pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/658-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 12 6 2,000 2,392E-08 5,754E-05 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 2,392E-08 2,877E-05 GO:0031272|regulation of pseudopodium assembly, ! regulation of lipid kinase activity GO:0043550 13 7 2,000 4,182E-08 3,354E-05 ! macrophage differentiation GO:0030225 11 7 2,000 4,182E-08 2,516E-05 ! establishment of nucleus localization GO:0040023 16 8 2,000 6,686E-08 3,218E-05 ! nucleus localization GO:0051647 19 11 2,000 1,966E-07 7,883E-05 ! regulation of cell projection assembly GO:0060491 30 12 2,000 2,619E-07 9,002E-05 ! regulation of protein complex assembly GO:0043254 117 61 3,000 5,963E-07 1,793E-04 ! filopodium assembly GO:0046847 32 16 2,000 6,647E-07 1,777E-04 ! myeloid cell differentiation GO:0030099 111 65 3,000 7,712E-07 1,856E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 8,065E-07 1,764E-04 ! microspike assembly GO:0030035 36 17 2,000 8,065E-07 1,617E-04 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 9,671E-07 1,79E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,349E-06 2,318E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,349E-06 2,164E-04 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,349E-06 2,029E-04 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 1,82E-06 2,575E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,091E-06 2,795E-04 ! regulation of protein transport GO:0051223 154 87 3,000 2,493E-06 3,157E-04 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cell projection organization GO:0031346 58 27 2,000 3,443E-06 4,142E-04 ! regulation of protein localization GO:0032880 176 97 3,000 3,851E-06 4,412E-04 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 4,295E-06 4,697E-04 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 9,079E-06 9,497E-04 ! glycogen metabolic process GO:0005977 61 37 2,000 9,079E-06 9,101E-04 ! glucan metabolic process GO:0044042 62 38 2,000 9,849E-06 9,479E-04 GO:0006073|cellular glucan metabolic process, ! anagen GO:0042640 6 5 1,000 1,162E-05 1,075E-03 ! response to food GO:0032094 6 5 1,000 1,162E-05 1,035E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 1,162E-05 9,984E-04 ! carnitine metabolic process GO:0009437 7 5 1,000 1,162E-05 9,64E-04 GO:0006577|betaine metabolic process, ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,336E-05 1,072E-03 ! energy reserve metabolic process GO:0006112 74 43 2,000 1,436E-05 1,114E-03 ! protein refolding GO:0042026 15 6 1,000 1,742E-05 1,309E-03 ! hair follicle maturation GO:0048820 7 6 1,000 1,742E-05 1,27E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 1,742E-05 1,232E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,762E-05 1,211E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,762E-05 1,177E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,004E-05 1,303E-03 ! response to temperature stimulus GO:0009266 76 49 2,000 2,134E-05 1,351E-03 ! regulation of cell projection organization GO:0031344 121 50 2,000 2,268E-05 1,399E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,437E-05 1,466E-03 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 2,437E-05 1,43E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 2,437E-05 1,396E-03 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 3,024E-05 1,692E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,247E-05 1,775E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 3,247E-05 1,736E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 3,247E-05 1,698E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! ER overload response GO:0006983 12 8 1,000 3,247E-05 1,662E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 3,247E-05 1,627E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,368E-05 1,654E-03 ! establishment of organelle localization GO:0051656 109 59 2,000 3,737E-05 1,798E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 4,171E-05 1,968E-03 GO:0010469|regulation of receptor activity, ! microtubule bundle formation GO:0001578 21 9 1,000 4,171E-05 1,93E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 4,171E-05 1,894E-03 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 4,551E-05 2,028E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 5,211E-05 2,279E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 5,211E-05 2,239E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 5,211E-05 2,199E-03 GO:0005978|glycogen biosynthetic process, ! developmental maturation GO:0021700 116 66 2,000 5,232E-05 2,17E-03 ! cell projection assembly GO:0030031 120 66 2,000 5,232E-05 2,134E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 6,364E-05 2,552E-03 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 6,364E-05 2,51E-03 GO:0010812|negative regulation of cell-substrate adhesion, ! cardiac cell differentiation GO:0035051 31 11 1,000 6,364E-05 2,47E-03 ! organelle localization GO:0051640 136 74 2,000 7,368E-05 2,814E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 7,632E-05 2,869E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 7,632E-05 2,825E-03 ! entry into host cell GO:0030260 32 12 1,000 7,632E-05 2,782E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! T cell homeostasis GO:0043029 25 12 1,000 7,632E-05 2,741E-03 ! response to cold GO:0009409 17 12 1,000 7,632E-05 2,7E-03 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 9,013E-05 3,143E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 9,013E-05 3,098E-03 ! mitochondrion organization GO:0007005 148 86 2,000 1,153E-04 3,907E-03 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,212E-04 4,049E-03 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,212E-04 3,993E-03 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 1,384E-04 4,499E-03 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,384E-04 4,439E-03 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,384E-04 4,381E-03 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,384E-04 4,324E-03 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,567E-04 4,834E-03 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,567E-04 4,773E-03 ! leukocyte differentiation GO:0002521 202 96 2,000 1,598E-04 4,805E-03 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 1,762E-04 5,233E-03 ! positive regulation of proteolysis GO:0045862 31 18 1,000 1,762E-04 5,17E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,185E-04 6,334E-03 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 2,185E-04 6,258E-03 ! collagen catabolic process GO:0030574 28 21 1,000 2,413E-04 6,831E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,653E-04 7,422E-03 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,653E-04 7,336E-03 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,653E-04 7,253E-03 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 2,903E-04 7,849E-03 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,903E-04 7,762E-03 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 2,903E-04 7,677E-03 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 2,903E-04 7,593E-03 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,165E-04 8,189E-03 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 3,165E-04 8,102E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,165E-04 8,016E-03 ! leukocyte homeostasis GO:0001776 44 24 1,000 3,165E-04 7,933E-03 ! vasculogenesis GO:0001570 46 25 1,000 3,438E-04 8,528E-03 ! response to starvation GO:0042594 42 25 1,000 3,438E-04 8,441E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,438E-04 8,356E-03 ! coenzyme catabolic process GO:0009109 39 25 1,000 3,438E-04 8,272E-03 ! interaction with host GO:0051701 62 25 1,000 3,438E-04 8,19E-03 ! liver development GO:0001889 53 25 1,000 3,438E-04 8,11E-03 ! initiation of viral infection GO:0019059 57 26 1,000 3,722E-04 8,695E-03 ! acetyl-CoA metabolic process GO:0006084 39 26 1,000 3,722E-04 8,611E-03 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 3,722E-04 8,529E-03 ! molting cycle process GO:0022404 50 26 1,000 3,722E-04 8,448E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 3,722E-04 8,37E-03 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 3,722E-04 8,292E-03 ! positive regulation of nuclear division GO:0051785 40 26 1,000 3,722E-04 8,216E-03 GO:0045840|positive regulation of mitosis, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 4,017E-04 8,787E-03 ! mitochondrial membrane organization GO:0007006 57 27 1,000 4,017E-04 8,707E-03 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 4,017E-04 8,63E-03 ! dendrite development GO:0016358 59 28 1,000 4,323E-04 9,205E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 4,323E-04 9,124E-03 ! lipid oxidation GO:0034440 43 28 1,000 4,323E-04 9,045E-03 GO:0019395|fatty acid oxidation, ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 4,64E-04 9,624E-03 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 4,64E-04 9,542E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 4,968E-04 0,01013017 ! cofactor catabolic process GO:0051187 51 30 1,000 4,968E-04 0,01004504 ! response to heat GO:0009408 50 30 1,000 4,968E-04 9,961E-03 ! collagen metabolic process GO:0032963 45 31 1,000 5,307E-04 0,01055309 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 5,307E-04 0,01046658 ! fatty acid catabolic process GO:0009062 48 31 1,000 5,307E-04 0,01038149 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 5,657E-04 0,01097676 ! positive regulation of catabolic process GO:0009896 64 32 1,000 5,657E-04 0,01088895 ! post-embryonic development GO:0009791 69 33 1,000 6,018E-04 0,01149159 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 6,39E-04 0,01210537 ! placenta development GO:0001890 53 34 1,000 6,39E-04 0,0120108 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 6,39E-04 0,01191769 ! negative regulation of secretion GO:0051048 63 35 1,000 6,772E-04 0,01253416 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 6,772E-04 0,01243848 ! regulation of microtubule-based process GO:0032886 78 35 1,000 6,772E-04 0,01234425 ! regulation of proteolysis GO:0030162 72 36 1,000 7,166E-04 0,01296322 ! aerobic respiration GO:0009060 55 36 1,000 7,166E-04 0,01286648 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 7,57E-04 0,01349171 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 8,848E-04 0,01565272 ! cytokinesis GO:0000910 72 40 1,000 8,848E-04 0,01553846 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 9,753E-04 0,01700448 ! regulation of protein secretion GO:0050708 71 42 1,000 9,753E-04 0,01688214 ! glucose transport GO:0015758 65 43 1,000 1,022E-03 0,01756716 ! striated muscle cell differentiation GO:0051146 82 43 1,000 1,022E-03 0,01744257 ! hexose transport GO:0008645 67 44 1,000 1,07E-03 0,01813206 GO:0015749|monosaccharide transport, ! developmental growth GO:0048589 82 44 1,000 1,07E-03 0,01800526 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 1,119E-03 0,01869906 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 1,119E-03 0,0185701 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 1,119E-03 0,01844291 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 1,169E-03 0,01913695 ! response to insulin stimulus GO:0032868 95 46 1,000 1,169E-03 0,01900764 ! regulation of JNK cascade GO:0046328 94 47 1,000 1,22E-03 0,01970569 ! protein homooligomerization GO:0051260 76 47 1,000 1,22E-03 0,01957432 ! mitochondrial transport GO:0006839 82 48 1,000 1,273E-03 0,02027623 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 1,273E-03 0,02014283 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 1,326E-03 0,02084844 ! viral infectious cycle GO:0019058 99 51 1,000 1,435E-03 0,02242604 ! regulation of cell shape GO:0008360 125 51 1,000 1,435E-03 0,02228136 ! positive regulation of growth GO:0045927 90 52 1,000 1,492E-03 0,02300832 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 1,492E-03 0,02286177 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 1,549E-03 0,02359179 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 1,549E-03 0,02344341 ! regulation of protein polymerization GO:0032271 103 53 1,000 1,549E-03 0,02329689 ! response to UV GO:0009411 104 53 1,000 1,549E-03 0,02315219 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 1,608E-03 0,0238779 ! regulation of protein catabolic process GO:0042176 116 55 1,000 1,667E-03 0,02461009 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 1,667E-03 0,02446002 ! regulation of actin filament length GO:0030832 105 56 1,000 1,728E-03 0,02519497 ! positive regulation of organelle organization GO:0010638 100 56 1,000 1,728E-03 0,0250432 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 1,789E-03 0,0257808 ! lipid modification GO:0030258 97 57 1,000 1,789E-03 0,02562734 ! regulation of cellular component size GO:0032535 109 59 1,000 1,916E-03 0,02727401 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 1,916E-03 0,02711358 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 1,98E-03 0,02786543 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 2,046E-03 0,02862294 ! viral reproductive process GO:0022415 126 62 1,000 2,113E-03 0,02938596 ! water-soluble vitamin metabolic process GO:0006767 95 62 1,000 2,113E-03 0,02921708 ! regulation of mitosis GO:0007088 105 63 1,000 2,181E-03 0,02998207 GO:0051783|regulation of nuclear division, ! germ cell development GO:0007281 118 65 1,000 2,319E-03 0,03170692 ! regulation of cellular response to stress GO:0080135 128 67 1,000 2,462E-03 0,03346763 ! activation of MAPK activity GO:0000187 115 67 1,000 2,462E-03 0,03327961 ! homeostasis of number of cells GO:0048872 114 67 1,000 2,462E-03 0,03309369 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 2,462E-03 0,03290984 ! viral reproduction GO:0016032 134 68 1,000 2,535E-03 0,03369672 ! negative regulation of cell size GO:0045792 134 69 1,000 2,609E-03 0,03448834 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 2,76E-03 0,03628249 ! regulation of caspase activity GO:0043281 122 72 1,000 2,837E-03 0,03709095 ! carbohydrate transport GO:0008643 110 72 1,000 2,837E-03 0,03689046 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 2,993E-03 0,03872067 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 2,993E-03 0,03851361 ! regulation of catabolic process GO:0009894 161 76 1,000 3,154E-03 0,04036683 ! regulation of actin filament-based process GO:0032970 152 77 1,000 3,236E-03 0,04119584 ! negative regulation of organelle organization GO:0010639 161 78 1,000 3,319E-03 0,04202869 ! protein oligomerization GO:0051259 139 78 1,000 3,319E-03 0,04180864 ! activation of protein kinase activity GO:0032147 147 79 1,000 3,403E-03 0,04264203 ! regulation of peptidase activity GO:0052547 134 79 1,000 3,403E-03 0,04242108 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 3,403E-03 0,04220242 ! muscle cell differentiation GO:0042692 159 80 1,000 3,488E-03 0,04303315 ! cellular lipid catabolic process GO:0044242 134 80 1,000 3,488E-03 0,04281359 ! protein import into nucleus GO:0006606 158 80 1,000 3,488E-03 0,04259626 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 3,574E-03 0,04342439 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 3,574E-03 0,04320618 ! nuclear import GO:0051170 161 81 1,000 3,574E-03 0,04299015 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 3,66E-03 0,04381573 ! response to oxygen levels GO:0070482 176 83 1,000 3,748E-03 0,04464483 ! negative regulation of transport GO:0051051 153 84 1,000 3,837E-03 0,04547736 ! response to unfolded protein GO:0006986 131 85 1,000 3,927E-03 0,04631326 ! tube morphogenesis GO:0035239 176 86 1,000 4,018E-03 0,04715244 ! protein localization in nucleus GO:0034504 176 87 1,000 4,109E-03 0,04799484 ! cellular respiration GO:0045333 135 88 1,000 4,202E-03 0,04884039 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 4,296E-03 0,04968901 ! regulation of cell adhesion GO:0030155 212 89 1,000 4,296E-03 0,04945126 ! regulation of cell cycle process GO:0010564 149 90 1,000 4,39E-03 0,05029996 ! response to protein stimulus GO:0051789 149 91 1,000 4,486E-03 0,05115162 ! vitamin metabolic process GO:0006766 139 92 1,000 4,582E-03 0,05200616 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 4,68E-03 0,05286353 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 4,68E-03 0,0526165 ! biogenic amine metabolic process GO:0006576 155 94 1,000 4,778E-03 0,05347377 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 4,878E-03 0,05433376 ! protein ubiquitination GO:0016567 217 97 1,000 5,08E-03 0,05631997 ! interphase GO:0051325 213 98 1,000 5,182E-03 0,05719053 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 5,182E-03 0,05692939 GO:0016054|organic acid catabolic process, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 5,467E-03 0,05978913 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 5,467E-03 0,05951859 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 5,467E-03 0,05925049 ! positive regulation of helicase activity GO:0051096 11 5 0,000 5,467E-03 0,05898479 ! neuron fate determination GO:0048664 7 5 0,000 5,467E-03 0,05872147 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 5,467E-03 0,05846048 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 5,467E-03 0,05820181 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 5,467E-03 0,05794541 ! polyol transport GO:0015791 12 5 0,000 5,467E-03 0,05769126 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 5,467E-03 0,05743934 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 5,467E-03 0,0571896 ! response to superoxide GO:0000303 10 5 0,000 5,467E-03 0,05694203 ! negative regulation of bone resorption GO:0045779 10 5 0,000 5,467E-03 0,05669659 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 5,467E-03 0,05645325 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 5,467E-03 0,056212 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 5,467E-03 0,0559728 ! female meiosis GO:0007143 7 5 0,000 5,467E-03 0,05573563 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 5,467E-03 0,05550046 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 5,467E-03 0,05526726 ! cobalt ion transport GO:0006824 11 5 0,000 5,467E-03 0,05503602 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 5,467E-03 0,0548067 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 5,467E-03 0,05457929 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 5,467E-03 0,05435375 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 5,467E-03 0,05413007 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 5,467E-03 0,05390823 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 5,467E-03 0,0536882 ! embryonic camera-type eye development GO:0031076 10 5 0,000 5,467E-03 0,05346995 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 5,467E-03 0,05325347 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 5,467E-03 0,05303874 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 5,467E-03 0,05282574 ! adaptation of signaling pathway GO:0022401 7 5 0,000 5,467E-03 0,05261443 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 5,467E-03 0,05240481 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 5,467E-03 0,05219686 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 5,467E-03 0,05199055 ! negative chemotaxis GO:0050919 14 5 0,000 5,467E-03 0,05178586 ! positive regulation of histone modification GO:0031058 5 5 0,000 5,467E-03 0,05158278 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 5,467E-03 0,05138128 ! sensory perception of bitter taste GO:0050913 7 5 0,000 5,467E-03 0,05118135 ! behavioral response to pain GO:0048266 9 5 0,000 5,467E-03 0,05098298 ! clathrin coat assembly GO:0048268 14 5 0,000 5,467E-03 0,05078613 ! Notch receptor processing GO:0007220 8 5 0,000 5,467E-03 0,0505908 ! regulation of dopamine uptake GO:0051584 9 5 0,000 5,467E-03 0,05039697 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 5,467E-03 0,05020461 ! micturition GO:0060073 9 5 0,000 5,467E-03 0,05001372 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 5,467E-03 0,04982427 ! copulation GO:0007620 9 5 0,000 5,467E-03 0,04963626 ! glial cell fate commitment GO:0021781 13 5 0,000 5,467E-03 0,04944965 ! protein maturation by protein folding GO:0022417 13 5 0,000 5,467E-03 0,04926445 ! spermidine metabolic process GO:0008216 7 5 0,000 5,467E-03 0,04908063 ! regulation of potassium ion transport GO:0043266 10 5 0,000 5,467E-03 0,04889817 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 5,467E-03 0,04871707 ! apoptotic cell clearance GO:0043277 20 5 0,000 5,467E-03 0,0485373 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 5,467E-03 0,04835885 ! lipoprotein particle clearance GO:0034381 10 5 0,000 5,467E-03 0,04818172 ! grooming behavior GO:0007625 6 5 0,000 5,467E-03 0,04800587 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 5,467E-03 0,0478313 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 5,467E-03 0,047658 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 5,467E-03 0,04748595 ! response to protozoan GO:0001562 10 5 0,000 5,467E-03 0,04731514 ! positive regulation of glycolysis GO:0045821 14 5 0,000 5,467E-03 0,04714555 ! lymph vessel development GO:0001945 10 5 0,000 5,467E-03 0,04697717 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 5,467E-03 0,04680999 ! endochondral ossification GO:0001958 16 5 0,000 5,467E-03 0,046644 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 5,467E-03 0,04647918 ! parathyroid gland development GO:0060017 13 5 0,000 5,467E-03 0,04631552 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 5,467E-03 0,04615301 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 5,467E-03 0,04599164 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 5,467E-03 0,04583139 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 5,467E-03 0,04567225 ! dorsal spinal cord development GO:0021516 7 5 0,000 5,467E-03 0,04551422 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 5,467E-03 0,04535727 ! sphingoid catabolic process GO:0046521 6 5 0,000 5,467E-03 0,0452014 ! skeletal myofibril assembly GO:0014866 10 5 0,000 5,467E-03 0,0450466 ! smooth muscle tissue development GO:0048745 28 5 0,000 5,467E-03 0,04489286 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 5,467E-03 0,04474016 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 5,467E-03 0,0445885 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 5,467E-03 0,04443787 ! cardiac muscle fiber development GO:0048739 10 5 0,000 5,467E-03 0,04428824 ! transepithelial chloride transport GO:0030321 9 5 0,000 5,467E-03 0,04413962 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 5,467E-03 0,043992 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 5,467E-03 0,04384536 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 5,467E-03 0,0436997 ! neutrophil mediated immunity GO:0002446 7 5 0,000 5,467E-03 0,04355499 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 5,467E-03 0,04341125 ! histidine catabolic process GO:0006548 6 5 0,000 5,467E-03 0,04326845 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 5,467E-03 0,04312658 ! microvillus organization GO:0032528 7 5 0,000 5,467E-03 0,04298565 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 5,467E-03 0,04284563 ! L-serine biosynthetic process GO:0006564 6 5 0,000 5,467E-03 0,04270652 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 5,467E-03 0,04256831 ! tryptophan metabolic process GO:0006568 9 5 0,000 5,467E-03 0,04243099 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 5,467E-03 0,04229456 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 5,467E-03 0,042159 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 5,467E-03 0,04202431 ! polyol catabolic process GO:0046174 7 5 0,000 5,467E-03 0,04189047 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 5,467E-03 0,04175749 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 5,467E-03 0,04162534 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 5,467E-03 0,04149403 ! muscle cell migration GO:0014812 8 5 0,000 5,467E-03 0,04136355 ! mitochondrial fission GO:0000266 8 5 0,000 5,467E-03 0,04123388 ! sister chromatid cohesion GO:0007062 12 5 0,000 5,467E-03 0,04110503 ! mRNA transcription GO:0009299 9 5 0,000 5,467E-03 0,04097697 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 5,467E-03 0,04084971 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 5,467E-03 0,04072325 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 5,467E-03 0,04059756 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 5,467E-03 0,04047264 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 5,467E-03 0,04034849 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 5,467E-03 0,0402251 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 5,467E-03 0,04010246 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 5,467E-03 0,03998057 ! positive regulation of transporter activity GO:0032411 8 5 0,000 5,467E-03 0,03985942 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 5,467E-03 0,039739 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 5,467E-03 0,0396193 ! paraxial mesoderm development GO:0048339 14 5 0,000 5,467E-03 0,03950032 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 5,467E-03 0,03938206 ! forebrain neuron development GO:0021884 13 5 0,000 5,467E-03 0,0392645 ! lipoprotein catabolic process GO:0042159 11 5 0,000 5,467E-03 0,03914764 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 5,467E-03 0,03903148 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 5,467E-03 0,038916 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 5,467E-03 0,0388012 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 5,467E-03 0,03868708 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 5,467E-03 0,03857363 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 5,467E-03 0,03846084 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 5,467E-03 0,03834871 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 5,467E-03 0,03823723 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 5,467E-03 0,0381264 ! basic amino acid transport GO:0015802 11 5 0,000 5,467E-03 0,03801621 ! cellular glucose homeostasis GO:0001678 5 5 0,000 5,467E-03 0,03790665 ! early endosome to late endosome transport GO:0045022 12 5 0,000 5,467E-03 0,03779772 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 5,467E-03 0,03768942 ! depyrimidination GO:0045008 10 5 0,000 5,467E-03 0,03758174 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 5,467E-03 0,03747467 ! regulation of centrosome cycle GO:0046605 7 5 0,000 5,467E-03 0,03736821 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 5,467E-03 0,03726235 ! zinc ion homeostasis GO:0055069 8 5 0,000 5,467E-03 0,03715709 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 5,467E-03 0,03705242 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 5,467E-03 0,03694834 ! forebrain morphogenesis GO:0048853 13 5 0,000 5,467E-03 0,03684484 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 5,467E-03 0,03674192 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 5,467E-03 0,03663958 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 5,467E-03 0,0365378 ! peptidyl-arginine modification GO:0018195 9 5 0,000 5,467E-03 0,03643659 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 5,467E-03 0,03633593 ! positive regulation of organ growth GO:0046622 6 5 0,000 5,467E-03 0,03623584 ! response to arsenic GO:0046685 10 5 0,000 5,467E-03 0,03613629 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 5,467E-03 0,03603728 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 5,467E-03 0,03593882 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 5,467E-03 0,03584089 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 5,467E-03 0,0357435 ! response to cadmium ion GO:0046686 7 5 0,000 5,467E-03 0,03564663 ! bile acid biosynthetic process GO:0006699 6 5 0,000 5,467E-03 0,03555029 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 5,467E-03 0,03545447 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 5,467E-03 0,03535916 ! decidualization GO:0046697 11 5 0,000 5,467E-03 0,03526437 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 5,467E-03 0,03517008 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 5,467E-03 0,03507629 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 5,467E-03 0,034983 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 5,467E-03 0,03489021 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 5,467E-03 0,03479791 ! base conversion or substitution editing GO:0016553 5 5 0,000 5,467E-03 0,03470609 ! neural tube patterning GO:0021532 7 5 0,000 5,467E-03 0,03461476 ! embryonic cleavage GO:0040016 6 5 0,000 5,467E-03 0,03452391 ! peroxisome fission GO:0016559 5 5 0,000 5,467E-03 0,03443353 ! histone demethylation GO:0016577 10 5 0,000 5,467E-03 0,03434362 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 5,467E-03 0,03425419 ! mitotic recombination GO:0006312 9 5 0,000 5,467E-03 0,03416522 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 5,467E-03 0,03407671 ! metaphase plate congression GO:0051310 7 5 0,000 5,467E-03 0,03398865 ! regulation of sterol transport GO:0032371 7 5 0,000 5,467E-03 0,03390105 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 5,467E-03 0,0338139 ! enteric nervous system development GO:0048484 8 5 0,000 5,467E-03 0,0337272 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 5,467E-03 0,03364094 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 5,467E-03 0,03355512 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 5,467E-03 0,03346974 ! muscle cell proliferation GO:0033002 11 5 0,000 5,467E-03 0,03338479 ! skeletal muscle regeneration GO:0043403 8 5 0,000 5,467E-03 0,03330027 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 5,467E-03 0,03321618 ! plasminogen activation GO:0031639 5 5 0,000 5,467E-03 0,03313251 ! B cell homeostasis GO:0001782 13 5 0,000 5,467E-03 0,03304927 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 5,467E-03 0,03296644 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 5,467E-03 0,03288402 ! metaphase GO:0051323 8 5 0,000 5,467E-03 0,03280202 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 5,467E-03 0,03272042 ! cellular response to nutrient GO:0031670 8 5 0,000 5,467E-03 0,03263923 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 5,467E-03 0,03255844 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 5,467E-03 0,03247804 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 5,467E-03 0,03239805 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 5,467E-03 0,03231845 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 5,467E-03 0,03223924 ! response to redox state GO:0051775 5 5 0,000 5,467E-03 0,03216041 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 5,467E-03 0,03208197 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 5,467E-03 0,03200391 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 5,467E-03 0,03192623 ! regulation of telomerase activity GO:0051972 6 5 0,000 5,467E-03 0,03184893 ! galactolipid metabolic process GO:0019374 7 5 0,000 5,467E-03 0,031772 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 5,467E-03 0,03169544 ! porphyrin catabolic process GO:0006787 12 5 0,000 5,467E-03 0,03161925 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 5,467E-03 0,03154342 ! striatum development GO:0021756 9 5 0,000 5,467E-03 0,03146796 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 5,467E-03 0,03139286 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 5,467E-03 0,03131811 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 5,467E-03 0,03124372 ! glial cell migration GO:0008347 11 5 0,000 5,467E-03 0,03116969 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 5,467E-03 0,031096 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 5,467E-03 0,03102266 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 5,467E-03 0,03094967 ! somatic stem cell maintenance GO:0035019 15 5 0,000 5,467E-03 0,03087701 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 5,467E-03 0,0308047 ! negative regulation of lipase activity GO:0060192 8 5 0,000 5,467E-03 0,03073273 ! neuroprotection GO:0043526 6 5 0,000 5,467E-03 0,03066109 ! neural plate development GO:0001840 8 5 0,000 5,467E-03 0,03058979 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 5,467E-03 0,03051881 ! regulation of sensory perception GO:0051931 7 5 0,000 5,467E-03 0,03044817 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 5,467E-03 0,03037785 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 5,467E-03 0,03030785 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 5,467E-03 0,03023818 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 5,467E-03 0,03016883 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 5,467E-03 0,03009979 ! sequestering of calcium ion GO:0051208 7 5 0,000 5,467E-03 0,03003107 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 5,467E-03 0,02996266 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 5,467E-03 0,02989456 ! spindle assembly GO:0051225 6 5 0,000 5,467E-03 0,02982678 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 5,467E-03 0,02975929 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 5,467E-03 0,02969212 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 5,467E-03 0,02962524 ! drug metabolic process GO:0017144 6 5 0,000 5,467E-03 0,02955867 ! stem cell division GO:0017145 11 5 0,000 5,467E-03 0,0294924 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 5,467E-03 0,02942642 ! organ regeneration GO:0031100 7 5 0,000 5,467E-03 0,02936073 ! cellular anion homeostasis GO:0030002 9 5 0,000 5,467E-03 0,02929534 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 5,467E-03 0,02923024 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 6,557E-03 0,03497993 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 6,557E-03 0,03490254 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 6,557E-03 0,03482549 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 6,557E-03 0,03474879 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 6,557E-03 0,03467242 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 6,557E-03 0,03459638 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 6,557E-03 0,03452068 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 6,557E-03 0,0344453 ! sleep GO:0030431 13 6 0,000 6,557E-03 0,03437026 ! response to oxygen radical GO:0000305 11 6 0,000 6,557E-03 0,03429554 ! positive regulation of axon extension GO:0045773 11 6 0,000 6,557E-03 0,03422115 ! myoblast cell fate commitment GO:0048625 16 6 0,000 6,557E-03 0,03414708 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 6,557E-03 0,03407332 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 6,557E-03 0,03399989 ! regulation of interferon-beta production GO:0032648 8 6 0,000 6,557E-03 0,03392677 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 6,557E-03 0,03385397 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 6,557E-03 0,03378148 ! forebrain regionalization GO:0021871 8 6 0,000 6,557E-03 0,03370929 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 6,557E-03 0,03363742 ! male meiosis GO:0007140 7 6 0,000 6,557E-03 0,03356585 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 6,557E-03 0,03349458 ! response to zinc ion GO:0010043 9 6 0,000 6,557E-03 0,03342362 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 6,557E-03 0,03335296 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 6,557E-03 0,03328259 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 6,557E-03 0,03321252 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 6,557E-03 0,03314275 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 6,557E-03 0,03307327 ! malate metabolic process GO:0006108 11 6 0,000 6,557E-03 0,03300408 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 6,557E-03 0,03293518 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 6,557E-03 0,03286656 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 6,557E-03 0,03279823 ! opsonization GO:0008228 8 6 0,000 6,557E-03 0,03273018 ! mating behavior GO:0007617 7 6 0,000 6,557E-03 0,03266242 ! neuron remodeling GO:0016322 15 6 0,000 6,557E-03 0,03259494 ! erythrocyte maturation GO:0043249 7 6 0,000 6,557E-03 0,03252773 ! embryonic hemopoiesis GO:0035162 14 6 0,000 6,557E-03 0,0324608 ! equilibrioception GO:0050957 14 6 0,000 6,557E-03 0,03239415 ! protein amino acid dealkylation GO:0008214 12 6 0,000 6,557E-03 0,03232776 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 6,557E-03 0,03226165 ! photoreceptor cell development GO:0042461 10 6 0,000 6,557E-03 0,03219581 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 6,557E-03 0,03213024 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 6,557E-03 0,03206494 ! response to interferon-gamma GO:0034341 15 6 0,000 6,557E-03 0,0319999 ! toxin metabolic process GO:0009404 11 6 0,000 6,557E-03 0,03193512 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 6,557E-03 0,0318706 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 6,557E-03 0,03180635 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 6,557E-03 0,03174235 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 6,557E-03 0,03167861 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 6,557E-03 0,03161513 ! activation of MAPKKK activity GO:0000185 12 6 0,000 6,557E-03 0,0315519 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 6,557E-03 0,03148892 ! thymic T cell selection GO:0045061 12 6 0,000 6,557E-03 0,03142619 ! protein lipoylation GO:0009249 10 6 0,000 6,557E-03 0,03136372 ! cysteine metabolic process GO:0006534 10 6 0,000 6,557E-03 0,03130149 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 6,557E-03 0,0312395 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 6,557E-03 0,03117777 ! glutamate catabolic process GO:0006538 10 6 0,000 6,557E-03 0,03111627 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 6,557E-03 0,03105502 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 6,557E-03 0,03099401 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 6,557E-03 0,03093323 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 6,557E-03 0,0308727 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 6,557E-03 0,0308124 ! hyperosmotic response GO:0006972 9 6 0,000 6,557E-03 0,03075234 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 6,557E-03 0,03069251 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 6,557E-03 0,03063291 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 6,557E-03 0,03057354 ! urea metabolic process GO:0019627 7 6 0,000 6,557E-03 0,03051441 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 6,557E-03 0,0304555 ! neutrophil activation GO:0042119 8 6 0,000 6,557E-03 0,03039682 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 6,557E-03 0,03033836 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 6,557E-03 0,03028013 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 6,557E-03 0,03022212 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 6,557E-03 0,03016434 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 6,557E-03 0,03010677 ! neuron apoptosis GO:0051402 9 6 0,000 6,557E-03 0,03004943 ! nucleoside salvage GO:0043174 9 6 0,000 6,557E-03 0,0299923 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 6,557E-03 0,02993539 ! T cell mediated immunity GO:0002456 16 6 0,000 6,557E-03 0,02987869 ! negative regulation of platelet activation GO:0010544 9 6 0,000 6,557E-03 0,02982221 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 6,557E-03 0,02976594 ! carnitine transport GO:0015879 10 6 0,000 6,557E-03 0,02970989 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 6,557E-03 0,02965404 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 6,557E-03 0,0295984 ! positive regulation of exocytosis GO:0045921 8 6 0,000 6,557E-03 0,02954298 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 6,557E-03 0,02948776 ! 5S class rRNA transcription GO:0042791 11 6 0,000 6,557E-03 0,02943274 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 6,557E-03 0,02937793 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 6,557E-03 0,02932333 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 6,557E-03 0,02926892 ! sodium ion homeostasis GO:0055078 11 6 0,000 6,557E-03 0,02921472 ! establishment of spindle localization GO:0051293 12 6 0,000 6,557E-03 0,02916072 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 6,557E-03 0,02910692 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 6,557E-03 0,02905331 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 6,557E-03 0,02899991 ! neural nucleus development GO:0048857 14 6 0,000 6,557E-03 0,0289467 ! response to UV-C GO:0010225 11 6 0,000 6,557E-03 0,02889368 ! astrocyte development GO:0014002 15 6 0,000 6,557E-03 0,02884086 ! protein targeting to lysosome GO:0006622 10 6 0,000 6,557E-03 0,02878823 ! purine base biosynthetic process GO:0009113 17 6 0,000 6,557E-03 0,02873579 ! interaction with symbiont GO:0051702 13 6 0,000 6,557E-03 0,02868354 ! regulation of dendrite development GO:0050773 16 6 0,000 6,557E-03 0,02863149 ! skeletal muscle contraction GO:0003009 6 6 0,000 6,557E-03 0,02857962 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 6,557E-03 0,02852794 ! response to copper ion GO:0046688 10 6 0,000 6,557E-03 0,02847644 ! response to exogenous dsRNA GO:0043330 10 6 0,000 6,557E-03 0,02842513 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 6,557E-03 0,02837401 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 6,557E-03 0,02832307 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 6,557E-03 0,02827231 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 6,557E-03 0,02822173 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 6,557E-03 0,02817134 ! regulation of dopamine secretion GO:0014059 14 6 0,000 6,557E-03 0,02812112 ! nucleoside catabolic process GO:0009164 7 6 0,000 6,557E-03 0,02807108 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 6,557E-03 0,02802122 ! Schwann cell development GO:0014044 15 6 0,000 6,557E-03 0,02797154 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 6,557E-03 0,02792203 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 6,557E-03 0,0278727 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 6,557E-03 0,02782354 ! subpallium development GO:0021544 10 6 0,000 6,557E-03 0,02777456 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 6,557E-03 0,02772575 ! histone ubiquitination GO:0016574 8 6 0,000 6,557E-03 0,0276771 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 6,557E-03 0,02762863 ! maintenance of organ identity GO:0048496 9 6 0,000 6,557E-03 0,02758033 ! G2 phase GO:0051319 16 6 0,000 6,557E-03 0,0275322 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 6,557E-03 0,02748423 ! establishment of planar polarity GO:0001736 7 6 0,000 6,557E-03 0,02743643 ! regulation of mast cell activation GO:0033003 12 6 0,000 6,557E-03 0,0273888 ! membrane to membrane docking GO:0022614 14 6 0,000 6,557E-03 0,02734133 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 6,557E-03 0,02729403 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 6,557E-03 0,02724689 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 6,557E-03 0,02719991 ! receptor internalization GO:0031623 10 6 0,000 6,557E-03 0,0271531 ! neutrophil homeostasis GO:0001780 10 6 0,000 6,557E-03 0,02710644 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 6,557E-03 0,02705995 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 6,557E-03 0,02701361 ! protein deubiquitination GO:0016579 14 6 0,000 6,557E-03 0,02696743 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 6,557E-03 0,02692141 ! protein destabilization GO:0031648 9 6 0,000 6,557E-03 0,02687555 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 6,557E-03 0,02682985 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 6,557E-03 0,02678429 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 6,557E-03 0,0267389 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 6,557E-03 0,02669365 ! progesterone metabolic process GO:0042448 10 6 0,000 6,557E-03 0,02664856 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 6,557E-03 0,02660362 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 6,557E-03 0,02655884 ! negative regulation of axon extension GO:0030517 21 6 0,000 6,557E-03 0,0265142 ! removal of superoxide radicals GO:0019430 11 6 0,000 6,557E-03 0,02646971 ! triglyceride catabolic process GO:0019433 10 6 0,000 6,557E-03 0,02642538 ! determination of adult lifespan GO:0008340 15 6 0,000 6,557E-03 0,02638119 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 6,557E-03 0,02633714 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 6,557E-03 0,02629325 ! cerebellar cortex formation GO:0021697 8 6 0,000 6,557E-03 0,0262495 ! catecholamine transport GO:0051937 9 6 0,000 6,557E-03 0,0262059 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 6,557E-03 0,02616244 ! sensory cilium assembly GO:0035058 10 6 0,000 6,557E-03 0,02611912 ! organ or tissue specific immune response GO:0002251 7 6 0,000 6,557E-03 0,02607595 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 6,557E-03 0,02603292 ! maternal placenta development GO:0001893 12 6 0,000 6,557E-03 0,02599003 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 6,557E-03 0,02594728 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 6,557E-03 0,02590468 ! negative regulation of B cell activation GO:0050869 13 6 0,000 6,557E-03 0,02586221 ! protein amino acid prenylation GO:0018346 16 6 0,000 6,557E-03 0,02581988 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 6,557E-03 0,02577769 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 6,557E-03 0,02573564 ! positive regulation of coagulation GO:0050820 12 6 0,000 6,557E-03 0,02569373 ! tRNA transcription GO:0009304 14 7 0,000 7,646E-03 0,02991139 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 7,646E-03 0,02986283 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 7,646E-03 0,02981443 ! behavioral response to cocaine GO:0048148 14 7 0,000 7,646E-03 0,02976619 ! regulation of helicase activity GO:0051095 15 7 0,000 7,646E-03 0,0297181 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 7,646E-03 0,02967017 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 7,646E-03 0,02962239 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 7,646E-03 0,02957476 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 7,646E-03 0,02952729 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 7,646E-03 0,02947997 ! prostate gland development GO:0030850 13 7 0,000 7,646E-03 0,02943281 ! nucleotide-sugar transport GO:0015780 12 7 0,000 7,646E-03 0,02938579 ! synaptonemal complex assembly GO:0007130 10 7 0,000 7,646E-03 0,02933892 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 7,646E-03 0,0292922 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 7,646E-03 0,02924563 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 7,646E-03 0,02919921 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 7,646E-03 0,02915294 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 7,646E-03 0,02910681 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 7,646E-03 0,02906083 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 7,646E-03 0,02901499 ! SMAD protein complex assembly GO:0007183 12 7 0,000 7,646E-03 0,0289693 ! glycolipid transport GO:0046836 10 7 0,000 7,646E-03 0,02892375 ! protein amino acid sulfation GO:0006477 10 7 0,000 7,646E-03 0,02887834 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 7,646E-03 0,02883308 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 7,646E-03 0,02878796 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 7,646E-03 0,02874297 ! actin-myosin filament sliding GO:0033275 11 7 0,000 7,646E-03 0,02869813 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 7,646E-03 0,02865343 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 7,646E-03 0,02860887 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 7,646E-03 0,02856445 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 7,646E-03 0,02852016 ! mRNA stabilization GO:0048255 18 7 0,000 7,646E-03 0,02847601 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 7,646E-03 0,028432 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 7,646E-03 0,02838812 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 7,646E-03 0,02834438 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 7,646E-03 0,02830077 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 7,646E-03 0,0282573 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 7,646E-03 0,02821396 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 7,646E-03 0,02817076 ! lipoprotein transport GO:0042953 14 7 0,000 7,646E-03 0,02812768 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 7,646E-03 0,02808474 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 7,646E-03 0,02804193 ! rhythmic behavior GO:0007622 15 7 0,000 7,646E-03 0,02799924 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 7,646E-03 0,02795669 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 7,646E-03 0,02791427 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 7,646E-03 0,02787197 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 7,646E-03 0,02782981 ! regulation of odontogenesis GO:0042481 13 7 0,000 7,646E-03 0,02778777 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 7,646E-03 0,02774586 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 7,646E-03 0,02770407 ! mechanosensory behavior GO:0007638 14 7 0,000 7,646E-03 0,02766241 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 7,646E-03 0,02762088 ! positive regulation of isotype switching GO:0045830 15 7 0,000 7,646E-03 0,02757947 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 7,646E-03 0,02753818 ! protein-cofactor linkage GO:0018065 13 7 0,000 7,646E-03 0,02749702 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 7,646E-03 0,02745598 ! spinal cord patterning GO:0021511 13 7 0,000 7,646E-03 0,02741506 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 7,646E-03 0,02737426 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 7,646E-03 0,02733359 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 7,646E-03 0,02729303 ! adrenal gland development GO:0030325 17 7 0,000 7,646E-03 0,0272526 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 7,646E-03 0,02721228 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 7,646E-03 0,02717209 ! ovulation GO:0030728 9 7 0,000 7,646E-03 0,02713201 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 7,646E-03 0,02709205 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 7,646E-03 0,02705221 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 7,646E-03 0,02701249 ! microtubule nucleation GO:0007020 20 7 0,000 7,646E-03 0,02697288 ! proline biosynthetic process GO:0006561 10 7 0,000 7,646E-03 0,02693339 ! thyroid hormone generation GO:0006590 13 7 0,000 7,646E-03 0,02689401 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 7,646E-03 0,02685475 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 7,646E-03 0,0268156 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 7,646E-03 0,02677657 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 7,646E-03 0,02673765 ! galactose metabolic process GO:0006012 13 7 0,000 7,646E-03 0,02669884 ! vesicle fusion GO:0006906 17 7 0,000 7,646E-03 0,02666015 ! response to dietary excess GO:0002021 8 7 0,000 7,646E-03 0,02662157 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 7,646E-03 0,0265831 ! intracellular pH reduction GO:0051452 11 7 0,000 7,646E-03 0,02654474 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 7,646E-03 0,02650649 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 7,646E-03 0,02646835 ! organ growth GO:0035265 15 7 0,000 7,646E-03 0,02643032 ! purine salvage GO:0043101 10 7 0,000 7,646E-03 0,0263924 ! nucleoside transport GO:0015858 8 7 0,000 7,646E-03 0,02635459 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 7,646E-03 0,02631689 ! parturition GO:0007567 14 7 0,000 7,646E-03 0,02627929 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 7,646E-03 0,0262418 ! rRNA modification GO:0000154 14 7 0,000 7,646E-03 0,02620442 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 7,646E-03 0,02616715 ! spindle checkpoint GO:0031577 15 7 0,000 7,646E-03 0,02612998 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 7,646E-03 0,02609291 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 7,646E-03 0,02605595 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 7,646E-03 0,0260191 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 7,646E-03 0,02598235 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 7,646E-03 0,0259457 ! hyaluronan metabolic process GO:0030212 8 7 0,000 7,646E-03 0,02590916 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 7,646E-03 0,02587272 ! anterograde axon cargo transport GO:0008089 18 7 0,000 7,646E-03 0,02583638 ! fibrinolysis GO:0042730 10 7 0,000 7,646E-03 0,02580014 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 7,646E-03 0,02576401 ! eating behavior GO:0042755 7 7 0,000 7,646E-03 0,02572798 ! B cell lineage commitment GO:0002326 21 7 0,000 7,646E-03 0,02569204 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 7,646E-03 0,02565621 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 7,646E-03 0,02562048 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 7,646E-03 0,02558484 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 7,646E-03 0,02554931 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 7,646E-03 0,02551387 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 7,646E-03 0,02547854 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 7,646E-03 0,0254433 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 7,646E-03 0,02540815 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 7,646E-03 0,02537311 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 7,646E-03 0,02533816 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 7,646E-03 0,02530331 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 7,646E-03 0,02526855 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 7,646E-03 0,02523389 ! regulation of meiosis GO:0040020 12 7 0,000 7,646E-03 0,02519932 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 7,646E-03 0,02516485 ! T cell lineage commitment GO:0002360 16 7 0,000 7,646E-03 0,02513047 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 7,646E-03 0,02509618 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 7,646E-03 0,02506199 ! oxygen homeostasis GO:0032364 12 7 0,000 7,646E-03 0,0250279 ! transcription termination GO:0006353 13 7 0,000 7,646E-03 0,02499389 ! response to tumor cell GO:0002347 13 7 0,000 7,646E-03 0,02495998 ! regulation of respiratory burst GO:0060263 11 7 0,000 7,646E-03 0,02492616 ! coenzyme A metabolic process GO:0015936 12 7 0,000 7,646E-03 0,02489243 ! anaphase GO:0051322 17 7 0,000 7,646E-03 0,02485879 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 7,646E-03 0,02482524 ! axonal fasciculation GO:0007413 18 7 0,000 7,646E-03 0,02479178 ! negative regulation of nuclear division GO:0051784 14 7 0,000 7,646E-03 0,02475842 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 7,646E-03 0,02472514 ! peptidyl-threonine modification GO:0018210 25 7 0,000 7,646E-03 0,02469195 ! diuresis GO:0030146 12 7 0,000 7,646E-03 0,02465885 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 7,646E-03 0,02462584 ! thiamin metabolic process GO:0006772 7 7 0,000 7,646E-03 0,02459292 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 7,646E-03 0,02456008 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 7,646E-03 0,02452734 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 7,646E-03 0,02449468 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 7,646E-03 0,02446211 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 7,646E-03 0,02442962 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 7,646E-03 0,02439722 ! melanin biosynthetic process GO:0042438 8 7 0,000 7,646E-03 0,0243649 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 7,646E-03 0,02433268 ! dopamine biosynthetic process GO:0042416 18 7 0,000 7,646E-03 0,02430053 ! glycolipid catabolic process GO:0019377 15 7 0,000 7,646E-03 0,02426847 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 7,646E-03 0,0242365 ! lymph node development GO:0048535 10 7 0,000 7,646E-03 0,02420461 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 7,646E-03 0,0241728 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 7,646E-03 0,02414108 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 7,646E-03 0,02410944 ! endosome to lysosome transport GO:0008333 11 7 0,000 7,646E-03 0,02407788 ! protein modification by small protein removal GO:0070646 16 7 0,000 7,646E-03 0,02404641 ! adult feeding behavior GO:0008343 9 7 0,000 7,646E-03 0,02401502 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 7,646E-03 0,02398371 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 7,646E-03 0,02395248 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 7,646E-03 0,02392133 ! muscle adaptation GO:0043500 14 7 0,000 7,646E-03 0,02389026 ! embryonic heart tube development GO:0035050 10 7 0,000 7,646E-03 0,02385928 ! retina homeostasis GO:0001895 12 7 0,000 7,646E-03 0,02382837 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 7,646E-03 0,02379755 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 7,646E-03 0,0237668 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 7,646E-03 0,02373613 ! protein prenylation GO:0018342 18 7 0,000 7,646E-03 0,02370555 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 7,646E-03 0,02367504 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 7,646E-03 0,02364461 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 7,646E-03 0,02361425 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 8,733E-03 0,02693881 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 8,733E-03 0,02690432 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 8,733E-03 0,02686991 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 8,733E-03 0,0268356 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 8,733E-03 0,02680137 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 8,733E-03 0,02676723 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 8,733E-03 0,02673317 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 8,733E-03 0,0266992 ! neutral lipid catabolic process GO:0046461 13 8 0,000 8,733E-03 0,02666532 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 8,733E-03 0,02663153 ! meiotic prophase I GO:0007128 13 8 0,000 8,733E-03 0,02659781 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 8,733E-03 0,02656419 ! oligopeptide transport GO:0006857 15 8 0,000 8,733E-03 0,02653065 ! UTP metabolic process GO:0046051 8 8 0,000 8,733E-03 0,02649719 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 8,733E-03 0,02646382 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 8,733E-03 0,02643053 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 8,733E-03 0,02639733 ! macrophage chemotaxis GO:0048246 12 8 0,000 8,733E-03 0,02636421 ! succinate metabolic process GO:0006105 14 8 0,000 8,733E-03 0,02633117 ! membrane hyperpolarization GO:0060081 10 8 0,000 8,733E-03 0,02629821 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 8,733E-03 0,02626534 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 8,733E-03 0,02623255 ! T-helper 1 type immune response GO:0042088 12 8 0,000 8,733E-03 0,02619984 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 8,733E-03 0,02616721 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 8,733E-03 0,02613467 ! ganglioside metabolic process GO:0001573 19 8 0,000 8,733E-03 0,0261022 ! reflex GO:0060004 16 8 0,000 8,733E-03 0,02606982 ! negative regulation of endocytosis GO:0045806 11 8 0,000 8,733E-03 0,02603751 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 8,733E-03 0,02600529 ! endothelial cell differentiation GO:0045446 17 8 0,000 8,733E-03 0,02597314 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 8,733E-03 0,02594108 ! glycerolipid catabolic process GO:0046503 13 8 0,000 8,733E-03 0,02590909 ! hemoglobin metabolic process GO:0020027 13 8 0,000 8,733E-03 0,02587718 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 8,733E-03 0,02584535 ! pigment granule organization GO:0048753 16 8 0,000 8,733E-03 0,0258136 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 8,733E-03 0,02578193 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 8,733E-03 0,02575034 ! astrocyte differentiation GO:0048708 18 8 0,000 8,733E-03 0,02571882 ! histidine metabolic process GO:0006547 16 8 0,000 8,733E-03 0,02568738 GO:0009075|histidine family amino acid metabolic process, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 8,733E-03 0,02565601 ! glycine catabolic process GO:0006546 13 8 0,000 8,733E-03 0,02562472 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 8,733E-03 0,02559351 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 8,733E-03 0,02556238 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 8,733E-03 0,02553132 ! regulation of pigmentation during development GO:0048070 24 8 0,000 8,733E-03 0,02550033 ! melanin metabolic process GO:0006582 15 8 0,000 8,733E-03 0,02546942 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 8,733E-03 0,02543859 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 8,733E-03 0,02540783 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 8,733E-03 0,02537714 ! macrophage activation GO:0042116 12 8 0,000 8,733E-03 0,02534653 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 8,733E-03 0,02531599 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 8,733E-03 0,02528553 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 8,733E-03 0,02525514 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 8,733E-03 0,02522482 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 8,733E-03 0,02519457 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 8,733E-03 0,0251644 ! regulation of vascular permeability GO:0043114 12 8 0,000 8,733E-03 0,0251343 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 8,733E-03 0,02510427 ! osteoblast development GO:0002076 16 8 0,000 8,733E-03 0,02507431 ! positive regulation of vasodilation GO:0045909 13 8 0,000 8,733E-03 0,02504443 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 8,733E-03 0,02501461 ! negative regulation of translational initiation GO:0045947 10 8 0,000 8,733E-03 0,02498487 ! Schwann cell differentiation GO:0014037 19 8 0,000 8,733E-03 0,02495519 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 8,733E-03 0,02492559 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 8,733E-03 0,02489606 ! response to UV-B GO:0010224 16 8 0,000 8,733E-03 0,0248666 ! protein targeting to vacuole GO:0006623 12 8 0,000 8,733E-03 0,0248372 ! protein retention in ER lumen GO:0006621 14 8 0,000 8,733E-03 0,02480788 ! intermediate filament organization GO:0045109 12 8 0,000 8,733E-03 0,02477862 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 8,733E-03 0,02474944 ! cellular extravasation GO:0045123 12 8 0,000 8,733E-03 0,02472032 ! cardiac muscle cell development GO:0055013 13 8 0,000 8,733E-03 0,02469127 ! regulation of circadian rhythm GO:0042752 16 8 0,000 8,733E-03 0,02466229 ! response to antibiotic GO:0046677 11 8 0,000 8,733E-03 0,02463338 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 8,733E-03 0,02460454 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 8,733E-03 0,02457576 ! DNA topological change GO:0006265 12 8 0,000 8,733E-03 0,02454705 ! response to tropane GO:0014073 15 8 0,000 8,733E-03 0,02451841 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 8,733E-03 0,02448983 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 8,733E-03 0,02446132 ! melanosome transport GO:0032402 13 8 0,000 8,733E-03 0,02443288 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 8,733E-03 0,0244045 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 8,733E-03 0,02437619 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 8,733E-03 0,02434794 ! mast cell activation GO:0045576 14 8 0,000 8,733E-03 0,02431976 ! multicellular organismal aging GO:0010259 18 8 0,000 8,733E-03 0,02429165 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 8,733E-03 0,0242636 ! dendrite morphogenesis GO:0048813 13 8 0,000 8,733E-03 0,02423561 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 8,733E-03 0,02420769 ! nucleosome disassembly GO:0006337 14 8 0,000 8,733E-03 0,02417983 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 8,733E-03 0,02415204 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 8,733E-03 0,02412431 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 8,733E-03 0,02409664 ! establishment of chromosome localization GO:0051303 12 8 0,000 8,733E-03 0,02406904 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 8,733E-03 0,0240415 ! intracellular lipid transport GO:0032365 13 8 0,000 8,733E-03 0,02401403 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 8,733E-03 0,02398661 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 8,733E-03 0,02395926 ! regulation of macrophage activation GO:0043030 15 8 0,000 8,733E-03 0,02393197 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 8,733E-03 0,02390475 ! positive regulation of epidermis development GO:0045684 13 8 0,000 8,733E-03 0,02387758 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 8,733E-03 0,02385048 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 8,733E-03 0,02382344 ! hormone catabolic process GO:0042447 17 8 0,000 8,733E-03 0,02379646 ! positive regulation of glucose import GO:0046326 8 8 0,000 8,733E-03 0,02376954 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 8,733E-03 0,02374268 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 8,733E-03 0,02371588 ! ATP catabolic process GO:0006200 11 8 0,000 8,733E-03 0,02368915 ! blastocyst growth GO:0001832 19 8 0,000 8,733E-03 0,02366247 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 8,733E-03 0,02363585 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 8,733E-03 0,0236093 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 8,733E-03 0,0235828 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 8,733E-03 0,02355636 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 8,733E-03 0,02352998 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 8,733E-03 0,02350366 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 8,733E-03 0,0234774 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 8,733E-03 0,0234512 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 8,733E-03 0,02342505 ! amino sugar catabolic process GO:0046348 10 8 0,000 8,733E-03 0,02339897 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 8,733E-03 0,02337294 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 8,733E-03 0,02334697 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 8,733E-03 0,02332106 ! behavioral response to nicotine GO:0035095 12 8 0,000 8,733E-03 0,0232952 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 8,733E-03 0,02326941 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 8,733E-03 0,02324367 ! NAD biosynthetic process GO:0009435 13 8 0,000 8,733E-03 0,02321798 ! regulation of developmental growth GO:0048638 15 9 0,000 9,82E-03 0,02607755 ! axon extension GO:0048675 15 9 0,000 9,82E-03 0,0260488 ! autophagic vacuole formation GO:0000045 15 9 0,000 9,82E-03 0,02602011 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 9,82E-03 0,02599149 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 9,82E-03 0,02596293 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 9,82E-03 0,02593443 ! pentose-phosphate shunt GO:0006098 16 9 0,000 9,82E-03 0,02590599 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 9,82E-03 0,02587761 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 9,82E-03 0,0258493 ! cell proliferation in forebrain GO:0021846 15 9 0,000 9,82E-03 0,02582105 ! phosphate transport GO:0006817 19 9 0,000 9,82E-03 0,02579286 ! reproductive behavior GO:0019098 19 9 0,000 9,82E-03 0,02576474 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 9,82E-03 0,02573667 ! CTP metabolic process GO:0046036 9 9 0,000 9,82E-03 0,02570866 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 9,82E-03 0,02568072 ! GTP metabolic process GO:0046039 9 9 0,000 9,82E-03 0,02565284 ! RNA methylation GO:0001510 15 9 0,000 9,82E-03 0,02562501 ! elastic fiber assembly GO:0048251 15 9 0,000 9,82E-03 0,02559725 ! induction of positive chemotaxis GO:0050930 15 9 0,000 9,82E-03 0,02556955 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 9,82E-03 0,02554191 ! artery development GO:0060840 24 9 0,000 9,82E-03 0,02551432 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 9,82E-03 0,0254868 ! regulation of glycolysis GO:0006110 21 9 0,000 9,82E-03 0,02545933 ! cerebral cortex cell migration GO:0021795 15 9 0,000 9,82E-03 0,02543193 ! keratinocyte proliferation GO:0043616 14 9 0,000 9,82E-03 0,02540458 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 9,82E-03 0,0253773 ! chemosensory behavior GO:0007635 20 9 0,000 9,82E-03 0,02535007 ! middle ear morphogenesis GO:0042474 14 9 0,000 9,82E-03 0,0253229 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 9,82E-03 0,02529578 ! leukocyte degranulation GO:0043299 16 9 0,000 9,82E-03 0,02526873 ! bile acid and bile salt transport GO:0015721 13 9 0,000 9,82E-03 0,02524173 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 9,82E-03 0,02521479 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 9,82E-03 0,02518791 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 9,82E-03 0,02516109 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 9,82E-03 0,02513432 ! protein targeting to ER GO:0045047 22 9 0,000 9,82E-03 0,02510761 ! ceramide biosynthetic process GO:0046513 19 9 0,000 9,82E-03 0,02508096 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 9,82E-03 0,02505436 ! T cell selection GO:0045058 23 9 0,000 9,82E-03 0,02502782 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 9,82E-03 0,02500134 ! phosphagen metabolic process GO:0006599 12 9 0,000 9,82E-03 0,02497491 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 9,82E-03 0,02494853 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 9,82E-03 0,02492222 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 9,82E-03 0,02489596 ! regulation of type I interferon production GO:0032479 12 9 0,000 9,82E-03 0,02486975 ! mannose metabolic process GO:0006013 13 9 0,000 9,82E-03 0,0248436 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 9,82E-03 0,0248175 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 9,82E-03 0,02479146 ! Rac protein signal transduction GO:0016601 17 9 0,000 9,82E-03 0,02476547 ! receptor clustering GO:0043113 18 9 0,000 9,82E-03 0,02473954 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 9,82E-03 0,02471366 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 9,82E-03 0,02468784 ! ruffle organization GO:0031529 15 9 0,000 9,82E-03 0,02466207 ! retinol metabolic process GO:0042572 18 9 0,000 9,82E-03 0,02463635 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 9,82E-03 0,02461069 ! behavioral fear response GO:0001662 22 9 0,000 9,82E-03 0,02458508 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 9,82E-03 0,02455952 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 9,82E-03 0,02453402 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 9,82E-03 0,02450857 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 9,82E-03 0,02448317 ! protein heterooligomerization GO:0051291 16 9 0,000 9,82E-03 0,02445783 ! oligodendrocyte development GO:0014003 10 9 0,000 9,82E-03 0,02443254 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 9,82E-03 0,0244073 ! segment specification GO:0007379 13 9 0,000 9,82E-03 0,02438211 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 9,82E-03 0,02435697 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 9,82E-03 0,02433189 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 9,82E-03 0,02430685 ! response to amine stimulus GO:0014075 13 9 0,000 9,82E-03 0,02428187 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 9,82E-03 0,02425694 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 9,82E-03 0,02423206 ! erythrocyte development GO:0048821 15 9 0,000 9,82E-03 0,02420724 ! gas homeostasis GO:0033483 16 9 0,000 9,82E-03 0,02418246 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 9,82E-03 0,02415773 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 9,82E-03 0,02413306 ! renal water homeostasis GO:0003091 14 9 0,000 9,82E-03 0,02410843 ! postreplication repair GO:0006301 22 9 0,000 9,82E-03 0,02408386 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 9,82E-03 0,02405933 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 9,82E-03 0,02403485 ! icosanoid secretion GO:0032309 15 9 0,000 9,82E-03 0,02401043 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 9,82E-03 0,02398605 ! cerebellum morphogenesis GO:0021587 14 9 0,000 9,82E-03 0,02396173 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 9,82E-03 0,02393745 ! regulation of cell division GO:0051302 15 9 0,000 9,82E-03 0,02391322 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 9,82E-03 0,02388904 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 9,82E-03 0,02386491 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 9,82E-03 0,02384083 ! sterol catabolic process GO:0016127 11 9 0,000 9,82E-03 0,0238168 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 9,82E-03 0,02379281 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 9,82E-03 0,02376888 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 9,82E-03 0,02374499 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 9,82E-03 0,02372115 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 9,82E-03 0,02369735 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 9,82E-03 0,02367361 ! musculoskeletal movement GO:0050881 14 9 0,000 9,82E-03 0,02364991 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 9,82E-03 0,02362626 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 9,82E-03 0,02360266 ! regulation of synaptogenesis GO:0051963 15 9 0,000 9,82E-03 0,0235791 ! purine base metabolic process GO:0006144 21 9 0,000 9,82E-03 0,0235556 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 9,82E-03 0,02353213 ! pigment granule transport GO:0051904 17 9 0,000 9,82E-03 0,02350872 ! regulation of fibrinolysis GO:0051917 16 9 0,000 9,82E-03 0,02348535 ! regulation of telomere maintenance GO:0032204 14 9 0,000 9,82E-03 0,02346203 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 9,82E-03 0,02343875 ! regulation of muscle adaptation GO:0043502 14 9 0,000 9,82E-03 0,02341552 ! regulation of amino acid transport GO:0051955 11 9 0,000 9,82E-03 0,02339234 ! mitochondrion localization GO:0051646 15 9 0,000 9,82E-03 0,0233692 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,01090502 0,02592636 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01090502 0,02590076 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01090502 0,02587522 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,01090502 0,02584973 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01090502 0,02582428 ! synapsis GO:0007129 13 10 0,000 0,01090502 0,02579889 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01090502 0,02577355 ! N-glycan processing GO:0006491 20 10 0,000 0,01090502 0,02574826 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01090502 0,02572301 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01090502 0,02569782 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01090502 0,02567267 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01090502 0,02564758 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01090502 0,02562253 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01090502 0,02559753 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01090502 0,02557259 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01090502 0,02554769 ! androgen metabolic process GO:0008209 17 10 0,000 0,01090502 0,02552283 ! phospholipid efflux GO:0033700 16 10 0,000 0,01090502 0,02549803 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01090502 0,02547327 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01090502 0,02544857 ! lung alveolus development GO:0048286 26 10 0,000 0,01090502 0,02542391 ! pathogenesis GO:0009405 13 10 0,000 0,01090502 0,0253993 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01090502 0,02537473 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01090502 0,02535022 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01090502 0,02532575 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01090502 0,02530132 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01090502 0,02527695 ! endoderm development GO:0007492 16 10 0,000 0,01090502 0,02525262 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01090502 0,02522834 ! arginine catabolic process GO:0006527 13 10 0,000 0,01090502 0,0252041 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01090502 0,02517992 ! proline metabolic process GO:0006560 13 10 0,000 0,01090502 0,02515577 ! L-serine metabolic process GO:0006563 18 10 0,000 0,01090502 0,02513168 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01090502 0,02510763 ! V(D)J recombination GO:0033151 28 10 0,000 0,01090502 0,02508363 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01090502 0,02505967 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01090502 0,02503576 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01090502 0,02501189 ! B cell proliferation GO:0042100 18 10 0,000 0,01090502 0,02498807 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01090502 0,02496429 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01090502 0,02494056 ! multicellular organism growth GO:0035264 18 10 0,000 0,01090502 0,02491688 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01090502 0,02489324 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01090502 0,02486964 ! epithelial cell development GO:0002064 20 10 0,000 0,01090502 0,02484609 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01090502 0,02482259 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01090502 0,02479912 ! macroautophagy GO:0016236 17 10 0,000 0,01090502 0,02477571 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01090502 0,02475233 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01090502 0,024729 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01090502 0,02470572 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01090502 0,02468248 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01090502 0,02465928 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01090502 0,02463613 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01090502 0,02461301 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01090502 0,02458995 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01090502 0,02456692 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01090502 0,02454394 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01090502 0,024521 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01090502 0,02449811 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01090502 0,02447525 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01090502 0,02445244 ! response to dsRNA GO:0043331 20 10 0,000 0,01090502 0,02442968 ! DNA ligation GO:0006266 19 10 0,000 0,01090502 0,02440695 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01090502 0,02438427 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01090502 0,02436163 ! melanosome localization GO:0032400 16 10 0,000 0,01090502 0,02433903 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01090502 0,02431647 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01090502 0,02429396 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01090502 0,02427148 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01090502 0,02424905 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01090502 0,02422666 ! mRNA cleavage GO:0006379 17 10 0,000 0,01090502 0,02420431 ! protein sumoylation GO:0016925 15 10 0,000 0,01090502 0,024182 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01090502 0,02415974 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,01090502 0,02413751 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01090502 0,02411532 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01090502 0,02409318 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01090502 0,02407108 ! salivary gland development GO:0007431 27 10 0,000 0,01090502 0,02404901 ! prophase GO:0051324 15 10 0,000 0,01090502 0,02402699 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01090502 0,02400501 ! apical protein localization GO:0045176 15 10 0,000 0,01090502 0,02398307 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01090502 0,02396116 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01090502 0,0239393 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,01090502 0,02391748 ! midbrain development GO:0030901 13 10 0,000 0,01090502 0,0238957 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01090502 0,02387395 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01090502 0,02385225 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01090502 0,02383058 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01090502 0,02380896 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01090502 0,02378737 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01090502 0,02376583 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01090502 0,02374432 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01090502 0,02372285 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01090502 0,02370142 ! oocyte development GO:0048599 17 10 0,000 0,01090502 0,02368003 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01090502 0,02365868 ! blastocyst formation GO:0001825 17 10 0,000 0,01090502 0,02363736 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01090502 0,02361609 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01090502 0,02359485 ! activation of innate immune response GO:0002218 12 10 0,000 0,01090502 0,02357365 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01090502 0,02355249 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01090502 0,02353137 ! response to nicotine GO:0035094 20 10 0,000 0,01090502 0,02351028 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01090502 0,02348923 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01090502 0,02346822 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01090502 0,02344725 ! localization within membrane GO:0051668 20 10 0,000 0,01090502 0,02342632 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01198916 0,0257323 ! respiratory burst GO:0045730 17 11 0,000 0,01198916 0,02570937 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01198916 0,02568647 ! neuron fate specification GO:0048665 17 11 0,000 0,01198916 0,02566362 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01198916 0,02564081 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01198916 0,02561804 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01198916 0,0255953 ! thyroid gland development GO:0030878 26 11 0,000 0,01198916 0,02557261 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01198916 0,02554996 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01198916 0,02552735 ! response to pain GO:0048265 24 11 0,000 0,01198916 0,02550478 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01198916 0,02548225 ! T cell proliferation GO:0042098 26 11 0,000 0,01198916 0,02545976 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01198916 0,02543731 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01198916 0,0254149 ! bone resorption GO:0045453 16 11 0,000 0,01198916 0,02539253 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,01198916 0,02537019 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01198916 0,0253479 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01198916 0,02532564 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01198916 0,02530343 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01198916 0,02528125 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01198916 0,02525911 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01198916 0,02523702 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01198916 0,02521495 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01198916 0,02519293 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01198916 0,02517095 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01198916 0,025149 ! lipid digestion GO:0044241 18 11 0,000 0,01198916 0,0251271 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01198916 0,02510523 ! UV protection GO:0009650 19 11 0,000 0,01198916 0,0250834 ! adult heart development GO:0007512 14 11 0,000 0,01198916 0,02506161 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01198916 0,02503985 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01198916 0,02501813 ! temperature homeostasis GO:0001659 17 11 0,000 0,01198916 0,02499645 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01198916 0,02497481 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01198916 0,02495321 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01198916 0,02493164 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01198916 0,02491011 ! regulation of organ growth GO:0046620 13 11 0,000 0,01198916 0,02488862 ! pigment granule localization GO:0051875 20 11 0,000 0,01198916 0,02486716 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01198916 0,02484574 ! vasoconstriction GO:0042310 18 11 0,000 0,01198916 0,02482436 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01198916 0,02480302 ! embryonic axis specification GO:0000578 18 11 0,000 0,01198916 0,02478171 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01198916 0,02476044 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01198916 0,0247392 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01198916 0,024718 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01198916 0,02469684 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01198916 0,02467571 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01198916 0,02465462 ! zymogen activation GO:0031638 15 11 0,000 0,01198916 0,02463357 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01198916 0,02461255 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01198916 0,02459157 ! nucleosome positioning GO:0016584 15 11 0,000 0,01198916 0,02457062 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01198916 0,02454971 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01198916 0,02452883 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01198916 0,02450799 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,01198916 0,02448719 ! acid secretion GO:0046717 18 11 0,000 0,01198916 0,02446642 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01198916 0,02444569 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01198916 0,02442499 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01198916 0,02440432 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01198916 0,02438369 ! oocyte differentiation GO:0009994 18 11 0,000 0,01198916 0,0243631 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01198916 0,02434254 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01198916 0,02432201 ! cholesterol efflux GO:0033344 19 11 0,000 0,01198916 0,02430152 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01198916 0,02428107 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01198916 0,02426065 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01198916 0,02424026 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01198916 0,02421991 ! embryonic gut development GO:0048566 15 11 0,000 0,01198916 0,02419959 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01198916 0,0241793 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01198916 0,02415905 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01198916 0,02413884 ! defense response to fungus GO:0050832 13 11 0,000 0,01198916 0,02411865 ! developmental induction GO:0031128 19 11 0,000 0,01198916 0,0240985 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,01198916 0,02407839 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01198916 0,02405831 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01198916 0,02403826 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01198916 0,02401824 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01198916 0,02399826 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01198916 0,02397831 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01198916 0,0239584 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01307214 0,02610089 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01307214 0,02607925 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01307214 0,02605764 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01307214 0,02603607 ! virus-host interaction GO:0019048 29 12 0,000 0,01307214 0,02601453 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,01307214 0,02599303 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01307214 0,02597157 ! cartilage condensation GO:0001502 20 12 0,000 0,01307214 0,02595014 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01307214 0,02592875 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01307214 0,02590739 ! protein complex disassembly GO:0043241 27 12 0,000 0,01307214 0,02588607 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01307214 0,02586478 ! hippocampus development GO:0021766 26 12 0,000 0,01307214 0,02584353 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01307214 0,02582231 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01307214 0,02580112 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01307214 0,02577998 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01307214 0,02575886 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01307214 0,02573778 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01307214 0,02571674 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01307214 0,02569573 ! drug transport GO:0015893 16 12 0,000 0,01307214 0,02567475 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01307214 0,02565381 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01307214 0,0256329 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01307214 0,02561203 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01307214 0,02559119 ! focal adhesion formation GO:0048041 35 12 0,000 0,01307214 0,02557038 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01307214 0,02554961 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01307214 0,02552887 ! forebrain cell migration GO:0021885 21 12 0,000 0,01307214 0,02550817 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01307214 0,0254875 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01307214 0,02546686 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01307214 0,02544626 ! fear response GO:0042596 26 12 0,000 0,01307214 0,02542568 ! monoamine transport GO:0015844 18 12 0,000 0,01307214 0,02540515 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01307214 0,02538464 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01307214 0,02536417 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01307214 0,02534373 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01307214 0,02532333 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01307214 0,02530295 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01307214 0,02528261 ! protein homotetramerization GO:0051289 21 12 0,000 0,01307214 0,02526231 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01307214 0,02524203 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01307214 0,02522179 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01307214 0,02520158 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01307214 0,0251814 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01307214 0,02516126 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01307214 0,02514114 ! cranial nerve development GO:0021545 20 12 0,000 0,01307214 0,02512106 ! fucose catabolic process GO:0019317 22 12 0,000 0,01307214 0,02510101 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01307214 0,025081 ! histone acetylation GO:0016573 26 12 0,000 0,01307214 0,02506101 ! histone methylation GO:0016571 26 12 0,000 0,01307214 0,02504106 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01307214 0,02502114 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01307214 0,02500125 ! gland morphogenesis GO:0022612 29 12 0,000 0,01307214 0,02498139 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01307214 0,02496156 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,01307214 0,02494177 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01307214 0,02492201 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01307214 0,02490227 ! spleen development GO:0048536 22 12 0,000 0,01307214 0,02488257 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01307214 0,0248629 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01307214 0,02484326 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01307214 0,02482366 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01307214 0,02480408 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01307214 0,02478453 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01307214 0,02476502 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01307214 0,02474553 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01307214 0,02472608 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01307214 0,02470665 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01307214 0,02468726 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01415398 0,02670938 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01415398 0,02668845 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01415398 0,02666755 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01415398 0,02664669 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01415398 0,02662585 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01415398 0,02660505 ! lipid localization GO:0010876 28 13 0,000 0,01415398 0,02658428 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01415398 0,02656354 ! organelle fusion GO:0048284 32 13 0,000 0,01415398 0,02654284 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01415398 0,02652217 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01415398 0,02650153 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01415398 0,02648092 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01415398 0,02646035 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01415398 0,0264398 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01415398 0,02641929 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01415398 0,02639881 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01415398 0,02637836 ! methionine metabolic process GO:0006555 27 13 0,000 0,01415398 0,02635794 ! plasma membrane organization GO:0007009 24 13 0,000 0,01415398 0,02633756 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01415398 0,02631721 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01415398 0,02629688 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01415398 0,02627659 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01415398 0,02625633 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01415398 0,02623611 ! response to X-ray GO:0010165 25 13 0,000 0,01415398 0,02621591 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01415398 0,02619574 ! exocrine system development GO:0035272 32 13 0,000 0,01415398 0,02617561 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01415398 0,0261555 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01415398 0,02613543 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01415398 0,02611539 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01415398 0,02609538 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01415398 0,02607539 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01415398 0,02605544 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01415398 0,02603552 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01415398 0,02601563 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01415398 0,02599577 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01415398 0,02597595 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01415398 0,02595615 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01415398 0,02593638 ! ribosome assembly GO:0042255 17 13 0,000 0,01415398 0,02591664 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01415398 0,02589693 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01415398 0,02587725 ! chromatin silencing GO:0006342 26 13 0,000 0,01415398 0,0258576 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01415398 0,02583799 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01415398 0,0258184 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01415398 0,02579884 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01415398 0,02577931 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01415398 0,02575981 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01415398 0,02574034 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01415398 0,02572089 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01415398 0,02570148 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01415398 0,0256821 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01415398 0,02566275 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01415398 0,02564342 ! embryonic placenta development GO:0001892 23 13 0,000 0,01415398 0,02562413 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,01415398 0,02560486 ! insulin secretion GO:0030073 23 13 0,000 0,01415398 0,02558562 ! actin filament polymerization GO:0030041 24 13 0,000 0,01415398 0,02556641 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01415398 0,02554724 ! acrosome reaction GO:0007340 18 13 0,000 0,01415398 0,02552808 ! rRNA transcription GO:0009303 25 14 0,000 0,01523466 0,02745662 ! lactation GO:0007595 26 14 0,000 0,01523466 0,02743607 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,01523466 0,02741555 ! reproductive cellular process GO:0048610 20 14 0,000 0,01523466 0,02739506 ! tRNA modification GO:0006400 20 14 0,000 0,01523466 0,0273746 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,01523466 0,02735417 ! regulation of S phase GO:0033261 23 14 0,000 0,01523466 0,02733377 ! water transport GO:0006833 21 14 0,000 0,01523466 0,02731341 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,01523466 0,02729307 ! non-recombinational repair GO:0000726 25 14 0,000 0,01523466 0,02727276 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,01523466 0,02725248 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,01523466 0,02723224 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,01523466 0,02721202 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,01523466 0,02719183 ! RNA polyadenylation GO:0043631 30 14 0,000 0,01523466 0,02717168 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,01523466 0,02715155 ! palate development GO:0060021 31 14 0,000 0,01523466 0,02713145 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,01523466 0,02711138 ! regulated secretory pathway GO:0045055 23 14 0,000 0,01523466 0,02709135 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,01523466 0,02707134 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,01523466 0,02705136 ! arginine metabolic process GO:0006525 17 14 0,000 0,01523466 0,02703141 ! regulation of heart rate GO:0002027 24 14 0,000 0,01523466 0,02701149 ! organic alcohol transport GO:0015850 29 14 0,000 0,01523466 0,0269916 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,01523466 0,02697174 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,01523466 0,0269519 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,01523466 0,0269321 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01523466 0,02691233 ! neutral amino acid transport GO:0015804 26 14 0,000 0,01523466 0,02689258 ! L-amino acid transport GO:0015807 30 14 0,000 0,01523466 0,02687287 ! bone mineralization GO:0030282 17 14 0,000 0,01523466 0,02685318 ! stem cell development GO:0048864 43 14 0,000 0,01523466 0,02683352 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,01523466 0,02681389 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,01523466 0,02679429 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,01523466 0,02677472 ! cerebellum development GO:0021549 21 14 0,000 0,01523466 0,02675518 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,01523466 0,02673566 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,01523466 0,02671617 ! response to gamma radiation GO:0010332 28 14 0,000 0,01523466 0,02669672 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,01523466 0,02667729 ! cofactor transport GO:0051181 26 14 0,000 0,01523466 0,02665788 ! NADP metabolic process GO:0006739 24 14 0,000 0,01523466 0,02663851 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,01523466 0,02661917 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,01523466 0,02659985 ! intestinal absorption GO:0050892 25 14 0,000 0,01523466 0,02658056 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,01523466 0,0265613 ! oxygen transport GO:0015671 21 14 0,000 0,01523466 0,02654206 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01523466 0,02652286 ! male genitalia development GO:0030539 24 14 0,000 0,01523466 0,02650368 ! regulation of RNA stability GO:0043487 32 14 0,000 0,01523466 0,02648453 ! regulation of axon extension GO:0030516 37 14 0,000 0,01523466 0,02646541 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,01523466 0,02644631 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,01523466 0,02642725 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,01631419 0,02827951 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,01631419 0,02825915 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,01631419 0,02823882 ! superoxide anion generation GO:0042554 20 15 0,000 0,01631419 0,02821851 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,01631419 0,02819824 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,01631419 0,028178 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,01631419 0,02815779 ! copper ion transport GO:0006825 20 15 0,000 0,01631419 0,0281376 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,01631419 0,02811744 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,01631419 0,02809732 ! sulfate transport GO:0008272 23 15 0,000 0,01631419 0,02807722 ! response to cAMP GO:0051591 22 15 0,000 0,01631419 0,02805715 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,01631419 0,02803711 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,01631419 0,0280171 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,01631419 0,02799711 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,01631419 0,02797716 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,01631419 0,02795723 ! response to hexose stimulus GO:0009746 22 15 0,000 0,01631419 0,02793733 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,01631419 0,02791746 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,01631419 0,02789762 ! pituitary gland development GO:0021983 29 15 0,000 0,01631419 0,02787781 ! vesicle coating GO:0006901 33 15 0,000 0,01631419 0,02785802 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,01631419 0,02783826 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,01631419 0,02781854 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,01631419 0,02779883 ! regulation of exocytosis GO:0017157 22 15 0,000 0,01631419 0,02777916 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,01631419 0,02775951 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,01631419 0,0277399 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,01631419 0,02772031 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,01631419 0,02770074 ! regulation of vasodilation GO:0042312 26 15 0,000 0,01631419 0,02768121 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,01631419 0,0276617 ! histone deacetylation GO:0016575 20 15 0,000 0,01631419 0,02764222 ! mRNA splice site selection GO:0006376 38 15 0,000 0,01631419 0,02762277 ! tissue regeneration GO:0042246 26 15 0,000 0,01631419 0,02760334 ! water homeostasis GO:0030104 27 15 0,000 0,01631419 0,02758394 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,01631419 0,02756457 ! muscle maintenance GO:0046716 26 15 0,000 0,01631419 0,02754523 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,01631419 0,02752591 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,01631419 0,02750662 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,01631419 0,02748736 ! dopamine metabolic process GO:0042417 35 15 0,000 0,01631419 0,02746813 ! heme biosynthetic process GO:0006783 29 15 0,000 0,01631419 0,02744892 ! cell killing GO:0001906 29 15 0,000 0,01631419 0,02742974 ! detection of bacterium GO:0016045 18 15 0,000 0,01631419 0,02741058 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,01631419 0,02739145 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,01631419 0,02737235 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,01631419 0,02735328 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,01631419 0,02733423 ! peptide hormone processing GO:0016486 23 15 0,000 0,01631419 0,02731521 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,01739258 0,02910052 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,01739258 0,0290803 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,01739258 0,02906011 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,01739258 0,02903994 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,01739258 0,0290198 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,01739258 0,02899969 ! bone remodeling GO:0046849 27 16 0,000 0,01739258 0,02897961 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,01739258 0,02895955 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,01739258 0,02893953 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,01739258 0,02891953 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,01739258 0,02889955 ! startle response GO:0001964 28 16 0,000 0,01739258 0,02887961 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,01739258 0,02885969 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,01739258 0,0288398 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,01739258 0,02881994 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,01739258 0,02880011 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,01739258 0,0287803 ! protein polyubiquitination GO:0000209 34 16 0,000 0,01739258 0,02876052 ! glutamate metabolic process GO:0006536 22 16 0,000 0,01739258 0,02874077 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,01739258 0,02872104 ! response to osmotic stress GO:0006970 25 16 0,000 0,01739258 0,02870134 ! lysosomal transport GO:0007041 26 16 0,000 0,01739258 0,02868167 ! fructose metabolic process GO:0006000 25 16 0,000 0,01739258 0,02866202 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,01739258 0,02864241 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,01739258 0,02862281 ! intermediate filament-based process GO:0045103 32 16 0,000 0,01739258 0,02860325 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,01739258 0,02858371 ! negative regulation of immune response GO:0050777 35 16 0,000 0,01739258 0,0285642 ! axon cargo transport GO:0008088 43 16 0,000 0,01739258 0,02854472 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,01739258 0,02852526 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,01739258 0,02850583 ! DNA replication initiation GO:0006270 27 16 0,000 0,01739258 0,02848642 ! neuron recognition GO:0008038 35 16 0,000 0,01739258 0,02846704 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,01739258 0,02844769 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,01739258 0,02842837 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,01739258 0,02840907 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,01739258 0,02838979 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,01739258 0,02837055 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,01739258 0,02835132 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,01739258 0,02833213 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,01739258 0,02831296 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,01739258 0,02829382 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,01739258 0,0282747 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,01739258 0,02825561 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,01739258 0,02823654 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,01739258 0,0282175 ! defense response to virus GO:0051607 37 16 0,000 0,01739258 0,02819849 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,01846982 0,02992485 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,01846982 0,02990471 ! metencephalon development GO:0022037 30 17 0,000 0,01846982 0,0298846 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,01846982 0,02986451 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,01846982 0,02984446 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,01846982 0,02982443 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,01846982 0,02980442 ! signal complex assembly GO:0007172 41 17 0,000 0,01846982 0,02978445 ! endothelial cell migration GO:0043542 28 17 0,000 0,01846982 0,0297645 ! inositol metabolic process GO:0006020 28 17 0,000 0,01846982 0,02974458 ! gene silencing by RNA GO:0031047 36 17 0,000 0,01846982 0,02972468 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,01846982 0,02970481 ! glial cell development GO:0021782 27 17 0,000 0,01846982 0,02968497 ! limbic system development GO:0021761 36 17 0,000 0,01846982 0,02966515 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,01846982 0,02964536 ! adult walking behavior GO:0007628 33 17 0,000 0,01846982 0,0296256 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,01846982 0,02960586 ! heart looping GO:0001947 30 17 0,000 0,01846982 0,02958615 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,01846982 0,02956647 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,01846982 0,02954681 ! myoblast differentiation GO:0045445 45 17 0,000 0,01846982 0,02952717 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,01846982 0,02950757 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,01846982 0,02948799 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,01846982 0,02946843 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,01846982 0,0294489 ! glycine metabolic process GO:0006544 28 17 0,000 0,01846982 0,0294294 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,01846982 0,02940993 ! NAD metabolic process GO:0019674 29 17 0,000 0,01846982 0,02939047 ! membrane budding GO:0006900 37 17 0,000 0,01846982 0,02937105 ! DNA integration GO:0015074 29 17 0,000 0,01846982 0,02935165 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,01846982 0,02933228 ! regulation of protein binding GO:0043393 33 17 0,000 0,01846982 0,02931293 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,01846982 0,0292936 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,01846982 0,02927431 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,01846982 0,02925503 ! genitalia development GO:0048806 30 17 0,000 0,01846982 0,02923579 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,01846982 0,02921657 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,01846982 0,02919737 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,01846982 0,0291782 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,01846982 0,02915905 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,01846982 0,02913993 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,01846982 0,02912084 ! steroid catabolic process GO:0006706 31 17 0,000 0,01846982 0,02910177 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,01846982 0,02908272 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,01846982 0,0290637 ! gas transport GO:0015669 25 17 0,000 0,01846982 0,0290447 ! organic cation transport GO:0015695 31 17 0,000 0,01846982 0,02902573 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,01846982 0,02900679 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,01846982 0,02898787 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,01846982 0,02896897 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,01846982 0,0289501 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,01954592 0,03061685 ! neuron maturation GO:0042551 42 18 0,000 0,01954592 0,03059693 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,01954592 0,03057704 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,01954592 0,03055717 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,01954592 0,03053733 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,01954592 0,03051751 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,01954592 0,03049772 ! memory GO:0007613 31 18 0,000 0,01954592 0,03047796 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,01954592 0,03045822 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,01954592 0,0304385 ! patterning of blood vessels GO:0001569 39 18 0,000 0,01954592 0,03041881 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,01954592 0,03039915 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,01954592 0,03037951 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,01954592 0,0303599 ! glutamine metabolic process GO:0006541 29 18 0,000 0,01954592 0,03034031 ! response to retinoic acid GO:0032526 26 18 0,000 0,01954592 0,03032075 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,01954592 0,03030121 ! response to fungus GO:0009620 21 18 0,000 0,01954592 0,0302817 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,01954592 0,03026222 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,01954592 0,03024276 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,01954592 0,03022332 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,01954592 0,03020391 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,01954592 0,03018452 ! vitamin transport GO:0051180 27 18 0,000 0,01954592 0,03016516 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,01954592 0,03014582 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,01954592 0,03012651 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,01954592 0,03010722 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,01954592 0,03008796 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,01954592 0,03006872 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,01954592 0,03004951 ! nerve development GO:0021675 28 18 0,000 0,01954592 0,03003032 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,01954592 0,03001116 ! protein secretion GO:0009306 39 19 0,000 0,02062087 0,03164147 ! positive regulation of translation GO:0045727 30 19 0,000 0,02062087 0,0316213 ! negative regulation of defense response GO:0031348 25 19 0,000 0,02062087 0,03160116 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,02062087 0,03158104 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,02062087 0,03156095 ! skin development GO:0043588 36 19 0,000 0,02062087 0,03154089 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,02062087 0,03152085 ! lipid phosphorylation GO:0046834 35 19 0,000 0,02062087 0,03150084 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02062087 0,03148085 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,02062087 0,03146089 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,02062087 0,03144095 ! bile acid metabolic process GO:0008206 29 19 0,000 0,02062087 0,03142104 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,02062087 0,03140115 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,02062087 0,03138129 ! cerebral cortex development GO:0021987 36 19 0,000 0,02062087 0,03136145 ! pigmentation during development GO:0048066 41 19 0,000 0,02062087 0,03134164 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,02062087 0,03132186 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,02062087 0,03130209 ! heme metabolic process GO:0042168 36 19 0,000 0,02062087 0,03128236 ! actin filament bundle formation GO:0051017 42 19 0,000 0,02062087 0,03126265 ! neuromuscular junction development GO:0007528 34 19 0,000 0,02062087 0,03124296 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,02062087 0,0312233 ! plasma membrane fusion GO:0045026 28 19 0,000 0,02062087 0,03120366 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,02062087 0,03118405 ! peptide cross-linking GO:0018149 37 19 0,000 0,02062087 0,03116446 ! protein export from nucleus GO:0006611 36 19 0,000 0,02062087 0,0311449 ! heart process GO:0003015 30 19 0,000 0,02062087 0,03112536 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,02062087 0,03110584 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,02062087 0,03108635 ! visual learning GO:0008542 36 19 0,000 0,02062087 0,03106689 ! cellular pigmentation GO:0033059 36 19 0,000 0,02062087 0,03104745 ! G1 phase GO:0051318 40 19 0,000 0,02062087 0,03102803 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,02062087 0,03100864 ! cell-cell junction organization GO:0045216 35 19 0,000 0,02062087 0,03098927 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,02062087 0,03096992 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,02062087 0,0309506 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,02062087 0,03093131 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,02062087 0,03091204 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,02062087 0,03089279 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,02062087 0,03087357 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,02062087 0,03085437 ! cilium assembly GO:0042384 37 19 0,000 0,02062087 0,03083519 ! peptide hormone secretion GO:0030072 31 19 0,000 0,02062087 0,03081604 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,02169468 0,03240062 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,02169468 0,03238052 ! positive regulation of ossification GO:0045778 47 20 0,000 0,02169468 0,03236045 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,02169468 0,0323404 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,02169468 0,03232037 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,02169468 0,03230037 ! cAMP metabolic process GO:0046058 36 20 0,000 0,02169468 0,0322804 ! response to vitamin GO:0033273 31 20 0,000 0,02169468 0,03226045 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,02169468 0,03224052 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,02169468 0,03222062 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,02169468 0,03220074 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,02169468 0,03218089 ! response to alkaloid GO:0043279 38 20 0,000 0,02169468 0,03216106 ! retinoid metabolic process GO:0001523 32 20 0,000 0,02169468 0,03214126 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,02169468 0,03212148 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,02169468 0,03210172 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,02169468 0,03208199 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,02169468 0,03206229 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,02169468 0,03204261 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,02169468 0,03202295 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,02169468 0,03200331 ! body fluid secretion GO:0007589 31 20 0,000 0,02169468 0,0319837 ! peptide secretion GO:0002790 35 20 0,000 0,02169468 0,03196412 ! stem cell differentiation GO:0048863 53 20 0,000 0,02169468 0,03194456 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,02169468 0,03192502 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,02169468 0,0319055 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,02169468 0,03188601 ! sensory perception of pain GO:0019233 30 20 0,000 0,02169468 0,03186655 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,02169468 0,0318471 ! diencephalon development GO:0021536 34 20 0,000 0,02169468 0,03182769 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,02169468 0,03180829 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,02169468 0,03178892 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,02169468 0,03176957 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,02169468 0,03175025 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,02169468 0,03173095 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,02169468 0,03171167 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,02169468 0,03169241 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,02169468 0,03167318 ! regulation of glucose import GO:0046324 29 20 0,000 0,02169468 0,03165397 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,02169468 0,03163479 ! actin filament-based movement GO:0030048 43 20 0,000 0,02169468 0,03161563 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,02169468 0,03159649 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,02169468 0,03157738 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,02169468 0,03155829 ! negative regulation of translation GO:0017148 29 20 0,000 0,02169468 0,03153922 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,02169468 0,03152017 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,02169468 0,03150115 ! regulation of cell killing GO:0031341 42 21 0,000 0,02276735 0,03303875 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,02276735 0,03301883 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,02276735 0,03299894 ! hormone secretion GO:0046879 38 21 0,000 0,02276735 0,03297907 ! glycerol metabolic process GO:0006071 34 21 0,000 0,02276735 0,03295923 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,02276735 0,03293941 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,02276735 0,03291962 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,02276735 0,03289985 ! axis specification GO:0009798 38 21 0,000 0,02276735 0,0328801 ! ovarian follicle development GO:0001541 35 21 0,000 0,02276735 0,03286037 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,02276735 0,03284067 ! smooth muscle contraction GO:0006939 46 21 0,000 0,02276735 0,032821 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,02276735 0,03280134 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,02276735 0,03278171 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,02276735 0,03276211 ! cell aging GO:0007569 44 21 0,000 0,02276735 0,03274252 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,02276735 0,03272296 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,02276735 0,03270343 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,02276735 0,03268392 ! cytolysis GO:0019835 24 21 0,000 0,02276735 0,03266443 ! vasodilation GO:0042311 39 21 0,000 0,02276735 0,03264496 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,02276735 0,03262552 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,02276735 0,0326061 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,02276735 0,0325867 ! oogenesis GO:0048477 36 21 0,000 0,02276735 0,03256733 ! DNA modification GO:0006304 34 21 0,000 0,02276735 0,03254798 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,02276735 0,03252865 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,02276735 0,03250934 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,02276735 0,03249006 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,02276735 0,0324708 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,02276735 0,03245157 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,02276735 0,03243235 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,02276735 0,03241316 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,02276735 0,03239399 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,02276735 0,03237485 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,02276735 0,03235573 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,02276735 0,03233663 ! sperm-egg recognition GO:0035036 21 21 0,000 0,02276735 0,03231755 ! gut development GO:0048565 39 21 0,000 0,02276735 0,03229849 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,02383888 0,03379867 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,02383888 0,03377876 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,02383888 0,03375888 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,02383888 0,03373902 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,02383888 0,03371919 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,02383888 0,03369938 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,02383888 0,03367959 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,02383888 0,03365982 ! regeneration GO:0031099 41 22 0,000 0,02383888 0,03364008 ! keratinization GO:0031424 28 22 0,000 0,02383888 0,03362036 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,02383888 0,03360067 ! sensory perception of taste GO:0050909 28 22 0,000 0,02383888 0,03358099 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,02383888 0,03356134 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,02383888 0,03354172 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,02383888 0,03352211 ! vacuolar transport GO:0007034 36 22 0,000 0,02383888 0,03350253 ! lysosome organization GO:0007040 41 22 0,000 0,02383888 0,03348298 ! central nervous system neuron development GO:0021954 46 22 0,000 0,02383888 0,03346344 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,02383888 0,03344393 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,02383888 0,03342444 ! fucose metabolic process GO:0006004 39 22 0,000 0,02383888 0,03340497 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,02383888 0,03338553 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,02383888 0,03336611 ! ureteric bud development GO:0001657 43 22 0,000 0,02383888 0,03334671 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,02383888 0,03332733 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,02383888 0,03330798 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,02383888 0,03328865 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,02383888 0,03326934 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,02383888 0,03325005 ! sarcomere organization GO:0045214 30 22 0,000 0,02383888 0,03323079 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,02383888 0,03321154 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,02383888 0,03319232 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,02383888 0,03317313 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,02383888 0,03315395 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,02383888 0,0331348 ! protein stabilization GO:0050821 39 22 0,000 0,02383888 0,03311567 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,02490926 0,03458263 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,02490926 0,03456268 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,02490926 0,03454276 ! gluconeogenesis GO:0006094 33 23 0,000 0,02490926 0,03452286 ! viral genome replication GO:0019079 41 23 0,000 0,02490926 0,03450299 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,02490926 0,03448314 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,02490926 0,03446331 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,02490926 0,0344435 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,02490926 0,03442372 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,02490926 0,03440395 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,02490926 0,03438422 ! visual behavior GO:0007632 42 23 0,000 0,02490926 0,0343645 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,02490926 0,03434481 ! response to ethanol GO:0045471 46 23 0,000 0,02490926 0,03432514 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,02490926 0,03430549 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,02490926 0,03428586 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,02490926 0,03426626 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,02490926 0,03424668 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,02490926 0,03422712 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,02490926 0,03420759 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,02490926 0,03418807 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,02490926 0,03416858 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,02490926 0,03414911 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,02490926 0,03412966 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,02490926 0,03411024 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,02490926 0,03409084 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,02490926 0,03407146 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,02490926 0,0340521 ! fatty acid transport GO:0015908 44 23 0,000 0,02490926 0,03403276 ! platelet activation GO:0030168 37 23 0,000 0,02490926 0,03401344 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,02490926 0,03399415 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,02490926 0,03397488 ! hormone transport GO:0009914 40 23 0,000 0,02490926 0,03395563 ! cell-cell recognition GO:0009988 25 23 0,000 0,02490926 0,0339364 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,02490926 0,0339172 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,02490926 0,03389801 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,02490926 0,03387885 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,02490926 0,03385971 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,02597851 0,03529323 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,02597851 0,03527331 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,02597851 0,03525341 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,02597851 0,03523354 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,02597851 0,03521369 ! vesicle docking GO:0048278 47 24 0,000 0,02597851 0,03519386 ! spinal cord development GO:0021510 47 24 0,000 0,02597851 0,03517406 ! vacuole organization GO:0007033 43 24 0,000 0,02597851 0,03515428 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,02597851 0,03513452 ! digestive system process GO:0022600 39 24 0,000 0,02597851 0,03511478 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,02597851 0,03509506 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,02597851 0,03507537 ! regulation of behavior GO:0050795 43 24 0,000 0,02597851 0,03505569 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,02597851 0,03503604 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,02597851 0,03501642 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,02597851 0,03499681 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,02597851 0,03497723 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,02597851 0,03495766 ! membrane depolarization GO:0051899 39 24 0,000 0,02597851 0,03493812 ! pallium development GO:0021543 49 24 0,000 0,02597851 0,03491861 ! pentose metabolic process GO:0019321 35 24 0,000 0,02597851 0,03489911 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,02597851 0,03487963 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,02597851 0,03486018 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,02597851 0,03484075 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,02597851 0,03482134 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,02597851 0,03480195 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,02597851 0,03478258 ! regulation of amine transport GO:0051952 40 24 0,000 0,02597851 0,03476324 ! protein tetramerization GO:0051262 52 24 0,000 0,02597851 0,03474392 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,02704663 0,03615232 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,02704663 0,03613225 ! myelination GO:0042552 45 25 0,000 0,02704663 0,0361122 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,02704663 0,03609217 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,02704663 0,03607216 ! phototransduction GO:0007602 33 25 0,000 0,02704663 0,03605218 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,02704663 0,03603222 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,02704663 0,03601228 ! sperm motility GO:0030317 31 25 0,000 0,02704663 0,03599236 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,02704663 0,03597246 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,02704663 0,03595259 ! receptor metabolic process GO:0043112 46 25 0,000 0,02704663 0,03593273 ! chromosome condensation GO:0030261 45 25 0,000 0,02704663 0,0359129 ! osteoblast differentiation GO:0001649 60 25 0,000 0,02704663 0,0358931 ! neural crest cell development GO:0014032 54 25 0,000 0,02704663 0,03587331 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 0,000 0,02704663 0,03585354 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,02704663 0,0358338 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,02704663 0,03581408 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,02704663 0,03579438 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,02704663 0,0357747 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,02704663 0,03575505 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,02704663 0,03573541 ! immunoglobulin production GO:0002377 55 25 0,000 0,02704663 0,0357158 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,02704663 0,03569621 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,02704663 0,03567664 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,02704663 0,03565709 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,02704663 0,03563756 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,02704663 0,03561805 ! telomere organization GO:0032200 43 25 0,000 0,02704663 0,03559857 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,02704663 0,0355791 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,0281136 0,03696247 ! embryonic pattern specification GO:0009880 44 26 0,000 0,0281136 0,03694229 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,0281136 0,03692212 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,0281136 0,03690198 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,0281136 0,03688186 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,0281136 0,03686176 ! tube lumen formation GO:0035148 50 26 0,000 0,0281136 0,03684168 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,0281136 0,03682163 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,0281136 0,03680159 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,0281136 0,03678158 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,0281136 0,03676159 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,0281136 0,03674162 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,0281136 0,03672168 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,0281136 0,03670175 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,0281136 0,03668185 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,0281136 0,03666197 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,0281136 0,03664211 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,0281136 0,03662227 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,0281136 0,03660245 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,0281136 0,03658265 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,0281136 0,03656288 ! blastocyst development GO:0001824 49 26 0,000 0,0281136 0,03654313 ! leukocyte proliferation GO:0070661 52 26 0,000 0,0281136 0,0365234 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,0281136 0,03650369 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,0281136 0,036484 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,02917944 0,03784676 ! neuron fate commitment GO:0048663 48 27 0,000 0,02917944 0,03782637 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,02917944 0,037806 ! iron ion transport GO:0006826 59 27 0,000 0,02917944 0,03778565 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,02917944 0,03776533 ! protein amino acid acylation GO:0043543 55 27 0,000 0,02917944 0,03774502 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,02917944 0,03772474 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,02917944 0,03770448 ! fat cell differentiation GO:0045444 50 27 0,000 0,02917944 0,03768424 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,02917944 0,03766403 ! autophagy GO:0006914 41 27 0,000 0,02917944 0,03764383 ! male gonad development GO:0008584 44 27 0,000 0,02917944 0,03762366 ! response to toxin GO:0009636 47 27 0,000 0,02917944 0,03760351 ! primary neural tube formation GO:0014020 51 27 0,000 0,02917944 0,03758337 ! base-excision repair GO:0006284 41 27 0,000 0,02917944 0,03756327 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,02917944 0,03754318 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,02917944 0,03752311 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,02917944 0,03750307 ! glutathione metabolic process GO:0006749 39 27 0,000 0,02917944 0,03748305 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,02917944 0,03746304 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,02917944 0,03744306 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,02917944 0,0374231 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,02917944 0,03740317 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,03024415 0,0387473 ! circadian rhythm GO:0007623 50 28 0,000 0,03024415 0,03872668 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,03024415 0,03870608 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,03024415 0,0386855 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,03024415 0,03866495 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,03024415 0,03864441 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,03024415 0,0386239 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,03024415 0,03860341 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,03024415 0,03858294 ! synaptogenesis GO:0007416 42 28 0,000 0,03024415 0,0385625 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,03024415 0,03854207 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,03024415 0,03852167 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,03024415 0,03850129 ! translational initiation GO:0006413 65 29 0,000 0,03130773 0,03983416 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,03130773 0,03981311 ! regulation of pH GO:0006885 43 29 0,000 0,03130773 0,03979207 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,03130773 0,03977106 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,03130773 0,03975008 ! catechol metabolic process GO:0009712 54 29 0,000 0,03130773 0,03972911 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,03130773 0,03970817 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,03130773 0,03968725 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,03130773 0,03966635 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,03130773 0,03964547 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,03130773 0,03962462 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,03130773 0,03960378 ! cell fate determination GO:0001709 60 29 0,000 0,03130773 0,03958297 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,03130773 0,03956218 ! detection of light stimulus GO:0009583 38 29 0,000 0,03130773 0,03954142 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,03130773 0,03952067 ! tissue homeostasis GO:0001894 48 29 0,000 0,03130773 0,03949995 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,03130773 0,03947924 ! phenol metabolic process GO:0018958 55 30 0,000 0,03237017 0,04079761 ! zinc ion transport GO:0006829 45 30 0,000 0,03237017 0,04077625 ! membrane docking GO:0022406 61 30 0,000 0,03237017 0,04075491 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,03237017 0,0407336 ! cell junction assembly GO:0034329 78 30 0,000 0,03237017 0,04071231 ! regulation of innate immune response GO:0045088 51 30 0,000 0,03237017 0,04069103 ! acute-phase response GO:0006953 49 30 0,000 0,03237017 0,04066979 ! myofibril assembly GO:0030239 47 30 0,000 0,03237017 0,04064856 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,03237017 0,04062736 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,03237017 0,04060617 ! phospholipid transport GO:0015914 51 30 0,000 0,03237017 0,04058501 ! ensheathment of neurons GO:0007272 57 30 0,000 0,03237017 0,04056387 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,03237017 0,04054276 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,03237017 0,04052166 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,03237017 0,04050059 ! eye morphogenesis GO:0048592 60 30 0,000 0,03237017 0,04047954 ! regulation of B cell activation GO:0050864 50 30 0,000 0,03237017 0,04045851 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,03343149 0,04176332 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,03343149 0,04174165 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,03343149 0,04172 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,03343149 0,04169837 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,03343149 0,04167677 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,03343149 0,04165519 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,03343149 0,04163363 ! ovulation cycle process GO:0022602 49 31 0,000 0,03343149 0,04161209 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,03343149 0,04159057 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,03343149 0,04156908 ! peptide transport GO:0015833 55 31 0,000 0,03343149 0,04154761 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,03343149 0,04152616 ! iron ion homeostasis GO:0055072 54 31 0,000 0,03343149 0,04150473 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,03343149 0,04148332 ! mesoderm formation GO:0001707 69 31 0,000 0,03343149 0,04146194 ! natural killer cell activation GO:0030101 45 31 0,000 0,03343149 0,04144058 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,03343149 0,04141924 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,03343149 0,04139792 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,03343149 0,04137663 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,03343149 0,04135535 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,03449168 0,0426449 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,03449168 0,042623 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,03449168 0,04260111 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,03449168 0,04257926 ! cholesterol transport GO:0030301 56 32 0,000 0,03449168 0,04255742 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,03449168 0,04253561 ! spliceosome assembly GO:0000245 67 32 0,000 0,03449168 0,04251382 ! spindle organization GO:0007051 46 32 0,000 0,03449168 0,04249205 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,03449168 0,0424703 ! metanephros development GO:0001656 74 32 0,000 0,03449168 0,04244858 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,03449168 0,04242688 ! response to ionizing radiation GO:0010212 65 32 0,000 0,03449168 0,0424052 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,03449168 0,04238354 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,03449168 0,0423619 ! muscle cell development GO:0055001 49 32 0,000 0,03449168 0,04234029 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,03449168 0,0423187 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,03449168 0,04229713 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,03449168 0,04227558 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,03449168 0,04225406 ! ovulation cycle GO:0042698 51 32 0,000 0,03449168 0,04223256 ! peripheral nervous system development GO:0007422 64 32 0,000 0,03449168 0,04221107 ! BMP signaling pathway GO:0030509 64 32 0,000 0,03449168 0,04218961 ! hindbrain development GO:0030902 61 32 0,000 0,03449168 0,04216818 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,03449168 0,04214676 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,03449168 0,04212537 ! gene silencing GO:0016458 65 32 0,000 0,03449168 0,04210399 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,03555073 0,04337478 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,03555073 0,0433528 ! protein targeting to membrane GO:0006612 68 33 0,000 0,03555073 0,04333083 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,03555073 0,04330889 ! ceramide metabolic process GO:0006672 64 33 0,000 0,03555073 0,04328698 ! formation of primary germ layer GO:0001704 72 33 0,000 0,03555073 0,04326508 ! cell fate specification GO:0001708 52 33 0,000 0,03555073 0,04324321 ! sterol transport GO:0015918 57 33 0,000 0,03555073 0,04322136 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,03555073 0,04319953 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,03555073 0,04317772 ! adult locomotory behavior GO:0008344 59 33 0,000 0,03555073 0,04315594 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,03555073 0,04313417 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,03555073 0,04311243 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,03660867 0,04437302 ! glial cell differentiation GO:0010001 63 34 0,000 0,03660867 0,04435068 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,03660867 0,04432836 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,03660867 0,04430606 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,03660867 0,04428379 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,03660867 0,04426153 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,03660867 0,0442393 ! mismatch repair GO:0006298 46 34 0,000 0,03660867 0,04421709 ! spermatid development GO:0007286 63 34 0,000 0,03660867 0,04419491 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,03660867 0,04417274 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,03660867 0,0441506 ! regulation of muscle development GO:0048634 70 35 0,000 0,03766547 0,04540237 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,03766547 0,04537963 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,03766547 0,04535692 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,03766547 0,04533423 ! odontogenesis GO:0042476 66 35 0,000 0,03766547 0,04531156 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,03766547 0,04528892 ! female gonad development GO:0008585 58 35 0,000 0,03766547 0,0452663 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,03766547 0,0452437 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,03766547 0,04522112 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,03766547 0,04519857 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,03766547 0,04517604 ! cytokine production GO:0001816 59 35 0,000 0,03766547 0,04515353 ! neural tube formation GO:0001841 67 35 0,000 0,03766547 0,04513104 ! vesicle localization GO:0051648 64 35 0,000 0,03766547 0,04510858 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,03872116 0,0463498 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,03872116 0,04632675 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,03872116 0,04630373 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,03872116 0,04628072 ! cell junction organization GO:0034330 86 36 0,000 0,03872116 0,04625775 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,03872116 0,04623479 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,03872116 0,04621185 ! positive regulation of cell development GO:0010720 80 36 0,000 0,03872116 0,04618894 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,03872116 0,04616606 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,03872116 0,04614319 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,03872116 0,04612035 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,03872116 0,04609753 ! embryonic organ development GO:0048568 57 36 0,000 0,03872116 0,04607473 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,03872116 0,04605195 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,03872116 0,0460292 ! RNA export from nucleus GO:0006405 56 37 0,000 0,03977571 0,04725944 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,03977571 0,04723612 ! meiosis I GO:0007127 65 37 0,000 0,03977571 0,04721281 ! sister chromatid segregation GO:0000819 58 37 0,000 0,03977571 0,04718953 ! actomyosin structure organization GO:0031032 62 37 0,000 0,03977571 0,04716627 ! organic anion transport GO:0015711 68 37 0,000 0,03977571 0,04714304 ! tissue remodeling GO:0048771 76 37 0,000 0,03977571 0,04711983 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,03977571 0,04709664 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,03977571 0,04707347 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,03977571 0,04705033 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,03977571 0,04702721 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,03977571 0,04700411 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,03977571 0,04698104 ! pigment metabolic process GO:0042440 80 37 0,000 0,03977571 0,04695798 ! spermatid differentiation GO:0048515 66 37 0,000 0,03977571 0,04693495 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,04082915 0,04815438 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,04082915 0,04813079 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,04082915 0,04810722 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,04082915 0,04808367 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,04082915 0,04806015 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,04082915 0,04803665 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,04082915 0,04801317 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,04082915 0,04798971 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,04082915 0,04796628 ! lipid homeostasis GO:0055088 67 38 0,000 0,04082915 0,04794287 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,04082915 0,04791948 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,04082915 0,04789612 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,04082915 0,04787278 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,04082915 0,04784946 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,04082915 0,04782616 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,04082915 0,04780289 ! mRNA catabolic process GO:0006402 71 39 0,000 0,04188147 0,0490111 ! mammary gland development GO:0030879 86 39 0,000 0,04188147 0,04898727 ! learning GO:0007612 77 39 0,000 0,04188147 0,04896347 ! ear morphogenesis GO:0042471 60 39 0,000 0,04188147 0,04893969 ! organic ether metabolic process GO:0018904 55 39 0,000 0,04188147 0,04891593 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,04188147 0,0488922 ! segmentation GO:0035282 67 39 0,000 0,04188147 0,04886848 ! ion transmembrane transport GO:0034220 66 39 0,000 0,04188147 0,0488448 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,04188147 0,04882113 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,04188147 0,04879749 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,04188147 0,04877387 ! RNA modification GO:0009451 57 39 0,000 0,04188147 0,04875027 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,04188147 0,0487267 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,04293267 0,04992557 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,04293267 0,04990145 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,04293267 0,04987735 ! feeding behavior GO:0007631 59 40 0,000 0,04293267 0,04985328 ! negative regulation of binding GO:0051100 72 40 0,000 0,04293267 0,04982923 ! mesenchymal cell development GO:0014031 87 40 0,000 0,04293267 0,0498052 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,04293267 0,0497812 ! maintenance of protein location GO:0045185 91 40 0,000 0,04293267 0,04975722 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,04398275 0,05094968 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,04398275 0,05092516 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,04398275 0,05090067 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,04398275 0,05087619 ! gliogenesis GO:0042063 88 41 0,000 0,04398275 0,05085175 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,04398275 0,05082732 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,04398275 0,05080292 ! T cell differentiation GO:0030217 81 41 0,000 0,04398275 0,05077854 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,04398275 0,05075419 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,04398275 0,05072986 ! female gamete generation GO:0007292 61 41 0,000 0,04398275 0,05070555 ! polyol metabolic process GO:0019751 66 41 0,000 0,04398275 0,05068127 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,04398275 0,05065701 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,04503171 0,05184033 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,04503171 0,05181554 ! regulation of tube size GO:0035150 71 42 0,000 0,04503171 0,05179077 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,04503171 0,05176602 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,04503171 0,0517413 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,04503171 0,0517166 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,04503171 0,05169193 ! neuron migration GO:0001764 79 42 0,000 0,04503171 0,05166728 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,04503171 0,05164265 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,04607955 0,05281915 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,04607955 0,052794 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,04607955 0,05276887 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,04607955 0,05274377 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,04607955 0,05271869 ! neural tube development GO:0021915 77 43 0,000 0,04607955 0,05269363 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,04607955 0,0526686 ! striated muscle contraction GO:0006941 77 43 0,000 0,04607955 0,05264359 ! phagocytosis GO:0006909 90 43 0,000 0,04607955 0,05261861 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,04607955 0,05259364 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,04712628 0,05376284 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,04712628 0,05373736 ! male sex differentiation GO:0046661 76 44 0,000 0,04712628 0,05371191 ! double-strand break repair GO:0006302 81 44 0,000 0,04712628 0,05368648 ! biopolymer methylation GO:0043414 84 44 0,000 0,04712628 0,05366107 ! B cell differentiation GO:0030183 107 44 0,000 0,04712628 0,05363568 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,04712628 0,05361032 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,04712628 0,05358499 ! maintenance of location in cell GO:0051651 97 44 0,000 0,04712628 0,05355968 ! glycolysis GO:0006096 65 45 0,000 0,0481719 0,05472219 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,0481719 0,05469636 ! leukocyte migration GO:0050900 68 45 0,000 0,0481719 0,05467056 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,0481719 0,05464479 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,0481719 0,05461903 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,0481719 0,05459331 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,0481719 0,0545676 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,0481719 0,05454192 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,0481719 0,05451627 ! cell growth GO:0016049 84 45 0,000 0,0481719 0,05449064 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0492164 0,05564599 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,0492164 0,05561985 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0492164 0,05559374 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0492164 0,05556765 ! pigmentation GO:0043473 100 46 0,000 0,0492164 0,05554159 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0502598 0,05669248 ! response to calcium ion GO:0051592 81 47 0,000 0,0502598 0,05666592 ! endosome transport GO:0016197 108 47 0,000 0,0502598 0,05663938 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,0502598 0,05661286 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,0502598 0,05658637 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0502598 0,0565599 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0502598 0,05653346 ! JNK cascade GO:0007254 91 47 0,000 0,0502598 0,05650704 ! methylation GO:0032259 90 47 0,000 0,0502598 0,05648065 ! Notch signaling pathway GO:0007219 96 48 0,000 0,05130208 0,05762502 ! cellular component disassembly GO:0022411 86 48 0,000 0,05130208 0,05759813 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,05130208 0,05757127 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,05130208 0,05754443 ! activation of caspase activity GO:0006919 84 48 0,000 0,05130208 0,05751761 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,05130208 0,05749082 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,05130208 0,05746406 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,05130208 0,05743732 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,05130208 0,0574106 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,05234325 0,05854852 ! regulation of action potential GO:0001508 95 49 0,000 0,05234325 0,05852131 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,05234325 0,05849413 ! regulation of ion transport GO:0043269 77 49 0,000 0,05234325 0,05846697 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,05234325 0,05843984 ! peptide metabolic process GO:0006518 76 49 0,000 0,05234325 0,05841274 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,05234325 0,05838566 ! endocrine system development GO:0035270 104 49 0,000 0,05234325 0,0583586 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,05234325 0,05833157 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,05234325 0,05830457 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,05234325 0,05827759 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,05234325 0,05825063 ! neuromuscular process GO:0050905 99 50 0,000 0,05338332 0,05938061 ! regulation of ossification GO:0030278 117 50 0,000 0,05338332 0,05935317 ! inner ear development GO:0048839 79 50 0,000 0,05338332 0,05932575 ! histone modification GO:0016570 91 50 0,000 0,05338332 0,05929837 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,05338332 0,059271 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,05338332 0,05924366 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,05338332 0,05921635 ! positive regulation of binding GO:0051099 78 51 0,000 0,05442227 0,06034101 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,05442227 0,06031322 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,05442227 0,06028545 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,05442227 0,0602577 ! excretion GO:0007588 83 51 0,000 0,05442227 0,06022999 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,05442227 0,0602023 ! chromatin remodeling GO:0006338 109 51 0,000 0,05442227 0,06017463 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,05442227 0,06014699 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,05442227 0,06011937 ! vesicle organization GO:0016050 107 51 0,000 0,05442227 0,06009178 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,05442227 0,06006422 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,05442227 0,06003668 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,05546013 0,06115356 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,05546013 0,06112554 ! membrane fusion GO:0006944 110 52 0,000 0,05546013 0,06109756 ! covalent chromatin modification GO:0016569 101 52 0,000 0,05546013 0,06106959 ! amino acid activation GO:0043038 92 52 0,000 0,05546013 0,06104166 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,05546013 0,06101375 ! synapse organization GO:0050808 85 52 0,000 0,05546013 0,06098586 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,05649687 0,06209752 ! RNA catabolic process GO:0006401 93 53 0,000 0,05649687 0,06206917 ! regulation of translational initiation GO:0006446 82 53 0,000 0,05649687 0,06204084 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,05649687 0,06201254 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,05649687 0,06198426 ! cell maturation GO:0048469 100 53 0,000 0,05649687 0,06195601 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,05753252 0,06306298 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,05753252 0,06303426 ! cell recognition GO:0008037 85 54 0,000 0,05753252 0,06300557 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,05753252 0,06297691 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,05753252 0,06294827 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,05753252 0,06291965 ! chloride transport GO:0006821 90 55 0,000 0,05856706 0,06402197 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,05856706 0,06399289 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,05856706 0,06396384 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,05856706 0,06393482 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,05856706 0,06390583 ! aging GO:0007568 103 55 0,000 0,05856706 0,06387686 ! gastrulation GO:0007369 112 55 0,000 0,05856706 0,06384791 ! heart morphogenesis GO:0003007 97 55 0,000 0,05856706 0,063819 ! RNA elongation GO:0006354 79 55 0,000 0,05856706 0,06379011 ! nuclear export GO:0051168 97 55 0,000 0,05856706 0,06376124 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,05856706 0,0637324 ! sensory perception of smell GO:0007608 80 56 0,000 0,0596005 0,06482767 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,0596005 0,06479838 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,0596005 0,06476911 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,0596005 0,06473987 ! regulation of DNA replication GO:0006275 101 56 0,000 0,0596005 0,06471065 ! proton transport GO:0015992 94 56 0,000 0,0596005 0,06468146 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,06063284 0,06577214 ! muscle fiber development GO:0048747 112 57 0,000 0,06063284 0,0657425 ! positive regulation of cell migration GO:0030335 126 57 0,000 0,06063284 0,06571289 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,06063284 0,0656833 ! maintenance of location GO:0051235 118 57 0,000 0,06063284 0,06565374 ! hydrogen transport GO:0006818 97 58 0,000 0,06166408 0,06674034 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,06166408 0,06671033 ! regulation of endocytosis GO:0030100 91 58 0,000 0,06166408 0,06668035 ! adult behavior GO:0030534 99 58 0,000 0,06166408 0,0666504 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,06166408 0,06662047 ! positive regulation of secretion GO:0051047 95 59 0,000 0,06269423 0,06770301 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,06269423 0,06767264 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,06269423 0,06764229 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,06269423 0,06761197 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,06269423 0,06758168 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,06372327 0,06866019 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,06372327 0,06862945 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,06372327 0,06859874 ! regulation of heart contraction GO:0008016 110 60 0,000 0,06372327 0,06856807 ! camera-type eye development GO:0043010 116 60 0,000 0,06372327 0,06853741 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,06372327 0,06850679 ! kidney development GO:0001822 122 60 0,000 0,06372327 0,06847619 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,06475122 0,06954975 ! mesoderm development GO:0007498 119 61 0,000 0,06475122 0,06951872 ! tRNA processing GO:0008033 89 61 0,000 0,06475122 0,06948771 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,06475122 0,06945673 ! ear development GO:0043583 103 62 0,000 0,06577808 0,07052677 ! gonad development GO:0008406 98 62 0,000 0,06577808 0,07049535 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,06577808 0,07046396 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,06680384 0,07153095 ! detection of external stimulus GO:0009581 91 63 0,000 0,06680384 0,07149913 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,06680384 0,07146734 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,06680384 0,07143558 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,06782852 0,07249907 ! cell redox homeostasis GO:0045454 102 64 0,000 0,06782852 0,07246688 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,06782852 0,07243471 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,06782852 0,07240258 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,06782852 0,07237047 ! positive regulation of cell motion GO:0051272 146 64 0,000 0,06782852 0,07233839 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0688521 0,07339749 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0688521 0,07336499 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0688521 0,07333251 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,06987459 0,07438861 ! actin filament organization GO:0007015 148 66 0,000 0,06987459 0,07435571 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,06987459 0,07432284 ! extracellular matrix organization GO:0030198 133 66 0,000 0,06987459 0,07428999 ! secondary metabolic process GO:0019748 116 66 0,000 0,06987459 0,07425718 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,07089599 0,07530938 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,07089599 0,07527615 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,07089599 0,07524294 ! lung development GO:0030324 144 67 0,000 0,07089599 0,07520976 ! chromosome segregation GO:0007059 113 67 0,000 0,07089599 0,07517662 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,07089599 0,0751435 ! hexose catabolic process GO:0019320 104 67 0,000 0,07089599 0,07511041 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,07089599 0,07507735 ! adaptive immune response GO:0002250 119 67 0,000 0,07089599 0,07504432 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,07089599 0,07501132 ! amino acid transport GO:0006865 125 68 0,000 0,0719163 0,07605742 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,0719163 0,076024 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,0719163 0,07599061 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,0719163 0,07595725 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,0719163 0,07592392 ! regulation of lipase activity GO:0060191 130 68 0,000 0,0719163 0,07589062 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,0719163 0,07585735 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,0719163 0,07582411 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,07293553 0,07686504 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,07293553 0,07683138 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,07293553 0,07679776 ! urogenital system development GO:0001655 137 69 0,000 0,07293553 0,07676417 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,07293553 0,0767306 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,07293553 0,07669706 ! antigen processing and presentation GO:0019882 104 69 0,000 0,07293553 0,07666356 ! appendage morphogenesis GO:0035107 135 70 0,000 0,07395367 0,0776998 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,07395367 0,07766588 ! amine catabolic process GO:0009310 117 71 0,000 0,07497073 0,07869964 ! reproductive structure development GO:0048608 113 71 0,000 0,07497073 0,07866532 ! appendage development GO:0048736 136 71 0,000 0,07497073 0,07863103 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,07497073 0,07859676 ! B cell activation GO:0042113 160 71 0,000 0,07497073 0,07856253 ! regulation of immune effector process GO:0002697 137 71 0,000 0,07497073 0,07852833 ! acute inflammatory response GO:0002526 113 72 0,000 0,0759867 0,07955788 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,0759867 0,07952327 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,0759867 0,0794887 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,0759867 0,07945415 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,0759867 0,07941964 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,0759867 0,07938515 ! respiratory system development GO:0060541 153 72 0,000 0,0759867 0,0793507 ! learning or memory GO:0007611 147 73 0,000 0,0770016 0,08037563 ! regulation of blood pressure GO:0008217 125 73 0,000 0,0770016 0,08034078 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,0770016 0,08030595 ! axon guidance GO:0007411 139 73 0,000 0,0770016 0,08027116 ! fertilization GO:0009566 90 73 0,000 0,0770016 0,0802364 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,07801541 0,08125761 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,07801541 0,08122244 ! neurotransmitter transport GO:0006836 123 74 0,000 0,07801541 0,08118731 ! meiosis GO:0007126 121 74 0,000 0,07801541 0,08115221 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,07801541 0,08111714 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,07801541 0,0810821 ! eye development GO:0001654 143 74 0,000 0,07801541 0,08104709 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,07902814 0,08206375 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,07902814 0,08202834 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,07902814 0,08199297 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,07902814 0,08195763 ! meiotic cell cycle GO:0051321 122 75 0,000 0,07902814 0,08192232 ! rhythmic process GO:0048511 128 75 0,000 0,07902814 0,08188704 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,07902814 0,08185179 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,08003979 0,08286391 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,08003979 0,08282827 ! defense response to bacterium GO:0042742 89 76 0,000 0,08003979 0,08279266 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,08003979 0,08275708 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,08003979 0,08272154 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,08105037 0,08373 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,08105037 0,08369407 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,08105037 0,08365816 ! blood coagulation GO:0007596 146 78 0,000 0,08205986 0,08466382 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,08205986 0,08462753 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,08205986 0,08459127 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,08306829 0,08559413 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,08306829 0,08555749 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,08306829 0,08552088 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,08306829 0,0854843 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,08407564 0,08648396 ! response to metal ion GO:0010038 140 80 0,000 0,08407564 0,086447 ! inorganic anion transport GO:0015698 138 80 0,000 0,08407564 0,08641007 ! T cell activation GO:0042110 168 81 0,000 0,08508191 0,08740695 ! digestion GO:0007586 112 81 0,000 0,08508191 0,08736965 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,08508191 0,08733237 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,08508191 0,08729513 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,08508191 0,08725792 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,08608712 0,08825121 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,08608712 0,08821363 ! response to drug GO:0042493 143 82 0,000 0,08608712 0,08817608 ! response to nutrient GO:0007584 125 82 0,000 0,08608712 0,08813855 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,08608712 0,08810106 ! regulation of lyase activity GO:0051339 160 83 0,000 0,08709125 0,08909079 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,08809431 0,09007859 ! hemostasis GO:0007599 158 84 0,000 0,08809431 0,09004032 ! negative regulation of growth GO:0045926 155 84 0,000 0,08809431 0,09000209 ! regulation of ligase activity GO:0051340 142 84 0,000 0,08809431 0,08996389 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,08809431 0,08992572 ! nucleosome assembly GO:0006334 122 85 0,000 0,08909631 0,09090997 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,08909631 0,09087143 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,08909631 0,09083293 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,09009723 0,09181446 ! response to inorganic substance GO:0010035 153 86 0,000 0,09009723 0,09177559 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,09009723 0,09173675 ! chromatin assembly GO:0031497 124 86 0,000 0,09009723 0,09169794 ! alcohol catabolic process GO:0046164 130 86 0,000 0,09009723 0,09165917 ! amine transport GO:0015837 155 86 0,000 0,09009723 0,09162043 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,09109709 0,09259806 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,09109709 0,09255895 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,09209589 0,09353428 ! regulation of DNA binding GO:0051101 155 88 0,000 0,09209589 0,09349481 ! gland development GO:0048732 206 88 0,000 0,09209589 0,09345538 ! regulation of neurological system process GO:0031644 148 88 0,000 0,09209589 0,09341598 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,09209589 0,09337661 ! cellular defense response GO:0006968 114 89 0,000 0,09309362 0,09434846 ! ossification GO:0001503 188 90 0,000 0,09409028 0,09531841 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,09409028 0,09527829 ! sex differentiation GO:0007548 145 90 0,000 0,09409028 0,09523821 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,09409028 0,09519816 ! bone development GO:0060348 189 91 0,000 0,09508589 0,09616505 ! sterol metabolic process GO:0016125 152 91 0,000 0,09508589 0,09612464 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,09508589 0,09608427 ! regulation of defense response GO:0031347 149 92 0,000 0,09608043 0,0970485 ! nucleosome organization GO:0034728 138 92 0,000 0,09608043 0,09700777 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,09608043 0,09696708 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,09707391 0,09792865 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,09707391 0,09788761 ! regulation of membrane potential GO:0042391 164 93 0,000 0,09707391 0,0978466 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,09707391 0,09780563 ! female pregnancy GO:0007565 164 94 0,000 0,09806634 0,09876417 ! transcription initiation GO:0006352 153 94 0,000 0,09806634 0,09872285 ! regulation of T cell activation GO:0050863 158 94 0,000 0,09806634 0,09868156 ! forebrain development GO:0030900 188 95 0,000 0,09905771 0,09963748 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,09905771 0,09959584 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,10004802 0,10054951 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,10004802 0,10050753 ! positive regulation of immune response GO:0050778 156 96 0,000 0,10004802 0,10046558 ! detection of stimulus GO:0051606 151 96 0,000 0,10004802 0,10042367 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,10103727 0,10137434 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,10103727 0,10133209 ! hormone metabolic process GO:0042445 157 97 0,000 0,10103727 0,10128986 ! response to virus GO:0009615 160 98 0,000 0,10202547 0,10223794 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,10202547 0,10219537 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,10301262 0,10314122 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,10301262 0,10309832 ! skeletal muscle tissue development GO:0007519 186 99 0,000 0,10301262 0,10305545 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 0,000 0,10399871 0,10399871