pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/596-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 9,871E-07 2,411E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 1,804E-06 2,204E-03 ! isoprenoid biosynthetic process GO:0008299 34 16 2,000 4,566E-06 3,718E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 5,955E-06 3,637E-03 ! cholesterol biosynthetic process GO:0006695 39 22 2,000 1,244E-05 6,08E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,279E-05 5,209E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,355E-05 4,728E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,69E-05 5,159E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 1,85E-05 5,023E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 3,000 2,417E-05 5,904E-03 ! sterol biosynthetic process GO:0016126 56 30 2,000 3,242E-05 7,201E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 3,242E-05 6,601E-03 ! B cell homeostasis GO:0001782 13 5 1,000 4,144E-05 7,787E-03 ! regulation of ARF GTPase activity GO:0032312 73 34 2,000 4,751E-05 8,29E-03 ! transcription initiation GO:0006352 171 97 3,000 4,91E-05 7,996E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 6,207E-05 9,478E-03 ! neuron apoptosis GO:0051402 15 6 1,000 6,207E-05 8,92E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 6,207E-05 8,425E-03 ! isoprenoid metabolic process GO:0006720 70 39 2,000 7,202E-05 9,261E-03 ! induction of apoptosis by oxidative stress GO:0008631 9 7 1,000 8,679E-05 0,01060119 ! coenzyme A metabolic process GO:0015936 12 7 1,000 8,679E-05 0,01009638 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 1,108E-04 0,01230873 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 1,156E-04 0,01227488 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,431E-04 0,01456353 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,484E-04 0,01450011 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,484E-04 0,01394242 ! regulation of activated T cell proliferation GO:0046006 19 9 1,000 1,484E-04 0,01342603 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,52E-04 0,01326027 ! regulation of ARF protein signal transduction GO:0032012 115 50 2,000 1,52E-04 0,01280302 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 2,000 1,709E-04 0,01391381 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 1,808E-04 0,01425187 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,852E-04 0,01414143 ! response to UV GO:0009411 120 55 2,000 2,019E-04 0,01494939 ! RNA elongation GO:0006354 90 56 2,000 2,131E-04 0,01530845 ! germ cell migration GO:0008354 26 11 1,000 2,261E-04 0,01578146 ! DNA catabolic process GO:0006308 94 60 2,000 2,615E-04 0,01774342 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 2,71E-04 0,01789027 ! T cell homeostasis GO:0043029 28 12 1,000 2,71E-04 0,01741947 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 2,71E-04 0,01697282 GO:0042130|negative regulation of T cell proliferation, ! response to peptide hormone stimulus GO:0043434 129 64 2,000 3,165E-04 0,01932878 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 3,726E-04 0,0222012 ! lymphocyte homeostasis GO:0002260 33 15 1,000 4,293E-04 0,0249736 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,9E-04 0,02784045 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 4,9E-04 0,02720771 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 5,546E-04 0,03011011 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 5,546E-04 0,02945554 ! steroid biosynthetic process GO:0006694 146 79 2,000 5,876E-04 0,0305413 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 6,955E-04 0,03539858 ! visual learning GO:0008542 38 19 1,000 6,955E-04 0,03467616 ! cholesterol metabolic process GO:0008203 148 85 2,000 7,274E-04 0,03554273 ! negative regulation of T cell activation GO:0050868 41 20 1,000 7,718E-04 0,03696895 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 7,718E-04 0,03625801 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 7,718E-04 0,03557389 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 7,718E-04 0,03491512 ! lipid phosphorylation GO:0046834 43 21 1,000 8,519E-04 0,03783843 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 8,519E-04 0,03716274 ! apoptotic nuclear changes GO:0030262 34 22 1,000 9,358E-04 0,0401085 ! G1 phase GO:0051318 44 22 1,000 9,358E-04 0,03941697 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 9,358E-04 0,03874889 ! positive regulation of B cell activation GO:0050871 42 22 1,000 9,358E-04 0,03810307 ! sterol metabolic process GO:0016125 166 94 2,000 9,743E-04 0,03901882 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 1,000 1,024E-03 0,04033212 ! visual behavior GO:0007632 46 23 1,000 1,024E-03 0,03969193 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 1,024E-03 0,03907174 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 1,099E-03 0,04130585 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 1,115E-03 0,04127722 ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 1,115E-03 0,04066114 GO:0042278|purine nucleoside metabolic process, ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,115E-03 0,04006318 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 1,211E-03 0,04285885 ! leukocyte homeostasis GO:0001776 50 25 1,000 1,211E-03 0,04224658 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 1,31E-03 0,04506263 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 1,31E-03 0,04443676 GO:0045936|negative regulation of phosphate metabolic process, ! insulin receptor signaling pathway GO:0008286 66 27 1,000 1,413E-03 0,04727147 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 1,413E-03 0,04663266 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 1,519E-03 0,04948444 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 1,519E-03 0,04883333 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 1,63E-03 0,05170076 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 1,861E-03 0,0582998 ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 1,861E-03 0,05756183 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 1,983E-03 0,06055139 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 2,237E-03 0,0674618 ! androgen receptor signaling pathway GO:0030521 81 37 1,000 2,645E-03 0,07879753 ! negative regulation of cell activation GO:0050866 69 37 1,000 2,645E-03 0,07784816 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 2,788E-03 0,08108723 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 2,935E-03 0,0843529 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 82 40 1,000 3,085E-03 0,08764381 ! nucleus organization GO:0006997 73 40 1,000 3,085E-03 0,08663641 ! Rho protein signal transduction GO:0007266 88 40 1,000 3,085E-03 0,08565191 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 3,397E-03 0,09323678 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 3,397E-03 0,09220082 ! regulation of T cell proliferation GO:0042129 80 43 1,000 3,558E-03 0,09550918 ! keratinocyte differentiation GO:0030216 81 45 1,000 3,89E-03 0,1032989 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 4,062E-03 0,10669169 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 4,062E-03 0,10555668 ! cell growth GO:0016049 90 46 1,000 4,062E-03 0,10444555 ! positive regulation of protein transport GO:0051222 80 46 1,000 4,062E-03 0,10335758 ! response to insulin stimulus GO:0032868 98 47 1,000 4,236E-03 0,10669699 ! cellular component disassembly GO:0022411 89 48 1,000 4,415E-03 0,11005412 ! positive regulation of DNA binding GO:0043388 83 48 1,000 4,415E-03 0,10894246 ! protein homooligomerization GO:0051260 84 49 1,000 4,597E-03 0,11229379 ! epidermal cell differentiation GO:0009913 87 50 1,000 4,782E-03 0,11566138 ! negative regulation of immune system process GO:0002683 101 51 1,000 4,97E-03 0,11904441 ! positive regulation of binding GO:0051099 88 52 1,000 5,162E-03 0,12244208 ! Notch signaling pathway GO:0007219 111 52 1,000 5,162E-03 0,12126475 ! regulation of DNA replication GO:0006275 105 56 1,000 5,964E-03 0,1387581 ! nucleotide-excision repair GO:0006289 91 57 1,000 6,173E-03 0,14225901 ! regulation of intracellular transport GO:0032386 108 57 1,000 6,173E-03 0,14092948 ! lipid modification GO:0030258 112 60 1,000 6,818E-03 0,15423407 ! nucleoside metabolic process GO:0009116 91 62 1,000 7,265E-03 0,1628352 ! gonad development GO:0008406 115 66 1,000 8,198E-03 0,1820639 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 8,198E-03 0,18042368 ! negative regulation of cell growth GO:0030308 142 67 1,000 8,439E-03 0,18407154 ! negative regulation of cell size GO:0045792 144 69 1,000 8,93E-03 0,19307194 ! homeostasis of number of cells GO:0048872 131 69 1,000 8,93E-03 0,19137833 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 9,435E-03 0,20042513 ! regulation of caspase activity GO:0043281 136 74 1,000 0,01021425 0,21511559 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01022744 0,21355247 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01022744 0,21174271 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01022744 0,20996336 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01022744 0,20821366 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01022744 0,20649289 ! neuron fate determination GO:0048664 7 5 0,000 0,01022744 0,20480032 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01022744 0,20313528 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01022744 0,20149709 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01022744 0,19988512 ! polyol transport GO:0015791 12 5 0,000 0,01022744 0,19829873 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01022744 0,19673732 ! response to superoxide GO:0000303 10 5 0,000 0,01022744 0,19520031 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01022744 0,19368713 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01022744 0,19219723 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01022744 0,19073007 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01022744 0,18928515 ! female meiosis GO:0007143 10 5 0,000 0,01022744 0,18786195 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01022744 0,18646 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01022744 0,18507881 ! hypothalamus development GO:0021854 9 5 0,000 0,01022744 0,18371794 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01022744 0,18237693 ! cobalt ion transport GO:0006824 11 5 0,000 0,01022744 0,18105536 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01022744 0,1797528 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01022744 0,17846885 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01022744 0,17720312 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01022744 0,17595521 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01022744 0,17472475 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01022744 0,17351139 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01022744 0,17231475 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01022744 0,17113452 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01022744 0,16997034 ! transposition GO:0032196 9 5 0,000 0,01022744 0,16882189 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01022744 0,16768886 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01022744 0,16657093 ! negative chemotaxis GO:0050919 16 5 0,000 0,01022744 0,16546781 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01022744 0,16437921 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01022744 0,16330483 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01022744 0,16224441 ! behavioral response to pain GO:0048266 10 5 0,000 0,01022744 0,16119767 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01022744 0,16016436 ! Notch receptor processing GO:0007220 11 5 0,000 0,01022744 0,1591442 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01022744 0,15813696 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01022744 0,15714239 ! micturition GO:0060073 9 5 0,000 0,01022744 0,15616025 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01022744 0,15519031 ! copulation GO:0007620 9 5 0,000 0,01022744 0,15423234 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01022744 0,15328613 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01022744 0,15235146 ! bioluminescence GO:0008218 9 5 0,000 0,01022744 0,15142812 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01022744 0,1505159 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01022744 0,14961461 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01022744 0,14872404 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01022744 0,14784402 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01022744 0,14697435 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01022744 0,14611485 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01022744 0,14526535 ! grooming behavior GO:0007625 6 5 0,000 0,01022744 0,14442566 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01022744 0,14359563 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01022744 0,14277508 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01022744 0,14196386 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01022744 0,1411618 ! response to protozoan GO:0001562 13 5 0,000 0,01022744 0,14036876 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,01022744 0,13958458 ! lymph vessel development GO:0001945 10 5 0,000 0,01022744 0,13880911 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01022744 0,13804221 ! endochondral ossification GO:0001958 17 5 0,000 0,01022744 0,13728373 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01022744 0,13653355 ! single strand break repair GO:0000012 8 5 0,000 0,01022744 0,13579152 ! parathyroid gland development GO:0060017 14 5 0,000 0,01022744 0,13505751 ! anagen GO:0042640 7 5 0,000 0,01022744 0,13433139 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01022744 0,13361305 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01022744 0,13290234 ! cytokine secretion GO:0050663 15 5 0,000 0,01022744 0,13219915 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01022744 0,13150337 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01022744 0,13081487 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01022744 0,13013354 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01022744 0,12945927 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01022744 0,12879196 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01022744 0,12813148 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01022744 0,12747775 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01022744 0,12683066 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01022744 0,1261901 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01022744 0,12555598 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01022744 0,1249282 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01022744 0,12430666 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01022744 0,12369128 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01022744 0,12308197 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01022744 0,12247862 ! microvillus organization GO:0032528 8 5 0,000 0,01022744 0,12188117 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01022744 0,12128951 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01022744 0,12070357 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01022744 0,12012327 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01022744 0,11954851 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01022744 0,11897924 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01022744 0,11841535 ! polyol catabolic process GO:0046174 9 5 0,000 0,01022744 0,11785679 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01022744 0,11730347 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01022744 0,11675532 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01022744 0,11621228 ! muscle cell migration GO:0014812 8 5 0,000 0,01022744 0,11567426 ! mitochondrial fission GO:0000266 8 5 0,000 0,01022744 0,1151412 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01022744 0,11461303 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01022744 0,11408968 ! mRNA transcription GO:0009299 10 5 0,000 0,01022744 0,11357109 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01022744 0,11305719 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01022744 0,11254793 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01022744 0,11204323 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01022744 0,11154303 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01022744 0,11104729 ! monocyte activation GO:0042117 10 5 0,000 0,01022744 0,11055593 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01022744 0,1100689 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01022744 0,10958614 ! response to food GO:0032094 6 5 0,000 0,01022744 0,1091076 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01022744 0,10863322 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01022744 0,10816294 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01022744 0,10769672 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01022744 0,1072345 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01022744 0,10677624 ! forebrain neuron development GO:0021884 13 5 0,000 0,01022744 0,10632187 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01022744 0,10587135 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01022744 0,10542464 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01022744 0,10498168 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01022744 0,10454242 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01022744 0,10410683 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01022744 0,10367485 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01022744 0,10324644 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01022744 0,10282156 ! lipid glycosylation GO:0030259 7 5 0,000 0,01022744 0,10240016 ! nucleobase transport GO:0015851 6 5 0,000 0,01022744 0,1019822 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01022744 0,10156764 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01022744 0,10115644 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01022744 0,10074855 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01022744 0,10034393 ! basic amino acid transport GO:0015802 12 5 0,000 0,01022744 0,09994256 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01022744 0,09954438 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01022744 0,09914936 ! actin nucleation GO:0045010 11 5 0,000 0,01022744 0,09875747 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01022744 0,09836866 ! depurination GO:0045007 5 5 0,000 0,01022744 0,0979829 ! depyrimidination GO:0045008 10 5 0,000 0,01022744 0,09760015 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01022744 0,09722039 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01022744 0,09684356 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01022744 0,09646965 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01022744 0,09609861 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01022744 0,09573042 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01022744 0,09536504 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01022744 0,09500243 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01022744 0,09464257 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01022744 0,09428543 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01022744 0,09393098 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01022744 0,09357917 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01022744 0,09323 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01022744 0,09288342 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01022744 0,09253941 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01022744 0,09219793 ! response to arsenic GO:0046685 11 5 0,000 0,01022744 0,09185897 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01022744 0,09152249 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01022744 0,09118847 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01022744 0,09085687 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01022744 0,09052768 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01022744 0,09020086 ! response to mercury ion GO:0046689 8 5 0,000 0,01022744 0,0898764 ! response to cadmium ion GO:0046686 7 5 0,000 0,01022744 0,08955426 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01022744 0,08923443 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01022744 0,08891687 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01022744 0,08860156 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01022744 0,08828848 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01022744 0,0879776 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01022744 0,08766891 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01022744 0,08736238 ! decidualization GO:0046697 11 5 0,000 0,01022744 0,08705798 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01022744 0,08675569 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01022744 0,0864555 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01022744 0,08615738 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01022744 0,0858613 ! embryonic cleavage GO:0040016 6 5 0,000 0,01022744 0,08556726 ! peroxisome fission GO:0016559 5 5 0,000 0,01022744 0,08527522 ! histone demethylation GO:0016577 13 5 0,000 0,01022744 0,08498517 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01022744 0,08469708 ! mitotic recombination GO:0006312 9 5 0,000 0,01022744 0,08441094 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01022744 0,08412673 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01022744 0,08384443 ! metaphase plate congression GO:0051310 7 5 0,000 0,01022744 0,08356401 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01022744 0,08328546 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01022744 0,08300877 ! enteric nervous system development GO:0048484 8 5 0,000 0,01022744 0,08273391 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01022744 0,08246086 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01022744 0,0821896 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01022744 0,08192013 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01022744 0,08165242 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01022744 0,08138645 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01022744 0,08112221 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01022744 0,08085967 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01022744 0,08059884 ! metaphase GO:0051323 11 5 0,000 0,01022744 0,08033968 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01022744 0,08008218 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01022744 0,07982632 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01022744 0,0795721 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01022744 0,07931949 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01022744 0,07906848 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01022744 0,07881905 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01022744 0,07857119 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01022744 0,07832489 ! response to redox state GO:0051775 6 5 0,000 0,01022744 0,07808012 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01022744 0,07783688 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01022744 0,07759515 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01022744 0,07735492 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01022744 0,07711617 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01022744 0,07687889 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01022744 0,07664307 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01022744 0,07640868 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01022744 0,07617573 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01022744 0,07594419 ! striatum development GO:0021756 14 5 0,000 0,01022744 0,07571406 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01022744 0,07548532 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01022744 0,07525795 ! glial cell migration GO:0008347 10 5 0,000 0,01022744 0,07503195 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01022744 0,0748073 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01022744 0,074584 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01022744 0,07436202 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01022744 0,07414136 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01022744 0,07392201 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01022744 0,07370395 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01022744 0,07348717 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01022744 0,07327167 ! neuroprotection GO:0043526 8 5 0,000 0,01022744 0,07305743 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01022744 0,07284443 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01022744 0,07263267 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01022744 0,07242214 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01022744 0,07221283 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01022744 0,07200472 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01022744 0,07179781 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01022744 0,07159209 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01022744 0,07138754 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01022744 0,07118416 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01022744 0,07098193 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01022744 0,07078085 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01022744 0,0705809 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01022744 0,07038208 ! spindle assembly GO:0051225 6 5 0,000 0,01022744 0,07018438 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01022744 0,06998779 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01022744 0,06979229 ! protein palmitoylation GO:0018345 12 5 0,000 0,01022744 0,06959788 ! drug metabolic process GO:0017144 7 5 0,000 0,01022744 0,06940455 ! stem cell division GO:0017145 11 5 0,000 0,01022744 0,0692123 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01022744 0,0690211 ! organ regeneration GO:0031100 7 5 0,000 0,01022744 0,06883096 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01022744 0,06864187 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01022744 0,06845381 ! reproductive structure development GO:0048608 131 75 1,000 0,01048026 0,06995433 ! learning or memory GO:0007611 161 76 1,000 0,01074933 0,07155483 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01102145 0,07316683 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,01102145 0,07296855 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01129659 0,07458801 ! protein oligomerization GO:0051259 149 79 1,000 0,01157474 0,0762186 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0118559 0,07786013 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01226051 0,08030144 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01226051 0,08008673 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01226051 0,07987317 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01226051 0,07966074 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01226051 0,07944944 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01226051 0,07923925 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01226051 0,07903018 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01226051 0,0788222 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01226051 0,07861532 ! response to oxygen radical GO:0000305 11 6 0,000 0,01226051 0,07840952 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01226051 0,0782048 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01226051 0,07800114 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01226051 0,07779854 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01226051 0,07759699 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01226051 0,07739648 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01226051 0,077197 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01226051 0,07699855 ! forebrain regionalization GO:0021871 9 6 0,000 0,01226051 0,07680112 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01226051 0,0766047 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01226051 0,07640928 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01226051 0,07621485 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01226051 0,07602142 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01226051 0,07582896 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01226051 0,07563747 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01226051 0,07544695 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01226051 0,07525738 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01226051 0,07506877 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01226051 0,07488109 ! malate metabolic process GO:0006108 13 6 0,000 0,01226051 0,07469436 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01226051 0,07450855 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01226051 0,07432367 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01226051 0,0741397 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01226051 0,07395664 ! protein refolding GO:0042026 15 6 0,000 0,01226051 0,07377448 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01226051 0,07359321 ! opsonization GO:0008228 8 6 0,000 0,01226051 0,07341284 ! mating behavior GO:0007617 7 6 0,000 0,01226051 0,07323334 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01226051 0,07305473 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01226051 0,07287698 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01226051 0,07270009 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01226051 0,07252406 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01226051 0,07234888 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01226051 0,07217455 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01226051 0,07200105 ! toxin metabolic process GO:0009404 11 6 0,000 0,01226051 0,07182839 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01226051 0,07165655 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01226051 0,07148553 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01226051 0,07131533 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,01226051 0,07114593 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01226051 0,07097734 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01226051 0,07080955 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01226051 0,07064254 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01226051 0,07047632 ! thymic T cell selection GO:0045061 16 6 0,000 0,01226051 0,07031089 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01226051 0,07014622 ! protein lipoylation GO:0009249 10 6 0,000 0,01226051 0,06998233 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01226051 0,0698192 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01226051 0,06965683 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01226051 0,06949522 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01226051 0,06933435 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01226051 0,06917422 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01226051 0,06901483 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01226051 0,06885618 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01226051 0,06869825 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01226051 0,06854105 ! hyperosmotic response GO:0006972 10 6 0,000 0,01226051 0,06838456 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01226051 0,06822879 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01226051 0,06807372 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01226051 0,06791936 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01226051 0,0677657 ! urea metabolic process GO:0019627 7 6 0,000 0,01226051 0,06761273 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01226051 0,06746045 ! neutrophil activation GO:0042119 7 6 0,000 0,01226051 0,06730885 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01226051 0,06715793 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01226051 0,06700769 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01226051 0,06685812 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01226051 0,06670922 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01226051 0,06656097 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01226051 0,06641339 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01226051 0,06626646 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01226051 0,06612017 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01226051 0,06597453 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01226051 0,06582953 ! carnitine transport GO:0015879 10 6 0,000 0,01226051 0,06568517 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01226051 0,06554144 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01226051 0,06539834 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01226051 0,06525586 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01226051 0,065114 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01226051 0,06497275 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01226051 0,06483212 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01226051 0,06469209 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01226051 0,06455267 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01226051 0,06441384 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01226051 0,06427562 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01226051 0,06413798 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01226051 0,06400094 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01226051 0,06386447 ! response to UV-C GO:0010225 14 6 0,000 0,01226051 0,06372859 ! astrocyte development GO:0014002 16 6 0,000 0,01226051 0,06359329 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01226051 0,06345855 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01226051 0,06332439 ! interaction with symbiont GO:0051702 14 6 0,000 0,01226051 0,0631908 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01226051 0,06305776 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01226051 0,06292529 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01226051 0,06279337 ! response to copper ion GO:0046688 10 6 0,000 0,01226051 0,062662 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01226051 0,06253119 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01226051 0,06240091 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01226051 0,06227118 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01226051 0,06214199 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01226051 0,06201333 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01226051 0,0618852 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01226051 0,0617576 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01226051 0,06163053 ! hair follicle maturation GO:0048820 8 6 0,000 0,01226051 0,06150398 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01226051 0,06137795 ! Schwann cell development GO:0014044 15 6 0,000 0,01226051 0,06125243 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01226051 0,06112742 ! response to pheromone GO:0019236 6 6 0,000 0,01226051 0,06100293 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01226051 0,06087894 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01226051 0,06075545 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01226051 0,06063247 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01226051 0,06050998 ! subpallium development GO:0021544 15 6 0,000 0,01226051 0,06038798 ! neural tube patterning GO:0021532 8 6 0,000 0,01226051 0,06026647 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01226051 0,06014546 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01226051 0,06002493 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01226051 0,05990488 ! G2 phase GO:0051319 16 6 0,000 0,01226051 0,05978531 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01226051 0,05966621 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01226051 0,05954759 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01226051 0,05942944 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01226051 0,05931176 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01226051 0,05919454 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01226051 0,05907779 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01226051 0,05896149 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01226051 0,05884565 ! receptor internalization GO:0031623 11 6 0,000 0,01226051 0,05873027 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01226051 0,05861534 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01226051 0,05850086 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01226051 0,05838682 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01226051 0,05827323 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01226051 0,05816007 ! protein deubiquitination GO:0016579 16 6 0,000 0,01226051 0,05804736 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01226051 0,05793508 ! protein destabilization GO:0031648 9 6 0,000 0,01226051 0,05782324 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01226051 0,05771183 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01226051 0,05760084 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01226051 0,05749028 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01226051 0,05738015 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01226051 0,05727044 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01226051 0,05716114 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01226051 0,05705226 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01226051 0,0569438 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01226051 0,05683575 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01226051 0,0567281 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01226051 0,05662087 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01226051 0,05651403 ! neural plate development GO:0001840 9 6 0,000 0,01226051 0,0564076 ! catecholamine transport GO:0051937 9 6 0,000 0,01226051 0,05630157 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01226051 0,05619594 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01226051 0,05609071 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01226051 0,05598587 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01226051 0,05588141 ! maternal placenta development GO:0001893 12 6 0,000 0,01226051 0,05577735 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01226051 0,05567368 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01226051 0,05557039 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01226051 0,05546748 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01226051 0,05536495 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01226051 0,0552628 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01226051 0,05516103 GO:0055081|anion homeostasis, ! regulation of peptidase activity GO:0052547 150 82 1,000 0,01242717 0,05580806 ! response to drug GO:0042493 149 83 1,000 0,01271726 0,05700599 ! response to nutrient GO:0007584 135 84 1,000 0,01301029 0,05821273 ! negative regulation of growth GO:0045926 168 85 1,000 0,01330627 0,05942817 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,01330627 0,05931973 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,01360516 0,06054174 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 0,01390697 0,06177223 ! regulation of protein transport GO:0051223 165 87 1,000 0,01390697 0,06166012 GO:0070201|regulation of establishment of protein localization, ! tRNA transcription GO:0009304 17 7 0,000 0,01428947 0,06324126 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01428947 0,0631269 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01428947 0,06301295 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01428947 0,06289941 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01428947 0,06278628 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01428947 0,06267356 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01428947 0,06256124 ! sleep GO:0030431 16 7 0,000 0,01428947 0,06244933 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01428947 0,06233781 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01428947 0,06222669 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01428947 0,06211597 ! prostate gland development GO:0030850 14 7 0,000 0,01428947 0,06200564 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01428947 0,0618957 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01428947 0,06178615 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01428947 0,06167699 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01428947 0,06156821 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01428947 0,06145981 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01428947 0,0613518 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01428947 0,06124416 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01428947 0,06113691 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01428947 0,06103002 ! glycolipid transport GO:0046836 11 7 0,000 0,01428947 0,06092351 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01428947 0,06081738 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01428947 0,06071161 ! neuron adhesion GO:0007158 14 7 0,000 0,01428947 0,0606062 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01428947 0,06050117 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01428947 0,06039649 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01428947 0,06029218 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01428947 0,06018823 ! mRNA stabilization GO:0048255 18 7 0,000 0,01428947 0,06008464 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01428947 0,0599814 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01428947 0,05987851 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01428947 0,05977598 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01428947 0,0596738 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01428947 0,05957197 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01428947 0,05947048 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01428947 0,05936934 ! lipoprotein transport GO:0042953 14 7 0,000 0,01428947 0,05926855 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01428947 0,05916809 ! rhythmic behavior GO:0007622 17 7 0,000 0,01428947 0,05906798 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01428947 0,0589682 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01428947 0,05886876 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01428947 0,05876965 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01428947 0,05867088 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01428947 0,05857244 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01428947 0,05847433 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01428947 0,05837654 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01428947 0,05827909 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01428947 0,05818196 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01428947 0,05808515 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01428947 0,05798866 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01428947 0,05789249 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01428947 0,05779664 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01428947 0,05770111 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01428947 0,0576059 ! spinal cord patterning GO:0021511 14 7 0,000 0,01428947 0,05751099 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01428947 0,0574164 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01428947 0,05732212 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01428947 0,05722815 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01428947 0,05713449 ! adrenal gland development GO:0030325 17 7 0,000 0,01428947 0,05704113 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01428947 0,05694808 ! ovulation GO:0030728 10 7 0,000 0,01428947 0,05685533 ! adenohypophysis development GO:0021984 11 7 0,000 0,01428947 0,05676288 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01428947 0,05667074 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01428947 0,05657889 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01428947 0,05648734 ! microtubule nucleation GO:0007020 21 7 0,000 0,01428947 0,05639608 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01428947 0,05630512 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01428947 0,05621445 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01428947 0,05612407 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01428947 0,05603399 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01428947 0,05594419 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01428947 0,05585468 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01428947 0,05576545 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01428947 0,05567651 ! galactose metabolic process GO:0006012 13 7 0,000 0,01428947 0,05558786 ! vesicle fusion GO:0006906 20 7 0,000 0,01428947 0,05549948 ! response to dietary excess GO:0002021 8 7 0,000 0,01428947 0,05541139 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01428947 0,05532357 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01428947 0,05523603 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01428947 0,05514877 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01428947 0,05506179 ! organ growth GO:0035265 15 7 0,000 0,01428947 0,05497508 ! nucleoside transport GO:0015858 11 7 0,000 0,01428947 0,05488864 ! nucleoside salvage GO:0043174 11 7 0,000 0,01428947 0,05480247 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01428947 0,05471657 ! male sex determination GO:0030238 15 7 0,000 0,01428947 0,05463094 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01428947 0,05454558 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01428947 0,05446049 ! parturition GO:0007567 16 7 0,000 0,01428947 0,05437566 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01428947 0,05429109 ! rRNA modification GO:0000154 14 7 0,000 0,01428947 0,05420679 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01428947 0,05412275 ! spindle checkpoint GO:0031577 16 7 0,000 0,01428947 0,05403897 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01428947 0,05395545 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01428947 0,05387218 ! monocyte differentiation GO:0030224 16 7 0,000 0,01428947 0,05378917 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01428947 0,05370642 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01428947 0,05362392 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01428947 0,05354168 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01428947 0,05345968 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01428947 0,05337794 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01428947 0,05329645 ! fibrinolysis GO:0042730 11 7 0,000 0,01428947 0,0532152 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01428947 0,05313421 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01428947 0,05305346 ! eating behavior GO:0042755 8 7 0,000 0,01428947 0,05297295 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01428947 0,05289269 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01428947 0,05281267 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01428947 0,05273289 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01428947 0,05265335 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01428947 0,05257406 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01428947 0,052495 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01428947 0,05241618 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01428947 0,05233759 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01428947 0,05225924 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01428947 0,05218113 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01428947 0,05210324 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01428947 0,05202559 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01428947 0,05194817 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01428947 0,05187099 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01428947 0,05179403 ! histone ubiquitination GO:0016574 9 7 0,000 0,01428947 0,05171729 ! regulation of meiosis GO:0040020 12 7 0,000 0,01428947 0,05164079 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01428947 0,05156451 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01428947 0,05148846 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01428947 0,05141263 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01428947 0,05133702 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01428947 0,05126164 ! transcription termination GO:0006353 14 7 0,000 0,01428947 0,05118647 ! anaphase GO:0051322 18 7 0,000 0,01428947 0,05111153 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01428947 0,0510368 ! axonal fasciculation GO:0007413 19 7 0,000 0,01428947 0,0509623 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01428947 0,05088801 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01428947 0,05081394 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01428947 0,05074008 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01428947 0,05066643 ! diuresis GO:0030146 12 7 0,000 0,01428947 0,05059301 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01428947 0,05051979 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01428947 0,05044678 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01428947 0,05037399 ! antibiotic transport GO:0042891 9 7 0,000 0,01428947 0,0503014 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01428947 0,05022903 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01428947 0,05015686 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01428947 0,0500849 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01428947 0,05001314 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01428947 0,04994159 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01428947 0,04987025 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01428947 0,04979911 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01428947 0,04972817 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01428947 0,04965743 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01428947 0,04958689 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01428947 0,04951656 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01428947 0,04944642 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01428947 0,04937648 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01428947 0,04930674 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01428947 0,0492372 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01428947 0,04916785 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01428947 0,0490987 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01428947 0,04902974 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01428947 0,04896097 ! muscle adaptation GO:0043500 13 7 0,000 0,01428947 0,0488924 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01428947 0,04882402 ! retina homeostasis GO:0001895 12 7 0,000 0,01428947 0,04875583 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01428947 0,04868783 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01428947 0,04862002 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01428947 0,0485524 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01428947 0,04848496 ! regulation of DNA binding GO:0051101 167 89 1,000 0,01451927 0,04919635 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,01631431 0,05520203 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,01631431 0,05512568 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,01631431 0,05504954 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,01631431 0,05497361 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,01631431 0,05489789 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,01631431 0,05482237 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,01631431 0,05474707 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,01631431 0,05467197 ! male meiosis GO:0007140 9 8 0,000 0,01631431 0,05459708 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,01631431 0,05452239 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,01631431 0,05444791 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,01631431 0,05437362 ! meiotic prophase I GO:0007128 14 8 0,000 0,01631431 0,05429955 ! response to zinc ion GO:0010043 12 8 0,000 0,01631431 0,05422567 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,01631431 0,05415199 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,01631431 0,05407852 ! oligopeptide transport GO:0006857 16 8 0,000 0,01631431 0,05400524 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,01631431 0,05393216 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,01631431 0,05385928 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,01631431 0,05378659 ! signal peptide processing GO:0006465 12 8 0,000 0,01631431 0,05371411 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,01631431 0,05364181 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,01631431 0,05356971 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,01631431 0,05349781 ! succinate metabolic process GO:0006105 17 8 0,000 0,01631431 0,05342609 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,01631431 0,05335457 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,01631431 0,05328324 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,01631431 0,0532121 ! estrogen metabolic process GO:0008210 17 8 0,000 0,01631431 0,05314116 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,01631431 0,05307039 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,01631431 0,05299982 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,01631431 0,05292944 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,01631431 0,05285924 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,01631431 0,05278923 ! reflex GO:0060004 17 8 0,000 0,01631431 0,0527194 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,01631431 0,05264976 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,01631431 0,0525803 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,01631431 0,05251102 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,01631431 0,05244193 ! pigment granule organization GO:0048753 17 8 0,000 0,01631431 0,05237302 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,01631431 0,05230429 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,01631431 0,05223574 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,01631431 0,05216736 ! astrocyte differentiation GO:0048708 19 8 0,000 0,01631431 0,05209917 ! histidine catabolic process GO:0006548 10 8 0,000 0,01631431 0,05203116 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,01631431 0,05196332 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,01631431 0,05189566 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,01631431 0,05182817 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,01631431 0,05176087 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,01631431 0,05169373 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,01631431 0,05162677 ! melanin metabolic process GO:0006582 17 8 0,000 0,01631431 0,05155998 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,01631431 0,05149337 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,01631431 0,05142692 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,01631431 0,05136065 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,01631431 0,05129455 ! macrophage activation GO:0042116 13 8 0,000 0,01631431 0,05122862 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,01631431 0,05116286 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,01631431 0,05109726 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,01631431 0,05103184 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,01631431 0,05096658 ! purine salvage GO:0043101 12 8 0,000 0,01631431 0,05090149 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,01631431 0,05083656 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,01631431 0,0507718 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,01631431 0,05070721 ! osteoblast development GO:0002076 17 8 0,000 0,01631431 0,05064278 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,01631431 0,05057851 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,01631431 0,05051441 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,01631431 0,05045046 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,01631431 0,05038668 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,01631431 0,05032306 ! response to UV-B GO:0010224 17 8 0,000 0,01631431 0,0502596 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,01631431 0,05019631 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,01631431 0,05013317 ! intermediate filament organization GO:0045109 12 8 0,000 0,01631431 0,05007018 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,01631431 0,05000736 ! cellular extravasation GO:0045123 13 8 0,000 0,01631431 0,04994469 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,01631431 0,04988219 ! response to antibiotic GO:0046677 11 8 0,000 0,01631431 0,04981983 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,01631431 0,04975764 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,01631431 0,04969559 ! DNA topological change GO:0006265 12 8 0,000 0,01631431 0,04963371 ! response to tropane GO:0014073 15 8 0,000 0,01631431 0,04957197 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,01631431 0,04951039 ! melanosome transport GO:0032402 13 8 0,000 0,01631431 0,04944897 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,01631431 0,04938769 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,01631431 0,04932657 ! mast cell activation GO:0045576 14 8 0,000 0,01631431 0,0492656 ! multicellular organismal aging GO:0010259 20 8 0,000 0,01631431 0,04920477 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,01631431 0,0491441 ! gas homeostasis GO:0033483 14 8 0,000 0,01631431 0,04908358 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,01631431 0,04902321 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,01631431 0,04896298 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,01631431 0,0489029 ! nucleosome disassembly GO:0006337 14 8 0,000 0,01631431 0,04884297 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,01631431 0,04878319 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,01631431 0,04872355 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,01631431 0,04866406 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,01631431 0,04860472 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,01631431 0,04854551 ! intracellular lipid transport GO:0032365 16 8 0,000 0,01631431 0,04848646 ! response to tumor cell GO:0002347 16 8 0,000 0,01631431 0,04842754 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,01631431 0,04836877 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,01631431 0,04831014 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,01631431 0,04825165 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,01631431 0,04819331 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,01631431 0,0481351 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,01631431 0,04807704 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,01631431 0,04801912 ! hormone catabolic process GO:0042447 17 8 0,000 0,01631431 0,04796133 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,01631431 0,04790369 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,01631431 0,04784618 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,01631431 0,04778881 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,01631431 0,04773158 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,01631431 0,04767448 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,01631431 0,04761752 ! adult feeding behavior GO:0008343 10 8 0,000 0,01631431 0,0475607 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,01631431 0,04750401 ! ATP catabolic process GO:0006200 11 8 0,000 0,01631431 0,04744746 ! blastocyst growth GO:0001832 19 8 0,000 0,01631431 0,04739104 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,01631431 0,04733476 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,01631431 0,04727861 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,01631431 0,04722259 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,01631431 0,04716671 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,01631431 0,04711095 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,01631431 0,04705533 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,01631431 0,04699984 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,01631431 0,04694448 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,01631431 0,04688925 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,01631431 0,04683416 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,01631431 0,04677919 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,01631431 0,04672435 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,01631431 0,04666963 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,01631431 0,04661505 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,01631431 0,04656059 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,01631431 0,04650626 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,01631431 0,04645206 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,01631431 0,04639798 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,01631431 0,04634403 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,01631431 0,04629021 ! sex differentiation GO:0007548 171 96 1,000 0,01675211 0,04747727 ! regulation of T cell activation GO:0050863 175 96 1,000 0,01675211 0,04742226 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,01708233 0,04830107 ! regulation of protein localization GO:0032880 188 97 1,000 0,01708233 0,04824523 ! axon extension GO:0048675 16 9 0,000 0,01833505 0,05172348 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,01833505 0,05166383 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,01833505 0,05160431 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,01833505 0,05154492 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,01833505 0,05148567 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,01833505 0,05142656 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,01833505 0,05136759 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,01833505 0,05130875 ! reproductive behavior GO:0019098 22 9 0,000 0,01833505 0,05125004 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,01833505 0,05119147 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,01833505 0,05113303 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,01833505 0,05107473 ! UTP metabolic process GO:0046051 10 9 0,000 0,01833505 0,05101656 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,01833505 0,05095852 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,01833505 0,05090061 ! artery development GO:0060840 25 9 0,000 0,01833505 0,05084283 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,01833505 0,05078519 ! regulation of glycolysis GO:0006110 20 9 0,000 0,01833505 0,05072768 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,01833505 0,05067029 ! equilibrioception GO:0050957 20 9 0,000 0,01833505 0,05061304 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,01833505 0,05055591 ! chemosensory behavior GO:0007635 21 9 0,000 0,01833505 0,05049891 ! microtubule bundle formation GO:0001578 22 9 0,000 0,01833505 0,05044205 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,01833505 0,05038531 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,01833505 0,05032869 ! leukocyte degranulation GO:0043299 16 9 0,000 0,01833505 0,05027221 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,01833505 0,05021585 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,01833505 0,05015962 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,01833505 0,05010351 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,01833505 0,05004753 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,01833505 0,04999167 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,01833505 0,04993594 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,01833505 0,04988033 ! protein targeting to ER GO:0045047 25 9 0,000 0,01833505 0,04982485 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,01833505 0,04976949 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,01833505 0,04971425 ! T cell selection GO:0045058 27 9 0,000 0,01833505 0,04965913 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,01833505 0,04960414 ! glycine catabolic process GO:0006546 15 9 0,000 0,01833505 0,04954927 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,01833505 0,04949452 ! endosome organization GO:0007032 20 9 0,000 0,01833505 0,04943989 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,01833505 0,04938538 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,01833505 0,04933099 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,01833505 0,04927672 ! mannose metabolic process GO:0006013 13 9 0,000 0,01833505 0,04922257 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,01833505 0,04916854 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,01833505 0,04911462 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,01833505 0,04906083 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,01833505 0,04900715 ! receptor clustering GO:0043113 20 9 0,000 0,01833505 0,04895359 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,01833505 0,04890015 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,01833505 0,04884682 ! retinol metabolic process GO:0042572 20 9 0,000 0,01833505 0,04879361 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,01833505 0,04874052 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,01833505 0,04868754 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,01833505 0,04863468 ! macrophage differentiation GO:0030225 15 9 0,000 0,01833505 0,04858193 ! oligodendrocyte development GO:0014003 11 9 0,000 0,01833505 0,04852929 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,01833505 0,04847677 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,01833505 0,04842436 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,01833505 0,04837207 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,01833505 0,04831989 ! response to amine stimulus GO:0014075 13 9 0,000 0,01833505 0,04826782 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,01833505 0,04821586 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,01833505 0,04816402 ! erythrocyte development GO:0048821 17 9 0,000 0,01833505 0,04811228 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,01833505 0,04806066 ! renal water homeostasis GO:0003091 15 9 0,000 0,01833505 0,04800915 ! postreplication repair GO:0006301 25 9 0,000 0,01833505 0,04795775 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,01833505 0,04790646 ! icosanoid secretion GO:0032309 15 9 0,000 0,01833505 0,04785527 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,01833505 0,0478042 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,01833505 0,04775324 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,01833505 0,04770238 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,01833505 0,04765164 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,01833505 0,047601 ! sterol catabolic process GO:0016127 14 9 0,000 0,01833505 0,04755046 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,01833505 0,04750004 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,01833505 0,04744972 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,01833505 0,04739951 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,01833505 0,0473494 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,01833505 0,04729941 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,01833505 0,04724951 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,01833505 0,04719972 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,01833505 0,04715004 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,01833505 0,04710046 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,01833505 0,04705098 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,01833505 0,04700161 ! purine base metabolic process GO:0006144 25 9 0,000 0,01833505 0,04695234 ! pigment granule transport GO:0051904 17 9 0,000 0,01833505 0,04690318 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,01833505 0,04685412 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,01833505 0,04680516 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,01833505 0,0467563 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,01833505 0,04670755 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,01833505 0,04665889 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,01833505 0,04661034 ! mitochondrion localization GO:0051646 18 9 0,000 0,01833505 0,04656189 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0203517 0,0516295 ! regulation of developmental growth GO:0048638 16 10 0,000 0,0203517 0,05157594 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0203517 0,05152249 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0203517 0,05146916 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0203517 0,05141593 ! associative learning GO:0008306 21 10 0,000 0,0203517 0,05136282 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0203517 0,05130981 ! phosphate transport GO:0006817 24 10 0,000 0,0203517 0,05125691 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0203517 0,05120412 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0203517 0,05115145 ! CTP metabolic process GO:0046036 11 10 0,000 0,0203517 0,05109887 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0203517 0,05104641 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0203517 0,05099406 ! GTP metabolic process GO:0046039 11 10 0,000 0,0203517 0,05094181 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0203517 0,05088967 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0203517 0,05083763 ! social behavior GO:0035176 29 10 0,000 0,0203517 0,0507857 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0203517 0,05073388 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0203517 0,05068217 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0203517 0,05063055 ! androgen metabolic process GO:0008209 17 10 0,000 0,0203517 0,05057905 ! phospholipid efflux GO:0033700 19 10 0,000 0,0203517 0,05052765 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0203517 0,05047635 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0203517 0,05042516 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0203517 0,05037407 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0203517 0,05032308 ! lung alveolus development GO:0048286 26 10 0,000 0,0203517 0,0502722 ! pathogenesis GO:0009405 17 10 0,000 0,0203517 0,05022142 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0203517 0,05017074 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0203517 0,05012017 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0203517 0,05006969 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0203517 0,05001932 ! endoderm development GO:0007492 18 10 0,000 0,0203517 0,04996905 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0203517 0,04991888 ! arginine catabolic process GO:0006527 17 10 0,000 0,0203517 0,04986881 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0203517 0,04981884 ! proline metabolic process GO:0006560 13 10 0,000 0,0203517 0,04976897 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0203517 0,0497192 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0203517 0,04966954 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0203517 0,04961997 ! V(D)J recombination GO:0033151 34 10 0,000 0,0203517 0,04957049 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0203517 0,04952112 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0203517 0,04947185 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0203517 0,04942267 ! B cell proliferation GO:0042100 19 10 0,000 0,0203517 0,04937359 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0203517 0,04932461 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0203517 0,04927572 ! multicellular organism growth GO:0035264 19 10 0,000 0,0203517 0,04922694 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0203517 0,04917824 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0203517 0,04912965 ! ruffle organization GO:0031529 17 10 0,000 0,0203517 0,04908115 ! epithelial cell development GO:0002064 21 10 0,000 0,0203517 0,04903275 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0203517 0,04898444 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0203517 0,04893623 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0203517 0,04888811 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0203517 0,04884008 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0203517 0,04879215 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0203517 0,04874432 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0203517 0,04869658 ! motor axon guidance GO:0008045 22 10 0,000 0,0203517 0,04864893 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0203517 0,04860137 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0203517 0,04855391 ! protein heterooligomerization GO:0051291 17 10 0,000 0,0203517 0,04850654 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0203517 0,04845926 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0203517 0,04841208 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0203517 0,04836499 ! segment specification GO:0007379 15 10 0,000 0,0203517 0,04831798 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,0203517 0,04827107 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0203517 0,04822425 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0203517 0,04817752 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0203517 0,04813089 ! response to dsRNA GO:0043331 23 10 0,000 0,0203517 0,04808434 ! DNA ligation GO:0006266 18 10 0,000 0,0203517 0,04803788 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0203517 0,04799151 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0203517 0,04794523 ! melanosome localization GO:0032400 16 10 0,000 0,0203517 0,04789904 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0203517 0,04785294 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0203517 0,04780693 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0203517 0,047761 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0203517 0,04771517 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0203517 0,04766942 ! induction of an organ GO:0001759 17 10 0,000 0,0203517 0,04762376 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0203517 0,04757819 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0203517 0,0475327 ! protein sumoylation GO:0016925 17 10 0,000 0,0203517 0,0474873 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0203517 0,04744199 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0203517 0,04739676 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0203517 0,04735162 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0203517 0,04730657 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0203517 0,0472616 ! salivary gland development GO:0007431 28 10 0,000 0,0203517 0,04721672 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0203517 0,04717192 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0203517 0,04712721 ! midbrain development GO:0030901 14 10 0,000 0,0203517 0,04708258 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0203517 0,04703804 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0203517 0,04699358 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0203517 0,0469492 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0203517 0,04690491 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0203517 0,0468607 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0203517 0,04681658 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0203517 0,04677254 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0203517 0,04672858 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0203517 0,0466847 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,0203517 0,04664091 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,0203517 0,04659719 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0203517 0,04655356 ! blastocyst formation GO:0001825 18 10 0,000 0,0203517 0,04651001 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0203517 0,04646655 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0203517 0,04642316 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0203517 0,04637986 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0203517 0,04633663 ! response to nicotine GO:0035094 20 10 0,000 0,0203517 0,04629349 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0203517 0,04625042 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0203517 0,04620744 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02236426 0,0507297 ! respiratory burst GO:0045730 17 11 0,000 0,02236426 0,05068264 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02236426 0,05063567 ! neuron fate specification GO:0048665 18 11 0,000 0,02236426 0,05058879 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02236426 0,05054199 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02236426 0,05049528 ! thyroid gland development GO:0030878 26 11 0,000 0,02236426 0,05044865 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,02236426 0,05040211 ! synapsis GO:0007129 14 11 0,000 0,02236426 0,05035566 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02236426 0,05030929 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02236426 0,05026301 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02236426 0,05021681 ! response to pain GO:0048265 27 11 0,000 0,02236426 0,0501707 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02236426 0,05012467 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02236426 0,05007873 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02236426 0,05003287 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02236426 0,04998709 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02236426 0,0499414 ! bone resorption GO:0045453 16 11 0,000 0,02236426 0,04989579 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02236426 0,04985026 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,02236426 0,04980482 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02236426 0,04975946 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02236426 0,04971419 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02236426 0,04966899 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02236426 0,04962388 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02236426 0,04957885 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02236426 0,0495339 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02236426 0,04948903 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,02236426 0,04944424 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02236426 0,04939954 ! UV protection GO:0009650 20 11 0,000 0,02236426 0,04935491 ! adult heart development GO:0007512 16 11 0,000 0,02236426 0,04931037 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02236426 0,04926591 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02236426 0,04922152 ! macroautophagy GO:0016236 19 11 0,000 0,02236426 0,04917722 ! temperature homeostasis GO:0001659 18 11 0,000 0,02236426 0,04913299 ! behavioral fear response GO:0001662 27 11 0,000 0,02236426 0,04908885 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02236426 0,04904478 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02236426 0,0490008 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02236426 0,04895689 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02236426 0,04891306 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02236426 0,04886931 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02236426 0,04882564 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02236426 0,04878204 ! regulation of organ growth GO:0046620 14 11 0,000 0,02236426 0,04873853 ! pigment granule localization GO:0051875 20 11 0,000 0,02236426 0,04869509 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02236426 0,04865173 ! vasoconstriction GO:0042310 20 11 0,000 0,02236426 0,04860844 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02236426 0,04856524 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02236426 0,04852211 ! embryonic axis specification GO:0000578 19 11 0,000 0,02236426 0,04847905 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02236426 0,04843607 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02236426 0,04839317 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02236426 0,04835035 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02236426 0,0483076 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02236426 0,04826492 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02236426 0,04822232 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02236426 0,0481798 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02236426 0,04813735 ! prophase GO:0051324 17 11 0,000 0,02236426 0,04809497 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02236426 0,04805267 ! nucleosome positioning GO:0016584 15 11 0,000 0,02236426 0,04801045 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02236426 0,0479683 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02236426 0,04792622 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02236426 0,04788422 ! apical protein localization GO:0045176 18 11 0,000 0,02236426 0,04784229 ! acid secretion GO:0046717 20 11 0,000 0,02236426 0,04780043 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02236426 0,04775865 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02236426 0,04771693 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02236426 0,0476753 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02236426 0,04763373 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02236426 0,04759224 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02236426 0,04755082 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02236426 0,04750947 ! cholesterol efflux GO:0033344 21 11 0,000 0,02236426 0,04746819 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02236426 0,04742699 ! oocyte development GO:0048599 20 11 0,000 0,02236426 0,04738585 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02236426 0,04734479 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 19 11 0,000 0,02236426 0,0473038 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02236426 0,04726288 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02236426 0,04722203 ! activation of innate immune response GO:0002218 16 11 0,000 0,02236426 0,04718125 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02236426 0,04714054 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02236426 0,04709991 ! lysogeny GO:0030069 22 11 0,000 0,02236426 0,04705934 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02236426 0,04701884 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02236426 0,04697841 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02236426 0,04693805 ! regulation of embryonic development GO:0045995 35 11 0,000 0,02236426 0,04689776 ! nucleus localization GO:0051647 22 11 0,000 0,02236426 0,04685754 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,02437274 0,05102195 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,02437274 0,05097826 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,02437274 0,05093466 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,02437274 0,05089112 ! virus-host interaction GO:0019048 30 12 0,000 0,02437274 0,05084766 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,02437274 0,05080428 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02437274 0,05076097 ! protein complex disassembly GO:0043241 28 12 0,000 0,02437274 0,05071773 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,02437274 0,05067456 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,02437274 0,05063147 ! hippocampus development GO:0021766 29 12 0,000 0,02437274 0,05058846 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,02437274 0,05054551 ! T cell proliferation GO:0042098 32 12 0,000 0,02437274 0,05050264 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02437274 0,05045984 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,02437274 0,05041712 ! ventral spinal cord development GO:0021517 25 12 0,000 0,02437274 0,05037446 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,02437274 0,05033188 ! drug transport GO:0015893 16 12 0,000 0,02437274 0,05028937 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,02437274 0,05024693 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,02437274 0,05020456 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,02437274 0,05016227 ! polyamine metabolic process GO:0006595 18 12 0,000 0,02437274 0,05012004 ! focal adhesion formation GO:0048041 37 12 0,000 0,02437274 0,05007789 ! mitotic spindle organization GO:0007052 23 12 0,000 0,02437274 0,05003581 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,02437274 0,0499938 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,02437274 0,04995186 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,02437274 0,04990999 ! lipid digestion GO:0044241 21 12 0,000 0,02437274 0,04986819 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,02437274 0,04982645 ! entry into host cell GO:0030260 34 12 0,000 0,02437274 0,04978479 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02437274 0,0497432 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,02437274 0,04970168 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,02437274 0,04966023 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02437274 0,04961884 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,02437274 0,04957753 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,02437274 0,04953628 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,02437274 0,04949511 ! snRNA metabolic process GO:0016073 30 12 0,000 0,02437274 0,049454 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,02437274 0,04941296 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,02437274 0,04937198 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02437274 0,04933108 ! cranial nerve development GO:0021545 23 12 0,000 0,02437274 0,04929024 ! fucose catabolic process GO:0019317 25 12 0,000 0,02437274 0,04924947 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,02437274 0,04920877 ! histone acetylation GO:0016573 27 12 0,000 0,02437274 0,04916814 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,02437274 0,04912757 ! autonomic nervous system development GO:0048483 24 12 0,000 0,02437274 0,04908707 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,02437274 0,04904663 ! zymogen activation GO:0031638 18 12 0,000 0,02437274 0,04900627 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,02437274 0,04896596 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,02437274 0,04892573 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,02437274 0,04888556 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,02437274 0,04884546 ! oocyte differentiation GO:0009994 21 12 0,000 0,02437274 0,04880542 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,02437274 0,04876545 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,02437274 0,04872554 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,02437274 0,0486857 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,02437274 0,04864593 ! defense response to fungus GO:0050832 15 12 0,000 0,02437274 0,04860621 ! developmental induction GO:0031128 22 12 0,000 0,02437274 0,04856657 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,02437274 0,04852699 ! lamellipodium assembly GO:0030032 24 12 0,000 0,02437274 0,04848747 ! response to cold GO:0009409 17 12 0,000 0,02437274 0,04844802 ! establishment of cell polarity GO:0030010 21 12 0,000 0,02437274 0,04840863 ! regulation of synapse organization GO:0050807 18 12 0,000 0,02437274 0,0483693 ! localization within membrane GO:0051668 26 12 0,000 0,02437274 0,04833004 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,02637716 0,05226228 ! cGMP metabolic process GO:0046068 18 13 0,000 0,02637716 0,05221993 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,02637716 0,05217765 ! regulation of chemokine production GO:0032642 18 13 0,000 0,02637716 0,05213543 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,02637716 0,05209328 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,02637716 0,05205121 ! peroxisomal transport GO:0043574 28 13 0,000 0,02637716 0,0520092 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,02637716 0,05196725 ! cartilage condensation GO:0001502 22 13 0,000 0,02637716 0,05192538 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,02637716 0,05188357 ! organelle fusion GO:0048284 36 13 0,000 0,02637716 0,05184183 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,02637716 0,05180016 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,02637716 0,05175855 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,02637716 0,05171701 ! endocrine pancreas development GO:0031018 25 13 0,000 0,02637716 0,05167554 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,02637716 0,05163413 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,02637716 0,05159279 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,02637716 0,05155151 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,02637716 0,05151031 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,02637716 0,05146916 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,02637716 0,05142809 ! methionine metabolic process GO:0006555 31 13 0,000 0,02637716 0,05138708 ! plasma membrane organization GO:0007009 27 13 0,000 0,02637716 0,05134613 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,02637716 0,05130525 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,02637716 0,05126443 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,02637716 0,05122368 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,02637716 0,051183 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,02637716 0,05114238 ! cytokine metabolic process GO:0042107 24 13 0,000 0,02637716 0,05110182 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,02637716 0,05106133 ! exocrine system development GO:0035272 34 13 0,000 0,02637716 0,0510209 ! asymmetric protein localization GO:0008105 24 13 0,000 0,02637716 0,05098053 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,02637716 0,05094023 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,02637716 0,05089999 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,02637716 0,05085982 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,02637716 0,05081971 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,02637716 0,05077966 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,02637716 0,05073968 ! protein homotetramerization GO:0051289 24 13 0,000 0,02637716 0,05069976 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,02637716 0,0506599 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,02637716 0,0506201 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,02637716 0,05058037 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,02637716 0,0505407 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,02637716 0,05050109 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,02637716 0,05046155 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,02637716 0,05042206 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,02637716 0,05038264 ! histone methylation GO:0016571 29 13 0,000 0,02637716 0,05034328 ! chromatin silencing GO:0006342 29 13 0,000 0,02637716 0,05030398 ! gland morphogenesis GO:0022612 31 13 0,000 0,02637716 0,05026474 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,02637716 0,05022556 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,02637716 0,05018644 ! regulation of epidermis development GO:0045682 19 13 0,000 0,02637716 0,05014739 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,02637716 0,05010839 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,02637716 0,05006946 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,02637716 0,05003058 ! spleen development GO:0048536 24 13 0,000 0,02637716 0,04999177 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,02637716 0,04995302 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,02637716 0,04991432 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,02637716 0,04987569 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,02637716 0,04983712 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,02637716 0,0497986 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,02637716 0,04976015 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,02637716 0,04972175 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,02637716 0,04968342 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,02637716 0,04964514 ! insulin secretion GO:0030073 24 13 0,000 0,02637716 0,04960692 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,02637716 0,04956876 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,02637716 0,04953066 ! acrosome reaction GO:0007340 19 13 0,000 0,02637716 0,04949262 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,02637716 0,04945464 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,02637716 0,04941671 ! rRNA transcription GO:0009303 28 14 0,000 0,02837751 0,05312356 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,02837751 0,05308289 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,02837751 0,05304227 ! water transport GO:0006833 21 14 0,000 0,02837751 0,05300172 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,02837751 0,05296123 ! non-recombinational repair GO:0000726 29 14 0,000 0,02837751 0,0529208 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,02837751 0,05288044 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,02837751 0,05284013 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,02837751 0,05279989 ! RNA polyadenylation GO:0043631 32 14 0,000 0,02837751 0,0527597 ! lipid localization GO:0010876 32 14 0,000 0,02837751 0,05271958 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,02837751 0,05267952 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,02837751 0,05263952 ! regulated secretory pathway GO:0045055 24 14 0,000 0,02837751 0,05259958 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,02837751 0,0525597 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,02837751 0,05251989 ! arginine metabolic process GO:0006525 21 14 0,000 0,02837751 0,05248013 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,02837751 0,05244043 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,02837751 0,05240079 ! regulation of heart rate GO:0002027 25 14 0,000 0,02837751 0,05236122 ! fear response GO:0042596 34 14 0,000 0,02837751 0,0523217 ! organic alcohol transport GO:0015850 29 14 0,000 0,02837751 0,05228224 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,02837751 0,05224284 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,02837751 0,0522035 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,02837751 0,05216422 ! neutral amino acid transport GO:0015804 28 14 0,000 0,02837751 0,052125 ! bone mineralization GO:0030282 18 14 0,000 0,02837751 0,05208584 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,02837751 0,05204673 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,02837751 0,05200769 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,02837751 0,0519687 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,02837751 0,05192978 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,02837751 0,05189091 ! regulation of cellular pH GO:0030641 27 14 0,000 0,02837751 0,05185209 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,02837751 0,05181334 ! ribosome assembly GO:0042255 18 14 0,000 0,02837751 0,05177465 ! cerebellum development GO:0021549 23 14 0,000 0,02837751 0,05173601 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,02837751 0,05169743 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,02837751 0,0516589 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,02837751 0,05162044 ! response to gamma radiation GO:0010332 30 14 0,000 0,02837751 0,05158203 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,02837751 0,05154368 ! NADP metabolic process GO:0006739 24 14 0,000 0,02837751 0,05150539 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,02837751 0,05146715 ! oxygen transport GO:0015671 22 14 0,000 0,02837751 0,05142897 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,02837751 0,05139085 ! male genitalia development GO:0030539 26 14 0,000 0,02837751 0,05135278 ! regulation of RNA stability GO:0043487 33 14 0,000 0,02837751 0,05131477 ! regulation of axon extension GO:0030516 43 14 0,000 0,02837751 0,05127681 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,02837751 0,05123891 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,02837751 0,05120107 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0303738 0,05476251 ! lactation GO:0007595 30 15 0,000 0,0303738 0,05472213 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,0303738 0,0546818 ! reproductive cellular process GO:0048610 22 15 0,000 0,0303738 0,05464154 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0303738 0,05460133 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0303738 0,05456118 ! superoxide anion generation GO:0042554 22 15 0,000 0,0303738 0,05452109 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0303738 0,05448106 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,0303738 0,05444109 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0303738 0,05440118 ! copper ion transport GO:0006825 22 15 0,000 0,0303738 0,05436132 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,0303738 0,05432153 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0303738 0,05428179 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0303738 0,05424211 ! sulfate transport GO:0008272 27 15 0,000 0,0303738 0,05420249 ! response to cAMP GO:0051591 25 15 0,000 0,0303738 0,05416292 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0303738 0,05412342 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0303738 0,05408397 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0303738 0,05404458 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0303738 0,05400524 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0303738 0,05396597 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0303738 0,05392675 ! vesicle coating GO:0006901 38 15 0,000 0,0303738 0,05388759 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0303738 0,05384848 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0303738 0,05380943 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0303738 0,05377044 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0303738 0,0537315 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0303738 0,05369262 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0303738 0,0536538 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,0303738 0,05361503 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0303738 0,05357632 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,0303738 0,05353767 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0303738 0,05349907 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0303738 0,05346052 ! histone deacetylation GO:0016575 24 15 0,000 0,0303738 0,05342203 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0303738 0,0533836 ! water homeostasis GO:0030104 28 15 0,000 0,0303738 0,05334522 ! cofactor transport GO:0051181 30 15 0,000 0,0303738 0,0533069 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0303738 0,05326863 ! muscle maintenance GO:0046716 26 15 0,000 0,0303738 0,05323042 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0303738 0,05319226 ! intestinal absorption GO:0050892 31 15 0,000 0,0303738 0,05315416 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0303738 0,05311611 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0303738 0,05307811 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0303738 0,05304017 ! cell killing GO:0001906 32 15 0,000 0,0303738 0,05300229 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,0303738 0,05296446 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0303738 0,05292668 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0303738 0,05288896 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0303738 0,05285129 ! actin filament polymerization GO:0030041 27 15 0,000 0,0303738 0,05281367 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0303738 0,05277611 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,03236606 0,05619778 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,03236606 0,05615787 ! positive regulation of cell size GO:0045793 29 16 0,000 0,03236606 0,05611801 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,03236606 0,05607821 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,03236606 0,05603847 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,03236606 0,05599878 ! bone remodeling GO:0046849 28 16 0,000 0,03236606 0,05595915 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,03236606 0,05591957 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,03236606 0,05588005 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,03236606 0,05584059 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,03236606 0,05580118 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,03236606 0,05576183 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,03236606 0,05572253 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,03236606 0,05568329 ! startle response GO:0001964 28 16 0,000 0,03236606 0,05564411 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,03236606 0,05560498 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,03236606 0,0555659 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,03236606 0,05552688 ! protein polyubiquitination GO:0000209 41 16 0,000 0,03236606 0,05548791 ! glutamate metabolic process GO:0006536 25 16 0,000 0,03236606 0,055449 ! pituitary gland development GO:0021983 30 16 0,000 0,03236606 0,05541014 ! response to osmotic stress GO:0006970 27 16 0,000 0,03236606 0,05537134 ! lysosomal transport GO:0007041 31 16 0,000 0,03236606 0,05533259 ! fructose metabolic process GO:0006000 25 16 0,000 0,03236606 0,0552939 ! L-amino acid transport GO:0015807 33 16 0,000 0,03236606 0,05525526 ! stem cell development GO:0048864 46 16 0,000 0,03236606 0,05521667 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03236606 0,05517814 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03236606 0,05513966 ! intermediate filament-based process GO:0045103 36 16 0,000 0,03236606 0,05510124 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,03236606 0,05506287 ! negative regulation of immune response GO:0050777 38 16 0,000 0,03236606 0,05502455 ! axon cargo transport GO:0008088 46 16 0,000 0,03236606 0,05498628 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,03236606 0,05494807 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,03236606 0,05490991 ! DNA replication initiation GO:0006270 28 16 0,000 0,03236606 0,05487181 ! neuron recognition GO:0008038 40 16 0,000 0,03236606 0,05483376 ! mRNA splice site selection GO:0006376 44 16 0,000 0,03236606 0,05479576 ! tissue regeneration GO:0042246 27 16 0,000 0,03236606 0,05475781 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,03236606 0,05471991 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,03236606 0,05468207 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,03236606 0,05464428 ! biomineral formation GO:0031214 22 16 0,000 0,03236606 0,05460654 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,03236606 0,05456886 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,03236606 0,05453122 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,03236606 0,05449364 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03236606 0,05445611 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,03236606 0,05441863 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,03236606 0,05438121 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,03236606 0,05434383 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,03236606 0,05430651 ! peptide hormone processing GO:0016486 27 16 0,000 0,03236606 0,05426924 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,03435427 0,05756343 ! metencephalon development GO:0022037 32 17 0,000 0,03435427 0,05752398 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,03435427 0,05748458 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,03435427 0,05744523 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,03435427 0,05740594 ! signal complex assembly GO:0007172 47 17 0,000 0,03435427 0,0573667 ! filopodium assembly GO:0046847 42 17 0,000 0,03435427 0,05732752 ! endothelial cell migration GO:0043542 31 17 0,000 0,03435427 0,05728838 ! gene silencing by RNA GO:0031047 38 17 0,000 0,03435427 0,05724931 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,03435427 0,05721028 ! glial cell development GO:0021782 28 17 0,000 0,03435427 0,05717131 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,03435427 0,05713239 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,03435427 0,05709353 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,03435427 0,05705471 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,03435427 0,05701595 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,03435427 0,05697725 ! myoblast differentiation GO:0045445 50 17 0,000 0,03435427 0,05693859 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,03435427 0,05689999 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,03435427 0,05686144 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,03435427 0,05682294 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,03435427 0,05678449 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,03435427 0,0567461 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,03435427 0,05670776 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,03435427 0,05666947 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,03435427 0,05663123 ! membrane budding GO:0006900 42 17 0,000 0,03435427 0,05659304 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,03435427 0,05655491 ! regulation of protein binding GO:0043393 33 17 0,000 0,03435427 0,05651682 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,03435427 0,05647879 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,03435427 0,05644081 ! genitalia development GO:0048806 32 17 0,000 0,03435427 0,05640288 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,03435427 0,056365 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,03435427 0,05632717 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,03435427 0,05628939 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,03435427 0,05625166 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,03435427 0,05621399 ! steroid catabolic process GO:0006706 34 17 0,000 0,03435427 0,05617636 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,03435427 0,05613878 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,03435427 0,05610126 ! gas transport GO:0015669 26 17 0,000 0,03435427 0,05606378 ! organic cation transport GO:0015695 32 17 0,000 0,03435427 0,05602636 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,03435427 0,05598898 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,03435427 0,05595166 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,03435427 0,05591438 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,03633846 0,05910443 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,03633846 0,0590651 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,03633846 0,05902583 ! limbic system development GO:0021761 40 18 0,000 0,03633846 0,05898661 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,03633846 0,05894744 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,03633846 0,05890833 ! adult walking behavior GO:0007628 36 18 0,000 0,03633846 0,05886926 ! patterning of blood vessels GO:0001569 43 18 0,000 0,03633846 0,05883025 ! heart looping GO:0001947 34 18 0,000 0,03633846 0,05879129 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,03633846 0,05875238 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,03633846 0,05871352 ! centrosome cycle GO:0007098 26 18 0,000 0,03633846 0,05867472 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,03633846 0,05863596 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,03633846 0,05859726 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,03633846 0,05855861 ! glycine metabolic process GO:0006544 30 18 0,000 0,03633846 0,05852 ! glutamine metabolic process GO:0006541 29 18 0,000 0,03633846 0,05848145 ! response to retinoic acid GO:0032526 31 18 0,000 0,03633846 0,05844295 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,03633846 0,0584045 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,03633846 0,05836611 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,03633846 0,05832776 ! DNA integration GO:0015074 32 18 0,000 0,03633846 0,05828946 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,03633846 0,05825121 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,03633846 0,05821301 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,03633846 0,05817487 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,03633846 0,05813677 ! neural crest cell migration GO:0001755 41 18 0,000 0,03633846 0,05809872 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,03633846 0,05806072 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,03633846 0,05802278 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,03633846 0,05798488 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,03633846 0,05794703 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,03633846 0,05790923 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,03633846 0,05787148 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,03633846 0,05783378 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,03633846 0,05779612 ! detection of bacterium GO:0016045 22 18 0,000 0,03633846 0,05775852 ! nerve development GO:0021675 34 18 0,000 0,03633846 0,05772097 ! defense response to virus GO:0051607 43 18 0,000 0,03633846 0,05768346 ! microspike assembly GO:0030035 46 18 0,000 0,03633846 0,057646 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,03633846 0,0576086 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,03633846 0,05757124 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,03831862 0,06066908 ! positive regulation of translation GO:0045727 31 19 0,000 0,03831862 0,06062978 ! negative regulation of defense response GO:0031348 27 19 0,000 0,03831862 0,06059054 ! neuron maturation GO:0042551 46 19 0,000 0,03831862 0,06055135 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,03831862 0,06051221 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,03831862 0,06047312 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,03831862 0,06043408 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,03831862 0,06039509 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,03831862 0,06035615 ! inositol metabolic process GO:0006020 33 19 0,000 0,03831862 0,06031726 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,03831862 0,06027842 ! memory GO:0007613 34 19 0,000 0,03831862 0,06023963 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,03831862 0,06020089 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,03831862 0,0601622 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,03831862 0,06012356 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,03831862 0,06008497 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,03831862 0,06004643 ! cerebral cortex development GO:0021987 40 19 0,000 0,03831862 0,06000794 ! pigmentation during development GO:0048066 42 19 0,000 0,03831862 0,0599695 ! response to vitamin A GO:0033189 32 19 0,000 0,03831862 0,05993111 ! heme metabolic process GO:0042168 40 19 0,000 0,03831862 0,05989276 ! neuromuscular junction development GO:0007528 43 19 0,000 0,03831862 0,05985447 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,03831862 0,05981622 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,03831862 0,05977802 ! response to fungus GO:0009620 26 19 0,000 0,03831862 0,05973988 ! peptide cross-linking GO:0018149 39 19 0,000 0,03831862 0,05970178 ! protein export from nucleus GO:0006611 40 19 0,000 0,03831862 0,05966373 ! heart process GO:0003015 32 19 0,000 0,03831862 0,05962572 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,03831862 0,05958777 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,03831862 0,05954986 ! cellular pigmentation GO:0033059 37 19 0,000 0,03831862 0,05951201 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,03831862 0,0594742 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,03831862 0,05943644 ! vitamin transport GO:0051180 31 19 0,000 0,03831862 0,05939872 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,03831862 0,05936106 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,03831862 0,05932344 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,03831862 0,05928587 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,03831862 0,05924835 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,03831862 0,05921087 ! cilium assembly GO:0042384 38 19 0,000 0,03831862 0,05917344 ! peptide hormone secretion GO:0030072 32 19 0,000 0,03831862 0,05913606 ! protein secretion GO:0009306 45 20 0,000 0,04029477 0,06214654 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,04029477 0,06210733 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,04029477 0,06206817 ! positive regulation of ossification GO:0045778 50 20 0,000 0,04029477 0,06202906 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,04029477 0,06199 ! skin development GO:0043588 42 20 0,000 0,04029477 0,06195099 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,04029477 0,06191203 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,04029477 0,06187311 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,04029477 0,06183425 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,04029477 0,06179543 ! response to vitamin GO:0033273 36 20 0,000 0,04029477 0,06175666 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,04029477 0,06171794 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,04029477 0,06167927 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,04029477 0,06164065 ! bile acid metabolic process GO:0008206 34 20 0,000 0,04029477 0,06160208 ! response to alkaloid GO:0043279 38 20 0,000 0,04029477 0,06156355 ! retinoid metabolic process GO:0001523 34 20 0,000 0,04029477 0,06152508 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,04029477 0,06148665 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,04029477 0,06144827 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,04029477 0,06140993 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,04029477 0,06137165 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,04029477 0,06133341 ! actin filament bundle formation GO:0051017 47 20 0,000 0,04029477 0,06129522 ! body fluid secretion GO:0007589 33 20 0,000 0,04029477 0,06125708 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,04029477 0,06121898 ! peptide secretion GO:0002790 38 20 0,000 0,04029477 0,06118093 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,04029477 0,06114293 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,04029477 0,06110498 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,04029477 0,06106707 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,04029477 0,06102921 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,04029477 0,0609914 ! cell-cell junction organization GO:0045216 43 20 0,000 0,04029477 0,06095364 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,04029477 0,06091592 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,04029477 0,06087824 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,04029477 0,06084062 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,04029477 0,06080304 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,04029477 0,06076551 ! regulation of glucose import GO:0046324 30 20 0,000 0,04029477 0,06072802 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,04029477 0,06069058 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,04029477 0,06065319 ! negative regulation of translation GO:0017148 32 20 0,000 0,04029477 0,06061584 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,04029477 0,06057854 ! regulation of cell killing GO:0031341 46 21 0,000 0,04226691 0,06350435 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,04226691 0,06346532 ! hormone secretion GO:0046879 39 21 0,000 0,04226691 0,06342633 ! cAMP metabolic process GO:0046058 41 21 0,000 0,04226691 0,0633874 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,04226691 0,06334851 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,04226691 0,06330967 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,04226691 0,06327088 ! ovarian follicle development GO:0001541 39 21 0,000 0,04226691 0,06323213 ! smooth muscle contraction GO:0006939 48 21 0,000 0,04226691 0,06319343 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,04226691 0,06315478 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,04226691 0,06311618 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,04226691 0,06307763 ! plasma membrane fusion GO:0045026 33 21 0,000 0,04226691 0,06303912 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,04226691 0,06300065 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,04226691 0,06296224 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,04226691 0,06292387 ! sensory perception of pain GO:0019233 33 21 0,000 0,04226691 0,06288555 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,04226691 0,06284727 ! diencephalon development GO:0021536 36 21 0,000 0,04226691 0,06280905 ! collagen fibril organization GO:0030199 62 21 0,000 0,04226691 0,06277086 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,04226691 0,06273273 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,04226691 0,06269464 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,04226691 0,0626566 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,04226691 0,0626186 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,04226691 0,06258065 ! collagen catabolic process GO:0030574 29 21 0,000 0,04226691 0,06254275 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,04226691 0,06250489 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,04226691 0,06246707 ! sperm-egg recognition GO:0035036 23 21 0,000 0,04226691 0,06242931 ! actin filament-based movement GO:0030048 47 21 0,000 0,04226691 0,06239158 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,04226691 0,06235391 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,04423506 0,06521802 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,04423506 0,06517868 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,04423506 0,0651394 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,04423506 0,06510016 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,04423506 0,06506096 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,04423506 0,06502182 ! microtubule-based transport GO:0010970 59 22 0,000 0,04423506 0,06498272 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,04423506 0,06494366 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,04423506 0,06490466 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,04423506 0,0648657 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,04423506 0,06482679 ! cellular response to starvation GO:0009267 37 22 0,000 0,04423506 0,06478792 ! vacuolar transport GO:0007034 41 22 0,000 0,04423506 0,06474911 ! central nervous system neuron development GO:0021954 47 22 0,000 0,04423506 0,06471033 ! fucose metabolic process GO:0006004 44 22 0,000 0,04423506 0,06467161 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,04423506 0,06463293 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,04423506 0,0645943 ! ureteric bud development GO:0001657 50 22 0,000 0,04423506 0,06455571 ! cell aging GO:0007569 48 22 0,000 0,04423506 0,06451717 ! stem cell differentiation GO:0048863 57 22 0,000 0,04423506 0,06447867 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,04423506 0,06444023 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,04423506 0,06440182 ! cytolysis GO:0019835 27 22 0,000 0,04423506 0,06436346 ! renal system process GO:0003014 42 22 0,000 0,04423506 0,06432515 ! vasodilation GO:0042311 40 22 0,000 0,04423506 0,06428689 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,04423506 0,06424867 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,04423506 0,06421049 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,04423506 0,06417236 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,04423506 0,06413428 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,04423506 0,06409624 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,04423506 0,06405824 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,04423506 0,06402029 ! sarcomere organization GO:0045214 32 22 0,000 0,04423506 0,06398239 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,04423506 0,06394453 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,04423506 0,06390672 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,04423506 0,06386895 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,04423506 0,06383122 ! gut development GO:0048565 44 22 0,000 0,04423506 0,06379354 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,04423506 0,0637559 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,04423506 0,06371831 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,04423506 0,06368076 ! protein stabilization GO:0050821 41 22 0,000 0,04423506 0,06364326 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,04619922 0,06643007 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,04619922 0,066391 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,04619922 0,06635197 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,04619922 0,06631298 ! gluconeogenesis GO:0006094 38 23 0,000 0,04619922 0,06627404 ! glycerol metabolic process GO:0006071 40 23 0,000 0,04619922 0,06623515 ! viral genome replication GO:0019079 44 23 0,000 0,04619922 0,0661963 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,04619922 0,0661575 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,04619922 0,06611874 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,04619922 0,06608003 ! regeneration GO:0031099 42 23 0,000 0,04619922 0,06604137 ! axis specification GO:0009798 43 23 0,000 0,04619922 0,06600275 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,04619922 0,06596417 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,04619922 0,06592564 ! response to ethanol GO:0045471 47 23 0,000 0,04619922 0,06588716 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,04619922 0,06584871 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,04619922 0,06581032 ! peroxisome organization GO:0007031 43 23 0,000 0,04619922 0,06577197 ! lysosome organization GO:0007040 47 23 0,000 0,04619922 0,06573366 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,04619922 0,0656954 ! vesicle targeting GO:0006903 49 23 0,000 0,04619922 0,06565718 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,04619922 0,06561901 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,04619922 0,06558088 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,04619922 0,0655428 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,04619922 0,06550476 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,04619922 0,06546676 ! DNA modification GO:0006304 36 23 0,000 0,04619922 0,06542881 ! fatty acid transport GO:0015908 47 23 0,000 0,04619922 0,0653909 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,04619922 0,06535304 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,04619922 0,06531522 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,04619922 0,06527744 ! hormone transport GO:0009914 41 23 0,000 0,04619922 0,06523971 ! cell-cell recognition GO:0009988 28 23 0,000 0,04619922 0,06520202 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,04619922 0,06516437 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,04619922 0,06512677 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,04619922 0,06508921 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,0481594 0,06781176 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,0481594 0,0677727 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,0481594 0,06773368 ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,0481594 0,06769471 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,0481594 0,06765578 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,0481594 0,0676169 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,0481594 0,06757806 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,0481594 0,06753927 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,0481594 0,06750052 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,0481594 0,06746182 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,0481594 0,06742316 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,0481594 0,06738454 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,0481594 0,06734597 ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,0481594 0,06730744 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,0481594 0,06726896 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,0481594 0,06723052 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,0481594 0,06719212 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,0481594 0,06715377 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,0481594 0,06711546 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,0481594 0,0670772 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,0481594 0,06703898 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,0481594 0,0670008 ! membrane depolarization GO:0051899 45 24 0,000 0,0481594 0,06696267 ! pallium development GO:0021543 56 24 0,000 0,0481594 0,06692458 ! oogenesis GO:0048477 44 24 0,000 0,0481594 0,06688653 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,0481594 0,06684853 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,0481594 0,06681057 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,0481594 0,06677265 ! platelet activation GO:0030168 41 24 0,000 0,0481594 0,06673478 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,0481594 0,06669694 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,0481594 0,06665916 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,0481594 0,06662141 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,0481594 0,06658371 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,0481594 0,06654605 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,0481594 0,06650843 ! regulation of amine transport GO:0051952 41 24 0,000 0,0481594 0,06647085 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,0481594 0,06643332 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,0501156 0,06909279 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,0501156 0,06905382 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,0501156 0,06901489 ! leukocyte adhesion GO:0007159 55 25 0,000 0,0501156 0,06897601 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,0501156 0,06893717 ! phototransduction GO:0007602 37 25 0,000 0,0501156 0,06889838 ! keratinization GO:0031424 37 25 0,000 0,0501156 0,06885963 ! vasculogenesis GO:0001570 49 25 0,000 0,0501156 0,06882092 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,0501156 0,06878226 ! vacuole organization GO:0007033 49 25 0,000 0,0501156 0,06874364 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,0501156 0,06870506 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,0501156 0,06866653 ! receptor metabolic process GO:0043112 53 25 0,000 0,0501156 0,06862804 ! chromosome condensation GO:0030261 48 25 0,000 0,0501156 0,06858959 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,0501156 0,06855118 ! regulation of behavior GO:0050795 48 25 0,000 0,0501156 0,06851282 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,0501156 0,06847451 ! interaction with host GO:0051701 66 25 0,000 0,0501156 0,06843623 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,0501156 0,068398 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,0501156 0,06835981 ! immunoglobulin production GO:0002377 62 25 0,000 0,0501156 0,06832166 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,0501156 0,06828356 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,0501156 0,06824549 ! liver development GO:0001889 55 25 0,000 0,0501156 0,06820747 ! protein tetramerization GO:0051262 57 25 0,000 0,0501156 0,0681695 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,05206784 0,07078561 ! myelination GO:0042552 50 26 0,000 0,05206784 0,07074624 ! initiation of viral infection GO:0019059 60 26 0,000 0,05206784 0,07070691 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,05206784 0,07066763 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,05206784 0,07062839 ! molting cycle process GO:0022404 52 26 0,000 0,05206784 0,0705892 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,05206784 0,07055005 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,05206784 0,07051094 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,05206784 0,07047188 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,05206784 0,07043285 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,05206784 0,07039388 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,05206784 0,07035494 ! digestive system process GO:0022600 49 26 0,000 0,05206784 0,07031605 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,05206784 0,0702772 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,05206784 0,0702384 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,05206784 0,07019963 ! osteoblast differentiation GO:0001649 63 26 0,000 0,05206784 0,07016091 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,05206784 0,07012224 ! neural crest cell development GO:0014032 59 26 0,000 0,05206784 0,0700836 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,05206784 0,07004501 ! negative regulation of cell development GO:0010721 83 26 0,000 0,05206784 0,07000646 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,05206784 0,06996795 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,05206784 0,06992949 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,05206784 0,06989106 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,05206784 0,06985268 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,05206784 0,06981434 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,05206784 0,06977605 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,05206784 0,06973779 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,05206784 0,06969958 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,05206784 0,06966141 ! blastocyst development GO:0001824 50 26 0,000 0,05206784 0,06962328 ! telomere organization GO:0032200 46 26 0,000 0,05206784 0,06958519 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,05206784 0,06954715 ! neural tube closure GO:0001843 58 26 0,000 0,05206784 0,06950914 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,05206784 0,06947118 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,05206784 0,06943326 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,05206784 0,06939538 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,05401612 0,07195277 ! embryonic pattern specification GO:0009880 49 27 0,000 0,05401612 0,07191356 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,05401612 0,07187439 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,05401612 0,07183527 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,05401612 0,07179618 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,05401612 0,07175714 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,05401612 0,07171814 ! iron ion transport GO:0006826 65 27 0,000 0,05401612 0,07167919 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,05401612 0,07164027 ! superoxide metabolic process GO:0006801 41 27 0,000 0,05401612 0,0716014 ! tube lumen formation GO:0035148 59 27 0,000 0,05401612 0,07156257 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,05401612 0,07152379 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,05401612 0,07148504 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,05401612 0,07144634 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,05401612 0,07140768 ! response to starvation GO:0042594 47 27 0,000 0,05401612 0,07136906 ! response to toxin GO:0009636 49 27 0,000 0,05401612 0,07133048 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,05401612 0,07129194 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,05401612 0,07125345 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,05401612 0,07121499 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,05401612 0,07117658 ! leukocyte proliferation GO:0070661 59 27 0,000 0,05401612 0,07113821 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,05596045 0,07365915 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,05596045 0,07361949 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,05596045 0,07357986 ! protein amino acid acylation GO:0043543 59 28 0,000 0,05596045 0,07354028 ! vesicle docking GO:0048278 55 28 0,000 0,05596045 0,07350075 ! circadian rhythm GO:0007623 56 28 0,000 0,05596045 0,07346125 ! dendrite development GO:0016358 67 28 0,000 0,05596045 0,0734218 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,05596045 0,07338239 ! fat cell differentiation GO:0045444 57 28 0,000 0,05596045 0,07334302 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,05596045 0,07330369 ! sperm motility GO:0030317 37 28 0,000 0,05596045 0,07326441 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,05596045 0,07322517 ! base-excision repair GO:0006284 41 28 0,000 0,05596045 0,07318597 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,05596045 0,07314681 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,05596045 0,07310769 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,05596045 0,07306862 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,05596045 0,07302959 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,05596045 0,0729906 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,05596045 0,07295165 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,05596045 0,07291274 ! glutathione metabolic process GO:0006749 42 28 0,000 0,05596045 0,07287387 ! lipid oxidation GO:0034440 48 28 0,000 0,05596045 0,07283505 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,05596045 0,07279627 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,05596045 0,07275752 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,05790084 0,0752403 ! translational initiation GO:0006413 66 29 0,000 0,05790084 0,0752003 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,05790084 0,07516034 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,05790084 0,07512042 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,05790084 0,07508055 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,05790084 0,07504072 ! autophagy GO:0006914 47 29 0,000 0,05790084 0,07500093 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,05790084 0,07496119 ! primary neural tube formation GO:0014020 61 29 0,000 0,05790084 0,07492148 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,05790084 0,07488182 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,05790084 0,0748422 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,05790084 0,07480262 ! somitogenesis GO:0001756 52 29 0,000 0,05790084 0,07476309 ! synaptogenesis GO:0007416 46 29 0,000 0,05790084 0,07472359 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,05790084 0,07468414 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,05790084 0,07464473 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,05790084 0,07460536 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,05790084 0,07456603 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,0598373 0,07701924 ! phenol metabolic process GO:0018958 56 30 0,000 0,0598373 0,07697868 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,0598373 0,07693817 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,0598373 0,0768977 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,0598373 0,07685727 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,0598373 0,07681688 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,0598373 0,07677653 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,0598373 0,07673623 ! acute-phase response GO:0006953 50 30 0,000 0,0598373 0,07669597 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,0598373 0,07665575 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,0598373 0,07661558 ! myofibril assembly GO:0030239 50 30 0,000 0,0598373 0,07657544 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,0598373 0,07653535 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,0598373 0,0764953 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,0598373 0,07645529 ! cell fate determination GO:0001709 64 30 0,000 0,0598373 0,07641533 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,0598373 0,0763754 ! phospholipid transport GO:0015914 65 30 0,000 0,0598373 0,07633552 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,0598373 0,07629568 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,0598373 0,07625588 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,0598373 0,07621612 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,0598373 0,07617641 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,0598373 0,07613673 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,06176983 0,07855476 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,06176983 0,07851389 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,06176983 0,07847306 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,06176983 0,07843227 ! cell junction assembly GO:0034329 85 31 0,000 0,06176983 0,07839153 ! regulation of innate immune response GO:0045088 57 31 0,000 0,06176983 0,07835083 ! ovulation cycle process GO:0022602 55 31 0,000 0,06176983 0,07831017 ! peptide transport GO:0015833 60 31 0,000 0,06176983 0,07826955 ! male gonad development GO:0008584 56 31 0,000 0,06176983 0,07822898 ! iron ion homeostasis GO:0055072 60 31 0,000 0,06176983 0,07818844 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,06176983 0,07814795 ! detection of light stimulus GO:0009583 44 31 0,000 0,06176983 0,0781075 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,06176983 0,07806709 ! natural killer cell activation GO:0030101 50 31 0,000 0,06176983 0,07802673 ! ensheathment of neurons GO:0007272 64 31 0,000 0,06176983 0,0779864 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,06176983 0,07794612 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,06176983 0,07790588 ! eye morphogenesis GO:0048592 65 31 0,000 0,06176983 0,07786568 ! response to heat GO:0009408 54 31 0,000 0,06176983 0,07782553 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,06176983 0,07778541 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,06369844 0,08017274 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,06369844 0,08013146 ! collagen metabolic process GO:0032963 49 32 0,000 0,06369844 0,08009022 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,06369844 0,08004902 ! spindle organization GO:0007051 50 32 0,000 0,06369844 0,08000786 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,06369844 0,07996675 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,06369844 0,07992568 ! metanephros development GO:0001656 81 32 0,000 0,06369844 0,07988465 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,06369844 0,07984366 ! muscle cell development GO:0055001 52 32 0,000 0,06369844 0,07980271 ! mesoderm formation GO:0001707 73 32 0,000 0,06369844 0,07976181 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,06369844 0,07972095 ! ovulation cycle GO:0042698 57 32 0,000 0,06369844 0,07968013 ! peripheral nervous system development GO:0007422 68 32 0,000 0,06369844 0,07963935 ! BMP signaling pathway GO:0030509 71 32 0,000 0,06369844 0,07959862 ! hindbrain development GO:0030902 65 32 0,000 0,06369844 0,07955792 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,06369844 0,07951727 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,06369844 0,07947666 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,06369844 0,07943609 ! gene silencing GO:0016458 71 32 0,000 0,06369844 0,07939556 ! regulation of pH GO:0006885 56 33 0,000 0,06562314 0,08175285 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,06562314 0,08171118 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,06562314 0,08166956 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,06562314 0,08162797 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,06562314 0,08158643 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,06562314 0,08154493 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,06562314 0,08150348 ! response to ionizing radiation GO:0010212 74 33 0,000 0,06562314 0,08146206 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,06562314 0,08142069 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,06562314 0,08137936 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,06562314 0,08133807 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,06562314 0,08129683 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,06562314 0,08125562 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,06562314 0,08121446 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,06562314 0,08117334 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,06754394 0,08350701 ! glial cell differentiation GO:0010001 67 34 0,000 0,06754394 0,08346477 ! post-embryonic development GO:0009791 76 34 0,000 0,06754394 0,08342257 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,06754394 0,08338042 ! cholesterol transport GO:0030301 62 34 0,000 0,06754394 0,08333831 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,06754394 0,08329624 ! spliceosome assembly GO:0000245 75 34 0,000 0,06754394 0,08325421 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,06754394 0,08321223 ! formation of primary germ layer GO:0001704 76 34 0,000 0,06754394 0,08317029 ! cell fate specification GO:0001708 56 34 0,000 0,06754394 0,08312839 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,06754394 0,08308653 ! adult locomotory behavior GO:0008344 62 34 0,000 0,06754394 0,08304472 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,06754394 0,08300294 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,06946085 0,08531566 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,06946085 0,08527279 ! negative regulation of secretion GO:0051048 68 35 0,000 0,06946085 0,08522996 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,06946085 0,08518717 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,06946085 0,08514443 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,06946085 0,08510173 ! membrane docking GO:0022406 69 35 0,000 0,06946085 0,08505907 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,06946085 0,08501646 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,06946085 0,08497389 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,06946085 0,08493136 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,06946085 0,08488887 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,06946085 0,08484643 ! ceramide metabolic process GO:0006672 72 35 0,000 0,06946085 0,08480402 ! telencephalon development GO:0021537 81 35 0,000 0,06946085 0,08476166 ! sterol transport GO:0015918 63 35 0,000 0,06946085 0,08471935 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,06946085 0,08467707 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,06946085 0,08463484 ! placenta development GO:0001890 53 35 0,000 0,06946085 0,08459265 ! vesicle localization GO:0051648 70 35 0,000 0,06946085 0,0845505 ! regulation of muscle development GO:0048634 82 36 0,000 0,07137387 0,08683583 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,07137387 0,08679261 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,07137387 0,08674943 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,07137387 0,08670629 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,07137387 0,0866632 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,07137387 0,08662015 ! positive regulation of cell development GO:0010720 85 36 0,000 0,07137387 0,08657714 ! protein targeting to membrane GO:0006612 75 36 0,000 0,07137387 0,08653417 ! regulation of proteolysis GO:0030162 77 36 0,000 0,07137387 0,08649125 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,07137387 0,08644837 ! aerobic respiration GO:0009060 56 36 0,000 0,07137387 0,08640553 ! cytokine production GO:0001816 68 36 0,000 0,07137387 0,08636273 ! embryonic organ development GO:0048568 67 36 0,000 0,07137387 0,08631998 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,07137387 0,08627727 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,07137387 0,0862346 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,07328301 0,08849747 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,07328301 0,08845375 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,07328301 0,08841006 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,07328301 0,08836643 ! sister chromatid segregation GO:0000819 65 37 0,000 0,07328301 0,08832283 ! odontogenesis GO:0042476 74 37 0,000 0,07328301 0,08827928 ! actomyosin structure organization GO:0031032 68 37 0,000 0,07328301 0,08823577 ! cell junction organization GO:0034330 96 37 0,000 0,07328301 0,08819231 ! tissue remodeling GO:0048771 78 37 0,000 0,07328301 0,08814888 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,07328301 0,0881055 ! female gonad development GO:0008585 71 37 0,000 0,07328301 0,08806216 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,07328301 0,08801887 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,07328301 0,08797562 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,07518827 0,09021854 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,07518827 0,09017425 ! meiosis I GO:0007127 74 38 0,000 0,07518827 0,09013001 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,07518827 0,0900858 ! organic anion transport GO:0015711 82 38 0,000 0,07518827 0,09004164 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,07518827 0,08999753 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,07518827 0,08995345 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,07518827 0,08990942 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,07518827 0,08986544 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,07518827 0,08982149 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,07518827 0,08977759 ! regulation of protein stability GO:0031647 77 38 0,000 0,07518827 0,08973373 ! spermatid development GO:0007286 69 38 0,000 0,07518827 0,08968992 ! glycogen metabolic process GO:0005977 63 38 0,000 0,07518827 0,08964614 ! pigment metabolic process GO:0042440 87 38 0,000 0,07518827 0,08960241 ! neural tube formation GO:0001841 79 38 0,000 0,07518827 0,08955873 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,07708968 0,09177879 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,07708968 0,09173409 ! negative regulation of binding GO:0051100 71 39 0,000 0,07708968 0,09168943 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,07708968 0,09164481 ! carbohydrate homeostasis GO:0033500 59 39 0,000 0,07708968 0,09160023 GO:0042593|glucose homeostasis, ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,07708968 0,0915557 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,07708968 0,09151122 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,07708968 0,09146677 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,07708968 0,09142237 ! glucan metabolic process GO:0044042 64 39 0,000 0,07708968 0,09137801 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,07898723 0,09358186 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,07898723 0,0935365 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,07898723 0,09349118 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,07898723 0,0934459 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,07898723 0,09340067 ! mismatch repair GO:0006298 58 40 0,000 0,07898723 0,09335549 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,07898723 0,09331034 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,07898723 0,09326524 ! RNA export from nucleus GO:0006405 61 41 0,000 0,08088093 0,09545512 ! mRNA catabolic process GO:0006402 79 41 0,000 0,08088093 0,09540903 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,08088093 0,09536298 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,08088093 0,09531698 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,08088093 0,09527102 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,08088093 0,09522511 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,08088093 0,09517924 ! gliogenesis GO:0042063 91 41 0,000 0,08088093 0,09513341 ! feeding behavior GO:0007631 69 41 0,000 0,08088093 0,09508763 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,08088093 0,0950419 ! mesenchymal cell development GO:0014031 94 41 0,000 0,08088093 0,0949962 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,08088093 0,09495055 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,08088093 0,09490495 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,08088093 0,09485939 ! spermatid differentiation GO:0048515 73 41 0,000 0,08088093 0,09481387 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,08088093 0,09476839 ! RNA modification GO:0009451 64 41 0,000 0,08088093 0,09472296 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,08277079 0,09688981 ! ear morphogenesis GO:0042471 64 42 0,000 0,08277079 0,0968434 ! organic ether metabolic process GO:0018904 59 42 0,000 0,08277079 0,09679705 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,08277079 0,09675073 ! T cell differentiation GO:0030217 93 42 0,000 0,08277079 0,09670446 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,08277079 0,09665824 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,08277079 0,09661205 ! regulation of protein secretion GO:0050708 77 42 0,000 0,08277079 0,09656592 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,08277079 0,09651982 ! cytokinesis GO:0000910 84 42 0,000 0,08277079 0,09647377 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,08277079 0,09642777 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,08465681 0,09857798 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,08465681 0,09853101 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,08465681 0,09848409 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,08465681 0,09843722 ! regulation of tube size GO:0035150 76 43 0,000 0,08465681 0,09839039 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,08465681 0,0983436 ! glucose transport GO:0015758 66 43 0,000 0,08465681 0,09829686 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,08465681 0,09825016 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,08465681 0,09820351 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,08465681 0,0981569 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,08465681 0,09811034 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,08465681 0,09806382 ! segmentation GO:0035282 78 43 0,000 0,08465681 0,09801734 ! ion transmembrane transport GO:0034220 79 43 0,000 0,08465681 0,09797091 ! neuron migration GO:0001764 85 43 0,000 0,08465681 0,09792452 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,08465681 0,09787818 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,08653901 0,10000701 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,08653901 0,09995972 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,08653901 0,09991248 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,08653901 0,09986529 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,08653901 0,09981814 ! hexose transport GO:0008645 68 44 0,000 0,08653901 0,09977103 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,08653901 0,09972397 ! striated muscle contraction GO:0006941 85 44 0,000 0,08653901 0,09967695 ! phagocytosis GO:0006909 105 44 0,000 0,08653901 0,09962998 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,08653901 0,09958305 ! double-strand break repair GO:0006302 85 44 0,000 0,08653901 0,09953616 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,0884174 0,1016488 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,0884174 0,10160099 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,0884174 0,10155322 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,0884174 0,1015055 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,0884174 0,10145782 ! B cell differentiation GO:0030183 124 45 0,000 0,0884174 0,10141019 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,0884174 0,1013626 ! female gamete generation GO:0007292 71 45 0,000 0,0884174 0,10131506 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,0884174 0,10126756 ! polyol metabolic process GO:0019751 77 45 0,000 0,0884174 0,10122011 ! developmental growth GO:0048589 88 45 0,000 0,0884174 0,1011727 ! maintenance of location in cell GO:0051651 101 45 0,000 0,0884174 0,10112533 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,09029197 0,10322101 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,09029197 0,10317273 ! glycolysis GO:0006096 71 46 0,000 0,09029197 0,10312449 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,09029197 0,1030763 ! leukocyte migration GO:0050900 75 46 0,000 0,09029197 0,10302816 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,09029197 0,10298006 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,09029197 0,10293201 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,09029197 0,102884 ! pigmentation GO:0043473 103 46 0,000 0,09029197 0,10283603 ! neural tube development GO:0021915 91 47 0,000 0,09216275 0,1049178 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,09216275 0,10486893 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,09402972 0,10694349 ! positive regulation of defense response GO:0031349 88 48 0,000 0,09402972 0,10689373 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,09402972 0,10684401 ! mitochondrial transport GO:0006839 94 48 0,000 0,09402972 0,10679434 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,09402972 0,10674471 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,09402972 0,10669513 ! endosome transport GO:0016197 127 48 0,000 0,09402972 0,1066456 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,09402972 0,10659611 ! male sex differentiation GO:0046661 93 48 0,000 0,09402972 0,10654667 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,09402972 0,10649727 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,09402972 0,10644792 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,09402972 0,10639862 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,09402972 0,10634936 ! methylation GO:0032259 97 48 0,000 0,09402972 0,10630015 ! response to calcium ion GO:0051592 94 49 0,000 0,09589292 0,10835633 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,09589292 0,10830624 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,09589292 0,10825619 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,09589292 0,10820619 ! JNK cascade GO:0007254 106 49 0,000 0,09589292 0,10815623 ! regulation of action potential GO:0001508 102 50 0,000 0,09775233 0,11020255 ! regulation of ion transport GO:0043269 86 50 0,000 0,09775233 0,11015172 ! endocrine system development GO:0035270 109 50 0,000 0,09775233 0,11010094 ! activation of caspase activity GO:0006919 95 50 0,000 0,09775233 0,1100502 ! regulation of ossification GO:0030278 123 50 0,000 0,09775233 0,10999951 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,09775233 0,10994887 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,09775233 0,10989827 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,09775233 0,10984772 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,09775233 0,10979721 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,09960797 0,11183008 ! viral infectious cycle GO:0019058 104 51 0,000 0,09960797 0,11177872 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,09960797 0,11172739 ! peptide metabolic process GO:0006518 80 51 0,000 0,09960797 0,11167612 ! response to temperature stimulus GO:0009266 84 51 0,000 0,09960797 0,11162489 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,09960797 0,11157371 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,10145984 0,11359596 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,10145984 0,11354393 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,10145984 0,11349194 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,10145984 0,11344 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,10145984 0,1133881 ! excretion GO:0007588 87 52 0,000 0,10145984 0,11333626 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,10145984 0,11328446 ! histone modification GO:0016570 104 52 0,000 0,10145984 0,11323271 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,10145984 0,113181 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,10145984 0,11312934 ! amino acid activation GO:0043038 98 52 0,000 0,10145984 0,11307773 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,10330796 0,11508497 ! positive regulation of growth GO:0045927 96 53 0,000 0,10330796 0,11503252 ! inner ear development GO:0048839 89 53 0,000 0,10330796 0,11498011 ! chromatin remodeling GO:0006338 122 53 0,000 0,10330796 0,11492775 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,10330796 0,11487544 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,10330796 0,11482318 ! vesicle organization GO:0016050 127 53 0,000 0,10330796 0,11477096 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,10330796 0,1147188 ! cartilage development GO:0051216 99 53 0,000 0,10330796 0,11466667 ! synapse organization GO:0050808 102 53 0,000 0,10330796 0,1146146 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,10515233 0,11660787 ! regulation of translational initiation GO:0006446 87 54 0,000 0,10515233 0,11655497 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,10515233 0,11650211 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,10515233 0,11644929 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,10515233 0,11639653 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,10515233 0,11634382 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,10515233 0,11629115 ! membrane fusion GO:0006944 122 54 0,000 0,10515233 0,11623853 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,10515233 0,11618595 ! covalent chromatin modification GO:0016569 115 54 0,000 0,10515233 0,11613343 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,10515233 0,11608095 ! regulation of cell shape GO:0008360 142 54 0,000 0,10515233 0,11602852 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,10515233 0,11597614 ! RNA catabolic process GO:0006401 103 55 0,000 0,10699296 0,11795298 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,10699296 0,11789977 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,10699296 0,11784662 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,10699296 0,11779351 ! cell recognition GO:0008037 98 55 0,000 0,10699296 0,11774045 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,10699296 0,11768744 ! cell maturation GO:0048469 107 55 0,000 0,10699296 0,11763447 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,10699296 0,11758156 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,10699296 0,11752869 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,10882985 0,11949273 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,10882985 0,11943905 ! glucose catabolic process GO:0006007 88 56 0,000 0,10882985 0,11938542 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,10882985 0,11933183 ! chloride transport GO:0006821 102 57 0,000 0,11066302 0,12128746 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,11066302 0,12123307 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,11066302 0,12117873 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 0,000 0,11066302 0,12112444 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,11066302 0,1210702 ! heart morphogenesis GO:0003007 105 57 0,000 0,11066302 0,121016 ! regulation of actin filament length GO:0030832 118 58 0,000 0,11249247 0,12296156 ! positive regulation of cell migration GO:0030335 137 58 0,000 0,11249247 0,12290657 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,11249247 0,12285163 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,11249247 0,12279674 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,11249247 0,12274189 ! aging GO:0007568 112 58 0,000 0,11249247 0,1226871 ! gastrulation GO:0007369 122 58 0,000 0,11249247 0,12263235 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,11249247 0,12257765 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,11249247 0,122523 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,11249247 0,1224684 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,11249247 0,12241385 ! maintenance of location GO:0051235 124 58 0,000 0,11249247 0,12235935 ! nuclear export GO:0051168 110 59 0,000 0,1143182 0,12428988 ! establishment of organelle localization GO:0051656 122 59 0,000 0,1143182 0,12423459 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,11614023 0,12615855 ! regulation of endocytosis GO:0030100 104 60 0,000 0,11614023 0,12610248 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,11614023 0,12604646 ! adult behavior GO:0030534 104 60 0,000 0,11614023 0,12599049 ! kidney development GO:0001822 133 60 0,000 0,11614023 0,12593457 ! positive regulation of secretion GO:0051047 110 61 0,000 0,11795857 0,1278495 ! regulation of cellular component size GO:0032535 125 61 0,000 0,11795857 0,12779281 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,11795857 0,12773616 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,11795857 0,12767956 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,11795857 0,12762302 ! regulation of heart contraction GO:0008016 123 61 0,000 0,11795857 0,12756652 ! camera-type eye development GO:0043010 126 61 0,000 0,11795857 0,12751008 ! proton transport GO:0015992 117 61 0,000 0,11795857 0,12745368 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,11795857 0,12739734 ! viral reproductive process GO:0022415 132 62 0,000 0,11977321 0,12930002 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,11977321 0,12924291 ! tRNA processing GO:0008033 102 62 0,000 0,11977321 0,12918585 ! regulation of homeostatic process GO:0032844 148 62 0,000 0,11977321 0,12912884 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,12158417 0,13102344 ! regulation of mitosis GO:0007088 112 63 0,000 0,12158417 0,13096567 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,12158417 0,13090795 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,12158417 0,13085028 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,12158417 0,13079266 ! hydrogen transport GO:0006818 121 64 0,000 0,12339146 0,13267841 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,12339146 0,13262003 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,12339146 0,13256171 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,12339146 0,13250344 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,12519508 0,13438119 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,12519508 0,13432217 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,12519508 0,1342632 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,12519508 0,13420429 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,12519508 0,13414543 ! positive regulation of cell motion GO:0051272 157 65 0,000 0,12519508 0,13408662 ! ear development GO:0043583 114 66 0,000 0,12699504 0,13595481 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,12699504 0,13589526 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,12699504 0,13583576 ! activation of MAPK activity GO:0000187 124 67 0,000 0,12879135 0,13769683 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,12879135 0,1376366 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,12879135 0,13757641 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,12879135 0,13751628 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,12879135 0,13745621 ! secondary metabolic process GO:0019748 125 67 0,000 0,12879135 0,13739618 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,12879135 0,13733621 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,13058401 0,13918705 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,13058401 0,13912635 ! hexose catabolic process GO:0019320 113 68 0,000 0,13058401 0,13906571 ! extracellular matrix organization GO:0030198 146 68 0,000 0,13058401 0,13900511 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,13058401 0,13894457 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,13058401 0,13888408 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,13058401 0,13882364 ! viral reproduction GO:0016032 142 68 0,000 0,13058401 0,13876326 ! regulation of lipase activity GO:0060191 137 68 0,000 0,13058401 0,13870293 ! adaptive immune response GO:0002250 126 68 0,000 0,13058401 0,13864265 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,13058401 0,13858242 ! cell projection assembly GO:0030031 138 68 0,000 0,13058401 0,13852224 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,13237303 0,14035908 ! lung development GO:0030324 165 69 0,000 0,13237303 0,14029818 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,13237303 0,14023734 ! urogenital system development GO:0001655 149 69 0,000 0,13237303 0,14017655 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,13237303 0,14011582 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,13237303 0,14005514 ! developmental maturation GO:0021700 128 69 0,000 0,13237303 0,13999451 ! single fertilization GO:0007338 83 69 0,000 0,13237303 0,13993393 ! cell redox homeostasis GO:0045454 114 70 0,000 0,13415842 0,14175996 ! germ cell development GO:0007281 133 70 0,000 0,13415842 0,14169867 ! activation of immune response GO:0002253 120 70 0,000 0,13415842 0,14163743 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,13415842 0,14157625 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,13594019 0,14339459 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,13594019 0,14333271 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,13594019 0,14327087 ! appendage morphogenesis GO:0035107 150 72 0,000 0,13771834 0,14508232 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,13771834 0,14501979 ! respiratory tube development GO:0030323 171 72 0,000 0,13771834 0,14495731 ! actin filament organization GO:0007015 167 72 0,000 0,13771834 0,14489488 ! B cell activation GO:0042113 179 72 0,000 0,13771834 0,1448325 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,13771834 0,14477018 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,13771834 0,14470792 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,13771834 0,1446457 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,13771834 0,14458354 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,13771834 0,14452144 ! appendage development GO:0048736 151 73 0,000 0,13949288 0,14632079 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,13949288 0,14625799 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,13949288 0,14619524 ! regulation of immune effector process GO:0002697 156 73 0,000 0,13949288 0,14613255 ! acute inflammatory response GO:0002526 118 74 0,000 0,14126382 0,14792435 ! amino acid transport GO:0006865 148 74 0,000 0,14126382 0,14786098 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,14126382 0,14779765 ! respiratory system development GO:0060541 175 74 0,000 0,14126382 0,14773438 ! organelle localization GO:0051640 155 74 0,000 0,14126382 0,14767117 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,14303117 0,14945472 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,14303117 0,14939083 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,14303117 0,14932698 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,14303117 0,1492632 ! eye development GO:0001654 155 75 0,000 0,14303117 0,14919946 ! axon guidance GO:0007411 162 75 0,000 0,14303117 0,14913578 ! rhythmic process GO:0048511 142 75 0,000 0,14303117 0,14907216 ! cell-matrix adhesion GO:0007160 181 76 0,000 0,14479493 0,15084606 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,14479493 0,15078176 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,14479493 0,15071751 ! regulation of blood pressure GO:0008217 134 76 0,000 0,14479493 0,15065332 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,14479493 0,15058919 ! amine catabolic process GO:0009310 136 77 0,000 0,1465551 0,15235494 ! neurotransmitter transport GO:0006836 142 77 0,000 0,1465551 0,15229014 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,1465551 0,15222539 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,1465551 0,1521607 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,1465551 0,15209606 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,1465551 0,15203147 ! regulation of catabolic process GO:0009894 173 77 0,000 0,1465551 0,15196694 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,14831171 0,15372317 ! antigen processing and presentation GO:0019882 117 78 0,000 0,14831171 0,15365797 ! fertilization GO:0009566 99 78 0,000 0,14831171 0,15359284 ! blood coagulation GO:0007596 151 79 0,000 0,15006475 0,15534245 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,15006475 0,15527665 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,15006475 0,15521091 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,15006475 0,15514523 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,15006475 0,1550796 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,15181422 0,15682121 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,15181422 0,15675492 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,15181422 0,1566887 ! meiosis GO:0007126 143 81 0,000 0,15356015 0,15842375 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,15356015 0,15835688 ! response to hypoxia GO:0001666 178 81 0,000 0,15356015 0,15829006 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,15356015 0,1582233 ! cell-substrate adhesion GO:0031589 189 82 0,000 0,15530253 0,15995113 ! protein import into nucleus GO:0006606 174 82 0,000 0,15530253 0,15988373 ! meiotic cell cycle GO:0051321 144 82 0,000 0,15530253 0,15981638 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,15704138 0,16153772 ! exocytosis GO:0006887 153 83 0,000 0,15704138 0,16146973 ! response to oxygen levels GO:0070482 183 83 0,000 0,15704138 0,1614018 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,15704138 0,16133393 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,15704138 0,16126612 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,15704138 0,16119836 ! nuclear import GO:0051170 177 83 0,000 0,15704138 0,16113065 ! inorganic anion transport GO:0015698 156 83 0,000 0,15704138 0,16106301 ! response to metal ion GO:0010038 158 84 0,000 0,15877669 0,16277443 ! T cell activation GO:0042110 189 84 0,000 0,15877669 0,16270615 ! digestion GO:0007586 130 84 0,000 0,15877669 0,16263793 ! regulation of ligase activity GO:0051340 147 84 0,000 0,15877669 0,16256977 ! hemostasis GO:0007599 165 85 0,000 0,16050848 0,16427408 ! negative regulation of transport GO:0051051 164 85 0,000 0,16050848 0,16420529 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,16050848 0,16413655 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,16050848 0,16406788 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,16050848 0,16399926 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,16223676 0,16569582 ! regulation of lyase activity GO:0051339 169 86 0,000 0,16223676 0,16562658 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,16396152 0,16731746 ! alcohol catabolic process GO:0046164 142 87 0,000 0,16396152 0,1672476 ! nucleosome assembly GO:0006334 126 87 0,000 0,16396152 0,1671778 ! cellular respiration GO:0045333 143 88 0,000 0,16568279 0,16886235 ! amine biosynthetic process GO:0009309 146 88 0,000 0,16568279 0,16879193 ! sensory perception of smell GO:0007608 117 88 0,000 0,16568279 0,16872157 ! chromatin assembly GO:0031497 128 88 0,000 0,16568279 0,16865127 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,16568279 0,16858103 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,16740055 0,17025793 ! tube morphogenesis GO:0035239 194 89 0,000 0,16740055 0,17018708 ! cellular defense response GO:0006968 123 89 0,000 0,16740055 0,17011629 ! protein localization in nucleus GO:0034504 192 89 0,000 0,16740055 0,17004555 ! regulation of neurological system process GO:0031644 175 89 0,000 0,16740055 0,16997488 ! response to inorganic substance GO:0010035 173 90 0,000 0,16911483 0,17164418 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,16911483 0,1715729 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,16911483 0,17150167 ! response to unfolded protein GO:0006986 139 90 0,000 0,16911483 0,17143051 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,16911483 0,17135941 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,17082563 0,17302115 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,17082563 0,17294945 ! gland development GO:0048732 220 91 0,000 0,17082563 0,1728778 ! defense response to bacterium GO:0042742 112 91 0,000 0,17082563 0,17280622 ! bone development GO:0060348 206 92 0,000 0,17253295 0,17446109 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,17253295 0,17438891 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,17253295 0,17431679 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,17423681 0,17596549 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,17423681 0,17589278 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,17423681 0,17582013 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,17423681 0,17574753 ! vitamin metabolic process GO:0006766 153 93 0,000 0,17423681 0,175675 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,1759372 0,17731625 ! female pregnancy GO:0007565 166 94 0,000 0,1759372 0,17724313 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,1759372 0,17717007 ! regulation of membrane potential GO:0042391 179 94 0,000 0,1759372 0,17709707 ! regulation of defense response GO:0031347 171 95 0,000 0,17763415 0,17873156 ! nucleosome organization GO:0034728 143 95 0,000 0,17763415 0,17865797 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,17763415 0,17858445 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,17763415 0,17851099 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,17763415 0,17843759 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,17763415 0,17836425 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,17763415 0,17829097 ! response to protein stimulus GO:0051789 158 96 0,000 0,17932764 0,17991681 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,1810177 0,18153786 ! leukocyte differentiation GO:0002521 232 98 0,000 0,18270432 0,18315414 ! forebrain development GO:0030900 210 98 0,000 0,18270432 0,18307902 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,18270432 0,18300396 ! skeletal muscle tissue development GO:0007519 223 100 0,000 0,18606729 0,18629606 GO:0060538|skeletal muscle organ development, ! mRNA transport GO:0051028 185 100 0,000 0,18606729 0,18621974 ! positive regulation of immune response GO:0050778 175 100 0,000 0,18606729 0,18614349 ! hormone metabolic process GO:0042445 171 100 0,000 0,18606729 0,18606729