pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/657-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 156 86 6,000 2,916E-09 6,707E-06 ! interphase GO:0051325 159 88 6,000 3,432E-09 3,946E-06 ! regulation of epithelial cell proliferation GO:0050678 71 39 4,000 6,066E-08 4,651E-05 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 1,006E-07 5,785E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 3,000 2,152E-07 9,901E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 4,000 2,416E-07 9,262E-05 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 2,000 6,326E-07 2,079E-04 ! regulation of granule cell precursor proliferation GO:0021936 11 7 2,000 6,326E-07 1,819E-04 GO:0021940|positive regulation of granule cell precursor proliferation, ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 1,01E-06 2,582E-04 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 2,000 2,96E-06 6,808E-04 ! regulation of monooxygenase activity GO:0032768 26 13 2,000 5,111E-06 1,069E-03 ! positive regulation of cell cycle GO:0045787 77 45 3,000 6,301E-06 1,208E-03 ! activation of MAPKK activity GO:0000186 21 14 2,000 6,493E-06 1,149E-03 ! response to UV GO:0009411 75 46 3,000 6,888E-06 1,132E-03 ! G1 phase GO:0051318 27 16 2,000 9,952E-06 1,526E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 1,206E-05 1,734E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,632E-05 2,207E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 1,712E-05 2,188E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 1,712E-05 2,073E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 1,712E-05 1,969E-03 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,749E-05 1,916E-03 ! homeostasis of number of cells GO:0048872 84 61 3,000 2,139E-05 2,236E-03 ! negative regulation of transferase activity GO:0051348 105 61 3,000 2,139E-05 2,139E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 2,341E-05 2,244E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 2,341E-05 2,154E-03 ! negative regulation of cell size GO:0045792 108 64 3,000 2,589E-05 2,29E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 2,706E-05 2,305E-03 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 3,106E-05 2,551E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 3,543E-05 2,81E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 2,000 3,543E-05 2,716E-03 ! regulation of oxidoreductase activity GO:0051341 39 24 2,000 3,543E-05 2,629E-03 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 3,692E-05 2,653E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 4,018E-05 2,801E-03 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 4,126E-05 2,791E-03 GO:0045937|positive regulation of phosphate metabolic process, ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 4,534E-05 2,979E-03 ! erythrocyte differentiation GO:0030218 38 28 2,000 5,691E-05 3,636E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 1,000 7,038E-05 4,375E-03 ! anagen GO:0042640 6 5 1,000 7,038E-05 4,26E-03 ! response to food GO:0032094 5 5 1,000 7,038E-05 4,151E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 1,000 7,038E-05 4,047E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 7,038E-05 3,948E-03 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 7,038E-05 3,854E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 7,038E-05 3,765E-03 ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 7,038E-05 3,679E-03 ! cellular anion homeostasis GO:0030002 6 5 1,000 7,038E-05 3,597E-03 GO:0055081|anion homeostasis, ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 7,916E-05 3,958E-03 ! cell cycle arrest GO:0007050 150 86 3,000 8,285E-05 4,055E-03 ! erythrocyte homeostasis GO:0034101 45 34 2,000 1,028E-04 4,925E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,028E-04 4,825E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 1,054E-04 4,848E-03 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 1,054E-04 4,753E-03 ! gas homeostasis GO:0033483 11 6 1,000 1,054E-04 4,662E-03 ! hair follicle maturation GO:0048820 7 6 1,000 1,054E-04 4,574E-03 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 1,000 1,054E-04 4,489E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 1,054E-04 4,407E-03 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 1,054E-04 4,329E-03 ! response to light stimulus GO:0009416 153 96 3,000 1,271E-04 5,128E-03 ! gliogenesis GO:0042063 71 38 2,000 1,438E-04 5,703E-03 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,473E-04 5,742E-03 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 1,473E-04 5,646E-03 ! vesicle fusion GO:0006906 15 7 1,000 1,473E-04 5,554E-03 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 1,473E-04 5,464E-03 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 1,000 1,473E-04 5,377E-03 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 1,678E-04 6,03E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,961E-04 6,937E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,961E-04 6,832E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 1,961E-04 6,73E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,961E-04 6,631E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,961E-04 6,535E-03 ! induction of an organ GO:0001759 11 8 1,000 1,961E-04 6,442E-03 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,961E-04 6,351E-03 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 1,000 1,961E-04 6,263E-03 ! response to insulin stimulus GO:0032868 63 43 2,000 2,084E-04 6,567E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 2,387E-04 7,421E-03 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 1,000 2,516E-04 7,717E-03 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 2,516E-04 7,615E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 1,000 2,516E-04 7,517E-03 GO:0010469|regulation of receptor activity, ! erythrocyte development GO:0048821 11 9 1,000 2,516E-04 7,42E-03 ! positive regulation of protein polymerization GO:0032273 15 9 1,000 2,516E-04 7,326E-03 ! localization within membrane GO:0051668 15 9 1,000 2,516E-04 7,235E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 3,14E-04 8,916E-03 ! glucan biosynthetic process GO:0009250 13 10 1,000 3,14E-04 8,808E-03 GO:0005978|glycogen biosynthetic process, ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 3,14E-04 8,702E-03 ! developmental induction GO:0031128 13 10 1,000 3,14E-04 8,598E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of cell migration GO:0030335 92 51 2,000 3,464E-04 9,374E-03 ! positive regulation of organelle organization GO:0010638 82 51 2,000 3,464E-04 9,265E-03 ! T cell homeostasis GO:0043029 20 11 1,000 3,831E-04 0,01012885 ! actin filament polymerization GO:0030041 17 11 1,000 3,831E-04 0,01001375 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 4,568E-04 0,01180579 ! positive regulation of cell motion GO:0051272 99 56 2,000 4,568E-04 0,01167461 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 4,59E-04 0,01160044 ! negative regulation of endothelial cell migration GO:0010596 21 12 1,000 4,59E-04 0,01147435 ! gland morphogenesis GO:0022612 23 12 1,000 4,59E-04 0,01135097 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 4,59E-04 0,01123021 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 4,813E-04 0,01165267 ! activation of MAPK activity GO:0000187 84 59 2,000 5,327E-04 0,0127636 ! myeloid cell differentiation GO:0030099 85 59 2,000 5,327E-04 0,01263201 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 5,415E-04 0,01270854 ! lipid localization GO:0010876 24 13 1,000 5,415E-04 0,01258017 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 5,415E-04 0,01245437 ! regulation of transmembrane transporter activity GO:0022898 19 13 1,000 5,415E-04 0,01233106 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 5,415E-04 0,01221017 ! lymphocyte homeostasis GO:0002260 24 13 1,000 5,415E-04 0,01209162 ! negative regulation of cell growth GO:0030308 106 62 2,000 6,163E-04 0,01362945 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 6,307E-04 0,01381449 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 6,307E-04 0,01368416 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 6,307E-04 0,01355627 ! G1/S transition checkpoint GO:0031575 33 14 1,000 6,307E-04 0,01343075 ! DNA unwinding during replication GO:0006268 21 14 1,000 6,307E-04 0,01330753 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 6,307E-04 0,01318656 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 6,459E-04 0,01338324 ! cell cycle checkpoint GO:0000075 108 64 2,000 6,764E-04 0,01388992 ! lipid phosphorylation GO:0046834 23 15 1,000 7,264E-04 0,01478594 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 1,000 7,264E-04 0,01465624 ! positive regulation of proteolysis GO:0045862 19 15 1,000 7,264E-04 0,0145288 ! regulation of survival gene product expression GO:0045884 20 15 1,000 7,264E-04 0,01440355 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 7,264E-04 0,01428044 ! regulation of vasodilation GO:0042312 24 15 1,000 7,264E-04 0,01415942 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 7,264E-04 0,01404043 ! DNA replication initiation GO:0006270 25 16 1,000 8,288E-04 0,01588524 ! activation of protein kinase activity GO:0032147 102 69 2,000 8,426E-04 0,01601662 ! inactivation of MAPK activity GO:0000188 27 17 1,000 9,377E-04 0,01767782 ! DNA duplex unwinding GO:0032508 25 17 1,000 9,377E-04 0,0175341 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 31 17 1,000 9,377E-04 0,0173927 ! peptidyl-serine modification GO:0018209 27 17 1,000 9,377E-04 0,01725356 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 1,033E-03 0,01885209 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 1,053E-03 0,01907187 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 1,053E-03 0,01892287 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 1,053E-03 0,01877619 ! cellular response to nutrient levels GO:0031669 27 18 1,000 1,053E-03 0,01863175 ! negative regulation of growth GO:0045926 123 75 2,000 1,074E-03 0,01885262 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 1,175E-03 0,02047311 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 1,175E-03 0,02031918 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 1,175E-03 0,02016754 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 1,175E-03 0,02001816 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 1,175E-03 0,01987096 ! chromatin assembly GO:0031497 102 80 2,000 1,294E-03 0,02172901 GO:0006334|nucleosome assembly, ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 1,303E-03 0,02172163 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 1,303E-03 0,02156536 ! positive regulation of B cell activation GO:0050871 31 20 1,000 1,303E-03 0,02141132 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 1,000 1,438E-03 0,02345711 ! vesicle docking GO:0048278 27 21 1,000 1,438E-03 0,02329191 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 1,438E-03 0,02312903 ! regulation of vasoconstriction GO:0019229 31 21 1,000 1,438E-03 0,02296842 ! protein-DNA complex assembly GO:0065004 107 84 2,000 1,49E-03 0,02363147 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 1,579E-03 0,02487653 ! regulation of transmembrane transport GO:0034762 30 22 1,000 1,579E-03 0,0247073 ! molting cycle process GO:0022404 40 22 1,000 1,579E-03 0,02454036 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! vasculogenesis GO:0001570 33 22 1,000 1,579E-03 0,02437566 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 1,579E-03 0,02421316 GO:0010810|regulation of cell-substrate adhesion, ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 1,579E-03 0,02405281 ! membrane depolarization GO:0051899 35 22 1,000 1,579E-03 0,02389456 ! leukocyte homeostasis GO:0001776 33 22 1,000 1,579E-03 0,02373839 ! regulation of blood coagulation GO:0030193 34 22 1,000 1,579E-03 0,02358424 ! nucleosome organization GO:0034728 114 87 2,000 1,648E-03 0,02445384 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 1,727E-03 0,02545559 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 1,88E-03 0,02754568 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 1,88E-03 0,02737134 ! glutathione metabolic process GO:0006749 29 24 1,000 1,88E-03 0,02719919 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 1,88E-03 0,02702919 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 1,000 2,04E-03 0,02914716 ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 2,04E-03 0,02896724 ! positive regulation of nuclear division GO:0051785 39 25 1,000 2,04E-03 0,02878953 GO:0045840|positive regulation of mitosis, ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 2,207E-03 0,03094549 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 2,207E-03 0,03075794 ! regulation of coagulation GO:0050818 39 26 1,000 2,207E-03 0,03057265 ! membrane docking GO:0022406 39 27 1,000 2,379E-03 0,03276465 ! respiratory gaseous exchange GO:0007585 47 27 1,000 2,379E-03 0,03256963 ! cholesterol homeostasis GO:0042632 46 28 1,000 2,558E-03 0,03480786 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 1,000 2,558E-03 0,0346031 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 2,558E-03 0,03440075 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 2,558E-03 0,03420074 ! positive regulation of catabolic process GO:0009896 40 28 1,000 2,558E-03 0,03400305 ! placenta development GO:0001890 37 28 1,000 2,558E-03 0,03380763 ! regulation of B cell activation GO:0050864 42 28 1,000 2,558E-03 0,03361444 ! cholesterol transport GO:0030301 46 30 1,000 2,933E-03 0,03833219 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 1,000 2,933E-03 0,03811562 ! response to heat GO:0009408 41 30 1,000 2,933E-03 0,03790149 ! negative regulation of secretion GO:0051048 49 31 1,000 3,13E-03 0,04022024 ! mammary gland development GO:0030879 57 31 1,000 3,13E-03 0,03999679 ! glial cell differentiation GO:0010001 55 31 1,000 3,13E-03 0,03977581 ! cell fate specification GO:0001708 37 31 1,000 3,13E-03 0,03955726 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 3,333E-03 0,04189219 ! neutral lipid metabolic process GO:0006638 41 32 1,000 3,333E-03 0,04166451 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 1,000 3,333E-03 0,0414393 ! lipid homeostasis GO:0055088 55 33 1,000 3,542E-03 0,04380073 ! regulation of proteolysis GO:0030162 50 33 1,000 3,542E-03 0,0435665 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 3,542E-03 0,04333476 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 3,757E-03 0,04572139 ! glycerol ether metabolic process GO:0006662 44 34 1,000 3,757E-03 0,04548075 ! polysaccharide biosynthetic process GO:0000271 47 35 1,000 3,978E-03 0,04790271 ! glycogen metabolic process GO:0005977 48 35 1,000 3,978E-03 0,04765322 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 3,978E-03 0,04740631 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 3,978E-03 0,04716195 ! organic ether metabolic process GO:0018904 46 36 1,000 4,205E-03 0,04959533 ! tissue remodeling GO:0048771 62 36 1,000 4,205E-03 0,04934229 ! glucan metabolic process GO:0044042 49 36 1,000 4,205E-03 0,04909182 GO:0006073|cellular glucan metabolic process, ! regulation of protein secretion GO:0050708 51 37 1,000 4,438E-03 0,05154687 ! striated muscle cell differentiation GO:0051146 54 38 1,000 4,676E-03 0,05404481 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 4,92E-03 0,05658465 ! developmental growth GO:0048589 62 39 1,000 4,92E-03 0,05630314 ! cell growth GO:0016049 61 39 1,000 4,92E-03 0,05602441 ! peptide metabolic process GO:0006518 56 40 1,000 5,171E-03 0,05858249 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 5,171E-03 0,05829532 ! energy reserve metabolic process GO:0006112 59 41 1,000 5,426E-03 0,0608819 ! glucose transport GO:0015758 52 41 1,000 5,426E-03 0,06058636 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 5,688E-03 0,06320044 ! hexose transport GO:0008645 54 42 1,000 5,688E-03 0,06289659 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 1,000 5,688E-03 0,06259565 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 5,955E-03 0,06522513 ! vesicle organization GO:0016050 79 43 1,000 5,955E-03 0,064916 ! glycolysis GO:0006096 53 44 1,000 6,228E-03 0,06757112 ! negative regulation of cell migration GO:0030336 92 44 1,000 6,228E-03 0,06725388 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 6,228E-03 0,06693961 ! cell redox homeostasis GO:0045454 63 46 1,000 6,791E-03 0,07264852 ! regulation of ossification GO:0030278 71 46 1,000 6,791E-03 0,07231219 ! negative regulation of immune system process GO:0002683 73 47 1,000 7,081E-03 0,07504998 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 7,081E-03 0,07470572 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 1,000 7,081E-03 0,07436459 ! regulation of muscle contraction GO:0006937 69 48 1,000 7,376E-03 0,07711359 ! response to temperature stimulus GO:0009266 62 48 1,000 7,376E-03 0,07676466 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 7,376E-03 0,07641887 ! regulation of angiogenesis GO:0045765 94 49 1,000 7,677E-03 0,07917844 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 7,677E-03 0,07882497 ! germ cell development GO:0007281 68 49 1,000 7,677E-03 0,07847464 ! membrane fusion GO:0006944 80 50 1,000 7,983E-03 0,08124418 ! lipid modification GO:0030258 73 50 1,000 7,983E-03 0,08088628 ! positive regulation of growth GO:0045927 67 50 1,000 7,983E-03 0,08053152 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 7,983E-03 0,08017985 ! activation of phospholipase C activity GO:0007202 87 51 1,000 8,295E-03 0,08294825 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein catabolic process GO:0042176 77 51 1,000 8,295E-03 0,08258917 ! negative regulation of cell motion GO:0051271 104 51 1,000 8,295E-03 0,08223318 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 8,612E-03 0,08501056 ! regulation of bone remodeling GO:0046850 90 53 1,000 8,934E-03 0,08781712 ! regulation of protein complex assembly GO:0043254 81 54 1,000 9,262E-03 0,09065218 ! regulation of mitosis GO:0007088 84 54 1,000 9,262E-03 0,09026806 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 1,000 9,262E-03 0,08988718 ! regulation of phospholipase activity GO:0010517 90 54 1,000 9,262E-03 0,08950951 ! regulation of tissue remodeling GO:0034103 91 54 1,000 9,262E-03 0,08913499 ! positive regulation of lipase activity GO:0060193 90 54 1,000 9,262E-03 0,08876359 ! carbohydrate transport GO:0008643 74 57 1,000 0,01027766 0,09808557 ! developmental maturation GO:0021700 75 57 1,000 0,01027766 0,09768026 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,01062663 0,10058125 ! lung development GO:0030324 94 59 1,000 0,0109808 0,10350754 ! actin filament organization GO:0007015 95 59 1,000 0,0109808 0,10308506 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,01134015 0,10602576 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01134015 0,10559651 ! respiratory tube development GO:0030323 99 62 1,000 0,01207425 0,11197896 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,01244895 0,11499033 ! regulation of lipase activity GO:0060191 109 63 1,000 0,01244895 0,11453037 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,01282871 0,11755395 ! hexose catabolic process GO:0019320 82 64 1,000 0,01282871 0,11708747 ! respiratory system development GO:0060541 100 64 1,000 0,01282871 0,11662467 ! defense response to bacterium GO:0042742 73 65 1,000 0,01321351 0,11964985 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,01321351 0,11918064 ! protein oligomerization GO:0051259 100 65 1,000 0,01321351 0,11871509 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01337183 0,11967011 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01337183 0,11920628 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01337183 0,11874602 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01337183 0,1182893 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01337183 0,11783609 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01337183 0,11738633 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01337183 0,11694 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01337183 0,11649704 ! sleep GO:0030431 11 5 0,000 0,01337183 0,11605743 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01337183 0,11562112 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01337183 0,11518809 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01337183 0,11475828 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01337183 0,11433167 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01337183 0,11390822 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01337183 0,11348789 ! tongue development GO:0043586 6 5 0,000 0,01337183 0,11307066 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01337183 0,11265648 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01337183 0,11224533 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01337183 0,11183716 ! cobalt ion transport GO:0006824 9 5 0,000 0,01337183 0,11143195 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01337183 0,11102967 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01337183 0,11063028 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01337183 0,11023376 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01337183 0,10984007 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01337183 0,10944918 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01337183 0,10906106 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01337183 0,10867569 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01337183 0,10829302 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01337183 0,10791305 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01337183 0,10753573 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01337183 0,10716104 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01337183 0,10678896 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01337183 0,10641944 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01337183 0,10605248 ! malate metabolic process GO:0006108 7 5 0,000 0,01337183 0,10568804 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01337183 0,10532609 ! behavioral response to pain GO:0048266 7 5 0,000 0,01337183 0,10496662 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01337183 0,10460959 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01337183 0,10425498 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01337183 0,10390277 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01337183 0,10355293 ! mating behavior GO:0007617 6 5 0,000 0,01337183 0,10320543 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01337183 0,10286026 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01337183 0,1025174 ! rhythmic behavior GO:0007622 12 5 0,000 0,01337183 0,10217681 ! copulation GO:0007620 7 5 0,000 0,01337183 0,10183847 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01337183 0,10150237 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01337183 0,10116848 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01337183 0,10083678 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01337183 0,10050725 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01337183 0,10017987 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01337183 0,09985461 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01337183 0,09953145 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01337183 0,09921038 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01337183 0,09889138 ! response to protozoan GO:0001562 9 5 0,000 0,01337183 0,09857442 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01337183 0,09825949 ! lymph vessel development GO:0001945 7 5 0,000 0,01337183 0,09794656 ! endochondral ossification GO:0001958 12 5 0,000 0,01337183 0,09763562 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01337183 0,09732664 ! parathyroid gland development GO:0060017 8 5 0,000 0,01337183 0,09701962 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01337183 0,09671453 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01337183 0,09641135 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01337183 0,09611006 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01337183 0,09581065 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01337183 0,0955131 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01337183 0,0952174 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01337183 0,09492352 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01337183 0,09463144 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01337183 0,09434116 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01337183 0,09405266 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01337183 0,09376591 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01337183 0,09348091 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01337183 0,09319763 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01337183 0,09291607 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01337183 0,0926362 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01337183 0,09235802 ! ovulation GO:0030728 6 5 0,000 0,01337183 0,09208149 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01337183 0,09180662 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01337183 0,09153339 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01337183 0,09126178 ! response to pH GO:0009268 9 5 0,000 0,01337183 0,09099177 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01337183 0,09072336 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01337183 0,09045653 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01337183 0,09019126 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01337183 0,08992754 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01337183 0,08966536 ! polyol catabolic process GO:0046174 7 5 0,000 0,01337183 0,08940471 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01337183 0,08914556 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01337183 0,08888792 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01337183 0,08863176 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01337183 0,08837707 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01337183 0,08812384 ! urea metabolic process GO:0019627 6 5 0,000 0,01337183 0,08787205 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01337183 0,08762171 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01337183 0,08737278 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01337183 0,08712527 ! neutrophil activation GO:0042119 5 5 0,000 0,01337183 0,08687915 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01337183 0,08663442 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01337183 0,08639106 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01337183 0,08614907 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01337183 0,08590843 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01337183 0,08566913 ! forebrain neuron development GO:0021884 7 5 0,000 0,01337183 0,08543116 ! melanosome organization GO:0032438 7 5 0,000 0,01337183 0,08519451 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01337183 0,08495917 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01337183 0,08472512 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01337183 0,08449236 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01337183 0,08426087 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01337183 0,08403065 ! nucleoside transport GO:0015858 6 5 0,000 0,01337183 0,08380169 ! nucleoside salvage GO:0043174 7 5 0,000 0,01337183 0,08357396 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01337183 0,08334748 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01337183 0,08312221 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01337183 0,08289816 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01337183 0,08267532 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01337183 0,08245367 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01337183 0,08223321 ! depyrimidination GO:0045008 8 5 0,000 0,01337183 0,08201392 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01337183 0,0817958 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01337183 0,08157883 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01337183 0,08136301 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01337183 0,08114834 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01337183 0,08093479 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01337183 0,08072236 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01337183 0,08051104 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01337183 0,08030083 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01337183 0,08009172 ! monocyte differentiation GO:0030224 8 5 0,000 0,01337183 0,07988369 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01337183 0,07967673 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01337183 0,07947085 ! centrosome duplication GO:0051298 5 5 0,000 0,01337183 0,07926603 ! response to UV-C GO:0010225 6 5 0,000 0,01337183 0,07906226 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01337183 0,07885954 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01337183 0,07865785 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01337183 0,07845719 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01337183 0,07825755 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01337183 0,07805893 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01337183 0,07786131 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01337183 0,07766469 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01337183 0,07746907 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01337183 0,07727442 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01337183 0,07708075 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01337183 0,07688805 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01337183 0,07669631 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01337183 0,07650552 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01337183 0,07631568 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01337183 0,07612678 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01337183 0,07593881 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01337183 0,07575177 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01337183 0,07556565 ! neural tube patterning GO:0021532 6 5 0,000 0,01337183 0,07538044 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01337183 0,07519613 ! histone demethylation GO:0016577 9 5 0,000 0,01337183 0,07501273 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01337183 0,07483022 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01337183 0,07464859 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01337183 0,07446784 ! enteric nervous system development GO:0048484 8 5 0,000 0,01337183 0,07428797 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01337183 0,07410896 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01337183 0,07393082 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01337183 0,07375352 ! transcription termination GO:0006353 8 5 0,000 0,01337183 0,07357708 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01337183 0,07340148 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01337183 0,07322671 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01337183 0,07305278 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01337183 0,07287967 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01337183 0,07270737 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01337183 0,07253589 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01337183 0,07236522 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01337183 0,07219535 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01337183 0,07202627 ! apical protein localization GO:0045176 6 5 0,000 0,01337183 0,07185799 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01337183 0,07169049 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01337183 0,07152377 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01337183 0,07135782 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01337183 0,07119264 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01337183 0,07102822 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01337183 0,07086456 ! glial cell migration GO:0008347 10 5 0,000 0,01337183 0,07070165 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01337183 0,07053949 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01337183 0,07037808 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01337183 0,0702174 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01337183 0,07005745 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01337183 0,06989823 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01337183 0,06973973 ! neural plate development GO:0001840 6 5 0,000 0,01337183 0,06958194 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01337183 0,06942487 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01337183 0,06926851 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01337183 0,06911285 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01337183 0,06895789 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01337183 0,06880362 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01337183 0,06865004 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01337183 0,06849715 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01337183 0,06834493 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01337183 0,06819339 ! spindle assembly GO:0051225 5 5 0,000 0,01337183 0,06804252 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01337183 0,06789232 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01337183 0,06774277 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01337183 0,06759389 ! organ regeneration GO:0031100 7 5 0,000 0,01337183 0,06744566 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01337183 0,06729807 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01337183 0,06715113 GO:0006577|betaine metabolic process, ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,01439778 0,07214575 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,01521194 0,07605968 ! regulation of catabolic process GO:0009894 106 70 1,000 0,01521194 0,07589469 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,01562632 0,07779336 ! monosaccharide catabolic process GO:0046365 91 71 1,000 0,01562632 0,07762534 ! muscle cell differentiation GO:0042692 104 71 1,000 0,01562632 0,07745804 ! tRNA transcription GO:0009304 11 6 0,000 0,01602512 0,07926405 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01602512 0,07909395 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01602512 0,07892459 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01602512 0,07875595 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01602512 0,07858802 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01602512 0,07842081 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01602512 0,07825432 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01602512 0,07808852 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01602512 0,07792343 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01602512 0,07775904 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01602512 0,07759533 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01602512 0,07743232 ! prostate gland development GO:0030850 9 6 0,000 0,01602512 0,07726998 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01602512 0,07710833 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01602512 0,07694735 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01602512 0,07678705 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01602512 0,07662741 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01602512 0,07646843 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01602512 0,07631011 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01602512 0,07615244 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01602512 0,07599543 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01602512 0,07583906 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01602512 0,07568333 ! neuron adhesion GO:0007158 9 6 0,000 0,01602512 0,07552824 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01602512 0,07537379 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01602512 0,07521996 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01602512 0,07506677 ! signal peptide processing GO:0006465 8 6 0,000 0,01602512 0,07491419 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01602512 0,07476224 ! mRNA stabilization GO:0048255 15 6 0,000 0,01602512 0,0746109 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01602512 0,07446017 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01602512 0,07431005 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01602512 0,07416053 ! opsonization GO:0008228 8 6 0,000 0,01602512 0,07401161 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01602512 0,07386329 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01602512 0,07371557 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01602512 0,07356843 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01602512 0,07342188 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01602512 0,07327591 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01602512 0,07313052 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01602512 0,07298571 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01602512 0,07284147 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01602512 0,0726978 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01602512 0,07255469 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01602512 0,07241215 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01602512 0,07227016 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01602512 0,07212873 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01602512 0,07198786 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01602512 0,07184753 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01602512 0,07170775 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01602512 0,07156851 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01602512 0,07142981 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01602512 0,07129165 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01602512 0,07115402 ! thymic T cell selection GO:0045061 12 6 0,000 0,01602512 0,07101692 ! protein lipoylation GO:0009249 10 6 0,000 0,01602512 0,07088035 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01602512 0,0707443 ! pigment granule organization GO:0048753 11 6 0,000 0,01602512 0,07060878 ! drug transport GO:0015893 6 6 0,000 0,01602512 0,07047377 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01602512 0,07033928 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01602512 0,0702053 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01602512 0,07007183 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01602512 0,06993887 ! histidine metabolic process GO:0006547 6 6 0,000 0,01602512 0,06980641 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01602512 0,06967445 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01602512 0,06954299 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01602512 0,06941202 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01602512 0,06928155 ! adenohypophysis development GO:0021984 10 6 0,000 0,01602512 0,06915156 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01602512 0,06902206 ! hyperosmotic response GO:0006972 8 6 0,000 0,01602512 0,06889305 ! microtubule nucleation GO:0007020 10 6 0,000 0,01602512 0,06876452 ! ER overload response GO:0006983 7 6 0,000 0,01602512 0,06863647 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01602512 0,06850889 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01602512 0,06838179 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01602512 0,06825515 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01602512 0,06812899 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01602512 0,06800329 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01602512 0,06787805 ! response to dietary excess GO:0002021 7 6 0,000 0,01602512 0,06775328 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01602512 0,06762896 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01602512 0,0675051 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01602512 0,06738169 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01602512 0,06725873 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01602512 0,06713622 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01602512 0,06701415 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01602512 0,06689253 ! neuron apoptosis GO:0051402 8 6 0,000 0,01602512 0,06677135 ! organic alcohol transport GO:0015850 9 6 0,000 0,01602512 0,0666506 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01602512 0,06653029 ! male sex determination GO:0030238 9 6 0,000 0,01602512 0,06641042 ! carnitine transport GO:0015879 8 6 0,000 0,01602512 0,06629098 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01602512 0,06617196 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01602512 0,06605337 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01602512 0,06593521 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01602512 0,06581747 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01602512 0,06570015 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01602512 0,06558324 ! parturition GO:0007567 12 6 0,000 0,01602512 0,06546675 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01602512 0,06535068 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01602512 0,06523501 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01602512 0,06511976 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01602512 0,06500491 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01602512 0,06489046 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01602512 0,06477642 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01602512 0,06466278 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01602512 0,06454953 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01602512 0,06443668 ! macrophage differentiation GO:0030225 10 6 0,000 0,01602512 0,06432423 ! astrocyte development GO:0014002 14 6 0,000 0,01602512 0,06421216 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01602512 0,06410049 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01602512 0,06398921 ! interaction with symbiont GO:0051702 8 6 0,000 0,01602512 0,06387831 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01602512 0,06376779 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01602512 0,06365766 ! eating behavior GO:0042755 6 6 0,000 0,01602512 0,0635479 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01602512 0,06343852 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01602512 0,06332952 ! response to copper ion GO:0046688 9 6 0,000 0,01602512 0,0632209 ! DNA topological change GO:0006265 8 6 0,000 0,01602512 0,06311264 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01602512 0,06300476 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01602512 0,06289724 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01602512 0,06279009 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01602512 0,0626833 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01602512 0,06257688 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01602512 0,06247082 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01602512 0,06236511 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01602512 0,06225977 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01602512 0,06215478 ! Schwann cell development GO:0014044 14 6 0,000 0,01602512 0,06205014 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01602512 0,06194585 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01602512 0,06184192 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01602512 0,06173833 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01602512 0,06163509 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01602512 0,06153219 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01602512 0,06142964 ! histone ubiquitination GO:0016574 7 6 0,000 0,01602512 0,06132743 ! regulation of meiosis GO:0040020 10 6 0,000 0,01602512 0,06122555 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01602512 0,06112402 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01602512 0,06102282 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01602512 0,06092195 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01602512 0,06082142 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01602512 0,06072122 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01602512 0,06062135 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01602512 0,06052181 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01602512 0,06042259 ! receptor internalization GO:0031623 9 6 0,000 0,01602512 0,0603237 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01602512 0,06022514 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01602512 0,06012689 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01602512 0,06002896 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01602512 0,05993135 ! protein deubiquitination GO:0016579 8 6 0,000 0,01602512 0,05983406 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01602512 0,05973709 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01602512 0,05964043 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01602512 0,05954408 ! axonal fasciculation GO:0007413 9 6 0,000 0,01602512 0,05944804 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01602512 0,05935231 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01602512 0,05925689 ! midbrain development GO:0030901 6 6 0,000 0,01602512 0,05916177 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01602512 0,05906696 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01602512 0,05897245 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01602512 0,05887825 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01602512 0,05878434 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01602512 0,05869074 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01602512 0,05859743 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01602512 0,05850442 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01602512 0,0584117 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01602512 0,05831928 ! adult feeding behavior GO:0008343 6 6 0,000 0,01602512 0,05822714 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01602512 0,0581353 ! blastocyst growth GO:0001832 15 6 0,000 0,01602512 0,05804375 ! pigment granule transport GO:0051904 12 6 0,000 0,01602512 0,05795249 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01602512 0,05786151 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01602512 0,05777082 ! catecholamine transport GO:0051937 7 6 0,000 0,01602512 0,05768041 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01602512 0,05759029 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01602512 0,05750044 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01602512 0,05741088 ! protein prenylation GO:0018342 10 6 0,000 0,01602512 0,05732159 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01602512 0,05723258 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01602512 0,05714385 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01602512 0,05705539 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,01604553 0,05703977 ! response to hypoxia GO:0001666 132 72 1,000 0,01604553 0,05695174 ! negative regulation of transport GO:0051051 116 73 1,000 0,01646956 0,05836669 ! tube morphogenesis GO:0035239 118 73 1,000 0,01646956 0,05827689 ! mitochondrion organization GO:0007005 104 73 1,000 0,01646956 0,05818737 ! response to oxygen levels GO:0070482 137 74 1,000 0,01689836 0,05961077 ! protein import into nucleus GO:0006606 118 74 1,000 0,01689836 0,05951948 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,01689836 0,05942847 ! response to nutrient GO:0007584 104 75 1,000 0,01733191 0,06086013 ! nuclear import GO:0051170 121 75 1,000 0,01733191 0,06076735 ! regulation of protein transport GO:0051223 114 76 1,000 0,01777018 0,06220915 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 1,000 0,01821315 0,06366298 ! protein ubiquitination GO:0016567 125 77 1,000 0,01821315 0,06356637 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,01821315 0,06347006 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,01866078 0,06493162 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01867143 0,06487052 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01867143 0,06477267 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01867143 0,06467513 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01867143 0,06457787 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01867143 0,06448091 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01867143 0,06438423 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01867143 0,06428785 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01867143 0,06419175 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01867143 0,06409595 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01867143 0,06400042 ! reproductive behavior GO:0019098 12 7 0,000 0,01867143 0,06390518 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01867143 0,06381023 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01867143 0,06371555 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01867143 0,06362116 ! oligopeptide transport GO:0006857 11 7 0,000 0,01867143 0,06352705 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01867143 0,06343321 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01867143 0,06333965 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,01867143 0,06324637 ! pericardium development GO:0060039 8 7 0,000 0,01867143 0,06315336 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01867143 0,06306062 ! fibril organization GO:0043206 13 7 0,000 0,01867143 0,06296816 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01867143 0,06287596 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01867143 0,06278404 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01867143 0,06269238 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01867143 0,062601 ! lipoprotein transport GO:0042953 9 7 0,000 0,01867143 0,06250987 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01867143 0,06241902 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01867143 0,06232842 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01867143 0,06223809 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01867143 0,06214802 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01867143 0,06205821 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01867143 0,06196866 ! chemosensory behavior GO:0007635 9 7 0,000 0,01867143 0,06187937 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01867143 0,06179034 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01867143 0,06170156 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01867143 0,06161303 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01867143 0,06152476 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01867143 0,06143674 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01867143 0,06134898 ! reflex GO:0060004 12 7 0,000 0,01867143 0,06126146 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01867143 0,06117419 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01867143 0,06108717 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01867143 0,0610004 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01867143 0,06091388 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01867143 0,0608276 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01867143 0,06074156 ! spinal cord patterning GO:0021511 7 7 0,000 0,01867143 0,06065577 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01867143 0,06057022 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01867143 0,06048491 ! adrenal gland development GO:0030325 17 7 0,000 0,01867143 0,06039984 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01867143 0,060315 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01867143 0,06023041 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01867143 0,06014606 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01867143 0,06006193 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01867143 0,05997805 ! endosome organization GO:0007032 10 7 0,000 0,01867143 0,0598944 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01867143 0,05981098 ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01867143 0,05972779 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01867143 0,05964484 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01867143 0,05956211 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01867143 0,05947962 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01867143 0,05939735 ! galactose metabolic process GO:0006012 10 7 0,000 0,01867143 0,05931531 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01867143 0,05923349 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01867143 0,05915191 ! organ growth GO:0035265 11 7 0,000 0,01867143 0,05907054 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01867143 0,0589894 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01867143 0,05890848 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01867143 0,05882779 ! retinol metabolic process GO:0042572 9 7 0,000 0,01867143 0,05874731 ! behavioral fear response GO:0001662 13 7 0,000 0,01867143 0,05866705 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01867143 0,05858702 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01867143 0,0585072 ! rRNA modification GO:0000154 12 7 0,000 0,01867143 0,0584276 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01867143 0,05834821 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01867143 0,05826904 ! response to UV-B GO:0010224 11 7 0,000 0,01867143 0,05819009 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01867143 0,05811134 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01867143 0,05803282 ! intermediate filament organization GO:0045109 11 7 0,000 0,01867143 0,0579545 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01867143 0,05787639 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01867143 0,0577985 ! fibrinolysis GO:0042730 9 7 0,000 0,01867143 0,05772081 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01867143 0,05764333 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01867143 0,05756606 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01867143 0,057489 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01867143 0,05741214 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01867143 0,05733549 ! response to tropane GO:0014073 13 7 0,000 0,01867143 0,05725904 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01867143 0,0571828 ! melanosome localization GO:0032400 10 7 0,000 0,01867143 0,05710676 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01867143 0,05703092 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01867143 0,05695528 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01867143 0,05687985 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01867143 0,05680461 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01867143 0,05672957 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01867143 0,05665473 ! mast cell activation GO:0045576 9 7 0,000 0,01867143 0,05658008 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01867143 0,05650564 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01867143 0,05643138 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01867143 0,05635733 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01867143 0,05628346 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01867143 0,05620979 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01867143 0,05613632 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01867143 0,05606303 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01867143 0,05598994 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01867143 0,05591704 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01867143 0,05584432 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01867143 0,0557718 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01867143 0,05569946 ! response to tumor cell GO:0002347 12 7 0,000 0,01867143 0,05562731 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01867143 0,05555535 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01867143 0,05548357 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01867143 0,05541198 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01867143 0,05534057 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01867143 0,05526935 ! diuresis GO:0030146 12 7 0,000 0,01867143 0,05519831 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01867143 0,05512745 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01867143 0,05505677 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01867143 0,05498628 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01867143 0,05491596 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01867143 0,05484583 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01867143 0,05477587 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01867143 0,05470609 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01867143 0,05463649 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01867143 0,05456707 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01867143 0,05449782 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01867143 0,05442875 ! lymph node development GO:0048535 9 7 0,000 0,01867143 0,05435985 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01867143 0,05429113 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01867143 0,05422258 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01867143 0,0541542 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01867143 0,054086 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01867143 0,05401797 ! ATP catabolic process GO:0006200 10 7 0,000 0,01867143 0,0539501 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01867143 0,05388241 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01867143 0,05381489 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01867143 0,05374754 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01867143 0,05368035 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01867143 0,05361334 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01867143 0,05354649 ! muscle adaptation GO:0043500 12 7 0,000 0,01867143 0,0534798 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01867143 0,05341329 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01867143 0,05334694 ! retina homeostasis GO:0001895 9 7 0,000 0,01867143 0,05328075 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01867143 0,05321473 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01867143 0,05314887 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01867143 0,05308317 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01867143 0,05301763 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01867143 0,05295226 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01867143 0,05288705 ! alcohol catabolic process GO:0046164 104 80 1,000 0,01956995 0,05536395 ! protein localization in nucleus GO:0034504 133 80 1,000 0,01956995 0,05529594 ! regulation of GTPase activity GO:0043087 129 80 1,000 0,01956995 0,05522809 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,02003143 0,05646114 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,02003143 0,05639204 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,02049747 0,05763347 GO:0060348|bone development, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,02096804 0,05888461 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02131077 0,0597741 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02131077 0,05970129 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,02131077 0,05962866 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02131077 0,05955621 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02131077 0,05948393 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02131077 0,05941183 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02131077 0,05933991 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02131077 0,05926815 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02131077 0,05919657 ! phosphate transport GO:0006817 10 8 0,000 0,02131077 0,05912517 ! N-glycan processing GO:0006491 12 8 0,000 0,02131077 0,05905393 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02131077 0,05898287 ! UTP metabolic process GO:0046051 8 8 0,000 0,02131077 0,05891197 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02131077 0,05884125 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02131077 0,0587707 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02131077 0,05870031 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02131077 0,0586301 ! succinate metabolic process GO:0006105 14 8 0,000 0,02131077 0,05856005 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,02131077 0,05849017 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02131077 0,05842046 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02131077 0,05835091 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02131077 0,05828152 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02131077 0,05821231 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02131077 0,05814325 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02131077 0,05807436 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02131077 0,05800564 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02131077 0,05793707 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02131077 0,05786867 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02131077 0,05780043 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02131077 0,05773235 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02131077 0,05766443 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02131077 0,05759667 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02131077 0,05752906 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02131077 0,05746162 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02131077 0,05739434 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02131077 0,05732721 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02131077 0,05726024 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02131077 0,05719342 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02131077 0,05712676 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02131077 0,05706026 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02131077 0,05699391 ! melanin metabolic process GO:0006582 12 8 0,000 0,02131077 0,05692771 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02131077 0,05686167 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02131077 0,05679578 ! macrophage activation GO:0042116 12 8 0,000 0,02131077 0,05673005 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02131077 0,05666446 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02131077 0,05659903 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02131077 0,05653375 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02131077 0,05646862 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02131077 0,05640364 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02131077 0,05633881 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02131077 0,05627412 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02131077 0,05620959 ! ruffle organization GO:0031529 11 8 0,000 0,02131077 0,0561452 ! osteoblast development GO:0002076 13 8 0,000 0,02131077 0,05608096 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02131077 0,05601687 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02131077 0,05595292 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02131077 0,05588912 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02131077 0,05582547 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02131077 0,05576196 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02131077 0,05569859 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02131077 0,05563537 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02131077 0,05557229 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02131077 0,05550936 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02131077 0,05544656 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02131077 0,05538391 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02131077 0,0553214 ! segment specification GO:0007379 10 8 0,000 0,02131077 0,05525903 ! cellular extravasation GO:0045123 11 8 0,000 0,02131077 0,0551968 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02131077 0,05513472 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02131077 0,05507277 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02131077 0,05501096 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,02131077 0,05494928 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02131077 0,05488775 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02131077 0,05482636 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02131077 0,0547651 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02131077 0,05470398 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02131077 0,05464299 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02131077 0,05458214 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02131077 0,05452143 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02131077 0,05446085 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02131077 0,0544004 ! icosanoid secretion GO:0032309 12 8 0,000 0,02131077 0,05434009 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02131077 0,05427991 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02131077 0,05421987 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02131077 0,05415996 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02131077 0,05410018 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02131077 0,05404053 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02131077 0,05398102 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02131077 0,05392163 ! sterol catabolic process GO:0016127 9 8 0,000 0,02131077 0,05386238 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02131077 0,05380325 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02131077 0,05374426 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02131077 0,05368539 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02131077 0,05362665 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02131077 0,05356805 ! prophase GO:0051324 11 8 0,000 0,02131077 0,05350957 ! S phase GO:0051320 8 8 0,000 0,02131077 0,05345121 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02131077 0,05339299 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02131077 0,05333489 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02131077 0,05327692 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02131077 0,05321907 ! hormone catabolic process GO:0042447 13 8 0,000 0,02131077 0,05316135 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02131077 0,05310375 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02131077 0,05304628 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02131077 0,05298893 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02131077 0,05293171 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02131077 0,05287461 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02131077 0,05281763 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02131077 0,05276078 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02131077 0,05270405 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02131077 0,05264744 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02131077 0,05259095 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02131077 0,05253458 ! regulation of embryonic development GO:0045995 16 8 0,000 0,02131077 0,05247833 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02131077 0,05242221 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02131077 0,0523662 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02131077 0,05231031 ! transcription initiation GO:0006352 118 85 1,000 0,02192268 0,05375497 ! regulation of protein localization GO:0032880 132 85 1,000 0,02192268 0,05369773 ! regulation of membrane potential GO:0042391 128 85 1,000 0,02192268 0,0536406 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,02192268 0,0535836 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,02289513 0,05590107 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,02289513 0,05584179 ! regulation of developmental growth GO:0048638 13 9 0,000 0,02394316 0,05833608 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,02394316 0,05827435 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02394316 0,05821275 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02394316 0,05815128 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02394316 0,05808994 ! CTP metabolic process GO:0046036 9 9 0,000 0,02394316 0,05802873 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02394316 0,05796764 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02394316 0,05790669 ! GTP metabolic process GO:0046039 9 9 0,000 0,02394316 0,05784586 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02394316 0,05778516 ! social behavior GO:0035176 14 9 0,000 0,02394316 0,05772459 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02394316 0,05766415 ! artery development GO:0060840 19 9 0,000 0,02394316 0,05760383 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02394316 0,05754364 ! regulation of glycolysis GO:0006110 15 9 0,000 0,02394316 0,05748357 ! response to pain GO:0048265 16 9 0,000 0,02394316 0,05742363 ! protein complex disassembly GO:0043241 17 9 0,000 0,02394316 0,05736381 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02394316 0,05730412 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02394316 0,05724455 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02394316 0,05718511 ! lung alveolus development GO:0048286 17 9 0,000 0,02394316 0,05712579 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02394316 0,05706659 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02394316 0,05700752 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02394316 0,05694856 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02394316 0,05688973 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02394316 0,05683102 ! protein targeting to ER GO:0045047 19 9 0,000 0,02394316 0,05677243 ! T cell selection GO:0045058 18 9 0,000 0,02394316 0,05671397 ! endoderm development GO:0007492 12 9 0,000 0,02394316 0,05665562 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02394316 0,05659739 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02394316 0,05653928 ! arginine catabolic process GO:0006527 10 9 0,000 0,02394316 0,05648129 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02394316 0,05642342 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02394316 0,05636567 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02394316 0,05630804 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02394316 0,05625052 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02394316 0,05619312 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02394316 0,05613584 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02394316 0,05607868 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02394316 0,05602163 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02394316 0,0559647 ! mannose metabolic process GO:0006013 9 9 0,000 0,02394316 0,05590788 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02394316 0,05585118 ! receptor clustering GO:0043113 15 9 0,000 0,02394316 0,05579459 ! epithelial cell development GO:0002064 10 9 0,000 0,02394316 0,05573812 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02394316 0,05568176 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02394316 0,05562552 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02394316 0,05556939 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02394316 0,05551337 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02394316 0,05545746 ! motor axon guidance GO:0008045 14 9 0,000 0,02394316 0,05540167 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02394316 0,05534599 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02394316 0,05529042 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02394316 0,05523497 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02394316 0,05517962 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02394316 0,05512439 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02394316 0,05506926 ! DNA ligation GO:0006266 14 9 0,000 0,02394316 0,05501425 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02394316 0,05495934 ! response to amine stimulus GO:0014075 13 9 0,000 0,02394316 0,05490455 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02394316 0,05484986 ! renal water homeostasis GO:0003091 14 9 0,000 0,02394316 0,05479528 ! postreplication repair GO:0006301 11 9 0,000 0,02394316 0,05474082 ! mRNA cleavage GO:0006379 13 9 0,000 0,02394316 0,05468646 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02394316 0,0546322 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02394316 0,05457806 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02394316 0,05452402 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02394316 0,05447009 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02394316 0,05441627 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02394316 0,05436255 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02394316 0,05430894 ! acid secretion GO:0046717 14 9 0,000 0,02394316 0,05425543 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02394316 0,05420203 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02394316 0,05414873 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02394316 0,05409554 ! purine base metabolic process GO:0006144 18 9 0,000 0,02394316 0,05404245 ! oocyte differentiation GO:0009994 12 9 0,000 0,02394316 0,05398947 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02394316 0,05393659 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02394316 0,05388382 ! spleen development GO:0048536 15 9 0,000 0,02394316 0,05383114 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02394316 0,05377857 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02394316 0,05372611 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02394316 0,05367374 ! detection of calcium ion GO:0005513 13 9 0,000 0,02394316 0,05362148 ! blastocyst formation GO:0001825 12 9 0,000 0,02394316 0,05356932 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02394316 0,05351726 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02394316 0,0534653 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02394316 0,05341344 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02394316 0,05336169 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02394316 0,05331003 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02394316 0,05325847 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02394316 0,05320702 ! prepulse inhibition GO:0060134 14 9 0,000 0,02394316 0,05315566 ! embryonic placenta development GO:0001892 12 9 0,000 0,02394316 0,0531044 ! insulin secretion GO:0030073 17 9 0,000 0,02394316 0,05305324 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02394316 0,05300218 ! response to nicotine GO:0035094 16 9 0,000 0,02394316 0,05295121 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02394316 0,05290035 ! nucleus localization GO:0051647 15 9 0,000 0,02394316 0,05284958 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02394316 0,05279891 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,02438676 0,05372562 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,02540283 0,05591054 ! cell fate commitment GO:0045165 141 92 1,000 0,02540283 0,05585709 ! sulfur metabolic process GO:0006790 118 92 1,000 0,02540283 0,05580374 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,02591729 0,05687955 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,02591729 0,05682533 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,02591729 0,05677121 ! carbohydrate catabolic process GO:0016052 121 93 1,000 0,02591729 0,0567172 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02656862 0,05808728 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02656862 0,05803212 ! neuron fate specification GO:0048665 11 10 0,000 0,02656862 0,05797706 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02656862 0,0579221 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02656862 0,05786725 ! thyroid gland development GO:0030878 19 10 0,000 0,02656862 0,05781251 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02656862 0,05775786 ! synapsis GO:0007129 13 10 0,000 0,02656862 0,05770332 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02656862 0,05764889 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02656862 0,05759455 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02656862 0,05754032 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02656862 0,05748619 ! sulfate transport GO:0008272 12 10 0,000 0,02656862 0,05743216 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02656862 0,05737823 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02656862 0,05732441 ! androgen metabolic process GO:0008209 13 10 0,000 0,02656862 0,05727068 ! phospholipid efflux GO:0033700 16 10 0,000 0,02656862 0,05721706 ! hippocampus development GO:0021766 19 10 0,000 0,02656862 0,05716354 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,02656862 0,05711011 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02656862 0,05705679 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02656862 0,05700356 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02656862 0,05695044 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02656862 0,05689741 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02656862 0,05684448 ! pathogenesis GO:0009405 13 10 0,000 0,02656862 0,05679165 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02656862 0,05673892 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02656862 0,05668629 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02656862 0,05663375 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02656862 0,05658131 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02656862 0,05652897 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02656862 0,05647673 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02656862 0,05642458 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02656862 0,05637253 GO:0050931|pigment cell differentiation, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02656862 0,05632057 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02656862 0,05626871 ! response to X-ray GO:0010165 16 10 0,000 0,02656862 0,05621695 ! B cell proliferation GO:0042100 14 10 0,000 0,02656862 0,05616528 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02656862 0,0561137 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02656862 0,05606222 ! forebrain cell migration GO:0021885 17 10 0,000 0,02656862 0,05601083 ! lipid digestion GO:0044241 15 10 0,000 0,02656862 0,05595954 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02656862 0,05590834 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02656862 0,05585724 ! UV protection GO:0009650 14 10 0,000 0,02656862 0,05580623 ! entry into host cell GO:0030260 20 10 0,000 0,02656862 0,05575531 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02656862 0,05570448 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02656862 0,05565375 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02656862 0,05560311 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02656862 0,05555256 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02656862 0,05550211 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02656862 0,05545174 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02656862 0,05540147 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02656862 0,05535129 ! regulation of organ growth GO:0046620 11 10 0,000 0,02656862 0,05530119 ! response to dsRNA GO:0043331 18 10 0,000 0,02656862 0,05525119 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02656862 0,05520128 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02656862 0,05515146 ! embryonic axis specification GO:0000578 12 10 0,000 0,02656862 0,05510173 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02656862 0,05505209 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02656862 0,05500254 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02656862 0,05495308 ! cranial nerve development GO:0021545 12 10 0,000 0,02656862 0,0549037 ! fucose catabolic process GO:0019317 16 10 0,000 0,02656862 0,05485442 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02656862 0,05480522 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02656862 0,05475611 ! protein sumoylation GO:0016925 12 10 0,000 0,02656862 0,05470709 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02656862 0,05465816 ! zymogen activation GO:0031638 14 10 0,000 0,02656862 0,05460931 ! salivary gland development GO:0007431 22 10 0,000 0,02656862 0,05456055 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02656862 0,05451188 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02656862 0,0544633 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02656862 0,0544148 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02656862 0,05436639 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02656862 0,05431806 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02656862 0,05426982 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02656862 0,05422167 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02656862 0,0541736 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02656862 0,05412562 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02656862 0,05407772 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02656862 0,0540299 ! detection of bacterium GO:0016045 10 10 0,000 0,02656862 0,05398217 ! embryonic gut development GO:0048566 11 10 0,000 0,02656862 0,05393453 ! activation of innate immune response GO:0002218 10 10 0,000 0,02656862 0,05388697 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02656862 0,05383949 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02656862 0,05379209 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02656862 0,05374478 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02656862 0,05369756 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02656862 0,05365041 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02656862 0,05360335 ! angiogenesis GO:0001525 149 95 1,000 0,02695892 0,05434314 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,02748604 0,05535718 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,02748604 0,05530875 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,02748604 0,0552604 ! calcium ion transport GO:0006816 167 99 1,000 0,02909232 0,05843873 ! protein import GO:0017038 156 99 1,000 0,02909232 0,05838773 ! rRNA transcription GO:0009303 17 11 0,000 0,02918717 0,05852701 ! respiratory burst GO:0045730 14 11 0,000 0,02918717 0,05847603 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02918717 0,05842514 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02918717 0,05837433 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02918717 0,05832361 ! virus-host interaction GO:0019048 17 11 0,000 0,02918717 0,05827299 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02918717 0,05822245 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02918717 0,05817199 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02918717 0,05812163 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02918717 0,05807135 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02918717 0,05802116 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02918717 0,05797105 ! mating GO:0007618 14 11 0,000 0,02918717 0,05792104 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02918717 0,0578711 ! T cell proliferation GO:0042098 20 11 0,000 0,02918717 0,05782126 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02918717 0,0577715 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02918717 0,05772182 ! bone resorption GO:0045453 16 11 0,000 0,02918717 0,05767223 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02918717 0,05762273 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02918717 0,05757331 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02918717 0,05752398 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02918717 0,05747473 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02918717 0,05742556 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02918717 0,05737648 ! syncytium formation GO:0006949 15 11 0,000 0,02918717 0,05732748 ! plasma membrane organization GO:0007009 18 11 0,000 0,02918717 0,05727857 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02918717 0,05722974 ! focal adhesion formation GO:0048041 24 11 0,000 0,02918717 0,05718099 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02918717 0,05713232 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02918717 0,05708374 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02918717 0,05703524 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02918717 0,05698683 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02918717 0,05693849 ! adult heart development GO:0007512 11 11 0,000 0,02918717 0,05689024 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02918717 0,05684207 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02918717 0,05679398 ! temperature homeostasis GO:0001659 16 11 0,000 0,02918717 0,05674597 ! L-glutamate transport GO:0015813 16 11 0,000 0,02918717 0,05669804 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02918717 0,05665019 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02918717 0,05660243 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02918717 0,05655474 ! stem cell development GO:0048864 29 11 0,000 0,02918717 0,05650714 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02918717 0,05645961 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02918717 0,05641217 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02918717 0,0563648 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02918717 0,05631752 ! vasoconstriction GO:0042310 15 11 0,000 0,02918717 0,05627031 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02918717 0,05622318 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02918717 0,05617613 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02918717 0,05612916 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02918717 0,05608227 ! ribosome assembly GO:0042255 13 11 0,000 0,02918717 0,05603546 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02918717 0,05598872 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02918717 0,05594207 ! chromatin silencing GO:0006342 19 11 0,000 0,02918717 0,05589549 ! nucleosome positioning GO:0016584 13 11 0,000 0,02918717 0,05584899 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02918717 0,05580256 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02918717 0,05575621 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02918717 0,05570994 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02918717 0,05566375 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02918717 0,05561763 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02918717 0,05557159 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02918717 0,05552563 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02918717 0,05547974 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02918717 0,05543392 ! male genitalia development GO:0030539 13 11 0,000 0,02918717 0,05538819 ! cholesterol efflux GO:0033344 19 11 0,000 0,02918717 0,05534252 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02918717 0,05529694 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02918717 0,05525142 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02918717 0,05520599 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02918717 0,05516063 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02918717 0,05511534 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02918717 0,05507012 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02918717 0,05502498 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02918717 0,05497992 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02918717 0,05493493 ! lysogeny GO:0030069 18 11 0,000 0,02918717 0,05489001 GO:0019047|provirus integration, ! acrosome reaction GO:0007340 13 11 0,000 0,02918717 0,05484516 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02918717 0,05480039 ! regulation of translation GO:0006417 151 100 1,000 0,02963597 0,05559766 ! divalent metal ion transport GO:0070838 171 100 1,000 0,02963597 0,05555235 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,02963597 0,05550711 ! protein localization in organelle GO:0033365 161 100 1,000 0,02963597 0,05546195 ! lactation GO:0007595 20 12 0,000 0,03179882 0,05946121 ! reproductive cellular process GO:0048610 14 12 0,000 0,03179882 0,0594129 ! tRNA modification GO:0006400 14 12 0,000 0,03179882 0,05936468 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03179882 0,05931653 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03179882 0,05926846 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03179882 0,05922047 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03179882 0,05917256 ! non-recombinational repair GO:0000726 19 12 0,000 0,03179882 0,05912472 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03179882 0,05907697 ! peroxisomal transport GO:0043574 21 12 0,000 0,03179882 0,05902929 ! cartilage condensation GO:0001502 18 12 0,000 0,03179882 0,05898168 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03179882 0,05893415 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03179882 0,0588867 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03179882 0,05883933 ! heart looping GO:0001947 15 12 0,000 0,03179882 0,05879203 ! palate development GO:0060021 15 12 0,000 0,03179882 0,05874481 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03179882 0,05869766 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03179882 0,05865059 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03179882 0,05860359 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03179882 0,05855667 ! arginine metabolic process GO:0006525 13 12 0,000 0,03179882 0,05850983 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,03179882 0,05846306 ! methionine metabolic process GO:0006555 13 12 0,000 0,03179882 0,05841636 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03179882 0,05836974 ! Golgi organization GO:0007030 18 12 0,000 0,03179882 0,05832319 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03179882 0,05827672 ! monoamine transport GO:0015844 13 12 0,000 0,03179882 0,05823032 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03179882 0,058184 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,03179882 0,05813775 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03179882 0,05809157 ! L-amino acid transport GO:0015807 20 12 0,000 0,03179882 0,05804546 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03179882 0,05799943 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03179882 0,05795347 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03179882 0,05790759 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03179882 0,05786178 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03179882 0,05781604 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03179882 0,05777037 ! cerebellum development GO:0021549 13 12 0,000 0,03179882 0,05772477 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03179882 0,05767925 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03179882 0,05763379 ! histone acetylation GO:0016573 23 12 0,000 0,03179882 0,05758841 ! histone methylation GO:0016571 15 12 0,000 0,03179882 0,0575431 ! autonomic nervous system development GO:0048483 23 12 0,000 0,03179882 0,05749787 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03179882 0,0574527 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,03179882 0,0574076 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03179882 0,05736258 ! response to gamma radiation GO:0010332 20 12 0,000 0,03179882 0,05731762 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03179882 0,05727274 ! intestinal absorption GO:0050892 19 12 0,000 0,03179882 0,05722792 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03179882 0,05718318 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03179882 0,0571385 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03179882 0,0570939 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03179882 0,05704936 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03179882 0,0570049 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03179882 0,0569605 ! microspike assembly GO:0030035 23 12 0,000 0,03179882 0,05691617 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03179882 0,05687192 ! response to cold GO:0009409 14 12 0,000 0,03179882 0,05682773 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,0344036 0,06143499 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,0344036 0,06138733 ! cGMP metabolic process GO:0046068 16 13 0,000 0,0344036 0,06133975 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,0344036 0,06129223 ! water transport GO:0006833 17 13 0,000 0,0344036 0,06124479 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,0344036 0,06119743 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,0344036 0,06115013 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,0344036 0,06110291 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,0344036 0,06105577 ! endocrine pancreas development GO:0031018 19 13 0,000 0,0344036 0,06100869 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,0344036 0,06096169 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,0344036 0,06091476 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,0344036 0,0608679 ! response to hexose stimulus GO:0009746 19 13 0,000 0,0344036 0,06082112 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,0344036 0,0607744 ! glutamate metabolic process GO:0006536 18 13 0,000 0,0344036 0,06072776 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,0344036 0,06068119 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,0344036 0,06063469 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,0344036 0,06058826 ! NAD metabolic process GO:0019674 21 13 0,000 0,0344036 0,06054191 ! exocrine system development GO:0035272 27 13 0,000 0,0344036 0,06049562 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,0344036 0,06044941 ! bone mineralization GO:0030282 15 13 0,000 0,0344036 0,06040326 ! regulation of exocytosis GO:0017157 17 13 0,000 0,0344036 0,06035719 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,0344036 0,06031118 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,0344036 0,06026525 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,0344036 0,06021938 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,0344036 0,06017359 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,0344036 0,06012787 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,0344036 0,06008221 ! genitalia development GO:0048806 15 13 0,000 0,0344036 0,06003663 ! regulation of cellular pH GO:0030641 20 13 0,000 0,0344036 0,05999111 ! cellular pigmentation GO:0033059 24 13 0,000 0,0344036 0,05994566 ! tissue regeneration GO:0042246 21 13 0,000 0,0344036 0,05990028 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,0344036 0,05985497 ! cofactor transport GO:0051181 19 13 0,000 0,0344036 0,05980973 ! NADP metabolic process GO:0006739 18 13 0,000 0,0344036 0,05976456 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,0344036 0,05971945 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,0344036 0,05967441 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,0344036 0,05962944 ! gas transport GO:0015669 18 13 0,000 0,0344036 0,05958454 ! regulation of RNA stability GO:0043487 28 13 0,000 0,0344036 0,05953971 ! heme biosynthetic process GO:0006783 20 13 0,000 0,0344036 0,05949494 ! regulation of axon extension GO:0030516 23 13 0,000 0,0344036 0,05945024 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,0344036 0,05940561 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,0344036 0,05936104 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,0344036 0,05931655 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,0344036 0,05927211 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,03700151 0,06370021 ! superoxide anion generation GO:0042554 18 14 0,000 0,03700151 0,06365257 ! neuron maturation GO:0042551 21 14 0,000 0,03700151 0,063605 ! regulation of S phase GO:0033261 18 14 0,000 0,03700151 0,06355749 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,03700151 0,06351006 ! myotube differentiation GO:0014902 21 14 0,000 0,03700151 0,0634627 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,03700151 0,06341541 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,03700151 0,06336819 ! inositol metabolic process GO:0006020 20 14 0,000 0,03700151 0,06332104 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,03700151 0,06327397 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,03700151 0,06322696 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,03700151 0,06318002 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,03700151 0,06313315 ! gene silencing by RNA GO:0031047 20 14 0,000 0,03700151 0,06308635 ! response to cAMP GO:0051591 19 14 0,000 0,03700151 0,06303962 ! limbic system development GO:0021761 25 14 0,000 0,03700151 0,06299296 ! startle response GO:0001964 21 14 0,000 0,03700151 0,06294636 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,03700151 0,06289984 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,03700151 0,06285339 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,03700151 0,062807 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,03700151 0,06276068 ! glycine metabolic process GO:0006544 22 14 0,000 0,03700151 0,06271443 ! pituitary gland development GO:0021983 23 14 0,000 0,03700151 0,06266825 ! cellular response to starvation GO:0009267 21 14 0,000 0,03700151 0,06262214 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,03700151 0,06257609 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,03700151 0,06253011 ! regulation of heart rate GO:0002027 23 14 0,000 0,03700151 0,0624842 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,03700151 0,06243836 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,03700151 0,06239258 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,03700151 0,06234687 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,03700151 0,06230123 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,03700151 0,06225566 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,03700151 0,06221015 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,03700151 0,06216471 ! axon cargo transport GO:0008088 27 14 0,000 0,03700151 0,06211933 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,03700151 0,06207402 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,03700151 0,06202878 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,03700151 0,0619836 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03700151 0,06193849 ! mRNA splice site selection GO:0006376 26 14 0,000 0,03700151 0,06189344 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,03700151 0,06184846 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,03700151 0,06180355 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,03700151 0,0617587 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,03700151 0,06171391 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,03700151 0,06166919 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,03700151 0,06162454 ! muscle maintenance GO:0046716 19 14 0,000 0,03700151 0,06157994 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,03700151 0,06153542 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,03700151 0,06149096 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,03700151 0,06144656 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,03700151 0,06140222 ! cell killing GO:0001906 20 14 0,000 0,03700151 0,06135795 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,03700151 0,06131375 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,03700151 0,06126961 ! cilium assembly GO:0042384 20 14 0,000 0,03700151 0,06122553 ! peptide hormone secretion GO:0030072 23 14 0,000 0,03700151 0,06118151 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03959259 0,06541879 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03959259 0,06537183 ! metencephalon development GO:0022037 19 15 0,000 0,03959259 0,06532494 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03959259 0,06527811 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03959259 0,06523135 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03959259 0,06518465 ! skin development GO:0043588 25 15 0,000 0,03959259 0,06513803 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03959259 0,06509147 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03959259 0,06504497 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03959259 0,06499854 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03959259 0,06495218 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03959259 0,06490589 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03959259 0,06485966 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03959259 0,06481349 ! adult walking behavior GO:0007628 25 15 0,000 0,03959259 0,0647674 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03959259 0,06472136 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03959259 0,0646754 ! myoblast differentiation GO:0045445 27 15 0,000 0,03959259 0,0646295 ! centrosome cycle GO:0007098 16 15 0,000 0,03959259 0,06458366 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03959259 0,06453789 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03959259 0,06449218 ! cerebral cortex development GO:0021987 29 15 0,000 0,03959259 0,06444654 ! response to osmotic stress GO:0006970 22 15 0,000 0,03959259 0,06440096 ! vesicle coating GO:0006901 25 15 0,000 0,03959259 0,06435545 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03959259 0,06431 ! DNA integration GO:0015074 22 15 0,000 0,03959259 0,06426462 ! peptide secretion GO:0002790 27 15 0,000 0,03959259 0,06421929 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03959259 0,06417404 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,03959259 0,06412885 ! neuron recognition GO:0008038 22 15 0,000 0,03959259 0,06408372 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03959259 0,06403865 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03959259 0,06399365 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03959259 0,06394871 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03959259 0,06390383 ! biomineral formation GO:0031214 18 15 0,000 0,03959259 0,06385902 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03959259 0,06381427 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03959259 0,06376958 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03959259 0,06372495 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03959259 0,06368039 ! organic cation transport GO:0015695 19 15 0,000 0,03959259 0,06363589 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03959259 0,06359145 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03959259 0,06354708 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03959259 0,06350276 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03959259 0,06345851 ! defense response to virus GO:0051607 27 15 0,000 0,03959259 0,06341432 ! peptide hormone processing GO:0016486 19 15 0,000 0,03959259 0,06337019 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03959259 0,06332612 ! protein secretion GO:0009306 27 16 0,000 0,04217684 0,06741261 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,04217684 0,06736579 ! hormone secretion GO:0046879 25 16 0,000 0,04217684 0,06731904 ! bone remodeling GO:0046849 24 16 0,000 0,04217684 0,06727236 ! endothelial cell migration GO:0043542 22 16 0,000 0,04217684 0,06722574 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04217684 0,06717918 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,04217684 0,06713269 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04217684 0,06708627 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04217684 0,0670399 ! glial cell development GO:0021782 24 16 0,000 0,04217684 0,06699361 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04217684 0,06694737 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04217684 0,0669012 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04217684 0,06685509 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04217684 0,06680905 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04217684 0,06676307 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04217684 0,06671715 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04217684 0,0666713 ! fructose metabolic process GO:0006000 20 16 0,000 0,04217684 0,06662551 ! regulation of protein binding GO:0043393 27 16 0,000 0,04217684 0,06657978 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04217684 0,06653412 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04217684 0,06648851 ! protein export from nucleus GO:0006611 24 16 0,000 0,04217684 0,06644297 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04217684 0,0663975 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04217684 0,06635208 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04217684 0,06630673 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04217684 0,06626144 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04217684 0,06621621 ! diencephalon development GO:0021536 25 16 0,000 0,04217684 0,06617104 ! oogenesis GO:0048477 23 16 0,000 0,04217684 0,06612593 ! neural crest cell migration GO:0001755 24 16 0,000 0,04217684 0,06608089 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04217684 0,0660359 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04217684 0,06599098 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04217684 0,06594612 ! steroid catabolic process GO:0006706 22 16 0,000 0,04217684 0,06590132 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04217684 0,06585658 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,04217684 0,0658119 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,04217684 0,06576728 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04217684 0,06572272 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04217684 0,06567823 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04217684 0,06563379 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04217684 0,06558941 ! nerve development GO:0021675 18 16 0,000 0,04217684 0,0655451 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04217684 0,06550084 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04217684 0,06545664 ! negative regulation of translation GO:0017148 22 16 0,000 0,04217684 0,0654125 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,04475429 0,06936312 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,04475429 0,06931641 ! negative regulation of defense response GO:0031348 19 17 0,000 0,04475429 0,06926976 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,04475429 0,06922318 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,04475429 0,06917666 ! glycerol metabolic process GO:0006071 20 17 0,000 0,04475429 0,0691302 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,04475429 0,06908381 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,04475429 0,06903747 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,04475429 0,0689912 ! signal complex assembly GO:0007172 29 17 0,000 0,04475429 0,06894499 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,04475429 0,06889884 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,04475429 0,06885276 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,04475429 0,06880673 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,04475429 0,06876077 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,04475429 0,06871487 ! memory GO:0007613 25 17 0,000 0,04475429 0,06866903 ! keratinization GO:0031424 17 17 0,000 0,04475429 0,06862325 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,04475429 0,06857753 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,04475429 0,06853187 ! retinoid metabolic process GO:0001523 22 17 0,000 0,04475429 0,06848627 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,04475429 0,06844074 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,04475429 0,06839526 ! vacuolar transport GO:0007034 24 17 0,000 0,04475429 0,06834985 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,04475429 0,06830449 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,04475429 0,0682592 ! membrane budding GO:0006900 29 17 0,000 0,04475429 0,06821396 ! heme metabolic process GO:0042168 27 17 0,000 0,04475429 0,06816879 ! actin filament bundle formation GO:0051017 26 17 0,000 0,04475429 0,06812367 ! neuromuscular junction development GO:0007528 23 17 0,000 0,04475429 0,06807862 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,04475429 0,06803362 ! body fluid secretion GO:0007589 27 17 0,000 0,04475429 0,06798869 ! stem cell differentiation GO:0048863 36 17 0,000 0,04475429 0,06794381 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,04475429 0,06789899 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,04475429 0,06785423 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,04475429 0,06780953 ! sensory perception of pain GO:0019233 23 17 0,000 0,04475429 0,06776489 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,04475429 0,06772031 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,04475429 0,06767579 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,04475429 0,06763132 ! synaptogenesis GO:0007416 24 17 0,000 0,04475429 0,06758691 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,04475429 0,06754257 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,04475429 0,06749828 ! cell-cell junction organization GO:0045216 25 17 0,000 0,04475429 0,06745404 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,04475429 0,06740987 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,04475429 0,06736575 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,04475429 0,06732169 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,04475429 0,06727769 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,04475429 0,06723375 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,04475429 0,06718986 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,04732495 0,07100286 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,04732495 0,07095657 ! positive regulation of translation GO:0045727 28 18 0,000 0,04732495 0,07091035 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,04732495 0,07086418 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,04732495 0,07081808 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,04732495 0,07077203 ! cAMP metabolic process GO:0046058 33 18 0,000 0,04732495 0,07072605 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,04732495 0,07068012 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,04732495 0,07063425 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,04732495 0,07058845 ! axis specification GO:0009798 26 18 0,000 0,04732495 0,0705427 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,04732495 0,07049701 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,04732495 0,07045138 ! pancreas development GO:0031016 26 18 0,000 0,04732495 0,07040581 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,04732495 0,0703603 ! glutamine metabolic process GO:0006541 23 18 0,000 0,04732495 0,07031485 ! response to retinoic acid GO:0032526 25 18 0,000 0,04732495 0,07026945 ! pigmentation during development GO:0048066 31 18 0,000 0,04732495 0,07022412 ! central nervous system neuron development GO:0021954 30 18 0,000 0,04732495 0,07017884 ! fucose metabolic process GO:0006004 26 18 0,000 0,04732495 0,07013362 ! response to fungus GO:0009620 19 18 0,000 0,04732495 0,07008846 ! peptide cross-linking GO:0018149 31 18 0,000 0,04732495 0,07004336 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,04732495 0,06999832 ! heart process GO:0003015 27 18 0,000 0,04732495 0,06995333 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,04732495 0,0699084 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,04732495 0,06986353 ! visual learning GO:0008542 35 18 0,000 0,04732495 0,06981872 ! somitogenesis GO:0001756 24 18 0,000 0,04732495 0,06977396 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,04732495 0,06972927 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,04732495 0,06968462 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,04732495 0,06964004 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,04732495 0,06959551 ! vitamin transport GO:0051180 24 18 0,000 0,04732495 0,06955104 ! hormone transport GO:0009914 27 18 0,000 0,04732495 0,06950663 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,04732495 0,06946227 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,04732495 0,06941797 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,04732495 0,06937373 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,04732495 0,06932954 ! cell-cell recognition GO:0009988 20 18 0,000 0,04732495 0,06928541 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,04732495 0,06924134 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,04732495 0,06919732 ! regulation of glucose import GO:0046324 21 18 0,000 0,04732495 0,06915336 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,04732495 0,06910945 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,04732495 0,0690656 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,04732495 0,0690218 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,04732495 0,06897806 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,04988884 0,07266898 ! positive regulation of ossification GO:0045778 30 19 0,000 0,04988884 0,07262299 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,04988884 0,07257706 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,04988884 0,07253118 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,04988884 0,07248536 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,04988884 0,0724396 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,04988884 0,0723939 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,04988884 0,07234825 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,04988884 0,07230266 ! regeneration GO:0031099 32 19 0,000 0,04988884 0,07225713 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,04988884 0,07221166 ! response to alkaloid GO:0043279 32 19 0,000 0,04988884 0,07216624 ! sensory perception of taste GO:0050909 23 19 0,000 0,04988884 0,07212088 ! smooth muscle contraction GO:0006939 36 19 0,000 0,04988884 0,07207558 ! peroxisome organization GO:0007031 29 19 0,000 0,04988884 0,07203034 ! digestive system process GO:0022600 30 19 0,000 0,04988884 0,07198515 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,04988884 0,07194002 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,04988884 0,07189494 ! response to vitamin A GO:0033189 26 19 0,000 0,04988884 0,07184992 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,04988884 0,07180496 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,04988884 0,07176005 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,04988884 0,0717152 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,04988884 0,07167041 ! response to starvation GO:0042594 30 19 0,000 0,04988884 0,07162567 ! sex determination GO:0007530 29 19 0,000 0,04988884 0,07158099 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,04988884 0,07153636 ! plasma membrane fusion GO:0045026 23 19 0,000 0,04988884 0,07149179 ! cytolysis GO:0019835 20 19 0,000 0,04988884 0,07144728 ! renal system process GO:0003014 35 19 0,000 0,04988884 0,07140282 ! vasodilation GO:0042311 33 19 0,000 0,04988884 0,07135841 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,04988884 0,07131406 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,04988884 0,07126977 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,04988884 0,07122553 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,04988884 0,07118134 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,04988884 0,07113721 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,04988884 0,07109314 ! sarcomere organization GO:0045214 23 19 0,000 0,04988884 0,07104912 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,04988884 0,07100515 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,04988884 0,07096124 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,04988884 0,07091738 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,04988884 0,07087358 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,04988884 0,07082983 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,04988884 0,07078614 ! protein stabilization GO:0050821 26 19 0,000 0,04988884 0,07074249 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,05244597 0,07432269 ! iron ion transport GO:0006826 37 20 0,000 0,05244597 0,07427693 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,05244597 0,07423122 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,05244597 0,07418557 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,05244597 0,07413997 ! response to vitamin GO:0033273 29 20 0,000 0,05244597 0,07409443 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,05244597 0,07404895 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,05244597 0,07400352 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,05244597 0,07395814 ! spinal cord development GO:0021510 31 20 0,000 0,05244597 0,07391283 ! response to ethanol GO:0045471 37 20 0,000 0,05244597 0,07386756 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,05244597 0,07382236 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,05244597 0,07377721 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,05244597 0,07373211 ! chromosome condensation GO:0030261 31 20 0,000 0,05244597 0,07368707 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,05244597 0,07364208 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,05244597 0,07359715 ! pallium development GO:0021543 38 20 0,000 0,05244597 0,07355228 ! DNA modification GO:0006304 28 20 0,000 0,05244597 0,07350745 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,05244597 0,07346269 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,05244597 0,07341797 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,05244597 0,07337332 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,05244597 0,07332871 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,05244597 0,07328416 ! collagen catabolic process GO:0030574 25 20 0,000 0,05244597 0,07323967 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,05244597 0,07319523 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,05244597 0,07315084 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,05244597 0,0731065 ! alditol metabolic process GO:0019400 24 20 0,000 0,05244597 0,07306222 ! actin filament-based movement GO:0030048 34 20 0,000 0,05244597 0,073018 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,05499637 0,07652247 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,05499637 0,07647621 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,05499637 0,07643 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,05499637 0,07638384 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,05499637 0,07633775 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,05499637 0,0762917 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,05499637 0,07624572 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,05499637 0,07619979 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,05499637 0,07615391 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,05499637 0,07610809 ! protein amino acid acylation GO:0043543 37 21 0,000 0,05499637 0,07606232 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,05499637 0,07601661 ! phototransduction GO:0007602 25 21 0,000 0,05499637 0,07597096 ! dendrite development GO:0016358 35 21 0,000 0,05499637 0,07592536 ! visual behavior GO:0007632 39 21 0,000 0,05499637 0,07587981 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,05499637 0,07583432 ! ovarian follicle development GO:0001541 30 21 0,000 0,05499637 0,07578888 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,05499637 0,0757435 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,05499637 0,07569817 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,05499637 0,0756529 ! cell aging GO:0007569 32 21 0,000 0,05499637 0,07560768 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,05499637 0,07556251 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,05499637 0,0755174 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,05499637 0,07547234 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,05499637 0,07542734 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,05499637 0,07538239 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,05499637 0,07533749 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,05499637 0,07529265 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,05499637 0,07524786 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,05499637 0,07520312 ! fatty acid transport GO:0015908 30 21 0,000 0,05499637 0,07515844 ! immunoglobulin production GO:0002377 33 21 0,000 0,05499637 0,0751138 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,05499637 0,07506923 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,05499637 0,0750247 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,05499637 0,07498023 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,05499637 0,07493581 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,05499637 0,07489144 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,05499637 0,07484713 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,05499637 0,07480287 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,05499637 0,07475866 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,05499637 0,0747145 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,05499637 0,07467039 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,05499637 0,07462634 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,05499637 0,07458234 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,05499637 0,07453839 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,05499637 0,07449449 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,05754005 0,07789412 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,05754005 0,0778483 ! viral genome replication GO:0019079 29 22 0,000 0,05754005 0,07780253 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,05754005 0,07775682 ! leukocyte adhesion GO:0007159 38 22 0,000 0,05754005 0,07771116 ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,05754005 0,07766556 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,05754005 0,07762 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,05754005 0,07757451 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,05754005 0,07752906 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,05754005 0,07748367 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,05754005 0,07743833 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,05754005 0,07739304 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,05754005 0,07734781 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,05754005 0,07730263 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,05754005 0,07725751 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,05754005 0,07721243 ! regulation of behavior GO:0050795 38 22 0,000 0,05754005 0,07716741 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,05754005 0,07712244 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,05754005 0,07707752 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,05754005 0,07703266 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,05754005 0,07698785 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,05754005 0,07694309 ! blastocyst development GO:0001824 37 22 0,000 0,05754005 0,07689838 ! neural tube closure GO:0001843 33 22 0,000 0,05754005 0,07685372 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,05754005 0,07680912 ! protein tetramerization GO:0051262 39 22 0,000 0,05754005 0,07676456 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06007702 0,0801027 ! neuron fate commitment GO:0048663 32 23 0,000 0,06007702 0,08005629 ! embryonic pattern specification GO:0009880 31 23 0,000 0,06007702 0,08000993 ! myelination GO:0042552 35 23 0,000 0,06007702 0,07996363 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06007702 0,07991738 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06007702 0,07987119 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,06007702 0,07982505 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,06007702 0,07977896 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,06007702 0,07973292 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,06007702 0,07968694 ! vesicle targeting GO:0006903 32 23 0,000 0,06007702 0,07964101 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06007702 0,07959513 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,06007702 0,07954931 ! osteoblast differentiation GO:0001649 40 23 0,000 0,06007702 0,07950354 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06007702 0,07945782 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06007702 0,07941216 ! interaction with host GO:0051701 37 23 0,000 0,06007702 0,07936654 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06007702 0,07932098 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,06007702 0,07927548 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,06007702 0,07923002 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,06007702 0,07918462 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,06007702 0,07913926 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06007702 0,07909396 ! cell fate determination GO:0001709 45 23 0,000 0,06007702 0,07904872 ! pentose metabolic process GO:0019321 31 23 0,000 0,06007702 0,07900352 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,06007702 0,07895837 ! spermatid development GO:0007286 33 23 0,000 0,06007702 0,07891328 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06007702 0,07886824 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06007702 0,07882325 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06007702 0,07877831 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06007702 0,07873342 ! telomere organization GO:0032200 32 23 0,000 0,06007702 0,07868858 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,06007702 0,0786438 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06007702 0,07859906 ! regulation of amine transport GO:0051952 38 23 0,000 0,06007702 0,07855438 ! liver development GO:0001889 40 23 0,000 0,06007702 0,07850975 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,06260732 0,08176992 ! initiation of viral infection GO:0019059 42 24 0,000 0,06260732 0,08172351 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,06260732 0,08167716 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,06260732 0,08163085 ! superoxide metabolic process GO:0006801 32 24 0,000 0,06260732 0,0815846 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,06260732 0,08153841 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,06260732 0,08149226 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,06260732 0,08144617 ! sperm motility GO:0030317 27 24 0,000 0,06260732 0,08140013 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,06260732 0,08135414 ! vacuole organization GO:0007033 39 24 0,000 0,06260732 0,0813082 ! receptor metabolic process GO:0043112 37 24 0,000 0,06260732 0,08126232 ! neural crest cell development GO:0014032 39 24 0,000 0,06260732 0,08121648 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,06260732 0,0811707 ! primary neural tube formation GO:0014020 35 24 0,000 0,06260732 0,08112497 ! negative regulation of cell development GO:0010721 56 24 0,000 0,06260732 0,08107929 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,06260732 0,08103367 ! base-excision repair GO:0006284 31 24 0,000 0,06260732 0,08098809 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,06260732 0,08094257 GO:0002708|positive regulation of lymphocyte mediated immunity, ! neurotransmitter secretion GO:0007269 32 24 0,000 0,06260732 0,08089709 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,06260732 0,08085167 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,06513094 0,08406351 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,06513094 0,08401636 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,06513094 0,08396926 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,06513094 0,08392222 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,06513094 0,08387523 ! peptide transport GO:0015833 43 25 0,000 0,06513094 0,0838283 ! male gonad development GO:0008584 33 25 0,000 0,06513094 0,08378141 ! iron ion homeostasis GO:0055072 39 25 0,000 0,06513094 0,08373458 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,06513094 0,0836878 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,06513094 0,08364108 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,06513094 0,0835944 ! phospholipid transport GO:0015914 35 25 0,000 0,06513094 0,08354778 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,06513094 0,08350121 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,06513094 0,08345469 ! detection of light stimulus GO:0009583 30 25 0,000 0,06513094 0,08340822 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,06513094 0,08336181 ! leukocyte proliferation GO:0070661 39 25 0,000 0,06513094 0,08331544 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,06513094 0,08326913 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,06764792 0,08643901 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,06764792 0,08639101 ! translational initiation GO:0006413 43 26 0,000 0,06764792 0,08634307 ! regulation of pH GO:0006885 36 26 0,000 0,06764792 0,08629518 ! circadian rhythm GO:0007623 42 26 0,000 0,06764792 0,08624734 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,06764792 0,08619956 ! post-embryonic development GO:0009791 42 26 0,000 0,06764792 0,08615183 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,06764792 0,08610416 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,06764792 0,08605653 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,06764792 0,08600896 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,06764792 0,08596144 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,06764792 0,08591398 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,06764792 0,08586656 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,07015826 0,08900386 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,07015826 0,0889548 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,07015826 0,08890578 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,07015826 0,08885683 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,07015826 0,08880792 ! catechol metabolic process GO:0009712 43 27 0,000 0,07015826 0,08875908 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,07015826 0,08871028 ! acute-phase response GO:0006953 42 27 0,000 0,07015826 0,08866154 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,07015826 0,08861285 ! myofibril assembly GO:0030239 36 27 0,000 0,07015826 0,08856421 GO:0055002|striated muscle cell development, ! response to ionizing radiation GO:0010212 47 27 0,000 0,07015826 0,08851563 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,07015826 0,0884671 ! natural killer cell activation GO:0030101 35 27 0,000 0,07015826 0,08841863 ! lipid oxidation GO:0034440 38 27 0,000 0,07015826 0,08837021 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,07015826 0,08832184 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,07015826 0,08827352 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,07015826 0,08822526 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,07015826 0,08817705 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,07015826 0,08812889 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,07015826 0,08808079 ! gene silencing GO:0016458 41 27 0,000 0,07015826 0,08803273 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,07266199 0,09112463 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,07266199 0,09107497 ! phenol metabolic process GO:0018958 44 28 0,000 0,07266199 0,09102537 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,07266199 0,09097582 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,07266199 0,09092632 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,07266199 0,09087687 ! cell junction assembly GO:0034329 56 28 0,000 0,07266199 0,09082748 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,07266199 0,09077815 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,07266199 0,09072887 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,07266199 0,09067964 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,07266199 0,09063046 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,07266199 0,09058134 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,07266199 0,09053227 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,07266199 0,09048326 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,07266199 0,09043429 ! mesoderm formation GO:0001707 46 28 0,000 0,07266199 0,09038538 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,07266199 0,09033653 ! ensheathment of neurons GO:0007272 43 28 0,000 0,07266199 0,09028772 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,07266199 0,09023897 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,07266199 0,09019027 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,07266199 0,09014162 ! neural tube formation GO:0001841 41 28 0,000 0,07266199 0,09009303 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,07515912 0,09313899 ! regulation of innate immune response GO:0045088 38 29 0,000 0,07515912 0,09308884 ! ovulation cycle process GO:0022602 41 29 0,000 0,07515912 0,09303873 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,07515912 0,09298869 ! protein targeting to membrane GO:0006612 53 29 0,000 0,07515912 0,09293869 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,07515912 0,09288875 ! mismatch repair GO:0006298 34 29 0,000 0,07515912 0,09283887 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,07515912 0,09278903 ! muscle cell development GO:0055001 38 29 0,000 0,07515912 0,09273925 ! formation of primary germ layer GO:0001704 48 29 0,000 0,07515912 0,09268953 ! telencephalon development GO:0021537 52 29 0,000 0,07515912 0,09263985 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,07515912 0,09259023 ! eye morphogenesis GO:0048592 51 29 0,000 0,07515912 0,09254067 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,07515912 0,09249115 ! tissue homeostasis GO:0001894 42 29 0,000 0,07515912 0,09244169 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,07764966 0,09545389 ! collagen metabolic process GO:0032963 40 30 0,000 0,07764966 0,0954029 ! organic anion transport GO:0015711 51 30 0,000 0,07764966 0,09535196 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,07764966 0,09530108 ! spliceosome assembly GO:0000245 49 30 0,000 0,07764966 0,09525025 ! spindle organization GO:0007051 37 30 0,000 0,07764966 0,09519948 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,07764966 0,09514876 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,07764966 0,0950981 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,07764966 0,09504749 ! ceramide metabolic process GO:0006672 43 30 0,000 0,07764966 0,09499693 ! ovulation cycle GO:0042698 43 30 0,000 0,07764966 0,09494643 ! hindbrain development GO:0030902 45 30 0,000 0,07764966 0,09489598 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,07764966 0,09484558 ! adult locomotory behavior GO:0008344 47 30 0,000 0,07764966 0,09479524 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,07764966 0,09474495 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,07764966 0,09469471 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,07764966 0,09464453 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,07764966 0,0945944 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,08013365 0,09756876 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,08013365 0,09751714 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,08013365 0,09746557 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,08013365 0,09741405 ! odontogenesis GO:0042476 50 31 0,000 0,08013365 0,09736259 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,08013365 0,09731119 ! segmentation GO:0035282 41 31 0,000 0,08013365 0,09725984 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,08013365 0,09720854 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,08013365 0,09715729 ! metanephros development GO:0001656 58 31 0,000 0,08013365 0,09710611 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,08013365 0,09705497 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,08013365 0,09700389 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,08013365 0,09695286 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,08013365 0,09690189 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,08013365 0,09685097 ! RNA modification GO:0009451 40 31 0,000 0,08013365 0,0968001 ! regulation of muscle development GO:0048634 48 32 0,000 0,08261108 0,09974041 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,08261108 0,09968808 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,08261108 0,09963581 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,08261108 0,09958359 ! meiosis I GO:0007127 52 32 0,000 0,08261108 0,09953142 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,08261108 0,09947931 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,08261108 0,09942726 ! peripheral nervous system development GO:0007422 53 32 0,000 0,08261108 0,09937526 ! regulation of protein stability GO:0031647 48 32 0,000 0,08261108 0,09932331 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,08261108 0,09927141 ! cytokine production GO:0001816 44 32 0,000 0,08261108 0,09921958 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,08261108 0,09916779 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,08261108 0,09911606 ! vesicle localization GO:0051648 47 32 0,000 0,08261108 0,09906438 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,08508199 0,10197424 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,08508199 0,10192113 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,08508199 0,10186807 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,08508199 0,10181507 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,08508199 0,10176213 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,08508199 0,10170923 ! sister chromatid segregation GO:0000819 46 33 0,000 0,08508199 0,1016564 ! ear morphogenesis GO:0042471 42 33 0,000 0,08508199 0,10160362 ! actomyosin structure organization GO:0031032 43 33 0,000 0,08508199 0,10155089 ! cell junction organization GO:0034330 63 33 0,000 0,08508199 0,10149822 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,08508199 0,1014456 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,08508199 0,10139304 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,08508199 0,10134053 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,08508199 0,10128808 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,08508199 0,10123568 ! female gonad development GO:0008585 49 33 0,000 0,08508199 0,10118333 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,08508199 0,10113104 ! positive regulation of cell development GO:0010720 54 33 0,000 0,08508199 0,10107881 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,08508199 0,10102662 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,08508199 0,10097449 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,08508199 0,10092242 ! cytokinesis GO:0000910 52 33 0,000 0,08508199 0,1008704 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,08508199 0,10081843 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,08754638 0,1036852 ! mRNA catabolic process GO:0006402 48 34 0,000 0,08754638 0,10363184 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,08754638 0,10357853 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,08754638 0,10352528 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,08754638 0,10347208 ! feeding behavior GO:0007631 45 34 0,000 0,08754638 0,10341893 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,08754638 0,10336584 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,08754638 0,10331281 ! neuron migration GO:0001764 46 34 0,000 0,08754638 0,10325983 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,08754638 0,1032069 ! female gamete generation GO:0007292 43 34 0,000 0,08754638 0,10315403 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,08754638 0,10310121 ! polyol metabolic process GO:0019751 44 34 0,000 0,08754638 0,10304845 ! aerobic respiration GO:0009060 47 34 0,000 0,08754638 0,10299574 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,08754638 0,10294308 ! embryonic organ development GO:0048568 45 34 0,000 0,08754638 0,10289048 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,08754638 0,10283793 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,09000427 0,10567117 ! Notch signaling pathway GO:0007219 56 35 0,000 0,09000427 0,10561725 ! regulation of intracellular protein transport GO:0033157 59 35 0,000 0,09000427 0,1055634 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,09000427 0,10550959 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,09000427 0,10545584 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,09000427 0,10540215 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,09000427 0,10534851 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,09000427 0,10529492 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,09000427 0,10524139 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,09000427 0,10518792 ! pigment metabolic process GO:0042440 61 35 0,000 0,09000427 0,10513449 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,09245568 0,10794318 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,09245568 0,10788842 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,09245568 0,10783371 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,09245568 0,10777905 ! negative regulation of binding GO:0051100 58 36 0,000 0,09245568 0,10772445 ! neural tube development GO:0021915 50 36 0,000 0,09245568 0,10766991 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,09245568 0,10761542 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,09245568 0,10756099 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,09245568 0,10750661 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,09245568 0,10745228 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,09490063 0,11023811 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,09490063 0,11018246 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,09490063 0,11012687 ! learning GO:0007612 67 37 0,000 0,09490063 0,11007133 ! ion transmembrane transport GO:0034220 56 37 0,000 0,09490063 0,11001585 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,09490063 0,10996043 ! amino acid activation GO:0043038 52 37 0,000 0,09490063 0,10990506 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,09490063 0,10984975 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,09733913 0,1126157 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,09733913 0,11255908 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,09733913 0,11250252 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,09733913 0,11244601 ! phagocytosis GO:0006909 60 38 0,000 0,09733913 0,11238956 ! mesenchymal cell development GO:0014031 64 38 0,000 0,09733913 0,11233317 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,09733913 0,11227683 ! maintenance of location in cell GO:0051651 69 38 0,000 0,09733913 0,11222056 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,09977121 0,11496682 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,09977121 0,11490925 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,09977121 0,11485174 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,09977121 0,11479428 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,09977121 0,11473689 ! male sex differentiation GO:0046661 53 39 0,000 0,09977121 0,11467955 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,09977121 0,11462226 ! chromatin remodeling GO:0006338 68 39 0,000 0,09977121 0,11456504 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,09977121 0,11450787 ! JNK cascade GO:0007254 54 39 0,000 0,09977121 0,11445076 ! synapse organization GO:0050808 55 39 0,000 0,09977121 0,11439371 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,10219686 0,11711649 ! response to calcium ion GO:0051592 58 40 0,000 0,10219686 0,11705816 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,10219686 0,11699989 ! regulation of tube size GO:0035150 60 40 0,000 0,10219686 0,11694168 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,10219686 0,11688353 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,10219686 0,11682544 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,10219686 0,1167674 ! inner ear development GO:0048839 57 40 0,000 0,10219686 0,11670943 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,10219686 0,11665151 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,10219686 0,11659364 ! double-strand break repair GO:0006302 67 40 0,000 0,10219686 0,11653584 ! B cell differentiation GO:0030183 62 40 0,000 0,10219686 0,11647809 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,10219686 0,1164204 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,10219686 0,11636277 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,10219686 0,11630519 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,10461612 0,11899955 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,10461612 0,11894072 ! endosome transport GO:0016197 71 41 0,000 0,10461612 0,11888196 ! striated muscle contraction GO:0006941 62 41 0,000 0,10461612 0,11882325 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,10461612 0,1187646 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,10461612 0,11870601 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,10461612 0,11864748 ! biopolymer methylation GO:0043414 62 41 0,000 0,10461612 0,118589 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,10461612 0,11853058 ! mitochondrial transport GO:0006839 60 42 0,000 0,107029 0,12120468 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,107029 0,12114503 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 0,000 0,107029 0,12108545 ! cellular component disassembly GO:0022411 64 42 0,000 0,107029 0,12102591 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,107029 0,12096644 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,107029 0,12090703 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,107029 0,12084767 ! excretion GO:0007588 63 42 0,000 0,107029 0,12078838 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,107029 0,12072914 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,107029 0,12066996 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,107029 0,12061083 ! regulation of cell shape GO:0008360 78 42 0,000 0,107029 0,12055177 ! positive regulation of binding GO:0051099 59 43 0,000 0,10943552 0,12320201 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,10943552 0,12314173 ! leukocyte migration GO:0050900 60 43 0,000 0,10943552 0,12308151 ! neuromuscular process GO:0050905 79 43 0,000 0,10943552 0,12302136 ! activation of caspase activity GO:0006919 65 43 0,000 0,10943552 0,12296126 ! tRNA processing GO:0008033 49 43 0,000 0,10943552 0,12290122 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,10943552 0,12284124 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,10943552 0,12278132 ! methylation GO:0032259 64 43 0,000 0,10943552 0,12272145 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,11183569 0,12535189 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,11183569 0,12529083 ! regulation of action potential GO:0001508 71 44 0,000 0,11183569 0,12522984 ! regulation of ion transport GO:0043269 57 44 0,000 0,11183569 0,1251689 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,11183569 0,12510802 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,11183569 0,1250472 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,11183569 0,12498643 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,11183569 0,12492573 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,11183569 0,12486509 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,11183569 0,1248045 ! RNA catabolic process GO:0006401 64 45 0,000 0,11422952 0,12741412 ! positive regulation of defense response GO:0031349 59 45 0,000 0,11422952 0,12735235 ! regulation of translational initiation GO:0006446 64 45 0,000 0,11422952 0,12729065 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,11422952 0,12722901 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,11422952 0,12716743 ! cell recognition GO:0008037 58 45 0,000 0,11422952 0,12710591 ! cell maturation GO:0048469 60 45 0,000 0,11422952 0,12704444 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,11661705 0,12963712 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,11661705 0,1295745 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,11661705 0,12951193 ! histone modification GO:0016570 68 46 0,000 0,11661705 0,12944942 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,11661705 0,12938698 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,11899827 0,13196529 ! viral infectious cycle GO:0019058 71 47 0,000 0,11899827 0,1319017 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,11899827 0,13183816 ! endocrine system development GO:0035270 83 47 0,000 0,11899827 0,13177468 ! covalent chromatin modification GO:0016569 75 47 0,000 0,11899827 0,13171127 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,11899827 0,13164792 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,11899827 0,13158462 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,11899827 0,13152139 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,11899827 0,13145822 ! chloride transport GO:0006821 67 48 0,000 0,12137321 0,13401747 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,12137321 0,13395316 GO:0010952|positive regulation of peptidase activity, ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,12137321 0,13388891 ! gastrulation GO:0007369 73 48 0,000 0,12137321 0,13382473 ! heart morphogenesis GO:0003007 65 48 0,000 0,12137321 0,1337606 ! regulation of DNA replication GO:0006275 75 48 0,000 0,12137321 0,13369654 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,12137321 0,13363254 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,12137321 0,1335686 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,12137321 0,13350473 ! regulation of endocytosis GO:0030100 63 48 0,000 0,12137321 0,13344091 ! nuclear export GO:0051168 69 48 0,000 0,12137321 0,13337715 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,12137321 0,13331346 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,12137321 0,13324982 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,12374188 0,13578546 ! sensory perception of smell GO:0007608 61 49 0,000 0,12374188 0,13572071 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,12374188 0,13565602 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,12374188 0,13559139 ! RNA elongation GO:0006354 62 49 0,000 0,12374188 0,13552682 ! regulation of intracellular transport GO:0032386 78 49 0,000 0,12374188 0,13546232 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,12374188 0,13539787 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,12374188 0,13533349 ! cartilage development GO:0051216 70 49 0,000 0,12374188 0,13526917 ! maintenance of location GO:0051235 84 49 0,000 0,12374188 0,13520491 ! regulation of actin filament length GO:0030832 72 50 0,000 0,12610431 0,13772075 ! ear development GO:0043583 72 50 0,000 0,12610431 0,13765539 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,12610431 0,13759009 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,12610431 0,13752485 ! proton transport GO:0015992 75 50 0,000 0,12610431 0,13745967 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,12610431 0,13739455 ! positive regulation of secretion GO:0051047 71 51 0,000 0,1284605 0,13989543 ! hydrogen transport GO:0006818 77 51 0,000 0,1284605 0,13982922 ! muscle fiber development GO:0048747 74 51 0,000 0,1284605 0,13976308 ! adult behavior GO:0030534 80 51 0,000 0,1284605 0,13969699 ! transition metal ion transport GO:0000041 74 52 0,000 0,13081047 0,14218529 ! regulation of cellular component size GO:0032535 74 52 0,000 0,13081047 0,14211813 ! aging GO:0007568 79 52 0,000 0,13081047 0,14205103 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,13081047 0,14198399 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,13081047 0,14191702 ! establishment of organelle localization GO:0051656 85 52 0,000 0,13081047 0,14185011 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,13315424 0,14432363 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,13315424 0,14425565 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,13315424 0,14418773 ! kidney development GO:0001822 90 53 0,000 0,13315424 0,14411988 ! single fertilization GO:0007338 59 53 0,000 0,13315424 0,14405209 ! cell projection assembly GO:0030031 76 53 0,000 0,13315424 0,14398437 ! amino acid transport GO:0006865 84 54 0,000 0,13549182 0,14644323 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,13549182 0,14637444 ! DNA catabolic process GO:0006308 67 54 0,000 0,13549182 0,14630572 ! detection of external stimulus GO:0009581 66 54 0,000 0,13549182 0,14623707 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,13549182 0,14616848 ! exocytosis GO:0006887 74 55 0,000 0,13782324 0,1486139 ! mesoderm development GO:0007498 76 55 0,000 0,13782324 0,14854426 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,13782324 0,14847468 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,13782324 0,14840517 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,1401485 0,15083834 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,1401485 0,15076779 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,14246762 0,15319099 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,14246762 0,1531194 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,14246762 0,15304788 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,14246762 0,15297643 ! camera-type eye development GO:0043010 88 57 0,000 0,14246762 0,15290505 ! secondary metabolic process GO:0019748 84 57 0,000 0,14246762 0,15283373 ! gonad development GO:0008406 79 57 0,000 0,14246762 0,15276248 ! viral reproductive process GO:0022415 87 58 0,000 0,14478062 0,15517028 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,14478062 0,15509801 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,14478062 0,1550258 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,14708751 0,15742265 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,14708751 0,15734943 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,14938831 0,15973646 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,14938831 0,15966223 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,14938831 0,15958807 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,14938831 0,15951398 ! regulation of heart contraction GO:0008016 91 60 0,000 0,14938831 0,15943996 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,14938831 0,15936601 ! fertilization GO:0009566 68 60 0,000 0,14938831 0,15929213 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,15168304 0,16166404 ! meiosis GO:0007126 96 61 0,000 0,15168304 0,16158916 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,15168304 0,16151435 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,15168304 0,16143961 ! urogenital system development GO:0001655 101 61 0,000 0,15168304 0,16136494 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,15168304 0,16129034 ! extracellular matrix organization GO:0030198 103 61 0,000 0,15168304 0,1612158 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,15168304 0,16114134 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,15168304 0,16106694 ! amine catabolic process GO:0009310 90 62 0,000 0,15397171 0,16342175 ! neurotransmitter transport GO:0006836 81 62 0,000 0,15397171 0,16334637 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,15397171 0,16327106 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,15397171 0,16319582 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,15397171 0,16312065 ! meiotic cell cycle GO:0051321 97 62 0,000 0,15397171 0,16304555 ! organelle localization GO:0051640 96 62 0,000 0,15397171 0,16297052 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,15625434 0,16531047 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,15625434 0,16523447 ! viral reproduction GO:0016032 92 63 0,000 0,15625434 0,16515854 ! appendage morphogenesis GO:0035107 93 64 0,000 0,15853093 0,16748789 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,15853093 0,16741099 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,15853093 0,16733417 ! adaptive immune response GO:0002250 94 64 0,000 0,15853093 0,16725741 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,16080152 0,16957519 ! regulation of caspase activity GO:0043281 97 65 0,000 0,16080152 0,16949748 ! appendage development GO:0048736 94 65 0,000 0,16080152 0,16941983 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,16080152 0,16934226 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,16080152 0,16926476 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,16080152 0,16918732 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,16080152 0,16910996 ! activation of immune response GO:0002253 83 65 0,000 0,16080152 0,16903267 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,16306611 0,17133488 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,16306611 0,17125664 ! antigen processing and presentation GO:0019882 96 66 0,000 0,16306611 0,17117848 ! axon guidance GO:0007411 99 66 0,000 0,16306611 0,17110038 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,16306611 0,17102236 ! regulation of immune effector process GO:0002697 101 66 0,000 0,16306611 0,17094441 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,16532471 0,17323318 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,16532471 0,1731543 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,16532471 0,17307548 ! acute inflammatory response GO:0002526 92 68 0,000 0,16757735 0,17535392 ! learning or memory GO:0007611 123 68 0,000 0,16757735 0,17527418 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,16757735 0,17519451 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,16757735 0,17511491 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,16757735 0,17503538 ! rhythmic process GO:0048511 105 68 0,000 0,16757735 0,17495593 ! inorganic anion transport GO:0015698 93 68 0,000 0,16757735 0,17487655 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,16982404 0,17714073 ! response to drug GO:0042493 108 69 0,000 0,16982404 0,17706043 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,16982404 0,1769802 ! response to metal ion GO:0010038 103 70 0,000 0,1720648 0,17923417 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,1720648 0,17915303 ! humoral immune response GO:0006959 86 70 0,000 0,1720648 0,17907196 ! eye development GO:0001654 111 70 0,000 0,1720648 0,17899097 ! amine transport GO:0015837 101 70 0,000 0,1720648 0,17891005 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,17429963 0,1811519 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,17429963 0,18107008 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,17429963 0,18098833 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,17429963 0,18090666 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,17652856 0,18313744 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,17652856 0,18305487 ! regulation of blood pressure GO:0008217 107 73 0,000 0,17875161 0,18527656 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,17875161 0,18519311 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,17875161 0,18510972 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,18096877 0,18732141 ! digestion GO:0007586 97 74 0,000 0,18096877 0,18723715 ! blood coagulation GO:0007596 116 75 0,000 0,18318008 0,18943983 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,18318008 0,18935469 ! regulation of ligase activity GO:0051340 114 75 0,000 0,18318008 0,18926963 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,18318008 0,18918464 ! amine biosynthetic process GO:0009309 97 76 0,000 0,18538555 0,19137646 ! tRNA metabolic process GO:0006399 95 76 0,000 0,18538555 0,19129061 ! response to unfolded protein GO:0006986 99 76 0,000 0,18538555 0,19120483 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,18538555 0,19111912 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,18758519 0,19330015 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,18758519 0,19321358 ! regulation of DNA binding GO:0051101 119 77 0,000 0,18758519 0,19312709 ! sex differentiation GO:0007548 105 77 0,000 0,18758519 0,19304068 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,18758519 0,19295435 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,18758519 0,19286809 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,18977901 0,19503652 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,18977901 0,19494941 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,19196703 0,19710901 ! cellular respiration GO:0045333 107 79 0,000 0,19196703 0,19702105 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,19196703 0,19693318 ! T cell activation GO:0042110 134 79 0,000 0,19196703 0,19684538 ! regulation of lyase activity GO:0051339 133 79 0,000 0,19196703 0,19675766 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,19196703 0,19667001 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,19414928 0,19881716 GO:0010498|proteasomal protein catabolic process, ! forebrain development GO:0030900 131 80 0,000 0,19414928 0,19872868 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,19632575 0,20086709 ! hemostasis GO:0007599 125 81 0,000 0,19632575 0,20077778 ! mRNA transport GO:0051028 121 81 0,000 0,19632575 0,20068854 ! response to protein stimulus GO:0051789 111 81 0,000 0,19632575 0,20059939 ! regulation of neurological system process GO:0031644 122 81 0,000 0,19632575 0,20051031 ! vitamin metabolic process GO:0006766 103 81 0,000 0,19632575 0,20042131 ! detection of stimulus GO:0051606 108 82 0,000 0,19849647 0,20254742 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,20066145 0,20466578 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,20066145 0,20457506 ! regulation of defense response GO:0031347 117 84 0,000 0,20282071 0,20668481 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,20282071 0,20659328 ! sterol metabolic process GO:0016125 120 84 0,000 0,20282071 0,20650183 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,20497425 0,20860212 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,20497425 0,20850986 ! rRNA metabolic process GO:0016072 107 85 0,000 0,20497425 0,20841768 GO:0006364|rRNA processing, ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,20497425 0,20832558 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,20712211 0,21041557 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,20926428 0,21249795 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,20926428 0,21240417 ! female pregnancy GO:0007565 130 87 0,000 0,20926428 0,21231048 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,21140079 0,21438352 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,21140079 0,21428903 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,21140079 0,21419463 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,21140079 0,21410032 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,21140079 0,21400608 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,21353165 0,2160681 ! reproductive developmental process GO:0003006 127 89 0,000 0,21353165 0,21597308 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,21353165 0,21587815 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,21353165 0,2157833 ! regulation of T cell activation GO:0050863 128 89 0,000 0,21353165 0,21568854 ! leukocyte differentiation GO:0002521 143 90 0,000 0,21565687 0,2177396 ! hormone metabolic process GO:0042445 121 90 0,000 0,21565687 0,21764406 ! RNA localization GO:0006403 135 91 0,000 0,21777648 0,2196868 ! ATP metabolic process GO:0046034 137 91 0,000 0,21777648 0,21959048 ! response to virus GO:0009615 122 91 0,000 0,21777648 0,21949426 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,21989047 0,22152785 ! positive regulation of immune response GO:0050778 121 92 0,000 0,21989047 0,22143086 ! DNA recombination GO:0006310 146 92 0,000 0,21989047 0,22133395 ! electron transport chain GO:0022900 123 94 0,000 0,2241017 0,22547415 ! response to oxidative stress GO:0006979 141 94 0,000 0,2241017 0,22537556 ! regulation of binding GO:0051098 151 95 0,000 0,22619897 0,22738532 ! carboxylic acid transport GO:0046942 147 95 0,000 0,22619897 0,22728599 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,22829068 0,22928758 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,22829068 0,2291875 ! protein maturation GO:0051604 129 96 0,000 0,22829068 0,22908751 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,23037686 0,23108015 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,23037686 0,23097942 ! extracellular structure organization GO:0043062 156 99 0,000 0,23453268 0,23504364 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,23453268 0,23494127 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,23660234 0,23691136 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,23660234 0,23680826 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,23660234 0,23670526 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,23660234 0,23660234