pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/614-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 2,581E-07 6,209E-04 ! positive regulation of protein polymerization GO:0032273 25 13 2,000 2,229E-06 2,681E-03 ! positive regulation of protein complex assembly GO:0031334 32 17 2,000 5,268E-06 4,225E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 5,551E-06 3,339E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 8,794E-06 4,232E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 8,835E-06 3,543E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,185E-05 4,071E-03 ! positive regulation of cytoskeleton organization GO:0051495 48 22 2,000 1,185E-05 3,562E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 1,761E-05 4,709E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,988E-05 4,784E-03 ! membrane docking GO:0022406 61 30 2,000 3,087E-05 6,752E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 4,019E-05 8,059E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 1,000 4,019E-05 7,439E-03 ! positive regulation of muscle cell differentiation GO:0051149 13 5 1,000 4,019E-05 6,908E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,019E-05 6,447E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,019E-05 6,044E-03 ! lymphocyte activation during immune response GO:0002285 9 5 1,000 4,019E-05 5,689E-03 ! negative regulation of secretion GO:0051048 63 35 2,000 4,941E-05 6,604E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 5,848E-05 7,406E-03 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 6,021E-05 7,244E-03 ! virion attachment to host cell surface receptor GO:0019062 15 6 1,000 6,021E-05 6,899E-03 ! T cell mediated immunity GO:0002456 16 6 1,000 6,021E-05 6,585E-03 ! male sex determination GO:0030238 15 6 1,000 6,021E-05 6,299E-03 ! interaction with symbiont GO:0051702 13 6 1,000 6,021E-05 6,036E-03 ! membrane to membrane docking GO:0022614 14 6 1,000 6,021E-05 5,795E-03 ! positive regulation of microtubule polymerization GO:0031116 13 6 1,000 6,021E-05 5,572E-03 ! mammary gland development GO:0030879 86 39 2,000 6,859E-05 6,112E-03 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,419E-05 7,234E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 8,419E-05 6,985E-03 ! vesicle fusion GO:0006906 17 7 1,000 8,419E-05 6,752E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 8,419E-05 6,534E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 1,000 8,419E-05 6,33E-03 ! regulation of microtubule polymerization GO:0031113 15 7 1,000 8,419E-05 6,138E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 9,209E-05 6,517E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,121E-04 7,706E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 1,121E-04 7,492E-03 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,121E-04 7,29E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 1,121E-04 7,098E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,121E-04 6,916E-03 ! leukocyte activation during immune response GO:0002366 13 8 1,000 1,121E-04 6,743E-03 GO:0002263|cell activation during immune response, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,121E-04 6,579E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 1,128E-04 6,461E-03 ! protein homooligomerization GO:0051260 76 47 2,000 1,203E-04 6,731E-03 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,439E-04 7,871E-03 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,439E-04 7,696E-03 GO:0010469|regulation of receptor activity, ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 1,439E-04 7,529E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,439E-04 7,369E-03 ! gas homeostasis GO:0033483 16 9 1,000 1,439E-04 7,215E-03 ! induction of an organ GO:0001759 14 9 1,000 1,439E-04 7,068E-03 ! regulation of protein polymerization GO:0032271 103 53 2,000 1,723E-04 8,291E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 1,797E-04 8,478E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,797E-04 8,315E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,797E-04 8,158E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,797E-04 8,007E-03 ! localization within membrane GO:0051668 20 10 1,000 1,797E-04 7,861E-03 ! positive regulation of organelle organization GO:0010638 100 56 2,000 2,03E-04 8,722E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,193E-04 9,259E-03 ! chondrocyte differentiation GO:0002062 24 11 1,000 2,193E-04 9,099E-03 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,193E-04 8,945E-03 ! embryonic gut development GO:0048566 15 11 1,000 2,193E-04 8,796E-03 ! cardiac cell differentiation GO:0035051 31 11 1,000 2,193E-04 8,652E-03 ! developmental induction GO:0031128 19 11 1,000 2,193E-04 8,512E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! lamellipodium assembly GO:0030032 20 11 1,000 2,193E-04 8,377E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 2,492E-04 9,367E-03 ! regulation of protein complex assembly GO:0043254 117 61 2,000 2,617E-04 9,686E-03 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,617E-04 9,54E-03 ! protein complex disassembly GO:0043241 27 12 1,000 2,629E-04 9,44E-03 GO:0043624|cellular protein complex disassembly, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,629E-04 9,301E-03 ! entry into host cell GO:0030260 32 12 1,000 2,629E-04 9,166E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! cranial nerve development GO:0021545 20 12 1,000 2,629E-04 9,035E-03 ! gland morphogenesis GO:0022612 29 12 1,000 2,629E-04 8,908E-03 ! lipid localization GO:0010876 28 13 1,000 3,103E-04 0,01036789 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 1,000 3,103E-04 0,01022587 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,103E-04 0,01008768 ! actin filament organization GO:0007015 148 66 2,000 3,303E-04 0,01059735 ! lung development GO:0030324 144 67 2,000 3,453E-04 0,01093238 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 3,453E-04 0,0107904 ! respiratory tube development GO:0030323 150 70 2,000 3,929E-04 0,01211945 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 4,096E-04 0,01247599 ! heterophilic cell adhesion GO:0007157 39 15 1,000 4,166E-04 0,01252836 ! regulation of vasodilation GO:0042312 26 15 1,000 4,166E-04 0,01237369 ! respiratory system development GO:0060541 153 72 2,000 4,268E-04 0,01252412 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 4,755E-04 0,01378261 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 1,000 4,755E-04 0,01361853 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,755E-04 0,01345832 ! signal complex assembly GO:0007172 41 17 1,000 5,382E-04 0,01505575 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 5,382E-04 0,01488269 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 5,382E-04 0,01471357 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 5,382E-04 0,01454825 ! regulation of protein binding GO:0043393 33 17 1,000 5,382E-04 0,01438661 ! protein oligomerization GO:0051259 139 78 2,000 5,398E-04 0,01427191 ! regulation of peptidase activity GO:0052547 134 79 2,000 5,603E-04 0,01465294 ! T cell activation GO:0042110 168 81 2,000 6,028E-04 0,01559447 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,046E-04 0,01547601 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 6,046E-04 0,01531311 ! nerve development GO:0021675 28 18 1,000 6,046E-04 0,0151536 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 6,248E-04 0,01549688 ! negative regulation of transport GO:0051051 153 84 2,000 6,703E-04 0,01645598 ! lipid phosphorylation GO:0046834 35 19 1,000 6,749E-04 0,01640175 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 6,749E-04 0,01623773 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 7,489E-04 0,01784001 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 7,489E-04 0,01766511 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 7,489E-04 0,0174936 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 7,489E-04 0,0173254 ! gland development GO:0048732 206 88 2,000 7,675E-04 0,01758706 ! regulation of cell adhesion GO:0030155 212 89 2,000 7,931E-04 0,01800298 ! ossification GO:0001503 188 90 2,000 8,193E-04 0,01842323 ! regulation of cell killing GO:0031341 42 21 1,000 8,266E-04 0,01841587 ! inactivation of MAPK activity GO:0000188 39 21 1,000 8,266E-04 0,01824692 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 8,266E-04 0,01808104 ! regulation of vasoconstriction GO:0019229 39 21 1,000 8,266E-04 0,01791814 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 8,266E-04 0,01775816 ! gut development GO:0048565 39 21 1,000 8,266E-04 0,01760101 ! bone development GO:0060348 189 91 2,000 8,46E-04 0,01785581 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 9,081E-04 0,01899961 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 9,081E-04 0,01883582 ! sex determination GO:0007530 47 23 1,000 9,933E-04 0,02042675 ! leukocyte adhesion GO:0007159 50 23 1,000 9,933E-04 0,02025364 ! vesicle docking GO:0048278 47 24 1,000 1,082E-03 0,02188068 ! membrane depolarization GO:0051899 39 24 1,000 1,082E-03 0,02169834 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,082E-03 0,02151901 ! vasculogenesis GO:0001570 46 25 1,000 1,175E-03 0,0231683 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 1,175E-03 0,02297994 ! osteoblast differentiation GO:0001649 60 25 1,000 1,175E-03 0,02279462 ! neural crest cell development GO:0014032 54 25 1,000 1,175E-03 0,02261226 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 1,175E-03 0,0224328 ! regulation of blood coagulation GO:0030193 40 25 1,000 1,175E-03 0,02225616 ! initiation of viral infection GO:0019059 57 26 1,000 1,271E-03 0,02389133 ! macromolecular complex disassembly GO:0032984 53 26 1,000 1,271E-03 0,02370613 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 1,271E-03 0,02352377 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 1,271E-03 0,0233442 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 1,271E-03 0,02316735 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 1,271E-03 0,02299316 ! male gonad development GO:0008584 44 27 1,000 1,371E-03 0,02461521 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 1,582E-03 0,02818788 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 1,582E-03 0,02798061 ! regulation of coagulation GO:0050818 46 29 1,000 1,582E-03 0,02777638 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 1,692E-03 0,0295063 ! inner ear morphogenesis GO:0042472 47 31 1,000 1,807E-03 0,03127357 ! cholesterol homeostasis GO:0042632 53 31 1,000 1,807E-03 0,03105018 GO:0055092|sterol homeostasis, ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 1,807E-03 0,03082997 ! triglyceride metabolic process GO:0006641 43 31 1,000 1,807E-03 0,03061286 ! cholesterol transport GO:0030301 56 32 1,000 1,925E-03 0,03238319 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 1,925E-03 0,0321583 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 1,925E-03 0,03193652 ! peripheral nervous system development GO:0007422 64 32 1,000 1,925E-03 0,03171778 ! cell fate specification GO:0001708 52 33 1,000 2,046E-03 0,03349078 ! sterol transport GO:0015918 57 33 1,000 2,046E-03 0,03326449 ! glial cell differentiation GO:0010001 63 34 1,000 2,171E-03 0,03506067 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 2,171E-03 0,03482693 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 2,171E-03 0,03459629 ! regulation of muscle development GO:0048634 70 35 1,000 2,3E-03 0,03640423 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 2,3E-03 0,0361663 ! neutral lipid metabolic process GO:0006638 50 35 1,000 2,3E-03 0,03593145 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 62 35 1,000 2,3E-03 0,03569963 ! regulation of microtubule-based process GO:0032886 78 35 1,000 2,3E-03 0,03547079 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 2,432E-03 0,03726957 ! embryonic organ development GO:0048568 57 36 1,000 2,432E-03 0,03703369 ! tissue remodeling GO:0048771 76 37 1,000 2,568E-03 0,0388531 ! glycerol ether metabolic process GO:0006662 53 37 1,000 2,568E-03 0,03861027 ! lipid homeostasis GO:0055088 67 38 1,000 2,707E-03 0,04044951 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 2,707E-03 0,04019982 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! ear morphogenesis GO:0042471 60 39 1,000 2,849E-03 0,0420581 ! organic ether metabolic process GO:0018904 55 39 1,000 2,849E-03 0,04180165 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 2,849E-03 0,0415483 ! mesenchymal cell development GO:0014031 87 40 1,000 2,995E-03 0,04341511 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! gliogenesis GO:0042063 88 41 1,000 3,145E-03 0,04530928 ! regulation of T cell proliferation GO:0042129 71 41 1,000 3,145E-03 0,04503958 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 3,298E-03 0,04695066 ! striated muscle cell differentiation GO:0051146 82 43 1,000 3,454E-03 0,04888771 ! male sex differentiation GO:0046661 76 44 1,000 3,614E-03 0,05085006 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 3,777E-03 0,0528371 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 3,777E-03 0,05253168 ! leukocyte migration GO:0050900 68 45 1,000 3,777E-03 0,05222978 ! cell growth GO:0016049 84 45 1,000 3,777E-03 0,05193132 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 1,000 3,944E-03 0,05391327 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 3,944E-03 0,05360868 ! positive regulation of protein transport GO:0051222 72 46 1,000 3,944E-03 0,05330751 ! positive regulation of cell cycle GO:0045787 89 48 1,000 4,287E-03 0,05762301 ! Notch signaling pathway GO:0007219 96 48 1,000 4,287E-03 0,05730288 ! cellular component disassembly GO:0022411 86 48 1,000 4,287E-03 0,05698629 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 4,287E-03 0,05667318 ! inner ear development GO:0048839 79 50 1,000 4,644E-03 0,0610516 ! viral infectious cycle GO:0019058 99 51 1,000 4,827E-03 0,06311617 ! embryonic skeletal system development GO:0048706 85 51 1,000 4,827E-03 0,062775 ! vesicle organization GO:0016050 107 51 1,000 4,827E-03 0,0624375 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 4,827E-03 0,06210361 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 1,000 5,013E-03 0,06416087 ! membrane fusion GO:0006944 110 52 1,000 5,013E-03 0,0638214 ! cartilage development GO:0051216 90 52 1,000 5,013E-03 0,06348549 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 5,203E-03 0,06554458 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 5,203E-03 0,0652032 ! response to UV GO:0009411 104 53 1,000 5,203E-03 0,06486536 ! activation of phospholipase C activity GO:0007202 103 54 1,000 5,396E-03 0,06692607 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 5,593E-03 0,06900583 ! regulation of actin filament length GO:0030832 105 56 1,000 5,792E-03 0,07110419 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 5,995E-03 0,07322071 ! lipid modification GO:0030258 97 57 1,000 5,995E-03 0,0728509 ! regulation of phospholipase activity GO:0010517 106 57 1,000 5,995E-03 0,07248482 ! regulation of intracellular transport GO:0032386 101 57 1,000 5,995E-03 0,0721224 ! positive regulation of lipase activity GO:0060193 108 58 1,000 6,201E-03 0,07423023 ! regulation of cellular component size GO:0032535 109 59 1,000 6,411E-03 0,07635536 ! ear development GO:0043583 103 62 1,000 7,057E-03 0,08364643 ! viral reproductive process GO:0022415 126 62 1,000 7,057E-03 0,0832364 ! gonad development GO:0008406 98 62 1,000 7,057E-03 0,08283037 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 7,279E-03 0,08502059 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 7,504E-03 0,08722612 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 7,733E-03 0,08944657 GO:0035113|embryonic appendage morphogenesis, ! cell projection assembly GO:0030031 120 66 1,000 7,964E-03 0,09168159 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 8,198E-03 0,09393081 ! positive regulation of T cell activation GO:0050870 109 67 1,000 8,198E-03 0,09348564 ! adaptive immune response GO:0002250 119 67 1,000 8,198E-03 0,09304467 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 131 68 1,000 8,436E-03 0,09529066 ! viral reproduction GO:0016032 134 68 1,000 8,436E-03 0,09484538 ! regulation of lipase activity GO:0060191 130 68 1,000 8,436E-03 0,09440424 ! antigen processing and presentation GO:0019882 104 69 1,000 8,677E-03 0,09664695 ! appendage morphogenesis GO:0035107 135 70 1,000 8,92E-03 0,0989029 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 1,000 9,167E-03 0,10117177 ! appendage development GO:0048736 136 71 1,000 9,167E-03 0,1007098 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 1,000 9,167E-03 0,10025203 ! regulation of caspase activity GO:0043281 122 72 1,000 9,417E-03 0,10251701 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 9,417E-03 0,10205522 ! negative regulation of transferase activity GO:0051348 140 72 1,000 9,417E-03 0,10159758 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 9,925E-03 0,10660559 ! leukocyte mediated immunity GO:0002443 128 74 1,000 9,925E-03 0,10613179 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 9,925E-03 0,10566218 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0100869 0,10691222 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0100869 0,10644331 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0100869 0,10597849 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0100869 0,10551771 ! neuron fate determination GO:0048664 7 5 0,000 0,0100869 0,10506093 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0100869 0,10460808 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0100869 0,10415912 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0100869 0,10371399 ! polyol transport GO:0015791 12 5 0,000 0,0100869 0,10327266 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0100869 0,10283506 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0100869 0,10240116 ! response to superoxide GO:0000303 10 5 0,000 0,0100869 0,1019709 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0100869 0,10154424 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0100869 0,10112114 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0100869 0,10070155 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0100869 0,10028543 ! female meiosis GO:0007143 7 5 0,000 0,0100869 0,09987273 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0100869 0,09946342 ! cobalt ion transport GO:0006824 11 5 0,000 0,0100869 0,09905745 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0100869 0,09865477 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0100869 0,09825536 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0100869 0,09785917 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0100869 0,09746616 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0100869 0,0970763 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0100869 0,09668954 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0100869 0,09630585 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0100869 0,09592519 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0100869 0,09554754 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0100869 0,09517284 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0100869 0,09480107 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0100869 0,0944322 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,0100869 0,09406618 ! negative chemotaxis GO:0050919 14 5 0,000 0,0100869 0,09370299 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0100869 0,09334259 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0100869 0,09298496 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0100869 0,09263005 ! behavioral response to pain GO:0048266 9 5 0,000 0,0100869 0,09227785 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0100869 0,09192831 ! Notch receptor processing GO:0007220 8 5 0,000 0,0100869 0,09158141 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0100869 0,09123712 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0100869 0,09089541 ! micturition GO:0060073 9 5 0,000 0,0100869 0,09055625 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0100869 0,09021961 ! copulation GO:0007620 9 5 0,000 0,0100869 0,08988546 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0100869 0,08955378 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0100869 0,08922454 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0100869 0,08889771 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0100869 0,08857326 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0100869 0,08825118 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0100869 0,08793143 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0100869 0,08761399 ! grooming behavior GO:0007625 6 5 0,000 0,0100869 0,08729883 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0100869 0,08698593 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0100869 0,08667527 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0100869 0,08636681 ! response to protozoan GO:0001562 10 5 0,000 0,0100869 0,08606055 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,0100869 0,08575645 ! lymph vessel development GO:0001945 10 5 0,000 0,0100869 0,08545449 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0100869 0,08515465 ! endochondral ossification GO:0001958 16 5 0,000 0,0100869 0,0848569 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0100869 0,08456123 ! parathyroid gland development GO:0060017 13 5 0,000 0,0100869 0,08426762 ! anagen GO:0042640 6 5 0,000 0,0100869 0,08397604 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0100869 0,08368646 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0100869 0,08339888 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0100869 0,08311327 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0100869 0,0828296 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0100869 0,08254787 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0100869 0,08226805 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0100869 0,08199012 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0100869 0,08171405 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0100869 0,08143985 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0100869 0,08116747 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0100869 0,08089691 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0100869 0,08062815 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0100869 0,08036117 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0100869 0,08009595 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0100869 0,07983248 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0100869 0,07957074 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0100869 0,0793107 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0100869 0,07905236 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0100869 0,0787957 ! histidine catabolic process GO:0006548 6 5 0,000 0,0100869 0,07854069 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0100869 0,07828734 ! microvillus organization GO:0032528 7 5 0,000 0,0100869 0,07803561 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,0100869 0,07778549 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0100869 0,07753698 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0100869 0,07729005 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0100869 0,07704468 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0100869 0,07680087 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0100869 0,07655859 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0100869 0,07631784 ! polyol catabolic process GO:0046174 7 5 0,000 0,0100869 0,0760786 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0100869 0,07584086 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0100869 0,07560459 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0100869 0,0753698 ! muscle cell migration GO:0014812 8 5 0,000 0,0100869 0,07513645 ! mitochondrial fission GO:0000266 8 5 0,000 0,0100869 0,07490455 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0100869 0,07467407 ! mRNA transcription GO:0009299 9 5 0,000 0,0100869 0,07444501 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0100869 0,07421735 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0100869 0,07399108 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0100869 0,07376618 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0100869 0,07354265 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0100869 0,07332047 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0100869 0,07309962 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0100869 0,0728801 ! response to food GO:0032094 6 5 0,000 0,0100869 0,0726619 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0100869 0,072445 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0100869 0,07222939 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0100869 0,07201506 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0100869 0,07180199 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0100869 0,07159019 ! forebrain neuron development GO:0021884 13 5 0,000 0,0100869 0,07137963 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0100869 0,07117031 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0100869 0,07096221 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0100869 0,07075532 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0100869 0,07054963 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0100869 0,07034514 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0100869 0,07014183 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0100869 0,0699397 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0100869 0,06973872 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0100869 0,06953889 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0100869 0,06934021 ! basic amino acid transport GO:0015802 11 5 0,000 0,0100869 0,06914266 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0100869 0,06894623 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0100869 0,06875092 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0100869 0,06855671 ! depyrimidination GO:0045008 10 5 0,000 0,0100869 0,06836359 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0100869 0,06817156 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0100869 0,0679806 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0100869 0,06779071 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0100869 0,06760188 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0100869 0,0674141 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0100869 0,06722735 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0100869 0,06704164 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0100869 0,06685695 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0100869 0,06667328 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0100869 0,06649061 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0100869 0,06630895 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0100869 0,06612827 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0100869 0,06594857 ! response to arsenic GO:0046685 10 5 0,000 0,0100869 0,06576985 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0100869 0,06559209 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0100869 0,06541529 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0100869 0,06523945 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0100869 0,06506454 ! response to cadmium ion GO:0046686 7 5 0,000 0,0100869 0,06489057 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0100869 0,06471753 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0100869 0,06454541 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0100869 0,0643742 ! decidualization GO:0046697 11 5 0,000 0,0100869 0,0642039 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0100869 0,0640345 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0100869 0,06386598 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0100869 0,06369836 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0100869 0,06353161 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0100869 0,06336573 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0100869 0,06320071 ! neural tube patterning GO:0021532 7 5 0,000 0,0100869 0,06303656 ! embryonic cleavage GO:0040016 6 5 0,000 0,0100869 0,06287325 ! peroxisome fission GO:0016559 5 5 0,000 0,0100869 0,06271079 ! histone demethylation GO:0016577 10 5 0,000 0,0100869 0,06254916 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0100869 0,06238837 ! mitotic recombination GO:0006312 9 5 0,000 0,0100869 0,0622284 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0100869 0,06206924 ! metaphase plate congression GO:0051310 7 5 0,000 0,0100869 0,0619109 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0100869 0,06175337 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0100869 0,06159664 ! enteric nervous system development GO:0048484 8 5 0,000 0,0100869 0,06144069 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0100869 0,06128554 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0100869 0,06113117 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0100869 0,06097757 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0100869 0,06082475 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0100869 0,06067269 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0100869 0,06052138 ! plasminogen activation GO:0031639 5 5 0,000 0,0100869 0,06037083 ! B cell homeostasis GO:0001782 13 5 0,000 0,0100869 0,06022103 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0100869 0,06007197 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0100869 0,05992364 ! metaphase GO:0051323 8 5 0,000 0,0100869 0,05977604 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0100869 0,05962918 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0100869 0,05948303 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0100869 0,05933759 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0100869 0,05919286 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0100869 0,05904884 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0100869 0,05890552 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0100869 0,05876289 ! response to redox state GO:0051775 5 5 0,000 0,0100869 0,05862095 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0100869 0,0584797 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0100869 0,05833912 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0100869 0,05819922 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0100869 0,05805999 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0100869 0,05792142 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0100869 0,05778351 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0100869 0,05764626 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0100869 0,05750965 ! striatum development GO:0021756 9 5 0,000 0,0100869 0,0573737 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0100869 0,05723838 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0100869 0,0571037 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0100869 0,05696966 ! glial cell migration GO:0008347 11 5 0,000 0,0100869 0,05683624 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0100869 0,05670344 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0100869 0,05657127 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0100869 0,05643971 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0100869 0,05630876 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0100869 0,05617841 ! neuroprotection GO:0043526 6 5 0,000 0,0100869 0,05604867 ! neural plate development GO:0001840 8 5 0,000 0,0100869 0,05591953 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0100869 0,05579098 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0100869 0,05566301 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0100869 0,05553564 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0100869 0,05540885 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0100869 0,05528263 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0100869 0,05515699 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0100869 0,05503191 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0100869 0,05490741 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0100869 0,05478346 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0100869 0,05466008 ! spindle assembly GO:0051225 6 5 0,000 0,0100869 0,05453725 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0100869 0,05441496 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0100869 0,05429323 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0100869 0,05417204 ! drug metabolic process GO:0017144 6 5 0,000 0,0100869 0,05405139 ! stem cell division GO:0017145 11 5 0,000 0,0100869 0,05393128 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0100869 0,05381169 ! organ regeneration GO:0031100 7 5 0,000 0,0100869 0,05369264 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0100869 0,05357412 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0100869 0,05345611 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0100869 0,05333862 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,0104455 0,05511373 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,01071018 0,05638664 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01071018 0,05626353 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01124841 0,05896224 ! muscle cell differentiation GO:0042692 159 80 1,000 0,01152192 0,06026467 ! protein import into nucleus GO:0006606 158 80 1,000 0,01152192 0,06013395 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01179836 0,0614434 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01179836 0,06131069 ! nuclear import GO:0051170 161 81 1,000 0,01179836 0,06117855 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01209223 0,06256756 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01209223 0,06243329 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01209223 0,0622996 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01209223 0,06216648 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01209223 0,06203393 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01209223 0,06190195 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01209223 0,06177052 ! sleep GO:0030431 13 6 0,000 0,01209223 0,06163965 ! response to oxygen radical GO:0000305 11 6 0,000 0,01209223 0,06150933 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01209223 0,06137957 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01209223 0,06125035 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01209223 0,06112167 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01209223 0,06099353 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01209223 0,06086593 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01209223 0,06073886 ! forebrain regionalization GO:0021871 8 6 0,000 0,01209223 0,06061232 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01209223 0,06048631 ! male meiosis GO:0007140 7 6 0,000 0,01209223 0,06036082 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01209223 0,06023585 ! response to zinc ion GO:0010043 9 6 0,000 0,01209223 0,06011139 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01209223 0,05998745 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01209223 0,05986402 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01209223 0,0597411 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01209223 0,05961868 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01209223 0,05949676 ! malate metabolic process GO:0006108 11 6 0,000 0,01209223 0,05937534 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01209223 0,05925441 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01209223 0,05913397 ! protein refolding GO:0042026 15 6 0,000 0,01209223 0,05901403 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01209223 0,05889456 ! opsonization GO:0008228 8 6 0,000 0,01209223 0,05877558 ! mating behavior GO:0007617 7 6 0,000 0,01209223 0,05865709 ! neuron remodeling GO:0016322 15 6 0,000 0,01209223 0,05853906 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01209223 0,05842151 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01209223 0,05830444 ! equilibrioception GO:0050957 14 6 0,000 0,01209223 0,05818783 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01209223 0,05807169 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01209223 0,057956 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01209223 0,05784078 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01209223 0,05772602 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01209223 0,05761171 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01209223 0,05749785 ! toxin metabolic process GO:0009404 11 6 0,000 0,01209223 0,05738445 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01209223 0,05727149 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01209223 0,05715897 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01209223 0,05704689 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01209223 0,05693525 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01209223 0,05682405 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01209223 0,05671328 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01209223 0,05660295 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01209223 0,05649304 ! thymic T cell selection GO:0045061 12 6 0,000 0,01209223 0,05638356 ! protein lipoylation GO:0009249 10 6 0,000 0,01209223 0,0562745 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01209223 0,05616586 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01209223 0,05605764 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01209223 0,05594984 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01209223 0,05584245 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01209223 0,05573547 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01209223 0,0556289 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01209223 0,05552274 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01209223 0,05541698 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01209223 0,05531162 ! hyperosmotic response GO:0006972 9 6 0,000 0,01209223 0,05520667 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01209223 0,05510211 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01209223 0,05499795 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01209223 0,05489418 ! urea metabolic process GO:0019627 7 6 0,000 0,01209223 0,0547908 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01209223 0,05468781 ! neutrophil activation GO:0042119 8 6 0,000 0,01209223 0,05458521 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01209223 0,05448299 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01209223 0,05438115 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01209223 0,05427969 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01209223 0,05417861 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01209223 0,05407791 ! neuron apoptosis GO:0051402 9 6 0,000 0,01209223 0,05397758 ! nucleoside salvage GO:0043174 9 6 0,000 0,01209223 0,05387762 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01209223 0,05377803 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01209223 0,05367881 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01209223 0,05357995 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01209223 0,05348146 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01209223 0,05338333 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01209223 0,05328556 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01209223 0,05318814 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01209223 0,05309108 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01209223 0,05299438 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01209223 0,05289803 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01209223 0,05280202 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01209223 0,05270637 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01209223 0,05261106 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01209223 0,05251609 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01209223 0,05242147 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01209223 0,05232718 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01209223 0,05223324 ! neural nucleus development GO:0048857 14 6 0,000 0,01209223 0,05213963 ! response to UV-C GO:0010225 11 6 0,000 0,01209223 0,05204636 ! astrocyte development GO:0014002 15 6 0,000 0,01209223 0,05195342 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01209223 0,05186081 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01209223 0,05176853 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01209223 0,05167658 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01209223 0,05158495 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01209223 0,05149365 ! response to copper ion GO:0046688 10 6 0,000 0,01209223 0,05140268 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01209223 0,05131202 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01209223 0,05122168 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01209223 0,05113166 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01209223 0,05104196 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01209223 0,05095256 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01209223 0,05086349 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01209223 0,05077472 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01209223 0,05068626 ! hair follicle maturation GO:0048820 7 6 0,000 0,01209223 0,05059811 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01209223 0,05051027 ! Schwann cell development GO:0014044 15 6 0,000 0,01209223 0,05042273 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01209223 0,05033549 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01209223 0,05024856 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01209223 0,05016192 ! subpallium development GO:0021544 10 6 0,000 0,01209223 0,05007558 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01209223 0,04998954 ! histone ubiquitination GO:0016574 8 6 0,000 0,01209223 0,0499038 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01209223 0,04981835 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01209223 0,04973319 ! G2 phase GO:0051319 16 6 0,000 0,01209223 0,04964832 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01209223 0,04956374 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01209223 0,04947945 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01209223 0,04939544 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01209223 0,04931172 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01209223 0,04922828 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01209223 0,04914513 ! receptor internalization GO:0031623 10 6 0,000 0,01209223 0,04906225 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01209223 0,04897965 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01209223 0,04889734 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01209223 0,04881529 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01209223 0,04873352 ! protein deubiquitination GO:0016579 14 6 0,000 0,01209223 0,04865203 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01209223 0,04857081 ! protein destabilization GO:0031648 9 6 0,000 0,01209223 0,04848986 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01209223 0,04840918 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01209223 0,04832876 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01209223 0,04824861 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01209223 0,04816873 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01209223 0,04808911 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01209223 0,04800976 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01209223 0,04793067 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01209223 0,04785183 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01209223 0,04777326 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01209223 0,04769494 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01209223 0,04761688 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01209223 0,04753908 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01209223 0,04746152 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01209223 0,04738423 ! catecholamine transport GO:0051937 9 6 0,000 0,01209223 0,04730718 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01209223 0,04723038 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01209223 0,04715383 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01209223 0,04707753 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01209223 0,04700148 ! maternal placenta development GO:0001893 12 6 0,000 0,01209223 0,04692567 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01209223 0,0468501 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01209223 0,04677478 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01209223 0,0466997 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01209223 0,04662486 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01209223 0,04655026 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01209223 0,0464759 ! response to oxygen levels GO:0070482 176 83 1,000 0,01235993 0,04742902 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01293303 0,04954914 GO:0002696|positive regulation of leukocyte activation, ! protein localization in nucleus GO:0034504 176 87 1,000 0,01351754 0,05170622 ! regulation of protein transport GO:0051223 154 87 1,000 0,01351754 0,05162415 GO:0070201|regulation of establishment of protein localization, ! tRNA transcription GO:0009304 14 7 0,000 0,01409357 0,05373873 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01409357 0,0536537 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01409357 0,05356894 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01409357 0,05348445 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01409357 0,05340022 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01409357 0,05331626 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01409357 0,05323256 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01409357 0,05314912 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01409357 0,05306595 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01409357 0,05298303 ! prostate gland development GO:0030850 13 7 0,000 0,01409357 0,05290038 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01409357 0,05281798 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01409357 0,05273583 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01409357 0,05265394 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01409357 0,05257231 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01409357 0,05249093 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01409357 0,0524098 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01409357 0,05232892 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01409357 0,05224829 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01409357 0,05216791 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01409357 0,05208777 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01409357 0,05200788 ! glycolipid transport GO:0046836 10 7 0,000 0,01409357 0,05192824 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01409357 0,05184884 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01409357 0,05176968 ! neuron adhesion GO:0007158 12 7 0,000 0,01409357 0,05169076 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01409357 0,05161209 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01409357 0,05153365 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01409357 0,05145545 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01409357 0,05137749 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01409357 0,05129976 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01409357 0,05122227 ! mRNA stabilization GO:0048255 18 7 0,000 0,01409357 0,05114501 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01409357 0,05106798 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01409357 0,05099119 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01409357 0,05091463 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01409357 0,05083829 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01409357 0,05076219 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01409357 0,05068631 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01409357 0,05061066 ! lipoprotein transport GO:0042953 14 7 0,000 0,01409357 0,05053523 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01409357 0,05046003 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01409357 0,05038505 ! rhythmic behavior GO:0007622 15 7 0,000 0,01409357 0,0503103 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01409357 0,05023576 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01409357 0,05016145 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01409357 0,05008736 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01409357 0,05001348 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01409357 0,04993982 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01409357 0,04986638 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01409357 0,04979316 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01409357 0,04972015 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01409357 0,04964735 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01409357 0,04957477 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01409357 0,04950239 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01409357 0,04943023 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01409357 0,04935828 ! spinal cord patterning GO:0021511 13 7 0,000 0,01409357 0,04928654 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01409357 0,04921501 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01409357 0,04914368 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01409357 0,04907256 ! adrenal gland development GO:0030325 17 7 0,000 0,01409357 0,04900165 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01409357 0,04893094 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01409357 0,04886043 ! ovulation GO:0030728 9 7 0,000 0,01409357 0,04879013 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01409357 0,04872003 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01409357 0,04865013 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,01409357 0,04858043 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01409357 0,04851093 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01409357 0,04844163 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01409357 0,04837253 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01409357 0,04830362 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01409357 0,04823491 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01409357 0,04816639 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01409357 0,04809807 ! galactose metabolic process GO:0006012 13 7 0,000 0,01409357 0,04802994 ! response to dietary excess GO:0002021 8 7 0,000 0,01409357 0,04796201 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01409357 0,04789427 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01409357 0,04782671 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01409357 0,04775935 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01409357 0,04769218 ! organ growth GO:0035265 15 7 0,000 0,01409357 0,0476252 ! purine salvage GO:0043101 10 7 0,000 0,01409357 0,0475584 ! nucleoside transport GO:0015858 8 7 0,000 0,01409357 0,04749179 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01409357 0,04742537 ! parturition GO:0007567 14 7 0,000 0,01409357 0,04735913 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01409357 0,04729308 ! rRNA modification GO:0000154 14 7 0,000 0,01409357 0,04722722 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01409357 0,04716153 ! spindle checkpoint GO:0031577 15 7 0,000 0,01409357 0,04709603 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01409357 0,04703071 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01409357 0,04696557 ! macrophage differentiation GO:0030225 11 7 0,000 0,01409357 0,04690061 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01409357 0,04683583 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01409357 0,04677123 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01409357 0,04670681 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01409357 0,04664256 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01409357 0,04657849 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01409357 0,0465146 ! fibrinolysis GO:0042730 10 7 0,000 0,01409357 0,04645088 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01409357 0,04638733 ! eating behavior GO:0042755 7 7 0,000 0,01409357 0,04632396 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01409357 0,04626076 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01409357 0,04619774 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01409357 0,04613488 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01409357 0,0460722 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01409357 0,04600969 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01409357 0,04594734 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01409357 0,04588517 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01409357 0,04582316 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01409357 0,04576132 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01409357 0,04569965 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01409357 0,04563814 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01409357 0,0455768 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01409357 0,04551562 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01409357 0,04545461 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01409357 0,04539376 ! regulation of meiosis GO:0040020 12 7 0,000 0,01409357 0,04533308 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01409357 0,04527255 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01409357 0,04521219 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01409357 0,04515198 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01409357 0,04509194 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01409357 0,04503206 ! transcription termination GO:0006353 13 7 0,000 0,01409357 0,04497233 ! response to tumor cell GO:0002347 13 7 0,000 0,01409357 0,04491277 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,01409357 0,04485336 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01409357 0,04479411 ! anaphase GO:0051322 17 7 0,000 0,01409357 0,04473501 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01409357 0,04467607 ! axonal fasciculation GO:0007413 18 7 0,000 0,01409357 0,04461729 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01409357 0,04455866 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01409357 0,04450018 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01409357 0,04444186 ! diuresis GO:0030146 12 7 0,000 0,01409357 0,04438369 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01409357 0,04432567 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01409357 0,04426781 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01409357 0,04421009 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01409357 0,04415253 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01409357 0,04409511 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01409357 0,04403784 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01409357 0,04398073 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01409357 0,04392376 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01409357 0,04386693 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01409357 0,04381026 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01409357 0,04375373 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01409357 0,04369735 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,01409357 0,04364111 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01409357 0,04358501 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01409357 0,04352906 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01409357 0,04347326 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01409357 0,04341759 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01409357 0,04336207 ! adult feeding behavior GO:0008343 9 7 0,000 0,01409357 0,04330669 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01409357 0,04325145 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01409357 0,04319636 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01409357 0,0431414 ! muscle adaptation GO:0043500 14 7 0,000 0,01409357 0,04308658 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01409357 0,0430319 ! retina homeostasis GO:0001895 12 7 0,000 0,01409357 0,04297736 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01409357 0,04292296 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01409357 0,0428687 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01409357 0,04281457 ! protein prenylation GO:0018342 18 7 0,000 0,01409357 0,04276058 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01409357 0,04270673 ! sex differentiation GO:0007548 145 90 1,000 0,01441553 0,04362737 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,01533866 0,04636283 ! regulation of membrane potential GO:0042391 164 93 1,000 0,01533866 0,04630466 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,01533866 0,04624663 ! regulation of T cell activation GO:0050863 158 94 1,000 0,0156519 0,04713201 ! interphase of mitotic cell cycle GO:0051329 209 95 1,000 0,01596789 0,04802343 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,01609093 0,04833305 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,01609093 0,04827278 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,01609093 0,04821267 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,01609093 0,0481527 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,01609093 0,04809288 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01609093 0,04803321 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01609093 0,04797369 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,01609093 0,04791432 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,01609093 0,04785509 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,01609093 0,04779601 ! meiotic prophase I GO:0007128 13 8 0,000 0,01609093 0,04773708 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01609093 0,04767829 ! oligopeptide transport GO:0006857 15 8 0,000 0,01609093 0,04761964 ! UTP metabolic process GO:0046051 8 8 0,000 0,01609093 0,04756114 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,01609093 0,04750279 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,01609093 0,04744457 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,01609093 0,0473865 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01609093 0,04732857 ! succinate metabolic process GO:0006105 14 8 0,000 0,01609093 0,04727078 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01609093 0,04721314 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01609093 0,04715563 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,01609093 0,04709826 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01609093 0,04704103 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,01609093 0,04698395 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01609093 0,046927 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01609093 0,04687018 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,01609093 0,04681351 ! reflex GO:0060004 16 8 0,000 0,01609093 0,04675697 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,01609093 0,04670057 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,01609093 0,0466443 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01609093 0,04658817 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,01609093 0,04653218 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,01609093 0,04647632 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,01609093 0,04642059 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01609093 0,046365 ! pigment granule organization GO:0048753 16 8 0,000 0,01609093 0,04630953 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01609093 0,04625421 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,01609093 0,04619901 ! astrocyte differentiation GO:0048708 18 8 0,000 0,01609093 0,04614395 ! histidine metabolic process GO:0006547 16 8 0,000 0,01609093 0,04608901 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01609093 0,04603421 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,01609093 0,04597954 ! glycine catabolic process GO:0006546 13 8 0,000 0,01609093 0,045925 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,01609093 0,04587058 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,01609093 0,0458163 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,01609093 0,04576214 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,01609093 0,04570811 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,01609093 0,04565421 ! melanin metabolic process GO:0006582 15 8 0,000 0,01609093 0,04560044 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,01609093 0,04554679 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01609093 0,04549327 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01609093 0,04543987 ! macrophage activation GO:0042116 12 8 0,000 0,01609093 0,0453866 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01609093 0,04533346 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01609093 0,04528043 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,01609093 0,04522754 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01609093 0,04517476 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,01609093 0,04512211 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01609093 0,04506958 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,01609093 0,04501718 ! osteoblast development GO:0002076 16 8 0,000 0,01609093 0,04496489 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,01609093 0,04491273 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,01609093 0,04486069 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,01609093 0,04480876 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,01609093 0,04475696 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01609093 0,04470528 ! response to UV-B GO:0010224 16 8 0,000 0,01609093 0,04465372 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,01609093 0,04460227 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01609093 0,04455094 ! intermediate filament organization GO:0045109 12 8 0,000 0,01609093 0,04449974 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,01609093 0,04444865 ! cellular extravasation GO:0045123 12 8 0,000 0,01609093 0,04439767 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,01609093 0,04434682 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,01609093 0,04429608 ! response to antibiotic GO:0046677 11 8 0,000 0,01609093 0,04424545 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,01609093 0,04419494 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,01609093 0,04414455 ! DNA topological change GO:0006265 12 8 0,000 0,01609093 0,04409427 ! response to tropane GO:0014073 15 8 0,000 0,01609093 0,04404411 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,01609093 0,04399406 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,01609093 0,04394412 ! melanosome transport GO:0032402 13 8 0,000 0,01609093 0,0438943 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,01609093 0,04384459 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01609093 0,04379499 ! mast cell activation GO:0045576 14 8 0,000 0,01609093 0,0437455 ! multicellular organismal aging GO:0010259 18 8 0,000 0,01609093 0,04369613 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,01609093 0,04364687 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,01609093 0,04359772 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,01609093 0,04354867 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01609093 0,04349974 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01609093 0,04345092 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,01609093 0,04340221 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01609093 0,04335361 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,01609093 0,04330511 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,01609093 0,04325673 ! intracellular lipid transport GO:0032365 13 8 0,000 0,01609093 0,04320845 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01609093 0,04316028 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01609093 0,04311222 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,01609093 0,04306426 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,01609093 0,04301641 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01609093 0,04296867 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,01609093 0,04292103 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,01609093 0,0428735 ! hormone catabolic process GO:0042447 17 8 0,000 0,01609093 0,04282607 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01609093 0,04277875 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,01609093 0,04273154 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,01609093 0,04268442 ! ATP catabolic process GO:0006200 11 8 0,000 0,01609093 0,04263741 ! blastocyst growth GO:0001832 19 8 0,000 0,01609093 0,04259051 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01609093 0,0425437 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01609093 0,042497 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,01609093 0,04245041 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01609093 0,04240391 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01609093 0,04235752 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,01609093 0,04231123 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,01609093 0,04226503 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,01609093 0,04221894 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,01609093 0,04217295 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,01609093 0,04212706 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,01609093 0,04208127 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01609093 0,04203558 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,01609093 0,04198999 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01609093 0,0419445 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01609093 0,0418991 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,01609093 0,04185381 ! regulation of protein localization GO:0032880 176 97 1,000 0,01660806 0,04315225 ! interphase GO:0051325 213 98 1,000 0,01693221 0,04394704 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,01725907 0,0447471 GO:0060538|skeletal muscle organ development, ! regulation of developmental growth GO:0048638 15 9 0,000 0,0180843 0,0468362 ! axon extension GO:0048675 15 9 0,000 0,0180843 0,04678583 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0180843 0,04673558 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,0180843 0,04668544 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0180843 0,0466354 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0180843 0,04658547 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0180843 0,04653564 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0180843 0,04648592 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0180843 0,04643631 ! phosphate transport GO:0006817 19 9 0,000 0,0180843 0,04638681 ! reproductive behavior GO:0019098 19 9 0,000 0,0180843 0,04633741 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0180843 0,04628811 ! CTP metabolic process GO:0046036 9 9 0,000 0,0180843 0,04623892 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0180843 0,04618984 ! GTP metabolic process GO:0046039 9 9 0,000 0,0180843 0,04614085 ! RNA methylation GO:0001510 15 9 0,000 0,0180843 0,04609198 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0180843 0,0460432 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0180843 0,04599453 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0180843 0,04594596 ! artery development GO:0060840 24 9 0,000 0,0180843 0,0458975 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0180843 0,04584913 ! regulation of glycolysis GO:0006110 21 9 0,000 0,0180843 0,04580087 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0180843 0,04575271 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0180843 0,04570465 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0180843 0,04565669 ! chemosensory behavior GO:0007635 20 9 0,000 0,0180843 0,04560883 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0180843 0,04556107 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0180843 0,04551342 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0180843 0,04546586 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0180843 0,0454184 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0180843 0,04537104 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0180843 0,04532378 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0180843 0,04527661 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0180843 0,04522955 ! protein targeting to ER GO:0045047 22 9 0,000 0,0180843 0,04518258 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0180843 0,04513571 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0180843 0,04508894 ! T cell selection GO:0045058 23 9 0,000 0,0180843 0,04504226 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0180843 0,04499568 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0180843 0,0449492 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0180843 0,04490281 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0180843 0,04485652 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0180843 0,04481032 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0180843 0,04476422 ! mannose metabolic process GO:0006013 13 9 0,000 0,0180843 0,04471822 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0180843 0,04467231 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0180843 0,04462649 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0180843 0,04458076 ! receptor clustering GO:0043113 18 9 0,000 0,0180843 0,04453513 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0180843 0,0444896 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0180843 0,04444415 ! ruffle organization GO:0031529 15 9 0,000 0,0180843 0,0443988 ! retinol metabolic process GO:0042572 18 9 0,000 0,0180843 0,04435354 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0180843 0,04430838 ! behavioral fear response GO:0001662 22 9 0,000 0,0180843 0,0442633 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0180843 0,04421832 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0180843 0,04417343 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0180843 0,04412863 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,0180843 0,04408392 ! protein heterooligomerization GO:0051291 16 9 0,000 0,0180843 0,0440393 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0180843 0,04399477 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0180843 0,04395033 ! segment specification GO:0007379 13 9 0,000 0,0180843 0,04390598 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0180843 0,04386172 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0180843 0,04381755 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0180843 0,04377347 ! response to amine stimulus GO:0014075 13 9 0,000 0,0180843 0,04372947 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0180843 0,04368557 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0180843 0,04364175 ! erythrocyte development GO:0048821 15 9 0,000 0,0180843 0,04359802 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0180843 0,04355438 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0180843 0,04351083 ! renal water homeostasis GO:0003091 14 9 0,000 0,0180843 0,04346736 ! postreplication repair GO:0006301 22 9 0,000 0,0180843 0,04342398 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0180843 0,04338068 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0180843 0,04333748 ! icosanoid secretion GO:0032309 15 9 0,000 0,0180843 0,04329435 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0180843 0,04325132 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0180843 0,04320837 ! regulation of cell division GO:0051302 15 9 0,000 0,0180843 0,0431655 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0180843 0,04312272 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0180843 0,04308003 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0180843 0,04303741 ! sterol catabolic process GO:0016127 11 9 0,000 0,0180843 0,04299489 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0180843 0,04295244 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0180843 0,04291008 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0180843 0,04286781 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0180843 0,04282562 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0180843 0,04278351 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0180843 0,04274148 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0180843 0,04269953 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0180843 0,04265767 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0180843 0,04261589 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0180843 0,04257419 ! purine base metabolic process GO:0006144 21 9 0,000 0,0180843 0,04253258 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0180843 0,04249104 ! pigment granule transport GO:0051904 17 9 0,000 0,0180843 0,04244959 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0180843 0,04240821 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0180843 0,04236692 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0180843 0,04232571 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0180843 0,04228457 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0180843 0,04224352 ! mitochondrion localization GO:0051646 15 9 0,000 0,0180843 0,04220255 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0200737 0,04679973 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,0200737 0,04675443 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0200737 0,04670921 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0200737 0,04666408 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,0200737 0,04661904 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0200737 0,04657408 ! synapsis GO:0007129 13 10 0,000 0,0200737 0,04652921 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0200737 0,04648443 ! N-glycan processing GO:0006491 20 10 0,000 0,0200737 0,04643973 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0200737 0,04639512 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0200737 0,0463506 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0200737 0,04630616 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0200737 0,0462618 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0200737 0,04621753 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,0200737 0,04617335 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0200737 0,04612925 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0200737 0,04608523 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0200737 0,0460413 ! androgen metabolic process GO:0008209 17 10 0,000 0,0200737 0,04599745 ! phospholipid efflux GO:0033700 16 10 0,000 0,0200737 0,04595368 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0200737 0,04591 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0200737 0,0458664 ! lung alveolus development GO:0048286 26 10 0,000 0,0200737 0,04582289 ! pathogenesis GO:0009405 13 10 0,000 0,0200737 0,04577945 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0200737 0,0457361 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0200737 0,04569283 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0200737 0,04564964 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0200737 0,04560654 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0200737 0,04556351 ! endoderm development GO:0007492 16 10 0,000 0,0200737 0,04552057 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0200737 0,0454777 ! arginine catabolic process GO:0006527 13 10 0,000 0,0200737 0,04543492 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0200737 0,04539222 ! proline metabolic process GO:0006560 13 10 0,000 0,0200737 0,0453496 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0200737 0,04530706 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0200737 0,04526459 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0200737 0,04522221 ! V(D)J recombination GO:0033151 28 10 0,000 0,0200737 0,04517991 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0200737 0,04513768 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0200737 0,04509554 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0200737 0,04505347 ! B cell proliferation GO:0042100 18 10 0,000 0,0200737 0,04501148 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0200737 0,04496957 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0200737 0,04492774 ! multicellular organism growth GO:0035264 18 10 0,000 0,0200737 0,04488599 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0200737 0,04484431 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0200737 0,04480271 ! epithelial cell development GO:0002064 20 10 0,000 0,0200737 0,04476119 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0200737 0,04471974 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0200737 0,04467837 ! macroautophagy GO:0016236 17 10 0,000 0,0200737 0,04463708 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0200737 0,04459587 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0200737 0,04455473 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0200737 0,04451366 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,0200737 0,04447267 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0200737 0,04443176 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0200737 0,04439092 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0200737 0,04435016 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0200737 0,04430947 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0200737 0,04426886 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0200737 0,04422832 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0200737 0,04418785 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,0200737 0,04414746 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0200737 0,04410714 ! response to dsRNA GO:0043331 20 10 0,000 0,0200737 0,0440669 ! DNA ligation GO:0006266 19 10 0,000 0,0200737 0,04402673 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0200737 0,04398663 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0200737 0,04394661 ! melanosome localization GO:0032400 16 10 0,000 0,0200737 0,04390666 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0200737 0,04386678 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0200737 0,04382697 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0200737 0,04378724 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0200737 0,04374757 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0200737 0,04370798 ! mRNA cleavage GO:0006379 17 10 0,000 0,0200737 0,04366846 ! protein sumoylation GO:0016925 15 10 0,000 0,0200737 0,04362902 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0200737 0,04358964 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0200737 0,04355034 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0200737 0,0435111 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0200737 0,04347194 ! salivary gland development GO:0007431 27 10 0,000 0,0200737 0,04343284 ! prophase GO:0051324 15 10 0,000 0,0200737 0,04339382 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0200737 0,04335487 ! apical protein localization GO:0045176 15 10 0,000 0,0200737 0,04331598 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0200737 0,04327717 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0200737 0,04323843 ! midbrain development GO:0030901 13 10 0,000 0,0200737 0,04319975 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0200737 0,04316115 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0200737 0,04312261 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0200737 0,04308414 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0200737 0,04304574 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0200737 0,04300741 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0200737 0,04296915 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0200737 0,04293095 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,0200737 0,04289283 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,0200737 0,04285477 ! oocyte development GO:0048599 17 10 0,000 0,0200737 0,04281677 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0200737 0,04277885 ! blastocyst formation GO:0001825 17 10 0,000 0,0200737 0,04274099 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0200737 0,0427032 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0200737 0,04266548 ! activation of innate immune response GO:0002218 12 10 0,000 0,0200737 0,04262782 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0200737 0,04259023 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0200737 0,04255271 ! response to nicotine GO:0035094 20 10 0,000 0,0200737 0,04251525 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0200737 0,04247786 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,0200737 0,04244053 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02205914 0,04659726 ! respiratory burst GO:0045730 17 11 0,000 0,02205914 0,04655639 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02205914 0,04651558 ! neuron fate specification GO:0048665 17 11 0,000 0,02205914 0,04647485 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02205914 0,04643419 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02205914 0,0463936 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02205914 0,04635308 ! thyroid gland development GO:0030878 26 11 0,000 0,02205914 0,04631264 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02205914 0,04627226 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02205914 0,04623195 ! response to pain GO:0048265 24 11 0,000 0,02205914 0,04619171 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02205914 0,04615155 ! T cell proliferation GO:0042098 26 11 0,000 0,02205914 0,04611145 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02205914 0,04607142 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02205914 0,04603147 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02205914 0,04599158 ! bone resorption GO:0045453 16 11 0,000 0,02205914 0,04595176 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,02205914 0,04591201 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02205914 0,04587232 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02205914 0,04583271 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02205914 0,04579317 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02205914 0,04575369 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02205914 0,04571428 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02205914 0,04567494 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02205914 0,04563567 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02205914 0,04559646 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02205914 0,04555732 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02205914 0,04551825 ! lipid digestion GO:0044241 18 11 0,000 0,02205914 0,04547925 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02205914 0,04544031 ! UV protection GO:0009650 19 11 0,000 0,02205914 0,04540144 ! adult heart development GO:0007512 14 11 0,000 0,02205914 0,04536263 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02205914 0,04532389 ! temperature homeostasis GO:0001659 17 11 0,000 0,02205914 0,04528522 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02205914 0,04524662 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02205914 0,04520807 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02205914 0,0451696 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02205914 0,04513119 ! regulation of organ growth GO:0046620 13 11 0,000 0,02205914 0,04509285 ! pigment granule localization GO:0051875 20 11 0,000 0,02205914 0,04505457 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02205914 0,04501635 ! vasoconstriction GO:0042310 18 11 0,000 0,02205914 0,0449782 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02205914 0,04494012 ! embryonic axis specification GO:0000578 18 11 0,000 0,02205914 0,0449021 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02205914 0,04486414 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02205914 0,04482625 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02205914 0,04478842 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02205914 0,04475066 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02205914 0,04471296 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02205914 0,04467532 ! zymogen activation GO:0031638 15 11 0,000 0,02205914 0,04463775 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02205914 0,04460024 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02205914 0,04456279 ! nucleosome positioning GO:0016584 15 11 0,000 0,02205914 0,0445254 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02205914 0,04448808 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02205914 0,04445082 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02205914 0,04441362 ! acid secretion GO:0046717 18 11 0,000 0,02205914 0,04437649 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02205914 0,04433941 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02205914 0,0443024 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02205914 0,04426545 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02205914 0,04422857 ! oocyte differentiation GO:0009994 18 11 0,000 0,02205914 0,04419174 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02205914 0,04415497 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02205914 0,04411827 ! cholesterol efflux GO:0033344 19 11 0,000 0,02205914 0,04408163 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02205914 0,04404505 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02205914 0,04400852 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02205914 0,04397206 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02205914 0,04393566 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02205914 0,04389932 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02205914 0,04386304 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02205914 0,04382682 ! defense response to fungus GO:0050832 13 11 0,000 0,02205914 0,04379066 ! lysogeny GO:0030069 21 11 0,000 0,02205914 0,04375456 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02205914 0,04371852 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02205914 0,04368253 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02205914 0,04364661 ! regulation of embryonic development GO:0045995 27 11 0,000 0,02205914 0,04361075 ! nucleus localization GO:0051647 19 11 0,000 0,02205914 0,04357494 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02205914 0,0435392 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02404061 0,04741124 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02404061 0,04737241 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02404061 0,04733365 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,02404061 0,04729494 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02404061 0,0472563 ! virus-host interaction GO:0019048 29 12 0,000 0,02404061 0,04721773 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,02404061 0,04717921 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02404061 0,04714076 ! cartilage condensation GO:0001502 20 12 0,000 0,02404061 0,04710238 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02404061 0,04706405 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02404061 0,04702579 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02404061 0,04698758 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02404061 0,04694945 ! hippocampus development GO:0021766 26 12 0,000 0,02404061 0,04691137 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02404061 0,04687335 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02404061 0,0468354 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02404061 0,04679751 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02404061 0,04675967 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02404061 0,0467219 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02404061 0,04668419 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02404061 0,04664655 ! drug transport GO:0015893 16 12 0,000 0,02404061 0,04660896 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02404061 0,04657143 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02404061 0,04653396 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02404061 0,04649656 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02404061 0,04645921 ! focal adhesion formation GO:0048041 35 12 0,000 0,02404061 0,04642192 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02404061 0,0463847 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02404061 0,04634753 ! forebrain cell migration GO:0021885 21 12 0,000 0,02404061 0,04631042 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02404061 0,04627337 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,02404061 0,04623638 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02404061 0,04619945 ! fear response GO:0042596 26 12 0,000 0,02404061 0,04616258 ! monoamine transport GO:0015844 18 12 0,000 0,02404061 0,04612577 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02404061 0,04608902 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02404061 0,04605232 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02404061 0,04601569 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02404061 0,04597911 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02404061 0,04594259 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02404061 0,04590612 ! protein homotetramerization GO:0051289 21 12 0,000 0,02404061 0,04586972 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02404061 0,04583337 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02404061 0,04579708 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02404061 0,04576085 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02404061 0,04572468 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02404061 0,04568856 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02404061 0,0456525 ! fucose catabolic process GO:0019317 22 12 0,000 0,02404061 0,0456165 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02404061 0,04558055 ! histone acetylation GO:0016573 26 12 0,000 0,02404061 0,04554466 ! histone methylation GO:0016571 26 12 0,000 0,02404061 0,04550883 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02404061 0,04547305 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02404061 0,04543733 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02404061 0,04540166 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02404061 0,04536605 ! T cell homeostasis GO:0043029 25 12 0,000 0,02404061 0,0453305 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02404061 0,045295 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02404061 0,04525956 ! spleen development GO:0048536 22 12 0,000 0,02404061 0,04522417 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02404061 0,04518884 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02404061 0,04515357 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02404061 0,04511834 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02404061 0,04508318 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02404061 0,04504807 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,02404061 0,04501301 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02404061 0,04497801 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02404061 0,04494306 ! response to cold GO:0009409 17 12 0,000 0,02404061 0,04490817 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02404061 0,04487333 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02404061 0,04483854 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02601814 0,04848927 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,02601814 0,04845174 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02601814 0,04841427 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02601814 0,04837686 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,02601814 0,0483395 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,02601814 0,0483022 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,02601814 0,04826496 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,02601814 0,04822778 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,02601814 0,04819065 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,02601814 0,04815358 ! endocrine pancreas development GO:0031018 22 13 0,000 0,02601814 0,04811657 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,02601814 0,04807961 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,02601814 0,04804271 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,02601814 0,04800587 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02601814 0,04796908 ! methionine metabolic process GO:0006555 27 13 0,000 0,02601814 0,04793235 ! plasma membrane organization GO:0007009 24 13 0,000 0,02601814 0,04789568 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,02601814 0,04785906 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,02601814 0,0478225 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,02601814 0,04778599 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,02601814 0,04774954 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,02601814 0,04771315 ! response to X-ray GO:0010165 25 13 0,000 0,02601814 0,04767681 ! cytokine metabolic process GO:0042107 22 13 0,000 0,02601814 0,04764053 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,02601814 0,0476043 ! exocrine system development GO:0035272 32 13 0,000 0,02601814 0,04756813 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,02601814 0,04753201 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,02601814 0,04749594 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,02601814 0,04745993 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,02601814 0,04742398 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,02601814 0,04738808 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,02601814 0,04735223 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,02601814 0,04731644 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,02601814 0,0472807 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,02601814 0,04724502 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,02601814 0,04720939 ! regulation of cellular pH GO:0030641 22 13 0,000 0,02601814 0,04717382 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02601814 0,04713829 ! ribosome assembly GO:0042255 17 13 0,000 0,02601814 0,04710282 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,02601814 0,04706741 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,02601814 0,04703205 ! chromatin silencing GO:0006342 26 13 0,000 0,02601814 0,04699674 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,02601814 0,04696148 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02601814 0,04692628 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02601814 0,04689113 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,02601814 0,04685603 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,02601814 0,04682098 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,02601814 0,04678599 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02601814 0,04675105 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,02601814 0,04671616 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,02601814 0,04668132 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,02601814 0,04664654 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,02601814 0,0466118 ! embryonic placenta development GO:0001892 23 13 0,000 0,02601814 0,04657712 ! insulin secretion GO:0030073 23 13 0,000 0,02601814 0,04654249 ! actin filament polymerization GO:0030041 24 13 0,000 0,02601814 0,04650791 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,02601814 0,04647339 ! acrosome reaction GO:0007340 18 13 0,000 0,02601814 0,04643891 ! rRNA transcription GO:0009303 25 14 0,000 0,02799173 0,04992447 ! lactation GO:0007595 26 14 0,000 0,02799173 0,04988749 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,02799173 0,04985056 ! reproductive cellular process GO:0048610 20 14 0,000 0,02799173 0,04981369 ! tRNA modification GO:0006400 20 14 0,000 0,02799173 0,04977687 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,02799173 0,04974011 ! regulation of S phase GO:0033261 23 14 0,000 0,02799173 0,0497034 ! water transport GO:0006833 21 14 0,000 0,02799173 0,04966674 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,02799173 0,04963014 ! non-recombinational repair GO:0000726 25 14 0,000 0,02799173 0,0495936 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,02799173 0,0495571 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,02799173 0,04952067 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,02799173 0,04948428 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,02799173 0,04944795 ! RNA polyadenylation GO:0043631 30 14 0,000 0,02799173 0,04941167 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,02799173 0,04937544 ! palate development GO:0060021 31 14 0,000 0,02799173 0,04933927 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,02799173 0,04930315 ! regulated secretory pathway GO:0045055 23 14 0,000 0,02799173 0,04926709 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,02799173 0,04923107 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,02799173 0,04919511 ! arginine metabolic process GO:0006525 17 14 0,000 0,02799173 0,0491592 ! regulation of heart rate GO:0002027 24 14 0,000 0,02799173 0,04912334 ! organic alcohol transport GO:0015850 29 14 0,000 0,02799173 0,04908754 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,02799173 0,04905179 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,02799173 0,04901609 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,02799173 0,04898044 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02799173 0,04894484 ! neutral amino acid transport GO:0015804 26 14 0,000 0,02799173 0,0489093 ! L-amino acid transport GO:0015807 30 14 0,000 0,02799173 0,04887381 ! bone mineralization GO:0030282 17 14 0,000 0,02799173 0,04883837 ! stem cell development GO:0048864 43 14 0,000 0,02799173 0,04880298 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,02799173 0,04876764 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,02799173 0,04873235 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,02799173 0,04869711 ! cerebellum development GO:0021549 21 14 0,000 0,02799173 0,04866193 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,02799173 0,04862679 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,02799173 0,04859171 ! response to gamma radiation GO:0010332 28 14 0,000 0,02799173 0,04855667 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,02799173 0,04852169 ! cofactor transport GO:0051181 26 14 0,000 0,02799173 0,04848676 ! NADP metabolic process GO:0006739 24 14 0,000 0,02799173 0,04845187 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,02799173 0,04841704 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,02799173 0,04838226 ! intestinal absorption GO:0050892 25 14 0,000 0,02799173 0,04834753 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,02799173 0,04831284 ! oxygen transport GO:0015671 21 14 0,000 0,02799173 0,04827821 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02799173 0,04824363 ! male genitalia development GO:0030539 24 14 0,000 0,02799173 0,04820909 ! regulation of RNA stability GO:0043487 32 14 0,000 0,02799173 0,04817461 ! regulation of axon extension GO:0030516 37 14 0,000 0,02799173 0,04814018 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,02799173 0,04810579 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,02799173 0,04807145 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,02996139 0,05141733 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,02996139 0,05138068 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,02996139 0,05134408 ! superoxide anion generation GO:0042554 20 15 0,000 0,02996139 0,05130754 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,02996139 0,05127105 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,02996139 0,05123461 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,02996139 0,05119822 ! copper ion transport GO:0006825 20 15 0,000 0,02996139 0,05116188 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,02996139 0,0511256 ! sulfate transport GO:0008272 23 15 0,000 0,02996139 0,05108936 ! response to cAMP GO:0051591 22 15 0,000 0,02996139 0,05105318 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,02996139 0,05101705 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,02996139 0,05098097 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,02996139 0,05094494 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,02996139 0,05090896 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,02996139 0,05087304 ! response to hexose stimulus GO:0009746 22 15 0,000 0,02996139 0,05083716 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,02996139 0,05080133 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,02996139 0,05076556 ! pituitary gland development GO:0021983 29 15 0,000 0,02996139 0,05072983 ! vesicle coating GO:0006901 33 15 0,000 0,02996139 0,05069416 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,02996139 0,05065853 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,02996139 0,05062296 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,02996139 0,05058743 ! regulation of exocytosis GO:0017157 22 15 0,000 0,02996139 0,05055196 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,02996139 0,05051653 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,02996139 0,05048116 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,02996139 0,05044583 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,02996139 0,05041056 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,02996139 0,05037533 ! histone deacetylation GO:0016575 20 15 0,000 0,02996139 0,05034015 ! mRNA splice site selection GO:0006376 38 15 0,000 0,02996139 0,05030502 ! tissue regeneration GO:0042246 26 15 0,000 0,02996139 0,05026994 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,02996139 0,05023491 ! water homeostasis GO:0030104 27 15 0,000 0,02996139 0,05019993 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,02996139 0,05016499 ! muscle maintenance GO:0046716 26 15 0,000 0,02996139 0,05013011 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,02996139 0,05009527 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,02996139 0,05006048 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,02996139 0,05002574 ! dopamine metabolic process GO:0042417 35 15 0,000 0,02996139 0,04999105 ! heme biosynthetic process GO:0006783 29 15 0,000 0,02996139 0,04995641 ! cell killing GO:0001906 29 15 0,000 0,02996139 0,04992181 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,02996139 0,04988726 ! detection of bacterium GO:0016045 18 15 0,000 0,02996139 0,04985276 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,02996139 0,04981831 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,02996139 0,0497839 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,02996139 0,04974955 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,02996139 0,04971524 ! peptide hormone processing GO:0016486 23 15 0,000 0,02996139 0,04968097 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03192711 0,05290402 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03192711 0,05286761 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,03192711 0,05283125 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03192711 0,05279494 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03192711 0,05275868 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03192711 0,05272247 ! bone remodeling GO:0046849 27 16 0,000 0,03192711 0,05268631 ! filopodium assembly GO:0046847 32 16 0,000 0,03192711 0,0526502 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03192711 0,05261413 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03192711 0,05257812 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03192711 0,05254216 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03192711 0,05250624 ! startle response GO:0001964 28 16 0,000 0,03192711 0,05247038 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03192711 0,05243456 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03192711 0,0523988 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,03192711 0,05236308 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03192711 0,05232741 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03192711 0,05229179 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03192711 0,05225622 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03192711 0,05222069 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03192711 0,05218521 ! response to osmotic stress GO:0006970 25 16 0,000 0,03192711 0,05214979 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03192711 0,05211441 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03192711 0,05207908 ! fructose metabolic process GO:0006000 25 16 0,000 0,03192711 0,05204379 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03192711 0,05200856 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03192711 0,05197337 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03192711 0,05193823 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03192711 0,05190313 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03192711 0,05186809 ! axon cargo transport GO:0008088 43 16 0,000 0,03192711 0,05183309 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03192711 0,05179814 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03192711 0,05176323 ! DNA replication initiation GO:0006270 27 16 0,000 0,03192711 0,05172837 ! neuron recognition GO:0008038 35 16 0,000 0,03192711 0,05169356 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03192711 0,0516588 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03192711 0,05162408 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03192711 0,05158941 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03192711 0,05155479 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03192711 0,05152021 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03192711 0,05148568 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03192711 0,0514512 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03192711 0,05141676 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03192711 0,05138237 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03192711 0,05134802 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03192711 0,05131372 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,03192711 0,05127946 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03192711 0,05124525 ! defense response to virus GO:0051607 37 16 0,000 0,03192711 0,05121109 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,03388892 0,05432162 ! metencephalon development GO:0022037 30 17 0,000 0,03388892 0,05428545 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,03388892 0,05424934 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,03388892 0,05421327 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,03388892 0,05417724 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,03388892 0,05414127 ! endothelial cell migration GO:0043542 28 17 0,000 0,03388892 0,05410534 ! inositol metabolic process GO:0006020 28 17 0,000 0,03388892 0,05406946 ! gene silencing by RNA GO:0031047 36 17 0,000 0,03388892 0,05403363 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,03388892 0,05399785 ! glial cell development GO:0021782 27 17 0,000 0,03388892 0,05396211 ! limbic system development GO:0021761 36 17 0,000 0,03388892 0,05392642 ! adult walking behavior GO:0007628 33 17 0,000 0,03388892 0,05389078 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,03388892 0,05385519 ! heart looping GO:0001947 30 17 0,000 0,03388892 0,05381964 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,03388892 0,05378414 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,03388892 0,05374868 ! myoblast differentiation GO:0045445 45 17 0,000 0,03388892 0,05371328 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,03388892 0,05367791 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,03388892 0,0536426 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,03388892 0,05360733 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,03388892 0,05357211 ! glycine metabolic process GO:0006544 28 17 0,000 0,03388892 0,05353693 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,03388892 0,05350181 ! NAD metabolic process GO:0019674 29 17 0,000 0,03388892 0,05346672 ! membrane budding GO:0006900 37 17 0,000 0,03388892 0,05343169 ! DNA integration GO:0015074 29 17 0,000 0,03388892 0,05339669 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,03388892 0,05336175 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,03388892 0,05332685 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,03388892 0,05329199 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,03388892 0,05325719 ! genitalia development GO:0048806 30 17 0,000 0,03388892 0,05322242 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,03388892 0,0531877 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,03388892 0,05315303 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,03388892 0,0531184 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,03388892 0,05308382 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,03388892 0,05304929 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,03388892 0,05301479 ! steroid catabolic process GO:0006706 31 17 0,000 0,03388892 0,05298035 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,03388892 0,05294594 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,03388892 0,05291158 ! gas transport GO:0015669 25 17 0,000 0,03388892 0,05287727 ! organic cation transport GO:0015695 31 17 0,000 0,03388892 0,052843 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,03388892 0,05280878 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,03388892 0,0527746 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,03388892 0,05274046 ! microspike assembly GO:0030035 36 17 0,000 0,03388892 0,05270637 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,03388892 0,05267232 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,03388892 0,05263832 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,03584682 0,05564352 ! neuron maturation GO:0042551 42 18 0,000 0,03584682 0,05560765 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,03584682 0,05557182 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,03584682 0,05553603 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,03584682 0,05550029 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,03584682 0,0554646 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,03584682 0,05542896 ! memory GO:0007613 31 18 0,000 0,03584682 0,05539336 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03584682 0,0553578 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,03584682 0,05532229 ! patterning of blood vessels GO:0001569 39 18 0,000 0,03584682 0,05528683 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,03584682 0,05525141 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,03584682 0,05521604 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,03584682 0,05518072 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,03584682 0,05514543 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03584682 0,0551102 ! response to retinoic acid GO:0032526 26 18 0,000 0,03584682 0,055075 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,03584682 0,05503986 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,03584682 0,05500476 ! response to fungus GO:0009620 21 18 0,000 0,03584682 0,0549697 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,03584682 0,05493469 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,03584682 0,05489972 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,03584682 0,05486479 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,03584682 0,05482992 ! vitamin transport GO:0051180 27 18 0,000 0,03584682 0,05479508 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,03584682 0,05476029 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,03584682 0,05472554 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,03584682 0,05469084 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,03584682 0,05465618 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,03584682 0,05462157 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,03584682 0,054587 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,03584682 0,05455247 ! protein secretion GO:0009306 39 19 0,000 0,03780082 0,05748974 ! positive regulation of translation GO:0045727 30 19 0,000 0,03780082 0,05745343 ! negative regulation of defense response GO:0031348 25 19 0,000 0,03780082 0,05741716 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,03780082 0,05738093 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,03780082 0,05734475 ! skin development GO:0043588 36 19 0,000 0,03780082 0,05730862 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,03780082 0,05727253 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03780082 0,05723648 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,03780082 0,05720049 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,03780082 0,05716453 ! bile acid metabolic process GO:0008206 29 19 0,000 0,03780082 0,05712863 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,03780082 0,05709276 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,03780082 0,05705695 ! cerebral cortex development GO:0021987 36 19 0,000 0,03780082 0,05702117 ! pigmentation during development GO:0048066 41 19 0,000 0,03780082 0,05698545 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,03780082 0,05694976 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,03780082 0,05691413 ! heme metabolic process GO:0042168 36 19 0,000 0,03780082 0,05687853 ! actin filament bundle formation GO:0051017 42 19 0,000 0,03780082 0,05684298 ! neuromuscular junction development GO:0007528 34 19 0,000 0,03780082 0,05680748 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,03780082 0,05677202 ! plasma membrane fusion GO:0045026 28 19 0,000 0,03780082 0,0567366 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,03780082 0,05670123 ! peptide cross-linking GO:0018149 37 19 0,000 0,03780082 0,0566659 ! protein export from nucleus GO:0006611 36 19 0,000 0,03780082 0,05663062 ! heart process GO:0003015 30 19 0,000 0,03780082 0,05659538 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,03780082 0,05656018 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,03780082 0,05652503 ! cellular pigmentation GO:0033059 36 19 0,000 0,03780082 0,05648992 ! G1 phase GO:0051318 40 19 0,000 0,03780082 0,05645486 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,03780082 0,05641983 ! cell-cell junction organization GO:0045216 35 19 0,000 0,03780082 0,05638486 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,03780082 0,05634992 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,03780082 0,05631503 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,03780082 0,05628018 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,03780082 0,05624538 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,03780082 0,05621061 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,03780082 0,05617589 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,03780082 0,05614122 ! cilium assembly GO:0042384 37 19 0,000 0,03780082 0,05610658 ! peptide hormone secretion GO:0030072 31 19 0,000 0,03780082 0,05607199 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,03975092 0,05892835 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,03975092 0,05889207 ! positive regulation of ossification GO:0045778 47 20 0,000 0,03975092 0,05885583 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,03975092 0,05881963 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,03975092 0,05878348 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,03975092 0,05874737 ! cAMP metabolic process GO:0046058 36 20 0,000 0,03975092 0,05871131 ! response to vitamin GO:0033273 31 20 0,000 0,03975092 0,05867529 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,03975092 0,05863931 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,03975092 0,05860338 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,03975092 0,05856749 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,03975092 0,05853165 ! response to alkaloid GO:0043279 38 20 0,000 0,03975092 0,05849585 ! retinoid metabolic process GO:0001523 32 20 0,000 0,03975092 0,0584601 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,03975092 0,05842438 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,03975092 0,05838872 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,03975092 0,05835309 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,03975092 0,05831751 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,03975092 0,05828197 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,03975092 0,05824648 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,03975092 0,05821103 ! body fluid secretion GO:0007589 31 20 0,000 0,03975092 0,05817562 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,03975092 0,05814025 ! peptide secretion GO:0002790 35 20 0,000 0,03975092 0,05810493 ! stem cell differentiation GO:0048863 53 20 0,000 0,03975092 0,05806965 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,03975092 0,05803442 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,03975092 0,05799922 ! sensory perception of pain GO:0019233 30 20 0,000 0,03975092 0,05796407 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,03975092 0,05792896 ! diencephalon development GO:0021536 34 20 0,000 0,03975092 0,0578939 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,03975092 0,05785887 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,03975092 0,05782389 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,03975092 0,05778895 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,03975092 0,05775406 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,03975092 0,0577192 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,03975092 0,05768439 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,03975092 0,05764962 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,03975092 0,05761489 ! regulation of glucose import GO:0046324 29 20 0,000 0,03975092 0,0575802 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,03975092 0,05754556 ! actin filament-based movement GO:0030048 43 20 0,000 0,03975092 0,05751095 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,03975092 0,05747639 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,03975092 0,05744187 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,03975092 0,05740739 ! negative regulation of translation GO:0017148 29 20 0,000 0,03975092 0,05737296 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,03975092 0,05733856 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,03975092 0,0573042 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,04169714 0,06007384 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,04169714 0,06003789 ! hormone secretion GO:0046879 38 21 0,000 0,04169714 0,06000198 ! glycerol metabolic process GO:0006071 34 21 0,000 0,04169714 0,05996611 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,04169714 0,05993029 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,04169714 0,05989451 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,04169714 0,05985878 ! axis specification GO:0009798 38 21 0,000 0,04169714 0,05982308 ! ovarian follicle development GO:0001541 35 21 0,000 0,04169714 0,05978743 ! smooth muscle contraction GO:0006939 46 21 0,000 0,04169714 0,05975182 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,04169714 0,05971625 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,04169714 0,05968073 ! cell aging GO:0007569 44 21 0,000 0,04169714 0,05964525 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,04169714 0,05960981 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,04169714 0,05957441 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,04169714 0,05953905 ! cytolysis GO:0019835 24 21 0,000 0,04169714 0,05950374 ! vasodilation GO:0042311 39 21 0,000 0,04169714 0,05946847 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,04169714 0,05943324 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,04169714 0,05939805 ! oogenesis GO:0048477 36 21 0,000 0,04169714 0,0593629 ! DNA modification GO:0006304 34 21 0,000 0,04169714 0,0593278 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,04169714 0,05929273 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,04169714 0,05925771 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,04169714 0,05922273 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,04169714 0,05918779 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,04169714 0,05915289 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,04169714 0,05911804 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,04169714 0,05908322 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,04169714 0,05904844 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,04169714 0,05901371 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,04169714 0,05897902 ! collagen catabolic process GO:0030574 28 21 0,000 0,04169714 0,05894436 ! sperm-egg recognition GO:0035036 21 21 0,000 0,04169714 0,05890975 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,04363947 0,0616177 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,04363947 0,06158156 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,04363947 0,06154546 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,04363947 0,06150941 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,04363947 0,0614734 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,04363947 0,06143743 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,04363947 0,0614015 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,04363947 0,06136561 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,04363947 0,06132977 ! regeneration GO:0031099 41 22 0,000 0,04363947 0,06129397 ! keratinization GO:0031424 28 22 0,000 0,04363947 0,0612582 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,04363947 0,06122249 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,04363947 0,06118681 ! sensory perception of taste GO:0050909 28 22 0,000 0,04363947 0,06115117 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,04363947 0,06111558 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,04363947 0,06108002 ! vacuolar transport GO:0007034 36 22 0,000 0,04363947 0,06104451 ! lysosome organization GO:0007040 41 22 0,000 0,04363947 0,06100904 ! central nervous system neuron development GO:0021954 46 22 0,000 0,04363947 0,06097361 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,04363947 0,06093823 ! fucose metabolic process GO:0006004 39 22 0,000 0,04363947 0,06090288 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,04363947 0,06086757 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,04363947 0,06083231 ! ureteric bud development GO:0001657 43 22 0,000 0,04363947 0,06079708 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,04363947 0,0607619 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,04363947 0,06072676 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,04363947 0,06069165 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,04363947 0,06065659 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,04363947 0,06062157 ! sarcomere organization GO:0045214 30 22 0,000 0,04363947 0,06058659 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,04363947 0,06055165 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,04363947 0,06051675 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,04363947 0,06048189 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,04363947 0,06044707 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,04363947 0,06041229 ! protein stabilization GO:0050821 39 22 0,000 0,04363947 0,06037755 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,04557793 0,06302328 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,04557793 0,06298708 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,04557793 0,06295092 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,04557793 0,0629148 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,04557793 0,06287873 ! gluconeogenesis GO:0006094 33 23 0,000 0,04557793 0,06284269 ! viral genome replication GO:0019079 41 23 0,000 0,04557793 0,0628067 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,04557793 0,06277075 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,04557793 0,06273484 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,04557793 0,06269897 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,04557793 0,06266314 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,04557793 0,06262736 ! visual behavior GO:0007632 42 23 0,000 0,04557793 0,06259161 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,04557793 0,0625559 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,04557793 0,06252024 ! response to ethanol GO:0045471 46 23 0,000 0,04557793 0,06248462 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,04557793 0,06244903 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,04557793 0,06241349 ! peroxisome organization GO:0007031 37 23 0,000 0,04557793 0,06237799 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,04557793 0,06234252 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,04557793 0,0623071 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,04557793 0,06227172 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,04557793 0,06223638 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,04557793 0,06220108 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,04557793 0,06216582 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,04557793 0,0621306 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,04557793 0,06209541 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,04557793 0,06206027 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,04557793 0,06202517 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,04557793 0,06199011 ! fatty acid transport GO:0015908 44 23 0,000 0,04557793 0,06195508 ! platelet activation GO:0030168 37 23 0,000 0,04557793 0,0619201 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,04557793 0,06188516 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,04557793 0,06185025 ! hormone transport GO:0009914 40 23 0,000 0,04557793 0,06181539 ! cell-cell recognition GO:0009988 25 23 0,000 0,04557793 0,06178056 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,04557793 0,06174578 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,04557793 0,06171103 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,04557793 0,06167632 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,04557793 0,06164165 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,04557793 0,06160702 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,04751253 0,06418593 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,04751253 0,06414991 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,04751253 0,06411393 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,04751253 0,06407799 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,04751253 0,06404209 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,04751253 0,06400624 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,04751253 0,06397042 ! spinal cord development GO:0021510 47 24 0,000 0,04751253 0,06393464 ! vacuole organization GO:0007033 43 24 0,000 0,04751253 0,0638989 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,04751253 0,06386321 ! digestive system process GO:0022600 39 24 0,000 0,04751253 0,06382755 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,04751253 0,06379193 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,04751253 0,06375635 ! regulation of behavior GO:0050795 43 24 0,000 0,04751253 0,06372081 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,04751253 0,06368531 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,04751253 0,06364985 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,04751253 0,06361443 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,04751253 0,06357905 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,04751253 0,06354371 ! pallium development GO:0021543 49 24 0,000 0,04751253 0,06350841 ! pentose metabolic process GO:0019321 35 24 0,000 0,04751253 0,06347315 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,04751253 0,06343792 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,04751253 0,06340274 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,04751253 0,06336759 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,04751253 0,06333249 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,04751253 0,06329742 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,04751253 0,06326239 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,04751253 0,0632274 ! regulation of amine transport GO:0051952 40 24 0,000 0,04751253 0,06319245 ! protein tetramerization GO:0051262 52 24 0,000 0,04751253 0,06315754 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,04944327 0,06568774 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,04944327 0,06565149 ! myelination GO:0042552 45 25 0,000 0,04944327 0,06561528 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,04944327 0,06557911 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,04944327 0,06554297 ! phototransduction GO:0007602 33 25 0,000 0,04944327 0,06550688 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,04944327 0,06547083 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,04944327 0,06543482 ! sperm motility GO:0030317 31 25 0,000 0,04944327 0,06539884 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,04944327 0,06536291 ! receptor metabolic process GO:0043112 46 25 0,000 0,04944327 0,06532702 ! chromosome condensation GO:0030261 45 25 0,000 0,04944327 0,06529116 ! response to starvation GO:0042594 42 25 0,000 0,04944327 0,06525535 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,04944327 0,06521957 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,04944327 0,06518383 ! negative regulation of cell development GO:0010721 73 25 0,000 0,04944327 0,06514814 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,04944327 0,06511248 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,04944327 0,06507686 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,04944327 0,06504128 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,04944327 0,06500574 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,04944327 0,06497023 ! immunoglobulin production GO:0002377 55 25 0,000 0,04944327 0,06493477 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,04944327 0,06489934 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,04944327 0,06486396 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,04944327 0,06482861 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,04944327 0,0647933 ! telomere organization GO:0032200 43 25 0,000 0,04944327 0,06475803 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,04944327 0,0647228 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,04944327 0,0646876 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,05137016 0,06717206 ! embryonic pattern specification GO:0009880 44 26 0,000 0,05137016 0,06713558 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,05137016 0,06709913 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,05137016 0,06706272 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,05137016 0,06702635 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,05137016 0,06699002 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,05137016 0,06695373 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,05137016 0,06691748 ! molting cycle process GO:0022404 50 26 0,000 0,05137016 0,06688127 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,05137016 0,0668451 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,05137016 0,06680897 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,05137016 0,06677288 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,05137016 0,06673682 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,05137016 0,06670081 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,05137016 0,06666483 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,05137016 0,06662889 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,05137016 0,06659299 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,05137016 0,06655713 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,05137016 0,06652131 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,05137016 0,06648553 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,05137016 0,06644978 ! blastocyst development GO:0001824 49 26 0,000 0,05137016 0,06641408 ! leukocyte proliferation GO:0070661 52 26 0,000 0,05137016 0,06637841 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,05137016 0,06634278 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,05137016 0,06630719 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,0532932 0,06875252 ! neuron fate commitment GO:0048663 48 27 0,000 0,0532932 0,06871567 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,0532932 0,06867887 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,0532932 0,0686421 ! iron ion transport GO:0006826 59 27 0,000 0,0532932 0,06860538 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,0532932 0,06856869 ! protein amino acid acylation GO:0043543 55 27 0,000 0,0532932 0,06853204 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,0532932 0,06849543 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,0532932 0,06845886 ! fat cell differentiation GO:0045444 50 27 0,000 0,0532932 0,06842233 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,0532932 0,06838584 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,0532932 0,06834939 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,0532932 0,06831297 ! autophagy GO:0006914 41 27 0,000 0,0532932 0,0682766 ! response to toxin GO:0009636 47 27 0,000 0,0532932 0,06824026 ! primary neural tube formation GO:0014020 51 27 0,000 0,0532932 0,06820396 ! base-excision repair GO:0006284 41 27 0,000 0,0532932 0,0681677 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,0532932 0,06813148 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,0532932 0,0680953 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,0532932 0,06805915 ! glutathione metabolic process GO:0006749 39 27 0,000 0,0532932 0,06802305 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,0532932 0,06798698 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,0532932 0,06795095 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,0532932 0,06791496 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,0532932 0,06787901 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,05521242 0,07028628 ! circadian rhythm GO:0007623 50 28 0,000 0,05521242 0,07024911 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,05521242 0,07021198 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,05521242 0,07017489 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,05521242 0,07013784 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,05521242 0,07010083 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,05521242 0,07006386 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,05521242 0,07002692 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,05521242 0,06999003 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,05521242 0,06995317 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,05521242 0,06991635 ! synaptogenesis GO:0007416 42 28 0,000 0,05521242 0,06987958 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,05521242 0,06984284 ! lipid oxidation GO:0034440 43 28 0,000 0,05521242 0,06980613 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,05521242 0,06976947 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,05521242 0,06973285 ! translational initiation GO:0006413 65 29 0,000 0,0571278 0,07211411 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,0571278 0,07207629 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,0571278 0,07203852 ! regulation of pH GO:0006885 43 29 0,000 0,0571278 0,07200078 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,0571278 0,07196308 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,0571278 0,07192543 ! catechol metabolic process GO:0009712 54 29 0,000 0,0571278 0,07188781 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,0571278 0,07185023 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,0571278 0,07181269 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,0571278 0,07177519 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,0571278 0,07173773 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,0571278 0,07170031 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,0571278 0,07166293 ! cell fate determination GO:0001709 60 29 0,000 0,0571278 0,07162558 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,0571278 0,07158828 ! detection of light stimulus GO:0009583 38 29 0,000 0,0571278 0,07155101 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,0571278 0,07151378 ! tissue homeostasis GO:0001894 48 29 0,000 0,0571278 0,07147659 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,05903937 0,0738299 ! zinc ion transport GO:0006829 45 30 0,000 0,05903937 0,07379154 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,05903937 0,07375323 ! cell junction assembly GO:0034329 78 30 0,000 0,05903937 0,07371496 ! regulation of innate immune response GO:0045088 51 30 0,000 0,05903937 0,07367672 ! acute-phase response GO:0006953 49 30 0,000 0,05903937 0,07363853 ! myofibril assembly GO:0030239 47 30 0,000 0,05903937 0,07360037 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,05903937 0,07356226 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,05903937 0,07352418 ! phospholipid transport GO:0015914 51 30 0,000 0,05903937 0,07348615 ! ensheathment of neurons GO:0007272 57 30 0,000 0,05903937 0,07344815 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,05903937 0,07341019 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,05903937 0,07337227 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,05903937 0,07333439 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,05903937 0,07329655 ! eye morphogenesis GO:0048592 60 30 0,000 0,05903937 0,07325875 ! regulation of B cell activation GO:0050864 50 30 0,000 0,05903937 0,07322099 ! response to heat GO:0009408 50 30 0,000 0,05903937 0,07318327 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,06094712 0,07550915 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,06094712 0,07547029 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,06094712 0,07543147 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,06094712 0,07539269 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,06094712 0,07535394 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,06094712 0,07531524 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,06094712 0,07527658 ! ovulation cycle process GO:0022602 49 31 0,000 0,06094712 0,07523796 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,06094712 0,07519937 ! peptide transport GO:0015833 55 31 0,000 0,06094712 0,07516083 ! iron ion homeostasis GO:0055072 54 31 0,000 0,06094712 0,07512232 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,06094712 0,07508386 ! mesoderm formation GO:0001707 69 31 0,000 0,06094712 0,07504543 ! natural killer cell activation GO:0030101 45 31 0,000 0,06094712 0,07500705 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,06094712 0,0749687 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,06094712 0,07493039 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,06094712 0,07489212 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,06094712 0,07485389 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,06094712 0,0748157 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,06285107 0,07711355 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,06285107 0,07707425 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,06285107 0,07703499 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,06285107 0,07699576 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,06285107 0,07695658 ! spliceosome assembly GO:0000245 67 32 0,000 0,06285107 0,07691744 ! spindle organization GO:0007051 46 32 0,000 0,06285107 0,07687833 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,06285107 0,07683927 ! metanephros development GO:0001656 74 32 0,000 0,06285107 0,07680024 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,06285107 0,07676126 ! response to ionizing radiation GO:0010212 65 32 0,000 0,06285107 0,07672231 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,06285107 0,07668341 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,06285107 0,07664454 ! muscle cell development GO:0055001 49 32 0,000 0,06285107 0,07660571 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,06285107 0,07656693 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,06285107 0,07652818 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,06285107 0,07648947 ! ovulation cycle GO:0042698 51 32 0,000 0,06285107 0,0764508 ! BMP signaling pathway GO:0030509 64 32 0,000 0,06285107 0,07641217 ! hindbrain development GO:0030902 61 32 0,000 0,06285107 0,07637357 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,06285107 0,07633502 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,06285107 0,07629651 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,06285107 0,07625803 ! gene silencing GO:0016458 65 32 0,000 0,06285107 0,0762196 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,06475122 0,07848435 ! post-embryonic development GO:0009791 69 33 0,000 0,06475122 0,07844484 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,06475122 0,07840536 ! protein targeting to membrane GO:0006612 68 33 0,000 0,06475122 0,07836592 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,06475122 0,07832652 ! ceramide metabolic process GO:0006672 64 33 0,000 0,06475122 0,07828716 ! formation of primary germ layer GO:0001704 72 33 0,000 0,06475122 0,07824784 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,06475122 0,07820856 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,06475122 0,07816931 ! adult locomotory behavior GO:0008344 59 33 0,000 0,06475122 0,07813011 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,06475122 0,07809095 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,06475122 0,07805183 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,06664759 0,08029749 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,06664759 0,0802573 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,06664759 0,08021716 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,06664759 0,08017705 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,06664759 0,08013698 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,06664759 0,08009695 ! mismatch repair GO:0006298 46 34 0,000 0,06664759 0,08005696 ! spermatid development GO:0007286 63 34 0,000 0,06664759 0,08001701 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,06664759 0,0799771 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,06664759 0,07993723 ! placenta development GO:0001890 53 34 0,000 0,06664759 0,07989741 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,06854017 0,08212532 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,06854017 0,08208444 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,06854017 0,0820436 ! odontogenesis GO:0042476 66 35 0,000 0,06854017 0,08200281 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,06854017 0,08196205 ! female gonad development GO:0008585 58 35 0,000 0,06854017 0,08192133 ! telencephalon development GO:0021537 68 35 0,000 0,06854017 0,08188066 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,06854017 0,08184002 ! cytokine production GO:0001816 59 35 0,000 0,06854017 0,08179943 ! neural tube formation GO:0001841 67 35 0,000 0,06854017 0,08175887 ! vesicle localization GO:0051648 64 35 0,000 0,06854017 0,08171836 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,07042897 0,08392873 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,07042897 0,08388718 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,07042897 0,08384567 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,07042897 0,08380421 ! cell junction organization GO:0034330 86 36 0,000 0,07042897 0,08376278 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,07042897 0,0837214 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,07042897 0,08368005 ! positive regulation of cell development GO:0010720 80 36 0,000 0,07042897 0,08363875 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,07042897 0,08359749 ! regulation of proteolysis GO:0030162 72 36 0,000 0,07042897 0,08355627 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,07042897 0,08351509 ! aerobic respiration GO:0009060 55 36 0,000 0,07042897 0,08347394 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,07042897 0,08343284 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,07042897 0,08339179 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,07042897 0,08335077 ! RNA export from nucleus GO:0006405 56 37 0,000 0,07231401 0,08553958 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,07231401 0,08549755 ! meiosis I GO:0007127 65 37 0,000 0,07231401 0,08545555 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,07231401 0,0854136 ! sister chromatid segregation GO:0000819 58 37 0,000 0,07231401 0,08537169 ! actomyosin structure organization GO:0031032 62 37 0,000 0,07231401 0,08532982 ! organic anion transport GO:0015711 68 37 0,000 0,07231401 0,085288 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,07231401 0,08524621 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,07231401 0,08520446 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,07231401 0,08516276 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,07231401 0,08512109 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,07231401 0,08507947 ! glycogen metabolic process GO:0005977 61 37 0,000 0,07231401 0,08503788 ! pigment metabolic process GO:0042440 80 37 0,000 0,07231401 0,08499634 ! spermatid differentiation GO:0048515 66 37 0,000 0,07231401 0,08495484 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,07419529 0,08712243 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,07419529 0,08707993 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,07419529 0,08703748 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,07419529 0,08699506 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,07419529 0,08695269 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,07419529 0,08691035 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,07419529 0,08686806 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,07419529 0,08682581 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,07419529 0,0867836 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,07419529 0,08674143 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,07419529 0,0866993 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,07419529 0,08665722 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,07419529 0,08661517 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,07419529 0,08657316 ! glucan metabolic process GO:0044042 62 38 0,000 0,07419529 0,0865312 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,07607281 0,0886779 ! learning GO:0007612 77 39 0,000 0,07607281 0,08863496 ! segmentation GO:0035282 67 39 0,000 0,07607281 0,08859206 ! ion transmembrane transport GO:0034220 66 39 0,000 0,07607281 0,0885492 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,07607281 0,08850638 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,07607281 0,0884636 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,07607281 0,08842087 ! RNA modification GO:0009451 57 39 0,000 0,07607281 0,08837817 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,07607281 0,08833552 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,07794659 0,09046768 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,07794659 0,09042406 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,07794659 0,09038048 ! feeding behavior GO:0007631 59 40 0,000 0,07794659 0,09033695 ! negative regulation of binding GO:0051100 72 40 0,000 0,07794659 0,09029346 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,07794659 0,09025 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,07794659 0,09020659 ! maintenance of protein location GO:0045185 91 40 0,000 0,07794659 0,09016322 ! cytokinesis GO:0000910 72 40 0,000 0,07794659 0,0901199 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,07981664 0,09223767 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,07981664 0,09219339 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,07981664 0,09214915 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,07981664 0,09210495 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,07981664 0,0920608 ! T cell differentiation GO:0030217 81 41 0,000 0,07981664 0,09201669 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,07981664 0,09197262 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,07981664 0,09192859 ! female gamete generation GO:0007292 61 41 0,000 0,07981664 0,09188461 ! polyol metabolic process GO:0019751 66 41 0,000 0,07981664 0,09184066 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,07981664 0,09179676 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,08168295 0,09389831 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,08168295 0,09385347 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,08168295 0,09380867 ! regulation of tube size GO:0035150 71 42 0,000 0,08168295 0,09376392 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,08168295 0,09371921 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,08168295 0,09367453 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,08168295 0,09362991 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,08168295 0,09358532 ! neuron migration GO:0001764 79 42 0,000 0,08168295 0,09354078 ! regulation of protein secretion GO:0050708 71 42 0,000 0,08168295 0,09349628 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,08168295 0,09345182 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,08354554 0,09553734 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,08354554 0,09549195 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,08354554 0,09544661 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,08354554 0,09540131 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,08354554 0,09535605 ! glucose transport GO:0015758 65 43 0,000 0,08354554 0,09531084 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,08354554 0,09526567 ! neural tube development GO:0021915 77 43 0,000 0,08354554 0,09522054 ! striated muscle contraction GO:0006941 77 43 0,000 0,08354554 0,09517545 ! phagocytosis GO:0006909 90 43 0,000 0,08354554 0,09513041 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,08354554 0,09508541 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,08540441 0,09715509 ! hexose transport GO:0008645 67 44 0,000 0,08540441 0,09710917 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,08540441 0,0970633 ! double-strand break repair GO:0006302 81 44 0,000 0,08540441 0,09701747 ! biopolymer methylation GO:0043414 84 44 0,000 0,08540441 0,09697169 ! B cell differentiation GO:0030183 107 44 0,000 0,08540441 0,09692595 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,08540441 0,09688025 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,08540441 0,09683459 ! developmental growth GO:0048589 82 44 0,000 0,08540441 0,09678898 ! maintenance of location in cell GO:0051651 97 44 0,000 0,08540441 0,09674341 ! glycolysis GO:0006096 65 45 0,000 0,08725957 0,09879837 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,08725957 0,0987519 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,08725957 0,09870547 ! induction of apoptosis by intracellular signals GO:0008629 93 45 0,000 0,08725957 0,09865908 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,08725957 0,09861274 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,08725957 0,09856645 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,08725957 0,09852019 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,08725957 0,09847398 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,08725957 0,09842782 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,08911103 0,10046914 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,08911103 0,10042208 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,08911103 0,10037507 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,08911103 0,1003281 ! pigmentation GO:0043473 100 46 0,000 0,08911103 0,10028117 ! positive regulation of defense response GO:0031349 76 47 0,000 0,0909588 0,10231271 ! response to calcium ion GO:0051592 81 47 0,000 0,0909588 0,1022649 ! endosome transport GO:0016197 108 47 0,000 0,0909588 0,10221713 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,0909588 0,10216941 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,0909588 0,10212173 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,0909588 0,1020741 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,0909588 0,10202652 ! JNK cascade GO:0007254 91 47 0,000 0,0909588 0,10197897 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,0909588 0,10193148 ! methylation GO:0032259 90 47 0,000 0,0909588 0,10188402 ! mitochondrial transport GO:0006839 82 48 0,000 0,09280288 0,10390123 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,09280288 0,1038529 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,09280288 0,10380462 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,09280288 0,10375638 ! activation of caspase activity GO:0006919 84 48 0,000 0,09280288 0,10370819 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,09280288 0,10366004 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,09280288 0,10361194 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,09280288 0,10356388 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,09464328 0,10556873 ! regulation of action potential GO:0001508 95 49 0,000 0,09464328 0,10551981 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,09464328 0,10547093 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,09464328 0,1054221 ! regulation of ion transport GO:0043269 77 49 0,000 0,09464328 0,10537332 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,09464328 0,10532458 ! peptide metabolic process GO:0006518 76 49 0,000 0,09464328 0,10527589 ! response to temperature stimulus GO:0009266 76 49 0,000 0,09464328 0,10522724 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,09464328 0,10517863 ! endocrine system development GO:0035270 104 49 0,000 0,09464328 0,10513007 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,09464328 0,10508156 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,09464328 0,10503309 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,09464328 0,10498467 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,09464328 0,10493629 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,09648001 0,1069235 ! neuromuscular process GO:0050905 99 50 0,000 0,09648001 0,10687427 ! regulation of ossification GO:0030278 117 50 0,000 0,09648001 0,10682509 ! histone modification GO:0016570 91 50 0,000 0,09648001 0,10677595 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,09648001 0,10672686 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,09648001 0,10667781 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,09648001 0,10662881 ! positive regulation of binding GO:0051099 78 51 0,000 0,09831308 0,1086048 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,09831308 0,10855496 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,09831308 0,10850517 ! excretion GO:0007588 83 51 0,000 0,09831308 0,10845542 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,09831308 0,10840571 ! chromatin remodeling GO:0006338 109 51 0,000 0,09831308 0,10835605 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,09831308 0,10830644 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,09831308 0,10825687 ! regulation of cell shape GO:0008360 125 51 0,000 0,09831308 0,10820735 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,09831308 0,10815787 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,10014248 0,11012011 ! positive regulation of growth GO:0045927 90 52 0,000 0,10014248 0,11006981 ! covalent chromatin modification GO:0016569 101 52 0,000 0,10014248 0,11001955 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,10014248 0,10996933 ! amino acid activation GO:0043038 92 52 0,000 0,10014248 0,10991917 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,10014248 0,10986904 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,10196824 0,11182114 ! RNA catabolic process GO:0006401 93 53 0,000 0,10196824 0,11177019 ! regulation of translational initiation GO:0006446 82 53 0,000 0,10196824 0,1117193 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,10196824 0,11166845 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,10196824 0,11161764 ! cell maturation GO:0048469 100 53 0,000 0,10196824 0,11156688 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,10379035 0,1135089 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,10379035 0,11345733 ! cell recognition GO:0008037 85 54 0,000 0,10379035 0,1134058 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,10379035 0,11335432 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,10379035 0,11330289 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,10379035 0,11325151 ! chloride transport GO:0006821 90 55 0,000 0,10560882 0,11518351 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,10560882 0,11513132 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,10560882 0,11507918 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,10560882 0,11502708 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,10560882 0,11497503 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,10560882 0,11492303 ! aging GO:0007568 103 55 0,000 0,10560882 0,11487108 ! gastrulation GO:0007369 112 55 0,000 0,10560882 0,11481917 ! heart morphogenesis GO:0003007 97 55 0,000 0,10560882 0,11476731 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,10560882 0,1147155 ! RNA elongation GO:0006354 79 55 0,000 0,10560882 0,11466373 ! nuclear export GO:0051168 97 55 0,000 0,10560882 0,11461201 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,10560882 0,11456034 ! sensory perception of smell GO:0007608 80 56 0,000 0,10742367 0,11647649 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,10742367 0,11642403 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,10742367 0,11637161 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,10742367 0,11631923 ! regulation of DNA replication GO:0006275 101 56 0,000 0,10742367 0,11626691 ! proton transport GO:0015992 94 56 0,000 0,10742367 0,11621463 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,10923489 0,11812096 ! muscle fiber development GO:0048747 112 57 0,000 0,10923489 0,1180679 ! maintenance of location GO:0051235 118 57 0,000 0,10923489 0,11801488 ! hydrogen transport GO:0006818 97 58 0,000 0,1110425 0,11991393 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,1110425 0,11986014 ! regulation of endocytosis GO:0030100 91 58 0,000 0,1110425 0,11980639 ! adult behavior GO:0030534 99 58 0,000 0,1110425 0,11975269 ! positive regulation of secretion GO:0051047 95 59 0,000 0,11284649 0,12164367 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,11284649 0,12158919 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,11284649 0,12153477 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,11284649 0,12148039 ! DNA catabolic process GO:0006308 86 59 0,000 0,11284649 0,12142606 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,11284649 0,12137178 ! establishment of organelle localization GO:0051656 109 59 0,000 0,11284649 0,12131754 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,11464689 0,12319805 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,11464689 0,12314305 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,11464689 0,1230881 ! regulation of heart contraction GO:0008016 110 60 0,000 0,11464689 0,12303319 ! camera-type eye development GO:0043010 116 60 0,000 0,11464689 0,12297834 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,11464689 0,12292354 ! kidney development GO:0001822 122 60 0,000 0,11464689 0,12286879 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,1164437 0,12473888 ! mesoderm development GO:0007498 119 61 0,000 0,1164437 0,12468337 ! tRNA processing GO:0008033 89 61 0,000 0,1164437 0,12462791 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,1164437 0,12457249 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,11823691 0,12643467 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,11823691 0,1263785 ! regulation of mitosis GO:0007088 105 63 0,000 0,12002655 0,12823441 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,12002655 0,12817749 ! detection of external stimulus GO:0009581 91 63 0,000 0,12002655 0,12812062 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,12002655 0,12806381 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,12002655 0,12800704 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,12181262 0,1298543 ! cell redox homeostasis GO:0045454 102 64 0,000 0,12181262 0,12979679 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,12181262 0,12973933 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,12181262 0,12968193 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,12359511 0,13152138 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,12359511 0,13146324 ! germ cell development GO:0007281 118 65 0,000 0,12359511 0,13140515 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,12359511 0,1313471 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,12537405 0,1331788 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,12537405 0,13312002 ! extracellular matrix organization GO:0030198 133 66 0,000 0,12537405 0,1330613 ! secondary metabolic process GO:0019748 116 66 0,000 0,12537405 0,13300263 ! developmental maturation GO:0021700 116 66 0,000 0,12537405 0,13294402 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,12714944 0,13476721 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,12714944 0,13470786 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,12714944 0,13464857 ! activation of MAPK activity GO:0000187 115 67 0,000 0,12714944 0,13458933 ! chromosome segregation GO:0007059 113 67 0,000 0,12714944 0,13453015 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,12714944 0,13447101 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,12714944 0,13441193 ! hexose catabolic process GO:0019320 104 67 0,000 0,12714944 0,1343529 ! activation of immune response GO:0002253 105 67 0,000 0,12714944 0,13429392 ! amino acid transport GO:0006865 125 68 0,000 0,12892128 0,13610558 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,12892128 0,13604588 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,12892128 0,13598624 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,12892128 0,13592665 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,12892128 0,13586711 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,12892128 0,13580762 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,13068959 0,13761013 ! negative regulation of cell size GO:0045792 134 69 0,000 0,13068959 0,13754994 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,13068959 0,13748979 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,13068959 0,1374297 ! urogenital system development GO:0001655 137 69 0,000 0,13068959 0,13736966 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,13068959 0,13730967 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,13068959 0,13724974 ! amine catabolic process GO:0009310 117 71 0,000 0,13421561 0,14089126 ! humoral immune response GO:0006959 109 71 0,000 0,13421561 0,14082982 ! B cell activation GO:0042113 160 71 0,000 0,13421561 0,14076843 ! acute inflammatory response GO:0002526 113 72 0,000 0,13597335 0,14254984 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,13597335 0,14248775 ! carbohydrate transport GO:0008643 110 72 0,000 0,13597335 0,14242572 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,13597335 0,14236374 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,13597335 0,14230182 ! learning or memory GO:0007611 147 73 0,000 0,13772757 0,14407501 ! regulation of blood pressure GO:0008217 125 73 0,000 0,13772757 0,1440124 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,13772757 0,14394984 ! axon guidance GO:0007411 139 73 0,000 0,13772757 0,14388734 ! fertilization GO:0009566 90 73 0,000 0,13772757 0,14382488 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,13947829 0,14558992 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,13947829 0,14552678 ! neurotransmitter transport GO:0006836 123 74 0,000 0,13947829 0,1454637 ! meiosis GO:0007126 121 74 0,000 0,13947829 0,14540068 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,13947829 0,14533771 ! eye development GO:0001654 143 74 0,000 0,13947829 0,14527479 ! organelle localization GO:0051640 136 74 0,000 0,13947829 0,14521193 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,14122551 0,14696738 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,14122551 0,14690384 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,14122551 0,14684036 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,14122551 0,14677693 ! meiotic cell cycle GO:0051321 122 75 0,000 0,14122551 0,14671355 ! rhythmic process GO:0048511 128 75 0,000 0,14122551 0,14665023 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,14122551 0,14658696 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,14296925 0,1483329 ! defense response to bacterium GO:0042742 89 76 0,000 0,14296925 0,14826897 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,14296925 0,14820509 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,14296925 0,14814126 ! regulation of catabolic process GO:0009894 161 76 0,000 0,14296925 0,14807749 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,1447095 0,14981543 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,1447095 0,14975099 ! blood coagulation GO:0007596 146 78 0,000 0,14644627 0,15148312 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,14644627 0,15141802 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,14644627 0,15135298 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,14644627 0,15128799 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,14817958 0,1530129 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,14817958 0,15294726 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,14817958 0,15288167 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,14817958 0,15281614 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,14817958 0,15275067 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,14990942 0,1544677 ! response to metal ion GO:0010038 140 80 0,000 0,14990942 0,15440157 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,14990942 0,1543355 ! inorganic anion transport GO:0015698 138 80 0,000 0,14990942 0,15426949 ! digestion GO:0007586 112 81 0,000 0,15163581 0,15597938 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,15163581 0,15591272 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,15163581 0,15584612 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,15163581 0,15577957 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,15335875 0,15748235 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,15335875 0,15741517 ! response to drug GO:0042493 143 82 0,000 0,15335875 0,15734804 ! response to nutrient GO:0007584 125 82 0,000 0,15335875 0,15728097 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,15335875 0,15721395 ! regulation of lyase activity GO:0051339 160 83 0,000 0,15507825 0,15890897 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,15679431 0,16059903 ! hemostasis GO:0007599 158 84 0,000 0,15679431 0,16053069 ! negative regulation of growth GO:0045926 155 84 0,000 0,15679431 0,1604624 ! regulation of ligase activity GO:0051340 142 84 0,000 0,15679431 0,16039418 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,15679431 0,16032601 ! response to unfolded protein GO:0006986 131 85 0,000 0,15850694 0,16200837 ! nucleosome assembly GO:0006334 122 85 0,000 0,15850694 0,16193958 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,15850694 0,16187084 ! amine biosynthetic process GO:0009309 138 86 0,000 0,16021616 0,16354691 ! response to inorganic substance GO:0010035 153 86 0,000 0,16021616 0,16347755 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,16021616 0,16340826 ! chromatin assembly GO:0031497 124 86 0,000 0,16021616 0,16333901 ! tube morphogenesis GO:0035239 176 86 0,000 0,16021616 0,16326983 ! mitochondrion organization GO:0007005 148 86 0,000 0,16021616 0,16320071 ! alcohol catabolic process GO:0046164 130 86 0,000 0,16021616 0,16313164 ! amine transport GO:0015837 155 86 0,000 0,16021616 0,16306264 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,16192196 0,16472906 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,16192196 0,16465944 ! cellular respiration GO:0045333 135 88 0,000 0,16362434 0,16632031 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,16362434 0,16625007 ! regulation of DNA binding GO:0051101 155 88 0,000 0,16362434 0,1661799 ! regulation of neurological system process GO:0031644 148 88 0,000 0,16362434 0,16610978 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,16362434 0,16603972 ! cellular defense response GO:0006968 114 89 0,000 0,16532333 0,16769306 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,16532333 0,16762239 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,16701893 0,16927023 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,16701893 0,16919896 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,16701893 0,16912775 ! sterol metabolic process GO:0016125 152 91 0,000 0,16871113 0,17076945 ! response to protein stimulus GO:0051789 149 91 0,000 0,16871113 0,17069764 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,16871113 0,17062589 ! regulation of defense response GO:0031347 149 92 0,000 0,17039996 0,17226147 ! nucleosome organization GO:0034728 138 92 0,000 0,17039996 0,17218912 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,17039996 0,17211683 ! vitamin metabolic process GO:0006766 139 92 0,000 0,17039996 0,1720446 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,1720854 0,17367344 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,1720854 0,17360062 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,1720854 0,17352786 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,17376748 0,17515064 ! female pregnancy GO:0007565 164 94 0,000 0,17376748 0,17507729 ! transcription initiation GO:0006352 153 94 0,000 0,17376748 0,17500401 ! forebrain development GO:0030900 188 95 0,000 0,1754462 0,17662074 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,1754462 0,17654687 ! leukocyte differentiation GO:0002521 202 96 0,000 0,17712157 0,17815823 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,17712157 0,17808378 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,17712157 0,1780094 ! positive regulation of immune response GO:0050778 156 96 0,000 0,17712157 0,17793507 ! detection of stimulus GO:0051606 151 96 0,000 0,17712157 0,17786081 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,17879358 0,1794649 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,17879358 0,17939006 ! protein ubiquitination GO:0016567 217 97 0,000 0,17879358 0,17931528 ! hormone metabolic process GO:0042445 157 97 0,000 0,17879358 0,17924057 ! response to virus GO:0009615 160 98 0,000 0,18046226 0,18083806 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,18046226 0,18076278 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,18046226 0,18068755 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,1821276 0,18227912 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,1821276 0,18220333 ! cell cycle arrest GO:0007050 213 100 0,000 0,18378961 0,18378961