pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/669-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! chloride transport GO:0006821 67 48 5,000 8,006E-10 1,841E-06 ! inorganic anion transport GO:0015698 93 68 5,000 6,92E-09 7,958E-06 ! G1 phase GO:0051318 27 16 2,000 5,203E-06 3,989E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 8,963E-06 5,154E-03 ! osteoblast differentiation GO:0001649 40 23 2,000 1,628E-05 7,491E-03 ! ossification GO:0001503 134 82 3,000 2,939E-05 0,01126678 GO:0060348|bone development, ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 3,546E-05 0,01165226 ! interphase GO:0051325 159 88 3,000 3,882E-05 0,01116123 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 1,000 4,582E-05 0,0117091 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 1,000 4,582E-05 0,01053819 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 6,863E-05 0,01435053 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! hyperosmotic response GO:0006972 8 6 1,000 6,863E-05 0,01315466 ! male sex determination GO:0030238 9 6 1,000 6,863E-05 0,01214276 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 1,000 6,863E-05 0,01127542 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 6,863E-05 0,01052372 ! midbrain development GO:0030901 6 6 1,000 6,863E-05 9,866E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 6,863E-05 9,286E-03 ! striated muscle cell differentiation GO:0051146 54 38 2,000 7,584E-05 9,691E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 8,204E-05 9,931E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 9,595E-05 0,01103475 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 9,595E-05 0,01050928 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 9,595E-05 0,01003159 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 9,595E-05 9,595E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,101E-04 0,01055299 ! negative regulation of cell migration GO:0030336 92 44 2,000 1,18E-04 0,01085586 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 1,262E-04 0,01116716 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,278E-04 0,01088356 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 1,000 1,278E-04 0,01049486 ! regulation of smoothened signaling pathway GO:0008589 13 8 1,000 1,278E-04 0,01013297 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,278E-04 9,795E-03 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,278E-04 9,479E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 1,278E-04 9,183E-03 ! cell volume homeostasis GO:0006884 13 9 1,000 1,64E-04 0,01143323 ! negative regulation of BMP signaling pathway GO:0030514 13 9 1,000 1,64E-04 0,01109696 ! localization within membrane GO:0051668 15 9 1,000 1,64E-04 0,01077991 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 1,836E-04 0,01173032 ! negative regulation of cell motion GO:0051271 104 51 2,000 1,836E-04 0,01141328 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 2,048E-04 0,01239405 ! embryonic gut development GO:0048566 11 10 1,000 2,048E-04 0,01207625 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,499E-04 0,01437113 ! detection of mechanical stimulus GO:0050982 15 11 1,000 2,499E-04 0,01402062 ! chondrocyte differentiation GO:0002062 17 11 1,000 2,499E-04 0,01368679 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 2,692E-04 0,01439934 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 3,439E-04 0,01797531 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 3,535E-04 0,01806668 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,535E-04 0,01767393 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 4,118E-04 0,0201532 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 4,691E-04 0,02247651 ! response to osmotic stress GO:0006970 22 15 1,000 4,745E-04 0,02227399 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 4,745E-04 0,02182851 ! muscle cell differentiation GO:0042692 104 71 2,000 4,89E-04 0,0220546 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 1,000 5,416E-04 0,02395449 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 6,129E-04 0,02659968 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 6,129E-04 0,0261071 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 1,000 6,886E-04 0,02879696 ! estrogen receptor signaling pathway GO:0030520 30 18 1,000 6,886E-04 0,02828273 ! gut development GO:0048565 26 18 1,000 6,886E-04 0,02778654 ! sex determination GO:0007530 29 19 1,000 7,686E-04 0,03047829 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 7,686E-04 0,02996171 ! sarcomere organization GO:0045214 23 19 1,000 7,686E-04 0,02946235 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 7,686E-04 0,02897936 ! transcription initiation GO:0006352 118 85 2,000 8,276E-04 0,03070074 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 8,528E-04 0,03113437 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 8,528E-04 0,0306479 ! positive regulation of osteoblast differentiation GO:0045669 33 20 1,000 8,528E-04 0,03017639 ! collagen catabolic process GO:0030574 25 20 1,000 8,528E-04 0,02971917 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 9,413E-04 0,03231292 ! embryonic pattern specification GO:0009880 31 23 1,000 1,131E-03 0,0382519 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 1,131E-03 0,03769753 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 1,232E-03 0,04048157 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 1,232E-03 0,03991141 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 1,232E-03 0,03935709 ! male gonad development GO:0008584 33 25 1,000 1,337E-03 0,04213565 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 1,337E-03 0,04156625 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,447E-03 0,04436889 ! multicellular organismal catabolic process GO:0044243 32 26 1,000 1,447E-03 0,04378509 ! inner ear morphogenesis GO:0042472 35 27 1,000 1,56E-03 0,04660988 ! myofibril assembly GO:0030239 36 27 1,000 1,56E-03 0,04601232 GO:0055002|striated muscle cell development, ! erythrocyte differentiation GO:0030218 38 28 1,000 1,678E-03 0,04885754 ! mesoderm formation GO:0001707 46 28 1,000 1,678E-03 0,04824682 ! BMP signaling pathway GO:0030509 40 28 1,000 1,678E-03 0,04765118 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 1,8E-03 0,05048756 ! muscle cell development GO:0055001 38 29 1,000 1,8E-03 0,04987927 ! formation of primary germ layer GO:0001704 48 29 1,000 1,8E-03 0,04928547 ! collagen metabolic process GO:0032963 40 30 1,000 1,926E-03 0,05211322 ! hindbrain development GO:0030902 45 30 1,000 1,926E-03 0,05150725 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 2,056E-03 0,05435215 ! mesoderm morphogenesis GO:0048332 49 31 1,000 2,056E-03 0,05373451 ! response to mechanical stimulus GO:0009612 43 31 1,000 2,056E-03 0,05313076 ! calcium-mediated signaling GO:0019722 50 32 1,000 2,19E-03 0,05596645 ! ear morphogenesis GO:0042471 42 33 1,000 2,328E-03 0,05884191 ! actomyosin structure organization GO:0031032 43 33 1,000 2,328E-03 0,05820233 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 2,328E-03 0,05757649 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 2,328E-03 0,05696398 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 2,47E-03 0,05980524 ! erythrocyte homeostasis GO:0034101 45 34 1,000 2,47E-03 0,05918227 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 2,47E-03 0,05857214 ! embryonic organ development GO:0048568 45 34 1,000 2,47E-03 0,05797446 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 2,616E-03 0,06078375 ! protein homooligomerization GO:0051260 52 35 1,000 2,616E-03 0,06017592 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 3,079E-03 0,07010638 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 3,241E-03 0,07307145 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 3,241E-03 0,07236202 ! male sex differentiation GO:0046661 53 39 1,000 3,241E-03 0,07166623 ! cell growth GO:0016049 61 39 1,000 3,241E-03 0,0709837 ! response to calcium ion GO:0051592 58 40 1,000 3,406E-03 0,07391365 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 3,406E-03 0,07322287 ! inner ear development GO:0048839 57 40 1,000 3,406E-03 0,07254488 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 3,406E-03 0,07187933 ! positive regulation of protein transport GO:0051222 55 40 1,000 3,406E-03 0,07122588 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 3,75E-03 0,07770137 ! embryonic skeletal system development GO:0048706 56 42 1,000 3,75E-03 0,07700761 ! detection of abiotic stimulus GO:0009582 58 44 1,000 4,109E-03 0,08363231 ! positive regulation of cell cycle GO:0045787 77 45 1,000 4,294E-03 0,08663599 ! regulation of ossification GO:0030278 71 46 1,000 4,483E-03 0,08966381 ! response to UV GO:0009411 75 46 1,000 4,483E-03 0,08889084 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 1,000 4,676E-03 0,09192237 ! gastrulation GO:0007369 73 48 1,000 4,873E-03 0,09497631 ! RNA elongation GO:0006354 62 49 1,000 5,073E-03 0,09805178 ! regulation of intracellular transport GO:0032386 78 49 1,000 5,073E-03 0,09723468 ! cartilage development GO:0051216 70 49 1,000 5,073E-03 0,09643109 ! ear development GO:0043583 72 50 1,000 5,277E-03 0,09948975 ! activation of phospholipase C activity GO:0007202 87 51 1,000 5,485E-03 0,10256855 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of cell migration GO:0030335 92 51 1,000 5,485E-03 0,10174138 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 5,697E-03 0,10482136 ! regulation of bone remodeling GO:0046850 90 53 1,000 5,912E-03 0,10792006 ! regulation of phospholipase activity GO:0010517 90 54 1,000 6,131E-03 0,11103674 ! detection of external stimulus GO:0009581 66 54 1,000 6,131E-03 0,11016926 ! regulation of tissue remodeling GO:0034103 91 54 1,000 6,131E-03 0,10931524 ! positive regulation of lipase activity GO:0060193 90 54 1,000 6,131E-03 0,10847435 ! mesoderm development GO:0007498 76 55 1,000 6,354E-03 0,1115561 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 6,58E-03 0,11465484 ! positive regulation of cell motion GO:0051272 99 56 1,000 6,58E-03 0,11379277 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 6,81E-03 0,11689104 ! developmental maturation GO:0021700 75 57 1,000 6,81E-03 0,11602518 ! gonad development GO:0008406 79 57 1,000 6,81E-03 0,11517206 ! negative regulation of kinase activity GO:0033673 100 58 1,000 7,044E-03 0,11825324 ! lung development GO:0030324 94 59 1,000 7,281E-03 0,12134988 ! myeloid cell differentiation GO:0030099 85 59 1,000 7,281E-03 0,12047686 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 7,522E-03 0,12357239 GO:0035113|embryonic appendage morphogenesis, ! homeostasis of number of cells GO:0048872 84 61 1,000 7,766E-03 0,12668233 ! negative regulation of transferase activity GO:0051348 105 61 1,000 7,766E-03 0,1257902 ! negative regulation of cell growth GO:0030308 106 62 1,000 8,014E-03 0,12889839 ! respiratory tube development GO:0030323 99 62 1,000 8,014E-03 0,12800326 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 8,266E-03 0,13110952 ! regulation of lipase activity GO:0060191 109 63 1,000 8,266E-03 0,13021151 ! cell cycle checkpoint GO:0000075 108 64 1,000 8,521E-03 0,13331569 ! negative regulation of cell size GO:0045792 108 64 1,000 8,521E-03 0,13241491 ! appendage morphogenesis GO:0035107 93 64 1,000 8,521E-03 0,13152622 GO:0035108|limb morphogenesis, ! respiratory system development GO:0060541 100 64 1,000 8,521E-03 0,13064938 ! reproductive structure development GO:0048608 90 65 1,000 8,779E-03 0,13372193 ! regulation of caspase activity GO:0043281 97 65 1,000 8,779E-03 0,13284218 ! appendage development GO:0048736 94 65 1,000 8,779E-03 0,13197393 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 8,779E-03 0,13111696 ! protein oligomerization GO:0051259 100 65 1,000 8,779E-03 0,13027104 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 9,307E-03 0,13721354 ! development of primary sexual characteristics GO:0045137 92 68 1,000 9,576E-03 0,14027985 ! response to metal ion GO:0010038 103 70 1,000 0,01012389 0,14737314 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,01012389 0,14644627 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,01012389 0,14553098 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,01068584 0,15265486 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,01068584 0,15171255 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,01068584 0,1507818 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01082241 0,15177769 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01082241 0,15085782 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01082241 0,14994904 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01082241 0,14905114 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01082241 0,14816393 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01082241 0,14728722 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01082241 0,14642083 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01082241 0,14556456 ! sleep GO:0030431 11 5 0,000 0,01082241 0,14471826 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01082241 0,14388174 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01082241 0,14305483 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01082241 0,14223737 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01082241 0,14142921 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01082241 0,14063017 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01082241 0,13984012 ! tongue development GO:0043586 6 5 0,000 0,01082241 0,13905889 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01082241 0,13828634 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01082241 0,13752232 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01082241 0,13676671 ! cobalt ion transport GO:0006824 9 5 0,000 0,01082241 0,13601935 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01082241 0,13528011 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01082241 0,13454887 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01082241 0,13382549 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01082241 0,13310984 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01082241 0,13240181 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01082241 0,13170127 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01082241 0,13100811 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01082241 0,1303222 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01082241 0,12964344 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01082241 0,12897171 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01082241 0,12830691 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01082241 0,12764893 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01082241 0,12699766 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01082241 0,126353 ! malate metabolic process GO:0006108 7 5 0,000 0,01082241 0,12571485 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01082241 0,12508312 ! behavioral response to pain GO:0048266 7 5 0,000 0,01082241 0,1244577 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01082241 0,12383851 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01082241 0,12322545 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01082241 0,12261843 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01082241 0,12201736 ! mating behavior GO:0007617 6 5 0,000 0,01082241 0,12142215 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01082241 0,12083272 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01082241 0,12024899 ! rhythmic behavior GO:0007622 12 5 0,000 0,01082241 0,11967087 ! copulation GO:0007620 7 5 0,000 0,01082241 0,11909828 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01082241 0,11853115 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01082241 0,11796939 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01082241 0,11741293 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01082241 0,11686169 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01082241 0,11631561 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01082241 0,11577461 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01082241 0,11523861 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01082241 0,11470756 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01082241 0,11418138 ! response to protozoan GO:0001562 9 5 0,000 0,01082241 0,11366 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01082241 0,11314337 ! lymph vessel development GO:0001945 7 5 0,000 0,01082241 0,11263141 ! endochondral ossification GO:0001958 12 5 0,000 0,01082241 0,11212406 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01082241 0,11162126 ! parathyroid gland development GO:0060017 8 5 0,000 0,01082241 0,11112295 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01082241 0,11062907 ! anagen GO:0042640 6 5 0,000 0,01082241 0,11013956 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01082241 0,10965436 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01082241 0,10917342 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01082241 0,10869668 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01082241 0,10822409 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01082241 0,10775559 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01082241 0,10729112 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01082241 0,10683065 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01082241 0,1063741 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01082241 0,10592145 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01082241 0,10547263 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01082241 0,1050276 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01082241 0,1045863 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01082241 0,10414871 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01082241 0,10371475 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01082241 0,1032844 ! ovulation GO:0030728 6 5 0,000 0,01082241 0,10285761 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01082241 0,10243432 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01082241 0,10201451 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01082241 0,10159812 ! response to pH GO:0009268 9 5 0,000 0,01082241 0,10118512 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01082241 0,10077547 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01082241 0,10036912 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01082241 0,09996603 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01082241 0,09956616 ! polyol catabolic process GO:0046174 7 5 0,000 0,01082241 0,09916948 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01082241 0,09877595 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01082241 0,09838554 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01082241 0,09799819 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01082241 0,09761388 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01082241 0,09723258 ! urea metabolic process GO:0019627 6 5 0,000 0,01082241 0,09685424 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01082241 0,09647884 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01082241 0,09610633 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01082241 0,09573669 ! neutrophil activation GO:0042119 5 5 0,000 0,01082241 0,09536989 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01082241 0,09500588 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01082241 0,09464464 ! response to food GO:0032094 5 5 0,000 0,01082241 0,09428614 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01082241 0,09393034 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01082241 0,09357722 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01082241 0,09322674 ! forebrain neuron development GO:0021884 7 5 0,000 0,01082241 0,09287888 ! melanosome organization GO:0032438 7 5 0,000 0,01082241 0,09253361 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01082241 0,09219089 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01082241 0,0918507 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01082241 0,09151302 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01082241 0,0911778 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01082241 0,09084504 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01082241 0,09051469 ! nucleoside transport GO:0015858 6 5 0,000 0,01082241 0,09018674 ! nucleoside salvage GO:0043174 7 5 0,000 0,01082241 0,08986116 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01082241 0,08953792 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01082241 0,08921699 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01082241 0,08889836 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01082241 0,08858199 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01082241 0,08826787 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01082241 0,08795597 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01082241 0,08764627 ! depyrimidination GO:0045008 8 5 0,000 0,01082241 0,08733874 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01082241 0,08703336 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01082241 0,08673011 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01082241 0,08642896 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01082241 0,0861299 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01082241 0,0858329 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01082241 0,08553794 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01082241 0,085245 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01082241 0,08495406 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01082241 0,0846651 ! monocyte differentiation GO:0030224 8 5 0,000 0,01082241 0,0843781 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01082241 0,08409304 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01082241 0,0838099 ! centrosome duplication GO:0051298 5 5 0,000 0,01082241 0,08352866 ! response to UV-C GO:0010225 6 5 0,000 0,01082241 0,0832493 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01082241 0,0829718 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01082241 0,08269615 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01082241 0,08242232 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01082241 0,0821503 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01082241 0,08188007 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01082241 0,08161161 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01082241 0,0813449 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01082241 0,08107994 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01082241 0,08081669 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01082241 0,08055515 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01082241 0,08029529 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01082241 0,08003711 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01082241 0,07978058 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01082241 0,07952569 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01082241 0,07927242 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01082241 0,07902076 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01082241 0,0787707 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01082241 0,07852221 ! neural tube patterning GO:0021532 6 5 0,000 0,01082241 0,07827528 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01082241 0,07802991 ! histone demethylation GO:0016577 9 5 0,000 0,01082241 0,07778606 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01082241 0,07754374 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01082241 0,07730292 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01082241 0,07706359 ! enteric nervous system development GO:0048484 8 5 0,000 0,01082241 0,07682574 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01082241 0,07658936 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01082241 0,07635442 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01082241 0,07612092 ! transcription termination GO:0006353 8 5 0,000 0,01082241 0,07588884 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01082241 0,07565818 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01082241 0,07542891 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01082241 0,07520103 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01082241 0,07497452 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01082241 0,07474937 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01082241 0,07452557 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01082241 0,07430311 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01082241 0,07408197 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01082241 0,07386214 ! apical protein localization GO:0045176 6 5 0,000 0,01082241 0,07364361 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01082241 0,07342637 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01082241 0,07321041 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01082241 0,07299572 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01082241 0,07278228 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01082241 0,07257009 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01082241 0,07235913 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01082241 0,07214939 ! glial cell migration GO:0008347 10 5 0,000 0,01082241 0,07194087 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01082241 0,07173355 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01082241 0,07152742 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01082241 0,07132247 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01082241 0,07111869 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01082241 0,07091607 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01082241 0,0707146 ! neural plate development GO:0001840 6 5 0,000 0,01082241 0,07051428 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01082241 0,07031509 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01082241 0,07011702 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01082241 0,06992006 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01082241 0,0697242 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01082241 0,06952944 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01082241 0,06933577 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01082241 0,06914317 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01082241 0,06895164 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01082241 0,06876116 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01082241 0,06857174 ! spindle assembly GO:0051225 5 5 0,000 0,01082241 0,06838335 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01082241 0,068196 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01082241 0,06800967 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01082241 0,06782436 ! organ regeneration GO:0031100 7 5 0,000 0,01082241 0,06764006 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01082241 0,06745675 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01082241 0,06727443 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01082241 0,0670931 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01082241 0,06691274 GO:0055081|anion homeostasis, ! response to oxygen levels GO:0070482 137 74 1,000 0,01126134 0,06943991 ! protein import into nucleus GO:0006606 118 74 1,000 0,01126134 0,06925424 ! response to inorganic substance GO:0010035 115 75 1,000 0,01155414 0,07086537 ! negative regulation of growth GO:0045926 123 75 1,000 0,01155414 0,0706769 ! nuclear import GO:0051170 121 75 1,000 0,01155414 0,07048943 ! regulation of protein transport GO:0051223 114 76 1,000 0,01185027 0,07210485 GO:0070201|regulation of establishment of protein localization, ! sex differentiation GO:0007548 105 77 1,000 0,01214974 0,07373194 ! protein ubiquitination GO:0016567 125 77 1,000 0,01214974 0,0735379 ! tRNA transcription GO:0009304 11 6 0,000 0,01297316 0,07831569 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01297316 0,07811067 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01297316 0,07790673 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01297316 0,07770385 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01297316 0,07750202 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01297316 0,07730124 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01297316 0,07710149 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01297316 0,07690278 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01297316 0,07670508 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01297316 0,0765084 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01297316 0,07631273 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01297316 0,07611805 ! prostate gland development GO:0030850 9 6 0,000 0,01297316 0,07592437 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01297316 0,07573167 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01297316 0,07553994 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01297316 0,07534919 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01297316 0,07515939 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01297316 0,07497055 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01297316 0,07478265 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01297316 0,07459569 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01297316 0,07440967 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01297316 0,07422457 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01297316 0,07404039 ! neuron adhesion GO:0007158 9 6 0,000 0,01297316 0,07385712 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01297316 0,07367476 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01297316 0,07349329 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01297316 0,07331272 ! signal peptide processing GO:0006465 8 6 0,000 0,01297316 0,07313303 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01297316 0,07295422 ! mRNA stabilization GO:0048255 15 6 0,000 0,01297316 0,07277629 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01297316 0,07259922 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01297316 0,072423 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01297316 0,07224765 ! opsonization GO:0008228 8 6 0,000 0,01297316 0,07207313 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01297316 0,07189946 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01297316 0,07172663 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01297316 0,07155462 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01297316 0,07138344 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01297316 0,07121307 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01297316 0,07104352 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01297316 0,07087477 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01297316 0,07070682 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01297316 0,07053966 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01297316 0,0703733 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01297316 0,07020771 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01297316 0,0700429 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01297316 0,06987887 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01297316 0,0697156 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01297316 0,06955309 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01297316 0,06939134 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01297316 0,06923034 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01297316 0,06907009 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01297316 0,06891057 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01297316 0,06875179 ! thymic T cell selection GO:0045061 12 6 0,000 0,01297316 0,06859374 ! protein lipoylation GO:0009249 10 6 0,000 0,01297316 0,06843642 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01297316 0,06827981 ! pigment granule organization GO:0048753 11 6 0,000 0,01297316 0,06812392 ! drug transport GO:0015893 6 6 0,000 0,01297316 0,06796874 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01297316 0,06781427 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01297316 0,06766049 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01297316 0,06750742 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01297316 0,06735503 ! histidine metabolic process GO:0006547 6 6 0,000 0,01297316 0,06720333 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01297316 0,06705231 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01297316 0,06690197 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,01297316 0,0667523 ! adenohypophysis development GO:0021984 10 6 0,000 0,01297316 0,0666033 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01297316 0,06645496 ! microtubule nucleation GO:0007020 10 6 0,000 0,01297316 0,06630728 ! ER overload response GO:0006983 7 6 0,000 0,01297316 0,06616026 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01297316 0,06601389 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01297316 0,06586816 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01297316 0,06572308 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01297316 0,06557863 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01297316 0,06543482 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01297316 0,06529164 ! response to dietary excess GO:0002021 7 6 0,000 0,01297316 0,06514908 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01297316 0,06500714 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01297316 0,06486582 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01297316 0,06472511 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01297316 0,06458502 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01297316 0,06444552 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01297316 0,06430663 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01297316 0,06416834 ! neuron apoptosis GO:0051402 8 6 0,000 0,01297316 0,06403064 ! organic alcohol transport GO:0015850 9 6 0,000 0,01297316 0,06389353 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01297316 0,063757 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01297316 0,06362106 ! carnitine transport GO:0015879 8 6 0,000 0,01297316 0,0634857 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01297316 0,06335091 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01297316 0,06321669 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01297316 0,06308304 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01297316 0,06294995 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01297316 0,06281743 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01297316 0,06268546 ! parturition GO:0007567 12 6 0,000 0,01297316 0,06255404 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01297316 0,06242317 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01297316 0,06229285 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01297316 0,06216308 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01297316 0,06203384 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01297316 0,06190514 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01297316 0,06177697 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01297316 0,06164933 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01297316 0,06152222 ! macrophage differentiation GO:0030225 10 6 0,000 0,01297316 0,06139563 ! astrocyte development GO:0014002 14 6 0,000 0,01297316 0,06126956 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01297316 0,06114401 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01297316 0,06101897 ! interaction with symbiont GO:0051702 8 6 0,000 0,01297316 0,06089444 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01297316 0,06077042 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01297316 0,06064691 ! eating behavior GO:0042755 6 6 0,000 0,01297316 0,06052389 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01297316 0,06040137 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01297316 0,06027935 ! response to copper ion GO:0046688 9 6 0,000 0,01297316 0,06015782 ! DNA topological change GO:0006265 8 6 0,000 0,01297316 0,06003678 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01297316 0,05991622 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01297316 0,05979615 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01297316 0,05967655 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01297316 0,05955744 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01297316 0,0594388 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01297316 0,05932063 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01297316 0,05920293 ! gas homeostasis GO:0033483 11 6 0,000 0,01297316 0,0590857 ! hair follicle maturation GO:0048820 7 6 0,000 0,01297316 0,05896893 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01297316 0,05885262 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01297316 0,05873677 ! Schwann cell development GO:0014044 14 6 0,000 0,01297316 0,05862137 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01297316 0,05850643 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01297316 0,05839193 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01297316 0,05827789 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01297316 0,05816428 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01297316 0,05805112 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01297316 0,0579384 ! histone ubiquitination GO:0016574 7 6 0,000 0,01297316 0,05782612 ! regulation of meiosis GO:0040020 10 6 0,000 0,01297316 0,05771427 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01297316 0,05760285 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01297316 0,05749186 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01297316 0,0573813 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01297316 0,05727117 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01297316 0,05716145 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01297316 0,05705216 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01297316 0,05694328 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01297316 0,05683481 ! receptor internalization GO:0031623 9 6 0,000 0,01297316 0,05672676 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01297316 0,05661912 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01297316 0,05651189 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01297316 0,05640506 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01297316 0,05629864 ! protein deubiquitination GO:0016579 8 6 0,000 0,01297316 0,05619261 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01297316 0,05608699 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01297316 0,05598176 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01297316 0,05587692 ! axonal fasciculation GO:0007413 9 6 0,000 0,01297316 0,05577248 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01297316 0,05566843 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01297316 0,05556476 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01297316 0,05546148 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01297316 0,05535859 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01297316 0,05525607 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01297316 0,05515393 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01297316 0,05505217 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01297316 0,05495079 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01297316 0,05484977 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01297316 0,05474913 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01297316 0,05464886 ! adult feeding behavior GO:0008343 6 6 0,000 0,01297316 0,05454895 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01297316 0,05444941 ! blastocyst growth GO:0001832 15 6 0,000 0,01297316 0,05435023 ! pigment granule transport GO:0051904 12 6 0,000 0,01297316 0,05425141 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01297316 0,05415295 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01297316 0,05405485 ! catecholamine transport GO:0051937 7 6 0,000 0,01297316 0,0539571 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01297316 0,05385971 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01297316 0,05376266 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01297316 0,05366597 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01297316 0,05356962 ! protein prenylation GO:0018342 10 6 0,000 0,01297316 0,05347362 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01297316 0,05337796 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01297316 0,05328264 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01297316 0,05318766 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01297316 0,05309302 ! protein localization in nucleus GO:0034504 133 80 1,000 0,01306796 0,05338596 ! detection of stimulus GO:0051606 108 82 1,000 0,01369646 0,05585437 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,01466347 0,05969201 ! regulation of protein localization GO:0032880 132 85 1,000 0,01466347 0,05958655 ! cell cycle arrest GO:0007050 150 86 1,000 0,01499222 0,06081499 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01511937 0,06122278 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01511937 0,06111519 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01511937 0,06100797 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01511937 0,06090112 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01511937 0,06079465 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01511937 0,06068855 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01511937 0,06058282 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01511937 0,06047746 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01511937 0,06037247 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01511937 0,06026784 ! reproductive behavior GO:0019098 12 7 0,000 0,01511937 0,06016357 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01511937 0,06005966 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01511937 0,05995611 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01511937 0,05985291 ! oligopeptide transport GO:0006857 11 7 0,000 0,01511937 0,05975007 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01511937 0,05964758 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01511937 0,05954545 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,01511937 0,05944366 ! RNA methylation GO:0001510 11 7 0,000 0,01511937 0,05934222 ! pericardium development GO:0060039 8 7 0,000 0,01511937 0,05924113 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01511937 0,05914038 ! fibril organization GO:0043206 13 7 0,000 0,01511937 0,05903997 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01511937 0,0589399 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01511937 0,05884017 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01511937 0,05874078 ! lipoprotein transport GO:0042953 9 7 0,000 0,01511937 0,05864172 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01511937 0,058543 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01511937 0,05844461 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01511937 0,05834655 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01511937 0,05824881 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01511937 0,05815141 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01511937 0,05805433 ! chemosensory behavior GO:0007635 9 7 0,000 0,01511937 0,05795757 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01511937 0,05786113 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01511937 0,05776502 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01511937 0,05766922 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01511937 0,05757374 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01511937 0,05747858 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01511937 0,05738373 ! reflex GO:0060004 12 7 0,000 0,01511937 0,05728919 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01511937 0,05719497 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01511937 0,05710105 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01511937 0,05700744 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01511937 0,05691414 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01511937 0,05682115 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01511937 0,05672845 ! spinal cord patterning GO:0021511 7 7 0,000 0,01511937 0,05663606 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01511937 0,05654397 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01511937 0,05645218 ! adrenal gland development GO:0030325 17 7 0,000 0,01511937 0,05636068 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01511937 0,05626948 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01511937 0,05617858 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01511937 0,05608797 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01511937 0,05599765 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01511937 0,05590762 ! endosome organization GO:0007032 10 7 0,000 0,01511937 0,05581788 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01511937 0,05572843 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01511937 0,05563927 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01511937 0,05555039 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01511937 0,05546179 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01511937 0,05537347 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01511937 0,05528544 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01511937 0,05519768 ! galactose metabolic process GO:0006012 10 7 0,000 0,01511937 0,05511021 ! vesicle fusion GO:0006906 15 7 0,000 0,01511937 0,05502301 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01511937 0,05493608 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01511937 0,05484943 ! organ growth GO:0035265 11 7 0,000 0,01511937 0,05476306 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01511937 0,05467695 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01511937 0,05459112 ! retinol metabolic process GO:0042572 9 7 0,000 0,01511937 0,05450555 ! behavioral fear response GO:0001662 13 7 0,000 0,01511937 0,05442025 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01511937 0,05433522 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01511937 0,05425045 ! rRNA modification GO:0000154 12 7 0,000 0,01511937 0,05416595 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01511937 0,05408171 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01511937 0,05399773 ! response to UV-B GO:0010224 11 7 0,000 0,01511937 0,05391402 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01511937 0,05383056 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01511937 0,05374736 ! intermediate filament organization GO:0045109 11 7 0,000 0,01511937 0,05366442 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01511937 0,05358173 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01511937 0,05349929 ! fibrinolysis GO:0042730 9 7 0,000 0,01511937 0,05341711 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01511937 0,05333519 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01511937 0,05325351 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01511937 0,05317208 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01511937 0,0530909 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01511937 0,05300997 ! response to tropane GO:0014073 13 7 0,000 0,01511937 0,05292929 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01511937 0,05284885 ! melanosome localization GO:0032400 10 7 0,000 0,01511937 0,05276865 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01511937 0,0526887 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01511937 0,05260899 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01511937 0,05252952 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01511937 0,05245029 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01511937 0,0523713 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01511937 0,05229254 ! mast cell activation GO:0045576 9 7 0,000 0,01511937 0,05221403 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01511937 0,05213574 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01511937 0,0520577 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01511937 0,05197988 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01511937 0,0519023 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01511937 0,05182495 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01511937 0,05174783 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01511937 0,05167094 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01511937 0,05159427 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01511937 0,05151784 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01511937 0,05144163 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01511937 0,05136564 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01511937 0,05128988 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01511937 0,05121435 ! response to tumor cell GO:0002347 12 7 0,000 0,01511937 0,05113903 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01511937 0,05106394 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01511937 0,05098906 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01511937 0,05091441 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01511937 0,05083997 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01511937 0,05076575 ! diuresis GO:0030146 12 7 0,000 0,01511937 0,05069175 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01511937 0,05061796 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01511937 0,05054439 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01511937 0,05047103 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01511937 0,05039789 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01511937 0,05032495 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01511937 0,05025223 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01511937 0,05017971 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01511937 0,05010741 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01511937 0,05003531 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01511937 0,04996342 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01511937 0,04989174 ! lymph node development GO:0048535 9 7 0,000 0,01511937 0,04982026 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01511937 0,04974899 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01511937 0,04967792 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01511937 0,04960705 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01511937 0,04953638 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01511937 0,04946592 ! ATP catabolic process GO:0006200 10 7 0,000 0,01511937 0,04939566 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01511937 0,04932559 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01511937 0,04925572 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01511937 0,04918606 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01511937 0,04911658 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01511937 0,04904731 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01511937 0,04897823 ! muscle adaptation GO:0043500 12 7 0,000 0,01511937 0,04890934 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01511937 0,04884065 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01511937 0,04877215 ! retina homeostasis GO:0001895 9 7 0,000 0,01511937 0,04870384 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01511937 0,04863572 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01511937 0,0485678 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01511937 0,04850006 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01511937 0,04843251 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01511937 0,04836515 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01511937 0,04829797 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01511937 0,04823099 ! reproductive developmental process GO:0003006 127 89 1,000 0,01599747 0,05096146 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,01633884 0,05197695 ! response to virus GO:0009615 122 91 1,000 0,01668334 0,05299955 ! cell fate commitment GO:0045165 141 92 1,000 0,01703094 0,05402918 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01726102 0,05468368 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01726102 0,05460846 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,01726102 0,05453345 ! axon extension GO:0048675 11 8 0,000 0,01726102 0,05445865 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01726102 0,05438405 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01726102 0,05430965 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01726102 0,05423546 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01726102 0,05416146 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01726102 0,05408767 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01726102 0,05401409 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,01726102 0,0539407 ! phosphate transport GO:0006817 10 8 0,000 0,01726102 0,05386751 ! N-glycan processing GO:0006491 12 8 0,000 0,01726102 0,05379452 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01726102 0,05372172 ! UTP metabolic process GO:0046051 8 8 0,000 0,01726102 0,05364913 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01726102 0,05357673 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01726102 0,05350452 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01726102 0,05343251 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01726102 0,05336069 ! succinate metabolic process GO:0006105 14 8 0,000 0,01726102 0,05328906 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,01726102 0,05321763 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01726102 0,05314639 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01726102 0,05307534 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01726102 0,05300448 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01726102 0,0529338 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01726102 0,05286332 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01726102 0,05279302 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01726102 0,05272291 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01726102 0,05265299 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01726102 0,05258325 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01726102 0,05251369 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01726102 0,05244432 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01726102 0,05237514 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01726102 0,05230613 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01726102 0,05223731 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01726102 0,05216866 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01726102 0,0521002 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01726102 0,05203192 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01726102 0,05196381 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01726102 0,05189589 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01726102 0,05182814 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01726102 0,05176057 ! melanin metabolic process GO:0006582 12 8 0,000 0,01726102 0,05169317 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01726102 0,05162595 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01726102 0,0515589 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01726102 0,05149203 ! macrophage activation GO:0042116 12 8 0,000 0,01726102 0,05142533 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01726102 0,0513588 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01726102 0,05129245 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01726102 0,05122626 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01726102 0,05116025 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01726102 0,05109441 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01726102 0,05102873 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01726102 0,05096323 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01726102 0,05089789 ! ruffle organization GO:0031529 11 8 0,000 0,01726102 0,05083272 ! osteoblast development GO:0002076 13 8 0,000 0,01726102 0,05076772 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01726102 0,05070288 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01726102 0,05063821 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01726102 0,0505737 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01726102 0,05050936 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01726102 0,05044518 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01726102 0,05038116 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01726102 0,0503173 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01726102 0,05025361 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01726102 0,05019008 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01726102 0,05012671 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01726102 0,0500635 ! segment specification GO:0007379 10 8 0,000 0,01726102 0,05000045 ! cellular extravasation GO:0045123 11 8 0,000 0,01726102 0,04993755 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01726102 0,04987482 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01726102 0,04981224 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01726102 0,04974982 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01726102 0,04968755 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01726102 0,04962544 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01726102 0,04956349 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01726102 0,04950169 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01726102 0,04944004 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01726102 0,04937855 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01726102 0,04931721 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01726102 0,04925602 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01726102 0,04919499 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01726102 0,0491341 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01726102 0,04907337 ! icosanoid secretion GO:0032309 12 8 0,000 0,01726102 0,04901278 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01726102 0,04895235 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01726102 0,04889206 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01726102 0,04883192 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01726102 0,04877193 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01726102 0,04871209 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01726102 0,04865239 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01726102 0,04859284 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01726102 0,04853344 ! sterol catabolic process GO:0016127 9 8 0,000 0,01726102 0,04847418 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01726102 0,04841507 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01726102 0,04835609 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01726102 0,04829727 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01726102 0,04823858 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01726102 0,04818004 ! prophase GO:0051324 11 8 0,000 0,01726102 0,04812164 ! S phase GO:0051320 8 8 0,000 0,01726102 0,04806338 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01726102 0,04800526 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01726102 0,04794729 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01726102 0,04788945 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01726102 0,04783175 ! hormone catabolic process GO:0042447 13 8 0,000 0,01726102 0,04777419 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01726102 0,04771677 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01726102 0,04765949 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01726102 0,04760234 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01726102 0,04754533 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01726102 0,04748846 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01726102 0,04743172 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01726102 0,04737512 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01726102 0,04731866 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01726102 0,04726233 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01726102 0,04720613 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01726102 0,04715006 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01726102 0,04709413 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01726102 0,04703833 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01726102 0,04698267 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01726102 0,04692713 ! response to oxidative stress GO:0006979 141 94 1,000 0,0177354 0,04815989 ! angiogenesis GO:0001525 149 95 1,000 0,01809224 0,04907093 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,01845212 0,04998809 ! response to light stimulus GO:0009416 153 96 1,000 0,01845212 0,04992928 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01939815 0,05242742 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01939815 0,05236589 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01939815 0,0523045 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01939815 0,05224325 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,01939815 0,05218215 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01939815 0,05212119 GO:0006740|NADPH regeneration, ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01939815 0,05206037 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01939815 0,05199969 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01939815 0,05193916 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01939815 0,05187876 ! GTP metabolic process GO:0046039 9 9 0,000 0,01939815 0,05181851 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01939815 0,05175839 ! social behavior GO:0035176 14 9 0,000 0,01939815 0,05169842 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01939815 0,05163858 ! artery development GO:0060840 19 9 0,000 0,01939815 0,05157888 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01939815 0,05151933 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01939815 0,0514599 ! response to pain GO:0048265 16 9 0,000 0,01939815 0,05140062 ! protein complex disassembly GO:0043241 17 9 0,000 0,01939815 0,05134147 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01939815 0,05128245 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01939815 0,05122358 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01939815 0,05116483 ! lung alveolus development GO:0048286 17 9 0,000 0,01939815 0,05110623 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01939815 0,05104775 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01939815 0,05098941 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01939815 0,0509312 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01939815 0,05087313 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01939815 0,05081519 ! protein targeting to ER GO:0045047 19 9 0,000 0,01939815 0,05075738 ! T cell selection GO:0045058 18 9 0,000 0,01939815 0,0506997 ! endoderm development GO:0007492 12 9 0,000 0,01939815 0,05064215 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01939815 0,05058473 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01939815 0,05052745 ! arginine catabolic process GO:0006527 10 9 0,000 0,01939815 0,05047029 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01939815 0,05041326 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01939815 0,05035636 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01939815 0,05029959 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01939815 0,05024295 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01939815 0,05018643 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01939815 0,05013004 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01939815 0,05007378 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01939815 0,05001764 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01939815 0,04996163 ! mannose metabolic process GO:0006013 9 9 0,000 0,01939815 0,04990574 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01939815 0,04984998 ! receptor clustering GO:0043113 15 9 0,000 0,01939815 0,04979435 ! epithelial cell development GO:0002064 10 9 0,000 0,01939815 0,04973884 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01939815 0,04968345 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01939815 0,04962818 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01939815 0,04957304 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01939815 0,04951802 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01939815 0,04946312 ! motor axon guidance GO:0008045 14 9 0,000 0,01939815 0,04940834 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01939815 0,04935369 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01939815 0,04929916 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01939815 0,04924474 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01939815 0,04919045 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01939815 0,04913627 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01939815 0,04908222 ! DNA ligation GO:0006266 14 9 0,000 0,01939815 0,04902828 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01939815 0,04897446 ! response to amine stimulus GO:0014075 13 9 0,000 0,01939815 0,04892076 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01939815 0,04886718 ! erythrocyte development GO:0048821 11 9 0,000 0,01939815 0,04881371 ! renal water homeostasis GO:0003091 14 9 0,000 0,01939815 0,04876037 ! postreplication repair GO:0006301 11 9 0,000 0,01939815 0,04870713 ! mRNA cleavage GO:0006379 13 9 0,000 0,01939815 0,04865402 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01939815 0,04860102 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01939815 0,04854813 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01939815 0,04849536 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01939815 0,04844271 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01939815 0,04839017 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01939815 0,04833774 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01939815 0,04828543 ! acid secretion GO:0046717 14 9 0,000 0,01939815 0,04823323 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01939815 0,04818114 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01939815 0,04812916 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01939815 0,0480773 ! purine base metabolic process GO:0006144 18 9 0,000 0,01939815 0,04802555 ! oocyte differentiation GO:0009994 12 9 0,000 0,01939815 0,04797391 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01939815 0,04792238 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01939815 0,04787096 ! spleen development GO:0048536 15 9 0,000 0,01939815 0,04781965 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01939815 0,04776845 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01939815 0,04771736 ! detection of calcium ion GO:0005513 13 9 0,000 0,01939815 0,04766638 ! blastocyst formation GO:0001825 12 9 0,000 0,01939815 0,04761551 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01939815 0,04756475 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01939815 0,0475141 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01939815 0,04746355 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01939815 0,04741311 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01939815 0,04736278 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01939815 0,04731255 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01939815 0,04726243 ! prepulse inhibition GO:0060134 14 9 0,000 0,01939815 0,04721242 ! embryonic placenta development GO:0001892 12 9 0,000 0,01939815 0,04716251 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,01939815 0,04711271 ! insulin secretion GO:0030073 17 9 0,000 0,01939815 0,04706301 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01939815 0,04701342 ! response to nicotine GO:0035094 16 9 0,000 0,01939815 0,04696393 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01939815 0,04691455 ! nucleus localization GO:0051647 15 9 0,000 0,01939815 0,04686527 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01939815 0,04681609 ! protein import GO:0017038 156 99 1,000 0,01954993 0,04713296 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,01992187 0,04797938 ! protein localization in organelle GO:0033365 161 100 1,000 0,01992187 0,0479292 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02153074 0,05174578 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02153074 0,05169176 ! neuron fate specification GO:0048665 11 10 0,000 0,02153074 0,05163786 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02153074 0,05158407 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02153074 0,05153039 ! thyroid gland development GO:0030878 19 10 0,000 0,02153074 0,05147683 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,02153074 0,05142337 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02153074 0,05137003 ! synapsis GO:0007129 13 10 0,000 0,02153074 0,0513168 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02153074 0,05126367 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02153074 0,05121066 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02153074 0,05115776 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02153074 0,05110496 ! sulfate transport GO:0008272 12 10 0,000 0,02153074 0,05105228 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02153074 0,0509997 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02153074 0,05094723 ! androgen metabolic process GO:0008209 13 10 0,000 0,02153074 0,05089487 ! phospholipid efflux GO:0033700 16 10 0,000 0,02153074 0,05084262 ! hippocampus development GO:0021766 19 10 0,000 0,02153074 0,05079047 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02153074 0,05073843 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02153074 0,0506865 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02153074 0,05063467 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02153074 0,05058295 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02153074 0,05053134 ! pathogenesis GO:0009405 13 10 0,000 0,02153074 0,05047983 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02153074 0,05042842 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02153074 0,05037712 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02153074 0,05032592 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02153074 0,05027483 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02153074 0,05022384 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02153074 0,05017296 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02153074 0,05012218 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02153074 0,0500715 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02153074 0,05002092 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02153074 0,04997044 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02153074 0,04992007 ! response to X-ray GO:0010165 16 10 0,000 0,02153074 0,0498698 ! B cell proliferation GO:0042100 14 10 0,000 0,02153074 0,04981963 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02153074 0,04976956 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02153074 0,04971959 ! forebrain cell migration GO:0021885 17 10 0,000 0,02153074 0,04966972 ! lipid digestion GO:0044241 15 10 0,000 0,02153074 0,04961995 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02153074 0,04957028 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02153074 0,04952071 ! UV protection GO:0009650 14 10 0,000 0,02153074 0,04947124 ! entry into host cell GO:0030260 20 10 0,000 0,02153074 0,04942187 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02153074 0,04937259 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02153074 0,04932342 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02153074 0,04927434 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02153074 0,04922536 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02153074 0,04917647 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02153074 0,04912769 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02153074 0,049079 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02153074 0,0490304 ! regulation of organ growth GO:0046620 11 10 0,000 0,02153074 0,04898191 ! response to dsRNA GO:0043331 18 10 0,000 0,02153074 0,04893351 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02153074 0,0488852 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02153074 0,04883699 ! embryonic axis specification GO:0000578 12 10 0,000 0,02153074 0,04878888 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02153074 0,04874086 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02153074 0,04869293 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02153074 0,0486451 ! cranial nerve development GO:0021545 12 10 0,000 0,02153074 0,04859736 ! fucose catabolic process GO:0019317 16 10 0,000 0,02153074 0,04854971 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02153074 0,04850216 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02153074 0,04845471 ! protein sumoylation GO:0016925 12 10 0,000 0,02153074 0,04840734 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02153074 0,04836007 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02153074 0,04831289 ! zymogen activation GO:0031638 14 10 0,000 0,02153074 0,0482658 ! salivary gland development GO:0007431 22 10 0,000 0,02153074 0,0482188 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02153074 0,0481719 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02153074 0,04812508 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02153074 0,04807836 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02153074 0,04803173 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02153074 0,04798518 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02153074 0,04793873 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02153074 0,04789237 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02153074 0,0478461 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02153074 0,04779991 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02153074 0,04775382 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02153074 0,04770781 ! detection of bacterium GO:0016045 10 10 0,000 0,02153074 0,0476619 ! activation of innate immune response GO:0002218 10 10 0,000 0,02153074 0,04761607 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02153074 0,04757033 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02153074 0,04752467 ! developmental induction GO:0031128 13 10 0,000 0,02153074 0,04747911 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02153074 0,04743363 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02153074 0,04738824 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02153074 0,04734293 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02153074 0,04729772 ! rRNA transcription GO:0009303 17 11 0,000 0,02365882 0,05192299 ! respiratory burst GO:0045730 14 11 0,000 0,02365882 0,05187349 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02365882 0,05182409 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02365882 0,05177478 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02365882 0,05172557 ! virus-host interaction GO:0019048 17 11 0,000 0,02365882 0,05167644 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02365882 0,05162741 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02365882 0,05157848 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02365882 0,05152964 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02365882 0,05148088 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02365882 0,05143223 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,02365882 0,05138366 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02365882 0,05133518 ! T cell proliferation GO:0042098 20 11 0,000 0,02365882 0,0512868 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02365882 0,05123851 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02365882 0,05119031 ! bone resorption GO:0045453 16 11 0,000 0,02365882 0,05114219 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02365882 0,05109417 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02365882 0,05104624 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02365882 0,0509984 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02365882 0,05095065 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02365882 0,05090299 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02365882 0,05085542 ! syncytium formation GO:0006949 15 11 0,000 0,02365882 0,05080793 ! plasma membrane organization GO:0007009 18 11 0,000 0,02365882 0,05076054 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02365882 0,05071323 ! focal adhesion formation GO:0048041 24 11 0,000 0,02365882 0,05066601 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02365882 0,05061888 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02365882 0,05057184 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02365882 0,05052488 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02365882 0,05047801 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02365882 0,05043123 ! adult heart development GO:0007512 11 11 0,000 0,02365882 0,05038453 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02365882 0,05033792 ! temperature homeostasis GO:0001659 16 11 0,000 0,02365882 0,0502914 ! L-glutamate transport GO:0015813 16 11 0,000 0,02365882 0,05024496 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02365882 0,05019861 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02365882 0,05015235 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02365882 0,05010617 ! stem cell development GO:0048864 29 11 0,000 0,02365882 0,05006007 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02365882 0,05001406 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02365882 0,04996813 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02365882 0,04992229 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02365882 0,04987653 ! vasoconstriction GO:0042310 15 11 0,000 0,02365882 0,04983086 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02365882 0,04978527 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02365882 0,04973976 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02365882 0,04969433 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02365882 0,04964899 ! ribosome assembly GO:0042255 13 11 0,000 0,02365882 0,04960373 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02365882 0,04955856 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02365882 0,04951346 ! chromatin silencing GO:0006342 19 11 0,000 0,02365882 0,04946845 ! nucleosome positioning GO:0016584 13 11 0,000 0,02365882 0,04942352 ! T cell homeostasis GO:0043029 20 11 0,000 0,02365882 0,04937867 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02365882 0,0493339 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02365882 0,04928922 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02365882 0,04924461 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02365882 0,04920009 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02365882 0,04915564 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02365882 0,04911128 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02365882 0,04906699 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02365882 0,04902279 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02365882 0,04897866 ! male genitalia development GO:0030539 13 11 0,000 0,02365882 0,04893462 ! cholesterol efflux GO:0033344 19 11 0,000 0,02365882 0,04889065 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02365882 0,04884676 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02365882 0,04880296 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02365882 0,04875923 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02365882 0,04871557 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02365882 0,048672 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02365882 0,0486285 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02365882 0,04858509 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02365882 0,04854174 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02365882 0,04849848 ! lysogeny GO:0030069 18 11 0,000 0,02365882 0,04845529 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02365882 0,04841218 ! acrosome reaction GO:0007340 13 11 0,000 0,02365882 0,04836915 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02365882 0,04832619 ! lactation GO:0007595 20 12 0,000 0,0257824 0,05261714 ! reproductive cellular process GO:0048610 14 12 0,000 0,0257824 0,05257049 ! tRNA modification GO:0006400 14 12 0,000 0,0257824 0,05252393 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,0257824 0,05247745 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,0257824 0,05243105 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,0257824 0,05238473 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,0257824 0,0523385 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,0257824 0,05229234 ! non-recombinational repair GO:0000726 19 12 0,000 0,0257824 0,05224627 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,0257824 0,05220028 ! peroxisomal transport GO:0043574 21 12 0,000 0,0257824 0,05215437 ! cartilage condensation GO:0001502 18 12 0,000 0,0257824 0,05210854 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,0257824 0,05206279 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,0257824 0,05201712 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,0257824 0,05197153 ! heart looping GO:0001947 15 12 0,000 0,0257824 0,05192602 ! palate development GO:0060021 15 12 0,000 0,0257824 0,05188059 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,0257824 0,05183524 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,0257824 0,05178997 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,0257824 0,05174478 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,0257824 0,05169967 ! arginine metabolic process GO:0006525 13 12 0,000 0,0257824 0,05165463 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,0257824 0,05160967 ! methionine metabolic process GO:0006555 13 12 0,000 0,0257824 0,0515648 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,0257824 0,05152 ! Golgi organization GO:0007030 18 12 0,000 0,0257824 0,05147527 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,0257824 0,05143063 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,0257824 0,05138606 ! monoamine transport GO:0015844 13 12 0,000 0,0257824 0,05134157 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0257824 0,05129716 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,0257824 0,05125282 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,0257824 0,05120856 ! L-amino acid transport GO:0015807 20 12 0,000 0,0257824 0,05116438 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,0257824 0,05112027 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,0257824 0,05107624 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,0257824 0,05103229 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0257824 0,05098841 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,0257824 0,0509446 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,0257824 0,05090087 ! cerebellum development GO:0021549 13 12 0,000 0,0257824 0,05085722 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,0257824 0,05081364 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,0257824 0,05077013 ! histone acetylation GO:0016573 23 12 0,000 0,0257824 0,0507267 ! histone methylation GO:0016571 15 12 0,000 0,0257824 0,05068335 ! autonomic nervous system development GO:0048483 23 12 0,000 0,0257824 0,05064006 ! gland morphogenesis GO:0022612 23 12 0,000 0,0257824 0,05059686 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,0257824 0,05055372 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,0257824 0,05051066 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,0257824 0,05046767 ! response to gamma radiation GO:0010332 20 12 0,000 0,0257824 0,05042476 ! regulation of epidermis development GO:0045682 17 12 0,000 0,0257824 0,05038192 ! intestinal absorption GO:0050892 19 12 0,000 0,0257824 0,05033915 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,0257824 0,05029645 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,0257824 0,05025383 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,0257824 0,05021128 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,0257824 0,0501688 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,0257824 0,05012639 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,0257824 0,05008405 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,0257824 0,05004179 ! microspike assembly GO:0030035 23 12 0,000 0,0257824 0,04999959 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,0257824 0,04995747 ! response to cold GO:0009409 14 12 0,000 0,0257824 0,04991542 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,02790147 0,05397258 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,02790147 0,05392722 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02790147 0,05388194 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02790147 0,05383674 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02790147 0,05379161 ! water transport GO:0006833 17 13 0,000 0,02790147 0,05374656 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02790147 0,05370158 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02790147 0,05365668 ! lipid localization GO:0010876 24 13 0,000 0,02790147 0,05361186 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02790147 0,05356711 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02790147 0,05352243 ! organelle fusion GO:0048284 28 13 0,000 0,02790147 0,05347783 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02790147 0,0534333 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02790147 0,05338885 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02790147 0,05334447 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02790147 0,05330016 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02790147 0,05325593 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02790147 0,05321177 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02790147 0,05316768 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02790147 0,05312367 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02790147 0,05307973 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02790147 0,05303586 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02790147 0,05299207 ! NAD metabolic process GO:0019674 21 13 0,000 0,02790147 0,05294834 ! exocrine system development GO:0035272 27 13 0,000 0,02790147 0,05290469 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02790147 0,05286111 ! bone mineralization GO:0030282 15 13 0,000 0,02790147 0,05281761 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02790147 0,05277417 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02790147 0,05273081 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02790147 0,05268751 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02790147 0,05264429 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02790147 0,05260114 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02790147 0,05255806 ! genitalia development GO:0048806 15 13 0,000 0,02790147 0,05251505 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02790147 0,05247211 ! cellular pigmentation GO:0033059 24 13 0,000 0,02790147 0,05242924 ! tissue regeneration GO:0042246 21 13 0,000 0,02790147 0,05238644 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02790147 0,05234371 ! cofactor transport GO:0051181 19 13 0,000 0,02790147 0,05230105 ! NADP metabolic process GO:0006739 18 13 0,000 0,02790147 0,05225846 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02790147 0,05221594 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02790147 0,05217349 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02790147 0,05213111 ! gas transport GO:0015669 18 13 0,000 0,02790147 0,05208879 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02790147 0,05204655 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02790147 0,05200437 ! regulation of axon extension GO:0030516 23 13 0,000 0,02790147 0,05196226 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02790147 0,05192022 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02790147 0,05187825 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02790147 0,05183634 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02790147 0,05179451 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02790147 0,05175274 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02790147 0,05171103 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,03001606 0,0555853 ! superoxide anion generation GO:0042554 18 14 0,000 0,03001606 0,05554058 ! neuron maturation GO:0042551 21 14 0,000 0,03001606 0,05549594 ! regulation of S phase GO:0033261 18 14 0,000 0,03001606 0,05545136 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,03001606 0,05540686 ! myotube differentiation GO:0014902 21 14 0,000 0,03001606 0,05536243 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,03001606 0,05531807 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,03001606 0,05527378 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,03001606 0,05522956 ! inositol metabolic process GO:0006020 20 14 0,000 0,03001606 0,05518541 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,03001606 0,05514133 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,03001606 0,05509732 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,03001606 0,05505339 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,03001606 0,05500952 ! gene silencing by RNA GO:0031047 20 14 0,000 0,03001606 0,05496572 ! response to cAMP GO:0051591 19 14 0,000 0,03001606 0,05492199 ! limbic system development GO:0021761 25 14 0,000 0,03001606 0,05487834 ! startle response GO:0001964 21 14 0,000 0,03001606 0,05483475 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,03001606 0,05479123 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,03001606 0,05474778 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,03001606 0,05470439 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,03001606 0,05466108 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,03001606 0,05461784 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,03001606 0,05457466 ! glycine metabolic process GO:0006544 22 14 0,000 0,03001606 0,05453155 ! pituitary gland development GO:0021983 23 14 0,000 0,03001606 0,05448851 ! cellular response to starvation GO:0009267 21 14 0,000 0,03001606 0,05444554 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,03001606 0,05440264 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,03001606 0,0543598 ! regulation of heart rate GO:0002027 23 14 0,000 0,03001606 0,05431703 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,03001606 0,05427433 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,03001606 0,05423169 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,03001606 0,05418913 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,03001606 0,05414662 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,03001606 0,05410419 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,03001606 0,05406182 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,03001606 0,05401952 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,03001606 0,05397728 ! axon cargo transport GO:0008088 27 14 0,000 0,03001606 0,05393511 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,03001606 0,05389301 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,03001606 0,05385097 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,03001606 0,053809 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,03001606 0,05376709 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03001606 0,05372525 ! mRNA splice site selection GO:0006376 26 14 0,000 0,03001606 0,05368347 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,03001606 0,05364176 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,03001606 0,05360011 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,03001606 0,05355853 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,03001606 0,05351701 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,03001606 0,05347556 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,03001606 0,05343417 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,03001606 0,05339284 ! muscle maintenance GO:0046716 19 14 0,000 0,03001606 0,05335158 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,03001606 0,05331038 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,03001606 0,05326925 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,03001606 0,05322818 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,03001606 0,05318717 ! cell killing GO:0001906 20 14 0,000 0,03001606 0,05314622 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,03001606 0,05310534 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,03001606 0,05306452 ! cilium assembly GO:0042384 20 14 0,000 0,03001606 0,05302377 ! peptide hormone secretion GO:0030072 23 14 0,000 0,03001606 0,05298307 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03212617 0,05666426 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03212617 0,05662084 ! metencephalon development GO:0022037 19 15 0,000 0,03212617 0,05657749 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03212617 0,0565342 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03212617 0,05649098 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03212617 0,05644782 ! skin development GO:0043588 25 15 0,000 0,03212617 0,05640473 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03212617 0,05636171 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03212617 0,05631875 ! lipid phosphorylation GO:0046834 23 15 0,000 0,03212617 0,05627585 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03212617 0,05623303 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03212617 0,05619026 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03212617 0,05614757 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03212617 0,05610493 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03212617 0,05606236 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03212617 0,05601986 ! adult walking behavior GO:0007628 25 15 0,000 0,03212617 0,05597742 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03212617 0,05593505 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03212617 0,05589274 ! myoblast differentiation GO:0045445 27 15 0,000 0,03212617 0,05585049 ! centrosome cycle GO:0007098 16 15 0,000 0,03212617 0,05580831 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03212617 0,05576619 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03212617 0,05572413 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03212617 0,05568214 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03212617 0,05564021 ! cerebral cortex development GO:0021987 29 15 0,000 0,03212617 0,05559834 ! vesicle coating GO:0006901 25 15 0,000 0,03212617 0,05555654 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03212617 0,0555148 ! DNA integration GO:0015074 22 15 0,000 0,03212617 0,05547312 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,03212617 0,05543151 ! peptide secretion GO:0002790 27 15 0,000 0,03212617 0,05538995 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03212617 0,05534846 ! regulation of vasodilation GO:0042312 24 15 0,000 0,03212617 0,05530703 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,03212617 0,05526567 ! neuron recognition GO:0008038 22 15 0,000 0,03212617 0,05522436 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03212617 0,05518312 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03212617 0,05514194 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,03212617 0,05510082 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03212617 0,05505976 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03212617 0,05501876 ! biomineral formation GO:0031214 18 15 0,000 0,03212617 0,05497783 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03212617 0,05493695 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03212617 0,05489613 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03212617 0,05485538 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03212617 0,05481469 ! organic cation transport GO:0015695 19 15 0,000 0,03212617 0,05477405 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03212617 0,05473348 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03212617 0,05469297 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03212617 0,05465251 ! defense response to virus GO:0051607 27 15 0,000 0,03212617 0,05461212 ! peptide hormone processing GO:0016486 19 15 0,000 0,03212617 0,05457179 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03212617 0,05453151 ! protein secretion GO:0009306 27 16 0,000 0,03423181 0,05806281 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03423181 0,05802002 ! hormone secretion GO:0046879 25 16 0,000 0,03423181 0,0579773 ! bone remodeling GO:0046849 24 16 0,000 0,03423181 0,05793463 ! endothelial cell migration GO:0043542 22 16 0,000 0,03423181 0,05789204 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03423181 0,0578495 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03423181 0,05780702 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03423181 0,05776461 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03423181 0,05772226 ! glial cell development GO:0021782 24 16 0,000 0,03423181 0,05767998 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03423181 0,05763775 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03423181 0,05759559 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03423181 0,05755349 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03423181 0,05751144 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03423181 0,05746947 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,03423181 0,05742755 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03423181 0,05738569 ! fructose metabolic process GO:0006000 20 16 0,000 0,03423181 0,05734389 ! regulation of protein binding GO:0043393 27 16 0,000 0,03423181 0,05730216 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,03423181 0,05726049 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03423181 0,05721887 ! protein export from nucleus GO:0006611 24 16 0,000 0,03423181 0,05717732 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03423181 0,05713583 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03423181 0,05709439 ! DNA replication initiation GO:0006270 25 16 0,000 0,03423181 0,05705302 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03423181 0,05701171 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03423181 0,05697045 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03423181 0,05692926 ! diencephalon development GO:0021536 25 16 0,000 0,03423181 0,05688813 ! oogenesis GO:0048477 23 16 0,000 0,03423181 0,05684705 ! neural crest cell migration GO:0001755 24 16 0,000 0,03423181 0,05680604 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03423181 0,05676508 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03423181 0,05672418 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03423181 0,05668335 ! steroid catabolic process GO:0006706 22 16 0,000 0,03423181 0,05664257 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03423181 0,05660185 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03423181 0,05656118 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03423181 0,05652058 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03423181 0,05648003 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03423181 0,05643955 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03423181 0,05639912 ! nerve development GO:0021675 18 16 0,000 0,03423181 0,05635875 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03423181 0,05631843 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,03423181 0,05627818 ! negative regulation of translation GO:0017148 22 16 0,000 0,03423181 0,05623798 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03633299 0,05964731 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03633299 0,05960476 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03633299 0,05956228 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03633299 0,05951986 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03633299 0,05947749 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03633299 0,05943519 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03633299 0,05939295 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03633299 0,05935077 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03633299 0,05930864 ! signal complex assembly GO:0007172 29 17 0,000 0,03633299 0,05926658 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03633299 0,05922458 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03633299 0,05918263 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03633299 0,05914075 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03633299 0,05909892 ! memory GO:0007613 25 17 0,000 0,03633299 0,05905716 ! keratinization GO:0031424 17 17 0,000 0,03633299 0,05901545 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03633299 0,0589738 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03633299 0,05893221 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03633299 0,05889068 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03633299 0,05884921 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,03633299 0,0588078 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03633299 0,05876644 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03633299 0,05872514 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03633299 0,0586839 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03633299 0,05864272 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03633299 0,0586016 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03633299 0,05856053 ! membrane budding GO:0006900 29 17 0,000 0,03633299 0,05851952 ! heme metabolic process GO:0042168 27 17 0,000 0,03633299 0,05847857 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03633299 0,05843768 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03633299 0,05839684 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03633299 0,05835606 ! body fluid secretion GO:0007589 27 17 0,000 0,03633299 0,05831534 ! stem cell differentiation GO:0048863 36 17 0,000 0,03633299 0,05827467 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03633299 0,05823406 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03633299 0,05819351 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03633299 0,05815301 ! sensory perception of pain GO:0019233 23 17 0,000 0,03633299 0,05811257 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03633299 0,05807219 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03633299 0,05803186 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03633299 0,05799159 ! synaptogenesis GO:0007416 24 17 0,000 0,03633299 0,05795137 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03633299 0,05791121 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03633299 0,05787111 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03633299 0,05783106 ! cell-cell junction organization GO:0045216 25 17 0,000 0,03633299 0,05779106 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03633299 0,05775113 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03633299 0,05771124 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03633299 0,05767141 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03633299 0,05763164 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03633299 0,05759192 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03633299 0,05755226 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03842972 0,06083163 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03842972 0,06078979 ! positive regulation of translation GO:0045727 28 18 0,000 0,03842972 0,06074801 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03842972 0,06070629 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03842972 0,06066462 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03842972 0,06062301 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03842972 0,06058146 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03842972 0,06053997 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03842972 0,06049853 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03842972 0,06045715 ! axis specification GO:0009798 26 18 0,000 0,03842972 0,06041583 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03842972 0,06037456 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03842972 0,06033335 ! pancreas development GO:0031016 26 18 0,000 0,03842972 0,06029219 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03842972 0,06025109 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03842972 0,06021005 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03842972 0,06016906 ! response to retinoic acid GO:0032526 25 18 0,000 0,03842972 0,06012813 ! pigmentation during development GO:0048066 31 18 0,000 0,03842972 0,06008726 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03842972 0,06004644 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,03842972 0,06000567 ! fucose metabolic process GO:0006004 26 18 0,000 0,03842972 0,05996496 ! response to fungus GO:0009620 19 18 0,000 0,03842972 0,05992431 ! peptide cross-linking GO:0018149 31 18 0,000 0,03842972 0,05988371 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03842972 0,05984316 ! heart process GO:0003015 27 18 0,000 0,03842972 0,05980267 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03842972 0,05976224 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03842972 0,05972186 ! visual learning GO:0008542 35 18 0,000 0,03842972 0,05968153 ! somitogenesis GO:0001756 24 18 0,000 0,03842972 0,05964126 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03842972 0,05960105 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03842972 0,05956088 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03842972 0,05952078 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03842972 0,05948072 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03842972 0,05944072 ! vitamin transport GO:0051180 24 18 0,000 0,03842972 0,05940077 ! hormone transport GO:0009914 27 18 0,000 0,03842972 0,05936088 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03842972 0,05932104 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03842972 0,05928126 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03842972 0,05924152 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03842972 0,05920184 ! cell-cell recognition GO:0009988 20 18 0,000 0,03842972 0,05916222 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03842972 0,05912264 ! regulation of glucose import GO:0046324 21 18 0,000 0,03842972 0,05908312 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03842972 0,05904366 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03842972 0,05900424 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03842972 0,05896488 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,040522 0,06213374 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,040522 0,06209234 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,040522 0,062051 ! positive regulation of ossification GO:0045778 30 19 0,000 0,040522 0,06200972 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,040522 0,06196849 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,040522 0,06192731 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,040522 0,06188619 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,040522 0,06184513 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,040522 0,06180412 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,040522 0,06176316 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,040522 0,06172226 ! regeneration GO:0031099 32 19 0,000 0,040522 0,06168141 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,040522 0,06164061 ! response to alkaloid GO:0043279 32 19 0,000 0,040522 0,06159987 ! sensory perception of taste GO:0050909 23 19 0,000 0,040522 0,06155919 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,040522 0,06151855 ! smooth muscle contraction GO:0006939 36 19 0,000 0,040522 0,06147797 ! peroxisome organization GO:0007031 29 19 0,000 0,040522 0,06143745 ! digestive system process GO:0022600 30 19 0,000 0,040522 0,06139698 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,040522 0,06135656 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,040522 0,06131619 ! response to vitamin A GO:0033189 26 19 0,000 0,040522 0,06127588 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,040522 0,06123562 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,040522 0,06119541 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,040522 0,06115526 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,040522 0,06111515 ! response to starvation GO:0042594 30 19 0,000 0,040522 0,0610751 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,040522 0,06103511 ! plasma membrane fusion GO:0045026 23 19 0,000 0,040522 0,06099516 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,040522 0,06095527 ! cytolysis GO:0019835 20 19 0,000 0,040522 0,06091543 ! renal system process GO:0003014 35 19 0,000 0,040522 0,06087564 ! vasodilation GO:0042311 33 19 0,000 0,040522 0,06083591 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,040522 0,06079622 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,040522 0,06075659 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,040522 0,06071701 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,040522 0,06067748 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,040522 0,060638 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,040522 0,06059858 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,040522 0,0605592 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,040522 0,06051988 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,040522 0,0604806 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,040522 0,06044138 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,040522 0,06040221 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,040522 0,06036309 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,040522 0,06032402 ! protein stabilization GO:0050821 26 19 0,000 0,040522 0,060285 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,04260986 0,06335014 ! iron ion transport GO:0006826 37 20 0,000 0,04260986 0,06330922 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,04260986 0,06326835 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,04260986 0,06322753 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,04260986 0,06318676 ! response to vitamin GO:0033273 29 20 0,000 0,04260986 0,06314605 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,04260986 0,06310539 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,04260986 0,06306478 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,04260986 0,06302422 ! spinal cord development GO:0021510 31 20 0,000 0,04260986 0,06298372 ! response to ethanol GO:0045471 37 20 0,000 0,04260986 0,06294327 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,04260986 0,06290287 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,04260986 0,06286252 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,04260986 0,06282222 ! chromosome condensation GO:0030261 31 20 0,000 0,04260986 0,06278198 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,04260986 0,06274179 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,04260986 0,06270164 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,04260986 0,06266155 ! pallium development GO:0021543 38 20 0,000 0,04260986 0,06262151 ! DNA modification GO:0006304 28 20 0,000 0,04260986 0,06258153 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,04260986 0,06254159 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,04260986 0,0625017 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,04260986 0,06246187 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,04260986 0,06242208 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,04260986 0,06238235 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,04260986 0,06234266 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,04260986 0,06230303 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,04260986 0,06226345 ! alditol metabolic process GO:0019400 24 20 0,000 0,04260986 0,06222392 ! actin filament-based movement GO:0030048 34 20 0,000 0,04260986 0,06218443 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04469328 0,06518361 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04469328 0,0651423 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04469328 0,06510105 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04469328 0,06505984 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,04469328 0,06501869 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04469328 0,06497759 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04469328 0,06493655 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04469328 0,06489555 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04469328 0,06485461 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04469328 0,06481372 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,04469328 0,06477288 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04469328 0,06473209 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04469328 0,06469135 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04469328 0,06465066 ! vesicle docking GO:0048278 27 21 0,000 0,04469328 0,06461003 ! phototransduction GO:0007602 25 21 0,000 0,04469328 0,06456944 ! dendrite development GO:0016358 35 21 0,000 0,04469328 0,06452891 ! visual behavior GO:0007632 39 21 0,000 0,04469328 0,06448843 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04469328 0,064448 ! ovarian follicle development GO:0001541 30 21 0,000 0,04469328 0,06440762 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04469328 0,06436729 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04469328 0,06432701 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04469328 0,06428678 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04469328 0,0642466 ! cell aging GO:0007569 32 21 0,000 0,04469328 0,06420647 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04469328 0,06416639 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,04469328 0,06412636 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,04469328 0,06408638 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04469328 0,06404645 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04469328 0,06400657 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04469328 0,06396674 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04469328 0,06392696 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04469328 0,06388723 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,04469328 0,06384755 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04469328 0,06380792 ! fatty acid transport GO:0015908 30 21 0,000 0,04469328 0,06376833 ! immunoglobulin production GO:0002377 33 21 0,000 0,04469328 0,0637288 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04469328 0,06368931 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04469328 0,06364988 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04469328 0,06361049 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,04469328 0,06357115 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04469328 0,06353186 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04469328 0,06349262 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04469328 0,06345343 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04469328 0,06341428 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04469328 0,06337519 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04469328 0,06333614 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04469328 0,06329714 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04469328 0,06325819 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04469328 0,06321928 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04469328 0,06318043 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,0467723 0,0660788 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,0467723 0,06603824 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,0467723 0,06599772 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,0467723 0,06595726 ! viral genome replication GO:0019079 29 22 0,000 0,0467723 0,06591684 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,0467723 0,06587648 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,0467723 0,06583616 ! leukocyte adhesion GO:0007159 38 22 0,000 0,0467723 0,06579589 ! molting cycle process GO:0022404 40 22 0,000 0,0467723 0,06575568 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,0467723 0,06571551 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,0467723 0,06567539 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,0467723 0,06563532 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,0467723 0,0655953 ! vasculogenesis GO:0001570 33 22 0,000 0,0467723 0,06555532 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,0467723 0,0655154 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,0467723 0,06547552 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,0467723 0,0654357 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,0467723 0,06539592 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,0467723 0,06535619 ! lysosome organization GO:0007040 37 22 0,000 0,0467723 0,06531651 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,0467723 0,06527687 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,0467723 0,06523729 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,0467723 0,06519775 ! regulation of behavior GO:0050795 38 22 0,000 0,0467723 0,06515826 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,0467723 0,06511882 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,0467723 0,06507942 ! membrane depolarization GO:0051899 35 22 0,000 0,0467723 0,06504008 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,0467723 0,06500078 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,0467723 0,06496152 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,0467723 0,06492232 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,0467723 0,06488316 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,0467723 0,06484405 ! blastocyst development GO:0001824 37 22 0,000 0,0467723 0,06480499 ! neural tube closure GO:0001843 33 22 0,000 0,0467723 0,06476598 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,0467723 0,06472701 ! protein tetramerization GO:0051262 39 22 0,000 0,0467723 0,06468808 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04884691 0,06751676 ! neuron fate commitment GO:0048663 32 23 0,000 0,04884691 0,06747621 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,04884691 0,0674357 ! myelination GO:0042552 35 23 0,000 0,04884691 0,06739525 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04884691 0,06735485 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04884691 0,06731449 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,04884691 0,06727418 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,04884691 0,06723392 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04884691 0,06719371 ! vesicle targeting GO:0006903 32 23 0,000 0,04884691 0,06715355 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04884691 0,06711343 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04884691 0,06707336 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04884691 0,06703334 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04884691 0,06699337 ! interaction with host GO:0051701 37 23 0,000 0,04884691 0,06695345 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04884691 0,06691357 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04884691 0,06687374 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04884691 0,06683396 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04884691 0,06679422 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,04884691 0,06675454 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04884691 0,0667149 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04884691 0,0666753 ! cell fate determination GO:0001709 45 23 0,000 0,04884691 0,06663576 ! pentose metabolic process GO:0019321 31 23 0,000 0,04884691 0,06659626 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04884691 0,0665568 ! spermatid development GO:0007286 33 23 0,000 0,04884691 0,0665174 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04884691 0,06647804 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04884691 0,06643872 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04884691 0,06639946 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04884691 0,06636024 ! telomere organization GO:0032200 32 23 0,000 0,04884691 0,06632106 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04884691 0,06628194 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04884691 0,06624286 ! regulation of amine transport GO:0051952 38 23 0,000 0,04884691 0,06620382 ! liver development GO:0001889 40 23 0,000 0,04884691 0,06616483 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,05091712 0,06892841 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,05091712 0,06888786 ! initiation of viral infection GO:0019059 42 24 0,000 0,05091712 0,06884737 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,05091712 0,06880691 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,05091712 0,06876651 ! superoxide metabolic process GO:0006801 32 24 0,000 0,05091712 0,06872616 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,05091712 0,06868585 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,05091712 0,06864559 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,05091712 0,06860537 ! fat cell differentiation GO:0045444 37 24 0,000 0,05091712 0,0685652 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,05091712 0,06852508 ! sperm motility GO:0030317 27 24 0,000 0,05091712 0,06848501 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,05091712 0,06844498 ! vacuole organization GO:0007033 39 24 0,000 0,05091712 0,06840501 ! receptor metabolic process GO:0043112 37 24 0,000 0,05091712 0,06836507 ! neural crest cell development GO:0014032 39 24 0,000 0,05091712 0,06832519 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,05091712 0,06828535 ! primary neural tube formation GO:0014020 35 24 0,000 0,05091712 0,06824555 ! negative regulation of cell development GO:0010721 56 24 0,000 0,05091712 0,06820581 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,05091712 0,06816611 ! base-excision repair GO:0006284 31 24 0,000 0,05091712 0,06812645 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,05091712 0,06808684 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,05091712 0,06804728 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,05091712 0,06800776 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,05091712 0,06796829 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,05298294 0,0706849 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,05298294 0,07064392 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,05298294 0,07060299 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,05298294 0,07056211 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,05298294 0,07052128 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,05298294 0,07048049 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,05298294 0,07043975 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,05298294 0,07039905 ! peptide transport GO:0015833 43 25 0,000 0,05298294 0,07035841 ! iron ion homeostasis GO:0055072 39 25 0,000 0,05298294 0,07031781 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,05298294 0,07027726 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,05298294 0,07023675 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,05298294 0,07019629 ! phospholipid transport GO:0015914 35 25 0,000 0,05298294 0,07015588 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,05298294 0,07011551 ! detection of light stimulus GO:0009583 30 25 0,000 0,05298294 0,07007519 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,05298294 0,07003492 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,05298294 0,06999469 ! leukocyte proliferation GO:0070661 39 25 0,000 0,05298294 0,06995451 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,05298294 0,06991438 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,05504439 0,07259294 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,05504439 0,07255134 ! translational initiation GO:0006413 43 26 0,000 0,05504439 0,07250979 ! regulation of pH GO:0006885 36 26 0,000 0,05504439 0,07246828 ! circadian rhythm GO:0007623 42 26 0,000 0,05504439 0,07242682 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,05504439 0,07238541 ! post-embryonic development GO:0009791 42 26 0,000 0,05504439 0,07234405 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,05504439 0,07230273 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,05504439 0,07226147 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,05504439 0,07222024 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,05504439 0,07217907 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,05504439 0,07213794 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,05504439 0,07209686 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,05504439 0,07205583 ! regulation of coagulation GO:0050818 39 26 0,000 0,05504439 0,07201484 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05710146 0,07466365 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,05710146 0,07462123 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05710146 0,07457885 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05710146 0,07453653 ! membrane docking GO:0022406 39 27 0,000 0,05710146 0,07449425 ! catechol metabolic process GO:0009712 43 27 0,000 0,05710146 0,07445202 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05710146 0,07440984 ! acute-phase response GO:0006953 42 27 0,000 0,05710146 0,0743677 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05710146 0,07432561 ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05710146 0,07428358 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05710146 0,07424158 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05710146 0,07419964 ! natural killer cell activation GO:0030101 35 27 0,000 0,05710146 0,07415774 ! lipid oxidation GO:0034440 38 27 0,000 0,05710146 0,07411589 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05710146 0,07407409 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05710146 0,07403233 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05710146 0,07399063 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05710146 0,07394896 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,05710146 0,07390735 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05710146 0,07386578 ! gene silencing GO:0016458 41 27 0,000 0,05710146 0,07382426 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05915418 0,07643517 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05915418 0,07639226 ! phenol metabolic process GO:0018958 44 28 0,000 0,05915418 0,07634939 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05915418 0,07630657 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05915418 0,07626379 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05915418 0,07622107 ! cell junction assembly GO:0034329 56 28 0,000 0,05915418 0,07617839 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05915418 0,07613576 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,05915418 0,07609318 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05915418 0,07605065 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05915418 0,07600816 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,05915418 0,07596572 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05915418 0,07592333 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05915418 0,07588099 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05915418 0,07583869 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05915418 0,07579644 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05915418 0,07575424 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05915418 0,07571208 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,05915418 0,07566997 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05915418 0,07562791 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05915418 0,07558589 GO:0008366|axon ensheathment, ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05915418 0,07554392 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05915418 0,075502 ! neural tube formation GO:0001841 41 28 0,000 0,05915418 0,07546013 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05915418 0,0754183 ! placenta development GO:0001890 37 28 0,000 0,05915418 0,07537651 ! regulation of B cell activation GO:0050864 42 28 0,000 0,05915418 0,07533478 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,06120254 0,0779003 ! regulation of innate immune response GO:0045088 38 29 0,000 0,06120254 0,07785721 ! ovulation cycle process GO:0022602 41 29 0,000 0,06120254 0,07781418 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,06120254 0,07777118 ! protein targeting to membrane GO:0006612 53 29 0,000 0,06120254 0,07772824 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,06120254 0,07768534 ! mismatch repair GO:0006298 34 29 0,000 0,06120254 0,07764249 ! telencephalon development GO:0021537 52 29 0,000 0,06120254 0,07759969 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,06120254 0,07755694 ! eye morphogenesis GO:0048592 51 29 0,000 0,06120254 0,07751423 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,06120254 0,07747157 ! tissue homeostasis GO:0001894 42 29 0,000 0,06120254 0,07742896 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,06324656 0,07997091 ! organic anion transport GO:0015711 51 30 0,000 0,06324656 0,07992697 ! cholesterol transport GO:0030301 46 30 0,000 0,06324656 0,07988308 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,06324656 0,07983924 ! spliceosome assembly GO:0000245 49 30 0,000 0,06324656 0,07979544 ! spindle organization GO:0007051 37 30 0,000 0,06324656 0,0797517 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,06324656 0,079708 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,06324656 0,07966434 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,06324656 0,07962074 ! ceramide metabolic process GO:0006672 43 30 0,000 0,06324656 0,07957718 ! ovulation cycle GO:0042698 43 30 0,000 0,06324656 0,07953368 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,06324656 0,07949021 ! adult locomotory behavior GO:0008344 47 30 0,000 0,06324656 0,0794468 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,06324656 0,07940343 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,06324656 0,07936012 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,06324656 0,07931684 ! response to heat GO:0009408 41 30 0,000 0,06324656 0,07927362 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,06324656 0,07923044 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,06324656 0,07918731 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,06528625 0,08169661 ! negative regulation of secretion GO:0051048 49 31 0,000 0,06528625 0,08165219 ! mammary gland development GO:0030879 57 31 0,000 0,06528625 0,08160781 ! glial cell differentiation GO:0010001 55 31 0,000 0,06528625 0,08156348 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,06528625 0,0815192 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,06528625 0,08147497 ! odontogenesis GO:0042476 50 31 0,000 0,06528625 0,08143079 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,06528625 0,08138665 ! segmentation GO:0035282 41 31 0,000 0,06528625 0,08134256 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,06528625 0,08129852 ! metanephros development GO:0001656 58 31 0,000 0,06528625 0,08125453 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,06528625 0,08121059 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,06528625 0,08116669 ! cell fate specification GO:0001708 37 31 0,000 0,06528625 0,08112284 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,06528625 0,08107904 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,06528625 0,08103528 ! RNA modification GO:0009451 40 31 0,000 0,06528625 0,08099157 ! regulation of muscle development GO:0048634 48 32 0,000 0,06732161 0,08347154 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06732161 0,08342657 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06732161 0,08338164 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06732161 0,08333676 ! meiosis I GO:0007127 52 32 0,000 0,06732161 0,08329194 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,06732161 0,08324716 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06732161 0,08320242 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,06732161 0,08315774 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,06732161 0,0831131 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06732161 0,08306851 ! regulation of protein stability GO:0031647 48 32 0,000 0,06732161 0,08302397 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,06732161 0,08297948 ! cytokine production GO:0001816 44 32 0,000 0,06732161 0,08293503 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,06732161 0,08289064 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06732161 0,08284629 ! vesicle localization GO:0051648 47 32 0,000 0,06732161 0,08280198 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,06935266 0,08525447 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,06935266 0,08520893 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,06935266 0,08516344 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06935266 0,08511799 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06935266 0,0850726 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,06935266 0,08502725 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06935266 0,08498195 ! cell junction organization GO:0034330 63 33 0,000 0,06935266 0,0849367 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06935266 0,08489149 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06935266 0,08484634 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06935266 0,08480123 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06935266 0,08475617 ! female gonad development GO:0008585 49 33 0,000 0,06935266 0,08471116 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06935266 0,0846662 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06935266 0,08462128 ! lipid homeostasis GO:0055088 55 33 0,000 0,06935266 0,08457641 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06935266 0,08453159 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06935266 0,08448682 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,06935266 0,0844421 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06935266 0,08439742 ! cytokinesis GO:0000910 52 33 0,000 0,06935266 0,08435279 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06935266 0,0843082 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,0713794 0,08672616 ! mRNA catabolic process GO:0006402 48 34 0,000 0,0713794 0,08668037 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,0713794 0,08663463 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,0713794 0,08658894 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,0713794 0,08654329 ! feeding behavior GO:0007631 45 34 0,000 0,0713794 0,08649769 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,0713794 0,08645214 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,0713794 0,08640664 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,0713794 0,08636119 ! neuron migration GO:0001764 46 34 0,000 0,0713794 0,08631578 ! female gamete generation GO:0007292 43 34 0,000 0,0713794 0,08627043 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,0713794 0,08622512 ! polyol metabolic process GO:0019751 44 34 0,000 0,0713794 0,08617985 ! aerobic respiration GO:0009060 47 34 0,000 0,0713794 0,08613464 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,0713794 0,08608947 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,0713794 0,08604435 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,0713794 0,08599928 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,07340184 0,08838965 ! Notch signaling pathway GO:0007219 56 35 0,000 0,07340184 0,0883434 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,07340184 0,0882972 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,07340184 0,08825104 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,07340184 0,08820493 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,07340184 0,08815887 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,07340184 0,08811286 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,07340184 0,0880669 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,07340184 0,08802098 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,07340184 0,08797511 ! glycogen metabolic process GO:0005977 48 35 0,000 0,07340184 0,08792929 ! pigment metabolic process GO:0042440 61 35 0,000 0,07340184 0,08788352 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,07340184 0,08783779 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,07542 0,09020593 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,07542 0,09015904 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,07542 0,0901122 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,07542 0,09006542 ! negative regulation of binding GO:0051100 58 36 0,000 0,07542 0,09001868 ! organic ether metabolic process GO:0018904 46 36 0,000 0,07542 0,08997199 ! tissue remodeling GO:0048771 62 36 0,000 0,07542 0,08992535 ! neural tube development GO:0021915 50 36 0,000 0,07542 0,08987875 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,07542 0,08983221 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,07542 0,08978571 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,07542 0,08973926 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,07542 0,08969286 ! glucan metabolic process GO:0044042 49 36 0,000 0,07542 0,08964651 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,07743387 0,09199272 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,07743387 0,09194523 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,07743387 0,09189778 ! learning GO:0007612 67 37 0,000 0,07743387 0,09185039 ! ion transmembrane transport GO:0034220 56 37 0,000 0,07743387 0,09180304 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,07743387 0,09175575 ! regulation of protein secretion GO:0050708 51 37 0,000 0,07743387 0,0917085 ! amino acid activation GO:0043038 52 37 0,000 0,07743387 0,0916613 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,07743387 0,09161415 ! gliogenesis GO:0042063 71 38 0,000 0,07944347 0,09394344 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,07944347 0,09389516 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,07944347 0,09384694 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,07944347 0,09379876 ! phagocytosis GO:0006909 60 38 0,000 0,07944347 0,09375064 ! mesenchymal cell development GO:0014031 64 38 0,000 0,07944347 0,09370256 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,07944347 0,09365453 ! maintenance of location in cell GO:0051651 69 38 0,000 0,07944347 0,09360655 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,08144881 0,09592026 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,08144881 0,09587117 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,08144881 0,09582213 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,08144881 0,09577314 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,08144881 0,09572421 ! chromatin remodeling GO:0006338 68 39 0,000 0,08144881 0,09567532 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,08144881 0,09562648 ! JNK cascade GO:0007254 54 39 0,000 0,08144881 0,09557769 ! developmental growth GO:0048589 62 39 0,000 0,08144881 0,09552895 ! synapse organization GO:0050808 55 39 0,000 0,08144881 0,09548026 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,0834499 0,09777625 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,0834499 0,09772646 ! regulation of tube size GO:0035150 60 40 0,000 0,0834499 0,09767673 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,0834499 0,09762704 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,0834499 0,09757741 ! peptide metabolic process GO:0006518 56 40 0,000 0,0834499 0,09752783 ! induction of apoptosis by intracellular signals GO:0008629 67 40 0,000 0,0834499 0,0974783 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,0834499 0,09742882 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,0834499 0,09737939 ! double-strand break repair GO:0006302 67 40 0,000 0,0834499 0,09733 ! B cell differentiation GO:0030183 62 40 0,000 0,0834499 0,09728067 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,0834499 0,09723139 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,0834499 0,09718216 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,08544674 0,09945724 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,08544674 0,09940693 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,08544674 0,09935668 ! glucose transport GO:0015758 52 41 0,000 0,08544674 0,09930647 ! endosome transport GO:0016197 71 41 0,000 0,08544674 0,09925632 ! striated muscle contraction GO:0006941 62 41 0,000 0,08544674 0,09920621 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,08544674 0,09915616 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,08544674 0,09910615 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,08544674 0,0990562 ! biopolymer methylation GO:0043414 62 41 0,000 0,08544674 0,0990063 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,08544674 0,09895645 ! mitochondrial transport GO:0006839 60 42 0,000 0,08743935 0,10121313 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,08743935 0,10116222 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,08743935 0,10111136 ! cellular component disassembly GO:0022411 64 42 0,000 0,08743935 0,10106055 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,08743935 0,10100979 ! hexose transport GO:0008645 54 42 0,000 0,08743935 0,10095908 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,08743935 0,10090843 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,08743935 0,10085782 ! excretion GO:0007588 63 42 0,000 0,08743935 0,10080727 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,08743935 0,10075676 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,08743935 0,10070631 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,08743935 0,1006559 ! regulation of cell shape GO:0008360 78 42 0,000 0,08743935 0,10060555 ! positive regulation of binding GO:0051099 59 43 0,000 0,08942772 0,10284188 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,08942772 0,10279049 ! leukocyte migration GO:0050900 60 43 0,000 0,08942772 0,10273914 ! neuromuscular process GO:0050905 79 43 0,000 0,08942772 0,10268785 ! activation of caspase activity GO:0006919 65 43 0,000 0,08942772 0,10263661 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,08942772 0,10258542 ! tRNA processing GO:0008033 49 43 0,000 0,08942772 0,10253428 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,08942772 0,10248319 ! vesicle organization GO:0016050 79 43 0,000 0,08942772 0,10243215 ! response to insulin stimulus GO:0032868 63 43 0,000 0,08942772 0,10238117 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,08942772 0,10233023 ! methylation GO:0032259 64 43 0,000 0,08942772 0,10227935 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,09141188 0,10449668 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,09141188 0,10444477 ! glycolysis GO:0006096 53 44 0,000 0,09141188 0,10439291 ! regulation of action potential GO:0001508 71 44 0,000 0,09141188 0,10434111 ! regulation of ion transport GO:0043269 57 44 0,000 0,09141188 0,10428935 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,09141188 0,10423764 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,09141188 0,10418599 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,09141188 0,10413439 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,09141188 0,10408284 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,09141188 0,10403134 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,09141188 0,10397989 ! RNA catabolic process GO:0006401 64 45 0,000 0,09339183 0,10617954 ! positive regulation of defense response GO:0031349 59 45 0,000 0,09339183 0,10612708 ! regulation of translational initiation GO:0006446 64 45 0,000 0,09339183 0,10607467 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,09339183 0,10602232 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,09339183 0,10597001 ! cell recognition GO:0008037 58 45 0,000 0,09339183 0,10591776 ! cell maturation GO:0048469 60 45 0,000 0,09339183 0,10586556 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,09536758 0,10805194 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,09536758 0,10799874 ! cell redox homeostasis GO:0045454 63 46 0,000 0,09536758 0,10794559 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,09536758 0,10789249 ! histone modification GO:0016570 68 46 0,000 0,09536758 0,10783944 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,09536758 0,10778645 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,09733913 0,10996071 ! viral infectious cycle GO:0019058 71 47 0,000 0,09733913 0,10990673 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,09733913 0,1098528 ! endocrine system development GO:0035270 83 47 0,000 0,09733913 0,10979892 ! covalent chromatin modification GO:0016569 75 47 0,000 0,09733913 0,1097451 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,09733913 0,10969133 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,09733913 0,10963761 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,09733913 0,10958395 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,09733913 0,10953034 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,09733913 0,10947678 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,09733913 0,10942327 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,0993065 0,11158034 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,0993065 0,11152586 ! response to temperature stimulus GO:0009266 62 48 0,000 0,0993065 0,11147143 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,0993065 0,11141705 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,0993065 0,11136273 ! heart morphogenesis GO:0003007 65 48 0,000 0,0993065 0,11130846 ! regulation of DNA replication GO:0006275 75 48 0,000 0,0993065 0,11125424 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,0993065 0,11120008 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,0993065 0,11114597 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,0993065 0,11109191 ! regulation of endocytosis GO:0030100 63 48 0,000 0,0993065 0,1110379 ! nuclear export GO:0051168 69 48 0,000 0,0993065 0,11098395 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,0993065 0,11093004 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,0993065 0,11087619 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,1012697 0,11301325 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,1012697 0,11295844 ! sensory perception of smell GO:0007608 61 49 0,000 0,1012697 0,11290369 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,1012697 0,11284899 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,1012697 0,11279434 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,1012697 0,11273974 ! germ cell development GO:0007281 68 49 0,000 0,1012697 0,1126852 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,1012697 0,11263071 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,1012697 0,11257627 ! maintenance of location GO:0051235 84 49 0,000 0,1012697 0,11252189 ! regulation of actin filament length GO:0030832 72 50 0,000 0,10322873 0,1146432 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,10322873 0,11458788 ! membrane fusion GO:0006944 80 50 0,000 0,10322873 0,1145326 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,10322873 0,11447738 ! lipid modification GO:0030258 73 50 0,000 0,10322873 0,11442221 ! positive regulation of growth GO:0045927 67 50 0,000 0,10322873 0,11436709 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,10322873 0,11431203 ! proton transport GO:0015992 75 50 0,000 0,10322873 0,11425701 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,10322873 0,11420206 ! positive regulation of secretion GO:0051047 71 51 0,000 0,1051836 0,11630879 ! hydrogen transport GO:0006818 77 51 0,000 0,1051836 0,1162529 ! muscle fiber development GO:0048747 74 51 0,000 0,1051836 0,11619706 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,1051836 0,11614128 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,1051836 0,11608555 ! adult behavior GO:0030534 80 51 0,000 0,1051836 0,11602987 ! transition metal ion transport GO:0000041 74 52 0,000 0,10713432 0,11812509 ! regulation of cellular component size GO:0032535 74 52 0,000 0,10713432 0,11806849 ! aging GO:0007568 79 52 0,000 0,10713432 0,11801194 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,10713432 0,11795545 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,10713432 0,11789901 ! establishment of organelle localization GO:0051656 85 52 0,000 0,10713432 0,11784263 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,1090809 0,11992642 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,1090809 0,11986912 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,1090809 0,11981188 ! kidney development GO:0001822 90 53 0,000 0,1090809 0,11975469 ! single fertilization GO:0007338 59 53 0,000 0,1090809 0,11969755 ! cell projection assembly GO:0030031 76 53 0,000 0,1090809 0,11964047 ! amino acid transport GO:0006865 84 54 0,000 0,11102335 0,12171292 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,11102335 0,12165493 ! regulation of mitosis GO:0007088 84 54 0,000 0,11102335 0,121597 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,11102335 0,12153913 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,11102335 0,12148131 ! DNA catabolic process GO:0006308 67 54 0,000 0,11102335 0,12142354 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,11102335 0,12136583 ! exocytosis GO:0006887 74 55 0,000 0,11296167 0,12342606 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,11296167 0,12336745 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,11296167 0,1233089 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,11489588 0,12536078 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,11489588 0,12530134 ! carbohydrate transport GO:0008643 74 57 0,000 0,11682598 0,12734586 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,11682598 0,12728553 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,11682598 0,12722527 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,11682598 0,12716506 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,11682598 0,1271049 ! camera-type eye development GO:0043010 88 57 0,000 0,11682598 0,12704481 ! secondary metabolic process GO:0019748 84 57 0,000 0,11682598 0,12698477 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,11682598 0,12692478 ! viral reproductive process GO:0022415 87 58 0,000 0,11875199 0,12895636 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,11875199 0,1288955 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,11875199 0,1288347 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,1206739 0,13085807 ! activation of MAPK activity GO:0000187 84 59 0,000 0,1206739 0,13079641 ! actin filament organization GO:0007015 95 59 0,000 0,1206739 0,1307348 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,1206739 0,13067325 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,12259173 0,13268752 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,12259173 0,13262511 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,12259173 0,13256276 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,12259173 0,13250046 ! regulation of heart contraction GO:0008016 91 60 0,000 0,12259173 0,13243823 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,12259173 0,13237605 ! fertilization GO:0009566 68 60 0,000 0,12259173 0,13231393 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,12259173 0,13225187 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,12450549 0,13425346 ! meiosis GO:0007126 96 61 0,000 0,12450549 0,13419055 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,12450549 0,1341277 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,12450549 0,1340649 ! urogenital system development GO:0001655 101 61 0,000 0,12450549 0,13400217 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,12450549 0,13393949 ! extracellular matrix organization GO:0030198 103 61 0,000 0,12450549 0,13387687 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,12450549 0,13381432 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,12450549 0,13375181 ! amine catabolic process GO:0009310 90 62 0,000 0,12641519 0,13573993 ! neurotransmitter transport GO:0006836 81 62 0,000 0,12641519 0,13567659 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,12641519 0,13561331 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,12641519 0,13555009 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,12641519 0,13548692 ! meiotic cell cycle GO:0051321 97 62 0,000 0,12641519 0,13542382 ! organelle localization GO:0051640 96 62 0,000 0,12641519 0,13536077 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,12832083 0,13733732 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,12832083 0,13727344 ! viral reproduction GO:0016032 92 63 0,000 0,12832083 0,13720962 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,13022242 0,13917823 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,13022242 0,13911359 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,13022242 0,13904901 ! hexose catabolic process GO:0019320 82 64 0,000 0,13022242 0,13898448 ! adaptive immune response GO:0002250 94 64 0,000 0,13022242 0,13892002 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! B cell activation GO:0042113 104 65 0,000 0,13211997 0,14087897 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,13211997 0,14081368 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,13211997 0,14074846 ! defense response to bacterium GO:0042742 73 65 0,000 0,13211997 0,1406833 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,13211997 0,1406182 ! activation of immune response GO:0002253 83 65 0,000 0,13211997 0,14055316 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,13401349 0,14250163 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,13401349 0,14243578 ! antigen processing and presentation GO:0019882 96 66 0,000 0,13401349 0,14236999 ! axon guidance GO:0007411 99 66 0,000 0,13401349 0,14230426 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,13401349 0,14223859 ! regulation of immune effector process GO:0002697 101 66 0,000 0,13401349 0,14217298 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,13590299 0,14411105 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,13590299 0,14404464 ! acute inflammatory response GO:0002526 92 68 0,000 0,13778847 0,14597581 ! learning or memory GO:0007611 123 68 0,000 0,13778847 0,1459086 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,13778847 0,14584145 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,13778847 0,14577437 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,13778847 0,14570735 ! rhythmic process GO:0048511 105 68 0,000 0,13778847 0,14564039 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,13966995 0,14756127 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,13966995 0,14749352 ! response to drug GO:0042493 108 69 0,000 0,13966995 0,14742583 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,13966995 0,1473582 ! humoral immune response GO:0006959 86 70 0,000 0,14154743 0,14927055 ! eye development GO:0001654 111 70 0,000 0,14154743 0,14920214 ! amine transport GO:0015837 101 70 0,000 0,14154743 0,1491338 ! regulation of catabolic process GO:0009894 106 70 0,000 0,14154743 0,14906551 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,14342091 0,15096938 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,14342091 0,15090032 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,14342091 0,15083132 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,14342091 0,15076239 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,14342091 0,15069351 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,14342091 0,1506247 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,14529042 0,15251847 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,14529042 0,15244889 ! negative regulation of transport GO:0051051 116 73 0,000 0,14715596 0,15433593 ! regulation of blood pressure GO:0008217 107 73 0,000 0,14715596 0,15426559 ! tube morphogenesis GO:0035239 118 73 0,000 0,14715596 0,15419531 ! mitochondrion organization GO:0007005 104 73 0,000 0,14715596 0,15412509 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,14715596 0,15405494 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,14715596 0,15398485 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,14901753 0,1558619 ! digestion GO:0007586 97 74 0,000 0,14901753 0,15579105 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,14901753 0,15572027 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,14901753 0,15564955 ! blood coagulation GO:0007596 116 75 0,000 0,15087514 0,1575183 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,15087514 0,15744683 ! regulation of ligase activity GO:0051340 114 75 0,000 0,15087514 0,15737543 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,15087514 0,15730409 ! amine biosynthetic process GO:0009309 97 76 0,000 0,15272881 0,15916459 ! tRNA metabolic process GO:0006399 95 76 0,000 0,15272881 0,15909251 ! response to unfolded protein GO:0006986 99 76 0,000 0,15272881 0,15902049 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,15272881 0,15894853 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,15457853 0,16080082 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,15457853 0,16072813 ! regulation of DNA binding GO:0051101 119 77 0,000 0,15457853 0,1606555 ! gland development GO:0048732 148 77 0,000 0,15457853 0,16058294 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,15457853 0,16051044 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,15457853 0,16043801 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,15457853 0,16036564 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,15642432 0,16220737 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,15642432 0,16213427 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,15642432 0,16206124 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,15826619 0,16389565 ! cellular respiration GO:0045333 107 79 0,000 0,15826619 0,16382189 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,15826619 0,1637482 ! T cell activation GO:0042110 134 79 0,000 0,15826619 0,16367457 ! regulation of lyase activity GO:0051339 133 79 0,000 0,15826619 0,16360101 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,15826619 0,16352751 ! chromatin assembly GO:0031497 102 80 0,000 0,16010414 0,16535228 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,16010414 0,16527807 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,16010414 0,16520392 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,16010414 0,16512983 ! forebrain development GO:0030900 131 80 0,000 0,16010414 0,16505582 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,16193819 0,16687179 ! hemostasis GO:0007599 125 81 0,000 0,16193819 0,16679706 ! mRNA transport GO:0051028 121 81 0,000 0,16193819 0,1667224 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,16193819 0,1666478 ! response to protein stimulus GO:0051789 111 81 0,000 0,16193819 0,16657327 ! regulation of neurological system process GO:0031644 122 81 0,000 0,16193819 0,16649881 ! vitamin metabolic process GO:0006766 103 81 0,000 0,16193819 0,16642441 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,16193819 0,16635008 GO:0002696|positive regulation of leukocyte activation, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,16559459 0,17003016 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,16559459 0,16995428 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,16559459 0,16987848 ! regulation of defense response GO:0031347 117 84 0,000 0,16741696 0,17167142 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,16741696 0,17159492 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,16741696 0,17151848 ! sterol metabolic process GO:0016125 120 84 0,000 0,16741696 0,17144212 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,16923545 0,17322721 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,16923545 0,17315015 ! rRNA metabolic process GO:0016072 107 85 0,000 0,16923545 0,17307316 GO:0006364|rRNA processing, ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,16923545 0,17299624 ! regulation of membrane potential GO:0042391 128 85 0,000 0,16923545 0,17291938 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,16923545 0,1728426 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,17105008 0,17461836 ! nucleosome organization GO:0034728 114 87 0,000 0,17286084 0,17638861 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,17286084 0,17631039 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,17286084 0,17623224 ! skeletal muscle tissue development GO:0007519 123 87 0,000 0,17286084 0,17615416 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 0,000 0,17286084 0,17607615 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,17286084 0,1759982 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,17466776 0,17775922 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,17466776 0,1776806 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,17466776 0,17760205 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,17466776 0,17752357 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,17466776 0,17744516 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,17647083 0,17919775 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,17647083 0,17911867 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,17647083 0,17903966 ! regulation of T cell activation GO:0050863 128 89 0,000 0,17647083 0,17896072 ! leukocyte differentiation GO:0002521 143 90 0,000 0,17827006 0,18070566 ! hormone metabolic process GO:0042445 121 90 0,000 0,17827006 0,18062606 ! RNA localization GO:0006403 135 91 0,000 0,18006547 0,18236486 ! ATP metabolic process GO:0046034 137 91 0,000 0,18006547 0,18228459 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,18185706 0,18401726 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,18185706 0,18393634 ! positive regulation of immune response GO:0050778 121 92 0,000 0,18185706 0,18385549 ! DNA recombination GO:0006310 146 92 0,000 0,18185706 0,18377471 ! sulfur metabolic process GO:0006790 118 92 0,000 0,18185706 0,183694 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,18364484 0,1854184 ! peptidyl-amino acid modification GO:0018193 147 93 0,000 0,18364484 0,18533704 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,18364484 0,18525576 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,18364484 0,18517454 ! electron transport chain GO:0022900 123 94 0,000 0,18542881 0,18689144 ! regulation of binding GO:0051098 151 95 0,000 0,18720899 0,18860301 ! carboxylic acid transport GO:0046942 147 95 0,000 0,18720899 0,18852043 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,18898537 0,19022598 ! in utero embryonic development GO:0001701 147 96 0,000 0,18898537 0,19014276 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,18898537 0,19005962 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,18898537 0,18997656 ! protein maturation GO:0051604 129 96 0,000 0,18898537 0,18989356 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,19075798 0,19159099 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,19075798 0,19150736 ! calcium ion transport GO:0006816 167 99 0,000 0,19429189 0,19497004 ! extracellular structure organization GO:0043062 156 99 0,000 0,19429189 0,19488501 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,19429189 0,19480006 ! regulation of translation GO:0006417 151 100 0,000 0,1960532 0,19648033 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,1960532 0,19639476 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,1960532 0,19630926 ! divalent metal ion transport GO:0070838 171 100 0,000 0,1960532 0,19622383 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,1960532 0,19613848 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,1960532 0,1960532