pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/639-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 5,454E-07 1,254E-03 ! interphase GO:0051325 159 88 4,000 6,119E-07 7,037E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 1,233E-06 9,449E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 2,469E-06 1,42E-03 ! G1 phase GO:0051318 27 16 2,000 3,375E-06 1,552E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 3,872E-06 1,484E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 4,093E-06 1,345E-03 ! negative regulation of kinase activity GO:0033673 100 58 3,000 4,154E-06 1,194E-03 ! negative regulation of transferase activity GO:0051348 105 61 3,000 5,089E-06 1,3E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 5,817E-06 1,338E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 5,817E-06 1,216E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 6,835E-06 1,31E-03 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 9,209E-06 1,629E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 2,000 1,207E-05 1,983E-03 ! membrane docking GO:0022406 39 27 2,000 1,738E-05 2,665E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 3,443E-05 4,95E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 3,443E-05 4,658E-03 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 3,443E-05 4,4E-03 ! lymphocyte activation during immune response GO:0002285 9 5 1,000 3,443E-05 4,168E-03 ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 3,443E-05 3,96E-03 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 3,849E-05 4,216E-03 ! protein homooligomerization GO:0051260 52 35 2,000 3,849E-05 4,024E-03 ! virion attachment to host cell surface receptor GO:0019062 11 6 1,000 5,159E-05 5,159E-03 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 5,159E-05 4,944E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 5,159E-05 4,746E-03 ! ER overload response GO:0006983 7 6 1,000 5,159E-05 4,563E-03 ! T cell mediated immunity GO:0002456 12 6 1,000 5,159E-05 4,394E-03 ! interaction with symbiont GO:0051702 8 6 1,000 5,159E-05 4,238E-03 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 5,159E-05 4,091E-03 ! gas homeostasis GO:0033483 11 6 1,000 5,159E-05 3,955E-03 ! membrane to membrane docking GO:0022614 12 6 1,000 5,159E-05 3,827E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 5,159E-05 3,708E-03 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 5,159E-05 3,595E-03 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 5,347E-05 3,617E-03 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 5,773E-05 3,794E-03 ! positive regulation of protein transport GO:0051222 55 40 2,000 5,773E-05 3,688E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 6,691E-05 4,159E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 7,214E-05 4,366E-03 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 7,214E-05 4,254E-03 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 7,214E-05 4,148E-03 ! vesicle fusion GO:0006906 15 7 1,000 7,214E-05 4,047E-03 ! response to UV GO:0009411 75 46 2,000 8,802E-05 4,82E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 9,607E-05 5,139E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 9,607E-05 5,022E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 9,607E-05 4,91E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 9,607E-05 4,803E-03 ! induction of an organ GO:0001759 11 8 1,000 9,607E-05 4,701E-03 ! leukocyte activation during immune response GO:0002366 13 8 1,000 9,607E-05 4,603E-03 GO:0002263|cell activation during immune response, ! regulation of macrophage differentiation GO:0045649 14 8 1,000 9,607E-05 4,509E-03 ! regulation of intracellular transport GO:0032386 78 49 2,000 1,064E-04 4,895E-03 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,2E-04 5,411E-03 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 1,234E-04 5,457E-03 ! oocyte differentiation GO:0009994 12 9 1,000 1,234E-04 5,354E-03 GO:0048599|oocyte development, ! positive regulation of protein polymerization GO:0032273 15 9 1,000 1,234E-04 5,255E-03 ! localization within membrane GO:0051668 15 9 1,000 1,234E-04 5,159E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 1,54E-04 6,326E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,54E-04 6,215E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,54E-04 6,108E-03 ! entry into host cell GO:0030260 20 10 1,000 1,54E-04 6,005E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,54E-04 5,905E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,54E-04 5,808E-03 ! developmental induction GO:0031128 13 10 1,000 1,54E-04 5,714E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of lipid metabolic process GO:0019216 84 56 2,000 1,587E-04 5,793E-03 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,587E-04 5,702E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,88E-04 6,654E-03 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,88E-04 6,553E-03 ! negative regulation of cell growth GO:0030308 106 62 2,000 2,148E-04 7,375E-03 ! histone acetylation GO:0016573 23 12 1,000 2,254E-04 7,623E-03 ! gland morphogenesis GO:0022612 23 12 1,000 2,254E-04 7,513E-03 ! peptidyl-lysine modification GO:0018205 18 12 1,000 2,254E-04 7,405E-03 ! negative regulation of cell size GO:0045792 108 64 2,000 2,361E-04 7,647E-03 ! protein oligomerization GO:0051259 100 65 2,000 2,472E-04 7,895E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,66E-04 8,382E-03 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 2,66E-04 8,269E-03 ! lipid localization GO:0010876 24 13 1,000 2,66E-04 8,159E-03 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 2,66E-04 8,051E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 2,66E-04 7,947E-03 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 2,66E-04 7,845E-03 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 3,1E-04 9,026E-03 ! heterophilic cell adhesion GO:0007157 29 14 1,000 3,1E-04 8,913E-03 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 3,1E-04 8,803E-03 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 3,1E-04 8,696E-03 ! regulation of peptidase activity GO:0052547 106 72 2,000 3,344E-04 9,268E-03 ! response to hypoxia GO:0001666 132 72 2,000 3,344E-04 9,157E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 3,573E-04 9,668E-03 ! regulation of vasodilation GO:0042312 24 15 1,000 3,573E-04 9,555E-03 ! response to oxygen levels GO:0070482 137 74 2,000 3,626E-04 9,585E-03 ! negative regulation of growth GO:0045926 123 75 2,000 3,772E-04 9,859E-03 ! regulation of protein transport GO:0051223 114 76 2,000 3,922E-04 0,01013546 GO:0070201|regulation of establishment of protein localization, ! protein amino acid acetylation GO:0006473 28 16 1,000 4,078E-04 0,01042282 ! oogenesis GO:0048477 23 16 1,000 4,078E-04 0,01030828 ! inactivation of MAPK activity GO:0000188 27 17 1,000 4,617E-04 0,01154209 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 4,617E-04 0,01141798 ! peptidyl-serine modification GO:0018209 27 17 1,000 4,617E-04 0,01129652 ! regulation of cell adhesion GO:0030155 159 83 2,000 5,08E-04 0,0122992 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 5,188E-04 0,01242913 ! regulation of protein localization GO:0032880 132 85 2,000 5,447E-04 0,01291555 ! cell cycle arrest GO:0007050 150 86 2,000 5,637E-04 0,01322883 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 5,791E-04 0,01345453 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 5,791E-04 0,01331998 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 5,791E-04 0,0131881 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 5,791E-04 0,01305881 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 5,791E-04 0,01293202 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 6,427E-04 0,01421396 ! positive regulation of B cell activation GO:0050871 31 20 1,000 6,427E-04 0,01407859 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 1,000 6,427E-04 0,01394577 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 7,083E-04 0,01522571 ! regulation of cell killing GO:0031341 34 21 1,000 7,095E-04 0,01511045 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 7,095E-04 0,01497183 ! protein amino acid acylation GO:0043543 37 21 1,000 7,095E-04 0,01483572 ! vesicle docking GO:0048278 27 21 1,000 7,095E-04 0,01470206 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 7,095E-04 0,01457079 ! regulation of vasoconstriction GO:0019229 31 21 1,000 7,095E-04 0,01444185 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 7,095E-04 0,01431517 ! response to light stimulus GO:0009416 153 96 2,000 7,769E-04 0,01553826 ! leukocyte adhesion GO:0007159 38 22 1,000 7,796E-04 0,01545693 ! vasculogenesis GO:0001570 33 22 1,000 7,796E-04 0,01532482 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 7,796E-04 0,01519495 GO:0010810|regulation of cell-substrate adhesion, ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 7,796E-04 0,01506726 ! membrane depolarization GO:0051899 35 22 1,000 7,796E-04 0,0149417 ! regulation of blood coagulation GO:0030193 34 22 1,000 7,796E-04 0,01481821 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 8,528E-04 0,01607745 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 8,528E-04 0,01594674 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 8,528E-04 0,01581814 ! vesicle targeting GO:0006903 32 23 1,000 8,528E-04 0,01569159 ! interaction with host GO:0051701 37 23 1,000 8,528E-04 0,01556706 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 8,528E-04 0,01544448 ! initiation of viral infection GO:0019059 42 24 1,000 9,292E-04 0,01669718 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 9,292E-04 0,01656774 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 9,292E-04 0,0164403 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 9,292E-04 0,0163148 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 1,009E-03 0,01757837 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 1,009E-03 0,0174462 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,092E-03 0,01873688 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 1,092E-03 0,01859809 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 1,092E-03 0,01846134 ! regulation of coagulation GO:0050818 39 26 1,000 1,092E-03 0,01832659 ! cholesterol homeostasis GO:0042632 46 28 1,000 1,267E-03 0,0211109 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 1,000 1,267E-03 0,02095902 ! erythrocyte differentiation GO:0030218 38 28 1,000 1,267E-03 0,02080931 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 1,267E-03 0,02066173 ! regulation of B cell activation GO:0050864 42 28 1,000 1,267E-03 0,02051622 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 1,359E-03 0,02185605 ! cholesterol transport GO:0030301 46 30 1,000 1,454E-03 0,02322716 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 1,000 1,454E-03 0,02306697 ! establishment of vesicle localization GO:0051650 45 30 1,000 1,454E-03 0,02290898 ! mammary gland development GO:0030879 57 31 1,000 1,553E-03 0,02429364 ! cell fate specification GO:0001708 37 31 1,000 1,553E-03 0,0241295 ! neutral lipid metabolic process GO:0006638 41 32 1,000 1,654E-03 0,02553526 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 1,000 1,654E-03 0,02536502 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 1,654E-03 0,02519704 ! vesicle localization GO:0051648 47 32 1,000 1,654E-03 0,02503127 ! lipid homeostasis GO:0055088 55 33 1,000 1,759E-03 0,02644084 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 1,759E-03 0,02626914 ! glycerol ether metabolic process GO:0006662 44 34 1,000 1,867E-03 0,02769822 ! erythrocyte homeostasis GO:0034101 45 34 1,000 1,867E-03 0,02752066 ! female gamete generation GO:0007292 43 34 1,000 1,867E-03 0,02734537 ! glycogen metabolic process GO:0005977 48 35 1,000 1,977E-03 0,02878515 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 1,977E-03 0,02860411 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! organic ether metabolic process GO:0018904 46 36 1,000 2,091E-03 0,03006195 ! tissue remodeling GO:0048771 62 36 1,000 2,091E-03 0,02987523 ! glucan metabolic process GO:0044042 49 36 1,000 2,091E-03 0,02969082 GO:0006073|cellular glucan metabolic process, ! gliogenesis GO:0042063 71 38 1,000 2,328E-03 0,03285039 ! striated muscle cell differentiation GO:0051146 54 38 1,000 2,328E-03 0,03265009 ! cell growth GO:0016049 61 39 1,000 2,451E-03 0,03416609 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 2,577E-03 0,03570556 ! energy reserve metabolic process GO:0006112 59 41 1,000 2,706E-03 0,0372679 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 2,838E-03 0,03885258 ! leukocyte migration GO:0050900 60 43 1,000 2,973E-03 0,04045902 ! vesicle organization GO:0016050 79 43 1,000 2,973E-03 0,04022103 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 3,111E-03 0,0418406 ! positive regulation of cell cycle GO:0045787 77 45 1,000 3,252E-03 0,04348086 ! cell maturation GO:0048469 60 45 1,000 3,252E-03 0,04322952 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 3,252E-03 0,04298108 ! regulation of ossification GO:0030278 71 46 1,000 3,395E-03 0,04462541 ! histone modification GO:0016570 68 46 1,000 3,395E-03 0,04437186 ! viral infectious cycle GO:0019058 71 47 1,000 3,542E-03 0,04602788 ! covalent chromatin modification GO:0016569 75 47 1,000 3,542E-03 0,0457693 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 3,542E-03 0,0455136 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 1,000 3,542E-03 0,04526075 ! regulation of muscle contraction GO:0006937 69 48 1,000 3,692E-03 0,04691241 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 3,692E-03 0,04665465 ! germ cell development GO:0007281 68 49 1,000 3,844E-03 0,04831725 ! membrane fusion GO:0006944 80 50 1,000 4E-03 0,04999805 ! activation of phospholipase C activity GO:0007202 87 51 1,000 4,158E-03 0,05169662 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of organelle organization GO:0010638 82 51 1,000 4,158E-03 0,05141868 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 4,319E-03 0,0531269 ! establishment of organelle localization GO:0051656 85 52 1,000 4,319E-03 0,05284431 ! regulation of bone remodeling GO:0046850 90 53 1,000 4,484E-03 0,05456183 ! regulation of protein complex assembly GO:0043254 81 54 1,000 4,651E-03 0,05629588 ! regulation of phospholipase activity GO:0010517 90 54 1,000 4,651E-03 0,05600114 ! regulation of tissue remodeling GO:0034103 91 54 1,000 4,651E-03 0,05570946 ! positive regulation of lipase activity GO:0060193 90 54 1,000 4,651E-03 0,05542081 ! developmental maturation GO:0021700 75 57 1,000 5,168E-03 0,06127582 ! viral reproductive process GO:0022415 87 58 1,000 5,347E-03 0,06306457 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 5,347E-03 0,06274281 ! lung development GO:0030324 94 59 1,000 5,528E-03 0,06453871 ! myeloid cell differentiation GO:0030099 85 59 1,000 5,528E-03 0,06421276 ! regulation of homeostatic process GO:0032844 105 60 1,000 5,712E-03 0,06601552 ! meiosis GO:0007126 96 61 1,000 5,898E-03 0,06783228 GO:0051327|M phase of meiotic cell cycle, ! homeostasis of number of cells GO:0048872 84 61 1,000 5,898E-03 0,0674948 ! respiratory tube development GO:0030323 99 62 1,000 6,088E-03 0,06931782 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 6,088E-03 0,06897636 ! meiotic cell cycle GO:0051321 97 62 1,000 6,088E-03 0,06863824 ! organelle localization GO:0051640 96 62 1,000 6,088E-03 0,06830342 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 6,28E-03 0,07011797 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 6,28E-03 0,06977923 ! viral reproduction GO:0016032 92 63 1,000 6,28E-03 0,06944375 ! regulation of lipase activity GO:0060191 109 63 1,000 6,28E-03 0,06911149 ! cell cycle checkpoint GO:0000075 108 64 1,000 6,475E-03 0,07091777 ! respiratory system development GO:0060541 100 64 1,000 6,475E-03 0,07058167 ! adaptive immune response GO:0002250 94 64 1,000 6,475E-03 0,07024874 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of caspase activity GO:0043281 97 65 1,000 6,673E-03 0,07205386 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 6,673E-03 0,07171716 ! antigen processing and presentation GO:0019882 96 66 1,000 6,873E-03 0,07352788 ! regulation of immune effector process GO:0002697 101 66 1,000 6,873E-03 0,07318747 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 7,076E-03 0,07500357 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 7,702E-03 0,08126119 ! muscle cell differentiation GO:0042692 104 71 1,000 7,916E-03 0,08313708 ! leukocyte mediated immunity GO:0002443 99 71 1,000 7,916E-03 0,08275919 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 8,133E-03 0,08463911 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 8,574E-03 0,08882892 ! gland development GO:0048732 148 77 1,000 9,256E-03 0,09546034 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 9,404E-03 0,09655673 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 9,404E-03 0,09612759 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 9,404E-03 0,09570225 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 9,404E-03 0,09528065 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 9,404E-03 0,09486275 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,404E-03 0,09444851 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 9,404E-03 0,09403786 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 9,404E-03 0,09363077 ! sleep GO:0030431 11 5 0,000 9,404E-03 0,09322719 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,404E-03 0,09282707 ! nucleotide-sugar transport GO:0015780 8 5 0,000 9,404E-03 0,09243037 ! regulation of interferon-beta production GO:0032648 5 5 0,000 9,404E-03 0,09203705 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 9,404E-03 0,09164707 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 9,404E-03 0,09126037 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 9,404E-03 0,09087692 ! tongue development GO:0043586 6 5 0,000 9,404E-03 0,09049668 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 9,404E-03 0,09011962 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 9,404E-03 0,08974568 ! cobalt ion transport GO:0006824 9 5 0,000 9,404E-03 0,08937483 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 9,404E-03 0,08900703 ! SMAD protein complex assembly GO:0007183 9 5 0,000 9,404E-03 0,08864224 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 9,404E-03 0,08828044 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 9,404E-03 0,08792158 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 9,404E-03 0,08756562 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 9,404E-03 0,08721253 ! embryonic camera-type eye development GO:0031076 8 5 0,000 9,404E-03 0,08686228 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 9,404E-03 0,08651483 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 9,404E-03 0,08617015 ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,404E-03 0,08582821 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 9,404E-03 0,08548896 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 9,404E-03 0,08515239 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 9,404E-03 0,08481846 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 9,404E-03 0,08448714 ! positive regulation of histone modification GO:0031058 5 5 0,000 9,404E-03 0,0841584 ! malate metabolic process GO:0006108 7 5 0,000 9,404E-03 0,0838322 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 9,404E-03 0,08350852 ! behavioral response to pain GO:0048266 7 5 0,000 9,404E-03 0,08318734 ! clathrin coat assembly GO:0048268 11 5 0,000 9,404E-03 0,08286861 ! phototransduction, visible light GO:0007603 6 5 0,000 9,404E-03 0,08255232 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,404E-03 0,08223843 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 9,404E-03 0,08192692 ! mating behavior GO:0007617 6 5 0,000 9,404E-03 0,08161776 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 9,404E-03 0,08131093 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 9,404E-03 0,0810064 ! rhythmic behavior GO:0007622 12 5 0,000 9,404E-03 0,08070413 ! copulation GO:0007620 7 5 0,000 9,404E-03 0,08040412 ! glial cell fate commitment GO:0021781 12 5 0,000 9,404E-03 0,08010632 ! protein maturation by protein folding GO:0022417 12 5 0,000 9,404E-03 0,07981073 ! embryonic hemopoiesis GO:0035162 10 5 0,000 9,404E-03 0,07951731 ! regulation of potassium ion transport GO:0043266 9 5 0,000 9,404E-03 0,07922604 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 9,404E-03 0,07893689 ! apoptotic cell clearance GO:0043277 13 5 0,000 9,404E-03 0,07864985 ! lipoprotein particle clearance GO:0034381 9 5 0,000 9,404E-03 0,07836488 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 9,404E-03 0,07808198 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,404E-03 0,07780111 ! response to protozoan GO:0001562 9 5 0,000 9,404E-03 0,07752225 ! positive regulation of glycolysis GO:0045821 11 5 0,000 9,404E-03 0,07724538 ! lymph vessel development GO:0001945 7 5 0,000 9,404E-03 0,07697049 ! endochondral ossification GO:0001958 12 5 0,000 9,404E-03 0,07669754 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 9,404E-03 0,07642653 ! parathyroid gland development GO:0060017 8 5 0,000 9,404E-03 0,07615742 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 9,404E-03 0,0758902 ! anagen GO:0042640 6 5 0,000 9,404E-03 0,07562485 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 9,404E-03 0,07536135 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 9,404E-03 0,07509968 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 9,404E-03 0,07483982 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 9,404E-03 0,07458175 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 9,404E-03 0,07432546 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 9,404E-03 0,07407092 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 9,404E-03 0,07381811 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 9,404E-03 0,07356703 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 9,404E-03 0,07331765 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 9,404E-03 0,07306996 ! cardiac muscle fiber development GO:0048739 7 5 0,000 9,404E-03 0,07282393 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 9,404E-03 0,07257956 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 9,404E-03 0,07233681 ! neutrophil mediated immunity GO:0002446 6 5 0,000 9,404E-03 0,07209569 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 9,404E-03 0,07185617 ! ovulation GO:0030728 6 5 0,000 9,404E-03 0,07161824 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 9,404E-03 0,07138187 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 9,404E-03 0,07114706 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 9,404E-03 0,0709138 ! response to pH GO:0009268 9 5 0,000 9,404E-03 0,07068205 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 9,404E-03 0,07045182 ! proline biosynthetic process GO:0006561 6 5 0,000 9,404E-03 0,07022308 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 9,404E-03 0,06999582 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 9,404E-03 0,06977002 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 9,404E-03 0,06954568 ! polyol catabolic process GO:0046174 7 5 0,000 9,404E-03 0,06932278 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 9,404E-03 0,0691013 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 9,404E-03 0,06888123 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 9,404E-03 0,06866256 ! sister chromatid cohesion GO:0007062 9 5 0,000 9,404E-03 0,06844528 ! nerve growth factor processing GO:0032455 7 5 0,000 9,404E-03 0,06822936 ! urea metabolic process GO:0019627 6 5 0,000 9,404E-03 0,0680148 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 9,404E-03 0,06780159 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 9,404E-03 0,06758971 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 9,404E-03 0,06737915 ! neutrophil activation GO:0042119 5 5 0,000 9,404E-03 0,0671699 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 9,404E-03 0,06696194 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 9,404E-03 0,06675527 ! response to food GO:0032094 5 5 0,000 9,404E-03 0,06654987 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 9,404E-03 0,06634573 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,404E-03 0,06614284 ! paraxial mesoderm development GO:0048339 9 5 0,000 9,404E-03 0,06594118 ! forebrain neuron development GO:0021884 7 5 0,000 9,404E-03 0,06574075 ! melanosome organization GO:0032438 7 5 0,000 9,404E-03 0,06554154 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 9,404E-03 0,06534353 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 9,404E-03 0,06514671 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 9,404E-03 0,06495107 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,404E-03 0,06475661 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 9,404E-03 0,06456331 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 9,404E-03 0,06437115 ! nucleoside transport GO:0015858 6 5 0,000 9,404E-03 0,06418014 ! nucleoside salvage GO:0043174 7 5 0,000 9,404E-03 0,06399026 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 9,404E-03 0,0638015 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,404E-03 0,06361385 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 9,404E-03 0,0634273 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 9,404E-03 0,06324184 ! early endosome to late endosome transport GO:0045022 11 5 0,000 9,404E-03 0,06305746 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,404E-03 0,06287415 ! depyrimidination GO:0045008 8 5 0,000 9,404E-03 0,06269191 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 9,404E-03 0,06251072 ! 5S class rRNA transcription GO:0042791 8 5 0,000 9,404E-03 0,06233057 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 9,404E-03 0,06215146 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,404E-03 0,06197337 ! neuronal ion channel clustering GO:0045161 7 5 0,000 9,404E-03 0,06179631 ! sodium ion homeostasis GO:0055078 6 5 0,000 9,404E-03 0,06162025 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 9,404E-03 0,06144519 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 9,404E-03 0,06127113 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 9,404E-03 0,06109804 ! monocyte differentiation GO:0030224 8 5 0,000 9,404E-03 0,06092594 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 9,404E-03 0,0607548 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 9,404E-03 0,06058462 ! centrosome duplication GO:0051298 5 5 0,000 9,404E-03 0,06041538 ! response to UV-C GO:0010225 6 5 0,000 9,404E-03 0,0602471 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 9,404E-03 0,06007974 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 9,404E-03 0,05991332 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 9,404E-03 0,05974781 ! regulation of dendrite development GO:0050773 12 5 0,000 9,404E-03 0,05958322 ! peptidyl-arginine modification GO:0018195 7 5 0,000 9,404E-03 0,05941953 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,404E-03 0,05925673 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 9,404E-03 0,05909483 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 9,404E-03 0,05893381 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 9,404E-03 0,05877366 ! regulation of dopamine secretion GO:0014059 12 5 0,000 9,404E-03 0,05861438 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 9,404E-03 0,05845597 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 9,404E-03 0,0582984 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 9,404E-03 0,05814169 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 9,404E-03 0,05798581 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 9,404E-03 0,05783077 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 9,404E-03 0,05767655 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 9,404E-03 0,05752316 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 9,404E-03 0,05737058 ! neural tube patterning GO:0021532 6 5 0,000 9,404E-03 0,0572188 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 9,404E-03 0,05706783 ! histone demethylation GO:0016577 9 5 0,000 9,404E-03 0,05691765 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 9,404E-03 0,05676826 ! regulation of sterol transport GO:0032371 7 5 0,000 9,404E-03 0,05661965 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 9,404E-03 0,05647182 ! enteric nervous system development GO:0048484 8 5 0,000 9,404E-03 0,05632476 ! establishment of planar polarity GO:0001736 6 5 0,000 9,404E-03 0,05617846 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 9,404E-03 0,05603292 ! muscle cell proliferation GO:0033002 8 5 0,000 9,404E-03 0,05588813 ! transcription termination GO:0006353 8 5 0,000 9,404E-03 0,05574409 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 9,404E-03 0,05560079 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 9,404E-03 0,05545822 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 9,404E-03 0,05531639 ! regulation of respiratory burst GO:0060263 8 5 0,000 9,404E-03 0,05517527 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 9,404E-03 0,05503488 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 9,404E-03 0,0548952 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 9,404E-03 0,05475622 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 9,404E-03 0,05461795 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 9,404E-03 0,05448037 ! apical protein localization GO:0045176 6 5 0,000 9,404E-03 0,05434349 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 9,404E-03 0,05420729 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,404E-03 0,05407177 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 9,404E-03 0,05393693 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 9,404E-03 0,05380276 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 9,404E-03 0,05366925 ! triglyceride catabolic process GO:0019433 6 5 0,000 9,404E-03 0,05353641 ! glial cell migration GO:0008347 10 5 0,000 9,404E-03 0,05340422 ! determination of adult lifespan GO:0008340 8 5 0,000 9,404E-03 0,05327268 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 9,404E-03 0,05314179 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 9,404E-03 0,05301154 GO:0007439|ectodermal gut development, ! somatic stem cell maintenance GO:0035019 13 5 0,000 9,404E-03 0,05288193 ! cerebellar cortex formation GO:0021697 6 5 0,000 9,404E-03 0,05275295 ! neural plate development GO:0001840 6 5 0,000 9,404E-03 0,05262459 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 9,404E-03 0,05249686 ! regulation of sensory perception GO:0051931 6 5 0,000 9,404E-03 0,05236975 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 9,404E-03 0,05224326 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 9,404E-03 0,05211737 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 9,404E-03 0,05199209 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 9,404E-03 0,0518674 ! sensory cilium assembly GO:0035058 6 5 0,000 9,404E-03 0,05174332 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 9,404E-03 0,05161983 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 9,404E-03 0,05149692 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 9,404E-03 0,0513746 ! spindle assembly GO:0051225 5 5 0,000 9,404E-03 0,05125286 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 9,404E-03 0,0511317 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 9,404E-03 0,0510111 ! protein amino acid prenylation GO:0018346 9 5 0,000 9,404E-03 0,05089108 ! organ regeneration GO:0031100 7 5 0,000 9,404E-03 0,05077161 ! NAD biosynthetic process GO:0009435 7 5 0,000 9,404E-03 0,05065271 ! carnitine metabolic process GO:0009437 5 5 0,000 9,404E-03 0,05053436 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 9,404E-03 0,05041657 GO:0055081|anion homeostasis, ! T cell activation GO:0042110 134 79 1,000 9,723E-03 0,05200649 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01020076 0,05443561 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,01044352 0,05560208 GO:0060348|bone development, ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,01118712 0,05942352 ! regulation of membrane potential GO:0042391 128 85 1,000 0,01118712 0,0592866 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,01118712 0,05915031 ! tRNA transcription GO:0009304 11 6 0,000 0,01127423 0,05947413 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01127423 0,05933803 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01127423 0,05920255 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01127423 0,0590677 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01127423 0,05893345 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01127423 0,05879982 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01127423 0,05866679 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01127423 0,05853435 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01127423 0,05840252 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01127423 0,05827128 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01127423 0,05814063 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01127423 0,05801056 ! prostate gland development GO:0030850 9 6 0,000 0,01127423 0,05788107 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01127423 0,05775216 GO:0046580|negative regulation of Ras protein signal transduction, ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01127423 0,05762382 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01127423 0,05749605 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01127423 0,05736885 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01127423 0,05724221 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01127423 0,05711612 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01127423 0,05699059 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01127423 0,05686561 ! neuron adhesion GO:0007158 9 6 0,000 0,01127423 0,05674118 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01127423 0,05661729 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01127423 0,05649394 ! signal peptide processing GO:0006465 8 6 0,000 0,01127423 0,05637113 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01127423 0,05624885 ! mRNA stabilization GO:0048255 15 6 0,000 0,01127423 0,0561271 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01127423 0,05600587 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01127423 0,05588517 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01127423 0,05576499 ! opsonization GO:0008228 8 6 0,000 0,01127423 0,05564532 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01127423 0,05552616 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01127423 0,05540752 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01127423 0,05528938 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01127423 0,05517174 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01127423 0,05505461 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01127423 0,05493796 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01127423 0,05482182 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01127423 0,05470616 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01127423 0,05459099 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01127423 0,0544763 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01127423 0,05436209 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01127423 0,05424837 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01127423 0,05413511 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01127423 0,05402233 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01127423 0,05391002 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01127423 0,05379817 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01127423 0,05368679 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01127423 0,05357587 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01127423 0,0534654 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01127423 0,05335539 ! thymic T cell selection GO:0045061 12 6 0,000 0,01127423 0,05324583 ! protein lipoylation GO:0009249 10 6 0,000 0,01127423 0,05313672 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01127423 0,05302806 ! pigment granule organization GO:0048753 11 6 0,000 0,01127423 0,05291983 ! drug transport GO:0015893 6 6 0,000 0,01127423 0,05281206 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01127423 0,05270471 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01127423 0,05259781 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01127423 0,05249133 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01127423 0,05238529 ! histidine metabolic process GO:0006547 6 6 0,000 0,01127423 0,05227968 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01127423 0,05217449 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01127423 0,05206972 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01127423 0,05196537 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01127423 0,05186144 ! adenohypophysis development GO:0021984 10 6 0,000 0,01127423 0,05175792 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01127423 0,05165482 ! hyperosmotic response GO:0006972 8 6 0,000 0,01127423 0,05155213 ! microtubule nucleation GO:0007020 10 6 0,000 0,01127423 0,05144984 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01127423 0,05134796 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01127423 0,05124648 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01127423 0,0511454 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01127423 0,05104472 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01127423 0,05094444 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01127423 0,05084455 ! response to dietary excess GO:0002021 7 6 0,000 0,01127423 0,05074505 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01127423 0,05064594 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01127423 0,05054721 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01127423 0,05044887 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01127423 0,05035091 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01127423 0,05025333 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01127423 0,05015613 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01127423 0,0500593 ! neuron apoptosis GO:0051402 8 6 0,000 0,01127423 0,04996285 ! organic alcohol transport GO:0015850 9 6 0,000 0,01127423 0,04986677 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01127423 0,04977105 ! male sex determination GO:0030238 9 6 0,000 0,01127423 0,04967571 ! carnitine transport GO:0015879 8 6 0,000 0,01127423 0,04958072 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01127423 0,04948611 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01127423 0,04939185 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01127423 0,04929794 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01127423 0,0492044 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01127423 0,04911121 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01127423 0,04901837 ! parturition GO:0007567 12 6 0,000 0,01127423 0,04892588 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01127423 0,04883375 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01127423 0,04874195 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01127423 0,0486505 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01127423 0,0485594 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01127423 0,04846863 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01127423 0,04837821 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01127423 0,04828812 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01127423 0,04819836 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01127423 0,04810894 ! macrophage differentiation GO:0030225 10 6 0,000 0,01127423 0,04801985 ! astrocyte development GO:0014002 14 6 0,000 0,01127423 0,04793109 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01127423 0,04784266 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01127423 0,04775455 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01127423 0,04766676 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01127423 0,0475793 ! eating behavior GO:0042755 6 6 0,000 0,01127423 0,04749216 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01127423 0,04740534 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01127423 0,04731883 ! response to copper ion GO:0046688 9 6 0,000 0,01127423 0,04723264 ! DNA topological change GO:0006265 8 6 0,000 0,01127423 0,04714676 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01127423 0,0470612 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01127423 0,04697594 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01127423 0,04689099 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01127423 0,04680635 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01127423 0,04672202 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01127423 0,04663798 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01127423 0,04655425 ! hair follicle maturation GO:0048820 7 6 0,000 0,01127423 0,04647082 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01127423 0,04638769 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01127423 0,04630486 ! Schwann cell development GO:0014044 14 6 0,000 0,01127423 0,04622232 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01127423 0,04614007 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01127423 0,04605812 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01127423 0,04597645 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01127423 0,04589508 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01127423 0,04581399 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01127423 0,04573319 ! histone ubiquitination GO:0016574 7 6 0,000 0,01127423 0,04565267 ! regulation of meiosis GO:0040020 10 6 0,000 0,01127423 0,04557244 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01127423 0,04549249 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01127423 0,04541282 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01127423 0,04533342 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01127423 0,04525431 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01127423 0,04517547 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01127423 0,0450969 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01127423 0,04501861 ! receptor internalization GO:0031623 9 6 0,000 0,01127423 0,04494059 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01127423 0,04486284 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01127423 0,04478535 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01127423 0,04470814 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01127423 0,04463119 ! protein deubiquitination GO:0016579 8 6 0,000 0,01127423 0,0445545 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01127423 0,04447808 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01127423 0,04440192 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01127423 0,04432602 ! axonal fasciculation GO:0007413 9 6 0,000 0,01127423 0,04425037 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01127423 0,04417499 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01127423 0,04409986 ! midbrain development GO:0030901 6 6 0,000 0,01127423 0,04402499 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01127423 0,04395037 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01127423 0,04387601 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01127423 0,04380189 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01127423 0,04372803 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01127423 0,04365441 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01127423 0,04358104 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01127423 0,04350792 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01127423 0,04343504 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01127423 0,04336241 ! adult feeding behavior GO:0008343 6 6 0,000 0,01127423 0,04329002 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01127423 0,04321787 ! blastocyst growth GO:0001832 15 6 0,000 0,01127423 0,04314596 ! pigment granule transport GO:0051904 12 6 0,000 0,01127423 0,04307428 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01127423 0,04300285 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01127423 0,04293165 ! catecholamine transport GO:0051937 7 6 0,000 0,01127423 0,04286069 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01127423 0,04278997 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01127423 0,04271947 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01127423 0,04264921 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01127423 0,04257918 ! protein prenylation GO:0018342 10 6 0,000 0,01127423 0,04250938 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01127423 0,0424398 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01127423 0,04237046 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01127423 0,04230134 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,01169552 0,04381059 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,01169552 0,04373935 ! cell fate commitment GO:0045165 141 92 1,000 0,01301027 0,04857731 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01314124 0,0489868 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01314124 0,04890753 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01314124 0,04882852 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01314124 0,04874976 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01314124 0,04867126 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01314124 0,04859301 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01314124 0,04851501 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01314124 0,04843726 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01314124 0,04835976 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01314124 0,04828251 ! reproductive behavior GO:0019098 12 7 0,000 0,01314124 0,04820551 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01314124 0,04812875 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01314124 0,04805223 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01314124 0,04797596 ! oligopeptide transport GO:0006857 11 7 0,000 0,01314124 0,04789993 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01314124 0,04782413 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01314124 0,04774858 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,01314124 0,04767327 ! pericardium development GO:0060039 8 7 0,000 0,01314124 0,04759819 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01314124 0,04752335 ! fibril organization GO:0043206 13 7 0,000 0,01314124 0,04744875 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01314124 0,04737438 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01314124 0,04730024 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01314124 0,04722633 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01314124 0,04715266 ! lipoprotein transport GO:0042953 9 7 0,000 0,01314124 0,04707921 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01314124 0,04700599 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01314124 0,046933 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01314124 0,04686024 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01314124 0,0467877 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01314124 0,04671538 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01314124 0,04664329 ! chemosensory behavior GO:0007635 9 7 0,000 0,01314124 0,04657142 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01314124 0,04649977 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01314124 0,04642835 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01314124 0,04635714 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01314124 0,04628615 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01314124 0,04621537 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01314124 0,04614481 ! reflex GO:0060004 12 7 0,000 0,01314124 0,04607447 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01314124 0,04600434 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01314124 0,04593443 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01314124 0,04586472 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01314124 0,04579523 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01314124 0,04572595 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01314124 0,04565688 ! spinal cord patterning GO:0021511 7 7 0,000 0,01314124 0,04558801 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01314124 0,04551936 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01314124 0,04545091 ! adrenal gland development GO:0030325 17 7 0,000 0,01314124 0,04538266 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01314124 0,04531462 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01314124 0,04524679 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01314124 0,04517915 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01314124 0,04511172 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01314124 0,04504449 ! endosome organization GO:0007032 10 7 0,000 0,01314124 0,04497746 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01314124 0,04491063 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01314124 0,044844 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01314124 0,04477756 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01314124 0,04471132 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01314124 0,04464528 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01314124 0,04457943 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01314124 0,04451377 ! galactose metabolic process GO:0006012 10 7 0,000 0,01314124 0,04444831 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01314124 0,04438304 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01314124 0,04431797 ! organ growth GO:0035265 11 7 0,000 0,01314124 0,04425308 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01314124 0,04418838 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01314124 0,04412387 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01314124 0,04405955 ! retinol metabolic process GO:0042572 9 7 0,000 0,01314124 0,04399542 ! behavioral fear response GO:0001662 13 7 0,000 0,01314124 0,04393147 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01314124 0,04386771 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01314124 0,04380413 ! rRNA modification GO:0000154 12 7 0,000 0,01314124 0,04374074 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01314124 0,04367753 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01314124 0,04361451 ! response to UV-B GO:0010224 11 7 0,000 0,01314124 0,04355166 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01314124 0,043489 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01314124 0,04342651 ! intermediate filament organization GO:0045109 11 7 0,000 0,01314124 0,04336421 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01314124 0,04330208 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01314124 0,04324013 ! fibrinolysis GO:0042730 9 7 0,000 0,01314124 0,04317836 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01314124 0,04311677 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01314124 0,04305535 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01314124 0,0429941 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01314124 0,04293303 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01314124 0,04287213 ! response to tropane GO:0014073 13 7 0,000 0,01314124 0,04281141 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01314124 0,04275085 ! melanosome localization GO:0032400 10 7 0,000 0,01314124 0,04269047 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01314124 0,04263026 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01314124 0,04257022 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01314124 0,04251034 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01314124 0,04245064 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01314124 0,0423911 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01314124 0,04233173 ! mast cell activation GO:0045576 9 7 0,000 0,01314124 0,04227252 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01314124 0,04221348 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01314124 0,04215461 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01314124 0,0420959 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01314124 0,04203735 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01314124 0,04197896 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01314124 0,04192074 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01314124 0,04186268 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01314124 0,04180478 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01314124 0,04174703 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01314124 0,04168945 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01314124 0,04163203 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01314124 0,04157476 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01314124 0,04151766 ! response to tumor cell GO:0002347 12 7 0,000 0,01314124 0,0414607 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01314124 0,04140391 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01314124 0,04134727 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01314124 0,04129078 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01314124 0,04123445 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01314124 0,04117827 ! diuresis GO:0030146 12 7 0,000 0,01314124 0,04112225 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01314124 0,04106638 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01314124 0,04101066 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01314124 0,04095509 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01314124 0,04089967 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01314124 0,0408444 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01314124 0,04078928 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01314124 0,0407343 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01314124 0,04067948 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01314124 0,0406248 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01314124 0,04057027 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01314124 0,04051589 ! lymph node development GO:0048535 9 7 0,000 0,01314124 0,04046165 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01314124 0,04040756 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01314124 0,04035361 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01314124 0,0402998 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01314124 0,04024614 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01314124 0,04019262 ! ATP catabolic process GO:0006200 10 7 0,000 0,01314124 0,04013925 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01314124 0,04008601 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01314124 0,04003292 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01314124 0,03997996 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01314124 0,03992715 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01314124 0,03987448 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01314124 0,03982194 ! muscle adaptation GO:0043500 12 7 0,000 0,01314124 0,03976954 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01314124 0,03971728 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01314124 0,03966516 ! retina homeostasis GO:0001895 9 7 0,000 0,01314124 0,03961318 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01314124 0,03956133 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01314124 0,03950961 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01314124 0,03945803 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01314124 0,03940659 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01314124 0,03935528 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01314124 0,0393041 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01314124 0,03925306 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,01328064 0,039618 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,01328064 0,03956669 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,01410643 0,04197257 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01410643 0,04191834 ! calcium ion transport GO:0006816 167 99 1,000 0,01495403 0,04437969 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01500484 0,0444731 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01500484 0,04441586 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01500484 0,04435877 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01500484 0,04430183 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01500484 0,04424503 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01500484 0,04418838 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01500484 0,04413187 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01500484 0,04407551 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01500484 0,04401929 ! phosphate transport GO:0006817 10 8 0,000 0,01500484 0,04396321 ! N-glycan processing GO:0006491 12 8 0,000 0,01500484 0,04390728 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01500484 0,04385149 ! UTP metabolic process GO:0046051 8 8 0,000 0,01500484 0,04379584 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01500484 0,04374033 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01500484 0,04368497 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01500484 0,04362974 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01500484 0,04357465 ! succinate metabolic process GO:0006105 14 8 0,000 0,01500484 0,0435197 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01500484 0,04346489 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01500484 0,04341022 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01500484 0,04335568 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01500484 0,04330128 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01500484 0,04324702 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01500484 0,0431929 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01500484 0,0431389 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01500484 0,04308505 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01500484 0,04303133 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01500484 0,04297774 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01500484 0,04292428 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01500484 0,04287096 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01500484 0,04281777 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01500484 0,04276471 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01500484 0,04271179 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01500484 0,04265899 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,01500484 0,04260633 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01500484 0,04255379 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01500484 0,04250138 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01500484 0,04244911 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01500484 0,04239696 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01500484 0,04234494 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01500484 0,04229304 ! melanin metabolic process GO:0006582 12 8 0,000 0,01500484 0,04224128 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01500484 0,04218964 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01500484 0,04213812 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01500484 0,04208674 ! macrophage activation GO:0042116 12 8 0,000 0,01500484 0,04203547 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01500484 0,04198434 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01500484 0,04193332 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01500484 0,04188243 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01500484 0,04183167 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01500484 0,04178102 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01500484 0,0417305 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01500484 0,0416801 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01500484 0,04162982 ! ruffle organization GO:0031529 11 8 0,000 0,01500484 0,04157967 ! osteoblast development GO:0002076 13 8 0,000 0,01500484 0,04152963 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01500484 0,04147972 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01500484 0,04142992 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01500484 0,04138024 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01500484 0,04133069 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01500484 0,04128125 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01500484 0,04123193 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01500484 0,04118273 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01500484 0,04113364 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01500484 0,04108467 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01500484 0,04103582 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01500484 0,04098708 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01500484 0,04093846 ! segment specification GO:0007379 10 8 0,000 0,01500484 0,04088996 ! cellular extravasation GO:0045123 11 8 0,000 0,01500484 0,04084157 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01500484 0,04079329 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01500484 0,04074513 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01500484 0,04069708 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01500484 0,04064914 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01500484 0,04060132 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,01500484 0,04055361 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01500484 0,04050601 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01500484 0,04045853 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01500484 0,04041115 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01500484 0,04036389 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01500484 0,04031673 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01500484 0,04026969 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01500484 0,04022275 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01500484 0,04017593 ! icosanoid secretion GO:0032309 12 8 0,000 0,01500484 0,04012921 GO:0050482|arachidonic acid secretion, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01500484 0,04008261 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01500484 0,04003611 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01500484 0,03998971 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01500484 0,03994343 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01500484 0,03989725 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01500484 0,03985118 ! sterol catabolic process GO:0016127 9 8 0,000 0,01500484 0,03980522 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01500484 0,03975936 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01500484 0,03971361 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01500484 0,03966796 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01500484 0,03962242 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01500484 0,03957698 ! prophase GO:0051324 11 8 0,000 0,01500484 0,03953164 ! S phase GO:0051320 8 8 0,000 0,01500484 0,03948641 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01500484 0,03944128 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01500484 0,03939626 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01500484 0,03935134 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01500484 0,03930652 ! hormone catabolic process GO:0042447 13 8 0,000 0,01500484 0,0392618 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01500484 0,03921719 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01500484 0,03917267 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01500484 0,03912826 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01500484 0,03908395 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01500484 0,03903973 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01500484 0,03899562 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01500484 0,03895161 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01500484 0,03890769 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01500484 0,03886388 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01500484 0,03882016 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01500484 0,03877654 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01500484 0,03873302 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01500484 0,0386896 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01500484 0,03864628 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01500484 0,03860305 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01500484 0,03855991 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,01524136 0,03912402 ! divalent metal ion transport GO:0070838 171 100 1,000 0,01524136 0,0390804 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01686502 0,04319548 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01686502 0,04314744 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01686502 0,04309949 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01686502 0,04305166 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01686502 0,04300393 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01686502 0,04295631 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01686502 0,04290879 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01686502 0,04286138 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01686502 0,04281407 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01686502 0,04276686 ! GTP metabolic process GO:0046039 9 9 0,000 0,01686502 0,04271976 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01686502 0,04267277 ! social behavior GO:0035176 14 9 0,000 0,01686502 0,04262587 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01686502 0,04257908 ! artery development GO:0060840 19 9 0,000 0,01686502 0,0425324 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01686502 0,04248581 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01686502 0,04243933 ! response to pain GO:0048265 16 9 0,000 0,01686502 0,04239295 ! protein complex disassembly GO:0043241 17 9 0,000 0,01686502 0,04234666 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01686502 0,04230049 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01686502 0,04225441 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01686502 0,04220843 ! lung alveolus development GO:0048286 17 9 0,000 0,01686502 0,04216255 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01686502 0,04211677 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01686502 0,04207109 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01686502 0,04202551 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01686502 0,04198003 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01686502 0,04193464 ! protein targeting to ER GO:0045047 19 9 0,000 0,01686502 0,04188936 ! T cell selection GO:0045058 18 9 0,000 0,01686502 0,04184417 ! endoderm development GO:0007492 12 9 0,000 0,01686502 0,04179908 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01686502 0,04175409 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01686502 0,04170919 ! arginine catabolic process GO:0006527 10 9 0,000 0,01686502 0,04166439 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01686502 0,04161968 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01686502 0,04157508 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01686502 0,04153056 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01686502 0,04148614 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01686502 0,04144182 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01686502 0,04139759 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01686502 0,04135346 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01686502 0,04130942 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01686502 0,04126547 ! mannose metabolic process GO:0006013 9 9 0,000 0,01686502 0,04122162 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01686502 0,04117786 ! receptor clustering GO:0043113 15 9 0,000 0,01686502 0,04113419 ! epithelial cell development GO:0002064 10 9 0,000 0,01686502 0,04109062 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01686502 0,04104714 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01686502 0,04100375 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01686502 0,04096045 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01686502 0,04091724 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01686502 0,04087413 ! motor axon guidance GO:0008045 14 9 0,000 0,01686502 0,0408311 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,01686502 0,04078817 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01686502 0,04074532 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01686502 0,04070257 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01686502 0,0406599 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01686502 0,04061732 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01686502 0,04057484 ! DNA ligation GO:0006266 14 9 0,000 0,01686502 0,04053244 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01686502 0,04049013 ! response to amine stimulus GO:0014075 13 9 0,000 0,01686502 0,04044791 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01686502 0,04040578 ! erythrocyte development GO:0048821 11 9 0,000 0,01686502 0,04036373 ! renal water homeostasis GO:0003091 14 9 0,000 0,01686502 0,04032177 ! postreplication repair GO:0006301 11 9 0,000 0,01686502 0,0402799 ! mRNA cleavage GO:0006379 13 9 0,000 0,01686502 0,04023812 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01686502 0,04019642 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,01686502 0,04015481 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01686502 0,04011328 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01686502 0,04007184 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01686502 0,04003049 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01686502 0,03998922 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01686502 0,03994804 ! acid secretion GO:0046717 14 9 0,000 0,01686502 0,03990694 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01686502 0,03986592 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01686502 0,03982499 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01686502 0,03978415 ! purine base metabolic process GO:0006144 18 9 0,000 0,01686502 0,03974339 ! thymus development GO:0048538 15 9 0,000 0,01686502 0,03970271 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01686502 0,03966211 ! spleen development GO:0048536 15 9 0,000 0,01686502 0,0396216 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01686502 0,03958117 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01686502 0,03954082 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01686502 0,03950055 ! detection of calcium ion GO:0005513 13 9 0,000 0,01686502 0,03946037 ! blastocyst formation GO:0001825 12 9 0,000 0,01686502 0,03942027 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01686502 0,03938025 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01686502 0,03934031 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01686502 0,03930045 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01686502 0,03926067 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01686502 0,03922098 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01686502 0,03918136 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01686502 0,03914182 ! prepulse inhibition GO:0060134 14 9 0,000 0,01686502 0,03910236 ! embryonic placenta development GO:0001892 12 9 0,000 0,01686502 0,03906299 ! insulin secretion GO:0030073 17 9 0,000 0,01686502 0,03902369 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01686502 0,03898447 ! response to nicotine GO:0035094 16 9 0,000 0,01686502 0,03894533 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01686502 0,03890626 ! nucleus localization GO:0051647 15 9 0,000 0,01686502 0,03886728 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01686502 0,03882837 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,0187218 0,04306013 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,0187218 0,04301711 ! neuron fate specification GO:0048665 11 10 0,000 0,0187218 0,04297418 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,0187218 0,04293134 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,0187218 0,04288858 ! thyroid gland development GO:0030878 19 10 0,000 0,0187218 0,0428459 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,0187218 0,04280331 ! synapsis GO:0007129 13 10 0,000 0,0187218 0,04276081 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,0187218 0,04271838 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,0187218 0,04267605 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,0187218 0,04263379 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,0187218 0,04259162 ! sulfate transport GO:0008272 12 10 0,000 0,0187218 0,04254954 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,0187218 0,04250753 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,0187218 0,04246561 ! androgen metabolic process GO:0008209 13 10 0,000 0,0187218 0,04242377 ! phospholipid efflux GO:0033700 16 10 0,000 0,0187218 0,04238202 ! hippocampus development GO:0021766 19 10 0,000 0,0187218 0,04234034 ! blood vessel remodeling GO:0001974 21 10 0,000 0,0187218 0,04229875 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,0187218 0,04225724 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,0187218 0,04221581 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,0187218 0,04217447 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,0187218 0,0421332 ! pathogenesis GO:0009405 13 10 0,000 0,0187218 0,04209201 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,0187218 0,04205091 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0187218 0,04200988 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,0187218 0,04196894 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,0187218 0,04192807 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,0187218 0,04188729 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,0187218 0,04184658 ! melanocyte differentiation GO:0030318 15 10 0,000 0,0187218 0,04180595 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,0187218 0,0417654 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,0187218 0,04172493 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0187218 0,04168454 ! response to X-ray GO:0010165 16 10 0,000 0,0187218 0,04164423 ! B cell proliferation GO:0042100 14 10 0,000 0,0187218 0,04160399 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,0187218 0,04156383 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,0187218 0,04152375 ! forebrain cell migration GO:0021885 17 10 0,000 0,0187218 0,04148375 ! lipid digestion GO:0044241 15 10 0,000 0,0187218 0,04144382 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,0187218 0,04140397 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,0187218 0,0413642 ! UV protection GO:0009650 14 10 0,000 0,0187218 0,0413245 ! fear response GO:0042596 16 10 0,000 0,0187218 0,04128488 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,0187218 0,04124534 ! negative regulation of ossification GO:0030279 19 10 0,000 0,0187218 0,04120587 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,0187218 0,04116647 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,0187218 0,04112715 ! regulation of bone resorption GO:0045124 24 10 0,000 0,0187218 0,04108791 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,0187218 0,04104874 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,0187218 0,04100965 ! regulation of organ growth GO:0046620 11 10 0,000 0,0187218 0,04097063 ! response to dsRNA GO:0043331 18 10 0,000 0,0187218 0,04093168 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,0187218 0,04089281 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0187218 0,04085401 ! embryonic axis specification GO:0000578 12 10 0,000 0,0187218 0,04081529 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,0187218 0,04077664 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,0187218 0,04073806 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,0187218 0,04069956 ! cranial nerve development GO:0021545 12 10 0,000 0,0187218 0,04066112 ! fucose catabolic process GO:0019317 16 10 0,000 0,0187218 0,04062276 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,0187218 0,04058448 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,0187218 0,04054626 ! protein sumoylation GO:0016925 12 10 0,000 0,0187218 0,04050812 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,0187218 0,04047005 ! zymogen activation GO:0031638 14 10 0,000 0,0187218 0,04043205 ! salivary gland development GO:0007431 22 10 0,000 0,0187218 0,04039412 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0187218 0,04035626 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,0187218 0,04031847 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,0187218 0,04028076 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,0187218 0,04024311 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,0187218 0,04020554 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0187218 0,04016803 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,0187218 0,0401306 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,0187218 0,04009323 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,0187218 0,04005594 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,0187218 0,04001871 ! detection of bacterium GO:0016045 10 10 0,000 0,0187218 0,03998155 ! embryonic gut development GO:0048566 11 10 0,000 0,0187218 0,03994446 ! activation of innate immune response GO:0002218 10 10 0,000 0,0187218 0,03990744 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,0187218 0,03987049 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,0187218 0,03983361 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,0187218 0,03979679 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,0187218 0,03976005 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,0187218 0,03972337 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,0187218 0,03968676 ! rRNA transcription GO:0009303 17 11 0,000 0,02057517 0,04357541 ! respiratory burst GO:0045730 14 11 0,000 0,02057517 0,04353532 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02057517 0,04349531 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02057517 0,04345537 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02057517 0,0434155 ! virus-host interaction GO:0019048 17 11 0,000 0,02057517 0,04337571 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02057517 0,04333598 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02057517 0,04329634 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02057517 0,04325676 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02057517 0,04321726 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02057517 0,04317782 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02057517 0,04313846 ! mating GO:0007618 14 11 0,000 0,02057517 0,04309918 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02057517 0,04305996 ! T cell proliferation GO:0042098 20 11 0,000 0,02057517 0,04302081 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02057517 0,04298174 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02057517 0,04294274 ! bone resorption GO:0045453 16 11 0,000 0,02057517 0,0429038 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02057517 0,04286494 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02057517 0,04282615 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02057517 0,04278743 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02057517 0,04274878 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02057517 0,04271019 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02057517 0,04267168 ! syncytium formation GO:0006949 15 11 0,000 0,02057517 0,04263324 ! plasma membrane organization GO:0007009 18 11 0,000 0,02057517 0,04259486 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02057517 0,04255656 ! focal adhesion formation GO:0048041 24 11 0,000 0,02057517 0,04251832 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02057517 0,04248016 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02057517 0,04244206 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02057517 0,04240403 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02057517 0,04236607 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02057517 0,04232817 ! adult heart development GO:0007512 11 11 0,000 0,02057517 0,04229034 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02057517 0,04225258 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02057517 0,04221489 ! temperature homeostasis GO:0001659 16 11 0,000 0,02057517 0,04217727 ! L-glutamate transport GO:0015813 16 11 0,000 0,02057517 0,04213971 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02057517 0,04210222 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02057517 0,0420648 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02057517 0,04202744 ! stem cell development GO:0048864 29 11 0,000 0,02057517 0,04199015 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,02057517 0,04195292 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02057517 0,04191576 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02057517 0,04187867 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02057517 0,04184164 ! vasoconstriction GO:0042310 15 11 0,000 0,02057517 0,04180468 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02057517 0,04176778 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02057517 0,04173095 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02057517 0,04169418 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02057517 0,04165748 ! ribosome assembly GO:0042255 13 11 0,000 0,02057517 0,04162084 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02057517 0,04158427 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02057517 0,04154776 ! chromatin silencing GO:0006342 19 11 0,000 0,02057517 0,04151131 ! nucleosome positioning GO:0016584 13 11 0,000 0,02057517 0,04147493 ! T cell homeostasis GO:0043029 20 11 0,000 0,02057517 0,04143861 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02057517 0,04140236 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02057517 0,04136617 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02057517 0,04133004 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02057517 0,04129397 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02057517 0,04125797 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02057517 0,04122203 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02057517 0,04118616 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02057517 0,04115034 ! male genitalia development GO:0030539 13 11 0,000 0,02057517 0,04111459 ! cholesterol efflux GO:0033344 19 11 0,000 0,02057517 0,0410789 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02057517 0,04104327 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02057517 0,04100771 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02057517 0,0409722 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02057517 0,04093676 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02057517 0,04090138 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02057517 0,04086606 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02057517 0,0408308 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02057517 0,0407956 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02057517 0,04076046 ! lysogeny GO:0030069 18 11 0,000 0,02057517 0,04072538 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02057517 0,04069037 ! acrosome reaction GO:0007340 13 11 0,000 0,02057517 0,04065541 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02057517 0,04062051 ! lactation GO:0007595 20 12 0,000 0,02242515 0,04423486 ! reproductive cellular process GO:0048610 14 12 0,000 0,02242515 0,04419696 ! tRNA modification GO:0006400 14 12 0,000 0,02242515 0,04415912 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02242515 0,04412134 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02242515 0,04408363 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02242515 0,04404599 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02242515 0,04400841 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02242515 0,04397089 ! non-recombinational repair GO:0000726 19 12 0,000 0,02242515 0,04393343 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02242515 0,04389604 ! peroxisomal transport GO:0043574 21 12 0,000 0,02242515 0,04385872 ! cartilage condensation GO:0001502 18 12 0,000 0,02242515 0,04382145 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02242515 0,04378425 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02242515 0,04374712 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,02242515 0,04371004 ! heart looping GO:0001947 15 12 0,000 0,02242515 0,04367303 ! palate development GO:0060021 15 12 0,000 0,02242515 0,04363608 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,02242515 0,0435992 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02242515 0,04356237 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02242515 0,04352561 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02242515 0,04348891 ! arginine metabolic process GO:0006525 13 12 0,000 0,02242515 0,04345228 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02242515 0,0434157 ! methionine metabolic process GO:0006555 13 12 0,000 0,02242515 0,04337919 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02242515 0,04334273 ! Golgi organization GO:0007030 18 12 0,000 0,02242515 0,04330634 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02242515 0,04327001 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02242515 0,04323374 ! monoamine transport GO:0015844 13 12 0,000 0,02242515 0,04319753 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02242515 0,04316138 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02242515 0,04312529 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02242515 0,04308927 ! L-amino acid transport GO:0015807 20 12 0,000 0,02242515 0,0430533 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02242515 0,04301739 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02242515 0,04298154 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02242515 0,04294575 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02242515 0,04291003 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02242515 0,04287436 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02242515 0,04283875 ! cerebellum development GO:0021549 13 12 0,000 0,02242515 0,0428032 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02242515 0,0427677 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02242515 0,04273227 ! histone methylation GO:0016571 15 12 0,000 0,02242515 0,0426969 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02242515 0,04266158 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02242515 0,04262632 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02242515 0,04259112 ! response to gamma radiation GO:0010332 20 12 0,000 0,02242515 0,04255598 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02242515 0,0425209 ! intestinal absorption GO:0050892 19 12 0,000 0,02242515 0,04248587 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02242515 0,04245091 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02242515 0,042416 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02242515 0,04238114 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02242515 0,04234635 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02242515 0,04231161 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02242515 0,04227693 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02242515 0,0422423 ! microspike assembly GO:0030035 23 12 0,000 0,02242515 0,04220773 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02242515 0,04217322 ! response to cold GO:0009409 14 12 0,000 0,02242515 0,04213877 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02427175 0,04557144 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02427175 0,04553427 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02427175 0,04549716 ! water transport GO:0006833 17 13 0,000 0,02427175 0,04546011 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02427175 0,04542312 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02427175 0,04538619 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02427175 0,04534932 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02427175 0,04531251 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02427175 0,04527576 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02427175 0,04523907 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02427175 0,04520244 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02427175 0,04516587 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02427175 0,04512936 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02427175 0,0450929 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02427175 0,04505651 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02427175 0,04502017 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02427175 0,0449839 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02427175 0,04494768 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02427175 0,04491152 ! NAD metabolic process GO:0019674 21 13 0,000 0,02427175 0,04487541 ! exocrine system development GO:0035272 27 13 0,000 0,02427175 0,04483937 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02427175 0,04480338 ! bone mineralization GO:0030282 15 13 0,000 0,02427175 0,04476745 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02427175 0,04473158 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02427175 0,04469577 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02427175 0,04466001 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02427175 0,04462431 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02427175 0,04458867 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02427175 0,04455308 ! genitalia development GO:0048806 15 13 0,000 0,02427175 0,04451756 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02427175 0,04448208 ! cellular pigmentation GO:0033059 24 13 0,000 0,02427175 0,04444667 ! tissue regeneration GO:0042246 21 13 0,000 0,02427175 0,04441131 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02427175 0,044376 ! cofactor transport GO:0051181 19 13 0,000 0,02427175 0,04434076 ! NADP metabolic process GO:0006739 18 13 0,000 0,02427175 0,04430557 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02427175 0,04427043 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02427175 0,04423535 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02427175 0,04420033 ! gas transport GO:0015669 18 13 0,000 0,02427175 0,04416536 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02427175 0,04413045 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02427175 0,04409559 ! regulation of axon extension GO:0030516 23 13 0,000 0,02427175 0,04406078 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02427175 0,04402604 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02427175 0,04399134 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02427175 0,0439567 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02427175 0,04392212 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02427175 0,04388759 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02427175 0,04385311 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,02611496 0,04714631 ! superoxide anion generation GO:0042554 18 14 0,000 0,02611496 0,04710933 ! neuron maturation GO:0042551 21 14 0,000 0,02611496 0,04707241 ! regulation of S phase GO:0033261 18 14 0,000 0,02611496 0,04703555 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,02611496 0,04699875 ! myotube differentiation GO:0014902 21 14 0,000 0,02611496 0,046962 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,02611496 0,04692531 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,02611496 0,04688868 ! inositol metabolic process GO:0006020 20 14 0,000 0,02611496 0,0468521 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,02611496 0,04681559 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,02611496 0,04677913 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,02611496 0,04674272 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,02611496 0,04670637 ! gene silencing by RNA GO:0031047 20 14 0,000 0,02611496 0,04667008 ! response to cAMP GO:0051591 19 14 0,000 0,02611496 0,04663385 ! limbic system development GO:0021761 25 14 0,000 0,02611496 0,04659767 ! startle response GO:0001964 21 14 0,000 0,02611496 0,04656155 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,02611496 0,04652548 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,02611496 0,04648947 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,02611496 0,04645352 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,02611496 0,04641762 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,02611496 0,04638177 ! glycine metabolic process GO:0006544 22 14 0,000 0,02611496 0,04634599 ! pituitary gland development GO:0021983 23 14 0,000 0,02611496 0,04631025 ! cellular response to starvation GO:0009267 21 14 0,000 0,02611496 0,04627457 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,02611496 0,04623895 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,02611496 0,04620338 ! regulation of heart rate GO:0002027 23 14 0,000 0,02611496 0,04616787 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,02611496 0,04613241 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,02611496 0,046097 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,02611496 0,04606165 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,02611496 0,04602636 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,02611496 0,04599112 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,02611496 0,04595593 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,02611496 0,04592079 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,02611496 0,04588571 ! axon cargo transport GO:0008088 27 14 0,000 0,02611496 0,04585068 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,02611496 0,04581571 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,02611496 0,04578079 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,02611496 0,04574592 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,02611496 0,04571111 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02611496 0,04567635 ! mRNA splice site selection GO:0006376 26 14 0,000 0,02611496 0,04564164 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,02611496 0,04560698 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,02611496 0,04557238 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,02611496 0,04553783 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,02611496 0,04550333 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,02611496 0,04546888 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,02611496 0,04543449 ! muscle maintenance GO:0046716 19 14 0,000 0,02611496 0,04540015 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,02611496 0,04536586 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,02611496 0,04533162 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,02611496 0,04529743 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,02611496 0,0452633 ! cell killing GO:0001906 20 14 0,000 0,02611496 0,04522921 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,02611496 0,04519518 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,02611496 0,0451612 ! cilium assembly GO:0042384 20 14 0,000 0,02611496 0,04512727 ! peptide hormone secretion GO:0030072 23 14 0,000 0,02611496 0,04509339 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,02795479 0,04823407 ! positive regulation of cell size GO:0045793 20 15 0,000 0,02795479 0,04819791 ! metencephalon development GO:0022037 19 15 0,000 0,02795479 0,04816181 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,02795479 0,04812576 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,02795479 0,04808976 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,02795479 0,04805382 ! skin development GO:0043588 25 15 0,000 0,02795479 0,04801793 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,02795479 0,0479821 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,02795479 0,04794632 ! lipid phosphorylation GO:0046834 23 15 0,000 0,02795479 0,04791059 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,02795479 0,04787492 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,02795479 0,0478393 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,02795479 0,04780373 ! bile acid metabolic process GO:0008206 22 15 0,000 0,02795479 0,04776821 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,02795479 0,04773275 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,02795479 0,04769734 ! adult walking behavior GO:0007628 25 15 0,000 0,02795479 0,04766198 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,02795479 0,04762668 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,02795479 0,04759142 ! myoblast differentiation GO:0045445 27 15 0,000 0,02795479 0,04755622 ! centrosome cycle GO:0007098 16 15 0,000 0,02795479 0,04752107 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,02795479 0,04748598 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,02795479 0,04745093 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,02795479 0,04741594 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,02795479 0,047381 ! cerebral cortex development GO:0021987 29 15 0,000 0,02795479 0,04734611 ! response to osmotic stress GO:0006970 22 15 0,000 0,02795479 0,04731127 ! vesicle coating GO:0006901 25 15 0,000 0,02795479 0,04727648 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,02795479 0,04724174 ! DNA integration GO:0015074 22 15 0,000 0,02795479 0,04720706 ! peptide secretion GO:0002790 27 15 0,000 0,02795479 0,04717242 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,02795479 0,04713784 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,02795479 0,04710331 ! neuron recognition GO:0008038 22 15 0,000 0,02795479 0,04706882 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,02795479 0,04703439 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,02795479 0,04700001 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,02795479 0,04696568 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,02795479 0,0469314 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,02795479 0,04689716 ! biomineral formation GO:0031214 18 15 0,000 0,02795479 0,04686298 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,02795479 0,04682885 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,02795479 0,04679477 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,02795479 0,04676074 ! dopamine metabolic process GO:0042417 30 15 0,000 0,02795479 0,04672675 ! organic cation transport GO:0015695 19 15 0,000 0,02795479 0,04669282 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,02795479 0,04665894 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,02795479 0,0466251 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,02795479 0,04659131 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,02795479 0,04655758 ! defense response to virus GO:0051607 27 15 0,000 0,02795479 0,04652389 ! peptide hormone processing GO:0016486 19 15 0,000 0,02795479 0,04649025 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,02795479 0,04645666 ! protein secretion GO:0009306 27 16 0,000 0,02979125 0,04947284 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,02979125 0,04943714 ! hormone secretion GO:0046879 25 16 0,000 0,02979125 0,0494015 ! bone remodeling GO:0046849 24 16 0,000 0,02979125 0,04936591 ! endothelial cell migration GO:0043542 22 16 0,000 0,02979125 0,04933036 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,02979125 0,04929488 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02979125 0,04925944 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,02979125 0,04922405 ! glial cell development GO:0021782 24 16 0,000 0,02979125 0,04918871 ! patterning of blood vessels GO:0001569 24 16 0,000 0,02979125 0,04915343 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,02979125 0,04911819 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,02979125 0,04908301 ! protein polyubiquitination GO:0000209 26 16 0,000 0,02979125 0,04904787 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,02979125 0,04901279 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,02979125 0,04897775 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,02979125 0,04894277 ! fructose metabolic process GO:0006000 20 16 0,000 0,02979125 0,04890784 ! regulation of protein binding GO:0043393 27 16 0,000 0,02979125 0,04887295 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,02979125 0,04883812 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,02979125 0,04880333 ! protein export from nucleus GO:0006611 24 16 0,000 0,02979125 0,0487686 ! negative regulation of immune response GO:0050777 28 16 0,000 0,02979125 0,04873391 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,02979125 0,04869927 ! DNA replication initiation GO:0006270 25 16 0,000 0,02979125 0,04866469 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,02979125 0,04863015 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,02979125 0,04859566 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,02979125 0,04856122 ! diencephalon development GO:0021536 25 16 0,000 0,02979125 0,04852683 ! neural crest cell migration GO:0001755 24 16 0,000 0,02979125 0,04849248 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,02979125 0,04845819 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,02979125 0,04842394 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,02979125 0,04838974 ! steroid catabolic process GO:0006706 22 16 0,000 0,02979125 0,04835559 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,02979125 0,04832149 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,02979125 0,04828744 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,02979125 0,04825343 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,02979125 0,04821948 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,02979125 0,04818557 ! sperm-egg recognition GO:0035036 16 16 0,000 0,02979125 0,04815171 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,02979125 0,04811789 ! nerve development GO:0021675 18 16 0,000 0,02979125 0,04808412 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,02979125 0,0480504 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,02979125 0,04801673 ! negative regulation of translation GO:0017148 22 16 0,000 0,02979125 0,04798311 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03162435 0,05089993 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03162435 0,05086434 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03162435 0,05082879 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,03162435 0,0507933 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03162435 0,05075785 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03162435 0,05072246 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03162435 0,05068711 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03162435 0,05065181 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03162435 0,05061656 ! signal complex assembly GO:0007172 29 17 0,000 0,03162435 0,05058136 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03162435 0,05054621 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,03162435 0,05051111 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03162435 0,05047606 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03162435 0,05044106 ! memory GO:0007613 25 17 0,000 0,03162435 0,0504061 ! keratinization GO:0031424 17 17 0,000 0,03162435 0,05037119 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03162435 0,05033633 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03162435 0,05030152 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03162435 0,05026676 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03162435 0,05023205 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03162435 0,05019738 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03162435 0,05016276 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03162435 0,05012819 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03162435 0,05009367 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03162435 0,05005919 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03162435 0,05002476 ! membrane budding GO:0006900 29 17 0,000 0,03162435 0,04999038 ! heme metabolic process GO:0042168 27 17 0,000 0,03162435 0,04995605 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03162435 0,04992176 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03162435 0,04988752 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03162435 0,04985333 ! body fluid secretion GO:0007589 27 17 0,000 0,03162435 0,04981918 ! stem cell differentiation GO:0048863 36 17 0,000 0,03162435 0,04978508 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03162435 0,04975103 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03162435 0,04971702 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03162435 0,04968306 ! sensory perception of pain GO:0019233 23 17 0,000 0,03162435 0,04964915 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03162435 0,04961528 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03162435 0,04958146 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03162435 0,04954769 ! synaptogenesis GO:0007416 24 17 0,000 0,03162435 0,04951396 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03162435 0,04948027 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03162435 0,04944664 ! cell-cell junction organization GO:0045216 25 17 0,000 0,03162435 0,04941304 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03162435 0,0493795 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03162435 0,049346 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03162435 0,04931254 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03162435 0,04927913 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03162435 0,04924577 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03162435 0,04921245 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03345409 0,05202461 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03345409 0,05198946 ! positive regulation of translation GO:0045727 28 18 0,000 0,03345409 0,05195436 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03345409 0,0519193 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03345409 0,05188429 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03345409 0,05184933 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03345409 0,05181441 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03345409 0,05177954 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03345409 0,05174472 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03345409 0,05170995 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03345409 0,05167522 ! axis specification GO:0009798 26 18 0,000 0,03345409 0,05164054 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03345409 0,0516059 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,03345409 0,05157132 ! pancreas development GO:0031016 26 18 0,000 0,03345409 0,05153677 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03345409 0,05150228 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03345409 0,05146783 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03345409 0,05143342 ! response to retinoic acid GO:0032526 25 18 0,000 0,03345409 0,05139907 ! pigmentation during development GO:0048066 31 18 0,000 0,03345409 0,05136475 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03345409 0,05133049 ! fucose metabolic process GO:0006004 26 18 0,000 0,03345409 0,05129627 ! response to fungus GO:0009620 19 18 0,000 0,03345409 0,05126209 ! peptide cross-linking GO:0018149 31 18 0,000 0,03345409 0,05122796 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03345409 0,05119388 ! heart process GO:0003015 27 18 0,000 0,03345409 0,05115984 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03345409 0,05112585 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03345409 0,0510919 ! visual learning GO:0008542 35 18 0,000 0,03345409 0,051058 ! somitogenesis GO:0001756 24 18 0,000 0,03345409 0,05102414 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03345409 0,05099033 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03345409 0,05095656 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03345409 0,05092283 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03345409 0,05088916 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03345409 0,05085552 ! vitamin transport GO:0051180 24 18 0,000 0,03345409 0,05082193 ! hormone transport GO:0009914 27 18 0,000 0,03345409 0,05078838 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03345409 0,05075488 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03345409 0,05072143 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03345409 0,05068801 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03345409 0,05065464 ! cell-cell recognition GO:0009988 20 18 0,000 0,03345409 0,05062132 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03345409 0,05058804 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03345409 0,0505548 ! regulation of glucose import GO:0046324 21 18 0,000 0,03345409 0,0505216 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03345409 0,05048845 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03345409 0,05045535 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03345409 0,05042228 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03345409 0,05038926 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,03528047 0,05310543 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,03528047 0,05307069 ! positive regulation of ossification GO:0045778 30 19 0,000 0,03528047 0,05303601 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,03528047 0,05300137 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,03528047 0,05296677 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,03528047 0,05293222 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,03528047 0,05289771 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,03528047 0,05286325 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,03528047 0,05282884 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,03528047 0,05279446 ! regeneration GO:0031099 32 19 0,000 0,03528047 0,05276014 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,03528047 0,05272586 ! response to alkaloid GO:0043279 32 19 0,000 0,03528047 0,05269162 ! sensory perception of taste GO:0050909 23 19 0,000 0,03528047 0,05265742 ! smooth muscle contraction GO:0006939 36 19 0,000 0,03528047 0,05262328 ! peroxisome organization GO:0007031 29 19 0,000 0,03528047 0,05258917 ! digestive system process GO:0022600 30 19 0,000 0,03528047 0,05255511 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,03528047 0,05252109 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,03528047 0,05248712 ! response to vitamin A GO:0033189 26 19 0,000 0,03528047 0,05245319 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,03528047 0,05241931 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,03528047 0,05238547 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,03528047 0,05235167 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,03528047 0,05231792 ! response to starvation GO:0042594 30 19 0,000 0,03528047 0,05228421 ! sex determination GO:0007530 29 19 0,000 0,03528047 0,05225054 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,03528047 0,05221692 ! plasma membrane fusion GO:0045026 23 19 0,000 0,03528047 0,05218334 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,03528047 0,0521498 ! cytolysis GO:0019835 20 19 0,000 0,03528047 0,05211631 ! renal system process GO:0003014 35 19 0,000 0,03528047 0,05208286 ! vasodilation GO:0042311 33 19 0,000 0,03528047 0,05204945 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,03528047 0,05201608 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,03528047 0,05198276 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,03528047 0,05194948 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,03528047 0,05191625 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,03528047 0,05188305 ! sarcomere organization GO:0045214 23 19 0,000 0,03528047 0,0518499 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,03528047 0,05181679 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,03528047 0,05178372 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,03528047 0,0517507 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,03528047 0,05171771 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,03528047 0,05168477 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,03528047 0,05165187 ! protein stabilization GO:0050821 26 19 0,000 0,03528047 0,05161902 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,03710351 0,0542518 ! iron ion transport GO:0006826 37 20 0,000 0,03710351 0,05421733 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,03710351 0,05418291 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,03710351 0,05414853 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,03710351 0,05411419 ! response to vitamin GO:0033273 29 20 0,000 0,03710351 0,0540799 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,03710351 0,05404565 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,03710351 0,05401145 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,03710351 0,05397728 ! spinal cord development GO:0021510 31 20 0,000 0,03710351 0,05394316 ! response to ethanol GO:0045471 37 20 0,000 0,03710351 0,05390909 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,03710351 0,05387505 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,03710351 0,05384106 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,03710351 0,05380711 ! chromosome condensation GO:0030261 31 20 0,000 0,03710351 0,05377321 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,03710351 0,05373935 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,03710351 0,05370553 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,03710351 0,05367175 ! pallium development GO:0021543 38 20 0,000 0,03710351 0,05363802 ! DNA modification GO:0006304 28 20 0,000 0,03710351 0,05360432 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,03710351 0,05357067 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,03710351 0,05353707 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,03710351 0,0535035 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,03710351 0,05346998 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,03710351 0,0534365 ! collagen catabolic process GO:0030574 25 20 0,000 0,03710351 0,05340306 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,03710351 0,05336966 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,03710351 0,0533363 ! alditol metabolic process GO:0019400 24 20 0,000 0,03710351 0,05330299 ! actin filament-based movement GO:0030048 34 20 0,000 0,03710351 0,05326971 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,03892321 0,05584741 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,03892321 0,05581259 GO:0016444|somatic cell DNA recombination, ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,03892321 0,05577781 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,03892321 0,05574308 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,03892321 0,0557084 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,03892321 0,05567375 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,03892321 0,05563915 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,03892321 0,05560459 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,03892321 0,05557008 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,03892321 0,0555356 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,03892321 0,05550117 ! phototransduction GO:0007602 25 21 0,000 0,03892321 0,05546678 ! dendrite development GO:0016358 35 21 0,000 0,03892321 0,05543244 ! visual behavior GO:0007632 39 21 0,000 0,03892321 0,05539814 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,03892321 0,05536388 ! ovarian follicle development GO:0001541 30 21 0,000 0,03892321 0,05532966 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,03892321 0,05529549 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,03892321 0,05526135 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,03892321 0,05522726 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,03892321 0,05519321 ! cell aging GO:0007569 32 21 0,000 0,03892321 0,05515921 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,03892321 0,05512524 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,03892321 0,05509132 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,03892321 0,05505744 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,03892321 0,0550236 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,03892321 0,0549898 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,03892321 0,05495604 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,03892321 0,05492233 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,03892321 0,05488865 ! fatty acid transport GO:0015908 30 21 0,000 0,03892321 0,05485502 ! immunoglobulin production GO:0002377 33 21 0,000 0,03892321 0,05482143 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,03892321 0,05478788 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,03892321 0,05475437 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,03892321 0,0547209 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,03892321 0,05468747 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,03892321 0,05465408 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,03892321 0,05462074 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,03892321 0,05458743 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,03892321 0,05455417 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,03892321 0,05452094 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,03892321 0,05448776 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,03892321 0,05445462 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,03892321 0,05442151 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,03892321 0,05438845 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,03892321 0,05435543 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04073958 0,05685742 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04073958 0,05682294 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04073958 0,0567885 ! viral genome replication GO:0019079 29 22 0,000 0,04073958 0,05675411 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04073958 0,05671975 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04073958 0,05668544 ! molting cycle process GO:0022404 40 22 0,000 0,04073958 0,05665117 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04073958 0,05661694 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04073958 0,05658275 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04073958 0,0565486 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04073958 0,05651449 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04073958 0,05648043 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04073958 0,0564464 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04073958 0,05641242 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,04073958 0,05637848 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,04073958 0,05634458 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,04073958 0,05631071 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04073958 0,05627689 ! regulation of behavior GO:0050795 38 22 0,000 0,04073958 0,05624311 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04073958 0,05620938 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04073958 0,05617568 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04073958 0,05614202 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04073958 0,0561084 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04073958 0,05607482 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04073958 0,05604128 ! blastocyst development GO:0001824 37 22 0,000 0,04073958 0,05600779 ! neural tube closure GO:0001843 33 22 0,000 0,04073958 0,05597433 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04073958 0,05594091 ! protein tetramerization GO:0051262 39 22 0,000 0,04073958 0,05590753 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,04255261 0,05836077 ! neuron fate commitment GO:0048663 32 23 0,000 0,04255261 0,05832599 ! embryonic pattern specification GO:0009880 31 23 0,000 0,04255261 0,05829125 ! myelination GO:0042552 35 23 0,000 0,04255261 0,05825655 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,04255261 0,0582219 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,04255261 0,05818728 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,04255261 0,05815271 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,04255261 0,05811818 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,04255261 0,05808369 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,04255261 0,05804923 ! osteoblast differentiation GO:0001649 40 23 0,000 0,04255261 0,05801482 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,04255261 0,05798046 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,04255261 0,05794613 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,04255261 0,05791184 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,04255261 0,05787759 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,04255261 0,05784339 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,04255261 0,05780922 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,04255261 0,05777509 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,04255261 0,05774101 ! cell fate determination GO:0001709 45 23 0,000 0,04255261 0,05770696 ! pentose metabolic process GO:0019321 31 23 0,000 0,04255261 0,05767296 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,04255261 0,05763899 ! spermatid development GO:0007286 33 23 0,000 0,04255261 0,05760507 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,04255261 0,05757118 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,04255261 0,05753734 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,04255261 0,05750353 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,04255261 0,05746976 ! telomere organization GO:0032200 32 23 0,000 0,04255261 0,05743604 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,04255261 0,05740235 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,04255261 0,0573687 ! regulation of amine transport GO:0051952 38 23 0,000 0,04255261 0,0573351 ! liver development GO:0001889 40 23 0,000 0,04255261 0,05730153 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,04436232 0,05970354 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,04436232 0,05966862 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,04436232 0,05963375 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,04436232 0,05959892 ! superoxide metabolic process GO:0006801 32 24 0,000 0,04436232 0,05956413 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,04436232 0,05952937 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,04436232 0,05949466 ! fat cell differentiation GO:0045444 37 24 0,000 0,04436232 0,05945999 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,04436232 0,05942536 ! sperm motility GO:0030317 27 24 0,000 0,04436232 0,05939077 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,04436232 0,05935622 ! vacuole organization GO:0007033 39 24 0,000 0,04436232 0,05932171 ! receptor metabolic process GO:0043112 37 24 0,000 0,04436232 0,05928724 ! neural crest cell development GO:0014032 39 24 0,000 0,04436232 0,05925281 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,04436232 0,05921843 ! primary neural tube formation GO:0014020 35 24 0,000 0,04436232 0,05918408 ! negative regulation of cell development GO:0010721 56 24 0,000 0,04436232 0,05914977 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,04436232 0,0591155 ! base-excision repair GO:0006284 31 24 0,000 0,04436232 0,05908127 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,04436232 0,05904708 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,04436232 0,05901292 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,04436232 0,05897881 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,04436232 0,05894474 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,04616872 0,0613095 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,04616872 0,06127412 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,04616872 0,06123879 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,04616872 0,06120349 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,04616872 0,06116823 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,04616872 0,06113302 ! peptide transport GO:0015833 43 25 0,000 0,04616872 0,06109785 ! male gonad development GO:0008584 33 25 0,000 0,04616872 0,06106271 ! iron ion homeostasis GO:0055072 39 25 0,000 0,04616872 0,06102762 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,04616872 0,06099256 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,04616872 0,06095755 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,04616872 0,06092258 ! phospholipid transport GO:0015914 35 25 0,000 0,04616872 0,06088765 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,04616872 0,06085275 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,04616872 0,0608179 ! detection of light stimulus GO:0009583 30 25 0,000 0,04616872 0,06078309 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,04616872 0,06074832 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,04616872 0,06071358 ! leukocyte proliferation GO:0070661 39 25 0,000 0,04616872 0,06067889 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,04616872 0,06064424 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,0479718 0,06297668 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,0479718 0,06294076 ! translational initiation GO:0006413 43 26 0,000 0,0479718 0,06290487 ! regulation of pH GO:0006885 36 26 0,000 0,0479718 0,06286903 ! circadian rhythm GO:0007623 42 26 0,000 0,0479718 0,06283323 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,0479718 0,06279747 ! post-embryonic development GO:0009791 42 26 0,000 0,0479718 0,06276175 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,0479718 0,06272606 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,0479718 0,06269043 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,0479718 0,06265483 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,0479718 0,06261927 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,0479718 0,06258375 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,0479718 0,06254827 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,04977158 0,06485815 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,04977158 0,06482143 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,04977158 0,06478474 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,04977158 0,0647481 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,04977158 0,0647115 ! catechol metabolic process GO:0009712 43 27 0,000 0,04977158 0,06467494 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,04977158 0,06463842 ! acute-phase response GO:0006953 42 27 0,000 0,04977158 0,06460194 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,04977158 0,0645655 ! myofibril assembly GO:0030239 36 27 0,000 0,04977158 0,06452911 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,04977158 0,06449275 ! response to ionizing radiation GO:0010212 47 27 0,000 0,04977158 0,06445644 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,04977158 0,06442017 ! natural killer cell activation GO:0030101 35 27 0,000 0,04977158 0,06438394 ! lipid oxidation GO:0034440 38 27 0,000 0,04977158 0,06434774 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,04977158 0,06431159 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,04977158 0,06427548 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,04977158 0,06423942 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,04977158 0,06420339 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,04977158 0,0641674 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,04977158 0,06413145 ! gene silencing GO:0016458 41 27 0,000 0,04977158 0,06409554 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,05156806 0,06637187 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,05156806 0,06633475 ! phenol metabolic process GO:0018958 44 28 0,000 0,05156806 0,06629767 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,05156806 0,06626064 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,05156806 0,06622364 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,05156806 0,06618669 ! cell junction assembly GO:0034329 56 28 0,000 0,05156806 0,06614977 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,05156806 0,0661129 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,05156806 0,06607607 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,05156806 0,06603928 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,05156806 0,06600253 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,05156806 0,06596582 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,05156806 0,06592915 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,05156806 0,06589252 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,05156806 0,06585594 ! mesoderm formation GO:0001707 46 28 0,000 0,05156806 0,06581939 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,05156806 0,06578288 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,05156806 0,06574642 ! ensheathment of neurons GO:0007272 43 28 0,000 0,05156806 0,06570999 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,05156806 0,06567361 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,05156806 0,06563727 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,05156806 0,06560096 ! neural tube formation GO:0001841 41 28 0,000 0,05156806 0,0655647 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,05156806 0,06552847 ! placenta development GO:0001890 37 28 0,000 0,05156806 0,06549229 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,05336125 0,06773227 ! regulation of innate immune response GO:0045088 38 29 0,000 0,05336125 0,06769491 ! ovulation cycle process GO:0022602 41 29 0,000 0,05336125 0,06765759 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,05336125 0,06762031 ! protein targeting to membrane GO:0006612 53 29 0,000 0,05336125 0,06758308 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,05336125 0,06754588 ! mismatch repair GO:0006298 34 29 0,000 0,05336125 0,06750873 ! muscle cell development GO:0055001 38 29 0,000 0,05336125 0,06747161 ! formation of primary germ layer GO:0001704 48 29 0,000 0,05336125 0,06743454 ! telencephalon development GO:0021537 52 29 0,000 0,05336125 0,06739751 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,05336125 0,06736052 ! eye morphogenesis GO:0048592 51 29 0,000 0,05336125 0,06732357 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,05336125 0,06728666 ! tissue homeostasis GO:0001894 42 29 0,000 0,05336125 0,06724979 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,05515114 0,06946749 ! collagen metabolic process GO:0032963 40 30 0,000 0,05515114 0,06942946 ! organic anion transport GO:0015711 51 30 0,000 0,05515114 0,06939148 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,05515114 0,06935354 ! spliceosome assembly GO:0000245 49 30 0,000 0,05515114 0,06931564 ! spindle organization GO:0007051 37 30 0,000 0,05515114 0,06927779 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,05515114 0,06923997 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,05515114 0,0692022 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,05515114 0,06916447 ! ceramide metabolic process GO:0006672 43 30 0,000 0,05515114 0,06912677 ! ovulation cycle GO:0042698 43 30 0,000 0,05515114 0,06908912 ! hindbrain development GO:0030902 45 30 0,000 0,05515114 0,06905151 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,05515114 0,06901394 ! adult locomotory behavior GO:0008344 47 30 0,000 0,05515114 0,06897642 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,05515114 0,06893893 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,05515114 0,06890148 ! response to heat GO:0009408 41 30 0,000 0,05515114 0,06886408 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,05515114 0,06882671 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,05693776 0,07101781 ! negative regulation of secretion GO:0051048 49 31 0,000 0,05693776 0,07097932 ! glial cell differentiation GO:0010001 55 31 0,000 0,05693776 0,07094087 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,05693776 0,07090246 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,05693776 0,07086409 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,05693776 0,07082577 ! odontogenesis GO:0042476 50 31 0,000 0,05693776 0,07078748 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,05693776 0,07074924 ! segmentation GO:0035282 41 31 0,000 0,05693776 0,07071104 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,05693776 0,07067288 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,05693776 0,07063476 ! metanephros development GO:0001656 58 31 0,000 0,05693776 0,07059668 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,05693776 0,07055864 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,05693776 0,07052065 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,05693776 0,07048269 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,05693776 0,07044478 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,05693776 0,07040691 ! RNA modification GO:0009451 40 31 0,000 0,05693776 0,07036907 ! regulation of muscle development GO:0048634 48 32 0,000 0,0587211 0,07253412 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,0587211 0,07249518 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,0587211 0,07245629 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,0587211 0,07241744 ! meiosis I GO:0007127 52 32 0,000 0,0587211 0,07237863 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,0587211 0,07233986 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,0587211 0,07230114 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,0587211 0,07226245 ! peripheral nervous system development GO:0007422 53 32 0,000 0,0587211 0,07222381 ! regulation of protein stability GO:0031647 48 32 0,000 0,0587211 0,07218521 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,0587211 0,07214665 ! cytokine production GO:0001816 44 32 0,000 0,0587211 0,07210813 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,0587211 0,07206965 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,06050117 0,07421476 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,06050117 0,0741752 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,06050117 0,07413569 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,06050117 0,07409621 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,06050117 0,07405678 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,06050117 0,07401739 ! sister chromatid segregation GO:0000819 46 33 0,000 0,06050117 0,07397804 ! ear morphogenesis GO:0042471 42 33 0,000 0,06050117 0,07393873 ! actomyosin structure organization GO:0031032 43 33 0,000 0,06050117 0,07389946 ! cell junction organization GO:0034330 63 33 0,000 0,06050117 0,07386024 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,06050117 0,07382105 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,06050117 0,07378191 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,06050117 0,07374281 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,06050117 0,07370375 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,06050117 0,07366473 ! female gonad development GO:0008585 49 33 0,000 0,06050117 0,07362576 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,06050117 0,07358682 ! positive regulation of cell development GO:0010720 54 33 0,000 0,06050117 0,07354793 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,06050117 0,07350908 ! regulation of proteolysis GO:0030162 50 33 0,000 0,06050117 0,07347027 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,06050117 0,0734315 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,06050117 0,07339277 ! cytokinesis GO:0000910 52 33 0,000 0,06050117 0,07335408 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,06050117 0,07331543 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,06227797 0,07542882 ! mRNA catabolic process GO:0006402 48 34 0,000 0,06227797 0,07538912 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,06227797 0,07534947 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,06227797 0,07530985 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,06227797 0,07527028 ! feeding behavior GO:0007631 45 34 0,000 0,06227797 0,07523074 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,06227797 0,07519125 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,06227797 0,0751518 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,06227797 0,07511239 ! neuron migration GO:0001764 46 34 0,000 0,06227797 0,07507303 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,06227797 0,0750337 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,06227797 0,07499442 ! polyol metabolic process GO:0019751 44 34 0,000 0,06227797 0,07495517 ! aerobic respiration GO:0009060 47 34 0,000 0,06227797 0,07491597 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,06227797 0,07487681 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,06227797 0,07483769 ! embryonic organ development GO:0048568 45 34 0,000 0,06227797 0,07479861 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,06227797 0,07475957 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,06405152 0,07684846 ! Notch signaling pathway GO:0007219 56 35 0,000 0,06405152 0,07680839 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,06405152 0,07676836 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,06405152 0,07672838 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,06405152 0,07668844 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,06405152 0,07664854 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,06405152 0,07660868 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,06405152 0,07656886 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,06405152 0,07652909 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,06405152 0,07648935 ! pigment metabolic process GO:0042440 61 35 0,000 0,06405152 0,07644966 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,06582181 0,07852187 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,06582181 0,07848116 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,06582181 0,0784405 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,06582181 0,07839988 ! negative regulation of binding GO:0051100 58 36 0,000 0,06582181 0,0783593 ! neural tube development GO:0021915 50 36 0,000 0,06582181 0,07831876 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,06582181 0,07827826 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,06582181 0,07823781 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,06582181 0,0781974 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,06582181 0,07815703 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,06758886 0,08021381 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,06758886 0,08017244 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,06758886 0,08013112 ! learning GO:0007612 67 37 0,000 0,06758886 0,08008983 ! ion transmembrane transport GO:0034220 56 37 0,000 0,06758886 0,08004859 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,06758886 0,08000739 ! regulation of protein secretion GO:0050708 51 37 0,000 0,06758886 0,07996624 ! amino acid activation GO:0043038 52 37 0,000 0,06758886 0,07992513 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,06758886 0,07988405 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,06935266 0,08192661 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,06935266 0,08188456 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,06935266 0,08184254 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,06935266 0,08180057 ! phagocytosis GO:0006909 60 38 0,000 0,06935266 0,08175865 ! mesenchymal cell development GO:0014031 64 38 0,000 0,06935266 0,08171676 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,06935266 0,08167492 ! maintenance of location in cell GO:0051651 69 38 0,000 0,06935266 0,08163312 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,07111323 0,08366262 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,07111323 0,08361985 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,07111323 0,08357712 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,07111323 0,08353444 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,07111323 0,0834918 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,07111323 0,0834492 ! male sex differentiation GO:0046661 53 39 0,000 0,07111323 0,08340664 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,07111323 0,08336413 ! chromatin remodeling GO:0006338 68 39 0,000 0,07111323 0,08332166 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,07111323 0,08327924 ! JNK cascade GO:0007254 54 39 0,000 0,07111323 0,08323686 ! developmental growth GO:0048589 62 39 0,000 0,07111323 0,08319452 ! synapse organization GO:0050808 55 39 0,000 0,07111323 0,08315223 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,07287057 0,08516377 ! response to calcium ion GO:0051592 58 40 0,000 0,07287057 0,08512052 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,07287057 0,08507731 ! regulation of tube size GO:0035150 60 40 0,000 0,07287057 0,08503415 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,07287057 0,08499103 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,07287057 0,08494795 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,07287057 0,08490492 ! peptide metabolic process GO:0006518 56 40 0,000 0,07287057 0,08486193 ! inner ear development GO:0048839 57 40 0,000 0,07287057 0,08481898 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,07287057 0,08477608 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,07287057 0,08473322 ! double-strand break repair GO:0006302 67 40 0,000 0,07287057 0,0846904 ! B cell differentiation GO:0030183 62 40 0,000 0,07287057 0,08464763 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,07287057 0,0846049 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,07287057 0,08456221 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,07462468 0,0865541 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,07462468 0,08651047 ! glucose transport GO:0015758 52 41 0,000 0,07462468 0,08646689 ! endosome transport GO:0016197 71 41 0,000 0,07462468 0,08642335 ! striated muscle contraction GO:0006941 62 41 0,000 0,07462468 0,08637985 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,07462468 0,0863364 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,07462468 0,086293 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,07462468 0,08624963 ! biopolymer methylation GO:0043414 62 41 0,000 0,07462468 0,08620631 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,07462468 0,08616304 ! mitochondrial transport GO:0006839 60 42 0,000 0,07637558 0,08814041 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,07637558 0,0880962 ! cellular component disassembly GO:0022411 64 42 0,000 0,07637558 0,08805205 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,07637558 0,08800793 ! hexose transport GO:0008645 54 42 0,000 0,07637558 0,08796386 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,07637558 0,08791984 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,07637558 0,08787585 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,07637558 0,08783192 ! excretion GO:0007588 63 42 0,000 0,07637558 0,08778802 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,07637558 0,08774417 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,07637558 0,08770037 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,07637558 0,0876566 ! regulation of cell shape GO:0008360 78 42 0,000 0,07637558 0,08761288 ! positive regulation of binding GO:0051099 59 43 0,000 0,07812326 0,08957303 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,07812326 0,0895284 ! neuromuscular process GO:0050905 79 43 0,000 0,07812326 0,08948382 ! activation of caspase activity GO:0006919 65 43 0,000 0,07812326 0,08943928 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,07812326 0,08939478 ! tRNA processing GO:0008033 49 43 0,000 0,07812326 0,08935033 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,07812326 0,08930592 ! response to insulin stimulus GO:0032868 63 43 0,000 0,07812326 0,08926155 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,07812326 0,08921723 ! methylation GO:0032259 64 43 0,000 0,07812326 0,08917296 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,07986774 0,09111895 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,07986774 0,09107377 ! glycolysis GO:0006096 53 44 0,000 0,07986774 0,09102864 ! regulation of action potential GO:0001508 71 44 0,000 0,07986774 0,09098356 ! regulation of ion transport GO:0043269 57 44 0,000 0,07986774 0,09093852 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,07986774 0,09089352 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,07986774 0,09084857 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,07986774 0,09080366 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,07986774 0,0907588 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,07986774 0,09071398 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,07986774 0,0906692 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,07986774 0,09062447 ! RNA catabolic process GO:0006401 64 45 0,000 0,08160902 0,0925546 ! positive regulation of defense response GO:0031349 59 45 0,000 0,08160902 0,09250899 ! regulation of translational initiation GO:0006446 64 45 0,000 0,08160902 0,09246342 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,08160902 0,09241789 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,08160902 0,09237241 ! cell recognition GO:0008037 58 45 0,000 0,08160902 0,09232697 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,0833471 0,09424696 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,0833471 0,09420065 ! cell redox homeostasis GO:0045454 63 46 0,000 0,0833471 0,09415438 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,0833471 0,09410816 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,0833471 0,09406198 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,08508199 0,09597281 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,08508199 0,09592577 ! endocrine system development GO:0035270 83 47 0,000 0,08508199 0,09587877 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,08508199 0,09583182 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,08508199 0,09578491 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,08508199 0,09573805 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,08508199 0,09569123 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,08508199 0,09564446 ! chloride transport GO:0006821 67 48 0,000 0,08681369 0,09754347 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,08681369 0,09749585 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,08681369 0,09744826 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,08681369 0,09740073 ! gastrulation GO:0007369 73 48 0,000 0,08681369 0,09735324 ! heart morphogenesis GO:0003007 65 48 0,000 0,08681369 0,0973058 ! regulation of DNA replication GO:0006275 75 48 0,000 0,08681369 0,0972584 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,08681369 0,09721105 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,08681369 0,09716374 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,08681369 0,09711648 ! regulation of endocytosis GO:0030100 63 48 0,000 0,08681369 0,09706927 ! nuclear export GO:0051168 69 48 0,000 0,08681369 0,0970221 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,08681369 0,09697498 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,08681369 0,09692791 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,08854222 0,09880985 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,08854222 0,09876193 ! sensory perception of smell GO:0007608 61 49 0,000 0,08854222 0,09871406 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,08854222 0,09866623 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,08854222 0,09861845 ! RNA elongation GO:0006354 62 49 0,000 0,08854222 0,09857072 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,08854222 0,09852303 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,08854222 0,09847539 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,08854222 0,09842779 ! cartilage development GO:0051216 70 49 0,000 0,08854222 0,09838024 ! maintenance of location GO:0051235 84 49 0,000 0,08854222 0,09833274 ! regulation of actin filament length GO:0030832 72 50 0,000 0,09026757 0,10020049 ! ear development GO:0043583 72 50 0,000 0,09026757 0,10015216 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,09026757 0,10010387 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,09026757 0,10005562 ! lipid modification GO:0030258 73 50 0,000 0,09026757 0,10000743 ! positive regulation of growth GO:0045927 67 50 0,000 0,09026757 0,09995928 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,09026757 0,09991117 ! proton transport GO:0015992 75 50 0,000 0,09026757 0,09986312 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,09026757 0,09981511 ! positive regulation of secretion GO:0051047 71 51 0,000 0,09198976 0,10167057 ! hydrogen transport GO:0006818 77 51 0,000 0,09198976 0,10162173 ! muscle fiber development GO:0048747 74 51 0,000 0,09198976 0,10157295 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,09198976 0,10152421 ! adult behavior GO:0030534 80 51 0,000 0,09198976 0,10147552 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,09198976 0,10142687 ! transition metal ion transport GO:0000041 74 52 0,000 0,09370879 0,10327274 ! regulation of cellular component size GO:0032535 74 52 0,000 0,09370879 0,10322328 ! aging GO:0007568 79 52 0,000 0,09370879 0,10317387 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,09370879 0,1031245 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,09370879 0,10307518 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,09542466 0,10491239 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,09542466 0,10486226 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,09542466 0,10481218 ! kidney development GO:0001822 90 53 0,000 0,09542466 0,10476215 ! single fertilization GO:0007338 59 53 0,000 0,09542466 0,10471217 ! cell projection assembly GO:0030031 76 53 0,000 0,09542466 0,10466224 ! amino acid transport GO:0006865 84 54 0,000 0,09713738 0,10648997 ! regulation of mitosis GO:0007088 84 54 0,000 0,09713738 0,10643924 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,09713738 0,10638856 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,09713738 0,10633792 ! DNA catabolic process GO:0006308 67 54 0,000 0,09713738 0,10628733 ! detection of external stimulus GO:0009581 66 54 0,000 0,09713738 0,10623679 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,09713738 0,1061863 ! exocytosis GO:0006887 74 55 0,000 0,09884695 0,10800379 ! mesoderm development GO:0007498 76 55 0,000 0,09884695 0,10795251 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,09884695 0,10790128 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,09884695 0,10785009 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,10055339 0,10965993 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,10055339 0,10960796 ! carbohydrate transport GO:0008643 74 57 0,000 0,10225669 0,11141183 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,10225669 0,11135908 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,10225669 0,11130638 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,10225669 0,11125373 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,10225669 0,11120113 ! camera-type eye development GO:0043010 88 57 0,000 0,10225669 0,11114857 ! secondary metabolic process GO:0019748 84 57 0,000 0,10225669 0,11109607 ! response to peptide hormone stimulus GO:0043434 84 57 0,000 0,10225669 0,11104362 ! gonad development GO:0008406 79 57 0,000 0,10225669 0,11099121 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,10395686 0,11278339 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,10395686 0,11273021 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,10565391 0,11451649 ! activation of MAPK activity GO:0000187 84 59 0,000 0,10565391 0,11446255 ! actin filament organization GO:0007015 95 59 0,000 0,10565391 0,11440866 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,10565391 0,11435482 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,10734785 0,11613361 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,10734785 0,11607901 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,10734785 0,11602446 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,10734785 0,11596996 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,10734785 0,11591552 ! regulation of heart contraction GO:0008016 91 60 0,000 0,10734785 0,11586112 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,10734785 0,11580678 ! fertilization GO:0009566 68 60 0,000 0,10734785 0,11575248 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,10903867 0,11752059 ! cell-matrix adhesion GO:0007160 114 61 0,000 0,10903867 0,11746555 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,10903867 0,11741055 ! urogenital system development GO:0001655 101 61 0,000 0,10903867 0,11735561 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,10903867 0,11730072 ! extracellular matrix organization GO:0030198 103 61 0,000 0,10903867 0,11724588 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,10903867 0,1171911 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,10903867 0,11713636 ! amine catabolic process GO:0009310 90 62 0,000 0,11072639 0,11889388 ! neurotransmitter transport GO:0006836 81 62 0,000 0,11072639 0,1188384 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,11072639 0,11878297 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,11072639 0,1187276 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,11241101 0,12047778 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,11241101 0,12042166 ! appendage morphogenesis GO:0035107 93 64 0,000 0,11409253 0,12216611 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,11409253 0,12210927 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,11409253 0,12205247 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,11409253 0,12199573 ! hexose catabolic process GO:0019320 82 64 0,000 0,11409253 0,12193904 ! reproductive structure development GO:0048608 90 65 0,000 0,11577096 0,12367543 ! appendage development GO:0048736 94 65 0,000 0,11577096 0,12361802 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,11577096 0,12356065 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,11577096 0,12350334 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,11577096 0,12344609 ! defense response to bacterium GO:0042742 73 65 0,000 0,11577096 0,12338888 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,11577096 0,12333173 ! activation of immune response GO:0002253 83 65 0,000 0,11577096 0,12327463 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,11744631 0,1250007 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,11744631 0,12494288 ! axon guidance GO:0007411 99 66 0,000 0,11744631 0,12488512 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,11744631 0,12482741 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,11911858 0,1265463 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,11911858 0,12648787 ! acute inflammatory response GO:0002526 92 68 0,000 0,12078778 0,12820115 ! learning or memory GO:0007611 123 68 0,000 0,12078778 0,12814202 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,12078778 0,12808294 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,12078778 0,12802391 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,12078778 0,12796494 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,12078778 0,12790603 ! rhythmic process GO:0048511 105 68 0,000 0,12078778 0,12784717 ! inorganic anion transport GO:0015698 93 68 0,000 0,12078778 0,12778836 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,12245391 0,12949149 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,12245391 0,12943198 ! response to drug GO:0042493 108 69 0,000 0,12245391 0,12937253 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,12245391 0,12931313 ! response to metal ion GO:0010038 103 70 0,000 0,12411698 0,1310092 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,12411698 0,13094911 ! humoral immune response GO:0006959 86 70 0,000 0,12411698 0,13088907 ! eye development GO:0001654 111 70 0,000 0,12411698 0,13082908 ! amine transport GO:0015837 101 70 0,000 0,12411698 0,13076915 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,12411698 0,13070927 ! regulation of catabolic process GO:0009894 106 70 0,000 0,12411698 0,13064945 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,12577699 0,13233627 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,12577699 0,13227576 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,12577699 0,1322153 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,12577699 0,1321549 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,12577699 0,13209456 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,12743395 0,13377366 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,12743395 0,13371263 ! negative regulation of transport GO:0051051 116 73 0,000 0,12908787 0,13538627 ! regulation of blood pressure GO:0008217 107 73 0,000 0,12908787 0,13532457 ! tube morphogenesis GO:0035239 118 73 0,000 0,12908787 0,13526292 ! mitochondrion organization GO:0007005 104 73 0,000 0,12908787 0,13520132 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,12908787 0,13513978 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,12908787 0,1350783 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,13073875 0,13674357 ! digestion GO:0007586 97 74 0,000 0,13073875 0,13668142 ! protein import into nucleus GO:0006606 118 74 0,000 0,13073875 0,13661932 ! cellular response to hormone stimulus GO:0032870 109 74 0,000 0,13073875 0,13655727 ! blood coagulation GO:0007596 116 75 0,000 0,13238659 0,13821568 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,13238659 0,13815297 ! response to nutrient GO:0007584 104 75 0,000 0,13238659 0,13809032 ! regulation of ligase activity GO:0051340 114 75 0,000 0,13238659 0,13802772 ! nuclear import GO:0051170 121 75 0,000 0,13238659 0,13796518 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,13238659 0,13790269 ! amine biosynthetic process GO:0009309 97 76 0,000 0,1340314 0,13955284 ! tRNA metabolic process GO:0006399 95 76 0,000 0,1340314 0,13948969 ! response to unfolded protein GO:0006986 99 76 0,000 0,1340314 0,1394266 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,1340314 0,13936357 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,13567319 0,14100693 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,13567319 0,14094324 ! regulation of DNA binding GO:0051101 119 77 0,000 0,13567319 0,14087961 ! sex differentiation GO:0007548 105 77 0,000 0,13567319 0,14081603 ! protein ubiquitination GO:0016567 125 77 0,000 0,13567319 0,14075252 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,13567319 0,14068906 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,13567319 0,14062566 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,13567319 0,14056231 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,13731196 0,14219608 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,13731196 0,14213209 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,13731196 0,14206815 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,13894771 0,14369593 ! cellular respiration GO:0045333 107 79 0,000 0,13894771 0,14363134 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,13894771 0,14356682 ! regulation of lyase activity GO:0051339 133 79 0,000 0,13894771 0,14350235 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,13894771 0,14343794 ! chromatin assembly GO:0031497 102 80 0,000 0,14058046 0,14505835 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,14058046 0,1449933 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,14058046 0,14492831 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,14058046 0,14486338 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,14058046 0,14479851 ! forebrain development GO:0030900 131 80 0,000 0,14058046 0,14473369 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,14221021 0,14634608 ! hemostasis GO:0007599 125 81 0,000 0,14221021 0,14628063 ! mRNA transport GO:0051028 121 81 0,000 0,14221021 0,14621523 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,14221021 0,1461499 ! response to protein stimulus GO:0051789 111 81 0,000 0,14221021 0,14608463 ! regulation of neurological system process GO:0031644 122 81 0,000 0,14221021 0,14601941 ! vitamin metabolic process GO:0006766 103 81 0,000 0,14221021 0,14595425 ! detection of stimulus GO:0051606 108 82 0,000 0,14383696 0,14755798 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,14546071 0,14915722 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,14546071 0,14909075 ! regulation of defense response GO:0031347 117 84 0,000 0,14708149 0,15068482 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,14708149 0,15061773 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,14708149 0,1505507 ! sterol metabolic process GO:0016125 120 84 0,000 0,14708149 0,15048373 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,14869928 0,15207129 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,14869928 0,1520037 ! rRNA metabolic process GO:0016072 107 85 0,000 0,14869928 0,15193618 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,14869928 0,15186871 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,14869928 0,1518013 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,15031409 0,15338172 ! nucleosome organization GO:0034728 114 87 0,000 0,15192593 0,15495772 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,15192593 0,15488903 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,15192593 0,1548204 ! female pregnancy GO:0007565 130 87 0,000 0,15192593 0,15475184 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,15353481 0,15632141 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,15353481 0,15625224 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,15353481 0,15618314 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,15353481 0,15611409 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,15353481 0,1560451 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,15514073 0,15760763 ! reproductive developmental process GO:0003006 127 89 0,000 0,15514073 0,15753805 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,15514073 0,15746853 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,15514073 0,15739907 ! regulation of T cell activation GO:0050863 128 89 0,000 0,15514073 0,15732967 ! leukocyte differentiation GO:0002521 143 90 0,000 0,1567437 0,15888519 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,1567437 0,1588152 ! hormone metabolic process GO:0042445 121 90 0,000 0,1567437 0,15874527 ! RNA localization GO:0006403 135 91 0,000 0,15834371 0,16029513 ! ATP metabolic process GO:0046034 137 91 0,000 0,15834371 0,16022461 ! response to virus GO:0009615 122 91 0,000 0,15834371 0,16015415 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,15994078 0,16169837 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,15994078 0,16162733 ! positive regulation of immune response GO:0050778 121 92 0,000 0,15994078 0,16155634 ! DNA recombination GO:0006310 146 92 0,000 0,15994078 0,16148542 ! sulfur metabolic process GO:0006790 118 92 0,000 0,15994078 0,16141457 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,16153491 0,16295189 ! electron transport chain GO:0022900 123 94 0,000 0,16312611 0,1644849 ! response to oxidative stress GO:0006979 141 94 0,000 0,16312611 0,16441282 ! regulation of binding GO:0051098 151 95 0,000 0,16471438 0,1659409 ! angiogenesis GO:0001525 149 95 0,000 0,16471438 0,16586825 ! carboxylic acid transport GO:0046942 147 95 0,000 0,16471438 0,16579566 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,16629973 0,16731819 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,16629973 0,16724503 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,16629973 0,16717193 ! protein maturation GO:0051604 129 96 0,000 0,16629973 0,1670989 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,16788216 0,16861527 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,16788216 0,16854167 ! extracellular structure organization GO:0043062 156 99 0,000 0,17103828 0,17163527 ! protein import GO:0017038 156 99 0,000 0,17103828 0,17156042 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,17103828 0,17148564 ! regulation of translation GO:0006417 151 100 0,000 0,17261199 0,17298805 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,17261199 0,17291271 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,17261199 0,17283743 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,17261199 0,17276222 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,17261199 0,17268707 ! protein localization in organelle GO:0033365 161 100 0,000 0,17261199 0,17261199