pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/605-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 1,184E-07 2,848E-04 ! interphase GO:0051325 213 98 7,000 1,509E-07 1,815E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 3,436E-07 2,756E-04 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 3,000 2,888E-06 1,737E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 7,66E-06 3,686E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,738E-05 6,971E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,775E-05 6,102E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 2,476E-05 7,446E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,525E-05 6,75E-03 ! regulation of chemokine biosynthetic process GO:0045073 12 10 2,000 2,525E-05 6,075E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,588E-05 0,01003486 ! actin filament organization GO:0007015 148 66 4,000 5,057E-05 0,01014025 ! regulation of chemokine production GO:0032642 18 13 2,000 5,938E-05 0,01098926 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 7,291E-05 0,01253076 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 7,523E-05 0,01206759 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 2,000 9,362E-05 0,01407886 ! G1 phase of mitotic cell cycle GO:0000080 35 16 2,000 1,147E-04 0,01623608 ! activation of protein kinase activity GO:0032147 147 79 4,000 1,197E-04 0,01600186 ! signal complex assembly GO:0007172 41 17 2,000 1,387E-04 0,01756159 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,387E-04 0,01668351 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,428E-04 0,01636463 ! response to insulin stimulus GO:0032868 95 46 3,000 1,727E-04 0,01888495 ! regulation of postsynaptic membrane potential GO:0060078 32 19 2,000 1,959E-04 0,02048986 ! G1 phase GO:0051318 40 19 2,000 1,959E-04 0,01963612 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 2,04E-04 0,01963044 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,294E-04 0,02122964 ! actin polymerization or depolymerization GO:0008154 48 20 2,000 2,294E-04 0,02044336 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 3,000 2,583E-04 0,02219489 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,583E-04 0,02142955 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,665E-04 0,02137028 ! response to UV GO:0009411 104 53 3,000 2,998E-04 0,02327065 ! apoptotic nuclear changes GO:0030262 32 22 2,000 3,072E-04 0,02309509 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,517E-04 0,02564031 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 1,000 3,589E-04 0,02539558 ! female meiosis GO:0007143 7 5 1,000 3,589E-04 0,02466999 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,589E-04 0,02398471 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,589E-04 0,02333648 ! skeletal myofibril assembly GO:0014866 10 5 1,000 3,589E-04 0,02272236 ! cardiac muscle fiber development GO:0048739 10 5 1,000 3,589E-04 0,02213974 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,589E-04 0,02158624 ! valine metabolic process GO:0006573 10 5 1,000 3,589E-04 0,02105975 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,589E-04 0,02055833 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,589E-04 0,02008023 ! B cell homeostasis GO:0001782 13 5 1,000 3,589E-04 0,01962386 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 4,001E-04 0,02139375 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 4,001E-04 0,02092867 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 4,001E-04 0,02048338 ! membrane depolarization GO:0051899 39 24 2,000 4,001E-04 0,02005664 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 4,527E-04 0,02222755 ! DNA catabolic process GO:0006308 86 59 3,000 4,531E-04 0,02180141 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 4,832E-04 0,0227934 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 5,095E-04 0,02357225 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 5,146E-04 0,02336255 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 1,000 5,362E-04 0,02388928 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 5,362E-04 0,02345493 ! regulation of interferon-beta production GO:0032648 8 6 1,000 5,362E-04 0,02303609 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! neuron remodeling GO:0016322 15 6 1,000 5,362E-04 0,02263195 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 5,362E-04 0,02224174 ! hyperosmotic response GO:0006972 9 6 1,000 5,362E-04 0,02186476 ! neuron apoptosis GO:0051402 9 6 1,000 5,362E-04 0,02150035 ! interaction with symbiont GO:0051702 13 6 1,000 5,362E-04 0,02114789 ! positive regulation of cytokine production during immune response GO:0002720 9 6 1,000 5,362E-04 0,02080679 ! response to exogenous dsRNA GO:0043330 10 6 1,000 5,362E-04 0,02047652 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 5,362E-04 0,02015658 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,362E-04 0,01984648 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 5,706E-04 0,02080103 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 6,362E-04 0,02284781 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 7,065E-04 0,02499816 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 7,349E-04 0,02562577 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 7,477E-04 0,02569781 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,477E-04 0,02533587 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 7,477E-04 0,02498398 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 7,477E-04 0,02464173 ! centrosome duplication GO:0051298 13 7 1,000 7,477E-04 0,02430874 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 1,000 7,477E-04 0,02398462 ! negative regulation of osteoclast differentiation GO:0045671 10 7 1,000 7,477E-04 0,02366903 ! negative regulation of kinase activity GO:0033673 131 68 3,000 7,772E-04 0,02428447 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 7,772E-04 0,02397313 ! neurotransmitter secretion GO:0007269 48 30 2,000 7,815E-04 0,02380241 ! regulation of B cell activation GO:0050864 50 30 2,000 7,815E-04 0,02350488 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 8,212E-04 0,0243913 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 8,615E-04 0,0252762 GO:0043433|negative regulation of transcription factor activity, ! response to mechanical stimulus GO:0009612 57 32 2,000 9,464E-04 0,02743306 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 9,636E-04 0,02759935 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 9,636E-04 0,02727465 ! negative regulation of transferase activity GO:0051348 140 72 3,000 9,636E-04 0,02695751 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,929E-04 0,02745894 ! regulation of interferon-alpha production GO:0032647 11 8 1,000 9,929E-04 0,02714691 ! succinate metabolic process GO:0006105 14 8 1,000 9,929E-04 0,02684188 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,929E-04 0,02654364 ! negative regulation of muscle cell differentiation GO:0051148 15 8 1,000 9,929E-04 0,02625195 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 9,929E-04 0,02596661 GO:0006559|L-phenylalanine catabolic process, ! Schwann cell differentiation GO:0014037 19 8 1,000 9,929E-04 0,0256874 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 1,000 9,929E-04 0,02541412 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 9,929E-04 0,02514661 ! negative regulation of protein transport GO:0051224 69 33 2,000 1,036E-03 0,0259746 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,068E-03 0,02648177 GO:0090046|regulation of transcription regulator activity, ! negative regulation of secretion GO:0051048 63 35 2,000 1,232E-03 0,0302539 ! calcium-mediated signaling GO:0019722 62 35 2,000 1,232E-03 0,0299483 ! positive regulation of ligase activity GO:0051351 124 77 3,000 1,238E-03 0,02979019 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 1,238E-03 0,02949524 ! elastic fiber assembly GO:0048251 15 9 1,000 1,272E-03 0,02999289 ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 1,272E-03 0,02970169 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,272E-03 0,0294161 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,272E-03 0,02913595 GO:0006600|creatine metabolic process, ! regulation of type I interferon production GO:0032479 12 9 1,000 1,272E-03 0,02886108 ! Rac protein signal transduction GO:0016601 17 9 1,000 1,272E-03 0,02859135 ! receptor clustering GO:0043113 18 9 1,000 1,272E-03 0,02832662 ! negative regulation of cytokine secretion GO:0050710 14 9 1,000 1,272E-03 0,02806674 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,272E-03 0,02781159 ! mitochondrion localization GO:0051646 15 9 1,000 1,272E-03 0,02756103 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,338E-03 0,02875112 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,362E-03 0,02899751 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,45E-03 0,03060329 ! nucleus organization GO:0006997 67 38 2,000 1,567E-03 0,03279205 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 1,567E-03 0,03250936 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,583E-03 0,03255475 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 1,000 1,583E-03 0,03227886 ! response to dsRNA GO:0043331 20 10 1,000 1,583E-03 0,03200761 ! oocyte development GO:0048599 17 10 1,000 1,583E-03 0,03174088 ! localization within membrane GO:0051668 20 10 1,000 1,583E-03 0,03147856 ! negative regulation of transport GO:0051051 153 84 3,000 1,709E-03 0,03369449 ! regulation of ligase activity GO:0051340 142 84 3,000 1,709E-03 0,03342055 ! positive regulation of cell activation GO:0050867 145 85 3,000 1,785E-03 0,03462597 GO:0002696|positive regulation of leukocyte activation, ! negative regulation of binding GO:0051100 72 40 2,000 1,819E-03 0,03502146 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,927E-03 0,0368004 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,927E-03 0,03651063 ! positive regulation of T cell mediated immunity GO:0002711 24 11 1,000 1,927E-03 0,03622539 ! DNA methylation GO:0006306 19 11 1,000 1,927E-03 0,03594457 GO:0006305|DNA alkylation, ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 1,927E-03 0,03566808 ! oocyte differentiation GO:0009994 18 11 1,000 1,927E-03 0,0353958 ! positive regulation of JNK cascade GO:0046330 23 11 1,000 1,927E-03 0,03512765 ! lamellipodium assembly GO:0030032 20 11 1,000 1,927E-03 0,03486353 ! gliogenesis GO:0042063 88 41 2,000 1,954E-03 0,03509291 ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,954E-03 0,03483296 ! keratinocyte differentiation GO:0030216 62 41 2,000 1,954E-03 0,03457683 ! regulation of DNA binding GO:0051101 155 88 3,000 2,027E-03 0,03559162 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,096E-03 0,03653506 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,243E-03 0,03882069 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,303E-03 0,03958674 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,303E-03 0,03930598 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 2,303E-03 0,03902918 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 1,000 2,303E-03 0,03875625 ! tyrosine metabolic process GO:0006570 16 12 1,000 2,303E-03 0,03848711 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 1,000 2,303E-03 0,03822168 ! cranial nerve development GO:0021545 20 12 1,000 2,303E-03 0,03795989 ! T cell homeostasis GO:0043029 25 12 1,000 2,303E-03 0,03770166 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,303E-03 0,03744692 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,303E-03 0,03719559 GO:0042130|negative regulation of T cell proliferation, ! maintenance of location in cell GO:0051651 97 44 2,000 2,396E-03 0,03843588 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 2,479E-03 0,03949969 GO:0010498|proteasomal protein catabolic process, ! transcription initiation GO:0006352 153 94 3,000 2,577E-03 0,04079312 ! regulation of T cell activation GO:0050863 158 94 3,000 2,577E-03 0,0405265 ! endocrine pancreas development GO:0031018 22 13 1,000 2,711E-03 0,04236254 ! regulation of cytokine production during immune response GO:0002718 23 13 1,000 2,711E-03 0,04208923 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,711E-03 0,04181943 ! positive regulation of protein polymerization GO:0032273 25 13 1,000 2,711E-03 0,04155307 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,711E-03 0,04129007 ! epidermal cell differentiation GO:0009913 68 46 2,000 2,722E-03 0,0411953 ! cellular component disassembly GO:0022411 86 48 2,000 3,075E-03 0,04623439 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,151E-03 0,04708675 ! negative regulation of protein secretion GO:0050709 28 14 1,000 3,151E-03 0,0467961 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,151E-03 0,046509 ! cell cycle arrest GO:0007050 213 100 3,000 3,222E-03 0,04727543 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 3,621E-03 0,05280372 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 3,621E-03 0,05248563 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,621E-03 0,05217134 ! cell killing GO:0001906 29 15 1,000 3,621E-03 0,0518608 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,621E-03 0,05155393 ! cell maturation GO:0048469 100 53 2,000 4,073E-03 0,05765199 ! response to osmotic stress GO:0006970 25 16 1,000 4,122E-03 0,05799908 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,122E-03 0,05766188 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,122E-03 0,05732857 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 4,122E-03 0,0569991 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 2,000 4,294E-03 0,05903853 ! positive regulation of protein complex assembly GO:0031334 32 17 1,000 4,653E-03 0,06361212 ! gene silencing by RNA GO:0031047 36 17 1,000 4,653E-03 0,06325273 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 4,653E-03 0,06289738 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,653E-03 0,06254599 ! cardiac muscle tissue development GO:0048738 31 17 1,000 4,653E-03 0,06219852 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,653E-03 0,06185488 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,653E-03 0,06151502 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,653E-03 0,06117887 ! skeletal muscle fiber development GO:0048741 111 56 2,000 4,757E-03 0,06220175 ! muscle fiber development GO:0048747 112 57 2,000 4,999E-03 0,0650157 ! maintenance of location GO:0051235 118 57 2,000 4,999E-03 0,06466616 ! neuron maturation GO:0042551 42 18 1,000 5,214E-03 0,06708755 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,214E-03 0,0667307 ! memory GO:0007613 31 18 1,000 5,214E-03 0,06637763 ! centrosome cycle GO:0007098 25 18 1,000 5,214E-03 0,06602827 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 5,214E-03 0,06568257 ! aromatic compound catabolic process GO:0019439 27 18 1,000 5,214E-03 0,06534048 ! nerve development GO:0021675 28 18 1,000 5,214E-03 0,06500192 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 5,506E-03 0,06828043 ! regulation of neurotransmitter levels GO:0001505 97 60 2,000 5,77E-03 0,0711918 ! lipid phosphorylation GO:0046834 35 19 1,000 5,805E-03 0,07125436 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,805E-03 0,07089266 ! response to lipopolysaccharide GO:0032496 30 19 1,000 5,805E-03 0,07053462 ! peptide cross-linking GO:0018149 37 19 1,000 5,805E-03 0,07018017 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 5,805E-03 0,06982927 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 1,000 5,805E-03 0,06948186 ! regulation of homeostatic process GO:0032844 134 62 2,000 6,321E-03 0,07528991 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,424E-03 0,07613934 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,424E-03 0,07576611 ! response to alkaloid GO:0043279 38 20 1,000 6,424E-03 0,07539652 ! pancreas development GO:0031016 35 20 1,000 6,424E-03 0,07503051 ! cellular response to starvation GO:0009267 33 20 1,000 6,424E-03 0,07466805 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 6,424E-03 0,07430907 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 6,424E-03 0,07395352 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 6,424E-03 0,07360136 ! actin filament-based movement GO:0030048 43 20 1,000 6,424E-03 0,07325254 ! negative regulation of T cell activation GO:0050868 40 20 1,000 6,424E-03 0,07290701 ! negative regulation of coagulation GO:0050819 29 20 1,000 6,424E-03 0,07256472 ! detection of external stimulus GO:0009581 91 63 2,000 6,608E-03 0,07429431 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 6,608E-03 0,07394876 ! inactivation of MAPK activity GO:0000188 39 21 1,000 7,072E-03 0,07877675 ! smooth muscle contraction GO:0006939 46 21 1,000 7,072E-03 0,07841372 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 7,072E-03 0,07805403 ! oogenesis GO:0048477 36 21 1,000 7,072E-03 0,07769762 ! DNA modification GO:0006304 34 21 1,000 7,072E-03 0,07734445 ! detection of biotic stimulus GO:0009595 29 21 1,000 7,072E-03 0,07699447 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 7,205E-03 0,07808609 ! developmental maturation GO:0021700 116 66 2,000 7,515E-03 0,08108094 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 7,749E-03 0,0832297 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 7,749E-03 0,08285979 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,749E-03 0,08249315 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 7,749E-03 0,08212974 ! positive regulation of adaptive immune response GO:0002821 39 22 1,000 7,749E-03 0,08176953 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,749E-03 0,08141245 ! regulation of cytokine secretion GO:0050707 37 22 1,000 7,749E-03 0,08105849 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,749E-03 0,08070758 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 7,749E-03 0,08035971 ! protein stabilization GO:0050821 39 22 1,000 7,749E-03 0,08001481 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 7,833E-03 0,08053724 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 7,833E-03 0,08019453 ! positive regulation of T cell activation GO:0050870 109 67 2,000 7,833E-03 0,07985472 ! negative regulation of ligase activity GO:0051352 112 68 2,000 8,158E-03 0,08282369 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 8,158E-03 0,08247569 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 8,453E-03 0,08509805 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 8,453E-03 0,08474348 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 8,453E-03 0,08439185 ! visual behavior GO:0007632 42 23 1,000 8,453E-03 0,08404312 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,453E-03 0,08369726 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 8,453E-03 0,08335424 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,453E-03 0,08301402 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 8,453E-03 0,08267656 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 9,185E-03 0,08947313 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 1,000 9,185E-03 0,08911235 ! leukocyte homeostasis GO:0001776 44 24 1,000 9,185E-03 0,08875447 ! acute inflammatory response GO:0002526 113 72 2,000 9,54E-03 0,09181397 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 9,945E-03 0,09532622 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 9,945E-03 0,09494794 ! receptor metabolic process GO:0043112 46 25 1,000 9,945E-03 0,09457266 ! response to starvation GO:0042594 42 25 1,000 9,945E-03 0,09420032 ! interaction with host GO:0051701 62 25 1,000 9,945E-03 0,09383091 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,945E-03 0,09346438 ! neurotransmitter transport GO:0006836 123 74 2,000 0,01027891 0,09622981 ! exocytosis GO:0006887 133 74 2,000 0,01027891 0,09585682 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 0,01073094 0,09968588 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01073094 0,09930247 ! microtubule organizing center organization GO:0031023 39 26 1,000 0,01073094 0,098922 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 0,01073094 0,09854444 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01073094 0,09816974 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01073094 0,09779789 ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 0,01073094 0,09742884 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01154377 0,10441468 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01154377 0,10402361 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01154377 0,10363546 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,01185379 0,10602316 ! protein oligomerization GO:0051259 139 78 2,000 0,01185379 0,10563048 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 0,01226795 0,10891765 ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,01226795 0,10851722 ! protein import into nucleus GO:0006606 158 80 2,000 0,01269033 0,11184223 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 0,01312095 0,11521539 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 2,000 0,01312095 0,11479643 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01324772 0,11548554 ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01324772 0,11506863 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01324772 0,11465471 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01324772 0,11424376 ! regulation of coagulation GO:0050818 46 29 1,000 0,01324772 0,11383575 ! cholesterol metabolic process GO:0008203 136 82 2,000 0,01355985 0,11610323 ! acute-phase response GO:0006953 49 30 1,000 0,01413816 0,12062557 ! myofibril assembly GO:0030239 47 30 1,000 0,01413816 0,12019933 GO:0055002|striated muscle cell development, ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01413816 0,1197761 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01413816 0,11935583 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,01446254 0,12166741 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01505379 0,1262001 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,01505379 0,12576191 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,01505379 0,12532675 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01505379 0,12489458 ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,01505379 0,12446539 ! mitochondrion organization GO:0007005 148 86 2,000 0,01539855 0,12687981 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01587908 0,13039274 ! regulation of protein transport GO:0051223 154 87 2,000 0,01587908 0,12994923 GO:0070201|regulation of establishment of protein localization, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,01599429 0,13044835 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01599429 0,13000764 ! muscle cell development GO:0055001 49 32 1,000 0,01599429 0,12956991 ! negative regulation of MAP kinase activity GO:0043407 69 32 1,000 0,01599429 0,12913511 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01599429 0,12870322 ! gene silencing GO:0016458 65 32 1,000 0,01599429 0,12827421 ! regulation of neurological system process GO:0031644 148 88 2,000 0,01636799 0,13083519 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01686529 0,13436388 ! sterol metabolic process GO:0016125 152 91 2,000 0,0178851 0,14201829 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01794854 0,14205328 ! glial cell differentiation GO:0010001 63 34 1,000 0,01794854 0,14158753 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01794854 0,14112483 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01893858 0,14842417 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01893858 0,14794227 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01896165 0,14764314 ! cytokine production GO:0001816 59 35 1,000 0,01896165 0,14716687 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01999831 0,15471364 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01999831 0,15421777 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01999831 0,15372506 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01999831 0,15323549 ! positive regulation of immune response GO:0050778 156 96 2,000 0,02058207 0,1572078 ! detection of stimulus GO:0051606 151 96 2,000 0,02058207 0,15671031 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,02105822 0,15982986 ! actomyosin structure organization GO:0031032 62 37 1,000 0,02105822 0,15932725 ! regulation of protein stability GO:0031647 73 37 1,000 0,02105822 0,1588278 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,02114679 0,15899743 ! regulation of protein localization GO:0032880 176 97 2,000 0,02114679 0,15850211 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,02214104 0,16543896 GO:0006956|complement activation, ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02230159 0,16612266 GO:0060538|skeletal muscle organ development, ! ear morphogenesis GO:0042471 60 39 1,000 0,02324648 0,17262661 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,02324648 0,17209545 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02437421 0,17989066 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02437421 0,17934053 ! maintenance of protein location GO:0045185 91 40 1,000 0,02437421 0,17879376 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02552394 0,18665838 ! female gamete generation GO:0007292 61 41 1,000 0,02552394 0,18609275 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02669536 0,19404545 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,02669536 0,19346098 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,02669536 0,19288001 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02669536 0,19230253 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,02669536 0,19172849 ! regulation of protein secretion GO:0050708 71 42 1,000 0,02669536 0,19115787 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02788817 0,19910666 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02788817 0,19851759 ! striated muscle contraction GO:0006941 77 43 1,000 0,02788817 0,19793199 ! biopolymer methylation GO:0043414 84 44 1,000 0,02910207 0,20593998 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02910207 0,20533605 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02910207 0,20473565 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02985446 0,20941643 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02985446 0,20880766 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02985446 0,20820242 ! neuron fate determination GO:0048664 7 5 0,000 0,02985446 0,20760068 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02985446 0,2070024 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02985446 0,20640757 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02985446 0,20581614 ! polyol transport GO:0015791 12 5 0,000 0,02985446 0,2052281 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02985446 0,2046434 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02985446 0,20406203 ! response to superoxide GO:0000303 10 5 0,000 0,02985446 0,20348395 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02985446 0,20290914 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02985446 0,20233756 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02985446 0,2017692 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02985446 0,20120402 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02985446 0,20064199 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02985446 0,2000831 ! cobalt ion transport GO:0006824 11 5 0,000 0,02985446 0,19952732 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02985446 0,19897461 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02985446 0,19842496 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02985446 0,19787833 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02985446 0,19733471 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02985446 0,19679407 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02985446 0,19625638 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02985446 0,19572162 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02985446 0,19518977 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02985446 0,1946608 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02985446 0,19413469 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02985446 0,19361141 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02985446 0,19309095 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02985446 0,19257328 ! negative chemotaxis GO:0050919 14 5 0,000 0,02985446 0,19205838 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02985446 0,19154622 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02985446 0,19103679 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02985446 0,19053006 ! behavioral response to pain GO:0048266 9 5 0,000 0,02985446 0,19002602 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02985446 0,18952463 ! Notch receptor processing GO:0007220 8 5 0,000 0,02985446 0,18902588 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02985446 0,18852975 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02985446 0,18803621 ! micturition GO:0060073 9 5 0,000 0,02985446 0,18754526 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02985446 0,18705686 ! copulation GO:0007620 9 5 0,000 0,02985446 0,186571 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02985446 0,18608765 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02985446 0,18560681 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02985446 0,18512844 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02985446 0,18465253 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02985446 0,18417906 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02985446 0,18370802 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02985446 0,18323937 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02985446 0,18277311 ! grooming behavior GO:0007625 6 5 0,000 0,02985446 0,18230922 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02985446 0,18184768 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02985446 0,18138847 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02985446 0,18093157 ! response to protozoan GO:0001562 10 5 0,000 0,02985446 0,18047697 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02985446 0,18002465 ! lymph vessel development GO:0001945 10 5 0,000 0,02985446 0,17957459 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02985446 0,17912677 ! endochondral ossification GO:0001958 16 5 0,000 0,02985446 0,17868118 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02985446 0,1782378 ! parathyroid gland development GO:0060017 13 5 0,000 0,02985446 0,17779662 ! anagen GO:0042640 6 5 0,000 0,02985446 0,17735762 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02985446 0,17692077 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02985446 0,17648608 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02985446 0,17605352 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02985446 0,17562307 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02985446 0,17519472 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02985446 0,17476845 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02985446 0,17434426 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02985446 0,17392212 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02985446 0,17350201 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02985446 0,17308394 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02985446 0,17266787 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02985446 0,1722538 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02985446 0,17184171 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02985446 0,17143159 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02985446 0,17102341 ! histidine catabolic process GO:0006548 6 5 0,000 0,02985446 0,17061718 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02985446 0,17021288 ! microvillus organization GO:0032528 7 5 0,000 0,02985446 0,16981048 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02985446 0,16940999 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02985446 0,16901137 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02985446 0,16861463 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02985446 0,16821975 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02985446 0,16782672 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02985446 0,16743551 ! polyol catabolic process GO:0046174 7 5 0,000 0,02985446 0,16704613 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02985446 0,16665855 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02985446 0,16627276 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02985446 0,16588876 ! muscle cell migration GO:0014812 8 5 0,000 0,02985446 0,16550653 ! mitochondrial fission GO:0000266 8 5 0,000 0,02985446 0,16512606 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02985446 0,16474733 ! mRNA transcription GO:0009299 9 5 0,000 0,02985446 0,16437033 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02985446 0,16399506 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02985446 0,16362149 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02985446 0,16324962 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02985446 0,16287944 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02985446 0,16251094 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02985446 0,1621441 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02985446 0,16177891 ! response to food GO:0032094 6 5 0,000 0,02985446 0,16141536 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02985446 0,16105344 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02985446 0,16069314 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02985446 0,16033445 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02985446 0,15997736 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02985446 0,15962185 ! forebrain neuron development GO:0021884 13 5 0,000 0,02985446 0,15926792 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02985446 0,15891556 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02985446 0,15856476 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02985446 0,15821549 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02985446 0,15786777 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02985446 0,15752157 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02985446 0,15717688 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02985446 0,1568337 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02985446 0,15649201 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02985446 0,15615181 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02985446 0,15581309 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02985446 0,15547583 ! basic amino acid transport GO:0015802 11 5 0,000 0,02985446 0,15514003 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02985446 0,15480568 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02985446 0,15447276 ! depyrimidination GO:0045008 10 5 0,000 0,02985446 0,15414127 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02985446 0,15381121 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02985446 0,15348255 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02985446 0,1531553 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02985446 0,15282943 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02985446 0,15250496 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02985446 0,15218185 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02985446 0,15186011 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02985446 0,15153973 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02985446 0,1512207 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02985446 0,15090301 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02985446 0,15058665 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02985446 0,15027162 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02985446 0,1499579 ! response to arsenic GO:0046685 10 5 0,000 0,02985446 0,14964549 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02985446 0,14933437 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02985446 0,14902455 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02985446 0,14871601 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02985446 0,14840875 ! response to cadmium ion GO:0046686 7 5 0,000 0,02985446 0,14810275 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02985446 0,14779801 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02985446 0,14749453 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02985446 0,14719228 ! decidualization GO:0046697 11 5 0,000 0,02985446 0,14689128 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02985446 0,1465915 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02985446 0,14629294 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02985446 0,1459956 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02985446 0,14569946 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02985446 0,14540452 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02985446 0,14511078 ! neural tube patterning GO:0021532 7 5 0,000 0,02985446 0,14481821 ! embryonic cleavage GO:0040016 6 5 0,000 0,02985446 0,14452683 ! peroxisome fission GO:0016559 5 5 0,000 0,02985446 0,14423661 ! histone demethylation GO:0016577 10 5 0,000 0,02985446 0,14394756 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02985446 0,14365967 ! mitotic recombination GO:0006312 9 5 0,000 0,02985446 0,14337292 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02985446 0,14308732 ! metaphase plate congression GO:0051310 7 5 0,000 0,02985446 0,14280285 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02985446 0,14251951 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02985446 0,1422373 ! enteric nervous system development GO:0048484 8 5 0,000 0,02985446 0,14195619 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02985446 0,1416762 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02985446 0,14139731 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02985446 0,14111952 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02985446 0,14084281 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02985446 0,14056719 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02985446 0,14029264 ! plasminogen activation GO:0031639 5 5 0,000 0,02985446 0,14001917 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02985446 0,13974676 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02985446 0,13947541 ! metaphase GO:0051323 8 5 0,000 0,02985446 0,1392051 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02985446 0,13893585 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02985446 0,13866763 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02985446 0,13840045 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02985446 0,1381343 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02985446 0,13786916 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02985446 0,13760505 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02985446 0,13734194 ! response to redox state GO:0051775 5 5 0,000 0,02985446 0,13707984 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02985446 0,13681873 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02985446 0,13655862 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02985446 0,1362995 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02985446 0,13604135 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02985446 0,13578419 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02985446 0,13552799 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02985446 0,13527276 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02985446 0,13501849 ! striatum development GO:0021756 9 5 0,000 0,02985446 0,13476517 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02985446 0,1345128 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02985446 0,13426137 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02985446 0,13401088 ! glial cell migration GO:0008347 11 5 0,000 0,02985446 0,13376133 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02985446 0,1335127 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02985446 0,133265 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02985446 0,13301821 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02985446 0,13277234 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02985446 0,13252737 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02985446 0,1322833 ! neuroprotection GO:0043526 6 5 0,000 0,02985446 0,13204014 ! neural plate development GO:0001840 8 5 0,000 0,02985446 0,13179786 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02985446 0,13155647 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02985446 0,13131597 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02985446 0,13107634 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02985446 0,13083758 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02985446 0,1305997 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02985446 0,13036268 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02985446 0,13012651 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02985446 0,1298912 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02985446 0,12965674 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02985446 0,12942312 ! spindle assembly GO:0051225 6 5 0,000 0,02985446 0,12919035 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02985446 0,12895841 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02985446 0,1287273 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02985446 0,12849702 ! drug metabolic process GO:0017144 6 5 0,000 0,02985446 0,12826756 ! stem cell division GO:0017145 11 5 0,000 0,02985446 0,12803892 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02985446 0,12781109 ! organ regeneration GO:0031100 7 5 0,000 0,02985446 0,12758407 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02985446 0,12735786 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02985446 0,12713245 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02985446 0,12690783 ! regulation of actin filament polymerization GO:0030833 87 45 1,000 0,03033677 0,12873064 ! glycolysis GO:0006096 65 45 1,000 0,03033677 0,128504 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,03033677 0,12827816 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03033677 0,12805311 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,03033677 0,12782885 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,03159197 0,13288511 ! pigmentation GO:0043473 100 46 1,000 0,03159197 0,1326532 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03159197 0,13242209 ! endosome transport GO:0016197 108 47 1,000 0,03286738 0,13752856 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03286738 0,1372898 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,03286738 0,13705186 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,03286738 0,13681475 ! methylation GO:0032259 90 47 1,000 0,03286738 0,13657845 ! protein homooligomerization GO:0051260 76 47 1,000 0,03286738 0,13634297 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,03416272 0,14147247 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03416272 0,14122939 ! activation of caspase activity GO:0006919 84 48 1,000 0,03416272 0,14098715 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,0354777 0,14616327 ! endocrine system development GO:0035270 104 49 1,000 0,0354777 0,14591341 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,0354777 0,14566442 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0354777 0,14541627 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03571812 0,14615272 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03571812 0,14590458 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03571812 0,14565728 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03571812 0,14541082 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03571812 0,1451652 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03571812 0,1449204 ! sleep GO:0030431 13 6 0,000 0,03571812 0,14467643 ! response to oxygen radical GO:0000305 11 6 0,000 0,03571812 0,14443327 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03571812 0,14419093 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03571812 0,14394941 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03571812 0,14370869 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03571812 0,14346878 ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03571812 0,14322966 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03571812 0,14299134 ! forebrain regionalization GO:0021871 8 6 0,000 0,03571812 0,14275382 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03571812 0,14251708 ! male meiosis GO:0007140 7 6 0,000 0,03571812 0,14228112 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03571812 0,14204595 ! response to zinc ion GO:0010043 9 6 0,000 0,03571812 0,14181155 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03571812 0,14157792 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03571812 0,14134506 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03571812 0,14111297 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03571812 0,14088163 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03571812 0,14065106 ! malate metabolic process GO:0006108 11 6 0,000 0,03571812 0,14042124 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03571812 0,14019216 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03571812 0,13996384 ! protein refolding GO:0042026 15 6 0,000 0,03571812 0,13973625 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03571812 0,13950941 ! opsonization GO:0008228 8 6 0,000 0,03571812 0,1392833 ! mating behavior GO:0007617 7 6 0,000 0,03571812 0,13905792 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03571812 0,13883327 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03571812 0,13860935 ! equilibrioception GO:0050957 14 6 0,000 0,03571812 0,13838615 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03571812 0,13816366 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03571812 0,13794189 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03571812 0,13772083 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03571812 0,13750047 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03571812 0,13728083 ! toxin metabolic process GO:0009404 11 6 0,000 0,03571812 0,13706188 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03571812 0,13684363 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03571812 0,13662607 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03571812 0,1364092 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03571812 0,13619302 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03571812 0,13597753 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03571812 0,13576271 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03571812 0,13554858 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03571812 0,13533511 ! thymic T cell selection GO:0045061 12 6 0,000 0,03571812 0,13512232 ! protein lipoylation GO:0009249 10 6 0,000 0,03571812 0,1349102 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03571812 0,13469874 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03571812 0,13448794 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03571812 0,13427781 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03571812 0,13406833 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03571812 0,1338595 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03571812 0,13365132 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03571812 0,13344378 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03571812 0,13323689 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03571812 0,13303065 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03571812 0,13282503 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03571812 0,13262006 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03571812 0,13241571 ! urea metabolic process GO:0019627 7 6 0,000 0,03571812 0,13221199 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03571812 0,1320089 ! neutrophil activation GO:0042119 8 6 0,000 0,03571812 0,13180644 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03571812 0,13160459 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03571812 0,13140336 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03571812 0,13120274 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03571812 0,13100274 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03571812 0,13080334 ! nucleoside salvage GO:0043174 9 6 0,000 0,03571812 0,13060455 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03571812 0,13040637 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03571812 0,13020878 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03571812 0,1300118 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03571812 0,1298154 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03571812 0,1296196 ! carnitine transport GO:0015879 10 6 0,000 0,03571812 0,12942439 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03571812 0,12922977 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03571812 0,12903573 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03571812 0,12884227 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03571812 0,1286494 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03571812 0,1284571 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03571812 0,12826537 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03571812 0,12807421 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03571812 0,12788363 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03571812 0,12769361 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03571812 0,12750415 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03571812 0,12731525 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03571812 0,12712692 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03571812 0,12693914 ! neural nucleus development GO:0048857 14 6 0,000 0,03571812 0,12675191 ! response to UV-C GO:0010225 11 6 0,000 0,03571812 0,12656524 ! astrocyte development GO:0014002 15 6 0,000 0,03571812 0,12637911 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03571812 0,12619353 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03571812 0,1260085 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03571812 0,12582401 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03571812 0,12564005 ! response to copper ion GO:0046688 10 6 0,000 0,03571812 0,12545664 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03571812 0,12527376 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03571812 0,12509141 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03571812 0,12490959 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03571812 0,1247283 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03571812 0,12454753 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03571812 0,12436729 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03571812 0,12418757 ! hair follicle maturation GO:0048820 7 6 0,000 0,03571812 0,12400836 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03571812 0,12382968 ! Schwann cell development GO:0014044 15 6 0,000 0,03571812 0,12365151 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03571812 0,12347385 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03571812 0,1232967 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03571812 0,12312005 ! subpallium development GO:0021544 10 6 0,000 0,03571812 0,12294392 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03571812 0,12276828 ! histone ubiquitination GO:0016574 8 6 0,000 0,03571812 0,12259315 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03571812 0,12241851 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03571812 0,12224438 ! G2 phase GO:0051319 16 6 0,000 0,03571812 0,12207073 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03571812 0,12189758 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03571812 0,12172492 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03571812 0,12155275 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03571812 0,12138107 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03571812 0,12120987 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03571812 0,12103915 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03571812 0,12086891 ! receptor internalization GO:0031623 10 6 0,000 0,03571812 0,12069915 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03571812 0,12052987 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03571812 0,12036106 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03571812 0,12019272 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03571812 0,12002486 ! protein deubiquitination GO:0016579 14 6 0,000 0,03571812 0,11985746 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03571812 0,11969052 ! protein destabilization GO:0031648 9 6 0,000 0,03571812 0,11952406 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03571812 0,11935805 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03571812 0,11919251 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03571812 0,11902742 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03571812 0,11886279 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03571812 0,11869861 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03571812 0,11853489 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03571812 0,11837162 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03571812 0,1182088 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03571812 0,11804642 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03571812 0,11788449 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03571812 0,11772301 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03571812 0,11756197 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03571812 0,11740136 ! catecholamine transport GO:0051937 9 6 0,000 0,03571812 0,1172412 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03571812 0,11708147 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03571812 0,11692217 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03571812 0,11676331 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03571812 0,11660488 ! maternal placenta development GO:0001893 12 6 0,000 0,03571812 0,11644688 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03571812 0,11628931 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03571812 0,11613216 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03571812 0,11597543 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03571812 0,11581913 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03571812 0,11566325 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03571812 0,11550779 ! regulation of ossification GO:0030278 117 50 1,000 0,03681204 0,11888559 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03681204 0,11872623 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03681204 0,11856729 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03681204 0,11840878 ! positive regulation of binding GO:0051099 78 51 1,000 0,03816546 0,12259825 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03816546 0,12243479 ! excretion GO:0007588 83 51 1,000 0,03816546 0,12227176 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03816546 0,12210917 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03816546 0,121947 ! positive regulation of growth GO:0045927 90 52 1,000 0,03953768 0,12616401 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,04092843 0,13042889 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,04092843 0,13025636 ! regulation of protein polymerization GO:0032271 103 53 1,000 0,04092843 0,13008429 ! tRNA transcription GO:0009304 14 7 0,000 0,04154653 0,13187461 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04154653 0,13170086 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04154653 0,13152757 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04154653 0,13135474 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04154653 0,13118236 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04154653 0,13101043 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04154653 0,13083895 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04154653 0,13066792 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04154653 0,13049733 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04154653 0,13032719 ! prostate gland development GO:0030850 13 7 0,000 0,04154653 0,13015749 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04154653 0,12998824 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04154653 0,12981942 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04154653 0,12965104 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04154653 0,1294831 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04154653 0,1293156 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04154653 0,12914852 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04154653 0,12898188 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04154653 0,12881566 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04154653 0,12864988 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04154653 0,12848452 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04154653 0,12831958 ! glycolipid transport GO:0046836 10 7 0,000 0,04154653 0,12815507 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04154653 0,12799098 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04154653 0,12782731 ! neuron adhesion GO:0007158 12 7 0,000 0,04154653 0,12766406 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,04154653 0,12750122 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04154653 0,1273388 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04154653 0,12717679 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04154653 0,12701519 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04154653 0,126854 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04154653 0,12669323 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04154653 0,12653285 ! mRNA stabilization GO:0048255 18 7 0,000 0,04154653 0,12637289 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04154653 0,12621333 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04154653 0,12605417 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04154653 0,12589541 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04154653 0,12573705 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04154653 0,12557909 ! lipoprotein transport GO:0042953 14 7 0,000 0,04154653 0,12542152 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04154653 0,12526435 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04154653 0,12510758 ! rhythmic behavior GO:0007622 15 7 0,000 0,04154653 0,12495119 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04154653 0,1247952 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04154653 0,12463959 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04154653 0,12448438 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04154653 0,12432955 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04154653 0,1241751 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04154653 0,12402104 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04154653 0,12386735 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04154653 0,12371405 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04154653 0,12356113 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04154653 0,12340859 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04154653 0,12325642 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04154653 0,12310462 ! spinal cord patterning GO:0021511 13 7 0,000 0,04154653 0,1229532 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04154653 0,12280216 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04154653 0,12265148 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04154653 0,12250117 ! adrenal gland development GO:0030325 17 7 0,000 0,04154653 0,12235123 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04154653 0,12220166 ! ovulation GO:0030728 9 7 0,000 0,04154653 0,12205245 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04154653 0,1219036 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04154653 0,12175512 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04154653 0,121607 ! microtubule nucleation GO:0007020 20 7 0,000 0,04154653 0,12145924 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04154653 0,12131184 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04154653 0,12116479 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04154653 0,12101811 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04154653 0,12087177 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04154653 0,12072579 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04154653 0,12058016 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04154653 0,12043489 ! galactose metabolic process GO:0006012 13 7 0,000 0,04154653 0,12028996 ! vesicle fusion GO:0006906 17 7 0,000 0,04154653 0,12014538 ! response to dietary excess GO:0002021 8 7 0,000 0,04154653 0,12000115 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04154653 0,11985726 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04154653 0,11971372 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04154653 0,11957052 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04154653 0,11942766 ! organ growth GO:0035265 15 7 0,000 0,04154653 0,11928515 ! purine salvage GO:0043101 10 7 0,000 0,04154653 0,11914297 ! nucleoside transport GO:0015858 8 7 0,000 0,04154653 0,11900114 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04154653 0,11885964 ! parturition GO:0007567 14 7 0,000 0,04154653 0,11871847 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04154653 0,11857765 ! rRNA modification GO:0000154 14 7 0,000 0,04154653 0,11843715 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04154653 0,11829699 ! spindle checkpoint GO:0031577 15 7 0,000 0,04154653 0,11815716 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04154653 0,11801766 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04154653 0,11787848 ! macrophage differentiation GO:0030225 11 7 0,000 0,04154653 0,11773964 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04154653 0,11760112 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04154653 0,11746293 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04154653 0,11732506 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04154653 0,11718752 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04154653 0,1170503 ! fibrinolysis GO:0042730 10 7 0,000 0,04154653 0,1169134 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04154653 0,11677682 ! eating behavior GO:0042755 7 7 0,000 0,04154653 0,11664055 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04154653 0,11650461 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04154653 0,11636898 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04154653 0,11623367 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04154653 0,11609867 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04154653 0,11596399 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04154653 0,11582961 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04154653 0,11569555 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04154653 0,1155618 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04154653 0,11542835 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04154653 0,11529522 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04154653 0,11516239 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04154653 0,11502987 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04154653 0,11489765 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04154653 0,11476573 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04154653 0,11463412 ! regulation of meiosis GO:0040020 12 7 0,000 0,04154653 0,11450281 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04154653 0,1143718 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04154653 0,11424109 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04154653 0,11411068 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04154653 0,11398056 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04154653 0,11385075 ! transcription termination GO:0006353 13 7 0,000 0,04154653 0,11372122 ! response to tumor cell GO:0002347 13 7 0,000 0,04154653 0,11359199 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04154653 0,11346306 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04154653 0,11333442 ! anaphase GO:0051322 17 7 0,000 0,04154653 0,11320606 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04154653 0,113078 ! axonal fasciculation GO:0007413 18 7 0,000 0,04154653 0,11295023 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04154653 0,11282275 GO:0045839|negative regulation of mitosis, ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04154653 0,11269555 ! diuresis GO:0030146 12 7 0,000 0,04154653 0,11256864 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04154653 0,11244202 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04154653 0,11231568 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04154653 0,11218962 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04154653 0,11206385 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04154653 0,11193836 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04154653 0,11181315 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04154653 0,11168822 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04154653 0,11156357 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04154653 0,11143919 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04154653 0,11131509 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04154653 0,11119127 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04154653 0,11106773 ! lymph node development GO:0048535 10 7 0,000 0,04154653 0,11094446 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04154653 0,11082146 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04154653 0,11069873 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04154653 0,11057628 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04154653 0,11045409 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04154653 0,11033218 ! adult feeding behavior GO:0008343 9 7 0,000 0,04154653 0,11021053 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04154653 0,11008916 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04154653 0,10996805 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04154653 0,1098472 ! muscle adaptation GO:0043500 14 7 0,000 0,04154653 0,10972662 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04154653 0,10960631 ! retina homeostasis GO:0001895 12 7 0,000 0,04154653 0,10948626 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04154653 0,10936647 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04154653 0,10924695 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04154653 0,10912768 ! protein prenylation GO:0018342 18 7 0,000 0,04154653 0,10900868 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04154653 0,10888993 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04154653 0,10877144 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04154653 0,10865321 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04233744 0,1106014 GO:0010863|positive regulation of phospholipase C activity, ! chloride transport GO:0006821 90 55 1,000 0,04376444 0,11420526 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04376444 0,11408153 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 1,000 0,04376444 0,11395806 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04376444 0,11383487 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04376444 0,11371193 ! RNA elongation GO:0006354 79 55 1,000 0,04376444 0,11358927 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04376444 0,11346687 ! regulation of actin filament length GO:0030832 105 56 1,000 0,04520917 0,11708639 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04520917 0,11696049 ! regulation of DNA replication GO:0006275 101 56 1,000 0,04520917 0,11683486 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04520917 0,1167095 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,04667135 0,12035506 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,04667135 0,1202262 ! lipid modification GO:0030258 97 57 1,000 0,04667135 0,12009761 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04667135 0,1199693 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,04667135 0,11984127 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04733991 0,12142838 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04733991 0,12129906 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04733991 0,12117002 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04733991 0,12104125 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04733991 0,12091276 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04733991 0,12078453 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04733991 0,12065658 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04733991 0,12052891 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04733991 0,1204015 ! meiotic prophase I GO:0007128 13 8 0,000 0,04733991 0,12027436 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04733991 0,12014749 ! oligopeptide transport GO:0006857 15 8 0,000 0,04733991 0,12002088 ! UTP metabolic process GO:0046051 8 8 0,000 0,04733991 0,11989454 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04733991 0,11976847 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04733991 0,11964266 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04733991 0,11951712 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04733991 0,11939184 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04733991 0,11926682 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04733991 0,11914207 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04733991 0,11901757 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04733991 0,11889334 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04733991 0,11876936 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04733991 0,11864564 ! reflex GO:0060004 16 8 0,000 0,04733991 0,11852218 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04733991 0,11839898 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04733991 0,11827603 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04733991 0,11815334 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04733991 0,1180309 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04733991 0,11790871 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04733991 0,11778678 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04733991 0,1176651 ! pigment granule organization GO:0048753 16 8 0,000 0,04733991 0,11754367 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04733991 0,11742249 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04733991 0,11730156 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04733991 0,11718088 ! histidine metabolic process GO:0006547 16 8 0,000 0,04733991 0,11706045 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04733991 0,11694026 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04733991 0,11682032 ! glycine catabolic process GO:0006546 13 8 0,000 0,04733991 0,11670063 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04733991 0,11658118 ! ER overload response GO:0006983 12 8 0,000 0,04733991 0,11646198 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04733991 0,11634302 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04733991 0,1162243 ! melanin metabolic process GO:0006582 15 8 0,000 0,04733991 0,11610583 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04733991 0,11598759 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04733991 0,1158696 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04733991 0,11575185 ! macrophage activation GO:0042116 12 8 0,000 0,04733991 0,11563433 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04733991 0,11551705 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04733991 0,11540002 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04733991 0,11528321 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04733991 0,11516665 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04733991 0,11505032 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04733991 0,11493422 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04733991 0,11481836 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04733991 0,11470274 ! osteoblast development GO:0002076 16 8 0,000 0,04733991 0,11458734 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04733991 0,11447218 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04733991 0,11435725 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04733991 0,11424254 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04733991 0,11412807 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04733991 0,11401383 ! response to UV-B GO:0010224 16 8 0,000 0,04733991 0,11389982 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04733991 0,11378603 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04733991 0,11367247 ! intermediate filament organization GO:0045109 12 8 0,000 0,04733991 0,11355914 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04733991 0,11344603 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04733991 0,11333315 ! cellular extravasation GO:0045123 12 8 0,000 0,04733991 0,11322049 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04733991 0,11310806 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04733991 0,11299585 ! response to antibiotic GO:0046677 11 8 0,000 0,04733991 0,11288386 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04733991 0,1127721 ! DNA topological change GO:0006265 12 8 0,000 0,04733991 0,11266055 ! response to tropane GO:0014073 15 8 0,000 0,04733991 0,11254923 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04733991 0,11243812 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,04733991 0,11232723 ! melanosome transport GO:0032402 13 8 0,000 0,04733991 0,11221657 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04733991 0,11210612 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04733991 0,11199589 ! mast cell activation GO:0045576 14 8 0,000 0,04733991 0,11188587 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04733991 0,11177607 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04733991 0,11166649 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04733991 0,11155712 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04733991 0,11144796 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04733991 0,11133902 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04733991 0,11123029 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04733991 0,11112177 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04733991 0,11101347 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04733991 0,11090537 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04733991 0,11079749 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04733991 0,11068981 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04733991 0,11058235 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04733991 0,11047509 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04733991 0,11036804 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04733991 0,1102612 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04733991 0,11015456 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04733991 0,11004813 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04733991 0,10994191 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04733991 0,10983589 ! hormone catabolic process GO:0042447 17 8 0,000 0,04733991 0,10973007 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04733991 0,10962446 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04733991 0,10951905 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04733991 0,10941385 ! ATP catabolic process GO:0006200 11 8 0,000 0,04733991 0,10930884 ! blastocyst growth GO:0001832 19 8 0,000 0,04733991 0,10920404 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04733991 0,10909944 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04733991 0,10899504 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04733991 0,10889084 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04733991 0,10878683 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04733991 0,10868303 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04733991 0,10857942 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04733991 0,10847602 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04733991 0,1083728 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04733991 0,10826979 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04733991 0,10816697 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04733991 0,10806434 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04733991 0,10796191 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04733991 0,10785967 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04733991 0,10775763 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04733991 0,10765578 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04733991 0,10755412 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04733991 0,10745266 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,04815073 0,10919007 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04815073 0,10908725 ! regulation of cellular component size GO:0032535 109 59 1,000 0,04964705 0,11237141 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04964705 0,1122658 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04964705 0,11216039 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,05268949 0,11892206 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05309846 0,11973279 ! axon extension GO:0048675 15 9 0,000 0,05309846 0,11962068 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05309846 0,11950878 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05309846 0,11939709 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05309846 0,11928561 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05309846 0,11917433 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05309846 0,11906327 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05309846 0,11895241 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05309846 0,11884175 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05309846 0,1187313 ! phosphate transport GO:0006817 19 9 0,000 0,05309846 0,11862106 ! reproductive behavior GO:0019098 19 9 0,000 0,05309846 0,11851102 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05309846 0,11840119 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05309846 0,11829156 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05309846 0,11818213 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05309846 0,11807291 ! GTP metabolic process GO:0046039 9 9 0,000 0,05309846 0,11796388 ! RNA methylation GO:0001510 15 9 0,000 0,05309846 0,11785506 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05309846 0,11774644 ! artery development GO:0060840 24 9 0,000 0,05309846 0,11763801 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05309846 0,11752979 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05309846 0,11742177 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05309846 0,11731394 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05309846 0,11720632 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05309846 0,11709889 ! chemosensory behavior GO:0007635 20 9 0,000 0,05309846 0,11699165 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05309846 0,11688461 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05309846 0,11677777 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05309846 0,11667113 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05309846 0,11656468 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05309846 0,11645842 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05309846 0,11635235 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05309846 0,11624648 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05309846 0,1161408 ! protein targeting to ER GO:0045047 22 9 0,000 0,05309846 0,11603532 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05309846 0,11593002 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05309846 0,11582492 ! T cell selection GO:0045058 23 9 0,000 0,05309846 0,11572 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05309846 0,11561528 ! endosome organization GO:0007032 17 9 0,000 0,05309846 0,11551074 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05309846 0,1154064 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05309846 0,11530224 ! mannose metabolic process GO:0006013 13 9 0,000 0,05309846 0,11519827 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05309846 0,11509449 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05309846 0,11499089 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05309846 0,11488749 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05309846 0,11478426 ! ruffle organization GO:0031529 15 9 0,000 0,05309846 0,11468122 ! retinol metabolic process GO:0042572 18 9 0,000 0,05309846 0,11457837 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05309846 0,1144757 ! behavioral fear response GO:0001662 22 9 0,000 0,05309846 0,11437322 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05309846 0,11427092 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05309846 0,1141688 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05309846 0,11406686 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,05309846 0,11396511 ! protein heterooligomerization GO:0051291 16 9 0,000 0,05309846 0,11386353 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05309846 0,11376214 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05309846 0,11366093 ! segment specification GO:0007379 13 9 0,000 0,05309846 0,1135599 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05309846 0,11345904 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05309846 0,11335837 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05309846 0,11325788 ! response to amine stimulus GO:0014075 13 9 0,000 0,05309846 0,11315756 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05309846 0,11305742 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05309846 0,11295746 ! erythrocyte development GO:0048821 15 9 0,000 0,05309846 0,11285767 ! gas homeostasis GO:0033483 16 9 0,000 0,05309846 0,11275806 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05309846 0,11265863 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05309846 0,11255937 ! renal water homeostasis GO:0003091 14 9 0,000 0,05309846 0,11246029 ! postreplication repair GO:0006301 22 9 0,000 0,05309846 0,11236138 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05309846 0,11226264 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05309846 0,11216408 ! icosanoid secretion GO:0032309 15 9 0,000 0,05309846 0,11206569 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05309846 0,11196747 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05309846 0,11186943 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05309846 0,11177155 ! regulation of cell division GO:0051302 15 9 0,000 0,05309846 0,11167385 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05309846 0,11157632 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05309846 0,11147896 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05309846 0,11138176 ! sterol catabolic process GO:0016127 11 9 0,000 0,05309846 0,11128474 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05309846 0,11118789 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05309846 0,1110912 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05309846 0,11099469 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05309846 0,11089834 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05309846 0,11080215 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05309846 0,11070614 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05309846 0,11061029 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05309846 0,11051461 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05309846 0,11041909 ! purine base metabolic process GO:0006144 21 9 0,000 0,05309846 0,11032373 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05309846 0,11022855 ! pigment granule transport GO:0051904 17 9 0,000 0,05309846 0,11013352 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05309846 0,11003866 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05309846 0,10994396 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05309846 0,10984943 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05309846 0,10975505 ! ear development GO:0043583 103 62 1,000 0,05423511 0,1120083 ! cellular amino acid catabolic process GO:0009063 101 63 1,000 0,05579665 0,11513442 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,05737387 0,11828753 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,05737387 0,11818625 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05882239 0,12106643 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05882239 0,12096296 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05882239 0,12085966 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05882239 0,12075654 ! synapsis GO:0007129 13 10 0,000 0,05882239 0,12065359 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05882239 0,12055082 ! N-glycan processing GO:0006491 20 10 0,000 0,05882239 0,12044822 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05882239 0,1203458 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05882239 0,12024355 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05882239 0,12014148 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05882239 0,12003958 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05882239 0,11993785 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05882239 0,11983629 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05882239 0,11973491 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05882239 0,11963369 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05882239 0,11953265 ! androgen metabolic process GO:0008209 17 10 0,000 0,05882239 0,11943178 ! phospholipid efflux GO:0033700 16 10 0,000 0,05882239 0,11933108 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05882239 0,11923055 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05882239 0,11913018 ! lung alveolus development GO:0048286 26 10 0,000 0,05882239 0,11902999 ! pathogenesis GO:0009405 13 10 0,000 0,05882239 0,11892997 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05882239 0,11883011 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05882239 0,11873042 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05882239 0,1186309 ! endoderm development GO:0007492 16 10 0,000 0,05882239 0,11853154 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05882239 0,11843235 ! arginine catabolic process GO:0006527 13 10 0,000 0,05882239 0,11833333 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05882239 0,11823447 ! proline metabolic process GO:0006560 13 10 0,000 0,05882239 0,11813578 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05882239 0,11803725 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05882239 0,11793888 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05882239 0,11784068 ! V(D)J recombination GO:0033151 28 10 0,000 0,05882239 0,11774264 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05882239 0,11764477 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05882239 0,11754706 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05882239 0,11744951 ! B cell proliferation GO:0042100 18 10 0,000 0,05882239 0,11735212 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05882239 0,1172549 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05882239 0,11715783 ! multicellular organism growth GO:0035264 18 10 0,000 0,05882239 0,11706093 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05882239 0,11696418 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05882239 0,1168676 ! epithelial cell development GO:0002064 20 10 0,000 0,05882239 0,11677117 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05882239 0,1166749 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05882239 0,1165788 ! macroautophagy GO:0016236 17 10 0,000 0,05882239 0,11648285 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05882239 0,11638706 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05882239 0,11629142 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05882239 0,11619594 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05882239 0,11610062 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05882239 0,11600546 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05882239 0,11591045 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05882239 0,1158156 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05882239 0,1157209 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05882239 0,11562636 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05882239 0,11553197 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05882239 0,11543773 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05882239 0,11534365 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05882239 0,11524972 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05882239 0,11515595 ! DNA ligation GO:0006266 19 10 0,000 0,05882239 0,11506232 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05882239 0,11496885 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05882239 0,11487554 ! melanosome localization GO:0032400 16 10 0,000 0,05882239 0,11478237 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05882239 0,11468935 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05882239 0,11459649 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05882239 0,11450377 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05882239 0,1144112 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05882239 0,11431879 ! mRNA cleavage GO:0006379 17 10 0,000 0,05882239 0,11422652 ! protein sumoylation GO:0016925 15 10 0,000 0,05882239 0,1141344 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05882239 0,11404243 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05882239 0,11395061 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05882239 0,11385894 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05882239 0,11376741 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05882239 0,11367603 ! salivary gland development GO:0007431 27 10 0,000 0,05882239 0,1135848 ! prophase GO:0051324 15 10 0,000 0,05882239 0,11349371 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05882239 0,11340277 ! apical protein localization GO:0045176 15 10 0,000 0,05882239 0,11331198 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05882239 0,11322133 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05882239 0,11313082 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05882239 0,11304046 ! midbrain development GO:0030901 13 10 0,000 0,05882239 0,11295025 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05882239 0,11286017 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05882239 0,11277025 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05882239 0,11268046 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05882239 0,11259082 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05882239 0,11250132 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05882239 0,11241196 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05882239 0,11232275 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05882239 0,11223367 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05882239 0,11214474 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05882239 0,11205595 ! blastocyst formation GO:0001825 17 10 0,000 0,05882239 0,11196729 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05882239 0,11187878 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05882239 0,11179041 ! activation of innate immune response GO:0002218 12 10 0,000 0,05882239 0,11170218 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05882239 0,11161408 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05882239 0,11152613 ! response to nicotine GO:0035094 20 10 0,000 0,05882239 0,11143831 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05882239 0,11135064 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05882239 0,1112631 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05882239 0,11117569 ! germ cell development GO:0007281 118 65 1,000 0,05896654 0,11136067 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,0605744 0,11430746 ! extracellular matrix organization GO:0030198 133 66 1,000 0,0605744 0,11421787 ! cell projection assembly GO:0030031 120 66 1,000 0,0605744 0,11412843 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,06219722 0,11709429 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,06219722 0,11700274 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06219722 0,11691133 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,06219722 0,11682007 ! hexose catabolic process GO:0019320 104 67 1,000 0,06219722 0,11672895 ! adaptive immune response GO:0002250 119 67 1,000 0,06219722 0,11663796 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,06219722 0,11654712 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06383476 0,11952251 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,06383476 0,11942957 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0645119 0,12060267 ! respiratory burst GO:0045730 17 11 0,000 0,0645119 0,12050904 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0645119 0,12041555 ! neuron fate specification GO:0048665 17 11 0,000 0,0645119 0,1203222 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0645119 0,120229 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0645119 0,12013594 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0645119 0,12004303 ! thyroid gland development GO:0030878 26 11 0,000 0,0645119 0,11995026 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0645119 0,11985764 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0645119 0,11976515 ! response to pain GO:0048265 24 11 0,000 0,0645119 0,11967281 ! T cell proliferation GO:0042098 26 11 0,000 0,0645119 0,11958062 ! blood vessel remodeling GO:0001974 29 11 0,000 0,0645119 0,11948856 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0645119 0,11939665 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,0645119 0,11930487 ! bone resorption GO:0045453 16 11 0,000 0,0645119 0,11921324 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,0645119 0,11912175 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0645119 0,1190304 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0645119 0,11893919 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0645119 0,11884812 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0645119 0,11875718 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0645119 0,11866639 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0645119 0,11857574 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0645119 0,11848522 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0645119 0,11839484 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0645119 0,1183046 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,0645119 0,1182145 ! lipid digestion GO:0044241 18 11 0,000 0,0645119 0,11812454 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0645119 0,11803471 ! UV protection GO:0009650 19 11 0,000 0,0645119 0,11794502 ! adult heart development GO:0007512 14 11 0,000 0,0645119 0,11785546 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0645119 0,11776604 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0645119 0,11767676 ! temperature homeostasis GO:0001659 17 11 0,000 0,0645119 0,11758761 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0645119 0,11749859 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0645119 0,11740971 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0645119 0,11732097 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,0645119 0,11723236 ! regulation of organ growth GO:0046620 13 11 0,000 0,0645119 0,11714388 ! pigment granule localization GO:0051875 20 11 0,000 0,0645119 0,11705554 ! vasoconstriction GO:0042310 18 11 0,000 0,0645119 0,11696732 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0645119 0,11687925 ! embryonic axis specification GO:0000578 18 11 0,000 0,0645119 0,1167913 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0645119 0,11670349 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0645119 0,11661581 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0645119 0,11652826 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0645119 0,11644084 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0645119 0,11635355 ! zymogen activation GO:0031638 15 11 0,000 0,0645119 0,1162664 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0645119 0,11617937 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0645119 0,11609248 ! nucleosome positioning GO:0016584 15 11 0,000 0,0645119 0,11600571 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0645119 0,11591907 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0645119 0,11583257 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0645119 0,11574619 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,0645119 0,11565994 ! acid secretion GO:0046717 18 11 0,000 0,0645119 0,11557382 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0645119 0,11548783 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0645119 0,11540196 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0645119 0,11531623 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0645119 0,11523062 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,0645119 0,11514513 ! cholesterol efflux GO:0033344 19 11 0,000 0,0645119 0,11505978 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0645119 0,11497455 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0645119 0,11488944 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,0645119 0,11480447 ! embryonic gut development GO:0048566 15 11 0,000 0,0645119 0,11471962 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0645119 0,11463489 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0645119 0,11455029 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,0645119 0,11446581 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0645119 0,11438146 ! defense response to fungus GO:0050832 13 11 0,000 0,0645119 0,11429723 ! developmental induction GO:0031128 19 11 0,000 0,0645119 0,11421313 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0645119 0,11412915 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0645119 0,11404529 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,0645119 0,11396156 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0645119 0,11387795 ! regulation of embryonic development GO:0045995 27 11 0,000 0,0645119 0,11379446 ! nucleus localization GO:0051647 19 11 0,000 0,0645119 0,11371109 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0645119 0,11362785 ! negative regulation of cell size GO:0045792 134 69 1,000 0,06548678 0,11526057 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06548678 0,11517631 ! amine catabolic process GO:0009310 117 71 1,000 0,06883336 0,12097374 ! humoral immune response GO:0006959 109 71 1,000 0,06883336 0,12088544 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06883336 0,12079727 ! regulation of immune effector process GO:0002697 137 71 1,000 0,06883336 0,12070922 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07016722 0,12295872 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07016722 0,12286923 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07016722 0,12277987 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07016722 0,12269064 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07016722 0,12260154 ! virus-host interaction GO:0019048 29 12 0,000 0,07016722 0,12251257 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07016722 0,12242373 ! cartilage condensation GO:0001502 20 12 0,000 0,07016722 0,12233502 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,07016722 0,12224643 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,07016722 0,12215798 ! protein complex disassembly GO:0043241 27 12 0,000 0,07016722 0,12206965 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07016722 0,12198145 ! hippocampus development GO:0021766 26 12 0,000 0,07016722 0,12189337 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07016722 0,12180543 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07016722 0,12171761 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07016722 0,12162991 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07016722 0,12154235 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07016722 0,12145491 ! drug transport GO:0015893 16 12 0,000 0,07016722 0,12136759 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07016722 0,1212804 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07016722 0,12119334 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07016722 0,1211064 ! focal adhesion formation GO:0048041 35 12 0,000 0,07016722 0,12101959 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07016722 0,1209329 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07016722 0,12084633 ! forebrain cell migration GO:0021885 21 12 0,000 0,07016722 0,12075989 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07016722 0,12067357 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07016722 0,12058737 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07016722 0,1205013 ! entry into host cell GO:0030260 32 12 0,000 0,07016722 0,12041535 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07016722 0,12032952 ! monoamine transport GO:0015844 18 12 0,000 0,07016722 0,12024382 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07016722 0,12015824 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07016722 0,12007277 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07016722 0,11998744 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07016722 0,11990222 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07016722 0,11981712 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07016722 0,11973214 ! protein homotetramerization GO:0051289 21 12 0,000 0,07016722 0,11964729 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07016722 0,11956255 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07016722 0,11947793 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07016722 0,11939344 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07016722 0,11930906 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07016722 0,1192248 ! fucose catabolic process GO:0019317 22 12 0,000 0,07016722 0,11914066 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07016722 0,11905664 ! histone acetylation GO:0016573 26 12 0,000 0,07016722 0,11897274 ! histone methylation GO:0016571 26 12 0,000 0,07016722 0,11888896 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07016722 0,11880529 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07016722 0,11872175 ! gland morphogenesis GO:0022612 29 12 0,000 0,07016722 0,11863831 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07016722 0,118555 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,07016722 0,1184718 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07016722 0,11838872 ! spleen development GO:0048536 22 12 0,000 0,07016722 0,11830576 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,07016722 0,11822291 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07016722 0,11814018 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07016722 0,11805757 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07016722 0,11797507 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07016722 0,11789268 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07016722 0,11781041 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07016722 0,11772826 ! response to cold GO:0009409 17 12 0,000 0,07016722 0,11764622 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07016722 0,11756429 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07016722 0,11748248 ! regulation of caspase activity GO:0043281 122 72 1,000 0,07052745 0,11800351 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,07052745 0,1179215 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,07052745 0,11783961 ! learning or memory GO:0007611 147 73 1,000 0,07223511 0,12060907 ! meiosis GO:0007126 121 74 1,000 0,07395612 0,12339696 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,07395612 0,12331144 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,07395612 0,12322605 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,07395612 0,12314077 ! organelle localization GO:0051640 136 74 1,000 0,07395612 0,12305561 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07569024 0,12585399 ! meiotic cell cycle GO:0051321 122 75 1,000 0,07569024 0,12576708 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07578853 0,12584348 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07578853 0,12575669 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07578853 0,12567002 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07578853 0,12558347 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07578853 0,12549704 ! lipid localization GO:0010876 28 13 0,000 0,07578853 0,12541073 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07578853 0,12532453 ! organelle fusion GO:0048284 32 13 0,000 0,07578853 0,12523846 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07578853 0,1251525 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07578853 0,12506666 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07578853 0,12498094 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07578853 0,12489534 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07578853 0,12480985 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07578853 0,12472448 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07578853 0,12463923 ! methionine metabolic process GO:0006555 27 13 0,000 0,07578853 0,1245541 ! plasma membrane organization GO:0007009 24 13 0,000 0,07578853 0,12446908 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07578853 0,12438417 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07578853 0,12429938 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07578853 0,12421471 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07578853 0,12413015 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07578853 0,12404571 ! response to X-ray GO:0010165 25 13 0,000 0,07578853 0,12396138 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07578853 0,12387717 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07578853 0,12379307 ! exocrine system development GO:0035272 32 13 0,000 0,07578853 0,12370909 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07578853 0,12362522 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07578853 0,12354146 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07578853 0,12345782 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07578853 0,12337429 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07578853 0,12329087 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07578853 0,12320756 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07578853 0,12312437 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07578853 0,12304129 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07578853 0,12295832 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07578853 0,12287547 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07578853 0,12279272 ! ribosome assembly GO:0042255 17 13 0,000 0,07578853 0,12271009 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07578853 0,12262757 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07578853 0,12254516 ! chromatin silencing GO:0006342 26 13 0,000 0,07578853 0,12246286 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07578853 0,12238067 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07578853 0,12229859 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07578853 0,12221662 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07578853 0,12213476 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07578853 0,12205301 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07578853 0,12197137 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07578853 0,12188984 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07578853 0,12180841 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07578853 0,1217271 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07578853 0,12164589 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07578853 0,1215648 ! embryonic placenta development GO:0001892 23 13 0,000 0,07578853 0,12148381 ! insulin secretion GO:0030073 23 13 0,000 0,07578853 0,12140293 ! actin filament polymerization GO:0030041 24 13 0,000 0,07578853 0,12132215 ! acrosome reaction GO:0007340 18 13 0,000 0,07578853 0,12124149 ! defense response to bacterium GO:0042742 89 76 1,000 0,07743728 0,12379674 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,07743728 0,12371453 ! regulation of catabolic process GO:0009894 161 76 1,000 0,07743728 0,12363244 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,07919699 0,12635807 ! blood coagulation GO:0007596 146 78 1,000 0,08096918 0,12909997 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,08096918 0,12901447 ! rRNA transcription GO:0009303 25 14 0,000 0,08137604 0,12957694 ! lactation GO:0007595 26 14 0,000 0,08137604 0,12949124 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,08137604 0,12940565 ! reproductive cellular process GO:0048610 20 14 0,000 0,08137604 0,12932018 ! tRNA modification GO:0006400 20 14 0,000 0,08137604 0,12923482 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08137604 0,12914957 ! regulation of S phase GO:0033261 23 14 0,000 0,08137604 0,12906444 ! water transport GO:0006833 21 14 0,000 0,08137604 0,12897941 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08137604 0,1288945 ! non-recombinational repair GO:0000726 25 14 0,000 0,08137604 0,12880971 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08137604 0,12872502 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08137604 0,12864044 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08137604 0,12855598 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08137604 0,12847162 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08137604 0,12838738 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08137604 0,12830324 ! palate development GO:0060021 31 14 0,000 0,08137604 0,12821922 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08137604 0,12813531 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08137604 0,12805151 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08137604 0,12796781 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08137604 0,12788423 ! arginine metabolic process GO:0006525 17 14 0,000 0,08137604 0,12780075 ! regulation of heart rate GO:0002027 24 14 0,000 0,08137604 0,12771739 ! organic alcohol transport GO:0015850 29 14 0,000 0,08137604 0,12763413 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08137604 0,12755098 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,08137604 0,12746794 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08137604 0,127385 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08137604 0,12730218 ! L-amino acid transport GO:0015807 30 14 0,000 0,08137604 0,12721946 ! bone mineralization GO:0030282 17 14 0,000 0,08137604 0,12713685 ! stem cell development GO:0048864 43 14 0,000 0,08137604 0,12705435 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08137604 0,12697195 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08137604 0,12688966 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08137604 0,12680748 ! cerebellum development GO:0021549 21 14 0,000 0,08137604 0,12672541 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08137604 0,12664344 ! response to gamma radiation GO:0010332 28 14 0,000 0,08137604 0,12656157 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08137604 0,12647981 ! cofactor transport GO:0051181 26 14 0,000 0,08137604 0,12639816 ! NADP metabolic process GO:0006739 24 14 0,000 0,08137604 0,12631661 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08137604 0,12623517 ! intestinal absorption GO:0050892 25 14 0,000 0,08137604 0,12615383 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08137604 0,1260726 ! oxygen transport GO:0015671 21 14 0,000 0,08137604 0,12599147 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08137604 0,12591045 ! male genitalia development GO:0030539 24 14 0,000 0,08137604 0,12582953 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08137604 0,12574872 ! regulation of axon extension GO:0030516 37 14 0,000 0,08137604 0,125668 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08137604 0,1255874 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,08275363 0,12763156 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,08275363 0,1275498 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,08455013 0,13023534 ! muscle cell differentiation GO:0042692 159 80 1,000 0,08455013 0,13015202 ! inorganic anion transport GO:0015698 138 80 1,000 0,08455013 0,1300688 ! T cell activation GO:0042110 168 81 1,000 0,08635846 0,13276579 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08635846 0,13268101 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08692996 0,13347382 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08692996 0,1333887 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08692996 0,13330368 ! superoxide anion generation GO:0042554 20 15 0,000 0,08692996 0,13321877 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,08692996 0,13313398 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08692996 0,13304928 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08692996 0,1329647 ! copper ion transport GO:0006825 20 15 0,000 0,08692996 0,13288023 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08692996 0,13279586 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08692996 0,1327116 ! sulfate transport GO:0008272 23 15 0,000 0,08692996 0,13262744 ! response to cAMP GO:0051591 22 15 0,000 0,08692996 0,13254339 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08692996 0,13245945 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08692996 0,13237562 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08692996 0,13229189 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08692996 0,13220827 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08692996 0,13212475 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08692996 0,13204134 ! pituitary gland development GO:0021983 29 15 0,000 0,08692996 0,13195803 ! vesicle coating GO:0006901 33 15 0,000 0,08692996 0,13187483 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08692996 0,13179173 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08692996 0,13170874 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08692996 0,13162585 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08692996 0,13154307 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08692996 0,13146039 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08692996 0,13137781 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08692996 0,13129534 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08692996 0,13121297 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08692996 0,13113071 ! histone deacetylation GO:0016575 20 15 0,000 0,08692996 0,13104854 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08692996 0,13096648 ! tissue regeneration GO:0042246 26 15 0,000 0,08692996 0,13088453 ! water homeostasis GO:0030104 27 15 0,000 0,08692996 0,13080267 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08692996 0,13072092 ! muscle maintenance GO:0046716 26 15 0,000 0,08692996 0,13063927 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08692996 0,13055773 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08692996 0,13047628 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08692996 0,13039494 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08692996 0,13031369 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08692996 0,13023255 ! detection of bacterium GO:0016045 18 15 0,000 0,08692996 0,13015151 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08692996 0,13007057 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08692996 0,12998973 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08692996 0,12990899 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08692996 0,12982835 ! peptide hormone processing GO:0016486 23 15 0,000 0,08692996 0,12974781 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08817843 0,13152963 ! response to drug GO:0042493 143 82 1,000 0,08817843 0,13144814 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,08817843 0,13136674 ! regulation of lyase activity GO:0051339 160 83 1,000 0,09000982 0,13401214 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,09185243 0,13667097 ! hemostasis GO:0007599 158 84 1,000 0,09185243 0,1365865 ! negative regulation of growth GO:0045926 155 84 1,000 0,09185243 0,13650213 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,09245048 0,13730608 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,09245048 0,13722138 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09245048 0,13713678 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09245048 0,13705228 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09245048 0,13696789 ! bone remodeling GO:0046849 27 16 0,000 0,09245048 0,1368836 ! filopodium assembly GO:0046847 32 16 0,000 0,09245048 0,13679942 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09245048 0,13671534 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09245048 0,13663136 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09245048 0,13654748 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09245048 0,13646371 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09245048 0,13638004 ! startle response GO:0001964 28 16 0,000 0,09245048 0,13629648 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09245048 0,13621301 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09245048 0,13612965 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09245048 0,13604639 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09245048 0,13596323 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09245048 0,13588018 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09245048 0,13579722 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09245048 0,13571437 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09245048 0,13563162 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09245048 0,13554896 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09245048 0,13546641 ! fructose metabolic process GO:0006000 25 16 0,000 0,09245048 0,13538396 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09245048 0,13530161 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09245048 0,13521936 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09245048 0,13513721 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09245048 0,13505516 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09245048 0,13497321 ! axon cargo transport GO:0008088 43 16 0,000 0,09245048 0,13489136 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09245048 0,13480961 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09245048 0,13472795 ! DNA replication initiation GO:0006270 27 16 0,000 0,09245048 0,1346464 ! neuron recognition GO:0008038 35 16 0,000 0,09245048 0,13456494 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09245048 0,13448359 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09245048 0,13440233 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09245048 0,13432117 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09245048 0,1342401 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,09245048 0,13415914 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09245048 0,13407827 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09245048 0,1339975 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09245048 0,13391683 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09245048 0,13383625 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09245048 0,13375577 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09245048 0,13367539 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09245048 0,13359511 ! defense response to virus GO:0051607 37 16 0,000 0,09245048 0,13351492 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,09370607 0,13524704 ! alcohol catabolic process GO:0046164 130 86 1,000 0,09557054 0,13785535 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09744563 0,14047585 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,09744563 0,14039173 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0979378 0,14101637 ! metencephalon development GO:0022037 30 17 0,000 0,0979378 0,14093203 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0979378 0,14084779 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0979378 0,14076366 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0979378 0,14067962 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0979378 0,14059568 ! endothelial cell migration GO:0043542 28 17 0,000 0,0979378 0,14051184 ! inositol metabolic process GO:0006020 28 17 0,000 0,0979378 0,1404281 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0979378 0,14034447 ! glial cell development GO:0021782 27 17 0,000 0,0979378 0,14026093 ! limbic system development GO:0021761 36 17 0,000 0,0979378 0,14017749 ! adult walking behavior GO:0007628 33 17 0,000 0,0979378 0,14009415 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0979378 0,14001091 ! heart looping GO:0001947 30 17 0,000 0,0979378 0,13992777 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0979378 0,13984472 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0979378 0,13976178 ! myoblast differentiation GO:0045445 45 17 0,000 0,0979378 0,13967893 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0979378 0,13959618 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0979378 0,13951353 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0979378 0,13943098 ! glycine metabolic process GO:0006544 28 17 0,000 0,0979378 0,13934853 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0979378 0,13926617 ! NAD metabolic process GO:0019674 29 17 0,000 0,0979378 0,13918391 ! membrane budding GO:0006900 37 17 0,000 0,0979378 0,13910175 ! DNA integration GO:0015074 29 17 0,000 0,0979378 0,13901968 ! regulation of protein binding GO:0043393 33 17 0,000 0,0979378 0,13893771 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0979378 0,13885584 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0979378 0,13877406 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0979378 0,13869238 ! genitalia development GO:0048806 30 17 0,000 0,0979378 0,1386108 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0979378 0,13852931 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0979378 0,13844792 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,0979378 0,13836662 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0979378 0,13828542 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0979378 0,13820432 ! steroid catabolic process GO:0006706 31 17 0,000 0,0979378 0,13812331 ! gas transport GO:0015669 25 17 0,000 0,0979378 0,13804239 ! organic cation transport GO:0015695 31 17 0,000 0,0979378 0,13796157 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0979378 0,13788084 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0979378 0,13780021 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0979378 0,13771967 ! microspike assembly GO:0030035 36 17 0,000 0,0979378 0,13763923 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0979378 0,13755888 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0979378 0,13747862 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,09933116 0,13935322 ! ATP biosynthetic process GO:0006754 159 88 1,000 0,09933116 0,13927201 ! ossification GO:0001503 188 90 1,000 0,10313274 0,14451798 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,10313274 0,14443386 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10339213 0,1447129 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10339213 0,14462876 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10339213 0,14454473 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10339213 0,14446079 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10339213 0,14437694 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10339213 0,1442932 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10339213 0,14420955 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10339213 0,144126 ! patterning of blood vessels GO:0001569 39 18 0,000 0,10339213 0,14404255 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10339213 0,14395919 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10339213 0,14387593 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,10339213 0,14379276 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10339213 0,14370969 ! response to retinoic acid GO:0032526 26 18 0,000 0,10339213 0,14362672 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,10339213 0,14354384 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,10339213 0,14346106 ! response to fungus GO:0009620 21 18 0,000 0,10339213 0,14337837 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10339213 0,14329578 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10339213 0,14321328 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10339213 0,14313088 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10339213 0,14304858 ! vitamin transport GO:0051180 27 18 0,000 0,10339213 0,14296637 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10339213 0,14288425 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10339213 0,14280222 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10339213 0,1427203 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10339213 0,14263846 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,10339213 0,14255672 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10339213 0,14247507 ! bone development GO:0060348 189 91 1,000 0,10504842 0,14467458 ! response to protein stimulus GO:0051789 149 91 1,000 0,10504842 0,14459182 ! protein secretion GO:0009306 39 19 0,000 0,10881366 0,14968878 ! positive regulation of translation GO:0045727 30 19 0,000 0,10881366 0,14960324 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10881366 0,14951781 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10881366 0,14943246 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10881366 0,14934722 ! skin development GO:0043588 36 19 0,000 0,10881366 0,14926207 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10881366 0,14917702 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10881366 0,14909207 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10881366 0,14900722 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10881366 0,14892246 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10881366 0,14883779 ! cerebral cortex development GO:0021987 36 19 0,000 0,10881366 0,14875323 ! pigmentation during development GO:0048066 41 19 0,000 0,10881366 0,14866875 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10881366 0,14858438 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10881366 0,1485001 ! heme metabolic process GO:0042168 36 19 0,000 0,10881366 0,14841592 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10881366 0,14833183 ! neuromuscular junction development GO:0007528 34 19 0,000 0,10881366 0,14824784 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10881366 0,14816394 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10881366 0,14808013 ! protein export from nucleus GO:0006611 36 19 0,000 0,10881366 0,14799643 ! heart process GO:0003015 30 19 0,000 0,10881366 0,14791281 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10881366 0,14782929 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,10881366 0,14774587 ! cellular pigmentation GO:0033059 36 19 0,000 0,10881366 0,14766254 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10881366 0,1475793 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10881366 0,14749616 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10881366 0,14741311 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10881366 0,14733015 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10881366 0,14724729 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10881366 0,14716452 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10881366 0,14708184 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10881366 0,14699926 ! cilium assembly GO:0042384 37 19 0,000 0,10881366 0,14691677 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10881366 0,14683437 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10890861 0,14688011 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,10890861 0,14679782 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,11280602 0,15196601 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11420259 0,1537613 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11420259 0,1536753 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11420259 0,1535894 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11420259 0,15350359 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,11420259 0,15341789 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11420259 0,15333227 ! response to vitamin GO:0033273 31 20 0,000 0,11420259 0,15324676 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11420259 0,15316133 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,11420259 0,15307601 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11420259 0,15299078 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11420259 0,15290564 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11420259 0,1528206 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11420259 0,15273565 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11420259 0,1526508 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11420259 0,15256604 GO:0032392|DNA geometric change, ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11420259 0,15248137 ! body fluid secretion GO:0007589 31 20 0,000 0,11420259 0,1523968 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11420259 0,15231232 ! peptide secretion GO:0002790 35 20 0,000 0,11420259 0,15222794 ! stem cell differentiation GO:0048863 53 20 0,000 0,11420259 0,15214365 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11420259 0,15205945 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11420259 0,15197535 ! sensory perception of pain GO:0019233 30 20 0,000 0,11420259 0,15189134 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11420259 0,15180742 ! diencephalon development GO:0021536 34 20 0,000 0,11420259 0,1517236 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11420259 0,15163986 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11420259 0,15155622 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11420259 0,15147268 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,11420259 0,15138922 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11420259 0,15130586 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11420259 0,15122258 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11420259 0,1511394 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11420259 0,15105631 ! regulation of glucose import GO:0046324 29 20 0,000 0,11420259 0,15097332 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11420259 0,15089041 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11420259 0,15080759 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11420259 0,15072487 ! negative regulation of translation GO:0017148 29 20 0,000 0,11420259 0,15064223 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11420259 0,15055969 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 1,000 0,11476823 0,15122255 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 1,000 0,11673921 0,15373538 ! response to virus GO:0009615 160 98 1,000 0,11871878 0,15625677 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 1,000 0,11871878 0,15617134 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,11871878 0,156086 GO:0016054|organic acid catabolic process, ! regulation of cell killing GO:0031341 42 21 0,000 0,11955911 0,15710498 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11955911 0,15701922 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11955911 0,15693356 ! hormone secretion GO:0046879 38 21 0,000 0,11955911 0,15684799 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11955911 0,15676252 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11955911 0,15667713 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11955911 0,15659184 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11955911 0,15650665 ! axis specification GO:0009798 38 21 0,000 0,11955911 0,15642154 ! ovarian follicle development GO:0001541 35 21 0,000 0,11955911 0,15633653 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11955911 0,15625161 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11955911 0,15616678 ! cell aging GO:0007569 44 21 0,000 0,11955911 0,15608205 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11955911 0,15599741 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11955911 0,15591285 ! cytolysis GO:0019835 24 21 0,000 0,11955911 0,15582839 ! vasodilation GO:0042311 39 21 0,000 0,11955911 0,15574403 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11955911 0,15565975 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11955911 0,15557556 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11955911 0,15549147 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,11955911 0,15540746 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,11955911 0,15532355 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11955911 0,15523973 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11955911 0,155156 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11955911 0,15507235 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11955911 0,1549888 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11955911 0,15490534 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11955911 0,15482197 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11955911 0,15473869 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11955911 0,15465549 ! collagen catabolic process GO:0030574 28 21 0,000 0,11955911 0,15457239 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11955911 0,15448938 ! gut development GO:0048565 39 21 0,000 0,11955911 0,15440645 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,12070676 0,15580497 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12488341 0,16110965 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12488341 0,16102331 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12488341 0,16093706 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12488341 0,16085091 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12488341 0,16076484 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,12488341 0,16067887 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12488341 0,16059299 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12488341 0,16050721 ! regeneration GO:0031099 41 22 0,000 0,12488341 0,16042151 ! keratinization GO:0031424 28 22 0,000 0,12488341 0,16033591 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12488341 0,1602504 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12488341 0,16016497 ! sensory perception of taste GO:0050909 28 22 0,000 0,12488341 0,16007964 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12488341 0,1599944 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12488341 0,15990926 ! vacuolar transport GO:0007034 36 22 0,000 0,12488341 0,1598242 ! lysosome organization GO:0007040 41 22 0,000 0,12488341 0,15973923 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12488341 0,15965435 ! fucose metabolic process GO:0006004 39 22 0,000 0,12488341 0,15956957 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12488341 0,15948487 ! ureteric bud development GO:0001657 43 22 0,000 0,12488341 0,15940026 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12488341 0,15931574 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12488341 0,15923132 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12488341 0,15914698 ! sarcomere organization GO:0045214 30 22 0,000 0,12488341 0,15906273 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12488341 0,15897857 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12488341 0,1588945 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,12488341 0,15881051 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,12488341 0,15872662 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,13017569 0,16536575 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,13017569 0,16527848 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13017569 0,16519131 ! gluconeogenesis GO:0006094 33 23 0,000 0,13017569 0,16510423 ! viral genome replication GO:0019079 41 23 0,000 0,13017569 0,16501724 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13017569 0,16493034 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13017569 0,16484354 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13017569 0,16475682 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,13017569 0,1646702 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13017569 0,16458367 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,13017569 0,16449723 ! response to ethanol GO:0045471 46 23 0,000 0,13017569 0,16441088 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13017569 0,16432462 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13017569 0,16423845 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13017569 0,16415237 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13017569 0,16406638 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13017569 0,16398048 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13017569 0,16389467 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,13017569 0,16380895 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,13017569 0,16372333 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13017569 0,16363779 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13017569 0,16355233 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13017569 0,16346697 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13017569 0,1633817 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13017569 0,16329652 ! fatty acid transport GO:0015908 44 23 0,000 0,13017569 0,16321142 ! platelet activation GO:0030168 37 23 0,000 0,13017569 0,16312642 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,13017569 0,1630415 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13017569 0,16295667 ! hormone transport GO:0009914 40 23 0,000 0,13017569 0,16287193 ! cell-cell recognition GO:0009988 25 23 0,000 0,13017569 0,16278728 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13017569 0,16270271 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13017569 0,16261824 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,13017569 0,16253385 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,13543615 0,16901419 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13543615 0,16892658 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,13543615 0,16883905 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13543615 0,16875161 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13543615 0,16866427 ! vesicle docking GO:0048278 47 24 0,000 0,13543615 0,16857701 ! spinal cord development GO:0021510 47 24 0,000 0,13543615 0,16848985 ! vacuole organization GO:0007033 43 24 0,000 0,13543615 0,16840277 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13543615 0,16831579 ! digestive system process GO:0022600 39 24 0,000 0,13543615 0,16822889 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13543615 0,16814209 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13543615 0,16805537 ! regulation of behavior GO:0050795 43 24 0,000 0,13543615 0,16796875 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13543615 0,16788221 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13543615 0,16779576 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13543615 0,1677094 ! pallium development GO:0021543 49 24 0,000 0,13543615 0,16762313 ! pentose metabolic process GO:0019321 35 24 0,000 0,13543615 0,16753695 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13543615 0,16745086 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13543615 0,16736485 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13543615 0,16727894 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13543615 0,16719311 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13543615 0,16710737 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13543615 0,16702172 ! regulation of amine transport GO:0051952 40 24 0,000 0,13543615 0,16693615 ! protein tetramerization GO:0051262 52 24 0,000 0,13543615 0,16685067 ! myelination GO:0042552 45 25 0,000 0,14066496 0,17320363 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14066496 0,17311503 ! phototransduction GO:0007602 33 25 0,000 0,14066496 0,17302653 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14066496 0,17293811 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,14066496 0,17284979 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,14066496 0,17276156 ! sperm motility GO:0030317 31 25 0,000 0,14066496 0,17267341 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14066496 0,17258536 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,14066496 0,17249739 ! chromosome condensation GO:0030261 45 25 0,000 0,14066496 0,17240952 ! osteoblast differentiation GO:0001649 60 25 0,000 0,14066496 0,17232174 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,14066496 0,17223404 ! neural crest cell development GO:0014032 54 25 0,000 0,14066496 0,17214643 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,14066496 0,17205892 ! negative regulation of cell development GO:0010721 73 25 0,000 0,14066496 0,17197149 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14066496 0,17188415 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14066496 0,1717969 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,14066496 0,17170973 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,14066496 0,17162266 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14066496 0,17153568 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,14066496 0,17144878 ! immunoglobulin production GO:0002377 55 25 0,000 0,14066496 0,17136197 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14066496 0,17127525 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14066496 0,17118861 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14066496 0,17110207 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14066496 0,17101561 ! telomere organization GO:0032200 43 25 0,000 0,14066496 0,17092924 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,14066496 0,17084295 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,14066496 0,17075675 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14586232 0,17697667 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14586232 0,17688747 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14586232 0,17679836 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14586232 0,17670933 ! initiation of viral infection GO:0019059 57 26 0,000 0,14586232 0,1766204 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14586232 0,17653156 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14586232 0,1764428 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14586232 0,17635414 ! molting cycle process GO:0022404 50 26 0,000 0,14586232 0,17626556 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,14586232 0,17617708 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14586232 0,17608868 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14586232 0,17600037 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14586232 0,17591215 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14586232 0,17582402 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14586232 0,17573597 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14586232 0,17564802 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,14586232 0,17556015 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14586232 0,17547237 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14586232 0,17538468 ! blastocyst development GO:0001824 49 26 0,000 0,14586232 0,17529707 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14586232 0,17520955 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14586232 0,17512212 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14586232 0,17503478 ! neuron fate commitment GO:0048663 48 27 0,000 0,15102842 0,18114375 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,15102842 0,1810535 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,15102842 0,18096333 ! iron ion transport GO:0006826 59 27 0,000 0,15102842 0,18087326 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,15102842 0,18078327 ! protein amino acid acylation GO:0043543 55 27 0,000 0,15102842 0,18069337 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,15102842 0,18060356 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,15102842 0,18051384 ! fat cell differentiation GO:0045444 50 27 0,000 0,15102842 0,18042422 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,15102842 0,18033467 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,15102842 0,18024522 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,15102842 0,18015586 ! autophagy GO:0006914 41 27 0,000 0,15102842 0,18006659 ! male gonad development GO:0008584 44 27 0,000 0,15102842 0,1799774 ! response to toxin GO:0009636 47 27 0,000 0,15102842 0,1798883 ! primary neural tube formation GO:0014020 51 27 0,000 0,15102842 0,17979929 ! base-excision repair GO:0006284 41 27 0,000 0,15102842 0,17971037 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,15102842 0,17962154 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,15102842 0,17953279 ! glutathione metabolic process GO:0006749 39 27 0,000 0,15102842 0,17944413 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,15102842 0,17935556 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,15102842 0,17926708 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,15102842 0,17917868 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15616344 0,18517951 ! circadian rhythm GO:0007623 50 28 0,000 0,15616344 0,18508829 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15616344 0,18499716 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15616344 0,18490612 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,15616344 0,18481517 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15616344 0,1847243 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,15616344 0,18463353 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15616344 0,18454285 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15616344 0,18445225 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15616344 0,18436174 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15616344 0,18427133 ! synaptogenesis GO:0007416 42 28 0,000 0,15616344 0,184181 ! lipid oxidation GO:0034440 43 28 0,000 0,15616344 0,18409076 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15616344 0,1840006 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15616344 0,18391054 ! translational initiation GO:0006413 65 29 0,000 0,16126757 0,18982866 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,16126757 0,18973583 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,16126757 0,1896431 ! regulation of pH GO:0006885 43 29 0,000 0,16126757 0,18955045 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,16126757 0,1894579 ! catechol metabolic process GO:0009712 54 29 0,000 0,16126757 0,18936544 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,16126757 0,18927306 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,16126757 0,18918078 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,16126757 0,18908859 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,16126757 0,18899648 ! cell fate determination GO:0001709 60 29 0,000 0,16126757 0,18890447 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,16126757 0,18881254 ! detection of light stimulus GO:0009583 38 29 0,000 0,16126757 0,18872071 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,16126757 0,18862896 ! tissue homeostasis GO:0001894 48 29 0,000 0,16126757 0,18853731 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,166341 0,19437418 ! zinc ion transport GO:0006829 45 30 0,000 0,166341 0,19427983 ! membrane docking GO:0022406 61 30 0,000 0,166341 0,19418556 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,166341 0,19409139 ! cell junction assembly GO:0034329 78 30 0,000 0,166341 0,19399731 ! regulation of innate immune response GO:0045088 51 30 0,000 0,166341 0,19390332 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,166341 0,19380942 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,166341 0,19371561 ! phospholipid transport GO:0015914 51 30 0,000 0,166341 0,19362189 ! ensheathment of neurons GO:0007272 57 30 0,000 0,166341 0,19352826 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,166341 0,19343472 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,166341 0,19334128 ! eye morphogenesis GO:0048592 60 30 0,000 0,166341 0,19324792 ! response to heat GO:0009408 50 30 0,000 0,166341 0,19315466 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,17138391 0,19891446 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,17138391 0,19881855 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,17138391 0,19872274 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,17138391 0,19862701 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,17138391 0,19853138 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,17138391 0,19843584 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,17138391 0,19834039 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,17138391 0,19824504 ! ovulation cycle process GO:0022602 49 31 0,000 0,17138391 0,19814977 ! peptide transport GO:0015833 55 31 0,000 0,17138391 0,1980546 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,17138391 0,19795952 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,17138391 0,19786453 ! mesoderm formation GO:0001707 69 31 0,000 0,17138391 0,19776963 ! natural killer cell activation GO:0030101 45 31 0,000 0,17138391 0,19767482 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,17138391 0,1975801 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,17138391 0,19748548 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,17138391 0,19739094 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17639647 0,20306695 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17639647 0,20296983 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17639647 0,20287281 ! cholesterol transport GO:0030301 56 32 0,000 0,17639647 0,20277588 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17639647 0,20267904 ! spliceosome assembly GO:0000245 67 32 0,000 0,17639647 0,2025823 ! spindle organization GO:0007051 46 32 0,000 0,17639647 0,20248565 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17639647 0,20238909 ! metanephros development GO:0001656 74 32 0,000 0,17639647 0,20229262 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17639647 0,20219625 ! response to ionizing radiation GO:0010212 65 32 0,000 0,17639647 0,20209996 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17639647 0,20200377 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17639647 0,20190767 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17639647 0,20181166 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,17639647 0,20171574 ! ovulation cycle GO:0042698 51 32 0,000 0,17639647 0,20161991 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17639647 0,20152418 ! hindbrain development GO:0030902 61 32 0,000 0,17639647 0,20142853 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,17639647 0,20133298 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17639647 0,20123751 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,17639647 0,20114214 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,18137889 0,20672553 ! post-embryonic development GO:0009791 69 33 0,000 0,18137889 0,20662765 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,18137889 0,20652986 ! protein targeting to membrane GO:0006612 68 33 0,000 0,18137889 0,20643217 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,18137889 0,20633456 ! ceramide metabolic process GO:0006672 64 33 0,000 0,18137889 0,20623705 ! formation of primary germ layer GO:0001704 72 33 0,000 0,18137889 0,20613963 ! cell fate specification GO:0001708 52 33 0,000 0,18137889 0,2060423 ! sterol transport GO:0015918 57 33 0,000 0,18137889 0,20594507 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,18137889 0,20584792 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,18137889 0,20575087 ! adult locomotory behavior GO:0008344 59 33 0,000 0,18137889 0,20565391 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,18137889 0,20555704 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18633132 0,21107022 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,18633132 0,2109709 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18633132 0,21087166 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,18633132 0,21077252 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,18633132 0,21067348 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18633132 0,21057452 ! mismatch repair GO:0006298 46 34 0,000 0,18633132 0,21047566 ! spermatid development GO:0007286 63 34 0,000 0,18633132 0,21037689 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18633132 0,21027822 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,18633132 0,21017963 ! placenta development GO:0001890 53 34 0,000 0,18633132 0,21008114 ! regulation of muscle development GO:0048634 70 35 0,000 0,19125396 0,21553022 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,19125396 0,21542932 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,19125396 0,21532851 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,19125396 0,21522779 ! odontogenesis GO:0042476 66 35 0,000 0,19125396 0,21512717 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,19125396 0,21502665 ! female gonad development GO:0008585 58 35 0,000 0,19125396 0,21492621 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,19125396 0,21482587 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,19125396 0,21472563 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,19125396 0,21462548 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,19125396 0,21452542 ! neural tube formation GO:0001841 67 35 0,000 0,19125396 0,21442545 ! vesicle localization GO:0051648 64 35 0,000 0,19125396 0,21432558 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,19614698 0,21970653 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,19614698 0,21960429 ! cell junction organization GO:0034330 86 36 0,000 0,19614698 0,21950215 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19614698 0,2194001 ! positive regulation of cell development GO:0010720 80 36 0,000 0,19614698 0,21929815 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,19614698 0,2191963 ! regulation of proteolysis GO:0030162 72 36 0,000 0,19614698 0,21909453 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19614698 0,21899287 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19614698 0,21889129 ! aerobic respiration GO:0009060 55 36 0,000 0,19614698 0,21878981 ! embryonic organ development GO:0048568 57 36 0,000 0,19614698 0,21868843 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19614698 0,21858714 ! RNA export from nucleus GO:0006405 56 37 0,000 0,20101055 0,22390342 ! meiosis I GO:0007127 65 37 0,000 0,20101055 0,22379981 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,20101055 0,2236963 ! sister chromatid segregation GO:0000819 58 37 0,000 0,20101055 0,22359288 ! organic anion transport GO:0015711 68 37 0,000 0,20101055 0,22348955 ! tissue remodeling GO:0048771 76 37 0,000 0,20101055 0,22338632 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,20101055 0,22328319 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,20101055 0,22318015 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,20101055 0,22307721 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,20101055 0,22297436 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,20101055 0,22287161 ! pigment metabolic process GO:0042440 80 37 0,000 0,20101055 0,22276895 ! spermatid differentiation GO:0048515 66 37 0,000 0,20101055 0,22266639 ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,20584486 0,22791659 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20584486 0,22781175 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,20584486 0,22770701 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20584486 0,22760236 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,20584486 0,22749782 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,20584486 0,22739336 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,20584486 0,22728901 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,20584486 0,22718474 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20584486 0,22708058 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,20584486 0,22697651 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20584486 0,22687253 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,20584486 0,22676866 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,20584486 0,22666487 ! glucan metabolic process GO:0044042 62 38 0,000 0,20584486 0,22656118 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,21065008 0,23174399 ! mammary gland development GO:0030879 86 39 0,000 0,21065008 0,23163807 ! learning GO:0007612 77 39 0,000 0,21065008 0,23153225 ! organic ether metabolic process GO:0018904 55 39 0,000 0,21065008 0,23142653 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,21065008 0,23132091 ! segmentation GO:0035282 67 39 0,000 0,21065008 0,23121538 ! ion transmembrane transport GO:0034220 66 39 0,000 0,21065008 0,23110994 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,21065008 0,23100461 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,21065008 0,23089936 ! RNA modification GO:0009451 57 39 0,000 0,21065008 0,23079422 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,21065008 0,23068917 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21542639 0,23581251 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21542639 0,23570527 ! feeding behavior GO:0007631 59 40 0,000 0,21542639 0,23559813 ! mesenchymal cell development GO:0014031 87 40 0,000 0,21542639 0,23549109 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,21542639 0,23538415 ! cytokinesis GO:0000910 72 40 0,000 0,21542639 0,2352773 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,22017395 0,24035323 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,22017395 0,24024423 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,22017395 0,24013532 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,22017395 0,24002652 ! T cell differentiation GO:0030217 81 41 0,000 0,22017395 0,23991781 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,22017395 0,2398092 ! polyol metabolic process GO:0019751 66 41 0,000 0,22017395 0,23970069 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,22017395 0,23959228 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,22489294 0,24461682 ! regulation of tube size GO:0035150 71 42 0,000 0,22489294 0,24450629 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22489294 0,24439585 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,22489294 0,24428551 ! neuron migration GO:0001764 79 42 0,000 0,22489294 0,24417528 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,22958353 0,2491556 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22958353 0,24904327 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22958353 0,24893104 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,22958353 0,24881891 ! glucose transport GO:0015758 65 43 0,000 0,22958353 0,24870688 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,22958353 0,24859495 ! neural tube development GO:0021915 77 43 0,000 0,22958353 0,24848312 ! phagocytosis GO:0006909 90 43 0,000 0,22958353 0,24837139 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22958353 0,24825976 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23424589 0,25318761 ! hexose transport GO:0008645 67 44 0,000 0,23424589 0,25307392 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,23424589 0,25296033 ! male sex differentiation GO:0046661 76 44 0,000 0,23424589 0,25284684 ! double-strand break repair GO:0006302 81 44 0,000 0,23424589 0,25273346 ! B cell differentiation GO:0030183 107 44 0,000 0,23424589 0,25262017 ! developmental growth GO:0048589 82 44 0,000 0,23424589 0,25250699 ! leukocyte migration GO:0050900 68 45 0,000 0,23888019 0,25738725 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,23888019 0,25727204 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,23888019 0,25715693 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,23888019 0,25704192 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,23888019 0,25692701 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,23888019 0,25681221 ! cell growth GO:0016049 84 45 0,000 0,23888019 0,25669751 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,24348659 0,26153069 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,24348659 0,26141399 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,24348659 0,26129739 ! positive regulation of defense response GO:0031349 76 47 0,000 0,24806527 0,26609231 ! response to calcium ion GO:0051592 81 47 0,000 0,24806527 0,26597373 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,24806527 0,26585525 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24806527 0,26573688 ! JNK cascade GO:0007254 91 47 0,000 0,24806527 0,26561862 ! mitochondrial transport GO:0006839 82 48 0,000 0,25261639 0,27037146 ! Notch signaling pathway GO:0007219 96 48 0,000 0,25261639 0,27025124 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,25261639 0,27013113 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25261639 0,27001112 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,25261639 0,26989122 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,25261639 0,26977143 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,25261639 0,26965174 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25714011 0,27435881 ! regulation of action potential GO:0001508 95 49 0,000 0,25714011 0,27423719 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,25714011 0,27411569 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25714011 0,27399429 ! regulation of ion transport GO:0043269 77 49 0,000 0,25714011 0,273873 ! peptide metabolic process GO:0006518 76 49 0,000 0,25714011 0,27375182 ! response to temperature stimulus GO:0009266 76 49 0,000 0,25714011 0,27363074 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,25714011 0,27350977 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,25714011 0,27338891 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25714011 0,27326816 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,2616366 0,27792391 ! neuromuscular process GO:0050905 99 50 0,000 0,2616366 0,27780127 ! inner ear development GO:0048839 79 50 0,000 0,2616366 0,27767872 ! histone modification GO:0016570 91 50 0,000 0,2616366 0,27755629 ! viral infectious cycle GO:0019058 99 51 0,000 0,26610603 0,28217325 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,26610603 0,28204894 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,26610603 0,28192475 ! chromatin remodeling GO:0006338 109 51 0,000 0,26610603 0,28180066 ! vesicle organization GO:0016050 107 51 0,000 0,26610603 0,28167668 ! regulation of cell shape GO:0008360 125 51 0,000 0,26610603 0,28155281 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,26610603 0,28142905 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,27054854 0,28600167 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,27054854 0,28587606 ! membrane fusion GO:0006944 110 52 0,000 0,27054854 0,28575057 ! covalent chromatin modification GO:0016569 101 52 0,000 0,27054854 0,28562518 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,27054854 0,28549991 ! amino acid activation GO:0043038 92 52 0,000 0,27054854 0,28537474 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,27054854 0,28524969 ! synapse organization GO:0050808 85 52 0,000 0,27054854 0,28512475 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,27496431 0,28965155 ! RNA catabolic process GO:0006401 93 53 0,000 0,27496431 0,28952479 ! regulation of translational initiation GO:0006446 82 53 0,000 0,27496431 0,28939814 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,27496431 0,2892716 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27496431 0,28914517 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,2793535 0,29363238 ! cell recognition GO:0008037 85 54 0,000 0,2793535 0,29350416 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,2793535 0,29337605 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,2793535 0,29324805 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,2793535 0,29312016 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,28371626 0,29756814 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,28371626 0,29743848 ! aging GO:0007568 103 55 0,000 0,28371626 0,29730894 ! gastrulation GO:0007369 112 55 0,000 0,28371626 0,2971795 ! heart morphogenesis GO:0003007 97 55 0,000 0,28371626 0,29705018 ! nuclear export GO:0051168 97 55 0,000 0,28371626 0,29692098 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,28371626 0,29679188 ! sensory perception of smell GO:0007608 80 56 0,000 0,28805275 0,30119727 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28805275 0,30106643 ! proton transport GO:0015992 94 56 0,000 0,28805275 0,3009357 ! hydrogen transport GO:0006818 97 58 0,000 0,29664756 0,3097804 ! regulation of endocytosis GO:0030100 91 58 0,000 0,29664756 0,309646 ! adult behavior GO:0030534 99 58 0,000 0,29664756 0,30951172 ! positive regulation of secretion GO:0051047 95 59 0,000 0,30090619 0,31381894 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,30090619 0,31368297 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,30090619 0,31354712 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,30513918 0,31782029 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,30513918 0,31768276 ! regulation of heart contraction GO:0008016 110 60 0,000 0,30513918 0,31754536 ! camera-type eye development GO:0043010 116 60 0,000 0,30513918 0,31740807 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,30513918 0,3172709 ! kidney development GO:0001822 122 60 0,000 0,30513918 0,31713385 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30934667 0,32136792 ! mesoderm development GO:0007498 119 61 0,000 0,30934667 0,32122922 ! tRNA processing GO:0008033 89 61 0,000 0,30934667 0,32109064 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30934667 0,32095218 ! viral reproductive process GO:0022415 126 62 0,000 0,31352883 0,32515102 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,31352883 0,32501093 ! gonad development GO:0008406 98 62 0,000 0,31352883 0,32487096 ! regulation of mitosis GO:0007088 105 63 0,000 0,3176858 0,32903661 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3176858 0,32889502 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,3176858 0,32875356 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,32181774 0,33288627 ! cell redox homeostasis GO:0045454 102 64 0,000 0,32181774 0,33274322 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,32181774 0,33260029 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,32181774 0,33245748 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32592479 0,33655581 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,32592479 0,33641143 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,32592479 0,33626717 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,3300071 0,34033308 ! secondary metabolic process GO:0019748 116 66 0,000 0,3300071 0,34018727 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,33406482 0,34422268 ! lung development GO:0030324 144 67 0,000 0,33406482 0,34407533 ! chromosome segregation GO:0007059 113 67 0,000 0,33406482 0,3439281 ! amino acid transport GO:0006865 125 68 0,000 0,33809811 0,34793159 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33809811 0,34778283 ! viral reproduction GO:0016032 134 68 0,000 0,33809811 0,34763421 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,3421071 0,35160602 ! urogenital system development GO:0001655 137 69 0,000 0,3421071 0,35145588 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,3421071 0,35130588 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,3421071 0,35115601 ! antigen processing and presentation GO:0019882 104 69 0,000 0,3421071 0,35100626 ! appendage morphogenesis GO:0035107 135 70 0,000 0,34609194 0,3549434 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 0,000 0,34609194 0,35479216 ! reproductive structure development GO:0048608 113 71 0,000 0,35005278 0,35869974 ! appendage development GO:0048736 136 71 0,000 0,35005278 0,35854703 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,35005278 0,35839446 ! carbohydrate transport GO:0008643 110 72 0,000 0,35398975 0,3622711 ! respiratory system development GO:0060541 153 72 0,000 0,35398975 0,36211707 ! regulation of blood pressure GO:0008217 125 73 0,000 0,35790301 0,36596458 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,35790301 0,36580911 ! axon guidance GO:0007411 139 73 0,000 0,35790301 0,36565378 ! fertilization GO:0009566 90 73 0,000 0,35790301 0,36549858 ! transition metal ion transport GO:0000041 126 74 0,000 0,3617927 0,36931405 ! eye development GO:0001654 143 74 0,000 0,3617927 0,36915743 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36565895 0,37294422 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,36565895 0,3727862 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,36565895 0,3726283 ! rhythmic process GO:0048511 128 75 0,000 0,36565895 0,37247054 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,36565895 0,37231292 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,3695019 0,37606666 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,3695019 0,37590764 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,3695019 0,37574876 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3733217 0,37947276 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,37711849 0,38317022 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,3808924 0,38684133 ! response to metal ion GO:0010038 140 80 0,000 0,38464357 0,39048625 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,38464357 0,39032156 ! response to hypoxia GO:0001666 171 81 0,000 0,38837213 0,39393901 ! digestion GO:0007586 112 81 0,000 0,38837213 0,39377301 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,38837213 0,39360714 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,38837213 0,39344141 ! response to nutrient GO:0007584 125 82 0,000 0,39207822 0,39702871 ! response to oxygen levels GO:0070482 176 83 0,000 0,39576199 0,40059038 ! response to unfolded protein GO:0006986 131 85 0,000 0,40306304 0,40780895 ! nucleosome assembly GO:0006334 122 85 0,000 0,40306304 0,40763753 ! amine biosynthetic process GO:0009309 138 86 0,000 0,4066806 0,41112333 ! response to inorganic substance GO:0010035 153 86 0,000 0,4066806 0,41095066 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,4066806 0,41077814 ! chromatin assembly GO:0031497 124 86 0,000 0,4066806 0,41060576 ! tube morphogenesis GO:0035239 176 86 0,000 0,4066806 0,41043352 ! amine transport GO:0015837 155 86 0,000 0,4066806 0,41026143 ! cellular respiration GO:0045333 135 88 0,000 0,41385044 0,41731943 ! gland development GO:0048732 206 88 0,000 0,41385044 0,4171446 ! cellular defense response GO:0006968 114 89 0,000 0,41740298 0,42054923 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,41740298 0,42037319 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,4209341 0,42375207 ! sex differentiation GO:0007548 145 90 0,000 0,4209341 0,42357484 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,4209341 0,42339776 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,42444394 0,42674974 ! regulation of defense response GO:0031347 149 92 0,000 0,42793263 0,43007765 ! nucleosome organization GO:0034728 138 92 0,000 0,42793263 0,42989808 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,42793263 0,42971866 ! vitamin metabolic process GO:0006766 139 92 0,000 0,42793263 0,42953938 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,43140028 0,43283948 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,43484703 0,43611586 ! female pregnancy GO:0007565 164 94 0,000 0,43484703 0,43593414 ! forebrain development GO:0030900 188 95 0,000 0,43827299 0,43918568 ! leukocyte differentiation GO:0002521 202 96 0,000 0,44167831 0,44241383 ! mRNA transport GO:0051028 169 96 0,000 0,44167831 0,44222972 ! protein ubiquitination GO:0016567 217 97 0,000 0,44506309 0,44543336 ! hormone metabolic process GO:0042445 157 97 0,000 0,44506309 0,44524815 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,45177155 0,45177155