pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/633-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! auditory receptor cell differentiation GO:0042491 32 16 4,000 1,716E-10 4,129E-07 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 6,051E-10 7,28E-07 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 7,929E-10 6,359E-07 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 1,024E-09 6,162E-07 ! lung development GO:0030324 144 67 5,000 7,182E-09 3,456E-06 ! respiratory tube development GO:0030323 150 70 5,000 9,389E-09 3,765E-06 ! respiratory system development GO:0060541 153 72 5,000 1,115E-08 3,832E-06 ! inner ear development GO:0048839 79 50 4,000 7,868E-08 2,366E-05 ! ear development GO:0043583 103 62 4,000 2,356E-07 6,297E-05 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 1,997E-06 4,804E-04 ! interphase GO:0051325 213 98 4,000 2,329E-06 5,094E-04 ! Golgi vesicle transport GO:0048193 207 99 4,000 2,449E-06 4,909E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,012E-06 5,574E-04 ! G1 phase GO:0051318 40 19 2,000 9,071E-06 1,559E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,065E-05 1,709E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,367E-05 2,056E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,45E-05 2,053E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,82E-05 2,433E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 1,88E-05 2,381E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 2,704E-05 3,253E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 3,368E-05 3,859E-03 ! positive regulation of muscle cell differentiation GO:0051149 13 5 1,000 4,567E-05 4,995E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,567E-05 4,778E-03 ! substrate-bound cell migration, cell extension GO:0006930 6 5 1,000 4,567E-05 4,579E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,567E-05 4,396E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 4,567E-05 4,227E-03 ! neural tube patterning GO:0021532 7 5 1,000 4,567E-05 4,07E-03 ! negative regulation of secretion GO:0051048 63 35 2,000 5,977E-05 5,136E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 6,511E-05 5,402E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 6,842E-05 5,487E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 6,842E-05 5,31E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 6,842E-05 5,144E-03 ! mammary gland development GO:0030879 86 39 2,000 8,295E-05 6,048E-03 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 9,565E-05 6,768E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 9,565E-05 6,575E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 9,565E-05 6,392E-03 ! vesicle fusion GO:0006906 17 7 1,000 9,565E-05 6,22E-03 ! cell differentiation in hindbrain GO:0021533 10 7 1,000 9,565E-05 6,056E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 9,565E-05 5,901E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 9,565E-05 5,753E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 9,565E-05 5,613E-03 ! gliogenesis GO:0042063 88 41 2,000 9,646E-05 5,526E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 1,037E-04 5,803E-03 ! striated muscle cell differentiation GO:0051146 82 43 2,000 1,113E-04 6,087E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,113E-04 5,952E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,274E-04 6,661E-03 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,274E-04 6,519E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 1,274E-04 6,384E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,274E-04 6,253E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,274E-04 6,128E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,635E-04 7,714E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,635E-04 7,566E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 1,635E-04 7,423E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,635E-04 7,285E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,635E-04 7,153E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,041E-04 8,769E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,041E-04 8,615E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,041E-04 8,467E-03 ! localization within membrane GO:0051668 20 10 1,000 2,041E-04 8,323E-03 ! response to UV GO:0009411 104 53 2,000 2,081E-04 8,344E-03 ! neuron fate specification GO:0048665 17 11 1,000 2,491E-04 9,826E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,491E-04 9,667E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,491E-04 9,514E-03 ! substrate-bound cell migration GO:0006929 13 11 1,000 2,491E-04 9,365E-03 ! positive regulation of neuron differentiation GO:0045666 19 11 1,000 2,491E-04 9,221E-03 ! cardiac cell differentiation GO:0035051 31 11 1,000 2,491E-04 9,081E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 2,583E-04 9,276E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,985E-04 0,01056229 ! protein complex disassembly GO:0043241 27 12 1,000 2,985E-04 0,01040921 GO:0043624|cellular protein complex disassembly, ! focal adhesion formation GO:0048041 35 12 1,000 2,985E-04 0,01026051 ! cranial nerve development GO:0021545 20 12 1,000 2,985E-04 0,01011599 ! histone acetylation GO:0016573 26 12 1,000 2,985E-04 9,975E-03 ! gland morphogenesis GO:0022612 29 12 1,000 2,985E-04 9,839E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,985E-04 9,706E-03 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 3,474E-04 0,01114325 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 3,474E-04 0,01099662 ! lipid localization GO:0010876 28 13 1,000 3,523E-04 0,01100833 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 3,523E-04 0,0108672 ! endocrine pancreas development GO:0031018 22 13 1,000 3,523E-04 0,01072964 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,523E-04 0,01059552 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 3,523E-04 0,01046471 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 4,104E-04 0,01204315 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 4,104E-04 0,01189805 ! negative regulation of cell growth GO:0030308 132 67 2,000 4,165E-04 0,01192867 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 4,35E-04 0,01231346 ! negative regulation of cell size GO:0045792 134 69 2,000 4,541E-04 0,01270393 ! regulation of vasodilation GO:0042312 26 15 1,000 4,729E-04 0,01307909 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 5,397E-04 0,01475711 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 5,397E-04 0,0145913 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 6,109E-04 0,0163303 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 6,109E-04 0,01615085 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 6,109E-04 0,0159753 ! regulation of protein binding GO:0043393 33 17 1,000 6,109E-04 0,01580352 ! protein oligomerization GO:0051259 139 78 2,000 6,503E-04 0,01664439 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,863E-04 0,01738044 ! cell-substrate junction assembly GO:0007044 54 18 1,000 6,863E-04 0,0171994 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 6,863E-04 0,01702209 ! nerve development GO:0021675 28 18 1,000 6,863E-04 0,01684839 ! muscle cell differentiation GO:0042692 159 80 2,000 7,001E-04 0,01701527 ! response to hypoxia GO:0001666 171 81 2,000 7,259E-04 0,01746616 ! lipid phosphorylation GO:0046834 35 19 1,000 7,659E-04 0,01824581 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 7,659E-04 0,01806693 ! actin filament bundle formation GO:0051017 42 19 1,000 7,659E-04 0,01789152 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 7,659E-04 0,01771949 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 7,659E-04 0,01755073 ! response to oxygen levels GO:0070482 176 83 2,000 7,794E-04 0,01769019 ! negative regulation of transport GO:0051051 153 84 2,000 8,07E-04 0,01814604 ! negative regulation of growth GO:0045926 155 84 2,000 8,07E-04 0,01797802 ! protein amino acid acetylation GO:0006473 39 20 1,000 8,498E-04 0,01875905 ! pancreas development GO:0031016 35 20 1,000 8,498E-04 0,01858852 ! cellular response to starvation GO:0009267 33 20 1,000 8,498E-04 0,01842105 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 8,498E-04 0,01825658 ! gland development GO:0048732 206 88 2,000 9,237E-04 0,01966751 ! inactivation of MAPK activity GO:0000188 39 21 1,000 9,38E-04 0,01979675 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 9,38E-04 0,0196246 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 9,38E-04 0,01945542 ! regulation of vasoconstriction GO:0019229 39 21 1,000 9,38E-04 0,01928914 ! regulation of cell adhesion GO:0030155 212 89 2,000 9,545E-04 0,01946125 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 1,000 1,03E-03 0,02083243 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 1,03E-03 0,02065883 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 1,03E-03 0,0204881 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,03E-03 0,02032016 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,03E-03 0,02015496 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,127E-03 0,02186601 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,127E-03 0,02169108 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,127E-03 0,02151893 ! vesicle docking GO:0048278 47 24 1,000 1,228E-03 0,02325797 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,228E-03 0,02307627 ! membrane depolarization GO:0051899 39 24 1,000 1,228E-03 0,02289738 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,228E-03 0,02272125 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,333E-03 0,02447442 ! vasculogenesis GO:0001570 46 25 1,000 1,333E-03 0,024289 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,333E-03 0,02410638 ! response to starvation GO:0042594 42 25 1,000 1,333E-03 0,02392648 ! neural crest cell development GO:0014032 54 25 1,000 1,333E-03 0,02374925 GO:0014033|neural crest cell differentiation, ! regulation of blood coagulation GO:0030193 40 25 1,000 1,333E-03 0,02357462 ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,333E-03 0,02340254 ! cell cycle arrest GO:0007050 213 100 2,000 1,336E-03 0,02329772 ! macromolecular complex disassembly GO:0032984 53 26 1,000 1,442E-03 0,02495324 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 1,442E-03 0,024775 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,442E-03 0,02459929 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 1,442E-03 0,02442606 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 1,442E-03 0,02425525 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 1,442E-03 0,02408681 ! neuron fate commitment GO:0048663 48 27 1,000 1,555E-03 0,02579845 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 1,555E-03 0,02562175 ! protein amino acid acylation GO:0043543 55 27 1,000 1,555E-03 0,02544745 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 1,555E-03 0,02527551 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,793E-03 0,02895921 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 1,793E-03 0,02876614 ! regulation of coagulation GO:0050818 46 29 1,000 1,793E-03 0,02857564 ! membrane docking GO:0022406 61 30 1,000 1,919E-03 0,03037309 ! cell junction assembly GO:0034329 78 30 1,000 1,919E-03 0,03017457 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,919E-03 0,02997863 ! regulation of B cell activation GO:0050864 50 30 1,000 1,919E-03 0,02978522 ! cholesterol homeostasis GO:0042632 53 31 1,000 2,048E-03 0,03159134 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 43 31 1,000 2,048E-03 0,03139012 ! erythrocyte differentiation GO:0030218 55 31 1,000 2,048E-03 0,03119145 ! cholesterol transport GO:0030301 56 32 1,000 2,182E-03 0,03301572 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 2,182E-03 0,03280937 ! peripheral nervous system development GO:0007422 64 32 1,000 2,182E-03 0,03260559 ! hindbrain development GO:0030902 61 32 1,000 2,182E-03 0,03240432 ! formation of primary germ layer GO:0001704 72 33 1,000 2,319E-03 0,0342357 ! cell fate specification GO:0001708 52 33 1,000 2,319E-03 0,03402694 ! sterol transport GO:0015918 57 33 1,000 2,319E-03 0,03382072 ! glial cell differentiation GO:0010001 63 34 1,000 2,461E-03 0,03566846 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 2,461E-03 0,03545488 ! regulation of muscle development GO:0048634 70 35 1,000 2,606E-03 0,03732794 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 2,606E-03 0,03710707 ! neutral lipid metabolic process GO:0006638 50 35 1,000 2,606E-03 0,03688879 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 2,606E-03 0,03667307 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,606E-03 0,03645985 ! cell junction organization GO:0034330 86 36 1,000 2,756E-03 0,03832814 ! tissue remodeling GO:0048771 76 37 1,000 2,909E-03 0,04022956 ! glycerol ether metabolic process GO:0006662 53 37 1,000 2,909E-03 0,03999968 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 2,909E-03 0,0397724 ! carbohydrate homeostasis GO:0033500 53 38 1,000 3,067E-03 0,04168688 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 3,067E-03 0,04145269 ! erythrocyte homeostasis GO:0034101 64 38 1,000 3,067E-03 0,04122111 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 3,067E-03 0,0409921 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! organic ether metabolic process GO:0018904 55 39 1,000 3,228E-03 0,04290957 ! mesenchymal cell development GO:0014031 87 40 1,000 3,393E-03 0,0448575 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 3,562E-03 0,04683515 ! epithelial cell differentiation GO:0030855 79 43 1,000 3,912E-03 0,05115336 ! neural tube development GO:0021915 77 43 1,000 3,912E-03 0,05087685 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 4,277E-03 0,05532505 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 4,277E-03 0,0550292 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 4,277E-03 0,05473649 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 4,465E-03 0,05684286 ! response to insulin stimulus GO:0032868 95 46 1,000 4,465E-03 0,05654369 ! protein homooligomerization GO:0051260 76 47 1,000 4,657E-03 0,05866616 ! positive regulation of cell cycle GO:0045787 89 48 1,000 4,853E-03 0,06081367 ! Notch signaling pathway GO:0007219 96 48 1,000 4,853E-03 0,06049857 ! cellular component disassembly GO:0022411 86 48 1,000 4,853E-03 0,06018673 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 4,853E-03 0,05987808 ! endocrine system development GO:0035270 104 49 1,000 5,052E-03 0,06202156 ! regulation of ossification GO:0030278 117 50 1,000 5,256E-03 0,06418884 ! histone modification GO:0016570 91 50 1,000 5,256E-03 0,06386465 ! vesicle organization GO:0016050 107 51 1,000 5,463E-03 0,06604578 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 5,463E-03 0,06571555 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 1,000 5,673E-03 0,06791001 ! membrane fusion GO:0006944 110 52 1,000 5,673E-03 0,06757382 ! covalent chromatin modification GO:0016569 101 52 1,000 5,673E-03 0,06724095 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 5,673E-03 0,06691133 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 5,888E-03 0,06910034 ! regulation of protein polymerization GO:0032271 103 53 1,000 5,888E-03 0,0687649 ! activation of phospholipase C activity GO:0007202 103 54 1,000 6,106E-03 0,07096638 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 6,327E-03 0,07318889 ! gastrulation GO:0007369 112 55 1,000 6,327E-03 0,0728387 ! negative regulation of cell motion GO:0051271 134 55 1,000 6,327E-03 0,07249185 ! positive regulation of organelle organization GO:0010638 100 56 1,000 6,552E-03 0,07471694 ! regulation of bone remodeling GO:0046850 137 57 1,000 6,781E-03 0,07696206 ! positive regulation of cell migration GO:0030335 126 57 1,000 6,781E-03 0,07660073 ! lipid modification GO:0030258 97 57 1,000 6,781E-03 0,07624278 ! regulation of phospholipase activity GO:0010517 106 57 1,000 6,781E-03 0,07588817 ! regulation of tissue remodeling GO:0034103 140 58 1,000 7,014E-03 0,07812638 ! regulation of endocytosis GO:0030100 91 58 1,000 7,014E-03 0,07776635 ! positive regulation of lipase activity GO:0060193 108 58 1,000 7,014E-03 0,07740962 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 7,49E-03 0,0822822 ! regulation of protein complex assembly GO:0043254 117 61 1,000 7,733E-03 0,08456767 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 7,733E-03 0,08418501 ! regulation of homeostatic process GO:0032844 134 62 1,000 7,979E-03 0,08647963 ! cell redox homeostasis GO:0045454 102 64 1,000 8,483E-03 0,09152924 ! positive regulation of cell motion GO:0051272 146 64 1,000 8,483E-03 0,09112063 ! myeloid cell differentiation GO:0030099 111 65 1,000 8,741E-03 0,0934662 ! actin filament organization GO:0007015 148 66 1,000 9,001E-03 0,09582798 ! cell projection assembly GO:0030031 120 66 1,000 9,001E-03 0,09540583 ! homeostasis of number of cells GO:0048872 114 67 1,000 9,265E-03 0,09777485 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 9,265E-03 0,09734788 ! regulation of lipase activity GO:0060191 130 68 1,000 9,533E-03 0,09972384 ! cell cycle checkpoint GO:0000075 137 69 1,000 9,804E-03 0,1021149 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,01035629 0,10740184 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01063748 0,10984454 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01074548 0,11048556 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01074548 0,1100154 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01074548 0,10954924 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01074548 0,109087 ! neuron fate determination GO:0048664 7 5 0,000 0,01074548 0,10862866 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01074548 0,10817414 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01074548 0,10772342 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01074548 0,10727643 ! polyol transport GO:0015791 12 5 0,000 0,01074548 0,10683314 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01074548 0,1063935 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01074548 0,10595746 ! response to superoxide GO:0000303 10 5 0,000 0,01074548 0,10552498 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01074548 0,10509602 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01074548 0,10467053 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01074548 0,10424847 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01074548 0,1038298 ! female meiosis GO:0007143 7 5 0,000 0,01074548 0,10341448 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01074548 0,10300247 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01074548 0,10259373 ! cobalt ion transport GO:0006824 11 5 0,000 0,01074548 0,10218822 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01074548 0,10178591 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01074548 0,10138675 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01074548 0,1009907 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01074548 0,10059774 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01074548 0,10020783 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01074548 0,09982093 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01074548 0,099437 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01074548 0,09905602 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01074548 0,09867794 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01074548 0,09830274 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01074548 0,09793038 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01074548 0,09756083 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01074548 0,09719406 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01074548 0,09683004 ! negative chemotaxis GO:0050919 14 5 0,000 0,01074548 0,09646873 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01074548 0,09611011 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01074548 0,09575415 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01074548 0,09540081 ! behavioral response to pain GO:0048266 9 5 0,000 0,01074548 0,09505007 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01074548 0,09470191 ! Notch receptor processing GO:0007220 8 5 0,000 0,01074548 0,09435628 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01074548 0,09401316 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01074548 0,09367254 ! micturition GO:0060073 9 5 0,000 0,01074548 0,09333437 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01074548 0,09299863 ! copulation GO:0007620 9 5 0,000 0,01074548 0,0926653 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01074548 0,09233436 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01074548 0,09200577 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01074548 0,0916795 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01074548 0,09135555 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01074548 0,09103387 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01074548 0,09071446 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01074548 0,09039727 ! grooming behavior GO:0007625 6 5 0,000 0,01074548 0,0900823 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01074548 0,08976951 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01074548 0,08945889 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01074548 0,08915041 ! response to protozoan GO:0001562 10 5 0,000 0,01074548 0,08884406 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01074548 0,08853979 ! lymph vessel development GO:0001945 10 5 0,000 0,01074548 0,08823761 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01074548 0,08793748 ! endochondral ossification GO:0001958 16 5 0,000 0,01074548 0,08763939 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01074548 0,08734331 ! parathyroid gland development GO:0060017 13 5 0,000 0,01074548 0,08704923 ! anagen GO:0042640 6 5 0,000 0,01074548 0,08675711 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01074548 0,08646696 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01074548 0,08617873 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01074548 0,08589243 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01074548 0,08560801 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01074548 0,08532548 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01074548 0,0850448 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01074548 0,08476597 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01074548 0,08448895 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01074548 0,08421375 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01074548 0,08394032 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01074548 0,08366867 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01074548 0,08339877 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01074548 0,08313061 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01074548 0,08286417 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01074548 0,08259943 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01074548 0,08233637 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01074548 0,08207498 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01074548 0,08181525 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01074548 0,08155716 ! histidine catabolic process GO:0006548 6 5 0,000 0,01074548 0,08130069 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01074548 0,08104583 ! microvillus organization GO:0032528 7 5 0,000 0,01074548 0,08079256 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01074548 0,08054087 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01074548 0,08029075 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01074548 0,08004217 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01074548 0,07979512 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01074548 0,0795496 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01074548 0,07930558 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01074548 0,07906306 ! polyol catabolic process GO:0046174 7 5 0,000 0,01074548 0,07882201 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01074548 0,07858243 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01074548 0,0783443 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01074548 0,07810761 ! muscle cell migration GO:0014812 8 5 0,000 0,01074548 0,07787235 ! mitochondrial fission GO:0000266 8 5 0,000 0,01074548 0,0776385 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01074548 0,07740605 ! mRNA transcription GO:0009299 9 5 0,000 0,01074548 0,07717499 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01074548 0,0769453 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01074548 0,07671697 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01074548 0,07649 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01074548 0,07626437 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01074548 0,07604006 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01074548 0,07581707 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01074548 0,07559538 ! response to food GO:0032094 6 5 0,000 0,01074548 0,07537499 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01074548 0,07515587 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01074548 0,07493803 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01074548 0,07472145 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01074548 0,07450611 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01074548 0,07429201 ! forebrain neuron development GO:0021884 13 5 0,000 0,01074548 0,07407914 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01074548 0,07386749 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01074548 0,07365704 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01074548 0,07344778 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01074548 0,07323972 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01074548 0,07303283 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01074548 0,0728271 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01074548 0,07262253 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01074548 0,0724191 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01074548 0,07221682 ! basic amino acid transport GO:0015802 11 5 0,000 0,01074548 0,07201565 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01074548 0,07181561 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01074548 0,07161668 ! depyrimidination GO:0045008 10 5 0,000 0,01074548 0,07141884 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01074548 0,07122209 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01074548 0,07102643 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01074548 0,07083184 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01074548 0,07063831 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01074548 0,07044583 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01074548 0,0702544 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01074548 0,07006401 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01074548 0,06987465 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01074548 0,06968631 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01074548 0,06949898 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01074548 0,06931265 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01074548 0,06912733 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01074548 0,06894299 ! response to arsenic GO:0046685 10 5 0,000 0,01074548 0,06875963 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01074548 0,06857724 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01074548 0,06839582 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01074548 0,06821536 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01074548 0,06803584 ! response to cadmium ion GO:0046686 7 5 0,000 0,01074548 0,06785727 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01074548 0,06767963 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01074548 0,06750292 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01074548 0,06732714 ! decidualization GO:0046697 11 5 0,000 0,01074548 0,06715226 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01074548 0,06697829 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01074548 0,06680522 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01074548 0,06663304 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01074548 0,06646175 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01074548 0,06629133 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01074548 0,06612179 ! embryonic cleavage GO:0040016 6 5 0,000 0,01074548 0,06595311 ! peroxisome fission GO:0016559 5 5 0,000 0,01074548 0,06578529 ! histone demethylation GO:0016577 10 5 0,000 0,01074548 0,06561833 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01074548 0,0654522 ! mitotic recombination GO:0006312 9 5 0,000 0,01074548 0,06528692 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01074548 0,06512247 ! metaphase plate congression GO:0051310 7 5 0,000 0,01074548 0,06495884 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01074548 0,06479604 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01074548 0,06463405 ! enteric nervous system development GO:0048484 8 5 0,000 0,01074548 0,06447287 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01074548 0,06431249 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01074548 0,0641529 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01074548 0,06399411 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01074548 0,0638361 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01074548 0,06367887 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01074548 0,06352241 ! plasminogen activation GO:0031639 5 5 0,000 0,01074548 0,06336672 ! B cell homeostasis GO:0001782 13 5 0,000 0,01074548 0,06321179 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01074548 0,06305761 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01074548 0,06290419 ! metaphase GO:0051323 8 5 0,000 0,01074548 0,06275151 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01074548 0,06259956 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01074548 0,06244836 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01074548 0,06229788 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01074548 0,06214813 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01074548 0,06199909 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01074548 0,06185077 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01074548 0,06170315 ! response to redox state GO:0051775 5 5 0,000 0,01074548 0,06155624 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01074548 0,06141002 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01074548 0,0612645 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01074548 0,06111967 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01074548 0,06097552 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01074548 0,06083205 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01074548 0,06068925 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01074548 0,06054712 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01074548 0,06040565 ! striatum development GO:0021756 9 5 0,000 0,01074548 0,06026485 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01074548 0,0601247 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01074548 0,0599852 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01074548 0,05984634 ! glial cell migration GO:0008347 11 5 0,000 0,01074548 0,05970813 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01074548 0,05957055 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01074548 0,05943361 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01074548 0,05929729 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01074548 0,0591616 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01074548 0,05902653 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01074548 0,05889207 ! neuroprotection GO:0043526 6 5 0,000 0,01074548 0,05875823 ! neural plate development GO:0001840 8 5 0,000 0,01074548 0,05862499 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01074548 0,05849235 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01074548 0,05836032 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01074548 0,05822887 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01074548 0,05809802 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01074548 0,05796776 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01074548 0,05783808 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01074548 0,05770897 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01074548 0,05758045 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01074548 0,05745249 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01074548 0,0573251 ! spindle assembly GO:0051225 6 5 0,000 0,01074548 0,05719827 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01074548 0,05707201 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01074548 0,0569463 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01074548 0,05682114 ! drug metabolic process GO:0017144 6 5 0,000 0,01074548 0,05669654 ! stem cell division GO:0017145 11 5 0,000 0,01074548 0,05657247 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01074548 0,05644895 ! organ regeneration GO:0031100 7 5 0,000 0,01074548 0,05632597 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01074548 0,05620352 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01074548 0,05608161 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01074548 0,05596022 ! exocytosis GO:0006887 133 74 1,000 0,01120994 0,05825295 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01150118 0,05963756 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,01150118 0,05950931 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01209358 0,06244024 ! blood coagulation GO:0007596 146 78 1,000 0,01239472 0,06385802 GO:0050817|coagulation, ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01269913 0,06528655 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01269913 0,06514735 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01288089 0,0659392 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01288089 0,0657992 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01288089 0,06565979 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01288089 0,06552098 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01288089 0,06538275 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01288089 0,0652451 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01288089 0,06510803 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01288089 0,06497154 ! sleep GO:0030431 13 6 0,000 0,01288089 0,06483561 ! response to oxygen radical GO:0000305 11 6 0,000 0,01288089 0,06470026 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01288089 0,06456546 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01288089 0,06443123 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01288089 0,06429756 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01288089 0,06416444 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01288089 0,06403187 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01288089 0,06389984 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01288089 0,06376836 ! forebrain regionalization GO:0021871 8 6 0,000 0,01288089 0,06363742 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01288089 0,06350701 ! male meiosis GO:0007140 7 6 0,000 0,01288089 0,06337714 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01288089 0,0632478 ! response to zinc ion GO:0010043 9 6 0,000 0,01288089 0,06311899 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01288089 0,0629907 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01288089 0,06286293 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01288089 0,06273567 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01288089 0,06260893 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01288089 0,06248271 ! malate metabolic process GO:0006108 11 6 0,000 0,01288089 0,06235699 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01288089 0,06223177 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01288089 0,06210706 ! protein refolding GO:0042026 15 6 0,000 0,01288089 0,06198285 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01288089 0,06185913 ! opsonization GO:0008228 8 6 0,000 0,01288089 0,0617359 ! mating behavior GO:0007617 7 6 0,000 0,01288089 0,06161317 ! neuron remodeling GO:0016322 15 6 0,000 0,01288089 0,06149092 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01288089 0,06136915 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01288089 0,06124787 ! equilibrioception GO:0050957 14 6 0,000 0,01288089 0,06112707 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01288089 0,06100674 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01288089 0,06088688 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01288089 0,0607675 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01288089 0,06064858 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01288089 0,06053012 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01288089 0,06041213 ! toxin metabolic process GO:0009404 11 6 0,000 0,01288089 0,0602946 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01288089 0,06017752 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01288089 0,0600609 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01288089 0,05994472 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01288089 0,059829 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01288089 0,05971372 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01288089 0,05959889 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01288089 0,0594845 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01288089 0,05937054 ! thymic T cell selection GO:0045061 12 6 0,000 0,01288089 0,05925702 ! protein lipoylation GO:0009249 10 6 0,000 0,01288089 0,05914394 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01288089 0,05903128 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01288089 0,05891905 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01288089 0,05880725 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01288089 0,05869588 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01288089 0,05858492 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01288089 0,05847438 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01288089 0,05836426 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01288089 0,05825455 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01288089 0,05814526 ! hyperosmotic response GO:0006972 9 6 0,000 0,01288089 0,05803637 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01288089 0,05792789 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01288089 0,05781982 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01288089 0,05771215 ! urea metabolic process GO:0019627 7 6 0,000 0,01288089 0,05760488 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01288089 0,057498 ! neutrophil activation GO:0042119 8 6 0,000 0,01288089 0,05739152 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01288089 0,05728544 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01288089 0,05717975 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01288089 0,05707444 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01288089 0,05696953 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01288089 0,056865 ! neuron apoptosis GO:0051402 9 6 0,000 0,01288089 0,05676085 ! nucleoside salvage GO:0043174 9 6 0,000 0,01288089 0,05665708 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01288089 0,05655369 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01288089 0,05645068 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01288089 0,05634804 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01288089 0,05624578 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01288089 0,05614388 ! carnitine transport GO:0015879 10 6 0,000 0,01288089 0,05604236 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01288089 0,0559412 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01288089 0,0558404 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01288089 0,05573997 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01288089 0,0556399 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01288089 0,05554018 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01288089 0,05544083 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01288089 0,05534183 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01288089 0,05524318 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01288089 0,05514488 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01288089 0,05504693 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01288089 0,05494933 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01288089 0,05485208 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01288089 0,05475516 ! neural nucleus development GO:0048857 14 6 0,000 0,01288089 0,05465859 ! response to UV-C GO:0010225 11 6 0,000 0,01288089 0,05456236 ! astrocyte development GO:0014002 15 6 0,000 0,01288089 0,05446647 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01288089 0,05437092 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01288089 0,0542757 ! interaction with symbiont GO:0051702 13 6 0,000 0,01288089 0,05418081 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01288089 0,05408625 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01288089 0,05399203 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01288089 0,05389813 ! response to copper ion GO:0046688 10 6 0,000 0,01288089 0,05380455 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01288089 0,0537113 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01288089 0,05361838 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01288089 0,05352577 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01288089 0,05343349 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01288089 0,05334152 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01288089 0,05324987 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01288089 0,05315853 ! hair follicle maturation GO:0048820 7 6 0,000 0,01288089 0,0530675 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01288089 0,05297679 ! Schwann cell development GO:0014044 15 6 0,000 0,01288089 0,05288639 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01288089 0,05279629 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01288089 0,0527065 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01288089 0,05261702 ! subpallium development GO:0021544 10 6 0,000 0,01288089 0,05252784 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01288089 0,05243896 ! histone ubiquitination GO:0016574 8 6 0,000 0,01288089 0,05235038 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01288089 0,0522621 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01288089 0,05217411 ! G2 phase GO:0051319 16 6 0,000 0,01288089 0,05208642 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01288089 0,05199903 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01288089 0,05191193 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01288089 0,05182512 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01288089 0,0517386 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01288089 0,05165237 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01288089 0,05156643 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01288089 0,05148077 ! receptor internalization GO:0031623 10 6 0,000 0,01288089 0,05139539 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01288089 0,0513103 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01288089 0,05122549 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01288089 0,05114096 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01288089 0,05105671 ! protein deubiquitination GO:0016579 14 6 0,000 0,01288089 0,05097273 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01288089 0,05088904 ! protein destabilization GO:0031648 9 6 0,000 0,01288089 0,05080561 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01288089 0,05072246 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01288089 0,05063958 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01288089 0,05055697 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01288089 0,05047463 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01288089 0,05039256 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01288089 0,05031075 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01288089 0,05022921 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01288089 0,05014793 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01288089 0,05006692 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01288089 0,04998617 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01288089 0,04990567 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01288089 0,04982544 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01288089 0,04974546 ! catecholamine transport GO:0051937 9 6 0,000 0,01288089 0,04966574 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01288089 0,04958628 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01288089 0,04950707 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01288089 0,04942811 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01288089 0,0493494 ! maternal placenta development GO:0001893 12 6 0,000 0,01288089 0,04927094 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01288089 0,04919273 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01288089 0,04911477 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01288089 0,04903706 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01288089 0,04895959 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01288089 0,04888237 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01288089 0,04880539 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,0133177 0,05038113 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,0133177 0,05030204 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,0133177 0,05022319 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01363184 0,05132739 ! hemostasis GO:0007599 158 84 1,000 0,01426972 0,05364525 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01459345 0,05477665 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,01492034 0,0559164 ! tRNA transcription GO:0009304 14 7 0,000 0,01501176 0,05617155 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01501176 0,05608432 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01501176 0,05599737 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01501176 0,05591069 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01501176 0,05582427 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01501176 0,05573813 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01501176 0,05565224 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01501176 0,05556662 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01501176 0,05548127 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01501176 0,05539617 ! prostate gland development GO:0030850 13 7 0,000 0,01501176 0,05531134 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01501176 0,05522677 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01501176 0,05514245 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01501176 0,05505839 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01501176 0,05497459 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01501176 0,05489104 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01501176 0,05480775 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01501176 0,0547247 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01501176 0,05464191 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01501176 0,05455937 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01501176 0,05447708 ! glycolipid transport GO:0046836 10 7 0,000 0,01501176 0,05439504 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01501176 0,05431324 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01501176 0,05423169 ! neuron adhesion GO:0007158 12 7 0,000 0,01501176 0,05415038 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01501176 0,05406932 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01501176 0,0539885 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01501176 0,05390792 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01501176 0,05382758 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01501176 0,05374748 ! mRNA stabilization GO:0048255 18 7 0,000 0,01501176 0,05366762 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01501176 0,05358799 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01501176 0,0535086 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01501176 0,05342945 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01501176 0,05335052 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01501176 0,05327184 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01501176 0,05319338 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01501176 0,05311515 ! lipoprotein transport GO:0042953 14 7 0,000 0,01501176 0,05303716 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01501176 0,05295939 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01501176 0,05288185 ! rhythmic behavior GO:0007622 15 7 0,000 0,01501176 0,05280454 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01501176 0,05272745 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01501176 0,05265059 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01501176 0,05257395 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01501176 0,05249754 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01501176 0,05242134 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01501176 0,05234537 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01501176 0,05226962 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01501176 0,05219408 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01501176 0,05211877 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01501176 0,05204367 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01501176 0,05196878 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01501176 0,05189412 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01501176 0,05181966 ! spinal cord patterning GO:0021511 13 7 0,000 0,01501176 0,05174542 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01501176 0,0516714 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01501176 0,05159758 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01501176 0,05152397 ! adrenal gland development GO:0030325 17 7 0,000 0,01501176 0,05145058 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01501176 0,05137739 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01501176 0,05130441 ! ovulation GO:0030728 9 7 0,000 0,01501176 0,05123164 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01501176 0,05115907 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01501176 0,05108671 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01501176 0,05101456 ! microtubule nucleation GO:0007020 20 7 0,000 0,01501176 0,0509426 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01501176 0,05087085 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01501176 0,0507993 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01501176 0,05072796 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01501176 0,05065681 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01501176 0,05058586 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01501176 0,05051511 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01501176 0,05044456 ! galactose metabolic process GO:0006012 13 7 0,000 0,01501176 0,05037421 ! response to dietary excess GO:0002021 8 7 0,000 0,01501176 0,05030405 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01501176 0,05023408 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01501176 0,05016431 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01501176 0,05009474 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01501176 0,05002535 ! organ growth GO:0035265 15 7 0,000 0,01501176 0,04995616 ! purine salvage GO:0043101 10 7 0,000 0,01501176 0,04988716 ! nucleoside transport GO:0015858 8 7 0,000 0,01501176 0,04981835 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01501176 0,04974973 ! parturition GO:0007567 14 7 0,000 0,01501176 0,0496813 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01501176 0,04961306 ! rRNA modification GO:0000154 14 7 0,000 0,01501176 0,049545 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01501176 0,04947713 ! spindle checkpoint GO:0031577 15 7 0,000 0,01501176 0,04940945 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01501176 0,04934195 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01501176 0,04927463 ! macrophage differentiation GO:0030225 11 7 0,000 0,01501176 0,0492075 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01501176 0,04914055 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01501176 0,04907378 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01501176 0,0490072 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01501176 0,04894079 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01501176 0,04887457 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01501176 0,04880852 ! fibrinolysis GO:0042730 10 7 0,000 0,01501176 0,04874265 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01501176 0,04867696 ! eating behavior GO:0042755 7 7 0,000 0,01501176 0,04861145 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01501176 0,04854611 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01501176 0,04848095 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01501176 0,04841596 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01501176 0,04835114 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01501176 0,0482865 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01501176 0,04822204 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01501176 0,04815774 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01501176 0,04809362 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01501176 0,04802966 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01501176 0,04796588 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01501176 0,04790226 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01501176 0,04783881 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01501176 0,04777554 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01501176 0,04771242 ! regulation of meiosis GO:0040020 12 7 0,000 0,01501176 0,04764948 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01501176 0,0475867 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01501176 0,04752409 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01501176 0,04746164 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01501176 0,04739935 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01501176 0,04733723 ! transcription termination GO:0006353 13 7 0,000 0,01501176 0,04727527 ! response to tumor cell GO:0002347 13 7 0,000 0,01501176 0,04721347 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01501176 0,04715183 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01501176 0,04709036 ! anaphase GO:0051322 17 7 0,000 0,01501176 0,04702904 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01501176 0,04696789 ! axonal fasciculation GO:0007413 18 7 0,000 0,01501176 0,04690689 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01501176 0,04684605 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01501176 0,04678537 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01501176 0,04672485 ! diuresis GO:0030146 12 7 0,000 0,01501176 0,04666448 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01501176 0,04660426 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01501176 0,04654421 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01501176 0,04648431 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01501176 0,04642456 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01501176 0,04636496 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01501176 0,04630552 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01501176 0,04624623 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01501176 0,04618709 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01501176 0,0461281 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01501176 0,04606927 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01501176 0,04601058 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01501176 0,04595204 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,01501176 0,04589365 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01501176 0,04583541 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01501176 0,04577732 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01501176 0,04571937 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01501176 0,04566157 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01501176 0,04560392 ! adult feeding behavior GO:0008343 9 7 0,000 0,01501176 0,04554641 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01501176 0,04548905 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01501176 0,04543183 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01501176 0,04537476 ! muscle adaptation GO:0043500 14 7 0,000 0,01501176 0,04531782 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01501176 0,04526103 ! retina homeostasis GO:0001895 12 7 0,000 0,01501176 0,04520439 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01501176 0,04514788 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01501176 0,04509152 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01501176 0,04503529 ! protein prenylation GO:0018342 18 7 0,000 0,01501176 0,04497921 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01501176 0,04492327 ! ossification GO:0001503 188 90 1,000 0,01625927 0,04859602 ! bone development GO:0060348 189 91 1,000 0,01660177 0,04955813 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01713811 0,05109577 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01713811 0,05103254 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01713811 0,05096946 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01713811 0,05090653 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01713811 0,05084376 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01713811 0,05078115 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01713811 0,05071868 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01713811 0,05065638 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01713811 0,05059422 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01713811 0,05053222 ! meiotic prophase I GO:0007128 13 8 0,000 0,01713811 0,05047037 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01713811 0,05040867 ! oligopeptide transport GO:0006857 15 8 0,000 0,01713811 0,05034712 ! UTP metabolic process GO:0046051 8 8 0,000 0,01713811 0,05028572 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01713811 0,05022447 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01713811 0,05016337 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01713811 0,05010242 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01713811 0,05004161 ! succinate metabolic process GO:0006105 14 8 0,000 0,01713811 0,04998096 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01713811 0,04992045 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01713811 0,04986008 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01713811 0,04979987 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01713811 0,0497398 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01713811 0,04967987 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01713811 0,04962008 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01713811 0,04956045 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01713811 0,04950095 ! reflex GO:0060004 16 8 0,000 0,01713811 0,0494416 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01713811 0,04938238 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01713811 0,04932331 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01713811 0,04926439 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01713811 0,0492056 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01713811 0,04914695 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01713811 0,04908844 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01713811 0,04903007 ! pigment granule organization GO:0048753 16 8 0,000 0,01713811 0,04897184 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01713811 0,04891375 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01713811 0,04885579 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01713811 0,04879798 ! histidine metabolic process GO:0006547 16 8 0,000 0,01713811 0,0487403 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01713811 0,04868275 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01713811 0,04862534 ! glycine catabolic process GO:0006546 13 8 0,000 0,01713811 0,04856807 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01713811 0,04851093 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01713811 0,04845393 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01713811 0,04839705 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01713811 0,04834032 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01713811 0,04828371 ! melanin metabolic process GO:0006582 15 8 0,000 0,01713811 0,04822724 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01713811 0,0481709 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01713811 0,04811469 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01713811 0,04805861 ! macrophage activation GO:0042116 12 8 0,000 0,01713811 0,04800267 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01713811 0,04794685 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01713811 0,04789116 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01713811 0,0478356 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01713811 0,04778017 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01713811 0,04772487 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,01713811 0,0476697 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01713811 0,04761465 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01713811 0,04755974 ! osteoblast development GO:0002076 16 8 0,000 0,01713811 0,04750494 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01713811 0,04745028 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01713811 0,04739574 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01713811 0,04734132 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01713811 0,04728703 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01713811 0,04723286 ! response to UV-B GO:0010224 16 8 0,000 0,01713811 0,04717882 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01713811 0,0471249 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01713811 0,04707111 ! intermediate filament organization GO:0045109 12 8 0,000 0,01713811 0,04701743 ! cellular extravasation GO:0045123 12 8 0,000 0,01713811 0,04696388 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01713811 0,04691046 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01713811 0,04685715 ! response to antibiotic GO:0046677 11 8 0,000 0,01713811 0,04680396 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01713811 0,0467509 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01713811 0,04669795 ! DNA topological change GO:0006265 12 8 0,000 0,01713811 0,04664512 ! response to tropane GO:0014073 15 8 0,000 0,01713811 0,04659242 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01713811 0,04653983 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01713811 0,04648736 ! melanosome transport GO:0032402 13 8 0,000 0,01713811 0,04643501 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01713811 0,04638278 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01713811 0,04633066 ! mast cell activation GO:0045576 14 8 0,000 0,01713811 0,04627866 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01713811 0,04622678 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01713811 0,04617502 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01713811 0,04612337 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01713811 0,04607183 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01713811 0,04602041 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01713811 0,04596911 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01713811 0,04591792 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01713811 0,04586684 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01713811 0,04581588 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01713811 0,04576503 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01713811 0,04571429 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01713811 0,04566367 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01713811 0,04561315 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01713811 0,04556275 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01713811 0,04551246 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01713811 0,04546228 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01713811 0,04541221 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01713811 0,04536226 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01713811 0,04531241 ! hormone catabolic process GO:0042447 17 8 0,000 0,01713811 0,04526267 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01713811 0,04521304 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01713811 0,04516352 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01713811 0,0451141 ! ATP catabolic process GO:0006200 11 8 0,000 0,01713811 0,0450648 ! blastocyst growth GO:0001832 19 8 0,000 0,01713811 0,0450156 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01713811 0,04496651 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01713811 0,04491753 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01713811 0,04486865 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01713811 0,04481988 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01713811 0,04477122 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01713811 0,04472266 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01713811 0,0446742 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01713811 0,04462586 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01713811 0,04457761 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01713811 0,04452947 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01713811 0,04448144 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01713811 0,0444335 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01713811 0,04438567 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01713811 0,04433795 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01713811 0,04429032 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01713811 0,0442428 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01713811 0,04419538 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,017296 0,04455478 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,017296 0,04450713 ! regulation of membrane potential GO:0042391 164 93 1,000 0,017296 0,04445958 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,017296 0,04441213 ! regulation of developmental growth GO:0048638 15 9 0,000 0,01925993 0,04940235 ! axon extension GO:0048675 15 9 0,000 0,01925993 0,04934973 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,01925993 0,04929723 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01925993 0,04924485 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,01925993 0,04919257 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01925993 0,0491404 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,01925993 0,04908835 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,01925993 0,0490364 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,01925993 0,04898457 ! phosphate transport GO:0006817 19 9 0,000 0,01925993 0,04893284 ! reproductive behavior GO:0019098 19 9 0,000 0,01925993 0,04888122 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01925993 0,04882972 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,01925993 0,04877832 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01925993 0,04872702 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,01925993 0,04867584 ! GTP metabolic process GO:0046039 9 9 0,000 0,01925993 0,04862476 ! RNA methylation GO:0001510 15 9 0,000 0,01925993 0,0485738 ! elastic fiber assembly GO:0048251 15 9 0,000 0,01925993 0,04852293 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,01925993 0,04847218 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,01925993 0,04842153 ! artery development GO:0060840 24 9 0,000 0,01925993 0,04837098 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,01925993 0,04832054 ! regulation of glycolysis GO:0006110 21 9 0,000 0,01925993 0,04827021 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,01925993 0,04821998 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,01925993 0,04816986 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,01925993 0,04811983 ! chemosensory behavior GO:0007635 20 9 0,000 0,01925993 0,04806992 ! microtubule bundle formation GO:0001578 21 9 0,000 0,01925993 0,0480201 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01925993 0,04797039 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,01925993 0,04792079 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01925993 0,04787128 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,01925993 0,04782188 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,01925993 0,04777258 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,01925993 0,04772338 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01925993 0,04767428 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01925993 0,04762528 ! protein targeting to ER GO:0045047 22 9 0,000 0,01925993 0,04757639 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,01925993 0,04752759 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,01925993 0,04747889 ! T cell selection GO:0045058 23 9 0,000 0,01925993 0,0474303 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,01925993 0,0473818 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01925993 0,0473334 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,01925993 0,0472851 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01925993 0,0472369 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01925993 0,0471888 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01925993 0,04714079 ! mannose metabolic process GO:0006013 13 9 0,000 0,01925993 0,04709289 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,01925993 0,04704508 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,01925993 0,04699736 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,01925993 0,04694975 ! receptor clustering GO:0043113 18 9 0,000 0,01925993 0,04690223 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,01925993 0,0468548 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01925993 0,04680748 ! ruffle organization GO:0031529 15 9 0,000 0,01925993 0,04676024 ! retinol metabolic process GO:0042572 18 9 0,000 0,01925993 0,04671311 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,01925993 0,04666606 ! behavioral fear response GO:0001662 22 9 0,000 0,01925993 0,04661912 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,01925993 0,04657226 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,01925993 0,0465255 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,01925993 0,04647884 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,01925993 0,04643227 ! oligodendrocyte development GO:0014003 10 9 0,000 0,01925993 0,04638579 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,01925993 0,0463394 ! segment specification GO:0007379 13 9 0,000 0,01925993 0,04629311 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01925993 0,04624691 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,01925993 0,0462008 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01925993 0,04615478 ! response to amine stimulus GO:0014075 13 9 0,000 0,01925993 0,04610886 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01925993 0,04606302 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,01925993 0,04601728 ! erythrocyte development GO:0048821 15 9 0,000 0,01925993 0,04597163 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01925993 0,04592607 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,01925993 0,04588059 ! renal water homeostasis GO:0003091 14 9 0,000 0,01925993 0,04583521 ! postreplication repair GO:0006301 22 9 0,000 0,01925993 0,04578992 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,01925993 0,04574472 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,01925993 0,04569961 ! icosanoid secretion GO:0032309 15 9 0,000 0,01925993 0,04565458 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,01925993 0,04560965 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01925993 0,0455648 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,01925993 0,04552004 ! regulation of cell division GO:0051302 15 9 0,000 0,01925993 0,04547537 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,01925993 0,04543079 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,01925993 0,04538629 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01925993 0,04534188 ! sterol catabolic process GO:0016127 11 9 0,000 0,01925993 0,04529756 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01925993 0,04525332 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,01925993 0,04520917 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,01925993 0,04516511 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,01925993 0,04512113 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,01925993 0,04507724 ! musculoskeletal movement GO:0050881 14 9 0,000 0,01925993 0,04503343 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,01925993 0,04498971 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,01925993 0,04494607 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01925993 0,04490252 ! purine base metabolic process GO:0006144 21 9 0,000 0,01925993 0,04485905 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,01925993 0,04481567 ! pigment granule transport GO:0051904 17 9 0,000 0,01925993 0,04477237 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,01925993 0,04472915 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,01925993 0,04468602 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,01925993 0,04464297 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01925993 0,0446 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01925993 0,04455712 ! mitochondrion localization GO:0051646 15 9 0,000 0,01925993 0,04451431 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,01945142 0,04491375 GO:0060538|skeletal muscle organ development, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02137725 0,04931319 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02137725 0,04926596 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02137725 0,04921881 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02137725 0,04917176 ! synapsis GO:0007129 13 10 0,000 0,02137725 0,04912479 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02137725 0,04907792 ! N-glycan processing GO:0006491 20 10 0,000 0,02137725 0,04903113 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02137725 0,04898444 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02137725 0,04893783 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02137725 0,04889131 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02137725 0,04884488 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02137725 0,04879854 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02137725 0,04875228 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02137725 0,04870612 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02137725 0,04866004 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02137725 0,04861404 ! androgen metabolic process GO:0008209 17 10 0,000 0,02137725 0,04856814 ! phospholipid efflux GO:0033700 16 10 0,000 0,02137725 0,04852232 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02137725 0,04847659 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02137725 0,04843094 ! lung alveolus development GO:0048286 26 10 0,000 0,02137725 0,04838538 ! pathogenesis GO:0009405 13 10 0,000 0,02137725 0,04833991 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02137725 0,04829452 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02137725 0,04824921 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02137725 0,04820399 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02137725 0,04815886 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02137725 0,04811381 ! endoderm development GO:0007492 16 10 0,000 0,02137725 0,04806884 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02137725 0,04802396 ! arginine catabolic process GO:0006527 13 10 0,000 0,02137725 0,04797916 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02137725 0,04793444 ! proline metabolic process GO:0006560 13 10 0,000 0,02137725 0,04788981 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02137725 0,04784526 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02137725 0,0478008 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02137725 0,04775642 ! V(D)J recombination GO:0033151 28 10 0,000 0,02137725 0,04771211 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02137725 0,0476679 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02137725 0,04762376 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02137725 0,0475797 ! B cell proliferation GO:0042100 18 10 0,000 0,02137725 0,04753573 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02137725 0,04749184 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02137725 0,04744803 ! multicellular organism growth GO:0035264 18 10 0,000 0,02137725 0,04740429 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02137725 0,04736064 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02137725 0,04731707 ! epithelial cell development GO:0002064 20 10 0,000 0,02137725 0,04727358 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02137725 0,04723017 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02137725 0,04718684 ! macroautophagy GO:0016236 17 10 0,000 0,02137725 0,04714359 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02137725 0,04710042 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02137725 0,04705733 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02137725 0,04701431 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02137725 0,04697138 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02137725 0,04692852 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02137725 0,04688574 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02137725 0,04684304 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02137725 0,04680042 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02137725 0,04675787 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02137725 0,0467154 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02137725 0,04667301 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02137725 0,0466307 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02137725 0,04658846 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02137725 0,0465463 ! response to dsRNA GO:0043331 20 10 0,000 0,02137725 0,04650421 ! DNA ligation GO:0006266 19 10 0,000 0,02137725 0,0464622 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02137725 0,04642027 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02137725 0,04637841 ! melanosome localization GO:0032400 16 10 0,000 0,02137725 0,04633663 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02137725 0,04629492 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02137725 0,04625329 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02137725 0,04621173 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02137725 0,04617025 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02137725 0,04612884 ! mRNA cleavage GO:0006379 17 10 0,000 0,02137725 0,04608751 ! protein sumoylation GO:0016925 15 10 0,000 0,02137725 0,04604625 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02137725 0,04600506 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02137725 0,04596395 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02137725 0,04592291 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02137725 0,04588194 ! salivary gland development GO:0007431 27 10 0,000 0,02137725 0,04584105 ! prophase GO:0051324 15 10 0,000 0,02137725 0,04580023 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02137725 0,04575948 ! apical protein localization GO:0045176 15 10 0,000 0,02137725 0,04571881 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02137725 0,04567821 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02137725 0,04563767 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02137725 0,04559722 ! midbrain development GO:0030901 13 10 0,000 0,02137725 0,04555683 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02137725 0,04551651 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02137725 0,04547627 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02137725 0,04543609 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02137725 0,04539599 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02137725 0,04535596 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02137725 0,045316 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02137725 0,04527611 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,02137725 0,04523629 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,02137725 0,04519654 ! oocyte development GO:0048599 17 10 0,000 0,02137725 0,04515686 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02137725 0,04511725 ! blastocyst formation GO:0001825 17 10 0,000 0,02137725 0,0450777 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02137725 0,04503823 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02137725 0,04499883 ! activation of innate immune response GO:0002218 12 10 0,000 0,02137725 0,04495949 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02137725 0,04492023 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02137725 0,04488103 ! response to nicotine GO:0035094 20 10 0,000 0,02137725 0,0448419 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02137725 0,04480284 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02137725 0,04476385 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02137725 0,04472492 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02349006 0,0491026 ! respiratory burst GO:0045730 17 11 0,000 0,02349006 0,04905997 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02349006 0,04901742 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02349006 0,04897495 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02349006 0,04893254 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02349006 0,04889022 ! thyroid gland development GO:0030878 26 11 0,000 0,02349006 0,04884796 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02349006 0,04880578 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02349006 0,04876367 ! response to pain GO:0048265 24 11 0,000 0,02349006 0,04872163 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02349006 0,04867966 ! T cell proliferation GO:0042098 26 11 0,000 0,02349006 0,04863777 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02349006 0,04859595 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02349006 0,0485542 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02349006 0,04851252 ! bone resorption GO:0045453 16 11 0,000 0,02349006 0,04847092 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02349006 0,04842938 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02349006 0,04838792 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02349006 0,04834653 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02349006 0,0483052 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02349006 0,04826395 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02349006 0,04822277 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02349006 0,04818166 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02349006 0,04814062 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02349006 0,04809965 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02349006 0,04805875 ! lipid digestion GO:0044241 18 11 0,000 0,02349006 0,04801792 ! UV protection GO:0009650 19 11 0,000 0,02349006 0,04797716 ! adult heart development GO:0007512 14 11 0,000 0,02349006 0,04793646 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02349006 0,04789584 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02349006 0,04785528 ! temperature homeostasis GO:0001659 17 11 0,000 0,02349006 0,0478148 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02349006 0,04777438 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02349006 0,04773403 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02349006 0,04769375 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02349006 0,04765353 ! regulation of organ growth GO:0046620 13 11 0,000 0,02349006 0,04761339 ! pigment granule localization GO:0051875 20 11 0,000 0,02349006 0,04757331 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02349006 0,0475333 ! vasoconstriction GO:0042310 18 11 0,000 0,02349006 0,04749335 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02349006 0,04745348 ! embryonic axis specification GO:0000578 18 11 0,000 0,02349006 0,04741367 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02349006 0,04737392 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02349006 0,04733425 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02349006 0,04729464 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02349006 0,04725509 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02349006 0,04721561 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02349006 0,0471762 ! zymogen activation GO:0031638 15 11 0,000 0,02349006 0,04713685 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02349006 0,04709757 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02349006 0,04705836 ! nucleosome positioning GO:0016584 15 11 0,000 0,02349006 0,04701921 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02349006 0,04698012 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02349006 0,0469411 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02349006 0,04690215 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02349006 0,04686326 ! acid secretion GO:0046717 18 11 0,000 0,02349006 0,04682443 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02349006 0,04678567 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02349006 0,04674697 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02349006 0,04670834 ! oocyte differentiation GO:0009994 18 11 0,000 0,02349006 0,04666977 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02349006 0,04663126 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02349006 0,04659282 ! cholesterol efflux GO:0033344 19 11 0,000 0,02349006 0,04655444 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02349006 0,04651612 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02349006 0,04647787 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02349006 0,04643968 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02349006 0,04640155 ! embryonic gut development GO:0048566 15 11 0,000 0,02349006 0,04636349 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02349006 0,04632548 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02349006 0,04628754 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02349006 0,04624966 ! defense response to fungus GO:0050832 13 11 0,000 0,02349006 0,04621185 ! developmental induction GO:0031128 19 11 0,000 0,02349006 0,04617409 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02349006 0,0461364 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02349006 0,04609877 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02349006 0,0460612 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02349006 0,04602369 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02349006 0,04598624 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02349006 0,04594885 ! nucleus localization GO:0051647 19 11 0,000 0,02349006 0,04591153 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02349006 0,04587426 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02559838 0,0499511 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02559838 0,04991063 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02559838 0,04987021 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02559838 0,04982986 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02559838 0,04978958 ! virus-host interaction GO:0019048 29 12 0,000 0,02559838 0,04974936 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02559838 0,04970921 ! cartilage condensation GO:0001502 20 12 0,000 0,02559838 0,04966912 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02559838 0,0496291 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02559838 0,04958914 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02559838 0,04954925 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02559838 0,04950941 ! hippocampus development GO:0021766 26 12 0,000 0,02559838 0,04946965 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,02559838 0,04942995 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02559838 0,04939031 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02559838 0,04935073 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02559838 0,04931122 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02559838 0,04927177 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02559838 0,04923238 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02559838 0,04919306 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02559838 0,0491538 ! drug transport GO:0015893 16 12 0,000 0,02559838 0,0491146 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02559838 0,04907547 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02559838 0,04903639 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02559838 0,04899738 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02559838 0,04895844 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02559838 0,04891955 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02559838 0,04888072 ! forebrain cell migration GO:0021885 21 12 0,000 0,02559838 0,04884196 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02559838 0,04880326 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02559838 0,04876462 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02559838 0,04872604 ! entry into host cell GO:0030260 32 12 0,000 0,02559838 0,04868752 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02559838 0,04864906 ! monoamine transport GO:0015844 18 12 0,000 0,02559838 0,04861066 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02559838 0,04857233 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02559838 0,04853405 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02559838 0,04849584 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02559838 0,04845768 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02559838 0,04841958 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02559838 0,04838155 ! protein homotetramerization GO:0051289 21 12 0,000 0,02559838 0,04834357 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02559838 0,04830566 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02559838 0,0482678 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02559838 0,04823 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02559838 0,04819226 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02559838 0,04815458 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02559838 0,04811696 ! fucose catabolic process GO:0019317 22 12 0,000 0,02559838 0,0480794 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02559838 0,0480419 ! histone methylation GO:0016571 26 12 0,000 0,02559838 0,04800445 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02559838 0,04796707 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02559838 0,04792974 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02559838 0,04789247 ! T cell homeostasis GO:0043029 25 12 0,000 0,02559838 0,04785525 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02559838 0,0478181 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02559838 0,047781 ! spleen development GO:0048536 22 12 0,000 0,02559838 0,04774396 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02559838 0,04770698 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02559838 0,04767006 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02559838 0,04763319 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02559838 0,04759638 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02559838 0,04755962 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02559838 0,04752293 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02559838 0,04748629 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02559838 0,0474497 ! response to cold GO:0009409 17 12 0,000 0,02559838 0,04741317 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02559838 0,0473767 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02559838 0,04734029 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02770222 0,05119167 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02770222 0,05115238 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02770222 0,05111315 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02770222 0,05107399 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02770222 0,05103488 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02770222 0,05099583 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02770222 0,05095684 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02770222 0,05091792 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02770222 0,05087905 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02770222 0,05084024 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02770222 0,05080149 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02770222 0,0507628 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02770222 0,05072416 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02770222 0,05068559 ! methionine metabolic process GO:0006555 27 13 0,000 0,02770222 0,05064708 ! plasma membrane organization GO:0007009 24 13 0,000 0,02770222 0,05060862 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02770222 0,05057022 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02770222 0,05053188 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02770222 0,0504936 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02770222 0,05045538 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02770222 0,05041721 ! response to X-ray GO:0010165 25 13 0,000 0,02770222 0,0503791 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02770222 0,05034105 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02770222 0,05030306 ! exocrine system development GO:0035272 32 13 0,000 0,02770222 0,05026512 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02770222 0,05022724 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02770222 0,05018942 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02770222 0,05015166 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02770222 0,05011395 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02770222 0,0500763 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02770222 0,0500387 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02770222 0,05000116 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02770222 0,04996368 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02770222 0,04992626 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02770222 0,04988889 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02770222 0,04985157 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02770222 0,04981431 ! ribosome assembly GO:0042255 17 13 0,000 0,02770222 0,04977711 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02770222 0,04973996 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02770222 0,04970287 ! chromatin silencing GO:0006342 26 13 0,000 0,02770222 0,04966584 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02770222 0,04962885 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02770222 0,04959193 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02770222 0,04955506 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02770222 0,04951824 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02770222 0,04948148 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02770222 0,04944477 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02770222 0,04940812 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02770222 0,04937152 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02770222 0,04933497 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02770222 0,04929848 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02770222 0,04926205 ! embryonic placenta development GO:0001892 23 13 0,000 0,02770222 0,04922567 ! insulin secretion GO:0030073 23 13 0,000 0,02770222 0,04918934 ! actin filament polymerization GO:0030041 24 13 0,000 0,02770222 0,04915306 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02770222 0,04911684 ! acrosome reaction GO:0007340 18 13 0,000 0,02770222 0,04908067 ! rRNA transcription GO:0009303 25 14 0,000 0,02980159 0,05276132 ! lactation GO:0007595 26 14 0,000 0,02980159 0,05272252 ! reproductive cellular process GO:0048610 20 14 0,000 0,02980159 0,05268378 ! tRNA modification GO:0006400 20 14 0,000 0,02980159 0,0526451 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02980159 0,05260648 ! regulation of S phase GO:0033261 23 14 0,000 0,02980159 0,05256791 ! water transport GO:0006833 21 14 0,000 0,02980159 0,0525294 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02980159 0,05249094 ! non-recombinational repair GO:0000726 25 14 0,000 0,02980159 0,05245255 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02980159 0,0524142 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02980159 0,05237592 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02980159 0,05233769 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02980159 0,05229951 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02980159 0,05226139 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02980159 0,05222333 ! palate development GO:0060021 31 14 0,000 0,02980159 0,05218532 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02980159 0,05214737 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02980159 0,05210947 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02980159 0,05207163 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02980159 0,05203384 ! arginine metabolic process GO:0006525 17 14 0,000 0,02980159 0,05199611 ! regulation of heart rate GO:0002027 24 14 0,000 0,02980159 0,05195843 ! organic alcohol transport GO:0015850 29 14 0,000 0,02980159 0,0519208 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02980159 0,05188323 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02980159 0,05184572 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02980159 0,05180826 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02980159 0,05177085 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02980159 0,0517335 ! L-amino acid transport GO:0015807 30 14 0,000 0,02980159 0,0516962 ! bone mineralization GO:0030282 17 14 0,000 0,02980159 0,05165895 ! stem cell development GO:0048864 43 14 0,000 0,02980159 0,05162176 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02980159 0,05158463 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02980159 0,05154754 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02980159 0,05151051 ! cerebellum development GO:0021549 21 14 0,000 0,02980159 0,05147353 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02980159 0,05143661 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02980159 0,05139973 ! response to gamma radiation GO:0010332 28 14 0,000 0,02980159 0,05136291 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02980159 0,05132615 ! cofactor transport GO:0051181 26 14 0,000 0,02980159 0,05128943 ! NADP metabolic process GO:0006739 24 14 0,000 0,02980159 0,05125277 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02980159 0,05121616 ! intestinal absorption GO:0050892 25 14 0,000 0,02980159 0,05117961 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02980159 0,0511431 ! oxygen transport GO:0015671 21 14 0,000 0,02980159 0,05110665 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02980159 0,05107025 ! male genitalia development GO:0030539 24 14 0,000 0,02980159 0,0510339 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02980159 0,0509976 ! regulation of axon extension GO:0030516 37 14 0,000 0,02980159 0,05096136 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02980159 0,05092516 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02980159 0,05088902 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0318965 0,05442764 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0318965 0,05438906 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0318965 0,05435054 ! superoxide anion generation GO:0042554 20 15 0,000 0,0318965 0,05431208 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0318965 0,05427367 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0318965 0,05423531 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0318965 0,05419701 ! copper ion transport GO:0006825 20 15 0,000 0,0318965 0,05415876 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0318965 0,05412057 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0318965 0,05408243 ! sulfate transport GO:0008272 23 15 0,000 0,0318965 0,05404434 ! response to cAMP GO:0051591 22 15 0,000 0,0318965 0,05400631 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0318965 0,05396833 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0318965 0,05393041 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0318965 0,05389253 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0318965 0,05385471 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0318965 0,05381695 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0318965 0,05377923 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0318965 0,05374157 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0318965 0,05370397 ! pituitary gland development GO:0021983 29 15 0,000 0,0318965 0,05366641 ! vesicle coating GO:0006901 33 15 0,000 0,0318965 0,05362891 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0318965 0,05359146 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0318965 0,05355406 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,0318965 0,05351671 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0318965 0,05347942 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,0318965 0,05344218 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,0318965 0,05340499 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0318965 0,05336785 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0318965 0,05333076 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0318965 0,05329373 ! histone deacetylation GO:0016575 20 15 0,000 0,0318965 0,05325674 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0318965 0,05321981 ! tissue regeneration GO:0042246 26 15 0,000 0,0318965 0,05318293 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0318965 0,0531461 ! water homeostasis GO:0030104 27 15 0,000 0,0318965 0,05310932 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0318965 0,05307259 ! muscle maintenance GO:0046716 26 15 0,000 0,0318965 0,05303591 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0318965 0,05299929 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0318965 0,05296271 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0318965 0,05292618 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0318965 0,05288971 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0318965 0,05285328 ! cell killing GO:0001906 29 15 0,000 0,0318965 0,05281691 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0318965 0,05278058 ! detection of bacterium GO:0016045 18 15 0,000 0,0318965 0,05274431 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,0318965 0,05270808 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0318965 0,05267191 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0318965 0,05263578 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0318965 0,0525997 ! peptide hormone processing GO:0016486 23 15 0,000 0,0318965 0,05256368 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03398695 0,05597029 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03398695 0,055932 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03398695 0,05589377 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03398695 0,05585559 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03398695 0,05581747 ! bone remodeling GO:0046849 27 16 0,000 0,03398695 0,05577939 ! filopodium assembly GO:0046847 32 16 0,000 0,03398695 0,05574137 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03398695 0,0557034 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03398695 0,05566548 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03398695 0,05562761 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03398695 0,0555898 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03398695 0,05555203 ! startle response GO:0001964 28 16 0,000 0,03398695 0,05551432 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03398695 0,05547666 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03398695 0,05543904 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03398695 0,05540148 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03398695 0,05536397 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03398695 0,05532652 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03398695 0,05528911 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03398695 0,05525175 ! response to osmotic stress GO:0006970 25 16 0,000 0,03398695 0,05521444 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03398695 0,05517719 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03398695 0,05513998 ! fructose metabolic process GO:0006000 25 16 0,000 0,03398695 0,05510282 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03398695 0,05506572 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03398695 0,05502866 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03398695 0,05499166 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03398695 0,0549547 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03398695 0,05491779 ! axon cargo transport GO:0008088 43 16 0,000 0,03398695 0,05488093 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03398695 0,05484413 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03398695 0,05480737 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,03398695 0,05477066 ! DNA replication initiation GO:0006270 27 16 0,000 0,03398695 0,054734 ! neuron recognition GO:0008038 35 16 0,000 0,03398695 0,05469739 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03398695 0,05466082 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03398695 0,05462431 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03398695 0,05458784 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03398695 0,05455143 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03398695 0,05451506 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03398695 0,05447874 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03398695 0,05444247 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03398695 0,05440625 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03398695 0,05437007 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03398695 0,05433395 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03398695 0,05429787 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03398695 0,05426184 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03398695 0,05422586 ! defense response to virus GO:0051607 37 16 0,000 0,03398695 0,05418992 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03607295 0,05747783 ! metencephalon development GO:0022037 30 17 0,000 0,03607295 0,05743979 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03607295 0,0574018 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03607295 0,05736386 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03607295 0,05732597 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03607295 0,05728813 ! signal complex assembly GO:0007172 41 17 0,000 0,03607295 0,05725034 ! endothelial cell migration GO:0043542 28 17 0,000 0,03607295 0,0572126 ! inositol metabolic process GO:0006020 28 17 0,000 0,03607295 0,05717491 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03607295 0,05713727 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03607295 0,05709968 ! glial cell development GO:0021782 27 17 0,000 0,03607295 0,05706214 ! limbic system development GO:0021761 36 17 0,000 0,03607295 0,05702465 ! adult walking behavior GO:0007628 33 17 0,000 0,03607295 0,05698721 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03607295 0,05694982 ! heart looping GO:0001947 30 17 0,000 0,03607295 0,05691247 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03607295 0,05687518 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03607295 0,05683793 ! myoblast differentiation GO:0045445 45 17 0,000 0,03607295 0,05680073 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03607295 0,05676358 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,03607295 0,05672648 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03607295 0,05668943 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03607295 0,05665243 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03607295 0,05661547 ! glycine metabolic process GO:0006544 28 17 0,000 0,03607295 0,05657857 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03607295 0,05654171 ! NAD metabolic process GO:0019674 29 17 0,000 0,03607295 0,0565049 ! membrane budding GO:0006900 37 17 0,000 0,03607295 0,05646813 ! DNA integration GO:0015074 29 17 0,000 0,03607295 0,05643142 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03607295 0,05639475 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03607295 0,05635813 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03607295 0,05632156 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03607295 0,05628503 ! genitalia development GO:0048806 30 17 0,000 0,03607295 0,05624855 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03607295 0,05621212 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03607295 0,05617574 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03607295 0,0561394 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03607295 0,05610312 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03607295 0,05606687 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03607295 0,05603068 ! steroid catabolic process GO:0006706 31 17 0,000 0,03607295 0,05599453 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03607295 0,05595843 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03607295 0,05592237 ! gas transport GO:0015669 25 17 0,000 0,03607295 0,05588636 ! organic cation transport GO:0015695 31 17 0,000 0,03607295 0,0558504 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03607295 0,05581448 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03607295 0,05577861 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03607295 0,05574279 ! microspike assembly GO:0030035 36 17 0,000 0,03607295 0,05570701 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03607295 0,05567128 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03607295 0,05563559 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03815452 0,05880831 ! neuron maturation GO:0042551 42 18 0,000 0,03815452 0,05877066 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03815452 0,05873306 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03815452 0,05869551 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03815452 0,058658 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03815452 0,05862055 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03815452 0,05858314 ! memory GO:0007613 31 18 0,000 0,03815452 0,05854578 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03815452 0,05850846 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03815452 0,0584712 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03815452 0,05843398 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03815452 0,05839681 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03815452 0,05835968 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03815452 0,0583226 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03815452 0,05828557 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03815452 0,05824859 ! response to retinoic acid GO:0032526 26 18 0,000 0,03815452 0,05821165 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03815452 0,05817476 ! response to fungus GO:0009620 21 18 0,000 0,03815452 0,05813792 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03815452 0,05810113 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03815452 0,05806438 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03815452 0,05802767 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03815452 0,05799102 ! vitamin transport GO:0051180 27 18 0,000 0,03815452 0,05795441 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03815452 0,05791784 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03815452 0,05788132 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03815452 0,05784485 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03815452 0,05780842 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03815452 0,05777204 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03815452 0,05773571 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03815452 0,05769942 ! protein secretion GO:0009306 39 19 0,000 0,04023166 0,06080238 ! positive regulation of translation GO:0045727 30 19 0,000 0,04023166 0,06076421 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04023166 0,06072609 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04023166 0,06068802 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04023166 0,06064999 ! skin development GO:0043588 36 19 0,000 0,04023166 0,06061201 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04023166 0,06057408 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04023166 0,0605362 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04023166 0,06049837 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04023166 0,06046058 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04023166 0,06042284 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04023166 0,06038514 ! cerebral cortex development GO:0021987 36 19 0,000 0,04023166 0,0603475 ! pigmentation during development GO:0048066 41 19 0,000 0,04023166 0,0603099 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04023166 0,06027234 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04023166 0,06023484 ! heme metabolic process GO:0042168 36 19 0,000 0,04023166 0,06019738 ! neuromuscular junction development GO:0007528 34 19 0,000 0,04023166 0,06015997 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04023166 0,0601226 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04023166 0,06008528 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04023166 0,06004801 ! peptide cross-linking GO:0018149 37 19 0,000 0,04023166 0,06001078 ! protein export from nucleus GO:0006611 36 19 0,000 0,04023166 0,0599736 ! heart process GO:0003015 30 19 0,000 0,04023166 0,05993646 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04023166 0,05989937 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,04023166 0,05986233 ! cellular pigmentation GO:0033059 36 19 0,000 0,04023166 0,05982533 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04023166 0,05978838 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04023166 0,05975147 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04023166 0,05971461 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04023166 0,0596778 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04023166 0,05964103 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04023166 0,0596043 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04023166 0,05956762 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04023166 0,05953099 ! cilium assembly GO:0042384 37 19 0,000 0,04023166 0,0594944 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04023166 0,05945785 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04230439 0,06248273 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,04230439 0,0624444 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04230439 0,06240611 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04230439 0,06236787 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04230439 0,06232968 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,04230439 0,06229153 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04230439 0,06225344 ! response to vitamin GO:0033273 31 20 0,000 0,04230439 0,06221538 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04230439 0,06217738 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,04230439 0,06213942 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04230439 0,06210151 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04230439 0,06206364 ! response to alkaloid GO:0043279 38 20 0,000 0,04230439 0,06202582 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04230439 0,06198804 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,04230439 0,06195031 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04230439 0,06191263 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04230439 0,061875 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04230439 0,0618374 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04230439 0,06179986 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04230439 0,06176236 ! body fluid secretion GO:0007589 31 20 0,000 0,04230439 0,0617249 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04230439 0,0616875 ! peptide secretion GO:0002790 35 20 0,000 0,04230439 0,06165013 ! stem cell differentiation GO:0048863 53 20 0,000 0,04230439 0,06161281 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04230439 0,06157554 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04230439 0,06153831 ! sensory perception of pain GO:0019233 30 20 0,000 0,04230439 0,06150113 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04230439 0,06146399 ! diencephalon development GO:0021536 34 20 0,000 0,04230439 0,0614269 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04230439 0,06138985 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04230439 0,06135284 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,04230439 0,06131588 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04230439 0,06127897 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04230439 0,0612421 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04230439 0,06120527 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04230439 0,06116849 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04230439 0,06113175 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04230439 0,06109506 ! regulation of glucose import GO:0046324 29 20 0,000 0,04230439 0,06105841 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04230439 0,0610218 ! actin filament-based movement GO:0030048 43 20 0,000 0,04230439 0,06098524 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,04230439 0,06094872 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04230439 0,06091225 ! negative regulation of translation GO:0017148 29 20 0,000 0,04230439 0,06087582 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04230439 0,06083943 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,04230439 0,06080309 ! regulation of cell killing GO:0031341 42 21 0,000 0,04437271 0,06373776 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04437271 0,06369973 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04437271 0,06366174 ! hormone secretion GO:0046879 38 21 0,000 0,04437271 0,0636238 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04437271 0,06358591 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04437271 0,06354806 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04437271 0,06351026 ! axis specification GO:0009798 38 21 0,000 0,04437271 0,0634725 ! ovarian follicle development GO:0001541 35 21 0,000 0,04437271 0,06343479 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04437271 0,06339712 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04437271 0,06335949 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04437271 0,06332191 ! cell aging GO:0007569 44 21 0,000 0,04437271 0,06328438 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04437271 0,06324689 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04437271 0,06320944 ! cytolysis GO:0019835 24 21 0,000 0,04437271 0,06317204 ! vasodilation GO:0042311 39 21 0,000 0,04437271 0,06313468 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04437271 0,06309737 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04437271 0,0630601 ! oogenesis GO:0048477 36 21 0,000 0,04437271 0,06302287 ! DNA modification GO:0006304 34 21 0,000 0,04437271 0,06298569 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04437271 0,06294855 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04437271 0,06291146 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04437271 0,06287441 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,04437271 0,0628374 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04437271 0,06280044 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04437271 0,06276352 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04437271 0,06272664 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04437271 0,06268981 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04437271 0,06265302 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04437271 0,06261627 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04437271 0,06257957 ! collagen catabolic process GO:0030574 28 21 0,000 0,04437271 0,06254291 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04437271 0,06250629 ! gut development GO:0048565 39 21 0,000 0,04437271 0,06246972 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04643663 0,06533716 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04643663 0,06529897 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04643663 0,06526083 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04643663 0,06522273 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04643663 0,06518468 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04643663 0,06514667 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04643663 0,06510871 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04643663 0,06507079 ! regeneration GO:0031099 41 22 0,000 0,04643663 0,06503291 ! keratinization GO:0031424 28 22 0,000 0,04643663 0,06499508 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04643663 0,06495729 ! sensory perception of taste GO:0050909 28 22 0,000 0,04643663 0,06491955 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04643663 0,06488185 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04643663 0,06484419 ! vacuolar transport GO:0007034 36 22 0,000 0,04643663 0,06480658 ! lysosome organization GO:0007040 41 22 0,000 0,04643663 0,06476901 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04643663 0,06473148 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04643663 0,064694 ! fucose metabolic process GO:0006004 39 22 0,000 0,04643663 0,06465656 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04643663 0,06461917 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04643663 0,06458181 ! ureteric bud development GO:0001657 43 22 0,000 0,04643663 0,06454451 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04643663 0,06450724 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04643663 0,06447002 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04643663 0,06443284 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,04643663 0,0643957 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04643663 0,06435861 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04643663 0,06432155 ! sarcomere organization GO:0045214 30 22 0,000 0,04643663 0,06428454 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04643663 0,06424758 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04643663 0,06421065 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04643663 0,06417377 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04643663 0,06413693 ! protein stabilization GO:0050821 39 22 0,000 0,04643663 0,06410014 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04849617 0,06690469 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04849617 0,06686635 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04849617 0,06682805 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04849617 0,0667898 ! gluconeogenesis GO:0006094 33 23 0,000 0,04849617 0,06675159 ! viral genome replication GO:0019079 41 23 0,000 0,04849617 0,06671342 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04849617 0,0666753 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04849617 0,06663722 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04849617 0,06659919 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04849617 0,06656119 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,04849617 0,06652325 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04849617 0,06648534 ! visual behavior GO:0007632 42 23 0,000 0,04849617 0,06644748 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04849617 0,06640966 ! response to ethanol GO:0045471 46 23 0,000 0,04849617 0,06637188 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04849617 0,06633415 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04849617 0,06629646 ! peroxisome organization GO:0007031 37 23 0,000 0,04849617 0,06625881 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04849617 0,06622121 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04849617 0,06618365 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04849617 0,06614613 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04849617 0,06610865 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,04849617 0,06607122 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04849617 0,06603383 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04849617 0,06599648 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04849617 0,06595917 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04849617 0,06592191 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04849617 0,06588468 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04849617 0,0658475 ! fatty acid transport GO:0015908 44 23 0,000 0,04849617 0,06581036 ! platelet activation GO:0030168 37 23 0,000 0,04849617 0,06577327 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04849617 0,06573621 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04849617 0,0656992 ! hormone transport GO:0009914 40 23 0,000 0,04849617 0,06566222 ! cell-cell recognition GO:0009988 25 23 0,000 0,04849617 0,06562529 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04849617 0,06558841 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04849617 0,06555156 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04849617 0,06551475 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04849617 0,06547799 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04849617 0,06544126 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,05055132 0,06817627 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,05055132 0,06813808 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,05055132 0,06809993 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,05055132 0,06806182 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,05055132 0,06802375 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,05055132 0,06798573 ! spinal cord development GO:0021510 47 24 0,000 0,05055132 0,06794775 ! vacuole organization GO:0007033 43 24 0,000 0,05055132 0,06790981 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,05055132 0,06787191 ! digestive system process GO:0022600 39 24 0,000 0,05055132 0,06783406 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,05055132 0,06779625 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,05055132 0,06775848 ! regulation of behavior GO:0050795 43 24 0,000 0,05055132 0,06772075 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,05055132 0,06768307 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,05055132 0,06764542 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,05055132 0,06760782 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,05055132 0,06757026 ! pallium development GO:0021543 49 24 0,000 0,05055132 0,06753274 ! pentose metabolic process GO:0019321 35 24 0,000 0,05055132 0,06749527 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,05055132 0,06745783 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,05055132 0,06742044 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,05055132 0,06738309 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,05055132 0,06734577 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,05055132 0,06730851 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,05055132 0,06727128 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,05055132 0,06723409 ! regulation of amine transport GO:0051952 40 24 0,000 0,05055132 0,06719694 ! protein tetramerization GO:0051262 52 24 0,000 0,05055132 0,06715984 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,0526021 0,06984583 ! myelination GO:0042552 45 25 0,000 0,0526021 0,06980731 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,0526021 0,06976883 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,0526021 0,06973039 ! phototransduction GO:0007602 33 25 0,000 0,0526021 0,06969199 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,0526021 0,06965363 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,0526021 0,06961532 ! sperm motility GO:0030317 31 25 0,000 0,0526021 0,06957705 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,0526021 0,06953882 ! receptor metabolic process GO:0043112 46 25 0,000 0,0526021 0,06950063 ! chromosome condensation GO:0030261 45 25 0,000 0,0526021 0,06946249 ! osteoblast differentiation GO:0001649 60 25 0,000 0,0526021 0,06942438 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,0526021 0,06938632 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,0526021 0,0693483 ! negative regulation of cell development GO:0010721 73 25 0,000 0,0526021 0,06931032 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,0526021 0,06927239 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,0526021 0,06923449 ! interaction with host GO:0051701 62 25 0,000 0,0526021 0,06919664 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,0526021 0,06915882 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,0526021 0,06912105 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,0526021 0,06908332 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,0526021 0,06904564 ! immunoglobulin production GO:0002377 55 25 0,000 0,0526021 0,06900799 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,0526021 0,06897038 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,0526021 0,06893282 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,0526021 0,06889529 ! telomere organization GO:0032200 43 25 0,000 0,0526021 0,06885781 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,0526021 0,06882036 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,0526021 0,06878296 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05464852 0,07142006 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05464852 0,07138129 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05464852 0,07134256 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05464852 0,07130387 ! initiation of viral infection GO:0019059 57 26 0,000 0,05464852 0,07126522 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05464852 0,07122662 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05464852 0,07118805 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05464852 0,07114953 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05464852 0,07111105 ! molting cycle process GO:0022404 50 26 0,000 0,05464852 0,07107261 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05464852 0,07103422 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,05464852 0,07099586 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05464852 0,07095755 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05464852 0,07091927 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,05464852 0,07088104 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05464852 0,07084285 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05464852 0,0708047 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,05464852 0,0707666 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05464852 0,07072853 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05464852 0,0706905 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05464852 0,07065252 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05464852 0,07061457 ! blastocyst development GO:0001824 49 26 0,000 0,05464852 0,07057667 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05464852 0,07053881 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05464852 0,07050098 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05464852 0,0704632 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,05669059 0,07305707 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,05669059 0,07301796 ! iron ion transport GO:0006826 59 27 0,000 0,05669059 0,07297889 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,05669059 0,07293987 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,05669059 0,07290088 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,05669059 0,07286194 ! fat cell differentiation GO:0045444 50 27 0,000 0,05669059 0,07282304 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,05669059 0,07278418 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,05669059 0,07274536 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,05669059 0,07270658 ! autophagy GO:0006914 41 27 0,000 0,05669059 0,07266785 ! male gonad development GO:0008584 44 27 0,000 0,05669059 0,07262915 ! response to toxin GO:0009636 47 27 0,000 0,05669059 0,0725905 ! primary neural tube formation GO:0014020 51 27 0,000 0,05669059 0,07255189 ! base-excision repair GO:0006284 41 27 0,000 0,05669059 0,07251332 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,05669059 0,07247479 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,05669059 0,0724363 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,05669059 0,07239785 ! glutathione metabolic process GO:0006749 39 27 0,000 0,05669059 0,07235944 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,05669059 0,07232108 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,05669059 0,07228275 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,05669059 0,07224446 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05872831 0,07480165 ! circadian rhythm GO:0007623 50 28 0,000 0,05872831 0,07476207 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05872831 0,07472253 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05872831 0,07468304 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05872831 0,07464359 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05872831 0,07460418 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05872831 0,07456481 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05872831 0,07452548 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05872831 0,0744862 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05872831 0,07444695 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05872831 0,07440775 ! synaptogenesis GO:0007416 42 28 0,000 0,05872831 0,07436859 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05872831 0,07432946 ! lipid oxidation GO:0034440 43 28 0,000 0,05872831 0,07429039 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05872831 0,07425135 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05872831 0,07421235 ! translational initiation GO:0006413 65 29 0,000 0,0607617 0,07674155 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0607617 0,07670128 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0607617 0,07666106 ! regulation of pH GO:0006885 43 29 0,000 0,0607617 0,07662088 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0607617 0,07658075 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0607617 0,07654065 ! catechol metabolic process GO:0009712 54 29 0,000 0,0607617 0,0765006 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0607617 0,07646059 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0607617 0,07642062 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0607617 0,07638069 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0607617 0,07634081 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0607617 0,07630096 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0607617 0,07626116 ! cell fate determination GO:0001709 60 29 0,000 0,0607617 0,0762214 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0607617 0,07618168 ! detection of light stimulus GO:0009583 38 29 0,000 0,0607617 0,076142 ! tissue homeostasis GO:0001894 48 29 0,000 0,0607617 0,07610237 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,06279076 0,0786028 ! zinc ion transport GO:0006829 45 30 0,000 0,06279076 0,07856192 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,06279076 0,07852109 ! regulation of innate immune response GO:0045088 51 30 0,000 0,06279076 0,0784803 ! acute-phase response GO:0006953 49 30 0,000 0,06279076 0,07843955 ! myofibril assembly GO:0030239 47 30 0,000 0,06279076 0,07839885 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,06279076 0,07835818 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,06279076 0,07831756 ! phospholipid transport GO:0015914 51 30 0,000 0,06279076 0,07827698 ! ensheathment of neurons GO:0007272 57 30 0,000 0,06279076 0,07823645 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,06279076 0,07819595 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,06279076 0,0781555 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,06279076 0,07811509 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,06279076 0,07807472 ! eye morphogenesis GO:0048592 60 30 0,000 0,06279076 0,07803439 ! response to heat GO:0009408 50 30 0,000 0,06279076 0,0779941 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06481551 0,08046755 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06481551 0,08042606 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06481551 0,0803846 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06481551 0,08034318 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06481551 0,08030181 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,06481551 0,08026048 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06481551 0,0802192 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06481551 0,08017795 ! ovulation cycle process GO:0022602 49 31 0,000 0,06481551 0,08013675 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,06481551 0,08009559 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06481551 0,08005448 ! peptide transport GO:0015833 55 31 0,000 0,06481551 0,0800134 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06481551 0,07997237 ! mesoderm formation GO:0001707 69 31 0,000 0,06481551 0,07993138 ! natural killer cell activation GO:0030101 45 31 0,000 0,06481551 0,07989043 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06481551 0,07984952 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06481551 0,07980866 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06481551 0,07976784 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06481551 0,07972706 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06481551 0,07968632 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06683595 0,08212835 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06683595 0,08208642 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06683595 0,08204454 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06683595 0,0820027 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06683595 0,08196091 ! spliceosome assembly GO:0000245 67 32 0,000 0,06683595 0,08191916 ! spindle organization GO:0007051 46 32 0,000 0,06683595 0,08187745 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06683595 0,08183578 ! metanephros development GO:0001656 74 32 0,000 0,06683595 0,08179415 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06683595 0,08175257 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06683595 0,08171103 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06683595 0,08166953 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06683595 0,08162807 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,06683595 0,08158666 ! muscle cell development GO:0055001 49 32 0,000 0,06683595 0,08154529 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06683595 0,08150395 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06683595 0,08146267 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06683595 0,08142142 ! ovulation cycle GO:0042698 51 32 0,000 0,06683595 0,08138021 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06683595 0,08133905 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06683595 0,08129793 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06683595 0,08125685 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06683595 0,08121581 ! gene silencing GO:0016458 65 32 0,000 0,06683595 0,08117481 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,0688521 0,0835813 ! post-embryonic development GO:0009791 69 33 0,000 0,0688521 0,08353915 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,0688521 0,08349705 ! protein targeting to membrane GO:0006612 68 33 0,000 0,0688521 0,08345498 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,0688521 0,08341296 ! ceramide metabolic process GO:0006672 64 33 0,000 0,0688521 0,08337098 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,0688521 0,08332905 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,0688521 0,08328715 ! adult locomotory behavior GO:0008344 59 33 0,000 0,0688521 0,0832453 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,0688521 0,08320349 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,0688521 0,08316172 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,07086395 0,08554875 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,07086395 0,08550585 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,07086395 0,08546299 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,07086395 0,08542017 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,07086395 0,0853774 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,07086395 0,08533467 ! mismatch repair GO:0006298 46 34 0,000 0,07086395 0,08529198 ! spermatid development GO:0007286 63 34 0,000 0,07086395 0,08524933 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,07086395 0,08520673 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,07086395 0,08516417 ! placenta development GO:0001890 53 34 0,000 0,07086395 0,08512165 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,07086395 0,08507917 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,07287152 0,08744583 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,07287152 0,08740224 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,07287152 0,08735869 ! odontogenesis GO:0042476 66 35 0,000 0,07287152 0,08731518 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,07287152 0,08727172 ! female gonad development GO:0008585 58 35 0,000 0,07287152 0,0872283 ! telencephalon development GO:0021537 68 35 0,000 0,07287152 0,08718493 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,07287152 0,08714159 ! cytokine production GO:0001816 59 35 0,000 0,07287152 0,0870983 ! neural tube formation GO:0001841 67 35 0,000 0,07287152 0,08705506 ! vesicle localization GO:0051648 64 35 0,000 0,07287152 0,08701185 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07487483 0,08935954 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07487483 0,08931524 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07487483 0,08927098 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07487483 0,08922676 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07487483 0,08918259 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07487483 0,08913846 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07487483 0,08909438 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07487483 0,08905034 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07487483 0,08900634 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,07487483 0,08896239 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07487483 0,08891848 ! aerobic respiration GO:0009060 55 36 0,000 0,07487483 0,08887461 ! embryonic organ development GO:0048568 57 36 0,000 0,07487483 0,08883079 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07487483 0,088787 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07487483 0,08874327 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07687387 0,09106771 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07687387 0,0910229 ! meiosis I GO:0007127 65 37 0,000 0,07687387 0,09097812 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07687387 0,09093339 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07687387 0,09088871 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07687387 0,09084407 ! organic anion transport GO:0015711 68 37 0,000 0,07687387 0,09079947 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07687387 0,09075492 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07687387 0,09071041 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07687387 0,09066594 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07687387 0,09062152 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07687387 0,09057714 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07687387 0,09053281 ! pigment metabolic process GO:0042440 80 37 0,000 0,07687387 0,09048851 ! spermatid differentiation GO:0048515 66 37 0,000 0,07687387 0,09044427 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,07886865 0,09274584 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,07886865 0,09270053 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07886865 0,09265526 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07886865 0,09261004 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07886865 0,09256487 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07886865 0,09251974 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07886865 0,09247465 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07886865 0,09242961 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07886865 0,09238461 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07886865 0,09233965 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07886865 0,09229474 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07886865 0,09224987 ! glucan metabolic process GO:0044042 62 38 0,000 0,07886865 0,09220504 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,0808592 0,09448627 ! learning GO:0007612 77 39 0,000 0,0808592 0,0944404 ! ear morphogenesis GO:0042471 60 39 0,000 0,0808592 0,09439458 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,0808592 0,0943488 ! segmentation GO:0035282 67 39 0,000 0,0808592 0,09430307 ! ion transmembrane transport GO:0034220 66 39 0,000 0,0808592 0,09425738 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,0808592 0,09421173 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,0808592 0,09416613 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,0808592 0,09412057 ! RNA modification GO:0009451 57 39 0,000 0,0808592 0,09407506 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,0808592 0,09402959 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,0828455 0,09629289 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,0828455 0,09624639 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,0828455 0,09619994 ! feeding behavior GO:0007631 59 40 0,000 0,0828455 0,09615354 ! negative regulation of binding GO:0051100 72 40 0,000 0,0828455 0,09610718 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,0828455 0,09606086 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,0828455 0,09601459 ! maintenance of protein location GO:0045185 91 40 0,000 0,0828455 0,09596836 ! cytokinesis GO:0000910 72 40 0,000 0,0828455 0,09592218 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,08482758 0,09816987 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,08482758 0,09812268 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,08482758 0,09807553 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,08482758 0,09802842 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,08482758 0,09798136 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,08482758 0,09793434 ! T cell differentiation GO:0030217 81 41 0,000 0,08482758 0,09788737 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,08482758 0,09784045 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,08482758 0,09779356 ! female gamete generation GO:0007292 61 41 0,000 0,08482758 0,09774673 ! polyol metabolic process GO:0019751 66 41 0,000 0,08482758 0,09769994 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08680545 0,0999301 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08680545 0,09988231 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08680545 0,09983456 ! regulation of tube size GO:0035150 71 42 0,000 0,08680545 0,09978686 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08680545 0,09973921 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08680545 0,0996916 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08680545 0,09964404 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,08680545 0,09959652 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08680545 0,09954905 ! neuron migration GO:0001764 79 42 0,000 0,08680545 0,09950162 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08680545 0,09945424 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,0887791 0,10166707 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,0887791 0,10161871 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,0887791 0,10157038 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,0887791 0,10152211 ! glucose transport GO:0015758 65 43 0,000 0,0887791 0,10147388 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,0887791 0,1014257 ! striated muscle contraction GO:0006941 77 43 0,000 0,0887791 0,10137756 ! phagocytosis GO:0006909 90 43 0,000 0,0887791 0,10132947 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,0887791 0,10128142 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,09074856 0,10347916 ! hexose transport GO:0008645 67 44 0,000 0,09074856 0,10343014 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,09074856 0,10338117 ! male sex differentiation GO:0046661 76 44 0,000 0,09074856 0,10333224 ! double-strand break repair GO:0006302 81 44 0,000 0,09074856 0,10328336 ! biopolymer methylation GO:0043414 84 44 0,000 0,09074856 0,10323453 ! B cell differentiation GO:0030183 107 44 0,000 0,09074856 0,10318574 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,09074856 0,103137 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,09074856 0,1030883 ! developmental growth GO:0048589 82 44 0,000 0,09074856 0,10303965 ! maintenance of location in cell GO:0051651 97 44 0,000 0,09074856 0,10299105 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,09271382 0,10517183 ! glycolysis GO:0006096 65 45 0,000 0,09271382 0,10512227 ! leukocyte migration GO:0050900 68 45 0,000 0,09271382 0,10507275 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,09271382 0,10502328 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,09271382 0,10497386 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,09271382 0,10492448 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,09271382 0,10487515 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,09271382 0,10482587 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,09271382 0,10477663 ! cell growth GO:0016049 84 45 0,000 0,09271382 0,10472744 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,0946749 0,10689245 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,0946749 0,10684231 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,0946749 0,10679222 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,0946749 0,10674218 ! pigmentation GO:0043473 100 46 0,000 0,0946749 0,10669218 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,0946749 0,10664223 ! positive regulation of defense response GO:0031349 76 47 0,000 0,09663181 0,10879557 ! response to calcium ion GO:0051592 81 47 0,000 0,09663181 0,10874468 ! endosome transport GO:0016197 108 47 0,000 0,09663181 0,10869384 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,09663181 0,10864305 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,09663181 0,1085923 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,09663181 0,10854161 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,09663181 0,10849096 ! JNK cascade GO:0007254 91 47 0,000 0,09663181 0,10844036 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,09663181 0,1083898 ! methylation GO:0032259 90 47 0,000 0,09663181 0,10833929 ! mitochondrial transport GO:0006839 82 48 0,000 0,09858455 0,11047714 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,09858455 0,11042571 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,09858455 0,11037432 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,09858455 0,11032299 ! activation of caspase activity GO:0006919 84 48 0,000 0,09858455 0,1102717 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,09858455 0,11022045 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,09858455 0,11016926 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,09858455 0,11011811 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,10053313 0,11224256 ! regulation of action potential GO:0001508 95 49 0,000 0,10053313 0,1121905 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,10053313 0,11213849 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,10053313 0,11208652 ! regulation of ion transport GO:0043269 77 49 0,000 0,10053313 0,11203461 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,10053313 0,11198274 ! peptide metabolic process GO:0006518 76 49 0,000 0,10053313 0,11193092 ! response to temperature stimulus GO:0009266 76 49 0,000 0,10053313 0,11187915 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,10053313 0,11182742 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,10053313 0,11177575 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,10053313 0,11172412 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,10053313 0,11167254 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,10053313 0,111621 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,10247757 0,11372741 ! neuromuscular process GO:0050905 99 50 0,000 0,10247757 0,11367498 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,10247757 0,11362259 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,10247757 0,11357026 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,10247757 0,11351797 ! positive regulation of binding GO:0051099 78 51 0,000 0,10441787 0,11561408 ! viral infectious cycle GO:0019058 99 51 0,000 0,10441787 0,1155609 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,10441787 0,11550777 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,10441787 0,11545468 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,10441787 0,11540165 ! excretion GO:0007588 83 51 0,000 0,10441787 0,11534866 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,10441787 0,11529573 ! chromatin remodeling GO:0006338 109 51 0,000 0,10441787 0,11524284 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,10441787 0,11519 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,10441787 0,11513721 ! regulation of cell shape GO:0008360 125 51 0,000 0,10441787 0,11508447 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,10441787 0,11503177 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,10635404 0,11711113 ! positive regulation of growth GO:0045927 90 52 0,000 0,10635404 0,11705755 ! amino acid activation GO:0043038 92 52 0,000 0,10635404 0,11700403 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,10635404 0,11695055 ! synapse organization GO:0050808 85 52 0,000 0,10635404 0,11689713 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10828608 0,11896635 ! RNA catabolic process GO:0006401 93 53 0,000 0,10828608 0,11891206 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10828608 0,11885781 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,10828608 0,11880361 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10828608 0,11874946 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,10828608 0,11869536 ! cell maturation GO:0048469 100 53 0,000 0,10828608 0,11864131 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,11021402 0,12069865 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,11021402 0,12064373 ! cell recognition GO:0008037 85 54 0,000 0,11021402 0,12058887 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,11021402 0,12053406 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,11021402 0,12047929 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,11021402 0,12042458 ! chloride transport GO:0006821 90 55 0,000 0,11213785 0,12247102 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,11213785 0,12241545 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,11213785 0,12235994 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,11213785 0,12230447 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,11213785 0,12224905 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,11213785 0,12219369 ! aging GO:0007568 103 55 0,000 0,11213785 0,12213837 ! heart morphogenesis GO:0003007 97 55 0,000 0,11213785 0,1220831 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,11213785 0,12202789 ! RNA elongation GO:0006354 79 55 0,000 0,11213785 0,12197272 ! nuclear export GO:0051168 97 55 0,000 0,11213785 0,1219176 ! regulation of actin filament length GO:0030832 105 56 0,000 0,11405758 0,12394875 ! sensory perception of smell GO:0007608 80 56 0,000 0,11405758 0,12389279 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,11405758 0,12383689 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,11405758 0,12378103 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,11405758 0,12372522 ! regulation of DNA replication GO:0006275 101 56 0,000 0,11405758 0,12366946 ! proton transport GO:0015992 94 56 0,000 0,11405758 0,12361376 ! muscle fiber development GO:0048747 112 57 0,000 0,11597323 0,12563331 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,11597323 0,12557677 ! maintenance of location GO:0051235 118 57 0,000 0,11597323 0,12552028 ! hydrogen transport GO:0006818 97 58 0,000 0,1178848 0,12753184 ! adult behavior GO:0030534 99 58 0,000 0,1178848 0,12747452 ! positive regulation of secretion GO:0051047 95 59 0,000 0,11979229 0,129479 ! regulation of cellular component size GO:0032535 109 59 0,000 0,11979229 0,12942086 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,11979229 0,12936277 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,11979229 0,12930474 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,11979229 0,12924675 ! DNA catabolic process GO:0006308 86 59 0,000 0,11979229 0,12918882 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,11979229 0,12913094 ! establishment of organelle localization GO:0051656 109 59 0,000 0,11979229 0,12907311 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,12169573 0,13106532 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,12169573 0,13100668 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,12169573 0,13094809 ! regulation of heart contraction GO:0008016 110 60 0,000 0,12169573 0,13088955 ! camera-type eye development GO:0043010 116 60 0,000 0,12169573 0,13083107 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,12169573 0,13077263 ! kidney development GO:0001822 122 60 0,000 0,12169573 0,13071425 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,12359511 0,13269516 ! mesoderm development GO:0007498 119 61 0,000 0,12359511 0,13263597 ! tRNA processing GO:0008033 89 61 0,000 0,12359511 0,13257684 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,12359511 0,13251776 ! viral reproductive process GO:0022415 126 62 0,000 0,12549045 0,13448999 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,12549045 0,13443011 ! gonad development GO:0008406 98 62 0,000 0,12549045 0,13437028 ! regulation of mitosis GO:0007088 105 63 0,000 0,12738176 0,13633474 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,12738176 0,13627412 ! detection of external stimulus GO:0009581 91 63 0,000 0,12738176 0,13621356 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12738176 0,13615305 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,12926903 0,13810892 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,12926903 0,13804762 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,12926903 0,13798638 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,12926903 0,13792518 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,13115229 0,13987252 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,13115229 0,13981055 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,13115229 0,13974863 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,13115229 0,13968677 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,13303153 0,14162561 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,13303153 0,14156297 ! extracellular matrix organization GO:0030198 133 66 0,000 0,13303153 0,14150039 ! secondary metabolic process GO:0019748 116 66 0,000 0,13303153 0,14143786 ! developmental maturation GO:0021700 116 66 0,000 0,13303153 0,14137539 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,13490678 0,14330495 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,13490678 0,14324171 ! activation of MAPK activity GO:0000187 115 67 0,000 0,13490678 0,14317852 ! chromosome segregation GO:0007059 113 67 0,000 0,13490678 0,14311539 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,13490678 0,14305232 ! hexose catabolic process GO:0019320 104 67 0,000 0,13490678 0,1429893 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,13490678 0,14292634 ! adaptive immune response GO:0002250 119 67 0,000 0,13490678 0,14286343 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,13490678 0,14280058 ! amino acid transport GO:0006865 125 68 0,000 0,13677803 0,14471765 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,13677803 0,14465404 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,13677803 0,14459048 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 0,000 0,13677803 0,14452698 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,13677803 0,14446354 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,13677803 0,14440015 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,13864529 0,14630727 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,13864529 0,14624313 ! urogenital system development GO:0001655 137 69 0,000 0,13864529 0,14617904 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,13864529 0,14611501 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,13864529 0,14605104 ! antigen processing and presentation GO:0019882 104 69 0,000 0,13864529 0,14598712 ! appendage morphogenesis GO:0035107 135 70 0,000 0,14050858 0,14788436 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,1423679 0,14977576 ! reproductive structure development GO:0048608 113 71 0,000 0,1423679 0,1497103 ! appendage development GO:0048736 136 71 0,000 0,1423679 0,14964489 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,1423679 0,14957955 ! B cell activation GO:0042113 160 71 0,000 0,1423679 0,14951426 ! regulation of immune effector process GO:0002697 137 71 0,000 0,1423679 0,14944902 ! acute inflammatory response GO:0002526 113 72 0,000 0,14422326 0,15133064 ! regulation of caspase activity GO:0043281 122 72 0,000 0,14422326 0,15126467 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,14422326 0,15119876 ! carbohydrate transport GO:0008643 110 72 0,000 0,14422326 0,15113291 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,14422326 0,15106711 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,14422326 0,15100137 ! learning or memory GO:0007611 147 73 0,000 0,14607466 0,15287327 ! regulation of blood pressure GO:0008217 125 73 0,000 0,14607466 0,1528068 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,14607466 0,15274039 ! axon guidance GO:0007411 139 73 0,000 0,14607466 0,15267404 ! fertilization GO:0009566 90 73 0,000 0,14607466 0,15260775 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,14792212 0,15447076 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,14792212 0,15440374 ! neurotransmitter transport GO:0006836 123 74 0,000 0,14792212 0,15433679 ! meiosis GO:0007126 121 74 0,000 0,14792212 0,15426989 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,14792212 0,15420305 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,14792212 0,15413626 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,14792212 0,15406954 ! eye development GO:0001654 143 74 0,000 0,14792212 0,15400287 ! organelle localization GO:0051640 136 74 0,000 0,14792212 0,15393626 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,14976565 0,15578736 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,14976565 0,15572003 ! meiotic cell cycle GO:0051321 122 75 0,000 0,14976565 0,15565277 ! rhythmic process GO:0048511 128 75 0,000 0,14976565 0,15558556 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,14976565 0,15551841 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,15160525 0,15736076 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,15160525 0,1572929 ! defense response to bacterium GO:0042742 89 76 0,000 0,15160525 0,1572251 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,15160525 0,15715736 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,15160525 0,15708968 ! regulation of catabolic process GO:0009894 161 76 0,000 0,15160525 0,15702205 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,15344093 0,15885494 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,15344093 0,15878661 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,15344093 0,15871835 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,1552727 0,1605441 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,1552727 0,16047513 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,1552727 0,16040623 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,15710056 0,16222488 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,15710056 0,16215528 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,15710056 0,16208575 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,15710056 0,16201627 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,15710056 0,16194685 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,15892454 0,16375693 ! response to metal ion GO:0010038 140 80 0,000 0,15892454 0,16368683 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,15892454 0,16361679 ! protein import into nucleus GO:0006606 158 80 0,000 0,15892454 0,16354681 ! inorganic anion transport GO:0015698 138 80 0,000 0,15892454 0,16347689 ! T cell activation GO:0042110 168 81 0,000 0,16074462 0,16527844 ! digestion GO:0007586 112 81 0,000 0,16074462 0,16520784 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,16074462 0,1651373 ! nuclear import GO:0051170 161 81 0,000 0,16074462 0,16506682 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,16256083 0,16686065 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,16256083 0,16678949 ! response to drug GO:0042493 143 82 0,000 0,16256083 0,1667184 ! response to nutrient GO:0007584 125 82 0,000 0,16256083 0,16664736 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,16256083 0,16657639 ! regulation of lyase activity GO:0051339 160 83 0,000 0,16437317 0,16836179 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,16618164 0,17014171 ! regulation of ligase activity GO:0051340 142 84 0,000 0,16618164 0,17006934 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,16618164 0,16999704 ! response to unfolded protein GO:0006986 131 85 0,000 0,16798626 0,17177006 ! nucleosome assembly GO:0006334 122 85 0,000 0,16798626 0,17169709 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,16798626 0,17162418 ! amine biosynthetic process GO:0009309 138 86 0,000 0,16978704 0,17339033 ! response to inorganic substance GO:0010035 153 86 0,000 0,16978704 0,17331676 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,16978704 0,17324326 ! chromatin assembly GO:0031497 124 86 0,000 0,16978704 0,17316982 ! mitochondrion organization GO:0007005 148 86 0,000 0,16978704 0,17309645 ! alcohol catabolic process GO:0046164 130 86 0,000 0,16978704 0,17302313 ! amine transport GO:0015837 155 86 0,000 0,16978704 0,17294988 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,17158398 0,17470633 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,17158398 0,17463242 ! protein localization in nucleus GO:0034504 176 87 0,000 0,17158398 0,17455858 ! regulation of protein transport GO:0051223 154 87 0,000 0,17158398 0,1744848 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,17337708 0,17623374 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,17337708 0,17615932 ! regulation of DNA binding GO:0051101 155 88 0,000 0,17337708 0,17608496 ! regulation of neurological system process GO:0031644 148 88 0,000 0,17337708 0,17601066 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,17337708 0,17593643 ! cellular defense response GO:0006968 114 89 0,000 0,17516637 0,17767719 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,17516637 0,17760231 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,17695184 0,17933704 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,17695184 0,17926153 ! sex differentiation GO:0007548 145 90 0,000 0,17695184 0,17918608 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,17695184 0,1791107 ! sterol metabolic process GO:0016125 152 91 0,000 0,17873351 0,18083803 ! response to protein stimulus GO:0051789 149 91 0,000 0,17873351 0,18076201 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,17873351 0,18068606 ! regulation of defense response GO:0031347 149 92 0,000 0,18051138 0,18240671 ! nucleosome organization GO:0034728 138 92 0,000 0,18051138 0,18233014 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,18051138 0,18225362 ! vitamin metabolic process GO:0006766 139 92 0,000 0,18051138 0,18217717 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,18228546 0,18389049 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,18228546 0,18381342 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,18405576 0,1855208 ! female pregnancy GO:0007565 164 94 0,000 0,18405576 0,18544312 ! transcription initiation GO:0006352 153 94 0,000 0,18405576 0,18536549 ! regulation of T cell activation GO:0050863 158 94 0,000 0,18405576 0,18528793 ! forebrain development GO:0030900 188 95 0,000 0,18582229 0,18698805 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,18582229 0,18690987 ! leukocyte differentiation GO:0002521 202 96 0,000 0,18758504 0,1886041 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,18758504 0,18852532 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,18758504 0,1884466 ! positive regulation of immune response GO:0050778 156 96 0,000 0,18758504 0,18836795 ! detection of stimulus GO:0051606 151 96 0,000 0,18758504 0,18828937 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,18934405 0,18997572 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,18934405 0,18989653 ! protein ubiquitination GO:0016567 217 97 0,000 0,18934405 0,18981741 ! hormone metabolic process GO:0042445 157 97 0,000 0,18934405 0,18973835 ! regulation of protein localization GO:0032880 176 97 0,000 0,18934405 0,18965936 ! response to virus GO:0009615 160 98 0,000 0,1910993 0,19133787 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,1910993 0,19125828 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,1910993 0,19117876 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,19285081 0,19285081