pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/611-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 1,454E-11 3,553E-08 ! auditory receptor cell differentiation GO:0042491 36 17 4,000 1,929E-10 2,357E-07 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 4,000 8,145E-10 6,633E-07 ! inner ear receptor cell differentiation GO:0060113 42 22 4,000 8,145E-10 4,975E-07 ! mechanoreceptor differentiation GO:0042490 48 24 4,000 1,31E-09 6,403E-07 ! androgen receptor signaling pathway GO:0030521 81 37 4,000 1,316E-08 5,36E-06 ! inner ear development GO:0048839 89 53 4,000 8,448E-08 2,948E-05 ! myoblast cell fate commitment GO:0048625 18 6 2,000 1,655E-07 5,053E-05 ! ear development GO:0043583 114 66 4,000 2,577E-07 6,995E-05 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 2,577E-07 6,295E-05 ! lung development GO:0030324 165 69 4,000 3,225E-07 7,163E-05 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 3,724E-07 7,582E-05 ! respiratory tube development GO:0030323 171 72 4,000 3,996E-07 7,509E-05 ! respiratory system development GO:0060541 175 74 4,000 4,586E-07 8,003E-05 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 4,62E-07 7,524E-05 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 1,355E-06 2,069E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 1,804E-06 2,593E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 2,502E-06 3,396E-04 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 3,715E-06 4,777E-04 ! myoblast differentiation GO:0045445 50 17 2,000 5,536E-06 6,762E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 5,955E-06 6,928E-04 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 7,865E-06 8,734E-04 ! pancreas development GO:0031016 40 20 2,000 9,24E-06 9,814E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,076E-05 1,096E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,279E-05 1,25E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,355E-05 1,273E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,69E-05 1,529E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 1,85E-05 1,614E-03 ! muscle cell differentiation GO:0042692 178 81 3,000 2,417E-05 2,036E-03 ! fat cell differentiation GO:0045444 57 28 2,000 2,624E-05 2,137E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 2,922E-05 2,303E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 4,144E-05 3,164E-03 ! positive regulation of vasoconstriction GO:0045907 10 5 1,000 4,144E-05 3,068E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 4,144E-05 2,977E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 5,111E-05 3,567E-03 ! skeletal muscle tissue development GO:0007519 223 100 3,000 5,531E-05 3,753E-03 GO:0060538|skeletal muscle organ development, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 6,207E-05 4,099E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 6,207E-05 3,991E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 7,202E-05 4,512E-03 GO:0042593|glucose homeostasis, ! regulation of hormone secretion GO:0046883 69 41 2,000 8,376E-05 5,116E-03 ! mesenchymal cell development GO:0014031 94 41 2,000 8,376E-05 4,991E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 1,000 8,679E-05 5,048E-03 ! vesicle fusion GO:0006906 20 7 1,000 8,679E-05 4,931E-03 ! positive regulation of microtubule polymerization GO:0031116 15 7 1,000 8,679E-05 4,819E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,156E-04 6,274E-03 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 1,156E-04 6,137E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,156E-04 6,007E-03 ! gas homeostasis GO:0033483 14 8 1,000 1,156E-04 5,882E-03 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 1,000 1,156E-04 5,762E-03 ! regulation of microtubule polymerization GO:0031113 17 8 1,000 1,156E-04 5,646E-03 ! protein homooligomerization GO:0051260 84 49 2,000 1,431E-04 6,853E-03 ! regulation of epithelial cell differentiation GO:0030856 18 9 1,000 1,484E-04 6,971E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,484E-04 6,84E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,484E-04 6,713E-03 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,484E-04 6,591E-03 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 2,000 1,709E-04 7,454E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,852E-04 7,939E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,852E-04 7,802E-03 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 1,852E-04 7,67E-03 ! response to UV GO:0009411 120 55 2,000 2,019E-04 8,222E-03 ! skeletal muscle fiber development GO:0048741 130 56 2,000 2,131E-04 8,533E-03 ! RNA elongation GO:0006354 90 56 2,000 2,131E-04 8,395E-03 ! muscle fiber development GO:0048747 131 57 2,000 2,246E-04 8,708E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 2,261E-04 8,63E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 2,71E-04 0,01018369 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,71E-04 0,01002939 ! localization within membrane GO:0051668 26 12 1,000 2,71E-04 9,88E-03 ! positive regulation of secretion GO:0051047 110 61 2,000 2,746E-04 9,865E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 3,165E-04 0,01120509 ! organelle fusion GO:0048284 36 13 1,000 3,198E-04 0,01116075 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 3,198E-04 0,01100355 ! gland morphogenesis GO:0022612 31 13 1,000 3,198E-04 0,01085073 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 3,466E-04 0,01159815 ! negative regulation of cell growth GO:0030308 142 67 2,000 3,623E-04 0,01196013 ! lipid localization GO:0010876 32 14 1,000 3,726E-04 0,01213666 GO:0019915|lipid storage, ! positive regulation of protein polymerization GO:0032273 27 14 1,000 3,726E-04 0,01197696 ! negative regulation of cell size GO:0045792 144 69 2,000 3,951E-04 0,0125343 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 4,293E-04 0,01344732 ! regulation of vasodilation GO:0042312 27 15 1,000 4,293E-04 0,0132771 ! stem cell development GO:0048864 46 16 1,000 4,9E-04 0,01496424 GO:0019827|stem cell maintenance, ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,9E-04 0,0147795 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 5,546E-04 0,01652384 ! protein oligomerization GO:0051259 149 79 2,000 5,876E-04 0,01729447 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 6,231E-04 0,0181226 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 6,231E-04 0,0179094 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 6,321E-04 0,01795562 ! regulation of peptidase activity GO:0052547 150 82 2,000 6,551E-04 0,0183962 ! intracellular protein transmembrane transport GO:0065002 165 83 2,000 6,787E-04 0,01884147 ! negative regulation of growth GO:0045926 168 85 2,000 7,274E-04 0,01996783 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 7,718E-04 0,02094907 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,718E-04 0,02071886 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,718E-04 0,02049366 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 7,718E-04 0,02027329 ! lipid phosphorylation GO:0046834 43 21 1,000 8,519E-04 0,0221395 ! regulation of vasoconstriction GO:0019229 40 21 1,000 8,519E-04 0,02190646 ! inactivation of MAPK activity GO:0000188 45 22 1,000 9,358E-04 0,02381442 ! stem cell differentiation GO:0048863 57 22 1,000 9,358E-04 0,02356891 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 9,358E-04 0,02332841 ! G1 phase GO:0051318 44 22 1,000 9,358E-04 0,02309277 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 9,358E-04 0,02286184 ! positive regulation of B cell activation GO:0050871 42 22 1,000 9,358E-04 0,02263549 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 1,024E-03 0,0245156 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 1,024E-03 0,02427759 ! transcription initiation GO:0006352 171 97 2,000 1,067E-03 0,02506261 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 1,115E-03 0,02594568 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 1,115E-03 0,02570091 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,115E-03 0,02546071 ! membrane depolarization GO:0051899 45 24 1,000 1,115E-03 0,02522496 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 1,115E-03 0,02499354 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 1,115E-03 0,02476633 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,211E-03 0,02664199 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,211E-03 0,02640411 ! vasculogenesis GO:0001570 49 25 1,000 1,211E-03 0,02617045 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,31E-03 0,02806532 ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 1,31E-03 0,02782128 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,31E-03 0,02758144 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 1,31E-03 0,0273457 ! regulation of blood coagulation GO:0030193 46 26 1,000 1,31E-03 0,02711396 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,413E-03 0,02899846 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 1,413E-03 0,02875681 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 1,519E-03 0,03067218 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 1,519E-03 0,03042077 ! vesicle docking GO:0048278 55 28 1,000 1,519E-03 0,03017344 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 1,744E-03 0,03435205 ! cell fate determination GO:0001709 64 30 1,000 1,744E-03 0,03407724 ! regulation of B cell activation GO:0050864 55 30 1,000 1,744E-03 0,03380678 ! regulation of coagulation GO:0050818 52 30 1,000 1,744E-03 0,03354059 ! erythrocyte differentiation GO:0030218 62 31 1,000 1,861E-03 0,03552644 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 1,861E-03 0,03525104 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 1,861E-03 0,03497988 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,983E-03 0,03697795 ! mesoderm formation GO:0001707 73 32 1,000 1,983E-03 0,03669781 ! cholesterol homeostasis GO:0042632 60 33 1,000 2,108E-03 0,03872028 GO:0055092|sterol homeostasis, ! triglyceride metabolic process GO:0006641 46 33 1,000 2,108E-03 0,03843133 ! post-embryonic development GO:0009791 76 34 1,000 2,237E-03 0,04047708 ! cholesterol transport GO:0030301 62 34 1,000 2,237E-03 0,04017946 ! formation of primary germ layer GO:0001704 76 34 1,000 2,237E-03 0,03988618 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,237E-03 0,03959715 ! membrane docking GO:0022406 69 35 1,000 2,369E-03 0,04163957 ! mesoderm morphogenesis GO:0048332 80 35 1,000 2,369E-03 0,04134214 ! sterol transport GO:0015918 63 35 1,000 2,369E-03 0,04104894 ! calcium-mediated signaling GO:0019722 67 35 1,000 2,369E-03 0,04075986 ! tissue remodeling GO:0048771 78 37 1,000 2,645E-03 0,0451846 ! regulation of microtubule-based process GO:0032886 86 37 1,000 2,645E-03 0,04487082 ! neutral lipid metabolic process GO:0006638 54 38 1,000 2,788E-03 0,04697467 GO:0006639|acylglycerol metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 2,788E-03 0,04665293 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 2,788E-03 0,04633556 ! erythrocyte homeostasis GO:0034101 75 39 1,000 2,935E-03 0,04844592 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 2,935E-03 0,04812078 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 3,085E-03 0,05024912 ! lipid homeostasis GO:0055088 75 40 1,000 3,085E-03 0,04991634 ! glycerol ether metabolic process GO:0006662 57 40 1,000 3,085E-03 0,04958795 ! organic ether metabolic process GO:0018904 59 42 1,000 3,397E-03 0,05423578 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 3,397E-03 0,0538836 ! striated muscle cell differentiation GO:0051146 91 43 1,000 3,558E-03 0,05607313 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 3,558E-03 0,05571369 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 3,89E-03 0,06053184 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 3,89E-03 0,06014872 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 4,062E-03 0,06240458 ! positive regulation of protein transport GO:0051222 80 46 1,000 4,062E-03 0,06201455 ! response to insulin stimulus GO:0032868 98 47 1,000 4,236E-03 0,06428328 ! positive regulation of cell cycle GO:0045787 96 48 1,000 4,415E-03 0,06657595 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 4,415E-03 0,06616751 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 4,597E-03 0,06847182 ! epidermal cell differentiation GO:0009913 87 50 1,000 4,782E-03 0,07079878 ! vesicle organization GO:0016050 127 53 1,000 5,358E-03 0,07884806 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 5,358E-03 0,07837592 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! activation of phospholipase C activity GO:0007202 110 54 1,000 5,556E-03 0,08079897 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 1,000 5,556E-03 0,08032087 ! membrane fusion GO:0006944 122 54 1,000 5,556E-03 0,0798484 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 5,758E-03 0,08226811 ! regulation of protein polymerization GO:0032271 117 55 1,000 5,758E-03 0,0817898 ! regulation of phospholipase activity GO:0010517 113 57 1,000 6,173E-03 0,08716448 ! nucleotide-excision repair GO:0006289 91 57 1,000 6,173E-03 0,08666353 ! regulation of intracellular transport GO:0032386 108 57 1,000 6,173E-03 0,08616831 ! positive regulation of cell migration GO:0030335 137 58 1,000 6,385E-03 0,08862145 ! gastrulation GO:0007369 122 58 1,000 6,385E-03 0,08812077 ! positive regulation of organelle organization GO:0010638 108 58 1,000 6,385E-03 0,08762571 ! positive regulation of lipase activity GO:0060193 115 58 1,000 6,385E-03 0,08713618 ! lipid modification GO:0030258 112 60 1,000 6,818E-03 0,09254044 ! DNA catabolic process GO:0006308 94 60 1,000 6,818E-03 0,09202917 ! camera-type eye development GO:0043010 126 61 1,000 7,04E-03 0,09450106 ! regulation of protein complex assembly GO:0043254 132 63 1,000 7,494E-03 0,10003703 ! mesoderm development GO:0007498 128 63 1,000 7,494E-03 0,09949335 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 7,725E-03 0,10201285 ! positive regulation of cell motion GO:0051272 157 65 1,000 7,96E-03 0,10454734 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 8,439E-03 0,11024606 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 126 67 1,000 8,439E-03 0,10965964 ! regulation of lipase activity GO:0060191 137 68 1,000 8,683E-03 0,11223663 ! homeostasis of number of cells GO:0048872 131 69 1,000 8,93E-03 0,114827 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 8,93E-03 0,11422581 ! cell cycle checkpoint GO:0000075 145 71 1,000 9,435E-03 0,1200463 ! appendage morphogenesis GO:0035107 150 72 1,000 9,691E-03 0,1226745 GO:0035108|limb morphogenesis, ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 9,691E-03 0,12204216 ! appendage development GO:0048736 151 73 1,000 9,951E-03 0,12467194 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 1,000 0,01021425 0,12731331 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01022744 0,12683066 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01022744 0,1261901 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01022744 0,12555598 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01022744 0,1249282 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01022744 0,12430666 ! neuron fate determination GO:0048664 7 5 0,000 0,01022744 0,12369128 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01022744 0,12308197 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01022744 0,12247862 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01022744 0,12188117 ! polyol transport GO:0015791 12 5 0,000 0,01022744 0,12128951 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01022744 0,12070357 ! response to superoxide GO:0000303 10 5 0,000 0,01022744 0,12012327 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01022744 0,11954851 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01022744 0,11897924 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01022744 0,11841535 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01022744 0,11785679 ! female meiosis GO:0007143 10 5 0,000 0,01022744 0,11730347 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01022744 0,11675532 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01022744 0,11621228 ! hypothalamus development GO:0021854 9 5 0,000 0,01022744 0,11567426 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01022744 0,1151412 ! cobalt ion transport GO:0006824 11 5 0,000 0,01022744 0,11461303 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01022744 0,11408968 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01022744 0,11357109 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01022744 0,11305719 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01022744 0,11254793 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01022744 0,11204323 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01022744 0,11154303 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01022744 0,11104729 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01022744 0,11055593 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01022744 0,1100689 ! transposition GO:0032196 9 5 0,000 0,01022744 0,10958614 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01022744 0,1091076 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01022744 0,10863322 ! negative chemotaxis GO:0050919 16 5 0,000 0,01022744 0,10816294 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01022744 0,10769672 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01022744 0,1072345 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01022744 0,10677624 ! behavioral response to pain GO:0048266 10 5 0,000 0,01022744 0,10632187 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01022744 0,10587135 ! Notch receptor processing GO:0007220 11 5 0,000 0,01022744 0,10542464 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01022744 0,10498168 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01022744 0,10454242 ! micturition GO:0060073 9 5 0,000 0,01022744 0,10410683 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01022744 0,10367485 ! copulation GO:0007620 9 5 0,000 0,01022744 0,10324644 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01022744 0,10282156 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01022744 0,10240016 ! bioluminescence GO:0008218 9 5 0,000 0,01022744 0,1019822 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01022744 0,10156764 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01022744 0,10115644 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01022744 0,10074855 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01022744 0,10034393 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01022744 0,09994256 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01022744 0,09954438 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01022744 0,09914936 ! grooming behavior GO:0007625 6 5 0,000 0,01022744 0,09875747 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01022744 0,09836866 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01022744 0,0979829 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01022744 0,09760015 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01022744 0,09722039 ! response to protozoan GO:0001562 13 5 0,000 0,01022744 0,09684356 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01022744 0,09646965 ! lymph vessel development GO:0001945 10 5 0,000 0,01022744 0,09609861 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01022744 0,09573042 ! endochondral ossification GO:0001958 17 5 0,000 0,01022744 0,09536504 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01022744 0,09500243 ! single strand break repair GO:0000012 8 5 0,000 0,01022744 0,09464257 ! parathyroid gland development GO:0060017 14 5 0,000 0,01022744 0,09428543 ! anagen GO:0042640 7 5 0,000 0,01022744 0,09393098 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01022744 0,09357917 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01022744 0,09323 ! cytokine secretion GO:0050663 15 5 0,000 0,01022744 0,09288342 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01022744 0,09253941 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01022744 0,09219793 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01022744 0,09185897 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01022744 0,09152249 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01022744 0,09118847 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01022744 0,09085687 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01022744 0,09052768 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01022744 0,09020086 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01022744 0,0898764 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01022744 0,08955426 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01022744 0,08923443 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01022744 0,08891687 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01022744 0,08860156 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01022744 0,08828848 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01022744 0,0879776 ! microvillus organization GO:0032528 8 5 0,000 0,01022744 0,08766891 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01022744 0,08736238 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01022744 0,08705798 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01022744 0,08675569 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01022744 0,0864555 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01022744 0,08615738 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01022744 0,0858613 ! polyol catabolic process GO:0046174 9 5 0,000 0,01022744 0,08556726 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01022744 0,08527522 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01022744 0,08498517 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01022744 0,08469708 ! muscle cell migration GO:0014812 8 5 0,000 0,01022744 0,08441094 ! mitochondrial fission GO:0000266 8 5 0,000 0,01022744 0,08412673 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01022744 0,08384443 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01022744 0,08356401 ! mRNA transcription GO:0009299 10 5 0,000 0,01022744 0,08328546 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01022744 0,08300877 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01022744 0,08273391 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01022744 0,08246086 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01022744 0,0821896 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01022744 0,08192013 ! monocyte activation GO:0042117 10 5 0,000 0,01022744 0,08165242 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01022744 0,08138645 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01022744 0,08112221 ! response to food GO:0032094 6 5 0,000 0,01022744 0,08085967 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01022744 0,08059884 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01022744 0,08033968 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01022744 0,08008218 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01022744 0,07982632 ! forebrain neuron development GO:0021884 13 5 0,000 0,01022744 0,0795721 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01022744 0,07931949 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01022744 0,07906848 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01022744 0,07881905 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01022744 0,07857119 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01022744 0,07832489 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01022744 0,07808012 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01022744 0,07783688 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01022744 0,07759515 ! lipid glycosylation GO:0030259 7 5 0,000 0,01022744 0,07735492 ! nucleobase transport GO:0015851 6 5 0,000 0,01022744 0,07711617 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01022744 0,07687889 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01022744 0,07664307 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01022744 0,07640868 ! basic amino acid transport GO:0015802 12 5 0,000 0,01022744 0,07617573 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01022744 0,07594419 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01022744 0,07571406 ! actin nucleation GO:0045010 11 5 0,000 0,01022744 0,07548532 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01022744 0,07525795 ! depurination GO:0045007 5 5 0,000 0,01022744 0,07503195 ! depyrimidination GO:0045008 10 5 0,000 0,01022744 0,0748073 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01022744 0,074584 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01022744 0,07436202 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01022744 0,07414136 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01022744 0,07392201 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01022744 0,07370395 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01022744 0,07348717 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01022744 0,07327167 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01022744 0,07305743 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01022744 0,07284443 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01022744 0,07263267 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01022744 0,07242214 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01022744 0,07221283 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01022744 0,07200472 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01022744 0,07179781 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01022744 0,07159209 ! response to arsenic GO:0046685 11 5 0,000 0,01022744 0,07138754 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01022744 0,07118416 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01022744 0,07098193 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01022744 0,07078085 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01022744 0,0705809 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01022744 0,07038208 ! response to mercury ion GO:0046689 8 5 0,000 0,01022744 0,07018438 ! response to cadmium ion GO:0046686 7 5 0,000 0,01022744 0,06998779 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01022744 0,06979229 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01022744 0,06959788 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01022744 0,06940455 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01022744 0,0692123 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01022744 0,0690211 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01022744 0,06883096 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01022744 0,06864187 ! decidualization GO:0046697 11 5 0,000 0,01022744 0,06845381 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01022744 0,06826677 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01022744 0,06808076 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01022744 0,06789576 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01022744 0,06771176 ! embryonic cleavage GO:0040016 6 5 0,000 0,01022744 0,06752876 ! peroxisome fission GO:0016559 5 5 0,000 0,01022744 0,06734674 ! histone demethylation GO:0016577 13 5 0,000 0,01022744 0,0671657 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01022744 0,06698563 ! mitotic recombination GO:0006312 9 5 0,000 0,01022744 0,06680652 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01022744 0,06662837 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01022744 0,06645117 ! metaphase plate congression GO:0051310 7 5 0,000 0,01022744 0,06627491 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01022744 0,06609958 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01022744 0,06592517 ! enteric nervous system development GO:0048484 8 5 0,000 0,01022744 0,06575168 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01022744 0,06557911 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01022744 0,06540743 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01022744 0,06523666 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01022744 0,06506677 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01022744 0,06489776 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01022744 0,06472964 ! B cell homeostasis GO:0001782 13 5 0,000 0,01022744 0,06456238 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01022744 0,06439598 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01022744 0,06423044 ! metaphase GO:0051323 11 5 0,000 0,01022744 0,06406574 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01022744 0,06390189 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01022744 0,06373888 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01022744 0,06357669 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01022744 0,06341533 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01022744 0,06325478 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01022744 0,06309505 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01022744 0,06293612 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01022744 0,06277799 ! response to redox state GO:0051775 6 5 0,000 0,01022744 0,06262065 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01022744 0,0624641 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01022744 0,06230833 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01022744 0,06215333 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01022744 0,06199911 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01022744 0,06184564 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01022744 0,06169294 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01022744 0,06154098 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01022744 0,06138978 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01022744 0,06123931 ! striatum development GO:0021756 14 5 0,000 0,01022744 0,06108958 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01022744 0,06094058 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01022744 0,06079231 ! glial cell migration GO:0008347 10 5 0,000 0,01022744 0,06064476 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01022744 0,06049792 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01022744 0,06035179 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01022744 0,06020636 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01022744 0,06006163 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01022744 0,0599176 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01022744 0,05977426 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01022744 0,0596316 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01022744 0,05948962 ! neuroprotection GO:0043526 8 5 0,000 0,01022744 0,05934831 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01022744 0,05920768 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01022744 0,05906771 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01022744 0,05892839 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01022744 0,05878974 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01022744 0,05865174 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01022744 0,05851438 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01022744 0,05837766 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01022744 0,05824158 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01022744 0,05810614 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01022744 0,05797132 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01022744 0,05783713 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01022744 0,05770356 ! spindle assembly GO:0051225 6 5 0,000 0,01022744 0,0575706 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01022744 0,05743825 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01022744 0,05730651 ! protein palmitoylation GO:0018345 12 5 0,000 0,01022744 0,05717538 ! drug metabolic process GO:0017144 7 5 0,000 0,01022744 0,05704484 ! stem cell division GO:0017145 11 5 0,000 0,01022744 0,0569149 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01022744 0,05678554 ! organ regeneration GO:0031100 7 5 0,000 0,01022744 0,05665678 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01022744 0,0565286 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01022744 0,05640099 ! eye development GO:0001654 155 75 1,000 0,01048026 0,05766506 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01102145 0,0605065 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01102145 0,06037084 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01129659 0,06173952 ! response to hypoxia GO:0001666 178 81 1,000 0,01214005 0,06620121 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,01214005 0,06605377 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01226051 0,06656097 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01226051 0,06641339 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01226051 0,06626646 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01226051 0,06612017 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01226051 0,06597453 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01226051 0,06582953 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01226051 0,06568517 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01226051 0,06554144 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01226051 0,06539834 ! response to oxygen radical GO:0000305 11 6 0,000 0,01226051 0,06525586 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01226051 0,065114 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01226051 0,06497275 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01226051 0,06483212 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01226051 0,06469209 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01226051 0,06455267 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01226051 0,06441384 ! forebrain regionalization GO:0021871 9 6 0,000 0,01226051 0,06427562 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01226051 0,06413798 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01226051 0,06400094 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01226051 0,06386447 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01226051 0,06372859 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01226051 0,06359329 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01226051 0,06345855 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01226051 0,06332439 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01226051 0,0631908 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01226051 0,06305776 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01226051 0,06292529 ! malate metabolic process GO:0006108 13 6 0,000 0,01226051 0,06279337 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01226051 0,062662 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01226051 0,06253119 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01226051 0,06240091 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01226051 0,06227118 ! protein refolding GO:0042026 15 6 0,000 0,01226051 0,06214199 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01226051 0,06201333 ! opsonization GO:0008228 8 6 0,000 0,01226051 0,0618852 ! mating behavior GO:0007617 7 6 0,000 0,01226051 0,0617576 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01226051 0,06163053 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01226051 0,06150398 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01226051 0,06137795 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01226051 0,06125243 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01226051 0,06112742 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01226051 0,06100293 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01226051 0,06087894 ! toxin metabolic process GO:0009404 11 6 0,000 0,01226051 0,06075545 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01226051 0,06063247 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01226051 0,06050998 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01226051 0,06038798 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01226051 0,06026647 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01226051 0,06014546 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01226051 0,06002493 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01226051 0,05990488 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01226051 0,05978531 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01226051 0,05966621 ! thymic T cell selection GO:0045061 16 6 0,000 0,01226051 0,05954759 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01226051 0,05942944 ! protein lipoylation GO:0009249 10 6 0,000 0,01226051 0,05931176 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01226051 0,05919454 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01226051 0,05907779 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01226051 0,05896149 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01226051 0,05884565 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01226051 0,05873027 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01226051 0,05861534 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01226051 0,05850086 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01226051 0,05838682 ! hyperosmotic response GO:0006972 10 6 0,000 0,01226051 0,05827323 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01226051 0,05816007 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01226051 0,05804736 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01226051 0,05793508 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01226051 0,05782324 ! urea metabolic process GO:0019627 7 6 0,000 0,01226051 0,05771183 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01226051 0,05760084 ! neutrophil activation GO:0042119 7 6 0,000 0,01226051 0,05749028 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01226051 0,05738015 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01226051 0,05727044 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01226051 0,05716114 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01226051 0,05705226 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01226051 0,0569438 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01226051 0,05683575 ! neuron apoptosis GO:0051402 15 6 0,000 0,01226051 0,0567281 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01226051 0,05662087 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01226051 0,05651403 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01226051 0,0564076 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01226051 0,05630157 ! carnitine transport GO:0015879 10 6 0,000 0,01226051 0,05619594 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01226051 0,05609071 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01226051 0,05598587 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01226051 0,05588141 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01226051 0,05577735 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01226051 0,05567368 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01226051 0,05557039 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01226051 0,05546748 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01226051 0,05536495 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01226051 0,0552628 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01226051 0,05516103 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01226051 0,05505963 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01226051 0,0549586 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01226051 0,05485794 ! response to UV-C GO:0010225 14 6 0,000 0,01226051 0,05475766 ! astrocyte development GO:0014002 16 6 0,000 0,01226051 0,05465773 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01226051 0,05455817 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01226051 0,05445898 ! interaction with symbiont GO:0051702 14 6 0,000 0,01226051 0,05436014 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01226051 0,05426166 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01226051 0,05416354 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01226051 0,05406577 ! response to copper ion GO:0046688 10 6 0,000 0,01226051 0,05396836 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01226051 0,05387129 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01226051 0,05377457 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01226051 0,0536782 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01226051 0,05358218 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01226051 0,0534865 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01226051 0,05339115 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01226051 0,05329615 ! hair follicle maturation GO:0048820 8 6 0,000 0,01226051 0,05320149 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01226051 0,05310716 ! Schwann cell development GO:0014044 15 6 0,000 0,01226051 0,05301316 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01226051 0,0529195 ! response to pheromone GO:0019236 6 6 0,000 0,01226051 0,05282617 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01226051 0,05273317 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01226051 0,05264049 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01226051 0,05254814 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01226051 0,05245611 ! subpallium development GO:0021544 15 6 0,000 0,01226051 0,0523644 ! neural tube patterning GO:0021532 8 6 0,000 0,01226051 0,05227302 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01226051 0,05218195 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01226051 0,0520912 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01226051 0,05200076 ! G2 phase GO:0051319 16 6 0,000 0,01226051 0,05191064 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01226051 0,05182083 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01226051 0,05173133 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01226051 0,05164213 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01226051 0,05155325 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01226051 0,05146467 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01226051 0,05137639 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01226051 0,05128842 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01226051 0,05120075 ! receptor internalization GO:0031623 11 6 0,000 0,01226051 0,05111338 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01226051 0,0510263 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01226051 0,05093952 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01226051 0,05085304 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01226051 0,05076684 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01226051 0,05068094 ! protein deubiquitination GO:0016579 16 6 0,000 0,01226051 0,05059533 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01226051 0,05051001 ! protein destabilization GO:0031648 9 6 0,000 0,01226051 0,05042498 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01226051 0,05034023 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01226051 0,05025577 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01226051 0,05017159 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01226051 0,05008769 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01226051 0,05000407 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01226051 0,04992073 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01226051 0,04983767 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01226051 0,04975488 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01226051 0,04967237 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01226051 0,04959013 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01226051 0,04950816 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01226051 0,04942647 ! neural plate development GO:0001840 9 6 0,000 0,01226051 0,04934504 ! catecholamine transport GO:0051937 9 6 0,000 0,01226051 0,04926388 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01226051 0,04918299 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01226051 0,04910236 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01226051 0,04902199 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01226051 0,04894189 ! maternal placenta development GO:0001893 12 6 0,000 0,01226051 0,04886205 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01226051 0,04878247 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01226051 0,04870315 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01226051 0,04862409 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01226051 0,04854528 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01226051 0,04846673 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01226051 0,04838843 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01226051 0,04831038 GO:0055081|anion homeostasis, ! response to oxygen levels GO:0070482 183 83 1,000 0,01271726 0,05002941 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,01271726 0,04994898 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01330627 0,05217851 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01360516 0,05326508 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,01390697 0,05435956 GO:0070201|regulation of establishment of protein localization, ! tRNA transcription GO:0009304 17 7 0,000 0,01428947 0,05576545 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01428947 0,05567651 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01428947 0,05558786 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01428947 0,05549948 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01428947 0,05541139 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01428947 0,05532357 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01428947 0,05523603 ! sleep GO:0030431 16 7 0,000 0,01428947 0,05514877 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01428947 0,05506179 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01428947 0,05497508 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01428947 0,05488864 ! prostate gland development GO:0030850 14 7 0,000 0,01428947 0,05480247 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01428947 0,05471657 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01428947 0,05463094 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01428947 0,05454558 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01428947 0,05446049 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01428947 0,05437566 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01428947 0,05429109 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01428947 0,05420679 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01428947 0,05412275 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01428947 0,05403897 ! glycolipid transport GO:0046836 11 7 0,000 0,01428947 0,05395545 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01428947 0,05387218 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01428947 0,05378917 ! neuron adhesion GO:0007158 14 7 0,000 0,01428947 0,05370642 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01428947 0,05362392 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01428947 0,05354168 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01428947 0,05345968 ! mRNA stabilization GO:0048255 18 7 0,000 0,01428947 0,05337794 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01428947 0,05329645 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01428947 0,0532152 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01428947 0,05313421 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01428947 0,05305346 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01428947 0,05297295 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01428947 0,05289269 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01428947 0,05281267 ! lipoprotein transport GO:0042953 14 7 0,000 0,01428947 0,05273289 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01428947 0,05265335 ! rhythmic behavior GO:0007622 17 7 0,000 0,01428947 0,05257406 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01428947 0,052495 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01428947 0,05241618 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01428947 0,05233759 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01428947 0,05225924 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01428947 0,05218113 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01428947 0,05210324 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01428947 0,05202559 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01428947 0,05194817 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01428947 0,05187099 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01428947 0,05179403 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01428947 0,05171729 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01428947 0,05164079 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01428947 0,05156451 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01428947 0,05148846 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01428947 0,05141263 ! spinal cord patterning GO:0021511 14 7 0,000 0,01428947 0,05133702 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01428947 0,05126164 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01428947 0,05118647 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01428947 0,05111153 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01428947 0,0510368 ! adrenal gland development GO:0030325 17 7 0,000 0,01428947 0,0509623 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01428947 0,05088801 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01428947 0,05081394 ! ovulation GO:0030728 10 7 0,000 0,01428947 0,05074008 ! adenohypophysis development GO:0021984 11 7 0,000 0,01428947 0,05066643 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01428947 0,05059301 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01428947 0,05051979 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01428947 0,05044678 ! microtubule nucleation GO:0007020 21 7 0,000 0,01428947 0,05037399 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01428947 0,0503014 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01428947 0,05022903 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01428947 0,05015686 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01428947 0,0500849 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01428947 0,05001314 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01428947 0,04994159 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01428947 0,04987025 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01428947 0,04979911 ! galactose metabolic process GO:0006012 13 7 0,000 0,01428947 0,04972817 ! response to dietary excess GO:0002021 8 7 0,000 0,01428947 0,04965743 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01428947 0,04958689 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01428947 0,04951656 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01428947 0,04944642 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01428947 0,04937648 ! organ growth GO:0035265 15 7 0,000 0,01428947 0,04930674 ! nucleoside transport GO:0015858 11 7 0,000 0,01428947 0,0492372 ! nucleoside salvage GO:0043174 11 7 0,000 0,01428947 0,04916785 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01428947 0,0490987 ! male sex determination GO:0030238 15 7 0,000 0,01428947 0,04902974 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01428947 0,04896097 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01428947 0,0488924 ! parturition GO:0007567 16 7 0,000 0,01428947 0,04882402 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01428947 0,04875583 ! rRNA modification GO:0000154 14 7 0,000 0,01428947 0,04868783 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01428947 0,04862002 ! spindle checkpoint GO:0031577 16 7 0,000 0,01428947 0,0485524 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01428947 0,04848496 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01428947 0,04841772 ! monocyte differentiation GO:0030224 16 7 0,000 0,01428947 0,04835066 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01428947 0,04828378 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01428947 0,04821709 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01428947 0,04815058 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01428947 0,04808426 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01428947 0,04801812 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01428947 0,04795216 ! fibrinolysis GO:0042730 11 7 0,000 0,01428947 0,04788638 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01428947 0,04782079 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01428947 0,04775537 ! eating behavior GO:0042755 8 7 0,000 0,01428947 0,04769013 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01428947 0,04762507 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01428947 0,04756018 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01428947 0,04749547 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01428947 0,04743094 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01428947 0,04736659 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01428947 0,0473024 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01428947 0,04723839 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01428947 0,04717456 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01428947 0,0471109 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01428947 0,0470474 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01428947 0,04698408 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01428947 0,04692093 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01428947 0,04685795 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01428947 0,04679514 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01428947 0,04673249 ! histone ubiquitination GO:0016574 9 7 0,000 0,01428947 0,04667002 ! regulation of meiosis GO:0040020 12 7 0,000 0,01428947 0,04660771 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01428947 0,04654556 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01428947 0,04648359 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01428947 0,04642177 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01428947 0,04636012 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01428947 0,04629864 ! transcription termination GO:0006353 14 7 0,000 0,01428947 0,04623732 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01428947 0,04617616 ! anaphase GO:0051322 18 7 0,000 0,01428947 0,04611516 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01428947 0,04605432 ! axonal fasciculation GO:0007413 19 7 0,000 0,01428947 0,04599364 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01428947 0,04593312 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01428947 0,04587276 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01428947 0,04581256 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01428947 0,04575252 ! diuresis GO:0030146 12 7 0,000 0,01428947 0,04569264 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01428947 0,04563291 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01428947 0,04557333 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01428947 0,04551392 ! antibiotic transport GO:0042891 9 7 0,000 0,01428947 0,04545465 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01428947 0,04539554 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01428947 0,04533659 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01428947 0,04527779 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01428947 0,04521914 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01428947 0,04516064 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01428947 0,04510229 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01428947 0,04504409 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01428947 0,04498605 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01428947 0,04492815 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01428947 0,0448704 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01428947 0,0448128 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01428947 0,04475535 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01428947 0,04469805 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01428947 0,04464089 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01428947 0,04458387 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01428947 0,04452701 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01428947 0,04447028 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01428947 0,04441371 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01428947 0,04435727 ! muscle adaptation GO:0043500 13 7 0,000 0,01428947 0,04430098 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01428947 0,04424483 ! retina homeostasis GO:0001895 12 7 0,000 0,01428947 0,04418883 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01428947 0,04413296 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01428947 0,04407724 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01428947 0,04402166 ! ossification GO:0001503 205 91 1,000 0,01514305 0,04659253 ! gland development GO:0048732 220 91 1,000 0,01514305 0,04653393 ! bone development GO:0060348 206 92 1,000 0,01545922 0,04744582 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,01577822 0,04836411 ! regulation of membrane potential GO:0042391 179 94 1,000 0,01610005 0,04928874 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01631431 0,04988219 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01631431 0,04981983 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01631431 0,04975764 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01631431 0,04969559 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01631431 0,04963371 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01631431 0,04957197 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01631431 0,04951039 ! male meiosis GO:0007140 9 8 0,000 0,01631431 0,04944897 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01631431 0,04938769 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01631431 0,04932657 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01631431 0,0492656 ! meiotic prophase I GO:0007128 14 8 0,000 0,01631431 0,04920477 ! response to zinc ion GO:0010043 12 8 0,000 0,01631431 0,0491441 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01631431 0,04908358 ! oligopeptide transport GO:0006857 16 8 0,000 0,01631431 0,04902321 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01631431 0,04896298 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01631431 0,0489029 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01631431 0,04884297 ! signal peptide processing GO:0006465 12 8 0,000 0,01631431 0,04878319 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01631431 0,04872355 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01631431 0,04866406 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01631431 0,04860472 ! succinate metabolic process GO:0006105 17 8 0,000 0,01631431 0,04854551 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01631431 0,04848646 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01631431 0,04842754 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01631431 0,04836877 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01631431 0,04831014 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01631431 0,04825165 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01631431 0,04819331 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01631431 0,0481351 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01631431 0,04807704 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01631431 0,04801912 ! reflex GO:0060004 17 8 0,000 0,01631431 0,04796133 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01631431 0,04790369 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01631431 0,04784618 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01631431 0,04778881 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01631431 0,04773158 ! pigment granule organization GO:0048753 17 8 0,000 0,01631431 0,04767448 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01631431 0,04761752 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01631431 0,0475607 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01631431 0,04750401 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01631431 0,04744746 ! histidine catabolic process GO:0006548 10 8 0,000 0,01631431 0,04739104 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01631431 0,04733476 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01631431 0,04727861 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01631431 0,04722259 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01631431 0,04716671 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01631431 0,04711095 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01631431 0,04705533 ! melanin metabolic process GO:0006582 17 8 0,000 0,01631431 0,04699984 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01631431 0,04694448 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01631431 0,04688925 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01631431 0,04683416 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01631431 0,04677919 ! macrophage activation GO:0042116 13 8 0,000 0,01631431 0,04672435 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01631431 0,04666963 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01631431 0,04661505 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01631431 0,04656059 ! purine salvage GO:0043101 12 8 0,000 0,01631431 0,04650626 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01631431 0,04645206 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01631431 0,04639798 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01631431 0,04634403 ! osteoblast development GO:0002076 17 8 0,000 0,01631431 0,04629021 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01631431 0,0462365 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01631431 0,04618293 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01631431 0,04612948 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01631431 0,04607615 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01631431 0,04602294 ! response to UV-B GO:0010224 17 8 0,000 0,01631431 0,04596986 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01631431 0,0459169 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01631431 0,04586406 ! intermediate filament organization GO:0045109 12 8 0,000 0,01631431 0,04581134 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01631431 0,04575874 ! cellular extravasation GO:0045123 13 8 0,000 0,01631431 0,04570627 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01631431 0,04565391 ! response to antibiotic GO:0046677 11 8 0,000 0,01631431 0,04560168 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01631431 0,04554956 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01631431 0,04549756 ! DNA topological change GO:0006265 12 8 0,000 0,01631431 0,04544569 ! response to tropane GO:0014073 15 8 0,000 0,01631431 0,04539393 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01631431 0,04534228 ! melanosome transport GO:0032402 13 8 0,000 0,01631431 0,04529076 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01631431 0,04523935 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01631431 0,04518806 ! mast cell activation GO:0045576 14 8 0,000 0,01631431 0,04513688 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01631431 0,04508582 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01631431 0,04503488 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01631431 0,04498405 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01631431 0,04493333 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01631431 0,04488273 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01631431 0,04483225 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01631431 0,04478187 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01631431 0,04473161 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01631431 0,04468146 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01631431 0,04463143 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01631431 0,04458151 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01631431 0,04453169 ! response to tumor cell GO:0002347 16 8 0,000 0,01631431 0,04448199 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01631431 0,0444324 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01631431 0,04438292 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01631431 0,04433356 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01631431 0,0442843 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01631431 0,04423515 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01631431 0,0441861 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01631431 0,04413717 ! hormone catabolic process GO:0042447 17 8 0,000 0,01631431 0,04408835 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01631431 0,04403963 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01631431 0,04399102 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01631431 0,04394252 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01631431 0,04389413 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01631431 0,04384584 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01631431 0,04379766 ! adult feeding behavior GO:0008343 10 8 0,000 0,01631431 0,04374958 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01631431 0,04370161 ! ATP catabolic process GO:0006200 11 8 0,000 0,01631431 0,04365374 ! blastocyst growth GO:0001832 19 8 0,000 0,01631431 0,04360598 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01631431 0,04355832 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01631431 0,04351077 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01631431 0,04346332 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01631431 0,04341598 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01631431 0,04336873 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01631431 0,04332159 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01631431 0,04327456 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01631431 0,04322762 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01631431 0,04318079 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01631431 0,04313405 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01631431 0,04308742 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01631431 0,04304089 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01631431 0,04299446 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01631431 0,04294813 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01631431 0,0429019 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01631431 0,04285577 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01631431 0,04280974 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01631431 0,04276381 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,01642468 0,04300696 ! regulation of protein localization GO:0032880 188 97 1,000 0,01708233 0,04468107 ! forebrain development GO:0030900 210 98 1,000 0,01741531 0,04550332 ! axon extension GO:0048675 16 9 0,000 0,01833505 0,04785527 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01833505 0,0478042 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01833505 0,04775324 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01833505 0,04770238 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01833505 0,04765164 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01833505 0,047601 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01833505 0,04755046 ! reproductive behavior GO:0019098 22 9 0,000 0,01833505 0,04750004 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01833505 0,04744972 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01833505 0,04739951 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01833505 0,0473494 ! UTP metabolic process GO:0046051 10 9 0,000 0,01833505 0,04729941 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01833505 0,04724951 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01833505 0,04719972 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,01833505 0,04715004 ! artery development GO:0060840 25 9 0,000 0,01833505 0,04710046 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01833505 0,04705098 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01833505 0,04700161 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01833505 0,04695234 ! equilibrioception GO:0050957 20 9 0,000 0,01833505 0,04690318 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01833505 0,04685412 ! chemosensory behavior GO:0007635 21 9 0,000 0,01833505 0,04680516 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01833505 0,0467563 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01833505 0,04670755 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01833505 0,04665889 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01833505 0,04661034 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01833505 0,04656189 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01833505 0,04651354 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01833505 0,04646529 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01833505 0,04641714 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01833505 0,04636909 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01833505 0,04632113 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01833505 0,04627328 ! protein targeting to ER GO:0045047 25 9 0,000 0,01833505 0,04622553 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01833505 0,04617787 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01833505 0,04613032 ! T cell selection GO:0045058 27 9 0,000 0,01833505 0,04608286 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01833505 0,0460355 ! glycine catabolic process GO:0006546 15 9 0,000 0,01833505 0,04598823 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01833505 0,04594106 ! endosome organization GO:0007032 20 9 0,000 0,01833505 0,04589399 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01833505 0,04584702 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01833505 0,04580014 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01833505 0,04575336 ! mannose metabolic process GO:0006013 13 9 0,000 0,01833505 0,04570667 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01833505 0,04566008 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01833505 0,04561358 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01833505 0,04556718 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01833505 0,04552087 ! receptor clustering GO:0043113 20 9 0,000 0,01833505 0,04547466 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01833505 0,04542854 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01833505 0,04538251 ! retinol metabolic process GO:0042572 20 9 0,000 0,01833505 0,04533658 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01833505 0,04529074 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01833505 0,04524499 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01833505 0,04519933 ! macrophage differentiation GO:0030225 15 9 0,000 0,01833505 0,04515377 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01833505 0,0451083 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01833505 0,04506291 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01833505 0,04501763 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01833505 0,04497243 ! response to amine stimulus GO:0014075 13 9 0,000 0,01833505 0,04492732 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01833505 0,0448823 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01833505 0,04483737 ! erythrocyte development GO:0048821 17 9 0,000 0,01833505 0,04479254 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,01833505 0,04474779 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01833505 0,04470313 ! renal water homeostasis GO:0003091 15 9 0,000 0,01833505 0,04465856 ! postreplication repair GO:0006301 25 9 0,000 0,01833505 0,04461408 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01833505 0,04456969 ! icosanoid secretion GO:0032309 15 9 0,000 0,01833505 0,04452538 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01833505 0,04448117 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01833505 0,04443704 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01833505 0,044393 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01833505 0,04434905 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01833505 0,04430518 ! sterol catabolic process GO:0016127 14 9 0,000 0,01833505 0,0442614 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01833505 0,04421771 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01833505 0,0441741 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01833505 0,04413058 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01833505 0,04408714 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01833505 0,04404379 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01833505 0,04400053 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01833505 0,04395735 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01833505 0,04391425 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01833505 0,04387124 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01833505 0,04382831 ! purine base metabolic process GO:0006144 25 9 0,000 0,01833505 0,04378547 ! pigment granule transport GO:0051904 17 9 0,000 0,01833505 0,04374271 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01833505 0,04370004 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01833505 0,04365744 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01833505 0,04361493 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01833505 0,04357251 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01833505 0,04353016 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01833505 0,0434879 ! mitochondrion localization GO:0051646 18 9 0,000 0,01833505 0,04344572 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0203517 0,04817752 ! regulation of developmental growth GO:0048638 16 10 0,000 0,0203517 0,04813089 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0203517 0,04808434 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0203517 0,04803788 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0203517 0,04799151 ! associative learning GO:0008306 21 10 0,000 0,0203517 0,04794523 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0203517 0,04789904 ! phosphate transport GO:0006817 24 10 0,000 0,0203517 0,04785294 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0203517 0,04780693 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0203517 0,047761 ! CTP metabolic process GO:0046036 11 10 0,000 0,0203517 0,04771517 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0203517 0,04766942 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0203517 0,04762376 ! GTP metabolic process GO:0046039 11 10 0,000 0,0203517 0,04757819 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0203517 0,0475327 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0203517 0,0474873 ! social behavior GO:0035176 29 10 0,000 0,0203517 0,04744199 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0203517 0,04739676 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0203517 0,04735162 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0203517 0,04730657 ! androgen metabolic process GO:0008209 17 10 0,000 0,0203517 0,0472616 ! phospholipid efflux GO:0033700 19 10 0,000 0,0203517 0,04721672 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0203517 0,04717192 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0203517 0,04712721 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0203517 0,04708258 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0203517 0,04703804 ! lung alveolus development GO:0048286 26 10 0,000 0,0203517 0,04699358 ! pathogenesis GO:0009405 17 10 0,000 0,0203517 0,0469492 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0203517 0,04690491 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0203517 0,0468607 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0203517 0,04681658 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0203517 0,04677254 ! endoderm development GO:0007492 18 10 0,000 0,0203517 0,04672858 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0203517 0,0466847 ! arginine catabolic process GO:0006527 17 10 0,000 0,0203517 0,04664091 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0203517 0,04659719 ! proline metabolic process GO:0006560 13 10 0,000 0,0203517 0,04655356 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0203517 0,04651001 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0203517 0,04646655 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0203517 0,04642316 ! V(D)J recombination GO:0033151 34 10 0,000 0,0203517 0,04637986 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0203517 0,04633663 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0203517 0,04629349 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0203517 0,04625042 ! B cell proliferation GO:0042100 19 10 0,000 0,0203517 0,04620744 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0203517 0,04616454 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0203517 0,04612171 ! multicellular organism growth GO:0035264 19 10 0,000 0,0203517 0,04607897 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0203517 0,0460363 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0203517 0,04599371 ! ruffle organization GO:0031529 17 10 0,000 0,0203517 0,04595121 ! epithelial cell development GO:0002064 21 10 0,000 0,0203517 0,04590878 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0203517 0,04586643 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0203517 0,04582415 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0203517 0,04578196 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0203517 0,04573984 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0203517 0,0456978 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0203517 0,04565584 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0203517 0,04561395 ! motor axon guidance GO:0008045 22 10 0,000 0,0203517 0,04557214 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0203517 0,04553041 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0203517 0,04548875 ! protein heterooligomerization GO:0051291 17 10 0,000 0,0203517 0,04544717 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0203517 0,04540567 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0203517 0,04536424 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0203517 0,04532289 ! segment specification GO:0007379 15 10 0,000 0,0203517 0,04528161 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0203517 0,0452404 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0203517 0,04519928 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0203517 0,04515822 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0203517 0,04511725 ! response to dsRNA GO:0043331 23 10 0,000 0,0203517 0,04507634 ! DNA ligation GO:0006266 18 10 0,000 0,0203517 0,04503551 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0203517 0,04499476 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0203517 0,04495407 ! melanosome localization GO:0032400 16 10 0,000 0,0203517 0,04491346 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0203517 0,04487293 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0203517 0,04483247 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0203517 0,04479208 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0203517 0,04475176 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0203517 0,04471152 ! induction of an organ GO:0001759 17 10 0,000 0,0203517 0,04467134 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0203517 0,04463124 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0203517 0,04459122 ! protein sumoylation GO:0016925 17 10 0,000 0,0203517 0,04455126 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0203517 0,04451137 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0203517 0,04447156 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0203517 0,04443182 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0203517 0,04439215 ! salivary gland development GO:0007431 28 10 0,000 0,0203517 0,04435255 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0203517 0,04431302 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0203517 0,04427356 ! midbrain development GO:0030901 14 10 0,000 0,0203517 0,04423417 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0203517 0,04419485 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0203517 0,0441556 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0203517 0,04411642 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0203517 0,04407731 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0203517 0,04403827 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0203517 0,0439993 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0203517 0,04396039 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0203517 0,04392156 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0203517 0,04388279 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,0203517 0,0438441 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,0203517 0,04380547 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0203517 0,04376691 ! blastocyst formation GO:0001825 18 10 0,000 0,0203517 0,04372841 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0203517 0,04368999 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0203517 0,04365163 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0203517 0,04361334 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0203517 0,04357511 ! response to nicotine GO:0035094 20 10 0,000 0,0203517 0,04353696 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0203517 0,04349887 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0203517 0,04346084 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02236426 0,04771693 ! respiratory burst GO:0045730 17 11 0,000 0,02236426 0,0476753 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02236426 0,04763373 ! neuron fate specification GO:0048665 18 11 0,000 0,02236426 0,04759224 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02236426 0,04755082 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02236426 0,04750947 ! thyroid gland development GO:0030878 26 11 0,000 0,02236426 0,04746819 ! synapsis GO:0007129 14 11 0,000 0,02236426 0,04742699 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02236426 0,04738585 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02236426 0,04734479 ! response to pain GO:0048265 27 11 0,000 0,02236426 0,0473038 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02236426 0,04726288 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02236426 0,04722203 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02236426 0,04718125 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02236426 0,04714054 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02236426 0,04709991 ! bone resorption GO:0045453 16 11 0,000 0,02236426 0,04705934 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02236426 0,04701884 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02236426 0,04697841 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02236426 0,04693805 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02236426 0,04689776 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02236426 0,04685754 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02236426 0,04681739 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02236426 0,0467773 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02236426 0,04673729 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02236426 0,04669734 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02236426 0,04665746 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02236426 0,04661765 ! UV protection GO:0009650 20 11 0,000 0,02236426 0,04657791 ! adult heart development GO:0007512 16 11 0,000 0,02236426 0,04653824 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02236426 0,04649863 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02236426 0,04645909 ! macroautophagy GO:0016236 19 11 0,000 0,02236426 0,04641962 ! temperature homeostasis GO:0001659 18 11 0,000 0,02236426 0,04638021 ! behavioral fear response GO:0001662 27 11 0,000 0,02236426 0,04634087 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02236426 0,0463016 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02236426 0,0462624 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02236426 0,04622326 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02236426 0,04618418 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02236426 0,04614518 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02236426 0,04610624 ! regulation of organ growth GO:0046620 14 11 0,000 0,02236426 0,04606736 ! pigment granule localization GO:0051875 20 11 0,000 0,02236426 0,04602855 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02236426 0,04598981 ! vasoconstriction GO:0042310 20 11 0,000 0,02236426 0,04595113 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02236426 0,04591251 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02236426 0,04587396 ! embryonic axis specification GO:0000578 19 11 0,000 0,02236426 0,04583548 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02236426 0,04579706 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02236426 0,0457587 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02236426 0,04572041 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02236426 0,04568218 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02236426 0,04564402 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02236426 0,04560592 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02236426 0,04556788 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02236426 0,04552991 ! prophase GO:0051324 17 11 0,000 0,02236426 0,045492 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02236426 0,04545415 ! nucleosome positioning GO:0016584 15 11 0,000 0,02236426 0,04541637 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02236426 0,04537865 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02236426 0,04534099 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02236426 0,04530339 ! apical protein localization GO:0045176 18 11 0,000 0,02236426 0,04526586 ! acid secretion GO:0046717 20 11 0,000 0,02236426 0,04522839 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02236426 0,04519098 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02236426 0,04515363 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02236426 0,04511634 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02236426 0,04507912 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02236426 0,04504195 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02236426 0,04500485 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02236426 0,04496781 ! cholesterol efflux GO:0033344 21 11 0,000 0,02236426 0,04493083 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02236426 0,04489391 ! oocyte development GO:0048599 20 11 0,000 0,02236426 0,04485705 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02236426 0,04482025 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02236426 0,04478352 ! embryonic gut development GO:0048566 19 11 0,000 0,02236426 0,04474684 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02236426 0,04471022 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02236426 0,04467366 ! activation of innate immune response GO:0002218 16 11 0,000 0,02236426 0,04463717 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02236426 0,04460073 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02236426 0,04456435 ! lysogeny GO:0030069 22 11 0,000 0,02236426 0,04452803 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02236426 0,04449177 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02236426 0,04445557 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02236426 0,04441942 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02236426 0,04438334 ! nucleus localization GO:0051647 22 11 0,000 0,02236426 0,04434731 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02437274 0,04829085 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02437274 0,04825171 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02437274 0,04821264 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02437274 0,04817364 ! virus-host interaction GO:0019048 30 12 0,000 0,02437274 0,04813469 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02437274 0,04809581 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02437274 0,04805699 ! protein complex disassembly GO:0043241 28 12 0,000 0,02437274 0,04801824 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02437274 0,04797954 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02437274 0,04794091 ! hippocampus development GO:0021766 29 12 0,000 0,02437274 0,04790234 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02437274 0,04786384 ! T cell proliferation GO:0042098 32 12 0,000 0,02437274 0,04782539 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02437274 0,04778701 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02437274 0,04774869 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02437274 0,04771043 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02437274 0,04767223 ! drug transport GO:0015893 16 12 0,000 0,02437274 0,04763409 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02437274 0,04759601 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02437274 0,047558 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02437274 0,04752004 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02437274 0,04748215 ! focal adhesion formation GO:0048041 37 12 0,000 0,02437274 0,04744431 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02437274 0,04740654 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02437274 0,04736883 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02437274 0,04733117 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02437274 0,04729358 ! lipid digestion GO:0044241 21 12 0,000 0,02437274 0,04725604 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02437274 0,04721857 ! entry into host cell GO:0030260 34 12 0,000 0,02437274 0,04718115 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02437274 0,0471438 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02437274 0,0471065 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02437274 0,04706926 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02437274 0,04703208 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02437274 0,04699496 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02437274 0,0469579 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02437274 0,04692089 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02437274 0,04688395 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02437274 0,04684706 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02437274 0,04681023 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02437274 0,04677346 ! cranial nerve development GO:0021545 23 12 0,000 0,02437274 0,04673674 ! fucose catabolic process GO:0019317 25 12 0,000 0,02437274 0,04670009 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02437274 0,04666349 ! histone acetylation GO:0016573 27 12 0,000 0,02437274 0,04662695 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02437274 0,04659046 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02437274 0,04655404 ! zymogen activation GO:0031638 18 12 0,000 0,02437274 0,04651767 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02437274 0,04648135 ! T cell homeostasis GO:0043029 28 12 0,000 0,02437274 0,0464451 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02437274 0,0464089 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02437274 0,04637275 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02437274 0,04633666 ! oocyte differentiation GO:0009994 21 12 0,000 0,02437274 0,04630063 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02437274 0,04626466 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02437274 0,04622874 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,02437274 0,04619287 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02437274 0,04615706 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02437274 0,04612131 ! defense response to fungus GO:0050832 15 12 0,000 0,02437274 0,04608561 ! developmental induction GO:0031128 22 12 0,000 0,02437274 0,04604997 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02437274 0,04601438 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02437274 0,04597885 ! response to cold GO:0009409 17 12 0,000 0,02437274 0,04594337 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02437274 0,04590795 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02437274 0,04587258 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02637716 0,04960692 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02637716 0,04956876 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02637716 0,04953066 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02637716 0,04949262 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02637716 0,04945464 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02637716 0,04941671 ! peroxisomal transport GO:0043574 28 13 0,000 0,02637716 0,04937885 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02637716 0,04934104 ! cartilage condensation GO:0001502 22 13 0,000 0,02637716 0,04930328 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02637716 0,04926559 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02637716 0,04922796 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02637716 0,04919038 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02637716 0,04915286 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02637716 0,04911539 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02637716 0,04907798 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02637716 0,04904063 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02637716 0,04900334 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02637716 0,0489661 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02637716 0,04892892 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02637716 0,0488918 ! methionine metabolic process GO:0006555 31 13 0,000 0,02637716 0,04885473 ! plasma membrane organization GO:0007009 27 13 0,000 0,02637716 0,04881772 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02637716 0,04878077 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02637716 0,04874387 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02637716 0,04870702 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02637716 0,04867024 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02637716 0,0486335 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02637716 0,04859683 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02637716 0,04856021 ! exocrine system development GO:0035272 34 13 0,000 0,02637716 0,04852364 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02637716 0,04848713 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02637716 0,04845067 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02637716 0,04841427 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02637716 0,04837792 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02637716 0,04834163 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02637716 0,04830539 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02637716 0,04826921 ! protein homotetramerization GO:0051289 24 13 0,000 0,02637716 0,04823308 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02637716 0,048197 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02637716 0,04816098 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02637716 0,04812501 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02637716 0,0480891 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02637716 0,04805324 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02637716 0,04801743 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02637716 0,04798168 ! histone methylation GO:0016571 29 13 0,000 0,02637716 0,04794598 ! chromatin silencing GO:0006342 29 13 0,000 0,02637716 0,04791033 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02637716 0,04787473 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02637716 0,04783919 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02637716 0,0478037 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02637716 0,04776827 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02637716 0,04773288 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02637716 0,04769755 ! spleen development GO:0048536 24 13 0,000 0,02637716 0,04766227 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02637716 0,04762705 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02637716 0,04759187 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02637716 0,04755675 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02637716 0,04752168 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02637716 0,04748666 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02637716 0,04745169 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02637716 0,04741677 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02637716 0,04738191 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02637716 0,04734709 ! insulin secretion GO:0030073 24 13 0,000 0,02637716 0,04731233 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02637716 0,04727762 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02637716 0,04724296 ! acrosome reaction GO:0007340 19 13 0,000 0,02637716 0,04720835 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02637716 0,04717379 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02637716 0,04713928 ! rRNA transcription GO:0009303 28 14 0,000 0,02837751 0,05067708 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02837751 0,05064007 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02837751 0,0506031 ! water transport GO:0006833 21 14 0,000 0,02837751 0,05056619 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02837751 0,05052934 ! non-recombinational repair GO:0000726 29 14 0,000 0,02837751 0,05049253 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02837751 0,05045579 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02837751 0,05041909 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02837751 0,05038245 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02837751 0,05034586 ! palate development GO:0060021 32 14 0,000 0,02837751 0,05030933 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02837751 0,05027284 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02837751 0,05023641 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02837751 0,05020004 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02837751 0,05016371 ! arginine metabolic process GO:0006525 21 14 0,000 0,02837751 0,05012744 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02837751 0,05009122 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02837751 0,05005505 ! regulation of heart rate GO:0002027 25 14 0,000 0,02837751 0,05001894 ! fear response GO:0042596 34 14 0,000 0,02837751 0,04998288 ! organic alcohol transport GO:0015850 29 14 0,000 0,02837751 0,04994687 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02837751 0,04991091 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02837751 0,049875 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02837751 0,04983914 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02837751 0,04980334 ! bone mineralization GO:0030282 18 14 0,000 0,02837751 0,04976759 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02837751 0,04973189 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02837751 0,04969624 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02837751 0,04966064 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02837751 0,04962509 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02837751 0,04958959 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02837751 0,04955415 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02837751 0,04951875 ! ribosome assembly GO:0042255 18 14 0,000 0,02837751 0,0494834 ! cerebellum development GO:0021549 23 14 0,000 0,02837751 0,04944811 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02837751 0,04941287 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02837751 0,04937767 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02837751 0,04934253 ! response to gamma radiation GO:0010332 30 14 0,000 0,02837751 0,04930743 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02837751 0,04927239 ! NADP metabolic process GO:0006739 24 14 0,000 0,02837751 0,04923739 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02837751 0,04920245 ! oxygen transport GO:0015671 22 14 0,000 0,02837751 0,04916755 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02837751 0,04913271 ! male genitalia development GO:0030539 26 14 0,000 0,02837751 0,04909791 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02837751 0,04906316 ! regulation of axon extension GO:0030516 43 14 0,000 0,02837751 0,04902847 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,02837751 0,04899382 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02837751 0,04895922 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0303738 0,05236641 ! lactation GO:0007595 30 15 0,000 0,0303738 0,05232948 ! reproductive cellular process GO:0048610 22 15 0,000 0,0303738 0,0522926 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0303738 0,05225578 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0303738 0,052219 ! superoxide anion generation GO:0042554 22 15 0,000 0,0303738 0,05218228 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0303738 0,05214561 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0303738 0,05210899 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0303738 0,05207242 ! copper ion transport GO:0006825 22 15 0,000 0,0303738 0,05203591 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0303738 0,05199944 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0303738 0,05196303 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0303738 0,05192667 ! sulfate transport GO:0008272 27 15 0,000 0,0303738 0,05189035 ! response to cAMP GO:0051591 25 15 0,000 0,0303738 0,05185409 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0303738 0,05181788 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0303738 0,05178172 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0303738 0,05174561 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0303738 0,05170955 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0303738 0,05167354 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0303738 0,05163758 ! vesicle coating GO:0006901 38 15 0,000 0,0303738 0,05160167 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0303738 0,05156581 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0303738 0,05153 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0303738 0,05149424 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0303738 0,05145853 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0303738 0,05142287 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0303738 0,05138726 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0303738 0,0513517 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0303738 0,05131619 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0303738 0,05128072 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0303738 0,05124531 ! histone deacetylation GO:0016575 24 15 0,000 0,0303738 0,05120994 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0303738 0,05117462 ! water homeostasis GO:0030104 28 15 0,000 0,0303738 0,05113936 ! cofactor transport GO:0051181 30 15 0,000 0,0303738 0,05110414 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0303738 0,05106896 ! muscle maintenance GO:0046716 26 15 0,000 0,0303738 0,05103384 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0303738 0,05099877 ! intestinal absorption GO:0050892 31 15 0,000 0,0303738 0,05096374 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0303738 0,05092876 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0303738 0,05089383 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0303738 0,05085895 ! cell killing GO:0001906 32 15 0,000 0,0303738 0,05082411 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0303738 0,05078933 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0303738 0,05075459 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0303738 0,05071989 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0303738 0,05068525 ! actin filament polymerization GO:0030041 27 15 0,000 0,0303738 0,05065065 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0303738 0,0506161 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03236606 0,0538993 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03236606 0,05386259 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03236606 0,05382592 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03236606 0,0537893 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03236606 0,05375274 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03236606 0,05371622 ! bone remodeling GO:0046849 28 16 0,000 0,03236606 0,05367975 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03236606 0,05364333 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03236606 0,05360697 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03236606 0,05357065 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03236606 0,05353438 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03236606 0,05349816 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03236606 0,05346198 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03236606 0,05342586 ! startle response GO:0001964 28 16 0,000 0,03236606 0,05338979 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03236606 0,05335376 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,03236606 0,05331779 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03236606 0,05328186 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03236606 0,05324598 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03236606 0,05321015 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03236606 0,05317436 ! pituitary gland development GO:0021983 30 16 0,000 0,03236606 0,05313863 ! response to osmotic stress GO:0006970 27 16 0,000 0,03236606 0,05310294 ! lysosomal transport GO:0007041 31 16 0,000 0,03236606 0,0530673 ! fructose metabolic process GO:0006000 25 16 0,000 0,03236606 0,05303171 ! L-amino acid transport GO:0015807 33 16 0,000 0,03236606 0,05299616 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03236606 0,05296067 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03236606 0,05292522 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03236606 0,05288982 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03236606 0,05285446 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03236606 0,05281916 ! axon cargo transport GO:0008088 46 16 0,000 0,03236606 0,0527839 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03236606 0,05274868 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03236606 0,05271352 ! DNA replication initiation GO:0006270 28 16 0,000 0,03236606 0,0526784 ! neuron recognition GO:0008038 40 16 0,000 0,03236606 0,05264333 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03236606 0,0526083 ! tissue regeneration GO:0042246 27 16 0,000 0,03236606 0,05257332 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03236606 0,05253839 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03236606 0,0525035 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03236606 0,05246866 ! biomineral formation GO:0031214 22 16 0,000 0,03236606 0,05243387 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03236606 0,05239912 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03236606 0,05236442 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03236606 0,05232977 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03236606 0,05229516 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03236606 0,05226059 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03236606 0,05222607 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03236606 0,0521916 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,03236606 0,05215717 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03236606 0,05212279 ! peptide hormone processing GO:0016486 27 16 0,000 0,03236606 0,05208846 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03435427 0,0552518 ! metencephalon development GO:0022037 32 17 0,000 0,03435427 0,05521545 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03435427 0,05517915 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03435427 0,05514289 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03435427 0,05510669 ! signal complex assembly GO:0007172 47 17 0,000 0,03435427 0,05507053 ! filopodium assembly GO:0046847 42 17 0,000 0,03435427 0,05503442 ! endothelial cell migration GO:0043542 31 17 0,000 0,03435427 0,05499835 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03435427 0,05496233 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03435427 0,05492636 ! glial cell development GO:0021782 28 17 0,000 0,03435427 0,05489044 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03435427 0,05485456 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03435427 0,05481873 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03435427 0,05478295 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03435427 0,05474722 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03435427 0,05471153 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03435427 0,05467588 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03435427 0,05464029 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,03435427 0,05460474 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03435427 0,05456923 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03435427 0,05453378 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03435427 0,05449837 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03435427 0,054463 ! membrane budding GO:0006900 42 17 0,000 0,03435427 0,05442768 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03435427 0,05439241 ! regulation of protein binding GO:0043393 33 17 0,000 0,03435427 0,05435718 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03435427 0,054322 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03435427 0,05428686 ! genitalia development GO:0048806 32 17 0,000 0,03435427 0,05425177 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03435427 0,05421672 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,03435427 0,05418172 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03435427 0,05414676 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03435427 0,05411185 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03435427 0,05407699 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03435427 0,05404217 ! steroid catabolic process GO:0006706 34 17 0,000 0,03435427 0,05400739 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03435427 0,05397266 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03435427 0,05393797 ! gas transport GO:0015669 26 17 0,000 0,03435427 0,05390333 ! organic cation transport GO:0015695 32 17 0,000 0,03435427 0,05386873 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03435427 0,05383418 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03435427 0,05379967 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03435427 0,0537652 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03633846 0,05683409 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03633846 0,05679773 ! limbic system development GO:0021761 40 18 0,000 0,03633846 0,05676141 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03633846 0,05672514 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03633846 0,05668892 ! adult walking behavior GO:0007628 36 18 0,000 0,03633846 0,05665274 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03633846 0,05661661 ! heart looping GO:0001947 34 18 0,000 0,03633846 0,05658053 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03633846 0,05654449 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03633846 0,0565085 ! centrosome cycle GO:0007098 26 18 0,000 0,03633846 0,05647255 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03633846 0,05643665 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03633846 0,05640079 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03633846 0,05636498 ! glycine metabolic process GO:0006544 30 18 0,000 0,03633846 0,05632922 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03633846 0,0562935 ! response to retinoic acid GO:0032526 31 18 0,000 0,03633846 0,05625782 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03633846 0,0562222 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03633846 0,05618661 ! DNA integration GO:0015074 32 18 0,000 0,03633846 0,05615107 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03633846 0,05611558 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03633846 0,05608013 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03633846 0,05604473 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03633846 0,05600937 ! neural crest cell migration GO:0001755 41 18 0,000 0,03633846 0,05597405 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03633846 0,05593878 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03633846 0,05590356 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03633846 0,05586837 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03633846 0,05583324 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03633846 0,05579814 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03633846 0,05576309 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03633846 0,05572809 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03633846 0,05569313 ! detection of bacterium GO:0016045 22 18 0,000 0,03633846 0,05565821 ! nerve development GO:0021675 34 18 0,000 0,03633846 0,05562334 ! defense response to virus GO:0051607 43 18 0,000 0,03633846 0,05558851 ! microspike assembly GO:0030035 46 18 0,000 0,03633846 0,05555372 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03633846 0,05551898 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03633846 0,05548428 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03831862 0,0584712 ! positive regulation of translation GO:0045727 31 19 0,000 0,03831862 0,0584347 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03831862 0,05839824 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,03831862 0,05836184 ! neuron maturation GO:0042551 46 19 0,000 0,03831862 0,05832547 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03831862 0,05828916 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03831862 0,05825289 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03831862 0,05821666 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03831862 0,05818048 ! inositol metabolic process GO:0006020 33 19 0,000 0,03831862 0,05814434 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03831862 0,05810825 ! memory GO:0007613 34 19 0,000 0,03831862 0,0580722 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03831862 0,0580362 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03831862 0,05800024 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03831862 0,05796433 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03831862 0,05792846 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03831862 0,05789263 ! cerebral cortex development GO:0021987 40 19 0,000 0,03831862 0,05785685 ! pigmentation during development GO:0048066 42 19 0,000 0,03831862 0,05782112 ! response to vitamin A GO:0033189 32 19 0,000 0,03831862 0,05778542 ! heme metabolic process GO:0042168 40 19 0,000 0,03831862 0,05774978 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03831862 0,05771417 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03831862 0,05767861 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03831862 0,0576431 ! response to fungus GO:0009620 26 19 0,000 0,03831862 0,05760762 ! peptide cross-linking GO:0018149 39 19 0,000 0,03831862 0,05757219 ! protein export from nucleus GO:0006611 40 19 0,000 0,03831862 0,05753681 ! heart process GO:0003015 32 19 0,000 0,03831862 0,05750147 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03831862 0,05746617 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03831862 0,05743091 ! visual learning GO:0008542 38 19 0,000 0,03831862 0,0573957 ! cellular pigmentation GO:0033059 37 19 0,000 0,03831862 0,05736053 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03831862 0,05732541 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03831862 0,05729032 ! vitamin transport GO:0051180 31 19 0,000 0,03831862 0,05725528 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03831862 0,05722029 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03831862 0,05718533 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03831862 0,05715042 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03831862 0,05711555 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03831862 0,05708072 ! cilium assembly GO:0042384 38 19 0,000 0,03831862 0,05704594 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03831862 0,0570112 ! protein secretion GO:0009306 45 20 0,000 0,04029477 0,05991486 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04029477 0,05987842 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04029477 0,05984202 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04029477 0,05980566 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04029477 0,05976935 ! skin development GO:0043588 42 20 0,000 0,04029477 0,05973308 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04029477 0,05969686 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04029477 0,05966068 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04029477 0,05962454 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04029477 0,05958845 ! response to vitamin GO:0033273 36 20 0,000 0,04029477 0,0595524 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04029477 0,0595164 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04029477 0,05948044 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04029477 0,05944452 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04029477 0,05940864 ! response to alkaloid GO:0043279 38 20 0,000 0,04029477 0,05937281 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04029477 0,05933702 GO:0016101|diterpenoid metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,04029477 0,05930128 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04029477 0,05926558 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04029477 0,05922992 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04029477 0,0591943 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04029477 0,05915873 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04029477 0,0591232 ! body fluid secretion GO:0007589 33 20 0,000 0,04029477 0,05908771 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04029477 0,05905226 ! peptide secretion GO:0002790 38 20 0,000 0,04029477 0,05901686 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04029477 0,0589815 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04029477 0,05894618 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04029477 0,0589109 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04029477 0,05887567 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04029477 0,05884048 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04029477 0,05880533 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04029477 0,05877022 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04029477 0,05873516 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04029477 0,05870013 ! regulation of glucose import GO:0046324 30 20 0,000 0,04029477 0,05866515 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04029477 0,05863021 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,04029477 0,05859531 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04029477 0,05856045 ! negative regulation of translation GO:0017148 32 20 0,000 0,04029477 0,05852564 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04029477 0,05849086 ! regulation of cell killing GO:0031341 46 21 0,000 0,04226691 0,06131715 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04226691 0,06128076 ! hormone secretion GO:0046879 39 21 0,000 0,04226691 0,06124441 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04226691 0,0612081 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04226691 0,06117184 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04226691 0,06113563 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04226691 0,06109945 ! ovarian follicle development GO:0001541 39 21 0,000 0,04226691 0,06106332 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04226691 0,06102723 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04226691 0,06099118 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,04226691 0,06095518 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04226691 0,06091922 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04226691 0,0608833 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04226691 0,06084742 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04226691 0,06081159 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,04226691 0,06077579 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04226691 0,06074004 ! diencephalon development GO:0021536 36 21 0,000 0,04226691 0,06070433 ! collagen fibril organization GO:0030199 62 21 0,000 0,04226691 0,06066867 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04226691 0,06063304 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04226691 0,06059746 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04226691 0,06056192 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04226691 0,06052642 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04226691 0,06049096 ! collagen catabolic process GO:0030574 29 21 0,000 0,04226691 0,06045555 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04226691 0,06042017 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04226691 0,06038484 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04226691 0,06034955 ! actin filament-based movement GO:0030048 47 21 0,000 0,04226691 0,06031429 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04226691 0,06027908 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04423506 0,06304916 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04423506 0,0630124 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04423506 0,06297567 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04423506 0,062939 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04423506 0,06290236 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 59 22 0,000 0,04423506 0,06286577 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04423506 0,06282922 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04423506 0,06279271 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04423506 0,06275625 ! cellular response to starvation GO:0009267 37 22 0,000 0,04423506 0,06271982 ! vacuolar transport GO:0007034 41 22 0,000 0,04423506 0,06268344 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04423506 0,06264711 ! fucose metabolic process GO:0006004 44 22 0,000 0,04423506 0,06261081 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04423506 0,06257456 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04423506 0,06253834 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,04423506 0,06250217 ! ureteric bud development GO:0001657 50 22 0,000 0,04423506 0,06246604 ! cell aging GO:0007569 48 22 0,000 0,04423506 0,06242996 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04423506 0,06239391 ! cytolysis GO:0019835 27 22 0,000 0,04423506 0,06235791 ! renal system process GO:0003014 42 22 0,000 0,04423506 0,06232195 ! vasodilation GO:0042311 40 22 0,000 0,04423506 0,06228603 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,04423506 0,06225015 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04423506 0,06221431 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04423506 0,06217851 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04423506 0,06214276 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04423506 0,06210704 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04423506 0,06207137 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04423506 0,06203574 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04423506 0,06200015 ! sarcomere organization GO:0045214 32 22 0,000 0,04423506 0,0619646 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04423506 0,06192909 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04423506 0,06189362 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04423506 0,06185819 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04423506 0,0618228 ! gut development GO:0048565 44 22 0,000 0,04423506 0,06178745 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04423506 0,06175215 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04423506 0,06171688 ! protein stabilization GO:0050821 41 22 0,000 0,04423506 0,06168165 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04619922 0,06438374 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04619922 0,06434703 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04619922 0,06431037 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04619922 0,06427375 ! gluconeogenesis GO:0006094 38 23 0,000 0,04619922 0,06423716 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04619922 0,06420062 ! viral genome replication GO:0019079 44 23 0,000 0,04619922 0,06416413 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04619922 0,06412767 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04619922 0,06409125 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04619922 0,06405488 ! regeneration GO:0031099 42 23 0,000 0,04619922 0,06401855 ! axis specification GO:0009798 43 23 0,000 0,04619922 0,06398225 ! visual behavior GO:0007632 46 23 0,000 0,04619922 0,063946 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04619922 0,06390979 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04619922 0,06387363 ! response to ethanol GO:0045471 47 23 0,000 0,04619922 0,0638375 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04619922 0,06380141 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,04619922 0,06376537 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04619922 0,06372936 ! peroxisome organization GO:0007031 43 23 0,000 0,04619922 0,0636934 ! lysosome organization GO:0007040 47 23 0,000 0,04619922 0,06365747 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04619922 0,06362159 ! vesicle targeting GO:0006903 49 23 0,000 0,04619922 0,06358574 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04619922 0,06354994 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04619922 0,06351418 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04619922 0,06347846 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04619922 0,06344278 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04619922 0,06340713 ! DNA modification GO:0006304 36 23 0,000 0,04619922 0,06337153 ! fatty acid transport GO:0015908 47 23 0,000 0,04619922 0,06333597 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04619922 0,06330045 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04619922 0,06326496 ! hormone transport GO:0009914 41 23 0,000 0,04619922 0,06322952 ! cell-cell recognition GO:0009988 28 23 0,000 0,04619922 0,06319412 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04619922 0,06315876 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04619922 0,06312343 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04619922 0,06308815 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0481594 0,06572816 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0481594 0,06569146 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0481594 0,0656548 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0481594 0,06561819 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,0481594 0,06558161 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0481594 0,06554508 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0481594 0,06550858 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0481594 0,06547213 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0481594 0,06543571 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0481594 0,06539934 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0481594 0,06536301 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0481594 0,06532671 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,0481594 0,06529046 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0481594 0,06525425 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0481594 0,06521808 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0481594 0,06518194 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0481594 0,06514585 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0481594 0,0651098 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0481594 0,06507379 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0481594 0,06503782 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0481594 0,06500188 ! pallium development GO:0021543 56 24 0,000 0,0481594 0,06496599 ! oogenesis GO:0048477 44 24 0,000 0,0481594 0,06493014 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0481594 0,06489432 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0481594 0,06485855 ! platelet activation GO:0030168 41 24 0,000 0,0481594 0,06482282 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0481594 0,06478712 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0481594 0,06475146 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0481594 0,06471585 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0481594 0,06468027 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0481594 0,06464473 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0481594 0,06460923 ! regulation of amine transport GO:0051952 41 24 0,000 0,0481594 0,06457377 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0501156 0,06715986 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0501156 0,06712304 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0501156 0,06708626 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0501156 0,06704952 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0501156 0,06701282 ! phototransduction GO:0007602 37 25 0,000 0,0501156 0,06697616 ! keratinization GO:0031424 37 25 0,000 0,0501156 0,06693954 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0501156 0,06690296 ! vacuole organization GO:0007033 49 25 0,000 0,0501156 0,06686642 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0501156 0,06682992 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0501156 0,06679346 ! receptor metabolic process GO:0043112 53 25 0,000 0,0501156 0,06675704 ! chromosome condensation GO:0030261 48 25 0,000 0,0501156 0,06672066 ! regulation of behavior GO:0050795 48 25 0,000 0,0501156 0,06668432 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0501156 0,06664802 ! interaction with host GO:0051701 66 25 0,000 0,0501156 0,06661176 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0501156 0,06657554 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0501156 0,06653936 ! immunoglobulin production GO:0002377 62 25 0,000 0,0501156 0,06650321 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0501156 0,06646711 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,0501156 0,06643105 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0501156 0,06639502 ! liver development GO:0001889 55 25 0,000 0,0501156 0,06635903 ! protein tetramerization GO:0051262 57 25 0,000 0,0501156 0,06632309 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05206784 0,06886937 ! myelination GO:0042552 50 26 0,000 0,05206784 0,06883211 ! initiation of viral infection GO:0019059 60 26 0,000 0,05206784 0,06879488 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05206784 0,06875769 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05206784 0,06872055 ! molting cycle process GO:0022404 52 26 0,000 0,05206784 0,06868344 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05206784 0,06864638 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05206784 0,06860935 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05206784 0,06857236 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05206784 0,06853542 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05206784 0,06849851 ! digestive system process GO:0022600 49 26 0,000 0,05206784 0,06846164 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05206784 0,06842482 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,05206784 0,06838803 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05206784 0,06835128 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05206784 0,06831457 ! neural crest cell development GO:0014032 59 26 0,000 0,05206784 0,0682779 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05206784 0,06824127 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05206784 0,06820468 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05206784 0,06816813 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05206784 0,06813162 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05206784 0,06809515 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05206784 0,06805871 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05206784 0,06802232 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05206784 0,06798596 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05206784 0,06794964 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05206784 0,06791337 ! blastocyst development GO:0001824 50 26 0,000 0,05206784 0,06787713 ! telomere organization GO:0032200 46 26 0,000 0,05206784 0,06784093 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05206784 0,06780476 ! neural tube closure GO:0001843 58 26 0,000 0,05206784 0,06776864 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05206784 0,06773255 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05206784 0,06769651 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05206784 0,0676605 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05401612 0,07015491 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05401612 0,07011763 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05401612 0,0700804 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05401612 0,0700432 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05401612 0,07000604 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05401612 0,06996892 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05401612 0,06993184 ! iron ion transport GO:0006826 65 27 0,000 0,05401612 0,0698948 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05401612 0,0698578 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05401612 0,06982084 ! tube lumen formation GO:0035148 59 27 0,000 0,05401612 0,06978392 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05401612 0,06974703 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,05401612 0,06971019 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05401612 0,06967338 ! response to starvation GO:0042594 47 27 0,000 0,05401612 0,06963662 ! response to toxin GO:0009636 49 27 0,000 0,05401612 0,06959989 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05401612 0,0695632 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05401612 0,06952655 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,05401612 0,06948993 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05401612 0,06945336 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05401612 0,06941683 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,05401612 0,06938033 ! neuron fate commitment GO:0048663 52 28 0,000 0,05596045 0,07183993 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05596045 0,0718022 ! protein amino acid acylation GO:0043543 59 28 0,000 0,05596045 0,07176451 ! circadian rhythm GO:0007623 56 28 0,000 0,05596045 0,07172686 ! dendrite development GO:0016358 67 28 0,000 0,05596045 0,07168924 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05596045 0,07165167 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05596045 0,07161414 ! sperm motility GO:0030317 37 28 0,000 0,05596045 0,07157664 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05596045 0,07153919 ! base-excision repair GO:0006284 41 28 0,000 0,05596045 0,07150177 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05596045 0,07146439 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05596045 0,07142706 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05596045 0,07138976 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05596045 0,0713525 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05596045 0,07131528 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05596045 0,0712781 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,05596045 0,07124095 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05596045 0,07120385 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,05596045 0,07116678 ! lipid oxidation GO:0034440 48 28 0,000 0,05596045 0,07112975 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05596045 0,07109277 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05596045 0,07105581 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05790084 0,07348143 ! translational initiation GO:0006413 66 29 0,000 0,05790084 0,07344328 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05790084 0,07340517 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05790084 0,0733671 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05790084 0,07332906 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,05790084 0,07329107 ! autophagy GO:0006914 47 29 0,000 0,05790084 0,07325311 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05790084 0,0732152 ! primary neural tube formation GO:0014020 61 29 0,000 0,05790084 0,07317732 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05790084 0,07313948 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05790084 0,07310168 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,05790084 0,07306393 ! somitogenesis GO:0001756 52 29 0,000 0,05790084 0,07302621 ! synaptogenesis GO:0007416 46 29 0,000 0,05790084 0,07298852 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05790084 0,07295088 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05790084 0,07291328 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05790084 0,07287571 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05790084 0,07283819 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0598373 0,07523547 ! phenol metabolic process GO:0018958 56 30 0,000 0,0598373 0,07519677 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0598373 0,07515811 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0598373 0,07511949 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0598373 0,07508091 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0598373 0,07504236 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0598373 0,07500386 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0598373 0,0749654 ! acute-phase response GO:0006953 50 30 0,000 0,0598373 0,07492697 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0598373 0,07488859 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0598373 0,07485024 ! myofibril assembly GO:0030239 50 30 0,000 0,0598373 0,07481194 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,0598373 0,07477367 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0598373 0,07473544 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0598373 0,07469725 ! phospholipid transport GO:0015914 65 30 0,000 0,0598373 0,0746591 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,0598373 0,07462099 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0598373 0,07458292 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0598373 0,07454489 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,0598373 0,07450689 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,0598373 0,07446894 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06176983 0,07683487 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06176983 0,07679577 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06176983 0,07675671 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06176983 0,07671769 ! cell junction assembly GO:0034329 85 31 0,000 0,06176983 0,07667871 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06176983 0,07663976 ! ovulation cycle process GO:0022602 55 31 0,000 0,06176983 0,07660086 ! peptide transport GO:0015833 60 31 0,000 0,06176983 0,076562 ! male gonad development GO:0008584 56 31 0,000 0,06176983 0,07652317 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06176983 0,07648439 ! detection of light stimulus GO:0009583 44 31 0,000 0,06176983 0,07644564 ! natural killer cell activation GO:0030101 50 31 0,000 0,06176983 0,07640693 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06176983 0,07636827 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06176983 0,07632964 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,06176983 0,07629105 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06176983 0,0762525 ! eye morphogenesis GO:0048592 65 31 0,000 0,06176983 0,07621399 ! response to heat GO:0009408 54 31 0,000 0,06176983 0,07617551 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06176983 0,07613708 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06369844 0,07847468 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06369844 0,07843513 ! collagen metabolic process GO:0032963 49 32 0,000 0,06369844 0,07839561 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06369844 0,07835614 ! spindle organization GO:0007051 50 32 0,000 0,06369844 0,07831671 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06369844 0,07827731 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06369844 0,07823796 ! metanephros development GO:0001656 81 32 0,000 0,06369844 0,07819864 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06369844 0,07815936 ! muscle cell development GO:0055001 52 32 0,000 0,06369844 0,07812013 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06369844 0,07808093 ! ovulation cycle GO:0042698 57 32 0,000 0,06369844 0,07804177 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06369844 0,07800265 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06369844 0,07796357 ! hindbrain development GO:0030902 65 32 0,000 0,06369844 0,07792453 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06369844 0,07788553 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06369844 0,07784657 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,06369844 0,07780765 ! gene silencing GO:0016458 71 32 0,000 0,06369844 0,07776876 ! regulation of pH GO:0006885 56 33 0,000 0,06562314 0,08007859 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06562314 0,08003861 ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06562314 0,07999867 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06562314 0,07995877 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06562314 0,07991891 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06562314 0,07987909 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06562314 0,07983931 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06562314 0,07979957 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06562314 0,07975987 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06562314 0,07972021 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06562314 0,07968059 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06562314 0,079641 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06562314 0,07960146 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06754394 0,08189075 ! glial cell differentiation GO:0010001 67 34 0,000 0,06754394 0,08185013 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06754394 0,08180955 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06754394 0,08176901 ! spliceosome assembly GO:0000245 75 34 0,000 0,06754394 0,08172851 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06754394 0,08168805 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,06754394 0,08164763 ! cell fate specification GO:0001708 56 34 0,000 0,06754394 0,08160725 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06754394 0,08156691 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06754394 0,08152661 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,06754394 0,08148635 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06946085 0,08375758 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06946085 0,08371626 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06946085 0,08367498 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06946085 0,08363374 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06946085 0,08359254 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06946085 0,08355138 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06946085 0,08351026 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06946085 0,08346918 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06946085 0,08342815 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06946085 0,08338715 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06946085 0,08334619 ! telencephalon development GO:0021537 81 35 0,000 0,06946085 0,08330528 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06946085 0,0832644 ! placenta development GO:0001890 53 35 0,000 0,06946085 0,08322357 ! vesicle localization GO:0051648 70 35 0,000 0,06946085 0,08318277 ! regulation of muscle development GO:0048634 82 36 0,000 0,07137387 0,08543182 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07137387 0,08538999 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07137387 0,08534819 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07137387 0,08530644 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07137387 0,08526472 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07137387 0,08522305 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07137387 0,08518141 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07137387 0,08513982 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07137387 0,08509827 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,07137387 0,08505676 ! aerobic respiration GO:0009060 56 36 0,000 0,07137387 0,08501529 ! cytokine production GO:0001816 68 36 0,000 0,07137387 0,08497386 ! embryonic organ development GO:0048568 67 36 0,000 0,07137387 0,08493247 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07137387 0,08489112 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07137387 0,08484981 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07328301 0,08707703 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07328301 0,0870347 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07328301 0,08699241 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07328301 0,08695016 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07328301 0,08690795 ! odontogenesis GO:0042476 74 37 0,000 0,07328301 0,08686578 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07328301 0,08682366 ! cell junction organization GO:0034330 96 37 0,000 0,07328301 0,08678157 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07328301 0,08673953 ! female gonad development GO:0008585 71 37 0,000 0,07328301 0,08669752 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07328301 0,08665556 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,07328301 0,08661363 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,07518827 0,08882251 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07518827 0,08877958 ! meiosis I GO:0007127 74 38 0,000 0,07518827 0,08873669 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07518827 0,08869384 ! organic anion transport GO:0015711 82 38 0,000 0,07518827 0,08865104 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07518827 0,08860827 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07518827 0,08856555 ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07518827 0,08852287 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07518827 0,08848023 ! regulation of protein stability GO:0031647 77 38 0,000 0,07518827 0,08843763 ! spermatid development GO:0007286 69 38 0,000 0,07518827 0,08839507 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07518827 0,08835255 ! pigment metabolic process GO:0042440 87 38 0,000 0,07518827 0,08831007 ! neural tube formation GO:0001841 79 38 0,000 0,07518827 0,08826764 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,07708968 0,09045633 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,07708968 0,0904129 ! negative regulation of binding GO:0051100 71 39 0,000 0,07708968 0,09036952 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,07708968 0,09032618 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,07708968 0,09028288 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,07708968 0,09023962 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,07708968 0,0901964 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,07708968 0,09015322 ! glucan metabolic process GO:0044042 64 39 0,000 0,07708968 0,09011009 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07898723 0,09228397 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07898723 0,09223986 ! learning GO:0007612 82 40 0,000 0,07898723 0,09219579 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07898723 0,09215176 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,07898723 0,09210778 ! mismatch repair GO:0006298 58 40 0,000 0,07898723 0,09206383 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07898723 0,09201993 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,07898723 0,09197607 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08088093 0,0941363 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08088093 0,09409148 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08088093 0,09404669 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,08088093 0,09400195 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08088093 0,09395725 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08088093 0,0939126 ! gliogenesis GO:0042063 91 41 0,000 0,08088093 0,09386798 ! feeding behavior GO:0007631 69 41 0,000 0,08088093 0,09382341 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08088093 0,09377888 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,08088093 0,09373439 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08088093 0,09368995 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08088093 0,09364555 ! spermatid differentiation GO:0048515 73 41 0,000 0,08088093 0,09360118 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08088093 0,09355687 ! RNA modification GO:0009451 64 41 0,000 0,08088093 0,09351259 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,08277079 0,09565233 ! ear morphogenesis GO:0042471 64 42 0,000 0,08277079 0,09560711 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,08277079 0,09556192 ! T cell differentiation GO:0030217 93 42 0,000 0,08277079 0,09551678 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,08277079 0,09547168 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,08277079 0,09542663 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,08277079 0,09538162 ! regulation of protein secretion GO:0050708 77 42 0,000 0,08277079 0,09533665 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,08277079 0,09529172 ! cytokinesis GO:0000910 84 42 0,000 0,08277079 0,09524683 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,08277079 0,09520199 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,08465681 0,09732546 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,08465681 0,09727968 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08465681 0,09723394 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08465681 0,09718825 ! regulation of tube size GO:0035150 76 43 0,000 0,08465681 0,0971426 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,08465681 0,09709699 ! glucose transport GO:0015758 66 43 0,000 0,08465681 0,09705143 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08465681 0,09700591 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08465681 0,09696043 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08465681 0,09691499 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08465681 0,0968696 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,08465681 0,09682425 ! segmentation GO:0035282 78 43 0,000 0,08465681 0,09677894 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08465681 0,09673367 ! neuron migration GO:0001764 85 43 0,000 0,08465681 0,09668845 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,08653901 0,09879197 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,08653901 0,09874583 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,08653901 0,09869973 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,08653901 0,09865367 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,08653901 0,09860765 ! hexose transport GO:0008645 68 44 0,000 0,08653901 0,09856168 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,08653901 0,09851576 ! striated muscle contraction GO:0006941 85 44 0,000 0,08653901 0,09846987 ! phagocytosis GO:0006909 105 44 0,000 0,08653901 0,09842403 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,08653901 0,09837823 ! double-strand break repair GO:0006302 85 44 0,000 0,08653901 0,09833247 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,0884174 0,10042013 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,0884174 0,10037347 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,0884174 0,10032685 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,0884174 0,10028027 ! biopolymer methylation GO:0043414 91 45 0,000 0,0884174 0,10023374 ! B cell differentiation GO:0030183 124 45 0,000 0,0884174 0,10018725 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,0884174 0,1001408 ! female gamete generation GO:0007292 71 45 0,000 0,0884174 0,1000944 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,0884174 0,10004803 ! polyol metabolic process GO:0019751 77 45 0,000 0,0884174 0,10000172 ! developmental growth GO:0048589 88 45 0,000 0,0884174 0,09995544 ! maintenance of location in cell GO:0051651 101 45 0,000 0,0884174 0,09990921 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09029197 0,10198025 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09029197 0,10193313 ! glycolysis GO:0006096 71 46 0,000 0,09029197 0,10188605 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,09029197 0,10183901 ! leukocyte migration GO:0050900 75 46 0,000 0,09029197 0,10179201 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,09029197 0,10174506 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,09029197 0,10169815 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09029197 0,10165129 ! pigmentation GO:0043473 103 46 0,000 0,09029197 0,10160446 ! cell growth GO:0016049 90 46 0,000 0,09029197 0,10155768 ! neural tube development GO:0021915 91 47 0,000 0,09216275 0,10361417 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,09216275 0,10356651 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09402972 0,10561592 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09402972 0,10556738 ! mitochondrial transport GO:0006839 94 48 0,000 0,09402972 0,10551889 ! cellular component disassembly GO:0022411 89 48 0,000 0,09402972 0,10547044 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09402972 0,10542204 ! endosome transport GO:0016197 127 48 0,000 0,09402972 0,10537368 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,09402972 0,10532536 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09402972 0,10527709 ! male sex differentiation GO:0046661 93 48 0,000 0,09402972 0,10522887 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09402972 0,10518069 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09402972 0,10513255 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09402972 0,10508445 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09402972 0,1050364 ! methylation GO:0032259 97 48 0,000 0,09402972 0,1049884 ! response to calcium ion GO:0051592 94 49 0,000 0,09589292 0,10701982 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,09589292 0,10697096 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,09589292 0,10692213 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,09589292 0,10687335 ! JNK cascade GO:0007254 106 49 0,000 0,09589292 0,10682462 ! regulation of action potential GO:0001508 102 50 0,000 0,09775233 0,10884637 ! regulation of ion transport GO:0043269 86 50 0,000 0,09775233 0,10879678 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,09775233 0,10874724 ! endocrine system development GO:0035270 109 50 0,000 0,09775233 0,10869774 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,09775233 0,10864829 ! activation of caspase activity GO:0006919 95 50 0,000 0,09775233 0,10859888 ! regulation of ossification GO:0030278 123 50 0,000 0,09775233 0,10854952 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09775233 0,1085002 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09775233 0,10845092 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09775233 0,1084017 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09775233 0,10835251 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,09960797 0,1103593 ! viral infectious cycle GO:0019058 104 51 0,000 0,09960797 0,11030928 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,09960797 0,11025929 ! peptide metabolic process GO:0006518 80 51 0,000 0,09960797 0,11020936 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09960797 0,11015947 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09960797 0,11010962 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,09960797 0,11005982 ! positive regulation of binding GO:0051099 88 52 0,000 0,10145984 0,11205533 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,10145984 0,1120047 ! Notch signaling pathway GO:0007219 111 52 0,000 0,10145984 0,11195411 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,10145984 0,11190356 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,10145984 0,11185307 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,10145984 0,11180261 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,10145984 0,11175221 ! excretion GO:0007588 87 52 0,000 0,10145984 0,11170185 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,10145984 0,11165153 ! histone modification GO:0016570 104 52 0,000 0,10145984 0,11160126 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,10145984 0,11155103 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,10145984 0,11150085 ! amino acid activation GO:0043038 98 52 0,000 0,10145984 0,11145072 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10330796 0,11342982 ! positive regulation of growth GO:0045927 96 53 0,000 0,10330796 0,11337886 ! chromatin remodeling GO:0006338 122 53 0,000 0,10330796 0,11332795 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10330796 0,11327709 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10330796 0,11322627 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,10330796 0,11317549 ! cartilage development GO:0051216 99 53 0,000 0,10330796 0,11312476 ! synapse organization GO:0050808 102 53 0,000 0,10330796 0,11307408 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,10515233 0,11504126 ! regulation of translational initiation GO:0006446 87 54 0,000 0,10515233 0,11498977 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,10515233 0,11493832 ! neuromuscular process GO:0050905 107 54 0,000 0,10515233 0,11488692 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,10515233 0,11483556 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,10515233 0,11478425 ! covalent chromatin modification GO:0016569 115 54 0,000 0,10515233 0,11473298 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,10515233 0,11468176 ! regulation of cell shape GO:0008360 142 54 0,000 0,10515233 0,11463059 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,10515233 0,11457946 ! RNA catabolic process GO:0006401 103 55 0,000 0,10699296 0,11653312 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,10699296 0,11648119 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,10699296 0,11642931 ! cell recognition GO:0008037 98 55 0,000 0,10699296 0,11637747 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,10699296 0,11632568 ! cell maturation GO:0048469 107 55 0,000 0,10699296 0,11627393 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,10699296 0,11622223 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,10882985 0,11816503 ! glucose catabolic process GO:0006007 88 56 0,000 0,10882985 0,11811254 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,10882985 0,11806009 ! regulation of DNA replication GO:0006275 105 56 0,000 0,10882985 0,11800769 ! chloride transport GO:0006821 102 57 0,000 0,11066302 0,11994222 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,11066302 0,11988903 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,11066302 0,11983588 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 105 57 0,000 0,11066302 0,11978279 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11249247 0,12170908 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,11249247 0,1216552 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11249247 0,12160137 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11249247 0,12154759 ! aging GO:0007568 112 58 0,000 0,11249247 0,12149385 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,11249247 0,12144017 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11249247 0,12138653 ! maintenance of location GO:0051235 124 58 0,000 0,11249247 0,12133293 ! nuclear export GO:0051168 110 59 0,000 0,1143182 0,12324773 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1143182 0,12319337 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,11614023 0,12510167 ! regulation of endocytosis GO:0030100 104 60 0,000 0,11614023 0,12504654 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,11614023 0,12499145 ! adult behavior GO:0030534 104 60 0,000 0,11614023 0,12493641 ! kidney development GO:0001822 133 60 0,000 0,11614023 0,12488142 ! regulation of cellular component size GO:0032535 125 61 0,000 0,11795857 0,12678081 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,11795857 0,12672506 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,11795857 0,12666935 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,11795857 0,1266137 ! regulation of heart contraction GO:0008016 123 61 0,000 0,11795857 0,12655809 ! proton transport GO:0015992 117 61 0,000 0,11795857 0,12650254 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,11795857 0,12644703 ! viral reproductive process GO:0022415 132 62 0,000 0,11977321 0,12833594 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,11977321 0,12827968 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,11977321 0,12822347 ! tRNA processing GO:0008033 102 62 0,000 0,11977321 0,1281673 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,11977321 0,12811119 ! regulation of mitosis GO:0007088 112 63 0,000 0,12158417 0,12999131 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,12158417 0,12993444 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12158417 0,12987763 ! hydrogen transport GO:0006818 121 64 0,000 0,12339146 0,13175058 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12339146 0,13169303 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,12339146 0,13163552 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,12519508 0,13350134 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,12519508 0,1334431 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,12519508 0,1333849 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,12519508 0,13332676 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,12519508 0,13326866 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,12699504 0,13512582 ! gonad development GO:0008406 115 66 0,000 0,12699504 0,13506699 ! activation of MAPK activity GO:0000187 124 67 0,000 0,12879135 0,13691787 ! chromosome segregation GO:0007059 127 67 0,000 0,12879135 0,13685831 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,12879135 0,13679881 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,12879135 0,13673936 ! secondary metabolic process GO:0019748 125 67 0,000 0,12879135 0,13667996 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,13058401 0,13852224 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,13058401 0,13846212 ! hexose catabolic process GO:0019320 113 68 0,000 0,13058401 0,13840205 ! extracellular matrix organization GO:0030198 146 68 0,000 0,13058401 0,13834203 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,13058401 0,13828207 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,13058401 0,13822215 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,13058401 0,13816229 ! viral reproduction GO:0016032 142 68 0,000 0,13058401 0,13810248 ! adaptive immune response GO:0002250 126 68 0,000 0,13058401 0,13804272 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,13058401 0,13798301 ! cell projection assembly GO:0030031 138 68 0,000 0,13058401 0,13792336 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13237303 0,13975251 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13237303 0,13969214 ! urogenital system development GO:0001655 149 69 0,000 0,13237303 0,13963183 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13237303 0,13957156 ! developmental maturation GO:0021700 128 69 0,000 0,13237303 0,13951135 ! single fertilization GO:0007338 83 69 0,000 0,13237303 0,13945119 ! cell redox homeostasis GO:0045454 114 70 0,000 0,13415842 0,14127113 ! germ cell development GO:0007281 133 70 0,000 0,13415842 0,14121026 ! activation of immune response GO:0002253 120 70 0,000 0,13415842 0,14114945 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,13415842 0,14108869 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,13594019 0,14290098 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,13594019 0,14283952 ! carbohydrate transport GO:0008643 114 72 0,000 0,13771834 0,1446457 ! actin filament organization GO:0007015 167 72 0,000 0,13771834 0,14458354 ! B cell activation GO:0042113 179 72 0,000 0,13771834 0,14452144 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,13771834 0,14445938 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,13771834 0,14439738 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,13771834 0,14433544 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,13771834 0,14427354 ! humoral immune response GO:0006959 115 73 0,000 0,13949288 0,14606992 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,13949288 0,14600733 ! regulation of immune effector process GO:0002697 156 73 0,000 0,13949288 0,1459448 ! acute inflammatory response GO:0002526 118 74 0,000 0,14126382 0,14773438 ! amino acid transport GO:0006865 148 74 0,000 0,14126382 0,14767117 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,14126382 0,14760801 ! organelle localization GO:0051640 155 74 0,000 0,14126382 0,1475449 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,14303117 0,14932698 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,14303117 0,1492632 ! reproductive structure development GO:0048608 131 75 0,000 0,14303117 0,14919946 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,14303117 0,14913578 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,14303117 0,14907216 ! axon guidance GO:0007411 162 75 0,000 0,14303117 0,14900859 ! rhythmic process GO:0048511 142 75 0,000 0,14303117 0,14894507 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,14479493 0,15071751 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,14479493 0,15065332 ! learning or memory GO:0007611 161 76 0,000 0,14479493 0,15058919 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,14479493 0,15052511 ! regulation of blood pressure GO:0008217 134 76 0,000 0,14479493 0,15046108 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,14479493 0,15039711 ! amine catabolic process GO:0009310 136 77 0,000 0,1465551 0,1521607 ! neurotransmitter transport GO:0006836 142 77 0,000 0,1465551 0,15209606 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,1465551 0,15203147 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,1465551 0,15196694 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,1465551 0,15190247 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,1465551 0,15183805 ! regulation of catabolic process GO:0009894 173 77 0,000 0,1465551 0,15177368 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,14831171 0,15352775 ! antigen processing and presentation GO:0019882 117 78 0,000 0,14831171 0,15346273 ! fertilization GO:0009566 99 78 0,000 0,14831171 0,15339776 ! blood coagulation GO:0007596 151 79 0,000 0,15006475 0,15514523 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,15006475 0,1550796 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,15006475 0,15501403 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,15006475 0,15494851 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,15006475 0,15488305 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,15006475 0,15481764 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,15181422 0,15655642 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,15181422 0,15649036 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,15181422 0,15642436 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,15181422 0,15635841 ! meiosis GO:0007126 143 81 0,000 0,15356015 0,15808995 GO:0051327|M phase of meiotic cell cycle, ! cell-substrate adhesion GO:0031589 189 82 0,000 0,15530253 0,15981638 ! protein import into nucleus GO:0006606 174 82 0,000 0,15530253 0,15974909 ! meiotic cell cycle GO:0051321 144 82 0,000 0,15530253 0,15968186 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,15704138 0,1614018 ! exocytosis GO:0006887 153 83 0,000 0,15704138 0,16133393 ! response to drug GO:0042493 149 83 0,000 0,15704138 0,16126612 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,15704138 0,16119836 ! nuclear import GO:0051170 177 83 0,000 0,15704138 0,16113065 ! inorganic anion transport GO:0015698 156 83 0,000 0,15704138 0,16106301 ! response to metal ion GO:0010038 158 84 0,000 0,15877669 0,16277443 ! T cell activation GO:0042110 189 84 0,000 0,15877669 0,16270615 ! response to nutrient GO:0007584 135 84 0,000 0,15877669 0,16263793 ! digestion GO:0007586 130 84 0,000 0,15877669 0,16256977 ! regulation of ligase activity GO:0051340 147 84 0,000 0,15877669 0,16250166 ! hemostasis GO:0007599 165 85 0,000 0,16050848 0,16420529 ! negative regulation of transport GO:0051051 164 85 0,000 0,16050848 0,16413655 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,16050848 0,16406788 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,16050848 0,16399926 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,16050848 0,1639307 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,16050848 0,16386219 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,16223676 0,16555739 ! regulation of lyase activity GO:0051339 169 86 0,000 0,16223676 0,16548827 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,16396152 0,1671778 ! mitochondrion organization GO:0007005 159 87 0,000 0,16396152 0,16710805 ! alcohol catabolic process GO:0046164 142 87 0,000 0,16396152 0,16703837 ! nucleosome assembly GO:0006334 126 87 0,000 0,16396152 0,16696874 ! cellular respiration GO:0045333 143 88 0,000 0,16568279 0,16865127 ! amine biosynthetic process GO:0009309 146 88 0,000 0,16568279 0,16858103 ! sensory perception of smell GO:0007608 117 88 0,000 0,16568279 0,16851084 ! chromatin assembly GO:0031497 128 88 0,000 0,16568279 0,16844072 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,16568279 0,16837065 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,16740055 0,17004555 ! regulation of DNA binding GO:0051101 167 89 0,000 0,16740055 0,16997488 ! tube morphogenesis GO:0035239 194 89 0,000 0,16740055 0,16990426 ! cellular defense response GO:0006968 123 89 0,000 0,16740055 0,1698337 ! protein localization in nucleus GO:0034504 192 89 0,000 0,16740055 0,1697632 ! regulation of neurological system process GO:0031644 175 89 0,000 0,16740055 0,16969276 ! response to inorganic substance GO:0010035 173 90 0,000 0,16911483 0,17135941 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,16911483 0,17128836 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,16911483 0,17121738 ! response to unfolded protein GO:0006986 139 90 0,000 0,16911483 0,17114645 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,16911483 0,17107558 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,17082563 0,17273469 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,17082563 0,17266322 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,17253295 0,17431679 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,17253295 0,17424473 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,17423681 0,17589278 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,17423681 0,17582013 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,17423681 0,17574753 ! vitamin metabolic process GO:0006766 153 93 0,000 0,17423681 0,175675 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,1759372 0,17731625 ! female pregnancy GO:0007565 166 94 0,000 0,1759372 0,17724313 ! sterol metabolic process GO:0016125 166 94 0,000 0,1759372 0,17717007 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,1759372 0,17709707 ! regulation of defense response GO:0031347 171 95 0,000 0,17763415 0,17873156 ! nucleosome organization GO:0034728 143 95 0,000 0,17763415 0,17865797 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,17763415 0,17858445 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,17763415 0,17851099 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,17763415 0,17843759 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,17763415 0,17836425 ! sex differentiation GO:0007548 171 96 0,000 0,17932764 0,17999073 ! response to protein stimulus GO:0051789 158 96 0,000 0,17932764 0,17991681 ! regulation of T cell activation GO:0050863 175 96 0,000 0,17932764 0,17984295 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,1810177 0,18146337 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,1810177 0,18138894 ! leukocyte differentiation GO:0002521 232 98 0,000 0,18270432 0,18300396 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,18270432 0,18292895 ! mRNA transport GO:0051028 185 100 0,000 0,18606729 0,18621974 ! positive regulation of immune response GO:0050778 175 100 0,000 0,18606729 0,18614349 ! hormone metabolic process GO:0042445 171 100 0,000 0,18606729 0,18606729