pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/676-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,243E-07 2,992E-04 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 9,029E-06 0,01086218 ! protein tetramerization GO:0051262 52 24 2,000 9,029E-06 7,241E-03 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,157E-05 6,959E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,157E-05 5,568E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,62E-05 6,498E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,802E-05 9,632E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,802E-05 8,428E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 3,413E-05 9,124E-03 ! male sex determination GO:0030238 15 6 1,000 4,199E-05 0,0101026 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,199E-05 9,184E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,199E-05 8,419E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 5,872E-05 0,01086792 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 5,872E-05 0,01009164 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 5,872E-05 9,419E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 5,872E-05 8,83E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 5,872E-05 8,311E-03 ! response to tumor cell GO:0002347 13 7 1,000 5,872E-05 7,849E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 5,872E-05 7,436E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 6,174E-05 7,427E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 6,596E-05 7,558E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 6,596E-05 7,214E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,821E-05 8,181E-03 ! ER overload response GO:0006983 12 8 1,000 7,821E-05 7,841E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 7,821E-05 7,527E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 7,821E-05 7,237E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 1,004E-04 8,951E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,004E-04 8,631E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 1,004E-04 8,334E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,004E-04 8,056E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,004E-04 7,796E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,004E-04 7,552E-03 ! response to UV GO:0009411 104 53 2,000 1,009E-04 7,36E-03 ! regulation of DNA replication GO:0006275 101 56 2,000 1,19E-04 8,423E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,254E-04 8,622E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,254E-04 8,382E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,254E-04 8,156E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,254E-04 7,941E-03 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of cell migration GO:0030335 126 57 2,000 1,255E-04 7,742E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,531E-04 9,211E-03 ! nitric oxide metabolic process GO:0046209 15 11 1,000 1,531E-04 8,986E-03 GO:0006809|nitric oxide biosynthetic process, ! regulation of embryonic development GO:0045995 27 11 1,000 1,531E-04 8,772E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,536E-04 8,595E-03 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,772E-04 9,69E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,836E-04 9,814E-03 ! virus-host interaction GO:0019048 29 12 1,000 1,836E-04 9,601E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,836E-04 9,396E-03 ! focal adhesion formation GO:0048041 35 12 1,000 1,836E-04 9,201E-03 ! negative regulation of cell growth GO:0030308 132 67 2,000 2,03E-04 9,969E-03 ! response to X-ray GO:0010165 25 13 1,000 2,167E-04 0,01042724 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,167E-04 0,01022279 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 2,167E-04 0,01002619 ! negative regulation of cell size GO:0045792 134 69 2,000 2,215E-04 0,01005586 ! response to gamma radiation GO:0010332 28 14 1,000 2,525E-04 0,01125179 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,525E-04 0,01104721 ! regulation of RNA stability GO:0043487 32 14 1,000 2,525E-04 0,01084994 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,525E-04 0,01065959 ! cell-matrix adhesion GO:0007160 163 75 2,000 2,835E-04 0,01175831 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,911E-04 0,01186972 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,911E-04 0,0116719 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,911E-04 0,01148055 ! protein oligomerization GO:0051259 139 78 2,000 3,182E-04 0,01234844 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,323E-04 0,01269034 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,323E-04 0,01249206 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 3,323E-04 0,01229987 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,323E-04 0,01211351 ! cell-substrate adhesion GO:0031589 171 81 2,000 3,556E-04 0,01276968 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 3,762E-04 0,01331043 ! negative regulation of growth GO:0045926 155 84 2,000 3,957E-04 0,01379822 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,228E-04 0,01453065 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,228E-04 0,01432599 ! negative regulation of defense response GO:0031348 25 19 1,000 4,72E-04 0,01577192 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,72E-04 0,01555587 ! actin filament bundle formation GO:0051017 42 19 1,000 4,72E-04 0,01534565 ! G1 phase GO:0051318 40 19 1,000 4,72E-04 0,01514105 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,239E-04 0,01658405 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 5,239E-04 0,01636867 ! cellular response to starvation GO:0009267 33 20 1,000 5,239E-04 0,01615882 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 5,239E-04 0,01595427 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,239E-04 0,01575485 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 5,674E-04 0,01685244 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 5,674E-04 0,01664692 ! cell aging GO:0007569 44 21 1,000 5,784E-04 0,01676569 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 6,029E-04 0,01726899 ! interphase GO:0051325 213 98 2,000 6,212E-04 0,01758381 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 6,355E-04 0,01777965 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,355E-04 0,01757529 ! cell cycle arrest GO:0007050 213 100 2,000 6,589E-04 0,01801391 ! positive regulation of DNA replication GO:0045740 43 23 1,000 6,953E-04 0,0187962 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,953E-04 0,01858735 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 6,953E-04 0,01838309 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 6,953E-04 0,01818328 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 6,953E-04 0,01798776 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 7,577E-04 0,01939324 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 7,577E-04 0,01918911 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 7,577E-04 0,01898922 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 8,227E-04 0,02040556 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 8,227E-04 0,02019734 ! negative regulation of DNA replication GO:0008156 42 25 1,000 8,227E-04 0,01999333 ! response to starvation GO:0042594 42 25 1,000 8,227E-04 0,0197934 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 8,227E-04 0,01959742 ! negative regulation of cell development GO:0010721 73 25 1,000 8,227E-04 0,01940529 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 8,227E-04 0,01921689 ! cellular response to nutrient levels GO:0031669 41 25 1,000 8,227E-04 0,01903211 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 8,903E-04 0,02039966 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 8,903E-04 0,02020721 GO:0045936|negative regulation of phosphate metabolic process, ! response to estradiol stimulus GO:0032355 40 26 1,000 8,903E-04 0,02001836 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 8,903E-04 0,01983301 ! mitochondrial membrane organization GO:0007006 57 27 1,000 9,604E-04 0,02120018 ! response to toxin GO:0009636 47 27 1,000 9,604E-04 0,02100745 ! base-excision repair GO:0006284 41 27 1,000 9,604E-04 0,02081819 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 1,033E-03 0,02219538 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,033E-03 0,02199896 ! regulation of pH GO:0006885 43 29 1,000 1,109E-03 0,02339591 ! cell junction assembly GO:0034329 78 30 1,000 1,186E-03 0,0248222 ! regulation of B cell activation GO:0050864 50 30 1,000 1,186E-03 0,02460822 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 1,35E-03 0,02775908 ! response to ionizing radiation GO:0010212 65 32 1,000 1,35E-03 0,02752383 ! positive regulation of catabolic process GO:0009896 64 32 1,000 1,35E-03 0,02729254 ! DNA damage checkpoint GO:0000077 71 33 1,000 1,435E-03 0,02878009 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 1,435E-03 0,02854223 ! xenobiotic metabolic process GO:0006805 51 34 1,000 1,523E-03 0,03004504 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 1,523E-03 0,02980077 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 1,614E-03 0,03131809 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 1,614E-03 0,03106755 ! cell junction organization GO:0034330 86 36 1,000 1,707E-03 0,03259871 ! DNA integrity checkpoint GO:0031570 75 36 1,000 1,707E-03 0,03234203 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 1,803E-03 0,03388638 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 1,901E-03 0,03545332 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 1,901E-03 0,03518061 ! carbohydrate homeostasis GO:0033500 53 38 1,000 1,901E-03 0,03491205 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,901E-03 0,03464757 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 2,001E-03 0,03620666 ! response to xenobiotic stimulus GO:0009410 57 39 1,000 2,001E-03 0,03593646 ! gliogenesis GO:0042063 88 41 1,000 2,21E-03 0,03938794 ! T cell differentiation GO:0030217 81 41 1,000 2,21E-03 0,03909832 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 2,318E-03 0,04070956 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 2,428E-03 0,04234024 ! double-strand break repair GO:0006302 81 44 1,000 2,541E-03 0,04398978 ! B cell differentiation GO:0030183 107 44 1,000 2,541E-03 0,04367556 ! JAK-STAT cascade GO:0007259 71 44 1,000 2,541E-03 0,04336581 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 2,774E-03 0,04700989 ! mitochondrial transport GO:0006839 82 48 1,000 3,017E-03 0,05076592 ! activation of caspase activity GO:0006919 84 48 1,000 3,017E-03 0,05041338 ! regulation of inflammatory response GO:0050727 75 48 1,000 3,017E-03 0,0500657 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 3,017E-03 0,04972279 ! regulation of ossification GO:0030278 117 50 1,000 3,27E-03 0,05351557 ! response to estrogen stimulus GO:0043627 93 51 1,000 3,399E-03 0,05526384 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 3,399E-03 0,05489294 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of growth GO:0045927 90 52 1,000 3,532E-03 0,05664689 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 3,666E-03 0,05841541 ! chloride transport GO:0006821 90 55 1,000 3,942E-03 0,06240232 ! positive regulation of caspase activity GO:0043280 95 55 1,000 3,942E-03 0,06199446 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 1,000 3,942E-03 0,0615919 ! heart morphogenesis GO:0003007 97 55 1,000 3,942E-03 0,06119453 ! nuclear export GO:0051168 97 55 1,000 3,942E-03 0,06080226 ! negative regulation of cell motion GO:0051271 134 55 1,000 3,942E-03 0,06041499 ! nucleotide-excision repair GO:0006289 83 56 1,000 4,084E-03 0,06218891 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 4,228E-03 0,06397593 ! regulation of bone remodeling GO:0046850 137 57 1,000 4,228E-03 0,06357608 ! regulation of tissue remodeling GO:0034103 140 58 1,000 4,374E-03 0,06536712 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 4,523E-03 0,06717056 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 4,674E-03 0,06898606 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 4,674E-03 0,06856541 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 4,674E-03 0,06814986 ! viral reproductive process GO:0022415 126 62 1,000 4,982E-03 0,0722142 ! regulation of homeostatic process GO:0032844 134 62 1,000 4,982E-03 0,07178178 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 5,14E-03 0,0736146 ! actin filament organization GO:0007015 148 66 1,000 5,627E-03 0,08011381 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 5,794E-03 0,08200468 ! activation of MAPK activity GO:0000187 115 67 1,000 5,794E-03 0,08152512 ! negative regulation of kinase activity GO:0033673 131 68 1,000 5,963E-03 0,08341731 ! viral reproduction GO:0016032 134 68 1,000 5,963E-03 0,08293513 ! cell cycle checkpoint GO:0000075 137 69 1,000 6,135E-03 0,0848285 ! B cell activation GO:0042113 160 71 1,000 6,484E-03 0,08914887 ! regulation of caspase activity GO:0043281 122 72 1,000 6,662E-03 0,09107685 ! negative regulation of transferase activity GO:0051348 140 72 1,000 6,662E-03 0,09056229 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 7,025E-03 0,09495748 ! lymphocyte differentiation GO:0030098 167 75 1,000 7,21E-03 0,09690965 ! regulation of catabolic process GO:0009894 161 76 1,000 7,397E-03 0,09886941 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 7,586E-03 0,10083653 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 7,777E-03 0,1028108 ! regulation of peptidase activity GO:0052547 134 79 1,000 7,97E-03 0,10479199 ! protein import into nucleus GO:0006606 158 80 1,000 8,166E-03 0,10677989 ! inorganic anion transport GO:0015698 138 80 1,000 8,166E-03 0,1062027 ! T cell activation GO:0042110 168 81 1,000 8,364E-03 0,10818949 ! nuclear import GO:0051170 161 81 1,000 8,364E-03 0,10761094 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 8,439E-03 0,10800009 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 8,439E-03 0,10742866 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 8,439E-03 0,10686325 ! positive regulation of helicase activity GO:0051096 11 5 0,000 8,439E-03 0,10630376 ! neuron fate determination GO:0048664 7 5 0,000 8,439E-03 0,10575009 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 8,439E-03 0,10520216 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 8,439E-03 0,10465988 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 8,439E-03 0,10412317 ! polyol transport GO:0015791 12 5 0,000 8,439E-03 0,10359193 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 8,439E-03 0,10306608 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 8,439E-03 0,10254554 ! response to superoxide GO:0000303 10 5 0,000 8,439E-03 0,10203024 ! negative regulation of bone resorption GO:0045779 10 5 0,000 8,439E-03 0,10152009 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 8,439E-03 0,10101501 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 8,439E-03 0,10051494 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 8,439E-03 0,10001979 ! female meiosis GO:0007143 7 5 0,000 8,439E-03 0,0995295 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 8,439E-03 0,09904399 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 8,439E-03 0,09856319 ! cobalt ion transport GO:0006824 11 5 0,000 8,439E-03 0,09808704 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 8,439E-03 0,09761547 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 8,439E-03 0,09714841 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 8,439E-03 0,0966858 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 8,439E-03 0,09622757 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 8,439E-03 0,09577367 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 8,439E-03 0,09532402 ! embryonic camera-type eye development GO:0031076 10 5 0,000 8,439E-03 0,09487859 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 8,439E-03 0,09443729 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 8,439E-03 0,09400008 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 8,439E-03 0,0935669 ! adaptation of signaling pathway GO:0022401 7 5 0,000 8,439E-03 0,09313769 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 8,439E-03 0,09271241 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 8,439E-03 0,09229099 ! negative chemotaxis GO:0050919 14 5 0,000 8,439E-03 0,09187338 ! positive regulation of histone modification GO:0031058 5 5 0,000 8,439E-03 0,09145954 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 8,439E-03 0,0910494 ! sensory perception of bitter taste GO:0050913 7 5 0,000 8,439E-03 0,09064293 ! behavioral response to pain GO:0048266 9 5 0,000 8,439E-03 0,09024008 ! clathrin coat assembly GO:0048268 14 5 0,000 8,439E-03 0,08984078 ! Notch receptor processing GO:0007220 8 5 0,000 8,439E-03 0,08944501 ! regulation of dopamine uptake GO:0051584 9 5 0,000 8,439E-03 0,08905271 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 8,439E-03 0,08866383 ! micturition GO:0060073 9 5 0,000 8,439E-03 0,08827834 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 8,439E-03 0,08789618 ! copulation GO:0007620 9 5 0,000 8,439E-03 0,08751732 ! glial cell fate commitment GO:0021781 13 5 0,000 8,439E-03 0,08714171 ! protein maturation by protein folding GO:0022417 13 5 0,000 8,439E-03 0,0867693 ! spermidine metabolic process GO:0008216 7 5 0,000 8,439E-03 0,08640007 ! regulation of potassium ion transport GO:0043266 10 5 0,000 8,439E-03 0,08603397 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 8,439E-03 0,08567096 ! apoptotic cell clearance GO:0043277 20 5 0,000 8,439E-03 0,085311 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 8,439E-03 0,08495405 ! lipoprotein particle clearance GO:0034381 10 5 0,000 8,439E-03 0,08460007 ! grooming behavior GO:0007625 6 5 0,000 8,439E-03 0,08424903 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 8,439E-03 0,0839009 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 8,439E-03 0,08355563 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 8,439E-03 0,08321319 ! response to protozoan GO:0001562 10 5 0,000 8,439E-03 0,08287354 ! lymph vessel development GO:0001945 10 5 0,000 8,439E-03 0,08253666 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 8,439E-03 0,0822025 ! endochondral ossification GO:0001958 16 5 0,000 8,439E-03 0,08187104 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 8,439E-03 0,08154224 ! parathyroid gland development GO:0060017 13 5 0,000 8,439E-03 0,08121607 ! anagen GO:0042640 6 5 0,000 8,439E-03 0,0808925 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 8,439E-03 0,0805715 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 8,439E-03 0,08025303 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 8,439E-03 0,07993708 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 8,439E-03 0,0796236 ! dorsal spinal cord development GO:0021516 7 5 0,000 8,439E-03 0,07931257 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 8,439E-03 0,07900396 ! sphingoid catabolic process GO:0046521 6 5 0,000 8,439E-03 0,07869774 ! skeletal myofibril assembly GO:0014866 10 5 0,000 8,439E-03 0,07839389 ! smooth muscle tissue development GO:0048745 28 5 0,000 8,439E-03 0,07809237 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 8,439E-03 0,07779317 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 8,439E-03 0,07749625 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 8,439E-03 0,07720159 ! cardiac muscle fiber development GO:0048739 10 5 0,000 8,439E-03 0,07690916 ! transepithelial chloride transport GO:0030321 9 5 0,000 8,439E-03 0,07661893 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 8,439E-03 0,07633089 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 8,439E-03 0,07604501 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 8,439E-03 0,07576126 ! neutrophil mediated immunity GO:0002446 7 5 0,000 8,439E-03 0,07547962 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 8,439E-03 0,07520006 ! histidine catabolic process GO:0006548 6 5 0,000 8,439E-03 0,07492257 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 8,439E-03 0,07464712 ! microvillus organization GO:0032528 7 5 0,000 8,439E-03 0,07437369 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 8,439E-03 0,07410225 ! L-serine biosynthetic process GO:0006564 6 5 0,000 8,439E-03 0,07383279 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 8,439E-03 0,07356528 ! tryptophan metabolic process GO:0006568 9 5 0,000 8,439E-03 0,0732997 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 8,439E-03 0,07303603 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 8,439E-03 0,07277426 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 8,439E-03 0,07251435 ! polyol catabolic process GO:0046174 7 5 0,000 8,439E-03 0,07225629 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 8,439E-03 0,07200006 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 8,439E-03 0,07174564 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 8,439E-03 0,07149302 ! muscle cell migration GO:0014812 8 5 0,000 8,439E-03 0,07124217 ! mitochondrial fission GO:0000266 8 5 0,000 8,439E-03 0,07099307 ! sister chromatid cohesion GO:0007062 12 5 0,000 8,439E-03 0,0707457 ! mRNA transcription GO:0009299 9 5 0,000 8,439E-03 0,07050006 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 8,439E-03 0,07025612 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 8,439E-03 0,07001385 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 8,439E-03 0,06977326 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 8,439E-03 0,06953431 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 8,439E-03 0,06929699 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 8,439E-03 0,06906128 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 8,439E-03 0,06882718 ! response to food GO:0032094 6 5 0,000 8,439E-03 0,06859465 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 8,439E-03 0,06836369 ! positive regulation of transporter activity GO:0032411 8 5 0,000 8,439E-03 0,06813429 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 8,439E-03 0,06790641 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 8,439E-03 0,06768006 ! paraxial mesoderm development GO:0048339 14 5 0,000 8,439E-03 0,06745521 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 8,439E-03 0,06723185 ! forebrain neuron development GO:0021884 13 5 0,000 8,439E-03 0,06700996 ! lipoprotein catabolic process GO:0042159 11 5 0,000 8,439E-03 0,06678953 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 8,439E-03 0,06657055 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 8,439E-03 0,066353 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 8,439E-03 0,06613686 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 8,439E-03 0,06592213 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 8,439E-03 0,06570879 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 8,439E-03 0,06549683 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 8,439E-03 0,06528623 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 8,439E-03 0,06507698 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 8,439E-03 0,06486906 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 8,439E-03 0,06466248 ! basic amino acid transport GO:0015802 11 5 0,000 8,439E-03 0,0644572 ! cellular glucose homeostasis GO:0001678 5 5 0,000 8,439E-03 0,06425322 ! early endosome to late endosome transport GO:0045022 12 5 0,000 8,439E-03 0,06405053 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 8,439E-03 0,06384911 ! depyrimidination GO:0045008 10 5 0,000 8,439E-03 0,06364896 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 8,439E-03 0,06345005 ! regulation of centrosome cycle GO:0046605 7 5 0,000 8,439E-03 0,06325239 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 8,439E-03 0,06305595 ! zinc ion homeostasis GO:0055069 8 5 0,000 8,439E-03 0,06286073 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 8,439E-03 0,06266672 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 8,439E-03 0,0624739 ! forebrain morphogenesis GO:0048853 13 5 0,000 8,439E-03 0,06228226 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 8,439E-03 0,0620918 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 8,439E-03 0,06190249 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 8,439E-03 0,06171434 ! peptidyl-arginine modification GO:0018195 9 5 0,000 8,439E-03 0,06152733 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 8,439E-03 0,06134144 ! positive regulation of organ growth GO:0046622 6 5 0,000 8,439E-03 0,06115668 ! response to arsenic GO:0046685 10 5 0,000 8,439E-03 0,06097302 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 8,439E-03 0,06079047 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 8,439E-03 0,06060901 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 8,439E-03 0,06042862 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 8,439E-03 0,06024931 ! response to cadmium ion GO:0046686 7 5 0,000 8,439E-03 0,06007106 ! bile acid biosynthetic process GO:0006699 6 5 0,000 8,439E-03 0,05989386 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 8,439E-03 0,0597177 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 8,439E-03 0,05954257 ! decidualization GO:0046697 11 5 0,000 8,439E-03 0,05936847 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 8,439E-03 0,05919539 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 8,439E-03 0,05902331 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 8,439E-03 0,05885222 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 8,439E-03 0,05868213 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 8,439E-03 0,05851302 ! base conversion or substitution editing GO:0016553 5 5 0,000 8,439E-03 0,05834488 ! neural tube patterning GO:0021532 7 5 0,000 8,439E-03 0,0581777 ! embryonic cleavage GO:0040016 6 5 0,000 8,439E-03 0,05801148 ! peroxisome fission GO:0016559 5 5 0,000 8,439E-03 0,0578462 ! histone demethylation GO:0016577 10 5 0,000 8,439E-03 0,05768187 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 8,439E-03 0,05751846 ! mitotic recombination GO:0006312 9 5 0,000 8,439E-03 0,05735598 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 8,439E-03 0,05719441 ! metaphase plate congression GO:0051310 7 5 0,000 8,439E-03 0,05703376 ! regulation of sterol transport GO:0032371 7 5 0,000 8,439E-03 0,056874 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 8,439E-03 0,05671513 ! enteric nervous system development GO:0048484 8 5 0,000 8,439E-03 0,05655715 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 8,439E-03 0,05640005 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 8,439E-03 0,05624382 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 8,439E-03 0,05608845 ! muscle cell proliferation GO:0033002 11 5 0,000 8,439E-03 0,05593393 ! skeletal muscle regeneration GO:0043403 8 5 0,000 8,439E-03 0,05578027 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 8,439E-03 0,05562744 ! plasminogen activation GO:0031639 5 5 0,000 8,439E-03 0,05547546 ! B cell homeostasis GO:0001782 13 5 0,000 8,439E-03 0,0553243 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 8,439E-03 0,05517396 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 8,439E-03 0,05502444 ! metaphase GO:0051323 8 5 0,000 8,439E-03 0,05487572 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 8,439E-03 0,05472781 ! cellular response to nutrient GO:0031670 8 5 0,000 8,439E-03 0,05458069 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 8,439E-03 0,05443436 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 8,439E-03 0,05428882 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 8,439E-03 0,05414405 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 8,439E-03 0,05400005 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 8,439E-03 0,05385681 ! response to redox state GO:0051775 5 5 0,000 8,439E-03 0,05371433 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 8,439E-03 0,05357261 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 8,439E-03 0,05343162 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 8,439E-03 0,05329138 ! regulation of telomerase activity GO:0051972 6 5 0,000 8,439E-03 0,05315188 ! galactolipid metabolic process GO:0019374 7 5 0,000 8,439E-03 0,0530131 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 8,439E-03 0,05287505 ! porphyrin catabolic process GO:0006787 12 5 0,000 8,439E-03 0,05273771 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 8,439E-03 0,05260108 ! striatum development GO:0021756 9 5 0,000 8,439E-03 0,05246516 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 8,439E-03 0,05232994 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 8,439E-03 0,05219542 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 8,439E-03 0,05206158 ! glial cell migration GO:0008347 11 5 0,000 8,439E-03 0,05192843 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 8,439E-03 0,05179596 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 8,439E-03 0,05166417 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 8,439E-03 0,05153304 ! somatic stem cell maintenance GO:0035019 15 5 0,000 8,439E-03 0,05140258 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 8,439E-03 0,05127277 ! negative regulation of lipase activity GO:0060192 8 5 0,000 8,439E-03 0,05114362 ! neuroprotection GO:0043526 6 5 0,000 8,439E-03 0,05101512 ! neural plate development GO:0001840 8 5 0,000 8,439E-03 0,05088726 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 8,439E-03 0,05076004 ! regulation of sensory perception GO:0051931 7 5 0,000 8,439E-03 0,05063346 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 8,439E-03 0,05050751 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 8,439E-03 0,05038218 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 8,439E-03 0,05025747 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 8,439E-03 0,05013338 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 8,439E-03 0,05000989 ! sequestering of calcium ion GO:0051208 7 5 0,000 8,439E-03 0,04988702 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 8,439E-03 0,04976475 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 8,439E-03 0,04964307 ! spindle assembly GO:0051225 6 5 0,000 8,439E-03 0,04952199 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 8,439E-03 0,0494015 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 8,439E-03 0,0492816 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 8,439E-03 0,04916227 ! drug metabolic process GO:0017144 6 5 0,000 8,439E-03 0,04904352 ! stem cell division GO:0017145 11 5 0,000 8,439E-03 0,04892534 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 8,439E-03 0,04880773 ! organ regeneration GO:0031100 7 5 0,000 8,439E-03 0,04869069 ! carnitine metabolic process GO:0009437 7 5 0,000 8,439E-03 0,0485742 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 8,439E-03 0,04845828 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 8,439E-03 0,0483429 ! response to drug GO:0042493 143 82 1,000 8,564E-03 0,04894098 ! positive regulation of cell activation GO:0050867 145 85 1,000 9,176E-03 0,05231672 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 148 86 1,000 9,384E-03 0,05337831 ! protein localization in nucleus GO:0034504 176 87 1,000 9,595E-03 0,05444685 ! gland development GO:0048732 206 88 1,000 9,808E-03 0,05552225 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,01002223 0,05660442 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01011829 0,05701315 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01011829 0,05687994 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01011829 0,05674736 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01011829 0,05661539 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01011829 0,05648403 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01011829 0,05635328 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01011829 0,05622313 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01011829 0,05609358 ! sleep GO:0030431 13 6 0,000 0,01011829 0,05596463 ! response to oxygen radical GO:0000305 11 6 0,000 0,01011829 0,05583627 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01011829 0,0557085 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01011829 0,05558131 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01011829 0,05545471 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01011829 0,05532867 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01011829 0,05520321 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01011829 0,05507832 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01011829 0,05495399 ! forebrain regionalization GO:0021871 8 6 0,000 0,01011829 0,05483022 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01011829 0,054707 ! male meiosis GO:0007140 7 6 0,000 0,01011829 0,05458434 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01011829 0,05446223 ! response to zinc ion GO:0010043 9 6 0,000 0,01011829 0,05434066 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01011829 0,05421963 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01011829 0,05409915 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01011829 0,05397919 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01011829 0,05385977 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01011829 0,05374087 ! malate metabolic process GO:0006108 11 6 0,000 0,01011829 0,0536225 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01011829 0,05350465 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01011829 0,05338731 ! protein refolding GO:0042026 15 6 0,000 0,01011829 0,05327049 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01011829 0,05315418 ! opsonization GO:0008228 8 6 0,000 0,01011829 0,05303838 ! mating behavior GO:0007617 7 6 0,000 0,01011829 0,05292308 ! neuron remodeling GO:0016322 15 6 0,000 0,01011829 0,05280828 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01011829 0,05269397 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01011829 0,05258016 ! equilibrioception GO:0050957 14 6 0,000 0,01011829 0,05246684 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01011829 0,05235401 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01011829 0,05224166 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01011829 0,0521298 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01011829 0,05201841 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01011829 0,0519075 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01011829 0,05179705 ! toxin metabolic process GO:0009404 11 6 0,000 0,01011829 0,05168708 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01011829 0,05157758 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01011829 0,05146853 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01011829 0,05135995 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01011829 0,05125182 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01011829 0,05114415 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01011829 0,05103693 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01011829 0,05093016 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01011829 0,05082383 ! thymic T cell selection GO:0045061 12 6 0,000 0,01011829 0,05071795 ! protein lipoylation GO:0009249 10 6 0,000 0,01011829 0,05061251 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01011829 0,0505075 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01011829 0,05040293 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01011829 0,05029879 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01011829 0,05019508 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01011829 0,0500918 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01011829 0,04998894 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01011829 0,04988651 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01011829 0,04978449 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01011829 0,04968289 ! hyperosmotic response GO:0006972 9 6 0,000 0,01011829 0,0495817 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01011829 0,04948093 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01011829 0,04938056 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01011829 0,0492806 ! urea metabolic process GO:0019627 7 6 0,000 0,01011829 0,04918104 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01011829 0,04908189 ! neutrophil activation GO:0042119 8 6 0,000 0,01011829 0,04898313 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01011829 0,04888477 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01011829 0,0487868 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01011829 0,04868923 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01011829 0,04859205 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01011829 0,04849525 ! neuron apoptosis GO:0051402 9 6 0,000 0,01011829 0,04839884 ! nucleoside salvage GO:0043174 9 6 0,000 0,01011829 0,04830281 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01011829 0,04820716 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01011829 0,04811189 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01011829 0,04801699 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01011829 0,04792247 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01011829 0,04782832 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01011829 0,04773454 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01011829 0,04764113 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01011829 0,04754808 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01011829 0,04745539 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01011829 0,04736307 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01011829 0,0472711 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01011829 0,04717949 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01011829 0,04708823 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01011829 0,04699733 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01011829 0,04690677 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01011829 0,04681657 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01011829 0,04672671 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01011829 0,04663719 ! neural nucleus development GO:0048857 14 6 0,000 0,01011829 0,04654802 ! response to UV-C GO:0010225 11 6 0,000 0,01011829 0,04645919 ! astrocyte development GO:0014002 15 6 0,000 0,01011829 0,0463707 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01011829 0,04628254 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01011829 0,04619472 ! interaction with symbiont GO:0051702 13 6 0,000 0,01011829 0,04610723 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01011829 0,04602007 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01011829 0,04593324 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01011829 0,04584673 ! response to copper ion GO:0046688 10 6 0,000 0,01011829 0,04576056 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01011829 0,0456747 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01011829 0,04558917 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01011829 0,04550395 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01011829 0,04541906 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01011829 0,04533448 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01011829 0,04525021 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01011829 0,04516626 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01011829 0,04508262 ! hair follicle maturation GO:0048820 7 6 0,000 0,01011829 0,04499929 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01011829 0,04491626 ! Schwann cell development GO:0014044 15 6 0,000 0,01011829 0,04483355 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01011829 0,04475113 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01011829 0,04466902 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01011829 0,04458721 ! subpallium development GO:0021544 10 6 0,000 0,01011829 0,0445057 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01011829 0,04442448 ! histone ubiquitination GO:0016574 8 6 0,000 0,01011829 0,04434356 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01011829 0,04426294 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01011829 0,04418261 ! G2 phase GO:0051319 16 6 0,000 0,01011829 0,04410256 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01011829 0,04402281 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01011829 0,04394335 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01011829 0,04386417 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01011829 0,04378528 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01011829 0,04370667 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01011829 0,04362834 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01011829 0,0435503 ! receptor internalization GO:0031623 10 6 0,000 0,01011829 0,04347253 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01011829 0,04339504 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01011829 0,04331782 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01011829 0,04324088 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01011829 0,04316421 ! protein deubiquitination GO:0016579 14 6 0,000 0,01011829 0,04308782 ! protein destabilization GO:0031648 9 6 0,000 0,01011829 0,04301169 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01011829 0,04293583 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01011829 0,04286024 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01011829 0,04278491 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01011829 0,04270985 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01011829 0,04263505 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01011829 0,04256052 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01011829 0,04248624 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01011829 0,04241222 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01011829 0,04233846 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01011829 0,04226496 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01011829 0,04219171 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01011829 0,04211871 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01011829 0,04204597 ! catecholamine transport GO:0051937 9 6 0,000 0,01011829 0,04197348 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01011829 0,04190123 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01011829 0,04182924 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01011829 0,04175749 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01011829 0,04168599 ! maternal placenta development GO:0001893 12 6 0,000 0,01011829 0,04161473 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01011829 0,04154371 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01011829 0,04147294 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01011829 0,04140241 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01011829 0,04133211 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01011829 0,04126206 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01011829 0,04119224 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01011829 0,04112266 ! regulation of defense response GO:0031347 149 92 1,000 0,01067876 0,04332732 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,01090174 0,04415756 ! leukocyte differentiation GO:0002521 202 96 1,000 0,01158299 0,0468381 ! tRNA transcription GO:0009304 14 7 0,000 0,01179489 0,04761494 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01179489 0,04753518 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01179489 0,04745569 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01179489 0,04737647 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01179489 0,04729751 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01179489 0,04721881 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01179489 0,04714037 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01179489 0,0470622 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01179489 0,04698428 ! prostate gland development GO:0030850 13 7 0,000 0,01179489 0,04690662 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01179489 0,04682922 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01179489 0,04675207 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01179489 0,04667517 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01179489 0,04659853 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01179489 0,04652214 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01179489 0,046446 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01179489 0,04637011 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01179489 0,04629446 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01179489 0,04621906 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01179489 0,04614391 ! glycolipid transport GO:0046836 10 7 0,000 0,01179489 0,046069 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01179489 0,04599433 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01179489 0,04591991 ! neuron adhesion GO:0007158 12 7 0,000 0,01179489 0,04584573 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01179489 0,04577178 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01179489 0,04569807 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01179489 0,04562461 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01179489 0,04555137 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01179489 0,04547837 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01179489 0,04540561 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01179489 0,04533307 ! mRNA stabilization GO:0048255 18 7 0,000 0,01179489 0,04526077 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01179489 0,0451887 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01179489 0,04511686 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01179489 0,04504524 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01179489 0,04497386 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01179489 0,0449027 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01179489 0,04483176 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01179489 0,04476105 ! lipoprotein transport GO:0042953 14 7 0,000 0,01179489 0,04469056 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01179489 0,04462029 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01179489 0,04455024 ! rhythmic behavior GO:0007622 15 7 0,000 0,01179489 0,04448041 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01179489 0,0444108 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01179489 0,04434141 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01179489 0,04427224 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01179489 0,04420328 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01179489 0,04413453 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01179489 0,044066 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01179489 0,04399768 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01179489 0,04392957 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01179489 0,04386168 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01179489 0,04379399 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01179489 0,04372651 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01179489 0,04365924 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01179489 0,04359217 ! spinal cord patterning GO:0021511 13 7 0,000 0,01179489 0,04352531 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01179489 0,04345866 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01179489 0,04339221 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01179489 0,04332596 ! adrenal gland development GO:0030325 17 7 0,000 0,01179489 0,04325992 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01179489 0,04319407 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01179489 0,04312843 ! ovulation GO:0030728 9 7 0,000 0,01179489 0,04306298 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01179489 0,04299773 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01179489 0,04293268 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01179489 0,04286783 ! microtubule nucleation GO:0007020 20 7 0,000 0,01179489 0,04280317 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01179489 0,04273871 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01179489 0,04267444 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01179489 0,04261037 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01179489 0,04254648 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01179489 0,04248279 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01179489 0,04241929 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01179489 0,04235598 ! galactose metabolic process GO:0006012 13 7 0,000 0,01179489 0,04229285 ! vesicle fusion GO:0006906 17 7 0,000 0,01179489 0,04222992 ! response to dietary excess GO:0002021 8 7 0,000 0,01179489 0,04216717 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01179489 0,04210461 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01179489 0,04204223 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01179489 0,04198004 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01179489 0,04191803 ! organ growth GO:0035265 15 7 0,000 0,01179489 0,0418562 ! purine salvage GO:0043101 10 7 0,000 0,01179489 0,04179456 ! nucleoside transport GO:0015858 8 7 0,000 0,01179489 0,04173309 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01179489 0,04167181 ! parturition GO:0007567 14 7 0,000 0,01179489 0,04161071 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01179489 0,04154979 ! rRNA modification GO:0000154 14 7 0,000 0,01179489 0,04148904 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01179489 0,04142847 ! spindle checkpoint GO:0031577 15 7 0,000 0,01179489 0,04136808 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01179489 0,04130787 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01179489 0,04124783 ! macrophage differentiation GO:0030225 11 7 0,000 0,01179489 0,04118796 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01179489 0,04112827 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01179489 0,04106875 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01179489 0,0410094 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01179489 0,04095022 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01179489 0,04089122 ! fibrinolysis GO:0042730 10 7 0,000 0,01179489 0,04083238 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01179489 0,04077371 ! eating behavior GO:0042755 7 7 0,000 0,01179489 0,04071521 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01179489 0,04065688 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01179489 0,04059872 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01179489 0,04054072 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01179489 0,04048289 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01179489 0,04042522 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01179489 0,04036772 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01179489 0,04031038 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01179489 0,0402532 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01179489 0,04019618 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01179489 0,04013933 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01179489 0,04008263 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01179489 0,0400261 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01179489 0,03996972 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01179489 0,03991351 ! regulation of meiosis GO:0040020 12 7 0,000 0,01179489 0,03985745 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01179489 0,03980155 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01179489 0,0397458 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01179489 0,03969022 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01179489 0,03963478 ! transcription termination GO:0006353 13 7 0,000 0,01179489 0,0395795 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01179489 0,03952438 ! anaphase GO:0051322 17 7 0,000 0,01179489 0,03946941 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01179489 0,03941459 ! axonal fasciculation GO:0007413 18 7 0,000 0,01179489 0,03935992 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01179489 0,03930541 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01179489 0,03925104 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01179489 0,03919683 ! diuresis GO:0030146 12 7 0,000 0,01179489 0,03914276 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01179489 0,03908885 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01179489 0,03903508 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01179489 0,03898146 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01179489 0,03892799 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01179489 0,03887466 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01179489 0,03882148 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01179489 0,03876845 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01179489 0,03871556 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01179489 0,03866281 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01179489 0,03861021 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01179489 0,03855775 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01179489 0,03850543 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01179489 0,03845326 ! lymph node development GO:0048535 10 7 0,000 0,01179489 0,03840122 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01179489 0,03834933 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01179489 0,03829758 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01179489 0,03824596 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01179489 0,03819449 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01179489 0,03814315 ! adult feeding behavior GO:0008343 9 7 0,000 0,01179489 0,03809195 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01179489 0,03804089 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01179489 0,03798997 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01179489 0,03793918 ! muscle adaptation GO:0043500 14 7 0,000 0,01179489 0,03788852 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01179489 0,03783801 ! retina homeostasis GO:0001895 12 7 0,000 0,01179489 0,03778762 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01179489 0,03773737 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01179489 0,03768726 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01179489 0,03763727 ! protein prenylation GO:0018342 18 7 0,000 0,01179489 0,03758742 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01179489 0,0375377 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01179489 0,03748812 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01179489 0,03743866 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0134687 0,04269525 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0134687 0,04263907 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,0134687 0,04258304 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0134687 0,04252716 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0134687 0,04247142 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0134687 0,04241583 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0134687 0,04236039 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0134687 0,04230508 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0134687 0,04224993 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0134687 0,04219491 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0134687 0,04214004 ! meiotic prophase I GO:0007128 13 8 0,000 0,0134687 0,04208532 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0134687 0,04203073 ! oligopeptide transport GO:0006857 15 8 0,000 0,0134687 0,04197629 ! UTP metabolic process GO:0046051 8 8 0,000 0,0134687 0,04192199 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0134687 0,04186782 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0134687 0,0418138 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0134687 0,04175992 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0134687 0,04170617 ! succinate metabolic process GO:0006105 14 8 0,000 0,0134687 0,04165256 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0134687 0,04159909 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0134687 0,04154576 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0134687 0,04149257 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0134687 0,04143951 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0134687 0,04138658 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0134687 0,04133379 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0134687 0,04128114 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0134687 0,04122862 ! reflex GO:0060004 16 8 0,000 0,0134687 0,04117623 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0134687 0,04112398 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0134687 0,04107186 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0134687 0,04101987 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0134687 0,04096801 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0134687 0,04091628 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0134687 0,04086468 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0134687 0,04081322 ! pigment granule organization GO:0048753 16 8 0,000 0,0134687 0,04076188 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0134687 0,04071067 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0134687 0,04065959 ! histidine metabolic process GO:0006547 16 8 0,000 0,0134687 0,04060864 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0134687 0,04055782 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0134687 0,04050712 ! glycine catabolic process GO:0006546 13 8 0,000 0,0134687 0,04045655 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0134687 0,0404061 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0134687 0,04035578 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0134687 0,04030559 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0134687 0,04025552 ! melanin metabolic process GO:0006582 15 8 0,000 0,0134687 0,04020558 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0134687 0,04015576 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0134687 0,04010606 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0134687 0,04005648 ! macrophage activation GO:0042116 12 8 0,000 0,0134687 0,04000703 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0134687 0,0399577 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0134687 0,03990849 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0134687 0,0398594 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0134687 0,03981044 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0134687 0,03976159 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0134687 0,03971286 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0134687 0,03966425 ! osteoblast development GO:0002076 16 8 0,000 0,0134687 0,03961576 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0134687 0,03956739 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0134687 0,03951914 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0134687 0,039471 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0134687 0,03942299 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0134687 0,03937508 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0134687 0,0393273 ! response to UV-B GO:0010224 16 8 0,000 0,0134687 0,03927963 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0134687 0,03923208 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0134687 0,03918464 ! intermediate filament organization GO:0045109 12 8 0,000 0,0134687 0,03913731 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0134687 0,0390901 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0134687 0,03904301 ! cellular extravasation GO:0045123 12 8 0,000 0,0134687 0,03899602 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0134687 0,03894915 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0134687 0,03890239 ! response to antibiotic GO:0046677 11 8 0,000 0,0134687 0,03885575 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0134687 0,03880922 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0134687 0,03876279 ! DNA topological change GO:0006265 12 8 0,000 0,0134687 0,03871648 ! response to tropane GO:0014073 15 8 0,000 0,0134687 0,03867028 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0134687 0,03862419 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0134687 0,03857821 ! melanosome transport GO:0032402 13 8 0,000 0,0134687 0,03853234 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0134687 0,03848657 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0134687 0,03844092 ! mast cell activation GO:0045576 14 8 0,000 0,0134687 0,03839537 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0134687 0,03834993 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0134687 0,0383046 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0134687 0,03825938 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0134687 0,03821426 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0134687 0,03816925 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0134687 0,03812435 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0134687 0,03807955 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0134687 0,03803485 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0134687 0,03799026 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0134687 0,03794578 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0134687 0,0379014 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0134687 0,03785712 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0134687 0,03781295 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0134687 0,03776887 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0134687 0,03772491 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0134687 0,03768104 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0134687 0,03763728 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0134687 0,03759361 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0134687 0,03755005 ! hormone catabolic process GO:0042447 17 8 0,000 0,0134687 0,03750659 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0134687 0,03746323 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0134687 0,03741997 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0134687 0,03737681 ! ATP catabolic process GO:0006200 11 8 0,000 0,0134687 0,03733375 ! blastocyst growth GO:0001832 19 8 0,000 0,0134687 0,03729079 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0134687 0,03724792 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0134687 0,03720516 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0134687 0,03716249 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0134687 0,03711993 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0134687 0,03707745 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0134687 0,03703508 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0134687 0,0369928 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0134687 0,03695062 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0134687 0,03690854 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0134687 0,03686655 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0134687 0,03682465 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0134687 0,03678285 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0134687 0,03674115 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0134687 0,03669954 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0134687 0,03665803 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0134687 0,0366166 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0134687 0,03657528 ! axon extension GO:0048675 15 9 0,000 0,01513973 0,04106674 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01513973 0,04102049 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01513973 0,04097435 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01513973 0,04092831 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01513973 0,04088238 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01513973 0,04083654 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01513973 0,04079081 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01513973 0,04074519 ! phosphate transport GO:0006817 19 9 0,000 0,01513973 0,04069966 ! reproductive behavior GO:0019098 19 9 0,000 0,01513973 0,04065424 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01513973 0,04060892 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01513973 0,04056369 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01513973 0,04051857 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01513973 0,04047355 ! GTP metabolic process GO:0046039 9 9 0,000 0,01513973 0,04042863 ! RNA methylation GO:0001510 15 9 0,000 0,01513973 0,04038381 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01513973 0,04033909 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01513973 0,04029447 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01513973 0,04024994 ! artery development GO:0060840 24 9 0,000 0,01513973 0,04020552 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01513973 0,04016119 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01513973 0,04011696 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01513973 0,04007282 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01513973 0,04002879 ! chemosensory behavior GO:0007635 20 9 0,000 0,01513973 0,03998485 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01513973 0,03994101 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01513973 0,03989726 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01513973 0,03985361 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01513973 0,03981005 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01513973 0,03976659 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01513973 0,03972322 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01513973 0,03967995 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01513973 0,03963678 ! protein targeting to ER GO:0045047 22 9 0,000 0,01513973 0,03959369 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01513973 0,0395507 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01513973 0,03950781 ! T cell selection GO:0045058 23 9 0,000 0,01513973 0,039465 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01513973 0,03942229 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01513973 0,03937967 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01513973 0,03933715 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01513973 0,03929471 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01513973 0,03925237 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01513973 0,03921012 ! mannose metabolic process GO:0006013 13 9 0,000 0,01513973 0,03916795 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01513973 0,03912588 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01513973 0,0390839 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01513973 0,03904201 ! receptor clustering GO:0043113 18 9 0,000 0,01513973 0,03900021 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01513973 0,0389585 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01513973 0,03891688 ! ruffle organization GO:0031529 15 9 0,000 0,01513973 0,03887534 ! retinol metabolic process GO:0042572 18 9 0,000 0,01513973 0,0388339 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01513973 0,03879254 ! behavioral fear response GO:0001662 22 9 0,000 0,01513973 0,03875127 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01513973 0,03871009 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01513973 0,038669 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01513973 0,03862799 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01513973 0,03858707 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01513973 0,03854624 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01513973 0,03850549 ! segment specification GO:0007379 13 9 0,000 0,01513973 0,03846483 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01513973 0,03842426 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01513973 0,03838377 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01513973 0,03834337 ! response to amine stimulus GO:0014075 13 9 0,000 0,01513973 0,03830305 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01513973 0,03826281 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01513973 0,03822266 ! erythrocyte development GO:0048821 15 9 0,000 0,01513973 0,0381826 ! gas homeostasis GO:0033483 16 9 0,000 0,01513973 0,03814261 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01513973 0,03810272 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01513973 0,0380629 ! renal water homeostasis GO:0003091 14 9 0,000 0,01513973 0,03802317 ! postreplication repair GO:0006301 22 9 0,000 0,01513973 0,03798352 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01513973 0,03794396 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01513973 0,03790447 ! icosanoid secretion GO:0032309 15 9 0,000 0,01513973 0,03786507 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01513973 0,03782575 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01513973 0,03778651 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01513973 0,03774735 ! regulation of cell division GO:0051302 15 9 0,000 0,01513973 0,03770828 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01513973 0,03766928 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01513973 0,03763037 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01513973 0,03759153 ! sterol catabolic process GO:0016127 11 9 0,000 0,01513973 0,03755278 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01513973 0,03751411 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01513973 0,03747551 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01513973 0,037437 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01513973 0,03739856 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01513973 0,0373602 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01513973 0,03732192 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01513973 0,03728372 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01513973 0,0372456 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01513973 0,03720756 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01513973 0,03716959 ! purine base metabolic process GO:0006144 21 9 0,000 0,01513973 0,0371317 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01513973 0,03709389 ! pigment granule transport GO:0051904 17 9 0,000 0,01513973 0,03705615 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01513973 0,03701849 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01513973 0,03698091 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01513973 0,0369434 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01513973 0,03690597 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01513973 0,03686862 ! mitochondrion localization GO:0051646 15 9 0,000 0,01513973 0,03683134 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01680799 0,04084851 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01680799 0,04080729 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01680799 0,04076615 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01680799 0,0407251 ! synapsis GO:0007129 13 10 0,000 0,01680799 0,04068413 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01680799 0,04064324 ! N-glycan processing GO:0006491 20 10 0,000 0,01680799 0,04060243 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01680799 0,04056171 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01680799 0,04052106 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01680799 0,0404805 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01680799 0,04044002 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01680799 0,04039962 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,01680799 0,0403593 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01680799 0,04031907 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01680799 0,04027891 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01680799 0,04023883 ! androgen metabolic process GO:0008209 17 10 0,000 0,01680799 0,04019883 ! phospholipid efflux GO:0033700 16 10 0,000 0,01680799 0,04015891 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01680799 0,04011907 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01680799 0,04007931 ! lung alveolus development GO:0048286 26 10 0,000 0,01680799 0,04003963 ! pathogenesis GO:0009405 13 10 0,000 0,01680799 0,04000002 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01680799 0,0399605 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01680799 0,03992105 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01680799 0,03988168 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01680799 0,03984239 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01680799 0,03980317 ! endoderm development GO:0007492 16 10 0,000 0,01680799 0,03976403 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01680799 0,03972497 ! arginine catabolic process GO:0006527 13 10 0,000 0,01680799 0,03968599 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01680799 0,03964708 ! proline metabolic process GO:0006560 13 10 0,000 0,01680799 0,03960825 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01680799 0,03956949 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01680799 0,03953081 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01680799 0,03949221 ! V(D)J recombination GO:0033151 28 10 0,000 0,01680799 0,03945368 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01680799 0,03941523 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01680799 0,03937685 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01680799 0,03933854 ! B cell proliferation GO:0042100 18 10 0,000 0,01680799 0,03930031 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01680799 0,03926216 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01680799 0,03922408 ! multicellular organism growth GO:0035264 18 10 0,000 0,01680799 0,03918607 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01680799 0,03914813 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01680799 0,03911027 ! epithelial cell development GO:0002064 20 10 0,000 0,01680799 0,03907249 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01680799 0,03903477 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01680799 0,03899713 ! macroautophagy GO:0016236 17 10 0,000 0,01680799 0,03895956 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01680799 0,03892206 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01680799 0,03888464 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01680799 0,03884728 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01680799 0,03881 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01680799 0,03877279 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01680799 0,03873565 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01680799 0,03869859 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01680799 0,03866159 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01680799 0,03862466 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01680799 0,03858781 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01680799 0,03855102 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01680799 0,03851431 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01680799 0,03847766 ! response to dsRNA GO:0043331 20 10 0,000 0,01680799 0,03844109 ! DNA ligation GO:0006266 19 10 0,000 0,01680799 0,03840458 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01680799 0,03836814 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01680799 0,03833178 ! melanosome localization GO:0032400 16 10 0,000 0,01680799 0,03829548 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01680799 0,03825925 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01680799 0,03822308 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01680799 0,03818699 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01680799 0,03815096 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01680799 0,03811501 ! mRNA cleavage GO:0006379 17 10 0,000 0,01680799 0,03807912 ! protein sumoylation GO:0016925 15 10 0,000 0,01680799 0,0380433 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01680799 0,03800754 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01680799 0,03797185 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01680799 0,03793623 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01680799 0,03790068 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01680799 0,03786519 ! salivary gland development GO:0007431 27 10 0,000 0,01680799 0,03782977 ! prophase GO:0051324 15 10 0,000 0,01680799 0,03779441 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01680799 0,03775912 ! apical protein localization GO:0045176 15 10 0,000 0,01680799 0,0377239 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01680799 0,03768874 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01680799 0,03765365 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01680799 0,03761863 ! midbrain development GO:0030901 13 10 0,000 0,01680799 0,03758366 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01680799 0,03754877 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01680799 0,03751394 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01680799 0,03747917 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01680799 0,03744447 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01680799 0,03740983 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01680799 0,03737525 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01680799 0,03734074 ! detection of calcium ion GO:0005513 23 10 0,000 0,01680799 0,03730629 ! oocyte development GO:0048599 17 10 0,000 0,01680799 0,03727191 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01680799 0,03723759 ! blastocyst formation GO:0001825 17 10 0,000 0,01680799 0,03720333 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01680799 0,03716914 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01680799 0,03713501 ! activation of innate immune response GO:0002218 12 10 0,000 0,01680799 0,03710094 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01680799 0,03706693 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01680799 0,03703299 ! response to nicotine GO:0035094 20 10 0,000 0,01680799 0,03699911 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01680799 0,03696529 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01680799 0,03693153 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01680799 0,03689783 ! localization within membrane GO:0051668 20 10 0,000 0,01680799 0,0368642 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01847348 0,04048013 ! respiratory burst GO:0045730 17 11 0,000 0,01847348 0,0404433 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01847348 0,04040653 ! neuron fate specification GO:0048665 17 11 0,000 0,01847348 0,04036983 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01847348 0,0403332 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01847348 0,04029663 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01847348 0,04026013 ! thyroid gland development GO:0030878 26 11 0,000 0,01847348 0,04022369 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,01847348 0,04018733 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01847348 0,04015102 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01847348 0,04011479 ! response to pain GO:0048265 24 11 0,000 0,01847348 0,04007861 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01847348 0,04004251 ! T cell proliferation GO:0042098 26 11 0,000 0,01847348 0,04000646 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01847348 0,03997049 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01847348 0,03993458 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01847348 0,03989873 ! bone resorption GO:0045453 16 11 0,000 0,01847348 0,03986294 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01847348 0,03982722 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01847348 0,03979157 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01847348 0,03975598 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01847348 0,03972045 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01847348 0,03968498 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01847348 0,03964958 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01847348 0,03961424 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01847348 0,03957897 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01847348 0,03954376 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01847348 0,03950861 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,01847348 0,03947352 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01847348 0,03943849 ! UV protection GO:0009650 19 11 0,000 0,01847348 0,03940353 ! adult heart development GO:0007512 14 11 0,000 0,01847348 0,03936863 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01847348 0,03933379 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01847348 0,03929901 ! temperature homeostasis GO:0001659 17 11 0,000 0,01847348 0,0392643 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01847348 0,03922964 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01847348 0,03919505 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01847348 0,03916051 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01847348 0,03912604 ! regulation of organ growth GO:0046620 13 11 0,000 0,01847348 0,03909163 ! pigment granule localization GO:0051875 20 11 0,000 0,01847348 0,03905728 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01847348 0,03902299 ! vasoconstriction GO:0042310 18 11 0,000 0,01847348 0,03898876 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01847348 0,03895459 ! embryonic axis specification GO:0000578 18 11 0,000 0,01847348 0,03892048 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01847348 0,03888642 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01847348 0,03885243 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01847348 0,0388185 ! DNA methylation GO:0006306 19 11 0,000 0,01847348 0,03878463 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01847348 0,03875081 ! zymogen activation GO:0031638 15 11 0,000 0,01847348 0,03871706 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01847348 0,03868336 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01847348 0,03864972 ! nucleosome positioning GO:0016584 15 11 0,000 0,01847348 0,03861614 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01847348 0,03858262 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01847348 0,03854916 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01847348 0,03851576 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01847348 0,03848241 ! acid secretion GO:0046717 18 11 0,000 0,01847348 0,03844912 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01847348 0,03841589 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01847348 0,03838271 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01847348 0,0383496 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01847348 0,03831654 ! oocyte differentiation GO:0009994 18 11 0,000 0,01847348 0,03828353 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01847348 0,03825059 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01847348 0,0382177 ! cholesterol efflux GO:0033344 19 11 0,000 0,01847348 0,03818486 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01847348 0,03815209 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01847348 0,03811937 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01847348 0,0380867 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01847348 0,03805409 ! embryonic gut development GO:0048566 15 11 0,000 0,01847348 0,03802154 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01847348 0,03798904 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01847348 0,0379566 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01847348 0,03792422 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01847348 0,03789189 ! defense response to fungus GO:0050832 13 11 0,000 0,01847348 0,03785961 ! developmental induction GO:0031128 19 11 0,000 0,01847348 0,03782739 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01847348 0,03779522 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01847348 0,03776311 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01847348 0,03773105 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01847348 0,03769905 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01847348 0,0376671 ! nucleus localization GO:0051647 19 11 0,000 0,01847348 0,03763521 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01847348 0,03760337 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0201362 0,04095324 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0201362 0,04091865 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0201362 0,04088412 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0201362 0,04084965 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0201362 0,04081524 ! cartilage condensation GO:0001502 20 12 0,000 0,0201362 0,04078088 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,0201362 0,04074658 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0201362 0,04071234 ! protein complex disassembly GO:0043241 27 12 0,000 0,0201362 0,04067816 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0201362 0,04064403 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,0201362 0,04060996 ! hippocampus development GO:0021766 26 12 0,000 0,0201362 0,04057595 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0201362 0,040542 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0201362 0,0405081 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0201362 0,04047426 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0201362 0,04044047 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0201362 0,04040674 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0201362 0,04037307 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0201362 0,04033946 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0201362 0,0403059 ! drug transport GO:0015893 16 12 0,000 0,0201362 0,04027239 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0201362 0,04023894 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0201362 0,04020555 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0201362 0,04017221 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0201362 0,04013893 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0201362 0,0401057 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0201362 0,04007253 ! forebrain cell migration GO:0021885 21 12 0,000 0,0201362 0,04003941 ! asymmetric protein localization GO:0008105 20 12 0,000 0,0201362 0,04000635 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0201362 0,03997334 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0201362 0,03994039 ! entry into host cell GO:0030260 32 12 0,000 0,0201362 0,03990749 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,0201362 0,03987464 ! monoamine transport GO:0015844 18 12 0,000 0,0201362 0,03984185 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0201362 0,03980911 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0201362 0,03977643 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0201362 0,0397438 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0201362 0,03971122 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0201362 0,0396787 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0201362 0,03964623 ! protein homotetramerization GO:0051289 21 12 0,000 0,0201362 0,03961381 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0201362 0,03958144 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0201362 0,03954913 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0201362 0,03951687 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0201362 0,03948467 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0201362 0,03945251 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0201362 0,03942041 ! cranial nerve development GO:0021545 20 12 0,000 0,0201362 0,03938836 ! fucose catabolic process GO:0019317 22 12 0,000 0,0201362 0,03935637 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0201362 0,03932442 ! histone acetylation GO:0016573 26 12 0,000 0,0201362 0,03929253 ! histone methylation GO:0016571 26 12 0,000 0,0201362 0,03926069 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0201362 0,0392289 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0201362 0,03919716 ! gland morphogenesis GO:0022612 29 12 0,000 0,0201362 0,03916547 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,0201362 0,03913383 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,0201362 0,03910225 ! T cell homeostasis GO:0043029 25 12 0,000 0,0201362 0,03907072 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0201362 0,03903923 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0201362 0,0390078 ! spleen development GO:0048536 22 12 0,000 0,0201362 0,03897642 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0201362 0,03894509 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0201362 0,0389138 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0201362 0,03888257 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0201362 0,03885139 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0201362 0,03882026 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0201362 0,03878918 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,0201362 0,03875815 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0201362 0,03872717 ! response to cold GO:0009409 17 12 0,000 0,0201362 0,03869624 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0201362 0,03866535 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0201362 0,03863452 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02179615 0,04178609 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02179615 0,04175282 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02179615 0,04171961 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02179615 0,04168644 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02179615 0,04165333 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02179615 0,04162028 ! lipid localization GO:0010876 28 13 0,000 0,02179615 0,04158727 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02179615 0,04155432 ! organelle fusion GO:0048284 32 13 0,000 0,02179615 0,04152142 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02179615 0,04148857 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02179615 0,04145577 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02179615 0,04142302 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02179615 0,04139033 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02179615 0,04135769 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02179615 0,0413251 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02179615 0,04129256 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02179615 0,04126007 ! methionine metabolic process GO:0006555 27 13 0,000 0,02179615 0,04122763 ! plasma membrane organization GO:0007009 24 13 0,000 0,02179615 0,04119525 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02179615 0,04116291 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02179615 0,04113063 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02179615 0,04109839 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02179615 0,04106621 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02179615 0,04103407 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02179615 0,04100199 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02179615 0,04096996 ! exocrine system development GO:0035272 32 13 0,000 0,02179615 0,04093798 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02179615 0,04090604 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02179615 0,04087416 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02179615 0,04084233 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02179615 0,04081054 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02179615 0,04077881 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02179615 0,04074712 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02179615 0,04071549 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02179615 0,0406839 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02179615 0,04065236 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02179615 0,04062087 ! ribosome assembly GO:0042255 17 13 0,000 0,02179615 0,04058943 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02179615 0,04055804 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02179615 0,0405267 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02179615 0,0404954 ! chromatin silencing GO:0006342 26 13 0,000 0,02179615 0,04046416 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02179615 0,04043296 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02179615 0,04040181 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02179615 0,04037071 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02179615 0,04033965 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02179615 0,04030865 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02179615 0,04027769 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02179615 0,04024677 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02179615 0,04021591 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02179615 0,04018509 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02179615 0,04015432 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02179615 0,0401236 ! embryonic placenta development GO:0001892 23 13 0,000 0,02179615 0,04009293 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02179615 0,0400623 ! insulin secretion GO:0030073 23 13 0,000 0,02179615 0,04003172 ! actin filament polymerization GO:0030041 24 13 0,000 0,02179615 0,04000118 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02179615 0,03997069 ! acrosome reaction GO:0007340 18 13 0,000 0,02179615 0,03994025 ! rRNA transcription GO:0009303 25 14 0,000 0,02345336 0,04294427 ! lactation GO:0007595 26 14 0,000 0,02345336 0,04291162 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02345336 0,04287901 ! reproductive cellular process GO:0048610 20 14 0,000 0,02345336 0,04284645 ! tRNA modification GO:0006400 20 14 0,000 0,02345336 0,04281394 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02345336 0,04278148 ! regulation of S phase GO:0033261 23 14 0,000 0,02345336 0,04274907 ! water transport GO:0006833 21 14 0,000 0,02345336 0,04271671 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02345336 0,0426844 ! non-recombinational repair GO:0000726 25 14 0,000 0,02345336 0,04265213 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02345336 0,04261992 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02345336 0,04258775 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02345336 0,04255564 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02345336 0,04252357 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02345336 0,04249155 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02345336 0,04245957 ! palate development GO:0060021 31 14 0,000 0,02345336 0,04242765 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02345336 0,04239577 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02345336 0,04236394 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02345336 0,04233216 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02345336 0,04230043 ! arginine metabolic process GO:0006525 17 14 0,000 0,02345336 0,04226874 ! regulation of heart rate GO:0002027 24 14 0,000 0,02345336 0,04223711 ! organic alcohol transport GO:0015850 29 14 0,000 0,02345336 0,04220552 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02345336 0,04217397 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02345336 0,04214248 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02345336 0,04211103 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02345336 0,04207962 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02345336 0,04204827 ! L-amino acid transport GO:0015807 30 14 0,000 0,02345336 0,04201696 ! bone mineralization GO:0030282 17 14 0,000 0,02345336 0,0419857 ! stem cell development GO:0048864 43 14 0,000 0,02345336 0,04195448 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02345336 0,04192331 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02345336 0,04189219 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02345336 0,04186111 ! cerebellum development GO:0021549 21 14 0,000 0,02345336 0,04183008 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02345336 0,04179909 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02345336 0,04176815 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02345336 0,04173726 ! cofactor transport GO:0051181 26 14 0,000 0,02345336 0,04170641 ! NADP metabolic process GO:0006739 24 14 0,000 0,02345336 0,04167561 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02345336 0,04164485 ! intestinal absorption GO:0050892 25 14 0,000 0,02345336 0,04161414 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02345336 0,04158347 ! oxygen transport GO:0015671 21 14 0,000 0,02345336 0,04155285 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02345336 0,04152228 ! male genitalia development GO:0030539 24 14 0,000 0,02345336 0,04149175 ! regulation of axon extension GO:0030516 37 14 0,000 0,02345336 0,04146126 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02345336 0,04143082 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02510781 0,04432089 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02510781 0,0442884 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02510781 0,04425596 ! superoxide anion generation GO:0042554 20 15 0,000 0,02510781 0,04422356 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02510781 0,04419121 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02510781 0,0441589 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02510781 0,04412665 ! copper ion transport GO:0006825 20 15 0,000 0,02510781 0,04409444 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,02510781 0,04406227 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02510781 0,04403016 ! sulfate transport GO:0008272 23 15 0,000 0,02510781 0,04399809 ! response to cAMP GO:0051591 22 15 0,000 0,02510781 0,04396607 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02510781 0,04393409 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02510781 0,04390216 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02510781 0,04387028 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02510781 0,04383845 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02510781 0,04380666 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02510781 0,04377491 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02510781 0,04374321 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02510781 0,04371156 ! pituitary gland development GO:0021983 29 15 0,000 0,02510781 0,04367996 ! vesicle coating GO:0006901 33 15 0,000 0,02510781 0,0436484 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02510781 0,04361688 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02510781 0,04358541 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02510781 0,04355399 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02510781 0,04352261 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02510781 0,04349127 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02510781 0,04345998 ! regulation of vasodilation GO:0042312 26 15 0,000 0,02510781 0,04342874 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02510781 0,04339754 ! histone deacetylation GO:0016575 20 15 0,000 0,02510781 0,04336639 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02510781 0,04333528 ! tissue regeneration GO:0042246 26 15 0,000 0,02510781 0,04330421 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02510781 0,04327319 ! water homeostasis GO:0030104 27 15 0,000 0,02510781 0,04324222 ! muscle maintenance GO:0046716 26 15 0,000 0,02510781 0,04321129 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02510781 0,0431804 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02510781 0,04314956 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02510781 0,04311876 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02510781 0,043088 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02510781 0,04305729 ! cell killing GO:0001906 29 15 0,000 0,02510781 0,04302662 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02510781 0,042996 ! detection of bacterium GO:0016045 18 15 0,000 0,02510781 0,04296542 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02510781 0,04293488 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02510781 0,04290439 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02510781 0,04287394 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02510781 0,04284353 ! peptide hormone processing GO:0016486 23 15 0,000 0,02510781 0,04281317 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02675951 0,04559729 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02675951 0,04556502 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02675951 0,04553279 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02675951 0,04550062 ! bone remodeling GO:0046849 27 16 0,000 0,02675951 0,04546848 ! filopodium assembly GO:0046847 32 16 0,000 0,02675951 0,04543639 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02675951 0,04540435 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02675951 0,04537235 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02675951 0,0453404 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02675951 0,04530849 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02675951 0,04527663 ! startle response GO:0001964 28 16 0,000 0,02675951 0,04524481 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02675951 0,04521304 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,02675951 0,04518131 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02675951 0,04514963 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02675951 0,04511799 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02675951 0,04508639 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02675951 0,04505484 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02675951 0,04502334 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02675951 0,04499187 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02675951 0,04496045 ! response to osmotic stress GO:0006970 25 16 0,000 0,02675951 0,04492908 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02675951 0,04489775 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02675951 0,04486646 ! fructose metabolic process GO:0006000 25 16 0,000 0,02675951 0,04483522 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02675951 0,04480402 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02675951 0,04477286 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02675951 0,04474175 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02675951 0,04471067 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02675951 0,04467965 ! axon cargo transport GO:0008088 43 16 0,000 0,02675951 0,04464866 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02675951 0,04461772 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02675951 0,04458682 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,02675951 0,04455597 ! DNA replication initiation GO:0006270 27 16 0,000 0,02675951 0,04452515 ! neuron recognition GO:0008038 35 16 0,000 0,02675951 0,04449438 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02675951 0,04446365 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02675951 0,04443297 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02675951 0,04440233 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02675951 0,04437172 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02675951 0,04434116 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02675951 0,04431065 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02675951 0,04428017 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02675951 0,04424974 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02675951 0,04421935 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02675951 0,044189 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02675951 0,04415869 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,02675951 0,04412842 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02840846 0,04681559 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,02840846 0,04678355 ! metencephalon development GO:0022037 30 17 0,000 0,02840846 0,04675155 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02840846 0,04671959 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02840846 0,04668768 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02840846 0,04665581 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02840846 0,04662399 ! signal complex assembly GO:0007172 41 17 0,000 0,02840846 0,0465922 ! endothelial cell migration GO:0043542 28 17 0,000 0,02840846 0,04656047 ! inositol metabolic process GO:0006020 28 17 0,000 0,02840846 0,04652877 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02840846 0,04649712 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02840846 0,04646551 ! glial cell development GO:0021782 27 17 0,000 0,02840846 0,04643394 ! limbic system development GO:0021761 36 17 0,000 0,02840846 0,04640242 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02840846 0,04637094 ! adult walking behavior GO:0007628 33 17 0,000 0,02840846 0,0463395 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02840846 0,0463081 ! heart looping GO:0001947 30 17 0,000 0,02840846 0,04627675 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02840846 0,04624544 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02840846 0,04621417 ! myoblast differentiation GO:0045445 45 17 0,000 0,02840846 0,04618295 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02840846 0,04615176 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02840846 0,04612062 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02840846 0,04608952 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02840846 0,04605847 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02840846 0,04602745 ! glycine metabolic process GO:0006544 28 17 0,000 0,02840846 0,04599648 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02840846 0,04596554 ! NAD metabolic process GO:0019674 29 17 0,000 0,02840846 0,04593465 ! membrane budding GO:0006900 37 17 0,000 0,02840846 0,0459038 ! DNA integration GO:0015074 29 17 0,000 0,02840846 0,045873 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02840846 0,04584223 ! regulation of protein binding GO:0043393 33 17 0,000 0,02840846 0,0458115 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02840846 0,04578082 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02840846 0,04575018 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02840846 0,04571957 ! genitalia development GO:0048806 30 17 0,000 0,02840846 0,04568901 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02840846 0,04565849 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02840846 0,04562801 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02840846 0,04559757 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02840846 0,04556718 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02840846 0,04553682 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02840846 0,0455065 ! steroid catabolic process GO:0006706 31 17 0,000 0,02840846 0,04547622 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02840846 0,04544599 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02840846 0,04541579 ! gas transport GO:0015669 25 17 0,000 0,02840846 0,04538563 ! organic cation transport GO:0015695 31 17 0,000 0,02840846 0,04535552 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02840846 0,04532544 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02840846 0,0452954 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02840846 0,04526541 ! microspike assembly GO:0030035 36 17 0,000 0,02840846 0,04523545 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02840846 0,04520553 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02840846 0,04517565 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03005468 0,04776193 ! neuron maturation GO:0042551 42 18 0,000 0,03005468 0,04773041 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03005468 0,04769892 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03005468 0,04766748 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,03005468 0,04763608 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03005468 0,04760472 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03005468 0,0475734 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03005468 0,04754212 ! memory GO:0007613 31 18 0,000 0,03005468 0,04751088 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03005468 0,04747969 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03005468 0,04744853 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03005468 0,04741742 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03005468 0,04738635 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03005468 0,04735531 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03005468 0,04732432 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03005468 0,04729337 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03005468 0,04726246 ! response to retinoic acid GO:0032526 26 18 0,000 0,03005468 0,04723159 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03005468 0,04720076 ! response to fungus GO:0009620 21 18 0,000 0,03005468 0,04716997 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03005468 0,04713922 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03005468 0,04710851 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03005468 0,04707784 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03005468 0,04704721 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03005468 0,04701662 ! vitamin transport GO:0051180 27 18 0,000 0,03005468 0,04698607 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03005468 0,04695556 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03005468 0,04692509 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03005468 0,04689466 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03005468 0,04686427 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03005468 0,04683391 ! nerve development GO:0021675 28 18 0,000 0,03005468 0,0468036 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03005468 0,04677333 ! protein secretion GO:0009306 39 19 0,000 0,03169817 0,04929915 ! positive regulation of translation GO:0045727 30 19 0,000 0,03169817 0,0492673 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03169817 0,0492355 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03169817 0,04920373 ! skin development GO:0043588 36 19 0,000 0,03169817 0,04917201 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03169817 0,04914033 ! lipid phosphorylation GO:0046834 35 19 0,000 0,03169817 0,04910868 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03169817 0,04907708 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03169817 0,04904552 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03169817 0,049014 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03169817 0,04898252 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03169817 0,04895108 ! cerebral cortex development GO:0021987 36 19 0,000 0,03169817 0,04891968 ! pigmentation during development GO:0048066 41 19 0,000 0,03169817 0,04888832 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03169817 0,04885701 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03169817 0,04882573 ! heme metabolic process GO:0042168 36 19 0,000 0,03169817 0,04879449 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03169817 0,04876329 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03169817 0,04873213 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03169817 0,04870101 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03169817 0,04866993 ! peptide cross-linking GO:0018149 37 19 0,000 0,03169817 0,04863889 ! protein export from nucleus GO:0006611 36 19 0,000 0,03169817 0,04860789 ! heart process GO:0003015 30 19 0,000 0,03169817 0,04857693 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03169817 0,04854601 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,03169817 0,04851513 ! visual learning GO:0008542 36 19 0,000 0,03169817 0,04848429 ! cellular pigmentation GO:0033059 36 19 0,000 0,03169817 0,04845348 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03169817 0,04842272 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03169817 0,048392 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03169817 0,04836131 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03169817 0,04833066 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03169817 0,04830005 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03169817 0,04826948 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03169817 0,04823895 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03169817 0,04820846 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03169817 0,04817801 ! cilium assembly GO:0042384 37 19 0,000 0,03169817 0,04814759 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03169817 0,04811721 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03333892 0,05057594 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03333892 0,05054407 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03333892 0,05051224 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03333892 0,05048045 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03333892 0,0504487 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03333892 0,05041699 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,03333892 0,05038533 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03333892 0,0503537 ! response to vitamin GO:0033273 31 20 0,000 0,03333892 0,05032211 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03333892 0,05029056 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03333892 0,05025905 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03333892 0,05022758 ! response to alkaloid GO:0043279 38 20 0,000 0,03333892 0,05019614 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03333892 0,05016475 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03333892 0,0501334 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03333892 0,05010208 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03333892 0,05007081 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03333892 0,05003957 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03333892 0,05000838 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03333892 0,04997722 ! body fluid secretion GO:0007589 31 20 0,000 0,03333892 0,0499461 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03333892 0,04991502 ! peptide secretion GO:0002790 35 20 0,000 0,03333892 0,04988398 ! stem cell differentiation GO:0048863 53 20 0,000 0,03333892 0,04985298 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03333892 0,04982201 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,03333892 0,04979108 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03333892 0,0497602 ! sensory perception of pain GO:0019233 30 20 0,000 0,03333892 0,04972935 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03333892 0,04969854 ! diencephalon development GO:0021536 34 20 0,000 0,03333892 0,04966776 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03333892 0,04963703 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03333892 0,04960633 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03333892 0,04957567 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03333892 0,04954505 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03333892 0,04951447 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03333892 0,04948392 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03333892 0,04945341 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,03333892 0,04942294 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03333892 0,04939251 ! regulation of glucose import GO:0046324 29 20 0,000 0,03333892 0,04936212 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03333892 0,04933176 ! actin filament-based movement GO:0030048 43 20 0,000 0,03333892 0,04930144 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03333892 0,04927115 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03333892 0,04924091 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03333892 0,0492107 ! negative regulation of translation GO:0017148 29 20 0,000 0,03333892 0,04918053 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03333892 0,04915039 ! regulation of cell killing GO:0031341 42 21 0,000 0,03497695 0,0515337 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03497695 0,05150216 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03497695 0,05147066 ! hormone secretion GO:0046879 38 21 0,000 0,03497695 0,0514392 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03497695 0,05140778 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03497695 0,05137639 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03497695 0,05134505 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03497695 0,05131374 ! axis specification GO:0009798 38 21 0,000 0,03497695 0,05128247 ! ovarian follicle development GO:0001541 35 21 0,000 0,03497695 0,05125124 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,03497695 0,05122004 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03497695 0,05118889 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03497695 0,05115777 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03497695 0,05112669 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03497695 0,05109565 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03497695 0,05106464 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03497695 0,05103368 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,03497695 0,05100275 ! cytolysis GO:0019835 24 21 0,000 0,03497695 0,05097185 ! vasodilation GO:0042311 39 21 0,000 0,03497695 0,050941 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03497695 0,05091018 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,03497695 0,0508794 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03497695 0,05084866 ! oogenesis GO:0048477 36 21 0,000 0,03497695 0,05081795 ! DNA modification GO:0006304 34 21 0,000 0,03497695 0,05078729 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03497695 0,05075665 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03497695 0,05072606 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03497695 0,0506955 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03497695 0,05066498 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03497695 0,0506345 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03497695 0,05060405 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03497695 0,05057364 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03497695 0,05054326 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03497695 0,05051292 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03497695 0,05048262 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03497695 0,05045236 ! collagen catabolic process GO:0030574 28 21 0,000 0,03497695 0,05042213 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03497695 0,05039194 ! gut development GO:0048565 39 21 0,000 0,03497695 0,05036178 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03661225 0,05268486 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03661225 0,05265336 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03661225 0,05262191 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03661225 0,05259049 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03661225 0,05255912 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03661225 0,05252778 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03661225 0,05249647 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03661225 0,0524652 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03661225 0,05243398 ! regeneration GO:0031099 41 22 0,000 0,03661225 0,05240278 ! keratinization GO:0031424 28 22 0,000 0,03661225 0,05237163 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03661225 0,05234051 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03661225 0,05230943 ! sensory perception of taste GO:0050909 28 22 0,000 0,03661225 0,05227839 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,03661225 0,05224738 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03661225 0,05221641 ! vacuolar transport GO:0007034 36 22 0,000 0,03661225 0,05218547 ! lysosome organization GO:0007040 41 22 0,000 0,03661225 0,05215458 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03661225 0,05212372 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03661225 0,05209289 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,03661225 0,0520621 ! fucose metabolic process GO:0006004 39 22 0,000 0,03661225 0,05203135 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03661225 0,05200064 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03661225 0,05196996 ! ureteric bud development GO:0001657 43 22 0,000 0,03661225 0,05193932 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03661225 0,05190871 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03661225 0,05187814 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03661225 0,0518476 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,03661225 0,05181711 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03661225 0,05178664 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03661225 0,05175622 ! sarcomere organization GO:0045214 30 22 0,000 0,03661225 0,05172582 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03661225 0,05169547 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03661225 0,05166515 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03661225 0,05163486 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03661225 0,05160462 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,03661225 0,0515744 ! protein stabilization GO:0050821 39 22 0,000 0,03661225 0,05154422 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03824484 0,05381116 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03824484 0,05377971 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03824484 0,0537483 ! gluconeogenesis GO:0006094 33 23 0,000 0,03824484 0,05371692 ! viral genome replication GO:0019079 41 23 0,000 0,03824484 0,05368558 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03824484 0,05365428 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03824484 0,05362301 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03824484 0,05359178 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03824484 0,05356059 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,03824484 0,05352943 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03824484 0,05349831 ! visual behavior GO:0007632 42 23 0,000 0,03824484 0,05346722 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03824484 0,05343617 ! response to ethanol GO:0045471 46 23 0,000 0,03824484 0,05340516 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03824484 0,05337418 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03824484 0,05334324 ! peroxisome organization GO:0007031 37 23 0,000 0,03824484 0,05331233 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03824484 0,05328146 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03824484 0,05325063 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,03824484 0,05321983 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03824484 0,05318907 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03824484 0,05315834 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03824484 0,05312765 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03824484 0,05309699 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03824484 0,05306637 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03824484 0,05303579 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03824484 0,05300524 ! fatty acid transport GO:0015908 44 23 0,000 0,03824484 0,05297472 ! platelet activation GO:0030168 37 23 0,000 0,03824484 0,05294424 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03824484 0,05291379 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03824484 0,05288338 ! hormone transport GO:0009914 40 23 0,000 0,03824484 0,05285301 ! cell-cell recognition GO:0009988 25 23 0,000 0,03824484 0,05282267 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03824484 0,05279236 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03824484 0,05276209 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03824484 0,05273186 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03824484 0,05270165 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03824484 0,05267149 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03987472 0,05488477 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03987472 0,05485339 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03987472 0,05482204 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03987472 0,05479073 ! vesicle docking GO:0048278 47 24 0,000 0,03987472 0,05475946 ! spinal cord development GO:0021510 47 24 0,000 0,03987472 0,05472822 ! vacuole organization GO:0007033 43 24 0,000 0,03987472 0,05469702 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03987472 0,05466585 ! digestive system process GO:0022600 39 24 0,000 0,03987472 0,05463472 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03987472 0,05460363 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03987472 0,05457257 ! regulation of behavior GO:0050795 43 24 0,000 0,03987472 0,05454154 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03987472 0,05451055 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03987472 0,0544796 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03987472 0,05444868 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03987472 0,05441779 ! membrane depolarization GO:0051899 39 24 0,000 0,03987472 0,05438695 ! pallium development GO:0021543 49 24 0,000 0,03987472 0,05435613 ! pentose metabolic process GO:0019321 35 24 0,000 0,03987472 0,05432535 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,03987472 0,05429461 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03987472 0,0542639 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03987472 0,05423322 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03987472 0,05420258 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03987472 0,05417198 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03987472 0,05414141 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03987472 0,05411087 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03987472 0,05408037 ! regulation of amine transport GO:0051952 40 24 0,000 0,03987472 0,0540499 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04150189 0,05622384 ! myelination GO:0042552 45 25 0,000 0,04150189 0,0561922 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04150189 0,0561606 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04150189 0,05612903 ! phototransduction GO:0007602 33 25 0,000 0,04150189 0,05609749 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,04150189 0,056066 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,04150189 0,05603453 ! sperm motility GO:0030317 31 25 0,000 0,04150189 0,05600311 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,04150189 0,05597172 ! receptor metabolic process GO:0043112 46 25 0,000 0,04150189 0,05594036 ! chromosome condensation GO:0030261 45 25 0,000 0,04150189 0,05590904 ! osteoblast differentiation GO:0001649 60 25 0,000 0,04150189 0,05587775 ! neural crest cell development GO:0014032 54 25 0,000 0,04150189 0,0558465 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04150189 0,05581528 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04150189 0,0557841 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04150189 0,05575295 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04150189 0,05572184 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,04150189 0,05569076 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04150189 0,05565972 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04150189 0,05562871 ! immunoglobulin production GO:0002377 55 25 0,000 0,04150189 0,05559774 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04150189 0,0555668 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04150189 0,0555359 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,04150189 0,05550503 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04150189 0,05547419 ! telomere organization GO:0032200 43 25 0,000 0,04150189 0,05544339 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04150189 0,05541262 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04150189 0,05538189 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,04312635 0,05751774 ! embryonic pattern specification GO:0009880 44 26 0,000 0,04312635 0,05748587 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,04312635 0,05745404 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,04312635 0,05742225 ! initiation of viral infection GO:0019059 57 26 0,000 0,04312635 0,05739049 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,04312635 0,05735876 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,04312635 0,05732707 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,04312635 0,05729542 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,04312635 0,0572638 ! molting cycle process GO:0022404 50 26 0,000 0,04312635 0,05723221 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,04312635 0,05720066 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,04312635 0,05716915 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,04312635 0,05713767 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,04312635 0,05710622 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,04312635 0,05707481 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,04312635 0,05704343 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,04312635 0,05701209 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,04312635 0,05698078 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,04312635 0,05694951 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,04312635 0,05691827 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,04312635 0,05688706 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,04312635 0,05685589 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,04312635 0,05682476 ! blastocyst development GO:0001824 49 26 0,000 0,04312635 0,05679365 ! leukocyte proliferation GO:0070661 52 26 0,000 0,04312635 0,05676258 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,04312635 0,05673155 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,04312635 0,05670055 ! neuron fate commitment GO:0048663 48 27 0,000 0,04474812 0,05880064 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04474812 0,05876854 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04474812 0,05873648 ! iron ion transport GO:0006826 59 27 0,000 0,04474812 0,05870446 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,04474812 0,05867246 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04474812 0,05864051 ! protein amino acid acylation GO:0043543 55 27 0,000 0,04474812 0,05860859 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04474812 0,0585767 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04474812 0,05854485 ! fat cell differentiation GO:0045444 50 27 0,000 0,04474812 0,05851303 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04474812 0,05848124 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04474812 0,0584495 ! autophagy GO:0006914 41 27 0,000 0,04474812 0,05841778 ! male gonad development GO:0008584 44 27 0,000 0,04474812 0,0583861 ! primary neural tube formation GO:0014020 51 27 0,000 0,04474812 0,05835446 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04474812 0,05832285 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04474812 0,05829127 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04474812 0,05825973 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04474812 0,05822822 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04474812 0,05819674 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04474812 0,0581653 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04474812 0,05813389 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04474812 0,05810252 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04636719 0,06017231 ! circadian rhythm GO:0007623 50 28 0,000 0,04636719 0,06013987 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04636719 0,06010747 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04636719 0,0600751 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04636719 0,06004276 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04636719 0,06001047 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04636719 0,0599782 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04636719 0,05994597 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04636719 0,05991378 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04636719 0,05988162 ! synaptogenesis GO:0007416 42 28 0,000 0,04636719 0,05984949 ! lipid oxidation GO:0034440 43 28 0,000 0,04636719 0,0598174 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04636719 0,05978535 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04636719 0,05975332 ! translational initiation GO:0006413 65 29 0,000 0,04798357 0,06180325 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,04798357 0,06177018 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,04798357 0,06173715 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,04798357 0,06170415 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,04798357 0,06167119 ! catechol metabolic process GO:0009712 54 29 0,000 0,04798357 0,06163826 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,04798357 0,06160537 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,04798357 0,06157252 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,04798357 0,0615397 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,04798357 0,06150691 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,04798357 0,06147416 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,04798357 0,06144144 ! cell fate determination GO:0001709 60 29 0,000 0,04798357 0,06140876 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,04798357 0,06137611 ! detection of light stimulus GO:0009583 38 29 0,000 0,04798357 0,0613435 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,04798357 0,06131092 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,04798357 0,06127838 ! tissue homeostasis GO:0001894 48 29 0,000 0,04798357 0,06124587 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,04798357 0,0612134 ! phenol metabolic process GO:0018958 55 30 0,000 0,04959726 0,06323848 ! zinc ion transport GO:0006829 45 30 0,000 0,04959726 0,06320499 ! membrane docking GO:0022406 61 30 0,000 0,04959726 0,06317153 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04959726 0,0631381 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04959726 0,06310472 ! acute-phase response GO:0006953 49 30 0,000 0,04959726 0,06307136 ! myofibril assembly GO:0030239 47 30 0,000 0,04959726 0,06303804 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,04959726 0,06300476 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04959726 0,06297151 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04959726 0,0629383 ! phospholipid transport GO:0015914 51 30 0,000 0,04959726 0,06290512 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04959726 0,06287198 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04959726 0,06283887 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04959726 0,0628058 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04959726 0,06277276 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04959726 0,06273976 ! eye morphogenesis GO:0048592 60 30 0,000 0,04959726 0,06270679 ! response to heat GO:0009408 50 30 0,000 0,04959726 0,06267385 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,05120828 0,06467565 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,05120828 0,06464172 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,05120828 0,06460782 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,05120828 0,06457396 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,05120828 0,06454013 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,05120828 0,06450634 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,05120828 0,06447259 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,05120828 0,06443887 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,05120828 0,06440518 ! ovulation cycle process GO:0022602 49 31 0,000 0,05120828 0,06437153 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,05120828 0,06433792 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,05120828 0,06430434 ! peptide transport GO:0015833 55 31 0,000 0,05120828 0,06427079 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,05120828 0,06423729 ! iron ion homeostasis GO:0055072 54 31 0,000 0,05120828 0,06420381 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,05120828 0,06417037 ! mesoderm formation GO:0001707 69 31 0,000 0,05120828 0,06413697 ! natural killer cell activation GO:0030101 45 31 0,000 0,05120828 0,0641036 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,05120828 0,06407026 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,05120828 0,06403696 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,05120828 0,0640037 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,05120828 0,06397046 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,05120828 0,06393727 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,05281661 0,06591119 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,05281661 0,06587702 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,05281661 0,06584289 ! cholesterol transport GO:0030301 56 32 0,000 0,05281661 0,06580879 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,05281661 0,06577472 ! spliceosome assembly GO:0000245 67 32 0,000 0,05281661 0,0657407 ! spindle organization GO:0007051 46 32 0,000 0,05281661 0,06570671 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,05281661 0,06567275 ! metanephros development GO:0001656 74 32 0,000 0,05281661 0,06563883 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,05281661 0,06560494 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,05281661 0,06557109 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,05281661 0,06553727 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,05281661 0,06550349 ! muscle cell development GO:0055001 49 32 0,000 0,05281661 0,06546974 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,05281661 0,06543603 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,05281661 0,06540235 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,05281661 0,06536871 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,05281661 0,0653351 ! ovulation cycle GO:0042698 51 32 0,000 0,05281661 0,06530153 ! peripheral nervous system development GO:0007422 64 32 0,000 0,05281661 0,06526799 ! BMP signaling pathway GO:0030509 64 32 0,000 0,05281661 0,06523448 ! hindbrain development GO:0030902 61 32 0,000 0,05281661 0,06520101 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,05281661 0,06516757 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,05281661 0,06513417 ! gene silencing GO:0016458 65 32 0,000 0,05281661 0,0651008 ! post-embryonic development GO:0009791 69 33 0,000 0,05442227 0,06704557 ! protein targeting to membrane GO:0006612 68 33 0,000 0,05442227 0,06701125 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,05442227 0,06697698 ! ceramide metabolic process GO:0006672 64 33 0,000 0,05442227 0,06694274 ! formation of primary germ layer GO:0001704 72 33 0,000 0,05442227 0,06690853 ! cell fate specification GO:0001708 52 33 0,000 0,05442227 0,06687436 ! sterol transport GO:0015918 57 33 0,000 0,05442227 0,06684022 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,05442227 0,06680612 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,05442227 0,06677205 ! adult locomotory behavior GO:0008344 59 33 0,000 0,05442227 0,06673802 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,05442227 0,06670402 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,05442227 0,06667006 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,05602527 0,06859888 ! glial cell differentiation GO:0010001 63 34 0,000 0,05602527 0,06856399 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,05602527 0,06852913 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,05602527 0,06849431 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,05602527 0,06845952 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,05602527 0,06842477 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,05602527 0,06839005 ! mismatch repair GO:0006298 46 34 0,000 0,05602527 0,06835537 ! spermatid development GO:0007286 63 34 0,000 0,05602527 0,06832073 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,05602527 0,06828612 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,05602527 0,06825154 ! placenta development GO:0001890 53 34 0,000 0,05602527 0,068217 ! regulation of muscle development GO:0048634 70 35 0,000 0,0576256 0,07013009 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,0576256 0,07009463 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0576256 0,07005922 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0576256 0,07002383 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0576256 0,06998848 ! odontogenesis GO:0042476 66 35 0,000 0,0576256 0,06995317 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0576256 0,0699179 ! female gonad development GO:0008585 58 35 0,000 0,0576256 0,06988266 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0576256 0,06984745 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0576256 0,06981228 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,0576256 0,06977715 ! cytokine production GO:0001816 59 35 0,000 0,0576256 0,06974205 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,0576256 0,06970698 ! neural tube formation GO:0001841 67 35 0,000 0,0576256 0,06967195 ! vesicle localization GO:0051648 64 35 0,000 0,0576256 0,06963696 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,05922327 0,07153172 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,05922327 0,07149583 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,05922327 0,07145997 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,05922327 0,07142415 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,05922327 0,07138837 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,05922327 0,07135262 ! positive regulation of cell development GO:0010720 80 36 0,000 0,05922327 0,07131691 ! regulation of proteolysis GO:0030162 72 36 0,000 0,05922327 0,07128123 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,05922327 0,07124559 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,05922327 0,07120999 ! aerobic respiration GO:0009060 55 36 0,000 0,05922327 0,07117442 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,05922327 0,07113888 ! embryonic organ development GO:0048568 57 36 0,000 0,05922327 0,07110338 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,05922327 0,07106792 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,05922327 0,07103249 ! RNA export from nucleus GO:0006405 56 37 0,000 0,06081828 0,07290921 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,06081828 0,0728729 ! meiosis I GO:0007127 65 37 0,000 0,06081828 0,07283663 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,06081828 0,07280039 ! sister chromatid segregation GO:0000819 58 37 0,000 0,06081828 0,07276419 ! actomyosin structure organization GO:0031032 62 37 0,000 0,06081828 0,07272802 ! organic anion transport GO:0015711 68 37 0,000 0,06081828 0,07269189 ! tissue remodeling GO:0048771 76 37 0,000 0,06081828 0,0726558 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,06081828 0,07261974 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,06081828 0,07258372 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,06081828 0,07254774 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,06081828 0,07251179 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,06081828 0,07247587 ! glycogen metabolic process GO:0005977 61 37 0,000 0,06081828 0,07243999 ! pigment metabolic process GO:0042440 80 37 0,000 0,06081828 0,07240415 ! spermatid differentiation GO:0048515 66 37 0,000 0,06081828 0,07236834 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,06241064 0,0742264 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,06241064 0,07418973 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,06241064 0,07415309 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,06241064 0,07411649 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,06241064 0,07407993 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,06241064 0,0740434 ! lipid homeostasis GO:0055088 67 38 0,000 0,06241064 0,0740069 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,06241064 0,07397045 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,06241064 0,07393403 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,06241064 0,07389764 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,06241064 0,07386129 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,06241064 0,07382498 ! glucan metabolic process GO:0044042 62 38 0,000 0,06241064 0,0737887 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,06400036 0,07563107 ! learning GO:0007612 77 39 0,000 0,06400036 0,07559394 ! ear morphogenesis GO:0042471 60 39 0,000 0,06400036 0,07555685 ! organic ether metabolic process GO:0018904 55 39 0,000 0,06400036 0,0755198 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,06400036 0,07548278 ! segmentation GO:0035282 67 39 0,000 0,06400036 0,07544579 ! ion transmembrane transport GO:0034220 66 39 0,000 0,06400036 0,07540885 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,06400036 0,07537194 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,06400036 0,07533506 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,06400036 0,07529822 ! RNA modification GO:0009451 57 39 0,000 0,06400036 0,07526142 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,06558743 0,07709006 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,06558743 0,07705242 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,06558743 0,07701482 ! feeding behavior GO:0007631 59 40 0,000 0,06558743 0,07697725 ! negative regulation of binding GO:0051100 72 40 0,000 0,06558743 0,07693972 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,06558743 0,07690222 ! mesenchymal cell development GO:0014031 87 40 0,000 0,06558743 0,07686476 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,06558743 0,07682734 ! maintenance of protein location GO:0045185 91 40 0,000 0,06558743 0,07678996 ! cytokinesis GO:0000910 72 40 0,000 0,06558743 0,07675261 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06717187 0,07856855 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06717187 0,07853038 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06717187 0,07849224 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06717187 0,07845413 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06717187 0,07841607 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06717187 0,07837804 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,06717187 0,07834004 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06717187 0,07830209 ! female gamete generation GO:0007292 61 41 0,000 0,06717187 0,07826417 ! polyol metabolic process GO:0019751 66 41 0,000 0,06717187 0,07822629 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06717187 0,07818844 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06875367 0,07999097 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06875367 0,07995231 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,06875367 0,07991368 ! regulation of tube size GO:0035150 71 42 0,000 0,06875367 0,0798751 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06875367 0,07983655 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,06875367 0,07979803 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,06875367 0,07975956 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,06875367 0,07972112 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,06875367 0,07968272 ! neuron migration GO:0001764 79 42 0,000 0,06875367 0,07964435 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06875367 0,07960603 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,07033284 0,08139529 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,07033284 0,08135616 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,07033284 0,08131706 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,07033284 0,08127801 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,07033284 0,08123899 ! glucose transport GO:0015758 65 43 0,000 0,07033284 0,0812 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,07033284 0,08116106 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,07033284 0,08112215 ! neural tube development GO:0021915 77 43 0,000 0,07033284 0,08108328 ! striated muscle contraction GO:0006941 77 43 0,000 0,07033284 0,08104445 ! phagocytosis GO:0006909 90 43 0,000 0,07033284 0,08100565 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,07033284 0,08096689 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,07190938 0,08274222 ! hexose transport GO:0008645 67 44 0,000 0,07190938 0,08270267 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,07190938 0,08266315 ! male sex differentiation GO:0046661 76 44 0,000 0,07190938 0,08262368 ! biopolymer methylation GO:0043414 84 44 0,000 0,07190938 0,08258424 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,07190938 0,08254484 ! developmental growth GO:0048589 82 44 0,000 0,07190938 0,08250547 ! maintenance of location in cell GO:0051651 97 44 0,000 0,07190938 0,08246615 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,07348331 0,08423099 ! glycolysis GO:0006096 65 45 0,000 0,07348331 0,08419088 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,07348331 0,0841508 ! leukocyte migration GO:0050900 68 45 0,000 0,07348331 0,08411077 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,07348331 0,08407077 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,07348331 0,08403082 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,07348331 0,0839909 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,07348331 0,08395102 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,07348331 0,08391117 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,07348331 0,08387137 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,07348331 0,0838316 ! cell growth GO:0016049 84 45 0,000 0,07348331 0,08379187 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,07505462 0,08554306 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,07505462 0,08550256 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,07505462 0,08546209 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,07505462 0,08542167 ! pigmentation GO:0043473 100 46 0,000 0,07505462 0,08538128 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,07505462 0,08534093 ! positive regulation of defense response GO:0031349 76 47 0,000 0,07662331 0,08708346 ! response to calcium ion GO:0051592 81 47 0,000 0,07662331 0,08704234 ! endosome transport GO:0016197 108 47 0,000 0,07662331 0,08700127 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,07662331 0,08696023 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,07662331 0,08691923 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,07662331 0,08687827 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,07662331 0,08683734 ! JNK cascade GO:0007254 91 47 0,000 0,07662331 0,08679646 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,07662331 0,08675562 ! methylation GO:0032259 90 47 0,000 0,07662331 0,08671481 ! protein homooligomerization GO:0051260 76 47 0,000 0,07662331 0,08667404 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,0781894 0,08840399 ! Notch signaling pathway GO:0007219 96 48 0,000 0,0781894 0,08836246 ! cellular component disassembly GO:0022411 86 48 0,000 0,0781894 0,08832098 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,0781894 0,08827953 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,0781894 0,08823813 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,0781894 0,08819676 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,0781894 0,08815543 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,0781894 0,08811414 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07975288 0,089834 ! regulation of action potential GO:0001508 95 49 0,000 0,07975288 0,08979196 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,07975288 0,08974996 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07975288 0,08970801 ! regulation of ion transport GO:0043269 77 49 0,000 0,07975288 0,08966609 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,07975288 0,08962421 ! peptide metabolic process GO:0006518 76 49 0,000 0,07975288 0,08958236 ! response to temperature stimulus GO:0009266 76 49 0,000 0,07975288 0,08954056 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07975288 0,0894988 ! endocrine system development GO:0035270 104 49 0,000 0,07975288 0,08945707 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,07975288 0,08941539 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,07975288 0,08937374 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07975288 0,08933213 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07975288 0,08929057 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,08131376 0,09099577 ! neuromuscular process GO:0050905 99 50 0,000 0,08131376 0,09095347 ! inner ear development GO:0048839 79 50 0,000 0,08131376 0,0909112 ! histone modification GO:0016570 91 50 0,000 0,08131376 0,09086898 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,08131376 0,09082679 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,08131376 0,09078464 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,08131376 0,09074254 ! positive regulation of binding GO:0051099 78 51 0,000 0,08287205 0,09243864 ! viral infectious cycle GO:0019058 99 51 0,000 0,08287205 0,0923958 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,08287205 0,09235301 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,08287205 0,09231025 ! excretion GO:0007588 83 51 0,000 0,08287205 0,09226754 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,08287205 0,09222486 ! chromatin remodeling GO:0006338 109 51 0,000 0,08287205 0,09218222 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,08287205 0,09213962 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,08287205 0,09209706 ! vesicle organization GO:0016050 107 51 0,000 0,08287205 0,09205454 ! regulation of cell shape GO:0008360 125 51 0,000 0,08287205 0,09201206 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,08287205 0,09196962 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,08442774 0,0936529 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,08442774 0,09360974 ! membrane fusion GO:0006944 110 52 0,000 0,08442774 0,09356663 ! covalent chromatin modification GO:0016569 101 52 0,000 0,08442774 0,09352355 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,08442774 0,09348051 ! amino acid activation GO:0043038 92 52 0,000 0,08442774 0,09343751 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,08442774 0,09339455 ! synapse organization GO:0050808 85 52 0,000 0,08442774 0,09335163 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,08598085 0,09502523 ! RNA catabolic process GO:0006401 93 53 0,000 0,08598085 0,0949816 ! regulation of translational initiation GO:0006446 82 53 0,000 0,08598085 0,09493801 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,08598085 0,09489446 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,08598085 0,09485095 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,08598085 0,09480748 ! cell maturation GO:0048469 100 53 0,000 0,08598085 0,09476405 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,08598085 0,09472066 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,08753137 0,09638466 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,08753137 0,09634057 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,08753137 0,09629652 ! cell recognition GO:0008037 85 54 0,000 0,08753137 0,09625251 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,08753137 0,09620854 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,08753137 0,09616461 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,08753137 0,09612071 ! glucose catabolic process GO:0006007 82 55 0,000 0,08907932 0,09777593 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,08907932 0,09773135 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08907932 0,0976868 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,08907932 0,0976423 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08907932 0,09759783 ! gastrulation GO:0007369 112 55 0,000 0,08907932 0,09755341 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,08907932 0,09750903 ! RNA elongation GO:0006354 79 55 0,000 0,08907932 0,09746469 ! regulation of actin filament length GO:0030832 105 56 0,000 0,09062469 0,09911046 ! sensory perception of smell GO:0007608 80 56 0,000 0,09062469 0,09906543 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,09062469 0,09902044 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,09062469 0,09897549 ! proton transport GO:0015992 94 56 0,000 0,09062469 0,09893058 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,09062469 0,09888572 ! muscle fiber development GO:0048747 112 57 0,000 0,09216749 0,10052357 ! lipid modification GO:0030258 97 57 0,000 0,09216749 0,10047802 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,09216749 0,10043251 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,09216749 0,10038705 ! maintenance of location GO:0051235 118 57 0,000 0,09216749 0,10034162 ! hydrogen transport GO:0006818 97 58 0,000 0,09370773 0,10197232 ! regulation of endocytosis GO:0030100 91 58 0,000 0,09370773 0,10192622 ! adult behavior GO:0030534 99 58 0,000 0,09370773 0,10188016 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,09370773 0,10183414 ! positive regulation of secretion GO:0051047 95 59 0,000 0,0952454 0,10345843 ! regulation of cellular component size GO:0032535 109 59 0,000 0,0952454 0,10341175 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,0952454 0,1033651 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,0952454 0,1033185 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,0952454 0,10327194 ! DNA catabolic process GO:0006308 86 59 0,000 0,0952454 0,10322542 ! establishment of organelle localization GO:0051656 109 59 0,000 0,0952454 0,10317894 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,09678051 0,10479474 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,09678051 0,1047476 ! regulation of heart contraction GO:0008016 110 60 0,000 0,09678051 0,1047005 ! camera-type eye development GO:0043010 116 60 0,000 0,09678051 0,10465345 ! kidney development GO:0001822 122 60 0,000 0,09678051 0,10460643 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,09831308 0,1062152 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,09831308 0,10616753 ! mesoderm development GO:0007498 119 61 0,000 0,09831308 0,1061199 ! tRNA processing GO:0008033 89 61 0,000 0,09831308 0,10607231 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,09831308 0,10602477 ! ear development GO:0043583 103 62 0,000 0,09984309 0,10762655 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09984309 0,10757836 ! gonad development GO:0008406 98 62 0,000 0,09984309 0,1075302 ! regulation of mitosis GO:0007088 105 63 0,000 0,10137055 0,10912642 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,10137055 0,10907762 ! detection of external stimulus GO:0009581 91 63 0,000 0,10137055 0,10902886 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,10137055 0,10898014 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,10137055 0,10893147 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,10289548 0,11052077 ! cell redox homeostasis GO:0045454 102 64 0,000 0,10289548 0,11047145 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,10289548 0,11042218 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,10289548 0,11037295 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,10289548 0,11032376 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,10441787 0,11190619 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,10441787 0,11185636 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,10441787 0,11180658 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,10441787 0,11175685 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,10441787 0,11170715 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,10593772 0,11328274 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,10593772 0,11323241 ! extracellular matrix organization GO:0030198 133 66 0,000 0,10593772 0,11318213 ! secondary metabolic process GO:0019748 116 66 0,000 0,10593772 0,1131319 ! developmental maturation GO:0021700 116 66 0,000 0,10593772 0,1130817 ! cell projection assembly GO:0030031 120 66 0,000 0,10593772 0,11303156 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,10745505 0,11459967 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,10745505 0,11454889 ! lung development GO:0030324 144 67 0,000 0,10745505 0,11449816 ! chromosome segregation GO:0007059 113 67 0,000 0,10745505 0,11444748 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,10745505 0,11439684 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,10745505 0,11434624 ! hexose catabolic process GO:0019320 104 67 0,000 0,10745505 0,11429569 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,10745505 0,11424518 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,10745505 0,11419472 ! adaptive immune response GO:0002250 119 67 0,000 0,10745505 0,1141443 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,10745505 0,11409393 ! amino acid transport GO:0006865 125 68 0,000 0,10896985 0,11565128 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,10896985 0,11560029 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,10896985 0,11554934 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,10896985 0,11549844 ! regulation of lipase activity GO:0060191 130 68 0,000 0,10896985 0,11544758 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,10896985 0,11539677 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,10896985 0,115346 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,11048213 0,11689534 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,11048213 0,11684396 ! urogenital system development GO:0001655 137 69 0,000 0,11048213 0,11679262 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,11048213 0,11674133 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,11048213 0,11669008 ! antigen processing and presentation GO:0019882 104 69 0,000 0,11048213 0,11663888 ! appendage morphogenesis GO:0035107 135 70 0,000 0,1119919 0,11818092 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,1119919 0,11812911 ! amine catabolic process GO:0009310 117 71 0,000 0,11349915 0,1196665 ! reproductive structure development GO:0048608 113 71 0,000 0,11349915 0,11961408 ! appendage development GO:0048736 136 71 0,000 0,11349915 0,11956171 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,11349915 0,11950939 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,11349915 0,11945711 ! regulation of immune effector process GO:0002697 137 71 0,000 0,11349915 0,11940488 ! acute inflammatory response GO:0002526 113 72 0,000 0,11500389 0,12093504 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,11500389 0,12088221 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,11500389 0,12082942 ! carbohydrate transport GO:0008643 110 72 0,000 0,11500389 0,12077668 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,11500389 0,12072398 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,11500389 0,12067133 ! respiratory system development GO:0060541 153 72 0,000 0,11500389 0,12061873 ! learning or memory GO:0007611 147 73 0,000 0,11650613 0,12214107 ! regulation of blood pressure GO:0008217 125 73 0,000 0,11650613 0,12208787 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,11650613 0,12203472 ! axon guidance GO:0007411 139 73 0,000 0,11650613 0,12198162 ! fertilization GO:0009566 90 73 0,000 0,11650613 0,12192856 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,11800587 0,12344441 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,11800587 0,12339076 ! neurotransmitter transport GO:0006836 123 74 0,000 0,11800587 0,12333716 ! meiosis GO:0007126 121 74 0,000 0,11800587 0,1232836 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,11800587 0,12323009 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,11800587 0,12317663 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,11800587 0,12312321 ! eye development GO:0001654 143 74 0,000 0,11800587 0,12306984 ! organelle localization GO:0051640 136 74 0,000 0,11800587 0,12301652 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,11950312 0,12452339 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,11950312 0,12446948 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,11950312 0,12441562 ! meiotic cell cycle GO:0051321 122 75 0,000 0,11950312 0,12436181 ! rhythmic process GO:0048511 128 75 0,000 0,11950312 0,12430804 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,12099787 0,1258085 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,12099787 0,12575416 ! defense response to bacterium GO:0042742 89 76 0,000 0,12099787 0,12569986 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,12099787 0,12564561 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,12099787 0,1255914 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,12249013 0,12708549 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,12249013 0,12703072 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,12249013 0,12697599 ! blood coagulation GO:0007596 146 78 0,000 0,12397991 0,12846498 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,12397991 0,12840967 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,12397991 0,12835442 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,12546721 0,12983833 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,12546721 0,12978251 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,12546721 0,12972674 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,12546721 0,12967101 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,12546721 0,12961534 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,12546721 0,12955971 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,12695204 0,13103673 ! response to metal ion GO:0010038 140 80 0,000 0,12695204 0,13098053 ! muscle cell differentiation GO:0042692 159 80 0,000 0,12695204 0,13092439 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,12695204 0,1308683 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,12843439 0,13233968 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,12843439 0,13228303 ! digestion GO:0007586 112 81 0,000 0,12843439 0,13222642 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,12843439 0,13216987 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,12843439 0,13211336 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,12991428 0,13357853 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,12991428 0,13352147 ! response to nutrient GO:0007584 125 82 0,000 0,12991428 0,13346446 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,12991428 0,13340749 ! response to oxygen levels GO:0070482 176 83 0,000 0,1313917 0,13486708 ! regulation of lyase activity GO:0051339 160 83 0,000 0,1313917 0,13480957 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,13286666 0,13626479 ! hemostasis GO:0007599 158 84 0,000 0,13286666 0,13620673 ! negative regulation of transport GO:0051051 153 84 0,000 0,13286666 0,13614872 ! regulation of ligase activity GO:0051340 142 84 0,000 0,13286666 0,13609076 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,13286666 0,13603285 ! response to unfolded protein GO:0006986 131 85 0,000 0,13433917 0,13748194 ! nucleosome assembly GO:0006334 122 85 0,000 0,13433917 0,13742349 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,13433917 0,13736508 ! amine biosynthetic process GO:0009309 138 86 0,000 0,13580923 0,13880926 ! response to inorganic substance GO:0010035 153 86 0,000 0,13580923 0,13875032 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,13580923 0,13869142 ! chromatin assembly GO:0031497 124 86 0,000 0,13580923 0,13863258 ! tube morphogenesis GO:0035239 176 86 0,000 0,13580923 0,13857379 ! alcohol catabolic process GO:0046164 130 86 0,000 0,13580923 0,13851505 ! amine transport GO:0015837 155 86 0,000 0,13580923 0,13845635 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,13727683 0,13989329 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,13727683 0,13983406 ! regulation of protein transport GO:0051223 154 87 0,000 0,13727683 0,13977489 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,138742 0,14120696 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,138742 0,14114725 ! regulation of DNA binding GO:0051101 155 88 0,000 0,138742 0,14108759 ! regulation of neurological system process GO:0031644 148 88 0,000 0,138742 0,14102799 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,138742 0,14096843 ! cellular defense response GO:0006968 114 89 0,000 0,14020472 0,1423945 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,14020472 0,14233441 ! ossification GO:0001503 188 90 0,000 0,14166501 0,14375623 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,14166501 0,14369562 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,14166501 0,14363507 ! sex differentiation GO:0007548 145 90 0,000 0,14166501 0,14357456 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,14166501 0,14351411 ! bone development GO:0060348 189 91 0,000 0,14312287 0,14492998 ! sterol metabolic process GO:0016125 152 91 0,000 0,14312287 0,144869 ! response to protein stimulus GO:0051789 149 91 0,000 0,14312287 0,14480808 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,14312287 0,14474721 ! nucleosome organization GO:0034728 138 92 0,000 0,1445783 0,14615773 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,1445783 0,14609634 ! vitamin metabolic process GO:0006766 139 92 0,000 0,1445783 0,14603501 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,1460313 0,14744075 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,1460313 0,14737891 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,1460313 0,14731711 ! regulation of membrane potential GO:0042391 164 93 0,000 0,1460313 0,14725537 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,1460313 0,14719368 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,14748189 0,14859356 ! female pregnancy GO:0007565 164 94 0,000 0,14748189 0,14853136 ! transcription initiation GO:0006352 153 94 0,000 0,14748189 0,14846922 ! regulation of T cell activation GO:0050863 158 94 0,000 0,14748189 0,14840712 ! forebrain development GO:0030900 188 95 0,000 0,14893006 0,14980173 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,15037582 0,15119274 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,15037582 0,15112958 ! positive regulation of immune response GO:0050778 156 96 0,000 0,15037582 0,15106648 ! detection of stimulus GO:0051606 151 96 0,000 0,15037582 0,15100343 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,15181917 0,15238921 ! protein ubiquitination GO:0016567 217 97 0,000 0,15181917 0,15232566 ! hormone metabolic process GO:0042445 157 97 0,000 0,15181917 0,15226216 ! regulation of protein localization GO:0032880 176 97 0,000 0,15181917 0,15219872 ! response to virus GO:0009615 160 98 0,000 0,15326012 0,15357928 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,15326012 0,15351534 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,15326012 0,15345145 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,15469866 0,15482737 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,15469866 0,15476299 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,15469866 0,15469866 GO:0060538|skeletal muscle organ development,