pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/639-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 2,76E-07 6,742E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 5,411E-07 6,61E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,295E-06 1,055E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 2,799E-06 1,71E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,936E-06 1,434E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 2,966E-06 1,208E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 3,422E-06 1,194E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 3,707E-06 1,132E-03 ! G1 phase GO:0051318 44 22 2,000 3,958E-06 1,074E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 3,958E-06 9,67E-04 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 5,894E-06 1,309E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 8,37E-06 1,704E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 2,000 9,326E-06 1,753E-03 ! membrane docking GO:0022406 69 35 2,000 1,661E-05 2,898E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 1,934E-05 3,15E-03 ! T cell activation during immune response GO:0002286 9 5 1,000 1,934E-05 2,953E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,934E-05 2,779E-03 ! female meiosis GO:0007143 10 5 1,000 1,934E-05 2,625E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,934E-05 2,487E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 1,934E-05 2,362E-03 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 2,893E-05 3,365E-03 ! virion attachment to host cell surface receptor GO:0019062 16 6 1,000 2,898E-05 3,219E-03 ! T cell mediated immunity GO:0002456 17 6 1,000 2,898E-05 3,079E-03 ! interaction with symbiont GO:0051702 14 6 1,000 2,898E-05 2,95E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 2,898E-05 2,832E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 2,898E-05 2,723E-03 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 3,107E-05 2,811E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 3,565E-05 3,11E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 3,81E-05 3,209E-03 ! positive regulation of protein transport GO:0051222 80 46 2,000 3,81E-05 3,102E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,054E-05 3,195E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 4,054E-05 3,095E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 4,054E-05 3,001E-03 ! vesicle fusion GO:0006906 20 7 1,000 4,054E-05 2,913E-03 ! membrane to membrane docking GO:0022614 14 7 1,000 4,054E-05 2,83E-03 ! lymphocyte activation during immune response GO:0002285 11 7 1,000 4,054E-05 2,751E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 4,054E-05 2,677E-03 ! protein homooligomerization GO:0051260 84 49 2,000 4,61E-05 2,964E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 5,401E-05 3,383E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 5,401E-05 3,299E-03 ! ER overload response GO:0006983 13 8 1,000 5,401E-05 3,218E-03 ! gas homeostasis GO:0033483 14 8 1,000 5,401E-05 3,141E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 5,401E-05 3,068E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 5,401E-05 2,999E-03 ! response to UV GO:0009411 120 55 2,000 6,526E-05 3,543E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 6,938E-05 3,684E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 6,938E-05 3,606E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 6,938E-05 3,531E-03 ! regulation of intracellular transport GO:0032386 108 57 2,000 7,264E-05 3,622E-03 ! positive regulation of cell migration GO:0030335 137 58 2,000 7,653E-05 3,739E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 8,664E-05 4,15E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 8,664E-05 4,071E-03 ! induction of an organ GO:0001759 17 10 1,000 8,664E-05 3,994E-03 ! leukocyte activation during immune response GO:0002366 15 10 1,000 8,664E-05 3,92E-03 GO:0002263|cell activation during immune response, ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 8,664E-05 3,848E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,058E-04 4,616E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,058E-04 4,535E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,058E-04 4,456E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,058E-04 4,381E-03 ! oocyte development GO:0048599 20 11 1,000 1,058E-04 4,308E-03 ! positive regulation of cell motion GO:0051272 157 65 2,000 1,076E-04 4,309E-03 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 1,126E-04 4,437E-03 ! negative regulation of cell growth GO:0030308 142 67 2,000 1,178E-04 4,566E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,268E-04 4,842E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,268E-04 4,767E-03 ! entry into host cell GO:0030260 34 12 1,000 1,268E-04 4,695E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 1,268E-04 4,625E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,268E-04 4,557E-03 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,268E-04 4,491E-03 ! oocyte differentiation GO:0009994 21 12 1,000 1,268E-04 4,427E-03 ! developmental induction GO:0031128 22 12 1,000 1,268E-04 4,365E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 1,268E-04 4,304E-03 ! negative regulation of cell size GO:0045792 144 69 2,000 1,285E-04 4,302E-03 ! organelle fusion GO:0048284 36 13 1,000 1,498E-04 4,945E-03 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,498E-04 4,879E-03 ! gland morphogenesis GO:0022612 31 13 1,000 1,498E-04 4,814E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 1,498E-04 4,752E-03 ! lipid localization GO:0010876 32 14 1,000 1,746E-04 5,468E-03 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 1,746E-04 5,399E-03 ! protein oligomerization GO:0051259 149 79 2,000 1,921E-04 5,866E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,013E-04 6,07E-03 ! regulation of vasodilation GO:0042312 27 15 1,000 2,013E-04 5,996E-03 ! response to hypoxia GO:0001666 178 81 2,000 2,068E-04 6,088E-03 ! regulation of peptidase activity GO:0052547 150 82 2,000 2,145E-04 6,238E-03 ! response to oxygen levels GO:0070482 183 83 2,000 2,223E-04 6,389E-03 ! heterophilic cell adhesion GO:0007157 43 16 1,000 2,298E-04 6,528E-03 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 2,298E-04 6,453E-03 ! negative regulation of growth GO:0045926 168 85 2,000 2,385E-04 6,621E-03 ! regulation of protein transport GO:0051223 165 87 2,000 2,554E-04 7,012E-03 GO:0070201|regulation of establishment of protein localization, ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 2,602E-04 7,063E-03 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 2,925E-04 7,852E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 2,925E-04 7,766E-03 ! regulation of cell adhesion GO:0030155 241 92 2,000 3,012E-04 7,911E-03 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 3,266E-04 8,488E-03 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 3,266E-04 8,398E-03 ! regulation of protein localization GO:0032880 188 97 2,000 3,518E-04 8,953E-03 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,625E-04 9,131E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,625E-04 9,038E-03 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 3,625E-04 8,946E-03 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 3,625E-04 8,857E-03 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 1,000 3,625E-04 8,769E-03 ! regulation of cell killing GO:0031341 46 21 1,000 4,003E-04 9,589E-03 ! regulation of vasoconstriction GO:0019229 40 21 1,000 4,003E-04 9,496E-03 ! inactivation of MAPK activity GO:0000188 45 22 1,000 4,4E-04 0,01033548 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 4,4E-04 0,01023705 ! peptidyl-serine modification GO:0018209 50 22 1,000 4,4E-04 0,01014048 ! positive regulation of B cell activation GO:0050871 42 22 1,000 4,4E-04 0,0100457 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 4,815E-04 0,01089077 GO:0010810|regulation of cell-substrate adhesion, ! vesicle targeting GO:0006903 49 23 1,000 4,815E-04 0,01079085 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,248E-04 0,01165434 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 5,248E-04 0,01154935 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 5,248E-04 0,01144623 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 5,248E-04 0,01134493 ! membrane depolarization GO:0051899 45 24 1,000 5,248E-04 0,01124542 ! oogenesis GO:0048477 44 24 1,000 5,248E-04 0,01114763 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 5,248E-04 0,01105153 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 5,248E-04 0,01095707 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 5,699E-04 0,01179832 ! leukocyte adhesion GO:0007159 55 25 1,000 5,699E-04 0,01169917 ! vasculogenesis GO:0001570 49 25 1,000 5,699E-04 0,01160168 ! interaction with host GO:0051701 66 25 1,000 5,699E-04 0,0115058 ! initiation of viral infection GO:0019059 60 26 1,000 6,168E-04 0,01235134 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 6,168E-04 0,01225092 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 6,168E-04 0,01215212 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 6,168E-04 0,01205491 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 6,168E-04 0,01195923 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 6,168E-04 0,01186507 ! regulation of blood coagulation GO:0030193 46 26 1,000 6,168E-04 0,01177237 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 6,168E-04 0,01168111 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 6,656E-04 0,01250731 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 7,161E-04 0,01335459 ! protein amino acid acylation GO:0043543 59 28 1,000 7,161E-04 0,01325341 ! vesicle docking GO:0048278 55 28 1,000 7,161E-04 0,01315376 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 7,685E-04 0,01401009 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 8,226E-04 0,01488624 ! regulation of B cell activation GO:0050864 55 30 1,000 8,226E-04 0,01477678 ! regulation of coagulation GO:0050818 52 30 1,000 8,226E-04 0,01466892 ! erythrocyte differentiation GO:0030218 62 31 1,000 8,786E-04 0,01555296 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 8,786E-04 0,01544107 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 8,786E-04 0,01533078 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 9,363E-04 0,01622227 ! cholesterol homeostasis GO:0042632 60 33 1,000 9,958E-04 0,01713186 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 9,958E-04 0,01701206 ! establishment of vesicle localization GO:0051650 67 33 1,000 9,958E-04 0,01689392 ! cholesterol transport GO:0030301 62 34 1,000 1,057E-03 0,01780999 ! cell fate specification GO:0001708 56 34 1,000 1,057E-03 0,01768801 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 1,057E-03 0,01756768 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 1,057E-03 0,01744898 ! sterol transport GO:0015918 63 35 1,000 1,12E-03 0,01836579 ! calcium-mediated signaling GO:0019722 67 35 1,000 1,12E-03 0,01824335 ! vesicle localization GO:0051648 70 35 1,000 1,12E-03 0,01812253 ! tissue remodeling GO:0048771 78 37 1,000 1,252E-03 0,02011544 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 1,252E-03 0,01998397 ! regulation of microtubule-based process GO:0032886 86 37 1,000 1,252E-03 0,0198542 ! neutral lipid metabolic process GO:0006638 54 38 1,000 1,32E-03 0,02080332 GO:0006639|acylglycerol metabolic process, ! glycogen metabolic process GO:0005977 63 38 1,000 1,32E-03 0,02066996 ! erythrocyte homeostasis GO:0034101 75 39 1,000 1,39E-03 0,02162906 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 1,39E-03 0,02149217 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 1,39E-03 0,021357 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 1,462E-03 0,0223205 ! lipid homeostasis GO:0055088 75 40 1,000 1,462E-03 0,02218186 ! glycerol ether metabolic process GO:0006662 57 40 1,000 1,462E-03 0,02204493 ! gliogenesis GO:0042063 91 41 1,000 1,535E-03 0,0230126 ! organic ether metabolic process GO:0018904 59 42 1,000 1,611E-03 0,02399435 ! striated muscle cell differentiation GO:0051146 91 43 1,000 1,688E-03 0,02498985 ! energy reserve metabolic process GO:0006112 76 44 1,000 1,767E-03 0,02599879 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 1,847E-03 0,02702086 ! female gamete generation GO:0007292 71 45 1,000 1,847E-03 0,02686002 ! leukocyte migration GO:0050900 75 46 1,000 1,929E-03 0,02788974 ! cell growth GO:0016049 90 46 1,000 1,929E-03 0,02772568 ! positive regulation of cell cycle GO:0045787 96 48 1,000 2,099E-03 0,02998642 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 2,099E-03 0,02981208 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 2,186E-03 0,03087332 ! regulation of ossification GO:0030278 123 50 1,000 2,275E-03 0,03194622 ! viral infectious cycle GO:0019058 104 51 1,000 2,366E-03 0,03303051 ! histone modification GO:0016570 104 52 1,000 2,459E-03 0,03412594 ! vesicle organization GO:0016050 127 53 1,000 2,553E-03 0,03523225 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 2,553E-03 0,03503431 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! activation of phospholipase C activity GO:0007202 110 54 1,000 2,648E-03 0,03614612 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 2,648E-03 0,03594531 ! membrane fusion GO:0006944 122 54 1,000 2,648E-03 0,03574671 ! covalent chromatin modification GO:0016569 115 54 1,000 2,648E-03 0,0355503 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 2,746E-03 0,03665735 ! cell maturation GO:0048469 107 55 1,000 2,746E-03 0,03645813 ! regulation of protein polymerization GO:0032271 117 55 1,000 2,746E-03 0,03626106 ! regulation of bone remodeling GO:0046850 143 57 1,000 2,946E-03 0,03869253 ! regulation of phospholipase activity GO:0010517 113 57 1,000 2,946E-03 0,03848562 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 3,048E-03 0,03961257 ! regulation of tissue remodeling GO:0034103 146 58 1,000 3,048E-03 0,03940298 ! positive regulation of organelle organization GO:0010638 108 58 1,000 3,048E-03 0,0391956 ! positive regulation of lipase activity GO:0060193 115 58 1,000 3,048E-03 0,03899038 ! establishment of organelle localization GO:0051656 122 59 1,000 3,153E-03 0,04011231 ! viral reproductive process GO:0022415 132 62 1,000 3,475E-03 0,04398411 ! regulation of homeostatic process GO:0032844 148 62 1,000 3,475E-03 0,04375739 ! regulation of protein complex assembly GO:0043254 132 63 1,000 3,586E-03 0,04492005 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 3,698E-03 0,0460912 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 3,812E-03 0,04727067 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 3,927E-03 0,04845826 ! myeloid cell differentiation GO:0030099 126 67 1,000 4,045E-03 0,0496538 ! viral reproduction GO:0016032 142 68 1,000 4,163E-03 0,05085712 ! regulation of lipase activity GO:0060191 137 68 1,000 4,163E-03 0,0506041 ! adaptive immune response GO:0002250 126 68 1,000 4,163E-03 0,05035358 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! lung development GO:0030324 165 69 1,000 4,284E-03 0,05155505 ! homeostasis of number of cells GO:0048872 131 69 1,000 4,284E-03 0,05130233 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 4,284E-03 0,05105207 ! developmental maturation GO:0021700 128 69 1,000 4,284E-03 0,05080425 ! germ cell development GO:0007281 133 70 1,000 4,406E-03 0,05199927 ! cell cycle checkpoint GO:0000075 145 71 1,000 4,53E-03 0,05320161 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 4,53E-03 0,05294706 ! respiratory tube development GO:0030323 171 72 1,000 4,655E-03 0,05415201 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 4,655E-03 0,05389537 ! regulation of immune effector process GO:0002697 156 73 1,000 4,782E-03 0,05510283 ! regulation of caspase activity GO:0043281 136 74 1,000 4,91E-03 0,05631716 ! respiratory system development GO:0060541 175 74 1,000 4,91E-03 0,056054 ! organelle localization GO:0051640 155 74 1,000 4,91E-03 0,05579328 ! leukocyte mediated immunity GO:0002443 136 75 1,000 5,04E-03 0,05700546 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 5,305E-03 0,05972343 ! antigen processing and presentation GO:0019882 117 78 1,000 5,44E-03 0,06095938 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 5,44E-03 0,06068102 ! meiosis GO:0007126 143 81 1,000 5,853E-03 0,06499782 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 5,853E-03 0,06470372 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 5,853E-03 0,06441226 ! meiotic cell cycle GO:0051321 144 82 1,000 5,994E-03 0,06566776 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 6,137E-03 0,06692892 GO:0045937|positive regulation of phosphate metabolic process, ! T cell activation GO:0042110 189 84 1,000 6,281E-03 0,06819562 ! positive regulation of cell activation GO:0050867 161 86 1,000 6,574E-03 0,0710582 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 7,014E-03 0,07548729 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 7,014E-03 0,07515621 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 7,014E-03 0,07482801 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 7,014E-03 0,07450267 ! positive regulation of helicase activity GO:0051096 12 5 0,000 7,014E-03 0,07418015 ! neuron fate determination GO:0048664 7 5 0,000 7,014E-03 0,07386041 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 7,014E-03 0,07354341 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 7,014E-03 0,07322912 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 7,014E-03 0,07291751 ! polyol transport GO:0015791 12 5 0,000 7,014E-03 0,07260854 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 7,014E-03 0,07230217 ! response to superoxide GO:0000303 10 5 0,000 7,014E-03 0,07199838 ! negative regulation of bone resorption GO:0045779 10 5 0,000 7,014E-03 0,07169713 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 7,014E-03 0,0713984 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 7,014E-03 0,07110214 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 7,014E-03 0,07080833 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 7,014E-03 0,07051693 ! hypothalamus development GO:0021854 9 5 0,000 7,014E-03 0,07022793 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 7,014E-03 0,06994129 ! cobalt ion transport GO:0006824 11 5 0,000 7,014E-03 0,06965697 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 7,014E-03 0,06937496 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 7,014E-03 0,06909522 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 7,014E-03 0,06881773 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 7,014E-03 0,06854246 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 7,014E-03 0,06826938 ! embryonic camera-type eye development GO:0031076 12 5 0,000 7,014E-03 0,06799847 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 7,014E-03 0,0677297 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 7,014E-03 0,06746305 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 7,014E-03 0,06719849 ! transposition GO:0032196 9 5 0,000 7,014E-03 0,066936 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 7,014E-03 0,06667554 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 7,014E-03 0,06641711 ! negative chemotaxis GO:0050919 16 5 0,000 7,014E-03 0,06616068 ! positive regulation of histone modification GO:0031058 6 5 0,000 7,014E-03 0,06590621 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 7,014E-03 0,0656537 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 7,014E-03 0,06540311 ! behavioral response to pain GO:0048266 10 5 0,000 7,014E-03 0,06515443 ! clathrin coat assembly GO:0048268 15 5 0,000 7,014E-03 0,06490763 ! Notch receptor processing GO:0007220 11 5 0,000 7,014E-03 0,0646627 ! regulation of dopamine uptake GO:0051584 9 5 0,000 7,014E-03 0,06441961 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 7,014E-03 0,06417833 ! micturition GO:0060073 9 5 0,000 7,014E-03 0,06393886 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 7,014E-03 0,06370117 ! copulation GO:0007620 9 5 0,000 7,014E-03 0,06346524 ! glial cell fate commitment GO:0021781 14 5 0,000 7,014E-03 0,06323105 ! protein maturation by protein folding GO:0022417 14 5 0,000 7,014E-03 0,06299858 ! bioluminescence GO:0008218 9 5 0,000 7,014E-03 0,06276782 ! spermidine metabolic process GO:0008216 7 5 0,000 7,014E-03 0,06253874 ! regulation of potassium ion transport GO:0043266 10 5 0,000 7,014E-03 0,06231133 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 7,014E-03 0,06208556 ! apoptotic cell clearance GO:0043277 23 5 0,000 7,014E-03 0,06186143 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 7,014E-03 0,0616389 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 7,014E-03 0,06141797 ! lipoprotein particle clearance GO:0034381 10 5 0,000 7,014E-03 0,06119862 ! grooming behavior GO:0007625 6 5 0,000 7,014E-03 0,06098084 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 7,014E-03 0,06076459 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 7,014E-03 0,06054988 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 7,014E-03 0,06033667 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 7,014E-03 0,06012496 ! response to protozoan GO:0001562 13 5 0,000 7,014E-03 0,05991474 ! positive regulation of glycolysis GO:0045821 13 5 0,000 7,014E-03 0,05970598 ! lymph vessel development GO:0001945 10 5 0,000 7,014E-03 0,05949866 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 7,014E-03 0,05929279 ! endochondral ossification GO:0001958 17 5 0,000 7,014E-03 0,05908833 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 7,014E-03 0,05888527 ! single strand break repair GO:0000012 8 5 0,000 7,014E-03 0,05868361 ! parathyroid gland development GO:0060017 14 5 0,000 7,014E-03 0,05848333 ! anagen GO:0042640 7 5 0,000 7,014E-03 0,0582844 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 7,014E-03 0,05808683 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 7,014E-03 0,05789059 ! cytokine secretion GO:0050663 15 5 0,000 7,014E-03 0,05769567 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 7,014E-03 0,05750206 ! ceramide catabolic process GO:0046514 7 5 0,000 7,014E-03 0,05730975 ! skeletal myofibril assembly GO:0014866 12 5 0,000 7,014E-03 0,05711872 ! smooth muscle tissue development GO:0048745 32 5 0,000 7,014E-03 0,05692895 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 7,014E-03 0,05674045 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 7,014E-03 0,05655318 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 7,014E-03 0,05636715 ! cardiac muscle fiber development GO:0048739 12 5 0,000 7,014E-03 0,05618234 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 7,014E-03 0,05599874 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 7,014E-03 0,05581634 ! neutrophil mediated immunity GO:0002446 7 5 0,000 7,014E-03 0,05563511 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 7,014E-03 0,05545506 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 7,014E-03 0,05527618 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 7,014E-03 0,05509844 ! glycine biosynthetic process GO:0006545 7 5 0,000 7,014E-03 0,05492184 ! microvillus organization GO:0032528 8 5 0,000 7,014E-03 0,05474637 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 7,014E-03 0,05457202 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 7,014E-03 0,05439878 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 7,014E-03 0,05422663 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 7,014E-03 0,05405557 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 7,014E-03 0,05388558 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 7,014E-03 0,05371666 ! polyol catabolic process GO:0046174 9 5 0,000 7,014E-03 0,0535488 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 7,014E-03 0,05338198 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 7,014E-03 0,0532162 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 7,014E-03 0,05305144 ! muscle cell migration GO:0014812 8 5 0,000 7,014E-03 0,0528877 ! mitochondrial fission GO:0000266 8 5 0,000 7,014E-03 0,05272497 ! sister chromatid cohesion GO:0007062 15 5 0,000 7,014E-03 0,05256324 ! response to tumor necrosis factor GO:0034612 10 5 0,000 7,014E-03 0,05240249 ! mRNA transcription GO:0009299 10 5 0,000 7,014E-03 0,05224273 ! nerve growth factor processing GO:0032455 9 5 0,000 7,014E-03 0,05208394 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 7,014E-03 0,05192611 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 7,014E-03 0,05176923 ! anaerobic glycolysis GO:0019642 6 5 0,000 7,014E-03 0,0516133 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 7,014E-03 0,0514583 ! monocyte activation GO:0042117 10 5 0,000 7,014E-03 0,05130424 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 7,014E-03 0,05115109 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 7,014E-03 0,05099885 ! response to food GO:0032094 6 5 0,000 7,014E-03 0,05084752 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 7,014E-03 0,05069709 ! positive regulation of transporter activity GO:0032411 8 5 0,000 7,014E-03 0,05054754 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 7,014E-03 0,05039887 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 7,014E-03 0,05025107 ! forebrain neuron development GO:0021884 13 5 0,000 7,014E-03 0,05010414 ! lipoprotein catabolic process GO:0042159 11 5 0,000 7,014E-03 0,04995806 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 7,014E-03 0,04981283 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 7,014E-03 0,04966845 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 7,014E-03 0,0495249 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 7,014E-03 0,04938218 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 7,014E-03 0,04924027 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 7,014E-03 0,04909918 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 7,014E-03 0,0489589 ! lipid glycosylation GO:0030259 7 5 0,000 7,014E-03 0,04881942 ! nucleobase transport GO:0015851 6 5 0,000 7,014E-03 0,04868072 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 7,014E-03 0,04854282 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 7,014E-03 0,04840569 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 7,014E-03 0,04826934 ! basic amino acid transport GO:0015802 12 5 0,000 7,014E-03 0,04813375 ! cellular glucose homeostasis GO:0001678 6 5 0,000 7,014E-03 0,04799892 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 7,014E-03 0,04786485 ! actin nucleation GO:0045010 11 5 0,000 7,014E-03 0,04773152 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 7,014E-03 0,04759893 ! depurination GO:0045007 5 5 0,000 7,014E-03 0,04746708 ! depyrimidination GO:0045008 10 5 0,000 7,014E-03 0,04733595 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 7,014E-03 0,04720555 ! regulation of centrosome cycle GO:0046605 7 5 0,000 7,014E-03 0,04707587 ! G2/M transition checkpoint GO:0031576 8 5 0,000 7,014E-03 0,04694689 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 7,014E-03 0,04681862 ! zinc ion homeostasis GO:0055069 9 5 0,000 7,014E-03 0,04669105 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 7,014E-03 0,04656417 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 7,014E-03 0,04643798 ! forebrain morphogenesis GO:0048853 13 5 0,000 7,014E-03 0,04631247 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 7,014E-03 0,04618764 ! activated T cell proliferation GO:0050798 16 5 0,000 7,014E-03 0,04606348 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 7,014E-03 0,04593999 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 7,014E-03 0,04581715 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 7,014E-03 0,04569497 ! positive regulation of organ growth GO:0046622 6 5 0,000 7,014E-03 0,04557344 ! gamma-delta T cell activation GO:0046629 6 5 0,000 7,014E-03 0,04545256 ! response to arsenic GO:0046685 11 5 0,000 7,014E-03 0,04533231 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 7,014E-03 0,0452127 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 7,014E-03 0,04509372 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 7,014E-03 0,04497537 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 7,014E-03 0,04485763 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 7,014E-03 0,04474051 ! response to mercury ion GO:0046689 8 5 0,000 7,014E-03 0,044624 ! response to cadmium ion GO:0046686 7 5 0,000 7,014E-03 0,04450809 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 7,014E-03 0,04439278 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 7,014E-03 0,04427807 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 7,014E-03 0,04416396 ! bile acid biosynthetic process GO:0006699 7 5 0,000 7,014E-03 0,04405042 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 7,014E-03 0,04393747 ! ganglioside catabolic process GO:0006689 12 5 0,000 7,014E-03 0,0438251 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 7,014E-03 0,0437133 ! decidualization GO:0046697 11 5 0,000 7,014E-03 0,04360207 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 7,014E-03 0,04349141 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 7,014E-03 0,0433813 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 7,014E-03 0,04327175 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 7,014E-03 0,04316276 ! embryonic cleavage GO:0040016 6 5 0,000 7,014E-03 0,04305431 ! peroxisome fission GO:0016559 5 5 0,000 7,014E-03 0,0429464 ! histone demethylation GO:0016577 13 5 0,000 7,014E-03 0,04283904 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 7,014E-03 0,04273221 ! mitotic recombination GO:0006312 9 5 0,000 7,014E-03 0,04262591 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 7,014E-03 0,04252014 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 7,014E-03 0,04241489 ! metaphase plate congression GO:0051310 7 5 0,000 7,014E-03 0,04231016 ! regulation of sterol transport GO:0032371 7 5 0,000 7,014E-03 0,04220595 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 7,014E-03 0,04210225 ! enteric nervous system development GO:0048484 8 5 0,000 7,014E-03 0,04199906 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 7,014E-03 0,04189637 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 7,014E-03 0,04179418 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 7,014E-03 0,04169249 ! muscle cell proliferation GO:0033002 12 5 0,000 7,014E-03 0,0415913 ! skeletal muscle regeneration GO:0043403 8 5 0,000 7,014E-03 0,04149059 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 7,014E-03 0,04139037 ! B cell homeostasis GO:0001782 13 5 0,000 7,014E-03 0,04129064 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 7,014E-03 0,04119138 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 7,014E-03 0,0410926 ! metaphase GO:0051323 11 5 0,000 7,014E-03 0,04099429 ! melatonin biosynthetic process GO:0030187 7 5 0,000 7,014E-03 0,04089646 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 7,014E-03 0,04079908 ! cellular response to nutrient GO:0031670 8 5 0,000 7,014E-03 0,04070217 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 7,014E-03 0,04060572 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 7,014E-03 0,04050973 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 7,014E-03 0,04041419 ! regulation of hair follicle development GO:0051797 10 5 0,000 7,014E-03 0,04031909 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 7,014E-03 0,04022445 ! response to redox state GO:0051775 6 5 0,000 7,014E-03 0,04013025 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 7,014E-03 0,04003648 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 7,014E-03 0,03994316 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 7,014E-03 0,03985027 ! brown fat cell differentiation GO:0050873 7 5 0,000 7,014E-03 0,03975781 ! regulation of telomerase activity GO:0051972 7 5 0,000 7,014E-03 0,03966578 ! galactolipid metabolic process GO:0019374 7 5 0,000 7,014E-03 0,03957417 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 7,014E-03 0,03948298 ! porphyrin catabolic process GO:0006787 12 5 0,000 7,014E-03 0,03939222 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 7,014E-03 0,03930187 ! striatum development GO:0021756 14 5 0,000 7,014E-03 0,03921193 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 7,014E-03 0,03912241 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 7,014E-03 0,03903329 ! glial cell migration GO:0008347 10 5 0,000 7,014E-03 0,03894458 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 7,014E-03 0,03885627 ! neural plate morphogenesis GO:0001839 7 5 0,000 7,014E-03 0,03876836 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 7,014E-03 0,03868085 ! somatic stem cell maintenance GO:0035019 15 5 0,000 7,014E-03 0,03859373 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 7,014E-03 0,038507 ! negative regulation of lipase activity GO:0060192 8 5 0,000 7,014E-03 0,03842066 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 7,014E-03 0,03833471 ! neuroprotection GO:0043526 8 5 0,000 7,014E-03 0,03824914 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 7,014E-03 0,03816395 ! regulation of sensory perception GO:0051931 8 5 0,000 7,014E-03 0,03807914 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 7,014E-03 0,03799471 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 7,014E-03 0,03791065 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 7,014E-03 0,03782696 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 7,014E-03 0,03774365 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 7,014E-03 0,03766069 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 7,014E-03 0,0375781 ! sequestering of calcium ion GO:0051208 7 5 0,000 7,014E-03 0,03749588 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 7,014E-03 0,03741401 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 7,014E-03 0,03733249 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 7,014E-03 0,03725134 ! spindle assembly GO:0051225 6 5 0,000 7,014E-03 0,03717053 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 7,014E-03 0,03709008 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 7,014E-03 0,03700997 ! protein palmitoylation GO:0018345 12 5 0,000 7,014E-03 0,0369302 ! drug metabolic process GO:0017144 7 5 0,000 7,014E-03 0,03685078 ! stem cell division GO:0017145 11 5 0,000 7,014E-03 0,03677171 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 7,014E-03 0,03669297 ! organ regeneration GO:0031100 7 5 0,000 7,014E-03 0,03661456 ! carnitine metabolic process GO:0009437 8 5 0,000 7,014E-03 0,03653649 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 7,014E-03 0,03645876 ! ossification GO:0001503 205 91 1,000 7,332E-03 0,03803014 ! gland development GO:0048732 220 91 1,000 7,332E-03 0,03794957 ! bone development GO:0060348 206 92 1,000 7,488E-03 0,03867631 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 7,646E-03 0,03940774 ! regulation of membrane potential GO:0042391 179 94 1,000 7,805E-03 0,04014379 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 7,966E-03 0,04088442 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 8,411E-03 0,04307878 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 8,411E-03 0,04298865 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 8,411E-03 0,04289891 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 8,411E-03 0,04280953 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 8,411E-03 0,04272053 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 8,411E-03 0,0426319 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 8,411E-03 0,04254364 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 8,411E-03 0,04245574 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 8,411E-03 0,0423682 ! response to oxygen radical GO:0000305 11 6 0,000 8,411E-03 0,04228102 ! positive regulation of axon extension GO:0045773 13 6 0,000 8,411E-03 0,0421942 ! myoblast cell fate commitment GO:0048625 18 6 0,000 8,411E-03 0,04210774 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 8,411E-03 0,04202163 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 8,411E-03 0,04193587 ! regulation of interferon-beta production GO:0032648 8 6 0,000 8,411E-03 0,04185046 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 8,411E-03 0,0417654 ! forebrain regionalization GO:0021871 9 6 0,000 8,411E-03 0,04168068 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 8,411E-03 0,04159631 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 8,411E-03 0,04151227 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 8,411E-03 0,04142858 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 8,411E-03 0,04134522 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 8,411E-03 0,0412622 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 8,411E-03 0,04117951 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 8,411E-03 0,04109715 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 8,411E-03 0,04101512 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 8,411E-03 0,04093342 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 8,411E-03 0,04085204 ! malate metabolic process GO:0006108 13 6 0,000 8,411E-03 0,04077098 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 8,411E-03 0,04069025 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 8,411E-03 0,04060983 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 8,411E-03 0,04052974 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 8,411E-03 0,04044995 ! protein refolding GO:0042026 15 6 0,000 8,411E-03 0,04037048 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 8,411E-03 0,04029133 ! opsonization GO:0008228 8 6 0,000 8,411E-03 0,04021248 ! mating behavior GO:0007617 7 6 0,000 8,411E-03 0,04013394 ! erythrocyte maturation GO:0043249 8 6 0,000 8,411E-03 0,0400557 ! embryonic hemopoiesis GO:0035162 16 6 0,000 8,411E-03 0,03997777 ! protein amino acid dealkylation GO:0008214 15 6 0,000 8,411E-03 0,03990015 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 8,411E-03 0,03982282 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 8,411E-03 0,03974579 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 8,411E-03 0,03966907 ! response to interferon-gamma GO:0034341 16 6 0,000 8,411E-03 0,03959263 ! toxin metabolic process GO:0009404 11 6 0,000 8,411E-03 0,03951649 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 8,411E-03 0,03944064 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 8,411E-03 0,03936509 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 8,411E-03 0,03928982 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 8,411E-03 0,03921484 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 8,411E-03 0,03914014 ! cGMP-mediated signaling GO:0019934 14 6 0,000 8,411E-03 0,03906573 ! dorsal spinal cord development GO:0021516 10 6 0,000 8,411E-03 0,03899161 ! activation of MAPKKK activity GO:0000185 12 6 0,000 8,411E-03 0,03891776 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 8,411E-03 0,03884419 ! thymic T cell selection GO:0045061 16 6 0,000 8,411E-03 0,0387709 ! sphingoid catabolic process GO:0046521 8 6 0,000 8,411E-03 0,03869788 ! protein lipoylation GO:0009249 10 6 0,000 8,411E-03 0,03862514 ! transepithelial chloride transport GO:0030321 12 6 0,000 8,411E-03 0,03855268 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 8,411E-03 0,03848048 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 8,411E-03 0,03840855 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 8,411E-03 0,0383369 ! glutamate catabolic process GO:0006538 12 6 0,000 8,411E-03 0,0382655 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 8,411E-03 0,03819438 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 8,411E-03 0,03812352 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 8,411E-03 0,03805292 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 8,411E-03 0,03798258 ! hyperosmotic response GO:0006972 10 6 0,000 8,411E-03 0,0379125 ! L-serine biosynthetic process GO:0006564 7 6 0,000 8,411E-03 0,03784268 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 8,411E-03 0,03777312 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 8,411E-03 0,03770381 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 8,411E-03 0,03763475 ! urea metabolic process GO:0019627 7 6 0,000 8,411E-03 0,03756595 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 8,411E-03 0,0374974 ! neutrophil activation GO:0042119 7 6 0,000 8,411E-03 0,0374291 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 8,411E-03 0,03736105 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 8,411E-03 0,03729324 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 8,411E-03 0,03722568 ! paraxial mesoderm development GO:0048339 16 6 0,000 8,411E-03 0,03715837 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 8,411E-03 0,03709129 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 8,411E-03 0,03702446 ! neuron apoptosis GO:0051402 15 6 0,000 8,411E-03 0,03695787 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 8,411E-03 0,03689152 ! negative regulation of platelet activation GO:0010544 9 6 0,000 8,411E-03 0,0368254 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 8,411E-03 0,03675953 ! carnitine transport GO:0015879 10 6 0,000 8,411E-03 0,03669389 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 8,411E-03 0,03662848 ! positive regulation of exocytosis GO:0045921 11 6 0,000 8,411E-03 0,0365633 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 8,411E-03 0,03649836 ! early endosome to late endosome transport GO:0045022 16 6 0,000 8,411E-03 0,03643365 ! 5S class rRNA transcription GO:0042791 13 6 0,000 8,411E-03 0,03636916 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 8,411E-03 0,0363049 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 8,411E-03 0,03624087 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 8,411E-03 0,03617707 ! sodium ion homeostasis GO:0055078 12 6 0,000 8,411E-03 0,03611349 ! establishment of spindle localization GO:0051293 16 6 0,000 8,411E-03 0,03605013 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 8,411E-03 0,035987 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 8,411E-03 0,03592408 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 8,411E-03 0,03586139 ! response to UV-C GO:0010225 14 6 0,000 8,411E-03 0,03579891 ! astrocyte development GO:0014002 16 6 0,000 8,411E-03 0,03573665 ! protein targeting to lysosome GO:0006622 12 6 0,000 8,411E-03 0,03567461 ! purine base biosynthetic process GO:0009113 17 6 0,000 8,411E-03 0,03561278 ! regulation of dendrite development GO:0050773 16 6 0,000 8,411E-03 0,03555117 ! peptidyl-arginine modification GO:0018195 13 6 0,000 8,411E-03 0,03548977 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 8,411E-03 0,03542858 ! response to copper ion GO:0046688 10 6 0,000 8,411E-03 0,0353676 ! response to exogenous dsRNA GO:0043330 13 6 0,000 8,411E-03 0,03530683 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 8,411E-03 0,03524627 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 8,411E-03 0,03518592 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 8,411E-03 0,03512577 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 8,411E-03 0,03506583 ! regulation of dopamine secretion GO:0014059 14 6 0,000 8,411E-03 0,03500609 ! nucleoside catabolic process GO:0009164 10 6 0,000 8,411E-03 0,03494656 ! hair follicle maturation GO:0048820 8 6 0,000 8,411E-03 0,03488723 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 8,411E-03 0,03482809 ! Schwann cell development GO:0014044 15 6 0,000 8,411E-03 0,03476916 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 8,411E-03 0,03471043 ! response to pheromone GO:0019236 6 6 0,000 8,411E-03 0,0346519 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 8,411E-03 0,03459356 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 8,411E-03 0,03453542 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 8,411E-03 0,03447748 ! base conversion or substitution editing GO:0016553 6 6 0,000 8,411E-03 0,03441973 ! subpallium development GO:0021544 15 6 0,000 8,411E-03 0,03436217 ! neural tube patterning GO:0021532 8 6 0,000 8,411E-03 0,0343048 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 8,411E-03 0,03424763 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 8,411E-03 0,03419064 ! maintenance of organ identity GO:0048496 9 6 0,000 8,411E-03 0,03413385 ! G2 phase GO:0051319 16 6 0,000 8,411E-03 0,03407724 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 8,411E-03 0,03402082 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 8,411E-03 0,03396459 ! oxygen homeostasis GO:0032364 10 6 0,000 8,411E-03 0,03390854 ! establishment of planar polarity GO:0001736 7 6 0,000 8,411E-03 0,03385268 ! regulation of mast cell activation GO:0033003 13 6 0,000 8,411E-03 0,033797 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 8,411E-03 0,0337415 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 8,411E-03 0,03368619 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 8,411E-03 0,03363106 ! receptor internalization GO:0031623 11 6 0,000 8,411E-03 0,0335761 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 8,411E-03 0,03352133 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 8,411E-03 0,03346674 ! neutrophil homeostasis GO:0001780 11 6 0,000 8,411E-03 0,03341232 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 8,411E-03 0,03335808 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 8,411E-03 0,03330401 ! protein deubiquitination GO:0016579 16 6 0,000 8,411E-03 0,03325012 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 8,411E-03 0,03319641 ! protein destabilization GO:0031648 9 6 0,000 8,411E-03 0,03314286 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 8,411E-03 0,03308949 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 8,411E-03 0,0330363 ! regulation of viral transcription GO:0046782 11 6 0,000 8,411E-03 0,03298327 ! progesterone metabolic process GO:0042448 12 6 0,000 8,411E-03 0,03293041 ! negative regulation of axon extension GO:0030517 24 6 0,000 8,411E-03 0,03287772 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 8,411E-03 0,0328252 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 8,411E-03 0,03277285 ! triglyceride catabolic process GO:0019433 10 6 0,000 8,411E-03 0,03272066 ! determination of adult lifespan GO:0008340 17 6 0,000 8,411E-03 0,03266864 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 8,411E-03 0,03261679 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 8,411E-03 0,0325651 ! neural plate development GO:0001840 9 6 0,000 8,411E-03 0,03251357 ! catecholamine transport GO:0051937 9 6 0,000 8,411E-03 0,03246221 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 8,411E-03 0,032411 ! sensory cilium assembly GO:0035058 10 6 0,000 8,411E-03 0,03235996 ! organ or tissue specific immune response GO:0002251 8 6 0,000 8,411E-03 0,03230908 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 8,411E-03 0,03225836 ! maternal placenta development GO:0001893 12 6 0,000 8,411E-03 0,0322078 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 8,411E-03 0,0321574 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 8,411E-03 0,03210715 ! negative regulation of B cell activation GO:0050869 14 6 0,000 8,411E-03 0,03205706 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 8,411E-03 0,03200713 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 8,411E-03 0,03195735 ! positive regulation of coagulation GO:0050820 13 6 0,000 8,411E-03 0,03190773 ! cellular anion homeostasis GO:0030002 11 6 0,000 8,411E-03 0,03185826 GO:0055081|anion homeostasis, ! skeletal muscle tissue development GO:0007519 223 100 1,000 8,792E-03 0,0332489 GO:0060538|skeletal muscle organ development, ! tRNA transcription GO:0009304 17 7 0,000 9,806E-03 0,03702756 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 9,806E-03 0,03697042 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 9,806E-03 0,03691345 ! behavioral response to cocaine GO:0048148 14 7 0,000 9,806E-03 0,03685666 ! regulation of helicase activity GO:0051095 16 7 0,000 9,806E-03 0,03680005 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 9,806E-03 0,03674361 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 9,806E-03 0,03668734 ! sleep GO:0030431 16 7 0,000 9,806E-03 0,03663124 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 9,806E-03 0,03657531 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 9,806E-03 0,03651956 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 9,806E-03 0,03646397 ! prostate gland development GO:0030850 14 7 0,000 9,806E-03 0,03640856 ! nucleotide-sugar transport GO:0015780 11 7 0,000 9,806E-03 0,03635331 ! synaptonemal complex assembly GO:0007130 10 7 0,000 9,806E-03 0,03629823 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 9,806E-03 0,03624331 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 9,806E-03 0,03618857 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 9,806E-03 0,03613398 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 9,806E-03 0,03607956 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 9,806E-03 0,03602531 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 9,806E-03 0,03597122 ! SMAD protein complex assembly GO:0007183 13 7 0,000 9,806E-03 0,03591729 ! glycolipid transport GO:0046836 11 7 0,000 9,806E-03 0,03586352 ! protein amino acid sulfation GO:0006477 10 7 0,000 9,806E-03 0,03580991 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 9,806E-03 0,03575646 ! establishment of tissue polarity GO:0007164 8 7 0,000 9,806E-03 0,03570318 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 9,806E-03 0,03565005 ! mRNA stabilization GO:0048255 18 7 0,000 9,806E-03 0,03559707 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 9,806E-03 0,03554426 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 9,806E-03 0,0354916 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 9,806E-03 0,0354391 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 9,806E-03 0,03538675 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 9,806E-03 0,03533456 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 9,806E-03 0,03528252 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 9,806E-03 0,03523063 ! lipoprotein transport GO:0042953 14 7 0,000 9,806E-03 0,0351789 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 9,806E-03 0,03512732 ! rhythmic behavior GO:0007622 17 7 0,000 9,806E-03 0,03507589 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 9,806E-03 0,03502461 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 9,806E-03 0,03497348 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 9,806E-03 0,03492249 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 9,806E-03 0,03487166 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 9,806E-03 0,03482098 ! regulation of odontogenesis GO:0042481 14 7 0,000 9,806E-03 0,03477044 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 9,806E-03 0,03472005 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 9,806E-03 0,0346698 ! mechanosensory behavior GO:0007638 16 7 0,000 9,806E-03 0,0346197 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 9,806E-03 0,03456974 ! positive regulation of isotype switching GO:0045830 17 7 0,000 9,806E-03 0,03451993 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 9,806E-03 0,03447026 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 9,806E-03 0,03442073 ! protein-cofactor linkage GO:0018065 13 7 0,000 9,806E-03 0,03437135 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 9,806E-03 0,03432211 ! spinal cord patterning GO:0021511 14 7 0,000 9,806E-03 0,03427301 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 9,806E-03 0,03422404 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 9,806E-03 0,03417522 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 9,806E-03 0,03412654 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 9,806E-03 0,034078 ! adrenal gland development GO:0030325 17 7 0,000 9,806E-03 0,03402959 ! cysteine metabolic process GO:0006534 13 7 0,000 9,806E-03 0,03398132 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 9,806E-03 0,03393319 ! ovulation GO:0030728 10 7 0,000 9,806E-03 0,03388519 ! adenohypophysis development GO:0021984 11 7 0,000 9,806E-03 0,03383733 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 9,806E-03 0,03378961 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 9,806E-03 0,03374202 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 9,806E-03 0,03369456 ! microtubule nucleation GO:0007020 21 7 0,000 9,806E-03 0,03364723 ! proline biosynthetic process GO:0006561 10 7 0,000 9,806E-03 0,03360004 ! tryptophan metabolic process GO:0006568 11 7 0,000 9,806E-03 0,03355298 ! thyroid hormone generation GO:0006590 13 7 0,000 9,806E-03 0,03350606 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 9,806E-03 0,03345926 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 9,806E-03 0,0334126 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 9,806E-03 0,03336606 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 9,806E-03 0,03331965 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 9,806E-03 0,03327338 ! galactose metabolic process GO:0006012 13 7 0,000 9,806E-03 0,03322723 ! response to dietary excess GO:0002021 8 7 0,000 9,806E-03 0,03318121 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 9,806E-03 0,03313531 ! intracellular pH reduction GO:0051452 13 7 0,000 9,806E-03 0,03308955 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 9,806E-03 0,0330439 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 9,806E-03 0,03299839 ! organ growth GO:0035265 15 7 0,000 9,806E-03 0,032953 ! nucleoside transport GO:0015858 11 7 0,000 9,806E-03 0,03290773 ! nucleoside salvage GO:0043174 11 7 0,000 9,806E-03 0,03286259 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 9,806E-03 0,03281758 ! male sex determination GO:0030238 15 7 0,000 9,806E-03 0,03277268 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 9,806E-03 0,03272791 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 9,806E-03 0,03268326 ! parturition GO:0007567 16 7 0,000 9,806E-03 0,03263873 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 9,806E-03 0,03259433 ! rRNA modification GO:0000154 14 7 0,000 9,806E-03 0,03255004 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 9,806E-03 0,03250588 ! spindle checkpoint GO:0031577 16 7 0,000 9,806E-03 0,03246183 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 9,806E-03 0,0324179 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 9,806E-03 0,0323741 ! monocyte differentiation GO:0030224 16 7 0,000 9,806E-03 0,03233041 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 9,806E-03 0,03228683 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 9,806E-03 0,03224338 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 9,806E-03 0,03220004 ! hyaluronan metabolic process GO:0030212 9 7 0,000 9,806E-03 0,03215682 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 9,806E-03 0,03211371 ! anterograde axon cargo transport GO:0008089 18 7 0,000 9,806E-03 0,03207072 ! fibrinolysis GO:0042730 11 7 0,000 9,806E-03 0,03202785 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 9,806E-03 0,03198509 ! skeletal muscle contraction GO:0003009 8 7 0,000 9,806E-03 0,03194244 ! eating behavior GO:0042755 8 7 0,000 9,806E-03 0,03189991 ! B cell lineage commitment GO:0002326 21 7 0,000 9,806E-03 0,03185749 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 9,806E-03 0,03181518 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 9,806E-03 0,03177299 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 9,806E-03 0,0317309 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 9,806E-03 0,03168893 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 9,806E-03 0,03164707 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 9,806E-03 0,03160532 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 9,806E-03 0,03156368 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 9,806E-03 0,03152215 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 9,806E-03 0,03148072 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 9,806E-03 0,03143941 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 9,806E-03 0,03139821 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 9,806E-03 0,03135711 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 9,806E-03 0,03131612 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 9,806E-03 0,03127524 ! histone ubiquitination GO:0016574 9 7 0,000 9,806E-03 0,03123446 ! regulation of meiosis GO:0040020 12 7 0,000 9,806E-03 0,03119379 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 9,806E-03 0,03115323 ! T cell lineage commitment GO:0002360 16 7 0,000 9,806E-03 0,03111277 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 9,806E-03 0,03107241 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 9,806E-03 0,03103216 ! transcription termination GO:0006353 14 7 0,000 9,806E-03 0,03099202 ! coenzyme A metabolic process GO:0015936 12 7 0,000 9,806E-03 0,03095198 ! anaphase GO:0051322 18 7 0,000 9,806E-03 0,03091204 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 9,806E-03 0,0308722 ! axonal fasciculation GO:0007413 19 7 0,000 9,806E-03 0,03083247 ! negative regulation of nuclear division GO:0051784 15 7 0,000 9,806E-03 0,03079284 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 9,806E-03 0,03075331 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 9,806E-03 0,03071389 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 9,806E-03 0,03067456 ! diuresis GO:0030146 12 7 0,000 9,806E-03 0,03063533 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 9,806E-03 0,03059621 ! thiamin metabolic process GO:0006772 7 7 0,000 9,806E-03 0,03055718 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 9,806E-03 0,03051826 ! antibiotic transport GO:0042891 9 7 0,000 9,806E-03 0,03047943 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 9,806E-03 0,0304407 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 9,806E-03 0,03040207 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 9,806E-03 0,03036354 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 9,806E-03 0,0303251 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 9,806E-03 0,03028676 ! melanin biosynthetic process GO:0042438 10 7 0,000 9,806E-03 0,03024852 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 9,806E-03 0,03021038 ! dopamine biosynthetic process GO:0042416 18 7 0,000 9,806E-03 0,03017233 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 9,806E-03 0,03013438 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 9,806E-03 0,03009652 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 9,806E-03 0,03005876 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 9,806E-03 0,03002109 ! endosome to lysosome transport GO:0008333 12 7 0,000 9,806E-03 0,02998352 ! protein modification by small protein removal GO:0070646 19 7 0,000 9,806E-03 0,02994604 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 9,806E-03 0,02990865 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 9,806E-03 0,02987136 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 9,806E-03 0,02983416 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 9,806E-03 0,02979705 ! muscle adaptation GO:0043500 13 7 0,000 9,806E-03 0,02976004 ! embryonic heart tube development GO:0035050 14 7 0,000 9,806E-03 0,02972312 ! retina homeostasis GO:0001895 12 7 0,000 9,806E-03 0,02968628 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 9,806E-03 0,02964954 ! protein amino acid prenylation GO:0018346 19 7 0,000 9,806E-03 0,02961289 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 9,806E-03 0,02957633 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,0111995 0,03373661 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,0111995 0,03369506 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,0111995 0,03365361 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,0111995 0,03361227 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,0111995 0,03357103 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0111995 0,03352989 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0111995 0,03348885 ! male meiosis GO:0007140 9 8 0,000 0,0111995 0,03344791 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,0111995 0,03340707 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,0111995 0,03336633 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,0111995 0,03332568 ! meiotic prophase I GO:0007128 14 8 0,000 0,0111995 0,03328514 ! response to zinc ion GO:0010043 12 8 0,000 0,0111995 0,0332447 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0111995 0,03320435 ! oligopeptide transport GO:0006857 16 8 0,000 0,0111995 0,03316411 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,0111995 0,03312395 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,0111995 0,0330839 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,0111995 0,03304395 ! signal peptide processing GO:0006465 12 8 0,000 0,0111995 0,03300409 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,0111995 0,03296432 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,0111995 0,03292465 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0111995 0,03288508 ! succinate metabolic process GO:0006105 17 8 0,000 0,0111995 0,0328456 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,0111995 0,03280622 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,0111995 0,03276693 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0111995 0,03272774 ! estrogen metabolic process GO:0008210 17 8 0,000 0,0111995 0,03268863 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,0111995 0,03264963 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0111995 0,03261071 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,0111995 0,03257189 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0111995 0,03253316 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0111995 0,03249452 ! reflex GO:0060004 17 8 0,000 0,0111995 0,03245597 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0111995 0,03241752 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,0111995 0,03237916 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,0111995 0,03234088 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0111995 0,0323027 ! pigment granule organization GO:0048753 17 8 0,000 0,0111995 0,03226461 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0111995 0,0322266 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,0111995 0,03218869 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,0111995 0,03215087 ! astrocyte differentiation GO:0048708 19 8 0,000 0,0111995 0,03211313 ! histidine catabolic process GO:0006548 10 8 0,000 0,0111995 0,03207548 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0111995 0,03203792 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,0111995 0,03200045 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,0111995 0,03196307 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,0111995 0,03192577 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,0111995 0,03188856 ! melanin metabolic process GO:0006582 17 8 0,000 0,0111995 0,03185144 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,0111995 0,0318144 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,0111995 0,03177745 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,0111995 0,03174059 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0111995 0,03170381 ! macrophage activation GO:0042116 13 8 0,000 0,0111995 0,03166711 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0111995 0,0316305 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0111995 0,03159398 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,0111995 0,03155754 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0111995 0,03152118 ! purine salvage GO:0043101 12 8 0,000 0,0111995 0,03148491 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,0111995 0,03144872 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0111995 0,03141261 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,0111995 0,03137659 ! osteoblast development GO:0002076 17 8 0,000 0,0111995 0,03134065 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,0111995 0,03130479 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,0111995 0,03126901 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,0111995 0,03123332 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,0111995 0,0311977 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0111995 0,03116217 ! response to UV-B GO:0010224 17 8 0,000 0,0111995 0,03112672 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,0111995 0,03109135 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0111995 0,03105606 ! intermediate filament organization GO:0045109 12 8 0,000 0,0111995 0,03102085 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,0111995 0,03098572 ! cellular extravasation GO:0045123 13 8 0,000 0,0111995 0,03095066 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,0111995 0,03091569 ! response to antibiotic GO:0046677 11 8 0,000 0,0111995 0,0308808 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,0111995 0,03084598 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,0111995 0,03081125 ! DNA topological change GO:0006265 12 8 0,000 0,0111995 0,03077659 ! response to tropane GO:0014073 15 8 0,000 0,0111995 0,03074201 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,0111995 0,0307075 ! melanosome transport GO:0032402 13 8 0,000 0,0111995 0,03067308 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 0,000 0,0111995 0,03063873 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,0111995 0,03060446 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0111995 0,03057026 ! mast cell activation GO:0045576 14 8 0,000 0,0111995 0,03053615 ! multicellular organismal aging GO:0010259 20 8 0,000 0,0111995 0,0305021 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,0111995 0,03046814 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,0111995 0,03043425 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,0111995 0,03040043 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,0111995 0,03036669 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0111995 0,03033302 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0111995 0,03029943 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,0111995 0,03026591 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0111995 0,03023247 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,0111995 0,0301991 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,0111995 0,03016581 ! intracellular lipid transport GO:0032365 16 8 0,000 0,0111995 0,03013258 ! response to tumor cell GO:0002347 16 8 0,000 0,0111995 0,03009944 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0111995 0,03006636 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,0111995 0,03003336 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,0111995 0,03000042 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,0111995 0,02996756 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0111995 0,02993478 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,0111995 0,02990206 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,0111995 0,02986942 ! hormone catabolic process GO:0042447 17 8 0,000 0,0111995 0,02983684 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,0111995 0,02980434 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,0111995 0,02977191 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,0111995 0,02973955 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,0111995 0,02970726 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0111995 0,02967504 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,0111995 0,02964289 ! adult feeding behavior GO:0008343 10 8 0,000 0,0111995 0,02961081 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,0111995 0,0295788 ! ATP catabolic process GO:0006200 11 8 0,000 0,0111995 0,02954685 ! blastocyst growth GO:0001832 19 8 0,000 0,0111995 0,02951498 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0111995 0,02948318 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0111995 0,02945144 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,0111995 0,02941977 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0111995 0,02938817 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,0111995 0,02935664 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,0111995 0,02932517 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,0111995 0,02929378 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,0111995 0,02926245 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,0111995 0,02923118 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,0111995 0,02919999 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0111995 0,02916886 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,0111995 0,02913779 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,0111995 0,02910679 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0111995 0,02907586 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,0111995 0,029045 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,0111995 0,0290142 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0111995 0,02898346 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,0111995 0,02895279 ! axon extension GO:0048675 16 9 0,000 0,01259077 0,03251506 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01259077 0,03248073 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01259077 0,03244647 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01259077 0,03241228 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01259077 0,03237816 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01259077 0,03234411 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01259077 0,03231014 ! reproductive behavior GO:0019098 22 9 0,000 0,01259077 0,03227623 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01259077 0,0322424 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01259077 0,03220864 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01259077 0,03217495 ! UTP metabolic process GO:0046051 10 9 0,000 0,01259077 0,03214133 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01259077 0,03210778 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01259077 0,0320743 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01259077 0,03204088 ! artery development GO:0060840 25 9 0,000 0,01259077 0,03200754 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01259077 0,03197427 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01259077 0,03194107 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01259077 0,03190793 ! equilibrioception GO:0050957 20 9 0,000 0,01259077 0,03187487 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01259077 0,03184187 ! chemosensory behavior GO:0007635 21 9 0,000 0,01259077 0,03180894 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01259077 0,03177608 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01259077 0,03174329 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01259077 0,03171057 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01259077 0,03167791 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01259077 0,03164532 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01259077 0,03161279 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01259077 0,03158034 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01259077 0,03154795 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01259077 0,03151562 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01259077 0,03148337 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01259077 0,03145118 ! protein targeting to ER GO:0045047 25 9 0,000 0,01259077 0,03141905 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01259077 0,03138699 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01259077 0,03135499 ! T cell selection GO:0045058 27 9 0,000 0,01259077 0,03132306 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,01259077 0,0312912 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01259077 0,0312594 ! glycine catabolic process GO:0006546 15 9 0,000 0,01259077 0,03122766 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01259077 0,03119599 ! endosome organization GO:0007032 20 9 0,000 0,01259077 0,03116439 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01259077 0,03113284 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01259077 0,03110136 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01259077 0,03106995 ! mannose metabolic process GO:0006013 13 9 0,000 0,01259077 0,0310386 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01259077 0,03100731 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01259077 0,03097608 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01259077 0,03094492 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01259077 0,03091382 ! receptor clustering GO:0043113 20 9 0,000 0,01259077 0,03088278 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01259077 0,0308518 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01259077 0,03082089 ! retinol metabolic process GO:0042572 20 9 0,000 0,01259077 0,03079004 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01259077 0,03075925 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01259077 0,03072852 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01259077 0,03069785 ! macrophage differentiation GO:0030225 15 9 0,000 0,01259077 0,03066725 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01259077 0,0306367 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01259077 0,03060622 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01259077 0,03057579 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01259077 0,03054543 ! response to amine stimulus GO:0014075 13 9 0,000 0,01259077 0,03051513 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01259077 0,03048489 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01259077 0,0304547 ! erythrocyte development GO:0048821 17 9 0,000 0,01259077 0,03042458 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01259077 0,03039452 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01259077 0,03036451 ! renal water homeostasis GO:0003091 15 9 0,000 0,01259077 0,03033457 ! postreplication repair GO:0006301 25 9 0,000 0,01259077 0,03030468 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01259077 0,03027485 ! icosanoid secretion GO:0032309 15 9 0,000 0,01259077 0,03024508 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01259077 0,03021537 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01259077 0,03018572 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01259077 0,03015613 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01259077 0,03012659 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01259077 0,03009711 ! sterol catabolic process GO:0016127 14 9 0,000 0,01259077 0,03006769 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01259077 0,03003833 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01259077 0,03000902 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01259077 0,02997978 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01259077 0,02995058 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01259077 0,02992145 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01259077 0,02989237 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01259077 0,02986335 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01259077 0,02983438 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01259077 0,02980547 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01259077 0,02977662 ! purine base metabolic process GO:0006144 25 9 0,000 0,01259077 0,02974782 ! pigment granule transport GO:0051904 17 9 0,000 0,01259077 0,02971908 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01259077 0,0296904 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01259077 0,02966176 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01259077 0,02963319 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01259077 0,02960467 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01259077 0,0295762 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01259077 0,02954779 ! mitochondrion localization GO:0051646 18 9 0,000 0,01259077 0,02951943 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01398012 0,03274537 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01398012 0,03271401 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01398012 0,0326827 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01398012 0,03265146 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01398012 0,03262027 ! associative learning GO:0008306 21 10 0,000 0,01398012 0,03258915 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01398012 0,03255808 ! phosphate transport GO:0006817 24 10 0,000 0,01398012 0,03252707 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01398012 0,03249612 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01398012 0,03246523 ! CTP metabolic process GO:0046036 11 10 0,000 0,01398012 0,0324344 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01398012 0,03240363 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01398012 0,03237291 ! GTP metabolic process GO:0046039 11 10 0,000 0,01398012 0,03234226 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01398012 0,03231166 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01398012 0,03228112 ! social behavior GO:0035176 29 10 0,000 0,01398012 0,03225064 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01398012 0,03222021 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01398012 0,03218984 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01398012 0,03215953 ! androgen metabolic process GO:0008209 17 10 0,000 0,01398012 0,03212928 ! phospholipid efflux GO:0033700 19 10 0,000 0,01398012 0,03209908 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01398012 0,03206894 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01398012 0,03203886 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01398012 0,03200883 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01398012 0,03197886 ! lung alveolus development GO:0048286 26 10 0,000 0,01398012 0,03194895 ! pathogenesis GO:0009405 17 10 0,000 0,01398012 0,03191909 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01398012 0,03188929 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01398012 0,03185954 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01398012 0,03182985 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01398012 0,03180021 ! endoderm development GO:0007492 18 10 0,000 0,01398012 0,03177063 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01398012 0,0317411 ! arginine catabolic process GO:0006527 17 10 0,000 0,01398012 0,03171163 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01398012 0,03168221 ! proline metabolic process GO:0006560 13 10 0,000 0,01398012 0,03165285 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01398012 0,03162354 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01398012 0,03159429 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01398012 0,03156509 ! V(D)J recombination GO:0033151 34 10 0,000 0,01398012 0,03153594 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01398012 0,03150685 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01398012 0,03147781 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01398012 0,03144883 ! B cell proliferation GO:0042100 19 10 0,000 0,01398012 0,03141989 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01398012 0,03139102 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01398012 0,03136219 ! multicellular organism growth GO:0035264 19 10 0,000 0,01398012 0,03133342 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01398012 0,0313047 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01398012 0,03127603 ! ruffle organization GO:0031529 17 10 0,000 0,01398012 0,03124742 ! epithelial cell development GO:0002064 21 10 0,000 0,01398012 0,03121885 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01398012 0,03119034 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01398012 0,03116188 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01398012 0,03113348 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01398012 0,03110512 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01398012 0,03107682 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01398012 0,03104857 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01398012 0,03102037 ! motor axon guidance GO:0008045 22 10 0,000 0,01398012 0,03099222 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01398012 0,03096412 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01398012 0,03093607 ! protein heterooligomerization GO:0051291 17 10 0,000 0,01398012 0,03090808 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01398012 0,03088013 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01398012 0,03085224 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01398012 0,03082439 ! segment specification GO:0007379 15 10 0,000 0,01398012 0,0307966 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01398012 0,03076885 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01398012 0,03074116 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01398012 0,03071351 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01398012 0,03068592 ! response to dsRNA GO:0043331 23 10 0,000 0,01398012 0,03065837 ! DNA ligation GO:0006266 18 10 0,000 0,01398012 0,03063087 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01398012 0,03060343 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01398012 0,03057603 ! melanosome localization GO:0032400 16 10 0,000 0,01398012 0,03054868 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01398012 0,03052138 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01398012 0,03049413 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01398012 0,03046693 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01398012 0,03043977 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01398012 0,03041267 ! mRNA cleavage GO:0006379 18 10 0,000 0,01398012 0,03038561 ! protein sumoylation GO:0016925 17 10 0,000 0,01398012 0,0303586 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01398012 0,03033164 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01398012 0,03030473 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01398012 0,03027786 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01398012 0,03025104 ! salivary gland development GO:0007431 28 10 0,000 0,01398012 0,03022427 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01398012 0,03019755 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01398012 0,03017087 ! midbrain development GO:0030901 14 10 0,000 0,01398012 0,03014424 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01398012 0,03011766 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01398012 0,03009112 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01398012 0,03006463 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01398012 0,03003819 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01398012 0,0300118 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01398012 0,02998545 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01398012 0,02995914 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01398012 0,02993289 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01398012 0,02990668 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01398012 0,02988051 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01398012 0,02985439 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01398012 0,02982832 ! blastocyst formation GO:0001825 18 10 0,000 0,01398012 0,02980229 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01398012 0,02977631 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01398012 0,02975037 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01398012 0,02972448 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01398012 0,02969863 ! response to nicotine GO:0035094 20 10 0,000 0,01398012 0,02967283 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01398012 0,02964707 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01398012 0,02962136 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,01536755 0,03253286 ! respiratory burst GO:0045730 17 11 0,000 0,01536755 0,03250469 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,01536755 0,03247657 ! neuron fate specification GO:0048665 18 11 0,000 0,01536755 0,03244851 ! telencephalon cell migration GO:0022029 23 11 0,000 0,01536755 0,03242048 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,01536755 0,03239251 ! thyroid gland development GO:0030878 26 11 0,000 0,01536755 0,03236459 ! synapsis GO:0007129 14 11 0,000 0,01536755 0,03233671 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,01536755 0,03230888 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,01536755 0,0322811 ! response to pain GO:0048265 27 11 0,000 0,01536755 0,03225337 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,01536755 0,03222568 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,01536755 0,03219805 ! blood vessel remodeling GO:0001974 30 11 0,000 0,01536755 0,03217045 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,01536755 0,03214291 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,01536755 0,03211542 ! bone resorption GO:0045453 16 11 0,000 0,01536755 0,03208797 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,01536755 0,03206056 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,01536755 0,03203321 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,01536755 0,0320059 ! melanocyte differentiation GO:0030318 20 11 0,000 0,01536755 0,03197864 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,01536755 0,03195142 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,01536755 0,03192425 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,01536755 0,03189713 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,01536755 0,03187005 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,01536755 0,03184302 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,01536755 0,03181603 ! UV protection GO:0009650 20 11 0,000 0,01536755 0,03178909 ! adult heart development GO:0007512 16 11 0,000 0,01536755 0,0317622 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,01536755 0,03173535 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,01536755 0,03170855 ! macroautophagy GO:0016236 19 11 0,000 0,01536755 0,03168179 ! temperature homeostasis GO:0001659 18 11 0,000 0,01536755 0,03165508 ! behavioral fear response GO:0001662 27 11 0,000 0,01536755 0,03162841 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,01536755 0,03160178 ! negative regulation of ossification GO:0030279 27 11 0,000 0,01536755 0,03157521 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,01536755 0,03154867 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,01536755 0,03152218 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,01536755 0,03149574 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,01536755 0,03146934 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,01536755 0,03144298 ! regulation of organ growth GO:0046620 14 11 0,000 0,01536755 0,03141667 ! pigment granule localization GO:0051875 20 11 0,000 0,01536755 0,0313904 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,01536755 0,03136418 ! vasoconstriction GO:0042310 20 11 0,000 0,01536755 0,031338 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,01536755 0,03131186 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,01536755 0,03128577 ! embryonic axis specification GO:0000578 19 11 0,000 0,01536755 0,03125972 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,01536755 0,03123371 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,01536755 0,03120775 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,01536755 0,03118183 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,01536755 0,03115595 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,01536755 0,03113012 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,01536755 0,03110433 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,01536755 0,03107858 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,01536755 0,03105287 ! prophase GO:0051324 17 11 0,000 0,01536755 0,03102721 ! neuroblast proliferation GO:0007405 25 11 0,000 0,01536755 0,03100159 ! nucleosome positioning GO:0016584 15 11 0,000 0,01536755 0,03097601 ! regulation of isotype switching GO:0045191 24 11 0,000 0,01536755 0,03095047 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,01536755 0,03092498 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,01536755 0,03089952 ! apical protein localization GO:0045176 18 11 0,000 0,01536755 0,03087411 ! acid secretion GO:0046717 20 11 0,000 0,01536755 0,03084874 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,01536755 0,03082342 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,01536755 0,03079813 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,01536755 0,03077289 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,01536755 0,03074768 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,01536755 0,03072252 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,01536755 0,0306974 ! cholesterol efflux GO:0033344 21 11 0,000 0,01536755 0,03067232 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,01536755 0,03064728 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,01536755 0,03062228 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,01536755 0,03059733 ! embryonic gut development GO:0048566 19 11 0,000 0,01536755 0,03057241 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,01536755 0,03054754 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,01536755 0,0305227 ! activation of innate immune response GO:0002218 16 11 0,000 0,01536755 0,0304979 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,01536755 0,03047315 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,01536755 0,03044844 ! lysogeny GO:0030069 22 11 0,000 0,01536755 0,03042376 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,01536755 0,03039913 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,01536755 0,03037453 ! sequestering of metal ion GO:0051238 15 11 0,000 0,01536755 0,03034998 ! regulation of embryonic development GO:0045995 35 11 0,000 0,01536755 0,03032546 ! nucleus localization GO:0051647 22 11 0,000 0,01536755 0,03030099 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,01675307 0,03300624 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,01675307 0,03297965 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,01675307 0,03295309 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,01675307 0,03292658 ! virus-host interaction GO:0019048 30 12 0,000 0,01675307 0,03290011 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,01675307 0,03287369 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,01675307 0,0328473 ! protein complex disassembly GO:0043241 28 12 0,000 0,01675307 0,03282096 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,01675307 0,03279466 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,01675307 0,03276841 ! hippocampus development GO:0021766 29 12 0,000 0,01675307 0,03274219 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,01675307 0,03271602 ! T cell proliferation GO:0042098 32 12 0,000 0,01675307 0,03268989 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,01675307 0,0326638 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,01675307 0,03263775 ! ventral spinal cord development GO:0021517 25 12 0,000 0,01675307 0,03261175 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,01675307 0,03258578 ! drug transport GO:0015893 16 12 0,000 0,01675307 0,03255986 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,01675307 0,03253398 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,01675307 0,03250813 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,01675307 0,03248233 ! polyamine metabolic process GO:0006595 18 12 0,000 0,01675307 0,03245658 ! focal adhesion formation GO:0048041 37 12 0,000 0,01675307 0,03243086 ! mitotic spindle organization GO:0007052 23 12 0,000 0,01675307 0,03240518 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,01675307 0,03237954 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,01675307 0,03235395 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,01675307 0,03232839 ! lipid digestion GO:0044241 21 12 0,000 0,01675307 0,03230287 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,01675307 0,0322774 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,01675307 0,03225196 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,01675307 0,03222657 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,01675307 0,03220121 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,01675307 0,0321759 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,01675307 0,03215062 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,01675307 0,03212539 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,01675307 0,03210019 ! snRNA metabolic process GO:0016073 30 12 0,000 0,01675307 0,03207503 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,01675307 0,03204992 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,01675307 0,03202484 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,01675307 0,0319998 ! cranial nerve development GO:0021545 23 12 0,000 0,01675307 0,0319748 ! fucose catabolic process GO:0019317 25 12 0,000 0,01675307 0,03194984 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,01675307 0,03192492 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,01675307 0,03190003 ! autonomic nervous system development GO:0048483 24 12 0,000 0,01675307 0,03187519 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,01675307 0,03185038 ! zymogen activation GO:0031638 18 12 0,000 0,01675307 0,03182562 ! T cell homeostasis GO:0043029 28 12 0,000 0,01675307 0,03180089 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,01675307 0,0317762 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,01675307 0,03175155 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,01675307 0,03172693 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,01675307 0,03170236 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,01675307 0,03167782 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,01675307 0,03165332 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,01675307 0,03162886 ! defense response to fungus GO:0050832 15 12 0,000 0,01675307 0,03160443 ! embryonic placenta development GO:0001892 21 12 0,000 0,01675307 0,03158005 ! lamellipodium assembly GO:0030032 24 12 0,000 0,01675307 0,0315557 ! response to cold GO:0009409 17 12 0,000 0,01675307 0,03153139 ! establishment of cell polarity GO:0030010 21 12 0,000 0,01675307 0,03150711 ! regulation of synapse organization GO:0050807 18 12 0,000 0,01675307 0,03148288 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,01813667 0,0340568 ! cGMP metabolic process GO:0046068 18 13 0,000 0,01813667 0,03403064 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,01813667 0,03400452 ! regulation of chemokine production GO:0032642 18 13 0,000 0,01813667 0,03397845 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,01813667 0,03395241 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,01813667 0,03392641 ! peroxisomal transport GO:0043574 28 13 0,000 0,01813667 0,03390046 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,01813667 0,03387454 ! cartilage condensation GO:0001502 22 13 0,000 0,01813667 0,03384866 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,01813667 0,03382282 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,01813667 0,03379702 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,01813667 0,03377126 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,01813667 0,03374554 ! endocrine pancreas development GO:0031018 25 13 0,000 0,01813667 0,03371986 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,01813667 0,03369422 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,01813667 0,03366861 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,01813667 0,03364305 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,01813667 0,03361752 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,01813667 0,03359204 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,01813667 0,03356659 ! methionine metabolic process GO:0006555 31 13 0,000 0,01813667 0,03354118 ! plasma membrane organization GO:0007009 27 13 0,000 0,01813667 0,03351581 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,01813667 0,03349047 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,01813667 0,03346518 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,01813667 0,03343992 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,01813667 0,0334147 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,01813667 0,03338952 ! cytokine metabolic process GO:0042107 24 13 0,000 0,01813667 0,03336438 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,01813667 0,03333927 ! exocrine system development GO:0035272 34 13 0,000 0,01813667 0,03331421 ! asymmetric protein localization GO:0008105 24 13 0,000 0,01813667 0,03328918 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,01813667 0,03326419 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,01813667 0,03323923 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,01813667 0,03321431 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,01813667 0,03318943 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,01813667 0,03316459 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,01813667 0,03313979 ! protein homotetramerization GO:0051289 24 13 0,000 0,01813667 0,03311502 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,01813667 0,03309029 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,01813667 0,03306559 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,01813667 0,03304094 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,01813667 0,03301632 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,01813667 0,03299173 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,01813667 0,03296718 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,01813667 0,03294267 ! histone methylation GO:0016571 29 13 0,000 0,01813667 0,0329182 ! chromatin silencing GO:0006342 29 13 0,000 0,01813667 0,03289376 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,01813667 0,03286936 ! regulation of epidermis development GO:0045682 19 13 0,000 0,01813667 0,03284499 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,01813667 0,03282066 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,01813667 0,03279637 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,01813667 0,03277211 ! spleen development GO:0048536 24 13 0,000 0,01813667 0,03274789 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,01813667 0,0327237 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,01813667 0,03269955 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,01813667 0,03267544 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,01813667 0,03265136 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,01813667 0,03262732 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,01813667 0,03260331 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,01813667 0,03257933 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,01813667 0,0325554 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,01813667 0,03253149 ! insulin secretion GO:0030073 24 13 0,000 0,01813667 0,03250763 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,01813667 0,03248379 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,01813667 0,03246 ! acrosome reaction GO:0007340 19 13 0,000 0,01813667 0,03243623 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,01813667 0,03241251 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,01813667 0,03238881 ! rRNA transcription GO:0009303 28 14 0,000 0,01951837 0,03483082 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,01951837 0,03480539 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,01951837 0,03478001 ! water transport GO:0006833 21 14 0,000 0,01951837 0,03475466 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,01951837 0,03472934 ! non-recombinational repair GO:0000726 29 14 0,000 0,01951837 0,03470407 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,01951837 0,03467883 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,01951837 0,03465362 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,01951837 0,03462846 ! RNA polyadenylation GO:0043631 32 14 0,000 0,01951837 0,03460333 ! palate development GO:0060021 32 14 0,000 0,01951837 0,03457824 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,01951837 0,03455318 ! regulated secretory pathway GO:0045055 24 14 0,000 0,01951837 0,03452816 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,01951837 0,03450317 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,01951837 0,03447823 ! arginine metabolic process GO:0006525 21 14 0,000 0,01951837 0,03445331 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,01951837 0,03442844 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,01951837 0,0344036 ! regulation of heart rate GO:0002027 25 14 0,000 0,01951837 0,03437879 ! fear response GO:0042596 34 14 0,000 0,01951837 0,03435403 ! organic alcohol transport GO:0015850 29 14 0,000 0,01951837 0,03432929 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,01951837 0,0343046 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,01951837 0,03427993 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,01951837 0,03425531 ! neutral amino acid transport GO:0015804 28 14 0,000 0,01951837 0,03423072 ! bone mineralization GO:0030282 18 14 0,000 0,01951837 0,03420616 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,01951837 0,03418164 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,01951837 0,03415715 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,01951837 0,0341327 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,01951837 0,03410829 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,01951837 0,03408391 ! regulation of cellular pH GO:0030641 27 14 0,000 0,01951837 0,03405956 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,01951837 0,03403525 ! ribosome assembly GO:0042255 18 14 0,000 0,01951837 0,03401098 ! cerebellum development GO:0021549 23 14 0,000 0,01951837 0,03398673 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,01951837 0,03396253 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,01951837 0,03393835 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,01951837 0,03391422 ! response to gamma radiation GO:0010332 30 14 0,000 0,01951837 0,03389011 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,01951837 0,03386604 ! NADP metabolic process GO:0006739 24 14 0,000 0,01951837 0,03384201 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,01951837 0,03381801 ! oxygen transport GO:0015671 22 14 0,000 0,01951837 0,03379404 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,01951837 0,0337701 ! male genitalia development GO:0030539 26 14 0,000 0,01951837 0,0337462 ! regulation of RNA stability GO:0043487 33 14 0,000 0,01951837 0,03372234 ! regulation of axon extension GO:0030516 43 14 0,000 0,01951837 0,03369851 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,01951837 0,03367471 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,01951837 0,03365094 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02089817 0,03600439 ! lactation GO:0007595 30 15 0,000 0,02089817 0,03597902 ! reproductive cellular process GO:0048610 22 15 0,000 0,02089817 0,03595368 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02089817 0,03592838 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02089817 0,03590311 ! superoxide anion generation GO:0042554 22 15 0,000 0,02089817 0,03587788 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02089817 0,03585269 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02089817 0,03582753 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02089817 0,0358024 ! copper ion transport GO:0006825 22 15 0,000 0,02089817 0,03577731 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02089817 0,03575226 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02089817 0,03572724 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02089817 0,03570225 ! sulfate transport GO:0008272 27 15 0,000 0,02089817 0,03567731 ! response to cAMP GO:0051591 25 15 0,000 0,02089817 0,03565239 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02089817 0,03562751 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02089817 0,03560267 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02089817 0,03557786 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02089817 0,03555308 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02089817 0,03552834 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02089817 0,03550363 ! vesicle coating GO:0006901 38 15 0,000 0,02089817 0,03547896 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02089817 0,03545432 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02089817 0,03542972 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02089817 0,03540515 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02089817 0,03538061 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02089817 0,03535611 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02089817 0,03533164 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02089817 0,03530721 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02089817 0,03528281 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02089817 0,03525844 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02089817 0,03523411 ! histone deacetylation GO:0016575 24 15 0,000 0,02089817 0,03520981 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02089817 0,03518554 ! water homeostasis GO:0030104 28 15 0,000 0,02089817 0,03516131 ! cofactor transport GO:0051181 30 15 0,000 0,02089817 0,03513711 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02089817 0,03511295 ! muscle maintenance GO:0046716 26 15 0,000 0,02089817 0,03508881 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02089817 0,03506471 ! intestinal absorption GO:0050892 31 15 0,000 0,02089817 0,03504065 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02089817 0,03501661 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02089817 0,03499261 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02089817 0,03496865 ! cell killing GO:0001906 32 15 0,000 0,02089817 0,03494471 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02089817 0,03492081 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02089817 0,03489694 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02089817 0,0348731 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02089817 0,0348493 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02089817 0,03482553 ! actin filament polymerization GO:0030041 27 15 0,000 0,02089817 0,03480179 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02089817 0,03477808 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,02227606 0,03704589 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,02227606 0,03702069 ! positive regulation of cell size GO:0045793 29 16 0,000 0,02227606 0,03699552 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,02227606 0,03697039 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,02227606 0,03694529 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,02227606 0,03692023 ! bone remodeling GO:0046849 28 16 0,000 0,02227606 0,03689519 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,02227606 0,0368702 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,02227606 0,03684523 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,02227606 0,03682031 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,02227606 0,03679541 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,02227606 0,03677055 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,02227606 0,03674572 ! startle response GO:0001964 28 16 0,000 0,02227606 0,03672093 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,02227606 0,03669616 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,02227606 0,03667144 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,02227606 0,03664674 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,02227606 0,03662208 ! protein polyubiquitination GO:0000209 41 16 0,000 0,02227606 0,03659745 ! glutamate metabolic process GO:0006536 25 16 0,000 0,02227606 0,03657286 ! pituitary gland development GO:0021983 30 16 0,000 0,02227606 0,0365483 ! response to osmotic stress GO:0006970 27 16 0,000 0,02227606 0,03652377 ! lysosomal transport GO:0007041 31 16 0,000 0,02227606 0,03649927 ! fructose metabolic process GO:0006000 25 16 0,000 0,02227606 0,03647481 ! L-amino acid transport GO:0015807 33 16 0,000 0,02227606 0,03645038 ! stem cell development GO:0048864 46 16 0,000 0,02227606 0,03642598 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,02227606 0,03640161 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,02227606 0,03637728 ! intermediate filament-based process GO:0045103 36 16 0,000 0,02227606 0,03635298 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,02227606 0,03632871 ! negative regulation of immune response GO:0050777 38 16 0,000 0,02227606 0,03630448 ! axon cargo transport GO:0008088 46 16 0,000 0,02227606 0,03628027 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,02227606 0,0362561 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,02227606 0,03623197 ! DNA replication initiation GO:0006270 28 16 0,000 0,02227606 0,03620786 ! neuron recognition GO:0008038 40 16 0,000 0,02227606 0,03618378 ! mRNA splice site selection GO:0006376 44 16 0,000 0,02227606 0,03615974 ! tissue regeneration GO:0042246 27 16 0,000 0,02227606 0,03613573 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,02227606 0,03611175 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,02227606 0,03608781 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,02227606 0,03606389 ! biomineral formation GO:0031214 22 16 0,000 0,02227606 0,03604001 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,02227606 0,03601616 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,02227606 0,03599234 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,02227606 0,03596855 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,02227606 0,03594479 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,02227606 0,03592106 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,02227606 0,03589737 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,02227606 0,03587371 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,02227606 0,03585007 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,02227606 0,03582647 ! peptide hormone processing GO:0016486 27 16 0,000 0,02227606 0,0358029 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,02365205 0,03798945 ! metencephalon development GO:0022037 32 17 0,000 0,02365205 0,03796449 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,02365205 0,03793956 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,02365205 0,03791467 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,02365205 0,03788981 ! signal complex assembly GO:0007172 47 17 0,000 0,02365205 0,03786498 ! filopodium assembly GO:0046847 42 17 0,000 0,02365205 0,03784018 ! endothelial cell migration GO:0043542 31 17 0,000 0,02365205 0,03781542 ! gene silencing by RNA GO:0031047 38 17 0,000 0,02365205 0,03779068 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,02365205 0,03776599 ! glial cell development GO:0021782 28 17 0,000 0,02365205 0,03774132 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,02365205 0,03771668 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,02365205 0,03769208 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,02365205 0,03766751 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,02365205 0,03764297 ! myoblast differentiation GO:0045445 50 17 0,000 0,02365205 0,03761846 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,02365205 0,03759399 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,02365205 0,03756954 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,02365205 0,03754513 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,02365205 0,03752075 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,02365205 0,0374964 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,02365205 0,03747209 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,02365205 0,0374478 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,02365205 0,03742355 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,02365205 0,03739932 ! membrane budding GO:0006900 42 17 0,000 0,02365205 0,03737513 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,02365205 0,03735097 ! regulation of protein binding GO:0043393 33 17 0,000 0,02365205 0,03732685 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,02365205 0,03730275 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,02365205 0,03727868 ! genitalia development GO:0048806 32 17 0,000 0,02365205 0,03725465 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,02365205 0,03723064 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,02365205 0,03720667 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,02365205 0,03718273 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,02365205 0,03715881 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,02365205 0,03713493 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,02365205 0,03711108 ! steroid catabolic process GO:0006706 34 17 0,000 0,02365205 0,03708726 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,02365205 0,03706347 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,02365205 0,03703972 ! gas transport GO:0015669 26 17 0,000 0,02365205 0,03701599 ! organic cation transport GO:0015695 32 17 0,000 0,02365205 0,03699229 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,02365205 0,03696862 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,02365205 0,03694499 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,02365205 0,03692138 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,02502614 0,03904142 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,02502614 0,03901651 ! limbic system development GO:0021761 40 18 0,000 0,02502614 0,03899162 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,02502614 0,03896677 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,02502614 0,03894195 ! adult walking behavior GO:0007628 36 18 0,000 0,02502614 0,03891716 ! patterning of blood vessels GO:0001569 43 18 0,000 0,02502614 0,03889241 ! heart looping GO:0001947 34 18 0,000 0,02502614 0,03886768 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,02502614 0,03884299 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,02502614 0,03881833 ! centrosome cycle GO:0007098 26 18 0,000 0,02502614 0,0387937 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,02502614 0,0387691 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,02502614 0,03874453 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,02502614 0,03871999 ! glycine metabolic process GO:0006544 30 18 0,000 0,02502614 0,03869548 ! glutamine metabolic process GO:0006541 29 18 0,000 0,02502614 0,03867101 ! response to retinoic acid GO:0032526 31 18 0,000 0,02502614 0,03864657 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,02502614 0,03862215 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,02502614 0,03859777 ! DNA integration GO:0015074 32 18 0,000 0,02502614 0,03857342 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,02502614 0,0385491 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,02502614 0,03852481 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,02502614 0,03850055 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,02502614 0,03847632 ! neural crest cell migration GO:0001755 41 18 0,000 0,02502614 0,03845212 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,02502614 0,03842795 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,02502614 0,03840381 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,02502614 0,0383797 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,02502614 0,03835562 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,02502614 0,03833158 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,02502614 0,03830756 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,02502614 0,03828357 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,02502614 0,03825962 ! detection of bacterium GO:0016045 22 18 0,000 0,02502614 0,03823569 ! nerve development GO:0021675 34 18 0,000 0,02502614 0,03821179 ! defense response to virus GO:0051607 43 18 0,000 0,02502614 0,03818792 ! microspike assembly GO:0030035 46 18 0,000 0,02502614 0,03816409 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,02502614 0,03814028 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,02502614 0,0381165 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,02639834 0,0401814 ! positive regulation of translation GO:0045727 31 19 0,000 0,02639834 0,04015638 ! negative regulation of defense response GO:0031348 27 19 0,000 0,02639834 0,04013139 ! neuron maturation GO:0042551 46 19 0,000 0,02639834 0,04010643 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,02639834 0,04008151 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,02639834 0,04005661 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,02639834 0,04003175 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,02639834 0,04000691 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,02639834 0,03998211 ! inositol metabolic process GO:0006020 33 19 0,000 0,02639834 0,03995734 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,02639834 0,0399326 ! memory GO:0007613 34 19 0,000 0,02639834 0,03990789 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,02639834 0,03988321 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,02639834 0,03985856 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,02639834 0,03983394 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,02639834 0,03980935 ! cerebral cortex development GO:0021987 40 19 0,000 0,02639834 0,03978479 ! pigmentation during development GO:0048066 42 19 0,000 0,02639834 0,03976026 ! response to vitamin A GO:0033189 32 19 0,000 0,02639834 0,03973576 ! heme metabolic process GO:0042168 40 19 0,000 0,02639834 0,0397113 ! neuromuscular junction development GO:0007528 43 19 0,000 0,02639834 0,03968686 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,02639834 0,03966245 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,02639834 0,03963807 ! response to fungus GO:0009620 26 19 0,000 0,02639834 0,03961373 ! peptide cross-linking GO:0018149 39 19 0,000 0,02639834 0,03958941 ! protein export from nucleus GO:0006611 40 19 0,000 0,02639834 0,03956512 ! heart process GO:0003015 32 19 0,000 0,02639834 0,03954086 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,02639834 0,03951663 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,02639834 0,03949243 ! visual learning GO:0008542 38 19 0,000 0,02639834 0,03946826 ! cellular pigmentation GO:0033059 37 19 0,000 0,02639834 0,03944413 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,02639834 0,03942002 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,02639834 0,03939593 ! vitamin transport GO:0051180 31 19 0,000 0,02639834 0,03937188 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,02639834 0,03934786 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,02639834 0,03932387 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,02639834 0,03929991 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,02639834 0,03927597 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,02639834 0,03925207 ! cilium assembly GO:0042384 38 19 0,000 0,02639834 0,03922819 ! peptide hormone secretion GO:0030072 32 19 0,000 0,02639834 0,03920434 ! protein secretion GO:0009306 45 20 0,000 0,02776865 0,04121434 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,02776865 0,04118931 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,02776865 0,04116432 ! positive regulation of ossification GO:0045778 50 20 0,000 0,02776865 0,04113936 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,02776865 0,04111442 ! skin development GO:0043588 42 20 0,000 0,02776865 0,04108952 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,02776865 0,04106465 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,02776865 0,04103981 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,02776865 0,04101499 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,02776865 0,04099021 ! response to vitamin GO:0033273 36 20 0,000 0,02776865 0,04096546 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,02776865 0,04094074 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,02776865 0,04091604 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,02776865 0,04089138 ! bile acid metabolic process GO:0008206 34 20 0,000 0,02776865 0,04086675 ! response to alkaloid GO:0043279 38 20 0,000 0,02776865 0,04084214 ! retinoid metabolic process GO:0001523 34 20 0,000 0,02776865 0,04081757 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,02776865 0,04079302 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,02776865 0,04076851 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,02776865 0,04074402 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,02776865 0,04071957 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,02776865 0,04069514 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,02776865 0,04067074 ! body fluid secretion GO:0007589 33 20 0,000 0,02776865 0,04064637 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,02776865 0,04062204 ! peptide secretion GO:0002790 38 20 0,000 0,02776865 0,04059773 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,02776865 0,04057344 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,02776865 0,04054919 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,02776865 0,04052497 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,02776865 0,04050078 ! cell-cell junction organization GO:0045216 43 20 0,000 0,02776865 0,04047661 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,02776865 0,04045247 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,02776865 0,04042837 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,02776865 0,04040429 ! regulation of glucose import GO:0046324 30 20 0,000 0,02776865 0,04038024 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,02776865 0,04035622 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,02776865 0,04033222 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,02776865 0,04030826 ! negative regulation of translation GO:0017148 32 20 0,000 0,02776865 0,04028432 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,02776865 0,04026042 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,02913706 0,04221936 ! hormone secretion GO:0046879 39 21 0,000 0,02913706 0,04219433 ! lipid phosphorylation GO:0046834 43 21 0,000 0,02913706 0,04216933 ! cAMP metabolic process GO:0046058 41 21 0,000 0,02913706 0,04214437 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,02913706 0,04211943 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,02913706 0,04209452 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,02913706 0,04206964 ! ovarian follicle development GO:0001541 39 21 0,000 0,02913706 0,04204479 ! smooth muscle contraction GO:0006939 48 21 0,000 0,02913706 0,04201997 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,02913706 0,04199518 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,02913706 0,04197042 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,02913706 0,04194569 ! plasma membrane fusion GO:0045026 33 21 0,000 0,02913706 0,04192099 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,02913706 0,04189631 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,02913706 0,04187167 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,02913706 0,04184705 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,02913706 0,04182247 ! diencephalon development GO:0021536 36 21 0,000 0,02913706 0,04179791 ! collagen fibril organization GO:0030199 62 21 0,000 0,02913706 0,04177338 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,02913706 0,04174888 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,02913706 0,04172441 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,02913706 0,04169996 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,02913706 0,04167555 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,02913706 0,04165116 ! collagen catabolic process GO:0030574 29 21 0,000 0,02913706 0,04162681 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,02913706 0,04160248 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,02913706 0,04157818 ! sperm-egg recognition GO:0035036 23 21 0,000 0,02913706 0,0415539 ! actin filament-based movement GO:0030048 47 21 0,000 0,02913706 0,04152966 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,02913706 0,04150544 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,03050359 0,04342673 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,03050359 0,04340143 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,03050359 0,04337617 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,03050359 0,04335094 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,03050359 0,04332573 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,03050359 0,04330056 ! microtubule-based transport GO:0010970 59 22 0,000 0,03050359 0,04327541 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,03050359 0,0432503 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,03050359 0,04322521 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,03050359 0,04320015 ! cellular response to starvation GO:0009267 37 22 0,000 0,03050359 0,04317512 ! vacuolar transport GO:0007034 41 22 0,000 0,03050359 0,04315012 ! central nervous system neuron development GO:0021954 47 22 0,000 0,03050359 0,04312515 ! fucose metabolic process GO:0006004 44 22 0,000 0,03050359 0,04310021 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,03050359 0,0430753 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,03050359 0,04305041 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,03050359 0,04302556 ! ureteric bud development GO:0001657 50 22 0,000 0,03050359 0,04300073 ! cell aging GO:0007569 48 22 0,000 0,03050359 0,04297593 ! stem cell differentiation GO:0048863 57 22 0,000 0,03050359 0,04295116 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,03050359 0,04292642 ! cytolysis GO:0019835 27 22 0,000 0,03050359 0,04290171 ! renal system process GO:0003014 42 22 0,000 0,03050359 0,04287702 ! vasodilation GO:0042311 40 22 0,000 0,03050359 0,04285237 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,03050359 0,04282774 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,03050359 0,04280314 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,03050359 0,04277857 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,03050359 0,04275402 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,03050359 0,04272951 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,03050359 0,04270502 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,03050359 0,04268056 ! sarcomere organization GO:0045214 32 22 0,000 0,03050359 0,04265613 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,03050359 0,04263173 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,03050359 0,04260735 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,03050359 0,04258301 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,03050359 0,04255869 ! gut development GO:0048565 44 22 0,000 0,03050359 0,0425344 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,03050359 0,04251013 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,03050359 0,0424859 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,03050359 0,04246169 ! protein stabilization GO:0050821 41 22 0,000 0,03050359 0,04243751 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,03186823 0,0443108 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,03186823 0,0442856 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,03186823 0,04426042 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,03186823 0,04423528 ! gluconeogenesis GO:0006094 38 23 0,000 0,03186823 0,04421016 ! glycerol metabolic process GO:0006071 40 23 0,000 0,03186823 0,04418506 ! viral genome replication GO:0019079 44 23 0,000 0,03186823 0,04416 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,03186823 0,04413497 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,03186823 0,04410996 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,03186823 0,04408499 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,03186823 0,04406004 ! regeneration GO:0031099 42 23 0,000 0,03186823 0,04403512 ! axis specification GO:0009798 43 23 0,000 0,03186823 0,04401022 ! visual behavior GO:0007632 46 23 0,000 0,03186823 0,04398536 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,03186823 0,04396052 ! response to ethanol GO:0045471 47 23 0,000 0,03186823 0,04393571 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,03186823 0,04391093 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,03186823 0,04388618 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,03186823 0,04386146 ! peroxisome organization GO:0007031 43 23 0,000 0,03186823 0,04383676 ! lysosome organization GO:0007040 47 23 0,000 0,03186823 0,04381209 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,03186823 0,04378745 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,03186823 0,04376284 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,03186823 0,04373825 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,03186823 0,04371369 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,03186823 0,04368916 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,03186823 0,04366466 ! DNA modification GO:0006304 36 23 0,000 0,03186823 0,04364018 ! fatty acid transport GO:0015908 47 23 0,000 0,03186823 0,04361573 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,03186823 0,04359131 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,03186823 0,04356692 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,03186823 0,04354255 ! hormone transport GO:0009914 41 23 0,000 0,03186823 0,04351821 ! cell-cell recognition GO:0009988 28 23 0,000 0,03186823 0,0434939 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,03186823 0,04346962 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,03186823 0,04344536 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,03186823 0,04342113 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,03323099 0,04525268 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,03323099 0,04522747 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,03323099 0,04520229 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,03323099 0,04517713 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,03323099 0,04515201 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,03323099 0,04512691 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,03323099 0,04510184 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,03323099 0,04507679 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,03323099 0,04505178 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,03323099 0,04502679 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,03323099 0,04500183 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,03323099 0,0449769 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,03323099 0,044952 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,03323099 0,04492712 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,03323099 0,04490227 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,03323099 0,04487745 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,03323099 0,04485266 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,03323099 0,04482789 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,03323099 0,04480315 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,03323099 0,04477844 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,03323099 0,04475375 ! pallium development GO:0021543 56 24 0,000 0,03323099 0,04472909 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,03323099 0,04470446 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,03323099 0,04467986 ! platelet activation GO:0030168 41 24 0,000 0,03323099 0,04465528 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,03323099 0,04463073 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,03323099 0,04460621 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,03323099 0,04458172 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,03323099 0,04455725 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,03323099 0,04453281 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,03323099 0,04450839 ! regulation of amine transport GO:0051952 41 24 0,000 0,03323099 0,044484 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,03459187 0,04628036 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,03459187 0,04625503 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,03459187 0,04622972 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,03459187 0,04620445 ! phototransduction GO:0007602 37 25 0,000 0,03459187 0,0461792 ! keratinization GO:0031424 37 25 0,000 0,03459187 0,04615398 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,03459187 0,04612879 ! vacuole organization GO:0007033 49 25 0,000 0,03459187 0,04610362 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,03459187 0,04607848 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,03459187 0,04605337 ! receptor metabolic process GO:0043112 53 25 0,000 0,03459187 0,04602829 ! chromosome condensation GO:0030261 48 25 0,000 0,03459187 0,04600323 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,03459187 0,0459782 ! regulation of behavior GO:0050795 48 25 0,000 0,03459187 0,0459532 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,03459187 0,04592823 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,03459187 0,04590328 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,03459187 0,04587836 ! immunoglobulin production GO:0002377 62 25 0,000 0,03459187 0,04585346 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,03459187 0,0458286 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,03459187 0,04580376 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,03459187 0,04577895 ! liver development GO:0001889 55 25 0,000 0,03459187 0,04575416 ! protein tetramerization GO:0051262 57 25 0,000 0,03459187 0,0457294 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,03595087 0,04750026 ! myelination GO:0042552 50 26 0,000 0,03595087 0,04747458 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,03595087 0,04744893 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,03595087 0,04742331 ! molting cycle process GO:0022404 52 26 0,000 0,03595087 0,04739772 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,03595087 0,04737216 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,03595087 0,04734662 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,03595087 0,04732111 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,03595087 0,04729563 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,03595087 0,04727017 ! digestive system process GO:0022600 49 26 0,000 0,03595087 0,04724474 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,03595087 0,04721934 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,03595087 0,04719397 ! osteoblast differentiation GO:0001649 63 26 0,000 0,03595087 0,04716862 ! neural crest cell development GO:0014032 59 26 0,000 0,03595087 0,04714331 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,03595087 0,04711801 ! negative regulation of cell development GO:0010721 83 26 0,000 0,03595087 0,04709275 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,03595087 0,04706751 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,03595087 0,0470423 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,03595087 0,04701712 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,03595087 0,04699196 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,03595087 0,04696683 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,03595087 0,04694173 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,03595087 0,04691666 ! blastocyst development GO:0001824 50 26 0,000 0,03595087 0,04689161 ! telomere organization GO:0032200 46 26 0,000 0,03595087 0,04686658 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,03595087 0,04684159 ! neural tube closure GO:0001843 58 26 0,000 0,03595087 0,04681662 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,03595087 0,04679168 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,03595087 0,04676676 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,03595087 0,04674187 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,037308 0,04848055 ! embryonic pattern specification GO:0009880 49 27 0,000 0,037308 0,04845478 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,037308 0,04842903 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,037308 0,04840331 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,037308 0,04837762 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,037308 0,04835196 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,037308 0,04832632 ! iron ion transport GO:0006826 65 27 0,000 0,037308 0,04830071 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,037308 0,04827513 ! superoxide metabolic process GO:0006801 41 27 0,000 0,037308 0,04824957 ! tube lumen formation GO:0035148 59 27 0,000 0,037308 0,04822404 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,037308 0,04819854 ! insulin receptor signaling pathway GO:0008286 66 27 0,000 0,037308 0,04817307 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,037308 0,04814762 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,037308 0,0481222 ! response to starvation GO:0042594 47 27 0,000 0,037308 0,0480968 ! response to toxin GO:0009636 49 27 0,000 0,037308 0,04807144 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,037308 0,04804609 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,037308 0,04802078 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,037308 0,04799549 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,037308 0,04797023 ! leukocyte proliferation GO:0070661 59 27 0,000 0,037308 0,047945 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,037308 0,04791979 ! neuron fate commitment GO:0048663 52 28 0,000 0,03866325 0,04963443 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,03866325 0,04960837 ! circadian rhythm GO:0007623 56 28 0,000 0,03866325 0,04958233 ! dendrite development GO:0016358 67 28 0,000 0,03866325 0,04955631 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,03866325 0,04953032 ! fat cell differentiation GO:0045444 57 28 0,000 0,03866325 0,04950437 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,03866325 0,04947843 ! sperm motility GO:0030317 37 28 0,000 0,03866325 0,04945253 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,03866325 0,04942665 ! base-excision repair GO:0006284 41 28 0,000 0,03866325 0,0494008 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,03866325 0,04937498 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,03866325 0,04934918 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,03866325 0,04932341 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,03866325 0,04929767 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,03866325 0,04927195 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,03866325 0,04924626 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,03866325 0,0492206 ! glutathione metabolic process GO:0006749 42 28 0,000 0,03866325 0,04919496 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,03866325 0,04916935 ! lipid oxidation GO:0034440 48 28 0,000 0,03866325 0,04914377 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,03866325 0,04911822 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,03866325 0,04909269 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,04001664 0,05078475 ! translational initiation GO:0006413 66 29 0,000 0,04001664 0,05075839 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,04001664 0,05073204 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,04001664 0,05070573 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,04001664 0,05067945 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,04001664 0,05065319 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,04001664 0,05062696 ! primary neural tube formation GO:0014020 61 29 0,000 0,04001664 0,05060075 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,04001664 0,05057457 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,04001664 0,05054842 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,04001664 0,0505223 ! somitogenesis GO:0001756 52 29 0,000 0,04001664 0,0504962 ! synaptogenesis GO:0007416 46 29 0,000 0,04001664 0,05047013 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,04001664 0,05044409 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,04001664 0,05041808 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,04001664 0,05039209 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,04001664 0,05036613 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,04136816 0,05204038 ! phenol metabolic process GO:0018958 56 30 0,000 0,04136816 0,05201359 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,04136816 0,05198684 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,04136816 0,05196011 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,04136816 0,05193341 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,04136816 0,05190673 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,04136816 0,05188009 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,04136816 0,05185347 ! acute-phase response GO:0006953 50 30 0,000 0,04136816 0,05182688 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,04136816 0,05180031 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,04136816 0,05177378 ! myofibril assembly GO:0030239 50 30 0,000 0,04136816 0,05174727 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,04136816 0,05172078 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,04136816 0,05169433 ! cell fate determination GO:0001709 64 30 0,000 0,04136816 0,0516679 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,04136816 0,0516415 ! phospholipid transport GO:0015914 65 30 0,000 0,04136816 0,05161512 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,04136816 0,05158877 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,04136816 0,05156245 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,04136816 0,05153616 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,04136816 0,05150989 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,04136816 0,05148365 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,04271781 0,05313626 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,04271781 0,05310922 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,04271781 0,0530822 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,04271781 0,05305522 ! cell junction assembly GO:0034329 85 31 0,000 0,04271781 0,05302826 ! regulation of innate immune response GO:0045088 57 31 0,000 0,04271781 0,05300133 ! ovulation cycle process GO:0022602 55 31 0,000 0,04271781 0,05297442 ! peptide transport GO:0015833 60 31 0,000 0,04271781 0,05294755 ! male gonad development GO:0008584 56 31 0,000 0,04271781 0,0529207 ! iron ion homeostasis GO:0055072 60 31 0,000 0,04271781 0,05289387 ! detection of light stimulus GO:0009583 44 31 0,000 0,04271781 0,05286708 ! natural killer cell activation GO:0030101 50 31 0,000 0,04271781 0,05284031 ! ensheathment of neurons GO:0007272 64 31 0,000 0,04271781 0,05281357 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,04271781 0,05278686 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,04271781 0,05276017 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,04271781 0,05273351 ! eye morphogenesis GO:0048592 65 31 0,000 0,04271781 0,05270687 ! response to heat GO:0009408 54 31 0,000 0,04271781 0,05268027 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,04271781 0,05265369 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,0440656 0,05428758 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,0440656 0,05426021 ! collagen metabolic process GO:0032963 49 32 0,000 0,0440656 0,05423288 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,0440656 0,05420557 ! spindle organization GO:0007051 50 32 0,000 0,0440656 0,05417829 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,0440656 0,05415104 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,0440656 0,05412381 ! metanephros development GO:0001656 81 32 0,000 0,0440656 0,05409662 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,0440656 0,05406945 ! muscle cell development GO:0055001 52 32 0,000 0,0440656 0,0540423 ! mesoderm formation GO:0001707 73 32 0,000 0,0440656 0,05401519 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,0440656 0,0539881 ! ovulation cycle GO:0042698 57 32 0,000 0,0440656 0,05396104 ! peripheral nervous system development GO:0007422 68 32 0,000 0,0440656 0,053934 ! BMP signaling pathway GO:0030509 71 32 0,000 0,0440656 0,05390699 ! hindbrain development GO:0030902 65 32 0,000 0,0440656 0,05388001 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,0440656 0,05385306 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,0440656 0,05382613 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,0440656 0,05379923 ! gene silencing GO:0016458 71 32 0,000 0,0440656 0,05377236 ! regulation of pH GO:0006885 56 33 0,000 0,04541153 0,05538711 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,04541153 0,05535947 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,04541153 0,05533186 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,04541153 0,05530428 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,04541153 0,05527672 ! response to ionizing radiation GO:0010212 74 33 0,000 0,04541153 0,05524919 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,04541153 0,05522169 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,04541153 0,05519422 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,04541153 0,05516677 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,04541153 0,05513935 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,04541153 0,05511196 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,04541153 0,0550846 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,04675561 0,05668682 ! glial cell differentiation GO:0010001 67 34 0,000 0,04675561 0,05665871 ! post-embryonic development GO:0009791 76 34 0,000 0,04675561 0,05663062 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,04675561 0,05660255 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,04675561 0,05657452 ! spliceosome assembly GO:0000245 75 34 0,000 0,04675561 0,05654651 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,04675561 0,05651853 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,04675561 0,05649058 ! formation of primary germ layer GO:0001704 76 34 0,000 0,04675561 0,05646265 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,04675561 0,05643476 ! adult locomotory behavior GO:0008344 62 34 0,000 0,04675561 0,05640689 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,04809783 0,05799753 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,04809783 0,05796892 ! negative regulation of secretion GO:0051048 68 35 0,000 0,04809783 0,05794033 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,04809783 0,05791178 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,04809783 0,05788325 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,04809783 0,05785475 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,04809783 0,05782628 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,04809783 0,05779783 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,04809783 0,05776942 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,04809783 0,05774103 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,04809783 0,05771267 ! ceramide metabolic process GO:0006672 72 35 0,000 0,04809783 0,05768434 ! telencephalon development GO:0021537 81 35 0,000 0,04809783 0,05765603 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,04809783 0,05762776 ! placenta development GO:0001890 53 35 0,000 0,04809783 0,05759951 ! regulation of muscle development GO:0048634 82 36 0,000 0,0494382 0,05917565 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,0494382 0,05914668 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,0494382 0,05911772 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,0494382 0,0590888 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,0494382 0,05905991 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,0494382 0,05903104 ! positive regulation of cell development GO:0010720 85 36 0,000 0,0494382 0,0590022 ! protein targeting to membrane GO:0006612 75 36 0,000 0,0494382 0,05897339 ! regulation of proteolysis GO:0030162 77 36 0,000 0,0494382 0,05894461 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,0494382 0,05891586 ! aerobic respiration GO:0009060 56 36 0,000 0,0494382 0,05888713 ! cytokine production GO:0001816 68 36 0,000 0,0494382 0,05885844 ! embryonic organ development GO:0048568 67 36 0,000 0,0494382 0,05882977 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,0494382 0,05880113 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,0494382 0,05877251 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,05077671 0,06033439 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,05077671 0,06030506 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,05077671 0,06027576 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,05077671 0,06024648 ! sister chromatid segregation GO:0000819 65 37 0,000 0,05077671 0,06021724 ! odontogenesis GO:0042476 74 37 0,000 0,05077671 0,06018802 ! actomyosin structure organization GO:0031032 68 37 0,000 0,05077671 0,06015883 ! cell junction organization GO:0034330 96 37 0,000 0,05077671 0,06012967 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,05077671 0,06010054 ! female gonad development GO:0008585 71 37 0,000 0,05077671 0,06007143 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,05077671 0,06004236 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,05077671 0,06001331 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,05211338 0,06156334 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,05211338 0,06153359 ! meiosis I GO:0007127 74 38 0,000 0,05211338 0,06150386 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,05211338 0,06147417 ! organic anion transport GO:0015711 82 38 0,000 0,05211338 0,0614445 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,05211338 0,06141486 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,05211338 0,06138524 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,05211338 0,06135566 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,05211338 0,06132611 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,05211338 0,06129658 ! regulation of protein stability GO:0031647 77 38 0,000 0,05211338 0,06126708 ! spermatid development GO:0007286 69 38 0,000 0,05211338 0,06123761 ! pigment metabolic process GO:0042440 87 38 0,000 0,05211338 0,06120817 ! cellular response to insulin stimulus GO:0032869 85 38 0,000 0,05211338 0,06117876 ! neural tube formation GO:0001841 79 38 0,000 0,05211338 0,06114937 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,05344821 0,06268554 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,05344821 0,06265546 ! negative regulation of binding GO:0051100 71 39 0,000 0,05344821 0,06262541 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,05344821 0,06259539 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,05344821 0,06256539 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,05344821 0,06253543 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,05344821 0,06250549 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,05344821 0,06247559 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,05344821 0,06244571 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,05478119 0,06397249 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,05478119 0,06394193 ! learning GO:0007612 82 40 0,000 0,05478119 0,06391139 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,05478119 0,06388089 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,05478119 0,06385041 ! mismatch repair GO:0006298 58 40 0,000 0,05478119 0,06381996 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,05478119 0,06378954 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,05478119 0,06375915 ! RNA export from nucleus GO:0006405 61 41 0,000 0,05611234 0,06527735 ! mRNA catabolic process GO:0006402 79 41 0,000 0,05611234 0,06524628 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,05611234 0,06521524 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,05611234 0,06518423 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,05611234 0,06515325 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,05611234 0,0651223 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,05611234 0,06509138 ! feeding behavior GO:0007631 69 41 0,000 0,05611234 0,06506048 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,05611234 0,06502962 ! mesenchymal cell development GO:0014031 94 41 0,000 0,05611234 0,06499879 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,05611234 0,06496798 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,05611234 0,06493721 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,05611234 0,06490646 ! spermatid differentiation GO:0048515 73 41 0,000 0,05611234 0,06487574 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,05611234 0,06484505 ! RNA modification GO:0009451 64 41 0,000 0,05611234 0,06481439 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,05744164 0,0663185 ! ear morphogenesis GO:0042471 64 42 0,000 0,05744164 0,06628717 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,05744164 0,06625587 ! T cell differentiation GO:0030217 93 42 0,000 0,05744164 0,0662246 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,05744164 0,06619337 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,05744164 0,06616216 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,05744164 0,06613098 ! regulation of protein secretion GO:0050708 77 42 0,000 0,05744164 0,06609983 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,05744164 0,06606871 ! cytokinesis GO:0000910 84 42 0,000 0,05744164 0,06603762 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,05744164 0,06600656 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,05876912 0,06750021 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,05876912 0,06746849 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,05876912 0,0674368 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,05876912 0,06740514 ! regulation of tube size GO:0035150 76 43 0,000 0,05876912 0,06737351 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,05876912 0,06734191 ! glucose transport GO:0015758 66 43 0,000 0,05876912 0,06731034 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,05876912 0,0672788 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,05876912 0,06724728 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,05876912 0,0672158 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,05876912 0,06718435 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,05876912 0,06715292 ! segmentation GO:0035282 78 43 0,000 0,05876912 0,06712153 ! ion transmembrane transport GO:0034220 79 43 0,000 0,05876912 0,06709016 ! neuron migration GO:0001764 85 43 0,000 0,05876912 0,06705883 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,06009476 0,06853944 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,06009476 0,06850746 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,06009476 0,06847551 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,06009476 0,06844359 ! hexose transport GO:0008645 68 44 0,000 0,06009476 0,06841169 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,06009476 0,06837983 ! striated muscle contraction GO:0006941 85 44 0,000 0,06009476 0,06834799 ! phagocytosis GO:0006909 105 44 0,000 0,06009476 0,06831619 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,06009476 0,06828441 ! double-strand break repair GO:0006302 85 44 0,000 0,06009476 0,06825267 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,06141857 0,06972377 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,06141857 0,06969139 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,06141857 0,06965903 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,06141857 0,06962671 ! biopolymer methylation GO:0043414 91 45 0,000 0,06141857 0,06959441 ! B cell differentiation GO:0030183 124 45 0,000 0,06141857 0,06956215 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,06141857 0,06952992 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,06141857 0,06949771 ! polyol metabolic process GO:0019751 77 45 0,000 0,06141857 0,06946554 ! developmental growth GO:0048589 88 45 0,000 0,06141857 0,06943339 ! maintenance of location in cell GO:0051651 101 45 0,000 0,06141857 0,06940128 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,06274055 0,0708623 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,06274055 0,07082956 ! glycolysis GO:0006096 71 46 0,000 0,06274055 0,07079684 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,06274055 0,07076416 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,06274055 0,0707315 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,06274055 0,07069888 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,06274055 0,07066628 ! pigmentation GO:0043473 103 46 0,000 0,06274055 0,07063372 ! neural tube development GO:0021915 91 47 0,000 0,06406071 0,07208674 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,06406071 0,07205355 ! response to insulin stimulus GO:0032868 98 47 0,000 0,06406071 0,07202039 ! positive regulation of defense response GO:0031349 88 48 0,000 0,06537904 0,07346872 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,06537904 0,07343494 ! mitochondrial transport GO:0006839 94 48 0,000 0,06537904 0,0734012 ! cellular component disassembly GO:0022411 89 48 0,000 0,06537904 0,07336748 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,06537904 0,07333379 ! endosome transport GO:0016197 127 48 0,000 0,06537904 0,07330014 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,06537904 0,07326652 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,06537904 0,07323292 ! male sex differentiation GO:0046661 93 48 0,000 0,06537904 0,07319936 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,06537904 0,07316583 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,06537904 0,07313233 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,06537904 0,07309886 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,06537904 0,07306542 ! methylation GO:0032259 97 48 0,000 0,06537904 0,07303201 ! response to calcium ion GO:0051592 94 49 0,000 0,06669556 0,07446858 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,06669556 0,07443456 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,06669556 0,07440057 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,06669556 0,07436661 ! JNK cascade GO:0007254 106 49 0,000 0,06669556 0,07433269 ! regulation of action potential GO:0001508 102 50 0,000 0,06801026 0,07576337 ! regulation of ion transport GO:0043269 86 50 0,000 0,06801026 0,07572883 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,06801026 0,07569433 ! endocrine system development GO:0035270 109 50 0,000 0,06801026 0,07565986 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,06801026 0,07562543 ! activation of caspase activity GO:0006919 95 50 0,000 0,06801026 0,07559102 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,06801026 0,07555664 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,06801026 0,0755223 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,06801026 0,07548799 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,06801026 0,07545371 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,06801026 0,07541946 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,06932314 0,07684049 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,06932314 0,07680564 ! peptide metabolic process GO:0006518 80 51 0,000 0,06932314 0,07677082 ! response to temperature stimulus GO:0009266 84 51 0,000 0,06932314 0,07673604 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,06932314 0,07670128 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,06932314 0,07666656 ! positive regulation of binding GO:0051099 88 52 0,000 0,07063421 0,07808117 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,07063421 0,07804585 ! Notch signaling pathway GO:0007219 111 52 0,000 0,07063421 0,07801057 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,07063421 0,07797532 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,07063421 0,0779401 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,07063421 0,07790491 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,07063421 0,07786976 ! excretion GO:0007588 87 52 0,000 0,07063421 0,07783463 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,07063421 0,07779954 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,07063421 0,07776448 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,07063421 0,07772945 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,07063421 0,07769445 ! amino acid activation GO:0043038 98 52 0,000 0,07063421 0,07765949 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,07194347 0,07906339 ! positive regulation of growth GO:0045927 96 53 0,000 0,07194347 0,07902784 ! inner ear development GO:0048839 89 53 0,000 0,07194347 0,07899232 ! chromatin remodeling GO:0006338 122 53 0,000 0,07194347 0,07895683 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,07194347 0,07892138 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,07194347 0,07888595 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,07194347 0,07885056 ! cartilage development GO:0051216 99 53 0,000 0,07194347 0,0788152 ! synapse organization GO:0050808 102 53 0,000 0,07194347 0,07877988 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,07325093 0,08017563 ! regulation of translational initiation GO:0006446 87 54 0,000 0,07325093 0,08013973 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,07325093 0,08010386 ! neuromuscular process GO:0050905 107 54 0,000 0,07325093 0,08006802 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,07325093 0,08003221 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,07325093 0,07999643 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,07325093 0,07996069 ! regulation of cell shape GO:0008360 142 54 0,000 0,07325093 0,07992497 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,07325093 0,07988929 ! RNA catabolic process GO:0006401 103 55 0,000 0,07455657 0,08127698 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,07455657 0,08124073 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,07455657 0,08120451 ! cell recognition GO:0008037 98 55 0,000 0,07455657 0,08116832 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,07455657 0,08113217 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,07455657 0,08109604 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,07586042 0,08247753 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,07586042 0,08244084 ! glucose catabolic process GO:0006007 88 56 0,000 0,07586042 0,08240418 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,07586042 0,08236756 ! regulation of DNA replication GO:0006275 105 56 0,000 0,07586042 0,08233097 ! RNA elongation GO:0006354 90 56 0,000 0,07586042 0,08229441 ! chloride transport GO:0006821 102 57 0,000 0,07716247 0,08366973 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,07716247 0,08363261 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,07716247 0,08359552 ! heart morphogenesis GO:0003007 105 57 0,000 0,07716247 0,08355847 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,07716247 0,08352145 ! regulation of actin filament length GO:0030832 118 58 0,000 0,07846271 0,08489123 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,07846271 0,08485366 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,07846271 0,08481611 ! aging GO:0007568 112 58 0,000 0,07846271 0,0847786 ! gastrulation GO:0007369 122 58 0,000 0,07846271 0,08474112 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,07846271 0,08470367 ! maintenance of location GO:0051235 124 58 0,000 0,07846271 0,08466626 ! nuclear export GO:0051168 110 59 0,000 0,07976116 0,08602937 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,08105782 0,08738935 ! lipid modification GO:0030258 112 60 0,000 0,08105782 0,0873508 ! DNA catabolic process GO:0006308 94 60 0,000 0,08105782 0,08731229 ! regulation of endocytosis GO:0030100 104 60 0,000 0,08105782 0,0872738 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,08105782 0,08723536 ! adult behavior GO:0030534 104 60 0,000 0,08105782 0,08719695 ! kidney development GO:0001822 133 60 0,000 0,08105782 0,08715857 ! positive regulation of secretion GO:0051047 110 61 0,000 0,08235269 0,08851193 ! regulation of cellular component size GO:0032535 125 61 0,000 0,08235269 0,08847301 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,08235269 0,08843412 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,08235269 0,08839527 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,08235269 0,08835645 ! regulation of heart contraction GO:0008016 123 61 0,000 0,08235269 0,08831766 ! camera-type eye development GO:0043010 126 61 0,000 0,08235269 0,08827891 ! proton transport GO:0015992 117 61 0,000 0,08235269 0,08824019 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,08235269 0,0882015 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,08364577 0,08954716 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,08364577 0,08950794 ! tRNA processing GO:0008033 102 62 0,000 0,08364577 0,08946875 ! regulation of mitosis GO:0007088 112 63 0,000 0,08493707 0,09081018 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,08493707 0,09077045 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,08493707 0,09073076 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,08493707 0,09069111 ! hydrogen transport GO:0006818 121 64 0,000 0,08622658 0,09202775 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,08622658 0,09198757 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,08622658 0,09194742 ! response to peptide hormone stimulus GO:0043434 129 64 0,000 0,08622658 0,0919073 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,08751431 0,09323919 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,08751431 0,09319854 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,08751431 0,09315793 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,08751431 0,09311736 ! ear development GO:0043583 114 66 0,000 0,08880026 0,09444451 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,08880026 0,09440341 ! gonad development GO:0008406 115 66 0,000 0,08880026 0,09436235 ! activation of MAPK activity GO:0000187 124 67 0,000 0,09008444 0,09568534 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,09008444 0,09564375 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,09008444 0,09560221 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,09008444 0,09556069 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,09008444 0,09551922 ! secondary metabolic process GO:0019748 125 67 0,000 0,09008444 0,09547778 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,09136684 0,09679496 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,09136684 0,09675301 ! hexose catabolic process GO:0019320 113 68 0,000 0,09136684 0,09671109 ! extracellular matrix organization GO:0030198 146 68 0,000 0,09136684 0,0966692 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,09136684 0,09662735 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,09136684 0,09658554 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,09136684 0,09654377 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,09136684 0,09650203 ! cell projection assembly GO:0030031 138 68 0,000 0,09136684 0,09646032 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,09264747 0,09777009 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,09264747 0,09772788 ! urogenital system development GO:0001655 149 69 0,000 0,09264747 0,0976857 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,09264747 0,09764356 ! single fertilization GO:0007338 83 69 0,000 0,09264747 0,09760145 ! cell redox homeostasis GO:0045454 114 70 0,000 0,09392633 0,09890605 ! activation of immune response GO:0002253 120 70 0,000 0,09392633 0,09886343 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,09392633 0,09882086 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,09520343 0,10012138 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,09520343 0,1000783 ! appendage morphogenesis GO:0035107 150 72 0,000 0,09647876 0,10137531 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,09647876 0,10133173 ! actin filament organization GO:0007015 167 72 0,000 0,09647876 0,10128818 ! B cell activation GO:0042113 179 72 0,000 0,09647876 0,10124468 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,09647876 0,1012012 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,09647876 0,10115777 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,09647876 0,10111437 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,09647876 0,10107101 ! appendage development GO:0048736 151 73 0,000 0,09775233 0,10236131 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,09775233 0,10231745 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,09775233 0,10227363 ! acute inflammatory response GO:0002526 118 74 0,000 0,09902414 0,10355992 ! amino acid transport GO:0006865 148 74 0,000 0,09902414 0,1035156 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,09902414 0,10347133 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,10029419 0,10475362 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,10029419 0,10470885 ! reproductive structure development GO:0048608 131 75 0,000 0,10029419 0,10466412 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,10029419 0,10461943 ! eye development GO:0001654 155 75 0,000 0,10029419 0,10457478 ! axon guidance GO:0007411 162 75 0,000 0,10029419 0,10453017 ! rhythmic process GO:0048511 142 75 0,000 0,10029419 0,10448559 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,10156249 0,10576179 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,10156249 0,10571673 ! learning or memory GO:0007611 161 76 0,000 0,10156249 0,1056717 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,10156249 0,10562672 ! regulation of blood pressure GO:0008217 134 76 0,000 0,10156249 0,10558177 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,10156249 0,10553686 ! amine catabolic process GO:0009310 136 77 0,000 0,10282904 0,10680754 ! neurotransmitter transport GO:0006836 142 77 0,000 0,10282904 0,10676215 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,10282904 0,10671679 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,10282904 0,10667148 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,10282904 0,1066262 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,10282904 0,10658097 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,10282904 0,10653577 ! regulation of catabolic process GO:0009894 173 77 0,000 0,10282904 0,1064906 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,10409383 0,10775476 ! fertilization GO:0009566 99 78 0,000 0,10409383 0,10770912 ! blood coagulation GO:0007596 151 79 0,000 0,10535688 0,10896988 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,10535688 0,10892377 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,10535688 0,10887769 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,10535688 0,10883165 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,10535688 0,10878566 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,10535688 0,1087397 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,10661819 0,10999503 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,10661819 0,1099486 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,10661819 0,10990221 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,10661819 0,10985585 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,10787775 0,1111068 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,10913557 0,11235491 ! protein import into nucleus GO:0006606 174 82 0,000 0,10913557 0,11230758 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,11039165 0,11355234 ! exocytosis GO:0006887 153 83 0,000 0,11039165 0,11350455 ! response to drug GO:0042493 149 83 0,000 0,11039165 0,1134568 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,11039165 0,11340909 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,11039165 0,11336142 ! nuclear import GO:0051170 177 83 0,000 0,11039165 0,11331378 ! inorganic anion transport GO:0015698 156 83 0,000 0,11039165 0,11326619 ! response to metal ion GO:0010038 158 84 0,000 0,111646 0,11450511 ! response to nutrient GO:0007584 135 84 0,000 0,111646 0,11445706 ! digestion GO:0007586 130 84 0,000 0,111646 0,11440905 ! regulation of ligase activity GO:0051340 147 84 0,000 0,111646 0,11436108 ! hemostasis GO:0007599 165 85 0,000 0,11289861 0,11559569 ! negative regulation of transport GO:0051051 164 85 0,000 0,11289861 0,11554726 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,11289861 0,11549888 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,11289861 0,11545053 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,11289861 0,11540222 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,11289861 0,11535396 ! cellular response to hormone stimulus GO:0032870 182 85 0,000 0,11289861 0,11530573 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,1141495 0,11653457 ! regulation of lyase activity GO:0051339 169 86 0,000 0,1141495 0,11648589 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,11539865 0,11771144 ! mitochondrion organization GO:0007005 159 87 0,000 0,11539865 0,11766232 ! alcohol catabolic process GO:0046164 142 87 0,000 0,11539865 0,11761323 ! nucleosome assembly GO:0006334 126 87 0,000 0,11539865 0,11756418 ! cellular respiration GO:0045333 143 88 0,000 0,11664608 0,11878548 ! amine biosynthetic process GO:0009309 146 88 0,000 0,11664608 0,11873599 ! sensory perception of smell GO:0007608 117 88 0,000 0,11664608 0,11868654 ! chromatin assembly GO:0031497 128 88 0,000 0,11664608 0,11863713 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,11664608 0,11858775 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,11789178 0,11980434 ! regulation of DNA binding GO:0051101 167 89 0,000 0,11789178 0,11975452 ! tube morphogenesis GO:0035239 194 89 0,000 0,11789178 0,11970475 ! cellular defense response GO:0006968 123 89 0,000 0,11789178 0,11965502 ! protein localization in nucleus GO:0034504 192 89 0,000 0,11789178 0,11960533 ! regulation of neurological system process GO:0031644 175 89 0,000 0,11789178 0,11955568 ! response to inorganic substance GO:0010035 173 90 0,000 0,11913577 0,12076709 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,11913577 0,120717 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,11913577 0,12066695 ! response to unfolded protein GO:0006986 139 90 0,000 0,11913577 0,12061694 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,11913577 0,12056698 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,12037803 0,12177372 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,12037803 0,12172332 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,12161858 0,12292685 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,12285741 0,12412765 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,12285741 0,12407633 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,12285741 0,12402506 ! vitamin metabolic process GO:0006766 153 93 0,000 0,12285741 0,12397383 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,12409453 0,12517049 ! female pregnancy GO:0007565 166 94 0,000 0,12409453 0,12511883 ! sterol metabolic process GO:0016125 166 94 0,000 0,12409453 0,12506722 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,12409453 0,12501564 ! regulation of defense response GO:0031347 171 95 0,000 0,12532994 0,12620818 ! nucleosome organization GO:0034728 143 95 0,000 0,12532994 0,12615618 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,12532994 0,12610422 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,12532994 0,1260523 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,12532994 0,12600043 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,12532994 0,1259486 ! sex differentiation GO:0007548 171 96 0,000 0,12656364 0,12713609 ! response to protein stimulus GO:0051789 158 96 0,000 0,12656364 0,12708384 ! regulation of T cell activation GO:0050863 175 96 0,000 0,12656364 0,12703163 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,12779564 0,1282155 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,12779564 0,12816287 ! transcription initiation GO:0006352 171 97 0,000 0,12779564 0,12811028 ! leukocyte differentiation GO:0002521 232 98 0,000 0,12902593 0,12929055 ! forebrain development GO:0030900 210 98 0,000 0,12902593 0,12923754 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,12902593 0,12918457 ! mRNA transport GO:0051028 185 100 0,000 0,13148142 0,13158915 ! positive regulation of immune response GO:0050778 175 100 0,000 0,13148142 0,13153526 ! hormone metabolic process GO:0042445 171 100 0,000 0,13148142 0,13148142