pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/633-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! auditory receptor cell differentiation GO:0042491 36 17 4,000 1,673E-10 4,088E-07 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 4,000 7,066E-10 8,631E-07 ! inner ear receptor cell differentiation GO:0060113 42 22 4,000 7,066E-10 5,754E-07 ! mechanoreceptor differentiation GO:0042490 48 24 4,000 1,137E-09 6,944E-07 ! lung development GO:0030324 165 69 5,000 5,556E-09 2,715E-06 ! respiratory tube development GO:0030323 171 72 5,000 7,207E-09 2,934E-06 ! respiratory system development GO:0060541 175 74 5,000 8,518E-09 2,973E-06 ! inner ear development GO:0048839 89 53 4,000 7,339E-08 2,241E-05 ! ear development GO:0043583 114 66 4,000 2,24E-07 6,081E-05 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 1,62E-06 3,958E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 2,238E-06 4,971E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 9,899E-06 2,015E-03 ! G1 phase GO:0051318 44 22 2,000 1,145E-05 2,151E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,145E-05 1,999E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,213E-05 1,975E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,513E-05 2,31E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 1,702E-05 2,446E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 2,414E-05 3,276E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 3,298E-05 4,24E-03 ! positive regulation of muscle cell differentiation GO:0051149 13 5 1,000 3,919E-05 4,787E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,919E-05 4,559E-03 ! substrate-bound cell migration, cell extension GO:0006930 6 5 1,000 3,919E-05 4,352E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 3,919E-05 4,162E-03 ! cellular glucose homeostasis GO:0001678 6 5 1,000 3,919E-05 3,989E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 3,919E-05 3,829E-03 ! negative regulation of secretion GO:0051048 68 35 2,000 4,774E-05 4,486E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 5,652E-05 5,114E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 5,871E-05 5,122E-03 ! neural tube patterning GO:0021532 8 6 1,000 5,871E-05 4,945E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 5,871E-05 4,781E-03 ! mammary gland development GO:0030879 93 40 2,000 7,156E-05 5,639E-03 ! gliogenesis GO:0042063 91 41 2,000 7,71E-05 5,886E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 8,208E-05 6,076E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,208E-05 5,898E-03 ! vesicle fusion GO:0006906 20 7 1,000 8,208E-05 5,729E-03 ! cell differentiation in hindbrain GO:0021533 10 7 1,000 8,208E-05 5,57E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 8,208E-05 5,42E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 8,208E-05 5,277E-03 ! striated muscle cell differentiation GO:0051146 91 43 2,000 8,9E-05 5,575E-03 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 8,9E-05 5,436E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,02E-04 6,08E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,093E-04 6,358E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 1,093E-04 6,21E-03 ! Schwann cell differentiation GO:0014037 21 8 1,000 1,093E-04 6,069E-03 ! cardiac muscle cell differentiation GO:0055007 31 8 1,000 1,093E-04 5,934E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,093E-04 5,805E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,093E-04 5,681E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,093E-04 5,563E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,093E-04 5,449E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,403E-04 6,857E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,403E-04 6,723E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,403E-04 6,594E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,403E-04 6,469E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,752E-04 7,926E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,752E-04 7,782E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 1,752E-04 7,643E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,752E-04 7,509E-03 ! response to UV GO:0009411 120 55 2,000 1,86E-04 7,833E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 2,000 2,068E-04 8,564E-03 ! neuron fate specification GO:0048665 18 11 1,000 2,139E-04 8,708E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,139E-04 8,565E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 2,139E-04 8,427E-03 ! substrate-bound cell migration GO:0006929 14 11 1,000 2,139E-04 8,293E-03 ! positive regulation of neuron differentiation GO:0045666 22 11 1,000 2,139E-04 8,164E-03 ! cardiac cell differentiation GO:0035051 36 11 1,000 2,139E-04 8,038E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,563E-04 9,487E-03 ! protein complex disassembly GO:0043241 28 12 1,000 2,563E-04 9,346E-03 GO:0043624|cellular protein complex disassembly, ! focal adhesion formation GO:0048041 37 12 1,000 2,563E-04 9,208E-03 ! histone acetylation GO:0016573 27 12 1,000 2,563E-04 9,075E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,563E-04 8,945E-03 ! localization within membrane GO:0051668 26 12 1,000 2,563E-04 8,819E-03 ! cranial nerve development GO:0021545 23 12 1,000 2,563E-04 8,697E-03 ! organelle fusion GO:0048284 36 13 1,000 3,025E-04 0,01012392 ! endocrine pancreas development GO:0031018 25 13 1,000 3,025E-04 9,987E-03 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,025E-04 9,854E-03 ! gland morphogenesis GO:0022612 31 13 1,000 3,025E-04 9,724E-03 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 3,025E-04 9,598E-03 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 3,193E-04 0,01000136 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 3,193E-04 9,875E-03 ! negative regulation of cell growth GO:0030308 142 67 2,000 3,338E-04 0,01019384 ! lipid localization GO:0010876 32 14 1,000 3,525E-04 0,01063094 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 3,525E-04 0,0105013 ! negative regulation of cell size GO:0045792 144 69 2,000 3,641E-04 0,01071541 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 3,96E-04 0,011517 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,062E-04 0,01167412 ! regulation of vasodilation GO:0042312 27 15 1,000 4,062E-04 0,01153838 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 5,247E-04 0,01473502 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 5,247E-04 0,01456758 ! regulation of protein binding GO:0043393 33 17 1,000 5,247E-04 0,0144039 ! protein oligomerization GO:0051259 149 79 2,000 5,417E-04 0,0147035 ! muscle cell differentiation GO:0042692 178 81 2,000 5,828E-04 0,01564484 ! response to hypoxia GO:0001666 178 81 2,000 5,828E-04 0,01547479 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 5,896E-04 0,01548739 ! cell-substrate junction assembly GO:0007044 56 18 1,000 5,896E-04 0,01532263 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 5,896E-04 0,01516134 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 5,896E-04 0,01500341 ! nerve development GO:0021675 34 18 1,000 5,896E-04 0,01484874 ! response to oxygen levels GO:0070482 183 83 2,000 6,258E-04 0,01559989 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 6,581E-04 0,01623939 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 6,581E-04 0,01607699 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 6,581E-04 0,01591781 ! negative regulation of transport GO:0051051 164 85 2,000 6,708E-04 0,01606597 ! negative regulation of growth GO:0045926 168 85 2,000 6,708E-04 0,01590999 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,303E-04 0,0171541 ! protein amino acid acetylation GO:0006473 41 20 1,000 7,303E-04 0,01699072 ! pancreas development GO:0031016 40 20 1,000 7,303E-04 0,01683043 ! actin filament bundle formation GO:0051017 47 20 1,000 7,303E-04 0,01667314 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 7,303E-04 0,01651876 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 7,303E-04 0,01636721 ! lipid phosphorylation GO:0046834 43 21 1,000 8,061E-04 0,01790248 ! cellular macromolecular complex disassembly GO:0034623 44 21 1,000 8,061E-04 0,0177412 ! regulation of vasoconstriction GO:0019229 40 21 1,000 8,061E-04 0,01758279 ! gland development GO:0048732 220 91 2,000 8,18E-04 0,01768513 ! regulation of cell adhesion GO:0030155 241 92 2,000 8,444E-04 0,01809506 ! inactivation of MAPK activity GO:0000188 45 22 1,000 8,856E-04 0,01881221 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 8,856E-04 0,01865003 ! positive regulation of B cell activation GO:0050871 42 22 1,000 8,856E-04 0,01849063 ! cellular response to starvation GO:0009267 37 22 1,000 8,856E-04 0,01833393 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 1,000 9,686E-04 0,01988558 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 9,686E-04 0,01971987 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 9,686E-04 0,0195569 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,055E-03 0,02113262 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,055E-03 0,02096081 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,055E-03 0,02079177 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,055E-03 0,02062543 ! membrane depolarization GO:0051899 45 24 1,000 1,055E-03 0,02046174 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,055E-03 0,02030062 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,055E-03 0,02014202 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,146E-03 0,02169576 ! vasculogenesis GO:0001570 49 25 1,000 1,146E-03 0,02152887 ! macromolecular complex disassembly GO:0032984 54 26 1,000 1,239E-03 0,02311505 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,239E-03 0,02293993 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,239E-03 0,02276745 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,239E-03 0,02259755 ! neural crest cell development GO:0014032 59 26 1,000 1,239E-03 0,02243016 GO:0014033|neural crest cell differentiation, ! regulation of blood coagulation GO:0030193 46 26 1,000 1,239E-03 0,02226523 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 1,239E-03 0,02210271 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,337E-03 0,02366738 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 1,337E-03 0,02349711 ! response to starvation GO:0042594 47 27 1,000 1,337E-03 0,02332928 ! cellular response to nutrient levels GO:0031669 45 27 1,000 1,337E-03 0,02316382 ! neuron fate commitment GO:0048663 52 28 1,000 1,438E-03 0,02473803 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,438E-03 0,02456504 ! protein amino acid acylation GO:0043543 59 28 1,000 1,438E-03 0,02439445 ! vesicle docking GO:0048278 55 28 1,000 1,438E-03 0,02422621 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 1,542E-03 0,0258092 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 1,542E-03 0,02563363 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 1,65E-03 0,02724386 ! regulation of B cell activation GO:0050864 55 30 1,000 1,65E-03 0,02706101 ! regulation of coagulation GO:0050818 52 30 1,000 1,65E-03 0,02688061 ! cell junction assembly GO:0034329 85 31 1,000 1,762E-03 0,02850735 ! erythrocyte differentiation GO:0030218 62 31 1,000 1,762E-03 0,0283198 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 1,762E-03 0,0281347 ! peripheral nervous system development GO:0007422 68 32 1,000 1,877E-03 0,02977705 ! hindbrain development GO:0030902 65 32 1,000 1,877E-03 0,02958494 ! cholesterol homeostasis GO:0042632 60 33 1,000 1,996E-03 0,03125144 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 1,996E-03 0,03105238 ! glial cell differentiation GO:0010001 67 34 1,000 2,118E-03 0,03274209 ! cholesterol transport GO:0030301 62 34 1,000 2,118E-03 0,03253617 ! formation of primary germ layer GO:0001704 76 34 1,000 2,118E-03 0,03233282 ! cell fate specification GO:0001708 56 34 1,000 2,118E-03 0,03213199 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,118E-03 0,03193365 ! membrane docking GO:0022406 69 35 1,000 2,243E-03 0,03361787 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 2,243E-03 0,03341288 ! sterol transport GO:0015918 63 35 1,000 2,243E-03 0,03321038 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,243E-03 0,03301031 ! regulation of muscle development GO:0048634 82 36 1,000 2,372E-03 0,03469805 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 2,504E-03 0,03641549 ! cell junction organization GO:0034330 96 37 1,000 2,504E-03 0,03620002 ! tissue remodeling GO:0048771 78 37 1,000 2,504E-03 0,03598707 ! regulation of microtubule-based process GO:0032886 86 37 1,000 2,504E-03 0,03577662 ! neutral lipid metabolic process GO:0006638 54 38 1,000 2,64E-03 0,0374963 GO:0006639|acylglycerol metabolic process, ! cellular response to insulin stimulus GO:0032869 85 38 1,000 2,64E-03 0,03727956 ! carbohydrate homeostasis GO:0033500 59 39 1,000 2,779E-03 0,03901854 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 1,000 2,779E-03 0,03879557 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 2,779E-03 0,03857514 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! lipid homeostasis GO:0055088 75 40 1,000 2,922E-03 0,04032402 ! glycerol ether metabolic process GO:0006662 57 40 1,000 2,922E-03 0,04009748 ! mesenchymal cell development GO:0014031 94 41 1,000 3,067E-03 0,04186431 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! organic ether metabolic process GO:0018904 59 42 1,000 3,217E-03 0,04365705 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 3,217E-03 0,04341585 ! epithelial cell differentiation GO:0030855 83 43 1,000 3,369E-03 0,04522524 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 3,684E-03 0,04918474 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 3,684E-03 0,04891743 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 3,847E-03 0,05079908 ! neural tube development GO:0021915 91 47 1,000 4,013E-03 0,0527037 ! response to insulin stimulus GO:0032868 98 47 1,000 4,013E-03 0,05242186 ! positive regulation of cell cycle GO:0045787 96 48 1,000 4,182E-03 0,05434014 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 4,182E-03 0,05405262 ! cellular component disassembly GO:0022411 89 48 1,000 4,182E-03 0,05376814 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 4,354E-03 0,05569096 ! protein homooligomerization GO:0051260 84 49 1,000 4,354E-03 0,0554009 ! endocrine system development GO:0035270 109 50 1,000 4,53E-03 0,05733645 ! regulation of ossification GO:0030278 123 50 1,000 4,53E-03 0,0570409 ! Notch signaling pathway GO:0007219 111 52 1,000 4,891E-03 0,06126943 ! histone modification GO:0016570 104 52 1,000 4,891E-03 0,06095683 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 4,891E-03 0,0606474 ! vesicle organization GO:0016050 127 53 1,000 5,076E-03 0,06262684 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 5,076E-03 0,06231213 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 5,076E-03 0,06200057 ! activation of phospholipase C activity GO:0007202 110 54 1,000 5,264E-03 0,06398257 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 5,264E-03 0,06366582 ! membrane fusion GO:0006944 122 54 1,000 5,264E-03 0,0633522 ! covalent chromatin modification GO:0016569 115 54 1,000 5,264E-03 0,06304165 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 5,456E-03 0,06501782 ! regulation of protein polymerization GO:0032271 117 55 1,000 5,456E-03 0,0647022 ! negative regulation of cell motion GO:0051271 142 55 1,000 5,456E-03 0,06438963 ! regulation of bone remodeling GO:0046850 143 57 1,000 5,849E-03 0,06869309 ! regulation of phospholipase activity GO:0010517 113 57 1,000 5,849E-03 0,06836442 ! positive regulation of cell migration GO:0030335 137 58 1,000 6,05E-03 0,07037834 ! gastrulation GO:0007369 122 58 1,000 6,05E-03 0,07004479 ! regulation of tissue remodeling GO:0034103 146 58 1,000 6,05E-03 0,06971439 ! positive regulation of organelle organization GO:0010638 108 58 1,000 6,05E-03 0,0693871 ! positive regulation of lipase activity GO:0060193 115 58 1,000 6,05E-03 0,06906286 ! lipid modification GO:0030258 112 60 1,000 6,461E-03 0,07341832 ! regulation of endocytosis GO:0030100 104 60 1,000 6,461E-03 0,07307842 ! regulation of homeostatic process GO:0032844 148 62 1,000 6,885E-03 0,07751503 ! regulation of protein complex assembly GO:0043254 132 63 1,000 7,102E-03 0,07958702 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 7,322E-03 0,08167429 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 7,322E-03 0,08130304 ! positive regulation of cell motion GO:0051272 157 65 1,000 7,544E-03 0,0833974 ! myeloid cell differentiation GO:0030099 126 67 1,000 7,999E-03 0,08802429 ! regulation of lipase activity GO:0060191 137 68 1,000 8,231E-03 0,09016924 ! cell projection assembly GO:0030031 138 68 1,000 8,231E-03 0,0897667 ! homeostasis of number of cells GO:0048872 131 69 1,000 8,466E-03 0,09191744 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 8,466E-03 0,09151072 ! cell redox homeostasis GO:0045454 114 70 1,000 8,703E-03 0,093667 ! cell cycle checkpoint GO:0000075 145 71 1,000 8,944E-03 0,09583627 ! actin filament organization GO:0007015 167 72 1,000 9,188E-03 0,09801823 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 9,188E-03 0,09759206 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 9,948E-03 0,10521141 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 9,948E-03 0,10475792 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 9,948E-03 0,10430831 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 9,948E-03 0,10386255 ! positive regulation of helicase activity GO:0051096 12 5 0,000 9,948E-03 0,10342058 ! neuron fate determination GO:0048664 7 5 0,000 9,948E-03 0,10298236 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 9,948E-03 0,10254783 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 9,948E-03 0,10211696 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 9,948E-03 0,10168969 ! polyol transport GO:0015791 12 5 0,000 9,948E-03 0,10126599 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 9,948E-03 0,10084579 ! response to superoxide GO:0000303 10 5 0,000 9,948E-03 0,10042908 ! negative regulation of bone resorption GO:0045779 10 5 0,000 9,948E-03 0,10001579 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 9,948E-03 0,09960589 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 9,948E-03 0,09919933 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 9,948E-03 0,09879608 ! female meiosis GO:0007143 10 5 0,000 9,948E-03 0,0983961 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 9,948E-03 0,09799934 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 9,948E-03 0,09760577 ! hypothalamus development GO:0021854 9 5 0,000 9,948E-03 0,09721535 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 9,948E-03 0,09682803 ! cobalt ion transport GO:0006824 11 5 0,000 9,948E-03 0,0964438 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 9,948E-03 0,09606259 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 9,948E-03 0,0956844 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 9,948E-03 0,09530916 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 9,948E-03 0,09493686 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 9,948E-03 0,09456746 ! embryonic camera-type eye development GO:0031076 12 5 0,000 9,948E-03 0,09420092 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 9,948E-03 0,09383721 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 9,948E-03 0,09347629 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 9,948E-03 0,09311815 ! transposition GO:0032196 9 5 0,000 9,948E-03 0,09276273 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 9,948E-03 0,09241002 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 9,948E-03 0,09205999 ! negative chemotaxis GO:0050919 16 5 0,000 9,948E-03 0,09171259 ! positive regulation of histone modification GO:0031058 6 5 0,000 9,948E-03 0,09136781 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 9,948E-03 0,0910256 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 9,948E-03 0,09068596 ! behavioral response to pain GO:0048266 10 5 0,000 9,948E-03 0,09034883 ! clathrin coat assembly GO:0048268 15 5 0,000 9,948E-03 0,09001421 ! Notch receptor processing GO:0007220 11 5 0,000 9,948E-03 0,08968205 ! regulation of dopamine uptake GO:0051584 9 5 0,000 9,948E-03 0,08935234 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 9,948E-03 0,08902504 ! micturition GO:0060073 9 5 0,000 9,948E-03 0,08870013 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 9,948E-03 0,08837759 ! copulation GO:0007620 9 5 0,000 9,948E-03 0,08805738 ! glial cell fate commitment GO:0021781 14 5 0,000 9,948E-03 0,08773948 ! protein maturation by protein folding GO:0022417 14 5 0,000 9,948E-03 0,08742387 ! bioluminescence GO:0008218 9 5 0,000 9,948E-03 0,08711052 ! spermidine metabolic process GO:0008216 7 5 0,000 9,948E-03 0,08679942 ! regulation of potassium ion transport GO:0043266 10 5 0,000 9,948E-03 0,08649052 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 9,948E-03 0,08618382 ! apoptotic cell clearance GO:0043277 23 5 0,000 9,948E-03 0,08587928 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 9,948E-03 0,08557689 ! lipoprotein particle clearance GO:0034381 10 5 0,000 9,948E-03 0,08527662 ! grooming behavior GO:0007625 6 5 0,000 9,948E-03 0,08497845 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 9,948E-03 0,08468236 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 9,948E-03 0,08438832 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 9,948E-03 0,08409632 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 9,948E-03 0,08380633 ! response to protozoan GO:0001562 13 5 0,000 9,948E-03 0,08351834 ! positive regulation of glycolysis GO:0045821 13 5 0,000 9,948E-03 0,08323232 ! lymph vessel development GO:0001945 10 5 0,000 9,948E-03 0,08294825 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 9,948E-03 0,08266611 ! endochondral ossification GO:0001958 17 5 0,000 9,948E-03 0,08238589 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 9,948E-03 0,08210756 ! single strand break repair GO:0000012 8 5 0,000 9,948E-03 0,0818311 ! parathyroid gland development GO:0060017 14 5 0,000 9,948E-03 0,0815565 ! anagen GO:0042640 7 5 0,000 9,948E-03 0,08128373 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 9,948E-03 0,08101279 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 9,948E-03 0,08074364 ! cytokine secretion GO:0050663 15 5 0,000 9,948E-03 0,08047628 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 9,948E-03 0,08021068 ! ceramide catabolic process GO:0046514 7 5 0,000 9,948E-03 0,07994683 ! skeletal myofibril assembly GO:0014866 12 5 0,000 9,948E-03 0,07968471 ! smooth muscle tissue development GO:0048745 32 5 0,000 9,948E-03 0,0794243 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 9,948E-03 0,07916559 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 9,948E-03 0,07890856 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 9,948E-03 0,07865319 ! cardiac muscle fiber development GO:0048739 12 5 0,000 9,948E-03 0,07839947 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 9,948E-03 0,07814738 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 9,948E-03 0,07789691 ! neutrophil mediated immunity GO:0002446 7 5 0,000 9,948E-03 0,07764804 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 9,948E-03 0,07740075 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 9,948E-03 0,07715504 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 9,948E-03 0,07691087 ! glycine biosynthetic process GO:0006545 7 5 0,000 9,948E-03 0,07666825 ! microvillus organization GO:0032528 8 5 0,000 9,948E-03 0,07642716 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 9,948E-03 0,07618758 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 9,948E-03 0,07594949 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 9,948E-03 0,07571289 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 9,948E-03 0,07547775 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 9,948E-03 0,07524408 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 9,948E-03 0,07501184 ! polyol catabolic process GO:0046174 9 5 0,000 9,948E-03 0,07478104 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 9,948E-03 0,07455165 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 9,948E-03 0,07432366 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 9,948E-03 0,07409706 ! muscle cell migration GO:0014812 8 5 0,000 9,948E-03 0,07387184 ! mitochondrial fission GO:0000266 8 5 0,000 9,948E-03 0,07364799 ! sister chromatid cohesion GO:0007062 15 5 0,000 9,948E-03 0,07342549 ! response to tumor necrosis factor GO:0034612 10 5 0,000 9,948E-03 0,07320433 ! mRNA transcription GO:0009299 10 5 0,000 9,948E-03 0,07298449 ! nerve growth factor processing GO:0032455 9 5 0,000 9,948E-03 0,07276598 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 9,948E-03 0,07254877 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 9,948E-03 0,07233285 ! anaerobic glycolysis GO:0019642 6 5 0,000 9,948E-03 0,07211821 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 9,948E-03 0,07190484 ! monocyte activation GO:0042117 10 5 0,000 9,948E-03 0,07169273 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 9,948E-03 0,07148187 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 9,948E-03 0,07127225 ! response to food GO:0032094 6 5 0,000 9,948E-03 0,07106385 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 9,948E-03 0,07085667 ! positive regulation of transporter activity GO:0032411 8 5 0,000 9,948E-03 0,07065069 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 9,948E-03 0,0704459 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 9,948E-03 0,0702423 ! forebrain neuron development GO:0021884 13 5 0,000 9,948E-03 0,07003987 ! lipoprotein catabolic process GO:0042159 11 5 0,000 9,948E-03 0,06983861 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 9,948E-03 0,0696385 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 9,948E-03 0,06943953 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 9,948E-03 0,0692417 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 9,948E-03 0,06904499 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 9,948E-03 0,0688494 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 9,948E-03 0,06865491 ! lipid glycosylation GO:0030259 7 5 0,000 9,948E-03 0,06846151 ! nucleobase transport GO:0015851 6 5 0,000 9,948E-03 0,0682692 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 9,948E-03 0,06807797 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 9,948E-03 0,06788781 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 9,948E-03 0,06769871 ! basic amino acid transport GO:0015802 12 5 0,000 9,948E-03 0,06751066 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 9,948E-03 0,06732365 ! actin nucleation GO:0045010 11 5 0,000 9,948E-03 0,06713767 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 9,948E-03 0,06695272 ! depurination GO:0045007 5 5 0,000 9,948E-03 0,06676878 ! depyrimidination GO:0045008 10 5 0,000 9,948E-03 0,06658585 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 9,948E-03 0,06640392 ! regulation of centrosome cycle GO:0046605 7 5 0,000 9,948E-03 0,06622299 ! G2/M transition checkpoint GO:0031576 8 5 0,000 9,948E-03 0,06604303 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 9,948E-03 0,06586406 ! zinc ion homeostasis GO:0055069 9 5 0,000 9,948E-03 0,06568604 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 9,948E-03 0,06550899 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 9,948E-03 0,06533289 ! forebrain morphogenesis GO:0048853 13 5 0,000 9,948E-03 0,06515774 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 9,948E-03 0,06498352 ! activated T cell proliferation GO:0050798 16 5 0,000 9,948E-03 0,06481023 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 9,948E-03 0,06463786 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 9,948E-03 0,06446641 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 9,948E-03 0,06429586 ! positive regulation of organ growth GO:0046622 6 5 0,000 9,948E-03 0,06412622 ! gamma-delta T cell activation GO:0046629 6 5 0,000 9,948E-03 0,06395746 ! response to arsenic GO:0046685 11 5 0,000 9,948E-03 0,0637896 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 9,948E-03 0,06362261 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 9,948E-03 0,06345649 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 9,948E-03 0,06329124 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 9,948E-03 0,06312685 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 9,948E-03 0,06296331 ! response to mercury ion GO:0046689 8 5 0,000 9,948E-03 0,06280061 ! response to cadmium ion GO:0046686 7 5 0,000 9,948E-03 0,06263875 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 9,948E-03 0,06247773 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 9,948E-03 0,06231753 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 9,948E-03 0,06215815 ! bile acid biosynthetic process GO:0006699 7 5 0,000 9,948E-03 0,06199958 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 9,948E-03 0,06184182 ! ganglioside catabolic process GO:0006689 12 5 0,000 9,948E-03 0,06168486 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 9,948E-03 0,0615287 ! decidualization GO:0046697 11 5 0,000 9,948E-03 0,06137332 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 9,948E-03 0,06121873 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 9,948E-03 0,06106492 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 9,948E-03 0,06091187 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 9,948E-03 0,06075959 ! embryonic cleavage GO:0040016 6 5 0,000 9,948E-03 0,06060807 ! peroxisome fission GO:0016559 5 5 0,000 9,948E-03 0,0604573 ! histone demethylation GO:0016577 13 5 0,000 9,948E-03 0,06030729 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 9,948E-03 0,06015801 ! mitotic recombination GO:0006312 9 5 0,000 9,948E-03 0,06000947 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 9,948E-03 0,05986167 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 9,948E-03 0,05971459 ! metaphase plate congression GO:0051310 7 5 0,000 9,948E-03 0,05956823 ! regulation of sterol transport GO:0032371 7 5 0,000 9,948E-03 0,05942258 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 9,948E-03 0,05927765 ! enteric nervous system development GO:0048484 8 5 0,000 9,948E-03 0,05913342 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 9,948E-03 0,05898989 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 9,948E-03 0,05884706 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 9,948E-03 0,05870492 ! muscle cell proliferation GO:0033002 12 5 0,000 9,948E-03 0,05856346 ! skeletal muscle regeneration GO:0043403 8 5 0,000 9,948E-03 0,05842268 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 9,948E-03 0,05828258 ! B cell homeostasis GO:0001782 13 5 0,000 9,948E-03 0,05814315 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 9,948E-03 0,05800438 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 9,948E-03 0,05786628 ! metaphase GO:0051323 11 5 0,000 9,948E-03 0,05772883 ! melatonin biosynthetic process GO:0030187 7 5 0,000 9,948E-03 0,05759203 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 9,948E-03 0,05745588 ! cellular response to nutrient GO:0031670 8 5 0,000 9,948E-03 0,05732037 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 9,948E-03 0,0571855 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 9,948E-03 0,05705126 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 9,948E-03 0,05691765 ! regulation of hair follicle development GO:0051797 10 5 0,000 9,948E-03 0,05678466 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 9,948E-03 0,0566523 ! response to redox state GO:0051775 6 5 0,000 9,948E-03 0,05652055 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 9,948E-03 0,05638941 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 9,948E-03 0,05625888 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 9,948E-03 0,05612895 ! brown fat cell differentiation GO:0050873 7 5 0,000 9,948E-03 0,05599962 ! regulation of telomerase activity GO:0051972 7 5 0,000 9,948E-03 0,05587089 ! galactolipid metabolic process GO:0019374 7 5 0,000 9,948E-03 0,05574274 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 9,948E-03 0,05561519 ! porphyrin catabolic process GO:0006787 12 5 0,000 9,948E-03 0,05548821 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 9,948E-03 0,05536181 ! striatum development GO:0021756 14 5 0,000 9,948E-03 0,05523599 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 9,948E-03 0,05511074 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 9,948E-03 0,05498606 ! glial cell migration GO:0008347 10 5 0,000 9,948E-03 0,05486193 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 9,948E-03 0,05473837 ! neural plate morphogenesis GO:0001839 7 5 0,000 9,948E-03 0,05461536 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 9,948E-03 0,05449291 ! somatic stem cell maintenance GO:0035019 15 5 0,000 9,948E-03 0,054371 ! T cell activation during immune response GO:0002286 9 5 0,000 9,948E-03 0,05424963 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 9,948E-03 0,05412881 ! negative regulation of lipase activity GO:0060192 8 5 0,000 9,948E-03 0,05400853 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 9,948E-03 0,05388877 ! neuroprotection GO:0043526 8 5 0,000 9,948E-03 0,05376955 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 9,948E-03 0,05365085 ! regulation of sensory perception GO:0051931 8 5 0,000 9,948E-03 0,05353268 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 9,948E-03 0,05341503 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 9,948E-03 0,05329789 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 9,948E-03 0,05318126 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 9,948E-03 0,05306515 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 9,948E-03 0,05294953 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 9,948E-03 0,05283443 ! sequestering of calcium ion GO:0051208 7 5 0,000 9,948E-03 0,05271982 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 9,948E-03 0,05260571 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 9,948E-03 0,05249209 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 9,948E-03 0,05237896 ! spindle assembly GO:0051225 6 5 0,000 9,948E-03 0,05226631 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 9,948E-03 0,05215416 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 9,948E-03 0,05204248 ! protein palmitoylation GO:0018345 12 5 0,000 9,948E-03 0,05193127 ! drug metabolic process GO:0017144 7 5 0,000 9,948E-03 0,05182055 ! stem cell division GO:0017145 11 5 0,000 9,948E-03 0,05171029 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 9,948E-03 0,0516005 ! organ regeneration GO:0031100 7 5 0,000 9,948E-03 0,05149118 ! carnitine metabolic process GO:0009437 8 5 0,000 9,948E-03 0,05138232 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 9,948E-03 0,05127392 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,01019239 0,05242108 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01045079 0,05363713 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,01045079 0,05352469 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01071208 0,05474812 ! blood coagulation GO:0007596 151 79 1,000 0,01097624 0,05598113 GO:0050817|coagulation, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01151316 0,05859719 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,01178589 0,05986056 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01178589 0,05973637 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01192629 0,06032282 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01192629 0,06019818 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01192629 0,06007406 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01192629 0,05995045 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01192629 0,05982735 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01192629 0,05970475 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01192629 0,05958266 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01192629 0,05946106 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01192629 0,05933996 ! response to oxygen radical GO:0000305 11 6 0,000 0,01192629 0,05921935 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01192629 0,05909923 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01192629 0,0589796 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01192629 0,05886045 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01192629 0,05874177 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01192629 0,05862358 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01192629 0,05850586 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01192629 0,05838862 ! forebrain regionalization GO:0021871 9 6 0,000 0,01192629 0,05827184 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01192629 0,05815553 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01192629 0,05803968 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01192629 0,05792429 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01192629 0,05780937 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01192629 0,05769489 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01192629 0,05758087 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01192629 0,0574673 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01192629 0,05735417 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01192629 0,05724149 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01192629 0,05712926 ! malate metabolic process GO:0006108 13 6 0,000 0,01192629 0,05701746 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01192629 0,05690609 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01192629 0,05679517 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01192629 0,05668467 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01192629 0,0565746 ! protein refolding GO:0042026 15 6 0,000 0,01192629 0,05646496 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01192629 0,05635575 ! opsonization GO:0008228 8 6 0,000 0,01192629 0,05624695 ! mating behavior GO:0007617 7 6 0,000 0,01192629 0,05613857 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01192629 0,05603062 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01192629 0,05592307 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01192629 0,05581594 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01192629 0,05570922 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01192629 0,0556029 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01192629 0,05549699 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01192629 0,05539148 ! toxin metabolic process GO:0009404 11 6 0,000 0,01192629 0,05528638 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01192629 0,05518167 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01192629 0,05507735 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01192629 0,05497343 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01192629 0,05486991 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01192629 0,05476677 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01192629 0,05466402 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01192629 0,05456165 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01192629 0,05445966 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01192629 0,05435806 ! thymic T cell selection GO:0045061 16 6 0,000 0,01192629 0,05425683 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01192629 0,05415599 ! protein lipoylation GO:0009249 10 6 0,000 0,01192629 0,05405551 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01192629 0,05395541 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01192629 0,05385568 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01192629 0,05375631 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01192629 0,05365731 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01192629 0,05355868 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01192629 0,0534604 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01192629 0,05336249 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01192629 0,05326494 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01192629 0,05316774 ! hyperosmotic response GO:0006972 10 6 0,000 0,01192629 0,05307089 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01192629 0,0529744 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01192629 0,05287826 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01192629 0,05278246 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01192629 0,05268702 ! urea metabolic process GO:0019627 7 6 0,000 0,01192629 0,05259191 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01192629 0,05249715 ! neutrophil activation GO:0042119 7 6 0,000 0,01192629 0,05240273 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01192629 0,05230865 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01192629 0,05221491 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01192629 0,0521215 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01192629 0,05202843 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01192629 0,05193569 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01192629 0,05184327 ! neuron apoptosis GO:0051402 15 6 0,000 0,01192629 0,05175119 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01192629 0,05165943 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01192629 0,051568 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01192629 0,05147689 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01192629 0,0513861 ! carnitine transport GO:0015879 10 6 0,000 0,01192629 0,05129563 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01192629 0,05120548 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01192629 0,05111565 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01192629 0,05102613 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01192629 0,05093692 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01192629 0,05084803 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01192629 0,05075944 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01192629 0,05067117 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01192629 0,05058319 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01192629 0,05049553 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01192629 0,05040817 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01192629 0,05032111 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01192629 0,05023435 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01192629 0,05014788 ! response to UV-C GO:0010225 14 6 0,000 0,01192629 0,05006172 ! astrocyte development GO:0014002 16 6 0,000 0,01192629 0,04997585 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01192629 0,04989027 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01192629 0,04980499 ! interaction with symbiont GO:0051702 14 6 0,000 0,01192629 0,04972 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01192629 0,0496353 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01192629 0,04955088 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01192629 0,04946676 ! response to copper ion GO:0046688 10 6 0,000 0,01192629 0,04938292 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01192629 0,04929936 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01192629 0,04921608 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01192629 0,04913309 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01192629 0,04905037 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01192629 0,04896793 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01192629 0,04888577 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01192629 0,04880389 ! hair follicle maturation GO:0048820 8 6 0,000 0,01192629 0,04872227 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01192629 0,04864094 ! Schwann cell development GO:0014044 15 6 0,000 0,01192629 0,04855987 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01192629 0,04847907 ! response to pheromone GO:0019236 6 6 0,000 0,01192629 0,04839854 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01192629 0,04831828 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01192629 0,04823828 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01192629 0,04815855 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01192629 0,04807908 ! subpallium development GO:0021544 15 6 0,000 0,01192629 0,04799987 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01192629 0,04792092 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01192629 0,04784223 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01192629 0,0477638 ! G2 phase GO:0051319 16 6 0,000 0,01192629 0,04768563 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01192629 0,04760771 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01192629 0,04753005 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01192629 0,04745264 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01192629 0,04737548 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01192629 0,04729857 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01192629 0,04722191 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01192629 0,0471455 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01192629 0,04706934 ! receptor internalization GO:0031623 11 6 0,000 0,01192629 0,04699342 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01192629 0,04691775 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01192629 0,04684232 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01192629 0,04676713 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01192629 0,04669218 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01192629 0,04661747 ! protein deubiquitination GO:0016579 16 6 0,000 0,01192629 0,046543 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01192629 0,04646877 ! protein destabilization GO:0031648 9 6 0,000 0,01192629 0,04639478 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01192629 0,04632102 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01192629 0,04624749 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01192629 0,0461742 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01192629 0,04610114 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01192629 0,04602831 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01192629 0,04595571 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01192629 0,04588334 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01192629 0,0458112 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01192629 0,04573928 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01192629 0,04566759 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01192629 0,04559612 ! neural plate development GO:0001840 9 6 0,000 0,01192629 0,04552488 ! catecholamine transport GO:0051937 9 6 0,000 0,01192629 0,04545385 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01192629 0,04538305 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01192629 0,04531247 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01192629 0,04524211 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01192629 0,04517197 ! maternal placenta development GO:0001893 12 6 0,000 0,01192629 0,04510204 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01192629 0,04503233 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01192629 0,04496284 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01192629 0,04489356 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01192629 0,04482449 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01192629 0,04475564 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01192629 0,04468699 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01192629 0,04461856 GO:0055081|anion homeostasis, ! exocytosis GO:0006887 153 83 1,000 0,01206145 0,04505522 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01206145 0,04498644 GO:0045937|positive regulation of phosphate metabolic process, ! hemostasis GO:0007599 165 85 1,000 0,01262101 0,0470017 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,01262101 0,04693016 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01262101 0,04685884 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01290498 0,04784047 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 194 89 1,000 0,01377355 0,050983 ! tRNA transcription GO:0009304 17 7 0,000 0,01390032 0,05137441 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01390032 0,05129681 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01390032 0,05121944 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01390032 0,0511423 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01390032 0,05106539 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01390032 0,05098872 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01390032 0,05091227 ! sleep GO:0030431 16 7 0,000 0,01390032 0,05083606 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01390032 0,05076007 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01390032 0,05068431 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01390032 0,05060877 ! prostate gland development GO:0030850 14 7 0,000 0,01390032 0,05053346 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01390032 0,05045837 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01390032 0,05038351 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01390032 0,05030887 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01390032 0,05023445 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01390032 0,05016025 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01390032 0,05008626 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01390032 0,0500125 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01390032 0,04993895 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01390032 0,04986562 ! glycolipid transport GO:0046836 11 7 0,000 0,01390032 0,0497925 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01390032 0,0497196 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01390032 0,04964691 ! neuron adhesion GO:0007158 14 7 0,000 0,01390032 0,04957443 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01390032 0,04950217 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01390032 0,04943011 ! mRNA stabilization GO:0048255 18 7 0,000 0,01390032 0,04935826 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01390032 0,04928663 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01390032 0,0492152 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01390032 0,04914397 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01390032 0,04907296 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01390032 0,04900214 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01390032 0,04893154 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01390032 0,04886113 ! lipoprotein transport GO:0042953 14 7 0,000 0,01390032 0,04879093 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01390032 0,04872093 ! rhythmic behavior GO:0007622 17 7 0,000 0,01390032 0,04865113 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01390032 0,04858153 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01390032 0,04851212 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01390032 0,04844292 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01390032 0,04837391 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01390032 0,0483051 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01390032 0,04823649 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01390032 0,04816807 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01390032 0,04809984 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01390032 0,04803181 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01390032 0,04796396 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01390032 0,04789631 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01390032 0,04782885 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01390032 0,04776158 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01390032 0,0476945 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01390032 0,04762761 ! spinal cord patterning GO:0021511 14 7 0,000 0,01390032 0,04756091 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01390032 0,04749439 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01390032 0,04742805 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01390032 0,04736191 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01390032 0,04729594 ! adrenal gland development GO:0030325 17 7 0,000 0,01390032 0,04723016 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01390032 0,04716456 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01390032 0,04709915 ! ovulation GO:0030728 10 7 0,000 0,01390032 0,04703391 ! adenohypophysis development GO:0021984 11 7 0,000 0,01390032 0,04696886 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01390032 0,04690399 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01390032 0,04683929 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01390032 0,04677477 ! microtubule nucleation GO:0007020 21 7 0,000 0,01390032 0,04671044 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01390032 0,04664627 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01390032 0,04658229 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01390032 0,04651847 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01390032 0,04645484 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01390032 0,04639137 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01390032 0,04632808 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01390032 0,04626497 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01390032 0,04620202 ! galactose metabolic process GO:0006012 13 7 0,000 0,01390032 0,04613925 ! response to dietary excess GO:0002021 8 7 0,000 0,01390032 0,04607664 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01390032 0,04601421 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01390032 0,04595194 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01390032 0,04588985 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01390032 0,04582792 ! organ growth GO:0035265 15 7 0,000 0,01390032 0,04576615 ! nucleoside transport GO:0015858 11 7 0,000 0,01390032 0,04570456 ! nucleoside salvage GO:0043174 11 7 0,000 0,01390032 0,04564313 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01390032 0,04558186 ! male sex determination GO:0030238 15 7 0,000 0,01390032 0,04552076 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01390032 0,04545982 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01390032 0,04539905 ! parturition GO:0007567 16 7 0,000 0,01390032 0,04533843 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01390032 0,04527798 ! rRNA modification GO:0000154 14 7 0,000 0,01390032 0,04521769 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01390032 0,04515756 ! spindle checkpoint GO:0031577 16 7 0,000 0,01390032 0,04509759 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01390032 0,04503778 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01390032 0,04497813 ! monocyte differentiation GO:0030224 16 7 0,000 0,01390032 0,04491863 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01390032 0,04485929 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01390032 0,04480011 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01390032 0,04474109 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01390032 0,04468222 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01390032 0,0446235 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01390032 0,04456494 ! fibrinolysis GO:0042730 11 7 0,000 0,01390032 0,04450654 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01390032 0,04444828 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01390032 0,04439018 ! eating behavior GO:0042755 8 7 0,000 0,01390032 0,04433223 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01390032 0,04427443 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01390032 0,04421678 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01390032 0,04415928 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01390032 0,04410193 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01390032 0,04404473 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01390032 0,04398768 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01390032 0,04393077 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01390032 0,04387401 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01390032 0,0438174 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01390032 0,04376094 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01390032 0,04370462 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01390032 0,04364844 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01390032 0,04359241 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01390032 0,04353652 ! histone ubiquitination GO:0016574 9 7 0,000 0,01390032 0,04348078 ! regulation of meiosis GO:0040020 12 7 0,000 0,01390032 0,04342517 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01390032 0,04336971 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01390032 0,0433144 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01390032 0,04325922 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01390032 0,04320418 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01390032 0,04314928 ! transcription termination GO:0006353 14 7 0,000 0,01390032 0,04309453 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01390032 0,04303991 ! anaphase GO:0051322 18 7 0,000 0,01390032 0,04298543 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01390032 0,04293108 ! axonal fasciculation GO:0007413 19 7 0,000 0,01390032 0,04287688 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01390032 0,04282281 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01390032 0,04276887 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01390032 0,04271508 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01390032 0,04266141 ! diuresis GO:0030146 12 7 0,000 0,01390032 0,04260789 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01390032 0,04255449 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01390032 0,04250123 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01390032 0,04244811 ! antibiotic transport GO:0042891 9 7 0,000 0,01390032 0,04239511 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01390032 0,04234225 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01390032 0,04228952 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01390032 0,04223692 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01390032 0,04218446 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01390032 0,04213212 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01390032 0,04207991 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01390032 0,04202783 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01390032 0,04197588 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01390032 0,04192406 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01390032 0,04187236 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01390032 0,0418208 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01390032 0,04176936 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01390032 0,04171804 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01390032 0,04166685 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01390032 0,04161579 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01390032 0,04156485 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01390032 0,04151404 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01390032 0,04146335 ! muscle adaptation GO:0043500 13 7 0,000 0,01390032 0,04141279 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01390032 0,04136235 ! retina homeostasis GO:0001895 12 7 0,000 0,01390032 0,04131203 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01390032 0,04126183 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01390032 0,04121176 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01390032 0,0411618 ! ossification GO:0001503 205 91 1,000 0,01436635 0,0424903 ! bone development GO:0060348 206 92 1,000 0,01466683 0,04332657 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,01497003 0,04416883 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01497003 0,04411555 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01527593 0,04496277 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01558452 0,04581585 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01587047 0,04660042 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01587047 0,04654448 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01587047 0,04648867 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01587047 0,046433 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01587047 0,04637746 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01587047 0,04632205 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01587047 0,04626677 ! male meiosis GO:0007140 9 8 0,000 0,01587047 0,04621162 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01587047 0,04615661 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01587047 0,04610173 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01587047 0,04604697 ! meiotic prophase I GO:0007128 14 8 0,000 0,01587047 0,04599235 ! response to zinc ion GO:0010043 12 8 0,000 0,01587047 0,04593786 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01587047 0,04588349 ! oligopeptide transport GO:0006857 16 8 0,000 0,01587047 0,04582926 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01587047 0,04577515 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01587047 0,04572117 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01587047 0,04566732 ! signal peptide processing GO:0006465 12 8 0,000 0,01587047 0,04561359 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01587047 0,04555999 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01587047 0,04550652 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01587047 0,04545317 ! succinate metabolic process GO:0006105 17 8 0,000 0,01587047 0,04539994 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01587047 0,04534685 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01587047 0,04529387 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01587047 0,04524102 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01587047 0,04518829 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01587047 0,04513568 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01587047 0,0450832 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01587047 0,04503084 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01587047 0,0449786 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01587047 0,04492648 ! reflex GO:0060004 17 8 0,000 0,01587047 0,04487448 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01587047 0,0448226 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01587047 0,04477085 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01587047 0,04471921 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01587047 0,04466769 ! pigment granule organization GO:0048753 17 8 0,000 0,01587047 0,04461629 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01587047 0,044565 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01587047 0,04451384 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01587047 0,04446279 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01587047 0,04441186 ! histidine catabolic process GO:0006548 10 8 0,000 0,01587047 0,04436104 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01587047 0,04431035 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01587047 0,04425976 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01587047 0,0442093 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01587047 0,04415894 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01587047 0,04410871 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01587047 0,04405858 ! melanin metabolic process GO:0006582 17 8 0,000 0,01587047 0,04400857 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01587047 0,04395868 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01587047 0,04390889 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01587047 0,04385922 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01587047 0,04380966 ! macrophage activation GO:0042116 13 8 0,000 0,01587047 0,04376022 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01587047 0,04371088 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01587047 0,04366166 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01587047 0,04361255 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01587047 0,04356354 ! purine salvage GO:0043101 12 8 0,000 0,01587047 0,04351465 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01587047 0,04346587 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01587047 0,04341719 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01587047 0,04336863 ! osteoblast development GO:0002076 17 8 0,000 0,01587047 0,04332017 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01587047 0,04327182 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01587047 0,04322358 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01587047 0,04317545 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01587047 0,04312742 ! response to UV-B GO:0010224 17 8 0,000 0,01587047 0,0430795 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01587047 0,04303169 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01587047 0,04298398 ! intermediate filament organization GO:0045109 12 8 0,000 0,01587047 0,04293638 ! cellular extravasation GO:0045123 13 8 0,000 0,01587047 0,04288889 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01587047 0,04284149 ! response to antibiotic GO:0046677 11 8 0,000 0,01587047 0,04279421 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01587047 0,04274703 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01587047 0,04269995 ! DNA topological change GO:0006265 12 8 0,000 0,01587047 0,04265297 ! response to tropane GO:0014073 15 8 0,000 0,01587047 0,0426061 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01587047 0,04255933 ! melanosome transport GO:0032402 13 8 0,000 0,01587047 0,04251267 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01587047 0,0424661 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01587047 0,04241964 ! mast cell activation GO:0045576 14 8 0,000 0,01587047 0,04237328 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01587047 0,04232702 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01587047 0,04228086 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01587047 0,04223481 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01587047 0,04218885 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01587047 0,04214299 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01587047 0,04209723 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01587047 0,04205158 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01587047 0,04200602 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01587047 0,04196056 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01587047 0,04191519 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01587047 0,04186993 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01587047 0,04182476 ! response to tumor cell GO:0002347 16 8 0,000 0,01587047 0,04177969 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01587047 0,04173472 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01587047 0,04168984 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01587047 0,04164506 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01587047 0,04160038 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01587047 0,04155579 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01587047 0,0415113 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01587047 0,0414669 ! hormone catabolic process GO:0042447 17 8 0,000 0,01587047 0,0414226 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01587047 0,04137839 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01587047 0,04133428 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01587047 0,04129026 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01587047 0,04124633 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01587047 0,0412025 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01587047 0,04115876 ! adult feeding behavior GO:0008343 10 8 0,000 0,01587047 0,04111511 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01587047 0,04107156 ! ATP catabolic process GO:0006200 11 8 0,000 0,01587047 0,0410281 ! blastocyst growth GO:0001832 19 8 0,000 0,01587047 0,04098473 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01587047 0,04094145 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01587047 0,04089826 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01587047 0,04085517 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01587047 0,04081216 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01587047 0,04076925 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01587047 0,04072642 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01587047 0,04068369 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01587047 0,04064104 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01587047 0,04059848 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01587047 0,04055602 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01587047 0,04051364 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01587047 0,04047135 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01587047 0,04042915 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01587047 0,04038703 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01587047 0,04034501 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01587047 0,04030307 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01587047 0,04026122 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01587047 0,04021945 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,01716735 0,04346097 GO:0060538|skeletal muscle organ development, ! axon extension GO:0048675 16 9 0,000 0,01783673 0,04510884 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01783673 0,04506219 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01783673 0,04501564 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01783673 0,04496918 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01783673 0,04492282 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01783673 0,04487656 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01783673 0,04483039 ! reproductive behavior GO:0019098 22 9 0,000 0,01783673 0,04478432 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01783673 0,04473834 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01783673 0,04469245 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01783673 0,04464666 ! UTP metabolic process GO:0046051 10 9 0,000 0,01783673 0,04460096 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01783673 0,04455536 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01783673 0,04450985 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01783673 0,04446443 ! artery development GO:0060840 25 9 0,000 0,01783673 0,0444191 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01783673 0,04437387 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01783673 0,04432873 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01783673 0,04428368 ! equilibrioception GO:0050957 20 9 0,000 0,01783673 0,04423872 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01783673 0,04419385 ! chemosensory behavior GO:0007635 21 9 0,000 0,01783673 0,04414908 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01783673 0,04410439 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01783673 0,0440598 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01783673 0,04401529 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01783673 0,04397088 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01783673 0,04392655 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01783673 0,04388231 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01783673 0,04383817 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01783673 0,04379411 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01783673 0,04375014 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01783673 0,04370626 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01783673 0,04366246 ! protein targeting to ER GO:0045047 25 9 0,000 0,01783673 0,04361876 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01783673 0,04357514 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01783673 0,04353161 ! T cell selection GO:0045058 27 9 0,000 0,01783673 0,04348816 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01783673 0,0434448 ! glycine catabolic process GO:0006546 15 9 0,000 0,01783673 0,04340153 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01783673 0,04335835 ! endosome organization GO:0007032 20 9 0,000 0,01783673 0,04331525 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01783673 0,04327223 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01783673 0,0432293 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01783673 0,04318646 ! mannose metabolic process GO:0006013 13 9 0,000 0,01783673 0,0431437 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01783673 0,04310103 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01783673 0,04305844 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01783673 0,04301593 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01783673 0,04297351 ! receptor clustering GO:0043113 20 9 0,000 0,01783673 0,04293117 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01783673 0,04288892 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01783673 0,04284674 ! retinol metabolic process GO:0042572 20 9 0,000 0,01783673 0,04280465 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01783673 0,04276265 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01783673 0,04272072 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01783673 0,04267888 ! macrophage differentiation GO:0030225 15 9 0,000 0,01783673 0,04263712 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01783673 0,04259544 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01783673 0,04255385 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01783673 0,04251233 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01783673 0,0424709 ! response to amine stimulus GO:0014075 13 9 0,000 0,01783673 0,04242954 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01783673 0,04238827 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01783673 0,04234707 ! erythrocyte development GO:0048821 17 9 0,000 0,01783673 0,04230596 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01783673 0,04226493 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01783673 0,04222397 ! renal water homeostasis GO:0003091 15 9 0,000 0,01783673 0,0421831 ! postreplication repair GO:0006301 25 9 0,000 0,01783673 0,0421423 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01783673 0,04210158 ! icosanoid secretion GO:0032309 15 9 0,000 0,01783673 0,04206094 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01783673 0,04202038 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01783673 0,0419799 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01783673 0,0419395 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01783673 0,04189917 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01783673 0,04185892 ! sterol catabolic process GO:0016127 14 9 0,000 0,01783673 0,04181875 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01783673 0,04177866 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01783673 0,04173864 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01783673 0,0416987 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01783673 0,04165883 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01783673 0,04161904 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01783673 0,04157933 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01783673 0,04153969 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01783673 0,04150013 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01783673 0,04146065 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01783673 0,04142123 ! purine base metabolic process GO:0006144 25 9 0,000 0,01783673 0,0413819 ! pigment granule transport GO:0051904 17 9 0,000 0,01783673 0,04134264 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01783673 0,04130345 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01783673 0,04126434 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01783673 0,0412253 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01783673 0,04118633 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01783673 0,04114744 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01783673 0,04110862 ! mitochondrion localization GO:0051646 18 9 0,000 0,01783673 0,04106988 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,01979912 0,04554544 ! regulation of developmental growth GO:0048638 16 10 0,000 0,01979912 0,0455026 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,01979912 0,04545983 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,01979912 0,04541715 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,01979912 0,04537454 ! associative learning GO:0008306 21 10 0,000 0,01979912 0,04533202 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,01979912 0,04528957 ! phosphate transport GO:0006817 24 10 0,000 0,01979912 0,0452472 ! cell volume homeostasis GO:0006884 17 10 0,000 0,01979912 0,04520492 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,01979912 0,04516271 ! CTP metabolic process GO:0046036 11 10 0,000 0,01979912 0,04512058 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,01979912 0,04507853 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,01979912 0,04503656 ! GTP metabolic process GO:0046039 11 10 0,000 0,01979912 0,04499466 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,01979912 0,04495285 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,01979912 0,04491111 ! social behavior GO:0035176 29 10 0,000 0,01979912 0,04486944 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,01979912 0,04482786 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,01979912 0,04478635 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,01979912 0,04474492 ! androgen metabolic process GO:0008209 17 10 0,000 0,01979912 0,04470357 ! phospholipid efflux GO:0033700 19 10 0,000 0,01979912 0,04466229 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,01979912 0,04462109 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,01979912 0,04457996 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,01979912 0,04453891 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,01979912 0,04449794 ! lung alveolus development GO:0048286 26 10 0,000 0,01979912 0,04445704 ! pathogenesis GO:0009405 17 10 0,000 0,01979912 0,04441622 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,01979912 0,04437547 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,01979912 0,0443348 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,01979912 0,0442942 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,01979912 0,04425367 ! endoderm development GO:0007492 18 10 0,000 0,01979912 0,04421322 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,01979912 0,04417284 ! arginine catabolic process GO:0006527 17 10 0,000 0,01979912 0,04413254 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,01979912 0,04409231 ! proline metabolic process GO:0006560 13 10 0,000 0,01979912 0,04405215 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,01979912 0,04401207 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,01979912 0,04397206 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,01979912 0,04393212 ! V(D)J recombination GO:0033151 34 10 0,000 0,01979912 0,04389225 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,01979912 0,04385246 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,01979912 0,04381274 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,01979912 0,04377309 ! B cell proliferation GO:0042100 19 10 0,000 0,01979912 0,04373351 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,01979912 0,043694 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,01979912 0,04365457 ! multicellular organism growth GO:0035264 19 10 0,000 0,01979912 0,0436152 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,01979912 0,04357591 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,01979912 0,04353669 ! ruffle organization GO:0031529 17 10 0,000 0,01979912 0,04349754 ! epithelial cell development GO:0002064 21 10 0,000 0,01979912 0,04345846 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,01979912 0,04341944 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,01979912 0,0433805 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,01979912 0,04334163 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,01979912 0,04330283 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,01979912 0,0432641 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,01979912 0,04322543 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,01979912 0,04318684 ! motor axon guidance GO:0008045 22 10 0,000 0,01979912 0,04314832 ! copper ion homeostasis GO:0055070 13 10 0,000 0,01979912 0,04310986 ! regulation of bone resorption GO:0045124 25 10 0,000 0,01979912 0,04307147 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,01979912 0,04303315 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,01979912 0,0429949 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,01979912 0,04295672 ! segment specification GO:0007379 15 10 0,000 0,01979912 0,0429186 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,01979912 0,04288055 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,01979912 0,04284257 ! blastoderm segmentation GO:0007350 19 10 0,000 0,01979912 0,04280466 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,01979912 0,04276681 ! response to dsRNA GO:0043331 23 10 0,000 0,01979912 0,04272903 ! DNA ligation GO:0006266 18 10 0,000 0,01979912 0,04269132 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,01979912 0,04265367 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,01979912 0,04261609 ! melanosome localization GO:0032400 16 10 0,000 0,01979912 0,04257858 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,01979912 0,04254113 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,01979912 0,04250374 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,01979912 0,04246643 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,01979912 0,04242918 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,01979912 0,04239199 ! induction of an organ GO:0001759 17 10 0,000 0,01979912 0,04235487 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,01979912 0,04231781 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,01979912 0,04228082 ! protein sumoylation GO:0016925 17 10 0,000 0,01979912 0,0422439 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,01979912 0,04220703 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,01979912 0,04217024 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,01979912 0,0421335 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,01979912 0,04209683 ! salivary gland development GO:0007431 28 10 0,000 0,01979912 0,04206023 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,01979912 0,04202369 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,01979912 0,04198721 ! midbrain development GO:0030901 14 10 0,000 0,01979912 0,04195079 ! musculoskeletal movement GO:0050881 16 10 0,000 0,01979912 0,04191444 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,01979912 0,04187815 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,01979912 0,04184192 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,01979912 0,04180576 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,01979912 0,04176966 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,01979912 0,04173362 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,01979912 0,04169764 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,01979912 0,04166172 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,01979912 0,04162587 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,01979912 0,04159008 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,01979912 0,04155435 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,01979912 0,04151868 ! blastocyst formation GO:0001825 18 10 0,000 0,01979912 0,04148307 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,01979912 0,04144752 ! cerebellar cortex development GO:0021695 16 10 0,000 0,01979912 0,04141204 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,01979912 0,04137661 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,01979912 0,04134125 ! response to nicotine GO:0035094 20 10 0,000 0,01979912 0,04130595 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,01979912 0,0412707 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,01979912 0,04123552 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02175765 0,04527593 ! respiratory burst GO:0045730 17 11 0,000 0,02175765 0,0452374 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02175765 0,04519893 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02175765 0,04516053 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02175765 0,04512219 ! thyroid gland development GO:0030878 26 11 0,000 0,02175765 0,04508392 ! synapsis GO:0007129 14 11 0,000 0,02175765 0,04504571 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02175765 0,04500757 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02175765 0,04496949 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02175765 0,04493148 ! response to pain GO:0048265 27 11 0,000 0,02175765 0,04489353 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02175765 0,04485565 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02175765 0,04481783 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02175765 0,04478007 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02175765 0,04474237 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02175765 0,04470474 ! bone resorption GO:0045453 16 11 0,000 0,02175765 0,04466718 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02175765 0,04462967 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02175765 0,04459223 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02175765 0,04455485 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02175765 0,04451754 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02175765 0,04448029 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02175765 0,04444309 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02175765 0,04440597 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02175765 0,0443689 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02175765 0,04433189 ! UV protection GO:0009650 20 11 0,000 0,02175765 0,04429495 ! adult heart development GO:0007512 16 11 0,000 0,02175765 0,04425807 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02175765 0,04422125 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02175765 0,04418449 ! macroautophagy GO:0016236 19 11 0,000 0,02175765 0,04414779 ! temperature homeostasis GO:0001659 18 11 0,000 0,02175765 0,04411115 ! behavioral fear response GO:0001662 27 11 0,000 0,02175765 0,04407458 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02175765 0,04403806 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02175765 0,04400161 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02175765 0,04396521 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02175765 0,04392888 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02175765 0,0438926 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02175765 0,04385639 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02175765 0,04382023 ! regulation of organ growth GO:0046620 14 11 0,000 0,02175765 0,04378414 ! pigment granule localization GO:0051875 20 11 0,000 0,02175765 0,0437481 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02175765 0,04371212 ! vasoconstriction GO:0042310 20 11 0,000 0,02175765 0,0436762 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02175765 0,04364035 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02175765 0,04360455 ! embryonic axis specification GO:0000578 19 11 0,000 0,02175765 0,0435688 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02175765 0,04353312 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02175765 0,0434975 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02175765 0,04346193 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02175765 0,04342642 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02175765 0,04339097 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02175765 0,04335558 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02175765 0,04332024 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02175765 0,04328497 ! prophase GO:0051324 17 11 0,000 0,02175765 0,04324975 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02175765 0,04321459 ! nucleosome positioning GO:0016584 15 11 0,000 0,02175765 0,04317948 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02175765 0,04314443 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02175765 0,04310944 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02175765 0,04307451 ! apical protein localization GO:0045176 18 11 0,000 0,02175765 0,04303963 ! acid secretion GO:0046717 20 11 0,000 0,02175765 0,04300481 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02175765 0,04297004 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02175765 0,04293533 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02175765 0,04290068 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02175765 0,04286608 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02175765 0,04283154 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02175765 0,04279705 ! cholesterol efflux GO:0033344 21 11 0,000 0,02175765 0,04276262 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02175765 0,04272825 ! oocyte development GO:0048599 20 11 0,000 0,02175765 0,04269393 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02175765 0,04265966 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02175765 0,04262545 ! embryonic gut development GO:0048566 19 11 0,000 0,02175765 0,0425913 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02175765 0,0425572 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02175765 0,04252315 ! activation of innate immune response GO:0002218 16 11 0,000 0,02175765 0,04248916 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02175765 0,04245522 ! lysogeny GO:0030069 22 11 0,000 0,02175765 0,04242134 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02175765 0,04238751 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02175765 0,04235374 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02175765 0,04232002 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02175765 0,04228635 ! nucleus localization GO:0051647 22 11 0,000 0,02175765 0,04225273 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02371232 0,04601207 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02371232 0,04597555 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02371232 0,04593909 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02371232 0,04590269 ! virus-host interaction GO:0019048 30 12 0,000 0,02371232 0,04586635 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02371232 0,04583006 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02371232 0,04579383 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02371232 0,04575766 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02371232 0,04572154 ! hippocampus development GO:0021766 29 12 0,000 0,02371232 0,04568548 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,02371232 0,04564948 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02371232 0,04561354 ! T cell proliferation GO:0042098 32 12 0,000 0,02371232 0,04557765 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02371232 0,04554182 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02371232 0,04550604 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02371232 0,04547032 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02371232 0,04543466 ! drug transport GO:0015893 16 12 0,000 0,02371232 0,04539905 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02371232 0,0453635 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02371232 0,04532801 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02371232 0,04529257 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02371232 0,04525718 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02371232 0,04522185 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02371232 0,04518658 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02371232 0,04515136 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02371232 0,04511619 ! lipid digestion GO:0044241 21 12 0,000 0,02371232 0,04508108 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02371232 0,04504603 ! entry into host cell GO:0030260 34 12 0,000 0,02371232 0,04501103 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02371232 0,04497608 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02371232 0,04494119 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02371232 0,04490635 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02371232 0,04487157 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02371232 0,04483684 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02371232 0,04480216 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02371232 0,04476754 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02371232 0,04473297 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02371232 0,04469845 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02371232 0,04466399 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02371232 0,04462958 ! fucose catabolic process GO:0019317 25 12 0,000 0,02371232 0,04459522 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02371232 0,04456092 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02371232 0,04452667 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02371232 0,04449247 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02371232 0,04445832 ! zymogen activation GO:0031638 18 12 0,000 0,02371232 0,04442423 ! T cell homeostasis GO:0043029 28 12 0,000 0,02371232 0,04439019 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02371232 0,0443562 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02371232 0,04432226 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02371232 0,04428837 ! oocyte differentiation GO:0009994 21 12 0,000 0,02371232 0,04425454 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02371232 0,04422076 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02371232 0,04418703 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02371232 0,04415335 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02371232 0,04411972 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02371232 0,04408614 ! defense response to fungus GO:0050832 15 12 0,000 0,02371232 0,04405262 ! developmental induction GO:0031128 22 12 0,000 0,02371232 0,04401914 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02371232 0,04398572 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02371232 0,04395235 ! response to cold GO:0009409 17 12 0,000 0,02371232 0,04391902 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02371232 0,04388575 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02371232 0,04385253 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02566314 0,04742439 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02566314 0,04738854 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02566314 0,04735275 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02566314 0,04731701 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02566314 0,04728133 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02566314 0,0472457 ! peroxisomal transport GO:0043574 28 13 0,000 0,02566314 0,04721012 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02566314 0,0471746 ! cartilage condensation GO:0001502 22 13 0,000 0,02566314 0,04713913 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02566314 0,04710371 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02566314 0,04706835 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02566314 0,04703304 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02566314 0,04699778 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02566314 0,04696258 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02566314 0,04692742 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02566314 0,04689233 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02566314 0,04685728 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02566314 0,04682228 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02566314 0,04678734 ! methionine metabolic process GO:0006555 31 13 0,000 0,02566314 0,04675245 ! plasma membrane organization GO:0007009 27 13 0,000 0,02566314 0,04671762 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02566314 0,04668283 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02566314 0,04664809 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02566314 0,04661341 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02566314 0,04657878 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02566314 0,0465442 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02566314 0,04650967 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02566314 0,0464752 ! exocrine system development GO:0035272 34 13 0,000 0,02566314 0,04644077 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02566314 0,04640639 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02566314 0,04637207 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02566314 0,0463378 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02566314 0,04630357 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02566314 0,0462694 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02566314 0,04623528 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02566314 0,04620121 ! protein homotetramerization GO:0051289 24 13 0,000 0,02566314 0,04616719 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02566314 0,04613322 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02566314 0,04609929 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02566314 0,04606542 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02566314 0,0460316 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02566314 0,04599783 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02566314 0,04596411 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02566314 0,04593043 ! histone methylation GO:0016571 29 13 0,000 0,02566314 0,04589681 ! chromatin silencing GO:0006342 29 13 0,000 0,02566314 0,04586323 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02566314 0,04582971 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02566314 0,04579623 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02566314 0,0457628 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02566314 0,04572942 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02566314 0,04569609 ! spleen development GO:0048536 24 13 0,000 0,02566314 0,04566281 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02566314 0,04562958 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02566314 0,04559639 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02566314 0,04556326 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02566314 0,04553017 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02566314 0,04549713 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02566314 0,04546413 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02566314 0,04543119 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02566314 0,04539829 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02566314 0,04536544 ! insulin secretion GO:0030073 24 13 0,000 0,02566314 0,04533264 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02566314 0,04529988 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02566314 0,04526718 ! acrosome reaction GO:0007340 19 13 0,000 0,02566314 0,04523452 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02566314 0,0452019 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02566314 0,04516934 ! rRNA transcription GO:0009303 28 14 0,000 0,02761011 0,04856119 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02761011 0,04852626 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02761011 0,04849137 ! water transport GO:0006833 21 14 0,000 0,02761011 0,04845653 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02761011 0,04842175 ! non-recombinational repair GO:0000726 29 14 0,000 0,02761011 0,04838701 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02761011 0,04835233 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02761011 0,04831769 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02761011 0,0482831 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02761011 0,04824857 ! palate development GO:0060021 32 14 0,000 0,02761011 0,04821408 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02761011 0,04817964 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02761011 0,04814525 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02761011 0,04811091 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02761011 0,04807662 ! arginine metabolic process GO:0006525 21 14 0,000 0,02761011 0,04804238 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02761011 0,04800818 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02761011 0,04797404 ! regulation of heart rate GO:0002027 25 14 0,000 0,02761011 0,04793994 ! fear response GO:0042596 34 14 0,000 0,02761011 0,04790589 ! organic alcohol transport GO:0015850 29 14 0,000 0,02761011 0,04787189 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02761011 0,04783794 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02761011 0,04780404 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02761011 0,04777018 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02761011 0,04773637 ! bone mineralization GO:0030282 18 14 0,000 0,02761011 0,04770261 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02761011 0,0476689 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02761011 0,04763524 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02761011 0,04760162 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02761011 0,04756805 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02761011 0,04753453 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02761011 0,04750105 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02761011 0,04746763 ! ribosome assembly GO:0042255 18 14 0,000 0,02761011 0,04743424 ! cerebellum development GO:0021549 23 14 0,000 0,02761011 0,04740091 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02761011 0,04736762 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02761011 0,04733438 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02761011 0,04730119 ! response to gamma radiation GO:0010332 30 14 0,000 0,02761011 0,04726804 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02761011 0,04723494 ! NADP metabolic process GO:0006739 24 14 0,000 0,02761011 0,04720189 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02761011 0,04716888 ! oxygen transport GO:0015671 22 14 0,000 0,02761011 0,04713592 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02761011 0,047103 ! male genitalia development GO:0030539 26 14 0,000 0,02761011 0,04707013 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02761011 0,04703731 ! regulation of axon extension GO:0030516 43 14 0,000 0,02761011 0,04700453 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02761011 0,04697179 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02761011 0,04693911 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02955325 0,05020764 ! lactation GO:0007595 30 15 0,000 0,02955325 0,05017275 ! reproductive cellular process GO:0048610 22 15 0,000 0,02955325 0,0501379 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02955325 0,05010311 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,02955325 0,05006836 ! superoxide anion generation GO:0042554 22 15 0,000 0,02955325 0,05003367 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,02955325 0,04999902 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,02955325 0,04996442 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,02955325 0,04992986 ! copper ion transport GO:0006825 22 15 0,000 0,02955325 0,04989536 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,02955325 0,0498609 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,02955325 0,04982649 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,02955325 0,04979212 ! sulfate transport GO:0008272 27 15 0,000 0,02955325 0,04975781 ! response to cAMP GO:0051591 25 15 0,000 0,02955325 0,04972354 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,02955325 0,04968932 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,02955325 0,04965515 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,02955325 0,04962102 ! response to hexose stimulus GO:0009746 25 15 0,000 0,02955325 0,04958694 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,02955325 0,0495529 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,02955325 0,04951892 ! vesicle coating GO:0006901 38 15 0,000 0,02955325 0,04948498 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,02955325 0,04945108 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,02955325 0,04941724 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,02955325 0,04938343 ! regulation of exocytosis GO:0017157 26 15 0,000 0,02955325 0,04934968 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,02955325 0,04931597 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,02955325 0,04928231 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,02955325 0,04924869 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,02955325 0,04921512 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,02955325 0,04918159 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,02955325 0,04914812 ! histone deacetylation GO:0016575 24 15 0,000 0,02955325 0,04911468 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02955325 0,04908129 ! water homeostasis GO:0030104 28 15 0,000 0,02955325 0,04904795 ! cofactor transport GO:0051181 30 15 0,000 0,02955325 0,04901465 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02955325 0,0489814 ! muscle maintenance GO:0046716 26 15 0,000 0,02955325 0,04894819 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,02955325 0,04891503 ! intestinal absorption GO:0050892 31 15 0,000 0,02955325 0,04888191 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02955325 0,04884884 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,02955325 0,04881581 ! heme biosynthetic process GO:0006783 33 15 0,000 0,02955325 0,04878283 ! cell killing GO:0001906 32 15 0,000 0,02955325 0,04874989 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,02955325 0,04871699 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,02955325 0,04868414 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,02955325 0,04865134 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,02955325 0,04861857 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,02955325 0,04858586 ! actin filament polymerization GO:0030041 27 15 0,000 0,02955325 0,04855318 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,02955325 0,04852055 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03149256 0,05166979 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03149256 0,05163511 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03149256 0,05160048 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03149256 0,05156589 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03149256 0,05153136 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03149256 0,05149686 ! bone remodeling GO:0046849 28 16 0,000 0,03149256 0,05146242 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03149256 0,05142802 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03149256 0,05139366 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03149256 0,05135935 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03149256 0,05132509 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03149256 0,05129088 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03149256 0,0512567 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03149256 0,05122258 ! startle response GO:0001964 28 16 0,000 0,03149256 0,0511885 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03149256 0,05115446 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03149256 0,05112047 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03149256 0,05108653 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03149256 0,05105263 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03149256 0,05101878 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03149256 0,05098497 ! pituitary gland development GO:0021983 30 16 0,000 0,03149256 0,0509512 ! response to osmotic stress GO:0006970 27 16 0,000 0,03149256 0,05091748 ! lysosomal transport GO:0007041 31 16 0,000 0,03149256 0,05088381 ! fructose metabolic process GO:0006000 25 16 0,000 0,03149256 0,05085017 ! L-amino acid transport GO:0015807 33 16 0,000 0,03149256 0,05081659 ! stem cell development GO:0048864 46 16 0,000 0,03149256 0,05078305 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03149256 0,05074955 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03149256 0,05071609 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03149256 0,05068268 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03149256 0,05064932 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03149256 0,050616 ! axon cargo transport GO:0008088 46 16 0,000 0,03149256 0,05058272 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03149256 0,05054948 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03149256 0,05051629 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,03149256 0,05048315 ! DNA replication initiation GO:0006270 28 16 0,000 0,03149256 0,05045004 ! neuron recognition GO:0008038 40 16 0,000 0,03149256 0,05041698 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03149256 0,05038396 ! tissue regeneration GO:0042246 27 16 0,000 0,03149256 0,05035099 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03149256 0,05031806 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03149256 0,05028517 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03149256 0,05025233 ! biomineral formation GO:0031214 22 16 0,000 0,03149256 0,05021953 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03149256 0,05018677 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03149256 0,05015405 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03149256 0,05012138 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03149256 0,05008875 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03149256 0,05005616 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03149256 0,05002361 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03149256 0,04999111 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03149256 0,04995865 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03149256 0,04992623 ! peptide hormone processing GO:0016486 27 16 0,000 0,03149256 0,04989385 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03342804 0,05292593 ! metencephalon development GO:0022037 32 17 0,000 0,03342804 0,05289165 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03342804 0,05285742 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03342804 0,05282323 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03342804 0,05278908 ! signal complex assembly GO:0007172 47 17 0,000 0,03342804 0,05275498 ! filopodium assembly GO:0046847 42 17 0,000 0,03342804 0,05272092 ! endothelial cell migration GO:0043542 31 17 0,000 0,03342804 0,05268691 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03342804 0,05265294 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03342804 0,05261902 ! glial cell development GO:0021782 28 17 0,000 0,03342804 0,05258513 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03342804 0,05255129 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03342804 0,0525175 ! myoblast differentiation GO:0045445 50 17 0,000 0,03342804 0,05248375 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03342804 0,05245004 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03342804 0,05241637 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03342804 0,05238275 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03342804 0,05234917 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03342804 0,05231564 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03342804 0,05228215 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03342804 0,0522487 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03342804 0,05221529 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03342804 0,05218192 ! membrane budding GO:0006900 42 17 0,000 0,03342804 0,0521486 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03342804 0,05211532 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03342804 0,05208209 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03342804 0,05204889 ! genitalia development GO:0048806 32 17 0,000 0,03342804 0,05201574 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03342804 0,05198263 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03342804 0,05194956 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03342804 0,05191654 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03342804 0,05188355 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03342804 0,05185061 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03342804 0,05181771 ! steroid catabolic process GO:0006706 34 17 0,000 0,03342804 0,05178485 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03342804 0,05175204 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03342804 0,05171926 ! gas transport GO:0015669 26 17 0,000 0,03342804 0,05168653 ! organic cation transport GO:0015695 32 17 0,000 0,03342804 0,05165383 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03342804 0,05162118 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03342804 0,05158857 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03342804 0,051556 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03535972 0,05450082 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03535972 0,05446645 ! limbic system development GO:0021761 40 18 0,000 0,03535972 0,05443213 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03535972 0,05439785 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03535972 0,05436362 ! adult walking behavior GO:0007628 36 18 0,000 0,03535972 0,05432943 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03535972 0,05429528 ! heart looping GO:0001947 34 18 0,000 0,03535972 0,05426118 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03535972 0,05422711 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03535972 0,05419309 ! centrosome cycle GO:0007098 26 18 0,000 0,03535972 0,05415912 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03535972 0,05412518 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03535972 0,05409129 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03535972 0,05405744 ! glycine metabolic process GO:0006544 30 18 0,000 0,03535972 0,05402364 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03535972 0,05398987 ! response to retinoic acid GO:0032526 31 18 0,000 0,03535972 0,05395615 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03535972 0,05392247 ! DNA integration GO:0015074 32 18 0,000 0,03535972 0,05388883 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03535972 0,05385523 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03535972 0,05382168 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03535972 0,05378817 ! neural crest cell migration GO:0001755 41 18 0,000 0,03535972 0,05375469 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03535972 0,05372126 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03535972 0,05368788 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03535972 0,05365453 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03535972 0,05362122 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03535972 0,05358796 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03535972 0,05355474 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03535972 0,05352156 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03535972 0,05348842 ! detection of bacterium GO:0016045 22 18 0,000 0,03535972 0,05345532 ! defense response to virus GO:0051607 43 18 0,000 0,03535972 0,05342226 ! microspike assembly GO:0030035 46 18 0,000 0,03535972 0,05338924 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03535972 0,05335627 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03535972 0,05332333 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03728759 0,05619591 ! positive regulation of translation GO:0045727 31 19 0,000 0,03728759 0,05616127 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03728759 0,05612666 ! neuron maturation GO:0042551 46 19 0,000 0,03728759 0,0560921 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03728759 0,05605759 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03728759 0,05602311 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03728759 0,05598868 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03728759 0,05595429 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03728759 0,05591994 ! inositol metabolic process GO:0006020 33 19 0,000 0,03728759 0,05588563 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03728759 0,05585136 ! memory GO:0007613 34 19 0,000 0,03728759 0,05581714 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03728759 0,05578296 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03728759 0,05574882 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03728759 0,05571473 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03728759 0,05568067 ! cerebral cortex development GO:0021987 40 19 0,000 0,03728759 0,05564666 ! pigmentation during development GO:0048066 42 19 0,000 0,03728759 0,05561268 ! response to vitamin A GO:0033189 32 19 0,000 0,03728759 0,05557875 ! heme metabolic process GO:0042168 40 19 0,000 0,03728759 0,05554486 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03728759 0,05551102 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03728759 0,05547721 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03728759 0,05544344 ! response to fungus GO:0009620 26 19 0,000 0,03728759 0,05540972 ! peptide cross-linking GO:0018149 39 19 0,000 0,03728759 0,05537603 ! protein export from nucleus GO:0006611 40 19 0,000 0,03728759 0,05534239 ! heart process GO:0003015 32 19 0,000 0,03728759 0,05530879 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03728759 0,05527523 ! visual learning GO:0008542 38 19 0,000 0,03728759 0,05524171 ! cellular pigmentation GO:0033059 37 19 0,000 0,03728759 0,05520823 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03728759 0,05517479 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03728759 0,05514139 ! vitamin transport GO:0051180 31 19 0,000 0,03728759 0,05510803 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03728759 0,05507471 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03728759 0,05504144 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03728759 0,0550082 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03728759 0,054975 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03728759 0,05494184 ! cilium assembly GO:0042384 38 19 0,000 0,03728759 0,05490873 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03728759 0,05487565 ! protein secretion GO:0009306 45 20 0,000 0,03921166 0,05767253 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,03921166 0,05763783 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,03921166 0,05760317 ! positive regulation of ossification GO:0045778 50 20 0,000 0,03921166 0,05756856 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,03921166 0,05753398 ! skin development GO:0043588 42 20 0,000 0,03921166 0,05749945 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,03921166 0,05746495 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,03921166 0,0574305 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,03921166 0,05739609 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,03921166 0,05736172 ! response to vitamin GO:0033273 36 20 0,000 0,03921166 0,0573274 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,03921166 0,05729311 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,03921166 0,05725886 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,03921166 0,05722466 ! bile acid metabolic process GO:0008206 34 20 0,000 0,03921166 0,05719049 ! response to alkaloid GO:0043279 38 20 0,000 0,03921166 0,05715637 ! retinoid metabolic process GO:0001523 34 20 0,000 0,03921166 0,05712229 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,03921166 0,05708825 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,03921166 0,05705425 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,03921166 0,05702028 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,03921166 0,05698636 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,03921166 0,05695248 ! body fluid secretion GO:0007589 33 20 0,000 0,03921166 0,05691864 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,03921166 0,05688484 ! peptide secretion GO:0002790 38 20 0,000 0,03921166 0,05685109 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,03921166 0,05681737 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,03921166 0,05678369 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,03921166 0,05675005 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,03921166 0,05671645 ! cell-cell junction organization GO:0045216 43 20 0,000 0,03921166 0,05668289 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,03921166 0,05664937 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,03921166 0,05661589 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,03921166 0,05658244 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,03921166 0,05654904 ! regulation of glucose import GO:0046324 30 20 0,000 0,03921166 0,05651568 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,03921166 0,05648236 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,03921166 0,05644907 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,03921166 0,05641583 ! negative regulation of translation GO:0017148 32 20 0,000 0,03921166 0,05638262 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,03921166 0,05634946 ! regulation of cell killing GO:0031341 46 21 0,000 0,04113194 0,05907426 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04113194 0,05903955 ! hormone secretion GO:0046879 39 21 0,000 0,04113194 0,05900488 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04113194 0,05897026 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04113194 0,05893567 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04113194 0,05890112 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04113194 0,05886662 ! ovarian follicle development GO:0001541 39 21 0,000 0,04113194 0,05883215 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04113194 0,05879773 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04113194 0,05876334 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04113194 0,058729 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04113194 0,0586947 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04113194 0,05866043 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04113194 0,05862621 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04113194 0,05859202 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04113194 0,05855788 ! diencephalon development GO:0021536 36 21 0,000 0,04113194 0,05852377 ! collagen fibril organization GO:0030199 62 21 0,000 0,04113194 0,05848971 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04113194 0,05845568 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04113194 0,0584217 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04113194 0,05838775 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04113194 0,05835384 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04113194 0,05831998 ! collagen catabolic process GO:0030574 29 21 0,000 0,04113194 0,05828615 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04113194 0,05825236 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04113194 0,05821861 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04113194 0,0581849 ! actin filament-based movement GO:0030048 47 21 0,000 0,04113194 0,05815123 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04113194 0,05811759 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04304843 0,06079036 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04304843 0,06075524 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04304843 0,06072016 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04304843 0,06068512 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04304843 0,06065012 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 59 22 0,000 0,04304843 0,06061517 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04304843 0,06058025 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04304843 0,06054537 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04304843 0,06051054 ! vacuolar transport GO:0007034 41 22 0,000 0,04304843 0,06047574 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04304843 0,06044099 ! fucose metabolic process GO:0006004 44 22 0,000 0,04304843 0,06040627 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04304843 0,06037159 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04304843 0,06033696 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04304843 0,06030236 ! ureteric bud development GO:0001657 50 22 0,000 0,04304843 0,0602678 ! cell aging GO:0007569 48 22 0,000 0,04304843 0,06023328 ! stem cell differentiation GO:0048863 57 22 0,000 0,04304843 0,06019881 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04304843 0,06016437 ! cytolysis GO:0019835 27 22 0,000 0,04304843 0,06012997 ! renal system process GO:0003014 42 22 0,000 0,04304843 0,06009561 ! vasodilation GO:0042311 40 22 0,000 0,04304843 0,06006129 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04304843 0,06002701 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04304843 0,05999276 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04304843 0,05995856 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04304843 0,0599244 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,04304843 0,05989027 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04304843 0,05985618 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04304843 0,05982214 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04304843 0,05978813 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04304843 0,05975416 ! sarcomere organization GO:0045214 32 22 0,000 0,04304843 0,05972022 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04304843 0,05968633 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04304843 0,05965248 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04304843 0,05961866 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04304843 0,05958488 ! gut development GO:0048565 44 22 0,000 0,04304843 0,05955114 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04304843 0,05951744 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04304843 0,05948378 ! protein stabilization GO:0050821 41 22 0,000 0,04304843 0,05945015 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04496115 0,06205654 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04496115 0,0620215 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04496115 0,0619865 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04496115 0,06195154 ! gluconeogenesis GO:0006094 38 23 0,000 0,04496115 0,06191662 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04496115 0,06188174 ! viral genome replication GO:0019079 44 23 0,000 0,04496115 0,06184689 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,04496115 0,06181209 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04496115 0,06177733 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04496115 0,0617426 ! regeneration GO:0031099 42 23 0,000 0,04496115 0,06170791 ! axis specification GO:0009798 43 23 0,000 0,04496115 0,06167326 ! visual behavior GO:0007632 46 23 0,000 0,04496115 0,06163866 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04496115 0,06160409 ! response to ethanol GO:0045471 47 23 0,000 0,04496115 0,06156955 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04496115 0,06153506 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04496115 0,06150061 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04496115 0,06146619 ! peroxisome organization GO:0007031 43 23 0,000 0,04496115 0,06143181 ! lysosome organization GO:0007040 47 23 0,000 0,04496115 0,06139748 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04496115 0,06136318 ! vesicle targeting GO:0006903 49 23 0,000 0,04496115 0,06132891 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04496115 0,06129469 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04496115 0,0612605 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04496115 0,06122636 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04496115 0,06119225 ! DNA modification GO:0006304 36 23 0,000 0,04496115 0,06115818 ! fatty acid transport GO:0015908 47 23 0,000 0,04496115 0,06112414 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04496115 0,06109015 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04496115 0,06105619 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04496115 0,06102227 ! hormone transport GO:0009914 41 23 0,000 0,04496115 0,06098839 ! cell-cell recognition GO:0009988 28 23 0,000 0,04496115 0,06095454 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04496115 0,06092073 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04496115 0,06088696 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04496115 0,06085323 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0468701 0,0634018 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0468701 0,06336671 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0468701 0,06333166 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0468701 0,06329665 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0468701 0,06326168 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0468701 0,06322675 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0468701 0,06319186 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0468701 0,063157 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0468701 0,06312219 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0468701 0,06308741 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0468701 0,06305267 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0468701 0,06301797 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0468701 0,0629833 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0468701 0,06294868 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0468701 0,06291409 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0468701 0,06287954 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0468701 0,06284503 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0468701 0,06281056 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0468701 0,06277612 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0468701 0,06274172 ! pallium development GO:0021543 56 24 0,000 0,0468701 0,06270736 ! oogenesis GO:0048477 44 24 0,000 0,0468701 0,06267304 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0468701 0,06263876 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0468701 0,06260451 ! platelet activation GO:0030168 41 24 0,000 0,0468701 0,0625703 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0468701 0,06253613 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0468701 0,06250199 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0468701 0,06246789 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0468701 0,06243383 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0468701 0,06239981 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0468701 0,06236582 ! regulation of amine transport GO:0051952 41 24 0,000 0,0468701 0,06233187 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,04877528 0,06483026 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,04877528 0,06479501 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,04877528 0,06475979 ! leukocyte adhesion GO:0007159 55 25 0,000 0,04877528 0,06472461 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,04877528 0,06468948 ! phototransduction GO:0007602 37 25 0,000 0,04877528 0,06465438 ! keratinization GO:0031424 37 25 0,000 0,04877528 0,06461931 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,04877528 0,06458429 ! vacuole organization GO:0007033 49 25 0,000 0,04877528 0,0645493 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,04877528 0,06451436 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,04877528 0,06447945 ! receptor metabolic process GO:0043112 53 25 0,000 0,04877528 0,06444457 ! chromosome condensation GO:0030261 48 25 0,000 0,04877528 0,06440974 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,04877528 0,06437494 ! regulation of behavior GO:0050795 48 25 0,000 0,04877528 0,06434018 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,04877528 0,06430546 ! interaction with host GO:0051701 66 25 0,000 0,04877528 0,06427077 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,04877528 0,06423613 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,04877528 0,06420152 ! immunoglobulin production GO:0002377 62 25 0,000 0,04877528 0,06416694 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,04877528 0,06413241 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,04877528 0,06409791 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,04877528 0,06406345 ! liver development GO:0001889 55 25 0,000 0,04877528 0,06402903 ! protein tetramerization GO:0051262 57 25 0,000 0,04877528 0,06399464 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05067671 0,06645368 ! myelination GO:0042552 50 26 0,000 0,05067671 0,06641803 ! initiation of viral infection GO:0019059 60 26 0,000 0,05067671 0,06638242 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05067671 0,06634685 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05067671 0,06631131 ! molting cycle process GO:0022404 52 26 0,000 0,05067671 0,06627581 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05067671 0,06624035 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,05067671 0,06620493 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05067671 0,06616954 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05067671 0,0661342 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05067671 0,06609889 ! digestive system process GO:0022600 49 26 0,000 0,05067671 0,06606361 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05067671 0,06602838 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,05067671 0,06599318 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05067671 0,06595803 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05067671 0,0659229 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05067671 0,06588782 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05067671 0,06585277 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05067671 0,06581776 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05067671 0,06578279 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05067671 0,06574786 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05067671 0,06571296 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05067671 0,0656781 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05067671 0,06564327 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05067671 0,06560849 ! blastocyst development GO:0001824 50 26 0,000 0,05067671 0,06557374 ! telomere organization GO:0032200 46 26 0,000 0,05067671 0,06553902 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05067671 0,06550435 ! neural tube closure GO:0001843 58 26 0,000 0,05067671 0,06546971 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05067671 0,0654351 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05067671 0,06540054 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05067671 0,06536601 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,0525744 0,06777797 ! embryonic pattern specification GO:0009880 49 27 0,000 0,0525744 0,06774222 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,0525744 0,06770651 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,0525744 0,06767084 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,0525744 0,06763521 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,0525744 0,06759961 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,0525744 0,06756405 ! iron ion transport GO:0006826 65 27 0,000 0,0525744 0,06752853 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,0525744 0,06749304 ! superoxide metabolic process GO:0006801 41 27 0,000 0,0525744 0,06745759 ! tube lumen formation GO:0035148 59 27 0,000 0,0525744 0,06742218 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,0525744 0,06738681 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,0525744 0,06735147 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,0525744 0,06731617 ! response to toxin GO:0009636 49 27 0,000 0,0525744 0,06728091 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,0525744 0,06724568 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,0525744 0,0672105 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,0525744 0,06717534 ! leukocyte proliferation GO:0070661 59 27 0,000 0,0525744 0,06714023 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,0525744 0,06710515 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05446834 0,06948625 ! circadian rhythm GO:0007623 56 28 0,000 0,05446834 0,06944998 ! dendrite development GO:0016358 67 28 0,000 0,05446834 0,06941375 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05446834 0,06937756 ! fat cell differentiation GO:0045444 57 28 0,000 0,05446834 0,06934141 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05446834 0,06930529 ! sperm motility GO:0030317 37 28 0,000 0,05446834 0,06926922 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05446834 0,06923318 ! base-excision repair GO:0006284 41 28 0,000 0,05446834 0,06919717 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05446834 0,06916121 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05446834 0,06912528 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05446834 0,06908939 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05446834 0,06905354 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05446834 0,06901772 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05446834 0,06898194 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,05446834 0,0689462 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05446834 0,06891049 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05446834 0,06887483 ! lipid oxidation GO:0034440 48 28 0,000 0,05446834 0,06883919 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05446834 0,0688036 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05446834 0,06876804 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05635855 0,07111774 ! translational initiation GO:0006413 66 29 0,000 0,05635855 0,07108103 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05635855 0,07104435 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05635855 0,07100771 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05635855 0,07097111 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,05635855 0,07093454 ! autophagy GO:0006914 47 29 0,000 0,05635855 0,07089802 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05635855 0,07086153 ! primary neural tube formation GO:0014020 61 29 0,000 0,05635855 0,07082508 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05635855 0,07078866 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05635855 0,07075229 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05635855 0,07071595 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,05635855 0,07067965 ! somitogenesis GO:0001756 52 29 0,000 0,05635855 0,07064338 ! synaptogenesis GO:0007416 46 29 0,000 0,05635855 0,07060715 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05635855 0,07057096 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05635855 0,07053481 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,05824504 0,07285849 ! phenol metabolic process GO:0018958 56 30 0,000 0,05824504 0,0728212 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,05824504 0,07278396 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,05824504 0,07274675 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,05824504 0,07270957 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,05824504 0,07267244 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,05824504 0,07263534 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,05824504 0,07259828 ! acute-phase response GO:0006953 50 30 0,000 0,05824504 0,07256126 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,05824504 0,07252428 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,05824504 0,07248733 ! myofibril assembly GO:0030239 50 30 0,000 0,05824504 0,07245042 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,05824504 0,07241355 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,05824504 0,07237672 ! cell fate determination GO:0001709 64 30 0,000 0,05824504 0,07233993 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,05824504 0,07230317 ! phospholipid transport GO:0015914 65 30 0,000 0,05824504 0,07226645 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,05824504 0,07222976 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,05824504 0,07219312 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,05824504 0,07215651 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,05824504 0,07211994 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,05824504 0,0720834 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06012781 0,07437582 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06012781 0,07433818 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06012781 0,07430057 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06012781 0,07426301 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06012781 0,07422548 ! ovulation cycle process GO:0022602 55 31 0,000 0,06012781 0,074188 ! peptide transport GO:0015833 60 31 0,000 0,06012781 0,07415055 ! male gonad development GO:0008584 56 31 0,000 0,06012781 0,07411314 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06012781 0,07407576 ! detection of light stimulus GO:0009583 44 31 0,000 0,06012781 0,07403842 ! natural killer cell activation GO:0030101 50 31 0,000 0,06012781 0,07400113 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06012781 0,07396386 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06012781 0,07392664 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06012781 0,07388945 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06012781 0,07385231 ! eye morphogenesis GO:0048592 65 31 0,000 0,06012781 0,07381519 ! response to heat GO:0009408 54 31 0,000 0,06012781 0,07377812 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06012781 0,07374108 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06200686 0,07600741 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06200686 0,07596929 ! collagen metabolic process GO:0032963 49 32 0,000 0,06200686 0,07593121 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06200686 0,07589317 ! spindle organization GO:0007051 50 32 0,000 0,06200686 0,07585517 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06200686 0,0758172 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06200686 0,07577927 ! metanephros development GO:0001656 81 32 0,000 0,06200686 0,07574138 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06200686 0,07570353 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,06200686 0,07566572 ! muscle cell development GO:0055001 52 32 0,000 0,06200686 0,07562794 ! mesoderm formation GO:0001707 73 32 0,000 0,06200686 0,0755902 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06200686 0,0755525 ! ovulation cycle GO:0042698 57 32 0,000 0,06200686 0,07551484 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06200686 0,07547721 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06200686 0,07543963 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06200686 0,07540208 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,06200686 0,07536456 ! gene silencing GO:0016458 71 32 0,000 0,06200686 0,07532709 ! regulation of pH GO:0006885 56 33 0,000 0,06388222 0,07756673 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06388222 0,07752819 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06388222 0,0774897 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06388222 0,07745124 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06388222 0,07741282 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06388222 0,07737444 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06388222 0,0773361 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06388222 0,0772978 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06388222 0,07725953 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06388222 0,0772213 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06388222 0,07718311 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06388222 0,07714496 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06388222 0,07710685 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06575387 0,07932677 ! post-embryonic development GO:0009791 76 34 0,000 0,06575387 0,07928762 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06575387 0,0792485 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06575387 0,07920942 ! spliceosome assembly GO:0000245 75 34 0,000 0,06575387 0,07917038 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06575387 0,07913138 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,06575387 0,07909242 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06575387 0,0790535 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06575387 0,07901461 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,06575387 0,07897577 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06762184 0,08117944 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06762184 0,08113956 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06762184 0,08109973 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06762184 0,08105994 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06762184 0,08102018 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06762184 0,08098047 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06762184 0,08094079 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06762184 0,08090115 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,06762184 0,08086155 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06762184 0,08082199 ! telencephalon development GO:0021537 81 35 0,000 0,06762184 0,08078247 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06762184 0,08074299 ! placenta development GO:0001890 53 35 0,000 0,06762184 0,08070354 ! vesicle localization GO:0051648 70 35 0,000 0,06762184 0,08066414 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,06948612 0,08284753 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,06948612 0,08280712 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,06948612 0,08276675 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,06948612 0,08272641 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,06948612 0,08268612 ! positive regulation of cell development GO:0010720 85 36 0,000 0,06948612 0,08264586 ! protein targeting to membrane GO:0006612 75 36 0,000 0,06948612 0,08260564 ! regulation of proteolysis GO:0030162 77 36 0,000 0,06948612 0,08256546 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,06948612 0,08252533 ! aerobic respiration GO:0009060 56 36 0,000 0,06948612 0,08248523 ! cytokine production GO:0001816 68 36 0,000 0,06948612 0,08244517 ! embryonic organ development GO:0048568 67 36 0,000 0,06948612 0,08240514 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,06948612 0,08236516 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,06948612 0,08232522 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07134673 0,08448864 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07134673 0,0844477 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07134673 0,08440681 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07134673 0,08436595 ! odontogenesis GO:0042476 74 37 0,000 0,07134673 0,08432514 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07134673 0,08428436 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07134673 0,08424363 ! female gonad development GO:0008585 71 37 0,000 0,07134673 0,08420293 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07134673 0,08416227 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07134673 0,08412165 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,07320367 0,08626945 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07320367 0,08622785 ! meiosis I GO:0007127 74 38 0,000 0,07320367 0,0861863 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07320367 0,08614478 ! organic anion transport GO:0015711 82 38 0,000 0,07320367 0,08610331 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07320367 0,08606187 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07320367 0,08602048 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07320367 0,08597912 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07320367 0,0859378 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07320367 0,08589653 ! regulation of protein stability GO:0031647 77 38 0,000 0,07320367 0,08585529 ! spermatid development GO:0007286 69 38 0,000 0,07320367 0,08581409 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07320367 0,08577293 ! pigment metabolic process GO:0042440 87 38 0,000 0,07320367 0,08573182 ! neural tube formation GO:0001841 79 38 0,000 0,07320367 0,08569074 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,07505695 0,08781807 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,07505695 0,08777603 ! negative regulation of binding GO:0051100 71 39 0,000 0,07505695 0,08773403 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,07505695 0,08769208 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,07505695 0,08765016 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,07505695 0,08760828 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,07505695 0,08756644 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,07505695 0,08752464 ! glucan metabolic process GO:0044042 64 39 0,000 0,07505695 0,08748289 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07690658 0,08959598 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07690658 0,08955327 ! learning GO:0007612 82 40 0,000 0,07690658 0,08951061 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07690658 0,08946798 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07690658 0,0894254 ! mismatch repair GO:0006298 58 40 0,000 0,07690658 0,08938286 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07690658 0,08934035 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07690658 0,08929789 ! RNA export from nucleus GO:0006405 61 41 0,000 0,07875255 0,09139786 ! mRNA catabolic process GO:0006402 79 41 0,000 0,07875255 0,09135446 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,07875255 0,0913111 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,07875255 0,09126779 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,07875255 0,09122451 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,07875255 0,09118128 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,07875255 0,09113808 ! feeding behavior GO:0007631 69 41 0,000 0,07875255 0,09109493 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,07875255 0,09105182 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,07875255 0,09100875 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,07875255 0,09096572 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,07875255 0,09092273 ! spermatid differentiation GO:0048515 73 41 0,000 0,07875255 0,09087978 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,07875255 0,09083687 ! RNA modification GO:0009451 64 41 0,000 0,07875255 0,090794 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,08059489 0,09287421 ! ear morphogenesis GO:0042471 64 42 0,000 0,08059489 0,09283042 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,08059489 0,09278668 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,08059489 0,09274297 ! T cell differentiation GO:0030217 93 42 0,000 0,08059489 0,09269931 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,08059489 0,09265568 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,08059489 0,0926121 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,08059489 0,09256856 ! regulation of protein secretion GO:0050708 77 42 0,000 0,08059489 0,09252506 ! cytokinesis GO:0000910 84 42 0,000 0,08059489 0,0924816 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,08059489 0,09243818 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,0824336 0,09450272 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,0824336 0,09445839 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,0824336 0,0944141 ! regulation of tube size GO:0035150 76 43 0,000 0,0824336 0,09436986 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,0824336 0,09432566 ! glucose transport GO:0015758 66 43 0,000 0,0824336 0,0942815 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,0824336 0,09423738 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,0824336 0,0941933 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,0824336 0,09414927 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,0824336 0,09410527 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,0824336 0,09406132 ! segmentation GO:0035282 78 43 0,000 0,0824336 0,09401741 ! ion transmembrane transport GO:0034220 79 43 0,000 0,0824336 0,09397354 ! neuron migration GO:0001764 85 43 0,000 0,0824336 0,0939297 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,08426868 0,09597594 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,08426868 0,09593122 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,08426868 0,09588653 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,08426868 0,09584189 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,08426868 0,0957973 ! hexose transport GO:0008645 68 44 0,000 0,08426868 0,09575274 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,08426868 0,09570822 ! striated muscle contraction GO:0006941 85 44 0,000 0,08426868 0,09566375 ! phagocytosis GO:0006909 105 44 0,000 0,08426868 0,09561932 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,08426868 0,09557493 ! double-strand break repair GO:0006302 85 44 0,000 0,08426868 0,09553057 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,08610014 0,09756153 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,08610014 0,0975163 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,08610014 0,09747111 ! biopolymer methylation GO:0043414 91 45 0,000 0,08610014 0,09742596 ! B cell differentiation GO:0030183 124 45 0,000 0,08610014 0,09738086 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,08610014 0,09733579 ! female gamete generation GO:0007292 71 45 0,000 0,08610014 0,09729077 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,08610014 0,09724579 ! polyol metabolic process GO:0019751 77 45 0,000 0,08610014 0,09720086 ! developmental growth GO:0048589 88 45 0,000 0,08610014 0,09715596 ! maintenance of location in cell GO:0051651 101 45 0,000 0,08610014 0,0971111 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,087928 0,09912695 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,087928 0,09908122 ! glycolysis GO:0006096 71 46 0,000 0,087928 0,09903554 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,087928 0,0989899 ! leukocyte migration GO:0050900 75 46 0,000 0,087928 0,09894431 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,087928 0,09889875 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,087928 0,09885324 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,087928 0,09880777 ! pigmentation GO:0043473 103 46 0,000 0,087928 0,09876234 ! cell growth GO:0016049 90 46 0,000 0,087928 0,09871695 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,087928 0,09867161 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,08975224 0,10067251 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09157289 0,10266754 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09157289 0,10262045 ! mitochondrial transport GO:0006839 94 48 0,000 0,09157289 0,10257339 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09157289 0,10252639 ! endosome transport GO:0016197 127 48 0,000 0,09157289 0,10247942 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,09157289 0,1024325 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09157289 0,10238562 ! male sex differentiation GO:0046661 93 48 0,000 0,09157289 0,10233878 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09157289 0,10229199 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09157289 0,10224523 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09157289 0,10219853 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09157289 0,10215186 ! methylation GO:0032259 97 48 0,000 0,09157289 0,10210524 ! response to calcium ion GO:0051592 94 49 0,000 0,09338995 0,10408378 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,09338995 0,10403632 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,09338995 0,1039889 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,09338995 0,10394153 ! JNK cascade GO:0007254 106 49 0,000 0,09338995 0,10389419 ! regulation of action potential GO:0001508 102 50 0,000 0,09520343 0,10586344 ! regulation of ion transport GO:0043269 86 50 0,000 0,09520343 0,10581527 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,09520343 0,10576715 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,09520343 0,10571908 ! activation of caspase activity GO:0006919 95 50 0,000 0,09520343 0,10567104 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09520343 0,10562306 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09520343 0,10557511 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09520343 0,10552721 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,09520343 0,10547935 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09520343 0,10543154 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,09701333 0,1073872 ! viral infectious cycle GO:0019058 104 51 0,000 0,09701333 0,10733857 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,09701333 0,10728997 ! peptide metabolic process GO:0006518 80 51 0,000 0,09701333 0,10724143 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09701333 0,10719292 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09701333 0,10714446 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,09701333 0,10709605 ! positive regulation of binding GO:0051099 88 52 0,000 0,09881965 0,10904084 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,09881965 0,10899161 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,09881965 0,10894243 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,09881965 0,10889329 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,09881965 0,10884419 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,09881965 0,10879514 ! excretion GO:0007588 87 52 0,000 0,09881965 0,10874613 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,09881965 0,10869717 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,09881965 0,10864825 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,09881965 0,10859938 ! amino acid activation GO:0043038 98 52 0,000 0,09881965 0,10855055 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10062242 0,11048116 ! positive regulation of growth GO:0045927 96 53 0,000 0,10062242 0,11043153 ! chromatin remodeling GO:0006338 122 53 0,000 0,10062242 0,11038194 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10062242 0,11033239 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10062242 0,1102829 ! cartilage development GO:0051216 99 53 0,000 0,10062242 0,11023344 ! synapse organization GO:0050808 102 53 0,000 0,10062242 0,11018403 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,10242163 0,11210396 ! regulation of translational initiation GO:0006446 87 54 0,000 0,10242163 0,11205376 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,10242163 0,1120036 ! neuromuscular process GO:0050905 107 54 0,000 0,10242163 0,11195349 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,10242163 0,11190342 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,10242163 0,1118534 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,10242163 0,11180342 ! regulation of cell shape GO:0008360 142 54 0,000 0,10242163 0,11175348 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,10242163 0,11170359 ! RNA catabolic process GO:0006401 103 55 0,000 0,1042173 0,11361127 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,1042173 0,11356059 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,1042173 0,11350997 ! cell recognition GO:0008037 98 55 0,000 0,1042173 0,11345938 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,1042173 0,11340884 ! cell maturation GO:0048469 107 55 0,000 0,1042173 0,11335835 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,10600942 0,11525634 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,10600942 0,11520507 ! glucose catabolic process GO:0006007 88 56 0,000 0,10600942 0,11515385 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,10600942 0,11510267 ! regulation of DNA replication GO:0006275 105 56 0,000 0,10600942 0,11505153 ! RNA elongation GO:0006354 90 56 0,000 0,10600942 0,11500045 ! chloride transport GO:0006821 102 57 0,000 0,107798 0,11688882 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,107798 0,11683696 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,107798 0,11678515 ! heart morphogenesis GO:0003007 105 57 0,000 0,107798 0,11673339 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,107798 0,11668167 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,107798 0,11662999 ! regulation of actin filament length GO:0030832 118 58 0,000 0,10958306 0,11850882 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,10958306 0,11845638 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,10958306 0,11840399 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,10958306 0,11835164 ! aging GO:0007568 112 58 0,000 0,10958306 0,11829934 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,10958306 0,11824709 ! maintenance of location GO:0051235 124 58 0,000 0,10958306 0,11819488 ! nuclear export GO:0051168 110 59 0,000 0,1113646 0,12006342 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1113646 0,12001046 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,11314262 0,12187276 ! DNA catabolic process GO:0006308 94 60 0,000 0,11314262 0,12181905 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,11314262 0,12176538 ! adult behavior GO:0030534 104 60 0,000 0,11314262 0,12171176 ! kidney development GO:0001822 133 60 0,000 0,11314262 0,12165819 ! positive regulation of secretion GO:0051047 110 61 0,000 0,11491713 0,1235119 ! regulation of cellular component size GO:0032535 125 61 0,000 0,11491713 0,12345759 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,11491713 0,12340332 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,11491713 0,1233491 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,11491713 0,12329493 ! regulation of heart contraction GO:0008016 123 61 0,000 0,11491713 0,12324081 ! camera-type eye development GO:0043010 126 61 0,000 0,11491713 0,12318673 ! proton transport GO:0015992 117 61 0,000 0,11491713 0,1231327 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,11491713 0,12307872 ! viral reproductive process GO:0022415 132 62 0,000 0,11668815 0,12492075 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,11668815 0,12486603 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,11668815 0,12481136 ! tRNA processing GO:0008033 102 62 0,000 0,11668815 0,12475674 ! regulation of mitosis GO:0007088 112 63 0,000 0,11845567 0,12659107 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,11845567 0,12653572 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,11845567 0,12648042 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,11845567 0,12642516 ! hydrogen transport GO:0006818 121 64 0,000 0,1202197 0,12825185 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,1202197 0,12819586 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,1202197 0,12813993 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,12198025 0,12995977 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,12198025 0,12990312 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,12198025 0,12984652 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,12198025 0,12978996 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,12198025 0,12973346 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,12373733 0,13154495 ! gonad development GO:0008406 115 66 0,000 0,12373733 0,13148773 ! activation of MAPK activity GO:0000187 124 67 0,000 0,12549094 0,13329321 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,12549094 0,13323528 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,12549094 0,1331774 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,12549094 0,13311957 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,12549094 0,13306179 ! secondary metabolic process GO:0019748 125 67 0,000 0,12549094 0,13300407 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,12724109 0,13480052 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,12724109 0,13474209 ! hexose catabolic process GO:0019320 113 68 0,000 0,12724109 0,13468371 ! extracellular matrix organization GO:0030198 146 68 0,000 0,12724109 0,13462538 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,12724109 0,1345671 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,12724109 0,13450887 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,12724109 0,13445069 ! viral reproduction GO:0016032 142 68 0,000 0,12724109 0,13439256 ! adaptive immune response GO:0002250 126 68 0,000 0,12724109 0,13433448 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,12724109 0,13427646 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,12898779 0,13606096 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,12898779 0,13600224 ! urogenital system development GO:0001655 149 69 0,000 0,12898779 0,13594356 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,12898779 0,13588494 ! developmental maturation GO:0021700 128 69 0,000 0,12898779 0,13582637 ! single fertilization GO:0007338 83 69 0,000 0,12898779 0,13576785 ! germ cell development GO:0007281 133 70 0,000 0,13073105 0,13754347 ! activation of immune response GO:0002253 120 70 0,000 0,13073105 0,13748426 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,13073105 0,1374251 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,13247086 0,13919411 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,13247086 0,13913427 ! appendage morphogenesis GO:0035107 150 72 0,000 0,13420724 0,14089741 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,13420724 0,14083689 ! B cell activation GO:0042113 179 72 0,000 0,13420724 0,14077642 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,13420724 0,140716 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,13420724 0,14065563 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,13420724 0,14059532 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,13420724 0,14053505 ! appendage development GO:0048736 151 73 0,000 0,13594019 0,14228872 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,13594019 0,14222779 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,13594019 0,1421669 ! regulation of immune effector process GO:0002697 156 73 0,000 0,13594019 0,14210607 ! acute inflammatory response GO:0002526 118 74 0,000 0,13766972 0,14385249 ! amino acid transport GO:0006865 148 74 0,000 0,13766972 0,14379099 ! regulation of caspase activity GO:0043281 136 74 0,000 0,13766972 0,14372954 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,13766972 0,14366815 ! organelle localization GO:0051640 155 74 0,000 0,13766972 0,1436068 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,13939584 0,1453453 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,13939584 0,14528329 ! reproductive structure development GO:0048608 131 75 0,000 0,13939584 0,14522134 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,13939584 0,14515944 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,13939584 0,14509759 ! eye development GO:0001654 155 75 0,000 0,13939584 0,14503579 ! axon guidance GO:0007411 162 75 0,000 0,13939584 0,14497405 ! rhythmic process GO:0048511 142 75 0,000 0,13939584 0,14491236 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,14111855 0,14664084 ! learning or memory GO:0007611 161 76 0,000 0,14111855 0,1465785 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,14111855 0,1465162 ! regulation of blood pressure GO:0008217 134 76 0,000 0,14111855 0,14645396 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,14111855 0,14639177 ! amine catabolic process GO:0009310 136 77 0,000 0,14283787 0,14811244 ! neurotransmitter transport GO:0006836 142 77 0,000 0,14283787 0,1480496 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,14283787 0,14798681 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,14283787 0,14792408 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,14283787 0,1478614 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,14283787 0,14779877 ! regulation of catabolic process GO:0009894 173 77 0,000 0,14283787 0,1477362 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,14455379 0,14944769 ! antigen processing and presentation GO:0019882 117 78 0,000 0,14455379 0,14938447 ! fertilization GO:0009566 99 78 0,000 0,14455379 0,14932131 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,14626632 0,15102646 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,14626632 0,15096266 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,14626632 0,15089891 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,14626632 0,15083521 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,14626632 0,15077157 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,14797547 0,15246903 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,14797547 0,15240475 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,14797547 0,15234053 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,14797547 0,15227636 ! meiosis GO:0007126 143 81 0,000 0,14968125 0,15396686 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,14968125 0,15390206 ! protein import into nucleus GO:0006606 174 82 0,000 0,15138366 0,15558699 ! meiotic cell cycle GO:0051321 144 82 0,000 0,15138366 0,15552157 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,15308271 0,15720095 ! response to drug GO:0042493 149 83 0,000 0,15308271 0,1571349 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,15308271 0,15706891 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,15308271 0,15700297 ! nuclear import GO:0051170 177 83 0,000 0,15308271 0,15693708 ! inorganic anion transport GO:0015698 156 83 0,000 0,15308271 0,15687125 ! response to metal ion GO:0010038 158 84 0,000 0,15477841 0,15854241 ! T cell activation GO:0042110 189 84 0,000 0,15477841 0,15847597 ! response to nutrient GO:0007584 135 84 0,000 0,15477841 0,15840957 ! digestion GO:0007586 130 84 0,000 0,15477841 0,15834324 ! regulation of ligase activity GO:0051340 147 84 0,000 0,15477841 0,15827696 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,15647076 0,15994061 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,15647076 0,15987372 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,15647076 0,15980688 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,15815977 0,1614644 ! regulation of lyase activity GO:0051339 169 86 0,000 0,15815977 0,16139696 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,15984544 0,16304903 ! mitochondrion organization GO:0007005 159 87 0,000 0,15984544 0,16298098 ! alcohol catabolic process GO:0046164 142 87 0,000 0,15984544 0,16291298 ! nucleosome assembly GO:0006334 126 87 0,000 0,15984544 0,16284505 ! regulation of protein transport GO:0051223 165 87 0,000 0,15984544 0,16277717 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,16152779 0,16442183 ! amine biosynthetic process GO:0009309 146 88 0,000 0,16152779 0,16435335 ! sensory perception of smell GO:0007608 117 88 0,000 0,16152779 0,16428493 ! chromatin assembly GO:0031497 128 88 0,000 0,16152779 0,16421656 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,16152779 0,16414825 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,16320682 0,16578555 ! regulation of DNA binding GO:0051101 167 89 0,000 0,16320682 0,16571665 ! cellular defense response GO:0006968 123 89 0,000 0,16320682 0,1656478 ! protein localization in nucleus GO:0034504 192 89 0,000 0,16320682 0,16557901 ! regulation of neurological system process GO:0031644 175 89 0,000 0,16320682 0,16551027 ! response to inorganic substance GO:0010035 173 90 0,000 0,16488253 0,16714025 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,16488253 0,16707093 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,16488253 0,16700166 ! response to unfolded protein GO:0006986 139 90 0,000 0,16488253 0,16693245 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,16488253 0,1668633 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,16655493 0,168486 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,16655493 0,16841626 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,16822403 0,17003364 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,16988983 0,17164634 ! amine transport GO:0015837 181 93 0,000 0,16988983 0,17157539 ! vitamin metabolic process GO:0006766 153 93 0,000 0,16988983 0,17150449 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,17155235 0,17311127 ! female pregnancy GO:0007565 166 94 0,000 0,17155235 0,1730398 ! sterol metabolic process GO:0016125 166 94 0,000 0,17155235 0,17296838 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,17155235 0,17289702 ! regulation of defense response GO:0031347 171 95 0,000 0,17321158 0,17449727 ! nucleosome organization GO:0034728 143 95 0,000 0,17321158 0,17442535 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,17321158 0,17435348 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,17321158 0,17428167 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,17321158 0,17420992 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,17321158 0,17413823 ! sex differentiation GO:0007548 171 96 0,000 0,17486754 0,17573072 ! response to protein stimulus GO:0051789 158 96 0,000 0,17486754 0,17565847 ! regulation of T cell activation GO:0050863 175 96 0,000 0,17486754 0,17558627 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,17652022 0,17717293 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,17652022 0,17710017 ! transcription initiation GO:0006352 171 97 0,000 0,17652022 0,17702746 ! regulation of protein localization GO:0032880 188 97 0,000 0,17652022 0,17695482 ! leukocyte differentiation GO:0002521 232 98 0,000 0,17816964 0,17853505 ! forebrain development GO:0030900 210 98 0,000 0,17816964 0,17846185 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,17816964 0,1783887 ! mRNA transport GO:0051028 185 100 0,000 0,18145872 0,1816074 ! positive regulation of immune response GO:0050778 175 100 0,000 0,18145872 0,18153303 ! hormone metabolic process GO:0042445 171 100 0,000 0,18145872 0,18145872