pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/605-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 224 98 7,000 7,333E-08 1,791E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 1,97E-07 2,406E-04 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 3,000 1,977E-06 1,61E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 4,826E-06 2,948E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,333E-05 6,513E-03 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 1,396E-05 5,686E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 4,000 1,568E-05 5,473E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 1,897E-05 5,792E-03 ! regulation of chemokine biosynthetic process GO:0045073 12 10 2,000 1,897E-05 5,148E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 3,449E-05 8,426E-03 ! regulation of chemokine production GO:0032642 18 13 2,000 4,466E-05 9,918E-03 ! actin filament organization GO:0007015 167 72 4,000 4,902E-05 9,981E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 5,603E-05 0,01052865 ! release of cytochrome c from mitochondria GO:0001836 31 14 2,000 5,661E-05 9,878E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 2,000 7,047E-05 0,01147746 ! activation of protein kinase activity GO:0032147 170 80 4,000 8,13E-05 0,01241351 ! signal complex assembly GO:0007172 47 17 2,000 1,045E-04 0,0150131 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,045E-04 0,01417904 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 1,085E-04 0,01395101 ! response to insulin stimulus GO:0032868 98 47 3,000 1,303E-04 0,01591156 ! G1 phase of mitotic cell cycle GO:0000080 39 19 2,000 1,477E-04 0,01717914 ! regulation of postsynaptic membrane potential GO:0060078 38 19 2,000 1,477E-04 0,01639827 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 1,534E-04 0,01629562 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,73E-04 0,01761304 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 2,011E-04 0,01964702 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 3,000 2,084E-04 0,01958497 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 2,084E-04 0,0188596 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! actin polymerization or depolymerization GO:0008154 52 22 2,000 2,319E-04 0,02022985 ! apoptotic nuclear changes GO:0030262 34 22 2,000 2,319E-04 0,01953227 ! G1 phase GO:0051318 44 22 2,000 2,319E-04 0,01888119 ! response to UV GO:0009411 120 55 3,000 2,407E-04 0,01896873 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,656E-04 0,0202742 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 1,000 2,962E-04 0,02192817 ! female meiosis GO:0007143 10 5 1,000 2,962E-04 0,02128322 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 2,962E-04 0,02067513 ! skeletal myofibril assembly GO:0014866 12 5 1,000 2,962E-04 0,02010082 ! cardiac muscle fiber development GO:0048739 12 5 1,000 2,962E-04 0,01955756 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,962E-04 0,01904288 ! valine metabolic process GO:0006573 12 5 1,000 2,962E-04 0,0185546 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,962E-04 0,01809074 ! B cell homeostasis GO:0001782 13 5 1,000 2,962E-04 0,0176495 ! protein insertion into membrane GO:0051205 17 5 1,000 2,962E-04 0,01722928 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 3,023E-04 0,01717366 ! membrane depolarization GO:0051899 45 24 2,000 3,023E-04 0,01678335 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 3,023E-04 0,01641039 ! DNA catabolic process GO:0006308 94 60 3,000 3,369E-04 0,01789109 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 3,421E-04 0,01778267 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 3,421E-04 0,0174122 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 3,852E-04 0,01920396 ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 4,315E-04 0,02108363 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 4,315E-04 0,02067023 ! regulation of interferon-beta production GO:0032648 8 6 1,000 4,427E-04 0,02079846 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 1,000 4,427E-04 0,02040604 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 4,427E-04 0,02002815 ! early endosome to late endosome transport GO:0045022 16 6 1,000 4,427E-04 0,019664 ! response to exogenous dsRNA GO:0043330 13 6 1,000 4,427E-04 0,01931286 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 1,000 4,427E-04 0,01897404 ! positive regulation of actin filament polymerization GO:0030838 11 6 1,000 4,427E-04 0,0186469 ! hyperosmotic response GO:0006972 10 6 1,000 4,427E-04 0,01833085 ! neuron apoptosis GO:0051402 15 6 1,000 4,427E-04 0,01802533 ! interaction with symbiont GO:0051702 14 6 1,000 4,427E-04 0,01772984 ! positive regulation of cytokine production during immune response GO:0002720 11 6 1,000 4,427E-04 0,01744387 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,427E-04 0,01716698 ! negative regulation of B cell activation GO:0050869 14 6 1,000 4,427E-04 0,01689875 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 4,814E-04 0,01809417 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 4,814E-04 0,01782002 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 3,000 5,437E-04 0,01982575 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 5,747E-04 0,02064807 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 3,000 5,747E-04 0,02034882 ! neurotransmitter secretion GO:0007269 55 30 2,000 5,918E-04 0,02065535 ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 5,918E-04 0,02036443 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 2,000 5,918E-04 0,02008159 ! negative regulation of kinase activity GO:0033673 145 70 3,000 6,07E-04 0,02031272 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 6,175E-04 0,02038725 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,175E-04 0,02011542 ! neuron remodeling GO:0016322 16 7 1,000 6,175E-04 0,01985074 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 1,000 6,175E-04 0,01959294 ! induction of apoptosis by oxidative stress GO:0008631 9 7 1,000 6,175E-04 0,01934175 ! centrosome duplication GO:0051298 14 7 1,000 6,175E-04 0,01909691 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 1,000 6,175E-04 0,0188582 ! negative regulation of osteoclast differentiation GO:0045671 10 7 1,000 6,175E-04 0,01862539 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 6,526E-04 0,01944326 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 3,000 6,753E-04 0,01987551 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 3,000 6,753E-04 0,01963889 ! response to mechanical stimulus GO:0009612 60 32 2,000 7,172E-04 0,02061415 ! negative regulation of transferase activity GO:0051348 155 74 3,000 7,488E-04 0,02127182 ! negative regulation of protein transport GO:0051224 74 33 2,000 7,858E-04 0,02206518 ! regulation of transcription factor activity GO:0051090 137 75 3,000 7,876E-04 0,02186621 GO:0090046|regulation of transcription regulator activity, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 8,204E-04 0,02251995 ! regulation of interferon-alpha production GO:0032647 11 8 1,000 8,204E-04 0,02226973 ! succinate metabolic process GO:0006105 17 8 1,000 8,204E-04 0,022025 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,204E-04 0,0217856 ! negative regulation of muscle cell differentiation GO:0051148 17 8 1,000 8,204E-04 0,02155135 ! L-phenylalanine metabolic process GO:0006558 12 8 1,000 8,204E-04 0,02132208 GO:0006559|L-phenylalanine catabolic process, ! Schwann cell differentiation GO:0014037 21 8 1,000 8,204E-04 0,02109764 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 1,000 8,204E-04 0,02087787 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 8,204E-04 0,02066263 ! positive regulation of ligase activity GO:0051351 130 77 3,000 8,695E-04 0,02167606 ! positive regulation of lymphocyte activation GO:0051251 142 78 3,000 9,126E-04 0,02252088 ! negative regulation of secretion GO:0051048 68 35 2,000 9,351E-04 0,02284351 ! calcium-mediated signaling GO:0019722 67 35 2,000 9,351E-04 0,02261734 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 3,000 9,572E-04 0,02292649 ! negative regulation of DNA binding GO:0043392 67 36 2,000 1,016E-03 0,02409713 ! regulation of activated T cell proliferation GO:0046006 19 9 1,000 1,051E-03 0,02468866 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,051E-03 0,02445353 ! regulation of type I interferon production GO:0032479 12 9 1,000 1,051E-03 0,02422284 ! Rac protein signal transduction GO:0016601 20 9 1,000 1,051E-03 0,02399646 ! receptor clustering GO:0043113 20 9 1,000 1,051E-03 0,02377427 ! negative regulation of cytokine secretion GO:0050710 16 9 1,000 1,051E-03 0,02355616 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,051E-03 0,02334201 ! mitochondrion localization GO:0051646 18 9 1,000 1,051E-03 0,02313172 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,101E-03 0,02401922 ! regulation of ligase activity GO:0051340 147 84 3,000 1,203E-03 0,02601667 ! negative regulation of transport GO:0051051 164 85 3,000 1,257E-03 0,02694713 ! negative regulation of binding GO:0051100 71 39 2,000 1,285E-03 0,02729363 ! positive regulation of leukocyte proliferation GO:0070665 70 39 2,000 1,285E-03 0,02705834 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,309E-03 0,02733284 ! elastic fiber assembly GO:0048251 17 10 1,000 1,309E-03 0,02710121 ! phosphagen metabolic process GO:0006599 17 10 1,000 1,309E-03 0,02687347 GO:0006600|creatine metabolic process, ! response to dsRNA GO:0043331 23 10 1,000 1,309E-03 0,02664952 ! positive regulation of cell activation GO:0050867 161 86 3,000 1,313E-03 0,0265137 GO:0002696|positive regulation of leukocyte activation, ! nucleus organization GO:0006997 73 40 2,000 1,383E-03 0,02770196 ! gliogenesis GO:0042063 91 41 2,000 1,487E-03 0,02952697 ! regulation of DNA binding GO:0051101 167 89 3,000 1,491E-03 0,02937059 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,594E-03 0,03115597 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,594E-03 0,0309087 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 1,000 1,594E-03 0,03066532 ! positive regulation of T cell mediated immunity GO:0002711 26 11 1,000 1,594E-03 0,03042575 ! DNA methylation GO:0006306 19 11 1,000 1,594E-03 0,03018989 GO:0006305|DNA alkylation, ! regulation of osteoclast differentiation GO:0045670 17 11 1,000 1,594E-03 0,02995766 ! positive regulation of JNK cascade GO:0046330 23 11 1,000 1,594E-03 0,02972898 ! oocyte development GO:0048599 20 11 1,000 1,594E-03 0,02950376 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,707E-03 0,03135983 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 1,707E-03 0,0311258 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 3,000 1,753E-03 0,03171662 GO:0010498|proteasomal protein catabolic process, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,906E-03 0,03423929 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,906E-03 0,03398937 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,906E-03 0,03374307 ! tyrosine metabolic process GO:0006570 19 12 1,000 1,906E-03 0,03350031 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 1,000 1,906E-03 0,03326102 ! cranial nerve development GO:0021545 23 12 1,000 1,906E-03 0,03302513 ! T cell homeostasis GO:0043029 28 12 1,000 1,906E-03 0,03279256 ! oocyte differentiation GO:0009994 21 12 1,000 1,906E-03 0,03256324 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,906E-03 0,03233711 GO:0042130|negative regulation of T cell proliferation, ! lamellipodium assembly GO:0030032 24 12 1,000 1,906E-03 0,03211409 ! localization within membrane GO:0051668 26 12 1,000 1,906E-03 0,03189413 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,947E-03 0,03236309 ! keratinocyte differentiation GO:0030216 81 45 2,000 1,947E-03 0,03214442 ! maintenance of location in cell GO:0051651 101 45 2,000 1,947E-03 0,03192869 ! regulation of T cell activation GO:0050863 175 96 3,000 1,969E-03 0,0320664 ! transcription initiation GO:0006352 171 97 3,000 2,045E-03 0,03308343 ! endocrine pancreas development GO:0031018 25 13 1,000 2,245E-03 0,03607468 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 1,000 2,245E-03 0,0358389 ! regulation of cytokine production during immune response GO:0002718 25 13 1,000 2,245E-03 0,03560618 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,245E-03 0,03537646 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 2,245E-03 0,03514969 ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 2,245E-03 0,03492581 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,245E-03 0,03470476 ! cellular component disassembly GO:0022411 89 48 2,000 2,345E-03 0,03603313 ! negative regulation of protein secretion GO:0050709 30 14 1,000 2,609E-03 0,03983872 ! positive regulation of protein polymerization GO:0032273 27 14 1,000 2,609E-03 0,03959128 ! epidermal cell differentiation GO:0009913 87 50 2,000 2,636E-03 0,03975658 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 1,000 3E-03 0,04495923 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 3E-03 0,04468509 ! regulation of T cell mediated immunity GO:0002709 36 15 1,000 3E-03 0,04441427 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3E-03 0,04414671 ! cell killing GO:0001906 32 15 1,000 3E-03 0,04388236 ! lymphocyte homeostasis GO:0002260 33 15 1,000 3E-03 0,04362116 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 2,000 3,283E-03 0,04746109 ! response to osmotic stress GO:0006970 27 16 1,000 3,416E-03 0,04908891 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,416E-03 0,04880184 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 3,416E-03 0,04851811 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! cell maturation GO:0048469 107 55 2,000 3,459E-03 0,04884246 ! skeletal muscle fiber development GO:0048741 130 56 2,000 3,64E-03 0,05110541 ! muscle fiber development GO:0048747 131 57 2,000 3,827E-03 0,05342197 ! gene silencing by RNA GO:0031047 38 17 1,000 3,857E-03 0,05354413 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 3,857E-03 0,05324162 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,857E-03 0,05294251 ! cardiac muscle tissue development GO:0048738 34 17 1,000 3,857E-03 0,05264674 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 3,857E-03 0,05235426 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 3,857E-03 0,05206501 ! maintenance of location GO:0051235 124 58 2,000 4,019E-03 0,05395269 ! positive regulation of protein complex assembly GO:0031334 34 18 1,000 4,324E-03 0,05772464 ! centrosome cycle GO:0007098 26 18 1,000 4,324E-03 0,05741092 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 4,324E-03 0,05710059 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 4,324E-03 0,0567936 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 4,324E-03 0,05648989 ! nerve development GO:0021675 34 18 1,000 4,324E-03 0,05618941 ! regulation of neurotransmitter levels GO:0001505 113 60 2,000 4,422E-03 0,05715931 ! neuron maturation GO:0042551 46 19 1,000 4,815E-03 0,06191549 ! memory GO:0007613 34 19 1,000 4,815E-03 0,06159133 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 4,815E-03 0,06127054 ! response to lipopolysaccharide GO:0032496 34 19 1,000 4,815E-03 0,06095308 ! peptide cross-linking GO:0018149 39 19 1,000 4,815E-03 0,06063889 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 4,815E-03 0,06032792 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 1,000 4,815E-03 0,06002012 ! regulation of homeostatic process GO:0032844 148 62 2,000 4,848E-03 0,06012427 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 5,299E-03 0,06537593 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 5,331E-03 0,06544764 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,331E-03 0,0651204 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,331E-03 0,06479642 ! response to alkaloid GO:0043279 38 20 1,000 5,331E-03 0,06447565 ! pancreas development GO:0031016 40 20 1,000 5,331E-03 0,06415803 ! regulation of interleukin-2 production GO:0032663 39 20 1,000 5,331E-03 0,06384353 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 5,331E-03 0,0635321 ! aromatic compound catabolic process GO:0019439 31 20 1,000 5,331E-03 0,06322369 ! negative regulation of T cell activation GO:0050868 41 20 1,000 5,331E-03 0,06291826 ! negative regulation of coagulation GO:0050819 30 20 1,000 5,331E-03 0,06261577 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 5,773E-03 0,06748252 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 5,773E-03 0,06716118 ! lipid phosphorylation GO:0046834 43 21 1,000 5,871E-03 0,06797788 ! smooth muscle contraction GO:0006939 48 21 1,000 5,871E-03 0,06765723 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 5,871E-03 0,06733959 ! actin filament-based movement GO:0030048 47 21 1,000 5,871E-03 0,06702492 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 2,000 6,02E-03 0,06840052 ! negative regulation of ligase activity GO:0051352 116 68 2,000 6,272E-03 0,07094236 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 2,000 6,272E-03 0,07061543 ! positive regulation of T cell activation GO:0050870 124 68 2,000 6,272E-03 0,07029151 ! inactivation of MAPK activity GO:0000188 45 22 1,000 6,435E-03 0,07178549 ! cellular response to starvation GO:0009267 37 22 1,000 6,435E-03 0,0714592 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 6,435E-03 0,07113585 ! positive regulation of adaptive immune response GO:0002821 42 22 1,000 6,435E-03 0,07081542 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,435E-03 0,07049786 ! regulation of cytokine secretion GO:0050707 41 22 1,000 6,435E-03 0,07018314 ! positive regulation of B cell activation GO:0050871 42 22 1,000 6,435E-03 0,06987121 ! protein stabilization GO:0050821 41 22 1,000 6,435E-03 0,06956205 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 2,000 6,531E-03 0,07029186 ! developmental maturation GO:0021700 128 69 2,000 6,531E-03 0,06998356 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 7,023E-03 0,07491911 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 7,023E-03 0,07459337 ! visual behavior GO:0007632 46 23 1,000 7,023E-03 0,07427046 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 7,023E-03 0,07395033 GO:0010810|regulation of cell-substrate adhesion, ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 7,023E-03 0,07363294 ! DNA modification GO:0006304 36 23 1,000 7,023E-03 0,07331827 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 7,023E-03 0,07300628 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 7,068E-03 0,07316877 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 7,634E-03 0,07868786 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,634E-03 0,07835723 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 7,634E-03 0,07802938 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 7,634E-03 0,07770426 ! sex determination GO:0007530 48 24 1,000 7,634E-03 0,07738183 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 1,000 7,634E-03 0,07706207 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 1,000 7,634E-03 0,07674495 ! oogenesis GO:0048477 44 24 1,000 7,634E-03 0,07643042 ! detection of biotic stimulus GO:0009595 34 24 1,000 7,634E-03 0,07611846 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 7,634E-03 0,07580903 ! negative regulation of catabolic process GO:0009895 52 24 1,000 7,634E-03 0,07550211 ! acute inflammatory response GO:0002526 118 74 2,000 7,921E-03 0,07803196 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 8,268E-03 0,08111646 ! receptor metabolic process GO:0043112 53 25 1,000 8,268E-03 0,080792 ! interaction with host GO:0051701 66 25 1,000 8,268E-03 0,08047012 ! leukocyte homeostasis GO:0001776 50 25 1,000 8,268E-03 0,08015079 ! neurotransmitter transport GO:0006836 142 77 2,000 8,833E-03 0,08528865 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 8,925E-03 0,0858376 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 8,925E-03 0,08550098 ! microtubule organizing center organization GO:0031023 42 26 1,000 8,925E-03 0,08516699 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 8,925E-03 0,0848356 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 8,925E-03 0,08450678 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 8,925E-03 0,0841805 ! protein oligomerization GO:0051259 149 79 2,000 9,473E-03 0,08900759 ! regulation of synaptic transmission GO:0050804 159 79 2,000 9,473E-03 0,08866656 ! regulation of interferon-gamma production GO:0032649 43 27 1,000 9,604E-03 0,08955199 ! response to starvation GO:0042594 47 27 1,000 9,604E-03 0,08921149 ! cellular response to oxidative stress GO:0034599 43 27 1,000 9,604E-03 0,08887356 ! regulation of chromosome organization GO:0033044 49 27 1,000 9,604E-03 0,08853819 ! cellular response to nutrient levels GO:0031669 45 27 1,000 9,604E-03 0,08820534 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 9,604E-03 0,08787498 ! positive regulation of phosphorylation GO:0042327 149 81 2,000 0,01013935 0,09242702 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 0,01013935 0,09208342 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01030576 0,09324803 ! protein import into nucleus GO:0006606 174 82 2,000 0,01048261 0,09449825 ! exocytosis GO:0006887 153 83 2,000 0,01083255 0,09729382 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 2,000 0,01083255 0,09693744 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 2,000 0,01083255 0,09658365 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,01102953 0,09798235 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 0,01102953 0,09762734 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 0,01102953 0,0972749 ! cholesterol metabolic process GO:0008203 148 85 2,000 0,01155254 0,10152108 ! regulation of transmission of nerve impulse GO:0051969 167 85 2,000 0,01155254 0,1011572 ! acute-phase response GO:0006953 50 30 1,000 0,01177508 0,10273758 ! complement activation, classical pathway GO:0006958 51 30 1,000 0,01177508 0,10237197 ! myofibril assembly GO:0030239 50 30 1,000 0,01177508 0,10200895 GO:0055002|striated muscle cell development, ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01177508 0,10164849 ! regulation of coagulation GO:0050818 52 30 1,000 0,01177508 0,10129057 ! mitochondrion organization GO:0007005 159 87 2,000 0,01229949 0,10543041 ! regulation of protein transport GO:0051223 165 87 2,000 0,01229949 0,10506177 GO:0070201|regulation of establishment of protein localization, ! iron ion homeostasis GO:0055072 60 31 1,000 0,01254215 0,10676121 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 0,01254215 0,10639051 ! positive regulation of immune effector process GO:0002699 78 31 1,000 0,01254215 0,10602237 ! protein localization in nucleus GO:0034504 192 89 2,000 0,01307356 0,11013348 ! regulation of neurological system process GO:0031644 175 89 2,000 0,01307356 0,10975502 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 0,01333047 0,1115286 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01333047 0,11114795 ! positive regulation of T cell proliferation GO:0042102 60 32 1,000 0,01333047 0,1107699 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 0,01333047 0,11039441 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01333047 0,11002145 ! muscle cell development GO:0055001 52 32 1,000 0,01333047 0,10965101 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01333047 0,10928305 ! gene silencing GO:0016458 71 32 1,000 0,01333047 0,10891756 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01428579 0,11633396 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01470356 0,11933821 ! glial cell differentiation GO:0010001 67 34 1,000 0,0149699 0,12109757 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,0149699 0,12069791 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,0149699 0,12030088 ! sterol metabolic process GO:0016125 166 94 2,000 0,0151282 0,12117442 ! regulation of membrane potential GO:0042391 179 94 2,000 0,0151282 0,12077843 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,01644346 0,13085135 ! regulation of protein localization GO:0032880 188 97 2,000 0,01644346 0,13042651 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,01669135 0,13196431 ! cytokine production GO:0001816 68 36 1,000 0,01669135 0,13153862 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01758222 0,1381137 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01758222 0,13767103 ! actomyosin structure organization GO:0031032 68 37 1,000 0,01758222 0,13723119 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01758222 0,13679414 ! negative regulation of cell activation GO:0050866 69 37 1,000 0,01758222 0,13635988 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01782092 0,13777372 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 2,000 0,01782092 0,13733911 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,01849286 0,14206933 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,01849286 0,14162397 ! regulation of protein stability GO:0031647 77 38 1,000 0,01849286 0,1411814 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 1,000 0,01942302 0,14782069 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,02037248 0,15456508 GO:0006956|complement activation, ! cellular amide metabolic process GO:0043603 73 41 1,000 0,02134098 0,16141181 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,02134098 0,16091363 ! maintenance of protein location GO:0045185 95 41 1,000 0,02134098 0,16041851 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,0223283 0,16732528 ! ear morphogenesis GO:0042471 64 42 1,000 0,0223283 0,16681358 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,0223283 0,16630501 ! regulation of leukocyte mediated immunity GO:0002703 84 42 1,000 0,0223283 0,16579952 ! regulation of protein secretion GO:0050708 77 42 1,000 0,0223283 0,1652971 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02333421 0,17222195 GO:0090047|positive regulation of transcription regulator activity, ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02333421 0,17170321 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,02333421 0,17118758 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,02435846 0,17816683 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 0,02435846 0,17763499 ! striated muscle contraction GO:0006941 85 44 1,000 0,02435846 0,17710631 ! biopolymer methylation GO:0043414 91 45 1,000 0,02540084 0,18413724 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 1,000 0,02540084 0,18359245 ! female gamete generation GO:0007292 71 45 1,000 0,02540084 0,18305088 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,02646111 0,19013086 ! glycolysis GO:0006096 71 46 1,000 0,02646111 0,18957329 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,02646111 0,18901899 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 0,02646111 0,18846791 ! pigmentation GO:0043473 103 46 1,000 0,02646111 0,18792004 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,02646111 0,18737534 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02713297 0,19157757 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02713297 0,19102547 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02713297 0,19047655 GO:0045844|positive regulation of striated muscle development, ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02713297 0,18993077 ! neuron fate determination GO:0048664 7 5 0,000 0,02713297 0,18938811 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02713297 0,18884855 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02713297 0,18831204 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02713297 0,18777858 ! polyol transport GO:0015791 12 5 0,000 0,02713297 0,18724813 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02713297 0,18672067 ! response to superoxide GO:0000303 10 5 0,000 0,02713297 0,18619618 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02713297 0,18567462 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02713297 0,18515598 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02713297 0,18464022 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02713297 0,18412733 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02713297 0,18361728 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02713297 0,18311005 ! hypothalamus development GO:0021854 9 5 0,000 0,02713297 0,18260562 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02713297 0,18210395 ! cobalt ion transport GO:0006824 11 5 0,000 0,02713297 0,18160504 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02713297 0,18110885 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02713297 0,18061537 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02713297 0,18012456 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02713297 0,17963642 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02713297 0,17915092 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02713297 0,17866803 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02713297 0,17818774 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02713297 0,17771003 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02713297 0,17723486 ! transposition GO:0032196 9 5 0,000 0,02713297 0,17676224 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02713297 0,17629213 ! negative chemotaxis GO:0050919 16 5 0,000 0,02713297 0,17582451 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02713297 0,17535936 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02713297 0,17489667 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02713297 0,17443642 ! behavioral response to pain GO:0048266 10 5 0,000 0,02713297 0,17397858 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02713297 0,17352314 ! Notch receptor processing GO:0007220 11 5 0,000 0,02713297 0,17307008 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02713297 0,17261937 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02713297 0,17217101 ! micturition GO:0060073 9 5 0,000 0,02713297 0,17172497 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02713297 0,17128124 ! copulation GO:0007620 9 5 0,000 0,02713297 0,17083979 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02713297 0,17040062 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02713297 0,16996369 ! bioluminescence GO:0008218 9 5 0,000 0,02713297 0,169529 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02713297 0,16909653 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02713297 0,16866626 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02713297 0,16823817 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02713297 0,16781225 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02713297 0,16738848 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02713297 0,16696685 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02713297 0,16654734 ! grooming behavior GO:0007625 6 5 0,000 0,02713297 0,16612992 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02713297 0,1657146 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02713297 0,16530135 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02713297 0,16489015 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02713297 0,16448099 ! response to protozoan GO:0001562 13 5 0,000 0,02713297 0,16407386 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02713297 0,16366874 ! lymph vessel development GO:0001945 10 5 0,000 0,02713297 0,16326561 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02713297 0,16286447 ! endochondral ossification GO:0001958 17 5 0,000 0,02713297 0,16246529 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02713297 0,16206807 ! single strand break repair GO:0000012 8 5 0,000 0,02713297 0,16167278 ! parathyroid gland development GO:0060017 14 5 0,000 0,02713297 0,16127941 ! anagen GO:0042640 7 5 0,000 0,02713297 0,16088796 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02713297 0,1604984 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02713297 0,16011072 ! cytokine secretion GO:0050663 15 5 0,000 0,02713297 0,15972491 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02713297 0,15934096 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02713297 0,15895885 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02713297 0,15857856 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02713297 0,15820009 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02713297 0,15782343 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02713297 0,15744855 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02713297 0,15707545 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02713297 0,15670411 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02713297 0,15633453 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02713297 0,15596668 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02713297 0,15560056 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02713297 0,15523616 ! microvillus organization GO:0032528 8 5 0,000 0,02713297 0,15487346 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02713297 0,15451245 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02713297 0,15415311 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02713297 0,15379545 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02713297 0,15343944 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02713297 0,15308508 ! polyol catabolic process GO:0046174 9 5 0,000 0,02713297 0,15273235 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02713297 0,15238124 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02713297 0,15203174 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02713297 0,15168384 ! muscle cell migration GO:0014812 8 5 0,000 0,02713297 0,15133753 ! mitochondrial fission GO:0000266 8 5 0,000 0,02713297 0,1509928 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02713297 0,15064964 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02713297 0,15030803 ! mRNA transcription GO:0009299 10 5 0,000 0,02713297 0,14996796 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02713297 0,14962943 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02713297 0,14929243 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02713297 0,14895694 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02713297 0,14862296 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02713297 0,14829047 ! monocyte activation GO:0042117 10 5 0,000 0,02713297 0,14795946 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02713297 0,14762993 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02713297 0,14730187 ! response to food GO:0032094 6 5 0,000 0,02713297 0,14697525 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02713297 0,14665009 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02713297 0,14632636 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02713297 0,14600405 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02713297 0,14568316 ! forebrain neuron development GO:0021884 13 5 0,000 0,02713297 0,14536368 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02713297 0,1450456 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02713297 0,14472891 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02713297 0,14441359 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02713297 0,14409965 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02713297 0,14378707 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02713297 0,14347584 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02713297 0,14316596 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02713297 0,14285741 ! lipid glycosylation GO:0030259 7 5 0,000 0,02713297 0,14255019 ! nucleobase transport GO:0015851 6 5 0,000 0,02713297 0,14224429 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02713297 0,1419397 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02713297 0,14163641 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02713297 0,14133441 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02713297 0,1410337 ! basic amino acid transport GO:0015802 12 5 0,000 0,02713297 0,14073427 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02713297 0,1404361 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02713297 0,1401392 ! actin nucleation GO:0045010 11 5 0,000 0,02713297 0,13984354 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02713297 0,13954914 ! depurination GO:0045007 5 5 0,000 0,02713297 0,13925597 ! depyrimidination GO:0045008 10 5 0,000 0,02713297 0,13896402 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02713297 0,1386733 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02713297 0,1383838 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02713297 0,1380955 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02713297 0,1378084 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02713297 0,13752249 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02713297 0,13723776 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02713297 0,13695421 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02713297 0,13667183 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02713297 0,13639062 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02713297 0,13611055 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02713297 0,13583164 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02713297 0,13555386 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02713297 0,13527722 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02713297 0,13500171 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02713297 0,13472732 ! response to arsenic GO:0046685 11 5 0,000 0,02713297 0,13445404 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02713297 0,13418186 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02713297 0,13391079 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02713297 0,13364081 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02713297 0,13337191 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02713297 0,1331041 ! response to mercury ion GO:0046689 8 5 0,000 0,02713297 0,13283735 ! response to cadmium ion GO:0046686 7 5 0,000 0,02713297 0,13257168 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02713297 0,13230706 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02713297 0,1320435 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02713297 0,13178099 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02713297 0,13151952 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02713297 0,13125909 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02713297 0,13099968 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02713297 0,1307413 ! decidualization GO:0046697 11 5 0,000 0,02713297 0,13048394 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02713297 0,13022758 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02713297 0,12997223 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02713297 0,12971789 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02713297 0,12946453 ! embryonic cleavage GO:0040016 6 5 0,000 0,02713297 0,12921216 ! peroxisome fission GO:0016559 5 5 0,000 0,02713297 0,12896078 ! histone demethylation GO:0016577 13 5 0,000 0,02713297 0,12871037 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02713297 0,12846093 ! mitotic recombination GO:0006312 9 5 0,000 0,02713297 0,12821246 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02713297 0,12796494 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02713297 0,12771838 ! metaphase plate congression GO:0051310 7 5 0,000 0,02713297 0,12747277 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02713297 0,1272281 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02713297 0,12698437 ! enteric nervous system development GO:0048484 8 5 0,000 0,02713297 0,12674157 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02713297 0,12649969 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02713297 0,12625874 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02713297 0,12601871 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02713297 0,12577958 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02713297 0,12554136 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02713297 0,12530404 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02713297 0,12506762 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02713297 0,12483209 ! metaphase GO:0051323 11 5 0,000 0,02713297 0,12459744 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02713297 0,12436368 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02713297 0,12413079 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02713297 0,12389877 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02713297 0,12366761 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02713297 0,12343732 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02713297 0,12320788 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02713297 0,12297929 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02713297 0,12275155 ! response to redox state GO:0051775 6 5 0,000 0,02713297 0,12252466 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02713297 0,1222986 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02713297 0,12207337 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02713297 0,12184897 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02713297 0,12162539 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02713297 0,12140264 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02713297 0,12118069 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02713297 0,12095956 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02713297 0,12073923 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02713297 0,12051971 ! striatum development GO:0021756 14 5 0,000 0,02713297 0,12030098 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02713297 0,12008304 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02713297 0,11986589 ! glial cell migration GO:0008347 10 5 0,000 0,02713297 0,11964953 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02713297 0,11943394 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02713297 0,11921914 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02713297 0,1190051 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02713297 0,11879183 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02713297 0,11857932 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02713297 0,11836757 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02713297 0,11815658 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02713297 0,11794633 ! neuroprotection GO:0043526 8 5 0,000 0,02713297 0,11773684 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02713297 0,11752808 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02713297 0,11732007 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02713297 0,11711279 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02713297 0,11690624 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02713297 0,11670042 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02713297 0,11649532 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02713297 0,11629095 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02713297 0,11608728 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02713297 0,11588433 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02713297 0,11568209 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02713297 0,11548056 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02713297 0,11527972 ! spindle assembly GO:0051225 6 5 0,000 0,02713297 0,11507958 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02713297 0,11488014 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02713297 0,11468138 ! protein palmitoylation GO:0018345 12 5 0,000 0,02713297 0,11448332 ! drug metabolic process GO:0017144 7 5 0,000 0,02713297 0,11428593 ! stem cell division GO:0017145 11 5 0,000 0,02713297 0,11408922 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02713297 0,11389319 ! organ regeneration GO:0031100 7 5 0,000 0,02713297 0,11369784 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02713297 0,11350315 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02713297 0,11330913 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,02753905 0,11480871 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,02863444 0,11917194 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02863444 0,11896927 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,02863444 0,11876728 ! endosome transport GO:0016197 127 48 1,000 0,02863444 0,11856598 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02863444 0,11836536 ! regulation of adaptive immune response GO:0002819 92 48 1,000 0,02863444 0,11816542 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,02863444 0,11796615 ! methylation GO:0032259 97 48 1,000 0,02863444 0,11776756 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02974705 0,12213787 ! protein homooligomerization GO:0051260 84 49 1,000 0,02974705 0,12193294 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,03087666 0,12635122 ! endocrine system development GO:0035270 109 50 1,000 0,03087666 0,12613993 ! activation of caspase activity GO:0006919 95 50 1,000 0,03087666 0,12592935 ! regulation of ossification GO:0030278 123 50 1,000 0,03087666 0,12571946 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,03087666 0,12551028 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,03087666 0,12530179 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,03087666 0,12509399 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03202306 0,12952373 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,03202306 0,12930964 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03247102 0,13090215 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03247102 0,1306865 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03247102 0,13047155 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03247102 0,13025731 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03247102 0,13004378 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03247102 0,12983094 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03247102 0,1296188 ! response to oxygen radical GO:0000305 11 6 0,000 0,03247102 0,12940735 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03247102 0,12919659 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03247102 0,12898651 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03247102 0,12877712 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03247102 0,1285684 ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03247102 0,12836036 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03247102 0,12815299 ! forebrain regionalization GO:0021871 9 6 0,000 0,03247102 0,1279463 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03247102 0,12774026 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03247102 0,12753489 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03247102 0,12733018 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03247102 0,12712613 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03247102 0,12692273 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03247102 0,12671997 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03247102 0,12651787 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03247102 0,12631641 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03247102 0,12611559 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03247102 0,1259154 ! malate metabolic process GO:0006108 13 6 0,000 0,03247102 0,12571585 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03247102 0,12551694 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03247102 0,12531865 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03247102 0,12512098 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03247102 0,12492394 ! protein refolding GO:0042026 15 6 0,000 0,03247102 0,12472752 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03247102 0,12453172 ! opsonization GO:0008228 8 6 0,000 0,03247102 0,12433653 ! mating behavior GO:0007617 7 6 0,000 0,03247102 0,12414195 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03247102 0,12394797 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03247102 0,12375461 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03247102 0,12356184 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03247102 0,12336968 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03247102 0,12317811 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03247102 0,12298714 ! toxin metabolic process GO:0009404 11 6 0,000 0,03247102 0,12279675 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03247102 0,12260696 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03247102 0,12241775 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03247102 0,12222913 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03247102 0,12204108 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03247102 0,12185361 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03247102 0,12166672 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03247102 0,1214804 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03247102 0,12129465 ! thymic T cell selection GO:0045061 16 6 0,000 0,03247102 0,12110947 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03247102 0,12092485 ! protein lipoylation GO:0009249 10 6 0,000 0,03247102 0,1207408 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03247102 0,1205573 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03247102 0,12037436 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03247102 0,12019197 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03247102 0,12001014 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03247102 0,11982886 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03247102 0,11964812 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03247102 0,11946793 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03247102 0,11928828 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03247102 0,11910916 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03247102 0,11893059 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03247102 0,11875255 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03247102 0,11857504 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03247102 0,11839806 ! urea metabolic process GO:0019627 7 6 0,000 0,03247102 0,11822161 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03247102 0,11804569 ! neutrophil activation GO:0042119 7 6 0,000 0,03247102 0,11787029 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03247102 0,11769541 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03247102 0,11752104 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03247102 0,11734719 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03247102 0,11717386 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03247102 0,11700104 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03247102 0,11682872 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03247102 0,11665692 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03247102 0,11648561 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03247102 0,11631481 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03247102 0,11614451 ! carnitine transport GO:0015879 10 6 0,000 0,03247102 0,11597471 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03247102 0,11580541 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03247102 0,11563659 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03247102 0,11546827 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03247102 0,11530044 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03247102 0,1151331 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03247102 0,11496624 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03247102 0,11479986 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03247102 0,11463396 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03247102 0,11446855 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03247102 0,11430361 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03247102 0,11413914 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03247102 0,11397515 ! response to UV-C GO:0010225 14 6 0,000 0,03247102 0,11381163 ! astrocyte development GO:0014002 16 6 0,000 0,03247102 0,11364857 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03247102 0,11348598 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03247102 0,11332386 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03247102 0,1131622 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03247102 0,113001 ! response to copper ion GO:0046688 10 6 0,000 0,03247102 0,11284026 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03247102 0,11267998 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03247102 0,11252015 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03247102 0,11236077 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03247102 0,11220184 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03247102 0,11204337 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03247102 0,11188534 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03247102 0,11172775 ! hair follicle maturation GO:0048820 8 6 0,000 0,03247102 0,11157061 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03247102 0,11141391 ! Schwann cell development GO:0014044 15 6 0,000 0,03247102 0,11125765 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03247102 0,11110183 ! response to pheromone GO:0019236 6 6 0,000 0,03247102 0,11094644 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03247102 0,11079149 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03247102 0,11063696 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03247102 0,11048287 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03247102 0,11032921 ! subpallium development GO:0021544 15 6 0,000 0,03247102 0,11017598 ! neural tube patterning GO:0021532 8 6 0,000 0,03247102 0,11002317 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03247102 0,10987078 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03247102 0,10971882 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03247102 0,10956727 ! G2 phase GO:0051319 16 6 0,000 0,03247102 0,10941614 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03247102 0,10926543 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03247102 0,10911514 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03247102 0,10896525 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03247102 0,10881578 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03247102 0,10866672 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03247102 0,10851806 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03247102 0,10836981 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03247102 0,10822197 ! receptor internalization GO:0031623 11 6 0,000 0,03247102 0,10807453 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03247102 0,10792749 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03247102 0,10778085 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03247102 0,1076346 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03247102 0,10748876 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03247102 0,10734331 ! protein deubiquitination GO:0016579 16 6 0,000 0,03247102 0,10719825 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03247102 0,10705358 ! protein destabilization GO:0031648 9 6 0,000 0,03247102 0,1069093 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03247102 0,10676541 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03247102 0,10662191 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03247102 0,1064788 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03247102 0,10633606 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03247102 0,10619371 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03247102 0,10605174 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03247102 0,10591015 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03247102 0,10576894 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03247102 0,1056281 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03247102 0,10548764 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03247102 0,10534755 ! neural plate development GO:0001840 9 6 0,000 0,03247102 0,10520783 ! catecholamine transport GO:0051937 9 6 0,000 0,03247102 0,10506848 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03247102 0,1049295 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03247102 0,10479089 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03247102 0,10465264 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03247102 0,10451476 ! maternal placenta development GO:0001893 12 6 0,000 0,03247102 0,10437724 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03247102 0,10424008 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03247102 0,10410329 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03247102 0,10396685 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03247102 0,10383076 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03247102 0,10369504 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03247102 0,10355966 GO:0055081|anion homeostasis, ! positive regulation of binding GO:0051099 88 52 1,000 0,03318603 0,10570204 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,03318603 0,1055644 ! excretion GO:0007588 87 52 1,000 0,03318603 0,10542713 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,03318603 0,10529021 ! positive regulation of growth GO:0045927 96 53 1,000 0,03436535 0,10889047 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,03436535 0,10874942 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,03436535 0,10860873 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03556082 0,1122417 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03677221 0,11591551 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,03677221 0,11576613 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03677221 0,11561714 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,03677221 0,11546853 ! tRNA transcription GO:0009304 17 7 0,000 0,03777993 0,11848059 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03777993 0,11832869 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03777993 0,11817718 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03777993 0,11802606 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03777993 0,11787532 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03777993 0,11772497 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03777993 0,117575 ! sleep GO:0030431 16 7 0,000 0,03777993 0,11742542 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03777993 0,11727621 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03777993 0,11712738 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03777993 0,11697893 ! prostate gland development GO:0030850 14 7 0,000 0,03777993 0,11683086 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03777993 0,11668316 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03777993 0,11653583 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03777993 0,11638887 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03777993 0,11624229 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03777993 0,11609607 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03777993 0,11595022 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03777993 0,11580474 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03777993 0,11565962 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03777993 0,11551487 ! glycolipid transport GO:0046836 11 7 0,000 0,03777993 0,11537047 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03777993 0,11522644 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03777993 0,11508277 ! neuron adhesion GO:0007158 14 7 0,000 0,03777993 0,11493945 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03777993 0,11479649 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03777993 0,11465389 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03777993 0,11451163 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03777993 0,11436974 ! mRNA stabilization GO:0048255 18 7 0,000 0,03777993 0,11422819 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03777993 0,11408699 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03777993 0,11394615 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03777993 0,11380564 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03777993 0,11366549 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03777993 0,11352568 ! lipoprotein transport GO:0042953 14 7 0,000 0,03777993 0,11338621 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03777993 0,11324709 ! rhythmic behavior GO:0007622 17 7 0,000 0,03777993 0,11310831 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03777993 0,11296986 GO:0042069|regulation of catecholamine metabolic process, ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03777993 0,11283176 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03777993 0,11269399 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03777993 0,11255656 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03777993 0,11241946 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03777993 0,1122827 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03777993 0,11214627 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03777993 0,11201017 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03777993 0,1118744 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03777993 0,11173896 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03777993 0,11160384 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03777993 0,11146906 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03777993 0,11133459 ! spinal cord patterning GO:0021511 14 7 0,000 0,03777993 0,11120046 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03777993 0,11106664 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03777993 0,11093315 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03777993 0,11079997 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03777993 0,11066712 ! adrenal gland development GO:0030325 17 7 0,000 0,03777993 0,11053458 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03777993 0,11040237 ! ovulation GO:0030728 10 7 0,000 0,03777993 0,11027046 ! adenohypophysis development GO:0021984 11 7 0,000 0,03777993 0,11013888 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03777993 0,1100076 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03777993 0,10987664 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03777993 0,10974599 ! microtubule nucleation GO:0007020 21 7 0,000 0,03777993 0,10961565 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03777993 0,10948562 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03777993 0,1093559 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03777993 0,10922648 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03777993 0,10909737 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03777993 0,10896857 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03777993 0,10884007 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03777993 0,10871187 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03777993 0,10858397 ! galactose metabolic process GO:0006012 13 7 0,000 0,03777993 0,10845638 ! vesicle fusion GO:0006906 20 7 0,000 0,03777993 0,10832908 ! response to dietary excess GO:0002021 8 7 0,000 0,03777993 0,10820208 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03777993 0,10807538 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03777993 0,10794898 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03777993 0,10782287 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03777993 0,10769706 ! organ growth GO:0035265 15 7 0,000 0,03777993 0,10757154 ! nucleoside transport GO:0015858 11 7 0,000 0,03777993 0,10744631 ! nucleoside salvage GO:0043174 11 7 0,000 0,03777993 0,10732137 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03777993 0,10719672 ! male sex determination GO:0030238 15 7 0,000 0,03777993 0,10707236 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03777993 0,10694829 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03777993 0,10682451 ! parturition GO:0007567 16 7 0,000 0,03777993 0,10670101 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03777993 0,1065778 ! rRNA modification GO:0000154 14 7 0,000 0,03777993 0,10645488 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03777993 0,10633223 ! spindle checkpoint GO:0031577 16 7 0,000 0,03777993 0,10620987 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03777993 0,10608779 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03777993 0,10596599 ! monocyte differentiation GO:0030224 16 7 0,000 0,03777993 0,10584447 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03777993 0,10572323 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03777993 0,10560226 GO:0046676|negative regulation of insulin secretion, ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03777993 0,10548157 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03777993 0,10536116 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03777993 0,10524102 ! fibrinolysis GO:0042730 11 7 0,000 0,03777993 0,10512116 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03777993 0,10500157 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03777993 0,10488225 ! eating behavior GO:0042755 8 7 0,000 0,03777993 0,1047632 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03777993 0,10464442 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03777993 0,10452591 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03777993 0,10440767 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03777993 0,10428969 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03777993 0,10417198 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03777993 0,10405454 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03777993 0,10393736 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03777993 0,10382045 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03777993 0,1037038 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03777993 0,1035874 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03777993 0,10347128 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03777993 0,10335541 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03777993 0,1032398 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03777993 0,10312444 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03777993 0,10300935 ! histone ubiquitination GO:0016574 9 7 0,000 0,03777993 0,10289451 ! regulation of meiosis GO:0040020 12 7 0,000 0,03777993 0,10277993 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03777993 0,1026656 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03777993 0,10255153 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03777993 0,10243771 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03777993 0,10232414 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03777993 0,10221083 ! transcription termination GO:0006353 14 7 0,000 0,03777993 0,10209776 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03777993 0,10198495 ! anaphase GO:0051322 18 7 0,000 0,03777993 0,10187238 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03777993 0,10176006 ! axonal fasciculation GO:0007413 19 7 0,000 0,03777993 0,10164799 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03777993 0,10153617 GO:0045839|negative regulation of mitosis, ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03777993 0,10142459 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03777993 0,10131326 ! diuresis GO:0030146 12 7 0,000 0,03777993 0,10120217 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03777993 0,10109132 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03777993 0,10098072 ! antibiotic transport GO:0042891 9 7 0,000 0,03777993 0,10087036 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03777993 0,10076024 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03777993 0,10065036 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03777993 0,10054072 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03777993 0,10043131 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03777993 0,10032215 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03777993 0,10021322 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03777993 0,10010453 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03777993 0,09999608 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03777993 0,09988785 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03777993 0,09977987 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03777993 0,09967211 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03777993 0,09956459 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03777993 0,0994573 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03777993 0,09935025 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03777993 0,09924342 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03777993 0,09913682 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03777993 0,09903045 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03777993 0,09892431 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03777993 0,09881839 ! muscle adaptation GO:0043500 13 7 0,000 0,03777993 0,0987127 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03777993 0,09860724 ! retina homeostasis GO:0001895 12 7 0,000 0,03777993 0,098502 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03777993 0,09839699 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03777993 0,0982922 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03777993 0,09818764 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03777993 0,09808329 ! glucose catabolic process GO:0006007 88 56 1,000 0,03799934 0,09854817 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03799934 0,09844367 ! regulation of DNA replication GO:0006275 105 56 1,000 0,03799934 0,09833938 ! RNA elongation GO:0006354 90 56 1,000 0,03799934 0,09823532 ! chloride transport GO:0006821 102 57 1,000 0,03924197 0,10134053 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,03924197 0,10123352 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,03924197 0,10112673 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03924197 0,10102017 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03924197 0,10091383 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,03924197 0,10080772 ! regulation of actin filament length GO:0030832 118 58 1,000 0,04049992 0,10392995 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,04049992 0,10382089 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,04049992 0,10371207 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,04049992 0,10360347 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04049992 0,1034951 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04305986 0,10992189 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04305986 0,10980715 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04305986 0,10969265 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04305986 0,10957838 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04305986 0,10946436 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04305986 0,10935057 ! male meiosis GO:0007140 9 8 0,000 0,04305986 0,10923702 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04305986 0,1091237 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04305986 0,10901062 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04305986 0,10889777 ! meiotic prophase I GO:0007128 14 8 0,000 0,04305986 0,10878516 ! response to zinc ion GO:0010043 12 8 0,000 0,04305986 0,10867278 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04305986 0,10856063 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04305986 0,10844871 ! oligopeptide transport GO:0006857 16 8 0,000 0,04305986 0,10833702 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04305986 0,10822557 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04305986 0,10811434 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04305986 0,10800334 ! signal peptide processing GO:0006465 12 8 0,000 0,04305986 0,10789256 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04305986 0,10778202 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04305986 0,1076717 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04305986 0,1075616 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04305986 0,10745174 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04305986 0,10734209 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04305986 0,10723267 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04305986 0,10712347 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04305986 0,1070145 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04305986 0,10690574 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04305986 0,10679721 ! reflex GO:0060004 17 8 0,000 0,04305986 0,10668889 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04305986 0,1065808 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04305986 0,10647292 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04305986 0,10636527 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04305986 0,10625783 ! pigment granule organization GO:0048753 17 8 0,000 0,04305986 0,10615061 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04305986 0,1060436 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04305986 0,10593681 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04305986 0,10583023 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04305986 0,10572387 ! histidine catabolic process GO:0006548 10 8 0,000 0,04305986 0,10561772 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04305986 0,10551178 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04305986 0,10540606 ! ER overload response GO:0006983 13 8 0,000 0,04305986 0,10530055 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04305986 0,10519525 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04305986 0,10509016 ! melanin metabolic process GO:0006582 17 8 0,000 0,04305986 0,10498528 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04305986 0,10488061 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04305986 0,10477615 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04305986 0,10467189 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04305986 0,10456784 ! macrophage activation GO:0042116 13 8 0,000 0,04305986 0,104464 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04305986 0,10436037 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04305986 0,10425694 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04305986 0,10415371 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04305986 0,10405069 ! purine salvage GO:0043101 12 8 0,000 0,04305986 0,10394788 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04305986 0,10384526 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04305986 0,10374285 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04305986 0,10364064 ! osteoblast development GO:0002076 17 8 0,000 0,04305986 0,10353863 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04305986 0,10343682 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04305986 0,10333522 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04305986 0,10323381 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04305986 0,1031326 ! response to UV-B GO:0010224 17 8 0,000 0,04305986 0,10303159 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04305986 0,10293077 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04305986 0,10283016 ! intermediate filament organization GO:0045109 12 8 0,000 0,04305986 0,10272974 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04305986 0,10262951 ! cellular extravasation GO:0045123 13 8 0,000 0,04305986 0,10252948 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04305986 0,10242965 ! response to antibiotic GO:0046677 11 8 0,000 0,04305986 0,10233001 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04305986 0,10223056 ! DNA topological change GO:0006265 12 8 0,000 0,04305986 0,10213131 ! response to tropane GO:0014073 15 8 0,000 0,04305986 0,10203225 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,04305986 0,10193338 ! melanosome transport GO:0032402 13 8 0,000 0,04305986 0,1018347 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04305986 0,10173622 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04305986 0,10163792 ! mast cell activation GO:0045576 14 8 0,000 0,04305986 0,10153982 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04305986 0,1014419 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04305986 0,10134417 ! gas homeostasis GO:0033483 14 8 0,000 0,04305986 0,10124663 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04305986 0,10114928 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04305986 0,10105211 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04305986 0,10095513 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04305986 0,10085834 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04305986 0,10076173 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04305986 0,10066531 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04305986 0,10056907 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04305986 0,10047302 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04305986 0,10037715 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04305986 0,10028146 ! response to tumor cell GO:0002347 16 8 0,000 0,04305986 0,10018595 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04305986 0,10009063 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04305986 0,09999548 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04305986 0,09990052 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04305986 0,09980574 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04305986 0,09971114 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04305986 0,09961671 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04305986 0,09952247 ! hormone catabolic process GO:0042447 17 8 0,000 0,04305986 0,0994284 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04305986 0,09933451 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04305986 0,0992408 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04305986 0,09914727 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04305986 0,09905391 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04305986 0,09896072 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04305986 0,09886772 ! adult feeding behavior GO:0008343 10 8 0,000 0,04305986 0,09877488 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04305986 0,09868222 ! ATP catabolic process GO:0006200 11 8 0,000 0,04305986 0,09858974 ! blastocyst growth GO:0001832 19 8 0,000 0,04305986 0,09849742 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04305986 0,09840528 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04305986 0,09831332 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04305986 0,09822152 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04305986 0,0981299 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04305986 0,09803844 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04305986 0,09794716 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04305986 0,09785605 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04305986 0,0977651 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04305986 0,09767433 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04305986 0,09758372 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04305986 0,09749328 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04305986 0,09740301 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04305986 0,0973129 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04305986 0,09722297 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04305986 0,09713319 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04305986 0,09704359 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04305986 0,09695415 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04305986 0,09686487 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04305986 0,09677576 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04305986 0,09668681 ! lipid modification GO:0030258 112 60 1,000 0,04306094 0,09660044 ! regulation of cellular component size GO:0032535 125 61 1,000 0,04436361 0,09943147 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,04436361 0,09934033 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,04701227 0,10517489 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,04701227 0,10507867 ! axon extension GO:0048675 16 9 0,000 0,04831097 0,10788273 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04831097 0,1077842 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04831097 0,10768586 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04831097 0,1075877 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04831097 0,10748971 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04831097 0,1073919 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04831097 0,10729428 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04831097 0,10719682 ! reproductive behavior GO:0019098 22 9 0,000 0,04831097 0,10709955 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04831097 0,10700245 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04831097 0,10690553 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04831097 0,10680878 ! UTP metabolic process GO:0046051 10 9 0,000 0,04831097 0,10671221 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04831097 0,10661581 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,04831097 0,10651959 ! artery development GO:0060840 25 9 0,000 0,04831097 0,10642354 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04831097 0,10632766 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04831097 0,10623196 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04831097 0,10613642 ! equilibrioception GO:0050957 20 9 0,000 0,04831097 0,10604106 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04831097 0,10594587 ! chemosensory behavior GO:0007635 21 9 0,000 0,04831097 0,10585085 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04831097 0,10575601 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04831097 0,10566133 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04831097 0,10556682 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04831097 0,10547248 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04831097 0,10537831 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04831097 0,1052843 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04831097 0,10519047 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04831097 0,1050968 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04831097 0,10500329 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04831097 0,10490996 ! protein targeting to ER GO:0045047 25 9 0,000 0,04831097 0,10481679 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04831097 0,10472378 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04831097 0,10463094 ! T cell selection GO:0045058 27 9 0,000 0,04831097 0,10453827 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04831097 0,10444576 ! glycine catabolic process GO:0006546 15 9 0,000 0,04831097 0,10435341 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04831097 0,10426122 ! endosome organization GO:0007032 20 9 0,000 0,04831097 0,1041692 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04831097 0,10407734 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04831097 0,10398564 ! mannose metabolic process GO:0006013 13 9 0,000 0,04831097 0,1038941 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04831097 0,10380273 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04831097 0,10371151 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04831097 0,10362046 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04831097 0,10352956 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04831097 0,10343883 ! retinol metabolic process GO:0042572 20 9 0,000 0,04831097 0,10334825 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04831097 0,10325783 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04831097 0,10316757 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04831097 0,10307747 ! macrophage differentiation GO:0030225 15 9 0,000 0,04831097 0,10298752 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04831097 0,10289774 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04831097 0,1028081 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04831097 0,10271863 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04831097 0,10262931 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04831097 0,10254014 ! response to amine stimulus GO:0014075 13 9 0,000 0,04831097 0,10245113 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04831097 0,10236228 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04831097 0,10227357 ! erythrocyte development GO:0048821 17 9 0,000 0,04831097 0,10218502 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04831097 0,10209663 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04831097 0,10200839 ! renal water homeostasis GO:0003091 15 9 0,000 0,04831097 0,1019203 ! postreplication repair GO:0006301 25 9 0,000 0,04831097 0,10183236 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04831097 0,10174457 ! icosanoid secretion GO:0032309 15 9 0,000 0,04831097 0,10165694 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04831097 0,10156945 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04831097 0,10148212 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04831097 0,10139493 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04831097 0,1013079 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04831097 0,10122101 ! sterol catabolic process GO:0016127 14 9 0,000 0,04831097 0,10113428 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04831097 0,10104769 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04831097 0,10096125 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04831097 0,10087496 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04831097 0,10078882 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04831097 0,10070282 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04831097 0,10061697 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04831097 0,10053126 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04831097 0,1004457 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04831097 0,10036029 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04831097 0,10027502 ! purine base metabolic process GO:0006144 25 9 0,000 0,04831097 0,1001899 ! pigment granule transport GO:0051904 17 9 0,000 0,04831097 0,10010492 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04831097 0,10002009 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04831097 0,0999354 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04831097 0,09985085 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04831097 0,09976644 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04831097 0,09968218 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,0497174 0,10249756 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,0497174 0,10241114 ! ear development GO:0043583 114 66 1,000 0,05109066 0,10515121 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,05247746 0,1079145 ! activation of MAPK activity GO:0000187 124 67 1,000 0,05247746 0,10782374 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05353341 0,10990094 ! regulation of developmental growth GO:0048638 16 10 0,000 0,05353341 0,10980867 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05353341 0,10971654 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05353341 0,10962458 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05353341 0,10953276 ! associative learning GO:0008306 21 10 0,000 0,05353341 0,10944111 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05353341 0,1093496 ! phosphate transport GO:0006817 24 10 0,000 0,05353341 0,10925825 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05353341 0,10916705 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05353341 0,109076 ! CTP metabolic process GO:0046036 11 10 0,000 0,05353341 0,1089851 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05353341 0,10889436 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05353341 0,10880376 ! GTP metabolic process GO:0046039 11 10 0,000 0,05353341 0,10871332 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05353341 0,10862302 GO:0007520|myoblast fusion, ! social behavior GO:0035176 29 10 0,000 0,05353341 0,10853288 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05353341 0,10844289 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05353341 0,10835304 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05353341 0,10826335 ! androgen metabolic process GO:0008209 17 10 0,000 0,05353341 0,1081738 ! phospholipid efflux GO:0033700 19 10 0,000 0,05353341 0,1080844 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05353341 0,10799515 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05353341 0,10790604 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05353341 0,10781708 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05353341 0,10772827 ! lung alveolus development GO:0048286 26 10 0,000 0,05353341 0,10763961 ! pathogenesis GO:0009405 17 10 0,000 0,05353341 0,10755109 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05353341 0,10746271 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05353341 0,10737448 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05353341 0,1072864 ! endoderm development GO:0007492 18 10 0,000 0,05353341 0,10719846 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05353341 0,10711066 ! arginine catabolic process GO:0006527 17 10 0,000 0,05353341 0,10702301 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05353341 0,1069355 ! proline metabolic process GO:0006560 13 10 0,000 0,05353341 0,10684814 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05353341 0,10676092 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05353341 0,10667383 ! V(D)J recombination GO:0033151 34 10 0,000 0,05353341 0,1065869 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05353341 0,1065001 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05353341 0,10641344 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05353341 0,10632693 ! B cell proliferation GO:0042100 19 10 0,000 0,05353341 0,10624055 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05353341 0,10615432 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05353341 0,10606822 ! multicellular organism growth GO:0035264 19 10 0,000 0,05353341 0,10598227 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05353341 0,10589645 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05353341 0,10581078 ! ruffle organization GO:0031529 17 10 0,000 0,05353341 0,10572524 ! epithelial cell development GO:0002064 21 10 0,000 0,05353341 0,10563984 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05353341 0,10555458 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05353341 0,10546945 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05353341 0,10538446 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05353341 0,10529961 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05353341 0,1052149 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05353341 0,10513032 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,05353341 0,10504588 ! motor axon guidance GO:0008045 22 10 0,000 0,05353341 0,10496157 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05353341 0,1048774 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05353341 0,10479337 ! protein heterooligomerization GO:0051291 17 10 0,000 0,05353341 0,10470946 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05353341 0,1046257 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05353341 0,10454206 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05353341 0,10445856 ! segment specification GO:0007379 15 10 0,000 0,05353341 0,1043752 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05353341 0,10429196 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05353341 0,10420886 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05353341 0,10412589 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05353341 0,10404306 ! DNA ligation GO:0006266 18 10 0,000 0,05353341 0,10396035 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05353341 0,10387778 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05353341 0,10379533 ! melanosome localization GO:0032400 16 10 0,000 0,05353341 0,10371302 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05353341 0,10363084 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05353341 0,10354879 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05353341 0,10346687 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05353341 0,10338508 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05353341 0,10330341 ! induction of an organ GO:0001759 17 10 0,000 0,05353341 0,10322188 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05353341 0,10314047 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05353341 0,1030592 ! protein sumoylation GO:0016925 17 10 0,000 0,05353341 0,10297805 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05353341 0,10289703 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05353341 0,10281613 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05353341 0,10273537 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05353341 0,10265473 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05353341 0,10257421 ! salivary gland development GO:0007431 28 10 0,000 0,05353341 0,10249383 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05353341 0,10241356 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05353341 0,10233343 ! midbrain development GO:0030901 14 10 0,000 0,05353341 0,10225342 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05353341 0,10217353 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05353341 0,10209377 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05353341 0,10201413 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05353341 0,10193462 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05353341 0,10185523 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05353341 0,10177597 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05353341 0,10169683 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05353341 0,10161781 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05353341 0,10153891 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05353341 0,10146014 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05353341 0,10138149 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05353341 0,10130296 ! blastocyst formation GO:0001825 18 10 0,000 0,05353341 0,10122455 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05353341 0,10114627 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05353341 0,1010681 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05353341 0,10099005 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05353341 0,10091213 ! response to nicotine GO:0035094 20 10 0,000 0,05353341 0,10083433 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05353341 0,10075664 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05353341 0,10067908 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05387761 0,10124846 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,05387761 0,10117064 ! hexose catabolic process GO:0019320 113 68 1,000 0,05387761 0,10109294 ! extracellular matrix organization GO:0030198 146 68 1,000 0,05387761 0,10101535 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05387761 0,10093789 ! adaptive immune response GO:0002250 126 68 1,000 0,05387761 0,10086054 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,05387761 0,10078331 ! negative regulation of cell size GO:0045792 144 69 1,000 0,05529093 0,10334793 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,05529093 0,10326892 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,05529093 0,10319002 ! germ cell development GO:0007281 133 70 1,000 0,05671723 0,10577114 ! activation of immune response GO:0002253 120 70 1,000 0,05671723 0,10569046 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,05671723 0,10560991 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,05815633 0,1082071 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05872734 0,10918636 ! respiratory burst GO:0045730 17 11 0,000 0,05872734 0,10910333 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05872734 0,10902043 ! neuron fate specification GO:0048665 18 11 0,000 0,05872734 0,10893765 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05872734 0,108855 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05872734 0,10877247 ! thyroid gland development GO:0030878 26 11 0,000 0,05872734 0,10869006 ! synapsis GO:0007129 14 11 0,000 0,05872734 0,10860778 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05872734 0,10852563 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05872734 0,1084436 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,05872734 0,10836169 ! response to pain GO:0048265 27 11 0,000 0,05872734 0,10827991 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05872734 0,10819825 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05872734 0,10811672 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,05872734 0,1080353 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05872734 0,10795401 ! bone resorption GO:0045453 16 11 0,000 0,05872734 0,10787284 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,05872734 0,1077918 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05872734 0,10771087 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05872734 0,10763007 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05872734 0,10754939 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05872734 0,10746883 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05872734 0,10738839 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05872734 0,10730807 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05872734 0,10722787 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05872734 0,10714778 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05872734 0,10706782 ! UV protection GO:0009650 20 11 0,000 0,05872734 0,10698798 ! adult heart development GO:0007512 16 11 0,000 0,05872734 0,10690826 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05872734 0,10682865 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05872734 0,10674917 ! macroautophagy GO:0016236 19 11 0,000 0,05872734 0,1066698 ! temperature homeostasis GO:0001659 18 11 0,000 0,05872734 0,10659055 ! behavioral fear response GO:0001662 27 11 0,000 0,05872734 0,10651142 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05872734 0,10643241 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05872734 0,10635351 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05872734 0,10627473 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05872734 0,10619606 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05872734 0,10611752 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05872734 0,10603909 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05872734 0,10596077 ! regulation of organ growth GO:0046620 14 11 0,000 0,05872734 0,10588257 ! pigment granule localization GO:0051875 20 11 0,000 0,05872734 0,10580449 ! vasoconstriction GO:0042310 20 11 0,000 0,05872734 0,10572652 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05872734 0,10564866 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05872734 0,10557092 ! embryonic axis specification GO:0000578 19 11 0,000 0,05872734 0,1054933 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05872734 0,10541579 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05872734 0,10533839 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05872734 0,1052611 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05872734 0,10518393 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05872734 0,10510687 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05872734 0,10502993 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05872734 0,1049531 ! prophase GO:0051324 17 11 0,000 0,05872734 0,10487638 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05872734 0,10479977 ! nucleosome positioning GO:0016584 15 11 0,000 0,05872734 0,10472327 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05872734 0,10464689 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05872734 0,10457061 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05872734 0,10449445 ! apical protein localization GO:0045176 18 11 0,000 0,05872734 0,1044184 ! acid secretion GO:0046717 20 11 0,000 0,05872734 0,10434246 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05872734 0,10426663 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05872734 0,10419091 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05872734 0,1041153 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05872734 0,1040398 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05872734 0,10396441 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05872734 0,10388913 ! cholesterol efflux GO:0033344 21 11 0,000 0,05872734 0,10381395 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05872734 0,10373889 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05872734 0,10366393 ! embryonic gut development GO:0048566 19 11 0,000 0,05872734 0,10358909 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05872734 0,10351435 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05872734 0,10343971 ! activation of innate immune response GO:0002218 16 11 0,000 0,05872734 0,10336519 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05872734 0,10329077 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05872734 0,10321646 ! lysogeny GO:0030069 22 11 0,000 0,05872734 0,10314226 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05872734 0,10306816 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05872734 0,10299417 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05872734 0,10292029 ! regulation of embryonic development GO:0045995 35 11 0,000 0,05872734 0,10284651 ! nucleus localization GO:0051647 22 11 0,000 0,05872734 0,10277284 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,05960805 0,10423941 ! humoral immune response GO:0006959 115 73 1,000 0,0610722 0,10672345 ! regulation of immune effector process GO:0002697 156 73 1,000 0,0610722 0,10664717 ! regulation of caspase activity GO:0043281 136 74 1,000 0,06254861 0,10914733 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,06254861 0,10906942 ! organelle localization GO:0051640 155 74 1,000 0,06254861 0,10899163 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06389291 0,11125472 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06389291 0,11117548 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,06389291 0,11109635 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06389291 0,11101733 ! virus-host interaction GO:0019048 30 12 0,000 0,06389291 0,11093843 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,06389291 0,11085964 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06389291 0,11078096 ! protein complex disassembly GO:0043241 28 12 0,000 0,06389291 0,11070239 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06389291 0,11062393 ! hippocampus development GO:0021766 29 12 0,000 0,06389291 0,11054559 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06389291 0,11046735 ! T cell proliferation GO:0042098 32 12 0,000 0,06389291 0,11038923 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06389291 0,11031121 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06389291 0,11023331 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06389291 0,11015552 ! drug transport GO:0015893 16 12 0,000 0,06389291 0,11007783 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06389291 0,11000026 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06389291 0,1099228 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06389291 0,10984544 ! focal adhesion formation GO:0048041 37 12 0,000 0,06389291 0,10976819 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06389291 0,10969105 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06389291 0,10961402 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06389291 0,1095371 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06389291 0,10946029 ! lipid digestion GO:0044241 21 12 0,000 0,06389291 0,10938358 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06389291 0,10930698 ! entry into host cell GO:0030260 34 12 0,000 0,06389291 0,10923049 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06389291 0,1091541 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06389291 0,10907783 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06389291 0,10900165 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06389291 0,10892559 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06389291 0,10884963 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06389291 0,10877378 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06389291 0,10869803 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06389291 0,10862239 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06389291 0,10854685 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06389291 0,10847142 ! fucose catabolic process GO:0019317 25 12 0,000 0,06389291 0,10839609 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06389291 0,10832087 ! histone acetylation GO:0016573 27 12 0,000 0,06389291 0,10824575 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06389291 0,10817073 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06389291 0,10809582 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06389291 0,10802102 ! zymogen activation GO:0031638 18 12 0,000 0,06389291 0,10794631 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,06389291 0,10787171 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06389291 0,10779722 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06389291 0,10772282 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06389291 0,10764853 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06389291 0,10757434 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06389291 0,10750025 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06389291 0,10742627 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06389291 0,10735239 ! defense response to fungus GO:0050832 15 12 0,000 0,06389291 0,1072786 ! developmental induction GO:0031128 22 12 0,000 0,06389291 0,10720492 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06389291 0,10713134 ! response to cold GO:0009409 17 12 0,000 0,06389291 0,10705787 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06389291 0,10698449 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06389291 0,10691121 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,06403711 0,10707916 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,0655375 0,10951308 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,0655375 0,10943823 ! learning or memory GO:0007611 161 76 1,000 0,0655375 0,10936347 ! amine catabolic process GO:0009310 136 77 1,000 0,06704964 0,11181042 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,06704964 0,11173415 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,06704964 0,11165798 ! monosaccharide catabolic process GO:0046365 125 77 1,000 0,06704964 0,11158192 ! regulation of catabolic process GO:0009894 173 77 1,000 0,06704964 0,11150596 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06903027 0,11472174 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06903027 0,11464375 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06903027 0,11456587 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06903027 0,11448809 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06903027 0,11441042 ! peroxisomal transport GO:0043574 28 13 0,000 0,06903027 0,11433285 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06903027 0,11425539 ! cartilage condensation GO:0001502 22 13 0,000 0,06903027 0,11417803 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06903027 0,11410078 ! organelle fusion GO:0048284 36 13 0,000 0,06903027 0,11402363 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06903027 0,11394659 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06903027 0,11386965 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06903027 0,11379282 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06903027 0,11371608 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06903027 0,11363946 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06903027 0,11356293 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06903027 0,11348651 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06903027 0,11341019 ! methionine metabolic process GO:0006555 31 13 0,000 0,06903027 0,11333397 ! plasma membrane organization GO:0007009 27 13 0,000 0,06903027 0,11325786 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06903027 0,11318185 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06903027 0,11310594 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06903027 0,11303013 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06903027 0,11295442 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06903027 0,11287882 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06903027 0,11280331 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06903027 0,11272791 ! exocrine system development GO:0035272 34 13 0,000 0,06903027 0,11265261 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06903027 0,11257741 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06903027 0,1125023 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06903027 0,1124273 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,06903027 0,1123524 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,06903027 0,1122776 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06903027 0,1122029 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06903027 0,11212829 ! protein homotetramerization GO:0051289 24 13 0,000 0,06903027 0,11205379 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06903027 0,11197938 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06903027 0,11190508 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06903027 0,11183087 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06903027 0,11175676 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06903027 0,11168275 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06903027 0,11160884 ! histone methylation GO:0016571 29 13 0,000 0,06903027 0,11153502 ! chromatin silencing GO:0006342 29 13 0,000 0,06903027 0,1114613 ! gland morphogenesis GO:0022612 31 13 0,000 0,06903027 0,11138768 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06903027 0,11131416 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06903027 0,11124073 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06903027 0,11116741 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06903027 0,11109417 ! spleen development GO:0048536 24 13 0,000 0,06903027 0,11102104 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06903027 0,110948 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06903027 0,11087505 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06903027 0,1108022 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06903027 0,11072945 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06903027 0,11065679 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06903027 0,11058423 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06903027 0,11051177 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06903027 0,11043939 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06903027 0,11036712 ! insulin secretion GO:0030073 24 13 0,000 0,06903027 0,11029493 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06903027 0,11022285 ! acrosome reaction GO:0007340 19 13 0,000 0,06903027 0,11015085 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06903027 0,11007895 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06903027 0,11000715 ! blood coagulation GO:0007596 151 79 1,000 0,07010841 0,11165244 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,07010841 0,1115797 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,07010841 0,11150705 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,0716547 0,11389229 ! meiosis GO:0007126 143 81 1,000 0,07321206 0,11629197 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,07321206 0,11621641 ! rRNA transcription GO:0009303 28 14 0,000 0,07413959 0,11761235 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07413959 0,11753602 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07413959 0,1174598 ! water transport GO:0006833 21 14 0,000 0,07413959 0,11738368 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07413959 0,11730765 ! non-recombinational repair GO:0000726 29 14 0,000 0,07413959 0,11723172 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07413959 0,11715589 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07413959 0,11708016 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07413959 0,11700453 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07413959 0,11692899 ! lipid localization GO:0010876 32 14 0,000 0,07413959 0,11685356 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07413959 0,11677822 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,07413959 0,11670297 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07413959 0,11662782 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07413959 0,11655277 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07413959 0,11647782 ! arginine metabolic process GO:0006525 21 14 0,000 0,07413959 0,11640296 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07413959 0,1163282 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07413959 0,11625354 ! regulation of heart rate GO:0002027 25 14 0,000 0,07413959 0,11617897 ! fear response GO:0042596 34 14 0,000 0,07413959 0,11610449 ! organic alcohol transport GO:0015850 29 14 0,000 0,07413959 0,11603012 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07413959 0,11595583 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07413959 0,11588165 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07413959 0,11580755 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07413959 0,11573355 ! bone mineralization GO:0030282 18 14 0,000 0,07413959 0,11565965 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07413959 0,11558584 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07413959 0,11551213 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07413959 0,1154385 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07413959 0,11536498 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07413959 0,11529154 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07413959 0,1152182 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07413959 0,11514495 ! ribosome assembly GO:0042255 18 14 0,000 0,07413959 0,1150718 ! cerebellum development GO:0021549 23 14 0,000 0,07413959 0,11499874 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07413959 0,11492577 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07413959 0,11485289 ! response to gamma radiation GO:0010332 30 14 0,000 0,07413959 0,11478011 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07413959 0,11470742 ! NADP metabolic process GO:0006739 24 14 0,000 0,07413959 0,11463482 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07413959 0,11456231 ! oxygen transport GO:0015671 22 14 0,000 0,07413959 0,11448989 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07413959 0,11441757 ! male genitalia development GO:0030539 26 14 0,000 0,07413959 0,11434534 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07413959 0,11427319 ! regulation of axon extension GO:0030516 43 14 0,000 0,07413959 0,11420114 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07413959 0,11412918 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,07478029 0,11504298 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,07478029 0,11497058 ! meiotic cell cycle GO:0051321 144 82 1,000 0,07478029 0,11489827 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,07635925 0,11725056 ! response to drug GO:0042493 149 83 1,000 0,07635925 0,11717691 ! inorganic anion transport GO:0015698 156 83 1,000 0,07635925 0,11710335 ! T cell activation GO:0042110 189 84 1,000 0,07794876 0,11946601 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07922101 0,12133976 ! lactation GO:0007595 30 15 0,000 0,07922101 0,12126373 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,07922101 0,1211878 ! reproductive cellular process GO:0048610 22 15 0,000 0,07922101 0,12111196 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07922101 0,12103622 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07922101 0,12096057 ! superoxide anion generation GO:0042554 22 15 0,000 0,07922101 0,12088502 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07922101 0,12080956 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07922101 0,1207342 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07922101 0,12065893 ! copper ion transport GO:0006825 22 15 0,000 0,07922101 0,12058375 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07922101 0,12050867 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07922101 0,12043368 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07922101 0,12035878 ! sulfate transport GO:0008272 27 15 0,000 0,07922101 0,12028398 ! response to cAMP GO:0051591 25 15 0,000 0,07922101 0,12020926 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07922101 0,12013465 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07922101 0,12006012 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07922101 0,11998569 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07922101 0,11991135 ! vesicle coating GO:0006901 38 15 0,000 0,07922101 0,1198371 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07922101 0,11976294 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07922101 0,11968888 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07922101 0,1196149 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07922101 0,11954102 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07922101 0,11946723 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07922101 0,11939353 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07922101 0,11931992 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07922101 0,11924641 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07922101 0,11917298 ! histone deacetylation GO:0016575 24 15 0,000 0,07922101 0,11909964 ! water homeostasis GO:0030104 28 15 0,000 0,07922101 0,11902639 ! cofactor transport GO:0051181 30 15 0,000 0,07922101 0,11895324 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07922101 0,11888017 ! muscle maintenance GO:0046716 26 15 0,000 0,07922101 0,11880719 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07922101 0,1187343 ! intestinal absorption GO:0050892 31 15 0,000 0,07922101 0,11866151 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07922101 0,1185888 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07922101 0,11851618 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07922101 0,11844365 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07922101 0,1183712 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07922101 0,11829885 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07922101 0,11822658 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07922101 0,11815441 ! actin filament polymerization GO:0030041 27 15 0,000 0,07922101 0,11808232 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07922101 0,11801031 ! hemostasis GO:0007599 165 85 1,000 0,07954867 0,11842621 ! negative regulation of growth GO:0045926 168 85 1,000 0,07954867 0,11835408 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,07954867 0,11828205 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,08115881 0,12060279 ! regulation of lyase activity GO:0051339 169 86 1,000 0,08115881 0,12052947 ! alcohol catabolic process GO:0046164 142 87 1,000 0,08277903 0,12286098 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08427468 0,12500488 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08427468 0,12492903 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08427468 0,12485327 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08427468 0,1247776 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08427468 0,12470202 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08427468 0,12462654 ! bone remodeling GO:0046849 28 16 0,000 0,08427468 0,12455114 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08427468 0,12447584 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08427468 0,12440063 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08427468 0,1243255 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08427468 0,12425047 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08427468 0,12417553 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08427468 0,12410068 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08427468 0,12402593 ! startle response GO:0001964 28 16 0,000 0,08427468 0,12395126 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08427468 0,12387668 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08427468 0,12380219 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08427468 0,12372779 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08427468 0,12365348 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08427468 0,12357925 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08427468 0,12350512 ! pituitary gland development GO:0021983 30 16 0,000 0,08427468 0,12343108 ! lysosomal transport GO:0007041 31 16 0,000 0,08427468 0,12335712 ! fructose metabolic process GO:0006000 25 16 0,000 0,08427468 0,12328326 ! L-amino acid transport GO:0015807 33 16 0,000 0,08427468 0,12320948 ! stem cell development GO:0048864 46 16 0,000 0,08427468 0,12313579 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08427468 0,12306219 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08427468 0,12298867 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08427468 0,12291525 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08427468 0,12284191 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08427468 0,12276866 ! axon cargo transport GO:0008088 46 16 0,000 0,08427468 0,12269549 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08427468 0,12262242 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08427468 0,12254943 ! DNA replication initiation GO:0006270 28 16 0,000 0,08427468 0,12247652 ! neuron recognition GO:0008038 40 16 0,000 0,08427468 0,12240371 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08427468 0,12233098 ! tissue regeneration GO:0042246 27 16 0,000 0,08427468 0,12225834 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08427468 0,12218578 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08427468 0,12211331 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08427468 0,12204092 ! biomineral formation GO:0031214 22 16 0,000 0,08427468 0,12196862 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08427468 0,12189641 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08427468 0,12182428 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08427468 0,12175224 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08427468 0,12168028 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08427468 0,12160841 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08427468 0,12153662 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08427468 0,12146492 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08427468 0,1213933 ! peptide hormone processing GO:0016486 27 16 0,000 0,08427468 0,12132177 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,08440917 0,12144382 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,08604907 0,12373036 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,08769858 0,12602801 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08930075 0,12825499 ! metencephalon development GO:0022037 32 17 0,000 0,08930075 0,12817964 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08930075 0,12810437 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,08930075 0,12802919 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08930075 0,1279541 ! filopodium assembly GO:0046847 42 17 0,000 0,08930075 0,1278791 ! endothelial cell migration GO:0043542 31 17 0,000 0,08930075 0,12780418 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08930075 0,12772936 ! glial cell development GO:0021782 28 17 0,000 0,08930075 0,12765462 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08930075 0,12757997 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08930075 0,1275054 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08930075 0,12743092 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08930075 0,12735653 ! myoblast differentiation GO:0045445 50 17 0,000 0,08930075 0,12728223 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08930075 0,12720801 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,08930075 0,12713388 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08930075 0,12705984 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08930075 0,12698588 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08930075 0,12691201 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08930075 0,12683822 ! membrane budding GO:0006900 42 17 0,000 0,08930075 0,12676452 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08930075 0,12669091 ! regulation of protein binding GO:0043393 33 17 0,000 0,08930075 0,12661738 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08930075 0,12654393 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08930075 0,12647057 ! genitalia development GO:0048806 32 17 0,000 0,08930075 0,1263973 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08930075 0,12632411 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08930075 0,12625101 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08930075 0,12617799 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,08930075 0,12610505 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08930075 0,1260322 ! steroid catabolic process GO:0006706 34 17 0,000 0,08930075 0,12595943 ! gas transport GO:0015669 26 17 0,000 0,08930075 0,12588675 ! organic cation transport GO:0015695 32 17 0,000 0,08930075 0,12581415 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08930075 0,12574164 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08930075 0,12566921 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08930075 0,12559686 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,08935754 0,12560441 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,08935754 0,12553218 ! defense response to bacterium GO:0042742 112 91 1,000 0,08935754 0,12546003 ! bone development GO:0060348 206 92 1,000 0,0910258 0,1277289 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09429938 0,1322465 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09429938 0,13217062 ! limbic system development GO:0021761 40 18 0,000 0,09429938 0,13209484 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09429938 0,13201914 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09429938 0,13194353 ! adult walking behavior GO:0007628 36 18 0,000 0,09429938 0,131868 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09429938 0,13179256 ! heart looping GO:0001947 34 18 0,000 0,09429938 0,13171721 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09429938 0,13164194 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09429938 0,13156676 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09429938 0,13149166 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09429938 0,13141665 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,09429938 0,13134173 ! glycine metabolic process GO:0006544 30 18 0,000 0,09429938 0,13126689 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09429938 0,13119214 ! response to retinoic acid GO:0032526 31 18 0,000 0,09429938 0,13111747 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,09429938 0,13104289 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09429938 0,13096839 ! DNA integration GO:0015074 32 18 0,000 0,09429938 0,13089397 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09429938 0,13081965 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09429938 0,1307454 ! neural crest cell migration GO:0001755 41 18 0,000 0,09429938 0,13067124 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09429938 0,13059716 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09429938 0,13052317 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09429938 0,13044926 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09429938 0,13037544 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09429938 0,13030169 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09429938 0,13022804 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,09429938 0,13015446 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09429938 0,13008097 ! detection of bacterium GO:0016045 22 18 0,000 0,09429938 0,13000756 ! defense response to virus GO:0051607 43 18 0,000 0,09429938 0,12993423 ! microspike assembly GO:0030035 46 18 0,000 0,09429938 0,12986099 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09429938 0,12978783 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09429938 0,12971475 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,09438962 0,12976581 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,09608489 0,13202215 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,09608489 0,13194794 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,09608489 0,13187381 ! response to protein stimulus GO:0051789 158 96 1,000 0,09778886 0,13413711 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09927072 0,13609336 ! positive regulation of translation GO:0045727 31 19 0,000 0,09927072 0,13601703 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09927072 0,13594079 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09927072 0,13586463 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,09927072 0,13578856 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09927072 0,13571257 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09927072 0,13563667 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09927072 0,13556085 ! inositol metabolic process GO:0006020 33 19 0,000 0,09927072 0,13548512 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09927072 0,13540947 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09927072 0,13533391 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09927072 0,13525843 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09927072 0,13518304 ! cerebral cortex development GO:0021987 40 19 0,000 0,09927072 0,13510772 ! pigmentation during development GO:0048066 42 19 0,000 0,09927072 0,1350325 ! response to vitamin A GO:0033189 32 19 0,000 0,09927072 0,13495735 ! heme metabolic process GO:0042168 40 19 0,000 0,09927072 0,13488229 ! neuromuscular junction development GO:0007528 43 19 0,000 0,09927072 0,13480732 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,09927072 0,13473242 ! response to fungus GO:0009620 26 19 0,000 0,09927072 0,13465762 ! protein export from nucleus GO:0006611 40 19 0,000 0,09927072 0,13458289 ! heart process GO:0003015 32 19 0,000 0,09927072 0,13450824 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09927072 0,13443368 ! visual learning GO:0008542 38 19 0,000 0,09927072 0,1343592 ! cellular pigmentation GO:0033059 37 19 0,000 0,09927072 0,13428481 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09927072 0,1342105 ! vitamin transport GO:0051180 31 19 0,000 0,09927072 0,13413626 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09927072 0,13406211 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09927072 0,13398805 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09927072 0,13391406 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09927072 0,13384016 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09927072 0,13376633 ! cilium assembly GO:0042384 38 19 0,000 0,09927072 0,13369259 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09927072 0,13361893 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,10122235 0,13617081 ! protein secretion GO:0009306 45 20 0,000 0,1042149 0,14011943 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1042149 0,14004236 ! positive regulation of ossification GO:0045778 50 20 0,000 0,1042149 0,13996537 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,1042149 0,13988847 ! skin development GO:0043588 42 20 0,000 0,1042149 0,13981165 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,1042149 0,13973491 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,1042149 0,13965826 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,1042149 0,13958169 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1042149 0,13950521 ! response to vitamin GO:0033273 36 20 0,000 0,1042149 0,13942881 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,1042149 0,1393525 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,1042149 0,13927626 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,1042149 0,13920012 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1042149 0,13912405 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1042149 0,13904807 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1042149 0,13897217 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,1042149 0,13889635 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1042149 0,13882062 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,1042149 0,13874497 ! actin filament bundle formation GO:0051017 47 20 0,000 0,1042149 0,1386694 ! body fluid secretion GO:0007589 33 20 0,000 0,1042149 0,13859391 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,1042149 0,1385185 ! peptide secretion GO:0002790 38 20 0,000 0,1042149 0,13844318 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1042149 0,13836794 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,1042149 0,13829278 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1042149 0,1382177 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1042149 0,13814271 ! cell-cell junction organization GO:0045216 43 20 0,000 0,1042149 0,13806779 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,1042149 0,13799296 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1042149 0,13791821 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,1042149 0,13784354 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,1042149 0,13776895 ! regulation of glucose import GO:0046324 30 20 0,000 0,1042149 0,13769444 GO:0010827|regulation of glucose transport, ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1042149 0,13762001 ! negative regulation of translation GO:0017148 32 20 0,000 0,1042149 0,13754566 ! regulation of cell killing GO:0031341 46 21 0,000 0,10913209 0,14395772 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10913209 0,14388003 ! hormone secretion GO:0046879 39 21 0,000 0,10913209 0,14380242 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10913209 0,1437249 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10913209 0,14364747 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10913209 0,14357011 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10913209 0,14349284 ! ovarian follicle development GO:0001541 39 21 0,000 0,10913209 0,14341565 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10913209 0,14333855 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10913209 0,14326152 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10913209 0,14318458 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10913209 0,14310773 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10913209 0,14303095 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10913209 0,14295426 ! sensory perception of pain GO:0019233 33 21 0,000 0,10913209 0,14287765 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10913209 0,14280112 ! diencephalon development GO:0021536 36 21 0,000 0,10913209 0,14272468 ! collagen fibril organization GO:0030199 62 21 0,000 0,10913209 0,14264831 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,10913209 0,14257203 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,10913209 0,14249583 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,10913209 0,14241971 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10913209 0,14234367 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10913209 0,14226771 ! collagen catabolic process GO:0030574 29 21 0,000 0,10913209 0,14219184 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10913209 0,14211604 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10913209 0,14204033 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10913209 0,14196469 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,10913209 0,14188914 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11402242 0,1481685 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11402242 0,14808973 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11402242 0,14801104 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11402242 0,14793243 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11402242 0,14785391 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11402242 0,14777548 ! microtubule-based transport GO:0010970 59 22 0,000 0,11402242 0,14769712 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,11402242 0,14761885 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11402242 0,14754066 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11402242 0,14746256 ! vacuolar transport GO:0007034 41 22 0,000 0,11402242 0,14738454 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11402242 0,1473066 ! fucose metabolic process GO:0006004 44 22 0,000 0,11402242 0,14722874 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11402242 0,14715096 ! ureteric bud development GO:0001657 50 22 0,000 0,11402242 0,14707327 ! cell aging GO:0007569 48 22 0,000 0,11402242 0,14699566 ! stem cell differentiation GO:0048863 57 22 0,000 0,11402242 0,14691813 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11402242 0,14684068 ! cytolysis GO:0019835 27 22 0,000 0,11402242 0,14676332 ! renal system process GO:0003014 42 22 0,000 0,11402242 0,14668603 ! vasodilation GO:0042311 40 22 0,000 0,11402242 0,14660883 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11402242 0,14653171 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,11402242 0,14645467 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11402242 0,14637771 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11402242 0,14630083 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,11402242 0,14622403 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11402242 0,14614731 ! sarcomere organization GO:0045214 32 22 0,000 0,11402242 0,14607067 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11402242 0,14599412 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11402242 0,14591764 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11402242 0,14584124 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11402242 0,14576493 ! gut development GO:0048565 44 22 0,000 0,11402242 0,14568869 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11402242 0,14561253 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,11402242 0,14553646 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11402242 0,14546046 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,11888604 0,15158591 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11888604 0,15150684 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11888604 0,15142785 ! gluconeogenesis GO:0006094 38 23 0,000 0,11888604 0,15134894 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11888604 0,15127011 ! viral genome replication GO:0019079 44 23 0,000 0,11888604 0,15119136 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11888604 0,1511127 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,11888604 0,15103412 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11888604 0,15095562 ! regeneration GO:0031099 42 23 0,000 0,11888604 0,1508772 ! axis specification GO:0009798 43 23 0,000 0,11888604 0,15079886 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11888604 0,15072061 ! response to ethanol GO:0045471 47 23 0,000 0,11888604 0,15064243 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11888604 0,15056434 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11888604 0,15048632 ! peroxisome organization GO:0007031 43 23 0,000 0,11888604 0,15040839 ! lysosome organization GO:0007040 47 23 0,000 0,11888604 0,15033054 ! vesicle targeting GO:0006903 49 23 0,000 0,11888604 0,15025277 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,11888604 0,15017508 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11888604 0,15009747 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11888604 0,15001994 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11888604 0,14994249 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11888604 0,14986512 ! fatty acid transport GO:0015908 47 23 0,000 0,11888604 0,14978783 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11888604 0,14971062 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11888604 0,14963349 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11888604 0,14955644 ! hormone transport GO:0009914 41 23 0,000 0,11888604 0,14947947 ! cell-cell recognition GO:0009988 28 23 0,000 0,11888604 0,14940258 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11888604 0,14932576 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11888604 0,14924903 GO:0006099|tricarboxylic acid cycle, ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,1237231 0,15524168 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,1237231 0,15516198 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,1237231 0,15508237 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,1237231 0,15500284 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,1237231 0,1549234 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,1237231 0,15484403 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,1237231 0,15476474 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,1237231 0,15468554 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,1237231 0,15460642 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,1237231 0,15452737 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,1237231 0,15444841 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,1237231 0,15436953 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,1237231 0,15429073 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,1237231 0,15421201 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,1237231 0,15413337 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,1237231 0,15405481 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,1237231 0,15397633 ! pallium development GO:0021543 56 24 0,000 0,1237231 0,15389794 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,1237231 0,15381962 ! platelet activation GO:0030168 41 24 0,000 0,1237231 0,15374138 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,1237231 0,15366322 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,1237231 0,15358513 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,1237231 0,15350713 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,1237231 0,15342921 ! regulation of amine transport GO:0051952 41 24 0,000 0,1237231 0,15335137 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,1237231 0,1532736 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,12853375 0,15915253 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12853375 0,15907191 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12853375 0,15899136 ! leukocyte adhesion GO:0007159 55 25 0,000 0,12853375 0,1589109 ! phototransduction GO:0007602 37 25 0,000 0,12853375 0,15883052 ! keratinization GO:0031424 37 25 0,000 0,12853375 0,15875022 ! vasculogenesis GO:0001570 49 25 0,000 0,12853375 0,15867001 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,12853375 0,15858987 ! vacuole organization GO:0007033 49 25 0,000 0,12853375 0,15850981 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12853375 0,15842984 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,12853375 0,15834995 ! chromosome condensation GO:0030261 48 25 0,000 0,12853375 0,15827013 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,12853375 0,1581904 ! regulation of behavior GO:0050795 48 25 0,000 0,12853375 0,15811075 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12853375 0,15803117 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12853375 0,15795168 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12853375 0,15787227 ! immunoglobulin production GO:0002377 62 25 0,000 0,12853375 0,15779294 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12853375 0,15771368 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12853375 0,15763451 ! liver development GO:0001889 55 25 0,000 0,12853375 0,15755542 ! protein tetramerization GO:0051262 57 25 0,000 0,12853375 0,1574764 ! myelination GO:0042552 50 26 0,000 0,13331811 0,16325622 ! initiation of viral infection GO:0019059 60 26 0,000 0,13331811 0,16317442 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13331811 0,16309271 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13331811 0,16301109 ! molting cycle process GO:0022404 52 26 0,000 0,13331811 0,16292954 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13331811 0,16284808 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,13331811 0,16276669 GO:0006479|protein amino acid methylation, ! spinal cord development GO:0021510 54 26 0,000 0,13331811 0,16268539 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13331811 0,16260417 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13331811 0,16252303 ! digestive system process GO:0022600 49 26 0,000 0,13331811 0,16244197 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13331811 0,16236099 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13331811 0,1622801 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13331811 0,16219928 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,13331811 0,16211854 ! neural crest cell development GO:0014032 59 26 0,000 0,13331811 0,16203789 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13331811 0,16195731 ! negative regulation of cell development GO:0010721 83 26 0,000 0,13331811 0,16187681 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13331811 0,1617964 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13331811 0,16171606 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13331811 0,16163581 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13331811 0,16155563 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13331811 0,16147553 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,13331811 0,16139552 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13331811 0,16131558 ! blastocyst development GO:0001824 50 26 0,000 0,13331811 0,16123572 ! telomere organization GO:0032200 46 26 0,000 0,13331811 0,16115594 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13331811 0,16107624 ! neural tube closure GO:0001843 58 26 0,000 0,13331811 0,16099661 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,13331811 0,16091707 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13331811 0,16083761 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13331811 0,16075822 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13807635 0,16641367 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13807635 0,16633162 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13807635 0,16624964 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13807635 0,16616774 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13807635 0,16608593 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13807635 0,16600419 ! iron ion transport GO:0006826 65 27 0,000 0,13807635 0,16592254 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,13807635 0,16584096 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13807635 0,16575947 ! tube lumen formation GO:0035148 59 27 0,000 0,13807635 0,16567805 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13807635 0,16559672 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,13807635 0,16551546 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,13807635 0,16543429 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13807635 0,16535319 ! response to toxin GO:0009636 49 27 0,000 0,13807635 0,16527218 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13807635 0,16519124 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13807635 0,16511039 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,14280859 0,17068561 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,14280859 0,17060215 ! protein amino acid acylation GO:0043543 59 28 0,000 0,14280859 0,17051876 ! vesicle docking GO:0048278 55 28 0,000 0,14280859 0,17043546 ! circadian rhythm GO:0007623 56 28 0,000 0,14280859 0,17035224 ! dendrite development GO:0016358 67 28 0,000 0,14280859 0,1702691 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,14280859 0,17018604 ! fat cell differentiation GO:0045444 57 28 0,000 0,14280859 0,17010307 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,14280859 0,17002017 ! sperm motility GO:0030317 37 28 0,000 0,14280859 0,16993735 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,14280859 0,16985462 ! base-excision repair GO:0006284 41 28 0,000 0,14280859 0,16977197 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,14280859 0,16968939 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,14280859 0,1696069 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,14280859 0,16952448 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,14280859 0,16944215 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,14280859 0,1693599 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,14280859 0,16927772 ! glutathione metabolic process GO:0006749 42 28 0,000 0,14280859 0,16919563 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,14280859 0,16911362 ! lipid oxidation GO:0034440 48 28 0,000 0,14280859 0,16903168 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,14280859 0,16894983 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,14280859 0,16886805 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,14751499 0,17434887 ! translational initiation GO:0006413 66 29 0,000 0,14751499 0,17426456 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14751499 0,17418033 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14751499 0,17409619 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,14751499 0,17401213 ! autophagy GO:0006914 47 29 0,000 0,14751499 0,17392814 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14751499 0,17384424 ! primary neural tube formation GO:0014020 61 29 0,000 0,14751499 0,17376042 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,14751499 0,17367668 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,14751499 0,17359302 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,14751499 0,17350944 ! somitogenesis GO:0001756 52 29 0,000 0,14751499 0,17342594 ! synaptogenesis GO:0007416 46 29 0,000 0,14751499 0,17334253 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,14751499 0,17325919 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14751499 0,17317593 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14751499 0,17309275 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,15219567 0,17849929 ! phenol metabolic process GO:0018958 56 30 0,000 0,15219567 0,17841364 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,15219567 0,17832807 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,15219567 0,17824258 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,15219567 0,17815718 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,15219567 0,17807185 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,15219567 0,17798661 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,15219567 0,17790145 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,15219567 0,17781637 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,15219567 0,17773137 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,15219567 0,17764645 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,15219567 0,17756162 ! cell fate determination GO:0001709 64 30 0,000 0,15219567 0,17747686 ! phospholipid transport GO:0015914 65 30 0,000 0,15219567 0,17739219 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,15219567 0,1773076 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,15219567 0,17722308 GO:0046496|nicotinamide nucleotide metabolic process, ! tissue homeostasis GO:0001894 50 30 0,000 0,15219567 0,17713865 GO:0048871|multicellular organismal homeostasis, ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15685079 0,18246975 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15685079 0,1823829 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15685079 0,18229614 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15685079 0,18220945 ! cell junction assembly GO:0034329 85 31 0,000 0,15685079 0,18212285 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15685079 0,18203633 ! ovulation cycle process GO:0022602 55 31 0,000 0,15685079 0,1819499 ! peptide transport GO:0015833 60 31 0,000 0,15685079 0,18186354 ! male gonad development GO:0008584 56 31 0,000 0,15685079 0,18177727 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,15685079 0,18169108 ! detection of light stimulus GO:0009583 44 31 0,000 0,15685079 0,18160497 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,15685079 0,18151894 ! natural killer cell activation GO:0030101 50 31 0,000 0,15685079 0,18143299 ! ensheathment of neurons GO:0007272 64 31 0,000 0,15685079 0,18134713 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,15685079 0,18126134 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15685079 0,18117564 ! eye morphogenesis GO:0048592 65 31 0,000 0,15685079 0,18109002 ! response to heat GO:0009408 54 31 0,000 0,15685079 0,18100448 ! collagen metabolic process GO:0032963 49 32 0,000 0,16148048 0,18625912 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,16148048 0,18617122 ! spindle organization GO:0007051 50 32 0,000 0,16148048 0,1860834 ! metanephros development GO:0001656 81 32 0,000 0,16148048 0,18599567 ! mesoderm formation GO:0001707 73 32 0,000 0,16148048 0,18590802 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,16148048 0,18582045 ! ovulation cycle GO:0042698 57 32 0,000 0,16148048 0,18573296 ! BMP signaling pathway GO:0030509 71 32 0,000 0,16148048 0,18564556 ! hindbrain development GO:0030902 65 32 0,000 0,16148048 0,18555824 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,16148048 0,185471 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,16148048 0,18538384 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,16148048 0,18529676 ! regulation of pH GO:0006885 56 33 0,000 0,16608487 0,19049077 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,16608487 0,19040138 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16608487 0,19031208 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16608487 0,19022285 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,16608487 0,19013371 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16608487 0,19004466 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,16608487 0,18995569 ! response to ionizing radiation GO:0010212 74 33 0,000 0,16608487 0,1898668 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,16608487 0,18977799 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16608487 0,18968927 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,16608487 0,18960063 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16608487 0,18951207 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,16608487 0,1894236 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,16608487 0,18933521 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,17066412 0,19446476 ! post-embryonic development GO:0009791 76 34 0,000 0,17066412 0,1943741 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,17066412 0,19428352 ! cholesterol transport GO:0030301 62 34 0,000 0,17066412 0,19419303 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,17066412 0,19410262 ! spliceosome assembly GO:0000245 75 34 0,000 0,17066412 0,1940123 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,17066412 0,19392206 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,17066412 0,19383191 ! formation of primary germ layer GO:0001704 76 34 0,000 0,17066412 0,19374184 ! cell fate specification GO:0001708 56 34 0,000 0,17066412 0,19365185 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,17066412 0,19356195 ! adult locomotory behavior GO:0008344 62 34 0,000 0,17066412 0,19347213 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,17521834 0,19854286 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,17521834 0,19845081 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,17521834 0,19835885 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,17521834 0,19826698 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,17521834 0,19817519 ! membrane docking GO:0022406 69 35 0,000 0,17521834 0,19808348 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,17521834 0,19799186 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,17521834 0,19790033 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,17521834 0,19780887 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,17521834 0,19771751 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,17521834 0,19762623 ! ceramide metabolic process GO:0006672 72 35 0,000 0,17521834 0,19753503 ! telencephalon development GO:0021537 81 35 0,000 0,17521834 0,19744391 ! sterol transport GO:0015918 63 35 0,000 0,17521834 0,19735288 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,17521834 0,19726194 ! placenta development GO:0001890 53 35 0,000 0,17521834 0,19717108 ! vesicle localization GO:0051648 70 35 0,000 0,17521834 0,1970803 ! regulation of muscle development GO:0048634 82 36 0,000 0,17974768 0,20208172 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,17974768 0,20198877 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17974768 0,2018959 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17974768 0,20180312 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17974768 0,20171042 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17974768 0,20161781 ! regulation of proteolysis GO:0030162 77 36 0,000 0,17974768 0,20152528 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,17974768 0,20143284 ! aerobic respiration GO:0009060 56 36 0,000 0,17974768 0,20134048 ! embryonic organ development GO:0048568 67 36 0,000 0,17974768 0,20124821 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17974768 0,20115602 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17974768 0,20106391 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,18425228 0,20600838 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,18425228 0,20591414 ! sister chromatid segregation GO:0000819 65 37 0,000 0,18425228 0,20581999 ! odontogenesis GO:0042476 74 37 0,000 0,18425228 0,20572592 ! cell junction organization GO:0034330 96 37 0,000 0,18425228 0,20563194 ! tissue remodeling GO:0048771 78 37 0,000 0,18425228 0,20553804 ! female gonad development GO:0008585 71 37 0,000 0,18425228 0,20544423 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,18425228 0,20535051 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,18425228 0,20525687 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,18873226 0,21015174 ! meiosis I GO:0007127 74 38 0,000 0,18873226 0,210056 ! organic anion transport GO:0015711 82 38 0,000 0,18873226 0,20996035 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18873226 0,20986478 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,18873226 0,2097693 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18873226 0,20967391 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,18873226 0,2095786 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18873226 0,20948338 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18873226 0,20938825 ! spermatid development GO:0007286 69 38 0,000 0,18873226 0,2092932 ! glycogen metabolic process GO:0005977 63 38 0,000 0,18873226 0,20919824 ! pigment metabolic process GO:0042440 87 38 0,000 0,18873226 0,20910336 ! neural tube formation GO:0001841 79 38 0,000 0,18873226 0,20900858 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,19318777 0,21384582 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,19318777 0,21374897 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,19318777 0,2136522 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,19318777 0,21355553 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 0,000 0,19318777 0,21345894 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,19318777 0,21336244 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,19318777 0,21326603 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,19318777 0,2131697 ! glucan metabolic process GO:0044042 64 39 0,000 0,19318777 0,21307346 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 0,000 0,19761893 0,21786239 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,19761893 0,21776412 ! learning GO:0007612 82 40 0,000 0,19761893 0,21766594 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,19761893 0,21756784 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,19761893 0,21746984 ! mismatch repair GO:0006298 58 40 0,000 0,19761893 0,21737193 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,19761893 0,2172741 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,19761893 0,21717636 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,19761893 0,21707871 ! RNA export from nucleus GO:0006405 61 41 0,000 0,20202588 0,22181988 ! mRNA catabolic process GO:0006402 79 41 0,000 0,20202588 0,22172023 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,20202588 0,22162067 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,20202588 0,2215212 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,20202588 0,22142181 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,20202588 0,22132252 ! feeding behavior GO:0007631 69 41 0,000 0,20202588 0,22122332 ! mesenchymal cell development GO:0014031 94 41 0,000 0,20202588 0,2211242 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,20202588 0,22102518 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,20202588 0,22092624 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,20202588 0,22082739 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,20202588 0,22072863 ! RNA modification GO:0009451 64 41 0,000 0,20202588 0,22062996 ! organic ether metabolic process GO:0018904 59 42 0,000 0,20640875 0,22531571 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,20640875 0,22521508 ! T cell differentiation GO:0030217 93 42 0,000 0,20640875 0,22511454 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,20640875 0,22501409 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,20640875 0,22491372 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,20640875 0,22481345 ! cytokinesis GO:0000910 84 42 0,000 0,20640875 0,22471327 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,20640875 0,22461317 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,21076766 0,22925441 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,21076766 0,22915238 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,21076766 0,22905045 ! regulation of tube size GO:0035150 76 43 0,000 0,21076766 0,2289486 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,21076766 0,22884685 ! glucose transport GO:0015758 66 43 0,000 0,21076766 0,22874518 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,21076766 0,22864361 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,21076766 0,22854212 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,21076766 0,22844073 ! segmentation GO:0035282 78 43 0,000 0,21076766 0,22833943 ! ion transmembrane transport GO:0034220 79 43 0,000 0,21076766 0,22823821 ! neuron migration GO:0001764 85 43 0,000 0,21076766 0,22813709 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,21510276 0,23272633 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,21510276 0,23262331 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,21510276 0,23252038 ! hexose transport GO:0008645 68 44 0,000 0,21510276 0,23241754 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,21510276 0,23231479 ! phagocytosis GO:0006909 105 44 0,000 0,21510276 0,23221213 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,21510276 0,23210956 ! double-strand break repair GO:0006302 85 44 0,000 0,21510276 0,23200709 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,21941417 0,23655288 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,21941417 0,23644853 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,21941417 0,23634428 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,21941417 0,23624011 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,21941417 0,23613604 ! polyol metabolic process GO:0019751 77 45 0,000 0,21941417 0,23603206 ! developmental growth GO:0048589 88 45 0,000 0,21941417 0,23592818 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,22370202 0,24043292 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,22370202 0,24032719 ! leukocyte migration GO:0050900 75 46 0,000 0,22370202 0,24022155 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,22370202 0,240116 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,22370202 0,24001055 ! cell growth GO:0016049 90 46 0,000 0,22370202 0,23990519 ! neural tube development GO:0021915 91 47 0,000 0,22796643 0,24437121 ! positive regulation of defense response GO:0031349 88 48 0,000 0,23220753 0,24880834 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,23220753 0,24869926 ! mitochondrial transport GO:0006839 94 48 0,000 0,23220753 0,24859027 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,23220753 0,24848139 ! male sex differentiation GO:0046661 93 48 0,000 0,23220753 0,24837259 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,23220753 0,2482639 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,23220753 0,2481553 ! response to calcium ion GO:0051592 94 49 0,000 0,23642546 0,25255243 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,23642546 0,25244205 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,23642546 0,25233176 ! JNK cascade GO:0007254 106 49 0,000 0,23642546 0,25222157 ! regulation of action potential GO:0001508 102 50 0,000 0,24062033 0,25658467 ! regulation of ion transport GO:0043269 86 50 0,000 0,24062033 0,25647272 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,24062033 0,25636087 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,24062033 0,25624912 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,24479228 0,26057845 ! viral infectious cycle GO:0019058 104 51 0,000 0,24479228 0,26046496 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,24479228 0,26035156 ! peptide metabolic process GO:0006518 80 51 0,000 0,24479228 0,26023827 ! response to temperature stimulus GO:0009266 84 51 0,000 0,24479228 0,26012507 ! Notch signaling pathway GO:0007219 111 52 0,000 0,24894142 0,26441908 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,24894142 0,26430417 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,24894142 0,26418935 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,24894142 0,26407464 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,24894142 0,26396002 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,24894142 0,26384551 ! histone modification GO:0016570 104 52 0,000 0,24894142 0,26373109 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,24894142 0,26361677 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,24894142 0,26350255 ! amino acid activation GO:0043038 98 52 0,000 0,24894142 0,26338843 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,25306789 0,26763846 ! inner ear development GO:0048839 89 53 0,000 0,25306789 0,26752265 ! chromatin remodeling GO:0006338 122 53 0,000 0,25306789 0,26740694 ! vesicle organization GO:0016050 127 53 0,000 0,25306789 0,26729133 ! cartilage development GO:0051216 99 53 0,000 0,25306789 0,26717582 ! synapse organization GO:0050808 102 53 0,000 0,25306789 0,26706041 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,25717179 0,27127405 ! regulation of translational initiation GO:0006446 87 54 0,000 0,25717179 0,27115697 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,25717179 0,27103999 ! neuromuscular process GO:0050905 107 54 0,000 0,25717179 0,27092311 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,25717179 0,27080633 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,25717179 0,27068965 ! membrane fusion GO:0006944 122 54 0,000 0,25717179 0,27057308 ! covalent chromatin modification GO:0016569 115 54 0,000 0,25717179 0,2704566 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,25717179 0,27034023 ! regulation of cell shape GO:0008360 142 54 0,000 0,25717179 0,27022395 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,25717179 0,27010778 ! RNA catabolic process GO:0006401 103 55 0,000 0,26125327 0,27427663 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,26125327 0,27415882 ! cell recognition GO:0008037 98 55 0,000 0,26125327 0,2740411 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,26125327 0,27392349 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,26531243 0,27806017 ! heart morphogenesis GO:0003007 105 57 0,000 0,2693494 0,28217006 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,2733643 0,28625332 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,2733643 0,28613067 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,2733643 0,28600813 ! aging GO:0007568 112 58 0,000 0,2733643 0,2858857 ! gastrulation GO:0007369 122 58 0,000 0,2733643 0,28576337 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,2733643 0,28564114 ! nuclear export GO:0051168 110 59 0,000 0,27735726 0,28968952 ! establishment of organelle localization GO:0051656 122 59 0,000 0,27735726 0,28956572 ! regulation of endocytosis GO:0030100 104 60 0,000 0,28132838 0,29358618 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,28132838 0,29346082 ! adult behavior GO:0030534 104 60 0,000 0,28132838 0,29333557 ! kidney development GO:0001822 133 60 0,000 0,28132838 0,29321043 ! positive regulation of secretion GO:0051047 110 61 0,000 0,28527779 0,29719985 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,28527779 0,29707317 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,28527779 0,29694659 ! regulation of heart contraction GO:0008016 123 61 0,000 0,28527779 0,29682012 ! camera-type eye development GO:0043010 126 61 0,000 0,28527779 0,29669376 ! proton transport GO:0015992 117 61 0,000 0,28527779 0,29656751 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,28527779 0,29644137 ! viral reproductive process GO:0022415 132 62 0,000 0,28920561 0,30039512 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,28920561 0,30026745 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,28920561 0,3001399 ! tRNA processing GO:0008033 102 62 0,000 0,28920561 0,30001245 ! regulation of mitosis GO:0007088 112 63 0,000 0,29311196 0,3039357 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,29311196 0,30380675 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,29311196 0,30367791 ! hydrogen transport GO:0006818 121 64 0,000 0,29699694 0,3075725 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,29699694 0,30744218 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,30086069 0,31130989 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,30086069 0,31117809 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,30086069 0,31104641 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,30086069 0,31091483 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,3047033 0,31475271 ! gonad development GO:0008406 115 66 0,000 0,3047033 0,31461968 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,30852491 0,31843107 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,30852491 0,3182966 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,30852491 0,31816224 ! secondary metabolic process GO:0019748 125 67 0,000 0,30852491 0,31802799 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,30852491 0,31789386 ! viral reproduction GO:0016032 142 68 0,000 0,31232561 0,32167431 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,31610553 0,32543018 ! lung development GO:0030324 165 69 0,000 0,31610553 0,3252931 ! urogenital system development GO:0001655 149 69 0,000 0,31610553 0,32515613 ! single fertilization GO:0007338 83 69 0,000 0,31610553 0,32501928 ! cell redox homeostasis GO:0045454 114 70 0,000 0,31986478 0,32874618 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,32360348 0,33244882 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,32360348 0,33230908 ! appendage morphogenesis GO:0035107 150 72 0,000 0,32732172 0,33598612 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,32732172 0,33584501 ! respiratory tube development GO:0030323 171 72 0,000 0,32732172 0,33570402 ! B cell activation GO:0042113 179 72 0,000 0,32732172 0,33556314 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,32732172 0,33542239 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,32732172 0,33528175 ! appendage development GO:0048736 151 73 0,000 0,33101963 0,33892748 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,33101963 0,33878549 ! amino acid transport GO:0006865 148 74 0,000 0,33469732 0,34240601 ! respiratory system development GO:0060541 175 74 0,000 0,33469732 0,34226268 ! transition metal ion transport GO:0000041 143 75 0,000 0,33835489 0,34585816 ! reproductive structure development GO:0048608 131 75 0,000 0,33835489 0,34571351 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,33835489 0,34556898 ! eye development GO:0001654 155 75 0,000 0,33835489 0,34542457 ! axon guidance GO:0007411 162 75 0,000 0,33835489 0,34528028 ! rhythmic process GO:0048511 142 75 0,000 0,33835489 0,34513611 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,34199245 0,34870099 ! regulation of blood pressure GO:0008217 134 76 0,000 0,34199245 0,34855551 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,34199245 0,34841016 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,34561012 0,35194895 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,34561012 0,3518023 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,349208 0,3553166 ! antigen processing and presentation GO:0019882 117 78 0,000 0,349208 0,35516867 ! fertilization GO:0009566 99 78 0,000 0,349208 0,35502087 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,3527862 0,35850944 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,35634483 0,36197523 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,35634483 0,36182478 ! response to hypoxia GO:0001666 178 81 0,000 0,35988399 0,36526655 ! response to oxygen levels GO:0070482 183 83 0,000 0,36690433 0,37223724 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,36690433 0,37208272 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,36690433 0,37192833 ! response to metal ion GO:0010038 158 84 0,000 0,37038572 0,37530167 ! response to nutrient GO:0007584 135 84 0,000 0,37038572 0,37514607 ! digestion GO:0007586 130 84 0,000 0,37038572 0,3749906 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,37384807 0,3783392 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,38071603 0,38513013 ! nucleosome assembly GO:0006334 126 87 0,000 0,38071603 0,38497073 ! cellular respiration GO:0045333 143 88 0,000 0,38412186 0,38825391 ! amine biosynthetic process GO:0009309 146 88 0,000 0,38412186 0,38809334 ! sensory perception of smell GO:0007608 117 88 0,000 0,38412186 0,38793291 ! chromatin assembly GO:0031497 128 88 0,000 0,38412186 0,38777261 ! tube morphogenesis GO:0035239 194 89 0,000 0,38750905 0,39103041 ! cellular defense response GO:0006968 123 89 0,000 0,38750905 0,39086896 ! response to inorganic substance GO:0010035 173 90 0,000 0,39087771 0,3941041 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,39087771 0,39394152 ! response to unfolded protein GO:0006986 139 90 0,000 0,39087771 0,39377907 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,39087771 0,39361675 ! gland development GO:0048732 220 91 0,000 0,39422793 0,39682688 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,39755982 0,40001592 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,40087348 0,40318399 ! amine transport GO:0015837 181 93 0,000 0,40087348 0,40301807 ! vitamin metabolic process GO:0006766 153 93 0,000 0,40087348 0,40285229 ! female pregnancy GO:0007565 166 94 0,000 0,40416901 0,40599708 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,40416901 0,4058302 ! regulation of defense response GO:0031347 171 95 0,000 0,4074465 0,40895308 ! nucleosome organization GO:0034728 143 95 0,000 0,4074465 0,40878513 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,4074465 0,40861732 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,4074465 0,40844965 ! sex differentiation GO:0007548 171 96 0,000 0,41070605 0,41154835 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,41394777 0,41462665 ! leukocyte differentiation GO:0002521 232 98 0,000 0,41717174 0,41768466 ! forebrain development GO:0030900 210 98 0,000 0,41717174 0,41751355 ! mRNA transport GO:0051028 185 100 0,000 0,42356685 0,4237403 ! hormone metabolic process GO:0042445 171 100 0,000 0,42356685 0,42356685