pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/639-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 3,474E-07 8,359E-04 ! interphase GO:0051325 213 98 4,000 4,058E-07 4,882E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 7,414E-07 5,946E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,773E-06 1,066E-03 ! G1 phase GO:0051318 40 19 2,000 3,176E-06 1,528E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 3,402E-06 1,364E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 3,61E-06 1,241E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 3,733E-06 1,123E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,733E-06 9,979E-04 ! negative regulation of transferase activity GO:0051348 140 72 3,000 4,541E-06 1,092E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 5,032E-06 1,101E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 6,599E-06 1,323E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 7,491E-06 1,386E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 9,506E-06 1,634E-03 ! membrane docking GO:0022406 61 30 2,000 1,315E-05 2,11E-03 ! female meiosis GO:0007143 7 5 1,000 2,276E-05 3,422E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 2,276E-05 3,221E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,276E-05 3,042E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 2,276E-05 2,882E-03 ! lymphocyte activation during immune response GO:0002285 9 5 1,000 2,276E-05 2,738E-03 ! virion attachment to host cell surface receptor GO:0019062 15 6 1,000 3,41E-05 3,907E-03 ! T cell mediated immunity GO:0002456 16 6 1,000 3,41E-05 3,729E-03 ! interaction with symbiont GO:0051702 13 6 1,000 3,41E-05 3,567E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 3,41E-05 3,419E-03 ! membrane to membrane docking GO:0022614 14 6 1,000 3,41E-05 3,282E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 3,41E-05 3,156E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 3,41E-05 3,039E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 3,671E-05 3,155E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 3,671E-05 3,046E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 3,943E-05 3,162E-03 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 4,769E-05 3,702E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,769E-05 3,586E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,769E-05 3,477E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,769E-05 3,375E-03 ! vesicle fusion GO:0006906 17 7 1,000 4,769E-05 3,279E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 4,769E-05 3,188E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 4,769E-05 3,101E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 4,834E-05 3,061E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 4,834E-05 2,982E-03 ! protein homooligomerization GO:0051260 76 47 2,000 5,158E-05 3,103E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 6,353E-05 3,728E-03 ! ER overload response GO:0006983 12 8 1,000 6,353E-05 3,639E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 6,353E-05 3,555E-03 ! leukocyte activation during immune response GO:0002366 13 8 1,000 6,353E-05 3,474E-03 GO:0002263|cell activation during immune response, ! response to UV GO:0009411 104 53 2,000 7,404E-05 3,959E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 8,16E-05 4,268E-03 ! gas homeostasis GO:0033483 16 9 1,000 8,16E-05 4,177E-03 ! induction of an organ GO:0001759 14 9 1,000 8,16E-05 4,09E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 8,16E-05 4,007E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 9,209E-05 4,431E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 9,209E-05 4,344E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,019E-04 4,715E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,019E-04 4,626E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,019E-04 4,54E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,019E-04 4,458E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,019E-04 4,378E-03 ! oocyte development GO:0048599 17 10 1,000 1,019E-04 4,301E-03 ! localization within membrane GO:0051668 20 10 1,000 1,019E-04 4,227E-03 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 1,242E-04 5,064E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,244E-04 4,99E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,244E-04 4,908E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,244E-04 4,829E-03 ! oocyte differentiation GO:0009994 18 11 1,000 1,244E-04 4,752E-03 ! developmental induction GO:0031128 19 11 1,000 1,244E-04 4,678E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of cell motion GO:0051272 146 64 2,000 1,302E-04 4,818E-03 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,492E-04 5,438E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,492E-04 5,357E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,492E-04 5,278E-03 ! entry into host cell GO:0030260 32 12 1,000 1,492E-04 5,201E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 1,492E-04 5,127E-03 ! gland morphogenesis GO:0022612 29 12 1,000 1,492E-04 5,055E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,492E-04 4,985E-03 ! negative regulation of cell size GO:0045792 134 69 2,000 1,628E-04 5,366E-03 ! lipid localization GO:0010876 28 13 1,000 1,761E-04 5,726E-03 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 1,761E-04 5,65E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,761E-04 5,576E-03 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 1,761E-04 5,503E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,053E-04 6,332E-03 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,053E-04 6,252E-03 ! protein oligomerization GO:0051259 139 78 2,000 2,341E-04 7,041E-03 ! heterophilic cell adhesion GO:0007157 39 15 1,000 2,366E-04 7,028E-03 ! regulation of vasodilation GO:0042312 26 15 1,000 2,366E-04 6,943E-03 ! regulation of peptidase activity GO:0052547 134 79 2,000 2,431E-04 7,047E-03 ! response to hypoxia GO:0001666 171 81 2,000 2,617E-04 7,497E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 2,702E-04 7,647E-03 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 2,702E-04 7,558E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,702E-04 7,471E-03 ! response to oxygen levels GO:0070482 176 83 2,000 2,813E-04 7,69E-03 ! negative regulation of growth GO:0045926 155 84 2,000 2,914E-04 7,876E-03 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 3,059E-04 8,177E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 3,059E-04 8,087E-03 ! regulation of protein transport GO:0051223 154 87 2,000 3,231E-04 8,449E-03 GO:0070201|regulation of establishment of protein localization, ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 3,438E-04 8,894E-03 ! regulation of cell adhesion GO:0030155 212 89 2,000 3,454E-04 8,841E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 3,839E-04 9,722E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 3,839E-04 9,62E-03 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,261E-04 0,01056883 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 4,261E-04 0,01046099 ! peptidyl-serine modification GO:0018209 43 20 1,000 4,261E-04 0,01035532 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 4,261E-04 0,01025177 ! regulation of protein localization GO:0032880 176 97 2,000 4,446E-04 0,01059183 ! regulation of cell killing GO:0031341 42 21 1,000 4,705E-04 0,01109793 ! inactivation of MAPK activity GO:0000188 39 21 1,000 4,705E-04 0,01099018 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 4,705E-04 0,0108845 ! regulation of vasoconstriction GO:0019229 39 21 1,000 4,705E-04 0,01078084 ! oogenesis GO:0048477 36 21 1,000 4,705E-04 0,01067914 ! cell cycle arrest GO:0007050 213 100 2,000 4,861E-04 0,01092983 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 5,17E-04 0,0115183 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 5,17E-04 0,01141263 ! positive regulation of B cell activation GO:0050871 38 22 1,000 5,17E-04 0,01130888 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,17E-04 0,011207 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 5,657E-04 0,01215291 ! leukocyte adhesion GO:0007159 50 23 1,000 5,657E-04 0,01204536 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 5,657E-04 0,0119397 GO:0010810|regulation of cell-substrate adhesion, ! vesicle targeting GO:0006903 43 23 1,000 5,657E-04 0,01183588 ! vesicle docking GO:0048278 47 24 1,000 6,166E-04 0,01278812 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 6,166E-04 0,01267882 ! membrane depolarization GO:0051899 39 24 1,000 6,166E-04 0,01257137 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 6,166E-04 0,01246573 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 6,695E-04 0,01342373 ! vasculogenesis GO:0001570 46 25 1,000 6,695E-04 0,01331279 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 6,695E-04 0,01320367 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 6,695E-04 0,01309632 ! interaction with host GO:0051701 62 25 1,000 6,695E-04 0,0129907 ! regulation of blood coagulation GO:0030193 40 25 1,000 6,695E-04 0,01288678 ! initiation of viral infection GO:0019059 57 26 1,000 7,246E-04 0,01383642 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 7,246E-04 0,01372747 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 7,246E-04 0,01362022 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 7,246E-04 0,01351464 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 7,246E-04 0,01341068 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 7,246E-04 0,01330831 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 7,818E-04 0,01425023 ! protein amino acid acylation GO:0043543 55 27 1,000 7,818E-04 0,01414308 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 8,411E-04 0,01510266 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 9,026E-04 0,01608557 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 9,026E-04 0,0159673 ! regulation of coagulation GO:0050818 46 29 1,000 9,026E-04 0,01585075 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 9,661E-04 0,0168435 ! regulation of B cell activation GO:0050864 50 30 1,000 9,661E-04 0,01672232 ! cholesterol homeostasis GO:0042632 53 31 1,000 1,032E-03 0,01773066 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 1,000 1,032E-03 0,01760491 ! erythrocyte differentiation GO:0030218 55 31 1,000 1,032E-03 0,01748094 ! cholesterol transport GO:0030301 56 32 1,000 1,099E-03 0,01849795 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,099E-03 0,0183695 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 1,099E-03 0,01824281 ! cell fate specification GO:0001708 52 33 1,000 1,169E-03 0,01926802 ! sterol transport GO:0015918 57 33 1,000 1,169E-03 0,01913695 ! establishment of vesicle localization GO:0051650 61 33 1,000 1,169E-03 0,01900764 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 1,241E-03 0,0200406 ! neutral lipid metabolic process GO:0006638 50 35 1,000 1,315E-03 0,02109298 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 1,315E-03 0,02095329 ! regulation of microtubule-based process GO:0032886 78 35 1,000 1,315E-03 0,02081544 ! vesicle localization GO:0051648 64 35 1,000 1,315E-03 0,02067939 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 1,391E-03 0,02173252 ! tissue remodeling GO:0048771 76 37 1,000 1,469E-03 0,022804 ! glycerol ether metabolic process GO:0006662 53 37 1,000 1,469E-03 0,02265782 ! glycogen metabolic process GO:0005977 61 37 1,000 1,469E-03 0,0225135 ! lipid homeostasis GO:0055088 67 38 1,000 1,549E-03 0,02359093 ! erythrocyte homeostasis GO:0034101 64 38 1,000 1,549E-03 0,02344256 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 1,549E-03 0,02329604 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 1,549E-03 0,02315134 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 1,631E-03 0,02422859 ! organic ether metabolic process GO:0018904 55 39 1,000 1,631E-03 0,02407995 ! gliogenesis GO:0042063 88 41 1,000 1,802E-03 0,02643332 ! female gamete generation GO:0007292 61 41 1,000 1,802E-03 0,02627311 ! energy reserve metabolic process GO:0006112 74 43 1,000 1,98E-03 0,02870239 ! striated muscle cell differentiation GO:0051146 82 43 1,000 1,98E-03 0,02853052 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 2,167E-03 0,03103283 ! leukocyte migration GO:0050900 68 45 1,000 2,167E-03 0,0308492 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 2,167E-03 0,03066774 ! cell growth GO:0016049 84 45 1,000 2,167E-03 0,03048839 ! positive regulation of cell cycle GO:0045787 89 48 1,000 2,462E-03 0,03443593 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 2,462E-03 0,03423688 ! regulation of ossification GO:0030278 117 50 1,000 2,668E-03 0,03689567 ! histone modification GO:0016570 91 50 1,000 2,668E-03 0,03668484 ! viral infectious cycle GO:0019058 99 51 1,000 2,774E-03 0,03792843 ! vesicle organization GO:0016050 107 51 1,000 2,774E-03 0,03771415 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 2,774E-03 0,03750227 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 1,000 2,883E-03 0,03874687 ! membrane fusion GO:0006944 110 52 1,000 2,883E-03 0,03853161 ! covalent chromatin modification GO:0016569 101 52 1,000 2,883E-03 0,03831873 ! cell maturation GO:0048469 100 53 1,000 2,993E-03 0,03956424 ! regulation of protein polymerization GO:0032271 103 53 1,000 2,993E-03 0,03934804 ! activation of phospholipase C activity GO:0007202 103 54 1,000 3,105E-03 0,04059997 GO:0010863|positive regulation of phospholipase C activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 3,219E-03 0,0418637 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 3,219E-03 0,04163862 ! positive regulation of organelle organization GO:0010638 100 56 1,000 3,335E-03 0,04290826 ! regulation of bone remodeling GO:0046850 137 57 1,000 3,453E-03 0,04418917 ! regulation of phospholipase activity GO:0010517 106 57 1,000 3,453E-03 0,04395537 ! regulation of tissue remodeling GO:0034103 140 58 1,000 3,573E-03 0,04524172 ! positive regulation of lipase activity GO:0060193 108 58 1,000 3,573E-03 0,04500485 ! establishment of organelle localization GO:0051656 109 59 1,000 3,694E-03 0,04629646 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 3,818E-03 0,04759859 ! regulation of protein complex assembly GO:0043254 117 61 1,000 3,944E-03 0,04891101 ! viral reproductive process GO:0022415 126 62 1,000 4,071E-03 0,0502335 ! regulation of homeostatic process GO:0032844 134 62 1,000 4,071E-03 0,04997721 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 4,201E-03 0,05130407 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 4,332E-03 0,05264055 ! germ cell development GO:0007281 118 65 1,000 4,465E-03 0,05398644 ! myeloid cell differentiation GO:0030099 111 65 1,000 4,465E-03 0,05371651 ! developmental maturation GO:0021700 116 66 1,000 4,6E-03 0,05506619 ! lung development GO:0030324 144 67 1,000 4,737E-03 0,05642488 ! homeostasis of number of cells GO:0048872 114 67 1,000 4,737E-03 0,05614692 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 4,737E-03 0,05587169 ! adaptive immune response GO:0002250 119 67 1,000 4,737E-03 0,05559915 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 4,876E-03 0,05695072 ! viral reproduction GO:0016032 134 68 1,000 4,876E-03 0,0566756 ! regulation of lipase activity GO:0060191 130 68 1,000 4,876E-03 0,05640312 ! cell cycle checkpoint GO:0000075 137 69 1,000 5,017E-03 0,05775292 ! antigen processing and presentation GO:0019882 104 69 1,000 5,017E-03 0,05747791 ! respiratory tube development GO:0030323 150 70 1,000 5,159E-03 0,05883103 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 5,304E-03 0,06019244 ! regulation of immune effector process GO:0002697 137 71 1,000 5,304E-03 0,05990984 ! regulation of caspase activity GO:0043281 122 72 1,000 5,45E-03 0,06127427 ! respiratory system development GO:0060541 153 72 1,000 5,45E-03 0,06098927 ! meiosis GO:0007126 121 74 1,000 5,748E-03 0,06402672 GO:0051327|M phase of meiotic cell cycle, ! leukocyte mediated immunity GO:0002443 128 74 1,000 5,748E-03 0,06373167 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 5,748E-03 0,06343932 ! organelle localization GO:0051640 136 74 1,000 5,748E-03 0,06314965 ! meiotic cell cycle GO:0051321 122 75 1,000 5,9E-03 0,0645224 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 6,209E-03 0,06759459 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 6,525E-03 0,07071775 ! muscle cell differentiation GO:0042692 159 80 1,000 6,686E-03 0,07213598 ! T cell activation GO:0042110 168 81 1,000 6,849E-03 0,07356084 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 6,849E-03 0,07323391 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of cell activation GO:0050867 145 85 1,000 7,517E-03 0,0800258 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 7,614E-03 0,08070269 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 7,614E-03 0,08034873 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,614E-03 0,07999786 ! positive regulation of helicase activity GO:0051096 11 5 0,000 7,614E-03 0,07965004 ! neuron fate determination GO:0048664 7 5 0,000 7,614E-03 0,07930524 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,614E-03 0,0789634 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 7,614E-03 0,0786245 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 7,614E-03 0,0782885 ! polyol transport GO:0015791 12 5 0,000 7,614E-03 0,07795536 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 7,614E-03 0,07762504 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,614E-03 0,07729751 ! response to superoxide GO:0000303 10 5 0,000 7,614E-03 0,07697273 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,614E-03 0,07665067 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 7,614E-03 0,07633129 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 7,614E-03 0,07601456 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,614E-03 0,07570045 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,614E-03 0,07538893 ! cobalt ion transport GO:0006824 11 5 0,000 7,614E-03 0,07507996 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 7,614E-03 0,07477351 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 7,614E-03 0,07446955 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 7,614E-03 0,07416805 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,614E-03 0,07386899 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,614E-03 0,07357233 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 7,614E-03 0,07327804 ! embryonic camera-type eye development GO:0031076 10 5 0,000 7,614E-03 0,07298609 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,614E-03 0,07269647 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 7,614E-03 0,07240913 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 7,614E-03 0,07212405 ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,614E-03 0,07184121 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 7,614E-03 0,07156058 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 7,614E-03 0,07128214 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 7,614E-03 0,07100585 ! negative chemotaxis GO:0050919 14 5 0,000 7,614E-03 0,0707317 ! positive regulation of histone modification GO:0031058 5 5 0,000 7,614E-03 0,07045965 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,614E-03 0,07018969 ! sensory perception of bitter taste GO:0050913 7 5 0,000 7,614E-03 0,06992179 ! behavioral response to pain GO:0048266 9 5 0,000 7,614E-03 0,06965593 ! clathrin coat assembly GO:0048268 14 5 0,000 7,614E-03 0,06939208 ! Notch receptor processing GO:0007220 8 5 0,000 7,614E-03 0,06913022 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,614E-03 0,06887034 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 7,614E-03 0,0686124 ! micturition GO:0060073 9 5 0,000 7,614E-03 0,06835638 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,614E-03 0,06810227 ! copulation GO:0007620 9 5 0,000 7,614E-03 0,06785004 ! glial cell fate commitment GO:0021781 13 5 0,000 7,614E-03 0,06759967 ! protein maturation by protein folding GO:0022417 13 5 0,000 7,614E-03 0,06735114 ! spermidine metabolic process GO:0008216 7 5 0,000 7,614E-03 0,06710443 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,614E-03 0,06685952 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,614E-03 0,0666164 ! apoptotic cell clearance GO:0043277 20 5 0,000 7,614E-03 0,06637503 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,614E-03 0,06613541 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,614E-03 0,06589752 ! grooming behavior GO:0007625 6 5 0,000 7,614E-03 0,06566132 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,614E-03 0,06542682 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 7,614E-03 0,06519398 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,614E-03 0,0649628 ! response to protozoan GO:0001562 10 5 0,000 7,614E-03 0,06473325 ! positive regulation of glycolysis GO:0045821 14 5 0,000 7,614E-03 0,06450532 ! lymph vessel development GO:0001945 10 5 0,000 7,614E-03 0,06427898 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 7,614E-03 0,06405423 ! endochondral ossification GO:0001958 16 5 0,000 7,614E-03 0,06383104 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,614E-03 0,06360941 ! parathyroid gland development GO:0060017 13 5 0,000 7,614E-03 0,06338931 ! anagen GO:0042640 6 5 0,000 7,614E-03 0,06317072 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,614E-03 0,06295364 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,614E-03 0,06273805 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 7,614E-03 0,06252392 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 7,614E-03 0,06231126 ! dorsal spinal cord development GO:0021516 7 5 0,000 7,614E-03 0,06210003 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 7,614E-03 0,06189023 ! sphingoid catabolic process GO:0046521 6 5 0,000 7,614E-03 0,06168185 ! skeletal myofibril assembly GO:0014866 10 5 0,000 7,614E-03 0,06147486 ! smooth muscle tissue development GO:0048745 28 5 0,000 7,614E-03 0,06126926 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,614E-03 0,06106503 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,614E-03 0,06086216 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,614E-03 0,06066063 ! cardiac muscle fiber development GO:0048739 10 5 0,000 7,614E-03 0,06046043 ! transepithelial chloride transport GO:0030321 9 5 0,000 7,614E-03 0,06026154 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,614E-03 0,06006397 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 7,614E-03 0,05986768 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 7,614E-03 0,05967267 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,614E-03 0,05947893 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,614E-03 0,05928644 ! histidine catabolic process GO:0006548 6 5 0,000 7,614E-03 0,05909519 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 7,614E-03 0,05890518 ! microvillus organization GO:0032528 7 5 0,000 7,614E-03 0,05871638 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 7,614E-03 0,05852878 ! L-serine biosynthetic process GO:0006564 6 5 0,000 7,614E-03 0,05834239 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 7,614E-03 0,05815717 ! tryptophan metabolic process GO:0006568 9 5 0,000 7,614E-03 0,05797313 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 7,614E-03 0,05779025 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 7,614E-03 0,05760852 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 7,614E-03 0,05742793 ! polyol catabolic process GO:0046174 7 5 0,000 7,614E-03 0,05724847 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 7,614E-03 0,05707012 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 7,614E-03 0,05689289 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 7,614E-03 0,05671675 ! muscle cell migration GO:0014812 8 5 0,000 7,614E-03 0,0565417 ! mitochondrial fission GO:0000266 8 5 0,000 7,614E-03 0,05636772 ! sister chromatid cohesion GO:0007062 12 5 0,000 7,614E-03 0,05619481 ! mRNA transcription GO:0009299 9 5 0,000 7,614E-03 0,05602296 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 7,614E-03 0,05585216 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 7,614E-03 0,0556824 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 7,614E-03 0,05551367 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 7,614E-03 0,05534595 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,614E-03 0,05517925 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,614E-03 0,05501354 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,614E-03 0,05484883 ! response to food GO:0032094 6 5 0,000 7,614E-03 0,0546851 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,614E-03 0,05452235 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,614E-03 0,05436056 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 7,614E-03 0,05419973 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,614E-03 0,05403985 ! paraxial mesoderm development GO:0048339 14 5 0,000 7,614E-03 0,05388091 ! forebrain neuron development GO:0021884 13 5 0,000 7,614E-03 0,0537229 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,614E-03 0,05356582 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 7,614E-03 0,05340965 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,614E-03 0,05325439 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,614E-03 0,05310003 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,614E-03 0,05294656 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 7,614E-03 0,05279398 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,614E-03 0,05264227 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 7,614E-03 0,05249143 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 7,614E-03 0,05234146 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 7,614E-03 0,05219233 ! basic amino acid transport GO:0015802 11 5 0,000 7,614E-03 0,05204406 ! cellular glucose homeostasis GO:0001678 5 5 0,000 7,614E-03 0,05189663 ! early endosome to late endosome transport GO:0045022 12 5 0,000 7,614E-03 0,05175003 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,614E-03 0,05160425 ! depyrimidination GO:0045008 10 5 0,000 7,614E-03 0,0514593 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,614E-03 0,05131515 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,614E-03 0,05117181 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,614E-03 0,05102927 ! zinc ion homeostasis GO:0055069 8 5 0,000 7,614E-03 0,05088753 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 7,614E-03 0,05074656 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 7,614E-03 0,05060638 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,614E-03 0,05046697 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,614E-03 0,05032832 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,614E-03 0,05019044 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 7,614E-03 0,0500533 ! peptidyl-arginine modification GO:0018195 9 5 0,000 7,614E-03 0,04991692 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,614E-03 0,04978128 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,614E-03 0,04964637 ! response to arsenic GO:0046685 10 5 0,000 7,614E-03 0,04951219 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 7,614E-03 0,04937873 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,614E-03 0,04924599 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 7,614E-03 0,04911397 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 7,614E-03 0,04898265 ! response to cadmium ion GO:0046686 7 5 0,000 7,614E-03 0,04885203 ! bile acid biosynthetic process GO:0006699 6 5 0,000 7,614E-03 0,0487221 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 7,614E-03 0,04859286 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,614E-03 0,04846431 ! decidualization GO:0046697 11 5 0,000 7,614E-03 0,04833644 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 7,614E-03 0,04820924 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 7,614E-03 0,0480827 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 7,614E-03 0,04795683 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 7,614E-03 0,04783162 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 7,614E-03 0,04770706 ! base conversion or substitution editing GO:0016553 5 5 0,000 7,614E-03 0,04758314 ! neural tube patterning GO:0021532 7 5 0,000 7,614E-03 0,04745987 ! embryonic cleavage GO:0040016 6 5 0,000 7,614E-03 0,04733723 ! peroxisome fission GO:0016559 5 5 0,000 7,614E-03 0,04721523 ! histone demethylation GO:0016577 10 5 0,000 7,614E-03 0,04709385 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 7,614E-03 0,0469731 ! mitotic recombination GO:0006312 9 5 0,000 7,614E-03 0,04685297 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,614E-03 0,04673344 ! metaphase plate congression GO:0051310 7 5 0,000 7,614E-03 0,04661453 ! regulation of sterol transport GO:0032371 7 5 0,000 7,614E-03 0,04649622 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,614E-03 0,04637851 ! enteric nervous system development GO:0048484 8 5 0,000 7,614E-03 0,04626139 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 7,614E-03 0,04614486 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 7,614E-03 0,04602892 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 7,614E-03 0,04591356 ! muscle cell proliferation GO:0033002 11 5 0,000 7,614E-03 0,04579877 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,614E-03 0,04568456 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 7,614E-03 0,04557092 ! plasminogen activation GO:0031639 5 5 0,000 7,614E-03 0,04545784 ! B cell homeostasis GO:0001782 13 5 0,000 7,614E-03 0,04534532 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 7,614E-03 0,04523336 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,614E-03 0,04512194 ! metaphase GO:0051323 8 5 0,000 7,614E-03 0,04501108 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 7,614E-03 0,04490076 ! cellular response to nutrient GO:0031670 8 5 0,000 7,614E-03 0,04479098 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,614E-03 0,04468173 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 7,614E-03 0,04457302 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 7,614E-03 0,04446483 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 7,614E-03 0,04435717 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 7,614E-03 0,04425002 ! response to redox state GO:0051775 5 5 0,000 7,614E-03 0,0441434 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 7,614E-03 0,04403728 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 7,614E-03 0,04393168 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,614E-03 0,04382658 ! regulation of telomerase activity GO:0051972 6 5 0,000 7,614E-03 0,04372198 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,614E-03 0,04361788 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 7,614E-03 0,04351427 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,614E-03 0,04341116 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 7,614E-03 0,04330853 ! striatum development GO:0021756 9 5 0,000 7,614E-03 0,04320639 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 7,614E-03 0,04310473 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 7,614E-03 0,04300354 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,614E-03 0,04290283 ! glial cell migration GO:0008347 11 5 0,000 7,614E-03 0,04280259 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,614E-03 0,04270282 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 7,614E-03 0,04260351 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,614E-03 0,04250466 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,614E-03 0,04240627 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,614E-03 0,04230834 ! neuroprotection GO:0043526 6 5 0,000 7,614E-03 0,04221085 ! neural plate development GO:0001840 8 5 0,000 7,614E-03 0,04211382 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,614E-03 0,04201722 ! regulation of sensory perception GO:0051931 7 5 0,000 7,614E-03 0,04192107 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,614E-03 0,04182536 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,614E-03 0,04173009 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 7,614E-03 0,04163525 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 7,614E-03 0,04154084 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,614E-03 0,04144685 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,614E-03 0,04135329 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 7,614E-03 0,04126016 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,614E-03 0,04116744 ! spindle assembly GO:0051225 6 5 0,000 7,614E-03 0,04107513 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 7,614E-03 0,04098324 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,614E-03 0,04089176 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,614E-03 0,04080069 ! drug metabolic process GO:0017144 6 5 0,000 7,614E-03 0,04071002 ! stem cell division GO:0017145 11 5 0,000 7,614E-03 0,04061976 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,614E-03 0,04052989 ! organ regeneration GO:0031100 7 5 0,000 7,614E-03 0,04044042 ! carnitine metabolic process GO:0009437 7 5 0,000 7,614E-03 0,04035134 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 7,614E-03 0,04026266 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,614E-03 0,04017436 ! gland development GO:0048732 206 88 1,000 8,037E-03 0,04231231 ! ossification GO:0001503 188 90 1,000 8,392E-03 0,04408683 ! bone development GO:0060348 189 91 1,000 8,573E-03 0,0449359 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 8,938E-03 0,04675157 ! regulation of membrane potential GO:0042391 164 93 1,000 8,938E-03 0,04665016 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 8,938E-03 0,04654918 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 9,13E-03 0,04744493 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 9,13E-03 0,04734268 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 9,13E-03 0,04724087 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 9,13E-03 0,04713949 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 9,13E-03 0,04703855 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 9,13E-03 0,04693804 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 9,13E-03 0,04683796 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 9,13E-03 0,0467383 ! sleep GO:0030431 13 6 0,000 9,13E-03 0,04663907 ! response to oxygen radical GO:0000305 11 6 0,000 9,13E-03 0,04654026 ! positive regulation of axon extension GO:0045773 11 6 0,000 9,13E-03 0,04644187 ! myoblast cell fate commitment GO:0048625 16 6 0,000 9,13E-03 0,04634389 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 9,13E-03 0,04624632 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 9,13E-03 0,04614916 ! regulation of interferon-beta production GO:0032648 8 6 0,000 9,13E-03 0,04605242 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 9,13E-03 0,04595607 ! forebrain regionalization GO:0021871 8 6 0,000 9,13E-03 0,04586013 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 9,13E-03 0,04576459 ! male meiosis GO:0007140 7 6 0,000 9,13E-03 0,04566944 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 9,13E-03 0,04557469 ! response to zinc ion GO:0010043 9 6 0,000 9,13E-03 0,04548034 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 9,13E-03 0,04538637 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 9,13E-03 0,04529279 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 9,13E-03 0,04519959 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 9,13E-03 0,04510678 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 9,13E-03 0,04501435 ! malate metabolic process GO:0006108 11 6 0,000 9,13E-03 0,0449223 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 9,13E-03 0,04483062 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 9,13E-03 0,04473931 ! protein refolding GO:0042026 15 6 0,000 9,13E-03 0,04464838 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 9,13E-03 0,04455781 ! opsonization GO:0008228 8 6 0,000 9,13E-03 0,04446762 ! mating behavior GO:0007617 7 6 0,000 9,13E-03 0,04437778 ! neuron remodeling GO:0016322 15 6 0,000 9,13E-03 0,04428831 ! erythrocyte maturation GO:0043249 7 6 0,000 9,13E-03 0,0441992 ! embryonic hemopoiesis GO:0035162 14 6 0,000 9,13E-03 0,04411045 ! equilibrioception GO:0050957 14 6 0,000 9,13E-03 0,04402205 ! protein amino acid dealkylation GO:0008214 12 6 0,000 9,13E-03 0,043934 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 9,13E-03 0,04384631 ! photoreceptor cell development GO:0042461 10 6 0,000 9,13E-03 0,04375897 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 9,13E-03 0,04367197 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 9,13E-03 0,04358532 ! response to interferon-gamma GO:0034341 15 6 0,000 9,13E-03 0,04349901 ! toxin metabolic process GO:0009404 11 6 0,000 9,13E-03 0,04341305 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 9,13E-03 0,04332742 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 9,13E-03 0,04324213 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 9,13E-03 0,04315718 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 9,13E-03 0,04307255 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 9,13E-03 0,04298826 ! cGMP-mediated signaling GO:0019934 13 6 0,000 9,13E-03 0,0429043 ! activation of MAPKKK activity GO:0000185 12 6 0,000 9,13E-03 0,04282067 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 9,13E-03 0,04273736 ! thymic T cell selection GO:0045061 12 6 0,000 9,13E-03 0,04265437 ! protein lipoylation GO:0009249 10 6 0,000 9,13E-03 0,04257171 ! cysteine metabolic process GO:0006534 10 6 0,000 9,13E-03 0,04248937 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 9,13E-03 0,04240734 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 9,13E-03 0,04232563 ! glutamate catabolic process GO:0006538 10 6 0,000 9,13E-03 0,04224424 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 9,13E-03 0,04216315 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 9,13E-03 0,04208238 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 9,13E-03 0,04200192 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 9,13E-03 0,04192176 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 9,13E-03 0,04184191 ! hyperosmotic response GO:0006972 9 6 0,000 9,13E-03 0,04176236 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 9,13E-03 0,04168312 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 9,13E-03 0,04160417 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 9,13E-03 0,04152552 ! urea metabolic process GO:0019627 7 6 0,000 9,13E-03 0,04144717 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 9,13E-03 0,04136912 ! neutrophil activation GO:0042119 8 6 0,000 9,13E-03 0,04129136 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 9,13E-03 0,04121389 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 9,13E-03 0,04113671 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 9,13E-03 0,04105982 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 9,13E-03 0,04098321 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 9,13E-03 0,04090689 ! neuron apoptosis GO:0051402 9 6 0,000 9,13E-03 0,04083086 ! nucleoside salvage GO:0043174 9 6 0,000 9,13E-03 0,04075511 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 9,13E-03 0,04067963 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 9,13E-03 0,04060444 ! negative regulation of platelet activation GO:0010544 9 6 0,000 9,13E-03 0,04052952 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 9,13E-03 0,04045488 ! carnitine transport GO:0015879 10 6 0,000 9,13E-03 0,04038052 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 9,13E-03 0,04030643 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 9,13E-03 0,0402326 ! positive regulation of exocytosis GO:0045921 8 6 0,000 9,13E-03 0,04015905 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 9,13E-03 0,04008577 ! 5S class rRNA transcription GO:0042791 11 6 0,000 9,13E-03 0,04001275 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 9,13E-03 0,03994 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 9,13E-03 0,03986752 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 9,13E-03 0,03979529 ! sodium ion homeostasis GO:0055078 11 6 0,000 9,13E-03 0,03972333 ! establishment of spindle localization GO:0051293 12 6 0,000 9,13E-03 0,03965163 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 9,13E-03 0,03958018 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 9,13E-03 0,039509 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 9,13E-03 0,03943807 ! neural nucleus development GO:0048857 14 6 0,000 9,13E-03 0,03936739 ! response to UV-C GO:0010225 11 6 0,000 9,13E-03 0,03929696 ! astrocyte development GO:0014002 15 6 0,000 9,13E-03 0,03922679 ! protein targeting to lysosome GO:0006622 10 6 0,000 9,13E-03 0,03915687 ! purine base biosynthetic process GO:0009113 17 6 0,000 9,13E-03 0,03908719 ! regulation of dendrite development GO:0050773 16 6 0,000 9,13E-03 0,03901777 ! skeletal muscle contraction GO:0003009 6 6 0,000 9,13E-03 0,03894859 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 9,13E-03 0,03887965 ! response to copper ion GO:0046688 10 6 0,000 9,13E-03 0,03881096 ! response to exogenous dsRNA GO:0043330 10 6 0,000 9,13E-03 0,03874251 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 9,13E-03 0,0386743 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 9,13E-03 0,03860633 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 9,13E-03 0,0385386 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 9,13E-03 0,03847111 ! regulation of dopamine secretion GO:0014059 14 6 0,000 9,13E-03 0,03840385 ! nucleoside catabolic process GO:0009164 7 6 0,000 9,13E-03 0,03833683 ! hair follicle maturation GO:0048820 7 6 0,000 9,13E-03 0,03827004 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 9,13E-03 0,03820348 ! Schwann cell development GO:0014044 15 6 0,000 9,13E-03 0,03813716 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 9,13E-03 0,03807106 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 9,13E-03 0,03800519 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 9,13E-03 0,03793955 ! subpallium development GO:0021544 10 6 0,000 9,13E-03 0,03787414 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 9,13E-03 0,03780895 ! histone ubiquitination GO:0016574 8 6 0,000 9,13E-03 0,03774399 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 9,13E-03 0,03767925 ! maintenance of organ identity GO:0048496 9 6 0,000 9,13E-03 0,03761473 ! G2 phase GO:0051319 16 6 0,000 9,13E-03 0,03755043 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 9,13E-03 0,03748635 ! establishment of planar polarity GO:0001736 7 6 0,000 9,13E-03 0,03742249 ! regulation of mast cell activation GO:0033003 12 6 0,000 9,13E-03 0,03735885 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 9,13E-03 0,03729542 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 9,13E-03 0,03723221 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 9,13E-03 0,03716921 ! receptor internalization GO:0031623 10 6 0,000 9,13E-03 0,03710642 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 9,13E-03 0,03704385 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 9,13E-03 0,03698149 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 9,13E-03 0,03691933 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 9,13E-03 0,03685739 ! protein deubiquitination GO:0016579 14 6 0,000 9,13E-03 0,03679565 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 9,13E-03 0,03673412 ! protein destabilization GO:0031648 9 6 0,000 9,13E-03 0,03667279 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 9,13E-03 0,03661167 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 9,13E-03 0,03655075 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 9,13E-03 0,03649004 ! progesterone metabolic process GO:0042448 10 6 0,000 9,13E-03 0,03642952 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 9,13E-03 0,03636921 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 9,13E-03 0,03630909 ! negative regulation of axon extension GO:0030517 21 6 0,000 9,13E-03 0,03624918 ! removal of superoxide radicals GO:0019430 11 6 0,000 9,13E-03 0,03618946 ! triglyceride catabolic process GO:0019433 10 6 0,000 9,13E-03 0,03612994 ! determination of adult lifespan GO:0008340 15 6 0,000 9,13E-03 0,03607061 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 9,13E-03 0,03601148 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 9,13E-03 0,03595254 ! cerebellar cortex formation GO:0021697 8 6 0,000 9,13E-03 0,03589379 ! catecholamine transport GO:0051937 9 6 0,000 9,13E-03 0,03583524 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 9,13E-03 0,03577688 ! sensory cilium assembly GO:0035058 10 6 0,000 9,13E-03 0,0357187 ! organ or tissue specific immune response GO:0002251 7 6 0,000 9,13E-03 0,03566072 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 9,13E-03 0,03560292 ! maternal placenta development GO:0001893 12 6 0,000 9,13E-03 0,03554531 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 9,13E-03 0,03548789 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 9,13E-03 0,03543065 ! negative regulation of B cell activation GO:0050869 13 6 0,000 9,13E-03 0,03537359 ! protein amino acid prenylation GO:0018346 16 6 0,000 9,13E-03 0,03531672 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 9,13E-03 0,03526004 ! positive regulation of coagulation GO:0050820 12 6 0,000 9,13E-03 0,03520353 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,01007704 0,03879257 GO:0060538|skeletal muscle organ development, ! tRNA transcription GO:0009304 14 7 0,000 0,01064383 0,04090902 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01064383 0,04084377 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01064383 0,04077873 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01064383 0,0407139 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01064383 0,04064928 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01064383 0,04058486 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01064383 0,04052064 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01064383 0,04045663 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01064383 0,04039281 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01064383 0,0403292 ! prostate gland development GO:0030850 13 7 0,000 0,01064383 0,04026579 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01064383 0,04020258 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01064383 0,04013957 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01064383 0,04007675 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01064383 0,04001413 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01064383 0,03995171 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01064383 0,03988948 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01064383 0,03982744 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01064383 0,0397656 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01064383 0,03970394 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01064383 0,03964248 ! glycolipid transport GO:0046836 10 7 0,000 0,01064383 0,03958121 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01064383 0,03952013 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01064383 0,03945924 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01064383 0,03939853 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01064383 0,03933801 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01064383 0,03927767 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01064383 0,03921753 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01064383 0,03915756 ! mRNA stabilization GO:0048255 18 7 0,000 0,01064383 0,03909778 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01064383 0,03903818 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01064383 0,03897876 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01064383 0,03891952 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01064383 0,03886046 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01064383 0,03880158 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01064383 0,03874288 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01064383 0,03868436 ! lipoprotein transport GO:0042953 14 7 0,000 0,01064383 0,03862601 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01064383 0,03856784 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01064383 0,03850984 ! rhythmic behavior GO:0007622 15 7 0,000 0,01064383 0,03845202 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01064383 0,03839437 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01064383 0,03833689 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01064383 0,03827959 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01064383 0,03822245 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01064383 0,03816549 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01064383 0,0381087 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01064383 0,03805207 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01064383 0,03799561 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01064383 0,03793932 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01064383 0,0378832 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01064383 0,03782724 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01064383 0,03777145 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01064383 0,03771582 ! spinal cord patterning GO:0021511 13 7 0,000 0,01064383 0,03766036 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01064383 0,03760506 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01064383 0,03754992 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01064383 0,03749494 ! adrenal gland development GO:0030325 17 7 0,000 0,01064383 0,03744012 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01064383 0,03738547 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01064383 0,03733097 ! ovulation GO:0030728 9 7 0,000 0,01064383 0,03727663 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01064383 0,03722245 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01064383 0,03716842 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01064383 0,03711456 ! microtubule nucleation GO:0007020 20 7 0,000 0,01064383 0,03706085 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01064383 0,03700729 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01064383 0,03695389 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01064383 0,03690064 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01064383 0,03684755 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01064383 0,0367946 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01064383 0,03674181 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01064383 0,03668917 ! galactose metabolic process GO:0006012 13 7 0,000 0,01064383 0,03663669 ! response to dietary excess GO:0002021 8 7 0,000 0,01064383 0,03658435 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01064383 0,03653216 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01064383 0,03648012 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01064383 0,03642823 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01064383 0,03637648 ! organ growth GO:0035265 15 7 0,000 0,01064383 0,03632489 ! purine salvage GO:0043101 10 7 0,000 0,01064383 0,03627343 ! nucleoside transport GO:0015858 8 7 0,000 0,01064383 0,03622213 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01064383 0,03617097 ! parturition GO:0007567 14 7 0,000 0,01064383 0,03611995 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01064383 0,03606908 ! rRNA modification GO:0000154 14 7 0,000 0,01064383 0,03601835 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01064383 0,03596776 ! spindle checkpoint GO:0031577 15 7 0,000 0,01064383 0,03591731 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01064383 0,03586701 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01064383 0,03581684 ! macrophage differentiation GO:0030225 11 7 0,000 0,01064383 0,03576682 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01064383 0,03571694 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01064383 0,03566719 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01064383 0,03561759 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01064383 0,03556812 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01064383 0,03551879 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01064383 0,03546959 ! fibrinolysis GO:0042730 10 7 0,000 0,01064383 0,03542053 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01064383 0,03537161 ! eating behavior GO:0042755 7 7 0,000 0,01064383 0,03532282 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01064383 0,03527417 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01064383 0,03522565 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01064383 0,03517726 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01064383 0,035129 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01064383 0,03508088 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01064383 0,03503289 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01064383 0,03498503 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01064383 0,0349373 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01064383 0,03488971 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01064383 0,03484224 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01064383 0,0347949 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01064383 0,03474769 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01064383 0,0347006 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01064383 0,03465365 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01064383 0,03460682 ! regulation of meiosis GO:0040020 12 7 0,000 0,01064383 0,03456011 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01064383 0,03451354 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01064383 0,03446708 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01064383 0,03442076 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01064383 0,03437456 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01064383 0,03432848 ! transcription termination GO:0006353 13 7 0,000 0,01064383 0,03428252 ! response to tumor cell GO:0002347 13 7 0,000 0,01064383 0,03423669 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01064383 0,03419098 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01064383 0,03414539 ! anaphase GO:0051322 17 7 0,000 0,01064383 0,03409993 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01064383 0,03405458 ! axonal fasciculation GO:0007413 18 7 0,000 0,01064383 0,03400935 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01064383 0,03396425 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01064383 0,03391926 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01064383 0,0338744 ! diuresis GO:0030146 12 7 0,000 0,01064383 0,03382965 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01064383 0,03378502 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01064383 0,03374051 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01064383 0,03369611 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01064383 0,03365183 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01064383 0,03360767 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01064383 0,03356362 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01064383 0,03351969 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01064383 0,03347587 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01064383 0,03343217 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01064383 0,03338858 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01064383 0,03334511 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01064383 0,03330175 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01064383 0,0332585 ! lymph node development GO:0048535 10 7 0,000 0,01064383 0,03321536 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01064383 0,03317234 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01064383 0,03312942 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01064383 0,03308662 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01064383 0,03304393 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01064383 0,03300135 ! adult feeding behavior GO:0008343 9 7 0,000 0,01064383 0,03295887 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01064383 0,03291651 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01064383 0,03287425 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01064383 0,03283211 ! muscle adaptation GO:0043500 14 7 0,000 0,01064383 0,03279007 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01064383 0,03274814 ! retina homeostasis GO:0001895 12 7 0,000 0,01064383 0,03270631 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01064383 0,0326646 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01064383 0,03262299 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01064383 0,03258148 ! protein prenylation GO:0018342 18 7 0,000 0,01064383 0,03254008 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01064383 0,03249879 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0121553 0,03706672 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0121553 0,0370198 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0121553 0,036973 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0121553 0,03692632 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0121553 0,03687975 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0121553 0,0368333 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0121553 0,03678697 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0121553 0,03674076 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0121553 0,03669466 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0121553 0,03664867 ! meiotic prophase I GO:0007128 13 8 0,000 0,0121553 0,03660281 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0121553 0,03655705 ! oligopeptide transport GO:0006857 15 8 0,000 0,0121553 0,03651141 ! UTP metabolic process GO:0046051 8 8 0,000 0,0121553 0,03646589 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0121553 0,03642048 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0121553 0,03637518 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0121553 0,03632999 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0121553 0,03628492 ! succinate metabolic process GO:0006105 14 8 0,000 0,0121553 0,03623995 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0121553 0,0361951 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0121553 0,03615036 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0121553 0,03610573 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0121553 0,03606121 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0121553 0,0360168 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0121553 0,0359725 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0121553 0,03592831 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0121553 0,03588422 ! reflex GO:0060004 16 8 0,000 0,0121553 0,03584025 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0121553 0,03579638 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0121553 0,03575262 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0121553 0,03570897 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0121553 0,03566542 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0121553 0,03562198 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0121553 0,03557864 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0121553 0,03553541 ! pigment granule organization GO:0048753 16 8 0,000 0,0121553 0,03549228 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0121553 0,03544926 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0121553 0,03540635 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0121553 0,03536353 ! histidine metabolic process GO:0006547 16 8 0,000 0,0121553 0,03532082 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0121553 0,03527822 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0121553 0,03523571 ! glycine catabolic process GO:0006546 13 8 0,000 0,0121553 0,03519331 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0121553 0,03515101 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0121553 0,03510881 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0121553 0,03506672 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0121553 0,03502472 ! melanin metabolic process GO:0006582 15 8 0,000 0,0121553 0,03498283 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0121553 0,03494103 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0121553 0,03489933 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0121553 0,03485774 ! macrophage activation GO:0042116 12 8 0,000 0,0121553 0,03481624 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0121553 0,03477484 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0121553 0,03473354 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0121553 0,03469234 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0121553 0,03465124 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0121553 0,03461023 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0121553 0,03456932 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0121553 0,0345285 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0121553 0,03448779 ! osteoblast development GO:0002076 16 8 0,000 0,0121553 0,03444716 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0121553 0,03440664 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0121553 0,03436621 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0121553 0,03432587 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0121553 0,03428563 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0121553 0,03424548 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0121553 0,03420543 ! response to UV-B GO:0010224 16 8 0,000 0,0121553 0,03416547 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0121553 0,0341256 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0121553 0,03408583 ! intermediate filament organization GO:0045109 12 8 0,000 0,0121553 0,03404615 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0121553 0,03400656 ! cellular extravasation GO:0045123 12 8 0,000 0,0121553 0,03396706 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0121553 0,03392766 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0121553 0,03388835 ! response to antibiotic GO:0046677 11 8 0,000 0,0121553 0,03384912 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0121553 0,03380999 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0121553 0,03377095 ! DNA topological change GO:0006265 12 8 0,000 0,0121553 0,033732 ! response to tropane GO:0014073 15 8 0,000 0,0121553 0,03369314 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0121553 0,03365436 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0121553 0,03361568 ! melanosome transport GO:0032402 13 8 0,000 0,0121553 0,03357709 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,0121553 0,03353858 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0121553 0,03350016 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0121553 0,03346183 ! mast cell activation GO:0045576 14 8 0,000 0,0121553 0,03342359 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0121553 0,03338544 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0121553 0,03334737 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0121553 0,03330939 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0121553 0,03327149 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0121553 0,03323368 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0121553 0,03319596 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0121553 0,03315832 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0121553 0,03312077 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0121553 0,03308331 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0121553 0,03304592 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0121553 0,03300863 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0121553 0,03297141 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0121553 0,03293428 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0121553 0,03289724 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0121553 0,03286027 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0121553 0,03282339 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0121553 0,03278659 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0121553 0,03274988 ! hormone catabolic process GO:0042447 17 8 0,000 0,0121553 0,03271325 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0121553 0,0326767 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0121553 0,03264023 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0121553 0,03260384 ! ATP catabolic process GO:0006200 11 8 0,000 0,0121553 0,03256753 ! blastocyst growth GO:0001832 19 8 0,000 0,0121553 0,0325313 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0121553 0,03249516 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0121553 0,03245909 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0121553 0,03242311 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0121553 0,0323872 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0121553 0,03235137 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0121553 0,03231563 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0121553 0,03227996 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0121553 0,03224437 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0121553 0,03220886 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0121553 0,03217342 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0121553 0,03213807 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0121553 0,03210279 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0121553 0,03206759 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0121553 0,03203247 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0121553 0,03199742 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0121553 0,03196245 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0121553 0,03192756 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01366451 0,03585257 ! axon extension GO:0048675 15 9 0,000 0,01366451 0,03581351 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01366451 0,03577454 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01366451 0,03573566 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01366451 0,03569686 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01366451 0,03565814 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01366451 0,03561951 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01366451 0,03558096 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01366451 0,03554249 ! phosphate transport GO:0006817 19 9 0,000 0,01366451 0,03550411 ! reproductive behavior GO:0019098 19 9 0,000 0,01366451 0,03546581 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01366451 0,03542759 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01366451 0,03538946 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01366451 0,0353514 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01366451 0,03531343 ! GTP metabolic process GO:0046039 9 9 0,000 0,01366451 0,03527554 ! RNA methylation GO:0001510 15 9 0,000 0,01366451 0,03523773 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01366451 0,03520001 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01366451 0,03516236 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01366451 0,03512479 ! artery development GO:0060840 24 9 0,000 0,01366451 0,03508731 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01366451 0,0350499 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01366451 0,03501257 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01366451 0,03497533 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01366451 0,03493816 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01366451 0,03490107 ! chemosensory behavior GO:0007635 20 9 0,000 0,01366451 0,03486406 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01366451 0,03482713 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01366451 0,03479027 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01366451 0,03475349 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01366451 0,0347168 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01366451 0,03468018 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01366451 0,03464363 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01366451 0,03460716 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01366451 0,03457077 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01366451 0,03453446 ! protein targeting to ER GO:0045047 22 9 0,000 0,01366451 0,03449822 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01366451 0,03446206 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01366451 0,03442597 ! T cell selection GO:0045058 23 9 0,000 0,01366451 0,03438996 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,01366451 0,03435403 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01366451 0,03431817 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01366451 0,03428238 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01366451 0,03424667 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01366451 0,03421104 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01366451 0,03417547 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01366451 0,03413999 ! mannose metabolic process GO:0006013 13 9 0,000 0,01366451 0,03410457 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01366451 0,03406923 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01366451 0,03403396 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01366451 0,03399877 ! receptor clustering GO:0043113 18 9 0,000 0,01366451 0,03396364 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01366451 0,03392859 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01366451 0,03389361 ! ruffle organization GO:0031529 15 9 0,000 0,01366451 0,03385871 ! retinol metabolic process GO:0042572 18 9 0,000 0,01366451 0,03382387 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01366451 0,03378911 ! behavioral fear response GO:0001662 22 9 0,000 0,01366451 0,03375442 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01366451 0,0337198 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01366451 0,03368525 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01366451 0,03365077 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01366451 0,03361637 ! protein heterooligomerization GO:0051291 16 9 0,000 0,01366451 0,03358203 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01366451 0,03354776 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01366451 0,03351356 ! segment specification GO:0007379 13 9 0,000 0,01366451 0,03347944 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01366451 0,03344538 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01366451 0,03341139 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01366451 0,03337747 ! response to amine stimulus GO:0014075 13 9 0,000 0,01366451 0,03334362 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01366451 0,03330983 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01366451 0,03327612 ! erythrocyte development GO:0048821 15 9 0,000 0,01366451 0,03324247 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01366451 0,0332089 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01366451 0,03317538 ! renal water homeostasis GO:0003091 14 9 0,000 0,01366451 0,03314194 ! postreplication repair GO:0006301 22 9 0,000 0,01366451 0,03310857 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01366451 0,03307526 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01366451 0,03304202 ! icosanoid secretion GO:0032309 15 9 0,000 0,01366451 0,03300884 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01366451 0,03297573 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01366451 0,03294269 ! regulation of cell division GO:0051302 15 9 0,000 0,01366451 0,03290972 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01366451 0,03287681 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01366451 0,03284396 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01366451 0,03281118 ! sterol catabolic process GO:0016127 11 9 0,000 0,01366451 0,03277847 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01366451 0,03274582 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01366451 0,03271324 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01366451 0,03268072 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01366451 0,03264827 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01366451 0,03261588 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01366451 0,03258355 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01366451 0,03255129 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01366451 0,0325191 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01366451 0,03248696 ! purine base metabolic process GO:0006144 21 9 0,000 0,01366451 0,03245489 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01366451 0,03242289 ! pigment granule transport GO:0051904 17 9 0,000 0,01366451 0,03239094 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01366451 0,03235906 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01366451 0,03232724 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01366451 0,03229549 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01366451 0,03226379 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01366451 0,03223216 ! mitochondrion localization GO:0051646 15 9 0,000 0,01366451 0,03220059 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,01517146 0,03571677 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01517146 0,03568186 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,01517146 0,03564701 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01517146 0,03561224 ! synapsis GO:0007129 13 10 0,000 0,01517146 0,03557753 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,01517146 0,03554288 ! N-glycan processing GO:0006491 20 10 0,000 0,01517146 0,03550831 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,01517146 0,0354738 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,01517146 0,03543936 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01517146 0,03540499 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,01517146 0,03537068 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,01517146 0,03533644 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,01517146 0,03530227 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,01517146 0,03526816 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,01517146 0,03523411 ! androgen metabolic process GO:0008209 17 10 0,000 0,01517146 0,03520014 ! phospholipid efflux GO:0033700 16 10 0,000 0,01517146 0,03516623 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01517146 0,03513238 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,01517146 0,0350986 ! lung alveolus development GO:0048286 26 10 0,000 0,01517146 0,03506488 ! pathogenesis GO:0009405 13 10 0,000 0,01517146 0,03503123 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01517146 0,03499764 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,01517146 0,03496412 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,01517146 0,03493066 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,01517146 0,03489727 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,01517146 0,03486394 ! endoderm development GO:0007492 16 10 0,000 0,01517146 0,03483067 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,01517146 0,03479747 ! arginine catabolic process GO:0006527 13 10 0,000 0,01517146 0,03476433 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01517146 0,03473125 ! proline metabolic process GO:0006560 13 10 0,000 0,01517146 0,03469823 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01517146 0,03466528 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,01517146 0,03463239 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,01517146 0,03459957 ! V(D)J recombination GO:0033151 28 10 0,000 0,01517146 0,0345668 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,01517146 0,0345341 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,01517146 0,03450146 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,01517146 0,03446888 ! B cell proliferation GO:0042100 18 10 0,000 0,01517146 0,03443636 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,01517146 0,0344039 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,01517146 0,03437151 ! multicellular organism growth GO:0035264 18 10 0,000 0,01517146 0,03433917 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,01517146 0,0343069 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,01517146 0,03427469 ! epithelial cell development GO:0002064 20 10 0,000 0,01517146 0,03424254 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,01517146 0,03421044 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01517146 0,03417841 ! macroautophagy GO:0016236 17 10 0,000 0,01517146 0,03414644 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,01517146 0,03411453 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,01517146 0,03408267 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,01517146 0,03405088 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,01517146 0,03401914 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,01517146 0,03398747 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01517146 0,03395585 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01517146 0,0339243 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01517146 0,0338928 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01517146 0,03386136 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,01517146 0,03382997 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,01517146 0,03379865 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,01517146 0,03376738 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,01517146 0,03373618 ! blastoderm segmentation GO:0007350 18 10 0,000 0,01517146 0,03370503 ! response to dsRNA GO:0043331 20 10 0,000 0,01517146 0,03367393 ! DNA ligation GO:0006266 19 10 0,000 0,01517146 0,0336429 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,01517146 0,03361192 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01517146 0,033581 ! melanosome localization GO:0032400 16 10 0,000 0,01517146 0,03355013 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,01517146 0,03351932 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,01517146 0,03348857 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,01517146 0,03345788 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01517146 0,03342724 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,01517146 0,03339665 ! mRNA cleavage GO:0006379 17 10 0,000 0,01517146 0,03336613 ! protein sumoylation GO:0016925 15 10 0,000 0,01517146 0,03333566 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01517146 0,03330524 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01517146 0,03327488 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,01517146 0,03324457 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,01517146 0,03321432 ! salivary gland development GO:0007431 27 10 0,000 0,01517146 0,03318413 ! prophase GO:0051324 15 10 0,000 0,01517146 0,03315399 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,01517146 0,0331239 ! apical protein localization GO:0045176 15 10 0,000 0,01517146 0,03309387 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,01517146 0,0330639 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,01517146 0,03303397 ! midbrain development GO:0030901 13 10 0,000 0,01517146 0,03300411 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,01517146 0,03297429 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,01517146 0,03294453 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,01517146 0,03291483 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,01517146 0,03288517 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01517146 0,03285557 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01517146 0,03282603 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,01517146 0,03279653 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,01517146 0,03276709 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,01517146 0,03273771 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01517146 0,03270837 ! blastocyst formation GO:0001825 17 10 0,000 0,01517146 0,03267909 ! cerebellar cortex development GO:0021695 15 10 0,000 0,01517146 0,03264986 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,01517146 0,03262068 ! activation of innate immune response GO:0002218 12 10 0,000 0,01517146 0,03259156 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,01517146 0,03256248 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,01517146 0,03253346 ! response to nicotine GO:0035094 20 10 0,000 0,01517146 0,03250449 ! establishment of cell polarity GO:0030010 16 10 0,000 0,01517146 0,03247557 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,01517146 0,0324467 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01517146 0,03241789 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,01667617 0,03560147 ! respiratory burst GO:0045730 17 11 0,000 0,01667617 0,03556991 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,01667617 0,03553841 ! neuron fate specification GO:0048665 17 11 0,000 0,01667617 0,03550696 ! telencephalon cell migration GO:0022029 20 11 0,000 0,01667617 0,03547556 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,01667617 0,03544422 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,01667617 0,03541294 ! thyroid gland development GO:0030878 26 11 0,000 0,01667617 0,03538171 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,01667617 0,03535054 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,01667617 0,03531942 ! response to pain GO:0048265 24 11 0,000 0,01667617 0,03528835 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01667617 0,03525735 ! T cell proliferation GO:0042098 26 11 0,000 0,01667617 0,03522639 ! blood vessel remodeling GO:0001974 29 11 0,000 0,01667617 0,03519549 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,01667617 0,03516464 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,01667617 0,03513385 ! bone resorption GO:0045453 16 11 0,000 0,01667617 0,03510311 ! ventral spinal cord development GO:0021517 21 11 0,000 0,01667617 0,03507243 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01667617 0,0350418 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01667617 0,03501122 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,01667617 0,0349807 ! melanocyte differentiation GO:0030318 21 11 0,000 0,01667617 0,03495023 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,01667617 0,03491981 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,01667617 0,03488944 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,01667617 0,03485913 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,01667617 0,03482887 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,01667617 0,03479866 ! lipid digestion GO:0044241 18 11 0,000 0,01667617 0,03476851 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,01667617 0,03473841 ! UV protection GO:0009650 19 11 0,000 0,01667617 0,03470836 ! adult heart development GO:0007512 14 11 0,000 0,01667617 0,03467836 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,01667617 0,03464841 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01667617 0,03461852 ! temperature homeostasis GO:0001659 17 11 0,000 0,01667617 0,03458867 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,01667617 0,03455888 ! negative regulation of ossification GO:0030279 26 11 0,000 0,01667617 0,03452914 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,01667617 0,03449945 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,01667617 0,03446981 ! regulation of organ growth GO:0046620 13 11 0,000 0,01667617 0,03444022 ! pigment granule localization GO:0051875 20 11 0,000 0,01667617 0,03441069 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,01667617 0,0343812 ! vasoconstriction GO:0042310 18 11 0,000 0,01667617 0,03435176 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01667617 0,03432238 ! embryonic axis specification GO:0000578 18 11 0,000 0,01667617 0,03429304 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,01667617 0,03426376 ! snRNA metabolic process GO:0016073 24 11 0,000 0,01667617 0,03423452 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01667617 0,03420534 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,01667617 0,0341762 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01667617 0,03414711 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,01667617 0,03411808 ! zymogen activation GO:0031638 15 11 0,000 0,01667617 0,03408909 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,01667617 0,03406015 ! neuroblast proliferation GO:0007405 24 11 0,000 0,01667617 0,03403126 ! nucleosome positioning GO:0016584 15 11 0,000 0,01667617 0,03400242 ! regulation of isotype switching GO:0045191 22 11 0,000 0,01667617 0,03397363 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,01667617 0,03394489 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,01667617 0,0339162 ! acid secretion GO:0046717 18 11 0,000 0,01667617 0,03388755 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01667617 0,03385895 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,01667617 0,0338304 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,01667617 0,0338019 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,01667617 0,03377345 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,01667617 0,03374505 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,01667617 0,03371669 ! cholesterol efflux GO:0033344 19 11 0,000 0,01667617 0,03368838 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,01667617 0,03366012 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01667617 0,0336319 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,01667617 0,03360373 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,01667617 0,03357561 ! embryonic gut development GO:0048566 15 11 0,000 0,01667617 0,03354754 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,01667617 0,03351951 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,01667617 0,03349154 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,01667617 0,0334636 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,01667617 0,03343572 ! defense response to fungus GO:0050832 13 11 0,000 0,01667617 0,03340788 ! lysogeny GO:0030069 21 11 0,000 0,01667617 0,03338008 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01667617 0,03335234 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,01667617 0,03332463 ! sequestering of metal ion GO:0051238 14 11 0,000 0,01667617 0,03329698 ! lamellipodium assembly GO:0030032 20 11 0,000 0,01667617 0,03326937 ! regulation of embryonic development GO:0045995 27 11 0,000 0,01667617 0,03324181 ! nucleus localization GO:0051647 19 11 0,000 0,01667617 0,03321429 ! regulation of synapse organization GO:0050807 17 11 0,000 0,01667617 0,03318681 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,01817862 0,03614691 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,01817862 0,03611706 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,01817862 0,03608726 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,01817862 0,03605751 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,01817862 0,03602781 ! virus-host interaction GO:0019048 29 12 0,000 0,01817862 0,03599816 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,01817862 0,03596856 ! cartilage condensation GO:0001502 20 12 0,000 0,01817862 0,035939 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,01817862 0,0359095 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01817862 0,03588004 ! protein complex disassembly GO:0043241 27 12 0,000 0,01817862 0,03585063 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01817862 0,03582127 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,01817862 0,03579195 ! hippocampus development GO:0021766 26 12 0,000 0,01817862 0,03576269 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,01817862 0,03573347 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01817862 0,0357043 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,01817862 0,03567518 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,01817862 0,0356461 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,01817862 0,03561707 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,01817862 0,03558809 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,01817862 0,03555916 ! drug transport GO:0015893 16 12 0,000 0,01817862 0,03553027 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,01817862 0,03550143 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,01817862 0,03547264 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,01817862 0,03544389 ! polyamine metabolic process GO:0006595 17 12 0,000 0,01817862 0,03541519 ! focal adhesion formation GO:0048041 35 12 0,000 0,01817862 0,03538654 ! mitotic spindle organization GO:0007052 21 12 0,000 0,01817862 0,03535793 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,01817862 0,03532937 ! forebrain cell migration GO:0021885 21 12 0,000 0,01817862 0,03530086 ! asymmetric protein localization GO:0008105 20 12 0,000 0,01817862 0,03527239 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,01817862 0,03524397 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,01817862 0,03521559 ! fear response GO:0042596 26 12 0,000 0,01817862 0,03518726 ! monoamine transport GO:0015844 18 12 0,000 0,01817862 0,03515898 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01817862 0,03513073 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,01817862 0,03510254 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,01817862 0,03507439 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,01817862 0,03504629 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01817862 0,03501823 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,01817862 0,03499021 ! protein homotetramerization GO:0051289 21 12 0,000 0,01817862 0,03496224 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,01817862 0,03493432 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,01817862 0,03490644 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,01817862 0,0348786 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,01817862 0,03485081 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,01817862 0,03482306 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01817862 0,03479536 ! cranial nerve development GO:0021545 20 12 0,000 0,01817862 0,0347677 ! fucose catabolic process GO:0019317 22 12 0,000 0,01817862 0,03474008 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,01817862 0,03471251 ! histone methylation GO:0016571 26 12 0,000 0,01817862 0,03468498 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,01817862 0,0346575 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01817862 0,03463006 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,01817862 0,03460266 ! T cell homeostasis GO:0043029 25 12 0,000 0,01817862 0,03457531 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,01817862 0,034548 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,01817862 0,03452073 ! spleen development GO:0048536 22 12 0,000 0,01817862 0,03449351 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,01817862 0,03446632 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,01817862 0,03443918 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,01817862 0,03441209 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,01817862 0,03438504 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,01817862 0,03435802 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,01817862 0,03433106 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,01817862 0,03430413 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,01817862 0,03427725 ! response to cold GO:0009409 17 12 0,000 0,01817862 0,0342504 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,01817862 0,0342236 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,01817862 0,03419685 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01967883 0,03699005 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,01967883 0,03696118 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01967883 0,03693235 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01967883 0,03690356 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,01967883 0,03687482 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,01967883 0,03684612 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,01967883 0,03681747 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,01967883 0,03678886 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,01967883 0,0367603 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,01967883 0,03673178 ! endocrine pancreas development GO:0031018 22 13 0,000 0,01967883 0,03670331 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,01967883 0,03667488 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,01967883 0,03664649 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,01967883 0,03661815 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01967883 0,03658985 ! methionine metabolic process GO:0006555 27 13 0,000 0,01967883 0,0365616 ! plasma membrane organization GO:0007009 24 13 0,000 0,01967883 0,03653339 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,01967883 0,03650522 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,01967883 0,03647709 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,01967883 0,03644901 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,01967883 0,03642097 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,01967883 0,03639298 ! response to X-ray GO:0010165 25 13 0,000 0,01967883 0,03636503 ! cytokine metabolic process GO:0042107 22 13 0,000 0,01967883 0,03633712 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,01967883 0,03630925 ! exocrine system development GO:0035272 32 13 0,000 0,01967883 0,03628143 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,01967883 0,03625365 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,01967883 0,03622591 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,01967883 0,03619822 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,01967883 0,03617056 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,01967883 0,03614295 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,01967883 0,03611538 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,01967883 0,03608786 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,01967883 0,03606037 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,01967883 0,03603293 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,01967883 0,03600553 ! regulation of cellular pH GO:0030641 22 13 0,000 0,01967883 0,03597817 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01967883 0,03595085 ! ribosome assembly GO:0042255 17 13 0,000 0,01967883 0,03592357 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,01967883 0,03589634 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,01967883 0,03586914 ! chromatin silencing GO:0006342 26 13 0,000 0,01967883 0,03584199 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,01967883 0,03581488 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01967883 0,03578781 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,01967883 0,03576078 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,01967883 0,03573379 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,01967883 0,03570684 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,01967883 0,03567993 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01967883 0,03565306 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,01967883 0,03562624 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,01967883 0,03559945 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,01967883 0,0355727 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,01967883 0,035546 ! embryonic placenta development GO:0001892 23 13 0,000 0,01967883 0,03551933 ! insulin secretion GO:0030073 23 13 0,000 0,01967883 0,0354927 ! actin filament polymerization GO:0030041 24 13 0,000 0,01967883 0,03546612 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,01967883 0,03543957 ! acrosome reaction GO:0007340 18 13 0,000 0,01967883 0,03541306 ! rRNA transcription GO:0009303 25 14 0,000 0,0211768 0,03808025 ! lactation GO:0007595 26 14 0,000 0,0211768 0,03805181 ! reproductive cellular process GO:0048610 20 14 0,000 0,0211768 0,03802341 ! tRNA modification GO:0006400 20 14 0,000 0,0211768 0,03799506 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0211768 0,03796675 ! regulation of S phase GO:0033261 23 14 0,000 0,0211768 0,03793848 ! water transport GO:0006833 21 14 0,000 0,0211768 0,03791025 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0211768 0,03788206 ! non-recombinational repair GO:0000726 25 14 0,000 0,0211768 0,03785392 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0211768 0,03782582 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0211768 0,03779775 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0211768 0,03776974 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0211768 0,03774176 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0211768 0,03771382 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0211768 0,03768593 ! palate development GO:0060021 31 14 0,000 0,0211768 0,03765807 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0211768 0,03763026 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0211768 0,03760249 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0211768 0,03757476 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0211768 0,03754707 ! arginine metabolic process GO:0006525 17 14 0,000 0,0211768 0,03751942 ! regulation of heart rate GO:0002027 24 14 0,000 0,0211768 0,03749181 ! organic alcohol transport GO:0015850 29 14 0,000 0,0211768 0,03746425 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0211768 0,03743672 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0211768 0,03740923 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0211768 0,03738179 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0211768 0,03735438 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0211768 0,03732701 ! L-amino acid transport GO:0015807 30 14 0,000 0,0211768 0,03729969 ! bone mineralization GO:0030282 17 14 0,000 0,0211768 0,0372724 ! stem cell development GO:0048864 43 14 0,000 0,0211768 0,03724516 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0211768 0,03721795 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0211768 0,03719078 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0211768 0,03716366 ! cerebellum development GO:0021549 21 14 0,000 0,0211768 0,03713657 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0211768 0,03710952 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0211768 0,03708251 ! response to gamma radiation GO:0010332 28 14 0,000 0,0211768 0,03705554 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0211768 0,03702861 ! cofactor transport GO:0051181 26 14 0,000 0,0211768 0,03700172 ! NADP metabolic process GO:0006739 24 14 0,000 0,0211768 0,03697487 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0211768 0,03694806 ! intestinal absorption GO:0050892 25 14 0,000 0,0211768 0,03692129 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0211768 0,03689455 ! oxygen transport GO:0015671 21 14 0,000 0,0211768 0,03686785 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0211768 0,0368412 ! male genitalia development GO:0030539 24 14 0,000 0,0211768 0,03681458 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0211768 0,036788 ! regulation of axon extension GO:0030516 37 14 0,000 0,0211768 0,03676145 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,0211768 0,03673495 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0211768 0,03670848 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02267252 0,03927292 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02267252 0,03924467 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02267252 0,03921646 ! superoxide anion generation GO:0042554 20 15 0,000 0,02267252 0,03918828 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02267252 0,03916015 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02267252 0,03913206 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02267252 0,03910401 ! copper ion transport GO:0006825 20 15 0,000 0,02267252 0,039076 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02267252 0,03904803 ! sulfate transport GO:0008272 23 15 0,000 0,02267252 0,03902009 ! response to cAMP GO:0051591 22 15 0,000 0,02267252 0,0389922 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02267252 0,03896435 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02267252 0,03893654 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02267252 0,03890877 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02267252 0,03888104 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02267252 0,03885334 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02267252 0,03882569 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02267252 0,03879807 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02267252 0,0387705 ! pituitary gland development GO:0021983 29 15 0,000 0,02267252 0,03874296 ! vesicle coating GO:0006901 33 15 0,000 0,02267252 0,03871547 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02267252 0,03868801 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02267252 0,03866059 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02267252 0,03863321 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02267252 0,03860587 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02267252 0,03857857 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02267252 0,0385513 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02267252 0,03852408 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02267252 0,03849689 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02267252 0,03846974 ! histone deacetylation GO:0016575 20 15 0,000 0,02267252 0,03844263 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02267252 0,03841556 ! tissue regeneration GO:0042246 26 15 0,000 0,02267252 0,03838852 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02267252 0,03836153 ! water homeostasis GO:0030104 27 15 0,000 0,02267252 0,03833457 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02267252 0,03830765 ! muscle maintenance GO:0046716 26 15 0,000 0,02267252 0,03828077 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02267252 0,03825392 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02267252 0,03822711 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02267252 0,03820035 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02267252 0,03817361 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02267252 0,03814692 ! cell killing GO:0001906 29 15 0,000 0,02267252 0,03812026 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02267252 0,03809364 ! detection of bacterium GO:0016045 18 15 0,000 0,02267252 0,03806706 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02267252 0,03804051 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02267252 0,038014 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02267252 0,03798753 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02267252 0,03796109 ! peptide hormone processing GO:0016486 23 15 0,000 0,02267252 0,0379347 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,02416601 0,04040544 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02416601 0,04037738 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,02416601 0,04034936 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,02416601 0,04032138 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,02416601 0,04029344 ! bone remodeling GO:0046849 27 16 0,000 0,02416601 0,04026553 ! filopodium assembly GO:0046847 32 16 0,000 0,02416601 0,04023767 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,02416601 0,04020984 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,02416601 0,04018205 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,02416601 0,0401543 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,02416601 0,04012659 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,02416601 0,04009892 ! startle response GO:0001964 28 16 0,000 0,02416601 0,04007128 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,02416601 0,04004369 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,02416601 0,04001613 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,02416601 0,03998861 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,02416601 0,03996112 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,02416601 0,03993368 ! protein polyubiquitination GO:0000209 34 16 0,000 0,02416601 0,03990627 ! glutamate metabolic process GO:0006536 22 16 0,000 0,02416601 0,0398789 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,02416601 0,03985156 ! response to osmotic stress GO:0006970 25 16 0,000 0,02416601 0,03982427 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,02416601 0,03979701 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,02416601 0,03976979 ! fructose metabolic process GO:0006000 25 16 0,000 0,02416601 0,03974261 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02416601 0,03971546 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02416601 0,03968835 ! intermediate filament-based process GO:0045103 32 16 0,000 0,02416601 0,03966128 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,02416601 0,03963424 ! negative regulation of immune response GO:0050777 35 16 0,000 0,02416601 0,03960724 ! axon cargo transport GO:0008088 43 16 0,000 0,02416601 0,03958028 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,02416601 0,03955335 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,02416601 0,03952647 ! DNA replication initiation GO:0006270 27 16 0,000 0,02416601 0,03949961 ! neuron recognition GO:0008038 35 16 0,000 0,02416601 0,0394728 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,02416601 0,03944602 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,02416601 0,03941928 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,02416601 0,03939257 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,02416601 0,0393659 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,02416601 0,03933926 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,02416601 0,03931267 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,02416601 0,0392861 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,02416601 0,03925958 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02416601 0,03923308 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,02416601 0,03920663 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,02416601 0,03918021 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,02416601 0,03915383 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02416601 0,03912748 ! defense response to virus GO:0051607 37 16 0,000 0,02416601 0,03910116 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,02565727 0,04148616 ! metencephalon development GO:0022037 30 17 0,000 0,02565727 0,04145829 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,02565727 0,04143047 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,02565727 0,04140268 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,02565727 0,04137493 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,02565727 0,04134722 ! signal complex assembly GO:0007172 41 17 0,000 0,02565727 0,04131954 ! endothelial cell migration GO:0043542 28 17 0,000 0,02565727 0,04129191 ! inositol metabolic process GO:0006020 28 17 0,000 0,02565727 0,0412643 ! gene silencing by RNA GO:0031047 36 17 0,000 0,02565727 0,04123674 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,02565727 0,04120921 ! glial cell development GO:0021782 27 17 0,000 0,02565727 0,04118172 ! limbic system development GO:0021761 36 17 0,000 0,02565727 0,04115427 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,02565727 0,04112685 ! adult walking behavior GO:0007628 33 17 0,000 0,02565727 0,04109947 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,02565727 0,04107212 ! heart looping GO:0001947 30 17 0,000 0,02565727 0,04104481 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,02565727 0,04101754 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,02565727 0,0409903 ! myoblast differentiation GO:0045445 45 17 0,000 0,02565727 0,0409631 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,02565727 0,04093594 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,02565727 0,04090881 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,02565727 0,04088172 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,02565727 0,04085467 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,02565727 0,04082764 ! glycine metabolic process GO:0006544 28 17 0,000 0,02565727 0,04080066 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,02565727 0,04077371 ! NAD metabolic process GO:0019674 29 17 0,000 0,02565727 0,0407468 ! membrane budding GO:0006900 37 17 0,000 0,02565727 0,04071992 ! DNA integration GO:0015074 29 17 0,000 0,02565727 0,04069308 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,02565727 0,04066627 ! regulation of protein binding GO:0043393 33 17 0,000 0,02565727 0,0406395 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,02565727 0,04061276 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,02565727 0,04058606 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,02565727 0,04055939 ! genitalia development GO:0048806 30 17 0,000 0,02565727 0,04053276 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,02565727 0,04050617 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,02565727 0,04047961 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,02565727 0,04045308 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,02565727 0,04042659 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,02565727 0,04040013 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,02565727 0,04037371 ! steroid catabolic process GO:0006706 31 17 0,000 0,02565727 0,04034732 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,02565727 0,04032097 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,02565727 0,04029465 ! gas transport GO:0015669 25 17 0,000 0,02565727 0,04026836 ! organic cation transport GO:0015695 31 17 0,000 0,02565727 0,04024211 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,02565727 0,0402159 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,02565727 0,04018971 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,02565727 0,04016356 ! microspike assembly GO:0030035 36 17 0,000 0,02565727 0,04013745 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,02565727 0,04011137 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,02565727 0,04008532 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,0271463 0,04238417 ! neuron maturation GO:0042551 42 18 0,000 0,0271463 0,04235668 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,0271463 0,04232923 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,0271463 0,04230181 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,0271463 0,04227444 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,0271463 0,04224709 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,0271463 0,04221978 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,0271463 0,04219251 ! memory GO:0007613 31 18 0,000 0,0271463 0,04216527 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0271463 0,04213807 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,0271463 0,0421109 ! patterning of blood vessels GO:0001569 39 18 0,000 0,0271463 0,04208376 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,0271463 0,04205667 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,0271463 0,0420296 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,0271463 0,04200257 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,0271463 0,04197558 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0271463 0,04194862 ! response to retinoic acid GO:0032526 26 18 0,000 0,0271463 0,0419217 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,0271463 0,04189481 ! response to fungus GO:0009620 21 18 0,000 0,0271463 0,04186795 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,0271463 0,04184113 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,0271463 0,04181434 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,0271463 0,04178759 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,0271463 0,04176087 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,0271463 0,04173419 ! vitamin transport GO:0051180 27 18 0,000 0,0271463 0,04170754 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,0271463 0,04168092 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,0271463 0,04165434 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,0271463 0,04162779 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,0271463 0,04160128 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,0271463 0,04157479 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,0271463 0,04154835 ! nerve development GO:0021675 28 18 0,000 0,0271463 0,04152193 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,0271463 0,04149555 ! protein secretion GO:0009306 39 19 0,000 0,0286331 0,04374048 ! positive regulation of translation GO:0045727 30 19 0,000 0,0286331 0,04371272 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0286331 0,043685 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0286331 0,04365732 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0286331 0,04362967 ! skin development GO:0043588 36 19 0,000 0,0286331 0,04360206 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0286331 0,04357448 ! lipid phosphorylation GO:0046834 35 19 0,000 0,0286331 0,04354693 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0286331 0,04351942 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0286331 0,04349195 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0286331 0,04346451 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0286331 0,04343711 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0286331 0,04340973 ! cerebral cortex development GO:0021987 36 19 0,000 0,0286331 0,0433824 ! pigmentation during development GO:0048066 41 19 0,000 0,0286331 0,0433551 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0286331 0,04332783 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,0286331 0,0433006 ! heme metabolic process GO:0042168 36 19 0,000 0,0286331 0,0432734 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0286331 0,04324623 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0286331 0,0432191 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0286331 0,04319201 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0286331 0,04316494 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0286331 0,04313791 ! peptide cross-linking GO:0018149 37 19 0,000 0,0286331 0,04311092 ! protein export from nucleus GO:0006611 36 19 0,000 0,0286331 0,04308396 ! heart process GO:0003015 30 19 0,000 0,0286331 0,04305703 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0286331 0,04303014 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,0286331 0,04300328 ! visual learning GO:0008542 36 19 0,000 0,0286331 0,04297645 ! cellular pigmentation GO:0033059 36 19 0,000 0,0286331 0,04294966 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0286331 0,0429229 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0286331 0,04289617 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0286331 0,04286948 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0286331 0,04284282 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0286331 0,04281619 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0286331 0,0427896 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0286331 0,04276303 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0286331 0,04273651 ! cilium assembly GO:0042384 37 19 0,000 0,0286331 0,04271001 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0286331 0,04268355 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03011768 0,04486882 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03011768 0,04484106 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03011768 0,04481333 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03011768 0,04478563 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03011768 0,04475797 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03011768 0,04473034 ! response to vitamin GO:0033273 31 20 0,000 0,03011768 0,04470274 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03011768 0,04467518 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03011768 0,04464766 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03011768 0,04462016 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03011768 0,04459271 ! response to alkaloid GO:0043279 38 20 0,000 0,03011768 0,04456528 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03011768 0,04453789 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03011768 0,04451053 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03011768 0,04448321 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03011768 0,04445592 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03011768 0,04442866 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03011768 0,04440144 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03011768 0,04437425 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,03011768 0,04434709 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03011768 0,04431997 ! body fluid secretion GO:0007589 31 20 0,000 0,03011768 0,04429288 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03011768 0,04426582 ! peptide secretion GO:0002790 35 20 0,000 0,03011768 0,0442388 ! stem cell differentiation GO:0048863 53 20 0,000 0,03011768 0,0442118 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03011768 0,04418485 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03011768 0,04415792 ! sensory perception of pain GO:0019233 30 20 0,000 0,03011768 0,04413103 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03011768 0,04410417 ! diencephalon development GO:0021536 34 20 0,000 0,03011768 0,04407734 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03011768 0,04405055 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03011768 0,04402378 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03011768 0,04399705 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03011768 0,04397036 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03011768 0,04394369 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03011768 0,04391706 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03011768 0,04389046 ! regulation of glucose import GO:0046324 29 20 0,000 0,03011768 0,04386389 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03011768 0,04383735 ! actin filament-based movement GO:0030048 43 20 0,000 0,03011768 0,04381085 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03011768 0,04378438 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03011768 0,04375794 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03011768 0,04373153 ! negative regulation of translation GO:0017148 29 20 0,000 0,03011768 0,04370516 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03011768 0,04367881 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03011768 0,0436525 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,03160004 0,04577345 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,03160004 0,04574591 ! hormone secretion GO:0046879 38 21 0,000 0,03160004 0,0457184 ! glycerol metabolic process GO:0006071 34 21 0,000 0,03160004 0,04569093 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,03160004 0,04566349 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,03160004 0,04563608 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,03160004 0,0456087 ! axis specification GO:0009798 38 21 0,000 0,03160004 0,04558136 ! ovarian follicle development GO:0001541 35 21 0,000 0,03160004 0,04555405 ! smooth muscle contraction GO:0006939 46 21 0,000 0,03160004 0,04552677 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,03160004 0,04549952 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,03160004 0,04547231 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,03160004 0,04544513 ! cell aging GO:0007569 44 21 0,000 0,03160004 0,04541798 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,03160004 0,04539087 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,03160004 0,04536379 ! cytolysis GO:0019835 24 21 0,000 0,03160004 0,04533674 ! vasodilation GO:0042311 39 21 0,000 0,03160004 0,04530972 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,03160004 0,04528273 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,03160004 0,04525578 ! DNA modification GO:0006304 34 21 0,000 0,03160004 0,04522886 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,03160004 0,04520197 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,03160004 0,04517511 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,03160004 0,04514828 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,03160004 0,04512149 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,03160004 0,04509472 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,03160004 0,04506799 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,03160004 0,04504129 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,03160004 0,04501463 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,03160004 0,04498799 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,03160004 0,04496139 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,03160004 0,04493481 ! collagen catabolic process GO:0030574 28 21 0,000 0,03160004 0,04490827 ! sperm-egg recognition GO:0035036 21 21 0,000 0,03160004 0,04488176 ! gut development GO:0048565 39 21 0,000 0,03160004 0,04485528 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,03308019 0,04692861 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,03308019 0,04690096 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,03308019 0,04687334 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,03308019 0,04684575 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,03308019 0,04681819 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,03308019 0,04679067 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,03308019 0,04676318 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,03308019 0,04673572 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,03308019 0,04670829 ! regeneration GO:0031099 41 22 0,000 0,03308019 0,0466809 ! keratinization GO:0031424 28 22 0,000 0,03308019 0,04665354 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,03308019 0,0466262 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,03308019 0,04659891 ! sensory perception of taste GO:0050909 28 22 0,000 0,03308019 0,04657164 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,03308019 0,0465444 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,03308019 0,0465172 ! vacuolar transport GO:0007034 36 22 0,000 0,03308019 0,04649003 ! lysosome organization GO:0007040 41 22 0,000 0,03308019 0,04646289 ! central nervous system neuron development GO:0021954 46 22 0,000 0,03308019 0,04643578 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,03308019 0,04640871 ! fucose metabolic process GO:0006004 39 22 0,000 0,03308019 0,04638166 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,03308019 0,04635465 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,03308019 0,04632767 ! ureteric bud development GO:0001657 43 22 0,000 0,03308019 0,04630072 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,03308019 0,0462738 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,03308019 0,04624691 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,03308019 0,04622005 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,03308019 0,04619323 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,03308019 0,04616643 ! sarcomere organization GO:0045214 30 22 0,000 0,03308019 0,04613967 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,03308019 0,04611294 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,03308019 0,04608624 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,03308019 0,04605957 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,03308019 0,04603293 ! protein stabilization GO:0050821 39 22 0,000 0,03308019 0,04600632 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,03455812 0,04803399 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,03455812 0,04800625 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,03455812 0,04797855 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,03455812 0,04795088 ! gluconeogenesis GO:0006094 33 23 0,000 0,03455812 0,04792325 ! viral genome replication GO:0019079 41 23 0,000 0,03455812 0,04789564 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,03455812 0,04786807 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,03455812 0,04784052 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,03455812 0,04781301 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,03455812 0,04778554 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,03455812 0,04775809 ! visual behavior GO:0007632 42 23 0,000 0,03455812 0,04773067 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,03455812 0,04770329 ! response to ethanol GO:0045471 46 23 0,000 0,03455812 0,04767594 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,03455812 0,04764861 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,03455812 0,04762132 ! peroxisome organization GO:0007031 37 23 0,000 0,03455812 0,04759406 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,03455812 0,04756684 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,03455812 0,04753964 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,03455812 0,04751247 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,03455812 0,04748534 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,03455812 0,04745824 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,03455812 0,04743116 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,03455812 0,04740412 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,03455812 0,04737711 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,03455812 0,04735013 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,03455812 0,04732318 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,03455812 0,04729626 ! fatty acid transport GO:0015908 44 23 0,000 0,03455812 0,04726938 ! platelet activation GO:0030168 37 23 0,000 0,03455812 0,04724252 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,03455812 0,04721569 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,03455812 0,04718889 ! hormone transport GO:0009914 40 23 0,000 0,03455812 0,04716213 ! cell-cell recognition GO:0009988 25 23 0,000 0,03455812 0,04713539 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,03455812 0,04710869 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,03455812 0,04708201 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,03455812 0,04705537 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,03455812 0,04702875 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,03455812 0,04700217 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,03603384 0,04898159 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,03603384 0,04895393 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,03603384 0,04892631 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,03603384 0,04889871 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,03603384 0,04887115 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,03603384 0,04884361 ! spinal cord development GO:0021510 47 24 0,000 0,03603384 0,04881611 ! vacuole organization GO:0007033 43 24 0,000 0,03603384 0,04878864 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,03603384 0,0487612 ! digestive system process GO:0022600 39 24 0,000 0,03603384 0,04873379 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,03603384 0,04870641 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,03603384 0,04867906 ! regulation of behavior GO:0050795 43 24 0,000 0,03603384 0,04865175 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,03603384 0,04862446 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,03603384 0,04859721 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,03603384 0,04856998 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,03603384 0,04854279 ! pallium development GO:0021543 49 24 0,000 0,03603384 0,04851562 ! pentose metabolic process GO:0019321 35 24 0,000 0,03603384 0,04848849 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,03603384 0,04846138 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,03603384 0,04843431 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,03603384 0,04840727 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,03603384 0,04838025 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,03603384 0,04835327 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,03603384 0,04832632 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,03603384 0,0482994 ! regulation of amine transport GO:0051952 40 24 0,000 0,03603384 0,0482725 ! protein tetramerization GO:0051262 52 24 0,000 0,03603384 0,04824564 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,03750735 0,05019059 ! myelination GO:0042552 45 25 0,000 0,03750735 0,05016269 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,03750735 0,05013483 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,03750735 0,05010699 ! phototransduction GO:0007602 33 25 0,000 0,03750735 0,05007918 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,03750735 0,05005141 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,03750735 0,05002366 ! sperm motility GO:0030317 31 25 0,000 0,03750735 0,04999595 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,03750735 0,04996827 ! receptor metabolic process GO:0043112 46 25 0,000 0,03750735 0,04994061 ! chromosome condensation GO:0030261 45 25 0,000 0,03750735 0,04991299 ! response to starvation GO:0042594 42 25 0,000 0,03750735 0,0498854 ! osteoblast differentiation GO:0001649 60 25 0,000 0,03750735 0,04985784 ! neural crest cell development GO:0014032 54 25 0,000 0,03750735 0,04983031 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,03750735 0,04980281 ! negative regulation of cell development GO:0010721 73 25 0,000 0,03750735 0,04977534 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,03750735 0,0497479 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,03750735 0,04972049 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,03750735 0,04969311 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,03750735 0,04966576 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,03750735 0,04963844 ! immunoglobulin production GO:0002377 55 25 0,000 0,03750735 0,04961115 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,03750735 0,04958389 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,03750735 0,04955667 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,03750735 0,04952947 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,03750735 0,0495023 ! telomere organization GO:0032200 43 25 0,000 0,03750735 0,04947516 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,03750735 0,04944805 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,03750735 0,04942097 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,03897866 0,05133151 ! embryonic pattern specification GO:0009880 44 26 0,000 0,03897866 0,05130342 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,03897866 0,05127537 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,03897866 0,05124736 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,03897866 0,05121937 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,03897866 0,05119141 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,03897866 0,05116348 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,03897866 0,05113558 ! molting cycle process GO:0022404 50 26 0,000 0,03897866 0,05110772 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,03897866 0,05107988 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,03897866 0,05105207 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,03897866 0,0510243 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,03897866 0,05099655 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,03897866 0,05096884 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,03897866 0,05094115 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,03897866 0,0509135 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,03897866 0,05088587 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,03897866 0,05085828 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,03897866 0,05083071 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,03897866 0,05080317 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,03897866 0,05077567 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,03897866 0,05074819 ! blastocyst development GO:0001824 49 26 0,000 0,03897866 0,05072075 ! leukocyte proliferation GO:0070661 52 26 0,000 0,03897866 0,05069333 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,03897866 0,05066594 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,03897866 0,05063859 ! neuron fate commitment GO:0048663 48 27 0,000 0,04044777 0,0525188 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,04044777 0,05249047 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,04044777 0,05246218 ! iron ion transport GO:0006826 59 27 0,000 0,04044777 0,05243391 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,04044777 0,05240567 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,04044777 0,05237747 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,04044777 0,05234929 ! fat cell differentiation GO:0045444 50 27 0,000 0,04044777 0,05232115 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,04044777 0,05229303 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,04044777 0,05226495 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,04044777 0,0522369 ! autophagy GO:0006914 41 27 0,000 0,04044777 0,05220887 ! male gonad development GO:0008584 44 27 0,000 0,04044777 0,05218088 ! response to toxin GO:0009636 47 27 0,000 0,04044777 0,05215291 ! primary neural tube formation GO:0014020 51 27 0,000 0,04044777 0,05212498 ! base-excision repair GO:0006284 41 27 0,000 0,04044777 0,05209708 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,04044777 0,0520692 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,04044777 0,05204136 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,04044777 0,05201354 ! glutathione metabolic process GO:0006749 39 27 0,000 0,04044777 0,05198576 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,04044777 0,051958 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,04044777 0,05193028 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,04044777 0,05190258 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,04044777 0,05187491 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,04191468 0,05372761 ! circadian rhythm GO:0007623 50 28 0,000 0,04191468 0,053699 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,04191468 0,05367043 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,04191468 0,05364188 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,04191468 0,05361336 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,04191468 0,05358487 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,04191468 0,05355642 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,04191468 0,05352799 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,04191468 0,05349959 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,04191468 0,05347122 ! synaptogenesis GO:0007416 42 28 0,000 0,04191468 0,05344289 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,04191468 0,05341458 ! lipid oxidation GO:0034440 43 28 0,000 0,04191468 0,0533863 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,04191468 0,05335806 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,04191468 0,05332984 ! translational initiation GO:0006413 65 29 0,000 0,0433794 0,05516429 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0433794 0,05513515 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0433794 0,05510604 ! regulation of pH GO:0006885 43 29 0,000 0,0433794 0,05507696 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0433794 0,05504791 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0433794 0,05501889 ! catechol metabolic process GO:0009712 54 29 0,000 0,0433794 0,05498991 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0433794 0,05496095 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0433794 0,05493202 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0433794 0,05490313 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0433794 0,05487426 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0433794 0,05484542 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0433794 0,05481662 ! cell fate determination GO:0001709 60 29 0,000 0,0433794 0,05478784 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0433794 0,0547591 ! detection of light stimulus GO:0009583 38 29 0,000 0,0433794 0,05473038 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,0433794 0,0547017 ! tissue homeostasis GO:0001894 48 29 0,000 0,0433794 0,05467305 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,04484193 0,05648675 ! zinc ion transport GO:0006829 45 30 0,000 0,04484193 0,05645719 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,04484193 0,05642766 ! cell junction assembly GO:0034329 78 30 0,000 0,04484193 0,05639816 ! regulation of innate immune response GO:0045088 51 30 0,000 0,04484193 0,0563687 ! acute-phase response GO:0006953 49 30 0,000 0,04484193 0,05633926 ! myofibril assembly GO:0030239 47 30 0,000 0,04484193 0,05630986 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,04484193 0,05628048 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,04484193 0,05625114 ! phospholipid transport GO:0015914 51 30 0,000 0,04484193 0,05622183 ! ensheathment of neurons GO:0007272 57 30 0,000 0,04484193 0,05619254 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,04484193 0,05616329 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,04484193 0,05613407 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,04484193 0,05610488 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,04484193 0,05607572 ! eye morphogenesis GO:0048592 60 30 0,000 0,04484193 0,05604659 ! response to heat GO:0009408 50 30 0,000 0,04484193 0,05601749 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,04630227 0,05781176 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,04630227 0,05778178 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,04630227 0,05775182 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,04630227 0,0577219 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,04630227 0,05769201 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,04630227 0,05766215 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,04630227 0,05763232 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,04630227 0,05760252 ! ovulation cycle process GO:0022602 49 31 0,000 0,04630227 0,05757275 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,04630227 0,05754301 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,04630227 0,0575133 ! peptide transport GO:0015833 55 31 0,000 0,04630227 0,05748363 ! iron ion homeostasis GO:0055072 54 31 0,000 0,04630227 0,05745398 ! mesoderm formation GO:0001707 69 31 0,000 0,04630227 0,05742436 ! natural killer cell activation GO:0030101 45 31 0,000 0,04630227 0,05739478 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,04630227 0,05736522 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,04630227 0,0573357 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,04630227 0,05730621 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,04630227 0,05727674 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,04630227 0,05724731 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,04776043 0,05901982 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,04776043 0,05898952 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,04776043 0,05895926 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,04776043 0,05892902 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,04776043 0,05889882 ! spliceosome assembly GO:0000245 67 32 0,000 0,04776043 0,05886864 ! spindle organization GO:0007051 46 32 0,000 0,04776043 0,0588385 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,04776043 0,05880839 ! metanephros development GO:0001656 74 32 0,000 0,04776043 0,05877831 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,04776043 0,05874826 ! response to ionizing radiation GO:0010212 65 32 0,000 0,04776043 0,05871824 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,04776043 0,05868825 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,04776043 0,05865829 ! muscle cell development GO:0055001 49 32 0,000 0,04776043 0,05862836 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,04776043 0,05859847 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,04776043 0,0585686 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,04776043 0,05853876 ! ovulation cycle GO:0042698 51 32 0,000 0,04776043 0,05850896 ! peripheral nervous system development GO:0007422 64 32 0,000 0,04776043 0,05847918 ! BMP signaling pathway GO:0030509 64 32 0,000 0,04776043 0,05844944 ! hindbrain development GO:0030902 61 32 0,000 0,04776043 0,05841972 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,04776043 0,05839004 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,04776043 0,05836038 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,04776043 0,05833076 ! gene silencing GO:0016458 65 32 0,000 0,04776043 0,05830116 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0492164 0,06004801 ! post-embryonic development GO:0009791 69 33 0,000 0,0492164 0,06001757 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0492164 0,05998717 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0492164 0,05995679 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0492164 0,05992645 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0492164 0,05989614 ! formation of primary germ layer GO:0001704 72 33 0,000 0,0492164 0,05986586 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0492164 0,05983561 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0492164 0,05980539 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0492164 0,0597752 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0492164 0,05974504 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,0506702 0,06147882 ! glial cell differentiation GO:0010001 63 34 0,000 0,0506702 0,06144783 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,0506702 0,06141688 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,0506702 0,06138595 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,0506702 0,06135506 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,0506702 0,0613242 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,0506702 0,06129337 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,0506702 0,06126256 ! mismatch repair GO:0006298 46 34 0,000 0,0506702 0,0612318 ! spermatid development GO:0007286 63 34 0,000 0,0506702 0,06120106 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,0506702 0,06117035 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,0506702 0,06113967 ! placenta development GO:0001890 53 34 0,000 0,0506702 0,06110902 ! regulation of muscle development GO:0048634 70 35 0,000 0,05212182 0,06282821 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,05212182 0,06279675 ! negative regulation of secretion GO:0051048 63 35 0,000 0,05212182 0,06276532 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,05212182 0,06273392 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,05212182 0,06270255 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,05212182 0,06267122 ! odontogenesis GO:0042476 66 35 0,000 0,05212182 0,06263991 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,05212182 0,06260864 ! female gonad development GO:0008585 58 35 0,000 0,05212182 0,0625774 ! telencephalon development GO:0021537 68 35 0,000 0,05212182 0,06254619 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,05212182 0,06251501 ! cytokine production GO:0001816 59 35 0,000 0,05212182 0,06248386 ! neural tube formation GO:0001841 67 35 0,000 0,05212182 0,06245274 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,05357128 0,06415754 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,05357128 0,06412562 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,05357128 0,06409373 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,05357128 0,06406187 ! cell junction organization GO:0034330 86 36 0,000 0,05357128 0,06403005 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,05357128 0,06399826 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,05357128 0,0639665 ! positive regulation of cell development GO:0010720 80 36 0,000 0,05357128 0,06393477 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,05357128 0,06390307 ! regulation of proteolysis GO:0030162 72 36 0,000 0,05357128 0,0638714 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,05357128 0,06383977 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,05357128 0,06380816 ! aerobic respiration GO:0009060 55 36 0,000 0,05357128 0,06377659 ! embryonic organ development GO:0048568 57 36 0,000 0,05357128 0,06374505 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,05357128 0,06371354 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,05357128 0,06368206 ! RNA export from nucleus GO:0006405 56 37 0,000 0,05501856 0,0653702 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,05501856 0,06533793 ! meiosis I GO:0007127 65 37 0,000 0,05501856 0,0653057 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,05501856 0,0652735 ! sister chromatid segregation GO:0000819 58 37 0,000 0,05501856 0,06524133 ! actomyosin structure organization GO:0031032 62 37 0,000 0,05501856 0,06520919 ! organic anion transport GO:0015711 68 37 0,000 0,05501856 0,06517708 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,05501856 0,06514501 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,05501856 0,06511296 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,05501856 0,06508095 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,05501856 0,06504897 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,05501856 0,06501702 ! pigment metabolic process GO:0042440 80 37 0,000 0,05501856 0,0649851 ! spermatid differentiation GO:0048515 66 37 0,000 0,05501856 0,06495321 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,05501856 0,06492136 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,05646368 0,06659392 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,05646368 0,0665613 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,05646368 0,0665287 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,05646368 0,06649614 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,05646368 0,0664636 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,05646368 0,0664311 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,05646368 0,06639863 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,05646368 0,0663662 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,05646368 0,06633379 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,05646368 0,06630142 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,05646368 0,06626908 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,05646368 0,06623677 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,05646368 0,06620449 ! mRNA catabolic process GO:0006402 71 39 0,000 0,05790663 0,0678633 ! learning GO:0007612 77 39 0,000 0,05790663 0,06783026 ! ear morphogenesis GO:0042471 60 39 0,000 0,05790663 0,06779725 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,05790663 0,06776428 ! segmentation GO:0035282 67 39 0,000 0,05790663 0,06773134 ! ion transmembrane transport GO:0034220 66 39 0,000 0,05790663 0,06769842 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,05790663 0,06766555 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,05790663 0,0676327 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,05790663 0,06759988 ! RNA modification GO:0009451 57 39 0,000 0,05790663 0,0675671 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,05790663 0,06753435 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,05934743 0,06918116 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,05934743 0,06914766 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,05934743 0,06911419 ! feeding behavior GO:0007631 59 40 0,000 0,05934743 0,06908075 ! negative regulation of binding GO:0051100 72 40 0,000 0,05934743 0,06904735 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,05934743 0,06901398 ! mesenchymal cell development GO:0014031 87 40 0,000 0,05934743 0,06898064 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,05934743 0,06894733 ! maintenance of protein location GO:0045185 91 40 0,000 0,05934743 0,06891405 ! cytokinesis GO:0000910 72 40 0,000 0,05934743 0,06888081 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,06078607 0,07051653 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,06078607 0,07048255 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,06078607 0,0704486 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,06078607 0,07041468 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,06078607 0,07038079 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,06078607 0,07034694 ! T cell differentiation GO:0030217 81 41 0,000 0,06078607 0,07031312 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,06078607 0,07027933 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,06078607 0,07024557 ! polyol metabolic process GO:0019751 66 41 0,000 0,06078607 0,07021185 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,06078607 0,07017816 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,06222256 0,07180215 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,06222256 0,07176773 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,06222256 0,07173334 ! regulation of tube size GO:0035150 71 42 0,000 0,06222256 0,07169898 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,06222256 0,07166466 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,06222256 0,07163037 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,06222256 0,07159612 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,06222256 0,07156189 ! neuron migration GO:0001764 79 42 0,000 0,06222256 0,0715277 ! regulation of protein secretion GO:0050708 71 42 0,000 0,06222256 0,07149354 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,0636569 0,07310668 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0636569 0,0730718 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0636569 0,07303696 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0636569 0,07300214 ! glucose transport GO:0015758 65 43 0,000 0,0636569 0,07296737 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0636569 0,07293262 ! neural tube development GO:0021915 77 43 0,000 0,0636569 0,07289791 ! striated muscle contraction GO:0006941 77 43 0,000 0,0636569 0,07286323 ! phagocytosis GO:0006909 90 43 0,000 0,0636569 0,07282858 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0636569 0,07279396 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,06508909 0,07439637 ! hexose transport GO:0008645 67 44 0,000 0,06508909 0,07436104 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,06508909 0,07432575 ! male sex differentiation GO:0046661 76 44 0,000 0,06508909 0,07429049 ! double-strand break repair GO:0006302 81 44 0,000 0,06508909 0,07425527 ! biopolymer methylation GO:0043414 84 44 0,000 0,06508909 0,07422007 ! B cell differentiation GO:0030183 107 44 0,000 0,06508909 0,07418492 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,06508909 0,07414979 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,06508909 0,0741147 ! developmental growth GO:0048589 82 44 0,000 0,06508909 0,07407964 ! maintenance of location in cell GO:0051651 97 44 0,000 0,06508909 0,07404461 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,06651914 0,07563566 ! glycolysis GO:0006096 65 45 0,000 0,06651914 0,07559993 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,06651914 0,07556424 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,06651914 0,07552858 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,06651914 0,07549295 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,06651914 0,07545736 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,06651914 0,0754218 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,06651914 0,07538627 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,06651914 0,07535078 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,06794705 0,07693205 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,06794705 0,07689587 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,06794705 0,07685971 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,06794705 0,07682359 ! pigmentation GO:0043473 100 46 0,000 0,06794705 0,07678751 ! response to insulin stimulus GO:0032868 95 46 0,000 0,06794705 0,07675146 ! positive regulation of defense response GO:0031349 76 47 0,000 0,06937283 0,07832521 ! response to calcium ion GO:0051592 81 47 0,000 0,06937283 0,07828847 ! endosome transport GO:0016197 108 47 0,000 0,06937283 0,07825177 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,06937283 0,0782151 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,06937283 0,07817846 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,06937283 0,07814186 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,06937283 0,0781053 ! JNK cascade GO:0007254 91 47 0,000 0,06937283 0,07806877 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,06937283 0,07803227 ! methylation GO:0032259 90 47 0,000 0,06937283 0,0779958 ! mitochondrial transport GO:0006839 82 48 0,000 0,07079647 0,07955922 ! Notch signaling pathway GO:0007219 96 48 0,000 0,07079647 0,07952208 ! cellular component disassembly GO:0022411 86 48 0,000 0,07079647 0,07948497 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,07079647 0,0794479 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,07079647 0,07941086 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,07079647 0,07937386 ! activation of caspase activity GO:0006919 84 48 0,000 0,07079647 0,07933689 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,07079647 0,07929995 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,07079647 0,07926305 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,07079647 0,07922619 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,07221798 0,08077938 ! regulation of action potential GO:0001508 95 49 0,000 0,07221798 0,08074184 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,07221798 0,08070434 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,07221798 0,08066688 ! regulation of ion transport GO:0043269 77 49 0,000 0,07221798 0,08062944 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,07221798 0,08059205 ! peptide metabolic process GO:0006518 76 49 0,000 0,07221798 0,08055468 ! response to temperature stimulus GO:0009266 76 49 0,000 0,07221798 0,08051735 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,07221798 0,08048006 ! endocrine system development GO:0035270 104 49 0,000 0,07221798 0,0804428 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,07221798 0,08040558 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,07221798 0,08036839 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,07221798 0,08033123 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,07221798 0,08029411 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,07363736 0,0818344 ! neuromuscular process GO:0050905 99 50 0,000 0,07363736 0,08179662 ! inner ear development GO:0048839 79 50 0,000 0,07363736 0,08175888 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,07363736 0,08172116 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,07363736 0,08168349 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,07363736 0,08164584 ! positive regulation of binding GO:0051099 78 51 0,000 0,07505462 0,08317891 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,07505462 0,08314061 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,07505462 0,08310235 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,07505462 0,08306412 ! excretion GO:0007588 83 51 0,000 0,07505462 0,08302593 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,07505462 0,08298778 ! chromatin remodeling GO:0006338 109 51 0,000 0,07505462 0,08294966 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,07505462 0,08291157 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,07505462 0,08287352 ! regulation of cell shape GO:0008360 125 51 0,000 0,07505462 0,08283551 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,07505462 0,08279753 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,07646975 0,08431999 ! positive regulation of growth GO:0045927 90 52 0,000 0,07646975 0,08428137 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,07646975 0,08424278 ! amino acid activation GO:0043038 92 52 0,000 0,07646975 0,08420422 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,07646975 0,0841657 ! synapse organization GO:0050808 85 52 0,000 0,07646975 0,08412722 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,07788277 0,08564257 ! RNA catabolic process GO:0006401 93 53 0,000 0,07788277 0,08560345 ! regulation of translational initiation GO:0006446 82 53 0,000 0,07788277 0,08556436 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,07788277 0,08552531 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,07788277 0,08548629 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,07788277 0,08544731 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,07788277 0,08540836 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,07929367 0,08691598 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,07929367 0,0868764 ! cell recognition GO:0008037 85 54 0,000 0,07929367 0,08683686 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,07929367 0,08679735 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,07929367 0,08675788 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,07929367 0,08671844 ! chloride transport GO:0006821 90 55 0,000 0,08070246 0,08821905 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,08070246 0,08817899 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,08070246 0,08813896 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,08070246 0,08809897 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,08070246 0,08805902 ! aging GO:0007568 103 55 0,000 0,08070246 0,0880191 ! gastrulation GO:0007369 112 55 0,000 0,08070246 0,08797922 ! heart morphogenesis GO:0003007 97 55 0,000 0,08070246 0,08793937 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,08070246 0,08789956 ! RNA elongation GO:0006354 79 55 0,000 0,08070246 0,08785979 ! nuclear export GO:0051168 97 55 0,000 0,08070246 0,08782005 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,08070246 0,08778035 ! regulation of actin filament length GO:0030832 105 56 0,000 0,08210915 0,08927004 ! sensory perception of smell GO:0007608 80 56 0,000 0,08210915 0,08922972 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,08210915 0,08918944 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,08210915 0,08914919 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,08210915 0,08910898 ! regulation of DNA replication GO:0006275 101 56 0,000 0,08210915 0,0890688 ! proton transport GO:0015992 94 56 0,000 0,08210915 0,08902866 ! muscle fiber development GO:0048747 112 57 0,000 0,08351372 0,09051082 ! lipid modification GO:0030258 97 57 0,000 0,08351372 0,09047007 ! maintenance of location GO:0051235 118 57 0,000 0,08351372 0,09042935 ! hydrogen transport GO:0006818 97 58 0,000 0,0849162 0,0919066 ! regulation of endocytosis GO:0030100 91 58 0,000 0,0849162 0,09186527 ! adult behavior GO:0030534 99 58 0,000 0,0849162 0,09182399 ! positive regulation of secretion GO:0051047 95 59 0,000 0,08631657 0,09329635 ! regulation of cellular component size GO:0032535 109 59 0,000 0,08631657 0,09325445 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,08631657 0,0932126 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,08631657 0,09317078 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,08631657 0,093129 ! DNA catabolic process GO:0006308 86 59 0,000 0,08631657 0,09308726 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,08631657 0,09304555 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,08771485 0,09451049 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,08771485 0,09446819 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,08771485 0,09442592 ! regulation of heart contraction GO:0008016 110 60 0,000 0,08771485 0,09438369 ! camera-type eye development GO:0043010 116 60 0,000 0,08771485 0,0943415 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,08771485 0,09429934 ! kidney development GO:0001822 122 60 0,000 0,08771485 0,09425723 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,08911103 0,0957148 ! mesoderm development GO:0007498 119 61 0,000 0,08911103 0,09567209 ! tRNA processing GO:0008033 89 61 0,000 0,08911103 0,09562941 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,08911103 0,09558678 ! response to peptide hormone stimulus GO:0043434 122 61 0,000 0,08911103 0,09554418 ! ear development GO:0043583 103 62 0,000 0,09050513 0,0969957 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,09050513 0,09695251 ! gonad development GO:0008406 98 62 0,000 0,09050513 0,09690936 ! regulation of mitosis GO:0007088 105 63 0,000 0,09189713 0,0983561 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,09189713 0,09831236 ! detection of external stimulus GO:0009581 91 63 0,000 0,09189713 0,09826867 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,09189713 0,09822501 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,09328706 0,09966637 ! cell redox homeostasis GO:0045454 102 64 0,000 0,09328706 0,09962213 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,09328706 0,09957793 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,09328706 0,09953377 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,0946749 0,10096977 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,0946749 0,10092504 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,0946749 0,10088034 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,09606066 0,10231162 ! actin filament organization GO:0007015 148 66 0,000 0,09606066 0,10226635 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,09606066 0,10222112 ! extracellular matrix organization GO:0030198 133 66 0,000 0,09606066 0,10217593 ! secondary metabolic process GO:0019748 116 66 0,000 0,09606066 0,10213078 ! cell projection assembly GO:0030031 120 66 0,000 0,09606066 0,10208567 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,09744435 0,10351042 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,09744435 0,10346474 ! activation of MAPK activity GO:0000187 115 67 0,000 0,09744435 0,1034191 ! chromosome segregation GO:0007059 113 67 0,000 0,09744435 0,1033735 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,09744435 0,10332794 ! hexose catabolic process GO:0019320 104 67 0,000 0,09744435 0,10328243 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,09744435 0,10323695 ! activation of immune response GO:0002253 105 67 0,000 0,09744435 0,10319151 ! amino acid transport GO:0006865 125 68 0,000 0,09882597 0,10460857 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,09882597 0,10456257 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,09882597 0,1045166 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,09882597 0,10447068 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,09882597 0,1044248 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,10020551 0,10583602 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,10020551 0,10578958 ! urogenital system development GO:0001655 137 69 0,000 0,10020551 0,10574319 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,10020551 0,10569683 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,10020551 0,10565051 ! appendage morphogenesis GO:0035107 135 70 0,000 0,10158299 0,10705593 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,10295841 0,10845794 ! reproductive structure development GO:0048608 113 71 0,000 0,10295841 0,10841048 ! appendage development GO:0048736 136 71 0,000 0,10295841 0,10836305 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,10295841 0,10831567 ! B cell activation GO:0042113 160 71 0,000 0,10295841 0,10826833 ! acute inflammatory response GO:0002526 113 72 0,000 0,10433177 0,10966459 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,10433177 0,1096167 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,10433177 0,10956885 ! carbohydrate transport GO:0008643 110 72 0,000 0,10433177 0,10952105 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,10433177 0,10947328 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,10433177 0,10942556 ! learning or memory GO:0007611 147 73 0,000 0,10570307 0,11081551 ! regulation of blood pressure GO:0008217 125 73 0,000 0,10570307 0,11076724 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,10570307 0,11071902 ! axon guidance GO:0007411 139 73 0,000 0,10570307 0,11067084 ! fertilization GO:0009566 90 73 0,000 0,10570307 0,1106227 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,10707232 0,11200695 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,10707232 0,11195828 ! neurotransmitter transport GO:0006836 123 74 0,000 0,10707232 0,11190964 ! exocytosis GO:0006887 133 74 0,000 0,10707232 0,11186105 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,10707232 0,1118125 ! eye development GO:0001654 143 74 0,000 0,10707232 0,11176399 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,10843951 0,11314201 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,10843951 0,11309296 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,10843951 0,11304396 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,10843951 0,11299501 ! rhythmic process GO:0048511 128 75 0,000 0,10843951 0,11294609 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,10843951 0,11289722 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,10980466 0,11426904 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,10980466 0,11421964 ! defense response to bacterium GO:0042742 89 76 0,000 0,10980466 0,11417028 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,10980466 0,11412096 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,10980466 0,11407168 ! regulation of catabolic process GO:0009894 161 76 0,000 0,10980466 0,11402245 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,11116777 0,11538811 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,11116777 0,11533835 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,11116777 0,11528864 ! blood coagulation GO:0007596 146 78 0,000 0,11252883 0,11664987 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,11252883 0,11659964 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,11252883 0,11654944 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,11252883 0,11649929 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,11388785 0,11785555 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,11388785 0,11780489 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,11388785 0,11775426 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,11388785 0,11770368 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,11388785 0,11765314 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,11524484 0,11900389 ! response to metal ion GO:0010038 140 80 0,000 0,11524484 0,11895284 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,11524484 0,11890183 ! protein import into nucleus GO:0006606 158 80 0,000 0,11524484 0,11885087 ! inorganic anion transport GO:0015698 138 80 0,000 0,11524484 0,11879995 ! digestion GO:0007586 112 81 0,000 0,11659979 0,12014522 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,11659979 0,12009379 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,11659979 0,1200424 ! nuclear import GO:0051170 161 81 0,000 0,11659979 0,11999106 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,11659979 0,11993976 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,11795271 0,12127958 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,11795271 0,12122778 ! response to drug GO:0042493 143 82 0,000 0,11795271 0,12117601 ! response to nutrient GO:0007584 125 82 0,000 0,11795271 0,1211243 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,11795271 0,12107262 ! cellular response to hormone stimulus GO:0032870 167 82 0,000 0,11795271 0,12102099 ! regulation of lyase activity GO:0051339 160 83 0,000 0,11930361 0,12235485 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,12065248 0,1236855 ! hemostasis GO:0007599 158 84 0,000 0,12065248 0,12363282 ! negative regulation of transport GO:0051051 153 84 0,000 0,12065248 0,12358019 ! regulation of ligase activity GO:0051340 142 84 0,000 0,12065248 0,1235276 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,12065248 0,12347506 ! response to unfolded protein GO:0006986 131 85 0,000 0,12199933 0,12480034 ! nucleosome assembly GO:0006334 122 85 0,000 0,12199933 0,1247473 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,12199933 0,12469431 ! amine biosynthetic process GO:0009309 138 86 0,000 0,12334417 0,12601531 ! response to inorganic substance GO:0010035 153 86 0,000 0,12334417 0,12596183 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,12334417 0,12590838 ! chromatin assembly GO:0031497 124 86 0,000 0,12334417 0,12585499 ! tube morphogenesis GO:0035239 176 86 0,000 0,12334417 0,12580164 ! mitochondrion organization GO:0007005 148 86 0,000 0,12334417 0,12574833 ! alcohol catabolic process GO:0046164 130 86 0,000 0,12334417 0,12569507 ! amine transport GO:0015837 155 86 0,000 0,12334417 0,12564186 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,12468698 0,12695594 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,12468698 0,12690223 ! protein localization in nucleus GO:0034504 176 87 0,000 0,12468698 0,12684858 ! cellular respiration GO:0045333 135 88 0,000 0,12602779 0,12815844 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,12602779 0,12810429 ! regulation of DNA binding GO:0051101 155 88 0,000 0,12602779 0,1280502 ! regulation of neurological system process GO:0031644 148 88 0,000 0,12602779 0,12799614 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,12602779 0,12794214 ! cellular defense response GO:0006968 114 89 0,000 0,12736659 0,12924673 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,12736659 0,12919225 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,12870338 0,13049318 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,12870338 0,13043822 ! sex differentiation GO:0007548 145 90 0,000 0,12870338 0,13038329 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,12870338 0,13032842 ! sterol metabolic process GO:0016125 152 91 0,000 0,13003816 0,13162466 ! response to protein stimulus GO:0051789 149 91 0,000 0,13003816 0,13156931 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,13003816 0,13151401 ! regulation of defense response GO:0031347 149 92 0,000 0,13137095 0,13280609 ! nucleosome organization GO:0034728 138 92 0,000 0,13137095 0,13275032 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,13137095 0,13269459 ! vitamin metabolic process GO:0006766 139 92 0,000 0,13137095 0,1326389 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,13270174 0,13392634 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,13270174 0,13387018 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,13270174 0,13381408 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,13403053 0,13509739 ! female pregnancy GO:0007565 164 94 0,000 0,13403053 0,13504081 ! transcription initiation GO:0006352 153 94 0,000 0,13403053 0,13498429 ! regulation of T cell activation GO:0050863 158 94 0,000 0,13403053 0,13492781 ! forebrain development GO:0030900 188 95 0,000 0,13535734 0,1362065 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,13535734 0,13614956 ! leukocyte differentiation GO:0002521 202 96 0,000 0,13668215 0,13742468 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,13668215 0,13736727 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,13668215 0,13730992 ! positive regulation of immune response GO:0050778 156 96 0,000 0,13668215 0,13725261 ! detection of stimulus GO:0051606 151 96 0,000 0,13668215 0,13719535 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,13800498 0,13846538 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,13800498 0,13840766 ! protein ubiquitination GO:0016567 217 97 0,000 0,13800498 0,13834999 ! hormone metabolic process GO:0042445 157 97 0,000 0,13800498 0,13829237 ! response to virus GO:0009615 160 98 0,000 0,13932582 0,13955784 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,13932582 0,13949976 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,13932582 0,13944173 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,14064469 0,14070317 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,14064469 0,14064469