pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/657-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 6,000 1,823E-09 4,454E-06 ! regulation of epithelial cell proliferation GO:0050678 122 45 4,000 4,468E-08 5,458E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 5,004E-08 4,075E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 1,123E-07 6,861E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,501E-07 7,334E-05 ! regulation of granule cell precursor proliferation GO:0021936 12 7 2,000 3,268E-07 1,33E-04 GO:0021940|positive regulation of granule cell precursor proliferation, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 5,22E-07 1,822E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 7,818E-07 2,387E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 1,531E-06 4,156E-04 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 2,646E-06 6,463E-04 ! positive regulation of cell cycle GO:0045787 96 48 3,000 3,496E-06 7,764E-04 ! response to UV GO:0009411 120 55 3,000 6,059E-06 1,233E-03 ! activation of MAPKK activity GO:0000186 43 17 2,000 6,252E-06 1,175E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 7,49E-06 1,307E-03 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 2,000 8,881E-06 1,446E-03 ! G1 phase GO:0051318 44 22 2,000 1,405E-05 2,145E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 1,501E-05 2,158E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,501E-05 2,038E-03 ! homeostasis of number of cells GO:0048872 131 69 3,000 1,501E-05 1,93E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,59E-05 1,942E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,841E-05 2,141E-03 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 1,841E-05 2,044E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,841E-05 1,955E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,982E-05 2,018E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 2,089E-05 2,041E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 2,089E-05 1,962E-03 ! molting cycle process GO:0022404 52 26 2,000 2,357E-05 2,133E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 2,357E-05 2,057E-03 GO:0045936|negative regulation of phosphate metabolic process, ! insulin receptor signaling pathway GO:0008286 66 27 2,000 2,648E-05 2,231E-03 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 2,834E-05 2,308E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,961E-05 2,334E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 2,961E-05 2,261E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 3,12E-05 2,31E-03 GO:0045937|positive regulation of phosphate metabolic process, ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 3,298E-05 2,37E-03 ! erythrocyte differentiation GO:0030218 62 31 2,000 4,044E-05 2,823E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 4,044E-05 2,745E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 1,000 4,493E-05 2,967E-03 ! anagen GO:0042640 7 5 1,000 4,493E-05 2,889E-03 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 1,000 4,493E-05 2,815E-03 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! response to food GO:0032094 6 5 1,000 4,493E-05 2,744E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,493E-05 2,677E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 4,493E-05 2,613E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 4,493E-05 2,553E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 4,493E-05 2,495E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,493E-05 2,439E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,493E-05 2,386E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 4,878E-05 2,535E-03 ! regulation of ARF GTPase activity GO:0032312 73 34 2,000 5,359E-05 2,728E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 6,73E-05 3,356E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 6,73E-05 3,288E-03 ! hair follicle maturation GO:0048820 8 6 1,000 6,73E-05 3,224E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 6,73E-05 3,162E-03 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 1,000 6,73E-05 3,102E-03 ! cellular anion homeostasis GO:0030002 11 6 1,000 6,73E-05 3,045E-03 GO:0055081|anion homeostasis, ! cellular response to insulin stimulus GO:0032869 85 38 2,000 7,509E-05 3,335E-03 ! erythrocyte homeostasis GO:0034101 75 39 2,000 8,122E-05 3,543E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 9,409E-05 4,033E-03 ! vesicle fusion GO:0006906 20 7 1,000 9,409E-05 3,963E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 9,409E-05 3,896E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 9,409E-05 3,831E-03 ! gliogenesis GO:0042063 91 41 2,000 9,445E-05 3,783E-03 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 1,09E-04 4,295E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 1,253E-04 4,858E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,253E-04 4,782E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,253E-04 4,709E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,253E-04 4,637E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 1,000 1,253E-04 4,568E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 1,253E-04 4,501E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,253E-04 4,436E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,253E-04 4,372E-03 ! response to insulin stimulus GO:0032868 98 47 2,000 1,423E-04 4,898E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,609E-04 5,458E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 1,609E-04 5,383E-03 GO:0010469|regulation of receptor activity, ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,609E-04 5,31E-03 ! erythrocyte development GO:0048821 17 9 1,000 1,609E-04 5,24E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,609E-04 5,171E-03 ! regulation of ARF protein signal transduction GO:0032012 115 50 2,000 1,713E-04 5,434E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 2,008E-04 6,289E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 2,008E-04 6,209E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 2,008E-04 6,132E-03 ! glucan biosynthetic process GO:0009250 14 10 1,000 2,008E-04 6,056E-03 GO:0005978|glycogen biosynthetic process, ! induction of an organ GO:0001759 17 10 1,000 2,008E-04 5,982E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,008E-04 5,91E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 2,663E-04 7,746E-03 ! positive regulation of organelle organization GO:0010638 108 58 2,000 2,663E-04 7,655E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 2,937E-04 8,342E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,937E-04 8,247E-03 ! negative regulation of endothelial cell migration GO:0010596 26 12 1,000 2,937E-04 8,153E-03 ! T cell homeostasis GO:0043029 28 12 1,000 2,937E-04 8,061E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 2,937E-04 7,972E-03 ! developmental induction GO:0031128 22 12 1,000 2,937E-04 7,884E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 2,937E-04 7,798E-03 ! organelle fusion GO:0048284 36 13 1,000 3,466E-04 9,105E-03 ! gland morphogenesis GO:0022612 31 13 1,000 3,466E-04 9,008E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 3,466E-04 8,913E-03 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 3,466E-04 8,82E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 3,563E-04 8,975E-03 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 3,563E-04 8,883E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 3,73E-04 9,205E-03 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 3,902E-04 9,532E-03 ! hair follicle morphogenesis GO:0031069 27 14 1,000 4,038E-04 9,767E-03 ! lipid localization GO:0010876 32 14 1,000 4,038E-04 9,671E-03 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 4,038E-04 9,577E-03 ! negative regulation of cell growth GO:0030308 142 67 2,000 4,078E-04 9,58E-03 ! activation of MAPK activity GO:0000187 124 67 2,000 4,078E-04 9,489E-03 ! myeloid cell differentiation GO:0030099 126 67 2,000 4,078E-04 9,399E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 4,447E-04 0,01015297 ! G1/S transition checkpoint GO:0031575 37 15 1,000 4,653E-04 0,01052467 ! regulation of vasodilation GO:0042312 27 15 1,000 4,653E-04 0,01042812 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 4,653E-04 0,01033332 ! lymphocyte homeostasis GO:0002260 33 15 1,000 4,653E-04 0,01024022 ! actin filament polymerization GO:0030041 27 15 1,000 4,653E-04 0,01014879 ! cell cycle checkpoint GO:0000075 145 71 2,000 4,836E-04 0,01045537 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 5,31E-04 0,01137935 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 5,31E-04 0,0112804 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! DNA replication initiation GO:0006270 28 16 1,000 5,31E-04 0,01118316 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 6,01E-04 0,01254851 ! regulation of survival gene product expression GO:0045884 38 17 1,000 6,01E-04 0,01244217 ! DNA unwinding during replication GO:0006268 26 17 1,000 6,01E-04 0,01233761 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 6,752E-04 0,01374509 ! positive regulation of proteolysis GO:0045862 36 18 1,000 6,752E-04 0,01363149 ! epidermis morphogenesis GO:0048730 43 18 1,000 6,752E-04 0,01351976 ! activation of protein kinase activity GO:0032147 170 80 2,000 6,857E-04 0,01361848 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 7,535E-04 0,01484602 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 7,535E-04 0,01472725 ! negative regulation of growth GO:0045926 168 85 2,000 8,18E-04 0,01585995 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 8,18E-04 0,01573507 ! positive regulation of angiogenesis GO:0045766 50 20 1,000 8,361E-04 0,01595797 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 8,361E-04 0,01583426 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 8,361E-04 0,01571246 ! DNA duplex unwinding GO:0032508 30 20 1,000 8,361E-04 0,01559252 GO:0032392|DNA geometric change, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 8,361E-04 0,01547439 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 8,361E-04 0,01535804 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 8,361E-04 0,01524343 ! nucleosome assembly GO:0006334 126 87 2,000 8,751E-04 0,01583686 ! chromatin assembly GO:0031497 128 88 2,000 9,046E-04 0,01625035 ! lipid phosphorylation GO:0046834 43 21 1,000 9,228E-04 0,01645626 ! regulation of vasoconstriction GO:0019229 40 21 1,000 9,228E-04 0,01633701 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 1,014E-03 0,01781673 ! inactivation of MAPK activity GO:0000188 45 22 1,000 1,014E-03 0,01768947 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 1,014E-03 0,01756401 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 1,014E-03 0,01744032 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,014E-03 0,01731836 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,014E-03 0,01719809 ! protein-DNA complex assembly GO:0065004 134 92 2,000 1,029E-03 0,01733588 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 1,109E-03 0,01855227 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 1,109E-03 0,01842607 ! nucleosome organization GO:0034728 143 95 2,000 1,129E-03 0,01863465 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,208E-03 0,01980391 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,208E-03 0,01967189 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,208E-03 0,01954161 ! membrane depolarization GO:0051899 45 24 1,000 1,208E-03 0,01941305 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,208E-03 0,01928616 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 1,311E-03 0,02079828 ! regulation of transmembrane transport GO:0034762 39 25 1,000 1,311E-03 0,0206641 ! vasculogenesis GO:0001570 49 25 1,000 1,311E-03 0,02053164 ! leukocyte homeostasis GO:0001776 50 25 1,000 1,311E-03 0,02040087 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,418E-03 0,02193068 ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,418E-03 0,02179275 ! regulation of blood coagulation GO:0030193 46 26 1,000 1,418E-03 0,02165655 ! positive regulation of nuclear division GO:0051785 41 26 1,000 1,418E-03 0,02152204 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,418E-03 0,02138918 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 1,53E-03 0,02292685 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 1,53E-03 0,02278705 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,53E-03 0,02264895 ! vesicle docking GO:0048278 55 28 1,000 1,645E-03 0,02421072 ! glutathione metabolic process GO:0006749 42 28 1,000 1,645E-03 0,02406574 ! respiratory gaseous exchange GO:0007585 61 29 1,000 1,765E-03 0,02565901 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 1,888E-03 0,02729135 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 1,888E-03 0,02713081 ! regulation of B cell activation GO:0050864 55 30 1,000 1,888E-03 0,02697215 ! regulation of coagulation GO:0050818 52 30 1,000 1,888E-03 0,02681533 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 2,015E-03 0,02845959 ! response to heat GO:0009408 54 31 1,000 2,015E-03 0,02829603 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 2,147E-03 0,02996849 ! positive regulation of catabolic process GO:0009896 72 32 1,000 2,147E-03 0,02979821 ! cholesterol homeostasis GO:0042632 60 33 1,000 2,282E-03 0,03149789 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 2,282E-03 0,03132093 ! glial cell differentiation GO:0010001 67 34 1,000 2,421E-03 0,03304686 ! cholesterol transport GO:0030301 62 34 1,000 2,421E-03 0,03286327 ! cell fate specification GO:0001708 56 34 1,000 2,421E-03 0,0326817 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,421E-03 0,03250213 ! negative regulation of secretion GO:0051048 68 35 1,000 2,565E-03 0,03423624 ! membrane docking GO:0022406 69 35 1,000 2,565E-03 0,03405017 ! sterol transport GO:0015918 63 35 1,000 2,565E-03 0,03386612 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,565E-03 0,03368404 ! placenta development GO:0001890 53 35 1,000 2,565E-03 0,03350391 ! regulation of proteolysis GO:0030162 77 36 1,000 2,712E-03 0,0352373 ! tissue remodeling GO:0048771 78 37 1,000 2,863E-03 0,03700261 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 2,863E-03 0,03680786 ! regulation of microtubule-based process GO:0032886 86 37 1,000 2,863E-03 0,03661515 ! neutral lipid metabolic process GO:0006638 54 38 1,000 3,018E-03 0,03839494 GO:0006639|acylglycerol metabolic process, ! glycogen metabolic process GO:0005977 63 38 1,000 3,018E-03 0,038196 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 3,176E-03 0,03999784 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 3,176E-03 0,03979272 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 3,176E-03 0,0395897 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 3,339E-03 0,0414046 ! lipid homeostasis GO:0055088 75 40 1,000 3,339E-03 0,04119549 ! glycerol ether metabolic process GO:0006662 57 40 1,000 3,339E-03 0,04098847 ! organic ether metabolic process GO:0018904 59 42 1,000 3,675E-03 0,0448946 ! regulation of protein secretion GO:0050708 77 42 1,000 3,675E-03 0,04467124 ! glucose transport GO:0015758 66 43 1,000 3,849E-03 0,04655408 ! striated muscle cell differentiation GO:0051146 91 43 1,000 3,849E-03 0,04632475 ! energy reserve metabolic process GO:0006112 76 44 1,000 4,027E-03 0,04822619 ! hexose transport GO:0008645 68 44 1,000 4,027E-03 0,04799094 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 4,027E-03 0,04775797 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 4,209E-03 0,04966924 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 4,209E-03 0,04943044 ! developmental growth GO:0048589 88 45 1,000 4,209E-03 0,04919393 ! glycolysis GO:0006096 71 46 1,000 4,394E-03 0,05111454 ! negative regulation of cell migration GO:0030336 122 46 1,000 4,394E-03 0,05087229 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 4,394E-03 0,05063233 ! cell growth GO:0016049 90 46 1,000 4,394E-03 0,05039462 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 4,775E-03 0,05451557 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 4,972E-03 0,05649307 ! protein homooligomerization GO:0051260 84 49 1,000 4,972E-03 0,05623152 ! regulation of ossification GO:0030278 123 50 1,000 5,172E-03 0,05822423 ! peptide metabolic process GO:0006518 80 51 1,000 5,375E-03 0,06023964 ! response to temperature stimulus GO:0009266 84 51 1,000 5,375E-03 0,05996457 ! negative regulation of immune system process GO:0002683 101 51 1,000 5,375E-03 0,059692 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 5,583E-03 0,06171365 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 5,583E-03 0,06143566 ! positive regulation of growth GO:0045927 96 53 1,000 5,794E-03 0,06347106 ! vesicle organization GO:0016050 127 53 1,000 5,794E-03 0,06318771 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 5,794E-03 0,06290687 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 125 54 1,000 6,008E-03 0,06494775 ! activation of phospholipase C activity GO:0007202 110 54 1,000 6,008E-03 0,06466164 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 6,008E-03 0,06437803 ! membrane fusion GO:0006944 122 54 1,000 6,008E-03 0,06409691 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 6,226E-03 0,06613527 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 6,226E-03 0,06584897 ! regulation of protein polymerization GO:0032271 117 55 1,000 6,226E-03 0,06556514 ! negative regulation of cell motion GO:0051271 142 55 1,000 6,226E-03 0,06528375 ! glucose catabolic process GO:0006007 88 56 1,000 6,448E-03 0,06731953 ! regulation of protein catabolic process GO:0042176 126 56 1,000 6,448E-03 0,06703307 ! regulation of bone remodeling GO:0046850 143 57 1,000 6,673E-03 0,06908105 ! regulation of phospholipase activity GO:0010517 113 57 1,000 6,673E-03 0,06878957 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 6,902E-03 0,07084934 ! regulation of tissue remodeling GO:0034103 146 58 1,000 6,902E-03 0,0705529 ! positive regulation of lipase activity GO:0060193 115 58 1,000 6,902E-03 0,07025893 ! lipid modification GO:0030258 112 60 1,000 7,37E-03 0,0747137 ! regulation of homeostatic process GO:0032844 148 62 1,000 7,853E-03 0,07927288 ! regulation of protein complex assembly GO:0043254 132 63 1,000 8,099E-03 0,08142294 ! regulation of mitosis GO:0007088 112 63 1,000 8,099E-03 0,08108924 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 8,859E-03 0,08833233 ! hexose catabolic process GO:0019320 113 68 1,000 9,382E-03 0,09317141 ! regulation of lipase activity GO:0060191 137 68 1,000 9,382E-03 0,0927942 ! lung development GO:0030324 165 69 1,000 9,649E-03 0,09504808 ! developmental maturation GO:0021700 128 69 1,000 9,649E-03 0,09466636 ! cell redox homeostasis GO:0045454 114 70 1,000 9,919E-03 0,09692753 ! germ cell development GO:0007281 133 70 1,000 9,919E-03 0,09654137 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,01019239 0,09880957 ! carbohydrate transport GO:0008643 114 72 1,000 0,01046921 0,10109198 ! respiratory tube development GO:0030323 171 72 1,000 0,01046921 0,10069398 ! actin filament organization GO:0007015 167 72 1,000 0,01046921 0,1002991 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,01046921 0,09990731 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01064595 0,10119866 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01064595 0,10080642 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01064595 0,1004172 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01064595 0,10003098 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01064595 0,09964772 ! neuron fate determination GO:0048664 7 5 0,000 0,01064595 0,09926739 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01064595 0,09888995 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01064595 0,09851536 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01064595 0,09814361 ! polyol transport GO:0015791 12 5 0,000 0,01064595 0,09777465 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01064595 0,09740845 ! response to superoxide GO:0000303 10 5 0,000 0,01064595 0,09704498 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01064595 0,09668422 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01064595 0,09632613 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01064595 0,09597069 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01064595 0,09561785 ! female meiosis GO:0007143 10 5 0,000 0,01064595 0,0952676 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01064595 0,09491991 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01064595 0,09457475 ! hypothalamus development GO:0021854 9 5 0,000 0,01064595 0,09423209 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01064595 0,0938919 ! cobalt ion transport GO:0006824 11 5 0,000 0,01064595 0,09355416 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01064595 0,09321884 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01064595 0,09288591 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01064595 0,09255536 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01064595 0,09222715 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01064595 0,09190126 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01064595 0,09157766 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01064595 0,09125634 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01064595 0,09093726 ! transposition GO:0032196 9 5 0,000 0,01064595 0,0906204 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01064595 0,09030575 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01064595 0,08999327 ! negative chemotaxis GO:0050919 16 5 0,000 0,01064595 0,08968295 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01064595 0,08937476 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01064595 0,08906868 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01064595 0,0887647 ! behavioral response to pain GO:0048266 10 5 0,000 0,01064595 0,08846277 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01064595 0,0881629 ! Notch receptor processing GO:0007220 11 5 0,000 0,01064595 0,08786505 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01064595 0,08756921 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01064595 0,08727535 ! micturition GO:0060073 9 5 0,000 0,01064595 0,08698346 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01064595 0,08669352 ! copulation GO:0007620 9 5 0,000 0,01064595 0,0864055 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01064595 0,08611939 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01064595 0,08583517 ! bioluminescence GO:0008218 9 5 0,000 0,01064595 0,08555281 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01064595 0,08527231 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01064595 0,08499365 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01064595 0,08471679 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01064595 0,08444174 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01064595 0,08416846 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01064595 0,08389695 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01064595 0,08362719 ! grooming behavior GO:0007625 6 5 0,000 0,01064595 0,08335915 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01064595 0,08309283 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01064595 0,0828282 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01064595 0,08256526 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01064595 0,08230397 ! response to protozoan GO:0001562 13 5 0,000 0,01064595 0,08204434 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01064595 0,08178634 ! lymph vessel development GO:0001945 10 5 0,000 0,01064595 0,08152996 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01064595 0,08127517 ! endochondral ossification GO:0001958 17 5 0,000 0,01064595 0,08102198 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01064595 0,08077036 ! single strand break repair GO:0000012 8 5 0,000 0,01064595 0,0805203 ! parathyroid gland development GO:0060017 14 5 0,000 0,01064595 0,08027178 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01064595 0,08002479 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01064595 0,07977931 ! cytokine secretion GO:0050663 15 5 0,000 0,01064595 0,07953534 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01064595 0,07929285 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01064595 0,07905184 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01064595 0,07881229 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01064595 0,07857419 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01064595 0,07833752 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01064595 0,07810227 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01064595 0,07786843 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01064595 0,07763599 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01064595 0,07740493 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01064595 0,07717524 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01064595 0,07694691 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01064595 0,07671993 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01064595 0,07649428 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01064595 0,07626996 ! microvillus organization GO:0032528 8 5 0,000 0,01064595 0,07604695 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01064595 0,07582524 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01064595 0,07560481 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01064595 0,07538567 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01064595 0,07516779 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01064595 0,07495117 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01064595 0,07473579 ! polyol catabolic process GO:0046174 9 5 0,000 0,01064595 0,07452165 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01064595 0,07430873 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01064595 0,07409702 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01064595 0,07388652 ! muscle cell migration GO:0014812 8 5 0,000 0,01064595 0,07367721 ! mitochondrial fission GO:0000266 8 5 0,000 0,01064595 0,07346908 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01064595 0,07326213 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01064595 0,07305634 ! mRNA transcription GO:0009299 10 5 0,000 0,01064595 0,0728517 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01064595 0,0726482 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01064595 0,07244584 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01064595 0,0722446 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01064595 0,07204448 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01064595 0,07184546 ! monocyte activation GO:0042117 10 5 0,000 0,01064595 0,07164754 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01064595 0,0714507 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01064595 0,07125495 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01064595 0,07106026 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01064595 0,07086664 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01064595 0,07067406 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01064595 0,07048254 ! forebrain neuron development GO:0021884 13 5 0,000 0,01064595 0,07029204 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01064595 0,07010258 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01064595 0,06991413 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01064595 0,06972669 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01064595 0,06954026 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01064595 0,06935482 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01064595 0,06917036 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01064595 0,06898689 ! lipid glycosylation GO:0030259 7 5 0,000 0,01064595 0,06880438 ! nucleobase transport GO:0015851 6 5 0,000 0,01064595 0,06862284 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01064595 0,06844225 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01064595 0,06826261 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01064595 0,06808392 ! basic amino acid transport GO:0015802 12 5 0,000 0,01064595 0,06790615 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01064595 0,06772931 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01064595 0,06755339 ! actin nucleation GO:0045010 11 5 0,000 0,01064595 0,06737838 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01064595 0,06720428 ! depurination GO:0045007 5 5 0,000 0,01064595 0,06703107 ! depyrimidination GO:0045008 10 5 0,000 0,01064595 0,06685875 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01064595 0,06668732 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01064595 0,06651677 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01064595 0,06634708 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01064595 0,06617826 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01064595 0,06601029 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01064595 0,06584318 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01064595 0,06567691 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01064595 0,06551148 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01064595 0,06534687 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01064595 0,0651831 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01064595 0,06502014 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01064595 0,06485799 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01064595 0,06469666 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01064595 0,06453612 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01064595 0,06437638 ! response to arsenic GO:0046685 11 5 0,000 0,01064595 0,06421742 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01064595 0,06405925 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01064595 0,06390186 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01064595 0,06374523 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01064595 0,06358938 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01064595 0,06343428 ! response to mercury ion GO:0046689 8 5 0,000 0,01064595 0,06327994 ! response to cadmium ion GO:0046686 7 5 0,000 0,01064595 0,06312635 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01064595 0,0629735 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01064595 0,06282139 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01064595 0,06267001 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01064595 0,06251936 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01064595 0,06236944 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01064595 0,06222023 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01064595 0,06207173 ! decidualization GO:0046697 11 5 0,000 0,01064595 0,06192394 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01064595 0,06177685 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01064595 0,06163046 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01064595 0,06148477 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01064595 0,06133975 ! embryonic cleavage GO:0040016 6 5 0,000 0,01064595 0,06119543 ! peroxisome fission GO:0016559 5 5 0,000 0,01064595 0,06105177 ! histone demethylation GO:0016577 13 5 0,000 0,01064595 0,0609088 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01064595 0,06076649 ! mitotic recombination GO:0006312 9 5 0,000 0,01064595 0,06062484 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01064595 0,06048385 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01064595 0,06034352 ! metaphase plate congression GO:0051310 7 5 0,000 0,01064595 0,06020383 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01064595 0,06006479 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01064595 0,0599264 ! enteric nervous system development GO:0048484 8 5 0,000 0,01064595 0,05978863 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01064595 0,0596515 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01064595 0,059515 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01064595 0,05937912 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01064595 0,05924386 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01064595 0,05910922 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01064595 0,05897518 ! B cell homeostasis GO:0001782 13 5 0,000 0,01064595 0,05884175 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01064595 0,05870893 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01064595 0,0585767 ! metaphase GO:0051323 11 5 0,000 0,01064595 0,05844507 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01064595 0,05831403 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01064595 0,05818357 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01064595 0,0580537 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01064595 0,0579244 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01064595 0,05779568 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01064595 0,05766753 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01064595 0,05753995 ! response to redox state GO:0051775 6 5 0,000 0,01064595 0,05741293 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01064595 0,05728647 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01064595 0,05716056 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01064595 0,05703521 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01064595 0,05691041 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01064595 0,05678615 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01064595 0,05666243 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01064595 0,05653925 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01064595 0,05641661 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01064595 0,05629449 ! striatum development GO:0021756 14 5 0,000 0,01064595 0,05617291 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01064595 0,05605184 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01064595 0,0559313 ! glial cell migration GO:0008347 10 5 0,000 0,01064595 0,05581128 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01064595 0,05569177 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01064595 0,05557277 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01064595 0,05545428 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01064595 0,05533629 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01064595 0,0552188 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01064595 0,05510181 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01064595 0,05498532 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01064595 0,05486932 ! neuroprotection GO:0043526 8 5 0,000 0,01064595 0,0547538 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01064595 0,05463877 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01064595 0,05452423 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01064595 0,05441016 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01064595 0,05429657 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01064595 0,05418345 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01064595 0,0540708 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01064595 0,05395862 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01064595 0,05384691 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01064595 0,05373565 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01064595 0,05362486 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01064595 0,05351452 ! spindle assembly GO:0051225 6 5 0,000 0,01064595 0,05340463 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01064595 0,0532952 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01064595 0,05318621 ! protein palmitoylation GO:0018345 12 5 0,000 0,01064595 0,05307766 ! drug metabolic process GO:0017144 7 5 0,000 0,01064595 0,05296956 ! stem cell division GO:0017145 11 5 0,000 0,01064595 0,0528619 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01064595 0,05275468 ! organ regeneration GO:0031100 7 5 0,000 0,01064595 0,05264789 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01064595 0,05254153 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01064595 0,0524356 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,01103276 0,05423146 ! respiratory system development GO:0060541 175 74 1,000 0,01103276 0,05412256 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,01131947 0,05541777 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01190268 0,05815649 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,01190268 0,05804041 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01190268 0,05792479 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01219915 0,05924954 ! protein oligomerization GO:0051259 149 79 1,000 0,01249884 0,06058466 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01276168 0,0617362 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01276168 0,06161419 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01276168 0,06149267 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01276168 0,06137162 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01276168 0,06125105 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01276168 0,06113095 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01276168 0,06101132 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01276168 0,06089215 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01276168 0,06077346 ! response to oxygen radical GO:0000305 11 6 0,000 0,01276168 0,06065522 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01276168 0,06053744 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01276168 0,06042012 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01276168 0,06030325 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01276168 0,06018684 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01276168 0,06007087 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01276168 0,05995535 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01276168 0,05984027 ! forebrain regionalization GO:0021871 9 6 0,000 0,01276168 0,05972564 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01276168 0,05961144 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01276168 0,05949768 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01276168 0,05938435 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01276168 0,05927145 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01276168 0,05915898 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01276168 0,05904694 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01276168 0,05893532 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01276168 0,05882412 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01276168 0,05871334 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01276168 0,05860297 ! malate metabolic process GO:0006108 13 6 0,000 0,01276168 0,05849303 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01276168 0,05838349 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01276168 0,05827436 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01276168 0,05816564 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01276168 0,05805732 ! protein refolding GO:0042026 15 6 0,000 0,01276168 0,05794941 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01276168 0,0578419 ! opsonization GO:0008228 8 6 0,000 0,01276168 0,05773478 ! mating behavior GO:0007617 7 6 0,000 0,01276168 0,05762806 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01276168 0,05752174 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01276168 0,05741581 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01276168 0,05731026 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01276168 0,05720511 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01276168 0,05710033 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01276168 0,05699595 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01276168 0,05689194 ! toxin metabolic process GO:0009404 11 6 0,000 0,01276168 0,05678831 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01276168 0,05668506 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01276168 0,05658218 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01276168 0,05647968 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01276168 0,05637755 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01276168 0,05627578 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01276168 0,05617438 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01276168 0,05607335 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01276168 0,05597268 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01276168 0,05587237 ! thymic T cell selection GO:0045061 16 6 0,000 0,01276168 0,05577242 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01276168 0,05567283 ! protein lipoylation GO:0009249 10 6 0,000 0,01276168 0,05557359 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01276168 0,0554747 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01276168 0,05537617 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01276168 0,05527798 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01276168 0,05518015 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01276168 0,05508265 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01276168 0,05498551 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01276168 0,0548887 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01276168 0,05479224 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01276168 0,05469611 ! hyperosmotic response GO:0006972 10 6 0,000 0,01276168 0,05460032 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01276168 0,05450486 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01276168 0,05440974 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01276168 0,05431495 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01276168 0,05422049 ! urea metabolic process GO:0019627 7 6 0,000 0,01276168 0,05412636 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01276168 0,05403255 ! neutrophil activation GO:0042119 7 6 0,000 0,01276168 0,05393907 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01276168 0,05384591 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01276168 0,05375307 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01276168 0,05366056 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01276168 0,05356836 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01276168 0,05347647 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01276168 0,0533849 ! neuron apoptosis GO:0051402 15 6 0,000 0,01276168 0,05329365 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01276168 0,0532027 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01276168 0,05311207 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01276168 0,05302174 ! carnitine transport GO:0015879 10 6 0,000 0,01276168 0,05293172 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01276168 0,052842 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01276168 0,05275259 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01276168 0,05266348 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01276168 0,05257468 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01276168 0,05248617 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01276168 0,05239795 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01276168 0,05231004 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01276168 0,05222242 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01276168 0,05213509 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01276168 0,05204805 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01276168 0,0519613 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01276168 0,05187485 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01276168 0,05178868 ! response to UV-C GO:0010225 14 6 0,000 0,01276168 0,05170279 ! astrocyte development GO:0014002 16 6 0,000 0,01276168 0,05161719 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01276168 0,05153187 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01276168 0,05144684 ! interaction with symbiont GO:0051702 14 6 0,000 0,01276168 0,05136208 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01276168 0,0512776 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01276168 0,0511934 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01276168 0,05110948 ! response to copper ion GO:0046688 10 6 0,000 0,01276168 0,05102583 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01276168 0,05094246 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01276168 0,05085935 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01276168 0,05077652 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01276168 0,05069396 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01276168 0,05061166 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01276168 0,05052963 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01276168 0,05044787 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01276168 0,05036637 ! Schwann cell development GO:0014044 15 6 0,000 0,01276168 0,05028513 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01276168 0,05020416 ! response to pheromone GO:0019236 6 6 0,000 0,01276168 0,05012344 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01276168 0,05004299 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01276168 0,04996279 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01276168 0,04988285 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01276168 0,04980317 ! subpallium development GO:0021544 15 6 0,000 0,01276168 0,04972374 ! neural tube patterning GO:0021532 8 6 0,000 0,01276168 0,04964456 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01276168 0,04956563 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01276168 0,04948696 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01276168 0,04940853 ! G2 phase GO:0051319 16 6 0,000 0,01276168 0,04933035 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01276168 0,04925242 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01276168 0,04917474 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01276168 0,0490973 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01276168 0,0490201 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01276168 0,04894314 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01276168 0,04886643 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01276168 0,04878996 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01276168 0,04871372 ! receptor internalization GO:0031623 11 6 0,000 0,01276168 0,04863773 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01276168 0,04856197 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01276168 0,04848644 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01276168 0,04841115 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01276168 0,0483361 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01276168 0,04826127 ! protein deubiquitination GO:0016579 16 6 0,000 0,01276168 0,04818668 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01276168 0,04811232 ! protein destabilization GO:0031648 9 6 0,000 0,01276168 0,04803819 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01276168 0,04796428 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01276168 0,0478906 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01276168 0,04781715 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01276168 0,04774392 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01276168 0,04767092 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01276168 0,04759814 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01276168 0,04752558 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01276168 0,04745325 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01276168 0,04738113 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01276168 0,04730923 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01276168 0,04723755 ! neural plate development GO:0001840 9 6 0,000 0,01276168 0,04716609 ! catecholamine transport GO:0051937 9 6 0,000 0,01276168 0,04709484 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01276168 0,0470238 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01276168 0,04695299 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01276168 0,04688238 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01276168 0,04681199 ! maternal placenta development GO:0001893 12 6 0,000 0,01276168 0,0467418 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01276168 0,04667183 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01276168 0,04660207 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01276168 0,04653251 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01276168 0,04646316 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01276168 0,04639402 ! muscle cell differentiation GO:0042692 178 81 1,000 0,01310784 0,04758166 ! response to hypoxia GO:0001666 178 81 1,000 0,01310784 0,04751106 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,01310784 0,04744067 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01341712 0,04848819 ! protein import into nucleus GO:0006606 174 82 1,000 0,01341712 0,04841656 ! response to oxygen levels GO:0070482 183 83 1,000 0,01372956 0,04947095 ! nuclear import GO:0051170 177 83 1,000 0,01372956 0,0493981 ! response to nutrient GO:0007584 135 84 1,000 0,01404515 0,05045926 ! negative regulation of transport GO:0051051 164 85 1,000 0,01436387 0,05152855 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01468572 0,05260589 GO:0002696|positive regulation of leukocyte activation, ! tRNA transcription GO:0009304 17 7 0,000 0,01487294 0,05319854 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01487294 0,05312076 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01487294 0,05304321 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01487294 0,05296589 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01487294 0,05288879 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01487294 0,05281192 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01487294 0,05273527 ! sleep GO:0030431 16 7 0,000 0,01487294 0,05265884 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01487294 0,05258264 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01487294 0,05250665 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01487294 0,05243088 ! prostate gland development GO:0030850 14 7 0,000 0,01487294 0,05235533 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01487294 0,05228 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01487294 0,05220489 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01487294 0,05212999 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01487294 0,0520553 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01487294 0,05198083 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01487294 0,05190657 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01487294 0,05183253 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01487294 0,05175869 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01487294 0,05168507 ! glycolipid transport GO:0046836 11 7 0,000 0,01487294 0,05161165 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01487294 0,05153844 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01487294 0,05146544 ! neuron adhesion GO:0007158 14 7 0,000 0,01487294 0,05139265 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01487294 0,05132006 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01487294 0,05124767 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01487294 0,05117549 ! mRNA stabilization GO:0048255 18 7 0,000 0,01487294 0,05110352 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01487294 0,05103174 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01487294 0,05096017 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01487294 0,0508888 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01487294 0,05081762 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01487294 0,05074665 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01487294 0,05067587 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01487294 0,05060529 ! lipoprotein transport GO:0042953 14 7 0,000 0,01487294 0,05053491 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01487294 0,05046472 ! rhythmic behavior GO:0007622 17 7 0,000 0,01487294 0,05039473 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01487294 0,05032493 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01487294 0,05025533 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01487294 0,05018591 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01487294 0,05011669 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01487294 0,05004766 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01487294 0,04997882 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01487294 0,04991017 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01487294 0,0498417 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01487294 0,04977343 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01487294 0,04970534 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01487294 0,04963743 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01487294 0,04956972 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01487294 0,04950218 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01487294 0,04943483 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01487294 0,04936767 ! spinal cord patterning GO:0021511 14 7 0,000 0,01487294 0,04930068 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01487294 0,04923388 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01487294 0,04916725 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01487294 0,04910081 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01487294 0,04903455 ! adrenal gland development GO:0030325 17 7 0,000 0,01487294 0,04896847 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01487294 0,04890256 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01487294 0,04883683 ! ovulation GO:0030728 10 7 0,000 0,01487294 0,04877128 ! adenohypophysis development GO:0021984 11 7 0,000 0,01487294 0,0487059 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01487294 0,0486407 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01487294 0,04857567 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01487294 0,04851082 ! microtubule nucleation GO:0007020 21 7 0,000 0,01487294 0,04844614 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01487294 0,04838163 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01487294 0,04831729 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01487294 0,04825312 ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01487294 0,04818913 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01487294 0,0481253 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01487294 0,04806164 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01487294 0,04799815 ! galactose metabolic process GO:0006012 13 7 0,000 0,01487294 0,04793483 ! response to dietary excess GO:0002021 8 7 0,000 0,01487294 0,04787168 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01487294 0,04780869 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01487294 0,04774586 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01487294 0,0476832 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01487294 0,04762071 ! organ growth GO:0035265 15 7 0,000 0,01487294 0,04755838 ! nucleoside transport GO:0015858 11 7 0,000 0,01487294 0,04749621 ! nucleoside salvage GO:0043174 11 7 0,000 0,01487294 0,04743421 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01487294 0,04737236 ! male sex determination GO:0030238 15 7 0,000 0,01487294 0,04731068 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01487294 0,04724916 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01487294 0,04718779 ! parturition GO:0007567 16 7 0,000 0,01487294 0,04712659 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01487294 0,04706555 ! rRNA modification GO:0000154 14 7 0,000 0,01487294 0,04700466 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01487294 0,04694393 ! spindle checkpoint GO:0031577 16 7 0,000 0,01487294 0,04688336 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01487294 0,04682294 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01487294 0,04676268 ! monocyte differentiation GO:0030224 16 7 0,000 0,01487294 0,04670257 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01487294 0,04664262 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01487294 0,04658282 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01487294 0,04652318 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01487294 0,04646368 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01487294 0,04640434 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01487294 0,04634515 ! fibrinolysis GO:0042730 11 7 0,000 0,01487294 0,04628612 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01487294 0,04622723 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01487294 0,04616849 ! eating behavior GO:0042755 8 7 0,000 0,01487294 0,0461099 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01487294 0,04605146 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01487294 0,04599317 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01487294 0,04593502 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01487294 0,04587702 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01487294 0,04581917 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01487294 0,04576146 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01487294 0,0457039 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01487294 0,04564648 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01487294 0,04558921 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01487294 0,04553208 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01487294 0,0454751 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01487294 0,04541825 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01487294 0,04536155 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01487294 0,04530499 ! histone ubiquitination GO:0016574 9 7 0,000 0,01487294 0,04524857 ! regulation of meiosis GO:0040020 12 7 0,000 0,01487294 0,04519229 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01487294 0,04513615 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01487294 0,04508015 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01487294 0,04502429 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01487294 0,04496857 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01487294 0,04491298 ! transcription termination GO:0006353 14 7 0,000 0,01487294 0,04485753 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01487294 0,04480222 ! anaphase GO:0051322 18 7 0,000 0,01487294 0,04474705 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01487294 0,04469201 ! axonal fasciculation GO:0007413 19 7 0,000 0,01487294 0,0446371 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01487294 0,04458233 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01487294 0,0445277 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01487294 0,0444732 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01487294 0,04441883 ! diuresis GO:0030146 12 7 0,000 0,01487294 0,04436459 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01487294 0,04431049 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01487294 0,04425652 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01487294 0,04420268 ! antibiotic transport GO:0042891 9 7 0,000 0,01487294 0,04414897 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01487294 0,04409539 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01487294 0,04404194 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01487294 0,04398862 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01487294 0,04393543 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01487294 0,04388237 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01487294 0,04382943 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01487294 0,04377663 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01487294 0,04372395 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01487294 0,0436714 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01487294 0,04361897 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01487294 0,04356667 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01487294 0,04351449 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01487294 0,04346244 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01487294 0,04341052 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01487294 0,04335871 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01487294 0,04330703 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01487294 0,04325548 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01487294 0,04320404 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01487294 0,04315273 ! muscle adaptation GO:0043500 13 7 0,000 0,01487294 0,04310154 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01487294 0,04305048 ! retina homeostasis GO:0001895 12 7 0,000 0,01487294 0,04299953 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01487294 0,0429487 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01487294 0,04289799 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01487294 0,04284741 ! mitochondrion organization GO:0007005 159 87 1,000 0,01501068 0,04319327 ! alcohol catabolic process GO:0046164 142 87 1,000 0,01501068 0,04314245 ! regulation of protein transport GO:0051223 165 87 1,000 0,01501068 0,04309175 GO:0070201|regulation of establishment of protein localization, ! tube morphogenesis GO:0035239 194 89 1,000 0,01566985 0,04493127 ! protein localization in nucleus GO:0034504 192 89 1,000 0,01566985 0,0448786 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,01600404 0,04578204 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,01600404 0,0457285 ! ossification GO:0001503 205 91 1,000 0,01634128 0,04663755 ! gland development GO:0048732 220 91 1,000 0,01634128 0,04658313 ! defense response to bacterium GO:0042742 112 91 1,000 0,01634128 0,04652884 ! bone development GO:0060348 206 92 1,000 0,01668155 0,04744241 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,01668155 0,04738724 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01697975 0,04817832 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01697975 0,04812243 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01697975 0,04806667 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01697975 0,04801104 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01697975 0,04795553 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01697975 0,04790016 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01697975 0,04784491 ! male meiosis GO:0007140 9 8 0,000 0,01697975 0,04778979 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01697975 0,04773479 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01697975 0,04767993 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01697975 0,04762518 ! meiotic prophase I GO:0007128 14 8 0,000 0,01697975 0,04757057 ! response to zinc ion GO:0010043 12 8 0,000 0,01697975 0,04751608 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01697975 0,04746171 ! oligopeptide transport GO:0006857 16 8 0,000 0,01697975 0,04740747 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01697975 0,04735335 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01697975 0,04729936 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01697975 0,04724548 ! signal peptide processing GO:0006465 12 8 0,000 0,01697975 0,04719173 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01697975 0,04713811 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01697975 0,0470846 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01697975 0,04703122 ! succinate metabolic process GO:0006105 17 8 0,000 0,01697975 0,04697796 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01697975 0,04692481 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01697975 0,04687179 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01697975 0,04681889 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01697975 0,0467661 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01697975 0,04671344 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01697975 0,04666089 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01697975 0,04660847 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01697975 0,04655616 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01697975 0,04650396 ! reflex GO:0060004 17 8 0,000 0,01697975 0,04645189 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01697975 0,04639993 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01697975 0,04634808 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01697975 0,04629636 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01697975 0,04624474 ! pigment granule organization GO:0048753 17 8 0,000 0,01697975 0,04619325 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01697975 0,04614186 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01697975 0,04609059 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01697975 0,04603944 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01697975 0,0459884 ! histidine catabolic process GO:0006548 10 8 0,000 0,01697975 0,04593747 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01697975 0,04588665 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01697975 0,04583595 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01697975 0,04578536 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01697975 0,04573488 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01697975 0,04568451 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01697975 0,04563425 ! melanin metabolic process GO:0006582 17 8 0,000 0,01697975 0,0455841 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01697975 0,04553407 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01697975 0,04548414 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01697975 0,04543432 ! macrophage activation GO:0042116 13 8 0,000 0,01697975 0,04538461 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01697975 0,04533501 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01697975 0,04528552 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01697975 0,04523613 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01697975 0,04518686 ! purine salvage GO:0043101 12 8 0,000 0,01697975 0,04513769 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01697975 0,04508862 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01697975 0,04503967 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01697975 0,04499082 ! osteoblast development GO:0002076 17 8 0,000 0,01697975 0,04494207 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01697975 0,04489344 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01697975 0,0448449 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01697975 0,04479647 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01697975 0,04474815 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01697975 0,04469993 ! response to UV-B GO:0010224 17 8 0,000 0,01697975 0,04465181 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01697975 0,0446038 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01697975 0,04455589 ! intermediate filament organization GO:0045109 12 8 0,000 0,01697975 0,04450808 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01697975 0,04446038 ! cellular extravasation GO:0045123 13 8 0,000 0,01697975 0,04441278 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01697975 0,04436528 ! response to antibiotic GO:0046677 11 8 0,000 0,01697975 0,04431788 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01697975 0,04427058 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01697975 0,04422338 ! DNA topological change GO:0006265 12 8 0,000 0,01697975 0,04417629 ! response to tropane GO:0014073 15 8 0,000 0,01697975 0,04412929 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01697975 0,0440824 ! melanosome transport GO:0032402 13 8 0,000 0,01697975 0,0440356 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01697975 0,0439889 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01697975 0,0439423 ! mast cell activation GO:0045576 14 8 0,000 0,01697975 0,0438958 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01697975 0,0438494 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01697975 0,0438031 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01697975 0,04375689 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01697975 0,04371078 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01697975 0,04366477 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01697975 0,04361886 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01697975 0,04357304 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01697975 0,04352732 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01697975 0,04348169 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01697975 0,04343616 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01697975 0,04339073 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01697975 0,04334539 ! response to tumor cell GO:0002347 16 8 0,000 0,01697975 0,04330014 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01697975 0,04325499 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01697975 0,04320993 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01697975 0,04316497 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01697975 0,0431201 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01697975 0,04307532 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01697975 0,04303064 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01697975 0,04298605 ! hormone catabolic process GO:0042447 17 8 0,000 0,01697975 0,04294155 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01697975 0,04289714 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01697975 0,04285283 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01697975 0,0428086 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01697975 0,04276447 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01697975 0,04272043 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01697975 0,04267648 ! adult feeding behavior GO:0008343 10 8 0,000 0,01697975 0,04263262 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01697975 0,04258884 ! ATP catabolic process GO:0006200 11 8 0,000 0,01697975 0,04254516 ! blastocyst growth GO:0001832 19 8 0,000 0,01697975 0,04250157 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01697975 0,04245807 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01697975 0,04241466 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01697975 0,04237133 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01697975 0,0423281 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01697975 0,04228495 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01697975 0,04224189 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01697975 0,04219892 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01697975 0,04215603 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01697975 0,04211323 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01697975 0,04207052 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01697975 0,0420279 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01697975 0,04198536 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01697975 0,04194291 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01697975 0,04190054 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01697975 0,04185826 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01697975 0,04181606 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,01737115 0,04273688 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01737115 0,04269388 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01772044 0,04350859 ! transcription initiation GO:0006352 171 97 1,000 0,01842796 0,0452003 ! regulation of protein localization GO:0032880 188 97 1,000 0,01842796 0,04515497 ! axon extension GO:0048675 16 9 0,000 0,01908211 0,04671103 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01908211 0,04666427 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01908211 0,04661761 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01908211 0,04657103 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01908211 0,04652456 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01908211 0,04647817 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01908211 0,04643188 ! reproductive behavior GO:0019098 22 9 0,000 0,01908211 0,04638568 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01908211 0,04633957 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01908211 0,04629355 ! UTP metabolic process GO:0046051 10 9 0,000 0,01908211 0,04624762 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01908211 0,04620179 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01908211 0,04615604 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01908211 0,04611039 ! artery development GO:0060840 25 9 0,000 0,01908211 0,04606483 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01908211 0,04601935 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01908211 0,04597397 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01908211 0,04592868 ! equilibrioception GO:0050957 20 9 0,000 0,01908211 0,04588347 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01908211 0,04583835 ! chemosensory behavior GO:0007635 21 9 0,000 0,01908211 0,04579333 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01908211 0,04574839 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01908211 0,04570353 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01908211 0,04565877 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01908211 0,0456141 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01908211 0,04556951 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01908211 0,04552501 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01908211 0,04548059 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01908211 0,04543626 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01908211 0,04539202 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01908211 0,04534787 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01908211 0,0453038 ! protein targeting to ER GO:0045047 25 9 0,000 0,01908211 0,04525981 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01908211 0,04521591 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01908211 0,0451721 ! T cell selection GO:0045058 27 9 0,000 0,01908211 0,04512837 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01908211 0,04508472 ! glycine catabolic process GO:0006546 15 9 0,000 0,01908211 0,04504116 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01908211 0,04499769 ! endosome organization GO:0007032 20 9 0,000 0,01908211 0,0449543 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01908211 0,04491099 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01908211 0,04486776 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01908211 0,04482462 ! mannose metabolic process GO:0006013 13 9 0,000 0,01908211 0,04478156 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01908211 0,04473858 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01908211 0,04469569 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01908211 0,04465288 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01908211 0,04461015 ! receptor clustering GO:0043113 20 9 0,000 0,01908211 0,0445675 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01908211 0,04452493 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01908211 0,04448245 ! retinol metabolic process GO:0042572 20 9 0,000 0,01908211 0,04444004 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01908211 0,04439772 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01908211 0,04435548 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01908211 0,04431331 ! macrophage differentiation GO:0030225 15 9 0,000 0,01908211 0,04427123 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01908211 0,04422923 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01908211 0,0441873 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01908211 0,04414546 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01908211 0,04410369 ! response to amine stimulus GO:0014075 13 9 0,000 0,01908211 0,04406201 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01908211 0,0440204 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01908211 0,04397887 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01908211 0,04393742 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01908211 0,04389605 ! renal water homeostasis GO:0003091 15 9 0,000 0,01908211 0,04385476 ! postreplication repair GO:0006301 25 9 0,000 0,01908211 0,04381354 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01908211 0,0437724 ! icosanoid secretion GO:0032309 15 9 0,000 0,01908211 0,04373134 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01908211 0,04369035 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01908211 0,04364944 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01908211 0,04360861 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01908211 0,04356786 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01908211 0,04352718 ! sterol catabolic process GO:0016127 14 9 0,000 0,01908211 0,04348657 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01908211 0,04344604 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01908211 0,04340559 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01908211 0,04336521 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01908211 0,04332491 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01908211 0,04328468 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01908211 0,04324453 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01908211 0,04320445 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01908211 0,04316445 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01908211 0,04312452 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01908211 0,04308466 ! purine base metabolic process GO:0006144 25 9 0,000 0,01908211 0,04304488 ! pigment granule transport GO:0051904 17 9 0,000 0,01908211 0,04300517 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01908211 0,04296553 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01908211 0,04292597 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01908211 0,04288648 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01908211 0,04284706 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01908211 0,04280772 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01908211 0,04276845 ! mitochondrion localization GO:0051646 18 9 0,000 0,01908211 0,04272924 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,01951133 0,04365034 GO:0060538|skeletal muscle organ development, ! regulation of developmental growth GO:0048638 16 10 0,000 0,02118004 0,0473402 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02118004 0,04729692 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02118004 0,04725373 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02118004 0,04721062 ! associative learning GO:0008306 21 10 0,000 0,02118004 0,04716758 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02118004 0,04712462 ! phosphate transport GO:0006817 24 10 0,000 0,02118004 0,04708174 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02118004 0,04703894 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02118004 0,04699622 ! CTP metabolic process GO:0046036 11 10 0,000 0,02118004 0,04695357 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02118004 0,046911 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02118004 0,04686851 ! GTP metabolic process GO:0046039 11 10 0,000 0,02118004 0,0468261 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02118004 0,04678376 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02118004 0,0467415 ! social behavior GO:0035176 29 10 0,000 0,02118004 0,04669931 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02118004 0,0466572 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02118004 0,04661517 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02118004 0,04657321 ! androgen metabolic process GO:0008209 17 10 0,000 0,02118004 0,04653133 ! phospholipid efflux GO:0033700 19 10 0,000 0,02118004 0,04648952 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02118004 0,04644779 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02118004 0,04640613 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02118004 0,04636455 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02118004 0,04632304 ! lung alveolus development GO:0048286 26 10 0,000 0,02118004 0,04628161 ! pathogenesis GO:0009405 17 10 0,000 0,02118004 0,04624025 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02118004 0,04619896 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02118004 0,04615775 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02118004 0,04611661 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02118004 0,04607554 ! endoderm development GO:0007492 18 10 0,000 0,02118004 0,04603455 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02118004 0,04599363 ! arginine catabolic process GO:0006527 17 10 0,000 0,02118004 0,04595278 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02118004 0,04591201 ! proline metabolic process GO:0006560 13 10 0,000 0,02118004 0,04587131 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02118004 0,04583068 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02118004 0,04579012 ! V(D)J recombination GO:0033151 34 10 0,000 0,02118004 0,04574963 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02118004 0,04570922 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02118004 0,04566888 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02118004 0,0456286 ! B cell proliferation GO:0042100 19 10 0,000 0,02118004 0,0455884 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02118004 0,04554827 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02118004 0,04550821 ! multicellular organism growth GO:0035264 19 10 0,000 0,02118004 0,04546822 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02118004 0,0454283 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02118004 0,04538845 ! ruffle organization GO:0031529 17 10 0,000 0,02118004 0,04534867 ! epithelial cell development GO:0002064 21 10 0,000 0,02118004 0,04530896 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02118004 0,04526932 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02118004 0,04522975 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02118004 0,04519025 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02118004 0,04515082 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02118004 0,04511145 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02118004 0,04507216 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02118004 0,04503293 ! motor axon guidance GO:0008045 22 10 0,000 0,02118004 0,04499377 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02118004 0,04495468 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02118004 0,04491566 ! protein heterooligomerization GO:0051291 17 10 0,000 0,02118004 0,0448767 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02118004 0,04483781 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02118004 0,04479899 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02118004 0,04476024 ! segment specification GO:0007379 15 10 0,000 0,02118004 0,04472155 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02118004 0,04468293 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02118004 0,04464438 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02118004 0,04460589 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02118004 0,04456747 ! response to dsRNA GO:0043331 23 10 0,000 0,02118004 0,04452912 ! DNA ligation GO:0006266 18 10 0,000 0,02118004 0,04449083 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02118004 0,04445261 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02118004 0,04441445 ! melanosome localization GO:0032400 16 10 0,000 0,02118004 0,04437636 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02118004 0,04433833 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02118004 0,04430037 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02118004 0,04426248 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02118004 0,04422465 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02118004 0,04418688 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02118004 0,04414918 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02118004 0,04411154 ! protein sumoylation GO:0016925 17 10 0,000 0,02118004 0,04407397 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02118004 0,04403646 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02118004 0,04399901 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02118004 0,04396163 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02118004 0,04392431 ! salivary gland development GO:0007431 28 10 0,000 0,02118004 0,04388705 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02118004 0,04384986 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02118004 0,04381273 ! midbrain development GO:0030901 14 10 0,000 0,02118004 0,04377566 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02118004 0,04373866 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02118004 0,04370172 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02118004 0,04366484 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02118004 0,04362802 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02118004 0,04359127 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02118004 0,04355458 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02118004 0,04351794 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02118004 0,04348137 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02118004 0,04344487 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,02118004 0,04340842 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,02118004 0,04337203 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02118004 0,04333571 ! blastocyst formation GO:0001825 18 10 0,000 0,02118004 0,04329944 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02118004 0,04326324 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02118004 0,0432271 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02118004 0,04319101 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02118004 0,04315499 ! response to nicotine GO:0035094 20 10 0,000 0,02118004 0,04311903 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02118004 0,04308313 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02118004 0,04304728 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02327354 0,04726288 ! respiratory burst GO:0045730 17 11 0,000 0,02327354 0,04722363 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02327354 0,04718444 ! neuron fate specification GO:0048665 18 11 0,000 0,02327354 0,04714531 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02327354 0,04710625 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02327354 0,04706726 ! thyroid gland development GO:0030878 26 11 0,000 0,02327354 0,04702833 ! synapsis GO:0007129 14 11 0,000 0,02327354 0,04698946 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02327354 0,04695066 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02327354 0,04691192 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02327354 0,04687325 ! response to pain GO:0048265 27 11 0,000 0,02327354 0,04683464 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02327354 0,04679609 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02327354 0,04675761 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02327354 0,04671919 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02327354 0,04668083 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02327354 0,04664253 ! bone resorption GO:0045453 16 11 0,000 0,02327354 0,0466043 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02327354 0,04656613 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02327354 0,04652803 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02327354 0,04648998 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02327354 0,046452 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02327354 0,04641408 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02327354 0,04637622 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02327354 0,04633843 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02327354 0,04630069 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02327354 0,04626302 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02327354 0,04622541 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02327354 0,04618785 ! UV protection GO:0009650 20 11 0,000 0,02327354 0,04615036 ! adult heart development GO:0007512 16 11 0,000 0,02327354 0,04611293 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02327354 0,04607557 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02327354 0,04603826 ! macroautophagy GO:0016236 19 11 0,000 0,02327354 0,04600101 ! temperature homeostasis GO:0001659 18 11 0,000 0,02327354 0,04596382 ! behavioral fear response GO:0001662 27 11 0,000 0,02327354 0,0459267 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02327354 0,04588963 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02327354 0,04585262 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02327354 0,04581567 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02327354 0,04577878 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02327354 0,04574195 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02327354 0,04570518 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02327354 0,04566847 ! regulation of organ growth GO:0046620 14 11 0,000 0,02327354 0,04563182 ! pigment granule localization GO:0051875 20 11 0,000 0,02327354 0,04559523 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02327354 0,04555869 ! vasoconstriction GO:0042310 20 11 0,000 0,02327354 0,04552222 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02327354 0,0454858 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02327354 0,04544944 ! embryonic axis specification GO:0000578 19 11 0,000 0,02327354 0,04541314 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02327354 0,04537689 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02327354 0,04534071 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02327354 0,04530458 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02327354 0,04526851 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02327354 0,0452325 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02327354 0,04519654 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02327354 0,04516064 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02327354 0,0451248 ! prophase GO:0051324 17 11 0,000 0,02327354 0,04508902 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02327354 0,04505329 ! nucleosome positioning GO:0016584 15 11 0,000 0,02327354 0,04501762 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02327354 0,044982 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02327354 0,04494644 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02327354 0,04491094 ! apical protein localization GO:0045176 18 11 0,000 0,02327354 0,04487549 ! acid secretion GO:0046717 20 11 0,000 0,02327354 0,0448401 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02327354 0,04480477 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02327354 0,04476949 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02327354 0,04473426 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02327354 0,04469909 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02327354 0,04466398 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02327354 0,04462892 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02327354 0,04459392 ! cholesterol efflux GO:0033344 21 11 0,000 0,02327354 0,04455897 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02327354 0,04452408 ! oocyte development GO:0048599 20 11 0,000 0,02327354 0,04448924 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02327354 0,04445446 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02327354 0,04441973 ! embryonic gut development GO:0048566 19 11 0,000 0,02327354 0,04438505 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02327354 0,04435043 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02327354 0,04431586 ! activation of innate immune response GO:0002218 16 11 0,000 0,02327354 0,04428135 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02327354 0,04424689 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02327354 0,04421248 ! lysogeny GO:0030069 22 11 0,000 0,02327354 0,04417813 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02327354 0,04414383 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02327354 0,04410958 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02327354 0,04407539 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02327354 0,04404125 ! nucleus localization GO:0051647 22 11 0,000 0,02327354 0,04400716 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02536261 0,04792024 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02536261 0,0478832 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02536261 0,04784623 ! virus-host interaction GO:0019048 30 12 0,000 0,02536261 0,04780931 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02536261 0,04777245 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02536261 0,04773564 ! protein complex disassembly GO:0043241 28 12 0,000 0,02536261 0,0476989 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02536261 0,0476622 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02536261 0,04762557 ! hippocampus development GO:0021766 29 12 0,000 0,02536261 0,04758899 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02536261 0,04755247 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02536261 0,047516 ! T cell proliferation GO:0042098 32 12 0,000 0,02536261 0,04747959 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02536261 0,04744324 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02536261 0,04740694 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02536261 0,04737069 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02536261 0,0473345 ! drug transport GO:0015893 16 12 0,000 0,02536261 0,04729837 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02536261 0,04726229 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02536261 0,04722627 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02536261 0,0471903 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02536261 0,04715439 ! focal adhesion formation GO:0048041 37 12 0,000 0,02536261 0,04711853 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02536261 0,04708273 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02536261 0,04704698 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02536261 0,04701128 ! lipid digestion GO:0044241 21 12 0,000 0,02536261 0,04697564 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02536261 0,04694005 ! entry into host cell GO:0030260 34 12 0,000 0,02536261 0,04690452 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02536261 0,04686904 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02536261 0,04683361 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02536261 0,04679824 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02536261 0,04676292 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02536261 0,04672765 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02536261 0,04669244 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02536261 0,04665728 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02536261 0,04662217 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02536261 0,04658712 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02536261 0,04655212 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02536261 0,04651717 ! cranial nerve development GO:0021545 23 12 0,000 0,02536261 0,04648227 ! fucose catabolic process GO:0019317 25 12 0,000 0,02536261 0,04644743 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02536261 0,04641263 ! histone acetylation GO:0016573 27 12 0,000 0,02536261 0,04637789 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02536261 0,04634321 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02536261 0,04630857 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02536261 0,04627399 ! zymogen activation GO:0031638 18 12 0,000 0,02536261 0,04623945 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02536261 0,04620497 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02536261 0,04617054 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02536261 0,04613616 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02536261 0,04610184 ! oocyte differentiation GO:0009994 21 12 0,000 0,02536261 0,04606756 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02536261 0,04603333 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02536261 0,04599916 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02536261 0,04596503 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02536261 0,04593096 ! defense response to fungus GO:0050832 15 12 0,000 0,02536261 0,04589694 ! embryonic placenta development GO:0001892 21 12 0,000 0,02536261 0,04586297 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02536261 0,04582904 ! response to cold GO:0009409 17 12 0,000 0,02536261 0,04579517 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02536261 0,04576135 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02536261 0,04572758 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02744728 0,04944964 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02744728 0,0494132 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02744728 0,04937681 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02744728 0,04934048 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02744728 0,0493042 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02744728 0,04926797 ! peroxisomal transport GO:0043574 28 13 0,000 0,02744728 0,0492318 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02744728 0,04919568 ! cartilage condensation GO:0001502 22 13 0,000 0,02744728 0,04915961 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02744728 0,0491236 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02744728 0,04908764 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02744728 0,04905173 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02744728 0,04901587 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02744728 0,04898007 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02744728 0,04894431 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02744728 0,04890862 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02744728 0,04887297 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02744728 0,04883737 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02744728 0,04880183 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02744728 0,04876634 ! methionine metabolic process GO:0006555 31 13 0,000 0,02744728 0,04873089 ! plasma membrane organization GO:0007009 27 13 0,000 0,02744728 0,04869551 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02744728 0,04866017 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02744728 0,04862488 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02744728 0,04858965 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02744728 0,04855446 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02744728 0,04851933 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02744728 0,04848425 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02744728 0,04844921 ! exocrine system development GO:0035272 34 13 0,000 0,02744728 0,04841423 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02744728 0,0483793 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02744728 0,04834442 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02744728 0,04830959 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02744728 0,04827481 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02744728 0,04824008 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02744728 0,0482054 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02744728 0,04817077 ! protein homotetramerization GO:0051289 24 13 0,000 0,02744728 0,04813619 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02744728 0,04810166 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02744728 0,04806718 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02744728 0,04803274 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02744728 0,04799836 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02744728 0,04796403 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02744728 0,04792974 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02744728 0,04789551 ! histone methylation GO:0016571 29 13 0,000 0,02744728 0,04786132 ! chromatin silencing GO:0006342 29 13 0,000 0,02744728 0,04782718 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02744728 0,04779309 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02744728 0,04775905 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02744728 0,04772506 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02744728 0,04769112 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02744728 0,04765722 ! spleen development GO:0048536 24 13 0,000 0,02744728 0,04762337 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02744728 0,04758958 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02744728 0,04755582 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02744728 0,04752212 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02744728 0,04748846 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02744728 0,04745486 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02744728 0,0474213 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02744728 0,04738778 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02744728 0,04735432 ! insulin secretion GO:0030073 24 13 0,000 0,02744728 0,0473209 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02744728 0,04728753 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02744728 0,0472542 ! acrosome reaction GO:0007340 19 13 0,000 0,02744728 0,04722092 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02744728 0,04718769 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02744728 0,04715451 ! rRNA transcription GO:0009303 28 14 0,000 0,02952755 0,05069277 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02952755 0,05065717 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02952755 0,05062162 ! water transport GO:0006833 21 14 0,000 0,02952755 0,05058612 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02952755 0,05055067 ! non-recombinational repair GO:0000726 29 14 0,000 0,02952755 0,05051527 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02952755 0,05047992 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02952755 0,05044462 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02952755 0,05040937 ! palate development GO:0060021 32 14 0,000 0,02952755 0,05037417 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02952755 0,05033901 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02952755 0,05030391 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02952755 0,05026885 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02952755 0,05023385 ! arginine metabolic process GO:0006525 21 14 0,000 0,02952755 0,05019889 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02952755 0,05016398 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02952755 0,05012912 ! regulation of heart rate GO:0002027 25 14 0,000 0,02952755 0,05009431 ! fear response GO:0042596 34 14 0,000 0,02952755 0,05005955 ! organic alcohol transport GO:0015850 29 14 0,000 0,02952755 0,05002483 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02952755 0,04999016 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02952755 0,04995554 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02952755 0,04992097 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02952755 0,04988645 ! bone mineralization GO:0030282 18 14 0,000 0,02952755 0,04985197 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02952755 0,04981755 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02952755 0,04978317 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02952755 0,04974883 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02952755 0,04971455 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02952755 0,04968031 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02952755 0,04964612 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02952755 0,04961197 ! ribosome assembly GO:0042255 18 14 0,000 0,02952755 0,04957787 ! cerebellum development GO:0021549 23 14 0,000 0,02952755 0,04954382 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02952755 0,04950982 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02952755 0,04947586 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02952755 0,04944195 ! response to gamma radiation GO:0010332 30 14 0,000 0,02952755 0,04940809 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02952755 0,04937427 ! NADP metabolic process GO:0006739 24 14 0,000 0,02952755 0,0493405 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02952755 0,04930677 ! oxygen transport GO:0015671 22 14 0,000 0,02952755 0,04927309 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02952755 0,04923946 ! male genitalia development GO:0030539 26 14 0,000 0,02952755 0,04920587 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02952755 0,04917233 ! regulation of axon extension GO:0030516 43 14 0,000 0,02952755 0,04913883 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02952755 0,04910538 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02952755 0,04907198 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03160343 0,05248618 ! lactation GO:0007595 30 15 0,000 0,03160343 0,05245053 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,03160343 0,05241492 ! reproductive cellular process GO:0048610 22 15 0,000 0,03160343 0,05237936 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03160343 0,05234385 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03160343 0,05230838 ! superoxide anion generation GO:0042554 22 15 0,000 0,03160343 0,05227297 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03160343 0,0522376 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03160343 0,05220228 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03160343 0,05216701 ! copper ion transport GO:0006825 22 15 0,000 0,03160343 0,05213179 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03160343 0,05209661 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03160343 0,05206148 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03160343 0,0520264 ! sulfate transport GO:0008272 27 15 0,000 0,03160343 0,05199136 ! response to cAMP GO:0051591 25 15 0,000 0,03160343 0,05195638 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03160343 0,05192143 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03160343 0,05188654 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03160343 0,05185169 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03160343 0,0518169 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03160343 0,05178214 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03160343 0,05174744 ! vesicle coating GO:0006901 38 15 0,000 0,03160343 0,05171278 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03160343 0,05167816 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03160343 0,05164359 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,03160343 0,05160907 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03160343 0,0515746 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03160343 0,05154017 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03160343 0,05150579 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03160343 0,05147145 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03160343 0,05143716 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03160343 0,05140291 ! histone deacetylation GO:0016575 24 15 0,000 0,03160343 0,05136871 ! water homeostasis GO:0030104 28 15 0,000 0,03160343 0,05133456 ! cofactor transport GO:0051181 30 15 0,000 0,03160343 0,05130045 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03160343 0,05126638 ! muscle maintenance GO:0046716 26 15 0,000 0,03160343 0,05123236 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03160343 0,05119839 ! intestinal absorption GO:0050892 31 15 0,000 0,03160343 0,05116446 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03160343 0,05113058 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03160343 0,05109674 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03160343 0,05106295 ! cell killing GO:0001906 32 15 0,000 0,03160343 0,0510292 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03160343 0,05099549 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03160343 0,05096183 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03160343 0,05092821 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03160343 0,05089464 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03160343 0,05086112 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03367492 0,05415921 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03367492 0,05412358 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03367492 0,05408799 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03367492 0,05405245 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03367492 0,05401696 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03367492 0,05398152 ! bone remodeling GO:0046849 28 16 0,000 0,03367492 0,05394612 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03367492 0,05391077 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03367492 0,05387547 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03367492 0,05384021 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03367492 0,05380499 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03367492 0,05376983 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03367492 0,05373471 ! startle response GO:0001964 28 16 0,000 0,03367492 0,05369963 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03367492 0,0536646 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03367492 0,05362962 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03367492 0,05359468 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03367492 0,05355979 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03367492 0,05352494 ! pituitary gland development GO:0021983 30 16 0,000 0,03367492 0,05349014 ! response to osmotic stress GO:0006970 27 16 0,000 0,03367492 0,05345538 ! lysosomal transport GO:0007041 31 16 0,000 0,03367492 0,05342067 ! fructose metabolic process GO:0006000 25 16 0,000 0,03367492 0,05338601 ! L-amino acid transport GO:0015807 33 16 0,000 0,03367492 0,05335138 ! stem cell development GO:0048864 46 16 0,000 0,03367492 0,05331681 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03367492 0,05328228 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03367492 0,05324779 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03367492 0,05321335 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03367492 0,05317895 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03367492 0,0531446 ! axon cargo transport GO:0008088 46 16 0,000 0,03367492 0,05311029 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03367492 0,05307602 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03367492 0,0530418 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03367492 0,05300763 ! neuron recognition GO:0008038 40 16 0,000 0,03367492 0,05297349 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03367492 0,05293941 ! tissue regeneration GO:0042246 27 16 0,000 0,03367492 0,05290536 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03367492 0,05287136 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03367492 0,0528374 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03367492 0,05280349 ! biomineral formation GO:0031214 22 16 0,000 0,03367492 0,05276962 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03367492 0,05273579 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03367492 0,05270201 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03367492 0,05266827 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03367492 0,05263457 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03367492 0,05260092 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03367492 0,05256731 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03367492 0,05253374 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03367492 0,05250021 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03367492 0,05246673 ! peptide hormone processing GO:0016486 27 16 0,000 0,03367492 0,05243329 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03574204 0,05561644 ! metencephalon development GO:0022037 32 17 0,000 0,03574204 0,05558104 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03574204 0,05554568 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03574204 0,05551037 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03574204 0,0554751 ! signal complex assembly GO:0007172 47 17 0,000 0,03574204 0,05543988 ! filopodium assembly GO:0046847 42 17 0,000 0,03574204 0,0554047 ! endothelial cell migration GO:0043542 31 17 0,000 0,03574204 0,05536957 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03574204 0,05533448 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03574204 0,05529944 ! glial cell development GO:0021782 28 17 0,000 0,03574204 0,05526444 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03574204 0,05522948 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03574204 0,05519457 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03574204 0,05515971 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03574204 0,05512488 ! myoblast differentiation GO:0045445 50 17 0,000 0,03574204 0,0550901 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03574204 0,05505537 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03574204 0,05502068 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03574204 0,05498603 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03574204 0,05495142 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03574204 0,05491686 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03574204 0,05488235 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03574204 0,05484787 ! membrane budding GO:0006900 42 17 0,000 0,03574204 0,05481344 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03574204 0,05477906 ! regulation of protein binding GO:0043393 33 17 0,000 0,03574204 0,05474471 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03574204 0,05471041 ! genitalia development GO:0048806 32 17 0,000 0,03574204 0,05467615 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03574204 0,05464194 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03574204 0,05460776 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03574204 0,05457363 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03574204 0,05453955 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03574204 0,0545055 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03574204 0,0544715 ! steroid catabolic process GO:0006706 34 17 0,000 0,03574204 0,05443754 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03574204 0,05440362 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03574204 0,05436975 ! gas transport GO:0015669 26 17 0,000 0,03574204 0,05433591 ! organic cation transport GO:0015695 32 17 0,000 0,03574204 0,05430212 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03574204 0,05426837 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03574204 0,05423467 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03574204 0,054201 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0378048 0,05729351 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0378048 0,05725799 ! limbic system development GO:0021761 40 18 0,000 0,0378048 0,05722251 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0378048 0,05718708 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0378048 0,05715169 ! adult walking behavior GO:0007628 36 18 0,000 0,0378048 0,05711635 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0378048 0,05708105 ! heart looping GO:0001947 34 18 0,000 0,0378048 0,05704579 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0378048 0,05701058 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0378048 0,05697541 ! centrosome cycle GO:0007098 26 18 0,000 0,0378048 0,05694028 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0378048 0,0569052 ! glycine metabolic process GO:0006544 30 18 0,000 0,0378048 0,05687016 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0378048 0,05683516 ! response to retinoic acid GO:0032526 31 18 0,000 0,0378048 0,0568002 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,0378048 0,05676529 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0378048 0,05673043 ! DNA integration GO:0015074 32 18 0,000 0,0378048 0,0566956 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,0378048 0,05666082 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0378048 0,05662608 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0378048 0,05659138 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0378048 0,05655673 ! neural crest cell migration GO:0001755 41 18 0,000 0,0378048 0,05652211 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0378048 0,05648754 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0378048 0,05645301 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0378048 0,05641853 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0378048 0,05638409 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0378048 0,05634968 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0378048 0,05631532 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,0378048 0,05628101 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0378048 0,05624673 ! detection of bacterium GO:0016045 22 18 0,000 0,0378048 0,0562125 ! nerve development GO:0021675 34 18 0,000 0,0378048 0,0561783 ! defense response to virus GO:0051607 43 18 0,000 0,0378048 0,05614415 ! microspike assembly GO:0030035 46 18 0,000 0,0378048 0,05611004 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0378048 0,05607598 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,0378048 0,05604195 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03986321 0,0590575 ! positive regulation of translation GO:0045727 31 19 0,000 0,03986321 0,0590217 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03986321 0,05898595 ! neuron maturation GO:0042551 46 19 0,000 0,03986321 0,05895025 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03986321 0,05891459 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03986321 0,05887897 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03986321 0,05884339 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03986321 0,05880786 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03986321 0,05877237 ! inositol metabolic process GO:0006020 33 19 0,000 0,03986321 0,05873692 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03986321 0,05870151 ! memory GO:0007613 34 19 0,000 0,03986321 0,05866615 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03986321 0,05863083 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03986321 0,05859555 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03986321 0,05856032 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03986321 0,05852513 ! cerebral cortex development GO:0021987 40 19 0,000 0,03986321 0,05848998 ! pigmentation during development GO:0048066 42 19 0,000 0,03986321 0,05845487 ! response to vitamin A GO:0033189 32 19 0,000 0,03986321 0,0584198 ! heme metabolic process GO:0042168 40 19 0,000 0,03986321 0,05838478 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03986321 0,0583498 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03986321 0,05831486 ! response to fungus GO:0009620 26 19 0,000 0,03986321 0,05827996 ! peptide cross-linking GO:0018149 39 19 0,000 0,03986321 0,0582451 ! protein export from nucleus GO:0006611 40 19 0,000 0,03986321 0,05821029 ! heart process GO:0003015 32 19 0,000 0,03986321 0,05817551 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03986321 0,05814078 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03986321 0,05810609 ! visual learning GO:0008542 38 19 0,000 0,03986321 0,05807144 ! cellular pigmentation GO:0033059 37 19 0,000 0,03986321 0,05803684 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03986321 0,05800227 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03986321 0,05796774 ! vitamin transport GO:0051180 31 19 0,000 0,03986321 0,05793326 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03986321 0,05789882 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03986321 0,05786442 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03986321 0,05783005 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03986321 0,05779573 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03986321 0,05776145 ! cilium assembly GO:0042384 38 19 0,000 0,03986321 0,05772721 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03986321 0,05769302 ! protein secretion GO:0009306 45 20 0,000 0,04191726 0,06062988 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04191726 0,06059401 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04191726 0,06055818 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04191726 0,06052238 ! skin development GO:0043588 42 20 0,000 0,04191726 0,06048664 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04191726 0,06045093 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04191726 0,06041526 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04191726 0,06037964 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,04191726 0,06034406 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04191726 0,06030852 ! response to vitamin GO:0033273 36 20 0,000 0,04191726 0,06027303 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04191726 0,06023757 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04191726 0,06020216 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04191726 0,06016679 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04191726 0,06013146 ! response to alkaloid GO:0043279 38 20 0,000 0,04191726 0,06009617 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04191726 0,06006092 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04191726 0,06002572 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04191726 0,05999055 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04191726 0,05995543 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,04191726 0,05992035 ! body fluid secretion GO:0007589 33 20 0,000 0,04191726 0,05988531 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04191726 0,05985031 ! peptide secretion GO:0002790 38 20 0,000 0,04191726 0,05981535 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04191726 0,05978043 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04191726 0,05974555 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04191726 0,05971071 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04191726 0,05967592 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04191726 0,05964116 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04191726 0,05960645 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04191726 0,05957177 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04191726 0,05953714 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04191726 0,05950254 ! regulation of glucose import GO:0046324 30 20 0,000 0,04191726 0,05946799 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04191726 0,05943347 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04191726 0,059399 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04191726 0,05936456 ! negative regulation of translation GO:0017148 32 20 0,000 0,04191726 0,05933017 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04191726 0,05929582 ! regulation of cell killing GO:0031341 46 21 0,000 0,04396698 0,06215934 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04396698 0,06212339 ! hormone secretion GO:0046879 39 21 0,000 0,04396698 0,06208748 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04396698 0,06205161 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04396698 0,06201579 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04396698 0,06198 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04396698 0,06194426 ! ovarian follicle development GO:0001541 39 21 0,000 0,04396698 0,06190855 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04396698 0,06187289 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04396698 0,06183727 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04396698 0,06180169 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04396698 0,06176615 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04396698 0,06173066 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04396698 0,0616952 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04396698 0,06165978 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04396698 0,06162441 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04396698 0,06158907 ! diencephalon development GO:0021536 36 21 0,000 0,04396698 0,06155378 ! collagen fibril organization GO:0030199 62 21 0,000 0,04396698 0,06151852 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04396698 0,06148331 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04396698 0,06144814 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04396698 0,061413 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04396698 0,06137791 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04396698 0,06134286 ! collagen catabolic process GO:0030574 29 21 0,000 0,04396698 0,06130784 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04396698 0,06127287 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04396698 0,06123794 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04396698 0,06120304 ! actin filament-based movement GO:0030048 47 21 0,000 0,04396698 0,06116819 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04396698 0,06113338 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04601238 0,06394098 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04601238 0,06390463 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04601238 0,06386832 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04601238 0,06383205 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04601238 0,06379582 ! microtubule-based transport GO:0010970 59 22 0,000 0,04601238 0,06375964 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04601238 0,06372349 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04601238 0,06368739 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04601238 0,06365132 ! cellular response to starvation GO:0009267 37 22 0,000 0,04601238 0,0636153 ! vacuolar transport GO:0007034 41 22 0,000 0,04601238 0,06357932 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04601238 0,06354338 ! fucose metabolic process GO:0006004 44 22 0,000 0,04601238 0,06350748 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04601238 0,06347162 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04601238 0,0634358 ! ureteric bud development GO:0001657 50 22 0,000 0,04601238 0,06340002 ! cell aging GO:0007569 48 22 0,000 0,04601238 0,06336428 ! stem cell differentiation GO:0048863 57 22 0,000 0,04601238 0,06332859 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04601238 0,06329293 ! cytolysis GO:0019835 27 22 0,000 0,04601238 0,06325731 ! renal system process GO:0003014 42 22 0,000 0,04601238 0,06322173 ! vasodilation GO:0042311 40 22 0,000 0,04601238 0,06318619 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04601238 0,0631507 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04601238 0,06311524 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04601238 0,06307982 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04601238 0,06304444 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04601238 0,0630091 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04601238 0,0629738 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04601238 0,06293854 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04601238 0,06290332 ! sarcomere organization GO:0045214 32 22 0,000 0,04601238 0,06286814 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04601238 0,062833 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04601238 0,0627979 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04601238 0,06276284 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04601238 0,06272781 ! gut development GO:0048565 44 22 0,000 0,04601238 0,06269283 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04601238 0,06265788 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04601238 0,06262297 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04601238 0,06258811 ! protein stabilization GO:0050821 41 22 0,000 0,04601238 0,06255328 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04805345 0,06529176 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04805345 0,06525547 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04805345 0,06521921 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04805345 0,065183 ! gluconeogenesis GO:0006094 38 23 0,000 0,04805345 0,06514683 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04805345 0,0651107 ! viral genome replication GO:0019079 44 23 0,000 0,04805345 0,0650746 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04805345 0,06503855 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04805345 0,06500254 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04805345 0,06496657 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04805345 0,06493063 ! regeneration GO:0031099 42 23 0,000 0,04805345 0,06489474 ! axis specification GO:0009798 43 23 0,000 0,04805345 0,06485889 ! visual behavior GO:0007632 46 23 0,000 0,04805345 0,06482307 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04805345 0,0647873 ! response to ethanol GO:0045471 47 23 0,000 0,04805345 0,06475156 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04805345 0,06471587 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04805345 0,06468021 ! peroxisome organization GO:0007031 43 23 0,000 0,04805345 0,06464459 ! lysosome organization GO:0007040 47 23 0,000 0,04805345 0,06460902 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04805345 0,06457348 ! vesicle targeting GO:0006903 49 23 0,000 0,04805345 0,06453798 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04805345 0,06450252 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04805345 0,0644671 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04805345 0,06443171 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04805345 0,06439637 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04805345 0,06436107 ! DNA modification GO:0006304 36 23 0,000 0,04805345 0,0643258 ! fatty acid transport GO:0015908 47 23 0,000 0,04805345 0,06429057 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04805345 0,06425538 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04805345 0,06422023 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04805345 0,06418512 ! hormone transport GO:0009914 41 23 0,000 0,04805345 0,06415005 ! cell-cell recognition GO:0009988 28 23 0,000 0,04805345 0,06411501 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04805345 0,06408001 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04805345 0,06404505 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04805345 0,06401013 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,05009022 0,06668687 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,05009022 0,06665055 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,05009022 0,06661426 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,05009022 0,06657802 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,05009022 0,06654182 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,05009022 0,06650565 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,05009022 0,06646953 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,05009022 0,06643344 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,05009022 0,0663974 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,05009022 0,06636139 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,05009022 0,06632542 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,05009022 0,06628949 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,05009022 0,0662536 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,05009022 0,06621775 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,05009022 0,06618194 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,05009022 0,06614616 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,05009022 0,06611043 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,05009022 0,06607473 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,05009022 0,06603907 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,05009022 0,06600345 ! pallium development GO:0021543 56 24 0,000 0,05009022 0,06596787 ! oogenesis GO:0048477 44 24 0,000 0,05009022 0,06593233 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,05009022 0,06589682 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,05009022 0,06586136 ! platelet activation GO:0030168 41 24 0,000 0,05009022 0,06582593 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,05009022 0,06579054 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,05009022 0,06575519 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,05009022 0,06571987 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,05009022 0,0656846 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,05009022 0,06564936 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,05009022 0,06561416 ! regulation of amine transport GO:0051952 41 24 0,000 0,05009022 0,06557899 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,05212268 0,06820338 ! leukocyte adhesion GO:0007159 55 25 0,000 0,05212268 0,06816687 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,05212268 0,0681304 ! phototransduction GO:0007602 37 25 0,000 0,05212268 0,06809396 ! keratinization GO:0031424 37 25 0,000 0,05212268 0,06805757 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,05212268 0,06802121 ! vacuole organization GO:0007033 49 25 0,000 0,05212268 0,0679849 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,05212268 0,06794862 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,05212268 0,06791238 ! receptor metabolic process GO:0043112 53 25 0,000 0,05212268 0,06787618 ! chromosome condensation GO:0030261 48 25 0,000 0,05212268 0,06784002 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,05212268 0,06780389 ! regulation of behavior GO:0050795 48 25 0,000 0,05212268 0,06776781 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,05212268 0,06773176 ! interaction with host GO:0051701 66 25 0,000 0,05212268 0,06769575 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,05212268 0,06765978 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,05212268 0,06762385 ! immunoglobulin production GO:0002377 62 25 0,000 0,05212268 0,06758796 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,05212268 0,0675521 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,05212268 0,06751628 ! liver development GO:0001889 55 25 0,000 0,05212268 0,0674805 ! protein tetramerization GO:0051262 57 25 0,000 0,05212268 0,06744476 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05415086 0,07003205 ! myelination GO:0042552 50 26 0,000 0,05415086 0,06999499 ! initiation of viral infection GO:0019059 60 26 0,000 0,05415086 0,06995798 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05415086 0,069921 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05415086 0,06988407 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05415086 0,06984717 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05415086 0,06981031 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05415086 0,06977349 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05415086 0,06973671 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05415086 0,06969997 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05415086 0,06966326 ! digestive system process GO:0022600 49 26 0,000 0,05415086 0,0696266 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05415086 0,06958997 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,05415086 0,06955339 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05415086 0,06951684 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05415086 0,06948033 ! neural crest cell development GO:0014032 59 26 0,000 0,05415086 0,06944385 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05415086 0,06940742 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05415086 0,06937102 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05415086 0,06933466 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05415086 0,06929834 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05415086 0,06926206 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05415086 0,06922582 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05415086 0,06918961 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05415086 0,06915344 ! blastocyst development GO:0001824 50 26 0,000 0,05415086 0,06911731 ! telomere organization GO:0032200 46 26 0,000 0,05415086 0,06908122 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05415086 0,06904517 ! neural tube closure GO:0001843 58 26 0,000 0,05415086 0,06900915 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05415086 0,06897317 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05415086 0,06893723 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05415086 0,06890132 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05617475 0,0714393 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05617475 0,07140213 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05617475 0,071365 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05617475 0,07132791 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05617475 0,07129086 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05617475 0,07125384 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05617475 0,07121687 ! iron ion transport GO:0006826 65 27 0,000 0,05617475 0,07117993 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05617475 0,07114303 ! tube lumen formation GO:0035148 59 27 0,000 0,05617475 0,07110617 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05617475 0,07106934 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,05617475 0,07103256 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05617475 0,07099581 ! response to starvation GO:0042594 47 27 0,000 0,05617475 0,0709591 ! response to toxin GO:0009636 49 27 0,000 0,05617475 0,07092243 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05617475 0,0708858 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05617475 0,0708492 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05617475 0,07081264 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05617475 0,07077612 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05617475 0,07073964 ! neuron fate commitment GO:0048663 52 28 0,000 0,05819436 0,07324515 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05819436 0,07320743 ! protein amino acid acylation GO:0043543 59 28 0,000 0,05819436 0,07316975 ! circadian rhythm GO:0007623 56 28 0,000 0,05819436 0,07313211 ! dendrite development GO:0016358 67 28 0,000 0,05819436 0,07309451 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05819436 0,07305695 ! fat cell differentiation GO:0045444 57 28 0,000 0,05819436 0,07301943 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05819436 0,07298194 ! sperm motility GO:0030317 37 28 0,000 0,05819436 0,0729445 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05819436 0,07290709 ! base-excision repair GO:0006284 41 28 0,000 0,05819436 0,07286972 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05819436 0,07283239 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05819436 0,0727951 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05819436 0,07275784 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05819436 0,07272063 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05819436 0,07268345 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05819436 0,07264631 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,05819436 0,07260921 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05819436 0,07257214 ! lipid oxidation GO:0034440 48 28 0,000 0,05819436 0,07253512 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05819436 0,07249813 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05819436 0,07246118 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,06020971 0,07493241 ! translational initiation GO:0006413 66 29 0,000 0,06020971 0,07489426 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,06020971 0,07485615 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,06020971 0,07481807 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,06020971 0,07478004 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,06020971 0,07474204 ! autophagy GO:0006914 47 29 0,000 0,06020971 0,07470408 ! primary neural tube formation GO:0014020 61 29 0,000 0,06020971 0,07466616 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,06020971 0,07462828 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,06020971 0,07459043 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,06020971 0,07455263 ! somitogenesis GO:0001756 52 29 0,000 0,06020971 0,07451486 ! synaptogenesis GO:0007416 46 29 0,000 0,06020971 0,07447713 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,06020971 0,07443944 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,06020971 0,07440179 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,06020971 0,07436417 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,06020971 0,07432659 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,06222081 0,07677042 ! phenol metabolic process GO:0018958 56 30 0,000 0,06222081 0,07673167 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,06222081 0,07669296 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,06222081 0,07665428 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,06222081 0,07661564 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,06222081 0,07657705 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,06222081 0,07653849 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,06222081 0,07649997 ! acute-phase response GO:0006953 50 30 0,000 0,06222081 0,07646149 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,06222081 0,07642305 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,06222081 0,07638464 ! myofibril assembly GO:0030239 50 30 0,000 0,06222081 0,07634628 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,06222081 0,07630795 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,06222081 0,07626966 ! cell fate determination GO:0001709 64 30 0,000 0,06222081 0,07623141 ! phospholipid transport GO:0015914 65 30 0,000 0,06222081 0,0761932 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,06222081 0,07615503 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,06222081 0,07611689 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,06222081 0,0760788 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,06222081 0,07604074 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,06222081 0,07600272 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06422766 0,07841488 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06422766 0,07837571 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06422766 0,07833658 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06422766 0,07829749 ! cell junction assembly GO:0034329 85 31 0,000 0,06422766 0,07825844 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06422766 0,07821943 ! ovulation cycle process GO:0022602 55 31 0,000 0,06422766 0,07818045 ! peptide transport GO:0015833 60 31 0,000 0,06422766 0,07814152 ! male gonad development GO:0008584 56 31 0,000 0,06422766 0,07810262 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06422766 0,07806377 ! detection of light stimulus GO:0009583 44 31 0,000 0,06422766 0,07802495 ! natural killer cell activation GO:0030101 50 31 0,000 0,06422766 0,07798617 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06422766 0,07794743 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06422766 0,07790872 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06422766 0,07787006 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06422766 0,07783143 ! eye morphogenesis GO:0048592 65 31 0,000 0,06422766 0,07779284 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06422766 0,0777543 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06623027 0,08013895 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06623027 0,08009928 ! collagen metabolic process GO:0032963 49 32 0,000 0,06623027 0,08005965 ! spindle organization GO:0007051 50 32 0,000 0,06623027 0,08002005 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06623027 0,0799805 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06623027 0,07994098 ! metanephros development GO:0001656 81 32 0,000 0,06623027 0,0799015 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06623027 0,07986207 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,06623027 0,07982267 ! muscle cell development GO:0055001 52 32 0,000 0,06623027 0,07978331 ! mesoderm formation GO:0001707 73 32 0,000 0,06623027 0,07974398 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06623027 0,0797047 ! ovulation cycle GO:0042698 57 32 0,000 0,06623027 0,07966546 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06623027 0,07962625 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06623027 0,07958709 ! hindbrain development GO:0030902 65 32 0,000 0,06623027 0,07954796 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06623027 0,07950887 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06623027 0,07946982 ! gene silencing GO:0016458 71 32 0,000 0,06623027 0,0794308 ! regulation of pH GO:0006885 56 33 0,000 0,06822865 0,08178734 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06822865 0,08174722 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06822865 0,08170715 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06822865 0,08166712 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06822865 0,08162713 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06822865 0,08158717 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06822865 0,08154726 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06822865 0,08150738 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06822865 0,08146754 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06822865 0,08142774 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06822865 0,08138798 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06822865 0,08134826 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06822865 0,08130858 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,07022281 0,08364423 ! post-embryonic development GO:0009791 76 34 0,000 0,07022281 0,08360347 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,07022281 0,08356275 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,07022281 0,08352207 ! spliceosome assembly GO:0000245 75 34 0,000 0,07022281 0,08348142 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,07022281 0,08344082 ! formation of primary germ layer GO:0001704 76 34 0,000 0,07022281 0,08340025 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,07022281 0,08335973 ! adult locomotory behavior GO:0008344 62 34 0,000 0,07022281 0,08331924 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,07022281 0,0832788 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,07221276 0,08559717 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,07221276 0,08555566 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,07221276 0,08551419 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,07221276 0,08547276 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,07221276 0,08543136 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,07221276 0,08539001 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,07221276 0,0853487 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,07221276 0,08530743 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,07221276 0,0852662 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,07221276 0,08522501 ! ceramide metabolic process GO:0006672 72 35 0,000 0,07221276 0,08518386 ! telencephalon development GO:0021537 81 35 0,000 0,07221276 0,08514274 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,07221276 0,08510167 ! vesicle localization GO:0051648 70 35 0,000 0,07221276 0,08506064 ! regulation of muscle development GO:0048634 82 36 0,000 0,0741985 0,08735756 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,0741985 0,08731548 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,0741985 0,08727344 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,0741985 0,08723144 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,0741985 0,08718949 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,0741985 0,08714757 ! positive regulation of cell development GO:0010720 85 36 0,000 0,0741985 0,08710569 ! protein targeting to membrane GO:0006612 75 36 0,000 0,0741985 0,08706385 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,0741985 0,08702206 ! aerobic respiration GO:0009060 56 36 0,000 0,0741985 0,0869803 ! cytokine production GO:0001816 68 36 0,000 0,0741985 0,08693858 ! embryonic organ development GO:0048568 67 36 0,000 0,0741985 0,0868969 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,0741985 0,08685527 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,0741985 0,08681367 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07618005 0,08908945 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07618005 0,08904683 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07618005 0,08900424 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07618005 0,0889617 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07618005 0,08891919 ! odontogenesis GO:0042476 74 37 0,000 0,07618005 0,08887673 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07618005 0,08883431 ! cell junction organization GO:0034330 96 37 0,000 0,07618005 0,08879192 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07618005 0,08874958 ! female gonad development GO:0008585 71 37 0,000 0,07618005 0,08870728 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07618005 0,08866502 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07618005 0,0886228 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,07815742 0,09087985 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07815742 0,09083662 ! meiosis I GO:0007127 74 38 0,000 0,07815742 0,09079343 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07815742 0,09075027 ! organic anion transport GO:0015711 82 38 0,000 0,07815742 0,09070716 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07815742 0,09066409 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07815742 0,09062106 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07815742 0,09057807 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07815742 0,09053512 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07815742 0,09049222 ! regulation of protein stability GO:0031647 77 38 0,000 0,07815742 0,09044935 ! spermatid development GO:0007286 69 38 0,000 0,07815742 0,09040652 ! pigment metabolic process GO:0042440 87 38 0,000 0,07815742 0,09036374 ! neural tube formation GO:0001841 79 38 0,000 0,07815742 0,09032099 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,08013061 0,09255748 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,08013061 0,09251374 ! negative regulation of binding GO:0051100 71 39 0,000 0,08013061 0,09247004 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,08013061 0,09242638 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,08013061 0,09238276 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,08013061 0,09233919 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,08013061 0,09229565 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,08013061 0,09225216 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,08209963 0,09447451 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,08209963 0,09443003 ! learning GO:0007612 82 40 0,000 0,08209963 0,0943856 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,08209963 0,0943412 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,08209963 0,09429685 ! mismatch repair GO:0006298 58 40 0,000 0,08209963 0,09425253 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,08209963 0,09420826 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,08209963 0,09416403 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08406449 0,09637238 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08406449 0,09632718 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08406449 0,09628202 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,08406449 0,0962369 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,08406449 0,09619183 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08406449 0,09614679 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08406449 0,0961018 ! feeding behavior GO:0007631 69 41 0,000 0,08406449 0,09605685 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08406449 0,09601194 ! mesenchymal cell development GO:0014031 94 41 0,000 0,08406449 0,09596708 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,08406449 0,09592226 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08406449 0,09587747 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08406449 0,09583273 ! spermatid differentiation GO:0048515 73 41 0,000 0,08406449 0,09578804 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08406449 0,09574338 ! RNA modification GO:0009451 64 41 0,000 0,08406449 0,09569876 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,0860252 0,09788522 ! ear morphogenesis GO:0042471 64 42 0,000 0,0860252 0,09783965 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,0860252 0,09779412 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,0860252 0,09774863 ! T cell differentiation GO:0030217 93 42 0,000 0,0860252 0,09770319 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,0860252 0,09765779 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,0860252 0,09761243 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,0860252 0,09756711 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,0860252 0,09752184 ! cytokinesis GO:0000910 84 42 0,000 0,0860252 0,09747661 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,0860252 0,09743142 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,08798177 0,09960123 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,08798177 0,0995551 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08798177 0,09950901 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08798177 0,09946296 ! regulation of tube size GO:0035150 76 43 0,000 0,08798177 0,09941696 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,08798177 0,09937099 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08798177 0,09932507 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08798177 0,0992792 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08798177 0,09923336 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08798177 0,09918757 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,08798177 0,09914182 ! segmentation GO:0035282 78 43 0,000 0,08798177 0,09909611 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08798177 0,09905044 ! neuron migration GO:0001764 85 43 0,000 0,08798177 0,09900482 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,0899342 0,10115528 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,0899342 0,10110872 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,0899342 0,10106222 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,0899342 0,10101575 ! striated muscle contraction GO:0006941 85 44 0,000 0,0899342 0,10096933 ! phagocytosis GO:0006909 105 44 0,000 0,0899342 0,10092295 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,0899342 0,10087661 ! double-strand break repair GO:0006302 85 44 0,000 0,0899342 0,10083032 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,09188251 0,10296742 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,09188251 0,10292021 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,09188251 0,10287304 ! biopolymer methylation GO:0043414 91 45 0,000 0,09188251 0,10282592 ! B cell differentiation GO:0030183 124 45 0,000 0,09188251 0,10277884 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,09188251 0,1027318 ! female gamete generation GO:0007292 71 45 0,000 0,09188251 0,1026848 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,09188251 0,10263785 ! polyol metabolic process GO:0019751 77 45 0,000 0,09188251 0,10259094 ! maintenance of location in cell GO:0051651 101 45 0,000 0,09188251 0,10254407 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09382671 0,10466605 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09382671 0,10461828 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,09382671 0,10457055 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,09382671 0,10452287 ! leukocyte migration GO:0050900 75 46 0,000 0,09382671 0,10447522 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09382671 0,10442763 ! pigmentation GO:0043473 103 46 0,000 0,09382671 0,10438007 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,09382671 0,10433256 ! neural tube development GO:0021915 91 47 0,000 0,09576679 0,10644143 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,09576679 0,10639303 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09770278 0,1084945 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09770278 0,1084452 ! mitochondrial transport GO:0006839 94 48 0,000 0,09770278 0,10839595 ! cellular component disassembly GO:0022411 89 48 0,000 0,09770278 0,10834675 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09770278 0,10829759 ! endosome transport GO:0016197 127 48 0,000 0,09770278 0,10824848 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,09770278 0,10819941 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09770278 0,10815038 ! male sex differentiation GO:0046661 93 48 0,000 0,09770278 0,1081014 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09770278 0,10805246 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09770278 0,10800357 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09770278 0,10795472 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09770278 0,10790592 ! methylation GO:0032259 97 48 0,000 0,09770278 0,10785716 ! response to calcium ion GO:0051592 94 49 0,000 0,09963468 0,10994016 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,09963468 0,10989052 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,09963468 0,10984093 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,09963468 0,10979139 ! JNK cascade GO:0007254 106 49 0,000 0,09963468 0,10974189 ! regulation of action potential GO:0001508 102 50 0,000 0,10156249 0,11181485 ! regulation of ion transport GO:0043269 86 50 0,000 0,10156249 0,11176449 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,10156249 0,11171417 ! endocrine system development GO:0035270 109 50 0,000 0,10156249 0,11166389 ! activation of caspase activity GO:0006919 95 50 0,000 0,10156249 0,11161366 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,10156249 0,11156347 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,10156249 0,11151333 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,10156249 0,11146324 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,10156249 0,11141318 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,10156249 0,11136318 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,10348623 0,11342165 ! viral infectious cycle GO:0019058 104 51 0,000 0,10348623 0,11337079 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,10348623 0,11331997 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,10348623 0,1132692 ! positive regulation of binding GO:0051099 88 52 0,000 0,10540591 0,11531869 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,10540591 0,11526707 ! Notch signaling pathway GO:0007219 111 52 0,000 0,10540591 0,11521549 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,10540591 0,11516397 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,10540591 0,11511248 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,10540591 0,11506105 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,10540591 0,11500966 ! excretion GO:0007588 87 52 0,000 0,10540591 0,11495832 ! histone modification GO:0016570 104 52 0,000 0,10540591 0,11490702 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,10540591 0,11485577 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,10540591 0,11480456 ! amino acid activation GO:0043038 98 52 0,000 0,10540591 0,1147534 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10732152 0,11678685 ! inner ear development GO:0048839 89 53 0,000 0,10732152 0,11673486 ! chromatin remodeling GO:0006338 122 53 0,000 0,10732152 0,1166829 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10732152 0,116631 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10732152 0,11657914 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,10732152 0,11652733 ! cartilage development GO:0051216 99 53 0,000 0,10732152 0,11647556 ! synapse organization GO:0050808 102 53 0,000 0,10732152 0,11642384 ! regulation of translational initiation GO:0006446 87 54 0,000 0,1092331 0,11844494 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,1092331 0,11839239 ! neuromuscular process GO:0050905 107 54 0,000 0,1092331 0,11833989 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,1092331 0,11828743 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,1092331 0,11823503 ! covalent chromatin modification GO:0016569 115 54 0,000 0,1092331 0,11818266 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,1092331 0,11813035 ! regulation of cell shape GO:0008360 142 54 0,000 0,1092331 0,11807808 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,1092331 0,11802585 ! RNA catabolic process GO:0006401 103 55 0,000 0,11114063 0,12003384 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,11114063 0,1199808 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,11114063 0,11992781 ! cell recognition GO:0008037 98 55 0,000 0,11114063 0,11987486 ! cell maturation GO:0048469 107 55 0,000 0,11114063 0,11982196 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,11304413 0,12182038 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,11304413 0,12176667 ! regulation of DNA replication GO:0006275 105 56 0,000 0,11304413 0,121713 ! RNA elongation GO:0006354 90 56 0,000 0,11304413 0,12165938 ! chloride transport GO:0006821 102 57 0,000 0,1149436 0,12364915 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,1149436 0,12359473 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,1149436 0,12354035 ! heart morphogenesis GO:0003007 105 57 0,000 0,1149436 0,12348603 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,1149436 0,12343175 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,1149436 0,12337752 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11683907 0,12535698 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11683907 0,12530195 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11683907 0,12524697 ! aging GO:0007568 112 58 0,000 0,11683907 0,12519204 ! gastrulation GO:0007369 122 58 0,000 0,11683907 0,12513715 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11683907 0,12508231 ! maintenance of location GO:0051235 124 58 0,000 0,11683907 0,12502753 ! nuclear export GO:0051168 110 59 0,000 0,11873052 0,12699591 ! establishment of organelle localization GO:0051656 122 59 0,000 0,11873052 0,12694034 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,12061798 0,12890189 ! DNA catabolic process GO:0006308 94 60 0,000 0,12061798 0,12884553 ! regulation of endocytosis GO:0030100 104 60 0,000 0,12061798 0,12878922 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,12061798 0,12873295 ! adult behavior GO:0030534 104 60 0,000 0,12061798 0,12867674 ! kidney development GO:0001822 133 60 0,000 0,12061798 0,12862057 ! positive regulation of secretion GO:0051047 110 61 0,000 0,12250145 0,13057201 ! regulation of cellular component size GO:0032535 125 61 0,000 0,12250145 0,13051507 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,12250145 0,13045817 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,12250145 0,13040133 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,12250145 0,13034453 ! regulation of heart contraction GO:0008016 123 61 0,000 0,12250145 0,13028779 ! camera-type eye development GO:0043010 126 61 0,000 0,12250145 0,13023109 ! proton transport GO:0015992 117 61 0,000 0,12250145 0,13017444 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,12250145 0,13011785 ! viral reproductive process GO:0022415 132 62 0,000 0,12438094 0,13205677 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,12438094 0,13199941 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,12438094 0,13194209 ! tRNA processing GO:0008033 102 62 0,000 0,12438094 0,13188483 ! mesoderm development GO:0007498 128 63 0,000 0,12625646 0,13381541 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,12625646 0,13375738 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12625646 0,1336994 ! hydrogen transport GO:0006818 121 64 0,000 0,12812801 0,1356225 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12812801 0,13556376 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,12812801 0,13550507 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1299956 0,13742071 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,1299956 0,13736127 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,1299956 0,13730188 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,1299956 0,13724255 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1299956 0,13718326 ! ear development GO:0043583 114 66 0,000 0,13185925 0,13908987 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,13185925 0,13902984 ! gonad development GO:0008406 115 66 0,000 0,13185925 0,13896986 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,13371896 0,14086909 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,13371896 0,14080837 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,13371896 0,1407477 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,13371896 0,14068709 ! secondary metabolic process GO:0019748 125 67 0,000 0,13371896 0,14062652 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,13557473 0,14251681 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,13557473 0,14245551 ! extracellular matrix organization GO:0030198 146 68 0,000 0,13557473 0,14239427 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,13557473 0,14233308 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,13557473 0,14227194 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,13557473 0,14221085 ! viral reproduction GO:0016032 142 68 0,000 0,13557473 0,14214982 ! adaptive immune response GO:0002250 126 68 0,000 0,13557473 0,14208883 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,13557473 0,1420279 ! cell projection assembly GO:0030031 138 68 0,000 0,13557473 0,14196703 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13742659 0,14384454 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13742659 0,14378293 ! urogenital system development GO:0001655 149 69 0,000 0,13742659 0,14372138 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13742659 0,14365988 ! single fertilization GO:0007338 83 69 0,000 0,13742659 0,14359844 ! activation of immune response GO:0002253 120 70 0,000 0,13927452 0,14546715 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,13927452 0,14540498 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,14111855 0,14726725 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,14111855 0,14720437 ! appendage morphogenesis GO:0035107 150 72 0,000 0,14295868 0,14906021 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 0,000 0,14295868 0,14899662 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,14295868 0,14893308 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,14295868 0,14886959 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,14295868 0,14880616 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,14295868 0,14874279 ! appendage development GO:0048736 151 73 0,000 0,14479493 0,15058919 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,14479493 0,15052511 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,14479493 0,15046108 ! regulation of immune effector process GO:0002697 156 73 0,000 0,14479493 0,15039711 ! acute inflammatory response GO:0002526 118 74 0,000 0,14662728 0,15223564 ! amino acid transport GO:0006865 148 74 0,000 0,14662728 0,15217097 ! regulation of caspase activity GO:0043281 136 74 0,000 0,14662728 0,15210635 ! organelle localization GO:0051640 155 74 0,000 0,14662728 0,15204179 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,14845577 0,15387248 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,14845577 0,15380723 ! reproductive structure development GO:0048608 131 75 0,000 0,14845577 0,15374203 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,14845577 0,15367688 ! eye development GO:0001654 155 75 0,000 0,14845577 0,15361179 ! axon guidance GO:0007411 162 75 0,000 0,14845577 0,15354676 ! rhythmic process GO:0048511 142 75 0,000 0,14845577 0,15348178 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,15028039 0,15530245 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,15028039 0,15523678 ! learning or memory GO:0007611 161 76 0,000 0,15028039 0,15517117 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,15028039 0,15510561 ! regulation of blood pressure GO:0008217 134 76 0,000 0,15028039 0,15504011 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,15028039 0,15497467 ! amine catabolic process GO:0009310 136 77 0,000 0,15210115 0,15678612 ! neurotransmitter transport GO:0006836 142 77 0,000 0,15210115 0,15671999 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,15210115 0,15665392 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,15210115 0,1565879 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,15210115 0,15652194 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,15210115 0,15645604 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,15391805 0,15825834 ! antigen processing and presentation GO:0019882 117 78 0,000 0,15391805 0,15819176 ! fertilization GO:0009566 99 78 0,000 0,15391805 0,15812523 ! blood coagulation GO:0007596 151 79 0,000 0,15573112 0,15992061 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,15573112 0,15985342 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,15573112 0,15978628 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,15573112 0,1597192 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,15573112 0,15965217 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,15573112 0,1595852 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,15754035 0,16137152 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,15754035 0,16130389 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,15754035 0,16123631 ! meiosis GO:0007126 143 81 0,000 0,15934576 0,16301578 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 0,000 0,16114735 0,16478986 ! meiotic cell cycle GO:0051321 144 82 0,000 0,16114735 0,16472091 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,16294513 0,16648889 ! exocytosis GO:0006887 153 83 0,000 0,16294513 0,16641929 ! response to drug GO:0042493 149 83 0,000 0,16294513 0,16634975 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,16294513 0,16628026 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,16294513 0,16621083 ! inorganic anion transport GO:0015698 156 83 0,000 0,16294513 0,16614146 ! response to metal ion GO:0010038 158 84 0,000 0,1647391 0,16790055 ! T cell activation GO:0042110 189 84 0,000 0,1647391 0,16783054 ! digestion GO:0007586 130 84 0,000 0,1647391 0,16776058 ! regulation of ligase activity GO:0051340 147 84 0,000 0,1647391 0,16769068 ! hemostasis GO:0007599 165 85 0,000 0,16652928 0,16944233 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,16652928 0,16937179 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,16652928 0,16930131 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,16652928 0,16923088 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,16652928 0,16916051 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,16831568 0,17090407 ! regulation of lyase activity GO:0051339 169 86 0,000 0,16831568 0,17083307 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,17009829 0,17257065 ! cellular respiration GO:0045333 143 88 0,000 0,17187714 0,17430297 ! amine biosynthetic process GO:0009309 146 88 0,000 0,17187714 0,17423064 ! sensory perception of smell GO:0007608 117 88 0,000 0,17187714 0,17415838 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,17187714 0,17408617 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,17365222 0,17581118 ! regulation of DNA binding GO:0051101 167 89 0,000 0,17365222 0,17573835 ! cellular defense response GO:0006968 123 89 0,000 0,17365222 0,17566558 ! regulation of neurological system process GO:0031644 175 89 0,000 0,17365222 0,17559287 ! response to inorganic substance GO:0010035 173 90 0,000 0,17542355 0,17731061 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,17542355 0,17723728 ! response to unfolded protein GO:0006986 139 90 0,000 0,17542355 0,17716401 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,17719113 0,17887518 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,18071508 0,18235727 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,18071508 0,18228198 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,18071508 0,18220675 ! vitamin metabolic process GO:0006766 153 93 0,000 0,18071508 0,18213158 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,18247147 0,1838259 ! female pregnancy GO:0007565 166 94 0,000 0,18247147 0,18375012 ! sterol metabolic process GO:0016125 166 94 0,000 0,18247147 0,18367441 ! regulation of defense response GO:0031347 171 95 0,000 0,18422414 0,18536226 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,18422414 0,18528595 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,18422414 0,1852097 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,18422414 0,18513351 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,18422414 0,18505739 ! sex differentiation GO:0007548 171 96 0,000 0,1859731 0,18673748 ! response to protein stimulus GO:0051789 158 96 0,000 0,1859731 0,18666076 ! regulation of T cell activation GO:0050863 175 96 0,000 0,1859731 0,1865841 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,18771836 0,18825778 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,18771836 0,18818053 ! leukocyte differentiation GO:0002521 232 98 0,000 0,18945993 0,18984849 ! forebrain development GO:0030900 210 98 0,000 0,18945993 0,18977065 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,18945993 0,18969288 ! mRNA transport GO:0051028 185 100 0,000 0,19293202 0,1930901 ! positive regulation of immune response GO:0050778 175 100 0,000 0,19293202 0,19301103 ! hormone metabolic process GO:0042445 171 100 0,000 0,19293202 0,19293202