic process GO:0006308 94 60 0,000 0,11614023 0,12488142 ! regulation of endocytosis GO:0030100 104 60 0,000 0,11614023 0,12482648 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,11614023 0,12477159 ! adult behavior GO:0030534 104 60 0,000 0,11614023 0,12471674 ! positive regulation of secretion GO:0051047 110 61 0,000 0,11795857 0,1266137 ! regulation of cellular component size GO:0032535 125 61 0,000 0,11795857 0,12655809 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,11795857 0,12650254 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,11795857 0,12644703 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,11795857 0,12639157 ! regulation of heart contraction GO:0008016 123 61 0,000 0,11795857 0,12633616 ! camera-type eye development GO:0043010 126 61 0,000 0,11795857 0,1262808 ! proton transport GO:0015992 117 61 0,000 0,11795857 0,12622548 ! viral reproductive process GO:0022415 132 62 0,000 0,11977321 0,12811119 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,11977321 0,12805512 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,11977321 0,12799911 ! tRNA processing GO:0008033 102 62 0,000 0,11977321 0,12794314 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,12158417 0,12982086 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12158417 0,12976415 ! hydrogen transport GO:0006818 121 64 0,000 0,12339146 0,13163552 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12339146 0,13157806 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,12339146 0,13152065 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,12519508 0,1333849 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,12519508 0,13332676 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,12519508 0,13326866 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,12519508 0,13321062 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,12519508 0,13315263 ! ear development GO:0043583 114 66 0,000 0,12699504 0,13500822 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,12699504 0,13494949 ! gonad development GO:0008406 115 66 0,000 0,12699504 0,13489082 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,12699504 0,13483219 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,12879135 0,13667996 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,12879135 0,13662061 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,12879135 0,13656131 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,12879135 0,13650206 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,12879135 0,13644287 ! secondary metabolic process GO:0019748 125 67 0,000 0,12879135 0,13638373 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,12879135 0,13632463 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,13058401 0,13816229 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,13058401 0,13810248 ! hexose catabolic process GO:0019320 113 68 0,000 0,13058401 0,13804272 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,13058401 0,13798301 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,13058401 0,13792336 ! viral reproduction GO:0016032 142 68 0,000 0,13058401 0,13786375 ! adaptive immune response GO:0002250 126 68 0,000 0,13058401 0,1378042 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,13058401 0,1377447 ! cell projection assembly GO:0030031 138 68 0,000 0,13058401 0,13768525 ! negative regulation of cell size GO:0045792 144 69 0,000 0,13237303 0,13951135 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13237303 0,13945119 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13237303 0,13939108 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,13237303 0,13933103 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13237303 0,13927102 ! developmental maturation GO:0021700 128 69 0,000 0,13237303 0,13921107 ! single fertilization GO:0007338 83 69 0,000 0,13237303 0,13915117 ! cell redox homeostasis GO:0045454 114 70 0,000 0,13415842 0,14096732 ! germ cell development GO:0007281 133 70 0,000 0,13415842 0,14090672 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,13415842 0,14084616 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,13594019 0,14265545 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,13594019 0,1425942 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,13594019 0,142533 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,13594019 0,14247185 ! appendage morphogenesis GO:0035107 150 72 0,000 0,13771834 0,14427354 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,13771834 0,1442117 ! actin filament organization GO:0007015 167 72 0,000 0,13771834 0,14414992 ! B cell activation GO:0042113 179 72 0,000 0,13771834 0,14408818 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,13771834 0,1440265 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,13771834 0,14396487 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,13771834 0,1439033 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,13771834 0,14384177 ! appendage development GO:0048736 151 73 0,000 0,13949288 0,14563295 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,13949288 0,14557074 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,13949288 0,14550859 ! acute inflammatory response GO:0002526 118 74 0,000 0,14126382 0,14729301 ! amino acid transport GO:0006865 148 74 0,000 0,14126382 0,14723017 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,14126382 0,14716739 ! organelle localization GO:0051640 155 74 0,000 0,14126382 0,14710465 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,14303117 0,14888161 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,14303117 0,1488182 ! reproductive structure development GO:0048608 131 75 0,000 0,14303117 0,14875485 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,14303117 0,14869155 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,14303117 0,1486283 ! eye development GO:0001654 155 75 0,000 0,14303117 0,14856511 ! axon guidance GO:0007411 162 75 0,000 0,14303117 0,14850197 ! rhythmic process GO:0048511 142 75 0,000 0,14303117 0,14843889 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,14479493 0,15020552 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,14479493 0,15014177 ! learning or memory GO:0007611 161 76 0,000 0,14479493 0,15007807 ! regulation of blood pressure GO:0008217 134 76 0,000 0,14479493 0,15001442 ! amine catabolic process GO:0009310 136 77 0,000 0,1465551 0,15177368 ! neurotransmitter transport GO:0006836 142 77 0,000 0,1465551 0,15170937 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,1465551 0,15164512 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,1465551 0,15158091 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,1465551 0,15151677 ! regulation of catabolic process GO:0009894 173 77 0,000 0,1465551 0,15145267 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,14831171 0,15320317 ! antigen processing and presentation GO:0019882 117 78 0,000 0,14831171 0,15313842 ! fertilization GO:0009566 99 78 0,000 0,14831171 0,15307372 ! blood coagulation GO:0007596 151 79 0,000 0,15006475 0,15481764 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,15006475 0,15475229 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,15006475 0,15468699 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,15006475 0,15462175 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,15006475 0,15455657 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,15006475 0,15449143 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,15181422 0,15622668 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,15181422 0,15616091 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,15181422 0,15609518 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,15181422 0,15602951 ! meiosis GO:0007126 143 81 0,000 0,15356015 0,15775755 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,15356015 0,15769124 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,15356015 0,15762498 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,15530253 0,15934653 ! protein import into nucleus GO:0006606 174 82 0,000 0,15530253 0,15927963 ! meiotic cell cycle GO:0051321 144 82 0,000 0,15530253 0,15921279 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,15704138 0,16092789 ! exocytosis GO:0006887 153 83 0,000 0,15704138 0,16086041 ! response to drug GO:0042493 149 83 0,000 0,15704138 0,160793 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,15704138 0,16072563 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,15704138 0,16065833 ! nuclear import GO:0051170 177 83 0,000 0,15704138 0,16059108 ! inorganic anion transport GO:0015698 156 83 0,000 0,15704138 0,16052389 ! response to metal ion GO:0010038 158 84 0,000 0,15877669 0,1622298 ! response to nutrient GO:0007584 135 84 0,000 0,15877669 0,16216198 ! digestion GO:0007586 130 84 0,000 0,15877669 0,16209422 ! regulation of ligase activity GO:0051340 147 84 0,000 0,15877669 0,16202651 ! hemostasis GO:0007599 165 85 0,000 0,16050848 0,16372536 ! negative regulation of transport GO:0051051 164 85 0,000 0,16050848 0,16365702 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,16050848 0,16358875 ! negative regulation of growth GO:0045926 168 85 0,000 0,16050848 0,16352053 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,16050848 0,16345237 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,16050848 0,16338426 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,16223676 0,16507472 ! regulation of lyase activity GO:0051339 169 86 0,000 0,16223676 0,165006 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,16396152 0,1666908 ! mitochondrion organization GO:0007005 159 87 0,000 0,16396152 0,16662146 ! alcohol catabolic process GO:0046164 142 87 0,000 0,16396152 0,16655218 ! nucleosome assembly GO:0006334 126 87 0,000 0,16396152 0,16648296 ! cellular respiration GO:0045333 143 88 0,000 0,16568279 0,1681608 ! amine biosynthetic process GO:0009309 146 88 0,000 0,16568279 0,16809097 ! sensory perception of smell GO:0007608 117 88 0,000 0,16568279 0,16802119 ! chromatin assembly GO:0031497 128 88 0,000 0,16568279 0,16795147 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,16568279 0,16788181 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,16740055 0,16955205 ! regulation of DNA binding GO:0051101 167 89 0,000 0,16740055 0,16948179 ! cellular defense response GO:0006968 123 89 0,000 0,16740055 0,16941158 ! protein localization in nucleus GO:0034504 192 89 0,000 0,16740055 0,16934143 ! regulation of neurological system process GO:0031644 175 89 0,000 0,16740055 0,16927134 ! response to inorganic substance GO:0010035 173 90 0,000 0,16911483 0,17093402 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,16911483 0,17086333 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,16911483 0,1707927 ! response to unfolded protein GO:0006986 139 90 0,000 0,16911483 0,17072212 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,17082563 0,17237795 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,17082563 0,17230678 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,17253295 0,17395708 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,17253295 0,17388531 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,17423681 0,17553011 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,17423681 0,17545776 ! vitamin metabolic process GO:0006766 153 93 0,000 0,17423681 0,17538546 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,1759372 0,17702413 ! female pregnancy GO:0007565 166 94 0,000 0,1759372 0,17695125 ! sterol metabolic process GO:0016125 166 94 0,000 0,1759372 0,17687843 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,1759372 0,17680567 ! regulation of defense response GO:0031347 171 95 0,000 0,17763415 0,17843759 ! nucleosome organization GO:0034728 143 95 0,000 0,17763415 0,17836425 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,17763415 0,17829097 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,17763415 0,17821775 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,17763415 0,17814459 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,17763415 0,17807149 ! response to protein stimulus GO:0051789 158 96 0,000 0,17932764 0,17969542 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,1810177 0,18131457 ! transcription initiation GO:0006352 171 97 0,000 0,1810177 0,18124026 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,18270432 0,18285401 ! mRNA transport GO:0051028 185 100 0,000 0,18606729 0,18614349 ! hormone metabolic process GO:0042445 171 100 0,000 0,18606729 0,18606729