pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/578-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 6,000 2,586E-08 6,318E-05 ! negative regulation of ligase activity GO:0051352 116 68 6,000 2,872E-08 3,508E-05 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 6,000 2,872E-08 2,339E-05 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 6,000 4,298E-08 2,625E-05 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 6,000 8,232E-08 4,022E-05 ! regulation of ligase activity GO:0051340 147 84 6,000 1,262E-07 5,138E-05 ! tube morphogenesis GO:0035239 194 89 6,000 1,883E-07 6,572E-05 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 6,000 2,55E-07 7,786E-05 GO:0010498|proteasomal protein catabolic process, ! glial cell migration GO:0008347 10 5 2,000 9,404E-07 2,553E-04 ! cell cycle checkpoint GO:0000075 145 71 5,000 9,493E-07 2,319E-04 ! mitotic cell cycle checkpoint GO:0007093 76 39 4,000 9,679E-07 2,15E-04 ! nuclear migration GO:0007097 13 6 2,000 1,875E-06 3,816E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 1,875E-06 3,523E-04 GO:0031272|regulation of pseudopodium assembly, ! branching morphogenesis of a tube GO:0048754 102 45 4,000 2,009E-06 3,505E-04 ! response to hypoxia GO:0001666 178 81 5,000 2,071E-06 3,373E-04 ! response to oxygen levels GO:0070482 183 83 5,000 2,391E-06 3,65E-04 ! ureteric bud development GO:0001657 50 22 3,000 2,923E-06 4,201E-04 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 4,000 4,164E-06 5,652E-04 ! morphogenesis of a branching structure GO:0001763 116 52 4,000 4,164E-06 5,354E-04 ! epithelial tube morphogenesis GO:0060562 114 54 4,000 5,03E-06 6,144E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 5,213E-06 6,065E-04 ! regulation of focal adhesion formation GO:0051893 23 8 2,000 5,213E-06 5,789E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 5,213E-06 5,537E-04 ! RNA elongation GO:0006354 90 56 4,000 6,03E-06 6,138E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 7,794E-06 7,616E-04 ! macrophage differentiation GO:0030225 15 9 2,000 7,794E-06 7,323E-04 ! negative regulation of protein complex assembly GO:0031333 68 30 3,000 1,064E-05 9,63E-04 ! regulation of phosphatase activity GO:0010921 28 10 2,000 1,11E-05 9,681E-04 ! SMAD protein nuclear translocation GO:0007184 21 10 2,000 1,11E-05 9,348E-04 ! spindle organization GO:0007051 50 32 3,000 1,387E-05 1,129E-03 ! metanephros development GO:0001656 81 32 3,000 1,387E-05 1,093E-03 ! negative regulation of proteolysis GO:0045861 25 11 2,000 1,521E-05 1,161E-03 ! adult heart development GO:0007512 16 11 2,000 1,521E-05 1,126E-03 ! positive regulation of leukocyte migration GO:0002687 28 11 2,000 1,521E-05 1,093E-03 ! nucleus localization GO:0051647 22 11 2,000 1,521E-05 1,061E-03 ! lung development GO:0030324 165 69 4,000 1,691E-05 1,148E-03 ! urogenital system development GO:0001655 149 69 4,000 1,691E-05 1,117E-03 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 2,000 2,021E-05 1,299E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 2,021E-05 1,266E-03 ! regulation of leukocyte migration GO:0002685 29 12 2,000 2,021E-05 1,234E-03 ! respiratory tube development GO:0030323 171 72 4,000 2,082E-05 1,241E-03 ! mitotic sister chromatid segregation GO:0000070 63 36 3,000 2,239E-05 1,302E-03 ! acute inflammatory response GO:0002526 118 74 4,000 2,38E-05 1,352E-03 ! respiratory system development GO:0060541 175 74 4,000 2,38E-05 1,321E-03 ! sister chromatid segregation GO:0000819 65 37 3,000 2,502E-05 1,358E-03 ! phosphoinositide-mediated signaling GO:0048015 141 75 4,000 2,54E-05 1,349E-03 ! positive regulation of cell growth GO:0030307 24 13 2,000 2,618E-05 1,361E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 3,321E-05 1,69E-03 GO:0060675|ureteric bud morphogenesis, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 4,000 3,688E-05 1,839E-03 ! mesenchymal cell development GO:0014031 94 41 3,000 3,781E-05 1,848E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of GTPase activity GO:0043547 43 15 2,000 4,137E-05 1,982E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 4,137E-05 1,944E-03 ! positive regulation of cell size GO:0045793 29 16 2,000 5,074E-05 2,339E-03 ! regulation of dephosphorylation GO:0035303 43 16 2,000 5,074E-05 2,296E-03 ! filopodium assembly GO:0046847 42 17 2,000 6,141E-05 2,728E-03 ! complement activation, alternative pathway GO:0006957 19 17 2,000 6,141E-05 2,679E-03 ! regulation of cell adhesion GO:0030155 241 92 4,000 6,798E-05 2,914E-03 ! negative regulation of protein catabolic process GO:0042177 42 18 2,000 7,344E-05 3,094E-03 ! detection of bacterium GO:0016045 22 18 2,000 7,344E-05 3,041E-03 ! microspike assembly GO:0030035 46 18 2,000 7,344E-05 2,99E-03 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 2,000 8,692E-05 3,481E-03 ! transcription initiation GO:0006352 171 97 4,000 8,746E-05 3,446E-03 ! positive regulation of ossification GO:0045778 50 20 2,000 1,019E-04 3,952E-03 ! positive regulation of bone remodeling GO:0046852 54 22 2,000 1,368E-04 5,22E-03 GO:0034105|positive regulation of tissue remodeling, ! positive regulation of locomotion GO:0040017 44 22 2,000 1,368E-04 5,14E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,393E-04 5,157E-03 ! regulation of bone remodeling GO:0046850 143 57 3,000 1,393E-04 5,08E-03 ! heart morphogenesis GO:0003007 105 57 3,000 1,393E-04 5,005E-03 ! nucleotide-excision repair GO:0006289 91 57 3,000 1,393E-04 4,933E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 1,491E-04 5,204E-03 ! regulation of tissue remodeling GO:0034103 146 58 3,000 1,491E-04 5,131E-03 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 2,000 1,567E-04 5,318E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 1,567E-04 5,245E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 2,000 1,567E-04 5,174E-03 GO:0010810|regulation of cell-substrate adhesion, ! kidney development GO:0001822 133 60 3,000 1,702E-04 5,543E-03 ! detection of biotic stimulus GO:0009595 34 24 2,000 1,785E-04 5,739E-03 ! negative regulation of catabolic process GO:0009895 52 24 2,000 1,785E-04 5,664E-03 ! positive regulation of cell adhesion GO:0045785 61 24 2,000 1,785E-04 5,591E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 2,022E-04 6,252E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 2,022E-04 6,174E-03 ! regulation of behavior GO:0050795 48 25 2,000 2,022E-04 6,098E-03 ! interaction with host GO:0051701 66 25 2,000 2,022E-04 6,024E-03 ! regulation of protein complex assembly GO:0043254 132 63 3,000 2,057E-04 6,053E-03 ! regulation of mitosis GO:0007088 112 63 3,000 2,057E-04 5,981E-03 GO:0051783|regulation of nuclear division, ! negative regulation of protein ubiquitination GO:0031397 10 5 1,000 2,071E-04 5,953E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,071E-04 5,884E-03 ! cell adhesion mediated by integrin GO:0033627 10 5 1,000 2,071E-04 5,816E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 1,000 2,071E-04 5,75E-03 ! neutrophil mediated immunity GO:0002446 7 5 1,000 2,071E-04 5,686E-03 ! microvillus organization GO:0032528 8 5 1,000 2,071E-04 5,622E-03 GO:0030033|microvillus assembly, ! positive regulation of chemokine production GO:0032722 8 5 1,000 2,071E-04 5,561E-03 ! enteric nervous system development GO:0048484 8 5 1,000 2,071E-04 5,5E-03 ! muscle cell proliferation GO:0033002 12 5 1,000 2,071E-04 5,441E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 2,071E-04 5,383E-03 GO:0042634|regulation of hair cycle, ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,071E-04 5,327E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 2,071E-04 5,271E-03 GO:0051930|regulation of sensory perception of pain, ! stem cell division GO:0017145 11 5 1,000 2,071E-04 5,217E-03 GO:0048103|somatic stem cell division, ! positive regulation of cell motion GO:0051272 157 65 3,000 2,321E-04 5,786E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 2,554E-04 6,302E-03 ! chromosome segregation GO:0007059 127 67 3,000 2,609E-04 6,373E-03 ! myeloid cell differentiation GO:0030099 126 67 3,000 2,609E-04 6,31E-03 ! cell projection assembly GO:0030031 138 68 3,000 2,762E-04 6,615E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 2,851E-04 6,762E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 3,000 2,922E-04 6,863E-03 ! neurofilament cytoskeleton organization GO:0060052 12 6 1,000 3,098E-04 7,207E-03 ! erythrocyte maturation GO:0043249 8 6 1,000 3,098E-04 7,139E-03 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 3,098E-04 7,072E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 3,098E-04 7,007E-03 ! interaction with symbiont GO:0051702 14 6 1,000 3,098E-04 6,943E-03 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 1,000 3,098E-04 6,879E-03 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 3,098E-04 6,817E-03 ! salivary gland morphogenesis GO:0007435 14 6 1,000 3,098E-04 6,757E-03 ! activation of Ras GTPase activity GO:0032856 13 6 1,000 3,098E-04 6,697E-03 GO:0032862|activation of Rho GTPase activity, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 3,000 3,44E-04 7,372E-03 ! regulation of MAPKKK cascade GO:0043408 157 72 3,000 3,44E-04 7,308E-03 ! acute-phase response GO:0006953 50 30 2,000 3,509E-04 7,391E-03 ! organelle localization GO:0051640 155 74 3,000 3,82E-04 7,977E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 4,324E-04 8,951E-03 ! mRNA stabilization GO:0048255 18 7 1,000 4,324E-04 8,876E-03 GO:0043489|RNA stabilization, ! spindle checkpoint GO:0031577 16 7 1,000 4,324E-04 8,802E-03 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 4,324E-04 8,729E-03 ! negative regulation of focal adhesion formation GO:0051895 21 7 1,000 4,324E-04 8,658E-03 ! transcription from RNA polymerase I promoter GO:0006360 14 7 1,000 4,324E-04 8,587E-03 ! anaphase GO:0051322 18 7 1,000 4,324E-04 8,518E-03 GO:0000090|mitotic anaphase, ! negative regulation of nuclear division GO:0051784 15 7 1,000 4,324E-04 8,45E-03 GO:0045839|negative regulation of mitosis, ! dopamine biosynthetic process GO:0042416 18 7 1,000 4,324E-04 8,383E-03 ! positive regulation of ligase activity GO:0051351 130 77 3,000 4,445E-04 8,551E-03 ! steroid biosynthetic process GO:0006694 146 79 3,000 4,901E-04 9,353E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 5,103E-04 9,665E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 3,000 5,14E-04 9,66E-03 ! protein import into nucleus GO:0006606 174 82 3,000 5,644E-04 0,01052598 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 5,747E-04 0,01063692 ! T-helper 1 type immune response GO:0042088 12 8 1,000 5,747E-04 0,01055694 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 5,747E-04 0,01047816 ! positive regulation of insulin secretion GO:0032024 17 8 1,000 5,747E-04 0,01040054 ! regulation of vascular permeability GO:0043114 12 8 1,000 5,747E-04 0,01032407 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 5,747E-04 0,01024871 ! positive regulation of epidermis development GO:0045684 13 8 1,000 5,747E-04 0,01017444 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 1,000 5,747E-04 0,01010125 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 5,747E-04 0,01002909 ! nuclear import GO:0051170 177 83 3,000 5,909E-04 0,01023822 ! positive regulation of cell development GO:0010720 85 36 2,000 6,049E-04 0,0104061 ! regulation of proteolysis GO:0030162 77 36 2,000 6,049E-04 0,01033333 ! response to nutrient GO:0007584 135 84 3,000 6,183E-04 0,01048889 ! tissue remodeling GO:0048771 78 37 2,000 6,56E-04 0,0110528 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 7,367E-04 0,01232738 GO:0010469|regulation of receptor activity, ! induction of positive chemotaxis GO:0050930 17 9 1,000 7,367E-04 0,01224352 ! glycine catabolic process GO:0006546 15 9 1,000 7,367E-04 0,01216079 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 1,000 7,367E-04 0,01207917 ! retinol metabolic process GO:0042572 20 9 1,000 7,367E-04 0,01199865 ! erythrocyte development GO:0048821 17 9 1,000 7,367E-04 0,01191919 ! mitochondrion localization GO:0051646 18 9 1,000 7,367E-04 0,01184077 ! protein localization in nucleus GO:0034504 192 89 3,000 7,686E-04 0,0122725 ! regulation of cell cycle process GO:0010564 161 90 3,000 8,015E-04 0,01271476 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 2,000 8,258E-04 0,01301577 GO:0006956|complement activation, ! development of primary female sexual characteristics GO:0046545 80 40 2,000 8,258E-04 0,01293234 GO:0046660|female sex differentiation, ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 8,88E-04 0,01381798 ! gliogenesis GO:0042063 91 41 2,000 8,88E-04 0,01373053 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 8,88E-04 0,01364417 ! embryonic epithelial tube formation GO:0001838 85 41 2,000 8,88E-04 0,0135589 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 9,062E-04 0,01375009 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 9,181E-04 0,01384549 ! positive regulation of heart contraction GO:0045823 17 10 1,000 9,181E-04 0,01376055 ! lung alveolus development GO:0048286 26 10 1,000 9,181E-04 0,01367664 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 9,181E-04 0,01359375 ! regulation of stress fiber formation GO:0051492 34 10 1,000 9,181E-04 0,01351186 ! regulation of bone resorption GO:0045124 25 10 1,000 9,181E-04 0,01343095 ! regulation of gliogenesis GO:0014013 23 10 1,000 9,181E-04 0,01335101 GO:0045685|regulation of glial cell differentiation, ! regulation of insulin receptor signaling pathway GO:0046626 22 10 1,000 9,181E-04 0,01327201 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 1,000 9,181E-04 0,01319394 ! salivary gland development GO:0007431 28 10 1,000 9,181E-04 0,01311678 ! serine family amino acid catabolic process GO:0009071 18 10 1,000 9,181E-04 0,01304052 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 9,181E-04 0,01296514 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 9,181E-04 0,01289063 ! negative regulation of multicellular organismal process GO:0051241 174 95 3,000 9,811E-04 0,01369568 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 1,092E-03 0,01516082 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 1,092E-03 0,01507517 ! leukocyte differentiation GO:0002521 232 98 3,000 1,101E-03 0,01511672 ! blood vessel remodeling GO:0001974 30 11 1,000 1,119E-03 0,015269 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,119E-03 0,01518418 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,119E-03 0,01510029 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,119E-03 0,01501732 ! positive regulation of peptide secretion GO:0002793 24 11 1,000 1,119E-03 0,01493526 ! positive regulation of Rho GTPase activity GO:0032321 31 11 1,000 1,119E-03 0,01485409 ! regulation of actin filament bundle formation GO:0032231 37 11 1,000 1,119E-03 0,01477379 ! cardiac cell differentiation GO:0035051 36 11 1,000 1,119E-03 0,01469436 ! regulation of embryonic development GO:0045995 35 11 1,000 1,119E-03 0,01461579 ! positive regulation of immune response GO:0050778 175 100 3,000 1,187E-03 0,01542711 ! response to insulin stimulus GO:0032868 98 47 2,000 1,324E-03 0,0171121 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 1,338E-03 0,01721005 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,338E-03 0,01711995 ! entry into host cell GO:0030260 34 12 1,000 1,338E-03 0,01703078 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of interleukin-8 production GO:0032677 22 12 1,000 1,338E-03 0,01694254 ! histone acetylation GO:0016573 27 12 1,000 1,338E-03 0,0168552 ! autonomic nervous system development GO:0048483 24 12 1,000 1,338E-03 0,01676877 ! zymogen activation GO:0031638 18 12 1,000 1,338E-03 0,01668321 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,338E-03 0,01659853 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,338E-03 0,01651469 ! defense response to fungus GO:0050832 15 12 1,000 1,338E-03 0,01643171 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,407E-03 0,01719129 ! response to calcium ion GO:0051592 94 49 2,000 1,494E-03 0,01816041 ! regulation of chemokine production GO:0032642 18 13 1,000 1,577E-03 0,01907332 ! cartilage condensation GO:0001502 22 13 1,000 1,577E-03 0,01897936 ! pseudouridine synthesis GO:0001522 19 13 1,000 1,577E-03 0,01888632 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 1,577E-03 0,0187942 ! exocrine system development GO:0035272 34 13 1,000 1,577E-03 0,01870296 ! membrane protein proteolysis GO:0033619 33 13 1,000 1,577E-03 0,01861261 GO:0006509|membrane protein ectodomain proteolysis, ! gland morphogenesis GO:0022612 31 13 1,000 1,577E-03 0,01852313 ! regulation of epidermis development GO:0045682 19 13 1,000 1,577E-03 0,0184345 ! spleen development GO:0048536 24 13 1,000 1,577E-03 0,01834672 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,577E-03 0,01825976 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 1,577E-03 0,01817363 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,584E-03 0,01817019 ! regulation of ossification GO:0030278 123 50 2,000 1,584E-03 0,01808528 ! regulation of cell projection organization GO:0031344 135 51 2,000 1,678E-03 0,01906229 ! viral infectious cycle GO:0019058 104 51 2,000 1,678E-03 0,01897404 ! response to estrogen stimulus GO:0043627 98 52 2,000 1,774E-03 0,01997593 ! morphogenesis of embryonic epithelium GO:0016331 106 52 2,000 1,774E-03 0,0198843 ! retina development in camera-type eye GO:0060041 28 14 1,000 1,834E-03 0,02046313 ! hair follicle morphogenesis GO:0031069 27 14 1,000 1,834E-03 0,02037011 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 1,834E-03 0,02027794 ! positive regulation of Ras GTPase activity GO:0032320 42 14 1,000 1,834E-03 0,0201866 ! positive regulation of bone mineralization GO:0030501 32 14 1,000 1,834E-03 0,02009607 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 1,834E-03 0,02000636 ! regulation of RNA stability GO:0043487 33 14 1,000 1,834E-03 0,01991744 ! cartilage development GO:0051216 99 53 2,000 1,875E-03 0,02026331 ! positive regulation of growth GO:0045927 96 53 2,000 1,875E-03 0,02017404 ! regulation of cell shape GO:0008360 142 54 2,000 1,978E-03 0,021196 ! cell maturation GO:0048469 107 55 2,000 2,085E-03 0,02224639 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,11E-03 0,02241446 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,11E-03 0,02231743 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 2,11E-03 0,02222123 ! positive regulation of biomineral formation GO:0070169 33 15 1,000 2,11E-03 0,02212586 ! dopamine metabolic process GO:0042417 35 15 1,000 2,11E-03 0,02203131 ! cell killing GO:0001906 32 15 1,000 2,11E-03 0,02193756 ! regulation of protein catabolic process GO:0042176 126 56 2,000 2,196E-03 0,02273224 ! regulation of protein ubiquitination GO:0031396 28 16 1,000 2,404E-03 0,0247852 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 2,404E-03 0,02468106 ! startle response GO:0001964 28 16 1,000 2,404E-03 0,02457779 ! intermediate filament-based process GO:0045103 36 16 1,000 2,404E-03 0,02447538 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 1,000 2,404E-03 0,02437382 ! tissue regeneration GO:0042246 27 16 1,000 2,404E-03 0,02427311 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,404E-03 0,02417322 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,404E-03 0,02407415 ! negative regulation of immune response GO:0050777 38 16 1,000 2,404E-03 0,02397588 ! establishment of organelle localization GO:0051656 122 59 2,000 2,55E-03 0,02532053 ! DNA catabolic process GO:0006308 94 60 2,000 2,675E-03 0,0264567 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,717E-03 0,02676331 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,717E-03 0,02665583 ! cardiac muscle tissue development GO:0048738 34 17 1,000 2,717E-03 0,0265492 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 2,717E-03 0,02644343 ! genitalia development GO:0048806 32 17 1,000 2,717E-03 0,0263385 ! neutrophil chemotaxis GO:0030593 29 17 1,000 2,717E-03 0,02623439 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 1,000 2,717E-03 0,02613111 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 2,717E-03 0,02602863 ! viral reproductive process GO:0022415 132 62 2,000 2,937E-03 0,02802411 ! regulation of homeostatic process GO:0032844 148 62 2,000 2,937E-03 0,02791507 ! patterning of blood vessels GO:0001569 43 18 1,000 3,047E-03 0,02885479 ! epidermis morphogenesis GO:0048730 43 18 1,000 3,047E-03 0,02874338 ! glycine metabolic process GO:0006544 30 18 1,000 3,047E-03 0,02863283 ! response to retinoic acid GO:0032526 31 18 1,000 3,047E-03 0,02852312 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 3,047E-03 0,02841426 ! neural crest cell migration GO:0001755 41 18 1,000 3,047E-03 0,02830622 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 3,047E-03 0,028199 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 3,047E-03 0,02809259 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 3,047E-03 0,02798698 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 3,214E-03 0,0294035 ! neuron maturation GO:0042551 46 19 1,000 3,396E-03 0,03095291 ! positive regulation of hormone secretion GO:0046887 35 19 1,000 3,396E-03 0,03083785 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 1,000 3,396E-03 0,03072363 ! response to vitamin A GO:0033189 32 19 1,000 3,396E-03 0,03061026 ! response to lipopolysaccharide GO:0032496 34 19 1,000 3,396E-03 0,03049772 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 3,396E-03 0,03038601 ! response to fungus GO:0009620 26 19 1,000 3,396E-03 0,03027511 ! peptide cross-linking GO:0018149 39 19 1,000 3,396E-03 0,03016502 ! vitamin transport GO:0051180 31 19 1,000 3,396E-03 0,03005573 ! proximal/distal pattern formation GO:0009954 33 19 1,000 3,396E-03 0,02994722 ! embryonic organ morphogenesis GO:0048562 34 19 1,000 3,396E-03 0,0298395 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 3,506E-03 0,0306995 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 3,762E-03 0,03281938 ! protein amino acid acetylation GO:0006473 41 20 1,000 3,762E-03 0,03270258 ! response to vitamin GO:0033273 36 20 1,000 3,762E-03 0,03258662 ! transcription from RNA polymerase III promoter GO:0006383 46 20 1,000 3,762E-03 0,03247147 ! retinoid metabolic process GO:0001523 34 20 1,000 3,762E-03 0,03235713 GO:0016101|diterpenoid metabolic process, ! negative regulation of translation GO:0017148 32 20 1,000 3,762E-03 0,0322436 ! detection of external stimulus GO:0009581 102 68 2,000 3,814E-03 0,03258077 ! viral reproduction GO:0016032 142 68 2,000 3,814E-03 0,03246725 ! adaptive immune response GO:0002250 126 68 2,000 3,814E-03 0,03235451 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 3,974E-03 0,03359587 ! developmental maturation GO:0021700 128 69 2,000 3,974E-03 0,03348002 ! negative regulation of kinase activity GO:0033673 145 70 2,000 4,138E-03 0,03474286 ! activation of immune response GO:0002253 120 70 2,000 4,138E-03 0,03462387 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 4,138E-03 0,0345057 ! lipid phosphorylation GO:0046834 43 21 1,000 4,145E-03 0,03444306 ! ovarian follicle development GO:0001541 39 21 1,000 4,145E-03 0,0343263 ! collagen fibril organization GO:0030199 62 21 1,000 4,145E-03 0,03421034 ! vitamin A metabolic process GO:0006776 35 21 1,000 4,145E-03 0,03409515 ! positive regulation of osteoblast differentiation GO:0045669 52 21 1,000 4,145E-03 0,03398074 ! camera-type eye morphogenesis GO:0048593 47 21 1,000 4,145E-03 0,03386709 ! inactivation of MAPK activity GO:0000188 45 22 1,000 4,546E-03 0,03701826 ! cellular response to starvation GO:0009267 37 22 1,000 4,546E-03 0,03689527 ! terpenoid metabolic process GO:0006721 40 22 1,000 4,546E-03 0,0367731 ! gut development GO:0048565 44 22 1,000 4,546E-03 0,03665174 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 4,546E-03 0,03653118 ! humoral immune response GO:0006959 115 73 2,000 4,655E-03 0,03728832 ! negative regulation of transferase activity GO:0051348 155 74 2,000 4,836E-03 0,03860801 ! gluconeogenesis GO:0006094 38 23 1,000 4,964E-03 0,03950057 ! viral genome replication GO:0019079 44 23 1,000 4,964E-03 0,03937232 ! regeneration GO:0031099 42 23 1,000 4,964E-03 0,0392449 ! regulation of Rho GTPase activity GO:0032319 56 23 1,000 4,964E-03 0,03911831 ! regulation of bone mineralization GO:0030500 54 23 1,000 4,964E-03 0,03899252 ! negative regulation of cytokine production GO:0001818 41 23 1,000 4,964E-03 0,03886755 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 4,964E-03 0,03874337 ! reproductive structure development GO:0048608 131 75 2,000 5,021E-03 0,0390617 ! eye development GO:0001654 155 75 2,000 5,021E-03 0,03893769 ! regulation of actin cytoskeleton organization GO:0032956 167 76 2,000 5,21E-03 0,04027522 ! protein amino acid O-linked glycosylation GO:0006493 45 24 1,000 5,399E-03 0,0416071 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 5,399E-03 0,04147626 ! barbed-end actin filament capping GO:0051016 58 24 1,000 5,399E-03 0,04134624 GO:0051693|actin filament capping, ! platelet activation GO:0030168 41 24 1,000 5,399E-03 0,04121704 ! regulation of catabolic process GO:0009894 173 77 2,000 5,403E-03 0,04111807 ! blood coagulation GO:0007596 151 79 2,000 5,802E-03 0,0440187 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 2,000 5,802E-03 0,04388242 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 5,802E-03 0,04374698 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 5,851E-03 0,04397972 ! vasculogenesis GO:0001570 49 25 1,000 5,851E-03 0,04384481 ! regulation of insulin secretion GO:0050796 42 25 1,000 5,851E-03 0,04371073 ! regulation of biomineral formation GO:0070167 56 25 1,000 5,851E-03 0,04357747 ! positive regulation of protein secretion GO:0050714 41 25 1,000 5,851E-03 0,04344501 ! liver development GO:0001889 55 25 1,000 5,851E-03 0,04331336 ! activation of protein kinase activity GO:0032147 170 80 2,000 6,008E-03 0,04434239 ! development of primary sexual characteristics GO:0045137 143 80 2,000 6,008E-03 0,04420883 ! negative regulation of organelle organization GO:0010639 181 80 2,000 6,008E-03 0,04407607 ! initiation of viral infection GO:0019059 60 26 1,000 6,319E-03 0,04622201 ! pyruvate metabolic process GO:0006090 43 26 1,000 6,319E-03 0,04608404 ! molting cycle process GO:0022404 52 26 1,000 6,319E-03 0,04594688 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 6,319E-03 0,04581054 ! digestive system process GO:0022600 49 26 1,000 6,319E-03 0,04567501 ! neural crest cell development GO:0014032 59 26 1,000 6,319E-03 0,04554027 GO:0014033|neural crest cell differentiation, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 6,319E-03 0,04540633 ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 6,319E-03 0,04527317 ! neural tube closure GO:0001843 58 26 1,000 6,319E-03 0,0451408 GO:0060606|tube closure, ! cell-substrate adhesion GO:0031589 189 82 2,000 6,433E-03 0,04581847 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 6,804E-03 0,04832352 ! negative regulation of actin filament polymerization GO:0030837 61 27 1,000 6,804E-03 0,04818345 ! tube lumen formation GO:0035148 59 27 1,000 6,804E-03 0,04804419 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 6,804E-03 0,04790573 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 6,804E-03 0,04776807 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 6,804E-03 0,0476312 ! response to starvation GO:0042594 47 27 1,000 6,804E-03 0,04749511 ! cellular response to nutrient levels GO:0031669 45 27 1,000 6,804E-03 0,0473598 ! fat-soluble vitamin metabolic process GO:0006775 42 27 1,000 6,804E-03 0,04722525 ! response to metal ion GO:0010038 158 84 2,000 6,876E-03 0,04758325 ! hemostasis GO:0007599 165 85 2,000 7,103E-03 0,04902154 ! regulation of neuron differentiation GO:0045664 187 85 2,000 7,103E-03 0,04888345 ! protein amino acid acylation GO:0043543 59 28 1,000 7,306E-03 0,05013604 ! negative regulation of protein modification process GO:0031400 66 28 1,000 7,306E-03 0,0499956 ! base-excision repair GO:0006284 41 28 1,000 7,306E-03 0,04985595 ! negative regulation of protein polymerization GO:0032272 63 28 1,000 7,306E-03 0,04971707 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 7,824E-03 0,05309218 ! catechol metabolic process GO:0009712 55 29 1,000 7,824E-03 0,05294511 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! primary neural tube formation GO:0014020 61 29 1,000 7,824E-03 0,05279885 ! regulation of peptide secretion GO:0002791 52 29 1,000 7,824E-03 0,0526534 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 7,824E-03 0,05250875 ! response to organic cyclic substance GO:0014070 58 29 1,000 7,824E-03 0,05236489 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 7,824E-03 0,05222182 ! somitogenesis GO:0001756 52 29 1,000 7,824E-03 0,05207952 ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 8,06E-03 0,05350404 ! response to inorganic substance GO:0010035 173 90 2,000 8,31E-03 0,05501603 ! response to unfolded protein GO:0006986 139 90 2,000 8,31E-03 0,05486734 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 8,357E-03 0,05503281 ! phenol metabolic process GO:0018958 56 30 1,000 8,357E-03 0,05488487 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 8,357E-03 0,05473773 ! negative regulation of protein kinase cascade GO:0010741 72 30 1,000 8,357E-03 0,05459137 ! tissue homeostasis GO:0001894 50 30 1,000 8,357E-03 0,05444579 GO:0048871|multicellular organismal homeostasis, ! ossification GO:0001503 205 91 2,000 8,565E-03 0,05564739 ! bone development GO:0060348 206 92 2,000 8,824E-03 0,05718047 ! ovulation cycle process GO:0022602 55 31 1,000 8,907E-03 0,05756616 ! erythrocyte differentiation GO:0030218 62 31 1,000 8,907E-03 0,05741427 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 8,907E-03 0,05726318 ! eye morphogenesis GO:0048592 65 31 1,000 8,907E-03 0,05711289 ! response to mechanical stimulus GO:0009612 60 32 1,000 9,472E-03 0,06057936 ! hexose biosynthetic process GO:0019319 53 32 1,000 9,472E-03 0,06042119 ! ovulation cycle GO:0042698 57 32 1,000 9,472E-03 0,06026385 ! BMP signaling pathway GO:0030509 71 32 1,000 9,472E-03 0,06010732 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 9,63E-03 0,06094558 ! sex differentiation GO:0007548 171 96 2,000 9,907E-03 0,06254127 ! response to protein stimulus GO:0051789 158 96 2,000 9,907E-03 0,06238008 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 0,01005351 0,06313809 ! leukocyte chemotaxis GO:0030595 55 33 1,000 0,01005351 0,0629762 GO:0060326|cell chemotaxis, ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 0,01047662 0,0654588 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 0,01047662 0,06529182 ! negative regulation of MAP kinase activity GO:0043407 78 34 1,000 0,01064996 0,06620316 ! serine family amino acid metabolic process GO:0009069 56 34 1,000 0,01064996 0,06603513 ! adult locomotory behavior GO:0008344 62 34 1,000 0,01064996 0,06586795 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01126169 0,06947553 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 0,01126169 0,06930053 ! placenta development GO:0001890 53 35 1,000 0,01126169 0,06912641 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 0,01188856 0,07279138 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01188856 0,0726094 ! embryonic organ development GO:0048568 67 36 1,000 0,01188856 0,07242833 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01188856 0,07224816 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01253042 0,07595986 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01253042 0,07577184 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01253042 0,07558475 ! odontogenesis GO:0042476 74 37 1,000 0,01253042 0,07539858 ! actomyosin structure organization GO:0031032 68 37 1,000 0,01253042 0,07521332 ! female gonad development GO:0008585 71 37 1,000 0,01253042 0,07502898 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01318712 0,07876806 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01318712 0,07857594 ! neural tube formation GO:0001841 79 38 1,000 0,01318712 0,07838476 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,01385851 0,08217558 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01385851 0,0819766 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,01385851 0,08177859 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,01385851 0,08158154 ! RNA export from nucleus GO:0006405 61 41 1,000 0,01524477 0,08952638 ! regulation of hormone secretion GO:0046883 69 41 1,000 0,01524477 0,08931169 ! RNA modification GO:0009451 64 41 1,000 0,01524477 0,08909802 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,01595935 0,09305179 ! T cell differentiation GO:0030217 93 42 1,000 0,01595935 0,09283023 ! regulation of protein secretion GO:0050708 77 42 1,000 0,01595935 0,09260973 ! response to xenobiotic stimulus GO:0009410 63 42 1,000 0,01595935 0,09239028 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01668804 0,09638036 GO:0090047|positive regulation of transcription regulator activity, ! segmentation GO:0035282 78 43 1,000 0,01668804 0,09615305 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 0,0174307 0,10019578 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,0174307 0,09996058 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,01818718 0,10405455 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01818718 0,10381143 ! B cell differentiation GO:0030183 124 45 1,000 0,01818718 0,10356945 ! developmental growth GO:0048589 88 45 1,000 0,01818718 0,10332859 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01818718 0,10308885 ! regulation of actin filament polymerization GO:0030833 99 46 1,000 0,01895735 0,10720558 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 1,000 0,01895735 0,10695799 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01895735 0,10671154 ! leukocyte migration GO:0050900 75 46 1,000 0,01895735 0,10646623 ! cell growth GO:0016049 90 46 1,000 0,01895735 0,10622204 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01895735 0,10597897 ! neural tube development GO:0021915 91 47 1,000 0,01974106 0,11010825 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,02053818 0,11429333 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02053818 0,11403357 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02053818 0,11377499 ! protein homooligomerization GO:0051260 84 49 1,000 0,02134856 0,11799669 ! activation of caspase activity GO:0006919 95 50 1,000 0,02217208 0,12227174 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02217208 0,12199636 ! positive regulation of cytokine production GO:0001819 94 50 1,000 0,02217208 0,12172221 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02272125 0,12445745 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02272125 0,12417903 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02272125 0,12390184 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02272125 0,12362589 ! neuron fate determination GO:0048664 7 5 0,000 0,02272125 0,12335117 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02272125 0,12307766 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02272125 0,12280536 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02272125 0,12253427 ! polyol transport GO:0015791 12 5 0,000 0,02272125 0,12226437 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02272125 0,12199566 ! response to superoxide GO:0000303 10 5 0,000 0,02272125 0,12172812 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02272125 0,12146176 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02272125 0,12119656 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02272125 0,12093252 ! female meiosis GO:0007143 10 5 0,000 0,02272125 0,12066962 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02272125 0,12040786 ! hypothalamus development GO:0021854 9 5 0,000 0,02272125 0,12014724 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02272125 0,11988774 ! cobalt ion transport GO:0006824 11 5 0,000 0,02272125 0,11962936 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02272125 0,1193721 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02272125 0,11911593 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02272125 0,11886087 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02272125 0,11860689 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02272125 0,118354 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02272125 0,11810218 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02272125 0,11785143 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02272125 0,11760175 ! transposition GO:0032196 9 5 0,000 0,02272125 0,11735312 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02272125 0,11710554 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02272125 0,116859 ! negative chemotaxis GO:0050919 16 5 0,000 0,02272125 0,1166135 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02272125 0,11636902 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02272125 0,11612557 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02272125 0,11588314 ! behavioral response to pain GO:0048266 10 5 0,000 0,02272125 0,11564172 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02272125 0,1154013 ! Notch receptor processing GO:0007220 11 5 0,000 0,02272125 0,11516188 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02272125 0,11492345 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02272125 0,114686 ! micturition GO:0060073 9 5 0,000 0,02272125 0,11444954 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02272125 0,11421404 ! copulation GO:0007620 9 5 0,000 0,02272125 0,11397952 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02272125 0,11374595 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02272125 0,11351334 ! bioluminescence GO:0008218 9 5 0,000 0,02272125 0,11328168 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02272125 0,11305097 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02272125 0,11282119 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02272125 0,11259234 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02272125 0,11236442 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02272125 0,11213742 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02272125 0,11191134 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02272125 0,11168617 ! grooming behavior GO:0007625 6 5 0,000 0,02272125 0,1114619 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02272125 0,11123853 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02272125 0,11101605 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02272125 0,11079446 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02272125 0,11057375 ! response to protozoan GO:0001562 13 5 0,000 0,02272125 0,11035393 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02272125 0,11013497 ! lymph vessel development GO:0001945 10 5 0,000 0,02272125 0,10991688 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02272125 0,10969965 ! endochondral ossification GO:0001958 17 5 0,000 0,02272125 0,10948328 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02272125 0,10926776 ! single strand break repair GO:0000012 8 5 0,000 0,02272125 0,10905309 ! parathyroid gland development GO:0060017 14 5 0,000 0,02272125 0,10883926 ! anagen GO:0042640 7 5 0,000 0,02272125 0,10862627 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02272125 0,10841411 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02272125 0,10820278 ! cytokine secretion GO:0050663 15 5 0,000 0,02272125 0,10799227 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02272125 0,10778257 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02272125 0,10757369 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02272125 0,10736562 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02272125 0,10715835 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02272125 0,10695188 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02272125 0,1067462 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02272125 0,10654131 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02272125 0,10633721 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02272125 0,10613389 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02272125 0,10593134 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02272125 0,10572957 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02272125 0,10552856 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02272125 0,10532832 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02272125 0,10512883 ! valine metabolic process GO:0006573 12 5 0,000 0,02272125 0,1049301 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02272125 0,10473212 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02272125 0,10453489 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02272125 0,10433839 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02272125 0,10414264 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02272125 0,10394761 ! polyol catabolic process GO:0046174 9 5 0,000 0,02272125 0,10375332 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02272125 0,10355975 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02272125 0,1033669 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02272125 0,10317477 ! muscle cell migration GO:0014812 8 5 0,000 0,02272125 0,10298335 ! mitochondrial fission GO:0000266 8 5 0,000 0,02272125 0,10279264 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02272125 0,10260263 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02272125 0,10241333 ! mRNA transcription GO:0009299 10 5 0,000 0,02272125 0,10222472 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02272125 0,10203681 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02272125 0,10184959 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02272125 0,10166305 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02272125 0,10147719 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02272125 0,10129202 ! monocyte activation GO:0042117 10 5 0,000 0,02272125 0,10110751 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02272125 0,10092368 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02272125 0,10074052 ! response to food GO:0032094 6 5 0,000 0,02272125 0,10055802 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02272125 0,10037617 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02272125 0,10019499 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02272125 0,10001446 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02272125 0,09983458 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02272125 0,09965534 ! forebrain neuron development GO:0021884 13 5 0,000 0,02272125 0,09947675 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02272125 0,09929879 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02272125 0,09912147 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02272125 0,09894479 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02272125 0,09876873 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02272125 0,09859329 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02272125 0,09841848 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02272125 0,09824429 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02272125 0,09807071 ! lipid glycosylation GO:0030259 7 5 0,000 0,02272125 0,09789775 ! nucleobase transport GO:0015851 6 5 0,000 0,02272125 0,0977254 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02272125 0,09755365 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02272125 0,0973825 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02272125 0,09721195 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02272125 0,097042 ! basic amino acid transport GO:0015802 12 5 0,000 0,02272125 0,09687264 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02272125 0,09670388 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02272125 0,09653569 ! actin nucleation GO:0045010 11 5 0,000 0,02272125 0,0963681 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02272125 0,09620108 ! depurination GO:0045007 5 5 0,000 0,02272125 0,09603464 ! depyrimidination GO:0045008 10 5 0,000 0,02272125 0,09586878 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02272125 0,09570349 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02272125 0,09553877 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02272125 0,09537461 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02272125 0,09521102 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02272125 0,09504799 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02272125 0,09488551 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02272125 0,09472359 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02272125 0,09456222 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02272125 0,0944014 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02272125 0,09424113 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02272125 0,0940814 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02272125 0,09392221 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02272125 0,09376355 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02272125 0,09360544 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02272125 0,09344785 ! response to arsenic GO:0046685 11 5 0,000 0,02272125 0,0932908 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02272125 0,09313427 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02272125 0,09297827 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02272125 0,09282278 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02272125 0,09266782 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02272125 0,09251337 ! response to mercury ion GO:0046689 8 5 0,000 0,02272125 0,09235944 ! response to cadmium ion GO:0046686 7 5 0,000 0,02272125 0,09220602 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02272125 0,09205311 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02272125 0,0919007 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02272125 0,0917488 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02272125 0,0915974 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02272125 0,0914465 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02272125 0,09129609 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02272125 0,09114618 ! decidualization GO:0046697 11 5 0,000 0,02272125 0,09099676 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02272125 0,09084783 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02272125 0,09069939 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02272125 0,09055143 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02272125 0,09040395 ! embryonic cleavage GO:0040016 6 5 0,000 0,02272125 0,09025695 ! peroxisome fission GO:0016559 5 5 0,000 0,02272125 0,09011043 ! histone demethylation GO:0016577 13 5 0,000 0,02272125 0,08996438 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02272125 0,08981881 ! mitotic recombination GO:0006312 9 5 0,000 0,02272125 0,08967371 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02272125 0,08952907 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02272125 0,0893849 ! metaphase plate congression GO:0051310 7 5 0,000 0,02272125 0,0892412 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02272125 0,08909795 GO:0032374|regulation of cholesterol transport, ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02272125 0,08895517 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02272125 0,08881284 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02272125 0,08867097 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02272125 0,08852954 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02272125 0,08838857 ! B cell homeostasis GO:0001782 13 5 0,000 0,02272125 0,08824805 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02272125 0,08810798 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02272125 0,08796834 ! metaphase GO:0051323 11 5 0,000 0,02272125 0,08782915 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02272125 0,0876904 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02272125 0,08755209 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02272125 0,08741421 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02272125 0,08727677 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02272125 0,08713976 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02272125 0,08700317 ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02272125 0,08686702 ! response to redox state GO:0051775 6 5 0,000 0,02272125 0,08673129 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02272125 0,08659598 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02272125 0,0864611 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02272125 0,08632663 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02272125 0,08619258 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02272125 0,08605895 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02272125 0,08592573 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02272125 0,08579293 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02272125 0,08566053 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02272125 0,08552854 ! striatum development GO:0021756 14 5 0,000 0,02272125 0,08539696 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02272125 0,08526578 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02272125 0,08513501 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02272125 0,08500463 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02272125 0,08487466 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02272125 0,08474508 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02272125 0,08461589 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02272125 0,0844871 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02272125 0,0843587 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02272125 0,08423069 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02272125 0,08410307 ! neuroprotection GO:0043526 8 5 0,000 0,02272125 0,08397583 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02272125 0,08384898 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02272125 0,08372251 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02272125 0,08359642 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02272125 0,08347071 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02272125 0,08334538 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02272125 0,08322043 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02272125 0,08309585 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02272125 0,08297164 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02272125 0,0828478 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02272125 0,08272433 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02272125 0,08260123 ! spindle assembly GO:0051225 6 5 0,000 0,02272125 0,08247849 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02272125 0,08235612 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02272125 0,08223411 ! protein palmitoylation GO:0018345 12 5 0,000 0,02272125 0,08211246 ! drug metabolic process GO:0017144 7 5 0,000 0,02272125 0,08199117 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02272125 0,08187024 ! organ regeneration GO:0031100 7 5 0,000 0,02272125 0,08174967 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02272125 0,08162945 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02272125 0,08150958 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,02300859 0,08241932 ! positive regulation of binding GO:0051099 88 52 1,000 0,02385795 0,08533672 ! Notch signaling pathway GO:0007219 111 52 1,000 0,02385795 0,08521196 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02385795 0,08508756 ! histone modification GO:0016570 104 52 1,000 0,02385795 0,08496353 ! chromatin remodeling GO:0006338 122 53 1,000 0,02472005 0,0879055 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 1,000 0,02472005 0,08777773 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02472005 0,08765033 ! regulation of translational initiation GO:0006446 87 54 1,000 0,02559474 0,0906202 ! neuromuscular process GO:0050905 107 54 1,000 0,02559474 0,09048906 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,02559474 0,09035829 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,02559474 0,09022791 ! covalent chromatin modification GO:0016569 115 54 1,000 0,02559474 0,0900979 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,02648188 0,09308668 ! regulation of protein polymerization GO:0032271 117 55 1,000 0,02648188 0,09295293 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02720355 0,09534904 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02720355 0,09521244 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02720355 0,09507623 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02720355 0,0949404 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02720355 0,09480497 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02720355 0,09466992 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02720355 0,09453525 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02720355 0,09440097 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02720355 0,09426707 ! response to oxygen radical GO:0000305 11 6 0,000 0,02720355 0,09413354 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02720355 0,0940004 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02720355 0,09386763 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02720355 0,09373524 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02720355 0,09360321 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02720355 0,09347156 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02720355 0,09334028 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02720355 0,09320937 ! forebrain regionalization GO:0021871 9 6 0,000 0,02720355 0,09307883 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02720355 0,09294865 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02720355 0,09281883 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02720355 0,09268937 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02720355 0,09256028 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02720355 0,09243155 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02720355 0,09230317 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02720355 0,09217515 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02720355 0,09204748 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02720355 0,09192017 ! malate metabolic process GO:0006108 13 6 0,000 0,02720355 0,09179321 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02720355 0,0916666 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02720355 0,09154033 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02720355 0,09141442 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02720355 0,09128885 ! protein refolding GO:0042026 15 6 0,000 0,02720355 0,09116362 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02720355 0,09103874 ! opsonization GO:0008228 8 6 0,000 0,02720355 0,0909142 ! mating behavior GO:0007617 7 6 0,000 0,02720355 0,09079 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02720355 0,09066614 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02720355 0,09054262 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02720355 0,09041943 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02720355 0,09029658 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02720355 0,09017406 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02720355 0,09005187 ! toxin metabolic process GO:0009404 11 6 0,000 0,02720355 0,08993002 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02720355 0,08980849 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02720355 0,08968729 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02720355 0,08956642 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02720355 0,08944587 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02720355 0,08932565 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02720355 0,08920575 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02720355 0,08908617 ! thymic T cell selection GO:0045061 16 6 0,000 0,02720355 0,08896691 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02720355 0,08884797 ! protein lipoylation GO:0009249 10 6 0,000 0,02720355 0,08872935 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02720355 0,08861104 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02720355 0,08849305 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02720355 0,08837537 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02720355 0,08825801 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02720355 0,08814096 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02720355 0,08802421 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02720355 0,08790778 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02720355 0,08779165 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02720355 0,08767583 ! hyperosmotic response GO:0006972 10 6 0,000 0,02720355 0,08756032 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02720355 0,08744511 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02720355 0,0873302 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02720355 0,08721559 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02720355 0,08710129 ! urea metabolic process GO:0019627 7 6 0,000 0,02720355 0,08698728 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02720355 0,08687357 ! neutrophil activation GO:0042119 7 6 0,000 0,02720355 0,08676016 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02720355 0,08664704 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02720355 0,08653422 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02720355 0,08642169 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02720355 0,08630946 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02720355 0,08619751 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02720355 0,08608586 ! neuron apoptosis GO:0051402 15 6 0,000 0,02720355 0,08597449 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02720355 0,08586341 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02720355 0,08575262 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02720355 0,08564212 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02720355 0,08553189 ! carnitine transport GO:0015879 10 6 0,000 0,02720355 0,08542196 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02720355 0,0853123 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02720355 0,08520293 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02720355 0,08509383 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02720355 0,08498502 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02720355 0,08487648 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02720355 0,08476822 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02720355 0,08466023 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02720355 0,08455252 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02720355 0,08444508 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02720355 0,08433792 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02720355 0,08423103 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02720355 0,08412441 ! response to UV-C GO:0010225 14 6 0,000 0,02720355 0,08401806 ! astrocyte development GO:0014002 16 6 0,000 0,02720355 0,08391197 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02720355 0,08380616 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02720355 0,08370061 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02720355 0,08359532 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02720355 0,0834903 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02720355 0,08338555 ! response to copper ion GO:0046688 10 6 0,000 0,02720355 0,08328105 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02720355 0,08317682 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02720355 0,08307285 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02720355 0,08296914 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02720355 0,08286569 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02720355 0,08276249 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02720355 0,08265955 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02720355 0,08255687 ! hair follicle maturation GO:0048820 8 6 0,000 0,02720355 0,08245444 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02720355 0,08235227 ! Schwann cell development GO:0014044 15 6 0,000 0,02720355 0,08225035 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02720355 0,08214868 ! response to pheromone GO:0019236 6 6 0,000 0,02720355 0,08204726 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02720355 0,08194609 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02720355 0,08184517 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02720355 0,0817445 ! subpallium development GO:0021544 15 6 0,000 0,02720355 0,08164408 ! neural tube patterning GO:0021532 8 6 0,000 0,02720355 0,0815439 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02720355 0,08144397 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02720355 0,08134429 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02720355 0,08124484 ! G2 phase GO:0051319 16 6 0,000 0,02720355 0,08114564 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02720355 0,08104669 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02720355 0,08094797 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02720355 0,08084949 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02720355 0,08075125 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02720355 0,08065325 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02720355 0,08055549 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02720355 0,08045797 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02720355 0,08036068 ! receptor internalization GO:0031623 11 6 0,000 0,02720355 0,08026363 ! plasminogen activation GO:0031639 9 6 0,000 0,02720355 0,08016681 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02720355 0,08007022 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02720355 0,07997386 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 16 6 0,000 0,02720355 0,07987774 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02720355 0,07978185 ! protein destabilization GO:0031648 9 6 0,000 0,02720355 0,07968619 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02720355 0,07959076 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02720355 0,07949555 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02720355 0,07940058 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02720355 0,07930583 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02720355 0,0792113 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02720355 0,079117 ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02720355 0,07902293 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02720355 0,07892908 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02720355 0,07883545 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02720355 0,07874204 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02720355 0,07864885 ! neural plate development GO:0001840 9 6 0,000 0,02720355 0,07855589 ! catecholamine transport GO:0051937 9 6 0,000 0,02720355 0,07846314 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02720355 0,07837062 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02720355 0,07827831 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02720355 0,07818621 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02720355 0,07809434 ! maternal placenta development GO:0001893 12 6 0,000 0,02720355 0,07800268 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02720355 0,07791123 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02720355 0,07782 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02720355 0,07772898 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02720355 0,07763818 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02720355 0,07754759 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02720355 0,0774572 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02720355 0,07736703 GO:0055081|anion homeostasis, ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02738136 0,07778217 ! regulation of DNA replication GO:0006275 105 56 1,000 0,02738136 0,07769183 ! positive regulation of caspase activity GO:0043280 108 57 1,000 0,02829304 0,08018549 GO:0010952|positive regulation of peptidase activity, ! regulation of actin filament length GO:0030832 118 58 1,000 0,02921678 0,08270754 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,02921678 0,08261181 ! maintenance of location GO:0051235 124 58 1,000 0,02921678 0,08251631 ! nuclear export GO:0051168 110 59 1,000 0,03015247 0,08506061 ! lipid modification GO:0030258 112 60 1,000 0,03109998 0,08763234 ! regulation of endocytosis GO:0030100 104 60 1,000 0,03109998 0,08753138 ! adult behavior GO:0030534 104 60 1,000 0,03109998 0,08743065 ! tRNA transcription GO:0009304 17 7 0,000 0,03166542 0,08891796 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03166542 0,08881587 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03166542 0,08871402 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03166542 0,0886124 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03166542 0,08851101 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03166542 0,08840985 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03166542 0,08830893 ! sleep GO:0030431 16 7 0,000 0,03166542 0,08820824 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03166542 0,08810777 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03166542 0,08800753 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03166542 0,08790753 ! prostate gland development GO:0030850 14 7 0,000 0,03166542 0,08780774 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03166542 0,08770819 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03166542 0,08760886 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03166542 0,08750975 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03166542 0,08741087 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03166542 0,08731221 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03166542 0,08721378 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03166542 0,08711557 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03166542 0,08701757 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03166542 0,0869198 ! glycolipid transport GO:0046836 11 7 0,000 0,03166542 0,08682225 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03166542 0,08672491 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03166542 0,0866278 ! neuron adhesion GO:0007158 14 7 0,000 0,03166542 0,0865309 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03166542 0,08643421 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03166542 0,08633775 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03166542 0,0862415 ! pericardium development GO:0060039 16 7 0,000 0,03166542 0,08614546 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03166542 0,08604964 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03166542 0,08595402 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03166542 0,08585863 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03166542 0,08576344 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03166542 0,08566846 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03166542 0,0855737 ! lipoprotein transport GO:0042953 14 7 0,000 0,03166542 0,08547914 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03166542 0,08538479 ! rhythmic behavior GO:0007622 17 7 0,000 0,03166542 0,08529065 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03166542 0,08519672 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03166542 0,08510299 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03166542 0,08500948 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03166542 0,08491616 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03166542 0,08482305 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03166542 0,08473014 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03166542 0,08463744 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03166542 0,08454494 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03166542 0,08445264 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03166542 0,08436055 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03166542 0,08426865 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03166542 0,08417696 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03166542 0,08408546 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03166542 0,08399416 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03166542 0,08390306 ! spinal cord patterning GO:0021511 14 7 0,000 0,03166542 0,08381216 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03166542 0,08372145 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03166542 0,08363094 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03166542 0,08354063 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03166542 0,08345051 ! adrenal gland development GO:0030325 17 7 0,000 0,03166542 0,08336058 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03166542 0,08327085 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03166542 0,08318131 ! ovulation GO:0030728 10 7 0,000 0,03166542 0,08309197 ! adenohypophysis development GO:0021984 11 7 0,000 0,03166542 0,08300281 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03166542 0,08291385 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03166542 0,08282508 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03166542 0,08273649 ! microtubule nucleation GO:0007020 21 7 0,000 0,03166542 0,0826481 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03166542 0,0825599 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03166542 0,08247188 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03166542 0,08238405 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03166542 0,08229641 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03166542 0,08220895 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03166542 0,08212168 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03166542 0,08203459 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03166542 0,08194769 ! galactose metabolic process GO:0006012 13 7 0,000 0,03166542 0,08186098 ! vesicle fusion GO:0006906 20 7 0,000 0,03166542 0,08177444 ! response to dietary excess GO:0002021 8 7 0,000 0,03166542 0,08168809 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03166542 0,08160192 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03166542 0,08151593 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03166542 0,08143013 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03166542 0,0813445 ! organ growth GO:0035265 15 7 0,000 0,03166542 0,08125906 ! nucleoside transport GO:0015858 11 7 0,000 0,03166542 0,08117379 ! nucleoside salvage GO:0043174 11 7 0,000 0,03166542 0,0810887 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03166542 0,08100379 ! male sex determination GO:0030238 15 7 0,000 0,03166542 0,08091906 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03166542 0,08083451 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03166542 0,08075013 ! parturition GO:0007567 16 7 0,000 0,03166542 0,08066593 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03166542 0,0805819 ! rRNA modification GO:0000154 14 7 0,000 0,03166542 0,08049805 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03166542 0,08041437 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03166542 0,08033086 ! monocyte differentiation GO:0030224 16 7 0,000 0,03166542 0,08024753 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03166542 0,08016438 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03166542 0,08008139 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03166542 0,07999858 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03166542 0,07991593 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03166542 0,07983346 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03166542 0,07975116 ! fibrinolysis GO:0042730 11 7 0,000 0,03166542 0,07966902 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03166542 0,07958706 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03166542 0,07950526 ! eating behavior GO:0042755 8 7 0,000 0,03166542 0,07942364 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03166542 0,07934218 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03166542 0,07926088 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03166542 0,07917976 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03166542 0,0790988 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03166542 0,079018 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03166542 0,07893737 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03166542 0,0788569 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03166542 0,0787766 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03166542 0,07869646 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03166542 0,07861649 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03166542 0,07853667 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03166542 0,07845702 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03166542 0,07837753 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03166542 0,0782982 ! histone ubiquitination GO:0016574 9 7 0,000 0,03166542 0,07821903 ! regulation of meiosis GO:0040020 12 7 0,000 0,03166542 0,07814002 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 0,000 0,03166542 0,07806117 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03166542 0,07798248 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03166542 0,07790395 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03166542 0,07782558 ! transcription termination GO:0006353 14 7 0,000 0,03166542 0,07774736 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03166542 0,0776693 ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03166542 0,0775914 ! axonal fasciculation GO:0007413 19 7 0,000 0,03166542 0,07751365 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03166542 0,07743606 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03166542 0,07735862 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03166542 0,07728134 ! diuresis GO:0030146 12 7 0,000 0,03166542 0,07720421 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03166542 0,07712724 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03166542 0,07705042 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03166542 0,07697375 ! antibiotic transport GO:0042891 9 7 0,000 0,03166542 0,07689724 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03166542 0,07682088 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03166542 0,07674466 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03166542 0,0766686 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03166542 0,0765927 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03166542 0,07651694 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03166542 0,07644133 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03166542 0,07636587 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03166542 0,07629055 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03166542 0,07621539 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03166542 0,07614038 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03166542 0,07606551 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03166542 0,07599079 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03166542 0,07591621 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03166542 0,07584179 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03166542 0,0757675 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03166542 0,07569337 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03166542 0,07561938 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03166542 0,07554553 ! muscle adaptation GO:0043500 13 7 0,000 0,03166542 0,07547183 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03166542 0,07539827 ! retina homeostasis GO:0001895 12 7 0,000 0,03166542 0,07532485 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03166542 0,07525158 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03166542 0,07517845 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03166542 0,07510546 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03166542 0,07503261 ! positive regulation of secretion GO:0051047 110 61 1,000 0,03205916 0,075892 ! regulation of cellular component size GO:0032535 125 61 1,000 0,03205916 0,07581853 ! regulation of heart contraction GO:0008016 123 61 1,000 0,03205916 0,0757452 ! camera-type eye development GO:0043010 126 61 1,000 0,03205916 0,07567202 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,03205916 0,07559898 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,03302992 0,077813 ! tRNA processing GO:0008033 102 62 1,000 0,03302992 0,07773804 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,0340121 0,07997264 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,03500561 0,08222951 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,0360103 0,08450831 GO:0048609|reproductive process in a multicellular organism, ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03610695 0,08465381 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03610695 0,08457265 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03610695 0,08449164 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03610695 0,08441079 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03610695 0,08433009 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03610695 0,08424954 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03610695 0,08416915 ! male meiosis GO:0007140 9 8 0,000 0,03610695 0,08408892 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03610695 0,08400883 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03610695 0,0839289 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03610695 0,08384912 ! meiotic prophase I GO:0007128 14 8 0,000 0,03610695 0,08376949 ! response to zinc ion GO:0010043 12 8 0,000 0,03610695 0,08369001 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03610695 0,08361068 ! oligopeptide transport GO:0006857 16 8 0,000 0,03610695 0,08353151 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03610695 0,08345248 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03610695 0,0833736 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03610695 0,08329487 ! signal peptide processing GO:0006465 12 8 0,000 0,03610695 0,08321629 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03610695 0,08313786 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03610695 0,08305958 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03610695 0,08298144 ! succinate metabolic process GO:0006105 17 8 0,000 0,03610695 0,08290345 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03610695 0,08282561 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03610695 0,08274791 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03610695 0,08267036 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03610695 0,08259295 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03610695 0,08251569 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03610695 0,08243857 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03610695 0,0823616 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03610695 0,08228477 ! reflex GO:0060004 17 8 0,000 0,03610695 0,08220808 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03610695 0,08213154 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03610695 0,08205514 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03610695 0,08197888 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03610695 0,08190276 ! pigment granule organization GO:0048753 17 8 0,000 0,03610695 0,08182678 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03610695 0,08175095 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03610695 0,08167525 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03610695 0,0815997 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03610695 0,08152428 ! histidine catabolic process GO:0006548 10 8 0,000 0,03610695 0,081449 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03610695 0,08137387 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03610695 0,08129887 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03610695 0,08122401 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,03610695 0,08114928 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03610695 0,0810747 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03610695 0,08100025 ! melanin metabolic process GO:0006582 17 8 0,000 0,03610695 0,08092594 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03610695 0,08085176 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03610695 0,08077772 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03610695 0,08070382 ! macrophage activation GO:0042116 13 8 0,000 0,03610695 0,08063005 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03610695 0,08055641 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03610695 0,08048291 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03610695 0,08040955 ! purine salvage GO:0043101 12 8 0,000 0,03610695 0,08033631 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03610695 0,08026321 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03610695 0,08019025 ! osteoblast development GO:0002076 17 8 0,000 0,03610695 0,08011741 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03610695 0,08004471 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03610695 0,07997214 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03610695 0,0798997 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03610695 0,0798274 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03610695 0,07975522 ! response to UV-B GO:0010224 17 8 0,000 0,03610695 0,07968317 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03610695 0,07961126 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03610695 0,07953947 ! intermediate filament organization GO:0045109 12 8 0,000 0,03610695 0,07946781 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03610695 0,07939628 ! cellular extravasation GO:0045123 13 8 0,000 0,03610695 0,07932489 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03610695 0,07925361 ! response to antibiotic GO:0046677 11 8 0,000 0,03610695 0,07918247 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03610695 0,07911145 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03610695 0,07904057 ! DNA topological change GO:0006265 12 8 0,000 0,03610695 0,0789698 ! response to tropane GO:0014073 15 8 0,000 0,03610695 0,07889917 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,03610695 0,07882866 ! melanosome transport GO:0032402 13 8 0,000 0,03610695 0,07875828 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03610695 0,07868802 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03610695 0,07861789 ! mast cell activation GO:0045576 14 8 0,000 0,03610695 0,07854788 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03610695 0,078478 ! gas homeostasis GO:0033483 14 8 0,000 0,03610695 0,07840824 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03610695 0,07833861 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03610695 0,0782691 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03610695 0,07819971 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03610695 0,07813044 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03610695 0,0780613 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03610695 0,07799228 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03610695 0,07792339 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03610695 0,07785461 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03610695 0,07778595 ! response to tumor cell GO:0002347 16 8 0,000 0,03610695 0,07771742 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03610695 0,07764901 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03610695 0,07758071 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03610695 0,07751254 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03610695 0,07744449 ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03610695 0,07737655 ! hormone catabolic process GO:0042447 17 8 0,000 0,03610695 0,07730874 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03610695 0,07724104 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03610695 0,07717347 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03610695 0,07710601 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03610695 0,07703867 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03610695 0,07697144 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03610695 0,07690433 ! adult feeding behavior GO:0008343 10 8 0,000 0,03610695 0,07683735 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03610695 0,07677047 ! ATP catabolic process GO:0006200 11 8 0,000 0,03610695 0,07670371 ! blastocyst growth GO:0001832 19 8 0,000 0,03610695 0,07663707 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03610695 0,07657055 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03610695 0,07650414 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03610695 0,07643784 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03610695 0,07637166 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03610695 0,0763056 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03610695 0,07623965 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03610695 0,07617381 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03610695 0,07610809 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03610695 0,07604248 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03610695 0,07597698 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03610695 0,07591159 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03610695 0,07584632 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03610695 0,07578116 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03610695 0,07571611 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03610695 0,07565118 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03610695 0,07558635 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03610695 0,07552164 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03610695 0,07545703 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03610695 0,07539254 ! gonad development GO:0008406 115 66 1,000 0,03702606 0,07724565 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,03805276 0,07931988 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,03805276 0,07925226 GO:0035113|embryonic appendage morphogenesis, ! secondary metabolic process GO:0019748 125 67 1,000 0,03805276 0,07918475 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,03909029 0,08127454 ! extracellular matrix organization GO:0030198 146 68 1,000 0,03909029 0,08120543 ! negative regulation of cell size GO:0045792 144 69 1,000 0,04013853 0,08331218 ! cellular hormone metabolic process GO:0034754 120 69 1,000 0,04013853 0,08324146 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,04013853 0,08317085 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,04013853 0,08310037 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,04013853 0,08303001 ! axon extension GO:0048675 16 9 0,000 0,04052823 0,08376519 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04052823 0,08369438 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04052823 0,0836237 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04052823 0,08355313 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04052823 0,08348268 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04052823 0,08341235 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04052823 0,08334214 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04052823 0,08327204 ! reproductive behavior GO:0019098 22 9 0,000 0,04052823 0,08320206 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04052823 0,08313221 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04052823 0,08306246 ! UTP metabolic process GO:0046051 10 9 0,000 0,04052823 0,08299284 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04052823 0,08292333 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04052823 0,08285394 ! artery development GO:0060840 25 9 0,000 0,04052823 0,08278466 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04052823 0,0827155 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04052823 0,08264646 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04052823 0,08257753 ! equilibrioception GO:0050957 20 9 0,000 0,04052823 0,08250871 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04052823 0,08244001 ! chemosensory behavior GO:0007635 21 9 0,000 0,04052823 0,08237143 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04052823 0,08230296 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04052823 0,0822346 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04052823 0,08216635 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04052823 0,08209822 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04052823 0,0820302 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04052823 0,0819623 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04052823 0,0818945 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04052823 0,08182682 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04052823 0,08175925 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04052823 0,0816918 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04052823 0,08162445 ! protein targeting to ER GO:0045047 25 9 0,000 0,04052823 0,08155721 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04052823 0,08149009 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04052823 0,08142307 ! T cell selection GO:0045058 27 9 0,000 0,04052823 0,08135617 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04052823 0,08128937 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04052823 0,08122269 ! endosome organization GO:0007032 20 9 0,000 0,04052823 0,08115611 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04052823 0,08108964 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04052823 0,08102329 ! mannose metabolic process GO:0006013 13 9 0,000 0,04052823 0,08095704 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04052823 0,0808909 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04052823 0,08082486 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04052823 0,08075894 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04052823 0,08069312 ! receptor clustering GO:0043113 20 9 0,000 0,04052823 0,08062741 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04052823 0,0805618 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04052823 0,08049631 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04052823 0,08043092 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04052823 0,08036563 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04052823 0,08030045 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04052823 0,08023538 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04052823 0,08017041 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04052823 0,08010555 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04052823 0,08004079 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04052823 0,07997614 ! response to amine stimulus GO:0014075 13 9 0,000 0,04052823 0,07991159 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04052823 0,07984714 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04052823 0,0797828 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04052823 0,07971856 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04052823 0,07965443 ! renal water homeostasis GO:0003091 15 9 0,000 0,04052823 0,0795904 ! postreplication repair GO:0006301 25 9 0,000 0,04052823 0,07952647 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04052823 0,07946265 ! icosanoid secretion GO:0032309 15 9 0,000 0,04052823 0,07939892 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04052823 0,0793353 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04052823 0,07927178 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04052823 0,07920837 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04052823 0,07914505 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04052823 0,07908183 ! sterol catabolic process GO:0016127 14 9 0,000 0,04052823 0,07901872 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04052823 0,07895571 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04052823 0,07889279 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04052823 0,07882998 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04052823 0,07876727 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04052823 0,07870466 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04052823 0,07864214 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04052823 0,07857973 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04052823 0,07851741 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04052823 0,0784552 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04052823 0,07839308 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04052823 0,07833106 ! purine base metabolic process GO:0006144 25 9 0,000 0,04052823 0,07826914 ! pigment granule transport GO:0051904 17 9 0,000 0,04052823 0,07820731 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04052823 0,07814559 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04052823 0,07808396 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04052823 0,07802242 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04052823 0,07796099 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04052823 0,07789965 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04052823 0,07783841 ! appendage morphogenesis GO:0035107 150 72 1,000 0,04334631 0,08318541 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 1,000 0,04334631 0,08312012 ! B cell activation GO:0042113 179 72 1,000 0,04334631 0,08305492 ! appendage development GO:0048736 151 73 1,000 0,04443619 0,08507651 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 156 73 1,000 0,04443619 0,08500988 ! regulation of developmental growth GO:0048638 16 10 0,000 0,04492935 0,08588607 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,04492935 0,08581892 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04492935 0,08575187 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04492935 0,08568493 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04492935 0,0856181 ! associative learning GO:0008306 21 10 0,000 0,04492935 0,08555136 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04492935 0,08548473 ! phosphate transport GO:0006817 24 10 0,000 0,04492935 0,08541821 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04492935 0,08535179 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,04492935 0,08528547 ! CTP metabolic process GO:0046036 11 10 0,000 0,04492935 0,08521925 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04492935 0,08515314 ! GTP metabolic process GO:0046039 11 10 0,000 0,04492935 0,08508713 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04492935 0,08502122 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04492935 0,08495542 ! social behavior GO:0035176 29 10 0,000 0,04492935 0,08488971 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04492935 0,08482411 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04492935 0,08475861 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04492935 0,08469321 ! androgen metabolic process GO:0008209 17 10 0,000 0,04492935 0,08462791 ! phospholipid efflux GO:0033700 19 10 0,000 0,04492935 0,08456271 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04492935 0,08449761 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04492935 0,08443262 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04492935 0,08436772 ! pathogenesis GO:0009405 17 10 0,000 0,04492935 0,08430292 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04492935 0,08423822 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04492935 0,08417362 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04492935 0,08410912 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04492935 0,08404472 ! endoderm development GO:0007492 18 10 0,000 0,04492935 0,08398041 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04492935 0,08391621 ! arginine catabolic process GO:0006527 17 10 0,000 0,04492935 0,0838521 ! proline metabolic process GO:0006560 13 10 0,000 0,04492935 0,08378809 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04492935 0,08372418 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04492935 0,08366037 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04492935 0,08359665 ! V(D)J recombination GO:0033151 34 10 0,000 0,04492935 0,08353303 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04492935 0,08346951 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04492935 0,08340608 GO:0021952|central nervous system projection neuron axonogenesis, ! B cell proliferation GO:0042100 19 10 0,000 0,04492935 0,08334275 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04492935 0,08327951 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04492935 0,08321638 ! multicellular organism growth GO:0035264 19 10 0,000 0,04492935 0,08315333 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04492935 0,08309039 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04492935 0,08302753 ! ruffle organization GO:0031529 17 10 0,000 0,04492935 0,08296478 ! epithelial cell development GO:0002064 21 10 0,000 0,04492935 0,08290211 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04492935 0,08283955 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04492935 0,08277707 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04492935 0,08271469 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04492935 0,08265241 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04492935 0,08259022 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04492935 0,08252812 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04492935 0,08246612 ! motor axon guidance GO:0008045 22 10 0,000 0,04492935 0,0824042 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04492935 0,08234239 ! protein heterooligomerization GO:0051291 17 10 0,000 0,04492935 0,08228066 ! brain morphogenesis GO:0048854 23 10 0,000 0,04492935 0,08221903 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04492935 0,08215748 ! segment specification GO:0007379 15 10 0,000 0,04492935 0,08209604 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04492935 0,08203468 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04492935 0,08197341 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04492935 0,08191224 ! response to dsRNA GO:0043331 23 10 0,000 0,04492935 0,08185116 ! DNA ligation GO:0006266 18 10 0,000 0,04492935 0,08179016 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04492935 0,08172926 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04492935 0,08166845 ! melanosome localization GO:0032400 16 10 0,000 0,04492935 0,08160773 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04492935 0,0815471 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04492935 0,08148656 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04492935 0,08142611 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04492935 0,08136575 ! induction of an organ GO:0001759 17 10 0,000 0,04492935 0,08130548 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04492935 0,0812453 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04492935 0,08118521 ! protein sumoylation GO:0016925 17 10 0,000 0,04492935 0,0811252 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04492935 0,08106529 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04492935 0,08100546 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04492935 0,08094572 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04492935 0,08088607 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04492935 0,08082651 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04492935 0,08076703 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04492935 0,08070765 ! midbrain development GO:0030901 14 10 0,000 0,04492935 0,08064835 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04492935 0,08058913 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04492935 0,08053001 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04492935 0,08047097 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04492935 0,08041201 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04492935 0,08035315 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04492935 0,08029437 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04492935 0,08023567 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,04492935 0,08017706 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,04492935 0,08011854 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04492935 0,0800601 ! blastocyst formation GO:0001825 18 10 0,000 0,04492935 0,08000175 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04492935 0,07994348 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04492935 0,0798853 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04492935 0,0798272 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04492935 0,07976919 ! response to nicotine GO:0035094 20 10 0,000 0,04492935 0,07971126 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04492935 0,07965341 ! regulation of caspase activity GO:0043281 136 74 1,000 0,0455362 0,08067073 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 1,000 0,0455362 0,08061228 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,04664622 0,08251753 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,04664622 0,08245782 ! rhythmic process GO:0048511 142 75 1,000 0,04664622 0,0823982 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,04776613 0,0843155 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,04776613 0,08425462 ! amine catabolic process GO:0009310 136 77 1,000 0,04889582 0,08618505 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,04889582 0,08612292 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,04889582 0,08606087 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,04889582 0,08599891 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04931041 0,0866657 ! respiratory burst GO:0045730 17 11 0,000 0,04931041 0,0866034 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04931041 0,08654118 ! neuron fate specification GO:0048665 18 11 0,000 0,04931041 0,08647906 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04931041 0,08641702 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04931041 0,08635507 ! thyroid gland development GO:0030878 26 11 0,000 0,04931041 0,08629321 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,04931041 0,08623144 ! synapsis GO:0007129 14 11 0,000 0,04931041 0,08616976 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04931041 0,08610817 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04931041 0,08604666 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 0,000 0,04931041 0,08598524 ! response to pain GO:0048265 27 11 0,000 0,04931041 0,08592391 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04931041 0,08586267 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04931041 0,08580151 ! bone resorption GO:0045453 16 11 0,000 0,04931041 0,08574044 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04931041 0,08567946 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04931041 0,08561857 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04931041 0,08555776 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04931041 0,08549704 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04931041 0,0854364 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04931041 0,08537585 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04931041 0,08531539 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,04931041 0,08525501 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04931041 0,08519471 ! UV protection GO:0009650 20 11 0,000 0,04931041 0,0851345 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04931041 0,08507438 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04931041 0,08501434 ! macroautophagy GO:0016236 19 11 0,000 0,04931041 0,08495439 ! temperature homeostasis GO:0001659 18 11 0,000 0,04931041 0,08489452 ! behavioral fear response GO:0001662 27 11 0,000 0,04931041 0,08483474 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04931041 0,08477503 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04931041 0,08471542 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04931041 0,08465588 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04931041 0,08459644 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04931041 0,08453707 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04931041 0,08447779 ! regulation of organ growth GO:0046620 14 11 0,000 0,04931041 0,08441859 ! pigment granule localization GO:0051875 20 11 0,000 0,04931041 0,08435947 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04931041 0,08430044 ! vasoconstriction GO:0042310 20 11 0,000 0,04931041 0,08424149 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04931041 0,08418262 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04931041 0,08412383 ! embryonic axis specification GO:0000578 19 11 0,000 0,04931041 0,08406513 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04931041 0,0840065 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04931041 0,08394796 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04931041 0,0838895 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04931041 0,08383112 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04931041 0,08377283 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04931041 0,08371461 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04931041 0,08365648 ! prophase GO:0051324 17 11 0,000 0,04931041 0,08359842 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04931041 0,08354045 ! nucleosome positioning GO:0016584 15 11 0,000 0,04931041 0,08348255 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04931041 0,08342474 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04931041 0,08336701 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04931041 0,08330935 ! apical protein localization GO:0045176 18 11 0,000 0,04931041 0,08325178 ! acid secretion GO:0046717 20 11 0,000 0,04931041 0,08319428 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04931041 0,08313687 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04931041 0,08307953 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04931041 0,08302228 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04931041 0,0829651 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04931041 0,082908 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04931041 0,08285098 ! cholesterol efflux GO:0033344 21 11 0,000 0,04931041 0,08279404 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04931041 0,08273717 ! oocyte development GO:0048599 20 11 0,000 0,04931041 0,08268039 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04931041 0,08262368 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04931041 0,08256705 ! embryonic gut development GO:0048566 19 11 0,000 0,04931041 0,0825105 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04931041 0,08245402 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04931041 0,08239762 ! activation of innate immune response GO:0002218 16 11 0,000 0,04931041 0,0823413 GO:0002758|innate immune response-activating signal transduction, ! lysogeny GO:0030069 22 11 0,000 0,04931041 0,08228506 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04931041 0,08222889 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04931041 0,0821728 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04931041 0,08211679 ! antigen processing and presentation GO:0019882 117 78 1,000 0,05003518 0,08326699 ! protein oligomerization GO:0051259 149 79 1,000 0,05118409 0,08512099 ! meiosis GO:0007126 143 81 1,000 0,05351016 0,08892879 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,05351016 0,08886833 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05367149 0,08907572 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,05367149 0,08901524 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05367149 0,08895485 ! virus-host interaction GO:0019048 30 12 0,000 0,05367149 0,08889454 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,05367149 0,08883432 ! mating GO:0007618 17 12 0,000 0,05367149 0,08877417 ! protein complex disassembly GO:0043241 28 12 0,000 0,05367149 0,08871411 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05367149 0,08865413 ! hippocampus development GO:0021766 29 12 0,000 0,05367149 0,08859422 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05367149 0,0885344 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05367149 0,08847466 ! T cell proliferation GO:0042098 32 12 0,000 0,05367149 0,08841501 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05367149 0,08835543 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05367149 0,08829593 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05367149 0,08823651 ! drug transport GO:0015893 16 12 0,000 0,05367149 0,08817717 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05367149 0,08811791 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05367149 0,08805873 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05367149 0,08799963 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05367149 0,08794061 ! focal adhesion formation GO:0048041 37 12 0,000 0,05367149 0,08788167 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05367149 0,08782281 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05367149 0,08776402 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05367149 0,08770532 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05367149 0,08764669 ! lipid digestion GO:0044241 21 12 0,000 0,05367149 0,08758814 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05367149 0,08752967 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05367149 0,08747128 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05367149 0,08741297 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05367149 0,08735473 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05367149 0,08729657 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05367149 0,08723849 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05367149 0,08718049 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05367149 0,08712256 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05367149 0,08706471 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05367149 0,08700694 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05367149 0,08694924 ! cranial nerve development GO:0021545 23 12 0,000 0,05367149 0,08689162 ! fucose catabolic process GO:0019317 25 12 0,000 0,05367149 0,08683407 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05367149 0,08677661 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05367149 0,08671921 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,05367149 0,0866619 ! T cell homeostasis GO:0043029 28 12 0,000 0,05367149 0,08660466 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05367149 0,08654749 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05367149 0,0864904 ! oocyte differentiation GO:0009994 21 12 0,000 0,05367149 0,08643339 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05367149 0,08637645 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05367149 0,08631959 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,05367149 0,0862628 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05367149 0,08620608 ! developmental induction GO:0031128 22 12 0,000 0,05367149 0,08614944 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05367149 0,08609288 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05367149 0,08603639 ! response to cold GO:0009409 17 12 0,000 0,05367149 0,08597997 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05367149 0,08592363 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05367149 0,08586736 ! localization within membrane GO:0051668 26 12 0,000 0,05367149 0,08581116 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,05468709 0,08737773 ! meiotic cell cycle GO:0051321 144 82 1,000 0,05468709 0,08732063 ! response to drug GO:0042493 149 83 1,000 0,05587314 0,08915616 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,05587314 0,08909796 GO:0045937|positive regulation of phosphate metabolic process, ! T cell activation GO:0042110 189 84 1,000 0,0570682 0,0909443 ! digestion GO:0007586 130 84 1,000 0,0570682 0,09088502 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05801269 0,09232899 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05801269 0,09226888 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05801269 0,09220885 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05801269 0,0921489 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05801269 0,09208902 ! peroxisomal transport GO:0043574 28 13 0,000 0,05801269 0,09202923 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05801269 0,0919695 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05801269 0,09190986 ! organelle fusion GO:0048284 36 13 0,000 0,05801269 0,0918503 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05801269 0,09179081 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05801269 0,0917314 ! endocrine pancreas development GO:0031018 25 13 0,000 0,05801269 0,09167206 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05801269 0,0916128 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05801269 0,09155362 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05801269 0,09149452 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05801269 0,09143549 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05801269 0,09137654 ! methionine metabolic process GO:0006555 31 13 0,000 0,05801269 0,09131766 ! plasma membrane organization GO:0007009 27 13 0,000 0,05801269 0,09125886 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05801269 0,09120013 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05801269 0,09114148 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05801269 0,09108291 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05801269 0,09102441 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,05801269 0,09096599 ! cytokine metabolic process GO:0042107 24 13 0,000 0,05801269 0,09090764 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05801269 0,09084936 ! monoamine transport GO:0015844 21 13 0,000 0,05801269 0,09079116 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,05801269 0,09073304 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,05801269 0,09067499 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05801269 0,09061701 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05801269 0,09055911 ! protein homotetramerization GO:0051289 24 13 0,000 0,05801269 0,09050128 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05801269 0,09044353 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05801269 0,09038585 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05801269 0,09032824 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05801269 0,0902707 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05801269 0,09021324 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05801269 0,09015586 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,05801269 0,09009854 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05801269 0,0900413 ! histone methylation GO:0016571 29 13 0,000 0,05801269 0,08998413 ! chromatin silencing GO:0006342 29 13 0,000 0,05801269 0,08992703 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05801269 0,08987001 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,05801269 0,08981306 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05801269 0,08975618 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05801269 0,08969937 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05801269 0,08964264 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05801269 0,08958597 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05801269 0,08952938 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05801269 0,08947286 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05801269 0,08941641 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05801269 0,08936003 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05801269 0,08930372 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05801269 0,08924749 ! insulin secretion GO:0030073 24 13 0,000 0,05801269 0,08919132 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05801269 0,08913522 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05801269 0,0890792 ! acrosome reaction GO:0007340 19 13 0,000 0,05801269 0,08902325 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05801269 0,08896736 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05801269 0,08891155 ! negative regulation of growth GO:0045926 168 85 1,000 0,05827217 0,08925324 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,05827217 0,08919732 ! regulation of protein transport GO:0051223 165 87 1,000 0,06070641 0,09286523 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 1,000 0,06193648 0,09468762 ! rRNA transcription GO:0009303 28 14 0,000 0,0623341 0,0952359 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,0623341 0,09517638 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,0623341 0,09511693 ! water transport GO:0006833 21 14 0,000 0,0623341 0,09505756 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,0623341 0,09499826 ! non-recombinational repair GO:0000726 29 14 0,000 0,0623341 0,09493903 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,0623341 0,09487988 ! RNA polyadenylation GO:0043631 32 14 0,000 0,0623341 0,0948208 ! lipid localization GO:0010876 32 14 0,000 0,0623341 0,0947618 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,0623341 0,09470286 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,0623341 0,09464401 ! regulated secretory pathway GO:0045055 24 14 0,000 0,0623341 0,09458522 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,0623341 0,09452651 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,0623341 0,09446787 ! arginine metabolic process GO:0006525 21 14 0,000 0,0623341 0,0944093 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,0623341 0,09435081 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,0623341 0,09429239 ! regulation of heart rate GO:0002027 25 14 0,000 0,0623341 0,09423404 ! fear response GO:0042596 34 14 0,000 0,0623341 0,09417576 ! organic alcohol transport GO:0015850 29 14 0,000 0,0623341 0,09411756 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,0623341 0,09405942 ! embryo implantation GO:0007566 30 14 0,000 0,0623341 0,09400136 ! neutral amino acid transport GO:0015804 28 14 0,000 0,0623341 0,09394337 ! bone mineralization GO:0030282 18 14 0,000 0,0623341 0,09388545 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,0623341 0,09382761 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,0623341 0,09376983 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,0623341 0,09371213 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,0623341 0,09365449 ! regulation of cellular pH GO:0030641 27 14 0,000 0,0623341 0,09359693 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,0623341 0,09353944 ! ribosome assembly GO:0042255 18 14 0,000 0,0623341 0,09348202 ! cerebellum development GO:0021549 23 14 0,000 0,0623341 0,09342467 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,0623341 0,09336739 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,0623341 0,09331017 ! response to gamma radiation GO:0010332 30 14 0,000 0,0623341 0,09325303 ! NADP metabolic process GO:0006739 24 14 0,000 0,0623341 0,09319596 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,0623341 0,09313896 ! oxygen transport GO:0015671 22 14 0,000 0,0623341 0,09308203 ! male genitalia development GO:0030539 26 14 0,000 0,0623341 0,09302517 ! regulation of axon extension GO:0030516 43 14 0,000 0,0623341 0,09296838 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,0623341 0,09291166 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,0623341 0,092855 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,0623341 0,09279842 ! regulation of DNA binding GO:0051101 167 89 1,000 0,06317503 0,09399305 ! regulation of neurological system process GO:0031644 175 89 1,000 0,06317503 0,09393584 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,06442196 0,09573166 ! gland development GO:0048732 220 91 1,000 0,06567718 0,0975376 ! defense response to bacterium GO:0042742 112 91 1,000 0,06567718 0,09747835 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0666358 0,09884109 ! lactation GO:0007595 30 15 0,000 0,0666358 0,09878111 ! reproductive cellular process GO:0048610 22 15 0,000 0,0666358 0,09872121 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0666358 0,09866137 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,0666358 0,09860162 ! superoxide anion generation GO:0042554 22 15 0,000 0,0666358 0,09854193 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,0666358 0,09848232 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,0666358 0,09842277 ! copper ion transport GO:0006825 22 15 0,000 0,0666358 0,0983633 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,0666358 0,09830391 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,0666358 0,09824458 ! sulfate transport GO:0008272 27 15 0,000 0,0666358 0,09818532 ! response to cAMP GO:0051591 25 15 0,000 0,0666358 0,09812614 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,0666358 0,09806703 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,0666358 0,09800799 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,0666358 0,09794902 ! response to hexose stimulus GO:0009746 25 15 0,000 0,0666358 0,09789012 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,0666358 0,09783129 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,0666358 0,09777253 ! vesicle coating GO:0006901 38 15 0,000 0,0666358 0,09771385 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,0666358 0,09765523 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,0666358 0,09759668 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,0666358 0,09753821 ! regulation of exocytosis GO:0017157 26 15 0,000 0,0666358 0,0974798 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,0666358 0,09742146 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,0666358 0,0973632 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,0666358 0,097305 ! regulation of vasodilation GO:0042312 27 15 0,000 0,0666358 0,09724687 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,0666358 0,09718882 ! histone deacetylation GO:0016575 24 15 0,000 0,0666358 0,09713083 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0666358 0,09707291 ! water homeostasis GO:0030104 28 15 0,000 0,0666358 0,09701506 ! cofactor transport GO:0051181 30 15 0,000 0,0666358 0,09695728 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0666358 0,09689956 ! muscle maintenance GO:0046716 26 15 0,000 0,0666358 0,09684192 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,0666358 0,09678434 ! intestinal absorption GO:0050892 31 15 0,000 0,0666358 0,09672684 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,0666358 0,0966694 ! heme biosynthetic process GO:0006783 33 15 0,000 0,0666358 0,09661203 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,0666358 0,09655473 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,0666358 0,09649749 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,0666358 0,09644032 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,0666358 0,09638323 ! actin filament polymerization GO:0030041 27 15 0,000 0,0666358 0,09632619 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,0666358 0,09626923 ! vitamin metabolic process GO:0006766 153 93 1,000 0,06821207 0,09848824 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,06949154 0,10027634 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,06949154 0,10021714 ! ATP biosynthetic process GO:0006754 197 95 1,000 0,0707789 0,10201348 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,07091789 0,10215355 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07091789 0,10209335 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07091789 0,10203322 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07091789 0,10197317 ! bone remodeling GO:0046849 28 16 0,000 0,07091789 0,10191318 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,07091789 0,10185327 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07091789 0,10179343 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07091789 0,10173365 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07091789 0,10167395 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07091789 0,10161432 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07091789 0,10155476 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07091789 0,10149526 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07091789 0,10143584 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07091789 0,10137649 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07091789 0,1013172 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07091789 0,10125799 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07091789 0,10119884 ! pituitary gland development GO:0021983 30 16 0,000 0,07091789 0,10113976 ! response to osmotic stress GO:0006970 27 16 0,000 0,07091789 0,10108075 ! lysosomal transport GO:0007041 31 16 0,000 0,07091789 0,10102182 ! fructose metabolic process GO:0006000 25 16 0,000 0,07091789 0,10096294 ! L-amino acid transport GO:0015807 33 16 0,000 0,07091789 0,10090414 ! stem cell development GO:0048864 46 16 0,000 0,07091789 0,10084541 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07091789 0,10078674 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07091789 0,10072815 ! axon cargo transport GO:0008088 46 16 0,000 0,07091789 0,10066962 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07091789 0,10061116 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,07091789 0,10055276 ! DNA replication initiation GO:0006270 28 16 0,000 0,07091789 0,10049444 ! neuron recognition GO:0008038 40 16 0,000 0,07091789 0,10043618 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07091789 0,10037799 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07091789 0,10031987 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07091789 0,10026181 ! biomineral formation GO:0031214 22 16 0,000 0,07091789 0,10020382 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07091789 0,1001459 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07091789 0,10008805 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07091789 0,10003026 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07091789 0,09997254 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07091789 0,09991489 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07091789 0,0998573 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07091789 0,09979978 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,07091789 0,09974232 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,07091789 0,09968493 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,07337687 0,10308205 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,07337687 0,10302281 ! regulation of protein localization GO:0032880 188 97 1,000 0,07337687 0,10296364 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,07518046 0,1054339 ! metencephalon development GO:0022037 32 17 0,000 0,07518046 0,10537341 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,07518046 0,10531299 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,07518046 0,10525264 ! signal complex assembly GO:0007172 47 17 0,000 0,07518046 0,10519236 ! endothelial cell migration GO:0043542 31 17 0,000 0,07518046 0,10513215 ! gene silencing by RNA GO:0031047 38 17 0,000 0,07518046 0,105072 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,07518046 0,10501193 ! glial cell development GO:0021782 28 17 0,000 0,07518046 0,10495192 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,07518046 0,10489198 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,07518046 0,10483211 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,07518046 0,10477231 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,07518046 0,10471258 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,07518046 0,10465291 ! myoblast differentiation GO:0045445 50 17 0,000 0,07518046 0,10459331 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,07518046 0,10453378 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,07518046 0,10447432 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,07518046 0,10441493 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,07518046 0,1043556 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,07518046 0,10429634 ! membrane budding GO:0006900 42 17 0,000 0,07518046 0,10423715 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,07518046 0,10417802 ! regulation of protein binding GO:0043393 33 17 0,000 0,07518046 0,10411897 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,07518046 0,10405998 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,07518046 0,10400105 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,07518046 0,10394219 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,07518046 0,1038834 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,07518046 0,10382468 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,07518046 0,10376602 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,07518046 0,10370743 ! steroid catabolic process GO:0006706 34 17 0,000 0,07518046 0,1036489 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,07518046 0,10359044 ! gas transport GO:0015669 26 17 0,000 0,07518046 0,10353205 ! organic cation transport GO:0015695 32 17 0,000 0,07518046 0,10347372 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,07518046 0,10341546 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,07518046 0,10335726 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,07733053 0,10625336 GO:0060538|skeletal muscle organ development, ! hormone metabolic process GO:0042445 171 100 1,000 0,07733053 0,10619364 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07942358 0,10900664 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07942358 0,10894543 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07942358 0,1088843 ! limbic system development GO:0021761 40 18 0,000 0,07942358 0,10882323 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07942358 0,10876223 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07942358 0,1087013 ! adult walking behavior GO:0007628 36 18 0,000 0,07942358 0,10864044 ! heart looping GO:0001947 34 18 0,000 0,07942358 0,10857964 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07942358 0,10851891 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,07942358 0,10845825 ! centrosome cycle GO:0007098 26 18 0,000 0,07942358 0,10839766 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07942358 0,10833714 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07942358 0,10827668 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07942358 0,1082163 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,07942358 0,10815597 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 0,000 0,07942358 0,10809572 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07942358 0,10803553 ! DNA integration GO:0015074 32 18 0,000 0,07942358 0,10797541 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07942358 0,10791536 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07942358 0,10785537 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07942358 0,10779545 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07942358 0,1077356 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07942358 0,10767581 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,07942358 0,10761609 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07942358 0,10755644 ! nerve development GO:0021675 34 18 0,000 0,07942358 0,10749685 ! defense response to virus GO:0051607 43 18 0,000 0,07942358 0,10743733 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07942358 0,10737787 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,07942358 0,10731848 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08364736 0,11296324 ! positive regulation of translation GO:0045727 31 19 0,000 0,08364736 0,11290083 ! negative regulation of defense response GO:0031348 27 19 0,000 0,08364736 0,11283849 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,08364736 0,11277622 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,08364736 0,11271401 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08364736 0,11265188 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,08364736 0,11258981 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,08364736 0,11252781 ! inositol metabolic process GO:0006020 33 19 0,000 0,08364736 0,11246588 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08364736 0,11240402 ! memory GO:0007613 34 19 0,000 0,08364736 0,11234223 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,08364736 0,1122805 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08364736 0,11221884 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08364736 0,11215725 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,08364736 0,11209573 ! cerebral cortex development GO:0021987 40 19 0,000 0,08364736 0,11203427 ! pigmentation during development GO:0048066 42 19 0,000 0,08364736 0,11197288 ! heme metabolic process GO:0042168 40 19 0,000 0,08364736 0,11191156 ! neuromuscular junction development GO:0007528 43 19 0,000 0,08364736 0,11185031 ! protein export from nucleus GO:0006611 40 19 0,000 0,08364736 0,11178912 ! heart process GO:0003015 32 19 0,000 0,08364736 0,111728 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,08364736 0,11166694 ! visual learning GO:0008542 38 19 0,000 0,08364736 0,11160596 ! cellular pigmentation GO:0033059 37 19 0,000 0,08364736 0,11154504 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,08364736 0,11148418 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08364736 0,1114234 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,08364736 0,11136267 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08364736 0,11130202 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,08364736 0,11124143 ! cilium assembly GO:0042384 38 19 0,000 0,08364736 0,11118091 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08364736 0,11112045 ! protein secretion GO:0009306 45 20 0,000 0,08785188 0,11664247 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08785188 0,11657911 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08785188 0,11651582 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,08785188 0,1164526 ! skin development GO:0043588 42 20 0,000 0,08785188 0,11638945 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08785188 0,11632637 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,08785188 0,11626335 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,08785188 0,1162004 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08785188 0,11613752 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,08785188 0,11607471 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,08785188 0,11601197 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08785188 0,11594929 ! response to alkaloid GO:0043279 38 20 0,000 0,08785188 0,11588669 ! pancreas development GO:0031016 40 20 0,000 0,08785188 0,11582415 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,08785188 0,11576167 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08785188 0,11569927 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08785188 0,11563693 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,08785188 0,11557466 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 0,000 0,08785188 0,11551246 ! actin filament bundle formation GO:0051017 47 20 0,000 0,08785188 0,11545032 ! body fluid secretion GO:0007589 33 20 0,000 0,08785188 0,11538825 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08785188 0,11532625 ! peptide secretion GO:0002790 38 20 0,000 0,08785188 0,11526431 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08785188 0,11520244 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08785188 0,11514064 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,08785188 0,1150789 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08785188 0,11501723 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08785188 0,11495562 ! cell-cell junction organization GO:0045216 43 20 0,000 0,08785188 0,11489408 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,08785188 0,11483261 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08785188 0,1147712 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08785188 0,11470986 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08785188 0,11464858 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08785188 0,11458737 ! regulation of glucose import GO:0046324 30 20 0,000 0,08785188 0,11452622 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,08785188 0,11446514 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,08785188 0,11440413 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08785188 0,11434318 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,08785188 0,11428229 ! regulation of cell killing GO:0031341 46 21 0,000 0,09203722 0,11966309 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,09203722 0,11959944 ! hormone secretion GO:0046879 39 21 0,000 0,09203722 0,11953585 ! cAMP metabolic process GO:0046058 41 21 0,000 0,09203722 0,11947234 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,09203722 0,11940889 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,09203722 0,11934551 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,09203722 0,1192822 ! smooth muscle contraction GO:0006939 48 21 0,000 0,09203722 0,11921895 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 0,000 0,09203722 0,11915577 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,09203722 0,11909266 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,09203722 0,11902961 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,09203722 0,11896663 ! plasma membrane fusion GO:0045026 33 21 0,000 0,09203722 0,11890372 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,09203722 0,11884088 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,09203722 0,1187781 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,09203722 0,11871538 ! sensory perception of pain GO:0019233 33 21 0,000 0,09203722 0,11865274 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,09203722 0,11859016 ! diencephalon development GO:0021536 36 21 0,000 0,09203722 0,11852764 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,09203722 0,11846519 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,09203722 0,11840281 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,09203722 0,11834049 ! collagen catabolic process GO:0030574 29 21 0,000 0,09203722 0,11827824 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,09203722 0,11821606 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,09203722 0,11815394 ! actin filament-based movement GO:0030048 47 21 0,000 0,09203722 0,11809188 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,09203722 0,11802989 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,09620348 0,12330803 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09620348 0,12324337 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09620348 0,12317878 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09620348 0,12311425 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,09620348 0,12304979 ! microtubule-based transport GO:0010970 59 22 0,000 0,09620348 0,1229854 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,09620348 0,12292108 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,09620348 0,12285682 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,09620348 0,12279264 ! vacuolar transport GO:0007034 41 22 0,000 0,09620348 0,12272851 ! central nervous system neuron development GO:0021954 47 22 0,000 0,09620348 0,12266446 ! fucose metabolic process GO:0006004 44 22 0,000 0,09620348 0,12260047 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09620348 0,12253655 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09620348 0,1224727 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,09620348 0,12240891 ! cell aging GO:0007569 48 22 0,000 0,09620348 0,12234519 ! stem cell differentiation GO:0048863 57 22 0,000 0,09620348 0,12228153 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,09620348 0,12221794 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,09620348 0,12215442 ! cytolysis GO:0019835 27 22 0,000 0,09620348 0,12209096 ! renal system process GO:0003014 42 22 0,000 0,09620348 0,12202757 ! vasodilation GO:0042311 40 22 0,000 0,09620348 0,12196425 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09620348 0,12190099 ! G1 phase GO:0051318 44 22 0,000 0,09620348 0,12183779 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09620348 0,12177467 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,09620348 0,1217116 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,09620348 0,1216486 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,09620348 0,12158567 ! peptidyl-serine modification GO:0018209 50 22 0,000 0,09620348 0,1215228 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09620348 0,12146 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09620348 0,12139726 ! sarcomere organization GO:0045214 32 22 0,000 0,09620348 0,12133459 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,09620348 0,12127198 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09620348 0,12120944 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,09620348 0,12114696 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,09620348 0,12108455 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09620348 0,1210222 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,09620348 0,12095991 ! protein stabilization GO:0050821 41 22 0,000 0,09620348 0,12089769 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,10035074 0,12604465 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,10035074 0,12597988 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,10035074 0,12591518 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10035074 0,12585054 ! glycerol metabolic process GO:0006071 40 23 0,000 0,10035074 0,12578597 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10035074 0,12572146 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10035074 0,12565702 ! axis specification GO:0009798 43 23 0,000 0,10035074 0,12559265 ! visual behavior GO:0007632 46 23 0,000 0,10035074 0,12552834 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,10035074 0,1254641 ! response to ethanol GO:0045471 47 23 0,000 0,10035074 0,12539992 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10035074 0,12533581 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,10035074 0,12527177 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10035074 0,12520779 ! peroxisome organization GO:0007031 43 23 0,000 0,10035074 0,12514387 ! lysosome organization GO:0007040 47 23 0,000 0,10035074 0,12508003 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,10035074 0,12501624 ! vesicle targeting GO:0006903 49 23 0,000 0,10035074 0,12495252 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,10035074 0,12488887 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10035074 0,12482528 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10035074 0,12476176 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10035074 0,1246983 ! DNA modification GO:0006304 36 23 0,000 0,10035074 0,1246349 ! fatty acid transport GO:0015908 47 23 0,000 0,10035074 0,12457157 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,10035074 0,1245083 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,10035074 0,1244451 ! hormone transport GO:0009914 41 23 0,000 0,10035074 0,12438196 ! cell-cell recognition GO:0009988 28 23 0,000 0,10035074 0,12431889 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10035074 0,12425588 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,10447908 0,12930212 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,10447908 0,12923665 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,10447908 0,12917125 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,10447908 0,12910591 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10447908 0,12904064 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10447908 0,12897544 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10447908 0,1289103 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,10447908 0,12884522 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,10447908 0,12878022 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,10447908 0,12871527 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,10447908 0,1286504 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10447908 0,12858559 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,10447908 0,12852084 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,10447908 0,12845616 ! sex determination GO:0007530 48 24 0,000 0,10447908 0,12839154 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10447908 0,12832699 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,10447908 0,12826251 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,10447908 0,12819809 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,10447908 0,12813373 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10447908 0,12806944 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,10447908 0,12800521 ! membrane depolarization GO:0051899 45 24 0,000 0,10447908 0,12794105 ! pallium development GO:0021543 56 24 0,000 0,10447908 0,12787695 ! oogenesis GO:0048477 44 24 0,000 0,10447908 0,12781291 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,10447908 0,12774894 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,10447908 0,12768504 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,10447908 0,12762119 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10447908 0,12755742 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10447908 0,1274937 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10447908 0,12743005 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10447908 0,12736646 ! regulation of amine transport GO:0051952 41 24 0,000 0,10447908 0,12730294 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,10447908 0,12723948 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,10858859 0,13217834 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,10858859 0,13211252 ! leukocyte adhesion GO:0007159 55 25 0,000 0,10858859 0,13204675 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,10858859 0,13198106 ! phototransduction GO:0007602 37 25 0,000 0,10858859 0,13191543 ! keratinization GO:0031424 37 25 0,000 0,10858859 0,13184987 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,10858859 0,13178437 ! vacuole organization GO:0007033 49 25 0,000 0,10858859 0,13171893 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,10858859 0,13165356 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,10858859 0,13158826 ! receptor metabolic process GO:0043112 53 25 0,000 0,10858859 0,13152302 ! chromosome condensation GO:0030261 48 25 0,000 0,10858859 0,13145784 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,10858859 0,13139273 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,10858859 0,13132769 ! immunoglobulin production GO:0002377 62 25 0,000 0,10858859 0,13126271 GO:0002440|production of molecular mediator of immune response, ! leukocyte homeostasis GO:0001776 50 25 0,000 0,10858859 0,13119779 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,10858859 0,13113294 ! protein tetramerization GO:0051262 57 25 0,000 0,10858859 0,13106815 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,11267936 0,13593861 ! myelination GO:0042552 50 26 0,000 0,11267936 0,13587151 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11267936 0,13580448 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11267936 0,13573752 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,11267936 0,13567062 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,11267936 0,13560378 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11267936 0,13553702 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,11267936 0,13547032 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11267936 0,13540368 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11267936 0,13533711 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,11267936 0,13527061 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,11267936 0,13520417 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,11267936 0,13513779 ! osteoblast differentiation GO:0001649 63 26 0,000 0,11267936 0,13507148 ! response to endoplasmic reticulum stress GO:0034976 46 26 0,000 0,11267936 0,13500524 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11267936 0,13493906 ! negative regulation of cell development GO:0010721 83 26 0,000 0,11267936 0,13487295 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11267936 0,1348069 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11267936 0,13474091 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11267936 0,13467499 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,11267936 0,13460914 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,11267936 0,13454334 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,11267936 0,13447762 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11267936 0,13441195 ! blastocyst development GO:0001824 50 26 0,000 0,11267936 0,13434635 ! telomere organization GO:0032200 46 26 0,000 0,11267936 0,13428082 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11267936 0,13421535 ! alditol metabolic process GO:0019400 44 26 0,000 0,11267936 0,13414994 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,11267936 0,1340846 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11267936 0,13401932 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,11675147 0,13879506 ! embryonic pattern specification GO:0009880 49 27 0,000 0,11675147 0,13872755 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,11675147 0,13866011 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,11675147 0,13859274 ! iron ion transport GO:0006826 65 27 0,000 0,11675147 0,13852543 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,11675147 0,13845818 ! superoxide metabolic process GO:0006801 41 27 0,000 0,11675147 0,138391 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,11675147 0,13832388 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,11675147 0,13825683 ! response to toxin GO:0009636 49 27 0,000 0,11675147 0,13818985 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,11675147 0,13812293 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,11675147 0,13805607 ! leukocyte proliferation GO:0070661 59 27 0,000 0,11675147 0,13798928 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,11675147 0,13792256 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,12080501 0,14264217 ! neuron fate commitment GO:0048663 52 28 0,000 0,12080501 0,14257326 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,12080501 0,14250442 ! vesicle docking GO:0048278 55 28 0,000 0,12080501 0,14243564 ! circadian rhythm GO:0007623 56 28 0,000 0,12080501 0,14236693 ! dendrite development GO:0016358 67 28 0,000 0,12080501 0,14229829 ! fat cell differentiation GO:0045444 57 28 0,000 0,12080501 0,14222971 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,12080501 0,1421612 ! sperm motility GO:0030317 37 28 0,000 0,12080501 0,14209275 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,12080501 0,14202437 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,12080501 0,14195606 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,12080501 0,14188781 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,12080501 0,14181963 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,12080501 0,14175151 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,12080501 0,14168346 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,12080501 0,14161547 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,12080501 0,14154755 ! glutathione metabolic process GO:0006749 42 28 0,000 0,12080501 0,14147969 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,12080501 0,1414119 ! lipid oxidation GO:0034440 48 28 0,000 0,12080501 0,14134418 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,12080501 0,14127652 ! translational initiation GO:0006413 66 29 0,000 0,12484006 0,14592549 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,12484006 0,1458557 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,12484006 0,14578598 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! ER-nuclear signaling pathway GO:0006984 52 29 0,000 0,12484006 0,14571632 ! autophagy GO:0006914 47 29 0,000 0,12484006 0,14564674 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,12484006 0,14557722 ! synaptogenesis GO:0007416 46 29 0,000 0,12484006 0,14550776 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,12484006 0,14543837 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,12484006 0,14536905 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,12484006 0,14529979 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,12484006 0,1452306 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,1288567 0,14983195 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,1288567 0,14976067 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,1288567 0,14968946 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,1288567 0,14961831 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,1288567 0,14954723 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,1288567 0,14947622 ! myofibril assembly GO:0030239 50 30 0,000 0,1288567 0,14940528 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,1288567 0,1493344 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,1288567 0,1492636 ! cell fate determination GO:0001709 64 30 0,000 0,1288567 0,14919286 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,1288567 0,14912218 ! phospholipid transport GO:0015914 65 30 0,000 0,1288567 0,14905157 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,1288567 0,14898103 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,1288567 0,14891056 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,1288567 0,14884015 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,1288567 0,14876981 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 0,000 0,1288567 0,14869954 ! regulation of coagulation GO:0050818 52 30 0,000 0,1288567 0,14862933 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,13285502 0,15316886 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,13285502 0,15309661 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,13285502 0,15302443 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,13285502 0,15295232 ! cell junction assembly GO:0034329 85 31 0,000 0,13285502 0,15288027 ! regulation of innate immune response GO:0045088 57 31 0,000 0,13285502 0,1528083 ! peptide transport GO:0015833 60 31 0,000 0,13285502 0,15273639 ! male gonad development GO:0008584 56 31 0,000 0,13285502 0,15266455 ! iron ion homeostasis GO:0055072 60 31 0,000 0,13285502 0,15259277 ! detection of light stimulus GO:0009583 44 31 0,000 0,13285502 0,15252106 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,13285502 0,15244942 ! natural killer cell activation GO:0030101 50 31 0,000 0,13285502 0,15237785 ! ensheathment of neurons GO:0007272 64 31 0,000 0,13285502 0,15230635 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,13285502 0,15223491 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,13285502 0,15216354 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,13285502 0,15209223 ! response to heat GO:0009408 54 31 0,000 0,13285502 0,15202099 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,13285502 0,15194982 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,13683511 0,15642871 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,13683511 0,15635555 ! collagen metabolic process GO:0032963 49 32 0,000 0,13683511 0,15628245 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,13683511 0,15620942 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,13683511 0,15613646 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,13683511 0,15606357 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,13683511 0,15599074 ! muscle cell development GO:0055001 52 32 0,000 0,13683511 0,15591799 ! mesoderm formation GO:0001707 73 32 0,000 0,13683511 0,1558453 ! peripheral nervous system development GO:0007422 68 32 0,000 0,13683511 0,15577268 ! hindbrain development GO:0030902 65 32 0,000 0,13683511 0,15570012 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,13683511 0,15562764 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,13683511 0,15555522 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,13683511 0,15548287 ! gene silencing GO:0016458 71 32 0,000 0,13683511 0,15541058 ! regulation of pH GO:0006885 56 33 0,000 0,14079703 0,15983603 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,14079703 0,15976179 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,14079703 0,15968763 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,14079703 0,15961352 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,14079703 0,15953949 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,14079703 0,15946553 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,14079703 0,15939163 ! response to ionizing radiation GO:0010212 74 33 0,000 0,14079703 0,15931781 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,14079703 0,15924405 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,14079703 0,15917036 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,14079703 0,15909674 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,14079703 0,15902318 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,14079703 0,1589497 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,14474088 0,16332655 ! glial cell differentiation GO:0010001 67 34 0,000 0,14474088 0,16325114 ! post-embryonic development GO:0009791 76 34 0,000 0,14474088 0,16317581 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,14474088 0,16310054 ! cholesterol transport GO:0030301 62 34 0,000 0,14474088 0,16302534 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,14474088 0,16295022 ! spliceosome assembly GO:0000245 75 34 0,000 0,14474088 0,16287516 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,14474088 0,16280017 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,14474088 0,16272525 ! formation of primary germ layer GO:0001704 76 34 0,000 0,14474088 0,1626504 ! cell fate specification GO:0001708 56 34 0,000 0,14474088 0,16257562 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,14866674 0,16690848 ! negative regulation of secretion GO:0051048 68 35 0,000 0,14866674 0,16683181 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,14866674 0,16675521 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,14866674 0,16667868 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,14866674 0,16660222 ! membrane docking GO:0022406 69 35 0,000 0,14866674 0,16652583 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,14866674 0,16644952 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,14866674 0,16637327 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,14866674 0,16629709 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,14866674 0,16622098 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,14866674 0,16614494 ! ceramide metabolic process GO:0006672 72 35 0,000 0,14866674 0,16606897 ! telencephalon development GO:0021537 81 35 0,000 0,14866674 0,16599307 ! sterol transport GO:0015918 63 35 0,000 0,14866674 0,16591724 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,14866674 0,16584148 ! vesicle localization GO:0051648 70 35 0,000 0,14866674 0,16576579 ! regulation of muscle development GO:0048634 82 36 0,000 0,15257469 0,1700456 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,15257469 0,16996806 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,15257469 0,16989059 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,15257469 0,16981319 ! protein targeting to membrane GO:0006612 75 36 0,000 0,15257469 0,16973587 ! aerobic respiration GO:0009060 56 36 0,000 0,15257469 0,16965861 ! cytokine production GO:0001816 68 36 0,000 0,15257469 0,16958142 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,15257469 0,1695043 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,15646481 0,17374705 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 96 37 0,000 0,15646481 0,17366811 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,15646481 0,17358925 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,15646481 0,17351045 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,15646481 0,17343172 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,15646481 0,17335307 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,15646481 0,17327449 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,16033718 0,17748243 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,16033718 0,17740205 ! meiosis I GO:0007127 74 38 0,000 0,16033718 0,17732174 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,16033718 0,1772415 ! organic anion transport GO:0015711 82 38 0,000 0,16033718 0,17716134 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,16033718 0,17708125 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,16033718 0,17700123 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,16033718 0,17692128 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,16033718 0,17684141 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,16033718 0,17676161 ! regulation of protein stability GO:0031647 77 38 0,000 0,16033718 0,17668188 ! spermatid development GO:0007286 69 38 0,000 0,16033718 0,17660222 ! glycogen metabolic process GO:0005977 63 38 0,000 0,16033718 0,17652263 ! pigment metabolic process GO:0042440 87 38 0,000 0,16033718 0,17644312 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,16419188 0,18060367 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,16419188 0,18052239 ! negative regulation of binding GO:0051100 71 39 0,000 0,16419188 0,18044119 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,16419188 0,18036005 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,16419188 0,18027899 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,16419188 0,180198 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 0,000 0,16419188 0,18011709 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 0,000 0,16802899 0,18424364 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,16802899 0,18416098 ! learning GO:0007612 82 40 0,000 0,16802899 0,1840784 ! nucleus organization GO:0006997 73 40 0,000 0,16802899 0,18399589 ! lipid homeostasis GO:0055088 75 40 0,000 0,16802899 0,18391345 ! mismatch repair GO:0006298 58 40 0,000 0,16802899 0,18383109 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,16802899 0,1837488 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,16802899 0,18366659 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,16802899 0,18358445 ! mRNA catabolic process GO:0006402 79 41 0,000 0,1718486 0,18767372 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,1718486 0,18758987 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,1718486 0,18750608 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,1718486 0,18742238 ! feeding behavior GO:0007631 69 41 0,000 0,1718486 0,18733874 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,1718486 0,18725518 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,1718486 0,1871717 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,1718486 0,18708829 ! spermatid differentiation GO:0048515 73 41 0,000 0,1718486 0,18700495 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,17565077 0,19105736 ! ear morphogenesis GO:0042471 64 42 0,000 0,17565077 0,19097234 ! organic ether metabolic process GO:0018904 59 42 0,000 0,17565077 0,19088738 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,17565077 0,19080251 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,17565077 0,19071771 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,17565077 0,19063298 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,17565077 0,19054833 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,17565077 0,19046375 ! cytokinesis GO:0000910 84 42 0,000 0,17565077 0,19037925 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,1794356 0,1943952 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,1794356 0,19430903 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,1794356 0,19422294 ! regulation of tube size GO:0035150 76 43 0,000 0,1794356 0,19413692 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,1794356 0,19405098 ! glucose transport GO:0015758 66 43 0,000 0,1794356 0,19396512 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,1794356 0,19387933 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,1794356 0,19379362 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,1794356 0,19370799 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,1794356 0,19362243 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,1794356 0,19353694 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,1794356 0,19345153 ! ion transmembrane transport GO:0034220 79 43 0,000 0,1794356 0,1933662 ! neuron migration GO:0001764 85 43 0,000 0,1794356 0,19328094 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,1794356 0,19319576 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,18320316 0,19716533 ! energy reserve metabolic process GO:0006112 76 44 0,000 0,18320316 0,19707852 ! hexose transport GO:0008645 68 44 0,000 0,18320316 0,19699177 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,18320316 0,19690511 ! phagocytosis GO:0006909 105 44 0,000 0,18320316 0,19681852 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,18320316 0,196732 ! double-strand break repair GO:0006302 85 44 0,000 0,18320316 0,19664557 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,18695352 0,20058298 ! induction of apoptosis by intracellular signals GO:0008629 95 45 0,000 0,18695352 0,20049493 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,18695352 0,20040695 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,18695352 0,20031906 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,18695352 0,20023123 ! female gamete generation GO:0007292 71 45 0,000 0,18695352 0,20014349 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,18695352 0,20005582 ! polyol metabolic process GO:0019751 77 45 0,000 0,18695352 0,19996823 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,19068677 0,20387211 ! glycolysis GO:0006096 71 46 0,000 0,19068677 0,20378293 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,19068677 0,20369382 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,19068677 0,2036048 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,19068677 0,20351585 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,19068677 0,20342697 ! pigmentation GO:0043473 103 46 0,000 0,19068677 0,20333818 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,19440298 0,2072105 ! positive regulation of defense response GO:0031349 88 48 0,000 0,19810223 0,21106138 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,19810223 0,21096937 ! mitochondrial transport GO:0006839 94 48 0,000 0,19810223 0,21087745 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,19810223 0,2107856 ! cellular component disassembly GO:0022411 89 48 0,000 0,19810223 0,21069384 ! endosome transport GO:0016197 127 48 0,000 0,19810223 0,21060215 ! male sex differentiation GO:0046661 93 48 0,000 0,19810223 0,21051055 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,19810223 0,21041902 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,19810223 0,21032757 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,19810223 0,21023621 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,19810223 0,21014492 ! methylation GO:0032259 97 48 0,000 0,19810223 0,21005371 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,2017846 0,21386541 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,2017846 0,21377267 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,2017846 0,21368 ! JNK cascade GO:0007254 106 49 0,000 0,2017846 0,21358742 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,2017846 0,21349492 ! regulation of action potential GO:0001508 102 50 0,000 0,20545016 0,21727911 ! regulation of ion transport GO:0043269 86 50 0,000 0,20545016 0,21718509 ! endocrine system development GO:0035270 109 50 0,000 0,20545016 0,21709115 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,20545016 0,21699729 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,20545016 0,21690352 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,20545016 0,21680982 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,20545016 0,21671621 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,20909899 0,22046993 ! peptide metabolic process GO:0006518 80 51 0,000 0,20909899 0,22037482 ! response to temperature stimulus GO:0009266 84 51 0,000 0,20909899 0,22027979 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,20909899 0,22018484 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,21273117 0,22391307 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,21273117 0,22381664 ! excretion GO:0007588 87 52 0,000 0,21273117 0,22372029 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,21273117 0,22362403 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,21273117 0,22352785 ! amino acid activation GO:0043038 98 52 0,000 0,21273117 0,22343175 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,21634677 0,22713156 ! inner ear development GO:0048839 89 53 0,000 0,21634677 0,227034 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,21634677 0,22693652 ! vesicle organization GO:0016050 127 53 0,000 0,21634677 0,22683912 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,21634677 0,22674181 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 102 53 0,000 0,21634677 0,22664457 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,21994586 0,23031622 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,21994586 0,23021754 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,21994586 0,23011895 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 0,000 0,21994586 0,23002044 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,21994586 0,22992201 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,21994586 0,22982367 ! RNA catabolic process GO:0006401 103 55 0,000 0,22352853 0,23346738 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,22352853 0,2333676 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,22352853 0,23326792 ! cell recognition GO:0008037 98 55 0,000 0,22352853 0,23316831 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,22352853 0,2330688 ! response to UV GO:0009411 120 55 0,000 0,22352853 0,23296936 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,22352853 0,23287002 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,22709484 0,23648452 ! glucose catabolic process GO:0006007 88 56 0,000 0,22709484 0,23638376 ! chloride transport GO:0006821 102 57 0,000 0,23064487 0,23997675 ! muscle fiber development GO:0048747 131 57 0,000 0,23064487 0,23987459 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,23064487 0,23977252 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,23064487 0,23967053 ! cellular polysaccharide metabolic process GO:0044264 93 58 0,000 0,2341787 0,24323918 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,2341787 0,24313581 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,2341787 0,24303252 ! aging GO:0007568 112 58 0,000 0,2341787 0,24292932 ! gastrulation GO:0007369 122 58 0,000 0,2341787 0,24282621 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,2341787 0,24272319 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,2341787 0,24262025 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,24119802 0,24978668 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,24119802 0,24968084 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,24468367 0,25318179 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,24468367 0,2530746 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,24468367 0,2529675 ! proton transport GO:0015992 117 61 0,000 0,24468367 0,2528605 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,24815341 0,25633775 ! mesoderm development GO:0007498 128 63 0,000 0,2516073 0,2597957 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,2516073 0,25968594 ! hydrogen transport GO:0006818 121 64 0,000 0,25504542 0,26312329 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,25504542 0,26301223 ! protein amino acid autophosphorylation GO:0046777 157 64 0,000 0,25504542 0,26290125 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,25846784 0,26631672 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,25846784 0,26620444 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,25846784 0,26609226 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,25846784 0,26598018 ! ear development GO:0043583 114 66 0,000 0,26187464 0,26937253 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,26187464 0,26925915 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,26187464 0,26914588 ! activation of MAPK activity GO:0000187 124 67 0,000 0,26526588 0,27251663 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,26526588 0,27240208 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,26864164 0,27575274 ! hexose catabolic process GO:0019320 113 68 0,000 0,26864164 0,27563692 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,26864164 0,27552121 ! regulation of lipase activity GO:0060191 137 68 0,000 0,26864164 0,27540559 ! single fertilization GO:0007338 83 69 0,000 0,27200198 0,27873357 ! cell redox homeostasis GO:0045454 114 70 0,000 0,27534697 0,28204304 ! germ cell development GO:0007281 133 70 0,000 0,27534697 0,28192483 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,27867669 0,28521456 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,27867669 0,28509512 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,27867669 0,28497579 ! carbohydrate transport GO:0008643 114 72 0,000 0,2819912 0,28824456 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,2819912 0,28812401 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,2819912 0,28800356 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,28529058 0,29125152 ! amino acid transport GO:0006865 148 74 0,000 0,28857488 0,29448139 ! transition metal ion transport GO:0000041 143 75 0,000 0,29184419 0,29769326 ! axon guidance GO:0007411 162 75 0,000 0,29184419 0,29756901 ! learning or memory GO:0007611 161 76 0,000 0,29509856 0,3007617 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,29509856 0,30063628 ! regulation of blood pressure GO:0008217 134 76 0,000 0,29509856 0,30051096 ! neurotransmitter transport GO:0006836 142 77 0,000 0,29833807 0,3036833 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,29833807 0,30355682 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,29833807 0,30343044 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,30156279 0,30658256 ! fertilization GO:0009566 99 78 0,000 0,30156279 0,30645503 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,30156279 0,3063276 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,30477277 0,30945963 ! muscle cell differentiation GO:0042692 178 81 0,000 0,31114881 0,31580247 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,31746674 0,32208108 ! exocytosis GO:0006887 153 83 0,000 0,31746674 0,32194738 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,31746674 0,32181379 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,31746674 0,32168032 ! inorganic anion transport GO:0015698 156 83 0,000 0,31746674 0,32154695 ! negative regulation of transport GO:0051051 164 85 0,000 0,32372707 0,32775186 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,32372707 0,32761609 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,32372707 0,32748043 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,32372707 0,32734488 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,3268358 0,33035162 ! regulation of lyase activity GO:0051339 169 86 0,000 0,3268358 0,330215 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,3268358 0,33007849 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,32993033 0,33306603 ! mitochondrion organization GO:0007005 159 87 0,000 0,32993033 0,33292846 ! alcohol catabolic process GO:0046164 142 87 0,000 0,32993033 0,332791 ! nucleosome assembly GO:0006334 126 87 0,000 0,32993033 0,33265365 ! cellular respiration GO:0045333 143 88 0,000 0,33301072 0,33562095 ! sensory perception of smell GO:0007608 117 88 0,000 0,33301072 0,33548255 ! chromatin assembly GO:0031497 128 88 0,000 0,33301072 0,33534426 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,33301072 0,33520609 ! cellular defense response GO:0006968 123 89 0,000 0,33607703 0,33815329 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,33912934 0,34108397 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,34216769 0,34399822 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,34519217 0,34689612 ! amine transport GO:0015837 181 93 0,000 0,34820282 0,34977775 ! positive regulation of MAP kinase activity GO:0043406 174 93 0,000 0,34820282 0,34963399 ! female pregnancy GO:0007565 166 94 0,000 0,35119972 0,35249832 ! sterol metabolic process GO:0016125 166 94 0,000 0,35119972 0,35235355 ! regulation of membrane potential GO:0042391 179 94 0,000 0,35119972 0,35220891 ! regulation of defense response GO:0031347 171 95 0,000 0,35418292 0,35505493 ! nucleosome organization GO:0034728 143 95 0,000 0,35418292 0,3549093 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,35418292 0,35476378 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,35418292 0,35461839 ! regulation of T cell activation GO:0050863 175 96 0,000 0,35715248 0,35744511 ! forebrain development GO:0030900 210 98 0,000 0,36305097 0,36319963 ! mRNA transport GO:0051028 185 100 0,000 0,36889565 0,36889565