pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/611-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 5,704E-07 1,312E-03 ! androgen receptor signaling pathway GO:0030521 54 33 3,000 8,258E-07 9,497E-04 ! auditory receptor cell differentiation GO:0042491 25 12 2,000 2,227E-06 1,707E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 3,000 2,451E-06 1,409E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 4,9E-06 2,254E-03 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 5,634E-06 2,16E-03 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 2,000 6,831E-06 2,244E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 7,671E-06 2,205E-03 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 8,184E-06 2,092E-03 ! negative regulation of kinase activity GO:0033673 100 58 3,000 8,226E-06 1,892E-03 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 8,226E-06 1,72E-03 ! negative regulation of transferase activity GO:0051348 105 61 3,000 1,007E-05 1,93E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 1,14E-05 2,017E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 1,146E-05 1,882E-03 ! cell cycle arrest GO:0007050 150 86 3,000 3,937E-05 6,037E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 3,937E-05 5,659E-03 ! interphase GO:0051325 159 88 3,000 4,309E-05 5,83E-03 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 4,829E-05 6,17E-03 ! positive regulation of microtubule polymerization GO:0031116 9 5 1,000 4,829E-05 5,846E-03 ! protein homooligomerization GO:0051260 52 35 2,000 6,394E-05 7,353E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 1,000 7,233E-05 7,922E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of insulin secretion GO:0032024 8 6 1,000 7,233E-05 7,562E-03 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 7,233E-05 7,233E-03 ! gas homeostasis GO:0033483 11 6 1,000 7,233E-05 6,932E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 1,000 7,233E-05 6,655E-03 ! regulation of microtubule polymerization GO:0031113 11 6 1,000 7,233E-05 6,399E-03 ! inner ear development GO:0048839 57 40 2,000 9,578E-05 8,159E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,011E-04 8,306E-03 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,011E-04 8,02E-03 ! negative regulation of JAK-STAT cascade GO:0046426 15 7 1,000 1,011E-04 7,753E-03 ! vesicle fusion GO:0006906 15 7 1,000 1,011E-04 7,503E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,346E-04 9,677E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,346E-04 9,384E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,346E-04 9,108E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,346E-04 8,848E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,346E-04 8,602E-03 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,346E-04 8,369E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 1,365E-04 8,263E-03 ! response to UV GO:0009411 75 46 2,000 1,458E-04 8,599E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 2,000 1,555E-04 8,942E-03 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 1,729E-04 9,697E-03 ! positive regulation of peptide secretion GO:0002793 15 9 1,000 1,729E-04 9,466E-03 ! regulation of hormone metabolic process GO:0032350 15 9 1,000 1,729E-04 9,246E-03 ! positive regulation of protein polymerization GO:0032273 15 9 1,000 1,729E-04 9,036E-03 ! localization within membrane GO:0051668 15 9 1,000 1,729E-04 8,835E-03 ! RNA elongation GO:0006354 62 49 2,000 1,762E-04 8,808E-03 ! ear development GO:0043583 72 50 2,000 1,871E-04 9,156E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 2,158E-04 0,01033918 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 2,158E-04 0,01012817 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 2,158E-04 9,926E-03 ! regulation of lipid metabolic process GO:0019216 84 56 2,000 2,622E-04 0,01182423 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,634E-04 0,01164827 ! stem cell development GO:0048864 29 11 1,000 2,634E-04 0,01142849 GO:0019827|stem cell maintenance, ! lung development GO:0030324 94 59 2,000 3,061E-04 0,01303623 ! gland morphogenesis GO:0022612 23 12 1,000 3,156E-04 0,01319687 ! negative regulation of cell growth GO:0030308 106 62 2,000 3,544E-04 0,01455688 ! respiratory tube development GO:0030323 99 62 2,000 3,544E-04 0,0143015 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 3,724E-04 0,01476875 ! positive regulation of protein complex assembly GO:0031334 19 13 1,000 3,724E-04 0,01451843 ! lipid localization GO:0010876 24 13 1,000 3,724E-04 0,01427646 GO:0019915|lipid storage, ! organelle fusion GO:0048284 28 13 1,000 3,724E-04 0,01404242 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 3,724E-04 0,01381593 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 3,724E-04 0,01359663 ! negative regulation of cell size GO:0045792 108 64 2,000 3,893E-04 0,01398871 ! respiratory system development GO:0060541 100 64 2,000 3,893E-04 0,0137735 ! protein oligomerization GO:0051259 100 65 2,000 4,075E-04 0,01419929 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 4,339E-04 0,01489468 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 1,000 4,339E-04 0,01467564 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 4,339E-04 0,01446295 ! intracellular protein transmembrane transport GO:0065002 102 68 2,000 4,653E-04 0,01528972 ! lipid phosphorylation GO:0046834 23 15 1,000 4,999E-04 0,01619509 ! myoblast differentiation GO:0045445 27 15 1,000 4,999E-04 0,01597016 ! regulation of vasodilation GO:0042312 24 15 1,000 4,999E-04 0,01575139 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 2,000 5,067E-04 0,01574914 ! muscle cell differentiation GO:0042692 104 71 2,000 5,283E-04 0,01619973 ! regulation of peptidase activity GO:0052547 106 72 2,000 5,504E-04 0,01665598 ! G1 phase GO:0051318 27 16 1,000 5,705E-04 0,0170424 ! negative regulation of growth GO:0045926 123 75 2,000 6,203E-04 0,01828986 ! positive regulation of hormone secretion GO:0046887 24 17 1,000 6,457E-04 0,01879922 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 6,457E-04 0,01856423 ! inactivation of MAPK activity GO:0000188 27 17 1,000 6,457E-04 0,01833504 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 6,457E-04 0,01811145 ! stem cell differentiation GO:0048863 36 17 1,000 6,457E-04 0,01789324 ! pancreas development GO:0031016 26 18 1,000 7,254E-04 0,01986224 ! positive regulation of cytoskeleton organization GO:0051495 33 18 1,000 7,254E-04 0,01962856 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 8,096E-04 0,02165218 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 1,000 8,096E-04 0,02140331 ! regulation of fatty acid metabolic process GO:0019217 28 19 1,000 8,096E-04 0,02116009 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 8,096E-04 0,02092234 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 8,096E-04 0,02068987 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 8,096E-04 0,0204625 ! Golgi vesicle transport GO:0048193 138 85 2,000 8,934E-04 0,02233544 ! transcription initiation GO:0006352 118 85 2,000 8,934E-04 0,02209527 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 8,983E-04 0,02197951 ! positive regulation of B cell activation GO:0050871 31 20 1,000 8,983E-04 0,02174814 ! skeletal muscle tissue development GO:0007519 123 87 2,000 9,558E-04 0,02289999 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 9,558E-04 0,02266391 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 9,915E-04 0,02326878 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 1,000 9,915E-04 0,02303374 ! vesicle docking GO:0048278 27 21 1,000 9,915E-04 0,0228034 ! regulation of insulin secretion GO:0050796 26 21 1,000 9,915E-04 0,02257763 ! regulation of vasoconstriction GO:0019229 31 21 1,000 9,915E-04 0,02235628 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 9,915E-04 0,02213923 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 9,915E-04 0,02192635 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 1,089E-03 0,02385566 ! vasculogenesis GO:0001570 33 22 1,000 1,089E-03 0,0236306 ! regulation of smooth muscle contraction GO:0006940 36 22 1,000 1,089E-03 0,02340976 ! membrane depolarization GO:0051899 35 22 1,000 1,089E-03 0,023193 ! regulation of blood coagulation GO:0030193 34 22 1,000 1,089E-03 0,02298022 ! cell fate commitment GO:0045165 141 92 2,000 1,124E-03 0,02349683 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 1,191E-03 0,02468054 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 1,191E-03 0,02446017 ! cell fate determination GO:0001709 45 23 1,000 1,191E-03 0,02424371 ! response to light stimulus GO:0009416 153 96 2,000 1,271E-03 0,02563759 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 1,298E-03 0,02595116 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 1,298E-03 0,02572744 ! fat cell differentiation GO:0045444 37 24 1,000 1,298E-03 0,02550755 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 1,298E-03 0,02529138 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 1,408E-03 0,02722127 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 1,000 1,408E-03 0,02699442 ! regulation of peptide secretion GO:0002791 34 25 1,000 1,408E-03 0,02677133 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 1,524E-03 0,02872408 ! post-embryonic development GO:0009791 42 26 1,000 1,524E-03 0,02849055 ! negative regulation of protein kinase cascade GO:0010741 51 26 1,000 1,524E-03 0,02826079 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 1,524E-03 0,02803471 ! regulation of coagulation GO:0050818 39 26 1,000 1,524E-03 0,02781221 ! membrane docking GO:0022406 39 27 1,000 1,643E-03 0,02975875 ! cholesterol homeostasis GO:0042632 46 28 1,000 1,767E-03 0,0317528 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 34 28 1,000 1,767E-03 0,03150665 ! erythrocyte differentiation GO:0030218 38 28 1,000 1,767E-03 0,03126429 ! mesoderm formation GO:0001707 46 28 1,000 1,767E-03 0,03102563 ! negative regulation of MAP kinase activity GO:0043407 54 28 1,000 1,767E-03 0,03079059 ! regulation of B cell activation GO:0050864 42 28 1,000 1,767E-03 0,03055908 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 1,895E-03 0,03253196 ! formation of primary germ layer GO:0001704 48 29 1,000 1,895E-03 0,03229098 ! cholesterol transport GO:0030301 46 30 1,000 2,028E-03 0,0342948 GO:0015918|sterol transport, ! regulation of microtubule-based process GO:0032886 58 30 1,000 2,028E-03 0,03404448 ! mammary gland development GO:0030879 57 31 1,000 2,165E-03 0,03607787 ! mesoderm morphogenesis GO:0048332 49 31 1,000 2,165E-03 0,03581831 ! neutral lipid metabolic process GO:0006638 41 32 1,000 2,306E-03 0,03787998 GO:0006639|acylglycerol metabolic process, ! calcium-mediated signaling GO:0019722 50 32 1,000 2,306E-03 0,03761133 ! carbohydrate homeostasis GO:0033500 39 33 1,000 2,451E-03 0,03970004 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 55 33 1,000 2,451E-03 0,03942241 ! glycerol ether metabolic process GO:0006662 44 34 1,000 2,601E-03 0,04153699 ! erythrocyte homeostasis GO:0034101 45 34 1,000 2,601E-03 0,04125052 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 2,601E-03 0,04096799 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 2,601E-03 0,04068929 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 2,754E-03 0,04280349 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 2,754E-03 0,04251622 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of hormone secretion GO:0046883 48 36 1,000 2,912E-03 0,04465424 ! organic ether metabolic process GO:0018904 46 36 1,000 2,912E-03 0,04435852 ! tissue remodeling GO:0048771 62 36 1,000 2,912E-03 0,04406669 ! striated muscle cell differentiation GO:0051146 54 38 1,000 3,241E-03 0,0487143 ! mesenchymal cell development GO:0014031 64 38 1,000 3,241E-03 0,04839798 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 3,411E-03 0,05061378 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 3,585E-03 0,05286182 ! epidermal cell differentiation GO:0009913 53 40 1,000 3,585E-03 0,05252512 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 3,585E-03 0,05219268 ! positive regulation of protein transport GO:0051222 55 40 1,000 3,585E-03 0,05186442 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 3,947E-03 0,05673291 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 3,947E-03 0,05638053 ! vesicle organization GO:0016050 79 43 1,000 4,133E-03 0,05868332 ! response to insulin stimulus GO:0032868 63 43 1,000 4,133E-03 0,0583233 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 4,324E-03 0,06064282 ! positive regulation of cell cycle GO:0045787 77 45 1,000 4,519E-03 0,06299028 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 4,92E-03 0,06817428 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of protein polymerization GO:0032271 71 47 1,000 4,92E-03 0,06776605 ! regulation of muscle contraction GO:0006937 69 48 1,000 5,127E-03 0,07019291 ! gastrulation GO:0007369 73 48 1,000 5,127E-03 0,06977757 ! regulation of intracellular transport GO:0032386 78 49 1,000 5,338E-03 0,07221749 ! skeletal muscle fiber development GO:0048741 73 50 1,000 5,552E-03 0,07468177 ! membrane fusion GO:0006944 80 50 1,000 5,552E-03 0,07424757 ! lipid modification GO:0030258 73 50 1,000 5,552E-03 0,07381839 ! positive regulation of secretion GO:0051047 71 51 1,000 5,771E-03 0,07628274 ! activation of phospholipase C activity GO:0007202 87 51 1,000 5,771E-03 0,07584683 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 5,771E-03 0,07541589 ! positive regulation of cell migration GO:0030335 92 51 1,000 5,771E-03 0,07498981 ! positive regulation of organelle organization GO:0010638 82 51 1,000 5,771E-03 0,07456852 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 5,993E-03 0,07700991 ! nucleotide-excision repair GO:0006289 64 52 1,000 5,993E-03 0,07658208 ! regulation of protein complex assembly GO:0043254 81 54 1,000 6,45E-03 0,08195945 ! regulation of phospholipase activity GO:0010517 90 54 1,000 6,45E-03 0,08150912 ! DNA catabolic process GO:0006308 67 54 1,000 6,45E-03 0,08106372 ! positive regulation of lipase activity GO:0060193 90 54 1,000 6,45E-03 0,08062315 ! mesoderm development GO:0007498 76 55 1,000 6,684E-03 0,0830967 ! positive regulation of cell motion GO:0051272 99 56 1,000 6,922E-03 0,08559097 ! camera-type eye development GO:0043010 88 57 1,000 7,163E-03 0,08810543 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 7,163E-03 0,08763678 ! myeloid cell differentiation GO:0030099 85 59 1,000 7,658E-03 0,09319279 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 7,911E-03 0,09576465 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 7,911E-03 0,09526327 GO:0035113|embryonic appendage morphogenesis, ! homeostasis of number of cells GO:0048872 84 61 1,000 8,168E-03 0,09784238 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 8,692E-03 0,10358705 ! regulation of lipase activity GO:0060191 109 63 1,000 8,692E-03 0,10305309 ! cell cycle checkpoint GO:0000075 108 64 1,000 8,96E-03 0,10568376 ! appendage morphogenesis GO:0035107 93 64 1,000 8,96E-03 0,10514456 GO:0035108|limb morphogenesis, ! regulation of caspase activity GO:0043281 97 65 1,000 9,232E-03 0,10778079 ! appendage development GO:0048736 94 65 1,000 9,232E-03 0,10723644 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 9,232E-03 0,10669756 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 9,786E-03 0,11253485 ! eye development GO:0001654 111 70 1,000 0,01064374 0,12179406 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,01064374 0,12119112 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01110594 0,12583083 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01110594 0,12521401 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01110594 0,12460321 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01110594 0,12399834 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01110594 0,12339932 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01110594 0,12280605 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01110594 0,12221846 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01110594 0,12163647 ! sleep GO:0030431 11 5 0,000 0,01110594 0,12105999 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01110594 0,12048895 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01110594 0,11992328 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01110594 0,11936289 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01110594 0,11880771 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01110594 0,11825768 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01110594 0,11771271 ! tongue development GO:0043586 6 5 0,000 0,01110594 0,11717274 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01110594 0,11663771 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01110594 0,11610754 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01110594 0,11558216 ! cobalt ion transport GO:0006824 9 5 0,000 0,01110594 0,11506152 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01110594 0,11454555 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01110594 0,11403419 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01110594 0,11352737 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01110594 0,11302504 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01110594 0,11252713 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01110594 0,11203359 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01110594 0,11154436 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01110594 0,11105938 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01110594 0,11057861 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01110594 0,11010198 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01110594 0,10962943 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01110594 0,10916093 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01110594 0,10869642 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01110594 0,10823584 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01110594 0,10777915 ! malate metabolic process GO:0006108 7 5 0,000 0,01110594 0,1073263 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01110594 0,10687723 ! behavioral response to pain GO:0048266 7 5 0,000 0,01110594 0,10643191 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01110594 0,10599028 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01110594 0,10555231 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01110594 0,10511794 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01110594 0,10468712 ! mating behavior GO:0007617 6 5 0,000 0,01110594 0,10425983 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01110594 0,10383601 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01110594 0,10341562 ! rhythmic behavior GO:0007622 12 5 0,000 0,01110594 0,10299862 ! copulation GO:0007620 7 5 0,000 0,01110594 0,10258497 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01110594 0,10217463 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01110594 0,10176756 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01110594 0,10136372 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01110594 0,10096308 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01110594 0,10056558 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01110594 0,10017121 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01110594 0,09977992 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01110594 0,09939167 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01110594 0,09900643 ! response to protozoan GO:0001562 9 5 0,000 0,01110594 0,09862416 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,01110594 0,09824484 ! lymph vessel development GO:0001945 7 5 0,000 0,01110594 0,09786842 ! endochondral ossification GO:0001958 12 5 0,000 0,01110594 0,09749488 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01110594 0,09712418 ! parathyroid gland development GO:0060017 8 5 0,000 0,01110594 0,09675628 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01110594 0,09639116 ! anagen GO:0042640 6 5 0,000 0,01110594 0,09602879 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01110594 0,09566913 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01110594 0,09531216 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01110594 0,09495784 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01110594 0,09460614 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01110594 0,09425704 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01110594 0,09391051 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01110594 0,09356651 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01110594 0,09322503 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01110594 0,09288603 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01110594 0,09254949 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01110594 0,09221537 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01110594 0,09188366 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01110594 0,09155433 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01110594 0,09122735 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01110594 0,0909027 ! ovulation GO:0030728 6 5 0,000 0,01110594 0,09058035 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01110594 0,09026028 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01110594 0,08994246 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01110594 0,08962687 ! response to pH GO:0009268 9 5 0,000 0,01110594 0,08931349 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01110594 0,08900229 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01110594 0,08869326 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01110594 0,08838636 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01110594 0,08808158 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01110594 0,08777889 ! polyol catabolic process GO:0046174 7 5 0,000 0,01110594 0,08747828 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01110594 0,08717972 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01110594 0,08688319 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01110594 0,08658867 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01110594 0,08629614 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01110594 0,08600558 ! urea metabolic process GO:0019627 6 5 0,000 0,01110594 0,08571697 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01110594 0,0854303 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01110594 0,08514553 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01110594 0,08486265 ! neutrophil activation GO:0042119 5 5 0,000 0,01110594 0,08458165 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01110594 0,0843025 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01110594 0,08402519 ! response to food GO:0032094 5 5 0,000 0,01110594 0,0837497 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01110594 0,08347601 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01110594 0,0832041 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01110594 0,08293396 ! forebrain neuron development GO:0021884 7 5 0,000 0,01110594 0,08266556 ! melanosome organization GO:0032438 7 5 0,000 0,01110594 0,0823989 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01110594 0,08213395 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01110594 0,0818707 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01110594 0,08160913 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01110594 0,08134923 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01110594 0,08109098 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01110594 0,08083436 ! nucleoside transport GO:0015858 6 5 0,000 0,01110594 0,08057936 ! nucleoside salvage GO:0043174 7 5 0,000 0,01110594 0,08032597 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01110594 0,08007416 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01110594 0,07982393 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01110594 0,07957526 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01110594 0,07932813 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01110594 0,07908253 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01110594 0,07883845 ! depyrimidination GO:0045008 8 5 0,000 0,01110594 0,07859587 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01110594 0,07835478 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01110594 0,07811516 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01110594 0,07787701 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01110594 0,0776403 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01110594 0,07740503 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01110594 0,07717117 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01110594 0,07693873 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01110594 0,07670768 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01110594 0,07647802 ! monocyte differentiation GO:0030224 8 5 0,000 0,01110594 0,07624973 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01110594 0,07602279 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01110594 0,07579721 ! centrosome duplication GO:0051298 5 5 0,000 0,01110594 0,07557295 ! response to UV-C GO:0010225 6 5 0,000 0,01110594 0,07535002 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01110594 0,07512841 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01110594 0,07490809 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01110594 0,07468906 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01110594 0,07447131 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01110594 0,07425482 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01110594 0,07403959 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01110594 0,0738256 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01110594 0,07361285 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01110594 0,07340132 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01110594 0,073191 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01110594 0,07298188 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01110594 0,07277396 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01110594 0,07256721 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01110594 0,07236164 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01110594 0,07215723 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01110594 0,07195397 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01110594 0,07175185 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01110594 0,07155086 ! neural tube patterning GO:0021532 6 5 0,000 0,01110594 0,071351 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01110594 0,07115225 ! histone demethylation GO:0016577 9 5 0,000 0,01110594 0,07095461 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01110594 0,07075806 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01110594 0,07056259 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01110594 0,0703682 ! enteric nervous system development GO:0048484 8 5 0,000 0,01110594 0,07017489 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01110594 0,06998263 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01110594 0,06979142 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01110594 0,06960125 ! transcription termination GO:0006353 8 5 0,000 0,01110594 0,06941211 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01110594 0,06922401 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01110594 0,06903691 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01110594 0,06885083 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,01110594 0,06866575 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01110594 0,06848166 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01110594 0,06829855 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01110594 0,06811642 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01110594 0,06793526 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01110594 0,06775506 ! apical protein localization GO:0045176 6 5 0,000 0,01110594 0,06757582 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01110594 0,06739752 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01110594 0,06722015 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01110594 0,06704372 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01110594 0,06686822 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01110594 0,06669362 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01110594 0,06651994 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01110594 0,06634716 ! glial cell migration GO:0008347 10 5 0,000 0,01110594 0,06617528 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01110594 0,06600429 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01110594 0,06583417 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01110594 0,06566493 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01110594 0,06549656 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01110594 0,06532905 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01110594 0,06516239 ! neural plate development GO:0001840 6 5 0,000 0,01110594 0,06499659 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01110594 0,06483162 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01110594 0,06466749 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01110594 0,06450419 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01110594 0,06434171 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01110594 0,06418005 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01110594 0,06401919 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01110594 0,06385915 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01110594 0,0636999 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01110594 0,06354144 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01110594 0,06338377 ! spindle assembly GO:0051225 5 5 0,000 0,01110594 0,06322688 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01110594 0,06307076 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01110594 0,06291541 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01110594 0,06276083 ! organ regeneration GO:0031100 7 5 0,000 0,01110594 0,06260701 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01110594 0,06245393 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01110594 0,06230161 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01110594 0,06215002 GO:0055081|anion homeostasis, ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,0112337 0,06271242 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,0112337 0,06256058 ! response to oxygen levels GO:0070482 137 74 1,000 0,01183783 0,0657657 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,01183783 0,06560723 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,01183783 0,06544952 ! regulation of protein transport GO:0051223 114 76 1,000 0,01245598 0,06870204 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 1,000 0,01277027 0,07026706 ! tRNA transcription GO:0009304 11 6 0,000 0,01331266 0,07307665 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01331266 0,07290266 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01331266 0,07272949 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01331266 0,07255715 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01331266 0,07238562 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01331266 0,0722149 ! regulation of helicase activity GO:0051095 11 6 0,000 0,01331266 0,07204498 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01331266 0,07187586 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01331266 0,07170753 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01331266 0,07153999 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01331266 0,07137323 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01331266 0,07120725 ! prostate gland development GO:0030850 9 6 0,000 0,01331266 0,07104204 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01331266 0,07087759 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01331266 0,0707139 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01331266 0,07055096 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01331266 0,07038878 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01331266 0,07022733 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01331266 0,07006663 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01331266 0,06990666 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01331266 0,06974742 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01331266 0,0695889 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01331266 0,06943111 ! neuron adhesion GO:0007158 9 6 0,000 0,01331266 0,06927402 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,01331266 0,06911765 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01331266 0,06896198 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01331266 0,06880701 ! signal peptide processing GO:0006465 8 6 0,000 0,01331266 0,06865273 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01331266 0,06849914 ! mRNA stabilization GO:0048255 15 6 0,000 0,01331266 0,06834624 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01331266 0,06819403 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01331266 0,06804248 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01331266 0,06789161 ! opsonization GO:0008228 8 6 0,000 0,01331266 0,06774141 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01331266 0,06759187 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01331266 0,06744299 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01331266 0,06729476 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01331266 0,06714719 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01331266 0,06700026 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01331266 0,06685397 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01331266 0,06670832 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,01331266 0,0665633 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01331266 0,06641891 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01331266 0,06627515 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01331266 0,066132 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01331266 0,06598948 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01331266 0,06584756 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01331266 0,06570626 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01331266 0,06556556 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01331266 0,06542546 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01331266 0,06528596 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01331266 0,06514706 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,01331266 0,06500874 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01331266 0,06487101 ! thymic T cell selection GO:0045061 12 6 0,000 0,01331266 0,06473386 ! protein lipoylation GO:0009249 10 6 0,000 0,01331266 0,06459729 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01331266 0,0644613 ! pigment granule organization GO:0048753 11 6 0,000 0,01331266 0,06432588 ! drug transport GO:0015893 6 6 0,000 0,01331266 0,06419102 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01331266 0,06405673 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,01331266 0,063923 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01331266 0,06378983 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01331266 0,06365721 ! histidine metabolic process GO:0006547 6 6 0,000 0,01331266 0,06352514 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01331266 0,06339362 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01331266 0,06326264 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! glycine catabolic process GO:0006546 9 6 0,000 0,01331266 0,0631322 ! adenohypophysis development GO:0021984 10 6 0,000 0,01331266 0,0630023 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01331266 0,06287293 ! hyperosmotic response GO:0006972 8 6 0,000 0,01331266 0,06274409 ! microtubule nucleation GO:0007020 10 6 0,000 0,01331266 0,06261578 ! ER overload response GO:0006983 7 6 0,000 0,01331266 0,06248799 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01331266 0,06236073 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01331266 0,06223398 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01331266 0,06210774 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01331266 0,06198202 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01331266 0,0618568 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01331266 0,06173209 ! response to dietary excess GO:0002021 7 6 0,000 0,01331266 0,06160788 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01331266 0,06148417 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01331266 0,06136096 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01331266 0,06123823 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01331266 0,061116 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01331266 0,06099426 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01331266 0,060873 ! neuron apoptosis GO:0051402 8 6 0,000 0,01331266 0,06075222 ! organic alcohol transport GO:0015850 9 6 0,000 0,01331266 0,06063192 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01331266 0,06051209 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01331266 0,06039274 ! male sex determination GO:0030238 9 6 0,000 0,01331266 0,06027385 ! carnitine transport GO:0015879 8 6 0,000 0,01331266 0,06015544 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01331266 0,06003748 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01331266 0,05991999 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01331266 0,05980296 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01331266 0,05968639 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01331266 0,05957027 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01331266 0,0594546 ! parturition GO:0007567 12 6 0,000 0,01331266 0,05933937 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01331266 0,0592246 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01331266 0,05911027 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01331266 0,05899637 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01331266 0,05888292 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01331266 0,0587699 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01331266 0,05865731 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01331266 0,05854516 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01331266 0,05843343 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01331266 0,05832213 ! macrophage differentiation GO:0030225 10 6 0,000 0,01331266 0,05821125 ! astrocyte development GO:0014002 14 6 0,000 0,01331266 0,05810079 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01331266 0,05799075 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01331266 0,05788113 ! interaction with symbiont GO:0051702 8 6 0,000 0,01331266 0,05777192 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01331266 0,05766312 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01331266 0,05755473 ! eating behavior GO:0042755 6 6 0,000 0,01331266 0,05744675 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01331266 0,05733917 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01331266 0,057232 ! response to copper ion GO:0046688 9 6 0,000 0,01331266 0,05712522 ! DNA topological change GO:0006265 8 6 0,000 0,01331266 0,05701884 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01331266 0,05691286 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01331266 0,05680727 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01331266 0,05670207 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01331266 0,05659726 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01331266 0,05649284 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01331266 0,0563888 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01331266 0,05628514 ! hair follicle maturation GO:0048820 7 6 0,000 0,01331266 0,05618187 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01331266 0,05607897 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01331266 0,05597645 ! Schwann cell development GO:0014044 14 6 0,000 0,01331266 0,0558743 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01331266 0,05577253 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01331266 0,05567112 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01331266 0,05557009 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01331266 0,05546942 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01331266 0,05536911 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01331266 0,05526916 ! histone ubiquitination GO:0016574 7 6 0,000 0,01331266 0,05516958 ! regulation of meiosis GO:0040020 10 6 0,000 0,01331266 0,05507035 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01331266 0,05497149 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01331266 0,05487297 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01331266 0,05477481 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01331266 0,054677 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01331266 0,05457953 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01331266 0,05448242 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01331266 0,05438564 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01331266 0,05428922 ! receptor internalization GO:0031623 9 6 0,000 0,01331266 0,05419313 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01331266 0,05409738 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01331266 0,05400197 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01331266 0,0539069 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01331266 0,05381216 ! protein deubiquitination GO:0016579 8 6 0,000 0,01331266 0,05371775 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01331266 0,05362367 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,01331266 0,05352993 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01331266 0,0534365 ! axonal fasciculation GO:0007413 9 6 0,000 0,01331266 0,05334341 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01331266 0,05325064 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01331266 0,05315819 ! midbrain development GO:0030901 6 6 0,000 0,01331266 0,05306606 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01331266 0,05297425 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01331266 0,05288276 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01331266 0,05279158 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01331266 0,05270072 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01331266 0,05261017 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01331266 0,05251993 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01331266 0,05243 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01331266 0,05234037 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01331266 0,05225105 ! adult feeding behavior GO:0008343 6 6 0,000 0,01331266 0,05216204 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01331266 0,05207333 ! blastocyst growth GO:0001832 15 6 0,000 0,01331266 0,05198492 ! pigment granule transport GO:0051904 12 6 0,000 0,01331266 0,05189681 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01331266 0,051809 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01331266 0,05172148 ! catecholamine transport GO:0051937 7 6 0,000 0,01331266 0,05163426 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01331266 0,05154734 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01331266 0,0514607 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01331266 0,05137436 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01331266 0,0512883 ! protein prenylation GO:0018342 10 6 0,000 0,01331266 0,05120254 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01331266 0,05111706 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01331266 0,05103186 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01331266 0,05094695 ! forebrain development GO:0030900 131 80 1,000 0,01373385 0,05247152 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,01406188 0,05363571 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,01439331 0,05480897 GO:0060348|bone development, ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,0154078 0,05857511 ! regulation of protein localization GO:0032880 132 85 1,000 0,0154078 0,05847845 ! regulation of membrane potential GO:0042391 128 85 1,000 0,0154078 0,05838211 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,0154078 0,05828609 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,01551458 0,05859366 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,01551458 0,05849761 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,01551458 0,05840187 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,01551458 0,05830644 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,01551458 0,05821132 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01551458 0,05811652 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,01551458 0,05802202 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01551458 0,05792783 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,01551458 0,05783394 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,01551458 0,05774036 ! reproductive behavior GO:0019098 12 7 0,000 0,01551458 0,05764708 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,01551458 0,0575541 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,01551458 0,05746142 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,01551458 0,05736904 ! oligopeptide transport GO:0006857 11 7 0,000 0,01551458 0,05727695 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,01551458 0,05718516 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,01551458 0,05709366 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! RNA methylation GO:0001510 11 7 0,000 0,01551458 0,05700246 ! pericardium development GO:0060039 8 7 0,000 0,01551458 0,05691155 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,01551458 0,05682092 ! fibril organization GO:0043206 13 7 0,000 0,01551458 0,05673059 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,01551458 0,05664054 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01551458 0,05655078 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,01551458 0,0564613 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,01551458 0,0563721 ! lipoprotein transport GO:0042953 9 7 0,000 0,01551458 0,05628319 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,01551458 0,05619455 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01551458 0,0561062 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01551458 0,05601812 ! estrogen metabolic process GO:0008210 14 7 0,000 0,01551458 0,05593031 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,01551458 0,05584279 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,01551458 0,05575553 ! chemosensory behavior GO:0007635 9 7 0,000 0,01551458 0,05566855 ! microtubule bundle formation GO:0001578 8 7 0,000 0,01551458 0,05558184 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,01551458 0,0554954 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,01551458 0,05540922 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,01551458 0,05532332 ! leukocyte degranulation GO:0043299 10 7 0,000 0,01551458 0,05523768 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,01551458 0,0551523 ! reflex GO:0060004 12 7 0,000 0,01551458 0,05506719 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01551458 0,05498234 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,01551458 0,05489775 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01551458 0,05481343 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,01551458 0,05472936 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,01551458 0,05464554 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01551458 0,05456199 ! spinal cord patterning GO:0021511 7 7 0,000 0,01551458 0,05447869 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,01551458 0,05439564 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,01551458 0,05431285 ! adrenal gland development GO:0030325 17 7 0,000 0,01551458 0,0542303 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,01551458 0,05414801 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,01551458 0,05406597 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,01551458 0,05398418 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,01551458 0,05390263 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,01551458 0,05382133 ! endosome organization GO:0007032 10 7 0,000 0,01551458 0,05374027 ! thyroid hormone generation GO:0006590 11 7 0,000 0,01551458 0,05365946 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,01551458 0,05357889 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,01551458 0,05349856 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,01551458 0,05341847 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01551458 0,05333863 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,01551458 0,05325902 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01551458 0,05317964 ! galactose metabolic process GO:0006012 10 7 0,000 0,01551458 0,05310051 ! intracellular pH reduction GO:0051452 10 7 0,000 0,01551458 0,05302161 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,01551458 0,05294294 ! organ growth GO:0035265 11 7 0,000 0,01551458 0,0528645 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,01551458 0,0527863 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,01551458 0,05270833 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,01551458 0,05263059 ! retinol metabolic process GO:0042572 9 7 0,000 0,01551458 0,05255308 ! behavioral fear response GO:0001662 13 7 0,000 0,01551458 0,05247579 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,01551458 0,05239874 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,01551458 0,05232191 ! rRNA modification GO:0000154 12 7 0,000 0,01551458 0,0522453 ! protein heterooligomerization GO:0051291 10 7 0,000 0,01551458 0,05216892 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01551458 0,05209276 ! response to UV-B GO:0010224 11 7 0,000 0,01551458 0,05201682 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,01551458 0,05194111 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,01551458 0,05186561 ! intermediate filament organization GO:0045109 11 7 0,000 0,01551458 0,05179033 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,01551458 0,05171528 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,01551458 0,05164043 ! fibrinolysis GO:0042730 9 7 0,000 0,01551458 0,05156581 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,01551458 0,0514914 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,01551458 0,0514172 ! B cell lineage commitment GO:0002326 17 7 0,000 0,01551458 0,05134322 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,01551458 0,05126945 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,01551458 0,0511959 ! response to tropane GO:0014073 13 7 0,000 0,01551458 0,05112255 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,01551458 0,05104941 ! melanosome localization GO:0032400 10 7 0,000 0,01551458 0,05097649 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,01551458 0,05090377 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,01551458 0,05083125 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,01551458 0,05075895 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,01551458 0,05068685 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,01551458 0,05061495 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,01551458 0,05054326 ! mast cell activation GO:0045576 9 7 0,000 0,01551458 0,05047177 ! multicellular organismal aging GO:0010259 11 7 0,000 0,01551458 0,05040048 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,01551458 0,05032939 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,01551458 0,05025851 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,01551458 0,05018782 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,01551458 0,05011733 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,01551458 0,05004704 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,01551458 0,04997695 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,01551458 0,04990705 ! T cell lineage commitment GO:0002360 12 7 0,000 0,01551458 0,04983735 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,01551458 0,04976784 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,01551458 0,04969852 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,01551458 0,0496294 ! regulation of lipid transport GO:0032368 13 7 0,000 0,01551458 0,04956047 ! response to tumor cell GO:0002347 12 7 0,000 0,01551458 0,04949173 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,01551458 0,04942319 ! neuroblast proliferation GO:0007405 13 7 0,000 0,01551458 0,04935483 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,01551458 0,04928666 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,01551458 0,04921868 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,01551458 0,04915088 ! diuresis GO:0030146 12 7 0,000 0,01551458 0,04908327 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,01551458 0,04901585 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,01551458 0,04894861 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01551458 0,04888156 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,01551458 0,04881469 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01551458 0,04874801 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01551458 0,0486815 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01551458 0,04861518 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,01551458 0,04854903 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,01551458 0,04848307 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,01551458 0,04841729 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,01551458 0,04835168 ! lymph node development GO:0048535 9 7 0,000 0,01551458 0,04828625 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,01551458 0,048221 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,01551458 0,04815592 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01551458 0,04809102 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,01551458 0,0480263 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,01551458 0,04796175 ! ATP catabolic process GO:0006200 10 7 0,000 0,01551458 0,04789737 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,01551458 0,04783316 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,01551458 0,04776913 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,01551458 0,04770527 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,01551458 0,04764158 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,01551458 0,04757805 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,01551458 0,0475147 ! muscle adaptation GO:0043500 12 7 0,000 0,01551458 0,04745152 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,01551458 0,0473885 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,01551458 0,04732565 ! retina homeostasis GO:0001895 9 7 0,000 0,01551458 0,04726297 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,01551458 0,04720045 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,01551458 0,0471381 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,01551458 0,04707591 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,01551458 0,04701389 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,01551458 0,04695203 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,01551458 0,04689033 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01551458 0,04682879 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,01645227 0,04959399 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,01771172 0,05332062 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,01771172 0,05325092 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,01771172 0,0531814 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,01771172 0,05311206 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,01771172 0,0530429 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,01771172 0,05297393 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,01771172 0,05290513 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,01771172 0,05283651 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,01771172 0,05276807 ! phosphate transport GO:0006817 10 8 0,000 0,01771172 0,05269981 ! N-glycan processing GO:0006491 12 8 0,000 0,01771172 0,05263172 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,01771172 0,05256381 ! UTP metabolic process GO:0046051 8 8 0,000 0,01771172 0,05249607 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,01771172 0,05242851 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,01771172 0,05236112 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,01771172 0,0522939 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,01771172 0,05222686 ! succinate metabolic process GO:0006105 14 8 0,000 0,01771172 0,05215999 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,01771172 0,05209329 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,01771172 0,05202676 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,01771172 0,0519604 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,01771172 0,0518942 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,01771172 0,05182818 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,01771172 0,05176233 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,01771172 0,05169664 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01771172 0,05163112 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,01771172 0,05156576 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,01771172 0,05150057 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,01771172 0,05143554 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,01771172 0,05137068 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,01771172 0,05130598 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,01771172 0,05124145 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,01771172 0,05117707 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,01771172 0,05111286 ! astrocyte differentiation GO:0048708 16 8 0,000 0,01771172 0,05104881 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,01771172 0,05098492 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,01771172 0,05092119 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,01771172 0,05085762 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,01771172 0,0507942 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,01771172 0,05073095 ! melanin metabolic process GO:0006582 12 8 0,000 0,01771172 0,05066785 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,01771172 0,05060491 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,01771172 0,05054212 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,01771172 0,05047949 ! macrophage activation GO:0042116 12 8 0,000 0,01771172 0,05041702 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,01771172 0,0503547 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,01771172 0,05029253 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,01771172 0,05023052 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,01771172 0,05016866 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01771172 0,05010695 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,01771172 0,05004539 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,01771172 0,04998399 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,01771172 0,04992273 ! ruffle organization GO:0031529 11 8 0,000 0,01771172 0,04986163 ! osteoblast development GO:0002076 13 8 0,000 0,01771172 0,04980067 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,01771172 0,04973987 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,01771172 0,04967921 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,01771172 0,0496187 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,01771172 0,04955833 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,01771172 0,04949812 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,01771172 0,04943805 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,01771172 0,04937812 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,01771172 0,04931834 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,01771172 0,04925871 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,01771172 0,04919922 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,01771172 0,04913987 ! oligodendrocyte development GO:0014003 8 8 0,000 0,01771172 0,04908066 ! segment specification GO:0007379 10 8 0,000 0,01771172 0,0490216 ! cellular extravasation GO:0045123 11 8 0,000 0,01771172 0,04896268 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,01771172 0,0489039 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,01771172 0,04884526 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,01771172 0,04878677 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,01771172 0,04872841 ! snRNA metabolic process GO:0016073 10 8 0,000 0,01771172 0,04867019 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,01771172 0,04861211 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,01771172 0,04855417 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,01771172 0,04849637 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,01771172 0,0484387 ! nucleosome disassembly GO:0006337 12 8 0,000 0,01771172 0,04838118 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,01771172 0,04832378 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,01771172 0,04826653 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,01771172 0,04820941 ! icosanoid secretion GO:0032309 12 8 0,000 0,01771172 0,04815242 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,01771172 0,04809557 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,01771172 0,04803886 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,01771172 0,04798227 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,01771172 0,04792582 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,01771172 0,04786951 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,01771172 0,04781332 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,01771172 0,04775727 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,01771172 0,04770135 ! sterol catabolic process GO:0016127 9 8 0,000 0,01771172 0,04764556 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,01771172 0,0475899 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,01771172 0,04753436 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,01771172 0,04747896 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,01771172 0,04742369 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,01771172 0,04736855 ! prophase GO:0051324 11 8 0,000 0,01771172 0,04731353 ! S phase GO:0051320 8 8 0,000 0,01771172 0,04725864 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,01771172 0,04720388 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,01771172 0,04714925 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,01771172 0,04709474 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,01771172 0,04704036 ! hormone catabolic process GO:0042447 13 8 0,000 0,01771172 0,0469861 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,01771172 0,04693197 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,01771172 0,04687796 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,01771172 0,04682408 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,01771172 0,04677032 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,01771172 0,04671669 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,01771172 0,04666317 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,01771172 0,04660978 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,01771172 0,04655651 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,01771172 0,04650337 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,01771172 0,04645034 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,01771172 0,04639744 ! lamellipodium assembly GO:0030032 9 8 0,000 0,01771172 0,04634465 ! regulation of embryonic development GO:0045995 16 8 0,000 0,01771172 0,04629199 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,01771172 0,04623944 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,01771172 0,04618702 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,01771172 0,04613471 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,01789078 0,04654842 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,01825851 0,04745149 ! peptidyl-amino acid modification GO:0018193 147 93 1,000 0,01825851 0,04739793 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,01938085 0,05025473 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,01938085 0,05019814 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,01990407 0,05149536 ! regulation of developmental growth GO:0048638 13 9 0,000 0,01990407 0,0514375 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,01990407 0,05137977 ! telencephalon cell migration GO:0022029 16 9 0,000 0,01990407 0,05132216 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,01990407 0,05126469 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,01990407 0,05120735 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,01990407 0,05115014 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,01990407 0,05109305 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,01990407 0,05103609 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,01990407 0,05097926 ! GTP metabolic process GO:0046039 9 9 0,000 0,01990407 0,05092255 ! elastic fiber assembly GO:0048251 13 9 0,000 0,01990407 0,05086597 ! social behavior GO:0035176 14 9 0,000 0,01990407 0,05080951 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,01990407 0,05075318 ! artery development GO:0060840 19 9 0,000 0,01990407 0,05069698 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,01990407 0,0506409 ! regulation of glycolysis GO:0006110 15 9 0,000 0,01990407 0,05058494 ! response to pain GO:0048265 16 9 0,000 0,01990407 0,05052911 ! protein complex disassembly GO:0043241 17 9 0,000 0,01990407 0,0504734 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,01990407 0,05041781 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,01990407 0,05036234 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,01990407 0,050307 ! lung alveolus development GO:0048286 17 9 0,000 0,01990407 0,05025178 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,01990407 0,05019668 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,01990407 0,0501417 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,01990407 0,05008684 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,01990407 0,0500321 ! ventral spinal cord development GO:0021517 11 9 0,000 0,01990407 0,04997748 ! protein targeting to ER GO:0045047 19 9 0,000 0,01990407 0,04992298 ! T cell selection GO:0045058 18 9 0,000 0,01990407 0,0498686 ! endoderm development GO:0007492 12 9 0,000 0,01990407 0,04981433 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,01990407 0,04976019 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,01990407 0,04970616 ! arginine catabolic process GO:0006527 10 9 0,000 0,01990407 0,04965225 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,01990407 0,04959845 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,01990407 0,04954477 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,01990407 0,04949121 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,01990407 0,04943777 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,01990407 0,04938443 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,01990407 0,04933122 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,01990407 0,04927812 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,01990407 0,04922513 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,01990407 0,04917226 ! mannose metabolic process GO:0006013 9 9 0,000 0,01990407 0,0491195 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,01990407 0,04906685 ! receptor clustering GO:0043113 15 9 0,000 0,01990407 0,04901432 ! epithelial cell development GO:0002064 10 9 0,000 0,01990407 0,04896189 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,01990407 0,04890958 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,01990407 0,04885739 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,01990407 0,0488053 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,01990407 0,04875332 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,01990407 0,04870146 ! motor axon guidance GO:0008045 14 9 0,000 0,01990407 0,0486497 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,01990407 0,04859806 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,01990407 0,04854652 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,01990407 0,0484951 ! blastoderm segmentation GO:0007350 11 9 0,000 0,01990407 0,04844378 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,01990407 0,04839257 ! DNA ligation GO:0006266 14 9 0,000 0,01990407 0,04834147 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,01990407 0,04829048 ! response to amine stimulus GO:0014075 13 9 0,000 0,01990407 0,04823959 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,01990407 0,04818881 ! erythrocyte development GO:0048821 11 9 0,000 0,01990407 0,04813814 ! renal water homeostasis GO:0003091 14 9 0,000 0,01990407 0,04808757 ! postreplication repair GO:0006301 11 9 0,000 0,01990407 0,04803712 ! mRNA cleavage GO:0006379 13 9 0,000 0,01990407 0,04798676 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,01990407 0,04793651 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,01990407 0,04788637 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,01990407 0,04783633 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,01990407 0,0477864 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,01990407 0,04773657 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,01990407 0,04768684 ! acid secretion GO:0046717 14 9 0,000 0,01990407 0,04763722 ! musculoskeletal movement GO:0050881 11 9 0,000 0,01990407 0,0475877 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,01990407 0,04753829 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,01990407 0,04748897 ! purine base metabolic process GO:0006144 18 9 0,000 0,01990407 0,04743976 ! oocyte differentiation GO:0009994 12 9 0,000 0,01990407 0,04739065 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,01990407 0,04734165 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,01990407 0,04729274 ! spleen development GO:0048536 15 9 0,000 0,01990407 0,04724393 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,01990407 0,04719523 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,01990407 0,04714662 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,01990407 0,04709812 ! detection of calcium ion GO:0005513 13 9 0,000 0,01990407 0,04704971 ! blastocyst formation GO:0001825 12 9 0,000 0,01990407 0,04700141 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,01990407 0,0469532 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,01990407 0,04690509 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,01990407 0,04685708 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,01990407 0,04680917 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,01990407 0,04676136 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,01990407 0,04671364 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,01990407 0,04666603 ! prepulse inhibition GO:0060134 14 9 0,000 0,01990407 0,0466185 ! embryonic placenta development GO:0001892 12 9 0,000 0,01990407 0,04657108 ! insulin secretion GO:0030073 17 9 0,000 0,01990407 0,04652375 ! sequestering of metal ion GO:0051238 11 9 0,000 0,01990407 0,04647652 ! response to nicotine GO:0035094 16 9 0,000 0,01990407 0,04642938 ! establishment of cell polarity GO:0030010 12 9 0,000 0,01990407 0,04638234 ! nucleus localization GO:0051647 15 9 0,000 0,01990407 0,0463354 ! regulation of synapse organization GO:0050807 12 9 0,000 0,01990407 0,04628855 ! calcium ion transport GO:0006816 167 99 1,000 0,02053163 0,04769975 ! regulation of translation GO:0006417 151 100 1,000 0,02092147 0,0485564 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,02092147 0,04850745 ! divalent metal ion transport GO:0070838 171 100 1,000 0,02092147 0,0484586 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02209166 0,05111753 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02209166 0,05106616 ! neuron fate specification GO:0048665 11 10 0,000 0,02209166 0,05101489 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02209166 0,05096372 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02209166 0,05091265 ! thyroid gland development GO:0030878 19 10 0,000 0,02209166 0,05086169 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02209166 0,05081083 ! synapsis GO:0007129 13 10 0,000 0,02209166 0,05076007 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02209166 0,05070941 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02209166 0,05065885 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02209166 0,05060839 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02209166 0,05055804 ! sulfate transport GO:0008272 12 10 0,000 0,02209166 0,05050778 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02209166 0,05045762 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02209166 0,05040757 ! androgen metabolic process GO:0008209 13 10 0,000 0,02209166 0,05035761 ! phospholipid efflux GO:0033700 16 10 0,000 0,02209166 0,05030775 ! hippocampus development GO:0021766 19 10 0,000 0,02209166 0,05025799 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02209166 0,05020833 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02209166 0,05015876 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02209166 0,0501093 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02209166 0,05005993 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02209166 0,05001066 ! pathogenesis GO:0009405 13 10 0,000 0,02209166 0,04996148 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02209166 0,0499124 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02209166 0,04986342 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02209166 0,04981453 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,02209166 0,04976574 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02209166 0,04971705 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02209166 0,04966845 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02209166 0,04961995 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02209166 0,04957154 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02209166 0,04952322 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02209166 0,049475 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02209166 0,04942687 ! response to X-ray GO:0010165 16 10 0,000 0,02209166 0,04937884 ! B cell proliferation GO:0042100 14 10 0,000 0,02209166 0,0493309 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02209166 0,04928305 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02209166 0,0492353 ! forebrain cell migration GO:0021885 17 10 0,000 0,02209166 0,04918763 ! lipid digestion GO:0044241 15 10 0,000 0,02209166 0,04914006 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02209166 0,04909259 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02209166 0,0490452 ! UV protection GO:0009650 14 10 0,000 0,02209166 0,0489979 ! entry into host cell GO:0030260 20 10 0,000 0,02209166 0,0489507 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02209166 0,04890359 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02209166 0,04885656 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02209166 0,04880963 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02209166 0,04876279 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,02209166 0,04871604 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02209166 0,04866937 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02209166 0,0486228 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02209166 0,04857632 ! regulation of organ growth GO:0046620 11 10 0,000 0,02209166 0,04852992 ! response to dsRNA GO:0043331 18 10 0,000 0,02209166 0,04848361 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02209166 0,04843739 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02209166 0,04839126 ! embryonic axis specification GO:0000578 12 10 0,000 0,02209166 0,04834522 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02209166 0,04829926 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02209166 0,0482534 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02209166 0,04820761 ! cranial nerve development GO:0021545 12 10 0,000 0,02209166 0,04816192 ! fucose catabolic process GO:0019317 16 10 0,000 0,02209166 0,04811631 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02209166 0,04807079 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02209166 0,04802535 ! protein sumoylation GO:0016925 12 10 0,000 0,02209166 0,04798001 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02209166 0,04793474 ! zymogen activation GO:0031638 14 10 0,000 0,02209166 0,04788956 ! salivary gland development GO:0007431 22 10 0,000 0,02209166 0,04784447 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02209166 0,04779946 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02209166 0,04775454 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02209166 0,0477097 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02209166 0,04766494 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02209166 0,04762027 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02209166 0,04757568 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02209166 0,04753117 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02209166 0,04748675 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02209166 0,04744241 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,02209166 0,04739816 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02209166 0,04735398 ! detection of bacterium GO:0016045 10 10 0,000 0,02209166 0,04730989 ! embryonic gut development GO:0048566 11 10 0,000 0,02209166 0,04726588 ! activation of innate immune response GO:0002218 10 10 0,000 0,02209166 0,04722196 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02209166 0,04717811 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02209166 0,04713435 ! developmental induction GO:0031128 13 10 0,000 0,02209166 0,04709066 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02209166 0,04704706 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,02209166 0,04700354 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02209166 0,0469601 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02209166 0,04691674 ! rRNA transcription GO:0009303 17 11 0,000 0,02427449 0,05150492 ! respiratory burst GO:0045730 14 11 0,000 0,02427449 0,05145745 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,02427449 0,05141007 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,02427449 0,05136278 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,02427449 0,05131557 ! virus-host interaction GO:0019048 17 11 0,000 0,02427449 0,05126845 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,02427449 0,05122141 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,02427449 0,05117446 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,02427449 0,0511276 ! RNA polyadenylation GO:0043631 19 11 0,000 0,02427449 0,05108082 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,02427449 0,05103413 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,02427449 0,05098752 ! mating GO:0007618 14 11 0,000 0,02427449 0,050941 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,02427449 0,05089456 ! T cell proliferation GO:0042098 20 11 0,000 0,02427449 0,05084821 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,02427449 0,05080194 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,02427449 0,05075576 ! bone resorption GO:0045453 16 11 0,000 0,02427449 0,05070966 ! regulated secretory pathway GO:0045055 14 11 0,000 0,02427449 0,05066365 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,02427449 0,05061771 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,02427449 0,05057186 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,02427449 0,0505261 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,02427449 0,05048041 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,02427449 0,05043481 ! syncytium formation GO:0006949 15 11 0,000 0,02427449 0,05038929 ! plasma membrane organization GO:0007009 18 11 0,000 0,02427449 0,05034386 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,02427449 0,0502985 ! focal adhesion formation GO:0048041 24 11 0,000 0,02427449 0,05025323 ! mitotic spindle organization GO:0007052 15 11 0,000 0,02427449 0,05020804 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,02427449 0,05016293 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,02427449 0,0501179 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,02427449 0,05007295 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,02427449 0,05002808 ! adult heart development GO:0007512 11 11 0,000 0,02427449 0,04998329 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,02427449 0,04993858 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,02427449 0,04989396 ! temperature homeostasis GO:0001659 16 11 0,000 0,02427449 0,04984941 ! L-glutamate transport GO:0015813 16 11 0,000 0,02427449 0,04980494 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,02427449 0,04976055 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,02427449 0,04971624 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,02427449 0,04967201 ! protein homotetramerization GO:0051289 18 11 0,000 0,02427449 0,04962786 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,02427449 0,04958378 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,02427449 0,04953978 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,02427449 0,04949587 ! vasoconstriction GO:0042310 15 11 0,000 0,02427449 0,04945203 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,02427449 0,04940826 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,02427449 0,04936458 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,02427449 0,04932097 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,02427449 0,04927744 ! ribosome assembly GO:0042255 13 11 0,000 0,02427449 0,04923398 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,02427449 0,04919061 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,02427449 0,0491473 ! chromatin silencing GO:0006342 19 11 0,000 0,02427449 0,04910408 ! nucleosome positioning GO:0016584 13 11 0,000 0,02427449 0,04906093 ! T cell homeostasis GO:0043029 20 11 0,000 0,02427449 0,04901786 ! regulation of isotype switching GO:0045191 19 11 0,000 0,02427449 0,04897486 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,02427449 0,04893193 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,02427449 0,04888909 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,02427449 0,04884631 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,02427449 0,04880362 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,02427449 0,04876099 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,02427449 0,04871844 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,02427449 0,04867597 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,02427449 0,04863357 ! male genitalia development GO:0030539 13 11 0,000 0,02427449 0,04859124 ! cholesterol efflux GO:0033344 19 11 0,000 0,02427449 0,04854899 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,02427449 0,04850681 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,02427449 0,0484647 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,02427449 0,04842267 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,02427449 0,04838071 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,02427449 0,04833882 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,02427449 0,048297 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,02427449 0,04825526 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,02427449 0,04821359 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,02427449 0,04817199 ! lysogeny GO:0030069 18 11 0,000 0,02427449 0,04813046 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,02427449 0,04808901 ! acrosome reaction GO:0007340 13 11 0,000 0,02427449 0,04804762 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,02427449 0,04800631 ! lactation GO:0007595 20 12 0,000 0,02645258 0,05226884 ! reproductive cellular process GO:0048610 14 12 0,000 0,02645258 0,05222397 ! tRNA modification GO:0006400 14 12 0,000 0,02645258 0,05217918 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,02645258 0,05213447 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,02645258 0,05208984 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,02645258 0,05204528 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,02645258 0,05200079 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,02645258 0,05195639 ! non-recombinational repair GO:0000726 19 12 0,000 0,02645258 0,05191206 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,02645258 0,0518678 ! peroxisomal transport GO:0043574 21 12 0,000 0,02645258 0,05182362 ! cartilage condensation GO:0001502 18 12 0,000 0,02645258 0,05177951 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,02645258 0,05173548 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,02645258 0,05169153 ! heart looping GO:0001947 15 12 0,000 0,02645258 0,05164765 ! palate development GO:0060021 15 12 0,000 0,02645258 0,05160384 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,02645258 0,05156011 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,02645258 0,05151645 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,02645258 0,05147287 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,02645258 0,05142936 ! arginine metabolic process GO:0006525 13 12 0,000 0,02645258 0,05138592 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,02645258 0,05134256 ! methionine metabolic process GO:0006555 13 12 0,000 0,02645258 0,05129927 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,02645258 0,05125605 ! Golgi organization GO:0007030 18 12 0,000 0,02645258 0,0512129 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,02645258 0,05116983 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,02645258 0,05112683 ! monoamine transport GO:0015844 13 12 0,000 0,02645258 0,0510839 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02645258 0,05104105 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,02645258 0,05099826 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,02645258 0,05095555 ! L-amino acid transport GO:0015807 20 12 0,000 0,02645258 0,05091291 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,02645258 0,05087034 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,02645258 0,05082784 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,02645258 0,05078542 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02645258 0,05074306 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,02645258 0,05070077 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,02645258 0,05065856 ! cerebellum development GO:0021549 13 12 0,000 0,02645258 0,05061641 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,02645258 0,05057434 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,02645258 0,05053233 ! histone acetylation GO:0016573 23 12 0,000 0,02645258 0,0504904 ! histone methylation GO:0016571 15 12 0,000 0,02645258 0,05044853 ! autonomic nervous system development GO:0048483 23 12 0,000 0,02645258 0,05040673 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,02645258 0,05036501 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,02645258 0,05032335 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,02645258 0,05028176 ! response to gamma radiation GO:0010332 20 12 0,000 0,02645258 0,05024024 ! regulation of epidermis development GO:0045682 17 12 0,000 0,02645258 0,05019879 ! intestinal absorption GO:0050892 19 12 0,000 0,02645258 0,0501574 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,02645258 0,05011609 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,02645258 0,05007484 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,02645258 0,05003366 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,02645258 0,04999255 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,02645258 0,0499515 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,02645258 0,04991052 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,02645258 0,04986961 ! microspike assembly GO:0030035 23 12 0,000 0,02645258 0,04982877 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,02645258 0,04978799 ! response to cold GO:0009409 14 12 0,000 0,02645258 0,04974728 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,02862592 0,05379054 ! cGMP metabolic process GO:0046068 16 13 0,000 0,02862592 0,05374663 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,02862592 0,05370279 ! water transport GO:0006833 17 13 0,000 0,02862592 0,05365903 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,02862592 0,05361533 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,02862592 0,0535717 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,02862592 0,05352815 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,02862592 0,05348467 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,02862592 0,05344125 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,02862592 0,05339791 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,02862592 0,05335464 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,02862592 0,05331144 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,02862592 0,0532683 ! response to hexose stimulus GO:0009746 19 13 0,000 0,02862592 0,05322524 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,02862592 0,05318225 ! glutamate metabolic process GO:0006536 18 13 0,000 0,02862592 0,05313933 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,02862592 0,05309647 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,02862592 0,05305369 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,02862592 0,05301097 ! NAD metabolic process GO:0019674 21 13 0,000 0,02862592 0,05296832 ! exocrine system development GO:0035272 27 13 0,000 0,02862592 0,05292574 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,02862592 0,05288323 ! bone mineralization GO:0030282 15 13 0,000 0,02862592 0,05284079 ! regulation of exocytosis GO:0017157 17 13 0,000 0,02862592 0,05279842 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,02862592 0,05275611 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,02862592 0,05271387 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,02862592 0,0526717 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,02862592 0,0526296 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,02862592 0,05258756 ! genitalia development GO:0048806 15 13 0,000 0,02862592 0,05254559 ! regulation of cellular pH GO:0030641 20 13 0,000 0,02862592 0,05250369 ! cellular pigmentation GO:0033059 24 13 0,000 0,02862592 0,05246185 ! tissue regeneration GO:0042246 21 13 0,000 0,02862592 0,05242008 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,02862592 0,05237838 ! cofactor transport GO:0051181 19 13 0,000 0,02862592 0,05233674 ! NADP metabolic process GO:0006739 18 13 0,000 0,02862592 0,05229517 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,02862592 0,05225367 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,02862592 0,05221223 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,02862592 0,05217086 ! gas transport GO:0015669 18 13 0,000 0,02862592 0,05212955 ! regulation of RNA stability GO:0043487 28 13 0,000 0,02862592 0,05208831 ! heme biosynthetic process GO:0006783 20 13 0,000 0,02862592 0,05204713 ! regulation of axon extension GO:0030516 23 13 0,000 0,02862592 0,05200602 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,02862592 0,05196498 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,02862592 0,05192399 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,02862592 0,05188308 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,02862592 0,05184222 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,02862592 0,05180144 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,02862592 0,05176071 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,03079454 0,05563821 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,03079454 0,05559454 ! superoxide anion generation GO:0042554 18 14 0,000 0,03079454 0,05555094 ! neuron maturation GO:0042551 21 14 0,000 0,03079454 0,0555074 ! regulation of S phase GO:0033261 18 14 0,000 0,03079454 0,05546394 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,03079454 0,05542054 ! myotube differentiation GO:0014902 21 14 0,000 0,03079454 0,05537721 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,03079454 0,05533394 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,03079454 0,05529075 ! inositol metabolic process GO:0006020 20 14 0,000 0,03079454 0,05524762 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,03079454 0,05520456 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,03079454 0,05516156 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,03079454 0,05511863 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,03079454 0,05507577 ! gene silencing by RNA GO:0031047 20 14 0,000 0,03079454 0,05503298 ! response to cAMP GO:0051591 19 14 0,000 0,03079454 0,05499025 ! limbic system development GO:0021761 25 14 0,000 0,03079454 0,05494759 ! startle response GO:0001964 21 14 0,000 0,03079454 0,054905 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,03079454 0,05486247 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,03079454 0,05482 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,03079454 0,05477761 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,03079454 0,05473527 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,03079454 0,05469301 ! glycine metabolic process GO:0006544 22 14 0,000 0,03079454 0,05465081 ! pituitary gland development GO:0021983 23 14 0,000 0,03079454 0,05460867 ! cellular response to starvation GO:0009267 21 14 0,000 0,03079454 0,0545666 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,03079454 0,05452459 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,03079454 0,05448265 ! regulation of heart rate GO:0002027 23 14 0,000 0,03079454 0,05444077 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,03079454 0,05439896 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,03079454 0,05435721 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,03079454 0,05431553 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,03079454 0,0542739 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,03079454 0,05423235 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,03079454 0,05419085 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,03079454 0,05414942 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,03079454 0,05410806 ! axon cargo transport GO:0008088 27 14 0,000 0,03079454 0,05406675 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,03079454 0,05402551 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,03079454 0,05398433 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,03079454 0,05394322 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,03079454 0,05390217 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03079454 0,05386118 ! mRNA splice site selection GO:0006376 26 14 0,000 0,03079454 0,05382025 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,03079454 0,05377938 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,03079454 0,05373858 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,03079454 0,05369784 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,03079454 0,05365716 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,03079454 0,05361654 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,03079454 0,05357598 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,03079454 0,05353548 ! muscle maintenance GO:0046716 19 14 0,000 0,03079454 0,05349505 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,03079454 0,05345468 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,03079454 0,05341436 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,03079454 0,05337411 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,03079454 0,05333392 ! cell killing GO:0001906 20 14 0,000 0,03079454 0,05329379 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,03079454 0,05325372 ! cilium assembly GO:0042384 20 14 0,000 0,03079454 0,05321371 ! peptide hormone secretion GO:0030072 23 14 0,000 0,03079454 0,05317376 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,03295844 0,05686753 ! positive regulation of cell size GO:0045793 20 15 0,000 0,03295844 0,0568249 ! metencephalon development GO:0022037 19 15 0,000 0,03295844 0,05678233 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,03295844 0,05673983 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,03295844 0,05669739 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,03295844 0,05665502 ! skin development GO:0043588 25 15 0,000 0,03295844 0,05661271 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,03295844 0,05657046 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,03295844 0,05652827 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,03295844 0,05648615 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,03295844 0,05644409 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,03295844 0,0564021 ! bile acid metabolic process GO:0008206 22 15 0,000 0,03295844 0,05636016 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,03295844 0,05631829 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,03295844 0,05627648 ! adult walking behavior GO:0007628 25 15 0,000 0,03295844 0,05623473 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,03295844 0,05619304 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,03295844 0,05615142 ! centrosome cycle GO:0007098 16 15 0,000 0,03295844 0,05610986 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,03295844 0,05606836 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,03295844 0,05602692 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,03295844 0,05598554 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,03295844 0,05594422 ! cerebral cortex development GO:0021987 29 15 0,000 0,03295844 0,05590296 ! response to osmotic stress GO:0006970 22 15 0,000 0,03295844 0,05586177 ! vesicle coating GO:0006901 25 15 0,000 0,03295844 0,05582063 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,03295844 0,05577956 ! DNA integration GO:0015074 22 15 0,000 0,03295844 0,05573854 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,03295844 0,05569759 ! peptide secretion GO:0002790 27 15 0,000 0,03295844 0,05565669 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,03295844 0,05561586 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,03295844 0,05557509 ! neuron recognition GO:0008038 22 15 0,000 0,03295844 0,05553437 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,03295844 0,05549372 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,03295844 0,05545312 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,03295844 0,05541259 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,03295844 0,05537211 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,03295844 0,05533169 ! biomineral formation GO:0031214 18 15 0,000 0,03295844 0,05529133 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,03295844 0,05525103 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,03295844 0,05521079 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,03295844 0,05517061 ! dopamine metabolic process GO:0042417 30 15 0,000 0,03295844 0,05513048 ! organic cation transport GO:0015695 19 15 0,000 0,03295844 0,05509042 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,03295844 0,05505041 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,03295844 0,05501046 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,03295844 0,05497057 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,03295844 0,05493074 ! defense response to virus GO:0051607 27 15 0,000 0,03295844 0,05489096 ! peptide hormone processing GO:0016486 19 15 0,000 0,03295844 0,05485124 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,03295844 0,05481158 ! protein secretion GO:0009306 27 16 0,000 0,03511763 0,05836023 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,03511763 0,05831809 ! hormone secretion GO:0046879 25 16 0,000 0,03511763 0,05827602 ! bone remodeling GO:0046849 24 16 0,000 0,03511763 0,058234 ! endothelial cell migration GO:0043542 22 16 0,000 0,03511763 0,05819205 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,03511763 0,05815015 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,03511763 0,05810832 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03511763 0,05806654 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,03511763 0,05802483 ! glial cell development GO:0021782 24 16 0,000 0,03511763 0,05798317 ! patterning of blood vessels GO:0001569 24 16 0,000 0,03511763 0,05794158 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,03511763 0,05790004 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,03511763 0,05785857 ! protein polyubiquitination GO:0000209 26 16 0,000 0,03511763 0,05781715 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,03511763 0,05777579 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,03511763 0,0577345 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,03511763 0,05769326 ! fructose metabolic process GO:0006000 20 16 0,000 0,03511763 0,05765208 ! regulation of protein binding GO:0043393 27 16 0,000 0,03511763 0,05761096 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,03511763 0,05756989 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,03511763 0,05752889 ! protein export from nucleus GO:0006611 24 16 0,000 0,03511763 0,05748794 ! negative regulation of immune response GO:0050777 28 16 0,000 0,03511763 0,05744706 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,03511763 0,05740623 ! DNA replication initiation GO:0006270 25 16 0,000 0,03511763 0,05736545 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,03511763 0,05732474 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,03511763 0,05728409 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,03511763 0,05724349 ! diencephalon development GO:0021536 25 16 0,000 0,03511763 0,05720295 ! oogenesis GO:0048477 23 16 0,000 0,03511763 0,05716246 ! neural crest cell migration GO:0001755 24 16 0,000 0,03511763 0,05712204 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,03511763 0,05708167 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,03511763 0,05704136 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,03511763 0,0570011 ! steroid catabolic process GO:0006706 22 16 0,000 0,03511763 0,0569609 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,03511763 0,05692076 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,03511763 0,05688068 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,03511763 0,05684065 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,03511763 0,05680068 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,03511763 0,05676076 ! sperm-egg recognition GO:0035036 16 16 0,000 0,03511763 0,0567209 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,03511763 0,05668109 ! nerve development GO:0021675 18 16 0,000 0,03511763 0,05664135 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,03511763 0,05660165 ! negative regulation of translation GO:0017148 22 16 0,000 0,03511763 0,05656202 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,03727213 0,05999013 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,03727213 0,05994818 ! negative regulation of defense response GO:0031348 19 17 0,000 0,03727213 0,05990629 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,03727213 0,05986445 ! glycerol metabolic process GO:0006071 20 17 0,000 0,03727213 0,05982268 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,03727213 0,05978096 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,03727213 0,0597393 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,03727213 0,0596977 ! signal complex assembly GO:0007172 29 17 0,000 0,03727213 0,05965616 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,03727213 0,05961467 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,03727213 0,05957324 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,03727213 0,05953187 ! memory GO:0007613 25 17 0,000 0,03727213 0,05949056 ! keratinization GO:0031424 17 17 0,000 0,03727213 0,05944931 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,03727213 0,05940811 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,03727213 0,05936697 ! retinoid metabolic process GO:0001523 22 17 0,000 0,03727213 0,05932588 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,03727213 0,05928485 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,03727213 0,05924388 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,03727213 0,05920297 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,03727213 0,05916211 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,03727213 0,05912131 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,03727213 0,05908056 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,03727213 0,05903988 ! membrane budding GO:0006900 29 17 0,000 0,03727213 0,05899924 ! heme metabolic process GO:0042168 27 17 0,000 0,03727213 0,05895866 ! actin filament bundle formation GO:0051017 26 17 0,000 0,03727213 0,05891814 ! neuromuscular junction development GO:0007528 23 17 0,000 0,03727213 0,05887768 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,03727213 0,05883727 ! body fluid secretion GO:0007589 27 17 0,000 0,03727213 0,05879691 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,03727213 0,05875661 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,03727213 0,05871637 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,03727213 0,05867618 ! sensory perception of pain GO:0019233 23 17 0,000 0,03727213 0,05863605 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,03727213 0,05859597 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,03727213 0,05855594 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,03727213 0,05851597 ! synaptogenesis GO:0007416 24 17 0,000 0,03727213 0,05847606 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,03727213 0,0584362 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,03727213 0,05839639 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,03727213 0,05835664 ! cell-cell junction organization GO:0045216 25 17 0,000 0,03727213 0,05831694 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,03727213 0,05827729 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,03727213 0,0582377 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,03727213 0,05819817 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,03727213 0,05815868 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,03727213 0,05811925 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,03727213 0,05807988 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,03942194 0,06138826 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,03942194 0,06134672 ! positive regulation of translation GO:0045727 28 18 0,000 0,03942194 0,06130524 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,03942194 0,06126382 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,03942194 0,06122246 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,03942194 0,06118114 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,03942194 0,06113989 ! cAMP metabolic process GO:0046058 33 18 0,000 0,03942194 0,06109869 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,03942194 0,06105755 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,03942194 0,06101646 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,03942194 0,06097542 ! axis specification GO:0009798 26 18 0,000 0,03942194 0,06093445 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,03942194 0,06089352 GO:0050886|endocrine process, ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,03942194 0,06085265 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,03942194 0,06081184 ! glutamine metabolic process GO:0006541 23 18 0,000 0,03942194 0,06077108 ! response to retinoic acid GO:0032526 25 18 0,000 0,03942194 0,06073038 ! pigmentation during development GO:0048066 31 18 0,000 0,03942194 0,06068973 ! central nervous system neuron development GO:0021954 30 18 0,000 0,03942194 0,06064913 ! fucose metabolic process GO:0006004 26 18 0,000 0,03942194 0,06060859 ! response to fungus GO:0009620 19 18 0,000 0,03942194 0,06056811 ! peptide cross-linking GO:0018149 31 18 0,000 0,03942194 0,06052767 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,03942194 0,0604873 ! heart process GO:0003015 27 18 0,000 0,03942194 0,06044697 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,03942194 0,0604067 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,03942194 0,06036648 ! visual learning GO:0008542 35 18 0,000 0,03942194 0,06032632 ! somitogenesis GO:0001756 24 18 0,000 0,03942194 0,06028621 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,03942194 0,06024615 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,03942194 0,06020615 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,03942194 0,0601662 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,03942194 0,0601263 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,03942194 0,06008645 ! vitamin transport GO:0051180 24 18 0,000 0,03942194 0,06004666 ! hormone transport GO:0009914 27 18 0,000 0,03942194 0,06000692 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,03942194 0,05996723 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,03942194 0,0599276 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,03942194 0,05988802 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,03942194 0,05984849 ! cell-cell recognition GO:0009988 20 18 0,000 0,03942194 0,05980901 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,03942194 0,05976958 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,03942194 0,05973021 ! regulation of glucose import GO:0046324 21 18 0,000 0,03942194 0,05969089 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,03942194 0,05965162 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,03942194 0,0596124 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,03942194 0,05957323 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,03942194 0,05953411 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,04156707 0,06273245 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,04156707 0,06269131 ! positive regulation of ossification GO:0045778 30 19 0,000 0,04156707 0,06265023 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,04156707 0,0626092 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,04156707 0,06256823 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,04156707 0,06252731 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,04156707 0,06248644 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,04156707 0,06244563 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,04156707 0,06240487 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,04156707 0,06236416 ! regeneration GO:0031099 32 19 0,000 0,04156707 0,0623235 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,04156707 0,0622829 ! response to alkaloid GO:0043279 32 19 0,000 0,04156707 0,06224235 ! sensory perception of taste GO:0050909 23 19 0,000 0,04156707 0,06220186 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,04156707 0,06216141 ! smooth muscle contraction GO:0006939 36 19 0,000 0,04156707 0,06212102 ! peroxisome organization GO:0007031 29 19 0,000 0,04156707 0,06208068 ! digestive system process GO:0022600 30 19 0,000 0,04156707 0,0620404 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,04156707 0,06200016 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,04156707 0,06195998 ! response to vitamin A GO:0033189 26 19 0,000 0,04156707 0,06191985 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,04156707 0,06187978 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,04156707 0,06183975 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,04156707 0,06179978 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,04156707 0,06175985 ! response to starvation GO:0042594 30 19 0,000 0,04156707 0,06171998 ! sex determination GO:0007530 29 19 0,000 0,04156707 0,06168016 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,04156707 0,0616404 ! plasma membrane fusion GO:0045026 23 19 0,000 0,04156707 0,06160068 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,04156707 0,06156101 ! cytolysis GO:0019835 20 19 0,000 0,04156707 0,0615214 ! renal system process GO:0003014 35 19 0,000 0,04156707 0,06148184 ! vasodilation GO:0042311 33 19 0,000 0,04156707 0,06144232 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,04156707 0,06140286 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,04156707 0,06136345 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,04156707 0,06132409 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,04156707 0,06128478 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,04156707 0,06124552 ! sarcomere organization GO:0045214 23 19 0,000 0,04156707 0,06120631 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,04156707 0,06116715 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,04156707 0,06112804 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,04156707 0,06108898 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,04156707 0,06104997 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,04156707 0,06101101 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,04156707 0,0609721 ! protein stabilization GO:0050821 26 19 0,000 0,04156707 0,06093324 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,04370753 0,06403014 ! iron ion transport GO:0006826 37 20 0,000 0,04370753 0,06398938 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,04370753 0,06394867 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,04370753 0,06390802 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,04370753 0,06386742 ! response to vitamin GO:0033273 29 20 0,000 0,04370753 0,06382687 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,04370753 0,06378637 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,04370753 0,06374592 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,04370753 0,06370552 ! spinal cord development GO:0021510 31 20 0,000 0,04370753 0,06366518 ! response to ethanol GO:0045471 37 20 0,000 0,04370753 0,06362488 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,04370753 0,06358464 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,04370753 0,06354445 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,04370753 0,06350431 ! chromosome condensation GO:0030261 31 20 0,000 0,04370753 0,06346421 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,04370753 0,06342417 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,04370753 0,06338418 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,04370753 0,06334424 ! pallium development GO:0021543 38 20 0,000 0,04370753 0,06330436 ! DNA modification GO:0006304 28 20 0,000 0,04370753 0,06326452 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,04370753 0,06322473 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,04370753 0,06318499 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,04370753 0,0631453 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,04370753 0,06310566 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,04370753 0,06306607 ! collagen catabolic process GO:0030574 25 20 0,000 0,04370753 0,06302653 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,04370753 0,06298704 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,04370753 0,0629476 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,04370753 0,06290821 ! alditol metabolic process GO:0019400 24 20 0,000 0,04370753 0,06286887 ! actin filament-based movement GO:0030048 34 20 0,000 0,04370753 0,06282957 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,04584333 0,06585863 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,04584333 0,06581752 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,04584333 0,06577646 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,04584333 0,06573545 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,04584333 0,0656945 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,04584333 0,06565359 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,04584333 0,06561273 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,04584333 0,06557193 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,04584333 0,06553118 GO:0034105|positive regulation of tissue remodeling, ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,04584333 0,06549048 ! protein amino acid acylation GO:0043543 37 21 0,000 0,04584333 0,06544982 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,04584333 0,06540922 ! phototransduction GO:0007602 25 21 0,000 0,04584333 0,06536867 ! dendrite development GO:0016358 35 21 0,000 0,04584333 0,06532817 ! visual behavior GO:0007632 39 21 0,000 0,04584333 0,06528772 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,04584333 0,06524732 ! ovarian follicle development GO:0001541 30 21 0,000 0,04584333 0,06520697 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,04584333 0,06516667 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,04584333 0,06512641 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,04584333 0,06508621 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,04584333 0,06504606 ! cell aging GO:0007569 32 21 0,000 0,04584333 0,06500596 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,04584333 0,06496591 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,04584333 0,0649259 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,04584333 0,06488595 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,04584333 0,06484604 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,04584333 0,06480619 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,04584333 0,06476638 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,04584333 0,06472662 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,04584333 0,06468691 ! fatty acid transport GO:0015908 30 21 0,000 0,04584333 0,06464725 ! immunoglobulin production GO:0002377 33 21 0,000 0,04584333 0,06460764 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,04584333 0,06456807 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,04584333 0,06452856 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,04584333 0,06448909 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,04584333 0,06444967 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,04584333 0,0644103 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,04584333 0,06437098 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,04584333 0,06433171 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,04584333 0,06429248 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,04584333 0,0642533 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,04584333 0,06421417 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,04584333 0,06417509 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,04584333 0,06413605 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,04584333 0,06409706 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,04797449 0,06703604 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,04797449 0,06699534 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,04797449 0,06695469 ! viral genome replication GO:0019079 29 22 0,000 0,04797449 0,06691408 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,04797449 0,06687353 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,04797449 0,06683302 ! leukocyte adhesion GO:0007159 38 22 0,000 0,04797449 0,06679257 ! molting cycle process GO:0022404 40 22 0,000 0,04797449 0,06675216 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,04797449 0,0667118 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,04797449 0,06667149 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,04797449 0,06663123 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,04797449 0,06659102 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,04797449 0,06655086 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,04797449 0,06651074 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,04797449 0,06647068 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,04797449 0,06643066 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 37 22 0,000 0,04797449 0,06639069 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,04797449 0,06635077 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,04797449 0,06631089 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,04797449 0,06627107 ! regulation of behavior GO:0050795 38 22 0,000 0,04797449 0,06623129 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,04797449 0,06619156 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,04797449 0,06615187 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,04797449 0,06611224 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,04797449 0,06607265 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,04797449 0,06603311 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,04797449 0,06599361 ! blastocyst development GO:0001824 37 22 0,000 0,04797449 0,06595417 ! neural tube closure GO:0001843 33 22 0,000 0,04797449 0,06591477 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,04797449 0,06587542 ! protein tetramerization GO:0051262 39 22 0,000 0,04797449 0,06583611 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,05010101 0,06871337 ! neuron fate commitment GO:0048663 32 23 0,000 0,05010101 0,06867242 ! embryonic pattern specification GO:0009880 31 23 0,000 0,05010101 0,06863151 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,05010101 0,06859066 ! myelination GO:0042552 35 23 0,000 0,05010101 0,06854986 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,05010101 0,0685091 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,05010101 0,0684684 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,05010101 0,06842774 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,05010101 0,06838713 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,05010101 0,06834657 ! vesicle targeting GO:0006903 32 23 0,000 0,05010101 0,06830605 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,05010101 0,06826559 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,05010101 0,06822517 ! osteoblast differentiation GO:0001649 40 23 0,000 0,05010101 0,0681848 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,05010101 0,06814448 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,05010101 0,0681042 ! interaction with host GO:0051701 37 23 0,000 0,05010101 0,06806398 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,05010101 0,0680238 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,05010101 0,06798367 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,05010101 0,06794358 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,05010101 0,06790354 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,05010101 0,06786355 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,05010101 0,06782361 ! pentose metabolic process GO:0019321 31 23 0,000 0,05010101 0,06778371 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,05010101 0,06774386 ! spermatid development GO:0007286 33 23 0,000 0,05010101 0,06770406 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,05010101 0,06766431 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,05010101 0,0676246 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,05010101 0,06758493 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,05010101 0,06754532 ! telomere organization GO:0032200 32 23 0,000 0,05010101 0,06750575 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,05010101 0,06746623 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,05010101 0,06742675 ! regulation of amine transport GO:0051952 38 23 0,000 0,05010101 0,06738732 ! liver development GO:0001889 40 23 0,000 0,05010101 0,06734793 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,05222289 0,07015926 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,05222289 0,07011831 ! initiation of viral infection GO:0019059 42 24 0,000 0,05222289 0,0700774 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,05222289 0,07003654 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,05222289 0,06999572 ! superoxide metabolic process GO:0006801 32 24 0,000 0,05222289 0,06995496 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,05222289 0,06991424 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,05222289 0,06987356 ! sperm motility GO:0030317 27 24 0,000 0,05222289 0,06983294 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,05222289 0,06979236 ! vacuole organization GO:0007033 39 24 0,000 0,05222289 0,06975183 ! receptor metabolic process GO:0043112 37 24 0,000 0,05222289 0,06971135 ! neural crest cell development GO:0014032 39 24 0,000 0,05222289 0,06967092 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,05222289 0,06963053 ! primary neural tube formation GO:0014020 35 24 0,000 0,05222289 0,06959018 ! negative regulation of cell development GO:0010721 56 24 0,000 0,05222289 0,06954989 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,05222289 0,06950964 ! base-excision repair GO:0006284 31 24 0,000 0,05222289 0,06946944 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,05222289 0,06942928 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,05222289 0,06938917 ! glutathione metabolic process GO:0006749 29 24 0,000 0,05222289 0,06934911 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,05222289 0,06930909 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,05222289 0,06926912 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,05222289 0,0692292 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,05434017 0,07199446 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,05434017 0,07195301 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,05434017 0,07191161 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,05434017 0,07187026 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,05434017 0,07182895 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,05434017 0,0717877 ! peptide transport GO:0015833 43 25 0,000 0,05434017 0,07174649 ! male gonad development GO:0008584 33 25 0,000 0,05434017 0,07170532 ! iron ion homeostasis GO:0055072 39 25 0,000 0,05434017 0,07166421 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,05434017 0,07162314 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,05434017 0,07158212 ! phospholipid transport GO:0015914 35 25 0,000 0,05434017 0,07154114 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,05434017 0,07150022 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,05434017 0,07145934 ! detection of light stimulus GO:0009583 30 25 0,000 0,05434017 0,0714185 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,05434017 0,07137772 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,05434017 0,07133698 ! leukocyte proliferation GO:0070661 39 25 0,000 0,05434017 0,07129628 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,05434017 0,07125563 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,05645283 0,07398376 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,05645283 0,07394163 ! translational initiation GO:0006413 43 26 0,000 0,05645283 0,07389955 ! regulation of pH GO:0006885 36 26 0,000 0,05645283 0,07385751 ! circadian rhythm GO:0007623 42 26 0,000 0,05645283 0,07381552 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,05645283 0,07377358 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,05645283 0,07373169 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,05645283 0,07368984 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,05645283 0,07364804 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,05645283 0,07360629 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,05645283 0,07356459 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,05645283 0,07352293 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,05856089 0,07622527 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,05856089 0,07618215 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,05856089 0,07613909 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,05856089 0,07609607 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,05856089 0,0760531 ! catechol metabolic process GO:0009712 43 27 0,000 0,05856089 0,07601018 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,05856089 0,07596731 ! acute-phase response GO:0006953 42 27 0,000 0,05856089 0,07592449 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,05856089 0,07588172 ! myofibril assembly GO:0030239 36 27 0,000 0,05856089 0,07583899 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,05856089 0,07579631 ! response to ionizing radiation GO:0010212 47 27 0,000 0,05856089 0,07575368 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,05856089 0,0757111 ! natural killer cell activation GO:0030101 35 27 0,000 0,05856089 0,07566857 ! lipid oxidation GO:0034440 38 27 0,000 0,05856089 0,07562608 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,05856089 0,07558364 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,05856089 0,07554125 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,05856089 0,0754989 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,05856089 0,07545661 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,05856089 0,07541436 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,05856089 0,07537216 ! gene silencing GO:0016458 41 27 0,000 0,05856089 0,07533 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,06066436 0,07799219 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,06066436 0,07794862 ! phenol metabolic process GO:0018958 44 28 0,000 0,06066436 0,0779051 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,06066436 0,07786163 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,06066436 0,0778182 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,06066436 0,07777482 ! cell junction assembly GO:0034329 56 28 0,000 0,06066436 0,0777315 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,06066436 0,07768822 ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,06066436 0,07764498 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,06066436 0,0776018 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,06066436 0,07755866 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,06066436 0,07751557 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,06066436 0,07747253 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,06066436 0,07742954 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,06066436 0,0773866 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,06066436 0,0773437 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,06066436 0,07730085 ! ensheathment of neurons GO:0007272 43 28 0,000 0,06066436 0,07725805 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,06066436 0,07721529 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,06066436 0,07717259 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,06066436 0,07712992 ! neural tube formation GO:0001841 41 28 0,000 0,06066436 0,07708731 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,06066436 0,07704475 ! placenta development GO:0001890 37 28 0,000 0,06066436 0,07700223 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,06276326 0,07962244 ! regulation of innate immune response GO:0045088 38 29 0,000 0,06276326 0,07957855 ! ovulation cycle process GO:0022602 41 29 0,000 0,06276326 0,07953471 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,06276326 0,07949091 ! protein targeting to membrane GO:0006612 53 29 0,000 0,06276326 0,07944716 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,06276326 0,07940346 ! mismatch repair GO:0006298 34 29 0,000 0,06276326 0,07935981 ! muscle cell development GO:0055001 38 29 0,000 0,06276326 0,0793162 ! telencephalon development GO:0021537 52 29 0,000 0,06276326 0,07927265 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,06276326 0,07922914 ! eye morphogenesis GO:0048592 51 29 0,000 0,06276326 0,07918568 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,06276326 0,07914226 ! tissue homeostasis GO:0001894 42 29 0,000 0,06276326 0,0790989 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,06485758 0,08169356 ! collagen metabolic process GO:0032963 40 30 0,000 0,06485758 0,08164884 ! organic anion transport GO:0015711 51 30 0,000 0,06485758 0,08160418 ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,06485758 0,08155956 ! spliceosome assembly GO:0000245 49 30 0,000 0,06485758 0,08151499 ! spindle organization GO:0007051 37 30 0,000 0,06485758 0,08147047 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,06485758 0,081426 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,06485758 0,08138158 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,06485758 0,08133721 ! ceramide metabolic process GO:0006672 43 30 0,000 0,06485758 0,08129288 ! ovulation cycle GO:0042698 43 30 0,000 0,06485758 0,0812486 ! hindbrain development GO:0030902 45 30 0,000 0,06485758 0,08120437 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,06485758 0,08116019 ! adult locomotory behavior GO:0008344 47 30 0,000 0,06485758 0,08111606 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,06485758 0,08107198 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,06485758 0,08102794 ! response to heat GO:0009408 41 30 0,000 0,06485758 0,08098395 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,06485758 0,08094001 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,06485758 0,08089611 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,06694734 0,08345739 ! negative regulation of secretion GO:0051048 49 31 0,000 0,06694734 0,08341218 ! glial cell differentiation GO:0010001 55 31 0,000 0,06694734 0,08336702 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,06694734 0,08332191 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,06694734 0,08327685 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,06694734 0,08323183 ! odontogenesis GO:0042476 50 31 0,000 0,06694734 0,08318687 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,06694734 0,08314195 ! segmentation GO:0035282 41 31 0,000 0,06694734 0,08309708 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,06694734 0,08305226 ! metanephros development GO:0001656 58 31 0,000 0,06694734 0,08300749 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,06694734 0,08296276 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,06694734 0,08291809 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,06694734 0,08287346 ! cell fate specification GO:0001708 37 31 0,000 0,06694734 0,08282888 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,06694734 0,08278435 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,06694734 0,08273987 ! RNA modification GO:0009451 40 31 0,000 0,06694734 0,08269543 ! regulation of muscle development GO:0048634 48 32 0,000 0,06903256 0,08522538 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,06903256 0,08517966 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,06903256 0,08513398 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,06903256 0,08508836 ! meiosis I GO:0007127 52 32 0,000 0,06903256 0,08504279 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,06903256 0,08499726 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,06903256 0,08495178 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,06903256 0,08490635 ! peripheral nervous system development GO:0007422 53 32 0,000 0,06903256 0,08486097 ! regulation of protein stability GO:0031647 48 32 0,000 0,06903256 0,08481564 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,06903256 0,08477036 ! cytokine production GO:0001816 44 32 0,000 0,06903256 0,08472512 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,06903256 0,08467994 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,06903256 0,0846348 ! vesicle localization GO:0051648 47 32 0,000 0,06903256 0,08458971 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,07111323 0,08709288 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,07111323 0,08704653 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,07111323 0,08700023 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,07111323 0,08695397 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,07111323 0,08690777 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,07111323 0,08686162 ! sister chromatid segregation GO:0000819 46 33 0,000 0,07111323 0,08681551 ! ear morphogenesis GO:0042471 42 33 0,000 0,07111323 0,08676946 ! actomyosin structure organization GO:0031032 43 33 0,000 0,07111323 0,08672345 ! cell junction organization GO:0034330 63 33 0,000 0,07111323 0,08667749 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,07111323 0,08663158 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,07111323 0,08658572 ! nucleus organization GO:0006997 49 33 0,000 0,07111323 0,08653991 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,07111323 0,08649414 ! female gonad development GO:0008585 49 33 0,000 0,07111323 0,08644843 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,07111323 0,08640276 ! positive regulation of cell development GO:0010720 54 33 0,000 0,07111323 0,08635714 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,07111323 0,08631157 ! regulation of proteolysis GO:0030162 50 33 0,000 0,07111323 0,08626605 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,07111323 0,08622057 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,07111323 0,08617515 ! cytokinesis GO:0000910 52 33 0,000 0,07111323 0,08612977 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,07111323 0,08608444 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,07318937 0,08855105 ! mRNA catabolic process GO:0006402 48 34 0,000 0,07318937 0,0885045 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,07318937 0,08845799 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,07318937 0,08841153 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,07318937 0,08836512 ! feeding behavior GO:0007631 45 34 0,000 0,07318937 0,08831876 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,07318937 0,08827244 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,07318937 0,08822618 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,07318937 0,08817996 ! neuron migration GO:0001764 46 34 0,000 0,07318937 0,0881338 ! female gamete generation GO:0007292 43 34 0,000 0,07318937 0,08808768 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,07318937 0,08804161 ! polyol metabolic process GO:0019751 44 34 0,000 0,07318937 0,08799558 ! aerobic respiration GO:0009060 47 34 0,000 0,07318937 0,08794961 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,07318937 0,08790368 ! embryonic organ development GO:0048568 45 34 0,000 0,07318937 0,0878578 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,07318937 0,08781197 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,07526099 0,0902504 ! Notch signaling pathway GO:0007219 56 35 0,000 0,07526099 0,09020337 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,07526099 0,09015639 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,07526099 0,09010946 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,07526099 0,09006258 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,07526099 0,09001574 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,07526099 0,08996896 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,07526099 0,08992222 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,07526099 0,08987553 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,07526099 0,08982889 ! glycogen metabolic process GO:0005977 48 35 0,000 0,07526099 0,0897823 ! pigment metabolic process GO:0042440 61 35 0,000 0,07526099 0,08973576 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,0773281 0,09215265 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,0773281 0,09210493 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,0773281 0,09205726 ! negative regulation of binding GO:0051100 58 36 0,000 0,0773281 0,09200963 ! neural tube development GO:0021915 50 36 0,000 0,0773281 0,09196206 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,0773281 0,09191453 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,0773281 0,09186706 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,0773281 0,09181963 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,0773281 0,09177225 ! glucan metabolic process GO:0044042 49 36 0,000 0,0773281 0,09172492 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,0793907 0,094123 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,0793907 0,0940745 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,0793907 0,09402606 ! learning GO:0007612 67 37 0,000 0,0793907 0,09397767 ! ion transmembrane transport GO:0034220 56 37 0,000 0,0793907 0,09392933 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,0793907 0,09388104 ! regulation of protein secretion GO:0050708 51 37 0,000 0,0793907 0,09383279 ! amino acid activation GO:0043038 52 37 0,000 0,0793907 0,0937846 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,0793907 0,09373645 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,08144881 0,09611712 ! gliogenesis GO:0042063 71 38 0,000 0,08144881 0,09606783 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,08144881 0,09601859 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,08144881 0,0959694 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,08144881 0,09592026 ! phagocytosis GO:0006909 60 38 0,000 0,08144881 0,09587117 ! pigmentation GO:0043473 74 38 0,000 0,08144881 0,09582213 ! maintenance of location in cell GO:0051651 69 38 0,000 0,08144881 0,09577314 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,08350244 0,09813777 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,08350244 0,09808765 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,08350244 0,09803758 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,08350244 0,09798756 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,08350244 0,09793759 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,08350244 0,09788767 ! male sex differentiation GO:0046661 53 39 0,000 0,08350244 0,09783781 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,08350244 0,09778799 ! chromatin remodeling GO:0006338 68 39 0,000 0,08350244 0,09773823 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,08350244 0,09768851 ! JNK cascade GO:0007254 54 39 0,000 0,08350244 0,09763885 ! developmental growth GO:0048589 62 39 0,000 0,08350244 0,09758924 ! cell growth GO:0016049 61 39 0,000 0,08350244 0,09753967 ! synapse organization GO:0050808 55 39 0,000 0,08350244 0,09749016 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,0855516 0,0998319 ! response to calcium ion GO:0051592 58 40 0,000 0,0855516 0,09978127 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,0855516 0,0997307 ! regulation of tube size GO:0035150 60 40 0,000 0,0855516 0,09968018 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,0855516 0,09962971 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,0855516 0,09957929 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,0855516 0,09952892 ! peptide metabolic process GO:0006518 56 40 0,000 0,0855516 0,0994786 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,0855516 0,09942833 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,0855516 0,09937812 ! double-strand break repair GO:0006302 67 40 0,000 0,0855516 0,09932795 ! B cell differentiation GO:0030183 62 40 0,000 0,0855516 0,09927784 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,0855516 0,09922777 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,08759629 0,10154811 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,08759629 0,10149696 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,08759629 0,10144585 ! glucose transport GO:0015758 52 41 0,000 0,08759629 0,1013948 ! endosome transport GO:0016197 71 41 0,000 0,08759629 0,10134379 ! striated muscle contraction GO:0006941 62 41 0,000 0,08759629 0,10129284 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,08759629 0,10124194 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,08759629 0,10119109 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,08759629 0,10114029 ! biopolymer methylation GO:0043414 62 41 0,000 0,08759629 0,10108954 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,08759629 0,10103885 ! mitochondrial transport GO:0006839 60 42 0,000 0,08963652 0,10334035 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,08963652 0,10328858 ! cellular component disassembly GO:0022411 64 42 0,000 0,08963652 0,10323686 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,08963652 0,10318519 ! hexose transport GO:0008645 54 42 0,000 0,08963652 0,10313357 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,08963652 0,103082 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,08963652 0,10303049 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,08963652 0,10297902 ! excretion GO:0007588 63 42 0,000 0,08963652 0,10292761 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,08963652 0,10287625 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,08963652 0,10282494 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,08963652 0,10277368 ! regulation of cell shape GO:0008360 78 42 0,000 0,08963652 0,10272247 ! positive regulation of binding GO:0051099 59 43 0,000 0,09167231 0,10500315 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,09167231 0,10495088 ! leukocyte migration GO:0050900 60 43 0,000 0,09167231 0,10489867 ! neuromuscular process GO:0050905 79 43 0,000 0,09167231 0,1048465 ! activation of caspase activity GO:0006919 65 43 0,000 0,09167231 0,10479439 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,09167231 0,10474233 ! tRNA processing GO:0008033 49 43 0,000 0,09167231 0,10469033 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,09167231 0,10463837 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,09167231 0,10458647 ! methylation GO:0032259 64 43 0,000 0,09167231 0,10453461 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,09370367 0,10679803 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,09370367 0,10674514 ! glycolysis GO:0006096 53 44 0,000 0,09370367 0,10669229 ! regulation of action potential GO:0001508 71 44 0,000 0,09370367 0,1066395 ! regulation of ion transport GO:0043269 57 44 0,000 0,09370367 0,10658676 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,09370367 0,10653407 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,09370367 0,10648144 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,09370367 0,10642886 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,09370367 0,10637632 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,09370367 0,10632384 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,09370367 0,10627142 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,09370367 0,10621904 ! RNA catabolic process GO:0006401 64 45 0,000 0,09573059 0,10846323 ! positive regulation of defense response GO:0031349 59 45 0,000 0,09573059 0,10840983 ! regulation of translational initiation GO:0006446 64 45 0,000 0,09573059 0,10835648 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,09573059 0,10830318 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,09573059 0,10824993 ! cell recognition GO:0008037 58 45 0,000 0,09573059 0,10819674 ! cell maturation GO:0048469 60 45 0,000 0,09573059 0,1081436 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,0977531 0,11037415 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,0977531 0,11031999 ! cell redox homeostasis GO:0045454 63 46 0,000 0,0977531 0,11026588 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,0977531 0,11021183 ! regulation of ossification GO:0030278 71 46 0,000 0,0977531 0,11015783 ! histone modification GO:0016570 68 46 0,000 0,0977531 0,11010389 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,0977531 0,11004999 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,09977121 0,11226701 ! viral infectious cycle GO:0019058 71 47 0,000 0,09977121 0,11221211 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,09977121 0,11215727 ! endocrine system development GO:0035270 83 47 0,000 0,09977121 0,11210248 ! covalent chromatin modification GO:0016569 75 47 0,000 0,09977121 0,11204774 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,09977121 0,11199306 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,09977121 0,11193843 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,09977121 0,11188385 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,09977121 0,11182932 ! chloride transport GO:0006821 67 48 0,000 0,10178491 0,11403083 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,10178491 0,11397531 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,10178491 0,11391985 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,10178491 0,11386444 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,10178491 0,11380909 ! heart morphogenesis GO:0003007 65 48 0,000 0,10178491 0,11375379 ! regulation of DNA replication GO:0006275 75 48 0,000 0,10178491 0,11369854 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,10178491 0,11364335 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,10178491 0,11358821 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,10178491 0,11353312 ! regulation of endocytosis GO:0030100 63 48 0,000 0,10178491 0,11347809 ! nuclear export GO:0051168 69 48 0,000 0,10178491 0,11342311 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,10178491 0,11336818 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,10178491 0,11331331 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,10379422 0,1154943 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,10379422 0,11543845 ! sensory perception of smell GO:0007608 61 49 0,000 0,10379422 0,11538266 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,10379422 0,11532692 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,10379422 0,11527123 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,10379422 0,1152156 ! germ cell development GO:0007281 68 49 0,000 0,10379422 0,11516002 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,10379422 0,11510449 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,10379422 0,11504902 ! cartilage development GO:0051216 70 49 0,000 0,10379422 0,1149936 ! maintenance of location GO:0051235 84 49 0,000 0,10379422 0,11493824 ! regulation of actin filament length GO:0030832 72 50 0,000 0,10579916 0,11710205 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,10579916 0,11704573 ! positive regulation of growth GO:0045927 67 50 0,000 0,10579916 0,11698945 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,10579916 0,11693324 ! proton transport GO:0015992 75 50 0,000 0,10579916 0,11687707 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,10579916 0,11682096 ! hydrogen transport GO:0006818 77 51 0,000 0,10779972 0,11897282 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,10779972 0,11891576 ! adult behavior GO:0030534 80 51 0,000 0,10779972 0,11885875 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,10779972 0,1188018 ! transition metal ion transport GO:0000041 74 52 0,000 0,10979593 0,12094379 ! regulation of cellular component size GO:0032535 74 52 0,000 0,10979593 0,12088589 ! aging GO:0007568 79 52 0,000 0,10979593 0,12082805 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,10979593 0,12077027 ! establishment of organelle localization GO:0051656 85 52 0,000 0,10979593 0,12071254 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,11178778 0,12284371 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,11178778 0,12278505 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,11178778 0,12272644 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,11178778 0,12266788 ! kidney development GO:0001822 90 53 0,000 0,11178778 0,12260939 ! single fertilization GO:0007338 59 53 0,000 0,11178778 0,12255095 ! cell projection assembly GO:0030031 76 53 0,000 0,11178778 0,12249256 ! amino acid transport GO:0006865 84 54 0,000 0,11377528 0,12461103 ! regulation of mitosis GO:0007088 84 54 0,000 0,11377528 0,12455171 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,11377528 0,12449246 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,11377528 0,12443326 ! detection of external stimulus GO:0009581 66 54 0,000 0,11377528 0,12437412 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,11377528 0,12431504 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,11377528 0,12425601 ! exocytosis GO:0006887 74 55 0,000 0,11575846 0,12636187 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,11575846 0,12630192 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,11575846 0,12624204 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,11773731 0,12833925 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,11773731 0,12827845 ! carbohydrate transport GO:0008643 74 57 0,000 0,11971184 0,13036801 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,11971184 0,13030631 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,11971184 0,13024467 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,11971184 0,13018309 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,11971184 0,13012157 ! secondary metabolic process GO:0019748 84 57 0,000 0,11971184 0,1300601 ! developmental maturation GO:0021700 75 57 0,000 0,11971184 0,1299987 ! gonad development GO:0008406 79 57 0,000 0,11971184 0,12993735 ! viral reproductive process GO:0022415 87 58 0,000 0,12168207 0,13201357 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,12168207 0,13195133 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,12168207 0,13188914 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,123648 0,13395686 ! activation of MAPK activity GO:0000187 84 59 0,000 0,123648 0,13389379 ! actin filament organization GO:0007015 95 59 0,000 0,123648 0,13383078 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,123648 0,13376783 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,12560965 0,13582614 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,12560965 0,13576231 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,12560965 0,13569854 ! regulation of heart contraction GO:0008016 91 60 0,000 0,12560965 0,13563483 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,12560965 0,13557118 ! fertilization GO:0009566 68 60 0,000 0,12560965 0,13550759 ! regulation of homeostatic process GO:0032844 105 60 0,000 0,12560965 0,13544407 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,12756701 0,13749022 ! meiosis GO:0007126 96 61 0,000 0,12756701 0,13742582 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 0,000 0,12756701 0,13736149 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,12756701 0,13729721 ! urogenital system development GO:0001655 101 61 0,000 0,12756701 0,13723299 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,12756701 0,13716883 ! extracellular matrix organization GO:0030198 103 61 0,000 0,12756701 0,13710473 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,12756701 0,1370407 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,12756701 0,13697672 ! amine catabolic process GO:0009310 90 62 0,000 0,12952011 0,13900898 ! neurotransmitter transport GO:0006836 81 62 0,000 0,12952011 0,13894415 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,12952011 0,13887937 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,12952011 0,13881466 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,12952011 0,13875 ! meiotic cell cycle GO:0051321 97 62 0,000 0,12952011 0,13868541 ! organelle localization GO:0051640 96 62 0,000 0,12952011 0,13862087 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,13146895 0,1406412 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,13146895 0,14057581 ! viral reproduction GO:0016032 92 63 0,000 0,13146895 0,14051049 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,13341353 0,14252258 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,13341353 0,14245642 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,13341353 0,14239031 ! hexose catabolic process GO:0019320 82 64 0,000 0,13341353 0,14232427 ! adaptive immune response GO:0002250 94 64 0,000 0,13341353 0,14225828 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,13535387 0,14426038 ! B cell activation GO:0042113 104 65 0,000 0,13535387 0,14419356 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,13535387 0,14412681 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,13535387 0,14406011 ! defense response to bacterium GO:0042742 73 65 0,000 0,13535387 0,14399348 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,13535387 0,14392691 ! activation of immune response GO:0002253 83 65 0,000 0,13535387 0,1438604 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,13728998 0,14585079 ! cell-substrate adhesion GO:0031589 121 66 0,000 0,13728998 0,14578345 ! antigen processing and presentation GO:0019882 96 66 0,000 0,13728998 0,14571618 ! axon guidance GO:0007411 99 66 0,000 0,13728998 0,14564896 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,13728998 0,14558181 ! regulation of immune effector process GO:0002697 101 66 0,000 0,13728998 0,14551473 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,13922186 0,14749437 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,13922186 0,14742647 ! acute inflammatory response GO:0002526 92 68 0,000 0,14114953 0,14939895 ! learning or memory GO:0007611 123 68 0,000 0,14114953 0,14933023 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,14114953 0,14926157 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,14114953 0,14919298 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,14114953 0,14912445 ! rhythmic process GO:0048511 105 68 0,000 0,14114953 0,14905598 ! inorganic anion transport GO:0015698 93 68 0,000 0,14114953 0,14898757 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,14307299 0,15094857 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,14307299 0,15087936 ! response to drug GO:0042493 108 69 0,000 0,14307299 0,15081021 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,14307299 0,15074113 ! response to metal ion GO:0010038 103 70 0,000 0,14499226 0,15269331 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,14499226 0,15262343 ! humoral immune response GO:0006959 86 70 0,000 0,14499226 0,15255361 ! amine transport GO:0015837 101 70 0,000 0,14499226 0,15248386 ! regulation of catabolic process GO:0009894 106 70 0,000 0,14499226 0,15241417 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,14690733 0,15435672 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,14690733 0,15428624 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,14690733 0,15421582 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,14690733 0,15414547 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,14690733 0,15407518 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,14690733 0,15400495 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,14881823 0,1559371 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,14881823 0,15586609 ! negative regulation of transport GO:0051051 116 73 0,000 0,15072496 0,15779126 ! regulation of blood pressure GO:0008217 107 73 0,000 0,15072496 0,15771947 ! tube morphogenesis GO:0035239 118 73 0,000 0,15072496 0,15764775 ! mitochondrion organization GO:0007005 104 73 0,000 0,15072496 0,15757609 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,15072496 0,1575045 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,15072496 0,15743297 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,15262752 0,15934784 ! digestion GO:0007586 97 74 0,000 0,15262752 0,15927554 ! protein import into nucleus GO:0006606 118 74 0,000 0,15262752 0,15920331 ! blood coagulation GO:0007596 116 75 0,000 0,15452593 0,16111044 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,15452593 0,16103744 ! response to nutrient GO:0007584 104 75 0,000 0,15452593 0,16096451 ! regulation of ligase activity GO:0051340 114 75 0,000 0,15452593 0,16089164 ! nuclear import GO:0051170 121 75 0,000 0,15452593 0,16081884 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,15452593 0,16074611 ! amine biosynthetic process GO:0009309 97 76 0,000 0,1564202 0,16264306 ! tRNA metabolic process GO:0006399 95 76 0,000 0,1564202 0,16256957 ! response to unfolded protein GO:0006986 99 76 0,000 0,1564202 0,16249614 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,1564202 0,16242278 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,15831033 0,16431126 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,15831033 0,16423715 ! regulation of DNA binding GO:0051101 119 77 0,000 0,15831033 0,1641631 ! sex differentiation GO:0007548 105 77 0,000 0,15831033 0,16408912 ! protein ubiquitination GO:0016567 125 77 0,000 0,15831033 0,1640152 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,15831033 0,16394136 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,15831033 0,16386757 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,15831033 0,16379386 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,16019633 0,16567067 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,16019633 0,16559621 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,16019633 0,16552181 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,16207822 0,16739106 ! cellular respiration GO:0045333 107 79 0,000 0,16207822 0,16731593 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,16207822 0,16724087 ! T cell activation GO:0042110 134 79 0,000 0,16207822 0,16716587 ! regulation of lyase activity GO:0051339 133 79 0,000 0,16207822 0,16709094 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,16207822 0,16701608 ! chromatin assembly GO:0031497 102 80 0,000 0,16395599 0,16887541 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,16395599 0,16879981 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,16395599 0,16872429 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,16395599 0,16864883 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,16395599 0,16857344 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,16582967 0,1704237 ! hemostasis GO:0007599 125 81 0,000 0,16582967 0,17034758 ! mRNA transport GO:0051028 121 81 0,000 0,16582967 0,17027154 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,16582967 0,17019556 ! response to protein stimulus GO:0051789 111 81 0,000 0,16582967 0,17011964 ! regulation of neurological system process GO:0031644 122 81 0,000 0,16582967 0,1700438 ! vitamin metabolic process GO:0006766 103 81 0,000 0,16582967 0,16996802 ! detection of stimulus GO:0051606 108 82 0,000 0,16769925 0,1718077 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,16956476 0,17364156 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,16956476 0,17356428 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,16956476 0,17348707 ! regulation of defense response GO:0031347 117 84 0,000 0,17142618 0,17531357 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,17142618 0,17523565 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,17142618 0,17515781 ! sterol metabolic process GO:0016125 120 84 0,000 0,17142618 0,17508003 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,17328355 0,17689843 ! rRNA metabolic process GO:0016072 107 85 0,000 0,17328355 0,17681994 GO:0006364|rRNA processing, ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,17328355 0,17674153 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,17513685 0,17855264 ! nucleosome organization GO:0034728 114 87 0,000 0,17698611 0,18035802 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,17698611 0,18027814 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,17698611 0,18019834 ! female pregnancy GO:0007565 130 87 0,000 0,17698611 0,1801186 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,17883132 0,18191598 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,17883132 0,18183556 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,17883132 0,18175521 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,17883132 0,18167493 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,18067251 0,18346436 ! reproductive developmental process GO:0003006 127 89 0,000 0,18067251 0,18338339 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,18067251 0,1833025 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,18067251 0,18322168 ! regulation of T cell activation GO:0050863 128 89 0,000 0,18067251 0,18314093 ! leukocyte differentiation GO:0002521 143 90 0,000 0,18250967 0,18492169 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,18250967 0,18484027 ! hormone metabolic process GO:0042445 121 90 0,000 0,18250967 0,18475891 ! RNA localization GO:0006403 135 91 0,000 0,18434282 0,18653255 ! ATP metabolic process GO:0046034 137 91 0,000 0,18434282 0,18645052 ! response to virus GO:0009615 122 91 0,000 0,18434282 0,18636856 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,18617196 0,18813511 ! positive regulation of immune response GO:0050778 121 92 0,000 0,18617196 0,18805249 ! DNA recombination GO:0006310 146 92 0,000 0,18617196 0,18796994 ! sulfur metabolic process GO:0006790 118 92 0,000 0,18617196 0,18788746 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,18799711 0,18964621 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,18799711 0,18956306 ! electron transport chain GO:0022900 123 94 0,000 0,18981827 0,19131552 ! response to oxidative stress GO:0006979 141 94 0,000 0,18981827 0,19123172 ! regulation of binding GO:0051098 151 95 0,000 0,19163544 0,1929779 ! angiogenesis GO:0001525 149 95 0,000 0,19163544 0,19289345 ! carboxylic acid transport GO:0046942 147 95 0,000 0,19163544 0,19280906 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,19344865 0,19454827 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,19344865 0,19446324 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,19344865 0,19437829 ! protein maturation GO:0051604 129 96 0,000 0,19344865 0,1942934 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,19525789 0,19602495 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,19525789 0,19593942 ! extracellular structure organization GO:0043062 156 99 0,000 0,19886453 0,19947161 ! protein import GO:0017038 156 99 0,000 0,19886453 0,19938466 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,19886453 0,19929778 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,20066193 0,20101151 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,20066193 0,200924 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,20066193 0,20083657 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,20066193 0,20074921 ! protein localization in organelle GO:0033365 161 100 0,000 0,20066193 0,20066193