pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/585-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of lipid kinase activity GO:0043550 17 8 3,000 3,184E-09 7,779E-06 ! nuclear migration GO:0007097 13 6 2,000 3,562E-07 4,351E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 3,562E-07 2,9E-04 GO:0031272|regulation of pseudopodium assembly, ! interaction with host GO:0051701 66 25 3,000 5,56E-07 3,396E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 7,682E-07 3,753E-04 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 8,944E-07 3,642E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 9,935E-07 3,467E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 9,935E-07 3,034E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,487E-06 4,037E-04 ! macrophage differentiation GO:0030225 15 9 2,000 1,487E-06 3,634E-04 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 3,000 2,001E-06 4,445E-04 ! nucleus localization GO:0051647 22 11 2,000 2,91E-06 5,925E-04 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 3,16E-06 5,938E-04 ! regulation of cell projection assembly GO:0060491 33 12 2,000 3,873E-06 6,758E-04 ! response to insulin stimulus GO:0032868 98 47 3,000 7,498E-06 1,221E-03 ! filopodium assembly GO:0046847 42 17 2,000 1,186E-05 1,81E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,42E-05 2,041E-03 ! microspike assembly GO:0030035 46 18 2,000 1,42E-05 1,927E-03 ! viral reproductive process GO:0022415 132 62 3,000 2,275E-05 2,925E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,301E-05 2,811E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 2,581E-05 3,002E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 2,916E-05 3,238E-03 ! viral reproduction GO:0016032 142 68 3,000 3,281E-05 3,485E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 3,949E-05 4,02E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 3,949E-05 3,859E-03 ! protein tetramerization GO:0051262 57 25 2,000 3,949E-05 3,711E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 4,58E-05 4,144E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 5,003E-05 4,365E-03 ! mitochondrial membrane organization GO:0007006 60 27 2,000 5,003E-05 4,215E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 5,354E-05 4,36E-03 ! protein oligomerization GO:0051259 149 79 3,000 5,921E-05 4,666E-03 ! regulation of peptidase activity GO:0052547 150 82 3,000 6,85E-05 5,23E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 6,884E-05 5,096E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 6,884E-05 4,946E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 6,905E-05 4,82E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 7,63E-05 5,178E-03 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 7,883E-05 5,205E-03 ! protein refolding GO:0042026 15 6 1,000 1,031E-04 6,627E-03 ! interaction with symbiont GO:0051702 14 6 1,000 1,031E-04 6,457E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 1,031E-04 6,296E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,031E-04 6,142E-03 ! leukocyte differentiation GO:0002521 232 98 3,000 1,37E-04 7,968E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 1,441E-04 8,185E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 1,441E-04 7,999E-03 ! male sex determination GO:0030238 15 7 1,000 1,441E-04 7,821E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 1,441E-04 7,651E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,441E-04 7,488E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,441E-04 7,332E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 1,775E-04 8,85E-03 ! chaperone-mediated protein complex assembly GO:0051131 13 8 1,000 1,918E-04 9,369E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,918E-04 9,186E-03 ! outer mitochondrial membrane organization GO:0007008 16 8 1,000 1,918E-04 9,009E-03 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! ER overload response GO:0006983 13 8 1,000 1,918E-04 8,839E-03 ! response to tumor cell GO:0002347 16 8 1,000 1,918E-04 8,675E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 1,918E-04 8,517E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,345E-04 0,01022987 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,461E-04 0,01054858 ! regulation of glycolysis GO:0006110 20 9 1,000 2,461E-04 0,01036671 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 1,000 2,461E-04 0,010191 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 2,504E-04 0,01019448 ! mitochondrial transport GO:0006839 94 48 2,000 2,842E-04 0,01138148 ! positive regulation of DNA binding GO:0043388 83 48 2,000 2,842E-04 0,01119791 ! regulation of developmental growth GO:0048638 16 10 1,000 3,071E-04 0,01190938 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 3,071E-04 0,0117233 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 3,071E-04 0,01154294 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 1,000 3,071E-04 0,01136805 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 3,071E-04 0,01119837 ! protein heterooligomerization GO:0051291 17 10 1,000 3,071E-04 0,01103369 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 3,071E-04 0,01087378 GO:0043470|regulation of carbohydrate catabolic process, ! activation of caspase activity GO:0006919 95 50 2,000 3,208E-04 0,01119643 ! regulation of cell projection organization GO:0031344 135 51 2,000 3,402E-04 0,01170624 ! viral infectious cycle GO:0019058 104 51 2,000 3,402E-04 0,01154366 ! positive regulation of binding GO:0051099 88 52 2,000 3,604E-04 0,01205951 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 3,747E-04 0,01237084 ! regulation of intracellular pH GO:0051453 21 11 1,000 3,747E-04 0,0122059 ! regulation of embryonic development GO:0045995 35 11 1,000 3,747E-04 0,0120453 ! response to UV GO:0009411 120 55 2,000 4,253E-04 0,01349459 ! regulation of DNA replication GO:0006275 105 56 2,000 4,485E-04 0,01404876 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 4,489E-04 0,0138815 ! virus-host interaction GO:0019048 30 12 1,000 4,489E-04 0,01370798 ! regulation of B cell proliferation GO:0030888 22 12 1,000 4,489E-04 0,01353875 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 4,489E-04 0,01337364 ! entry into host cell GO:0030260 34 12 1,000 4,489E-04 0,01321251 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 4,489E-04 0,01305522 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,489E-04 0,01290163 ! positive regulation of caspase activity GO:0043280 108 57 2,000 4,726E-04 0,0134241 GO:0010952|positive regulation of peptidase activity, ! positive regulation of cell migration GO:0030335 137 58 2,000 4,974E-04 0,01396689 ! establishment of organelle localization GO:0051656 122 59 2,000 5,23E-04 0,01452013 ! response to X-ray GO:0010165 28 13 1,000 5,296E-04 0,01453703 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 5,296E-04 0,0143755 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 5,296E-04 0,01421753 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 5,296E-04 0,01406299 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 27 14 1,000 6,168E-04 0,01620246 ! response to gamma radiation GO:0010332 30 14 1,000 6,168E-04 0,01603009 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 6,168E-04 0,01586135 ! regulation of protein complex assembly GO:0043254 132 63 2,000 6,34E-04 0,01613507 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 6,64E-04 0,01672211 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 6,64E-04 0,01655147 ! positive regulation of cell motion GO:0051272 157 65 2,000 6,948E-04 0,01714431 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 7,105E-04 0,01735655 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 7,105E-04 0,0171847 ! G1/S transition checkpoint GO:0031575 37 15 1,000 7,105E-04 0,01701623 ! cell killing GO:0001906 32 15 1,000 7,105E-04 0,01685102 ! negative regulation of cell growth GO:0030308 142 67 2,000 7,591E-04 0,01783042 ! myeloid cell differentiation GO:0030099 126 67 2,000 7,591E-04 0,01766061 ! cell projection assembly GO:0030031 138 68 2,000 7,926E-04 0,01826651 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 8,106E-04 0,01850646 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 8,106E-04 0,01833511 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 8,106E-04 0,0181669 ! negative regulation of cell size GO:0045792 144 69 2,000 8,27E-04 0,01836729 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 8,27E-04 0,01820182 ! negative regulation of kinase activity GO:0033673 145 70 2,000 8,624E-04 0,0188111 ! gene silencing by RNA GO:0031047 38 17 1,000 9,171E-04 0,01982615 ! complement activation, alternative pathway GO:0006957 19 17 1,000 9,171E-04 0,01965224 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 9,36E-04 0,01988428 ! negative regulation of transferase activity GO:0051348 155 74 2,000 1,014E-03 0,02134474 ! organelle localization GO:0051640 155 74 2,000 1,014E-03 0,02116231 ! cell-substrate junction assembly GO:0007044 56 18 1,000 1,03E-03 0,02132257 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,03E-03 0,02114338 ! cell-matrix adhesion GO:0007160 181 76 2,000 1,095E-03 0,02229105 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 1,149E-03 0,02320027 ! memory GO:0007613 34 19 1,000 1,149E-03 0,0230101 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 1,149E-03 0,02282303 ! blood coagulation GO:0007596 151 79 2,000 1,225E-03 0,02412746 GO:0050817|coagulation, ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,275E-03 0,02491026 ! protein amino acid acetylation GO:0006473 41 20 1,000 1,275E-03 0,02471256 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 1,275E-03 0,02451797 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,275E-03 0,02432643 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 1,275E-03 0,02413785 ! cell-substrate adhesion GO:0031589 189 82 2,000 1,364E-03 0,02562612 ! lipid phosphorylation GO:0046834 43 21 1,000 1,406E-03 0,02622619 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 1,406E-03 0,02602751 ! hemostasis GO:0007599 165 85 2,000 1,512E-03 0,02777662 ! negative regulation of growth GO:0045926 168 85 2,000 1,512E-03 0,02756934 ! regulation of neuron differentiation GO:0045664 187 85 2,000 1,512E-03 0,02736512 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 1,544E-03 0,02774042 ! cellular response to starvation GO:0009267 37 22 1,000 1,544E-03 0,02753794 ! cell aging GO:0007569 48 22 1,000 1,544E-03 0,02733838 ! cytolysis GO:0019835 27 22 1,000 1,544E-03 0,02714171 ! G1 phase GO:0051318 44 22 1,000 1,544E-03 0,02694784 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 1,544E-03 0,02675672 ! positive regulation of B cell activation GO:0050871 42 22 1,000 1,544E-03 0,02656829 ! mitochondrion organization GO:0007005 159 87 2,000 1,617E-03 0,02761855 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,688E-03 0,02864513 ! viral genome replication GO:0019079 44 23 1,000 1,688E-03 0,02844758 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 1,688E-03 0,02825273 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 1,688E-03 0,02806054 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 1,725E-03 0,02848237 ! regulation of DNA binding GO:0051101 167 89 2,000 1,725E-03 0,02829122 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 1,839E-03 0,02994771 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 1,839E-03 0,02974938 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 1,839E-03 0,02955366 ! sex determination GO:0007530 48 24 1,000 1,839E-03 0,0293605 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 1,839E-03 0,02916985 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 1,995E-03 0,03144767 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 1,995E-03 0,03124609 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 1,995E-03 0,03104707 ! negative regulation of DNA replication GO:0008156 45 25 1,000 1,995E-03 0,03085057 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 2,079E-03 0,03194647 ! initiation of viral infection GO:0019059 60 26 1,000 2,158E-03 0,03294698 ! protein amino acid alkylation GO:0008213 59 26 1,000 2,158E-03 0,03274234 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 2,158E-03 0,03254023 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 2,158E-03 0,0323406 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 2,158E-03 0,0321434 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,158E-03 0,03194859 ! negative regulation of cell development GO:0010721 83 26 1,000 2,158E-03 0,03175613 GO:0050768|negative regulation of neurogenesis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 2,158E-03 0,03156597 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 2,206E-03 0,03208412 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,272E-03 0,03283892 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 2,272E-03 0,03264575 ! response to starvation GO:0042594 47 27 1,000 2,326E-03 0,03323661 ! cellular response to nutrient levels GO:0031669 45 27 1,000 2,326E-03 0,03304337 ! protein amino acid acylation GO:0043543 59 28 1,000 2,501E-03 0,03531872 ! base-excision repair GO:0006284 41 28 1,000 2,501E-03 0,03511574 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 2,501E-03 0,03491508 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 2,682E-03 0,03722429 ! somitogenesis GO:0001756 52 29 1,000 2,682E-03 0,03701398 ! complement activation, classical pathway GO:0006958 51 30 1,000 2,868E-03 0,03936735 ! regulation of B cell activation GO:0050864 55 30 1,000 2,868E-03 0,03914742 ! cell junction assembly GO:0034329 85 31 1,000 3,061E-03 0,04154334 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 3,259E-03 0,04399246 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 3,259E-03 0,04375074 ! positive regulation of catabolic process GO:0009896 72 32 1,000 3,259E-03 0,04351167 ! gene silencing GO:0016458 71 32 1,000 3,259E-03 0,04327519 ! regulation of pH GO:0006885 56 33 1,000 3,464E-03 0,04573953 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 3,464E-03 0,04549361 ! response to ionizing radiation GO:0010212 74 33 1,000 3,464E-03 0,04525033 ! DNA damage checkpoint GO:0000077 78 35 1,000 3,89E-03 0,05054727 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 3,89E-03 0,05027982 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 4,112E-03 0,05286647 ! cell junction organization GO:0034330 96 37 1,000 4,339E-03 0,05549951 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 4,572E-03 0,05817782 ! DNA integrity checkpoint GO:0031570 82 38 1,000 4,572E-03 0,05787638 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 4,811E-03 0,06058639 ! carbohydrate homeostasis GO:0033500 59 39 1,000 4,811E-03 0,06027569 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 4,811E-03 0,05996816 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 5,056E-03 0,06269636 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 1,000 5,056E-03 0,06237971 ! gliogenesis GO:0042063 91 41 1,000 5,306E-03 0,06513737 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 5,306E-03 0,06481169 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 5,562E-03 0,06759775 ! T cell differentiation GO:0030217 93 42 1,000 5,562E-03 0,06726311 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 5,823E-03 0,07007654 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 5,823E-03 0,06973303 ! neuron migration GO:0001764 85 43 1,000 5,823E-03 0,06939287 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 5,823E-03 0,06905601 ! double-strand break repair GO:0006302 85 44 1,000 6,09E-03 0,07187167 ! receptor-mediated endocytosis GO:0006898 98 45 1,000 6,362E-03 0,07472482 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 6,362E-03 0,07436729 ! biopolymer methylation GO:0043414 91 45 1,000 6,362E-03 0,07401316 ! B cell differentiation GO:0030183 124 45 1,000 6,362E-03 0,07366239 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 6,64E-03 0,07651627 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 6,64E-03 0,07615704 ! positive regulation of protein transport GO:0051222 80 46 1,000 6,64E-03 0,07580117 ! methylation GO:0032259 97 48 1,000 7,212E-03 0,08194698 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 7,506E-03 0,08489314 ! protein homooligomerization GO:0051260 84 49 1,000 7,506E-03 0,08450192 ! regulation of ossification GO:0030278 123 50 1,000 7,805E-03 0,08746926 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 7,805E-03 0,08706986 GO:0019724|B cell mediated immunity, ! excretion GO:0007588 87 52 1,000 8,42E-03 0,09349985 ! histone modification GO:0016570 104 52 1,000 8,42E-03 0,09307677 ! positive regulation of growth GO:0045927 96 53 1,000 8,735E-03 0,09612661 ! chromatin remodeling GO:0006338 122 53 1,000 8,735E-03 0,09569555 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 8,735E-03 0,09526833 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 1,000 8,735E-03 0,09484492 ! covalent chromatin modification GO:0016569 115 54 1,000 9,056E-03 0,09788948 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,01004818 0,1081397 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01004818 0,1076654 ! heart morphogenesis GO:0003007 105 57 1,000 0,01004818 0,10719525 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,01004818 0,10672918 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,01004818 0,10626715 ! aging GO:0007568 112 58 1,000 0,01038928 0,10940094 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01038928 0,10893141 ! lipid modification GO:0030258 112 60 1,000 0,01108671 0,11574712 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,01180424 0,12271387 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,01180424 0,12219389 ! regulation of mitosis GO:0007088 112 63 1,000 0,01217048 0,12545347 GO:0051783|regulation of nuclear division, ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,01291775 0,13259686 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01315403 0,13445729 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01315403 0,13389705 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01315403 0,13334146 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01315403 0,13279047 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01315403 0,132244 ! neuron fate determination GO:0048664 7 5 0,000 0,01315403 0,13170202 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01315403 0,13116446 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01315403 0,13063127 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01315403 0,1301024 ! polyol transport GO:0015791 12 5 0,000 0,01315403 0,12957779 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01315403 0,1290574 ! response to superoxide GO:0000303 10 5 0,000 0,01315403 0,12854117 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01315403 0,12802905 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01315403 0,127521 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01315403 0,12701697 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01315403 0,1265169 ! female meiosis GO:0007143 10 5 0,000 0,01315403 0,12602076 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01315403 0,12552849 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01315403 0,12504005 ! hypothalamus development GO:0021854 9 5 0,000 0,01315403 0,1245554 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01315403 0,12407449 ! cobalt ion transport GO:0006824 11 5 0,000 0,01315403 0,12359728 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01315403 0,12312373 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01315403 0,12265379 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01315403 0,12218742 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01315403 0,12172459 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01315403 0,12126525 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01315403 0,12080937 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01315403 0,1203569 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01315403 0,11990781 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01315403 0,11946205 ! transposition GO:0032196 9 5 0,000 0,01315403 0,1190196 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01315403 0,11858042 ! negative chemotaxis GO:0050919 16 5 0,000 0,01315403 0,11814446 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01315403 0,11771169 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01315403 0,11728209 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01315403 0,11685561 ! behavioral response to pain GO:0048266 10 5 0,000 0,01315403 0,11643222 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01315403 0,11601189 ! Notch receptor processing GO:0007220 11 5 0,000 0,01315403 0,11559458 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01315403 0,11518026 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01315403 0,1147689 ! micturition GO:0060073 9 5 0,000 0,01315403 0,11436047 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01315403 0,11395494 ! copulation GO:0007620 9 5 0,000 0,01315403 0,11355227 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01315403 0,11315244 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01315403 0,11275541 ! bioluminescence GO:0008218 9 5 0,000 0,01315403 0,11236116 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01315403 0,11196966 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01315403 0,11158088 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01315403 0,11119478 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01315403 0,11081135 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01315403 0,11043056 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01315403 0,11005237 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01315403 0,10967677 ! grooming behavior GO:0007625 6 5 0,000 0,01315403 0,10930372 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01315403 0,1089332 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01315403 0,10856518 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01315403 0,10819964 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01315403 0,10783655 ! response to protozoan GO:0001562 13 5 0,000 0,01315403 0,10747589 ! lymph vessel development GO:0001945 10 5 0,000 0,01315403 0,10711764 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01315403 0,10676177 ! endochondral ossification GO:0001958 17 5 0,000 0,01315403 0,10640825 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01315403 0,10605707 ! single strand break repair GO:0000012 8 5 0,000 0,01315403 0,1057082 ! parathyroid gland development GO:0060017 14 5 0,000 0,01315403 0,10536161 ! anagen GO:0042640 7 5 0,000 0,01315403 0,1050173 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01315403 0,10467522 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01315403 0,10433537 ! cytokine secretion GO:0050663 15 5 0,000 0,01315403 0,10399771 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01315403 0,10366223 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01315403 0,10332891 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01315403 0,10299773 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01315403 0,10266867 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01315403 0,1023417 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01315403 0,1020168 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01315403 0,10169396 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01315403 0,10137316 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01315403 0,10105438 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,01315403 0,10073759 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01315403 0,10042279 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01315403 0,10010995 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01315403 0,09979905 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01315403 0,09949007 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01315403 0,099183 ! microvillus organization GO:0032528 8 5 0,000 0,01315403 0,09887782 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01315403 0,09857452 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01315403 0,09827307 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01315403 0,09797345 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01315403 0,09767566 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01315403 0,09737967 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01315403 0,09708548 ! polyol catabolic process GO:0046174 9 5 0,000 0,01315403 0,09679305 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01315403 0,09650238 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01315403 0,09621345 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01315403 0,09592625 ! muscle cell migration GO:0014812 8 5 0,000 0,01315403 0,09564075 ! mitochondrial fission GO:0000266 8 5 0,000 0,01315403 0,09535695 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01315403 0,09507483 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01315403 0,09479437 ! mRNA transcription GO:0009299 10 5 0,000 0,01315403 0,09451557 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01315403 0,09423839 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01315403 0,09396284 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01315403 0,0936889 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01315403 0,09341655 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01315403 0,09314578 ! monocyte activation GO:0042117 10 5 0,000 0,01315403 0,09287657 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01315403 0,09260891 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01315403 0,09234279 ! response to food GO:0032094 6 5 0,000 0,01315403 0,0920782 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01315403 0,09181512 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01315403 0,09155354 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01315403 0,09129344 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01315403 0,09103482 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01315403 0,09077766 ! forebrain neuron development GO:0021884 13 5 0,000 0,01315403 0,09052195 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01315403 0,09026768 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01315403 0,09001483 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01315403 0,08976339 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01315403 0,08951335 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01315403 0,0892647 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01315403 0,08901743 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01315403 0,08877153 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01315403 0,08852698 ! lipid glycosylation GO:0030259 7 5 0,000 0,01315403 0,08828377 ! nucleobase transport GO:0015851 6 5 0,000 0,01315403 0,0880419 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01315403 0,08780135 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01315403 0,08756211 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01315403 0,08732416 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01315403 0,08708751 ! basic amino acid transport GO:0015802 12 5 0,000 0,01315403 0,08685214 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01315403 0,08661804 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01315403 0,0863852 ! actin nucleation GO:0045010 11 5 0,000 0,01315403 0,0861536 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01315403 0,08592324 ! depurination GO:0045007 5 5 0,000 0,01315403 0,08569411 ! depyrimidination GO:0045008 10 5 0,000 0,01315403 0,0854662 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01315403 0,0852395 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01315403 0,085014 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01315403 0,08478969 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01315403 0,08456656 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01315403 0,0843446 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01315403 0,0841238 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01315403 0,08390416 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01315403 0,08368566 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01315403 0,08346829 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01315403 0,08325205 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01315403 0,08303693 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01315403 0,08282292 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01315403 0,08261001 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01315403 0,08239819 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01315403 0,08218745 ! response to arsenic GO:0046685 11 5 0,000 0,01315403 0,08197779 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01315403 0,08176919 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01315403 0,08156166 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01315403 0,08135517 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01315403 0,08114973 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01315403 0,08094532 ! response to mercury ion GO:0046689 8 5 0,000 0,01315403 0,08074194 ! response to cadmium ion GO:0046686 7 5 0,000 0,01315403 0,08053958 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01315403 0,08033823 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01315403 0,08013789 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01315403 0,07993854 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01315403 0,07974018 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01315403 0,0795428 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01315403 0,0793464 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01315403 0,07915097 ! decidualization GO:0046697 11 5 0,000 0,01315403 0,07895649 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01315403 0,07876297 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01315403 0,0785704 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01315403 0,07837876 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01315403 0,07818806 ! embryonic cleavage GO:0040016 6 5 0,000 0,01315403 0,07799828 ! peroxisome fission GO:0016559 5 5 0,000 0,01315403 0,07780943 ! histone demethylation GO:0016577 13 5 0,000 0,01315403 0,07762148 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01315403 0,07743444 ! mitotic recombination GO:0006312 9 5 0,000 0,01315403 0,0772483 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01315403 0,07706305 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01315403 0,07687869 ! metaphase plate congression GO:0051310 7 5 0,000 0,01315403 0,07669521 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01315403 0,0765126 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01315403 0,07633086 ! enteric nervous system development GO:0048484 8 5 0,000 0,01315403 0,07614998 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01315403 0,07596996 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01315403 0,07579078 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01315403 0,07561245 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01315403 0,07543496 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01315403 0,0752583 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01315403 0,07508246 ! B cell homeostasis GO:0001782 13 5 0,000 0,01315403 0,07490744 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01315403 0,07473324 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01315403 0,07455984 ! metaphase GO:0051323 11 5 0,000 0,01315403 0,07438725 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01315403 0,07421546 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01315403 0,07404445 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01315403 0,07387424 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01315403 0,0737048 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01315403 0,07353614 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01315403 0,07336825 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01315403 0,07320112 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01315403 0,07303476 ! response to redox state GO:0051775 6 5 0,000 0,01315403 0,07286914 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01315403 0,07270428 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01315403 0,07254016 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01315403 0,07237679 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01315403 0,07221414 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01315403 0,07205223 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01315403 0,07189103 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01315403 0,07173056 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01315403 0,07157081 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01315403 0,07141176 ! striatum development GO:0021756 14 5 0,000 0,01315403 0,07125342 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01315403 0,07109578 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01315403 0,07093884 ! glial cell migration GO:0008347 10 5 0,000 0,01315403 0,07078258 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01315403 0,07062702 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01315403 0,07047213 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01315403 0,07031793 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01315403 0,07016439 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01315403 0,07001153 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01315403 0,06985933 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01315403 0,06970779 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01315403 0,06955691 ! neuroprotection GO:0043526 8 5 0,000 0,01315403 0,06940668 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01315403 0,0692571 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01315403 0,06910816 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01315403 0,06895986 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01315403 0,06881219 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01315403 0,06866516 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01315403 0,06851875 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01315403 0,06837296 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01315403 0,0682278 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01315403 0,06808325 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01315403 0,06793931 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01315403 0,06779598 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01315403 0,06765325 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01315403 0,06751112 ! spindle assembly GO:0051225 6 5 0,000 0,01315403 0,06736959 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01315403 0,06722865 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01315403 0,06708829 ! protein palmitoylation GO:0018345 12 5 0,000 0,01315403 0,06694853 ! drug metabolic process GO:0017144 7 5 0,000 0,01315403 0,06680934 ! stem cell division GO:0017145 11 5 0,000 0,01315403 0,06667073 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01315403 0,0665327 ! organ regeneration GO:0031100 7 5 0,000 0,01315403 0,06639523 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01315403 0,06625834 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01315403 0,066122 ! activation of MAPK activity GO:0000187 124 67 1,000 0,01368456 0,0686476 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,01368456 0,06850693 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,01407523 0,07031857 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! adaptive immune response GO:0002250 126 68 1,000 0,01407523 0,07017506 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,01407523 0,07003214 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,0144707 0,07185347 ! lung development GO:0030324 165 69 1,000 0,0144707 0,07170773 ! activation of immune response GO:0002253 120 70 1,000 0,01487094 0,07354191 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,01487094 0,07339334 ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01527593 0,07524012 ! respiratory tube development GO:0030323 171 72 1,000 0,01568564 0,07710267 ! B cell activation GO:0042113 179 72 1,000 0,01568564 0,07694784 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,01568564 0,07679364 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,01568564 0,07664005 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01576422 0,07687023 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01576422 0,0767171 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01576422 0,07656458 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01576422 0,07641267 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01576422 0,07626136 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01576422 0,07611064 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01576422 0,07596052 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01576422 0,07581099 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01576422 0,07566205 ! response to oxygen radical GO:0000305 11 6 0,000 0,01576422 0,0755137 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01576422 0,07536592 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01576422 0,07521872 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01576422 0,0750721 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01576422 0,07492604 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01576422 0,07478055 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01576422 0,07463563 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01576422 0,07449127 ! forebrain regionalization GO:0021871 9 6 0,000 0,01576422 0,07434746 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01576422 0,07420421 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01576422 0,07406151 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01576422 0,07391936 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01576422 0,07377775 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01576422 0,07363668 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01576422 0,07349616 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01576422 0,07335616 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01576422 0,0732167 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01576422 0,07307777 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01576422 0,07293937 ! malate metabolic process GO:0006108 13 6 0,000 0,01576422 0,07280148 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01576422 0,07266412 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01576422 0,07252728 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01576422 0,07239095 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01576422 0,07225513 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01576422 0,07211982 ! opsonization GO:0008228 8 6 0,000 0,01576422 0,07198502 ! mating behavior GO:0007617 7 6 0,000 0,01576422 0,07185072 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01576422 0,07171692 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01576422 0,07158362 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01576422 0,07145081 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01576422 0,07131849 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01576422 0,07118666 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01576422 0,07105532 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01576422 0,07092447 ! toxin metabolic process GO:0009404 11 6 0,000 0,01576422 0,07079409 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01576422 0,07066419 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01576422 0,07053477 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01576422 0,07040582 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,01576422 0,07027735 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01576422 0,07014934 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01576422 0,07002179 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01576422 0,06989471 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01576422 0,06976809 ! thymic T cell selection GO:0045061 16 6 0,000 0,01576422 0,06964193 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01576422 0,06951622 ! protein lipoylation GO:0009249 10 6 0,000 0,01576422 0,06939096 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01576422 0,06926616 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01576422 0,0691418 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01576422 0,06901789 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01576422 0,06889443 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01576422 0,0687714 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01576422 0,06864882 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01576422 0,06852666 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01576422 0,06840495 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01576422 0,06828366 ! hyperosmotic response GO:0006972 10 6 0,000 0,01576422 0,06816281 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01576422 0,06804238 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01576422 0,06792237 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01576422 0,06780279 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01576422 0,06768363 ! urea metabolic process GO:0019627 7 6 0,000 0,01576422 0,06756489 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01576422 0,06744656 ! neutrophil activation GO:0042119 7 6 0,000 0,01576422 0,06732865 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01576422 0,06721114 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01576422 0,06709405 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01576422 0,06697737 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01576422 0,06686109 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01576422 0,06674521 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01576422 0,06662973 ! neuron apoptosis GO:0051402 15 6 0,000 0,01576422 0,06651466 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01576422 0,06639997 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01576422 0,06628569 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01576422 0,0661718 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01576422 0,06605829 ! carnitine transport GO:0015879 10 6 0,000 0,01576422 0,06594518 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01576422 0,06583245 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01576422 0,06572011 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01576422 0,06560815 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,01576422 0,06549657 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01576422 0,06538537 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01576422 0,06527455 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01576422 0,0651641 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01576422 0,06505403 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01576422 0,06494433 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01576422 0,06483499 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01576422 0,06472603 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01576422 0,06461742 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01576422 0,06450919 ! response to UV-C GO:0010225 14 6 0,000 0,01576422 0,06440131 ! astrocyte development GO:0014002 16 6 0,000 0,01576422 0,0642938 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01576422 0,06418664 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01576422 0,06407984 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01576422 0,0639734 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01576422 0,06386731 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01576422 0,06376157 ! response to copper ion GO:0046688 10 6 0,000 0,01576422 0,06365617 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01576422 0,06355113 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01576422 0,06344643 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01576422 0,06334208 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01576422 0,06323807 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01576422 0,0631344 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01576422 0,06303107 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01576422 0,06292808 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01576422 0,06282542 ! hair follicle maturation GO:0048820 8 6 0,000 0,01576422 0,0627231 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01576422 0,06262111 ! Schwann cell development GO:0014044 15 6 0,000 0,01576422 0,06251946 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01576422 0,06241813 ! response to pheromone GO:0019236 6 6 0,000 0,01576422 0,06231713 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01576422 0,06221645 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01576422 0,06211611 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01576422 0,06201608 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01576422 0,06191638 ! subpallium development GO:0021544 15 6 0,000 0,01576422 0,06181699 ! neural tube patterning GO:0021532 8 6 0,000 0,01576422 0,06171793 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01576422 0,06161918 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01576422 0,06152074 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01576422 0,06142262 ! G2 phase GO:0051319 16 6 0,000 0,01576422 0,06132482 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01576422 0,06122732 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01576422 0,06113014 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01576422 0,06103326 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01576422 0,06093669 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01576422 0,06084042 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01576422 0,06074446 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01576422 0,0606488 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01576422 0,06055344 ! receptor internalization GO:0031623 11 6 0,000 0,01576422 0,06045838 ! plasminogen activation GO:0031639 9 6 0,000 0,01576422 0,06036361 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01576422 0,06026915 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01576422 0,06017498 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01576422 0,0600811 ! protein deubiquitination GO:0016579 16 6 0,000 0,01576422 0,05998752 ! protein destabilization GO:0031648 9 6 0,000 0,01576422 0,05989422 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01576422 0,05980122 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01576422 0,0597085 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01576422 0,05961608 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01576422 0,05952393 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01576422 0,05943208 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01576422 0,0593405 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01576422 0,05924921 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01576422 0,0591582 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01576422 0,05906746 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01576422 0,05897701 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01576422 0,05888683 ! neural plate development GO:0001840 9 6 0,000 0,01576422 0,05879692 ! catecholamine transport GO:0051937 9 6 0,000 0,01576422 0,05870729 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01576422 0,05861794 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01576422 0,05852885 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01576422 0,05844004 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01576422 0,05835149 ! maternal placenta development GO:0001893 12 6 0,000 0,01576422 0,05826322 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01576422 0,0581752 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01576422 0,05808746 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01576422 0,05799998 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01576422 0,05791276 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01576422 0,0578258 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01576422 0,05773911 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01576422 0,05765267 GO:0055081|anion homeostasis, ! humoral immune response GO:0006959 115 73 1,000 0,01610005 0,05879285 ! acute inflammatory response GO:0002526 118 74 1,000 0,01651912 0,06023314 ! respiratory system development GO:0060541 175 74 1,000 0,01651912 0,06014338 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01694283 0,06159424 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,01694283 0,06150272 ! learning or memory GO:0007611 161 76 1,000 0,01737115 0,06296397 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,01737115 0,06287069 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,01780406 0,06434217 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,01780406 0,06424713 ! regulation of catabolic process GO:0009894 173 77 1,000 0,01780406 0,06415237 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,01824152 0,06563186 ! tRNA transcription GO:0009304 17 7 0,000 0,01836758 0,06598822 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01836758 0,06589132 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01836758 0,06579471 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01836758 0,06569838 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01836758 0,06560233 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01836758 0,06550656 ! sleep GO:0030431 16 7 0,000 0,01836758 0,06541107 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01836758 0,06531585 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01836758 0,06522092 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01836758 0,06512626 ! prostate gland development GO:0030850 14 7 0,000 0,01836758 0,06503187 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01836758 0,06493776 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01836758 0,06484392 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01836758 0,06475035 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01836758 0,06465705 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01836758 0,06456402 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01836758 0,06447125 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01836758 0,06437875 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01836758 0,06428652 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01836758 0,06419455 ! glycolipid transport GO:0046836 11 7 0,000 0,01836758 0,06410284 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01836758 0,0640114 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01836758 0,06392021 ! neuron adhesion GO:0007158 14 7 0,000 0,01836758 0,06382929 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01836758 0,06373862 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01836758 0,06364821 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01836758 0,06355806 ! mRNA stabilization GO:0048255 18 7 0,000 0,01836758 0,06346816 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,01836758 0,06337852 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01836758 0,06328913 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01836758 0,06319999 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01836758 0,0631111 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01836758 0,06302246 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01836758 0,06293407 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01836758 0,06284593 ! lipoprotein transport GO:0042953 14 7 0,000 0,01836758 0,06275803 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01836758 0,06267038 ! rhythmic behavior GO:0007622 17 7 0,000 0,01836758 0,06258297 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01836758 0,06249581 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01836758 0,06240889 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01836758 0,06232221 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01836758 0,06223577 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01836758 0,06214957 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01836758 0,06206361 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01836758 0,06197789 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01836758 0,0618924 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01836758 0,06180715 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01836758 0,06172213 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01836758 0,06163735 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01836758 0,0615528 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01836758 0,06146848 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01836758 0,06138439 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01836758 0,06130053 ! spinal cord patterning GO:0021511 14 7 0,000 0,01836758 0,0612169 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01836758 0,0611335 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01836758 0,06105033 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01836758 0,06096738 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01836758 0,06088465 ! adrenal gland development GO:0030325 17 7 0,000 0,01836758 0,06080216 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01836758 0,06071988 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01836758 0,06063783 ! ovulation GO:0030728 10 7 0,000 0,01836758 0,06055599 ! adenohypophysis development GO:0021984 11 7 0,000 0,01836758 0,06047438 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01836758 0,06039299 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01836758 0,06031182 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01836758 0,06023086 ! microtubule nucleation GO:0007020 21 7 0,000 0,01836758 0,06015012 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01836758 0,0600696 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01836758 0,05998929 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01836758 0,0599092 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01836758 0,05982932 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01836758 0,05974965 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01836758 0,0596702 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01836758 0,05959096 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01836758 0,05951192 ! galactose metabolic process GO:0006012 13 7 0,000 0,01836758 0,0594331 ! vesicle fusion GO:0006906 20 7 0,000 0,01836758 0,05935449 ! response to dietary excess GO:0002021 8 7 0,000 0,01836758 0,05927608 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01836758 0,05919788 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01836758 0,05911988 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01836758 0,05904209 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01836758 0,05896451 ! organ growth GO:0035265 15 7 0,000 0,01836758 0,05888713 ! nucleoside transport GO:0015858 11 7 0,000 0,01836758 0,05880995 ! nucleoside salvage GO:0043174 11 7 0,000 0,01836758 0,05873297 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01836758 0,0586562 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01836758 0,05857962 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01836758 0,05850325 ! parturition GO:0007567 16 7 0,000 0,01836758 0,05842707 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01836758 0,05835109 ! rRNA modification GO:0000154 14 7 0,000 0,01836758 0,05827531 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01836758 0,05819973 ! spindle checkpoint GO:0031577 16 7 0,000 0,01836758 0,05812434 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01836758 0,05804915 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01836758 0,05797415 ! monocyte differentiation GO:0030224 16 7 0,000 0,01836758 0,05789934 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01836758 0,05782473 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01836758 0,05775031 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01836758 0,05767608 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01836758 0,05760204 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01836758 0,05752819 ! fibrinolysis GO:0042730 11 7 0,000 0,01836758 0,05745453 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,01836758 0,05738106 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01836758 0,05730778 ! eating behavior GO:0042755 8 7 0,000 0,01836758 0,05723468 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01836758 0,05716177 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01836758 0,05708905 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01836758 0,05701651 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01836758 0,05694415 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01836758 0,05687198 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01836758 0,05679999 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01836758 0,05672818 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01836758 0,05665655 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01836758 0,05658511 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01836758 0,05651384 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01836758 0,05644276 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01836758 0,05637185 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01836758 0,05630112 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01836758 0,05623056 ! histone ubiquitination GO:0016574 9 7 0,000 0,01836758 0,05616019 ! regulation of meiosis GO:0040020 12 7 0,000 0,01836758 0,05608999 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01836758 0,05601996 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01836758 0,05595011 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01836758 0,05588044 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01836758 0,05581093 ! transcription termination GO:0006353 14 7 0,000 0,01836758 0,0557416 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01836758 0,05567245 ! anaphase GO:0051322 18 7 0,000 0,01836758 0,05560346 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01836758 0,05553464 ! axonal fasciculation GO:0007413 19 7 0,000 0,01836758 0,055466 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,01836758 0,05539752 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01836758 0,05532921 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01836758 0,05526107 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01836758 0,0551931 ! diuresis GO:0030146 12 7 0,000 0,01836758 0,0551253 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01836758 0,05505766 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01836758 0,05499018 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01836758 0,05492288 ! antibiotic transport GO:0042891 9 7 0,000 0,01836758 0,05485573 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01836758 0,05478876 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01836758 0,05472194 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01836758 0,05465529 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01836758 0,0545888 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01836758 0,05452247 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01836758 0,0544563 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01836758 0,05439029 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01836758 0,05432444 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01836758 0,05425876 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01836758 0,05419323 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01836758 0,05412785 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01836758 0,05406264 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01836758 0,05399758 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01836758 0,05393268 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01836758 0,05386794 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01836758 0,05380335 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01836758 0,05373891 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01836758 0,05367463 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01836758 0,0536105 ! muscle adaptation GO:0043500 13 7 0,000 0,01836758 0,05354653 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01836758 0,05348271 ! retina homeostasis GO:0001895 12 7 0,000 0,01836758 0,05341904 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01836758 0,05335552 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01836758 0,05329215 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01836758 0,05322893 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01836758 0,05316587 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,01868352 0,05401637 ! response to hypoxia GO:0001666 178 81 1,000 0,019581 0,05654419 ! protein import into nucleus GO:0006606 174 82 1,000 0,02003643 0,05779104 ! response to drug GO:0042493 149 83 1,000 0,02049629 0,0590477 ! response to oxygen levels GO:0070482 183 83 1,000 0,02049629 0,05897815 ! nuclear import GO:0051170 177 83 1,000 0,02049629 0,05890876 ! T cell activation GO:0042110 189 84 1,000 0,02096056 0,06017231 ! regulation of ligase activity GO:0051340 147 84 1,000 0,02096056 0,06010169 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02096412 0,06004144 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02096412 0,05997114 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,02096412 0,059901 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02096412 0,05983102 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02096412 0,0597612 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02096412 0,05969155 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02096412 0,05962206 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02096412 0,05955273 ! male meiosis GO:0007140 9 8 0,000 0,02096412 0,05948357 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02096412 0,05941456 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02096412 0,05934572 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02096412 0,05927703 ! meiotic prophase I GO:0007128 14 8 0,000 0,02096412 0,0592085 ! response to zinc ion GO:0010043 12 8 0,000 0,02096412 0,05914013 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02096412 0,05907192 ! oligopeptide transport GO:0006857 16 8 0,000 0,02096412 0,05900386 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02096412 0,05893596 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02096412 0,05886822 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02096412 0,05880063 ! signal peptide processing GO:0006465 12 8 0,000 0,02096412 0,0587332 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02096412 0,05866592 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02096412 0,0585988 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02096412 0,05853183 ! succinate metabolic process GO:0006105 17 8 0,000 0,02096412 0,05846501 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02096412 0,05839835 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02096412 0,05833184 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02096412 0,05826547 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02096412 0,05819926 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02096412 0,0581332 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02096412 0,05806729 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02096412 0,05800153 GO:0032107|regulation of response to nutrient levels, ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02096412 0,05793592 ! reflex GO:0060004 17 8 0,000 0,02096412 0,05787045 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02096412 0,05780514 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02096412 0,05773997 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02096412 0,05767495 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02096412 0,05761007 ! pigment granule organization GO:0048753 17 8 0,000 0,02096412 0,05754534 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02096412 0,05748075 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02096412 0,05741631 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02096412 0,05735202 ! histidine catabolic process GO:0006548 10 8 0,000 0,02096412 0,05728787 GO:0009077|histidine family amino acid catabolic process, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02096412 0,05722386 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02096412 0,05715999 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02096412 0,05709627 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02096412 0,05703269 ! melanin metabolic process GO:0006582 17 8 0,000 0,02096412 0,05696925 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02096412 0,05690595 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02096412 0,05684279 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02096412 0,05677977 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02096412 0,05671689 ! macrophage activation GO:0042116 13 8 0,000 0,02096412 0,05665415 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02096412 0,05659155 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02096412 0,05652909 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02096412 0,05646676 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02096412 0,05640457 ! purine salvage GO:0043101 12 8 0,000 0,02096412 0,05634252 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02096412 0,05628061 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02096412 0,05621883 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02096412 0,05615718 ! osteoblast development GO:0002076 17 8 0,000 0,02096412 0,05609568 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02096412 0,0560343 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02096412 0,05597306 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02096412 0,05591196 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02096412 0,05585098 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02096412 0,05579014 ! response to UV-B GO:0010224 17 8 0,000 0,02096412 0,05572944 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02096412 0,05566886 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02096412 0,05560842 ! intermediate filament organization GO:0045109 12 8 0,000 0,02096412 0,0555481 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02096412 0,05548792 ! cellular extravasation GO:0045123 13 8 0,000 0,02096412 0,05542787 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02096412 0,05536795 ! response to antibiotic GO:0046677 11 8 0,000 0,02096412 0,05530816 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02096412 0,05524849 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02096412 0,05518896 ! DNA topological change GO:0006265 12 8 0,000 0,02096412 0,05512955 ! response to tropane GO:0014073 15 8 0,000 0,02096412 0,05507027 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02096412 0,05501112 ! melanosome transport GO:0032402 13 8 0,000 0,02096412 0,05495209 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02096412 0,0548932 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02096412 0,05483442 ! mast cell activation GO:0045576 14 8 0,000 0,02096412 0,05477578 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02096412 0,05471726 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02096412 0,05465886 ! gas homeostasis GO:0033483 14 8 0,000 0,02096412 0,05460059 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02096412 0,05454244 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02096412 0,05448442 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02096412 0,05442652 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02096412 0,05436874 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02096412 0,05431108 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02096412 0,05425355 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02096412 0,05419614 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02096412 0,05413885 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02096412 0,05408168 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02096412 0,05402463 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02096412 0,05396771 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02096412 0,0539109 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02096412 0,05385421 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02096412 0,05379764 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02096412 0,05374119 ! hormone catabolic process GO:0042447 17 8 0,000 0,02096412 0,05368486 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02096412 0,05362864 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02096412 0,05357254 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02096412 0,05351656 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02096412 0,0534607 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02096412 0,05340496 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02096412 0,05334933 ! adult feeding behavior GO:0008343 10 8 0,000 0,02096412 0,05329381 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02096412 0,05323841 ! ATP catabolic process GO:0006200 11 8 0,000 0,02096412 0,05318313 ! blastocyst growth GO:0001832 19 8 0,000 0,02096412 0,05312796 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02096412 0,0530729 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02096412 0,05301796 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02096412 0,05296314 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02096412 0,05290842 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02096412 0,05285382 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02096412 0,05279933 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02096412 0,05274496 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02096412 0,05269069 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02096412 0,05263654 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02096412 0,0525825 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02096412 0,05252857 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02096412 0,05247475 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02096412 0,05242104 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02096412 0,05236744 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02096412 0,05231394 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02096412 0,05226056 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02096412 0,05220729 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02096412 0,05215413 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02096412 0,05210107 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02096412 0,05204812 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,02190217 0,05432184 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,02237948 0,05544936 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,02286109 0,05658524 ! protein localization in nucleus GO:0034504 192 89 1,000 0,02334696 0,05772938 ! axon extension GO:0048675 16 9 0,000 0,02355387 0,05818212 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,02355387 0,05812335 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,02355387 0,05806469 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02355387 0,05800616 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,02355387 0,05794775 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,02355387 0,05788945 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,02355387 0,05783127 ! reproductive behavior GO:0019098 22 9 0,000 0,02355387 0,05777321 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02355387 0,05771526 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,02355387 0,05765743 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,02355387 0,05759971 ! UTP metabolic process GO:0046051 10 9 0,000 0,02355387 0,05754211 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,02355387 0,05748463 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,02355387 0,05742726 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,02355387 0,05737 ! artery development GO:0060840 25 9 0,000 0,02355387 0,05731286 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,02355387 0,05725583 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,02355387 0,05719892 ! equilibrioception GO:0050957 20 9 0,000 0,02355387 0,05714212 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,02355387 0,05708543 ! chemosensory behavior GO:0007635 21 9 0,000 0,02355387 0,05702885 ! microtubule bundle formation GO:0001578 22 9 0,000 0,02355387 0,05697239 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02355387 0,05691604 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,02355387 0,05685979 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02355387 0,05680366 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,02355387 0,05674765 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,02355387 0,05669174 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,02355387 0,05663594 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,02355387 0,05658025 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02355387 0,05652467 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02355387 0,0564692 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,02355387 0,05641384 ! protein targeting to ER GO:0045047 25 9 0,000 0,02355387 0,05635858 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,02355387 0,05630344 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,02355387 0,0562484 ! T cell selection GO:0045058 27 9 0,000 0,02355387 0,05619347 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,02355387 0,05613865 ! glycine catabolic process GO:0006546 15 9 0,000 0,02355387 0,05608393 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,02355387 0,05602932 ! endosome organization GO:0007032 20 9 0,000 0,02355387 0,05597482 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02355387 0,05592042 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,02355387 0,05586613 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02355387 0,05581194 ! mannose metabolic process GO:0006013 13 9 0,000 0,02355387 0,05575786 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,02355387 0,05570388 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,02355387 0,05565001 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,02355387 0,05559624 ! receptor clustering GO:0043113 20 9 0,000 0,02355387 0,05554258 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,02355387 0,05548902 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02355387 0,05543556 ! retinol metabolic process GO:0042572 20 9 0,000 0,02355387 0,05538221 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,02355387 0,05532895 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,02355387 0,0552758 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,02355387 0,05522276 ! oligodendrocyte development GO:0014003 11 9 0,000 0,02355387 0,05516981 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,02355387 0,05511697 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02355387 0,05506422 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,02355387 0,05501158 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02355387 0,05495904 ! response to amine stimulus GO:0014075 13 9 0,000 0,02355387 0,0549066 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02355387 0,05485425 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,02355387 0,05480201 ! erythrocyte development GO:0048821 17 9 0,000 0,02355387 0,05474987 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02355387 0,05469783 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,02355387 0,05464588 ! renal water homeostasis GO:0003091 15 9 0,000 0,02355387 0,05459403 ! postreplication repair GO:0006301 25 9 0,000 0,02355387 0,05454229 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,02355387 0,05449064 ! icosanoid secretion GO:0032309 15 9 0,000 0,02355387 0,05443908 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02355387 0,05438763 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,02355387 0,05433627 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,02355387 0,05428501 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,02355387 0,05423385 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02355387 0,05418278 ! sterol catabolic process GO:0016127 14 9 0,000 0,02355387 0,05413181 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02355387 0,05408093 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,02355387 0,05403015 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,02355387 0,05397947 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,02355387 0,05392888 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,02355387 0,05387838 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,02355387 0,05382798 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,02355387 0,05377768 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,02355387 0,05372746 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,02355387 0,05367734 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,02355387 0,05362732 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02355387 0,05357739 ! purine base metabolic process GO:0006144 25 9 0,000 0,02355387 0,05352755 ! pigment granule transport GO:0051904 17 9 0,000 0,02355387 0,0534778 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,02355387 0,05342815 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,02355387 0,05337858 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,02355387 0,05332911 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02355387 0,05327973 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,02355387 0,05323045 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,02355387 0,05318125 ! mitochondrion localization GO:0051646 18 9 0,000 0,02355387 0,05313214 ! response to unfolded protein GO:0006986 139 90 1,000 0,02383708 0,0537214 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,02383708 0,05367188 ! gland development GO:0048732 220 91 1,000 0,02433143 0,0547345 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,02482996 0,0558046 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,02533267 0,05688209 GO:0010498|proteasomal protein catabolic process, ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,02533267 0,05682986 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02613685 0,05858011 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02613685 0,05852641 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02613685 0,05847282 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02613685 0,05841932 ! associative learning GO:0008306 21 10 0,000 0,02613685 0,05836592 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02613685 0,05831262 ! phosphate transport GO:0006817 24 10 0,000 0,02613685 0,05825941 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02613685 0,0582063 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02613685 0,05815329 ! CTP metabolic process GO:0046036 11 10 0,000 0,02613685 0,05810038 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02613685 0,05804756 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02613685 0,05799484 ! GTP metabolic process GO:0046039 11 10 0,000 0,02613685 0,05794221 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02613685 0,05788968 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02613685 0,05783724 ! social behavior GO:0035176 29 10 0,000 0,02613685 0,0577849 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02613685 0,05773265 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02613685 0,0576805 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02613685 0,05762844 ! androgen metabolic process GO:0008209 17 10 0,000 0,02613685 0,05757648 ! phospholipid efflux GO:0033700 19 10 0,000 0,02613685 0,05752461 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02613685 0,05747283 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02613685 0,05742115 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02613685 0,05736956 ! lung alveolus development GO:0048286 26 10 0,000 0,02613685 0,05731806 ! pathogenesis GO:0009405 17 10 0,000 0,02613685 0,05726665 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02613685 0,05721534 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02613685 0,05716411 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02613685 0,05711298 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02613685 0,05706194 ! endoderm development GO:0007492 18 10 0,000 0,02613685 0,057011 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02613685 0,05696014 ! arginine catabolic process GO:0006527 17 10 0,000 0,02613685 0,05690937 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02613685 0,0568587 ! proline metabolic process GO:0006560 13 10 0,000 0,02613685 0,05680811 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02613685 0,05675761 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02613685 0,05670721 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02613685 0,05665689 ! V(D)J recombination GO:0033151 34 10 0,000 0,02613685 0,05660666 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02613685 0,05655652 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02613685 0,05650647 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02613685 0,05645651 ! B cell proliferation GO:0042100 19 10 0,000 0,02613685 0,05640664 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02613685 0,05635685 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02613685 0,05630716 ! multicellular organism growth GO:0035264 19 10 0,000 0,02613685 0,05625755 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02613685 0,05620802 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02613685 0,05615859 ! ruffle organization GO:0031529 17 10 0,000 0,02613685 0,05610924 ! epithelial cell development GO:0002064 21 10 0,000 0,02613685 0,05605998 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02613685 0,0560108 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02613685 0,05596171 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02613685 0,05591271 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02613685 0,05586379 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02613685 0,05581496 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02613685 0,05576621 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,02613685 0,05571755 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02613685 0,05566898 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02613685 0,05562048 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02613685 0,05557208 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02613685 0,05552375 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02613685 0,05547551 ! segment specification GO:0007379 15 10 0,000 0,02613685 0,05542736 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02613685 0,05537928 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,02613685 0,0553313 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02613685 0,05528339 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02613685 0,05523557 ! response to dsRNA GO:0043331 23 10 0,000 0,02613685 0,05518783 ! DNA ligation GO:0006266 18 10 0,000 0,02613685 0,05514017 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02613685 0,05509259 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02613685 0,0550451 ! melanosome localization GO:0032400 16 10 0,000 0,02613685 0,05499769 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02613685 0,05495036 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02613685 0,05490311 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02613685 0,05485594 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02613685 0,05480885 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02613685 0,05476185 ! induction of an organ GO:0001759 17 10 0,000 0,02613685 0,05471492 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02613685 0,05466808 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02613685 0,05462131 ! protein sumoylation GO:0016925 17 10 0,000 0,02613685 0,05457463 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02613685 0,05452802 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02613685 0,0544815 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02613685 0,05443505 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02613685 0,05438868 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02613685 0,0543424 ! salivary gland development GO:0007431 28 10 0,000 0,02613685 0,05429619 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02613685 0,05425006 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02613685 0,054204 ! midbrain development GO:0030901 14 10 0,000 0,02613685 0,05415803 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02613685 0,05411213 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02613685 0,05406631 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02613685 0,05402057 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02613685 0,05397491 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02613685 0,05392932 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02613685 0,05388381 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02613685 0,05383838 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02613685 0,05379302 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02613685 0,05374774 ! detection of calcium ion GO:0005513 24 10 0,000 0,02613685 0,05370254 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02613685 0,05365741 ! blastocyst formation GO:0001825 18 10 0,000 0,02613685 0,05361236 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02613685 0,05356738 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02613685 0,05352248 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02613685 0,05347765 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02613685 0,0534329 ! response to nicotine GO:0035094 20 10 0,000 0,02613685 0,05338822 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02613685 0,05334362 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02613685 0,05329909 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,0263505 0,05368997 ! response to protein stimulus GO:0051789 158 96 1,000 0,02686557 0,05469383 ! regulation of protein localization GO:0032880 188 97 1,000 0,02738471 0,05570429 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,02871306 0,05835774 ! respiratory burst GO:0045730 17 11 0,000 0,02871306 0,05830923 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,02871306 0,0582608 ! neuron fate specification GO:0048665 18 11 0,000 0,02871306 0,05821245 ! telencephalon cell migration GO:0022029 23 11 0,000 0,02871306 0,05816418 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,02871306 0,05811599 ! thyroid gland development GO:0030878 26 11 0,000 0,02871306 0,05806788 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,02871306 0,05801985 ! synapsis GO:0007129 14 11 0,000 0,02871306 0,0579719 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,02871306 0,05792403 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,02871306 0,05787624 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,02871306 0,05782853 ! response to pain GO:0048265 27 11 0,000 0,02871306 0,05778089 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02871306 0,05773334 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,02871306 0,05768586 ! blood vessel remodeling GO:0001974 30 11 0,000 0,02871306 0,05763846 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,02871306 0,05759113 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,02871306 0,05754389 ! bone resorption GO:0045453 16 11 0,000 0,02871306 0,05749672 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,02871306 0,05744963 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02871306 0,05740262 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02871306 0,05735568 ! melanocyte differentiation GO:0030318 20 11 0,000 0,02871306 0,05730883 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,02871306 0,05726204 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,02871306 0,05721534 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,02871306 0,05716871 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,02871306 0,05712215 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,02871306 0,05707567 ! UV protection GO:0009650 20 11 0,000 0,02871306 0,05702927 ! adult heart development GO:0007512 16 11 0,000 0,02871306 0,05698294 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,02871306 0,05693669 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02871306 0,05689051 ! macroautophagy GO:0016236 19 11 0,000 0,02871306 0,05684441 ! temperature homeostasis GO:0001659 18 11 0,000 0,02871306 0,05679838 ! behavioral fear response GO:0001662 27 11 0,000 0,02871306 0,05675243 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,02871306 0,05670655 ! negative regulation of ossification GO:0030279 27 11 0,000 0,02871306 0,05666074 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,02871306 0,05661501 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,02871306 0,05656936 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,02871306 0,05652377 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,02871306 0,05647826 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,02871306 0,05643283 ! regulation of organ growth GO:0046620 14 11 0,000 0,02871306 0,05638746 ! pigment granule localization GO:0051875 20 11 0,000 0,02871306 0,05634217 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,02871306 0,05629695 ! vasoconstriction GO:0042310 20 11 0,000 0,02871306 0,05625181 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,02871306 0,05620673 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02871306 0,05616173 ! embryonic axis specification GO:0000578 19 11 0,000 0,02871306 0,0561168 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,02871306 0,05607194 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02871306 0,05602716 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,02871306 0,05598244 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,02871306 0,0559378 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02871306 0,05589323 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,02871306 0,05584873 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,02871306 0,0558043 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,02871306 0,05575994 ! prophase GO:0051324 17 11 0,000 0,02871306 0,05571565 ! neuroblast proliferation GO:0007405 25 11 0,000 0,02871306 0,05567143 ! nucleosome positioning GO:0016584 15 11 0,000 0,02871306 0,05562728 ! regulation of isotype switching GO:0045191 24 11 0,000 0,02871306 0,0555832 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,02871306 0,05553919 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,02871306 0,05549525 ! apical protein localization GO:0045176 18 11 0,000 0,02871306 0,05545139 ! acid secretion GO:0046717 20 11 0,000 0,02871306 0,05540758 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02871306 0,05536385 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,02871306 0,05532019 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,02871306 0,0552766 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,02871306 0,05523307 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,02871306 0,05518962 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,02871306 0,05514623 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,02871306 0,05510291 ! cholesterol efflux GO:0033344 21 11 0,000 0,02871306 0,05505966 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02871306 0,05501647 ! oocyte development GO:0048599 20 11 0,000 0,02871306 0,05497336 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,02871306 0,05493031 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,02871306 0,05488733 ! embryonic gut development GO:0048566 19 11 0,000 0,02871306 0,05484441 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,02871306 0,05480156 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,02871306 0,05475878 ! activation of innate immune response GO:0002218 16 11 0,000 0,02871306 0,05471607 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,02871306 0,05467342 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,02871306 0,05463084 ! lysogeny GO:0030069 22 11 0,000 0,02871306 0,05458833 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02871306 0,05454588 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,02871306 0,0545035 ! sequestering of metal ion GO:0051238 15 11 0,000 0,02871306 0,05446118 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,02896632 0,05489892 GO:0060538|skeletal muscle organ development, ! positive regulation of immune response GO:0050778 175 100 1,000 0,02896632 0,05485637 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03128253 0,05919691 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03128253 0,0591511 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03128253 0,05910535 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,03128253 0,05905967 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03128253 0,05901407 ! protein complex disassembly GO:0043241 28 12 0,000 0,03128253 0,05896853 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03128253 0,05892307 ! hippocampus development GO:0021766 29 12 0,000 0,03128253 0,05887767 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03128253 0,05883235 ! T cell proliferation GO:0042098 32 12 0,000 0,03128253 0,05878709 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03128253 0,0587419 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03128253 0,05869679 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03128253 0,05865174 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03128253 0,05860676 ! drug transport GO:0015893 16 12 0,000 0,03128253 0,05856185 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03128253 0,05851701 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03128253 0,05847224 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03128253 0,05842754 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03128253 0,0583829 ! focal adhesion formation GO:0048041 37 12 0,000 0,03128253 0,05833833 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03128253 0,05829383 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03128253 0,0582494 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03128253 0,05820504 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03128253 0,05816074 ! lipid digestion GO:0044241 21 12 0,000 0,03128253 0,05811651 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03128253 0,05807235 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03128253 0,05802826 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03128253 0,05798423 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03128253 0,05794027 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03128253 0,05789638 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03128253 0,05785255 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03128253 0,05780879 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03128253 0,05776509 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03128253 0,05772146 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03128253 0,0576779 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03128253 0,0576344 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03128253 0,05759097 ! cranial nerve development GO:0021545 23 12 0,000 0,03128253 0,0575476 ! fucose catabolic process GO:0019317 25 12 0,000 0,03128253 0,0575043 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03128253 0,05746107 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03128253 0,05741789 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03128253 0,05737479 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,03128253 0,05733175 ! zymogen activation GO:0031638 18 12 0,000 0,03128253 0,05728877 ! T cell homeostasis GO:0043029 28 12 0,000 0,03128253 0,05724586 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03128253 0,05720301 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03128253 0,05716022 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,03128253 0,0571175 ! oocyte differentiation GO:0009994 21 12 0,000 0,03128253 0,05707484 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03128253 0,05703225 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03128253 0,05698972 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,03128253 0,05694726 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,03128253 0,05690485 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03128253 0,05686251 ! defense response to fungus GO:0050832 15 12 0,000 0,03128253 0,05682024 ! developmental induction GO:0031128 22 12 0,000 0,03128253 0,05677802 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,03128253 0,05673587 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03128253 0,05669378 ! response to cold GO:0009409 17 12 0,000 0,03128253 0,05665175 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03128253 0,05660979 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03128253 0,05656789 ! localization within membrane GO:0051668 26 12 0,000 0,03128253 0,05652605 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03384527 0,06111161 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03384527 0,06106647 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03384527 0,0610214 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03384527 0,0609764 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03384527 0,06093147 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03384527 0,0608866 ! peroxisomal transport GO:0043574 28 13 0,000 0,03384527 0,0608418 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03384527 0,06079706 ! cartilage condensation GO:0001502 22 13 0,000 0,03384527 0,06075239 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03384527 0,06070778 ! organelle fusion GO:0048284 36 13 0,000 0,03384527 0,06066324 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03384527 0,06061877 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03384527 0,06057436 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03384527 0,06053002 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03384527 0,06048574 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03384527 0,06044152 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03384527 0,06039737 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03384527 0,06035329 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03384527 0,06030926 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03384527 0,06026531 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03384527 0,06022141 ! methionine metabolic process GO:0006555 31 13 0,000 0,03384527 0,06017759 ! plasma membrane organization GO:0007009 27 13 0,000 0,03384527 0,06013382 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03384527 0,06009012 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03384527 0,06004648 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03384527 0,0600029 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03384527 0,05995939 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,03384527 0,05991594 ! exocrine system development GO:0035272 34 13 0,000 0,03384527 0,05987256 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03384527 0,05982923 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03384527 0,05978597 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03384527 0,05974278 ! L-glutamate transport GO:0015813 30 13 0,000 0,03384527 0,05969964 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03384527 0,05965657 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03384527 0,05961356 ! protein homotetramerization GO:0051289 24 13 0,000 0,03384527 0,05957061 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03384527 0,05952772 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03384527 0,05948489 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03384527 0,05944213 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03384527 0,05939943 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03384527 0,05935679 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03384527 0,05931421 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,03384527 0,05927169 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03384527 0,05922923 ! histone methylation GO:0016571 29 13 0,000 0,03384527 0,05918683 ! chromatin silencing GO:0006342 29 13 0,000 0,03384527 0,05914449 ! gland morphogenesis GO:0022612 31 13 0,000 0,03384527 0,05910222 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03384527 0,05906 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03384527 0,05901785 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03384527 0,05897575 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03384527 0,05893371 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03384527 0,05889174 ! spleen development GO:0048536 24 13 0,000 0,03384527 0,05884982 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,03384527 0,05880797 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03384527 0,05876617 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03384527 0,05872443 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03384527 0,05868276 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03384527 0,05864114 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03384527 0,05859958 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03384527 0,05855808 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03384527 0,05851663 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03384527 0,05847525 ! insulin secretion GO:0030073 24 13 0,000 0,03384527 0,05843392 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03384527 0,05839266 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,03384527 0,05835145 ! acrosome reaction GO:0007340 19 13 0,000 0,03384527 0,0583103 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03384527 0,05826921 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03384527 0,05822817 ! rRNA transcription GO:0009303 28 14 0,000 0,03640131 0,06258156 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03640131 0,06253755 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03640131 0,06249361 ! water transport GO:0006833 21 14 0,000 0,03640131 0,06244972 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03640131 0,06240589 ! non-recombinational repair GO:0000726 29 14 0,000 0,03640131 0,06236213 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03640131 0,06231843 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03640131 0,06227479 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03640131 0,06223121 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03640131 0,06218769 ! lipid localization GO:0010876 32 14 0,000 0,03640131 0,06214423 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03640131 0,06210084 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,03640131 0,0620575 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03640131 0,06201423 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03640131 0,06197101 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03640131 0,06192786 ! arginine metabolic process GO:0006525 21 14 0,000 0,03640131 0,06188476 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03640131 0,06184172 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03640131 0,06179875 ! regulation of heart rate GO:0002027 25 14 0,000 0,03640131 0,06175583 ! fear response GO:0042596 34 14 0,000 0,03640131 0,06171298 ! organic alcohol transport GO:0015850 29 14 0,000 0,03640131 0,06167018 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03640131 0,06162744 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03640131 0,06158476 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03640131 0,06154215 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03640131 0,06149959 ! bone mineralization GO:0030282 18 14 0,000 0,03640131 0,06145708 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03640131 0,06141464 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03640131 0,06137226 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03640131 0,06132993 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03640131 0,06128766 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03640131 0,06124545 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03640131 0,0612033 ! ribosome assembly GO:0042255 18 14 0,000 0,03640131 0,06116121 ! cerebellum development GO:0021549 23 14 0,000 0,03640131 0,06111918 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03640131 0,0610772 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03640131 0,06103528 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03640131 0,06099342 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03640131 0,06095161 ! NADP metabolic process GO:0006739 24 14 0,000 0,03640131 0,06090986 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03640131 0,06086817 ! oxygen transport GO:0015671 22 14 0,000 0,03640131 0,06082654 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03640131 0,06078496 ! male genitalia development GO:0030539 26 14 0,000 0,03640131 0,06074344 ! regulation of RNA stability GO:0043487 33 14 0,000 0,03640131 0,06070198 ! regulation of axon extension GO:0030516 43 14 0,000 0,03640131 0,06066057 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03640131 0,06061922 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03640131 0,06057793 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03895066 0,06477635 ! lactation GO:0007595 30 15 0,000 0,03895066 0,06473228 ! reproductive cellular process GO:0048610 22 15 0,000 0,03895066 0,06468828 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03895066 0,06464433 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,03895066 0,06460044 ! superoxide anion generation GO:0042554 22 15 0,000 0,03895066 0,06455662 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,03895066 0,06451285 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,03895066 0,06446914 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,03895066 0,06442549 ! copper ion transport GO:0006825 22 15 0,000 0,03895066 0,0643819 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,03895066 0,06433837 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,03895066 0,0642949 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,03895066 0,06425149 ! sulfate transport GO:0008272 27 15 0,000 0,03895066 0,06420813 ! response to cAMP GO:0051591 25 15 0,000 0,03895066 0,06416484 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,03895066 0,0641216 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,03895066 0,06407842 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,03895066 0,0640353 ! response to hexose stimulus GO:0009746 25 15 0,000 0,03895066 0,06399223 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,03895066 0,06394923 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,03895066 0,06390628 ! vesicle coating GO:0006901 38 15 0,000 0,03895066 0,06386339 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,03895066 0,06382056 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,03895066 0,06377778 ! regulation of exocytosis GO:0017157 26 15 0,000 0,03895066 0,06373507 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,03895066 0,06369241 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,03895066 0,0636498 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,03895066 0,06360725 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,03895066 0,06356477 ! regulation of vasodilation GO:0042312 27 15 0,000 0,03895066 0,06352233 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,03895066 0,06347996 ! histone deacetylation GO:0016575 24 15 0,000 0,03895066 0,06343764 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03895066 0,06339537 ! water homeostasis GO:0030104 28 15 0,000 0,03895066 0,06335316 ! cofactor transport GO:0051181 30 15 0,000 0,03895066 0,06331101 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03895066 0,06326892 ! muscle maintenance GO:0046716 26 15 0,000 0,03895066 0,06322688 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,03895066 0,0631849 ! intestinal absorption GO:0050892 31 15 0,000 0,03895066 0,06314297 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03895066 0,0631011 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,03895066 0,06305928 ! heme biosynthetic process GO:0006783 33 15 0,000 0,03895066 0,06301752 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,03895066 0,06297581 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,03895066 0,06293416 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,03895066 0,06289257 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,03895066 0,06285103 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,03895066 0,06280954 ! actin filament polymerization GO:0030041 27 15 0,000 0,03895066 0,06276811 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,03895066 0,06272673 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04149333 0,06677747 ! positive regulation of cell size GO:0045793 29 16 0,000 0,04149333 0,06673351 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04149333 0,06668961 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04149333 0,06664576 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04149333 0,06660197 ! bone remodeling GO:0046849 28 16 0,000 0,04149333 0,06655824 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04149333 0,06651457 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04149333 0,06647095 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04149333 0,06642739 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04149333 0,06638389 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04149333 0,06634045 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04149333 0,06629706 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04149333 0,06625373 ! startle response GO:0001964 28 16 0,000 0,04149333 0,06621045 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04149333 0,06616723 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04149333 0,06612407 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04149333 0,06608097 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04149333 0,06603792 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04149333 0,06599492 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04149333 0,06595199 ! pituitary gland development GO:0021983 30 16 0,000 0,04149333 0,06590911 ! response to osmotic stress GO:0006970 27 16 0,000 0,04149333 0,06586628 ! lysosomal transport GO:0007041 31 16 0,000 0,04149333 0,06582351 ! fructose metabolic process GO:0006000 25 16 0,000 0,04149333 0,06578079 ! L-amino acid transport GO:0015807 33 16 0,000 0,04149333 0,06573813 ! stem cell development GO:0048864 46 16 0,000 0,04149333 0,06569553 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04149333 0,06565298 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04149333 0,06561049 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04149333 0,06556805 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04149333 0,06552567 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04149333 0,06548334 ! axon cargo transport GO:0008088 46 16 0,000 0,04149333 0,06544106 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04149333 0,06539884 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04149333 0,06535668 ! DNA replication initiation GO:0006270 28 16 0,000 0,04149333 0,06531456 ! neuron recognition GO:0008038 40 16 0,000 0,04149333 0,06527251 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04149333 0,0652305 ! tissue regeneration GO:0042246 27 16 0,000 0,04149333 0,06518856 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04149333 0,06514666 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04149333 0,06510482 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,04149333 0,06506303 ! biomineral formation GO:0031214 22 16 0,000 0,04149333 0,0650213 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04149333 0,06497962 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04149333 0,06493799 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04149333 0,06489642 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04149333 0,0648549 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04149333 0,06481343 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04149333 0,06477202 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04149333 0,06473065 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,04149333 0,06468935 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,04149333 0,06464809 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04402935 0,06855557 ! metencephalon development GO:0022037 32 17 0,000 0,04402935 0,06851191 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04402935 0,0684683 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,04402935 0,06842474 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04402935 0,06838124 ! signal complex assembly GO:0007172 47 17 0,000 0,04402935 0,0683378 ! endothelial cell migration GO:0043542 31 17 0,000 0,04402935 0,06829441 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04402935 0,06825108 ! glial cell development GO:0021782 28 17 0,000 0,04402935 0,0682078 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04402935 0,06816457 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04402935 0,0681214 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04402935 0,06807829 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04402935 0,06803523 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04402935 0,06799222 ! myoblast differentiation GO:0045445 50 17 0,000 0,04402935 0,06794927 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04402935 0,06790637 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,04402935 0,06786353 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04402935 0,06782074 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04402935 0,06777801 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04402935 0,06773532 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04402935 0,0676927 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,04402935 0,06765012 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,04402935 0,0676076 ! membrane budding GO:0006900 42 17 0,000 0,04402935 0,06756513 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04402935 0,06752272 ! regulation of protein binding GO:0043393 33 17 0,000 0,04402935 0,06748036 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04402935 0,06743805 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04402935 0,0673958 ! genitalia development GO:0048806 32 17 0,000 0,04402935 0,0673536 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04402935 0,06731145 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04402935 0,06726935 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04402935 0,06722731 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04402935 0,06718532 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,04402935 0,06714338 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04402935 0,06710149 ! steroid catabolic process GO:0006706 34 17 0,000 0,04402935 0,06705966 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04402935 0,06701788 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04402935 0,06697615 ! gas transport GO:0015669 26 17 0,000 0,04402935 0,06693447 ! organic cation transport GO:0015695 32 17 0,000 0,04402935 0,06689284 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,04402935 0,06685127 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04402935 0,06680975 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04402935 0,06676828 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,04655873 0,07056015 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,04655873 0,07051641 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,04655873 0,07047272 ! limbic system development GO:0021761 40 18 0,000 0,04655873 0,07042908 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04655873 0,0703855 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,04655873 0,07034197 ! adult walking behavior GO:0007628 36 18 0,000 0,04655873 0,0702985 ! patterning of blood vessels GO:0001569 43 18 0,000 0,04655873 0,07025508 ! heart looping GO:0001947 34 18 0,000 0,04655873 0,07021171 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,04655873 0,07016839 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,04655873 0,07012513 ! centrosome cycle GO:0007098 26 18 0,000 0,04655873 0,07008193 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,04655873 0,07003877 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,04655873 0,06999567 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,04655873 0,06995262 ! glycine metabolic process GO:0006544 30 18 0,000 0,04655873 0,06990963 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04655873 0,06986669 ! response to retinoic acid GO:0032526 31 18 0,000 0,04655873 0,0698238 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,04655873 0,06978096 ! DNA integration GO:0015074 32 18 0,000 0,04655873 0,06973818 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,04655873 0,06969545 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,04655873 0,06965277 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,04655873 0,06961014 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,04655873 0,06956756 ! neural crest cell migration GO:0001755 41 18 0,000 0,04655873 0,06952504 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,04655873 0,06948257 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,04655873 0,06944015 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,04655873 0,06939778 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,04655873 0,06935547 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,04655873 0,0693132 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,04655873 0,06927099 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,04655873 0,06922883 ! detection of bacterium GO:0016045 22 18 0,000 0,04655873 0,06918672 ! nerve development GO:0021675 34 18 0,000 0,04655873 0,06914466 ! defense response to virus GO:0051607 43 18 0,000 0,04655873 0,06910265 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,04655873 0,0690607 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,04655873 0,06901879 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,04908148 0,07271441 ! positive regulation of translation GO:0045727 31 19 0,000 0,04908148 0,07267034 ! negative regulation of defense response GO:0031348 27 19 0,000 0,04908148 0,07262633 ! neuron maturation GO:0042551 46 19 0,000 0,04908148 0,07258236 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,04908148 0,07253845 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,04908148 0,0724946 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,04908148 0,07245079 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,04908148 0,07240704 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,04908148 0,07236335 ! inositol metabolic process GO:0006020 33 19 0,000 0,04908148 0,0723197 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04908148 0,07227611 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,04908148 0,07223257 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,04908148 0,07218908 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,04908148 0,07214565 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,04908148 0,07210226 ! cerebral cortex development GO:0021987 40 19 0,000 0,04908148 0,07205893 ! pigmentation during development GO:0048066 42 19 0,000 0,04908148 0,07201565 ! response to vitamin A GO:0033189 32 19 0,000 0,04908148 0,07197243 ! heme metabolic process GO:0042168 40 19 0,000 0,04908148 0,07192925 ! neuromuscular junction development GO:0007528 43 19 0,000 0,04908148 0,07188613 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,04908148 0,07184306 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,04908148 0,07180004 ! response to fungus GO:0009620 26 19 0,000 0,04908148 0,07175707 ! peptide cross-linking GO:0018149 39 19 0,000 0,04908148 0,07171415 ! protein export from nucleus GO:0006611 40 19 0,000 0,04908148 0,07167129 ! heart process GO:0003015 32 19 0,000 0,04908148 0,07162847 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,04908148 0,07158571 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,04908148 0,071543 ! visual learning GO:0008542 38 19 0,000 0,04908148 0,07150034 ! cellular pigmentation GO:0033059 37 19 0,000 0,04908148 0,07145773 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,04908148 0,07141517 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,04908148 0,07137266 ! vitamin transport GO:0051180 31 19 0,000 0,04908148 0,0713302 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,04908148 0,07128779 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,04908148 0,07124543 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,04908148 0,07120313 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,04908148 0,07116087 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,04908148 0,07111866 ! cilium assembly GO:0042384 38 19 0,000 0,04908148 0,0710765 ! peptide hormone secretion GO:0030072 32 19 0,000 0,04908148 0,0710344 ! protein secretion GO:0009306 45 20 0,000 0,05159764 0,07463175 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05159764 0,07458759 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,05159764 0,07454348 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05159764 0,07449942 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,05159764 0,07445542 ! skin development GO:0043588 42 20 0,000 0,05159764 0,07441147 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,05159764 0,07436757 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05159764 0,07432372 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05159764 0,07427992 ! response to vitamin GO:0033273 36 20 0,000 0,05159764 0,07423618 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,05159764 0,07419248 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05159764 0,07414884 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05159764 0,07410525 ! response to alkaloid GO:0043279 38 20 0,000 0,05159764 0,07406171 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05159764 0,07401822 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,05159764 0,07397478 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05159764 0,07393139 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05159764 0,07388806 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,05159764 0,07384477 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,05159764 0,07380154 ! actin filament bundle formation GO:0051017 47 20 0,000 0,05159764 0,07375835 ! body fluid secretion GO:0007589 33 20 0,000 0,05159764 0,07371522 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05159764 0,07367214 ! peptide secretion GO:0002790 38 20 0,000 0,05159764 0,0736291 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05159764 0,07358612 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,05159764 0,07354319 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05159764 0,07350031 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05159764 0,07345747 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05159764 0,07341469 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05159764 0,07337196 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,05159764 0,07332928 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05159764 0,07328664 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05159764 0,07324406 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05159764 0,07320152 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05159764 0,07315904 ! regulation of glucose import GO:0046324 30 20 0,000 0,05159764 0,0731166 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05159764 0,07307422 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,05159764 0,07303188 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05159764 0,07298959 ! negative regulation of translation GO:0017148 32 20 0,000 0,05159764 0,07294735 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05159764 0,07290516 ! regulation of cell killing GO:0031341 46 21 0,000 0,0541072 0,07640688 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,0541072 0,07636274 ! hormone secretion GO:0046879 39 21 0,000 0,0541072 0,07631865 ! cAMP metabolic process GO:0046058 41 21 0,000 0,0541072 0,07627461 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,0541072 0,07623062 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,0541072 0,07618668 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,0541072 0,0761428 ! ovarian follicle development GO:0001541 39 21 0,000 0,0541072 0,07609896 ! smooth muscle contraction GO:0006939 48 21 0,000 0,0541072 0,07605518 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,0541072 0,07601144 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,0541072 0,07596776 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,0541072 0,07592412 ! plasma membrane fusion GO:0045026 33 21 0,000 0,0541072 0,07588054 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,0541072 0,075837 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,0541072 0,07579352 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,0541072 0,07575008 ! sensory perception of pain GO:0019233 33 21 0,000 0,0541072 0,0757067 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,0541072 0,07566336 ! diencephalon development GO:0021536 36 21 0,000 0,0541072 0,07562008 ! collagen fibril organization GO:0030199 62 21 0,000 0,0541072 0,07557684 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,0541072 0,07553365 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,0541072 0,07549052 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,0541072 0,07544743 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,0541072 0,07540439 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,0541072 0,0753614 ! collagen catabolic process GO:0030574 29 21 0,000 0,0541072 0,07531846 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,0541072 0,07527557 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,0541072 0,07523272 ! sperm-egg recognition GO:0035036 23 21 0,000 0,0541072 0,07518993 ! actin filament-based movement GO:0030048 47 21 0,000 0,0541072 0,07514718 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,0566102 0,07857881 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,0566102 0,07853419 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,0566102 0,07848962 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,0566102 0,0784451 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,0566102 0,07840063 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,0566102 0,07835621 ! microtubule-based transport GO:0010970 59 22 0,000 0,0566102 0,07831184 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,0566102 0,07826752 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,0566102 0,07822325 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,0566102 0,07817904 ! vacuolar transport GO:0007034 41 22 0,000 0,0566102 0,07813487 ! central nervous system neuron development GO:0021954 47 22 0,000 0,0566102 0,07809075 ! fucose metabolic process GO:0006004 44 22 0,000 0,0566102 0,07804668 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,0566102 0,07800266 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,0566102 0,07795869 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,0566102 0,07791477 ! ureteric bud development GO:0001657 50 22 0,000 0,0566102 0,0778709 ! stem cell differentiation GO:0048863 57 22 0,000 0,0566102 0,07782708 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,0566102 0,0777833 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,0566102 0,07773958 ! renal system process GO:0003014 42 22 0,000 0,0566102 0,07769591 ! vasodilation GO:0042311 40 22 0,000 0,0566102 0,07765228 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,0566102 0,07760871 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,0566102 0,07756518 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,0566102 0,0775217 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,0566102 0,07747827 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,0566102 0,07743489 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,0566102 0,07739156 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,0566102 0,07734827 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,0566102 0,07730504 ! sarcomere organization GO:0045214 32 22 0,000 0,0566102 0,07726185 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,0566102 0,07721871 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,0566102 0,07717562 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,0566102 0,07713258 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,0566102 0,07708958 ! gut development GO:0048565 44 22 0,000 0,0566102 0,07704664 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,0566102 0,07700374 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,0566102 0,07696089 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,0566102 0,07691808 ! protein stabilization GO:0050821 41 22 0,000 0,0566102 0,07687533 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,05910664 0,08022085 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,05910664 0,0801763 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,05910664 0,08013181 ! gluconeogenesis GO:0006094 38 23 0,000 0,05910664 0,08008737 ! glycerol metabolic process GO:0006071 40 23 0,000 0,05910664 0,08004297 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,05910664 0,07999863 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,05910664 0,07995433 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,05910664 0,07991009 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,05910664 0,07986589 ! regeneration GO:0031099 42 23 0,000 0,05910664 0,07982174 ! axis specification GO:0009798 43 23 0,000 0,05910664 0,07977764 ! visual behavior GO:0007632 46 23 0,000 0,05910664 0,07973359 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,05910664 0,07968958 ! response to ethanol GO:0045471 47 23 0,000 0,05910664 0,07964563 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,05910664 0,07960172 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,05910664 0,07955786 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,05910664 0,07951406 ! peroxisome organization GO:0007031 43 23 0,000 0,05910664 0,07947029 ! lysosome organization GO:0007040 47 23 0,000 0,05910664 0,07942658 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,05910664 0,07938292 ! vesicle targeting GO:0006903 49 23 0,000 0,05910664 0,0793393 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,05910664 0,07929573 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,05910664 0,07925221 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,05910664 0,07920874 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,05910664 0,07916531 ! DNA modification GO:0006304 36 23 0,000 0,05910664 0,07912193 ! fatty acid transport GO:0015908 47 23 0,000 0,05910664 0,0790786 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,05910664 0,07903532 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,05910664 0,07899208 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,05910664 0,07894889 ! hormone transport GO:0009914 41 23 0,000 0,05910664 0,07890575 ! cell-cell recognition GO:0009988 28 23 0,000 0,05910664 0,07886266 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,05910664 0,07881961 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,05910664 0,07877661 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,05910664 0,07873366 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06159655 0,08200565 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06159655 0,08196098 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,06159655 0,08191637 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06159655 0,0818718 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06159655 0,08182728 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06159655 0,08178281 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06159655 0,08173838 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06159655 0,08169401 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,06159655 0,08164968 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06159655 0,0816054 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06159655 0,08156117 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06159655 0,08151699 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06159655 0,08147286 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,06159655 0,08142877 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,06159655 0,08138473 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06159655 0,08134074 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06159655 0,08129679 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06159655 0,0812529 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06159655 0,08120905 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06159655 0,08116525 ! membrane depolarization GO:0051899 45 24 0,000 0,06159655 0,08112149 ! pallium development GO:0021543 56 24 0,000 0,06159655 0,08107778 ! oogenesis GO:0048477 44 24 0,000 0,06159655 0,08103412 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06159655 0,08099051 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,06159655 0,08094694 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,06159655 0,08090342 ! platelet activation GO:0030168 41 24 0,000 0,06159655 0,08085995 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06159655 0,08081652 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06159655 0,08077314 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06159655 0,08072981 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06159655 0,08068652 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06159655 0,08064328 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,06159655 0,08060009 ! regulation of amine transport GO:0051952 41 24 0,000 0,06159655 0,08055694 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,06159655 0,08051384 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06407994 0,08371512 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06407994 0,08367038 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06407994 0,08362568 ! phototransduction GO:0007602 37 25 0,000 0,06407994 0,08358104 ! keratinization GO:0031424 37 25 0,000 0,06407994 0,08353644 ! vasculogenesis GO:0001570 49 25 0,000 0,06407994 0,08349188 ! vacuole organization GO:0007033 49 25 0,000 0,06407994 0,08344738 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06407994 0,08340292 ! receptor metabolic process GO:0043112 53 25 0,000 0,06407994 0,08335851 ! chromosome condensation GO:0030261 48 25 0,000 0,06407994 0,08331415 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,06407994 0,08326983 ! regulation of behavior GO:0050795 48 25 0,000 0,06407994 0,08322556 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06407994 0,08318134 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06407994 0,08313717 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06407994 0,08309304 ! immunoglobulin production GO:0002377 62 25 0,000 0,06407994 0,08304896 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06407994 0,08300492 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06407994 0,08296093 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06407994 0,08291699 ! liver development GO:0001889 55 25 0,000 0,06407994 0,0828731 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,06655682 0,08603085 ! myelination GO:0042552 50 26 0,000 0,06655682 0,08598536 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,06655682 0,08593991 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,06655682 0,08589451 ! molting cycle process GO:0022404 52 26 0,000 0,06655682 0,08584916 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,06655682 0,08580386 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,06655682 0,0857586 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,06655682 0,0857134 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,06655682 0,08566824 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,06655682 0,08562312 ! digestive system process GO:0022600 49 26 0,000 0,06655682 0,08557806 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,06655682 0,08553304 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,06655682 0,08548807 ! osteoblast differentiation GO:0001649 63 26 0,000 0,06655682 0,08544315 ! neural crest cell development GO:0014032 59 26 0,000 0,06655682 0,08539827 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,06655682 0,08535344 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,06655682 0,08530866 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,06655682 0,08526393 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,06655682 0,08521924 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,06655682 0,0851746 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,06655682 0,08513001 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,06655682 0,08508546 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,06655682 0,08504096 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,06655682 0,0849965 ! blastocyst development GO:0001824 50 26 0,000 0,06655682 0,0849521 ! telomere organization GO:0032200 46 26 0,000 0,06655682 0,08490773 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,06655682 0,08486342 ! neural tube closure GO:0001843 58 26 0,000 0,06655682 0,08481915 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,06655682 0,08477493 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,06655682 0,08473075 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,06655682 0,08468662 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,06902722 0,08778423 ! embryonic pattern specification GO:0009880 49 27 0,000 0,06902722 0,08773855 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,06902722 0,08769293 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,06902722 0,08764735 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,06902722 0,08760182 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,06902722 0,08755633 ! iron ion transport GO:0006826 65 27 0,000 0,06902722 0,0875109 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,06902722 0,08746551 ! superoxide metabolic process GO:0006801 41 27 0,000 0,06902722 0,08742017 ! tube lumen formation GO:0035148 59 27 0,000 0,06902722 0,08737487 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,06902722 0,08732962 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,06902722 0,08728442 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,06902722 0,08723926 ! response to toxin GO:0009636 49 27 0,000 0,06902722 0,08719416 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,06902722 0,0871491 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,06902722 0,08710408 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,06902722 0,08705911 ! leukocyte proliferation GO:0070661 59 27 0,000 0,06902722 0,08701419 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,06902722 0,08696931 ! neuron fate commitment GO:0048663 52 28 0,000 0,07149115 0,09002726 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 0,000 0,07149115 0,08998088 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07149115 0,08993454 ! vesicle docking GO:0048278 55 28 0,000 0,07149115 0,08988826 ! circadian rhythm GO:0007623 56 28 0,000 0,07149115 0,08984202 ! dendrite development GO:0016358 67 28 0,000 0,07149115 0,08979583 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,07149115 0,08974968 ! fat cell differentiation GO:0045444 57 28 0,000 0,07149115 0,08970359 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07149115 0,08965754 ! sperm motility GO:0030317 37 28 0,000 0,07149115 0,08961154 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07149115 0,08956558 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07149115 0,08951967 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07149115 0,08947381 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07149115 0,089428 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07149115 0,08938223 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07149115 0,08933651 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07149115 0,08929084 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07149115 0,08924521 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07149115 0,08919963 ! lipid oxidation GO:0034440 48 28 0,000 0,07149115 0,0891541 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07149115 0,08910861 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,07149115 0,08906317 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,07394863 0,09207773 ! translational initiation GO:0006413 66 29 0,000 0,07394863 0,09203082 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,07394863 0,09198396 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,07394863 0,09193715 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,07394863 0,09189039 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,07394863 0,09184367 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07394863 0,091797 ! primary neural tube formation GO:0014020 61 29 0,000 0,07394863 0,09175038 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,07394863 0,09170381 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,07394863 0,09165728 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,07394863 0,0916108 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,07394863 0,09156437 ! synaptogenesis GO:0007416 46 29 0,000 0,07394863 0,09151799 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,07394863 0,09147165 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07394863 0,09142536 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07394863 0,09137911 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07394863 0,09133291 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,07639967 0,09431248 ! phenol metabolic process GO:0018958 56 30 0,000 0,07639967 0,09426485 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,07639967 0,09421727 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,07639967 0,09416973 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,07639967 0,09412224 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,07639967 0,0940748 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,07639967 0,09402741 ! acute-phase response GO:0006953 50 30 0,000 0,07639967 0,09398006 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,07639967 0,09393277 ! myofibril assembly GO:0030239 50 30 0,000 0,07639967 0,09388552 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,07639967 0,09383831 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,07639967 0,09379116 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,07639967 0,09374405 ! cell fate determination GO:0001709 64 30 0,000 0,07639967 0,09369699 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,07639967 0,09364998 ! phospholipid transport GO:0015914 65 30 0,000 0,07639967 0,09360301 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,07639967 0,09355609 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,07639967 0,09350922 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,07639967 0,0934624 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,07639967 0,09341562 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,07639967 0,09336889 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,07639967 0,0933222 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,0788443 0,09626018 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,0788443 0,0962121 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,0788443 0,09616407 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,0788443 0,09611608 ! regulation of innate immune response GO:0045088 57 31 0,000 0,0788443 0,09606814 ! ovulation cycle process GO:0022602 55 31 0,000 0,0788443 0,09602025 ! peptide transport GO:0015833 60 31 0,000 0,0788443 0,09597241 ! male gonad development GO:0008584 56 31 0,000 0,0788443 0,09592461 ! iron ion homeostasis GO:0055072 60 31 0,000 0,0788443 0,09587687 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,0788443 0,09582917 ! detection of light stimulus GO:0009583 44 31 0,000 0,0788443 0,09578151 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,0788443 0,09573391 ! natural killer cell activation GO:0030101 50 31 0,000 0,0788443 0,09568635 ! ensheathment of neurons GO:0007272 64 31 0,000 0,0788443 0,09563884 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,0788443 0,09559138 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,0788443 0,09554396 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,0788443 0,09549659 ! eye morphogenesis GO:0048592 65 31 0,000 0,0788443 0,09544927 ! response to heat GO:0009408 54 31 0,000 0,0788443 0,09540199 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,0788443 0,09535476 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,08128252 0,09825493 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,08128252 0,09820633 ! collagen metabolic process GO:0032963 49 32 0,000 0,08128252 0,09815779 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,08128252 0,09810929 ! spindle organization GO:0007051 50 32 0,000 0,08128252 0,09806084 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,08128252 0,09801244 ! metanephros development GO:0001656 81 32 0,000 0,08128252 0,09796409 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,08128252 0,09791578 ! muscle cell development GO:0055001 52 32 0,000 0,08128252 0,09786752 ! mesoderm formation GO:0001707 73 32 0,000 0,08128252 0,09781931 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,08128252 0,09777115 ! ovulation cycle GO:0042698 57 32 0,000 0,08128252 0,09772303 ! peripheral nervous system development GO:0007422 68 32 0,000 0,08128252 0,09767497 ! BMP signaling pathway GO:0030509 71 32 0,000 0,08128252 0,09762694 ! hindbrain development GO:0030902 65 32 0,000 0,08128252 0,09757897 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,08128252 0,09753104 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,08128252 0,09748316 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,08371436 0,10035043 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,08371436 0,10030122 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,08371436 0,10025205 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,08371436 0,10020293 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,08371436 0,10015386 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,08371436 0,10010484 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,08371436 0,10005586 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,08371436 0,10000694 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,08371436 0,09995806 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,08371436 0,09990923 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,08371436 0,09986044 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,08371436 0,09981171 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,08613983 0,10265347 ! glial cell differentiation GO:0010001 67 34 0,000 0,08613983 0,10260342 ! post-embryonic development GO:0009791 76 34 0,000 0,08613983 0,10255342 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,08613983 0,10250346 ! cholesterol transport GO:0030301 62 34 0,000 0,08613983 0,10245356 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,08613983 0,1024037 ! spliceosome assembly GO:0000245 75 34 0,000 0,08613983 0,1023539 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,08613983 0,10230414 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,08613983 0,10225443 ! formation of primary germ layer GO:0001704 76 34 0,000 0,08613983 0,10220476 ! cell fate specification GO:0001708 56 34 0,000 0,08613983 0,10215515 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,08613983 0,10210558 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,08613983 0,10205607 ! adult locomotory behavior GO:0008344 62 34 0,000 0,08613983 0,1020066 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,08855895 0,1048205 ! negative regulation of secretion GO:0051048 68 35 0,000 0,08855895 0,10476974 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,08855895 0,10471903 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,08855895 0,10466837 ! membrane docking GO:0022406 69 35 0,000 0,08855895 0,10461775 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,08855895 0,10456719 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,08855895 0,10451667 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,08855895 0,10446621 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,08855895 0,10441579 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,08855895 0,10436542 ! ceramide metabolic process GO:0006672 72 35 0,000 0,08855895 0,1043151 ! telencephalon development GO:0021537 81 35 0,000 0,08855895 0,10426483 ! sterol transport GO:0015918 63 35 0,000 0,08855895 0,1042146 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,08855895 0,10416443 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,08855895 0,1041143 ! placenta development GO:0001890 53 35 0,000 0,08855895 0,10406422 ! vesicle localization GO:0051648 70 35 0,000 0,08855895 0,10401419 ! regulation of muscle development GO:0048634 82 36 0,000 0,09097173 0,1067967 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,09097173 0,10674541 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,09097173 0,10669416 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,09097173 0,10664296 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,09097173 0,10659182 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,09097173 0,10654072 ! positive regulation of cell development GO:0010720 85 36 0,000 0,09097173 0,10648967 ! protein targeting to membrane GO:0006612 75 36 0,000 0,09097173 0,10643867 ! regulation of proteolysis GO:0030162 77 36 0,000 0,09097173 0,10638772 ! aerobic respiration GO:0009060 56 36 0,000 0,09097173 0,10633681 ! cytokine production GO:0001816 68 36 0,000 0,09097173 0,10628596 ! embryonic organ development GO:0048568 67 36 0,000 0,09097173 0,10623515 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,09097173 0,10618439 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,09097173 0,10613369 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,09337819 0,10888922 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,09337819 0,10883727 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,09337819 0,10878537 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,09337819 0,10873352 ! sister chromatid segregation GO:0000819 65 37 0,000 0,09337819 0,10868172 ! odontogenesis GO:0042476 74 37 0,000 0,09337819 0,10862996 ! actomyosin structure organization GO:0031032 68 37 0,000 0,09337819 0,10857826 ! tissue remodeling GO:0048771 78 37 0,000 0,09337819 0,10852661 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,09337819 0,108475 ! female gonad development GO:0008585 71 37 0,000 0,09337819 0,10842344 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,09337819 0,10837194 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,09337819 0,10832048 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,09337819 0,10826907 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,09337819 0,10821771 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,09577835 0,11094666 ! meiosis I GO:0007127 74 38 0,000 0,09577835 0,11089408 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,09577835 0,11084155 ! organic anion transport GO:0015711 82 38 0,000 0,09577835 0,11078907 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,09577835 0,11073664 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,09577835 0,11068425 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,09577835 0,11063192 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,09577835 0,11057964 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,09577835 0,1105274 ! regulation of protein stability GO:0031647 77 38 0,000 0,09577835 0,11047522 ! spermatid development GO:0007286 69 38 0,000 0,09577835 0,11042308 ! glycogen metabolic process GO:0005977 63 38 0,000 0,09577835 0,110371 ! pigment metabolic process GO:0042440 87 38 0,000 0,09577835 0,11031896 ! neural tube formation GO:0001841 79 38 0,000 0,09577835 0,11026697 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,09817222 0,11296973 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,09817222 0,11291655 ! negative regulation of binding GO:0051100 71 39 0,000 0,09817222 0,11286341 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,09817222 0,11281032 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,09817222 0,11275728 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,09817222 0,1127043 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,09817222 0,11265136 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,09817222 0,11259847 ! glucan metabolic process GO:0044042 64 39 0,000 0,09817222 0,11254563 GO:0006073|cellular glucan metabolic process, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,10055983 0,11522873 ! learning GO:0007612 82 40 0,000 0,10055983 0,11517471 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,10055983 0,11512074 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,10055983 0,11506682 ! lipid homeostasis GO:0055088 75 40 0,000 0,10055983 0,11501295 ! mismatch repair GO:0006298 58 40 0,000 0,10055983 0,11495913 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,10055983 0,11490536 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,10055983 0,11485164 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,10055983 0,11479797 ! RNA export from nucleus GO:0006405 61 41 0,000 0,10294117 0,1174616 ! mRNA catabolic process GO:0006402 79 41 0,000 0,10294117 0,11740676 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,10294117 0,11735198 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,10294117 0,11729724 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,10294117 0,11724256 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,10294117 0,11718793 ! feeding behavior GO:0007631 69 41 0,000 0,10294117 0,11713334 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,10294117 0,11707881 ! mesenchymal cell development GO:0014031 94 41 0,000 0,10294117 0,11702433 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,10294117 0,1169699 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,10294117 0,11691552 ! spermatid differentiation GO:0048515 73 41 0,000 0,10294117 0,11686119 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,10294117 0,11680692 ! RNA modification GO:0009451 64 41 0,000 0,10294117 0,11675269 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,10531628 0,11939104 ! ear morphogenesis GO:0042471 64 42 0,000 0,10531628 0,11933566 ! organic ether metabolic process GO:0018904 59 42 0,000 0,10531628 0,11928033 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,10531628 0,11922506 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,10531628 0,11916984 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,10531628 0,11911467 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,10531628 0,11905955 ! regulation of protein secretion GO:0050708 77 42 0,000 0,10531628 0,11900448 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,10531628 0,11894946 ! cytokinesis GO:0000910 84 42 0,000 0,10531628 0,11889449 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,10531628 0,11883958 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,10768517 0,12145654 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,10768517 0,1214005 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,10768517 0,1213445 ! regulation of tube size GO:0035150 76 43 0,000 0,10768517 0,12128856 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,10768517 0,12123266 ! glucose transport GO:0015758 66 43 0,000 0,10768517 0,12117682 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,10768517 0,12112103 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,10768517 0,12106529 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,10768517 0,1210096 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,10768517 0,12095397 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,10768517 0,12089838 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,10768517 0,12084285 ! ion transmembrane transport GO:0034220 79 43 0,000 0,10768517 0,12078736 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,11004785 0,12338087 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,11004785 0,12332427 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,11004785 0,12326773 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,11004785 0,12321123 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,11004785 0,12315479 ! hexose transport GO:0008645 68 44 0,000 0,11004785 0,1230984 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,11004785 0,12304206 ! striated muscle contraction GO:0006941 85 44 0,000 0,11004785 0,12298578 ! phagocytosis GO:0006909 105 44 0,000 0,11004785 0,12292954 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,11004785 0,12287336 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,11240435 0,12544715 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,11240435 0,12538987 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,11240435 0,12533264 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,11240435 0,12527547 ! female gamete generation GO:0007292 71 45 0,000 0,11240435 0,12521834 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,11240435 0,12516127 ! polyol metabolic process GO:0019751 77 45 0,000 0,11240435 0,12510425 ! developmental growth GO:0048589 88 45 0,000 0,11240435 0,12504728 ! maintenance of location in cell GO:0051651 101 45 0,000 0,11240435 0,12499036 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,11475467 0,12754579 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,11475467 0,12748779 ! glycolysis GO:0006096 71 46 0,000 0,11475467 0,12742984 ! leukocyte migration GO:0050900 75 46 0,000 0,11475467 0,12737195 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,11475467 0,1273141 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,11475467 0,12725631 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,11475467 0,12719857 ! pigmentation GO:0043473 103 46 0,000 0,11475467 0,12714089 ! cell growth GO:0016049 90 46 0,000 0,11475467 0,12708325 ! neural tube development GO:0021915 91 47 0,000 0,11709883 0,1296205 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,11709883 0,12956179 ! positive regulation of cell cycle GO:0045787 96 48 0,000 0,11943685 0,13208883 ! positive regulation of defense response GO:0031349 88 48 0,000 0,11943685 0,13202906 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,11943685 0,13196935 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,11943685 0,13190969 ! cellular component disassembly GO:0022411 89 48 0,000 0,11943685 0,13185008 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,11943685 0,13179053 ! endosome transport GO:0016197 127 48 0,000 0,11943685 0,13173103 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,11943685 0,13167158 ! male sex differentiation GO:0046661 93 48 0,000 0,11943685 0,13161219 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,11943685 0,13155285 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,11943685 0,13149357 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,11943685 0,13143434 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,11943685 0,13137516 ! response to calcium ion GO:0051592 94 49 0,000 0,12176874 0,13387986 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,12176874 0,13381963 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,12176874 0,13375946 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,12176874 0,13369935 ! JNK cascade GO:0007254 106 49 0,000 0,12176874 0,13363928 ! regulation of action potential GO:0001508 102 50 0,000 0,12409453 0,13613064 ! regulation of ion transport GO:0043269 86 50 0,000 0,12409453 0,13606954 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,12409453 0,1360085 ! endocrine system development GO:0035270 109 50 0,000 0,12409453 0,1359475 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,12409453 0,13588657 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,12409453 0,13582569 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,12409453 0,13576486 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,12409453 0,13570409 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,12409453 0,13564337 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,12641422 0,13811715 ! peptide metabolic process GO:0006518 80 51 0,000 0,12641422 0,1380554 ! response to temperature stimulus GO:0009266 84 51 0,000 0,12641422 0,13799372 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,12641422 0,13793209 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,12641422 0,13787051 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,12872783 0,14033115 ! Notch signaling pathway GO:0007219 111 52 0,000 0,12872783 0,14026855 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,12872783 0,14020602 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,12872783 0,14014354 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,12872783 0,14008111 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,12872783 0,14001874 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,12872783 0,13995643 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,12872783 0,13989417 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,12872783 0,13983197 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,12872783 0,13976982 ! amino acid activation GO:0043038 98 52 0,000 0,12872783 0,13970773 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,13103538 0,14214895 ! inner ear development GO:0048839 89 53 0,000 0,13103538 0,14208586 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,13103538 0,14202282 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,13103538 0,14195984 ! vesicle organization GO:0016050 127 53 0,000 0,13103538 0,14189692 ! cartilage development GO:0051216 99 53 0,000 0,13103538 0,14183405 ! synapse organization GO:0050808 102 53 0,000 0,13103538 0,14177123 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,13333689 0,14419744 ! regulation of translational initiation GO:0006446 87 54 0,000 0,13333689 0,14413364 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,13333689 0,14406989 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,13333689 0,1440062 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,13333689 0,14394256 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,13333689 0,14387898 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,13333689 0,14381546 ! membrane fusion GO:0006944 122 54 0,000 0,13333689 0,14375199 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,13333689 0,14368858 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,13333689 0,14362523 ! regulation of cell shape GO:0008360 142 54 0,000 0,13333689 0,14356193 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,13333689 0,14349869 ! RNA catabolic process GO:0006401 103 55 0,000 0,13563236 0,14590482 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,13563236 0,14584061 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,13563236 0,14577644 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,13563236 0,14571234 ! cell recognition GO:0008037 98 55 0,000 0,13563236 0,14564829 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,13563236 0,1455843 ! cell maturation GO:0048469 107 55 0,000 0,13563236 0,14552036 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,13563236 0,14545648 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,13563236 0,14539265 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,13792182 0,14778202 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,13792182 0,14771723 ! glucose catabolic process GO:0006007 88 56 0,000 0,13792182 0,1476525 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,13792182 0,14758782 ! RNA elongation GO:0006354 90 56 0,000 0,13792182 0,14752321 ! chloride transport GO:0006821 102 57 0,000 0,14020528 0,1499 ! muscle fiber development GO:0048747 131 57 0,000 0,14020528 0,14983442 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,14020528 0,14976891 ! regulation of actin filament length GO:0030832 118 58 0,000 0,14248275 0,15213521 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,14248275 0,15206874 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,14248275 0,15200234 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,14248275 0,15193599 ! gastrulation GO:0007369 122 58 0,000 0,14248275 0,1518697 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,14248275 0,15180347 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,14248275 0,1517373 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,14248275 0,15167118 ! maintenance of location GO:0051235 124 58 0,000 0,14248275 0,15160512 ! nuclear export GO:0051168 110 59 0,000 0,14475425 0,153955 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,14701981 0,15629651 ! DNA catabolic process GO:0006308 94 60 0,000 0,14701981 0,15622853 ! regulation of endocytosis GO:0030100 104 60 0,000 0,14701981 0,1561606 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,14701981 0,15609274 ! adult behavior GO:0030534 104 60 0,000 0,14701981 0,15602493 ! kidney development GO:0001822 133 60 0,000 0,14701981 0,15595718 ! positive regulation of secretion GO:0051047 110 61 0,000 0,14927942 0,15828543 ! regulation of cellular component size GO:0032535 125 61 0,000 0,14927942 0,15821676 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,14927942 0,15814815 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,14927942 0,15807959 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,14927942 0,1580111 ! regulation of heart contraction GO:0008016 123 61 0,000 0,14927942 0,15794267 ! camera-type eye development GO:0043010 126 61 0,000 0,14927942 0,1578743 ! proton transport GO:0015992 117 61 0,000 0,14927942 0,15780598 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,14927942 0,15773773 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,15153311 0,16004989 ! tRNA processing GO:0008033 102 62 0,000 0,15153311 0,15998072 ! mesoderm development GO:0007498 128 63 0,000 0,1537809 0,16228368 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,1537809 0,16221361 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,1537809 0,1621436 ! hydrogen transport GO:0006818 121 64 0,000 0,15602279 0,16443644 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,15602279 0,16436553 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,1582588 0,16664925 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,1582588 0,16657745 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,1582588 0,16650571 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,1582588 0,16643403 ! ear development GO:0043583 114 66 0,000 0,16048896 0,16870677 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,16048896 0,16863421 ! gonad development GO:0008406 115 66 0,000 0,16048896 0,16856171 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,16048896 0,16848927 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,16271327 0,17075108 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,16271327 0,17067777 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,16271327 0,17060451 ! secondary metabolic process GO:0019748 125 67 0,000 0,16271327 0,17053132 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,16493175 0,17278227 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,16493175 0,17270821 ! hexose catabolic process GO:0019320 113 68 0,000 0,16493175 0,17263422 ! extracellular matrix organization GO:0030198 146 68 0,000 0,16493175 0,17256028 ! detection of external stimulus GO:0009581 102 68 0,000 0,16493175 0,17248641 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,16493175 0,17241261 ! regulation of lipase activity GO:0060191 137 68 0,000 0,16493175 0,17233886 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,16714441 0,17457623 ! urogenital system development GO:0001655 149 69 0,000 0,16714441 0,17450162 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,16714441 0,17442708 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,16714441 0,1743526 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,16714441 0,17427819 ! developmental maturation GO:0021700 128 69 0,000 0,16714441 0,17420384 ! single fertilization GO:0007338 83 69 0,000 0,16714441 0,17412955 ! cell redox homeostasis GO:0045454 114 70 0,000 0,16935127 0,17635343 ! germ cell development GO:0007281 133 70 0,000 0,16935127 0,17627829 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,17155235 0,17849335 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,17155235 0,17841736 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,17155235 0,17834144 ! appendage morphogenesis GO:0035107 150 72 0,000 0,17374765 0,1805468 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,17374765 0,18047003 ! actin filament organization GO:0007015 167 72 0,000 0,17374765 0,18039334 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,17374765 0,1803167 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,17374765 0,18024013 ! appendage development GO:0048736 151 73 0,000 0,1759372 0,18243404 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,1759372 0,18235664 ! regulation of immune effector process GO:0002697 156 73 0,000 0,1759372 0,1822793 ! amino acid transport GO:0006865 148 74 0,000 0,17812101 0,1844636 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,17812101 0,18438544 ! transition metal ion transport GO:0000041 143 75 0,000 0,1802991 0,18656107 ! reproductive structure development GO:0048608 131 75 0,000 0,1802991 0,18648209 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,1802991 0,18640317 ! eye development GO:0001654 155 75 0,000 0,1802991 0,18632432 ! axon guidance GO:0007411 162 75 0,000 0,1802991 0,18624554 ! rhythmic process GO:0048511 142 75 0,000 0,1802991 0,18616682 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,18247147 0,18833029 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,18247147 0,18825076 ! regulation of blood pressure GO:0008217 134 76 0,000 0,18247147 0,1881713 ! amine catabolic process GO:0009310 136 77 0,000 0,18463815 0,19032531 ! neurotransmitter transport GO:0006836 142 77 0,000 0,18463815 0,19024504 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,18463815 0,19016484 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,18463815 0,1900847 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,18463815 0,19000463 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,18679914 0,1921475 ! antigen processing and presentation GO:0019882 117 78 0,000 0,18679914 0,19206663 ! fertilization GO:0009566 99 78 0,000 0,18679914 0,19198582 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,18895447 0,19411933 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,18895447 0,19403773 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,18895447 0,19395621 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,18895447 0,19387475 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,19110415 0,19599808 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,19110415 0,19591583 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,19110415 0,19583365 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,19110415 0,19575154 ! meiosis GO:0007126 143 81 0,000 0,19324819 0,19786476 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,19324819 0,19778187 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,19324819 0,19769904 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,19324819 0,19761629 ! meiotic cell cycle GO:0051321 144 82 0,000 0,1953866 0,19971944 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,19751941 0,20181511 ! exocytosis GO:0006887 153 83 0,000 0,19751941 0,20173074 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,19751941 0,20164644 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,19751941 0,20156221 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,19751941 0,20147805 ! inorganic anion transport GO:0015698 156 83 0,000 0,19751941 0,20139396 ! response to metal ion GO:0010038 158 84 0,000 0,19964663 0,20347798 ! response to nutrient GO:0007584 135 84 0,000 0,19964663 0,20339312 ! digestion GO:0007586 130 84 0,000 0,19964663 0,20330834 ! negative regulation of transport GO:0051051 164 85 0,000 0,20176826 0,20538328 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,20176826 0,20529774 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,20176826 0,20521227 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,20176826 0,20512687 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,20388433 0,20719194 ! regulation of lyase activity GO:0051339 169 86 0,000 0,20388433 0,20710579 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,20599486 0,20916269 ! alcohol catabolic process GO:0046164 142 87 0,000 0,20599486 0,20907579 ! nucleosome assembly GO:0006334 126 87 0,000 0,20599486 0,20898897 ! cellular respiration GO:0045333 143 88 0,000 0,20809984 0,21103691 ! amine biosynthetic process GO:0009309 146 88 0,000 0,20809984 0,21094934 ! sensory perception of smell GO:0007608 117 88 0,000 0,20809984 0,21086185 ! chromatin assembly GO:0031497 128 88 0,000 0,20809984 0,21077442 ! tube morphogenesis GO:0035239 194 89 0,000 0,21019931 0,21281264 ! cellular defense response GO:0006968 123 89 0,000 0,21019931 0,21272448 ! regulation of neurological system process GO:0031644 175 89 0,000 0,21019931 0,2126364 ! response to inorganic substance GO:0010035 173 90 0,000 0,21229326 0,21466575 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,21229326 0,21457693 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,21229326 0,21448819 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,21438173 0,21650871 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,21438173 0,21641924 ! defense response to bacterium GO:0042742 112 91 0,000 0,21438173 0,21632985 ! bone development GO:0060348 206 92 0,000 0,21646471 0,21834158 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,21646471 0,21825146 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,21854224 0,22025523 ! amine transport GO:0015837 181 93 0,000 0,21854224 0,22016441 ! vitamin metabolic process GO:0006766 153 93 0,000 0,21854224 0,22007365 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,22061431 0,22206871 ! female pregnancy GO:0007565 166 94 0,000 0,22061431 0,22197725 ! sterol metabolic process GO:0016125 166 94 0,000 0,22061431 0,22188586 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,22061431 0,22179455 ! regulation of membrane potential GO:0042391 179 94 0,000 0,22061431 0,22170331 ! regulation of defense response GO:0031347 171 95 0,000 0,22268094 0,22368814 ! nucleosome organization GO:0034728 143 95 0,000 0,22268094 0,2235962 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,22268094 0,22350433 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,22268094 0,22341255 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,22268094 0,22332083 ! sex differentiation GO:0007548 171 96 0,000 0,22474216 0,22529548 ! regulation of T cell activation GO:0050863 175 96 0,000 0,22474216 0,22520307 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,22679797 0,22716992 ! transcription initiation GO:0006352 171 97 0,000 0,22679797 0,22707682 ! forebrain development GO:0030900 210 98 0,000 0,22884838 0,22903588 ! mRNA transport GO:0051028 185 100 0,000 0,23293308 0,23302847 ! hormone metabolic process GO:0042445 171 100 0,000 0,23293308 0,23293308