pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/673-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! phosphoinositide phosphorylation GO:0046854 33 18 3,000 5,909E-08 1,422E-04 ! lipid phosphorylation GO:0046834 35 19 3,000 7,473E-08 8,99E-05 ! embryonic cleavage GO:0040016 6 5 2,000 9,565E-08 7,671E-05 ! nuclear migration GO:0007097 12 6 2,000 1,91E-07 1,149E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,91E-07 9,191E-05 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 3,338E-07 1,338E-04 ! macrophage differentiation GO:0030225 11 7 2,000 3,338E-07 1,147E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 5,332E-07 1,604E-04 ! nucleus localization GO:0051647 19 11 2,000 1,564E-06 4,18E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,082E-06 5,009E-04 ! filopodium assembly GO:0046847 32 16 2,000 5,266E-06 1,152E-03 ! microspike assembly GO:0030035 36 17 2,000 6,385E-06 1,28E-03 ! lipid modification GO:0030258 97 57 3,000 7,161E-06 1,325E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,648E-05 2,831E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 2,000 1,648E-05 2,643E-03 GO:0010810|regulation of cell-substrate adhesion, ! platelet activation GO:0030168 37 23 2,000 1,648E-05 2,478E-03 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 1,82E-05 2,576E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 2,704E-05 3,615E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 3,368E-05 4,265E-03 ! regulation of ARF GTPase activity GO:0032312 65 32 2,000 4,551E-05 5,475E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 4,567E-05 5,233E-03 ! protein refolding GO:0042026 15 6 1,000 6,842E-05 7,482E-03 ! progesterone metabolic process GO:0042448 10 6 1,000 6,842E-05 7,157E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 7,074E-05 7,092E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 1,274E-04 0,01225639 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 1,274E-04 0,01178499 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,274E-04 0,01134851 ! regulation of ARF protein signal transduction GO:0032012 102 48 2,000 1,548E-04 0,01330381 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,635E-04 0,01356574 ! S phase GO:0051320 9 9 1,000 1,635E-04 0,01311355 GO:0000084|S phase of mitotic cell cycle, ! regulation of cell projection organization GO:0031344 121 50 2,000 1,749E-04 0,01357517 ! establishment of organelle localization GO:0051656 109 59 2,000 2,861E-04 0,02151237 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,985E-04 0,02176471 ! entry into host cell GO:0030260 32 12 1,000 2,985E-04 0,02112457 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of protein complex assembly GO:0043254 117 61 2,000 3,158E-04 0,02170761 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 3,474E-04 0,0232151 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 3,523E-04 0,02290924 ! myeloid cell differentiation GO:0030099 111 65 2,000 3,809E-04 0,02411711 ! cell projection assembly GO:0030031 120 66 2,000 3,984E-04 0,02457988 ! cAMP biosynthetic process GO:0006171 23 14 1,000 4,104E-04 0,02468846 ! activation of MAPK activity GO:0000187 115 67 2,000 4,165E-04 0,02443923 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 4,729E-04 0,02709241 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 1,000 4,729E-04 0,02646235 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 5,397E-04 0,02951421 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 5,397E-04 0,02885834 ! organelle localization GO:0051640 136 74 2,000 5,575E-04 0,02916052 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 5,799E-04 0,0296836 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,109E-04 0,03061932 ! blood coagulation GO:0007596 146 78 2,000 6,503E-04 0,03193005 GO:0050817|coagulation, ! hemostasis GO:0007599 158 84 2,000 8,07E-04 0,03883253 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 8,498E-04 0,04009288 ! cAMP metabolic process GO:0046058 36 20 1,000 8,498E-04 0,03932186 ! C21-steroid hormone metabolic process GO:0008207 33 20 1,000 8,498E-04 0,03857994 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 8,498E-04 0,0378655 ! regulation of vasoconstriction GO:0019229 39 21 1,000 9,38E-04 0,04103326 ! regulation of cell adhesion GO:0030155 212 89 2,000 9,545E-04 0,04100763 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 1,03E-03 0,04349227 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 1,03E-03 0,04274241 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,03E-03 0,04201796 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 1,03E-03 0,04131766 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 1,084E-03 0,04275403 ! leukocyte differentiation GO:0002521 202 96 2,000 1,188E-03 0,04610274 ! vesicle docking GO:0048278 47 24 1,000 1,228E-03 0,04688512 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,228E-03 0,04615254 ! vasculogenesis GO:0001570 46 25 1,000 1,333E-03 0,04932536 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,333E-03 0,04857801 ! interaction with host GO:0051701 62 25 1,000 1,333E-03 0,04785296 ! initiation of viral infection GO:0019059 57 26 1,000 1,442E-03 0,05100736 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,442E-03 0,05026812 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,442E-03 0,04955 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,442E-03 0,04885212 ! mitochondrial membrane organization GO:0007006 57 27 1,000 1,555E-03 0,05195521 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 1,555E-03 0,05124349 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 1,672E-03 0,05436391 ! membrane docking GO:0022406 61 30 1,000 1,919E-03 0,06155612 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 2,182E-03 0,06907236 ! mismatch repair GO:0006298 46 34 1,000 2,461E-03 0,07689564 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 2,461E-03 0,0759098 ! hormone biosynthetic process GO:0042446 57 36 1,000 2,756E-03 0,08393377 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 2,909E-03 0,08749929 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 2,909E-03 0,08641905 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 3,735E-03 0,10959631 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 4,277E-03 0,12398144 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 4,465E-03 0,12789644 ! response to insulin stimulus GO:0032868 95 46 1,000 4,465E-03 0,12639178 ! positive regulation of protein transport GO:0051222 72 46 1,000 4,465E-03 0,12492211 ! protein homooligomerization GO:0051260 76 47 1,000 4,657E-03 0,12879582 ! mitochondrial transport GO:0006839 82 48 1,000 4,853E-03 0,13268437 ! viral infectious cycle GO:0019058 99 51 1,000 5,463E-03 0,14767539 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 5,888E-03 0,15739521 ! regulation of intracellular transport GO:0032386 101 57 1,000 6,781E-03 0,17929622 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 7,49E-03 0,19586741 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 7,733E-03 0,20005255 ! viral reproductive process GO:0022415 126 62 1,000 7,979E-03 0,20423913 ! regulation of mitosis GO:0007088 105 63 1,000 8,23E-03 0,20842668 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 8,23E-03 0,20625557 ! cellular hormone metabolic process GO:0034754 113 67 1,000 9,265E-03 0,22982129 ! viral reproduction GO:0016032 134 68 1,000 9,533E-03 0,23404575 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01063748 0,25852301 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01074548 0,2585362 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01074548 0,25597644 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01074548 0,25346686 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01074548 0,25100602 ! neuron fate determination GO:0048664 7 5 0,000 0,01074548 0,2485925 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01074548 0,24622495 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01074548 0,24390208 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01074548 0,24162262 ! polyol transport GO:0015791 12 5 0,000 0,01074548 0,23938537 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01074548 0,23718918 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01074548 0,23503291 ! response to superoxide GO:0000303 10 5 0,000 0,01074548 0,2329155 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01074548 0,23083589 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01074548 0,2287931 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01074548 0,22678614 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01074548 0,22481409 ! female meiosis GO:0007143 7 5 0,000 0,01074548 0,22287604 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01074548 0,22097111 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01074548 0,21909848 ! cobalt ion transport GO:0006824 11 5 0,000 0,01074548 0,21725731 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01074548 0,21544683 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01074548 0,21366628 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01074548 0,21191492 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01074548 0,21019203 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01074548 0,20849694 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01074548 0,20682896 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01074548 0,20518746 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01074548 0,20357181 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01074548 0,20198141 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01074548 0,20041566 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01074548 0,198874 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01074548 0,19735588 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01074548 0,19586076 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01074548 0,19438812 ! negative chemotaxis GO:0050919 14 5 0,000 0,01074548 0,19293746 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01074548 0,1915083 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01074548 0,19010015 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01074548 0,18871256 ! behavioral response to pain GO:0048266 9 5 0,000 0,01074548 0,18734507 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01074548 0,18599727 ! Notch receptor processing GO:0007220 8 5 0,000 0,01074548 0,18466871 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01074548 0,18335901 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01074548 0,18206775 ! micturition GO:0060073 9 5 0,000 0,01074548 0,18079455 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01074548 0,17953903 ! copulation GO:0007620 9 5 0,000 0,01074548 0,17830083 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01074548 0,17707959 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01074548 0,17587497 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01074548 0,17468662 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01074548 0,17351423 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01074548 0,17235747 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01074548 0,17121603 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01074548 0,17008961 ! grooming behavior GO:0007625 6 5 0,000 0,01074548 0,16897791 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01074548 0,16788065 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01074548 0,16679755 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01074548 0,16572833 ! response to protozoan GO:0001562 10 5 0,000 0,01074548 0,16467274 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01074548 0,16363051 ! lymph vessel development GO:0001945 10 5 0,000 0,01074548 0,16260138 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01074548 0,16158513 ! endochondral ossification GO:0001958 16 5 0,000 0,01074548 0,16058149 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01074548 0,15959025 ! parathyroid gland development GO:0060017 13 5 0,000 0,01074548 0,15861117 ! anagen GO:0042640 6 5 0,000 0,01074548 0,15764402 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01074548 0,15668861 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01074548 0,1557447 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01074548 0,1548121 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01074548 0,1538906 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01074548 0,15298 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01074548 0,15208012 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01074548 0,15119076 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01074548 0,15031174 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01074548 0,14944289 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01074548 0,14858402 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01074548 0,14773497 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01074548 0,14689557 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01074548 0,14606565 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01074548 0,14524506 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01074548 0,14443363 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01074548 0,14363122 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01074548 0,14283768 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01074548 0,14205286 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01074548 0,14127661 ! histidine catabolic process GO:0006548 6 5 0,000 0,01074548 0,1405088 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01074548 0,1397493 ! microvillus organization GO:0032528 7 5 0,000 0,01074548 0,13899796 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01074548 0,13825465 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01074548 0,13751926 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01074548 0,13679164 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01074548 0,13607168 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01074548 0,13535927 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01074548 0,13465427 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01074548 0,13395658 ! polyol catabolic process GO:0046174 7 5 0,000 0,01074548 0,13326608 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01074548 0,13258267 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01074548 0,13190622 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01074548 0,13123665 ! muscle cell migration GO:0014812 8 5 0,000 0,01074548 0,13057384 ! mitochondrial fission GO:0000266 8 5 0,000 0,01074548 0,12991769 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01074548 0,1292681 ! mRNA transcription GO:0009299 9 5 0,000 0,01074548 0,12862498 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01074548 0,12798822 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01074548 0,12735773 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01074548 0,12673343 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01074548 0,12611522 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01074548 0,12550301 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01074548 0,12489672 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01074548 0,12429625 ! response to food GO:0032094 6 5 0,000 0,01074548 0,12370153 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01074548 0,12311248 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01074548 0,12252901 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01074548 0,12195104 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01074548 0,1213785 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01074548 0,12081131 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01074548 0,1202494 ! forebrain neuron development GO:0021884 13 5 0,000 0,01074548 0,11969269 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01074548 0,11914111 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01074548 0,11859459 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01074548 0,11805306 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01074548 0,11751645 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01074548 0,11698471 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01074548 0,11645775 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01074548 0,11593552 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01074548 0,11541795 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01074548 0,11490498 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01074548 0,11439655 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01074548 0,1138926 ! basic amino acid transport GO:0015802 11 5 0,000 0,01074548 0,11339307 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01074548 0,1128979 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01074548 0,11240704 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01074548 0,11192043 ! depyrimidination GO:0045008 10 5 0,000 0,01074548 0,11143802 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01074548 0,11095974 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01074548 0,11048556 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01074548 0,1100154 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01074548 0,10954924 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01074548 0,109087 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01074548 0,10862866 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01074548 0,10817414 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01074548 0,10772342 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01074548 0,10727643 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01074548 0,10683314 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01074548 0,1063935 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01074548 0,10595746 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01074548 0,10552498 ! response to arsenic GO:0046685 10 5 0,000 0,01074548 0,10509602 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01074548 0,10467053 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01074548 0,10424847 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01074548 0,1038298 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01074548 0,10341448 ! response to cadmium ion GO:0046686 7 5 0,000 0,01074548 0,10300247 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01074548 0,10259373 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01074548 0,10218822 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01074548 0,10178591 ! decidualization GO:0046697 11 5 0,000 0,01074548 0,10138675 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01074548 0,1009907 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01074548 0,10059774 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01074548 0,10020783 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01074548 0,09982093 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01074548 0,099437 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01074548 0,09905602 ! neural tube patterning GO:0021532 7 5 0,000 0,01074548 0,09867794 ! peroxisome fission GO:0016559 5 5 0,000 0,01074548 0,09830274 ! histone demethylation GO:0016577 10 5 0,000 0,01074548 0,09793038 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01074548 0,09756083 ! mitotic recombination GO:0006312 9 5 0,000 0,01074548 0,09719406 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01074548 0,09683004 ! metaphase plate congression GO:0051310 7 5 0,000 0,01074548 0,09646873 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01074548 0,09611011 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01074548 0,09575415 ! enteric nervous system development GO:0048484 8 5 0,000 0,01074548 0,09540081 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01074548 0,09505007 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01074548 0,09470191 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01074548 0,09435628 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01074548 0,09401316 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01074548 0,09367254 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01074548 0,09333437 ! plasminogen activation GO:0031639 5 5 0,000 0,01074548 0,09299863 ! B cell homeostasis GO:0001782 13 5 0,000 0,01074548 0,0926653 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01074548 0,09233436 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01074548 0,09200577 ! metaphase GO:0051323 8 5 0,000 0,01074548 0,0916795 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01074548 0,09135555 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01074548 0,09103387 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01074548 0,09071446 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01074548 0,09039727 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01074548 0,0900823 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01074548 0,08976951 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01074548 0,08945889 ! response to redox state GO:0051775 5 5 0,000 0,01074548 0,08915041 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01074548 0,08884406 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01074548 0,08853979 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01074548 0,08823761 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01074548 0,08793748 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01074548 0,08763939 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01074548 0,08734331 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01074548 0,08704923 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01074548 0,08675711 ! striatum development GO:0021756 9 5 0,000 0,01074548 0,08646696 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01074548 0,08617873 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01074548 0,08589243 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01074548 0,08560801 ! glial cell migration GO:0008347 11 5 0,000 0,01074548 0,08532548 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01074548 0,0850448 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01074548 0,08476597 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01074548 0,08448895 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01074548 0,08421375 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01074548 0,08394032 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01074548 0,08366867 ! neuroprotection GO:0043526 6 5 0,000 0,01074548 0,08339877 ! neural plate development GO:0001840 8 5 0,000 0,01074548 0,08313061 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01074548 0,08286417 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01074548 0,08259943 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01074548 0,08233637 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01074548 0,08207498 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01074548 0,08181525 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01074548 0,08155716 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01074548 0,08130069 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01074548 0,08104583 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01074548 0,08079256 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01074548 0,08054087 ! spindle assembly GO:0051225 6 5 0,000 0,01074548 0,08029075 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01074548 0,08004217 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01074548 0,07979512 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01074548 0,0795496 ! drug metabolic process GO:0017144 6 5 0,000 0,01074548 0,07930558 ! stem cell division GO:0017145 11 5 0,000 0,01074548 0,07906306 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01074548 0,07882201 ! organ regeneration GO:0031100 7 5 0,000 0,01074548 0,07858243 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01074548 0,0783443 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01074548 0,07810761 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01074548 0,07787235 ! exocytosis GO:0006887 133 74 1,000 0,01120994 0,08099434 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01120994 0,08075184 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,01179573 0,08471797 ! protein oligomerization GO:0051259 139 78 1,000 0,01239472 0,08875505 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01269913 0,09066501 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01288089 0,0916906 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01288089 0,09142013 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01288089 0,09115124 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01288089 0,09088394 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01288089 0,0906182 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01288089 0,090354 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01288089 0,09009135 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01288089 0,08983021 ! sleep GO:0030431 13 6 0,000 0,01288089 0,08957059 ! response to oxygen radical GO:0000305 11 6 0,000 0,01288089 0,08931246 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01288089 0,08905581 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01288089 0,08880064 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01288089 0,08854692 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01288089 0,08829465 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01288089 0,08804381 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01288089 0,0877944 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01288089 0,08754639 ! forebrain regionalization GO:0021871 8 6 0,000 0,01288089 0,08729978 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01288089 0,08705456 ! male meiosis GO:0007140 7 6 0,000 0,01288089 0,08681071 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01288089 0,08656822 ! response to zinc ion GO:0010043 9 6 0,000 0,01288089 0,08632708 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01288089 0,08608729 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01288089 0,08584882 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01288089 0,08561167 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01288089 0,08537582 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01288089 0,08514127 ! malate metabolic process GO:0006108 11 6 0,000 0,01288089 0,08490801 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01288089 0,08467602 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01288089 0,08444529 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01288089 0,08421582 ! opsonization GO:0008228 8 6 0,000 0,01288089 0,0839876 ! mating behavior GO:0007617 7 6 0,000 0,01288089 0,0837606 ! neuron remodeling GO:0016322 15 6 0,000 0,01288089 0,08353483 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01288089 0,08331028 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01288089 0,08308692 ! equilibrioception GO:0050957 14 6 0,000 0,01288089 0,08286477 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01288089 0,08264379 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01288089 0,082424 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01288089 0,08220537 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01288089 0,08198789 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01288089 0,08177156 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01288089 0,08155638 ! toxin metabolic process GO:0009404 11 6 0,000 0,01288089 0,08134232 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01288089 0,08112938 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01288089 0,08091755 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01288089 0,08070683 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01288089 0,0804972 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01288089 0,08028866 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01288089 0,0800812 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01288089 0,0798748 ! thymic T cell selection GO:0045061 12 6 0,000 0,01288089 0,07966947 ! protein lipoylation GO:0009249 10 6 0,000 0,01288089 0,07946519 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01288089 0,07926195 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01288089 0,07905975 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01288089 0,07885858 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01288089 0,07865843 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01288089 0,0784593 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01288089 0,07826117 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01288089 0,07806404 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01288089 0,0778679 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01288089 0,07767274 ! hyperosmotic response GO:0006972 9 6 0,000 0,01288089 0,07747856 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01288089 0,07728534 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01288089 0,07709309 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01288089 0,07690179 ! urea metabolic process GO:0019627 7 6 0,000 0,01288089 0,07671144 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01288089 0,07652203 ! neutrophil activation GO:0042119 8 6 0,000 0,01288089 0,07633355 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01288089 0,076146 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01288089 0,07595937 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01288089 0,07577365 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01288089 0,07558884 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01288089 0,07540492 ! neuron apoptosis GO:0051402 9 6 0,000 0,01288089 0,0752219 ! nucleoside salvage GO:0043174 9 6 0,000 0,01288089 0,07503976 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01288089 0,07485851 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01288089 0,07467813 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01288089 0,07449861 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01288089 0,07431996 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01288089 0,07414216 ! carnitine transport GO:0015879 10 6 0,000 0,01288089 0,07396521 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01288089 0,0737891 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01288089 0,07361383 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01288089 0,07343939 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01288089 0,07326577 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01288089 0,07309298 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01288089 0,07292099 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01288089 0,07274982 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01288089 0,07257944 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01288089 0,07240987 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01288089 0,07224108 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01288089 0,07207308 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01288089 0,07190585 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01288089 0,0717394 ! neural nucleus development GO:0048857 14 6 0,000 0,01288089 0,07157372 ! response to UV-C GO:0010225 11 6 0,000 0,01288089 0,07140881 ! astrocyte development GO:0014002 15 6 0,000 0,01288089 0,07124465 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01288089 0,07108124 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01288089 0,07091859 ! interaction with symbiont GO:0051702 13 6 0,000 0,01288089 0,07075667 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01288089 0,0705955 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01288089 0,07043505 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01288089 0,07027534 ! response to copper ion GO:0046688 10 6 0,000 0,01288089 0,07011634 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01288089 0,06995806 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01288089 0,0698005 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01288089 0,06964365 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01288089 0,0694875 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01288089 0,06933204 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01288089 0,06917728 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01288089 0,06902321 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01288089 0,06886983 ! hair follicle maturation GO:0048820 7 6 0,000 0,01288089 0,06871712 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01288089 0,06856509 ! Schwann cell development GO:0014044 15 6 0,000 0,01288089 0,06841374 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01288089 0,06826305 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01288089 0,06811302 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01288089 0,06796365 ! subpallium development GO:0021544 10 6 0,000 0,01288089 0,06781493 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01288089 0,06766686 ! histone ubiquitination GO:0016574 8 6 0,000 0,01288089 0,06751944 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01288089 0,06737266 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01288089 0,06722651 ! G2 phase GO:0051319 16 6 0,000 0,01288089 0,067081 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01288089 0,06693612 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01288089 0,06679186 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01288089 0,06664822 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01288089 0,0665052 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01288089 0,06636279 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01288089 0,06622099 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01288089 0,06607979 ! receptor internalization GO:0031623 10 6 0,000 0,01288089 0,0659392 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01288089 0,0657992 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01288089 0,06565979 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01288089 0,06552098 ! protein deubiquitination GO:0016579 14 6 0,000 0,01288089 0,06538275 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01288089 0,0652451 ! protein destabilization GO:0031648 9 6 0,000 0,01288089 0,06510803 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01288089 0,06497154 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01288089 0,06483561 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01288089 0,06470026 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01288089 0,06456546 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01288089 0,06443123 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01288089 0,06429756 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01288089 0,06416444 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01288089 0,06403187 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01288089 0,06389984 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01288089 0,06376836 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01288089 0,06363742 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01288089 0,06350701 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01288089 0,06337714 ! catecholamine transport GO:0051937 9 6 0,000 0,01288089 0,0632478 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01288089 0,06311899 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01288089 0,0629907 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01288089 0,06286293 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01288089 0,06273567 ! maternal placenta development GO:0001893 12 6 0,000 0,01288089 0,06260893 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01288089 0,06248271 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01288089 0,06235699 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01288089 0,06223177 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01288089 0,06210706 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01288089 0,06198285 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01288089 0,06185913 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01288089 0,0617359 ! protein import into nucleus GO:0006606 158 80 1,000 0,0130068 0,06221541 ! nuclear import GO:0051170 161 81 1,000 0,0133177 0,06357619 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01363184 0,06494694 ! response to unfolded protein GO:0006986 131 85 1,000 0,01459345 0,06939098 ! mitochondrion organization GO:0007005 148 86 1,000 0,01492034 0,07080538 ! tRNA transcription GO:0009304 14 7 0,000 0,01501176 0,07109903 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01501176 0,07095934 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01501176 0,07082021 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01501176 0,07068161 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01501176 0,07054356 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01501176 0,07040605 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01501176 0,07026908 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01501176 0,07013263 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01501176 0,06999672 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01501176 0,06986133 ! prostate gland development GO:0030850 13 7 0,000 0,01501176 0,06972646 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01501176 0,06959211 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01501176 0,06945828 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01501176 0,06932496 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01501176 0,06919216 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01501176 0,06905986 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01501176 0,06892806 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01501176 0,06879677 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01501176 0,06866598 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01501176 0,06853568 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01501176 0,06840588 ! glycolipid transport GO:0046836 10 7 0,000 0,01501176 0,06827657 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01501176 0,06814775 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01501176 0,06801941 ! neuron adhesion GO:0007158 12 7 0,000 0,01501176 0,06789155 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01501176 0,06776417 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01501176 0,06763728 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01501176 0,06751085 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01501176 0,0673849 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01501176 0,06725941 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01501176 0,0671344 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01501176 0,06700984 ! mRNA stabilization GO:0048255 18 7 0,000 0,01501176 0,06688575 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01501176 0,06676212 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01501176 0,06663894 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01501176 0,06651622 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01501176 0,06639394 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01501176 0,06627212 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01501176 0,06615074 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01501176 0,06602981 ! lipoprotein transport GO:0042953 14 7 0,000 0,01501176 0,06590932 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01501176 0,06578926 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01501176 0,06566965 ! rhythmic behavior GO:0007622 15 7 0,000 0,01501176 0,06555046 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01501176 0,06543171 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01501176 0,06531339 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01501176 0,0651955 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01501176 0,06507803 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01501176 0,06496098 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01501176 0,06484435 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01501176 0,06472815 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01501176 0,06461235 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01501176 0,06449697 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01501176 0,06438201 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01501176 0,06426745 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01501176 0,0641533 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01501176 0,06403955 ! spinal cord patterning GO:0021511 13 7 0,000 0,01501176 0,0639262 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01501176 0,06381326 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01501176 0,06370071 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01501176 0,06358857 ! adrenal gland development GO:0030325 17 7 0,000 0,01501176 0,06347681 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01501176 0,06336545 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01501176 0,06325448 ! ovulation GO:0030728 9 7 0,000 0,01501176 0,06314389 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01501176 0,06303369 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01501176 0,06292388 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01501176 0,06281444 ! microtubule nucleation GO:0007020 20 7 0,000 0,01501176 0,06270539 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01501176 0,06259672 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01501176 0,06248842 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01501176 0,06238049 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01501176 0,06227294 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01501176 0,06216576 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01501176 0,06205894 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01501176 0,0619525 ! galactose metabolic process GO:0006012 13 7 0,000 0,01501176 0,06184641 ! vesicle fusion GO:0006906 17 7 0,000 0,01501176 0,06174069 ! response to dietary excess GO:0002021 8 7 0,000 0,01501176 0,06163533 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01501176 0,06153033 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01501176 0,06142569 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01501176 0,0613214 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01501176 0,06121747 ! organ growth GO:0035265 15 7 0,000 0,01501176 0,06111388 ! purine salvage GO:0043101 10 7 0,000 0,01501176 0,06101065 ! nucleoside transport GO:0015858 8 7 0,000 0,01501176 0,06090777 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01501176 0,06080523 ! parturition GO:0007567 14 7 0,000 0,01501176 0,06070303 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01501176 0,06060118 ! rRNA modification GO:0000154 14 7 0,000 0,01501176 0,06049967 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01501176 0,0603985 ! spindle checkpoint GO:0031577 15 7 0,000 0,01501176 0,06029767 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01501176 0,06019718 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01501176 0,06009701 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01501176 0,05999718 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01501176 0,05989769 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01501176 0,05979852 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01501176 0,05969968 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01501176 0,05960116 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01501176 0,05950297 ! fibrinolysis GO:0042730 10 7 0,000 0,01501176 0,05940511 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01501176 0,05930756 ! eating behavior GO:0042755 7 7 0,000 0,01501176 0,05921034 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01501176 0,05911343 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01501176 0,05901684 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01501176 0,05892056 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01501176 0,0588246 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01501176 0,05872895 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01501176 0,05863361 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01501176 0,05853858 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01501176 0,05844386 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01501176 0,05834944 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01501176 0,05825533 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01501176 0,05816152 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01501176 0,05806801 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01501176 0,05797481 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01501176 0,0578819 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01501176 0,05778929 ! regulation of meiosis GO:0040020 12 7 0,000 0,01501176 0,05769697 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01501176 0,05760495 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01501176 0,05751322 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01501176 0,05742179 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01501176 0,05733064 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01501176 0,05723979 ! transcription termination GO:0006353 13 7 0,000 0,01501176 0,05714922 ! response to tumor cell GO:0002347 13 7 0,000 0,01501176 0,05705893 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01501176 0,05696894 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01501176 0,05687922 ! anaphase GO:0051322 17 7 0,000 0,01501176 0,05678979 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01501176 0,05670064 ! axonal fasciculation GO:0007413 18 7 0,000 0,01501176 0,05661176 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01501176 0,05652317 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01501176 0,05643485 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01501176 0,05634681 ! diuresis GO:0030146 12 7 0,000 0,01501176 0,05625904 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01501176 0,05617155 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01501176 0,05608432 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01501176 0,05599737 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01501176 0,05591069 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01501176 0,05582427 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01501176 0,05573813 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01501176 0,05565224 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01501176 0,05556662 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01501176 0,05548127 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01501176 0,05539617 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01501176 0,05531134 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01501176 0,05522677 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01501176 0,05514245 ! lymph node development GO:0048535 10 7 0,000 0,01501176 0,05505839 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01501176 0,05497459 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01501176 0,05489104 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01501176 0,05480775 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01501176 0,0547247 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01501176 0,05464191 ! adult feeding behavior GO:0008343 9 7 0,000 0,01501176 0,05455937 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01501176 0,05447708 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01501176 0,05439504 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01501176 0,05431324 ! muscle adaptation GO:0043500 14 7 0,000 0,01501176 0,05423169 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01501176 0,05415038 ! retina homeostasis GO:0001895 12 7 0,000 0,01501176 0,05406932 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01501176 0,0539885 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01501176 0,05390792 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01501176 0,05382758 ! protein prenylation GO:0018342 18 7 0,000 0,01501176 0,05374748 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01501176 0,05366762 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01501176 0,05358799 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01501176 0,0535086 ! protein localization in nucleus GO:0034504 176 87 1,000 0,01525038 0,05427871 ! regulation of protein transport GO:0051223 154 87 1,000 0,01525038 0,05419854 GO:0070201|regulation of establishment of protein localization, ! regulation of cell cycle process GO:0010564 149 90 1,000 0,01625927 0,05769881 ! response to protein stimulus GO:0051789 149 91 1,000 0,01660177 0,05882748 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01713811 0,06063866 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01713811 0,06054962 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,01713811 0,06046084 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01713811 0,06037231 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01713811 0,06028405 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01713811 0,06019604 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01713811 0,06010829 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01713811 0,0600208 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01713811 0,05993356 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01713811 0,05984658 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01713811 0,05975984 ! meiotic prophase I GO:0007128 13 8 0,000 0,01713811 0,05967336 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01713811 0,05958712 ! oligopeptide transport GO:0006857 15 8 0,000 0,01713811 0,05950114 ! UTP metabolic process GO:0046051 8 8 0,000 0,01713811 0,0594154 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01713811 0,05932991 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01713811 0,05924467 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01713811 0,05915967 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01713811 0,05907491 ! succinate metabolic process GO:0006105 14 8 0,000 0,01713811 0,0589904 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01713811 0,05890613 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01713811 0,0588221 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01713811 0,05873831 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01713811 0,05865475 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01713811 0,05857144 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01713811 0,05848836 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01713811 0,05840551 ! reflex GO:0060004 16 8 0,000 0,01713811 0,0583229 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01713811 0,05824052 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01713811 0,05815838 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01713811 0,05807647 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01713811 0,05799478 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01713811 0,05791333 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01713811 0,0578321 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01713811 0,05775111 ! pigment granule organization GO:0048753 16 8 0,000 0,01713811 0,05767034 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01713811 0,05758979 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01713811 0,05750947 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01713811 0,05742937 ! histidine metabolic process GO:0006547 16 8 0,000 0,01713811 0,0573495 GO:0009075|histidine family amino acid metabolic process, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01713811 0,05726985 ! glycine catabolic process GO:0006546 13 8 0,000 0,01713811 0,05719042 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01713811 0,05711121 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01713811 0,05703221 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01713811 0,05695344 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01713811 0,05687488 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01713811 0,05679654 ! melanin metabolic process GO:0006582 15 8 0,000 0,01713811 0,05671842 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01713811 0,05664051 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01713811 0,05656281 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01713811 0,05648533 ! macrophage activation GO:0042116 12 8 0,000 0,01713811 0,05640806 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01713811 0,056331 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01713811 0,05625415 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01713811 0,05617751 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01713811 0,05610108 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01713811 0,05602485 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01713811 0,05594883 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01713811 0,05587302 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01713811 0,05579742 ! osteoblast development GO:0002076 16 8 0,000 0,01713811 0,05572201 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01713811 0,05564682 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01713811 0,05557182 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01713811 0,05549703 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,01713811 0,05542243 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01713811 0,05534804 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01713811 0,05527385 ! response to UV-B GO:0010224 16 8 0,000 0,01713811 0,05519985 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01713811 0,05512606 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01713811 0,05505246 ! intermediate filament organization GO:0045109 12 8 0,000 0,01713811 0,05497905 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,01713811 0,05490585 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01713811 0,05483283 ! cellular extravasation GO:0045123 12 8 0,000 0,01713811 0,05476001 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01713811 0,05468739 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01713811 0,05461495 ! response to antibiotic GO:0046677 11 8 0,000 0,01713811 0,05454271 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01713811 0,05447066 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01713811 0,0543988 ! DNA topological change GO:0006265 12 8 0,000 0,01713811 0,05432713 ! response to tropane GO:0014073 15 8 0,000 0,01713811 0,05425565 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01713811 0,05418435 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01713811 0,05411324 ! melanosome transport GO:0032402 13 8 0,000 0,01713811 0,05404232 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01713811 0,05397158 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01713811 0,05390103 ! mast cell activation GO:0045576 14 8 0,000 0,01713811 0,05383067 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01713811 0,05376048 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01713811 0,05369048 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01713811 0,05362066 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01713811 0,05355103 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01713811 0,05348157 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01713811 0,05341229 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01713811 0,0533432 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01713811 0,05327428 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01713811 0,05320554 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01713811 0,05313697 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01713811 0,05306858 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01713811 0,05300037 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01713811 0,05293234 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01713811 0,05286447 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01713811 0,05279679 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01713811 0,05272927 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01713811 0,05266193 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01713811 0,05259476 ! hormone catabolic process GO:0042447 17 8 0,000 0,01713811 0,05252776 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01713811 0,05246093 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01713811 0,05239427 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01713811 0,05232778 ! ATP catabolic process GO:0006200 11 8 0,000 0,01713811 0,05226146 ! blastocyst growth GO:0001832 19 8 0,000 0,01713811 0,0521953 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01713811 0,05212932 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01713811 0,0520635 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01713811 0,05199784 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01713811 0,05193236 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01713811 0,05186703 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01713811 0,05180187 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01713811 0,05173688 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01713811 0,05167204 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01713811 0,05160737 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01713811 0,05154286 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01713811 0,05147851 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01713811 0,05141433 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01713811 0,0513503 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01713811 0,05128643 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01713811 0,05122272 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01713811 0,05115917 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01713811 0,05109577 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,017296 0,05150268 ! female pregnancy GO:0007565 164 94 1,000 0,01764769 0,05248498 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01800242 0,05347387 ! hormone metabolic process GO:0042445 157 97 1,000 0,01872094 0,05553955 ! regulation of protein localization GO:0032880 176 97 1,000 0,01872094 0,05547116 ! interphase GO:0051325 213 98 1,000 0,01908469 0,05647942 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01925993 0,05692801 ! axon extension GO:0048675 15 9 0,000 0,01925993 0,05685816 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01925993 0,05678848 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01925993 0,05671897 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01925993 0,05664963 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,01925993 0,05658046 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01925993 0,05651146 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01925993 0,05644263 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01925993 0,05637397 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01925993 0,05630547 ! phosphate transport GO:0006817 19 9 0,000 0,01925993 0,05623714 ! reproductive behavior GO:0019098 19 9 0,000 0,01925993 0,05616897 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01925993 0,05610097 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01925993 0,05603313 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01925993 0,05596546 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01925993 0,05589795 ! GTP metabolic process GO:0046039 9 9 0,000 0,01925993 0,0558306 ! RNA methylation GO:0001510 15 9 0,000 0,01925993 0,05576342 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01925993 0,0556964 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01925993 0,05562953 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01925993 0,05556283 ! artery development GO:0060840 24 9 0,000 0,01925993 0,05549629 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01925993 0,05542991 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01925993 0,05536368 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01925993 0,05529761 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01925993 0,05523171 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01925993 0,05516595 ! chemosensory behavior GO:0007635 20 9 0,000 0,01925993 0,05510036 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01925993 0,05503492 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01925993 0,05496963 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01925993 0,0549045 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01925993 0,05483953 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01925993 0,05477471 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01925993 0,05471004 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01925993 0,05464552 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01925993 0,05458116 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01925993 0,05451694 ! protein targeting to ER GO:0045047 22 9 0,000 0,01925993 0,05445288 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01925993 0,05438897 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01925993 0,05432521 ! T cell selection GO:0045058 23 9 0,000 0,01925993 0,05426159 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01925993 0,05419813 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01925993 0,05413481 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01925993 0,05407165 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01925993 0,05400863 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01925993 0,05394575 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01925993 0,05388302 ! mannose metabolic process GO:0006013 13 9 0,000 0,01925993 0,05382044 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01925993 0,05375801 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01925993 0,05369571 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01925993 0,05363357 ! receptor clustering GO:0043113 18 9 0,000 0,01925993 0,05357156 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01925993 0,0535097 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01925993 0,05344798 ! ruffle organization GO:0031529 15 9 0,000 0,01925993 0,05338641 ! retinol metabolic process GO:0042572 18 9 0,000 0,01925993 0,05332497 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01925993 0,05326368 ! behavioral fear response GO:0001662 22 9 0,000 0,01925993 0,05320253 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01925993 0,05314151 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01925993 0,05308064 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01925993 0,05301991 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01925993 0,05295932 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01925993 0,05289886 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01925993 0,05283854 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01925993 0,05277836 ! segment specification GO:0007379 13 9 0,000 0,01925993 0,05271832 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01925993 0,05265841 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01925993 0,05259864 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01925993 0,052539 ! response to amine stimulus GO:0014075 13 9 0,000 0,01925993 0,0524795 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01925993 0,05242014 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01925993 0,0523609 ! erythrocyte development GO:0048821 15 9 0,000 0,01925993 0,05230181 ! gas homeostasis GO:0033483 16 9 0,000 0,01925993 0,05224284 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01925993 0,05218401 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01925993 0,05212531 ! renal water homeostasis GO:0003091 14 9 0,000 0,01925993 0,05206674 ! postreplication repair GO:0006301 22 9 0,000 0,01925993 0,05200831 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01925993 0,05195 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01925993 0,05189183 ! icosanoid secretion GO:0032309 15 9 0,000 0,01925993 0,05183378 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01925993 0,05177587 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01925993 0,05171808 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01925993 0,05166042 ! regulation of cell division GO:0051302 15 9 0,000 0,01925993 0,0516029 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01925993 0,0515455 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01925993 0,05148822 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01925993 0,05143108 ! sterol catabolic process GO:0016127 11 9 0,000 0,01925993 0,05137406 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01925993 0,05131717 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01925993 0,0512604 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01925993 0,05120376 GO:0002820|negative regulation of adaptive immune response, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01925993 0,05114724 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,01925993 0,05109085 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01925993 0,05103458 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01925993 0,05097844 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01925993 0,05092242 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01925993 0,05086652 ! purine base metabolic process GO:0006144 21 9 0,000 0,01925993 0,05081075 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01925993 0,05075509 ! pigment granule transport GO:0051904 17 9 0,000 0,01925993 0,05069956 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01925993 0,05064415 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01925993 0,05058887 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01925993 0,0505337 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01925993 0,05047865 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01925993 0,05042372 ! mitochondrion localization GO:0051646 15 9 0,000 0,01925993 0,05036891 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,01945142 0,05081447 GO:0060538|skeletal muscle organ development, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02137725 0,05578488 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02137725 0,05572444 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02137725 0,05566413 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02137725 0,05560396 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02137725 0,05554391 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02137725 0,05548399 ! synapsis GO:0007129 13 10 0,000 0,02137725 0,0554242 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02137725 0,05536454 ! N-glycan processing GO:0006491 20 10 0,000 0,02137725 0,05530501 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02137725 0,05524561 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02137725 0,05518633 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02137725 0,05512718 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02137725 0,05506816 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02137725 0,05500926 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02137725 0,05495049 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02137725 0,05489185 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02137725 0,05483333 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02137725 0,05477493 ! androgen metabolic process GO:0008209 17 10 0,000 0,02137725 0,05471666 ! phospholipid efflux GO:0033700 16 10 0,000 0,02137725 0,05465851 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02137725 0,05460049 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02137725 0,05454259 ! lung alveolus development GO:0048286 26 10 0,000 0,02137725 0,05448481 ! pathogenesis GO:0009405 13 10 0,000 0,02137725 0,05442715 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02137725 0,05436962 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02137725 0,05431221 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02137725 0,05425491 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02137725 0,05419774 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02137725 0,05414069 ! endoderm development GO:0007492 16 10 0,000 0,02137725 0,05408376 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02137725 0,05402695 ! arginine catabolic process GO:0006527 13 10 0,000 0,02137725 0,05397026 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02137725 0,05391369 ! proline metabolic process GO:0006560 13 10 0,000 0,02137725 0,05385723 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02137725 0,0538009 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02137725 0,05374468 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02137725 0,05368858 ! V(D)J recombination GO:0033151 28 10 0,000 0,02137725 0,0536326 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02137725 0,05357673 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02137725 0,05352098 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02137725 0,05346534 ! B cell proliferation GO:0042100 18 10 0,000 0,02137725 0,05340982 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02137725 0,05335442 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02137725 0,05329913 ! multicellular organism growth GO:0035264 18 10 0,000 0,02137725 0,05324395 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02137725 0,05318889 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02137725 0,05313395 ! epithelial cell development GO:0002064 20 10 0,000 0,02137725 0,05307911 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02137725 0,05302439 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02137725 0,05296978 ! macroautophagy GO:0016236 17 10 0,000 0,02137725 0,05291529 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02137725 0,0528609 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02137725 0,05280663 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02137725 0,05275247 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02137725 0,05269842 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02137725 0,05264448 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02137725 0,05259065 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02137725 0,05253694 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02137725 0,05248333 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02137725 0,05242983 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02137725 0,05237644 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02137725 0,05232315 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02137725 0,05226998 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02137725 0,05221691 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02137725 0,05216395 ! response to dsRNA GO:0043331 20 10 0,000 0,02137725 0,0521111 ! DNA ligation GO:0006266 19 10 0,000 0,02137725 0,05205836 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02137725 0,05200572 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02137725 0,05195319 ! melanosome localization GO:0032400 16 10 0,000 0,02137725 0,05190077 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02137725 0,05184845 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02137725 0,05179623 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02137725 0,05174412 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02137725 0,05169212 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02137725 0,05164022 ! mRNA cleavage GO:0006379 17 10 0,000 0,02137725 0,05158842 ! protein sumoylation GO:0016925 15 10 0,000 0,02137725 0,05153673 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02137725 0,05148514 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02137725 0,05143366 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02137725 0,05138228 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02137725 0,051331 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02137725 0,05127982 ! salivary gland development GO:0007431 27 10 0,000 0,02137725 0,05122874 ! prophase GO:0051324 15 10 0,000 0,02137725 0,05117777 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02137725 0,0511269 ! apical protein localization GO:0045176 15 10 0,000 0,02137725 0,05107613 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02137725 0,05102546 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02137725 0,05097489 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02137725 0,05092442 ! midbrain development GO:0030901 13 10 0,000 0,02137725 0,05087404 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02137725 0,05082377 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02137725 0,0507736 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02137725 0,05072353 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02137725 0,05067356 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02137725 0,05062368 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02137725 0,0505739 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02137725 0,05052422 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02137725 0,05047464 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02137725 0,05042516 ! oocyte development GO:0048599 17 10 0,000 0,02137725 0,05037577 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02137725 0,05032648 ! blastocyst formation GO:0001825 17 10 0,000 0,02137725 0,05027728 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02137725 0,05022818 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02137725 0,05017918 ! activation of innate immune response GO:0002218 12 10 0,000 0,02137725 0,05013027 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02137725 0,05008146 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02137725 0,05003274 ! response to nicotine GO:0035094 20 10 0,000 0,02137725 0,04998412 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02137725 0,04993559 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02137725 0,04988716 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02137725 0,04983882 ! localization within membrane GO:0051668 20 10 0,000 0,02137725 0,04979057 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02349006 0,05465869 ! respiratory burst GO:0045730 17 11 0,000 0,02349006 0,05460588 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02349006 0,05455317 ! neuron fate specification GO:0048665 17 11 0,000 0,02349006 0,05450057 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02349006 0,05444806 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02349006 0,05439566 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02349006 0,05434335 ! thyroid gland development GO:0030878 26 11 0,000 0,02349006 0,05429115 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,02349006 0,05423905 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02349006 0,05418705 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02349006 0,05413514 ! response to pain GO:0048265 24 11 0,000 0,02349006 0,05408334 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02349006 0,05403163 ! T cell proliferation GO:0042098 26 11 0,000 0,02349006 0,05398003 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02349006 0,05392852 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02349006 0,05387711 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02349006 0,0538258 ! bone resorption GO:0045453 16 11 0,000 0,02349006 0,05377459 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02349006 0,05372347 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02349006 0,05367245 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02349006 0,05362153 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02349006 0,0535707 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02349006 0,05351997 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02349006 0,05346934 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02349006 0,0534188 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02349006 0,05336836 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02349006 0,05331801 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02349006 0,05326776 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02349006 0,0532176 ! lipid digestion GO:0044241 18 11 0,000 0,02349006 0,05316753 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02349006 0,05311756 ! UV protection GO:0009650 19 11 0,000 0,02349006 0,05306769 ! adult heart development GO:0007512 14 11 0,000 0,02349006 0,05301791 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02349006 0,05296822 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02349006 0,05291862 ! temperature homeostasis GO:0001659 17 11 0,000 0,02349006 0,05286912 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02349006 0,05281971 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02349006 0,05277039 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02349006 0,05272117 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02349006 0,05267203 ! regulation of organ growth GO:0046620 13 11 0,000 0,02349006 0,05262299 ! pigment granule localization GO:0051875 20 11 0,000 0,02349006 0,05257404 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02349006 0,05252518 ! vasoconstriction GO:0042310 18 11 0,000 0,02349006 0,05247641 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02349006 0,05242773 ! embryonic axis specification GO:0000578 18 11 0,000 0,02349006 0,05237914 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02349006 0,05233064 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02349006 0,05228223 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02349006 0,05223391 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02349006 0,05218568 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02349006 0,05213754 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02349006 0,05208948 ! zymogen activation GO:0031638 15 11 0,000 0,02349006 0,05204152 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02349006 0,05199364 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02349006 0,05194585 ! nucleosome positioning GO:0016584 15 11 0,000 0,02349006 0,05189815 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02349006 0,05185054 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02349006 0,05180301 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02349006 0,05175558 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02349006 0,05170822 ! acid secretion GO:0046717 18 11 0,000 0,02349006 0,05166096 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02349006 0,05161378 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02349006 0,05156669 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02349006 0,05151968 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02349006 0,05147276 ! oocyte differentiation GO:0009994 18 11 0,000 0,02349006 0,05142592 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02349006 0,05137917 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02349006 0,05133251 ! cholesterol efflux GO:0033344 19 11 0,000 0,02349006 0,05128592 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02349006 0,05123943 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02349006 0,05119302 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02349006 0,05114669 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02349006 0,05110044 ! embryonic gut development GO:0048566 15 11 0,000 0,02349006 0,05105428 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02349006 0,0510082 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02349006 0,05096221 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02349006 0,0509163 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02349006 0,05087047 ! defense response to fungus GO:0050832 13 11 0,000 0,02349006 0,05082472 ! developmental induction GO:0031128 19 11 0,000 0,02349006 0,05077906 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02349006 0,05073347 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02349006 0,05068797 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02349006 0,05064255 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02349006 0,05059721 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02349006 0,05055196 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02349006 0,05050678 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02349006 0,05046169 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02559838 0,05494176 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02559838 0,05489279 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02559838 0,05484391 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02559838 0,05479512 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02559838 0,05474641 ! virus-host interaction GO:0019048 29 12 0,000 0,02559838 0,05469779 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02559838 0,05464926 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02559838 0,05460081 ! cartilage condensation GO:0001502 20 12 0,000 0,02559838 0,05455245 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02559838 0,05450417 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02559838 0,05445598 ! protein complex disassembly GO:0043241 27 12 0,000 0,02559838 0,05440787 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02559838 0,05435985 ! hippocampus development GO:0021766 26 12 0,000 0,02559838 0,05431192 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02559838 0,05426406 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02559838 0,0542163 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02559838 0,05416861 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02559838 0,05412101 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02559838 0,0540735 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02559838 0,05402606 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02559838 0,05397871 ! drug transport GO:0015893 16 12 0,000 0,02559838 0,05393145 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02559838 0,05388426 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02559838 0,05383716 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02559838 0,05379014 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02559838 0,0537432 ! focal adhesion formation GO:0048041 35 12 0,000 0,02559838 0,05369635 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02559838 0,05364957 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02559838 0,05360288 ! forebrain cell migration GO:0021885 21 12 0,000 0,02559838 0,05355627 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02559838 0,05350974 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02559838 0,05346329 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02559838 0,05341692 ! fear response GO:0042596 26 12 0,000 0,02559838 0,05337063 ! monoamine transport GO:0015844 18 12 0,000 0,02559838 0,05332443 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02559838 0,0532783 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02559838 0,05323225 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02559838 0,05318628 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02559838 0,05314039 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02559838 0,05309458 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02559838 0,05304885 ! protein homotetramerization GO:0051289 21 12 0,000 0,02559838 0,05300319 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02559838 0,05295762 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02559838 0,05291212 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02559838 0,05286671 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02559838 0,05282137 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02559838 0,0527761 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02559838 0,05273092 ! cranial nerve development GO:0021545 20 12 0,000 0,02559838 0,05268581 ! fucose catabolic process GO:0019317 22 12 0,000 0,02559838 0,05264078 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02559838 0,05259583 ! histone acetylation GO:0016573 26 12 0,000 0,02559838 0,05255095 ! histone methylation GO:0016571 26 12 0,000 0,02559838 0,05250615 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02559838 0,05246142 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02559838 0,05241678 ! gland morphogenesis GO:0022612 29 12 0,000 0,02559838 0,0523722 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02559838 0,05232771 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02559838 0,05228329 ! T cell homeostasis GO:0043029 25 12 0,000 0,02559838 0,05223894 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02559838 0,05219467 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02559838 0,05215048 ! spleen development GO:0048536 22 12 0,000 0,02559838 0,05210636 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02559838 0,05206231 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02559838 0,05201834 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02559838 0,05197444 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02559838 0,05193062 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02559838 0,05188687 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02559838 0,05184319 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02559838 0,05179959 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02559838 0,05175606 ! response to cold GO:0009409 17 12 0,000 0,02559838 0,0517126 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02559838 0,05166922 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02559838 0,05162591 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02770222 0,05582207 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02770222 0,05577536 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02770222 0,05572872 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02770222 0,05568216 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02770222 0,05563569 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02770222 0,05558928 ! lipid localization GO:0010876 28 13 0,000 0,02770222 0,05554296 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02770222 0,05549671 ! organelle fusion GO:0048284 32 13 0,000 0,02770222 0,05545054 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02770222 0,05540445 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02770222 0,05535843 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02770222 0,05531249 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02770222 0,05526663 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02770222 0,05522084 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02770222 0,05517513 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02770222 0,05512949 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02770222 0,05508393 ! methionine metabolic process GO:0006555 27 13 0,000 0,02770222 0,05503844 ! plasma membrane organization GO:0007009 24 13 0,000 0,02770222 0,05499303 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02770222 0,05494769 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02770222 0,05490243 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02770222 0,05485724 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02770222 0,05481213 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02770222 0,05476709 ! response to X-ray GO:0010165 25 13 0,000 0,02770222 0,05472213 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02770222 0,05467724 ! exocrine system development GO:0035272 32 13 0,000 0,02770222 0,05463242 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02770222 0,05458767 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02770222 0,054543 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02770222 0,05449841 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02770222 0,05445388 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02770222 0,05440943 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02770222 0,05436505 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02770222 0,05432074 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02770222 0,05427651 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02770222 0,05423234 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02770222 0,05418825 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02770222 0,05414423 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02770222 0,05410029 ! ribosome assembly GO:0042255 17 13 0,000 0,02770222 0,05405641 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,02770222 0,0540126 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02770222 0,05396887 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02770222 0,0539252 ! chromatin silencing GO:0006342 26 13 0,000 0,02770222 0,05388161 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02770222 0,05383809 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02770222 0,05379463 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02770222 0,05375125 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02770222 0,05370794 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02770222 0,05366469 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02770222 0,05362152 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02770222 0,05357842 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02770222 0,05353538 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02770222 0,05349242 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02770222 0,05344952 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02770222 0,05340669 ! embryonic placenta development GO:0001892 23 13 0,000 0,02770222 0,05336393 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,02770222 0,05332124 ! insulin secretion GO:0030073 23 13 0,000 0,02770222 0,05327862 ! actin filament polymerization GO:0030041 24 13 0,000 0,02770222 0,05323606 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02770222 0,05319358 ! acrosome reaction GO:0007340 18 13 0,000 0,02770222 0,05315116 ! rRNA transcription GO:0009303 25 14 0,000 0,02980159 0,05713357 ! lactation GO:0007595 26 14 0,000 0,02980159 0,05708808 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02980159 0,05704266 ! reproductive cellular process GO:0048610 20 14 0,000 0,02980159 0,05699732 ! tRNA modification GO:0006400 20 14 0,000 0,02980159 0,05695205 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02980159 0,05690685 ! regulation of S phase GO:0033261 23 14 0,000 0,02980159 0,05686172 ! water transport GO:0006833 21 14 0,000 0,02980159 0,05681666 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02980159 0,05677168 ! non-recombinational repair GO:0000726 25 14 0,000 0,02980159 0,05672676 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02980159 0,05668192 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02980159 0,05663715 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02980159 0,05659245 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02980159 0,05654781 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02980159 0,05650325 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02980159 0,05645876 ! palate development GO:0060021 31 14 0,000 0,02980159 0,05641434 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02980159 0,05636999 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02980159 0,05632571 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02980159 0,0562815 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02980159 0,05623736 ! arginine metabolic process GO:0006525 17 14 0,000 0,02980159 0,05619328 ! regulation of heart rate GO:0002027 24 14 0,000 0,02980159 0,05614928 ! organic alcohol transport GO:0015850 29 14 0,000 0,02980159 0,05610534 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02980159 0,05606148 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02980159 0,05601768 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02980159 0,05597395 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02980159 0,05593029 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02980159 0,05588669 ! L-amino acid transport GO:0015807 30 14 0,000 0,02980159 0,05584317 ! bone mineralization GO:0030282 17 14 0,000 0,02980159 0,05579971 ! stem cell development GO:0048864 43 14 0,000 0,02980159 0,05575632 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02980159 0,055713 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02980159 0,05566974 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02980159 0,05562655 ! cerebellum development GO:0021549 21 14 0,000 0,02980159 0,05558343 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02980159 0,05554038 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02980159 0,05549739 ! response to gamma radiation GO:0010332 28 14 0,000 0,02980159 0,05545447 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02980159 0,05541161 ! cofactor transport GO:0051181 26 14 0,000 0,02980159 0,05536883 ! NADP metabolic process GO:0006739 24 14 0,000 0,02980159 0,0553261 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02980159 0,05528345 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02980159 0,05524085 ! intestinal absorption GO:0050892 25 14 0,000 0,02980159 0,05519833 ! oxygen transport GO:0015671 21 14 0,000 0,02980159 0,05515587 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02980159 0,05511347 ! male genitalia development GO:0030539 24 14 0,000 0,02980159 0,05507114 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02980159 0,05502888 ! regulation of axon extension GO:0030516 37 14 0,000 0,02980159 0,05498668 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02980159 0,05494454 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02980159 0,05490247 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0318965 0,05871688 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0318965 0,05867199 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0318965 0,05862717 ! superoxide anion generation GO:0042554 20 15 0,000 0,0318965 0,05858242 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0318965 0,05853773 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0318965 0,05849312 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0318965 0,05844857 ! copper ion transport GO:0006825 20 15 0,000 0,0318965 0,05840409 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0318965 0,05835967 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0318965 0,05831533 ! sulfate transport GO:0008272 23 15 0,000 0,0318965 0,05827105 ! response to cAMP GO:0051591 22 15 0,000 0,0318965 0,05822683 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0318965 0,05818269 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0318965 0,05813861 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0318965 0,0580946 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0318965 0,05805066 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0318965 0,05800678 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0318965 0,05796297 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0318965 0,05791922 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0318965 0,05787554 ! pituitary gland development GO:0021983 29 15 0,000 0,0318965 0,05783193 ! vesicle coating GO:0006901 33 15 0,000 0,0318965 0,05778838 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0318965 0,0577449 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0318965 0,05770148 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0318965 0,05765813 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0318965 0,05761484 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0318965 0,05757162 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0318965 0,05752846 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0318965 0,05748537 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0318965 0,05744234 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0318965 0,05739938 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0318965 0,05735648 ! histone deacetylation GO:0016575 20 15 0,000 0,0318965 0,05731364 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0318965 0,05727087 ! tissue regeneration GO:0042246 26 15 0,000 0,0318965 0,05722816 ! water homeostasis GO:0030104 27 15 0,000 0,0318965 0,05718552 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0318965 0,05714294 ! muscle maintenance GO:0046716 26 15 0,000 0,0318965 0,05710042 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0318965 0,05705797 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0318965 0,05701558 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0318965 0,05697325 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0318965 0,05693099 ! cell killing GO:0001906 29 15 0,000 0,0318965 0,05688878 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0318965 0,05684664 ! detection of bacterium GO:0016045 18 15 0,000 0,0318965 0,05680457 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0318965 0,05676255 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0318965 0,0567206 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0318965 0,05667871 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0318965 0,05663688 ! peptide hormone processing GO:0016486 23 15 0,000 0,0318965 0,05659511 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03398695 0,06025983 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03398695 0,06021546 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03398695 0,06017115 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03398695 0,06012691 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03398695 0,06008273 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03398695 0,06003861 ! bone remodeling GO:0046849 27 16 0,000 0,03398695 0,05999456 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03398695 0,05995058 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03398695 0,05990666 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03398695 0,0598628 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03398695 0,05981901 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03398695 0,05977529 ! startle response GO:0001964 28 16 0,000 0,03398695 0,05973162 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03398695 0,05968802 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03398695 0,05964449 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03398695 0,05960101 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03398695 0,0595576 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03398695 0,05951426 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03398695 0,05947098 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03398695 0,05942776 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03398695 0,0593846 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03398695 0,0593415 ! response to osmotic stress GO:0006970 25 16 0,000 0,03398695 0,05929847 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03398695 0,0592555 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03398695 0,05921259 ! fructose metabolic process GO:0006000 25 16 0,000 0,03398695 0,05916975 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03398695 0,05912696 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03398695 0,05908424 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03398695 0,05904158 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03398695 0,05899898 ! axon cargo transport GO:0008088 43 16 0,000 0,03398695 0,05895645 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03398695 0,05891397 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03398695 0,05887156 ! DNA replication initiation GO:0006270 27 16 0,000 0,03398695 0,0588292 ! neuron recognition GO:0008038 35 16 0,000 0,03398695 0,05878691 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03398695 0,05874468 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03398695 0,05870251 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03398695 0,0586604 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03398695 0,05861834 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03398695 0,05857635 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03398695 0,05853442 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03398695 0,05849255 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03398695 0,05845074 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03398695 0,05840899 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03398695 0,0583673 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03398695 0,05832567 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03398695 0,0582841 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03398695 0,05824259 ! defense response to virus GO:0051607 37 16 0,000 0,03398695 0,05820113 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03607295 0,06172939 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,03607295 0,06168552 ! metencephalon development GO:0022037 30 17 0,000 0,03607295 0,0616417 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03607295 0,06159796 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03607295 0,06155427 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03607295 0,06151064 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03607295 0,06146708 ! signal complex assembly GO:0007172 41 17 0,000 0,03607295 0,06142358 ! endothelial cell migration GO:0043542 28 17 0,000 0,03607295 0,06138014 ! inositol metabolic process GO:0006020 28 17 0,000 0,03607295 0,06133676 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03607295 0,06129345 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03607295 0,06125019 ! glial cell development GO:0021782 27 17 0,000 0,03607295 0,061207 ! limbic system development GO:0021761 36 17 0,000 0,03607295 0,06116386 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,03607295 0,06112079 ! adult walking behavior GO:0007628 33 17 0,000 0,03607295 0,06107778 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03607295 0,06103482 ! heart looping GO:0001947 30 17 0,000 0,03607295 0,06099193 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03607295 0,0609491 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03607295 0,06090633 ! myoblast differentiation GO:0045445 45 17 0,000 0,03607295 0,06086362 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03607295 0,06082097 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03607295 0,06077838 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03607295 0,06073584 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03607295 0,06069337 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03607295 0,06065096 ! glycine metabolic process GO:0006544 28 17 0,000 0,03607295 0,0606086 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03607295 0,06056631 ! NAD metabolic process GO:0019674 29 17 0,000 0,03607295 0,06052407 ! membrane budding GO:0006900 37 17 0,000 0,03607295 0,0604819 ! DNA integration GO:0015074 29 17 0,000 0,03607295 0,06043978 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03607295 0,06039772 ! regulation of protein binding GO:0043393 33 17 0,000 0,03607295 0,06035572 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03607295 0,06031377 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03607295 0,06027189 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03607295 0,06023006 ! genitalia development GO:0048806 30 17 0,000 0,03607295 0,06018829 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03607295 0,06014658 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03607295 0,06010493 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03607295 0,06006334 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03607295 0,0600218 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03607295 0,05998032 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03607295 0,0599389 ! steroid catabolic process GO:0006706 31 17 0,000 0,03607295 0,05989753 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03607295 0,05985622 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03607295 0,05981497 ! gas transport GO:0015669 25 17 0,000 0,03607295 0,05977377 ! organic cation transport GO:0015695 31 17 0,000 0,03607295 0,05973264 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03607295 0,05969155 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03607295 0,05965053 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03607295 0,05960956 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03607295 0,05956865 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03607295 0,05952779 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03815452 0,06291966 ! neuron maturation GO:0042551 42 18 0,000 0,03815452 0,06287656 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03815452 0,06283352 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03815452 0,06279055 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03815452 0,06274763 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03815452 0,06270477 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03815452 0,06266196 ! memory GO:0007613 31 18 0,000 0,03815452 0,06261922 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03815452 0,06257654 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03815452 0,06253391 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03815452 0,06249134 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03815452 0,06244883 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03815452 0,06240637 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03815452 0,06236398 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03815452 0,06232164 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03815452 0,06227936 ! response to retinoic acid GO:0032526 26 18 0,000 0,03815452 0,06223714 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03815452 0,06219497 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03815452 0,06215286 ! response to fungus GO:0009620 21 18 0,000 0,03815452 0,06211081 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03815452 0,06206882 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,03815452 0,06202688 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03815452 0,06198499 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03815452 0,06194317 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03815452 0,0619014 ! vitamin transport GO:0051180 27 18 0,000 0,03815452 0,06185969 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03815452 0,06181803 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03815452 0,06177643 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03815452 0,06173489 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03815452 0,0616934 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03815452 0,06165197 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03815452 0,06161059 ! nerve development GO:0021675 28 18 0,000 0,03815452 0,06156927 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03815452 0,061528 ! protein secretion GO:0009306 39 19 0,000 0,04023166 0,06483415 ! positive regulation of translation GO:0045727 30 19 0,000 0,04023166 0,06479075 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04023166 0,06474742 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04023166 0,06470413 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04023166 0,06466091 ! skin development GO:0043588 36 19 0,000 0,04023166 0,06461775 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04023166 0,06457464 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04023166 0,06453159 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04023166 0,0644886 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04023166 0,06444566 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04023166 0,06440279 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04023166 0,06435996 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04023166 0,0643172 ! cerebral cortex development GO:0021987 36 19 0,000 0,04023166 0,06427449 ! pigmentation during development GO:0048066 41 19 0,000 0,04023166 0,06423184 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04023166 0,06418925 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04023166 0,06414671 ! heme metabolic process GO:0042168 36 19 0,000 0,04023166 0,06410423 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04023166 0,0640618 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04023166 0,06401944 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04023166 0,06397712 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04023166 0,06393487 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04023166 0,06389266 ! peptide cross-linking GO:0018149 37 19 0,000 0,04023166 0,06385052 ! protein export from nucleus GO:0006611 36 19 0,000 0,04023166 0,06380843 ! heart process GO:0003015 30 19 0,000 0,04023166 0,06376639 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04023166 0,06372441 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04023166 0,06368249 ! visual learning GO:0008542 36 19 0,000 0,04023166 0,06364062 ! cellular pigmentation GO:0033059 36 19 0,000 0,04023166 0,06359881 ! G1 phase GO:0051318 40 19 0,000 0,04023166 0,06355705 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04023166 0,06351535 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04023166 0,0634737 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04023166 0,0634321 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04023166 0,06339056 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04023166 0,06334907 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04023166 0,06330764 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04023166 0,06326627 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04023166 0,06322494 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04023166 0,06318367 ! cilium assembly GO:0042384 37 19 0,000 0,04023166 0,06314246 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04023166 0,06310129 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04230439 0,06630903 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04230439 0,06626586 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04230439 0,06622275 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04230439 0,06617969 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04230439 0,06613669 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,04230439 0,06609375 ! response to vitamin GO:0033273 31 20 0,000 0,04230439 0,06605085 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04230439 0,06600802 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04230439 0,06596524 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04230439 0,06592252 ! response to alkaloid GO:0043279 38 20 0,000 0,04230439 0,06587985 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04230439 0,06583724 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04230439 0,06579468 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04230439 0,06575218 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04230439 0,06570973 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04230439 0,06566733 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04230439 0,065625 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,04230439 0,06558271 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04230439 0,06554048 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04230439 0,06549831 ! body fluid secretion GO:0007589 31 20 0,000 0,04230439 0,06545618 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04230439 0,06541412 ! peptide secretion GO:0002790 35 20 0,000 0,04230439 0,0653721 ! stem cell differentiation GO:0048863 53 20 0,000 0,04230439 0,06533015 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04230439 0,06528824 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04230439 0,06524639 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04230439 0,06520459 ! sensory perception of pain GO:0019233 30 20 0,000 0,04230439 0,06516285 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04230439 0,06512116 ! diencephalon development GO:0021536 34 20 0,000 0,04230439 0,06507952 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04230439 0,06503793 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04230439 0,0649964 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04230439 0,06495492 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04230439 0,0649135 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04230439 0,06487213 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04230439 0,06483081 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04230439 0,06478954 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04230439 0,06474833 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04230439 0,06470716 ! regulation of glucose import GO:0046324 29 20 0,000 0,04230439 0,06466605 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04230439 0,064625 ! actin filament-based movement GO:0030048 43 20 0,000 0,04230439 0,06458399 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04230439 0,06454304 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04230439 0,06450213 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04230439 0,06446128 ! negative regulation of translation GO:0017148 29 20 0,000 0,04230439 0,06442049 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04230439 0,06437974 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04230439 0,06433904 ! regulation of cell killing GO:0031341 42 21 0,000 0,04437271 0,06744204 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04437271 0,06739946 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04437271 0,06735694 ! hormone secretion GO:0046879 38 21 0,000 0,04437271 0,06731447 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04437271 0,06727205 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04437271 0,06722969 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04437271 0,06718738 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04437271 0,06714512 ! axis specification GO:0009798 38 21 0,000 0,04437271 0,06710292 ! ovarian follicle development GO:0001541 35 21 0,000 0,04437271 0,06706077 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,04437271 0,06701867 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04437271 0,06697663 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,04437271 0,06693464 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04437271 0,0668927 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04437271 0,06685081 ! cell aging GO:0007569 44 21 0,000 0,04437271 0,06680898 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04437271 0,06676719 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04437271 0,06672547 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04437271 0,06668379 ! cytolysis GO:0019835 24 21 0,000 0,04437271 0,06664216 ! vasodilation GO:0042311 39 21 0,000 0,04437271 0,06660059 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04437271 0,06655907 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04437271 0,0665176 ! oogenesis GO:0048477 36 21 0,000 0,04437271 0,06647618 ! DNA modification GO:0006304 34 21 0,000 0,04437271 0,06643481 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04437271 0,0663935 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04437271 0,06635223 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04437271 0,06631102 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04437271 0,06626986 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04437271 0,06622875 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04437271 0,06618769 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04437271 0,06614668 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04437271 0,06610572 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04437271 0,06606482 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04437271 0,06602396 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04437271 0,06598315 ! collagen catabolic process GO:0030574 28 21 0,000 0,04437271 0,0659424 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04437271 0,06590169 ! gut development GO:0048565 39 21 0,000 0,04437271 0,06586104 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04643663 0,06888196 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04643663 0,06883952 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04643663 0,06879713 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04643663 0,06875479 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04643663 0,06871251 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04643663 0,06867028 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04643663 0,0686281 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04643663 0,06858597 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04643663 0,06854389 ! regeneration GO:0031099 41 22 0,000 0,04643663 0,06850186 ! keratinization GO:0031424 28 22 0,000 0,04643663 0,06845989 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04643663 0,06841797 ! sensory perception of taste GO:0050909 28 22 0,000 0,04643663 0,06837609 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,04643663 0,06833427 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04643663 0,06829251 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04643663 0,06825079 ! vacuolar transport GO:0007034 36 22 0,000 0,04643663 0,06820912 ! lysosome organization GO:0007040 41 22 0,000 0,04643663 0,0681675 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04643663 0,06812594 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04643663 0,06808442 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,04643663 0,06804296 ! fucose metabolic process GO:0006004 39 22 0,000 0,04643663 0,06800155 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04643663 0,06796018 ! ureteric bud development GO:0001657 43 22 0,000 0,04643663 0,06791887 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04643663 0,06787761 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04643663 0,06783639 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04643663 0,06779523 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04643663 0,06775412 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04643663 0,06771305 ! sarcomere organization GO:0045214 30 22 0,000 0,04643663 0,06767204 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04643663 0,06763108 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04643663 0,06759016 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04643663 0,0675493 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04643663 0,06750848 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,04643663 0,06746772 ! protein stabilization GO:0050821 39 22 0,000 0,04643663 0,067427 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04849617 0,07037501 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04849617 0,07033259 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04849617 0,07029022 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04849617 0,07024791 ! gluconeogenesis GO:0006094 33 23 0,000 0,04849617 0,07020564 ! viral genome replication GO:0019079 41 23 0,000 0,04849617 0,07016342 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04849617 0,07012126 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04849617 0,07007914 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04849617 0,07003708 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04849617 0,06999506 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04849617 0,0699531 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04849617 0,06991119 ! visual behavior GO:0007632 42 23 0,000 0,04849617 0,06986933 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04849617 0,06982751 ! response to ethanol GO:0045471 46 23 0,000 0,04849617 0,06978575 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04849617 0,06974404 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04849617 0,06970237 ! peroxisome organization GO:0007031 37 23 0,000 0,04849617 0,06966076 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04849617 0,0696192 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04849617 0,06957768 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04849617 0,06953622 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04849617 0,0694948 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,04849617 0,06945344 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04849617 0,06941212 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04849617 0,06937085 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04849617 0,06932963 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04849617 0,06928846 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04849617 0,06924734 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04849617 0,06920627 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04849617 0,06916525 ! fatty acid transport GO:0015908 44 23 0,000 0,04849617 0,06912427 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04849617 0,06908335 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04849617 0,06904247 ! hormone transport GO:0009914 40 23 0,000 0,04849617 0,06900164 ! cell-cell recognition GO:0009988 25 23 0,000 0,04849617 0,06896086 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04849617 0,06892013 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04849617 0,06887944 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04849617 0,0688388 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04849617 0,06879822 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04849617 0,06875767 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05055132 0,07162925 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,05055132 0,07158709 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05055132 0,07154498 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05055132 0,07150292 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05055132 0,07146091 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05055132 0,07141895 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05055132 0,07137704 ! spinal cord development GO:0021510 47 24 0,000 0,05055132 0,07133517 ! vacuole organization GO:0007033 43 24 0,000 0,05055132 0,07129336 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05055132 0,07125159 ! digestive system process GO:0022600 39 24 0,000 0,05055132 0,07120988 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05055132 0,07116821 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05055132 0,07112659 ! regulation of behavior GO:0050795 43 24 0,000 0,05055132 0,07108502 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05055132 0,0710435 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05055132 0,07100203 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05055132 0,0709606 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,05055132 0,07091922 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05055132 0,0708779 ! membrane depolarization GO:0051899 39 24 0,000 0,05055132 0,07083662 ! pallium development GO:0021543 49 24 0,000 0,05055132 0,07079538 ! pentose metabolic process GO:0019321 35 24 0,000 0,05055132 0,0707542 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05055132 0,07071306 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05055132 0,07067198 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05055132 0,07063093 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05055132 0,07058994 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05055132 0,070549 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05055132 0,0705081 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05055132 0,07046725 ! regulation of amine transport GO:0051952 40 24 0,000 0,05055132 0,07042644 ! protein tetramerization GO:0051262 52 24 0,000 0,05055132 0,07038569 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0526021 0,07319876 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,0526021 0,07315644 ! myelination GO:0042552 45 25 0,000 0,0526021 0,07311418 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0526021 0,07307197 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0526021 0,0730298 ! phototransduction GO:0007602 33 25 0,000 0,0526021 0,07298769 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0526021 0,07294562 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,0526021 0,0729036 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,0526021 0,07286163 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,0526021 0,07281971 ! receptor metabolic process GO:0043112 46 25 0,000 0,0526021 0,07277783 ! chromosome condensation GO:0030261 45 25 0,000 0,0526021 0,07273601 ! response to starvation GO:0042594 42 25 0,000 0,0526021 0,07269423 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0526021 0,0726525 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,0526021 0,07261081 ! neural crest cell development GO:0014032 54 25 0,000 0,0526021 0,07256918 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0526021 0,07252759 ! negative regulation of cell development GO:0010721 73 25 0,000 0,0526021 0,07248605 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0526021 0,07244456 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0526021 0,07240312 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0526021 0,07236172 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0526021 0,07232037 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0526021 0,07227907 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,0526021 0,07223781 ! immunoglobulin production GO:0002377 55 25 0,000 0,0526021 0,07219661 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0526021 0,07215544 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0526021 0,07211433 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,0526021 0,07207326 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,0526021 0,07203224 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0526021 0,07199127 ! telomere organization GO:0032200 43 25 0,000 0,0526021 0,07195034 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0526021 0,07190946 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0526021 0,07186863 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05464852 0,07462221 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05464852 0,07457988 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05464852 0,0745376 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05464852 0,07449537 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05464852 0,07445319 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05464852 0,07441106 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05464852 0,07436897 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05464852 0,07432693 ! molting cycle process GO:0022404 50 26 0,000 0,05464852 0,07428494 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05464852 0,07424299 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,05464852 0,07420109 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05464852 0,07415924 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05464852 0,07411744 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,05464852 0,07407568 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05464852 0,07403397 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,05464852 0,07399231 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05464852 0,07395069 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05464852 0,07390913 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05464852 0,0738676 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05464852 0,07382613 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05464852 0,0737847 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05464852 0,07374332 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05464852 0,07370198 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05464852 0,07366069 ! blastocyst development GO:0001824 49 26 0,000 0,05464852 0,07361945 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05464852 0,07357825 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05464852 0,0735371 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05464852 0,073496 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,05669059 0,07619975 ! neuron fate commitment GO:0048663 48 27 0,000 0,05669059 0,0761572 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05669059 0,0761147 ! iron ion transport GO:0006826 59 27 0,000 0,05669059 0,07607225 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,05669059 0,07602985 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05669059 0,07598749 ! protein amino acid acylation GO:0043543 55 27 0,000 0,05669059 0,07594518 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05669059 0,07590292 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05669059 0,07586071 ! fat cell differentiation GO:0045444 50 27 0,000 0,05669059 0,07581854 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05669059 0,07577642 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05669059 0,07573434 ! autophagy GO:0006914 41 27 0,000 0,05669059 0,07569231 ! male gonad development GO:0008584 44 27 0,000 0,05669059 0,07565033 ! response to toxin GO:0009636 47 27 0,000 0,05669059 0,0756084 ! primary neural tube formation GO:0014020 51 27 0,000 0,05669059 0,07556651 ! base-excision repair GO:0006284 41 27 0,000 0,05669059 0,07552467 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05669059 0,07548287 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05669059 0,07544112 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05669059 0,07539942 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05669059 0,07535776 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,05669059 0,07531615 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05669059 0,07527459 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05669059 0,07523307 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05872831 0,07789433 ! circadian rhythm GO:0007623 50 28 0,000 0,05872831 0,07785141 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05872831 0,07780854 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05872831 0,07776572 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05872831 0,07772294 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05872831 0,07768022 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05872831 0,07763753 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05872831 0,0775949 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05872831 0,07755231 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05872831 0,07750977 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05872831 0,07746728 ! synaptogenesis GO:0007416 42 28 0,000 0,05872831 0,07742483 ! lipid oxidation GO:0034440 43 28 0,000 0,05872831 0,07738243 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05872831 0,07734007 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05872831 0,07729776 ! translational initiation GO:0006413 65 29 0,000 0,0607617 0,07993037 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0607617 0,07988669 ! regulation of pH GO:0006885 43 29 0,000 0,0607617 0,07984306 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0607617 0,07979948 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0607617 0,07975595 ! catechol metabolic process GO:0009712 54 29 0,000 0,0607617 0,07971246 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0607617 0,07966902 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0607617 0,07962563 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0607617 0,07958228 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0607617 0,07953898 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0607617 0,07949573 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0607617 0,07945253 ! cell fate determination GO:0001709 60 29 0,000 0,0607617 0,07940937 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0607617 0,07936626 ! detection of light stimulus GO:0009583 38 29 0,000 0,0607617 0,07932319 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,0607617 0,07928018 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,0607617 0,07923721 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,0607617 0,07919428 ! tissue homeostasis GO:0001894 48 29 0,000 0,0607617 0,07915141 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,0607617 0,07910858 ! phenol metabolic process GO:0018958 55 30 0,000 0,06279076 0,0817061 ! zinc ion transport GO:0006829 45 30 0,000 0,06279076 0,08166193 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06279076 0,08161782 ! cell junction assembly GO:0034329 78 30 0,000 0,06279076 0,08157375 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06279076 0,08152972 ! acute-phase response GO:0006953 49 30 0,000 0,06279076 0,08148575 ! myofibril assembly GO:0030239 47 30 0,000 0,06279076 0,08144182 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,06279076 0,08139794 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06279076 0,08135411 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06279076 0,08131032 ! phospholipid transport GO:0015914 51 30 0,000 0,06279076 0,08126658 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06279076 0,08122289 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06279076 0,08117925 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06279076 0,08113565 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06279076 0,0810921 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06279076 0,08104859 ! eye morphogenesis GO:0048592 60 30 0,000 0,06279076 0,08100514 ! regulation of B cell activation GO:0050864 50 30 0,000 0,06279076 0,08096172 ! response to heat GO:0009408 50 30 0,000 0,06279076 0,08091836 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06481551 0,08348293 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06481551 0,08343827 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06481551 0,08339365 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06481551 0,08334908 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06481551 0,08330455 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06481551 0,08326008 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,06481551 0,08321565 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06481551 0,08317126 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06481551 0,08312693 ! ovulation cycle process GO:0022602 49 31 0,000 0,06481551 0,08308264 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06481551 0,0830384 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06481551 0,08299421 ! peptide transport GO:0015833 55 31 0,000 0,06481551 0,08295006 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,06481551 0,08290597 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06481551 0,08286191 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06481551 0,08281791 ! mesoderm formation GO:0001707 69 31 0,000 0,06481551 0,08277395 ! natural killer cell activation GO:0030101 45 31 0,000 0,06481551 0,08273004 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06481551 0,08268617 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06481551 0,08264235 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06481551 0,08259858 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06481551 0,08255486 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06481551 0,08251118 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06683595 0,08503824 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06683595 0,08499329 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06683595 0,08494839 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06683595 0,08490354 ! cholesterol transport GO:0030301 56 32 0,000 0,06683595 0,08485873 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06683595 0,08481398 ! spliceosome assembly GO:0000245 67 32 0,000 0,06683595 0,08476927 ! spindle organization GO:0007051 46 32 0,000 0,06683595 0,08472461 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06683595 0,08467999 ! metanephros development GO:0001656 74 32 0,000 0,06683595 0,08463542 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06683595 0,0845909 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06683595 0,08454643 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06683595 0,084502 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06683595 0,08445762 ! muscle cell development GO:0055001 49 32 0,000 0,06683595 0,08441328 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06683595 0,08436899 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06683595 0,08432475 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,06683595 0,08428056 ! ovulation cycle GO:0042698 51 32 0,000 0,06683595 0,08423641 ! peripheral nervous system development GO:0007422 64 32 0,000 0,06683595 0,08419231 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06683595 0,08414825 ! hindbrain development GO:0030902 61 32 0,000 0,06683595 0,08410424 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06683595 0,08406027 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06683595 0,08401635 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06683595 0,08397248 ! gene silencing GO:0016458 65 32 0,000 0,06683595 0,08392865 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0688521 0,08641531 ! post-embryonic development GO:0009791 69 33 0,000 0,0688521 0,08637025 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0688521 0,08632524 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0688521 0,08628028 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0688521 0,08623537 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0688521 0,0861905 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0688521 0,08614568 ! cell fate specification GO:0001708 52 33 0,000 0,0688521 0,08610091 ! sterol transport GO:0015918 57 33 0,000 0,0688521 0,08605618 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0688521 0,0860115 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0688521 0,08596686 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0688521 0,08592227 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0688521 0,08587773 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0688521 0,08583323 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07086395 0,08829553 ! glial cell differentiation GO:0010001 63 34 0,000 0,07086395 0,08824983 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07086395 0,08820417 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07086395 0,08815856 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07086395 0,088113 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,07086395 0,08806749 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07086395 0,08802203 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07086395 0,08797661 ! spermatid development GO:0007286 63 34 0,000 0,07086395 0,08793123 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07086395 0,08788591 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07086395 0,08784063 ! placenta development GO:0001890 53 34 0,000 0,07086395 0,0877954 ! regulation of muscle development GO:0048634 70 35 0,000 0,07287152 0,09023617 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07287152 0,09018976 ! negative regulation of secretion GO:0051048 63 35 0,000 0,07287152 0,09014339 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,07287152 0,09009706 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07287152 0,09005079 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,07287152 0,09000456 ! odontogenesis GO:0042476 66 35 0,000 0,07287152 0,08995838 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07287152 0,08991225 ! female gonad development GO:0008585 58 35 0,000 0,07287152 0,08986616 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,07287152 0,08982013 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,07287152 0,08977414 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,07287152 0,08972819 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,07287152 0,08968229 ! cytokine production GO:0001816 59 35 0,000 0,07287152 0,08963644 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,07287152 0,08959064 ! neural tube formation GO:0001841 67 35 0,000 0,07287152 0,08954489 ! vesicle localization GO:0051648 64 35 0,000 0,07287152 0,08949918 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07487483 0,09191267 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07487483 0,0918658 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07487483 0,09181898 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07487483 0,0917722 ! cell junction organization GO:0034330 86 36 0,000 0,07487483 0,09172547 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07487483 0,0916788 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07487483 0,09163216 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07487483 0,09158558 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07487483 0,09153904 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07487483 0,09149255 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07487483 0,09144611 ! aerobic respiration GO:0009060 55 36 0,000 0,07487483 0,09139971 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,07487483 0,09135336 ! embryonic organ development GO:0048568 57 36 0,000 0,07487483 0,09130706 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07487483 0,09126081 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07487483 0,0912146 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07687387 0,09360249 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07687387 0,09355515 ! meiosis I GO:0007127 65 37 0,000 0,07687387 0,09350785 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07687387 0,0934606 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07687387 0,0934134 ! organic anion transport GO:0015711 68 37 0,000 0,07687387 0,09336624 ! tissue remodeling GO:0048771 76 37 0,000 0,07687387 0,09331913 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07687387 0,09327207 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07687387 0,09322506 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,07687387 0,0931781 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07687387 0,09313118 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07687387 0,09308431 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07687387 0,09303749 ! pigment metabolic process GO:0042440 80 37 0,000 0,07687387 0,09299071 ! spermatid differentiation GO:0048515 66 37 0,000 0,07687387 0,09294398 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,07886865 0,09530788 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,07886865 0,09526003 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07886865 0,09521223 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07886865 0,09516448 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07886865 0,09511678 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07886865 0,09506913 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,07886865 0,09502152 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07886865 0,09497396 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07886865 0,09492645 ! lipid homeostasis GO:0055088 67 38 0,000 0,07886865 0,09487899 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07886865 0,09483158 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,07886865 0,09478421 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07886865 0,09473689 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07886865 0,09468961 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,07886865 0,09464238 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07886865 0,09459521 ! glucan metabolic process GO:0044042 62 38 0,000 0,07886865 0,09454807 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,0808592 0,09688607 ! mammary gland development GO:0030879 86 39 0,000 0,0808592 0,09683784 ! learning GO:0007612 77 39 0,000 0,0808592 0,09678967 ! ear morphogenesis GO:0042471 60 39 0,000 0,0808592 0,09674154 ! organic ether metabolic process GO:0018904 55 39 0,000 0,0808592 0,09669345 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,0808592 0,09664542 ! segmentation GO:0035282 67 39 0,000 0,0808592 0,09659743 ! ion transmembrane transport GO:0034220 66 39 0,000 0,0808592 0,09654949 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,0808592 0,0965016 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,0808592 0,09645376 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,0808592 0,09640596 ! RNA modification GO:0009451 57 39 0,000 0,0808592 0,09635821 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,0808592 0,09631051 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,0828455 0,09862755 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,0828455 0,09857878 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,0828455 0,09853005 ! feeding behavior GO:0007631 59 40 0,000 0,0828455 0,09848137 ! negative regulation of binding GO:0051100 72 40 0,000 0,0828455 0,09843273 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,0828455 0,09838415 ! mesenchymal cell development GO:0014031 87 40 0,000 0,0828455 0,09833561 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,0828455 0,09828712 ! maintenance of protein location GO:0045185 91 40 0,000 0,0828455 0,09823868 ! cytokinesis GO:0000910 72 40 0,000 0,0828455 0,09819029 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08482758 0,10048999 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08482758 0,10044054 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08482758 0,10039113 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08482758 0,10034177 ! gliogenesis GO:0042063 88 41 0,000 0,08482758 0,10029247 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08482758 0,10024321 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08482758 0,100194 ! T cell differentiation GO:0030217 81 41 0,000 0,08482758 0,10014483 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08482758 0,10009572 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08482758 0,10004665 ! female gamete generation GO:0007292 61 41 0,000 0,08482758 0,09999763 ! polyol metabolic process GO:0019751 66 41 0,000 0,08482758 0,09994866 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,08482758 0,09989974 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08680545 0,10217902 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08680545 0,10212905 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08680545 0,10207913 ! regulation of tube size GO:0035150 71 42 0,000 0,08680545 0,10202927 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08680545 0,10197945 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08680545 0,10192968 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08680545 0,10187995 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08680545 0,10183028 ! neuron migration GO:0001764 79 42 0,000 0,08680545 0,10178066 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08680545 0,10173108 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08680545 0,10168155 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0887791 0,10394283 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0887791 0,10389228 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0887791 0,10384177 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0887791 0,10379131 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,0887791 0,1037409 ! glucose transport GO:0015758 65 43 0,000 0,0887791 0,10369054 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,0887791 0,10364023 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0887791 0,10358997 ! neural tube development GO:0021915 77 43 0,000 0,0887791 0,10353976 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,0887791 0,10348959 ! striated muscle contraction GO:0006941 77 43 0,000 0,0887791 0,10343948 ! phagocytosis GO:0006909 90 43 0,000 0,0887791 0,10338941 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0887791 0,10333939 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09074856 0,10558077 ! hexose transport GO:0008645 67 44 0,000 0,09074856 0,10552974 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09074856 0,10547876 ! male sex differentiation GO:0046661 76 44 0,000 0,09074856 0,10542782 ! double-strand break repair GO:0006302 81 44 0,000 0,09074856 0,10537694 ! biopolymer methylation GO:0043414 84 44 0,000 0,09074856 0,10532611 ! B cell differentiation GO:0030183 107 44 0,000 0,09074856 0,10527533 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09074856 0,10522459 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09074856 0,1051739 ! developmental growth GO:0048589 82 44 0,000 0,09074856 0,10512327 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09074856 0,10507268 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09271382 0,10729651 ! glycolysis GO:0006096 65 45 0,000 0,09271382 0,10724493 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,09271382 0,10719339 ! leukocyte migration GO:0050900 68 45 0,000 0,09271382 0,10714191 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09271382 0,10709047 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,09271382 0,10703908 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09271382 0,10698774 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09271382 0,10693646 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09271382 0,10688522 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09271382 0,10683403 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09271382 0,10678289 ! cell growth GO:0016049 84 45 0,000 0,09271382 0,10673179 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,0946749 0,10893726 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0946749 0,10888518 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0946749 0,10883316 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0946749 0,10878119 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0946749 0,10872926 ! pigmentation GO:0043473 100 46 0,000 0,0946749 0,10867739 ! positive regulation of defense response GO:0031349 76 47 0,000 0,09663181 0,11087083 ! response to calcium ion GO:0051592 81 47 0,000 0,09663181 0,11081798 ! endosome transport GO:0016197 108 47 0,000 0,09663181 0,11076518 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,09663181 0,11071244 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,09663181 0,11065974 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,09663181 0,1106071 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,09663181 0,1105545 ! JNK cascade GO:0007254 91 47 0,000 0,09663181 0,11050196 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,09663181 0,11044946 ! methylation GO:0032259 90 47 0,000 0,09663181 0,11039702 ! positive regulation of cell cycle GO:0045787 89 48 0,000 0,09858455 0,11257447 ! Notch signaling pathway GO:0007219 96 48 0,000 0,09858455 0,11252107 ! cellular component disassembly GO:0022411 86 48 0,000 0,09858455 0,11246772 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,09858455 0,11241442 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,09858455 0,11236116 ! activation of caspase activity GO:0006919 84 48 0,000 0,09858455 0,11230796 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,09858455 0,11225481 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,09858455 0,11220171 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,09858455 0,11214866 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,09858455 0,11209566 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10053313 0,1142573 ! regulation of action potential GO:0001508 95 49 0,000 0,10053313 0,11420336 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10053313 0,11414946 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10053313 0,11409562 ! regulation of ion transport GO:0043269 77 49 0,000 0,10053313 0,11404183 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10053313 0,11398808 ! peptide metabolic process GO:0006518 76 49 0,000 0,10053313 0,11393439 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10053313 0,11388075 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10053313 0,11382716 ! endocrine system development GO:0035270 104 49 0,000 0,10053313 0,11377362 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10053313 0,11372013 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10053313 0,11366669 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10053313 0,1136133 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10053313 0,11355996 ! neuromuscular process GO:0050905 99 50 0,000 0,10247757 0,11570203 ! regulation of ossification GO:0030278 117 50 0,000 0,10247757 0,11564776 ! inner ear development GO:0048839 79 50 0,000 0,10247757 0,11559354 ! histone modification GO:0016570 91 50 0,000 0,10247757 0,11553938 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10247757 0,11548526 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,10247757 0,11543119 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10247757 0,11537718 ! positive regulation of binding GO:0051099 78 51 0,000 0,10441787 0,11750673 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10441787 0,11745179 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10441787 0,11739691 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10441787 0,11734208 ! excretion GO:0007588 83 51 0,000 0,10441787 0,1172873 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10441787 0,11723257 ! chromatin remodeling GO:0006338 109 51 0,000 0,10441787 0,11717789 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10441787 0,11712326 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10441787 0,11706868 ! vesicle organization GO:0016050 107 51 0,000 0,10441787 0,11701415 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,10441787 0,11695968 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 0,000 0,10441787 0,11690525 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10441787 0,11685088 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,10635404 0,11896226 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,10635404 0,11890698 ! membrane fusion GO:0006944 110 52 0,000 0,10635404 0,11885175 ! positive regulation of growth GO:0045927 90 52 0,000 0,10635404 0,11879657 ! covalent chromatin modification GO:0016569 101 52 0,000 0,10635404 0,11874144 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,10635404 0,11868637 ! amino acid activation GO:0043038 92 52 0,000 0,10635404 0,11863134 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,10635404 0,11857637 ! synapse organization GO:0050808 85 52 0,000 0,10635404 0,11852145 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10828608 0,12061866 ! RNA catabolic process GO:0006401 93 53 0,000 0,10828608 0,12056285 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10828608 0,12050708 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,10828608 0,12045137 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10828608 0,12039571 ! cell maturation GO:0048469 100 53 0,000 0,10828608 0,1203401 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,10828608 0,12028454 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,10828608 0,12022903 ! response to UV GO:0009411 104 53 0,000 0,10828608 0,12017358 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,11021402 0,12225677 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11021402 0,12220043 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11021402 0,12214414 ! cell recognition GO:0008037 85 54 0,000 0,11021402 0,1220879 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11021402 0,12203172 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11021402 0,12197559 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11021402 0,12191951 ! chloride transport GO:0006821 90 55 0,000 0,11213785 0,12399065 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11213785 0,1239337 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,11213785 0,12387679 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,11213785 0,12381994 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11213785 0,12376315 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,11213785 0,1237064 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11213785 0,12364971 ! aging GO:0007568 103 55 0,000 0,11213785 0,12359306 ! gastrulation GO:0007369 112 55 0,000 0,11213785 0,12353647 ! heart morphogenesis GO:0003007 97 55 0,000 0,11213785 0,12347994 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11213785 0,12342345 ! RNA elongation GO:0006354 79 55 0,000 0,11213785 0,12336701 ! nuclear export GO:0051168 97 55 0,000 0,11213785 0,12331063 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,11213785 0,1232543 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11405758 0,12530709 ! sensory perception of smell GO:0007608 80 56 0,000 0,11405758 0,1252499 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,11405758 0,12519276 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11405758 0,12513568 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,11405758 0,12507864 ! regulation of DNA replication GO:0006275 101 56 0,000 0,11405758 0,12502166 ! proton transport GO:0015992 94 56 0,000 0,11405758 0,12496473 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,11405758 0,12490785 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,11597323 0,12694795 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,11597323 0,12689022 ! muscle fiber development GO:0048747 112 57 0,000 0,11597323 0,12683254 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,11597323 0,12677491 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,11597323 0,12671734 ! maintenance of location GO:0051235 118 57 0,000 0,11597323 0,12665982 ! hydrogen transport GO:0006818 97 58 0,000 0,1178848 0,12868912 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,1178848 0,12863076 ! regulation of endocytosis GO:0030100 91 58 0,000 0,1178848 0,12857245 ! adult behavior GO:0030534 99 58 0,000 0,1178848 0,12851419 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,1178848 0,12845599 ! positive regulation of secretion GO:0051047 95 59 0,000 0,11979229 0,13047544 ! regulation of cellular component size GO:0032535 109 59 0,000 0,11979229 0,13041641 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,11979229 0,13035742 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,11979229 0,13029849 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,11979229 0,13023961 ! DNA catabolic process GO:0006308 86 59 0,000 0,11979229 0,13018078 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,11979229 0,13012201 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12169573 0,13212993 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12169573 0,13207033 ! regulation of heart contraction GO:0008016 110 60 0,000 0,12169573 0,13201079 ! camera-type eye development GO:0043010 116 60 0,000 0,12169573 0,1319513 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,12169573 0,13189186 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,12169573 0,13183247 ! kidney development GO:0001822 122 60 0,000 0,12169573 0,13177314 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12359511 0,13376961 ! mesoderm development GO:0007498 119 61 0,000 0,12359511 0,13370946 ! tRNA processing GO:0008033 89 61 0,000 0,12359511 0,13364937 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12359511 0,13358933 ! ear development GO:0043583 103 62 0,000 0,12549045 0,13557702 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12549045 0,13551617 ! gonad development GO:0008406 98 62 0,000 0,12549045 0,13545537 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,12549045 0,13539463 ! detection of external stimulus GO:0009581 91 63 0,000 0,12738176 0,1373736 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12738176 0,13731205 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,12738176 0,13725056 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,12926903 0,13922171 ! cell redox homeostasis GO:0045454 102 64 0,000 0,12926903 0,13915941 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,12926903 0,13909718 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,12926903 0,139035 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,12926903 0,13897287 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,12926903 0,1389108 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13115229 0,14087161 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13115229 0,14080875 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,13115229 0,14074594 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,13115229 0,1406832 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13303153 0,14263542 ! actin filament organization GO:0007015 148 66 0,000 0,13303153 0,14257188 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13303153 0,1425084 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13303153 0,14244498 ! secondary metabolic process GO:0019748 116 66 0,000 0,13303153 0,14238162 ! developmental maturation GO:0021700 116 66 0,000 0,13303153 0,14231831 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13490678 0,14426032 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,13490678 0,14419623 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,13490678 0,1441322 ! lung development GO:0030324 144 67 0,000 0,13490678 0,14406822 ! chromosome segregation GO:0007059 113 67 0,000 0,13490678 0,14400431 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13490678 0,14394045 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,13490678 0,14387664 ! hexose catabolic process GO:0019320 104 67 0,000 0,13490678 0,1438129 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,13490678 0,14374921 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,13490678 0,14368557 ! adaptive immune response GO:0002250 119 67 0,000 0,13490678 0,143622 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,13490678 0,14355847 ! amino acid transport GO:0006865 125 68 0,000 0,13677803 0,14548538 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,13677803 0,14542109 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,13677803 0,14535686 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,13677803 0,14529269 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,13677803 0,14522857 ! regulation of lipase activity GO:0060191 130 68 0,000 0,13677803 0,14516451 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,13677803 0,1451005 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,13677803 0,14503655 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,13864529 0,1469518 ! negative regulation of cell size GO:0045792 134 69 0,000 0,13864529 0,14688709 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,13864529 0,14682244 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,13864529 0,14675784 ! urogenital system development GO:0001655 137 69 0,000 0,13864529 0,1466933 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,13864529 0,14662882 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,13864529 0,1465644 ! antigen processing and presentation GO:0019882 104 69 0,000 0,13864529 0,14650003 ! appendage morphogenesis GO:0035107 135 70 0,000 0,14050858 0,14840371 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,14050858 0,14833859 ! amine catabolic process GO:0009310 117 71 0,000 0,1423679 0,1502356 ! reproductive structure development GO:0048608 113 71 0,000 0,1423679 0,15016973 ! appendage development GO:0048736 136 71 0,000 0,1423679 0,15010393 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,1423679 0,15003818 ! B cell activation GO:0042113 160 71 0,000 0,1423679 0,14997249 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,1423679 0,14990686 ! regulation of immune effector process GO:0002697 137 71 0,000 0,1423679 0,14984128 ! acute inflammatory response GO:0002526 113 72 0,000 0,14422326 0,15172766 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14422326 0,15166134 ! carbohydrate transport GO:0008643 110 72 0,000 0,14422326 0,15159509 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14422326 0,15152889 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14422326 0,15146275 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,14422326 0,15139666 ! respiratory system development GO:0060541 153 72 0,000 0,14422326 0,15133064 ! learning or memory GO:0007611 147 73 0,000 0,14607466 0,15320647 ! regulation of blood pressure GO:0008217 125 73 0,000 0,14607466 0,15313971 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,14607466 0,15307301 ! axon guidance GO:0007411 139 73 0,000 0,14607466 0,15300637 ! fertilization GO:0009566 90 73 0,000 0,14607466 0,15293979 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,14792212 0,15480671 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,14792212 0,1547394 ! neurotransmitter transport GO:0006836 123 74 0,000 0,14792212 0,15467216 ! meiosis GO:0007126 121 74 0,000 0,14792212 0,15460497 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,14792212 0,15453783 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,14792212 0,15447076 ! eye development GO:0001654 143 74 0,000 0,14792212 0,15440374 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,14976565 0,15626026 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,14976565 0,15619253 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,14976565 0,15612485 ! meiotic cell cycle GO:0051321 122 75 0,000 0,14976565 0,15605724 ! rhythmic process GO:0048511 128 75 0,000 0,14976565 0,15598968 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,14976565 0,15592218 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,15160525 0,15776913 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,15160525 0,15770092 ! defense response to bacterium GO:0042742 89 76 0,000 0,15160525 0,15763277 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,15160525 0,15756468 ! regulation of catabolic process GO:0009894 161 76 0,000 0,15160525 0,15749665 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15344093 0,15933486 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15344093 0,15926612 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15344093 0,15919745 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,15344093 0,15912883 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,1552727 0,16095912 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,1552727 0,1608898 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,1552727 0,16082054 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,15710056 0,1626437 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,15710056 0,16257375 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,15710056 0,16250385 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,15710056 0,16243402 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,15710056 0,16236424 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,15710056 0,16229453 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,15892454 0,16410834 ! response to metal ion GO:0010038 140 80 0,000 0,15892454 0,16403794 ! muscle cell differentiation GO:0042692 159 80 0,000 0,15892454 0,1639676 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,15892454 0,16389731 ! inorganic anion transport GO:0015698 138 80 0,000 0,15892454 0,16382709 ! T cell activation GO:0042110 168 81 0,000 0,16074462 0,16563236 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,16074462 0,16556146 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 0,000 0,16074462 0,16549061 ! digestion GO:0007586 112 81 0,000 0,16074462 0,16541983 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,16074462 0,16534911 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16074462 0,16527844 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,16074462 0,16520784 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16256083 0,16700314 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16256083 0,16693186 ! response to drug GO:0042493 143 82 0,000 0,16256083 0,16686065 ! response to nutrient GO:0007584 125 82 0,000 0,16256083 0,16678949 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16256083 0,1667184 ! response to oxygen levels GO:0070482 176 83 0,000 0,16437317 0,16850526 ! regulation of lyase activity GO:0051339 160 83 0,000 0,16437317 0,16843349 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,16618164 0,17021415 ! negative regulation of transport GO:0051051 153 84 0,000 0,16618164 0,17014171 ! negative regulation of growth GO:0045926 155 84 0,000 0,16618164 0,17006934 ! regulation of ligase activity GO:0051340 142 84 0,000 0,16618164 0,16999704 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,16618164 0,16992479 ! nucleosome assembly GO:0006334 122 85 0,000 0,16798626 0,17169709 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,16798626 0,17162418 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,16798626 0,17155134 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,16978704 0,17331676 ! response to inorganic substance GO:0010035 153 86 0,000 0,16978704 0,17324326 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,16978704 0,17316982 ! chromatin assembly GO:0031497 124 86 0,000 0,16978704 0,17309645 ! tube morphogenesis GO:0035239 176 86 0,000 0,16978704 0,17302313 ! alcohol catabolic process GO:0046164 130 86 0,000 0,16978704 0,17294988 ! amine transport GO:0015837 155 86 0,000 0,16978704 0,17287669 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,17158398 0,17463242 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17158398 0,17455858 ! cellular respiration GO:0045333 135 88 0,000 0,17337708 0,17630823 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,17337708 0,17623374 ! regulation of DNA binding GO:0051101 155 88 0,000 0,17337708 0,17615932 ! gland development GO:0048732 206 88 0,000 0,17337708 0,17608496 ! regulation of neurological system process GO:0031644 148 88 0,000 0,17337708 0,17601066 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,17337708 0,17593643 ! cellular defense response GO:0006968 114 89 0,000 0,17516637 0,17767719 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,17516637 0,17760231 ! ossification GO:0001503 188 90 0,000 0,17695184 0,17933704 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,17695184 0,17926153 ! sex differentiation GO:0007548 145 90 0,000 0,17695184 0,17918608 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,17695184 0,1791107 ! bone development GO:0060348 189 91 0,000 0,17873351 0,18083803 ! sterol metabolic process GO:0016125 152 91 0,000 0,17873351 0,18076201 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,17873351 0,18068606 ! regulation of defense response GO:0031347 149 92 0,000 0,18051138 0,18240671 ! nucleosome organization GO:0034728 138 92 0,000 0,18051138 0,18233014 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18051138 0,18225362 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18051138 0,18217717 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,18228546 0,18389049 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,18228546 0,18381342 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,18228546 0,18373641 ! regulation of membrane potential GO:0042391 164 93 0,000 0,18228546 0,18365947 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,18405576 0,18536549 ! transcription initiation GO:0006352 153 94 0,000 0,18405576 0,18528793 ! regulation of T cell activation GO:0050863 158 94 0,000 0,18405576 0,18521044 ! forebrain development GO:0030900 188 95 0,000 0,18582229 0,18690987 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,18582229 0,18683177 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,18758504 0,18852532 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,18758504 0,1884466 ! positive regulation of immune response GO:0050778 156 96 0,000 0,18758504 0,18836795 ! detection of stimulus GO:0051606 151 96 0,000 0,18758504 0,18828937 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,18934405 0,18997572 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,18934405 0,18989653 ! protein ubiquitination GO:0016567 217 97 0,000 0,18934405 0,18981741 ! response to virus GO:0009615 160 98 0,000 0,1910993 0,19149725 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1910993 0,19141753 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,1910993 0,19133787 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,19285081 0,19301125 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,19285081 0,19293099 ! cell cycle arrest GO:0007050 213 100 0,000 0,19459858 0,19459858