pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/574-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of glycolysis GO:0045821 14 5 2,000 3,325E-07 8E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 7,912E-07 9,518E-04 ! regulation of DNA replication GO:0006275 101 56 4,000 1,102E-06 8,839E-04 ! positive regulation of cell migration GO:0030335 126 57 4,000 1,205E-06 7,248E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 1,265E-06 6,088E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 1,491E-06 5,981E-04 ! regulation of homeostatic process GO:0032844 134 62 4,000 1,839E-06 6,319E-04 ! ER overload response GO:0006983 12 8 2,000 1,849E-06 5,561E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,849E-06 4,943E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 2,032E-06 4,89E-04 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 2,032E-06 4,446E-04 ! positive regulation of cell motion GO:0051272 146 64 4,000 2,155E-06 4,321E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 2,767E-06 5,121E-04 ! regulation of glycolysis GO:0006110 21 9 2,000 2,767E-06 4,755E-04 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 2,000 2,767E-06 4,438E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 3,943E-06 5,93E-04 ! protein sumoylation GO:0016925 15 10 2,000 3,943E-06 5,581E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 3,943E-06 5,271E-04 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 3,943E-06 4,993E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 5,409E-06 6,507E-04 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 7,195E-06 8,244E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 9,332E-06 1,021E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of erythrocyte differentiation GO:0045646 44 14 2,000 1,185E-05 1,239E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 1,185E-05 1,188E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 1,418E-05 1,364E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 1,549E-05 1,433E-03 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 1,814E-05 1,617E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 2,000 2,198E-05 1,889E-03 ! regulation of angiogenesis GO:0045765 114 52 3,000 2,531E-05 2,1E-03 ! response to retinoic acid GO:0032526 26 18 2,000 2,631E-05 2,11E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 2,631E-05 2,042E-03 ! response to vitamin A GO:0033189 27 19 2,000 3,117E-05 2,344E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 3,117E-05 2,273E-03 ! response to vitamin GO:0033273 31 20 2,000 3,659E-05 2,589E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 3,659E-05 2,515E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 3,659E-05 2,445E-03 ! negative regulation of translation GO:0017148 29 20 2,000 3,659E-05 2,379E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 4,469E-05 2,83E-03 ! keratinization GO:0031424 28 22 2,000 4,919E-05 3,035E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 4,919E-05 2,959E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 5,643E-05 3,312E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 6,434E-05 3,686E-03 ! protein tetramerization GO:0051262 52 24 2,000 6,434E-05 3,6E-03 ! lung development GO:0030324 144 67 3,000 6,904E-05 3,775E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 7,295E-05 3,9E-03 ! respiratory tube development GO:0030323 150 70 3,000 8,197E-05 4,287E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 8,227E-05 4,211E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 8,227E-05 4,124E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 8,227E-05 4,039E-03 ! respiratory system development GO:0060541 153 72 3,000 9,152E-05 4,404E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 9,233E-05 4,356E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 1,041E-04 4,818E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,041E-04 4,728E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,041E-04 4,64E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,041E-04 4,556E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,041E-04 4,474E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,041E-04 4,396E-03 ! valine metabolic process GO:0006573 10 5 1,000 1,041E-04 4,32E-03 ! mRNA transcription GO:0009299 9 5 1,000 1,041E-04 4,247E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,041E-04 4,176E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,041E-04 4,108E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 1,148E-04 4,455E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 1,406E-04 5,368E-03 ! response to hypoxia GO:0001666 171 81 3,000 1,447E-04 5,441E-03 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,518E-04 5,618E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,547E-04 5,641E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 1,559E-04 5,598E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 1,559E-04 5,515E-03 ! male sex determination GO:0030238 15 6 1,000 1,559E-04 5,435E-03 ! monocyte differentiation GO:0030224 12 6 1,000 1,559E-04 5,358E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 1,559E-04 5,282E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,559E-04 5,209E-03 ! response to oxygen levels GO:0070482 176 83 3,000 1,591E-04 5,242E-03 ! DNA damage checkpoint GO:0000077 71 33 2,000 1,698E-04 5,521E-03 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 1,698E-04 5,447E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,178E-04 6,894E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,178E-04 6,804E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,178E-04 6,717E-03 ! mRNA stabilization GO:0048255 18 7 1,000 2,178E-04 6,632E-03 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 2,178E-04 6,549E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,178E-04 6,468E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,178E-04 6,39E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,178E-04 6,313E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 2,178E-04 6,237E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,178E-04 6,164E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 2,178E-04 6,092E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,178E-04 6,022E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,178E-04 5,954E-03 ! DNA integrity checkpoint GO:0031570 75 36 2,000 2,206E-04 5,965E-03 ! tissue remodeling GO:0048771 76 37 2,000 2,396E-04 6,404E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,396E-04 6,334E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 2,595E-04 6,786E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 2,595E-04 6,713E-03 ! carbohydrate homeostasis GO:0033500 53 38 2,000 2,595E-04 6,641E-03 GO:0042593|glucose homeostasis, ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 2,675E-04 6,774E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,897E-04 7,262E-03 ! succinate metabolic process GO:0006105 14 8 1,000 2,897E-04 7,187E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 2,897E-04 7,113E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,897E-04 7,042E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 2,897E-04 6,971E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,897E-04 6,902E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,897E-04 6,834E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,897E-04 6,768E-03 ! interphase GO:0051325 213 98 3,000 3,012E-04 6,969E-03 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 3,025E-04 6,931E-03 ! keratinocyte differentiation GO:0030216 62 41 2,000 3,256E-04 7,39E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 3,498E-04 7,865E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,717E-04 8,281E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 3,717E-04 8,205E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 3,717E-04 8,131E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 3,717E-04 8,058E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,717E-04 7,986E-03 ! phosphagen metabolic process GO:0006599 12 9 1,000 3,717E-04 7,915E-03 GO:0006600|creatine metabolic process, ! protein heterooligomerization GO:0051291 16 9 1,000 3,717E-04 7,845E-03 ! gas homeostasis GO:0033483 16 9 1,000 3,717E-04 7,777E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 3,717E-04 7,71E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 4,582E-04 9,422E-03 ! epidermal cell differentiation GO:0009913 68 46 2,000 4,582E-04 9,342E-03 ! pigmentation GO:0043473 100 46 2,000 4,582E-04 9,264E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 4,582E-04 9,187E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 4,637E-04 9,22E-03 ! lung alveolus development GO:0048286 26 10 1,000 4,637E-04 9,144E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 4,637E-04 9,07E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 4,637E-04 8,997E-03 ! apical protein localization GO:0045176 15 10 1,000 4,637E-04 8,925E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 4,637E-04 8,854E-03 ! mitochondrial transport GO:0006839 82 48 2,000 5,196E-04 9,844E-03 ! activation of caspase activity GO:0006919 84 48 2,000 5,196E-04 9,767E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,655E-04 0,01054751 ! detection of mechanical stimulus GO:0050982 22 11 1,000 5,655E-04 0,01046638 ! blood vessel remodeling GO:0001974 29 11 1,000 5,655E-04 0,01038648 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,655E-04 0,0103078 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,655E-04 0,01023029 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 5,655E-04 0,01015395 ! DNA methylation GO:0006306 19 11 1,000 5,655E-04 0,01007873 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 5,655E-04 0,01000462 ! regulation of embryonic development GO:0045995 27 11 1,000 5,655E-04 9,932E-03 ! regulation of cell shape GO:0008360 125 51 2,000 6,212E-04 0,01083061 ! membrane fusion GO:0006944 110 52 2,000 6,577E-04 0,01138419 ! positive regulation of growth GO:0045927 90 52 2,000 6,577E-04 0,01130288 ! virus-host interaction GO:0019048 29 12 1,000 6,772E-04 0,01155527 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 6,772E-04 0,01147389 GO:0050927|positive regulation of positive chemotaxis, ! asymmetric protein localization GO:0008105 20 12 1,000 6,772E-04 0,01139365 ! histone acetylation GO:0016573 26 12 1,000 6,772E-04 0,01131453 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 6,772E-04 0,0112365 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,772E-04 0,01115954 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 6,772E-04 0,01108362 ! response to UV GO:0009411 104 53 2,000 6,955E-04 0,01130679 ! positive regulation of caspase activity GO:0043280 95 55 2,000 7,753E-04 0,01251855 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 97 55 2,000 7,753E-04 0,01243509 ! regulation of chemokine production GO:0032642 18 13 1,000 7,986E-04 0,0127248 ! Golgi organization GO:0007030 24 13 1,000 7,986E-04 0,01264109 ! response to X-ray GO:0010165 25 13 1,000 7,986E-04 0,01255847 ! regulation of cellular pH GO:0030641 22 13 1,000 7,986E-04 0,01247692 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,986E-04 0,01239642 ! regulation of mRNA stability GO:0043488 31 13 1,000 7,986E-04 0,01231696 ! embryonic placenta development GO:0001892 23 13 1,000 7,986E-04 0,0122385 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 9,297E-04 0,01415782 ! response to gamma radiation GO:0010332 28 14 1,000 9,297E-04 0,01406877 ! male genitalia development GO:0030539 24 14 1,000 9,297E-04 0,01398084 ! regulation of RNA stability GO:0043487 32 14 1,000 9,297E-04 0,013894 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 9,994E-04 0,01484286 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,049E-03 0,0154784 ! ER-associated protein catabolic process GO:0030433 24 15 1,000 1,07E-03 0,01570493 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,07E-03 0,01560975 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,07E-03 0,01551572 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,07E-03 0,01542281 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,07E-03 0,01533101 ! muscle maintenance GO:0046716 26 15 1,000 1,07E-03 0,01524029 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 1,07E-03 0,01515064 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,221E-03 0,0171773 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 1,221E-03 0,01707743 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,221E-03 0,01697871 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,221E-03 0,01688114 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 1,261E-03 0,01733382 ! activation of MAPK activity GO:0000187 115 67 2,000 1,376E-03 0,01881386 ! heart looping GO:0001947 30 17 1,000 1,381E-03 0,01876785 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,381E-03 0,01866241 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,381E-03 0,01855815 ! genitalia development GO:0048806 30 17 1,000 1,381E-03 0,01845505 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,381E-03 0,01835309 ! neural crest cell migration GO:0001755 37 17 1,000 1,381E-03 0,01825225 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 1,381E-03 0,01815251 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,381E-03 0,01805385 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,381E-03 0,01795627 ! cell cycle checkpoint GO:0000075 137 69 2,000 1,498E-03 0,01937932 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,55E-03 0,01994243 ! regulation of caspase activity GO:0043281 122 72 2,000 1,693E-03 0,02167162 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 1,693E-03 0,02155696 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 1,729E-03 0,02189024 ! cellular response to unfolded protein GO:0034620 33 19 1,000 1,729E-03 0,02177563 GO:0030968|endoplasmic reticulum unfolded protein response, ! plasma membrane fusion GO:0045026 28 19 1,000 1,729E-03 0,02166221 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,729E-03 0,02154997 ! cellular pigmentation GO:0033059 36 19 1,000 1,729E-03 0,02143889 ! G1 phase GO:0051318 40 19 1,000 1,729E-03 0,02132895 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 1,832E-03 0,02248812 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,917E-03 0,02340859 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,917E-03 0,02329036 ! response to alkaloid GO:0043279 38 20 1,000 1,917E-03 0,02317332 ! cellular response to starvation GO:0009267 33 20 1,000 1,917E-03 0,02305746 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 1,917E-03 0,02294274 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 1,917E-03 0,02282916 ! peptidyl-serine modification GO:0018209 43 20 1,000 1,917E-03 0,02271671 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,917E-03 0,02260535 ! regulation of catabolic process GO:0009894 161 76 2,000 1,977E-03 0,02320798 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 2,114E-03 0,02468994 ! cell aging GO:0007569 44 21 1,000 2,114E-03 0,02457066 ! DNA modification GO:0006304 34 21 1,000 2,114E-03 0,02445253 ! positive regulation of locomotion GO:0040017 39 21 1,000 2,114E-03 0,02433554 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! protein oligomerization GO:0051259 139 78 2,000 2,13E-03 0,0244021 ! regulation of peptidase activity GO:0052547 134 79 2,000 2,209E-03 0,025186 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 2,209E-03 0,0250672 ! protein import into nucleus GO:0006606 158 80 2,000 2,289E-03 0,02586087 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 2,32E-03 0,02608834 ! regulation of chemotaxis GO:0050920 40 22 1,000 2,32E-03 0,025967 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 2,32E-03 0,02584678 ! apoptotic nuclear changes GO:0030262 32 22 1,000 2,32E-03 0,02572767 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,32E-03 0,02560965 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 2,32E-03 0,02549271 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 2,372E-03 0,02594015 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 2,000 2,372E-03 0,02582278 ! response to drug GO:0042493 143 82 2,000 2,456E-03 0,02662019 ! response to nutrient GO:0007584 125 82 2,000 2,456E-03 0,02650081 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 2,536E-03 0,02723963 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 2,536E-03 0,02711857 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 2,536E-03 0,02699858 ! sex determination GO:0007530 47 23 1,000 2,536E-03 0,02687964 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,536E-03 0,02676175 ! negative regulation of growth GO:0045926 155 84 2,000 2,63E-03 0,02763603 ! response to unfolded protein GO:0006986 131 85 2,000 2,72E-03 0,02845581 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,761E-03 0,02875455 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,761E-03 0,02863061 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 2,761E-03 0,02850773 ! regulation of behavior GO:0050795 43 24 1,000 2,761E-03 0,02838591 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,761E-03 0,02826512 ! mitochondrion organization GO:0007005 148 86 2,000 2,812E-03 0,0286675 ! protein localization in nucleus GO:0034504 176 87 2,000 2,906E-03 0,0294969 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 2,994E-03 0,03027156 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,994E-03 0,0301449 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 2,994E-03 0,0300193 ! vasculogenesis GO:0001570 46 25 1,000 2,994E-03 0,02989474 ! negative regulation of DNA replication GO:0008156 42 25 1,000 2,994E-03 0,02977121 ! response to starvation GO:0042594 42 25 1,000 2,994E-03 0,02964869 ! neural crest cell development GO:0014032 54 25 1,000 2,994E-03 0,02952718 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 2,994E-03 0,02940666 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,994E-03 0,02928712 ! somitogenesis GO:0001756 43 25 1,000 2,994E-03 0,02916855 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,994E-03 0,02905094 ! positive regulation of protein modification process GO:0031401 136 88 2,000 3,001E-03 0,02899827 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 3,098E-03 0,02981989 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 3,237E-03 0,03102997 ! response to protein stimulus GO:0051789 149 91 2,000 3,299E-03 0,03149882 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 3,489E-03 0,03317721 ! protein amino acid acylation GO:0043543 55 27 1,000 3,489E-03 0,03304659 ! fat cell differentiation GO:0045444 50 27 1,000 3,489E-03 0,03291699 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,489E-03 0,03278841 ! base-excision repair GO:0006284 41 27 1,000 3,489E-03 0,03266083 ! regulation of chromosome organization GO:0033044 42 27 1,000 3,489E-03 0,03253424 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 3,508E-03 0,03258371 ! dendrite development GO:0016358 59 28 1,000 3,749E-03 0,03469392 ! leukocyte differentiation GO:0002521 202 96 2,000 3,835E-03 0,03535268 ! regulation of pH GO:0006885 43 29 1,000 4,018E-03 0,03690129 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 4,018E-03 0,03676098 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 4,018E-03 0,03662174 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 4,296E-03 0,03900698 ! response to heat GO:0009408 50 30 1,000 4,296E-03 0,03886034 ! cell cycle arrest GO:0007050 213 100 2,000 4,3E-03 0,03874612 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 4,583E-03 0,04114333 ! collagen metabolic process GO:0032963 45 31 1,000 4,583E-03 0,04099038 ! response to ionizing radiation GO:0010212 65 32 1,000 4,878E-03 0,04346922 ! response to mechanical stimulus GO:0009612 57 32 1,000 4,878E-03 0,04330881 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 5,494E-03 0,0485986 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 5,494E-03 0,04842058 ! placenta development GO:0001890 53 34 1,000 5,494E-03 0,04824386 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,494E-03 0,04806843 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,815E-03 0,05068984 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 5,815E-03 0,05050684 ! odontogenesis GO:0042476 66 35 1,000 5,815E-03 0,05032516 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,815E-03 0,05014479 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,815E-03 0,0499657 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 6,144E-03 0,05260545 ! embryonic organ development GO:0048568 57 36 1,000 6,144E-03 0,05241891 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,481E-03 0,05510209 ! glycogen metabolic process GO:0005977 61 37 1,000 6,481E-03 0,05490806 ! nucleus organization GO:0006997 67 38 1,000 6,827E-03 0,05763346 ! glucan metabolic process GO:0044042 62 38 1,000 6,827E-03 0,05743194 GO:0006073|cellular glucan metabolic process, ! ear morphogenesis GO:0042471 60 39 1,000 7,181E-03 0,06019836 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 7,181E-03 0,05998934 ! segmentation GO:0035282 67 39 1,000 7,181E-03 0,05978177 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 7,543E-03 0,06257911 ! mesenchymal cell development GO:0014031 87 40 1,000 7,543E-03 0,06236406 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cellular amide metabolic process GO:0043603 67 41 1,000 7,913E-03 0,06520012 ! T cell differentiation GO:0030217 81 41 1,000 7,913E-03 0,0649776 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 8,291E-03 0,06785129 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 8,291E-03 0,06762129 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 8,291E-03 0,06739284 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 8,291E-03 0,06716592 ! energy reserve metabolic process GO:0006112 74 43 1,000 8,677E-03 0,07005818 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 8,677E-03 0,06982387 ! male sex differentiation GO:0046661 76 44 1,000 9,071E-03 0,07275161 ! double-strand break repair GO:0006302 81 44 1,000 9,071E-03 0,07250991 ! biopolymer methylation GO:0043414 84 44 1,000 9,071E-03 0,07226981 ! B cell differentiation GO:0030183 107 44 1,000 9,071E-03 0,07203129 ! JAK-STAT cascade GO:0007259 71 44 1,000 9,071E-03 0,07179435 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 9,473E-03 0,07472976 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 9,473E-03 0,07448555 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 9,883E-03 0,07745438 ! negative regulation of cell migration GO:0030336 115 46 1,000 9,883E-03 0,07720291 ! positive regulation of protein transport GO:0051222 72 46 1,000 9,883E-03 0,07695306 ! response to calcium ion GO:0051592 81 47 1,000 0,01030054 0,0799455 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01030054 0,07968844 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01030054 0,07943303 ! methylation GO:0032259 90 47 1,000 0,01030054 0,07917925 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,0107258 0,0821856 ! cellular component disassembly GO:0022411 86 48 1,000 0,0107258 0,08192469 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01115872 0,08496166 ! response to temperature stimulus GO:0009266 76 49 1,000 0,01115872 0,08469364 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01115872 0,08442731 ! histone modification GO:0016570 91 50 1,000 0,01159925 0,08748525 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01159925 0,08721186 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01159925 0,08694017 ! positive regulation of binding GO:0051099 78 51 1,000 0,01204733 0,09001827 ! chromatin remodeling GO:0006338 109 51 1,000 0,01204733 0,08973958 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,01204733 0,0894626 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01250292 0,09256007 ! amino acid activation GO:0043038 92 52 1,000 0,01250292 0,09227614 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 0,01250292 0,09199395 ! regulation of translational initiation GO:0006446 82 53 1,000 0,01296595 0,09511002 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01296595 0,09482093 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01343639 0,09796348 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01391417 0,10114043 ! aging GO:0007568 103 55 1,000 0,01391417 0,10083579 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01391417 0,10053298 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,01391417 0,10023199 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01439924 0,10341662 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,01489155 0,10663416 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01489155 0,10631773 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,01489155 0,10600318 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01539106 0,10923565 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,0158977 0,11249964 ! DNA catabolic process GO:0006308 86 59 1,000 0,0158977 0,11216972 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01616541 0,11372506 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01616541 0,1133935 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01616541 0,11306387 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01616541 0,11273615 ! neuron fate determination GO:0048664 7 5 0,000 0,01616541 0,11241032 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01616541 0,11208637 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01616541 0,11176428 ! polyol transport GO:0015791 12 5 0,000 0,01616541 0,11144404 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01616541 0,11112563 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01616541 0,11080903 ! response to superoxide GO:0000303 10 5 0,000 0,01616541 0,11049424 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01616541 0,11018122 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01616541 0,10986997 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01616541 0,10956048 ! female meiosis GO:0007143 7 5 0,000 0,01616541 0,10925273 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01616541 0,1089467 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01616541 0,10864238 ! cobalt ion transport GO:0006824 11 5 0,000 0,01616541 0,10833975 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01616541 0,10803881 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01616541 0,10773953 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01616541 0,10744191 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01616541 0,10714593 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01616541 0,10685157 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01616541 0,10655882 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01616541 0,10626768 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01616541 0,10597812 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01616541 0,10569014 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01616541 0,10540372 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01616541 0,10511884 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01616541 0,1048355 ! negative chemotaxis GO:0050919 14 5 0,000 0,01616541 0,10455369 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01616541 0,10427338 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01616541 0,10399457 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01616541 0,10371726 ! behavioral response to pain GO:0048266 9 5 0,000 0,01616541 0,10344141 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01616541 0,10316703 ! Notch receptor processing GO:0007220 8 5 0,000 0,01616541 0,1028941 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01616541 0,10262261 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01616541 0,10235256 ! micturition GO:0060073 9 5 0,000 0,01616541 0,10208391 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01616541 0,10181668 ! copulation GO:0007620 9 5 0,000 0,01616541 0,10155084 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01616541 0,10128638 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01616541 0,1010233 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01616541 0,10076158 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01616541 0,10050122 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01616541 0,10024219 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01616541 0,0999845 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01616541 0,09972813 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01616541 0,09947307 ! grooming behavior GO:0007625 6 5 0,000 0,01616541 0,09921931 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01616541 0,09896685 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01616541 0,09871566 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01616541 0,09846575 ! response to protozoan GO:0001562 10 5 0,000 0,01616541 0,0982171 ! lymph vessel development GO:0001945 10 5 0,000 0,01616541 0,0979697 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01616541 0,09772355 ! endochondral ossification GO:0001958 16 5 0,000 0,01616541 0,09747862 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01616541 0,09723493 ! parathyroid gland development GO:0060017 13 5 0,000 0,01616541 0,09699245 ! anagen GO:0042640 6 5 0,000 0,01616541 0,09675117 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01616541 0,09651109 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01616541 0,09627221 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01616541 0,0960345 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01616541 0,09579796 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01616541 0,09556258 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01616541 0,09532836 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01616541 0,09509528 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01616541 0,09486334 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01616541 0,09463253 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01616541 0,09440284 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01616541 0,09417426 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01616541 0,09394679 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01616541 0,09372041 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01616541 0,09349512 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01616541 0,09327091 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01616541 0,09304778 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01616541 0,09282571 ! histidine catabolic process GO:0006548 6 5 0,000 0,01616541 0,09260469 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01616541 0,09238473 ! microvillus organization GO:0032528 7 5 0,000 0,01616541 0,09216581 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01616541 0,09194792 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01616541 0,09173106 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01616541 0,09151523 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01616541 0,0913004 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01616541 0,09108658 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01616541 0,09087376 ! polyol catabolic process GO:0046174 7 5 0,000 0,01616541 0,09066194 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01616541 0,0904511 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01616541 0,09024123 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01616541 0,09003234 ! muscle cell migration GO:0014812 8 5 0,000 0,01616541 0,08982441 ! mitochondrial fission GO:0000266 8 5 0,000 0,01616541 0,08961744 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01616541 0,08941143 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01616541 0,08920636 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01616541 0,08900222 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01616541 0,08879902 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01616541 0,08859674 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01616541 0,08839539 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01616541 0,08819495 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01616541 0,08799541 ! response to food GO:0032094 6 5 0,000 0,01616541 0,08779677 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01616541 0,08759903 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01616541 0,08740218 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01616541 0,08720621 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01616541 0,08701112 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01616541 0,0868169 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01616541 0,08662354 ! forebrain neuron development GO:0021884 13 5 0,000 0,01616541 0,08643105 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01616541 0,0862394 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01616541 0,08604861 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01616541 0,08585866 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01616541 0,08566954 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01616541 0,08548125 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01616541 0,0852938 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01616541 0,08510716 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01616541 0,08492133 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01616541 0,08473632 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01616541 0,08455211 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01616541 0,0843687 ! basic amino acid transport GO:0015802 11 5 0,000 0,01616541 0,08418608 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01616541 0,08400426 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01616541 0,08382321 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01616541 0,08364295 ! depyrimidination GO:0045008 10 5 0,000 0,01616541 0,08346346 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01616541 0,08328473 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01616541 0,08310678 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01616541 0,08292958 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01616541 0,08275313 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01616541 0,08257743 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01616541 0,08240248 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01616541 0,08222827 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01616541 0,08205479 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01616541 0,08188204 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01616541 0,08171002 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01616541 0,08153872 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01616541 0,08136814 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01616541 0,08119827 ! response to arsenic GO:0046685 10 5 0,000 0,01616541 0,08102911 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01616541 0,08086065 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01616541 0,08069289 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01616541 0,08052582 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01616541 0,08035944 ! response to cadmium ion GO:0046686 7 5 0,000 0,01616541 0,08019375 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01616541 0,08002875 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01616541 0,07986442 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01616541 0,07970076 ! decidualization GO:0046697 11 5 0,000 0,01616541 0,07953777 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01616541 0,07937545 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01616541 0,07921379 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01616541 0,07905279 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01616541 0,07889244 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01616541 0,07873273 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01616541 0,07857368 ! neural tube patterning GO:0021532 7 5 0,000 0,01616541 0,07841526 ! embryonic cleavage GO:0040016 6 5 0,000 0,01616541 0,07825749 ! peroxisome fission GO:0016559 5 5 0,000 0,01616541 0,07810034 ! histone demethylation GO:0016577 10 5 0,000 0,01616541 0,07794383 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01616541 0,07778794 ! mitotic recombination GO:0006312 9 5 0,000 0,01616541 0,07763268 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01616541 0,07747803 ! metaphase plate congression GO:0051310 7 5 0,000 0,01616541 0,077324 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01616541 0,07717058 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01616541 0,07701776 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01616541 0,07686556 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01616541 0,07671395 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01616541 0,07656294 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01616541 0,07641252 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01616541 0,07626269 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01616541 0,07611345 ! plasminogen activation GO:0031639 5 5 0,000 0,01616541 0,07596479 ! B cell homeostasis GO:0001782 13 5 0,000 0,01616541 0,07581671 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01616541 0,0756692 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01616541 0,07552227 ! metaphase GO:0051323 8 5 0,000 0,01616541 0,07537591 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01616541 0,07523012 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01616541 0,07508489 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01616541 0,07494021 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01616541 0,0747961 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01616541 0,07465254 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01616541 0,07450952 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01616541 0,07436706 ! response to redox state GO:0051775 5 5 0,000 0,01616541 0,07422514 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01616541 0,07408375 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01616541 0,07394291 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01616541 0,0738026 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01616541 0,07366282 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01616541 0,07352357 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01616541 0,07338485 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01616541 0,07324665 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01616541 0,07310897 ! striatum development GO:0021756 9 5 0,000 0,01616541 0,0729718 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01616541 0,07283515 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01616541 0,07269901 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01616541 0,07256338 ! glial cell migration GO:0008347 11 5 0,000 0,01616541 0,07242825 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01616541 0,07229363 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01616541 0,0721595 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01616541 0,07202587 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01616541 0,07189274 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01616541 0,07176009 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01616541 0,07162794 ! neuroprotection GO:0043526 6 5 0,000 0,01616541 0,07149627 ! neural plate development GO:0001840 8 5 0,000 0,01616541 0,07136508 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01616541 0,07123438 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01616541 0,07110415 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01616541 0,0709744 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01616541 0,07084512 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01616541 0,07071631 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01616541 0,07058797 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01616541 0,07046009 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01616541 0,07033268 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01616541 0,07020572 ! spindle assembly GO:0051225 6 5 0,000 0,01616541 0,07007923 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01616541 0,06995319 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01616541 0,0698276 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01616541 0,06970246 ! drug metabolic process GO:0017144 6 5 0,000 0,01616541 0,06957777 ! stem cell division GO:0017145 11 5 0,000 0,01616541 0,06945352 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01616541 0,06932972 ! organ regeneration GO:0031100 7 5 0,000 0,01616541 0,06920635 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01616541 0,06908343 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01616541 0,06896094 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01616541 0,06883889 ! mesoderm development GO:0007498 119 61 1,000 0,01693221 0,07197686 ! ear development GO:0043583 103 62 1,000 0,01745997 0,07408942 ! viral reproductive process GO:0022415 126 62 1,000 0,01745997 0,07395898 ! detection of external stimulus GO:0009581 91 63 1,000 0,01799467 0,07608996 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,01908469 0,08055749 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01936731 0,08160728 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01936731 0,08146461 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01936731 0,08132244 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01936731 0,08118076 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01936731 0,08103958 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01936731 0,08089888 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01936731 0,08075868 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01936731 0,08061896 ! sleep GO:0030431 13 6 0,000 0,01936731 0,08047972 ! response to oxygen radical GO:0000305 11 6 0,000 0,01936731 0,08034096 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01936731 0,08020268 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01936731 0,08006487 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01936731 0,07992754 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01936731 0,07979068 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01936731 0,07965428 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01936731 0,07951836 ! forebrain regionalization GO:0021871 8 6 0,000 0,01936731 0,07938289 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01936731 0,07924789 ! male meiosis GO:0007140 7 6 0,000 0,01936731 0,07911334 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01936731 0,07897925 ! response to zinc ion GO:0010043 9 6 0,000 0,01936731 0,07884561 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01936731 0,07871243 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01936731 0,07857969 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01936731 0,0784474 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01936731 0,07831556 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01936731 0,07818416 ! malate metabolic process GO:0006108 11 6 0,000 0,01936731 0,07805319 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01936731 0,07792267 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01936731 0,07779258 ! protein refolding GO:0042026 15 6 0,000 0,01936731 0,07766293 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01936731 0,0775337 ! opsonization GO:0008228 8 6 0,000 0,01936731 0,07740491 ! mating behavior GO:0007617 7 6 0,000 0,01936731 0,07727654 ! neuron remodeling GO:0016322 15 6 0,000 0,01936731 0,0771486 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01936731 0,07702109 ! equilibrioception GO:0050957 14 6 0,000 0,01936731 0,07689399 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01936731 0,07676731 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01936731 0,07664105 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01936731 0,0765152 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01936731 0,07638976 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01936731 0,07626474 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01936731 0,07614013 ! toxin metabolic process GO:0009404 11 6 0,000 0,01936731 0,07601592 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01936731 0,07589211 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01936731 0,07576871 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01936731 0,07564571 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01936731 0,07552311 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01936731 0,0754009 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01936731 0,07527909 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01936731 0,07515767 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01936731 0,07503665 ! thymic T cell selection GO:0045061 12 6 0,000 0,01936731 0,07491601 ! protein lipoylation GO:0009249 10 6 0,000 0,01936731 0,07479576 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01936731 0,07467589 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01936731 0,07455641 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01936731 0,07443731 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01936731 0,07431859 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01936731 0,07420025 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01936731 0,07408228 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01936731 0,07396469 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01936731 0,07384747 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01936731 0,07373063 ! hyperosmotic response GO:0006972 9 6 0,000 0,01936731 0,07361415 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01936731 0,07349804 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01936731 0,07338229 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01936731 0,07326691 ! urea metabolic process GO:0019627 7 6 0,000 0,01936731 0,07315189 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01936731 0,07303724 ! neutrophil activation GO:0042119 8 6 0,000 0,01936731 0,07292294 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01936731 0,07280899 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01936731 0,07269541 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01936731 0,07258218 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01936731 0,07246929 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01936731 0,07235676 ! neuron apoptosis GO:0051402 9 6 0,000 0,01936731 0,07224458 ! nucleoside salvage GO:0043174 9 6 0,000 0,01936731 0,07213275 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01936731 0,07202126 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01936731 0,07191012 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01936731 0,07179932 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01936731 0,07168886 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01936731 0,07157874 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01936731 0,07146895 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01936731 0,0713595 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01936731 0,07125039 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01936731 0,07114161 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01936731 0,07103317 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01936731 0,07092505 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01936731 0,07081726 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01936731 0,0707098 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01936731 0,07060266 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01936731 0,07049585 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01936731 0,07038936 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 0,000 0,01936731 0,07028319 ! response to UV-C GO:0010225 11 6 0,000 0,01936731 0,07017734 ! astrocyte development GO:0014002 15 6 0,000 0,01936731 0,07007181 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01936731 0,0699666 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01936731 0,0698617 ! interaction with symbiont GO:0051702 13 6 0,000 0,01936731 0,06975712 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01936731 0,06965285 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01936731 0,06954889 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01936731 0,06944524 ! response to copper ion GO:0046688 10 6 0,000 0,01936731 0,0693419 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01936731 0,06923887 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01936731 0,06913614 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01936731 0,06903371 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01936731 0,06893159 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01936731 0,06882977 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01936731 0,06872825 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01936731 0,06862703 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01936731 0,06852611 ! hair follicle maturation GO:0048820 7 6 0,000 0,01936731 0,06842549 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01936731 0,06832516 ! Schwann cell development GO:0014044 15 6 0,000 0,01936731 0,06822512 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01936731 0,06812538 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01936731 0,06802592 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01936731 0,06792676 ! subpallium development GO:0021544 10 6 0,000 0,01936731 0,06782788 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01936731 0,0677293 ! histone ubiquitination GO:0016574 8 6 0,000 0,01936731 0,067631 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01936731 0,06753298 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01936731 0,06743525 ! G2 phase GO:0051319 16 6 0,000 0,01936731 0,0673378 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01936731 0,06724063 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01936731 0,06714374 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01936731 0,06704713 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01936731 0,0669508 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01936731 0,06685474 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01936731 0,06675896 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01936731 0,06666346 ! receptor internalization GO:0031623 10 6 0,000 0,01936731 0,06656822 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01936731 0,06647326 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01936731 0,06637857 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01936731 0,06628415 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01936731 0,06619 ! protein deubiquitination GO:0016579 14 6 0,000 0,01936731 0,06609611 ! protein destabilization GO:0031648 9 6 0,000 0,01936731 0,06600249 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01936731 0,06590913 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01936731 0,06581604 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01936731 0,06572321 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01936731 0,06563064 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01936731 0,06553834 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01936731 0,06544629 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01936731 0,0653545 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01936731 0,06526296 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01936731 0,06517169 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01936731 0,06508067 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01936731 0,0649899 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01936731 0,06489938 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01936731 0,06480912 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01936731 0,06471911 ! catecholamine transport GO:0051937 9 6 0,000 0,01936731 0,06462934 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01936731 0,06453983 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01936731 0,06445056 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01936731 0,06436154 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01936731 0,06427277 ! maternal placenta development GO:0001893 12 6 0,000 0,01936731 0,06418424 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01936731 0,06409595 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01936731 0,06400791 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01936731 0,06392011 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01936731 0,06383254 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01936731 0,06374522 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01936731 0,06365814 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01936731 0,06357129 ! extracellular matrix organization GO:0030198 133 66 1,000 0,01963991 0,06437823 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,02020187 0,0661302 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02020187 0,06604035 ! adaptive immune response GO:0002250 119 67 1,000 0,02020187 0,06595074 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,02077052 0,06771527 ! negative regulation of cell size GO:0045792 134 69 1,000 0,02134582 0,06949666 ! B cell activation GO:0042113 160 71 1,000 0,02251614 0,07320789 ! tRNA transcription GO:0009304 14 7 0,000 0,0225589 0,07324794 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0225589 0,07314923 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0225589 0,07305077 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0225589 0,07295259 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,0225589 0,07285466 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0225589 0,072757 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0225589 0,07265961 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0225589 0,07256247 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0225589 0,07246559 ! prostate gland development GO:0030850 13 7 0,000 0,0225589 0,07236897 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0225589 0,0722726 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0225589 0,0721765 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0225589 0,07208064 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0225589 0,07198505 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0225589 0,0718897 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0225589 0,07179461 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0225589 0,07169977 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,0225589 0,07160518 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0225589 0,07151084 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0225589 0,07141674 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0225589 0,0713229 ! glycolipid transport GO:0046836 10 7 0,000 0,0225589 0,0712293 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0225589 0,07113594 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,0225589 0,07104283 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0225589 0,07094997 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0225589 0,07085734 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0225589 0,07076496 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0225589 0,07067282 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0225589 0,07058092 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0225589 0,07048925 ! pericardium development GO:0060039 14 7 0,000 0,0225589 0,07039783 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0225589 0,07030664 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0225589 0,07021569 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0225589 0,07012497 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0225589 0,07003448 ! lipoprotein transport GO:0042953 14 7 0,000 0,0225589 0,06994423 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0225589 0,06985421 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0225589 0,06976443 ! rhythmic behavior GO:0007622 15 7 0,000 0,0225589 0,06967487 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0225589 0,06958554 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0225589 0,06949645 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0225589 0,06940758 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0225589 0,06931893 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0225589 0,06923052 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0225589 0,06914232 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0225589 0,06905436 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0225589 0,06896661 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0225589 0,06887909 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0225589 0,06879179 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0225589 0,06870472 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0225589 0,06861786 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0225589 0,06853122 ! spinal cord patterning GO:0021511 13 7 0,000 0,0225589 0,0684448 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0225589 0,0683586 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0225589 0,06827261 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0225589 0,06818684 ! adrenal gland development GO:0030325 17 7 0,000 0,0225589 0,06810129 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0225589 0,06801595 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0225589 0,06793082 ! ovulation GO:0030728 9 7 0,000 0,0225589 0,06784591 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0225589 0,0677612 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0225589 0,06767671 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0225589 0,06759243 ! microtubule nucleation GO:0007020 20 7 0,000 0,0225589 0,06750836 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0225589 0,0674245 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0225589 0,06734085 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0225589 0,0672574 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0225589 0,06717416 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0225589 0,06709113 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0225589 0,0670083 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0225589 0,06692568 ! galactose metabolic process GO:0006012 13 7 0,000 0,0225589 0,06684326 ! vesicle fusion GO:0006906 17 7 0,000 0,0225589 0,06676104 ! response to dietary excess GO:0002021 8 7 0,000 0,0225589 0,06667902 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0225589 0,06659721 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0225589 0,06651559 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0225589 0,06643418 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0225589 0,06635296 ! organ growth GO:0035265 15 7 0,000 0,0225589 0,06627195 ! purine salvage GO:0043101 10 7 0,000 0,0225589 0,06619113 ! nucleoside transport GO:0015858 8 7 0,000 0,0225589 0,06611051 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0225589 0,06603008 ! parturition GO:0007567 14 7 0,000 0,0225589 0,06594985 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0225589 0,06586981 ! rRNA modification GO:0000154 14 7 0,000 0,0225589 0,06578997 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0225589 0,06571032 ! spindle checkpoint GO:0031577 15 7 0,000 0,0225589 0,06563086 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0225589 0,0655516 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0225589 0,06547253 ! macrophage differentiation GO:0030225 11 7 0,000 0,0225589 0,06539364 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0225589 0,06531495 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0225589 0,06523645 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0225589 0,06515813 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0225589 0,06508001 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0225589 0,06500207 ! fibrinolysis GO:0042730 10 7 0,000 0,0225589 0,06492431 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0225589 0,06484674 ! eating behavior GO:0042755 7 7 0,000 0,0225589 0,06476936 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0225589 0,06469216 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0225589 0,06461515 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0225589 0,06453832 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0225589 0,06446167 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,0225589 0,0643852 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0225589 0,06430892 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0225589 0,06423281 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0225589 0,06415689 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0225589 0,06408114 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0225589 0,06400557 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0225589 0,06393018 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0225589 0,06385497 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0225589 0,06377994 ! regulation of meiosis GO:0040020 12 7 0,000 0,0225589 0,06370508 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,0225589 0,06363039 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0225589 0,06355588 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0225589 0,06348155 ! transcription termination GO:0006353 13 7 0,000 0,0225589 0,06340739 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0225589 0,0633334 ! anaphase GO:0051322 17 7 0,000 0,0225589 0,06325959 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0225589 0,06318594 ! axonal fasciculation GO:0007413 18 7 0,000 0,0225589 0,06311247 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0225589 0,06303917 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0225589 0,06296604 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0225589 0,06289308 ! diuresis GO:0030146 12 7 0,000 0,0225589 0,06282028 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0225589 0,06274766 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0225589 0,0626752 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0225589 0,06260291 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0225589 0,06253079 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0225589 0,06245883 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0225589 0,06238704 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0225589 0,06231541 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0225589 0,06224395 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0225589 0,06217265 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0225589 0,06210152 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0225589 0,06203054 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0225589 0,06195973 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0225589 0,06188908 ! lymph node development GO:0048535 10 7 0,000 0,0225589 0,06181859 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0225589 0,06174827 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0225589 0,0616781 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0225589 0,06160809 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0225589 0,06153824 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0225589 0,06146854 ! adult feeding behavior GO:0008343 9 7 0,000 0,0225589 0,06139901 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0225589 0,06132963 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0225589 0,06126041 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0225589 0,06119135 ! muscle adaptation GO:0043500 14 7 0,000 0,0225589 0,06112244 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0225589 0,06105368 ! retina homeostasis GO:0001895 12 7 0,000 0,0225589 0,06098508 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0225589 0,06091664 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0225589 0,06084835 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0225589 0,06078021 ! protein prenylation GO:0018342 18 7 0,000 0,0225589 0,06071222 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,0225589 0,06064439 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,0225589 0,0605767 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0225589 0,06050917 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02432026 0,06516096 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,02493441 0,06673213 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02493441 0,06665798 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,02555487 0,06824085 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02574021 0,0686596 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02574021 0,06858356 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02574021 0,06850769 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02574021 0,068432 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02574021 0,06835646 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02574021 0,0682811 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02574021 0,0682059 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02574021 0,06813086 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02574021 0,068056 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02574021 0,06798129 ! meiotic prophase I GO:0007128 13 8 0,000 0,02574021 0,06790675 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02574021 0,06783237 ! oligopeptide transport GO:0006857 15 8 0,000 0,02574021 0,06775816 ! UTP metabolic process GO:0046051 8 8 0,000 0,02574021 0,0676841 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02574021 0,06761021 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02574021 0,06753648 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02574021 0,06746291 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02574021 0,06738951 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02574021 0,06731626 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02574021 0,06724317 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02574021 0,06717023 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02574021 0,06709746 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02574021 0,06702484 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02574021 0,06695238 ! reflex GO:0060004 16 8 0,000 0,02574021 0,06688008 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02574021 0,06680793 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02574021 0,06673594 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02574021 0,06666411 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02574021 0,06659243 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02574021 0,0665209 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02574021 0,06644952 ! pigment granule organization GO:0048753 16 8 0,000 0,02574021 0,0663783 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02574021 0,06630723 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02574021 0,06623632 ! histidine metabolic process GO:0006547 16 8 0,000 0,02574021 0,06616555 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02574021 0,06609494 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02574021 0,06602447 ! glycine catabolic process GO:0006546 13 8 0,000 0,02574021 0,06595416 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02574021 0,065884 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02574021 0,06581398 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02574021 0,06574411 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02574021 0,0656744 ! melanin metabolic process GO:0006582 15 8 0,000 0,02574021 0,06560483 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02574021 0,0655354 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02574021 0,06546613 ! macrophage activation GO:0042116 12 8 0,000 0,02574021 0,065397 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02574021 0,06532801 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02574021 0,06525917 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02574021 0,06519048 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02574021 0,06512193 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02574021 0,06505352 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02574021 0,06498526 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02574021 0,06491714 ! osteoblast development GO:0002076 16 8 0,000 0,02574021 0,06484917 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02574021 0,06478133 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02574021 0,06471364 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02574021 0,06464609 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02574021 0,06457868 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02574021 0,06451141 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02574021 0,06444428 ! response to UV-B GO:0010224 16 8 0,000 0,02574021 0,06437729 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02574021 0,06431044 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02574021 0,06424373 ! intermediate filament organization GO:0045109 12 8 0,000 0,02574021 0,06417716 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02574021 0,06411072 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02574021 0,06404442 ! cellular extravasation GO:0045123 12 8 0,000 0,02574021 0,06397826 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02574021 0,06391223 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02574021 0,06384635 ! response to antibiotic GO:0046677 11 8 0,000 0,02574021 0,06378059 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02574021 0,06371497 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02574021 0,06364949 ! DNA topological change GO:0006265 12 8 0,000 0,02574021 0,06358414 ! response to tropane GO:0014073 15 8 0,000 0,02574021 0,06351893 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02574021 0,06345385 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,02574021 0,0633889 ! melanosome transport GO:0032402 13 8 0,000 0,02574021 0,06332409 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,02574021 0,0632594 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02574021 0,06319485 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02574021 0,06313043 ! mast cell activation GO:0045576 14 8 0,000 0,02574021 0,06306615 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02574021 0,06300199 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02574021 0,06293796 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02574021 0,06287407 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02574021 0,0628103 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02574021 0,06274666 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02574021 0,06268315 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02574021 0,06261977 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02574021 0,06255652 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02574021 0,0624934 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02574021 0,0624304 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02574021 0,06236753 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02574021 0,06230478 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02574021 0,06224217 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02574021 0,06217967 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02574021 0,06211731 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02574021 0,06205507 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02574021 0,06199295 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02574021 0,06193096 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02574021 0,06186909 ! hormone catabolic process GO:0042447 17 8 0,000 0,02574021 0,06180734 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02574021 0,06174572 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02574021 0,06168422 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02574021 0,06162284 ! ATP catabolic process GO:0006200 11 8 0,000 0,02574021 0,06156159 ! blastocyst growth GO:0001832 19 8 0,000 0,02574021 0,06150045 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02574021 0,06143944 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02574021 0,06137855 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02574021 0,06131778 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02574021 0,06125713 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02574021 0,0611966 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02574021 0,06113619 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02574021 0,06107589 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02574021 0,06101572 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02574021 0,06095566 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02574021 0,06089573 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02574021 0,06083591 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02574021 0,06077621 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02574021 0,06071662 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02574021 0,06065716 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02574021 0,0605978 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02574021 0,06053857 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02681453 0,06300367 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,02745364 0,0644424 ! response to metal ion GO:0010038 140 80 1,000 0,02809888 0,06589269 ! T cell activation GO:0042110 168 81 1,000 0,02875019 0,0673544 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02875019 0,06728888 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,02875019 0,06722348 ! axon extension GO:0048675 15 9 0,000 0,02891127 0,06753449 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02891127 0,06746899 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02891127 0,06740361 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02891127 0,06733836 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02891127 0,06727324 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02891127 0,06720824 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02891127 0,06714337 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02891127 0,06707862 ! phosphate transport GO:0006817 19 9 0,000 0,02891127 0,067014 ! reproductive behavior GO:0019098 19 9 0,000 0,02891127 0,0669495 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02891127 0,06688512 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02891127 0,06682087 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02891127 0,06675674 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02891127 0,06669274 ! GTP metabolic process GO:0046039 9 9 0,000 0,02891127 0,06662886 ! RNA methylation GO:0001510 15 9 0,000 0,02891127 0,0665651 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02891127 0,06650146 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02891127 0,06643794 ! artery development GO:0060840 24 9 0,000 0,02891127 0,06637455 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02891127 0,06631127 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02891127 0,06624812 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02891127 0,06618509 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02891127 0,06612217 ! chemosensory behavior GO:0007635 20 9 0,000 0,02891127 0,06605938 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02891127 0,0659967 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02891127 0,06593415 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02891127 0,06587171 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02891127 0,06580939 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02891127 0,06574719 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02891127 0,06568511 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02891127 0,06562314 ! protein targeting to ER GO:0045047 22 9 0,000 0,02891127 0,06556129 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02891127 0,06549955 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02891127 0,06543794 ! T cell selection GO:0045058 23 9 0,000 0,02891127 0,06537644 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02891127 0,06531505 ! endosome organization GO:0007032 17 9 0,000 0,02891127 0,06525378 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02891127 0,06519262 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02891127 0,06513158 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02891127 0,06507065 ! mannose metabolic process GO:0006013 13 9 0,000 0,02891127 0,06500984 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02891127 0,06494914 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02891127 0,06488855 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02891127 0,06482808 ! receptor clustering GO:0043113 18 9 0,000 0,02891127 0,06476772 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02891127 0,06470747 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02891127 0,06464733 ! ruffle organization GO:0031529 15 9 0,000 0,02891127 0,0645873 ! retinol metabolic process GO:0042572 18 9 0,000 0,02891127 0,06452739 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02891127 0,06446759 ! behavioral fear response GO:0001662 22 9 0,000 0,02891127 0,0644079 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02891127 0,06434831 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02891127 0,06428884 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02891127 0,06422948 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02891127 0,06417023 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02891127 0,06411108 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02891127 0,06405205 ! segment specification GO:0007379 13 9 0,000 0,02891127 0,06399313 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02891127 0,06393431 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02891127 0,0638756 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02891127 0,063817 ! response to amine stimulus GO:0014075 13 9 0,000 0,02891127 0,0637585 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02891127 0,06370012 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02891127 0,06364184 ! erythrocyte development GO:0048821 15 9 0,000 0,02891127 0,06358366 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02891127 0,0635256 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02891127 0,06346763 ! renal water homeostasis GO:0003091 14 9 0,000 0,02891127 0,06340978 ! postreplication repair GO:0006301 22 9 0,000 0,02891127 0,06335203 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02891127 0,06329438 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02891127 0,06323684 ! icosanoid secretion GO:0032309 15 9 0,000 0,02891127 0,06317941 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02891127 0,06312208 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02891127 0,06306485 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02891127 0,06300772 ! regulation of cell division GO:0051302 15 9 0,000 0,02891127 0,0629507 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02891127 0,06289379 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02891127 0,06283697 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02891127 0,06278026 ! sterol catabolic process GO:0016127 11 9 0,000 0,02891127 0,06272365 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02891127 0,06266714 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02891127 0,06261074 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02891127 0,06255443 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02891127 0,06249823 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02891127 0,06244212 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02891127 0,06238612 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02891127 0,06233022 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02891127 0,06227442 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02891127 0,06221872 ! purine base metabolic process GO:0006144 21 9 0,000 0,02891127 0,06216312 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02891127 0,06210761 ! pigment granule transport GO:0051904 17 9 0,000 0,02891127 0,06205221 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02891127 0,0619969 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02891127 0,0619417 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02891127 0,06188659 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02891127 0,06183158 ! mitochondrion localization GO:0051646 15 9 0,000 0,02891127 0,06177667 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,03141534 0,06706771 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03207212 0,06840915 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03207212 0,06834855 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03207212 0,06828807 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03207212 0,06822769 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03207212 0,06816742 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03207212 0,06810725 ! synapsis GO:0007129 13 10 0,000 0,03207212 0,06804719 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03207212 0,06798724 ! N-glycan processing GO:0006491 20 10 0,000 0,03207212 0,06792739 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03207212 0,06786765 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03207212 0,06780801 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03207212 0,06774848 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03207212 0,06768905 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03207212 0,06762973 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03207212 0,06757051 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03207212 0,06751139 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03207212 0,06745238 ! androgen metabolic process GO:0008209 17 10 0,000 0,03207212 0,06739347 ! phospholipid efflux GO:0033700 16 10 0,000 0,03207212 0,06733466 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03207212 0,06727595 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03207212 0,06721735 ! pathogenesis GO:0009405 13 10 0,000 0,03207212 0,06715885 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03207212 0,06710045 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03207212 0,06704215 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03207212 0,06698396 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03207212 0,06692586 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03207212 0,06686787 ! endoderm development GO:0007492 16 10 0,000 0,03207212 0,06680997 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03207212 0,06675218 ! arginine catabolic process GO:0006527 13 10 0,000 0,03207212 0,06669448 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03207212 0,06663689 ! proline metabolic process GO:0006560 13 10 0,000 0,03207212 0,06657939 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03207212 0,066522 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03207212 0,0664647 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03207212 0,0664075 ! V(D)J recombination GO:0033151 28 10 0,000 0,03207212 0,0663504 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03207212 0,0662934 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03207212 0,0662365 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03207212 0,06617969 ! B cell proliferation GO:0042100 18 10 0,000 0,03207212 0,06612298 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03207212 0,06606637 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03207212 0,06600985 ! multicellular organism growth GO:0035264 18 10 0,000 0,03207212 0,06595343 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03207212 0,06589711 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03207212 0,06584089 ! epithelial cell development GO:0002064 20 10 0,000 0,03207212 0,06578476 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03207212 0,06572872 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03207212 0,06567278 ! macroautophagy GO:0016236 17 10 0,000 0,03207212 0,06561694 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03207212 0,06556119 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03207212 0,06550553 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03207212 0,06544997 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03207212 0,06539451 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03207212 0,06533913 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03207212 0,06528386 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03207212 0,06522867 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03207212 0,06517358 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03207212 0,06511858 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03207212 0,06506367 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03207212 0,06500886 ! response to dsRNA GO:0043331 20 10 0,000 0,03207212 0,06495414 ! DNA ligation GO:0006266 19 10 0,000 0,03207212 0,06489951 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03207212 0,06484497 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03207212 0,06479053 ! melanosome localization GO:0032400 16 10 0,000 0,03207212 0,06473617 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03207212 0,06468191 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03207212 0,06462774 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03207212 0,06457366 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03207212 0,06451966 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03207212 0,06446576 ! mRNA cleavage GO:0006379 17 10 0,000 0,03207212 0,06441195 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03207212 0,06435823 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03207212 0,0643046 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03207212 0,06425106 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03207212 0,0641976 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03207212 0,06414424 ! salivary gland development GO:0007431 27 10 0,000 0,03207212 0,06409096 ! prophase GO:0051324 15 10 0,000 0,03207212 0,06403777 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03207212 0,06398467 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03207212 0,06393166 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03207212 0,06387874 ! midbrain development GO:0030901 13 10 0,000 0,03207212 0,0638259 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03207212 0,06377316 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03207212 0,06372049 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03207212 0,06366792 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03207212 0,06361543 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03207212 0,06356303 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03207212 0,06351071 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03207212 0,06345849 ! detection of calcium ion GO:0005513 23 10 0,000 0,03207212 0,06340634 ! oocyte development GO:0048599 17 10 0,000 0,03207212 0,06335428 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03207212 0,06330231 ! blastocyst formation GO:0001825 17 10 0,000 0,03207212 0,06325042 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03207212 0,06319862 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03207212 0,06314691 ! activation of innate immune response GO:0002218 12 10 0,000 0,03207212 0,06309527 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03207212 0,06304372 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03207212 0,06299226 ! response to nicotine GO:0035094 20 10 0,000 0,03207212 0,06294088 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03207212 0,06288958 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03207212 0,06283837 ! localization within membrane GO:0051668 20 10 0,000 0,03207212 0,06278724 ! response to inorganic substance GO:0010035 153 86 1,000 0,03209637 0,06278364 ! regulation of protein transport GO:0051223 154 87 1,000 0,03278322 0,06407508 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,03347582 0,06537568 ! sex differentiation GO:0007548 145 90 1,000 0,03487816 0,06805909 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03522278 0,06867586 ! respiratory burst GO:0045730 17 11 0,000 0,03522278 0,06862025 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03522278 0,06856473 ! neuron fate specification GO:0048665 17 11 0,000 0,03522278 0,0685093 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03522278 0,06845396 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03522278 0,06839871 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03522278 0,06834355 ! thyroid gland development GO:0030878 26 11 0,000 0,03522278 0,06828848 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03522278 0,0682335 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03522278 0,06817861 ! response to pain GO:0048265 24 11 0,000 0,03522278 0,0681238 ! T cell proliferation GO:0042098 26 11 0,000 0,03522278 0,06806908 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03522278 0,06801445 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03522278 0,06795991 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03522278 0,06790545 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03522278 0,06785109 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03522278 0,06779681 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03522278 0,06774261 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03522278 0,0676885 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03522278 0,06763448 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03522278 0,06758055 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03522278 0,0675267 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03522278 0,06747294 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03522278 0,06741926 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03522278 0,06736567 ! UV protection GO:0009650 19 11 0,000 0,03522278 0,06731216 ! adult heart development GO:0007512 14 11 0,000 0,03522278 0,06725874 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03522278 0,0672054 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03522278 0,06715214 ! temperature homeostasis GO:0001659 17 11 0,000 0,03522278 0,06709898 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03522278 0,06704589 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03522278 0,06699289 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03522278 0,06693997 ! regulation of organ growth GO:0046620 13 11 0,000 0,03522278 0,06688714 ! pigment granule localization GO:0051875 20 11 0,000 0,03522278 0,06683439 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03522278 0,06678172 ! vasoconstriction GO:0042310 18 11 0,000 0,03522278 0,06672914 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03522278 0,06667664 ! embryonic axis specification GO:0000578 18 11 0,000 0,03522278 0,06662422 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03522278 0,06657188 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03522278 0,06651963 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03522278 0,06646746 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03522278 0,06641537 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03522278 0,06636336 ! zymogen activation GO:0031638 15 11 0,000 0,03522278 0,06631143 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03522278 0,06625958 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03522278 0,06620782 ! nucleosome positioning GO:0016584 15 11 0,000 0,03522278 0,06615613 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03522278 0,06610453 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03522278 0,06605301 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03522278 0,06600156 ! acid secretion GO:0046717 18 11 0,000 0,03522278 0,0659502 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03522278 0,06589892 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03522278 0,06584771 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03522278 0,06579659 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03522278 0,06574554 ! oocyte differentiation GO:0009994 18 11 0,000 0,03522278 0,06569458 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03522278 0,06564369 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03522278 0,06559288 ! cholesterol efflux GO:0033344 19 11 0,000 0,03522278 0,06554216 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03522278 0,0654915 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03522278 0,06544093 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03522278 0,06539044 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03522278 0,06534002 ! embryonic gut development GO:0048566 15 11 0,000 0,03522278 0,06528968 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03522278 0,06523942 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03522278 0,06518924 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03522278 0,06513913 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03522278 0,0650891 ! defense response to fungus GO:0050832 13 11 0,000 0,03522278 0,06503915 ! developmental induction GO:0031128 19 11 0,000 0,03522278 0,06498927 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03522278 0,06493947 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03522278 0,06488974 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03522278 0,0648401 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03522278 0,06479053 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03522278 0,06474103 ! nucleus localization GO:0051647 19 11 0,000 0,03522278 0,06469161 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03522278 0,06464226 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,03702381 0,0678958 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03702381 0,06784409 ! transcription initiation GO:0006352 153 94 1,000 0,0377501 0,06912233 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03836329 0,07019169 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03836329 0,07013835 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03836329 0,0700851 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03836329 0,07003192 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03836329 0,06997883 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03836329 0,06992581 ! cartilage condensation GO:0001502 20 12 0,000 0,03836329 0,06987288 ! mating GO:0007618 17 12 0,000 0,03836329 0,06982002 ! protein complex disassembly GO:0043241 27 12 0,000 0,03836329 0,06976725 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03836329 0,06971456 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03836329 0,06966194 ! hippocampus development GO:0021766 26 12 0,000 0,03836329 0,06960941 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03836329 0,06955695 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03836329 0,06950457 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03836329 0,06945227 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03836329 0,06940005 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03836329 0,06934791 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03836329 0,06929585 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03836329 0,06924386 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03836329 0,06919196 ! drug transport GO:0015893 16 12 0,000 0,03836329 0,06914013 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03836329 0,06908838 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03836329 0,0690367 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03836329 0,06898511 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03836329 0,06893359 ! focal adhesion formation GO:0048041 35 12 0,000 0,03836329 0,06888214 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03836329 0,06883078 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03836329 0,06877949 ! forebrain cell migration GO:0021885 21 12 0,000 0,03836329 0,06872827 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03836329 0,06867714 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03836329 0,06862608 ! entry into host cell GO:0030260 32 12 0,000 0,03836329 0,06857509 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03836329 0,06852418 ! monoamine transport GO:0015844 18 12 0,000 0,03836329 0,06847335 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03836329 0,06842259 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03836329 0,06837191 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03836329 0,0683213 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03836329 0,06827076 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03836329 0,0682203 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03836329 0,06816992 ! protein homotetramerization GO:0051289 21 12 0,000 0,03836329 0,06811961 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03836329 0,06806937 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03836329 0,06801921 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03836329 0,06796913 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03836329 0,06791911 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03836329 0,06786917 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03836329 0,0678193 ! cranial nerve development GO:0021545 20 12 0,000 0,03836329 0,06776951 ! fucose catabolic process GO:0019317 22 12 0,000 0,03836329 0,06771979 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03836329 0,06767014 ! histone methylation GO:0016571 26 12 0,000 0,03836329 0,06762057 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03836329 0,06757106 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03836329 0,06752163 ! gland morphogenesis GO:0022612 29 12 0,000 0,03836329 0,06747227 ! T cell homeostasis GO:0043029 25 12 0,000 0,03836329 0,06742299 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03836329 0,06737378 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03836329 0,06732463 ! spleen development GO:0048536 22 12 0,000 0,03836329 0,06727556 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03836329 0,06722656 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03836329 0,06717764 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03836329 0,06712878 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03836329 0,06707999 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03836329 0,06703128 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03836329 0,06698264 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03836329 0,06693406 ! response to cold GO:0009409 17 12 0,000 0,03836329 0,06688556 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03836329 0,06683713 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03836329 0,06678876 ! mRNA transport GO:0051028 169 96 1,000 0,03921901 0,06822917 ! detection of stimulus GO:0051606 151 96 1,000 0,03921901 0,06817987 ! regulation of protein localization GO:0032880 176 97 1,000 0,03996156 0,06942058 ! response to virus GO:0009615 160 98 1,000 0,04070944 0,07066876 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,04146261 0,07192432 GO:0060538|skeletal muscle organ development, ! cGMP metabolic process GO:0046068 18 13 0,000 0,04149368 0,07192636 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04149368 0,07187458 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04149368 0,07182287 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04149368 0,07177124 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04149368 0,07171968 ! lipid localization GO:0010876 28 13 0,000 0,04149368 0,07166819 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04149368 0,07161678 ! organelle fusion GO:0048284 32 13 0,000 0,04149368 0,07156544 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04149368 0,07151418 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04149368 0,07146299 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04149368 0,07141187 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04149368 0,07136082 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04149368 0,07130985 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04149368 0,07125895 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04149368 0,07120812 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04149368 0,07115737 ! methionine metabolic process GO:0006555 27 13 0,000 0,04149368 0,07110669 ! plasma membrane organization GO:0007009 24 13 0,000 0,04149368 0,07105608 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04149368 0,07100554 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04149368 0,07095508 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04149368 0,07090468 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04149368 0,07085436 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04149368 0,07080411 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,04149368 0,07075393 ! exocrine system development GO:0035272 32 13 0,000 0,04149368 0,07070382 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04149368 0,07065378 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04149368 0,07060381 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04149368 0,07055392 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04149368 0,07050409 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04149368 0,07045433 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04149368 0,07040465 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04149368 0,07035503 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04149368 0,07030549 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04149368 0,07025601 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04149368 0,0702066 ! ribosome assembly GO:0042255 17 13 0,000 0,04149368 0,07015727 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04149368 0,070108 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04149368 0,0700588 ! chromatin silencing GO:0006342 26 13 0,000 0,04149368 0,07000967 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04149368 0,06996061 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04149368 0,06991162 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04149368 0,06986269 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04149368 0,06981384 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04149368 0,06976505 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04149368 0,06971633 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04149368 0,06966768 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04149368 0,0696191 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04149368 0,06957059 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04149368 0,06952214 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04149368 0,06947376 ! insulin secretion GO:0030073 23 13 0,000 0,04149368 0,06942545 ! actin filament polymerization GO:0030041 24 13 0,000 0,04149368 0,0693772 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04149368 0,06932902 ! acrosome reaction GO:0007340 18 13 0,000 0,04149368 0,06928091 ! rRNA transcription GO:0009303 25 14 0,000 0,04461398 0,07443914 ! lactation GO:0007595 26 14 0,000 0,04461398 0,07438755 ! reproductive cellular process GO:0048610 20 14 0,000 0,04461398 0,07433604 ! tRNA modification GO:0006400 20 14 0,000 0,04461398 0,0742846 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04461398 0,07423322 ! regulation of S phase GO:0033261 23 14 0,000 0,04461398 0,07418192 ! water transport GO:0006833 21 14 0,000 0,04461398 0,07413069 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04461398 0,07407953 ! non-recombinational repair GO:0000726 25 14 0,000 0,04461398 0,07402844 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04461398 0,07397742 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04461398 0,07392647 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04461398 0,0738756 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04461398 0,07382479 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04461398 0,07377405 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04461398 0,07372338 ! palate development GO:0060021 31 14 0,000 0,04461398 0,07367278 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04461398 0,07362225 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04461398 0,07357179 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04461398 0,0735214 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04461398 0,07347108 ! arginine metabolic process GO:0006525 17 14 0,000 0,04461398 0,07342082 ! regulation of heart rate GO:0002027 24 14 0,000 0,04461398 0,07337064 ! organic alcohol transport GO:0015850 29 14 0,000 0,04461398 0,07332052 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04461398 0,07327047 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04461398 0,07322049 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04461398 0,07317058 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04461398 0,07312074 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04461398 0,07307096 ! L-amino acid transport GO:0015807 30 14 0,000 0,04461398 0,07302125 ! bone mineralization GO:0030282 17 14 0,000 0,04461398 0,07297161 ! stem cell development GO:0048864 43 14 0,000 0,04461398 0,07292204 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04461398 0,07287253 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04461398 0,07282309 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04461398 0,07277372 ! cerebellum development GO:0021549 21 14 0,000 0,04461398 0,07272442 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04461398 0,07267518 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04461398 0,07262601 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04461398 0,0725769 ! cofactor transport GO:0051181 26 14 0,000 0,04461398 0,07252787 ! NADP metabolic process GO:0006739 24 14 0,000 0,04461398 0,07247889 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04461398 0,07242999 ! intestinal absorption GO:0050892 25 14 0,000 0,04461398 0,07238115 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04461398 0,07233237 ! oxygen transport GO:0015671 21 14 0,000 0,04461398 0,07228366 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04461398 0,07223502 ! regulation of axon extension GO:0030516 37 14 0,000 0,04461398 0,07218644 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04461398 0,07213793 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04772423 0,07711518 ! positive regulation of cell size GO:0045793 27 15 0,000 0,04772423 0,07706342 ! superoxide anion generation GO:0042554 20 15 0,000 0,04772423 0,07701174 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04772423 0,07696012 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04772423 0,07690857 ! copper ion transport GO:0006825 20 15 0,000 0,04772423 0,0768571 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04772423 0,07680569 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04772423 0,07675435 ! sulfate transport GO:0008272 23 15 0,000 0,04772423 0,07670307 ! response to cAMP GO:0051591 22 15 0,000 0,04772423 0,07665187 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04772423 0,07660073 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04772423 0,07654967 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04772423 0,07649867 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04772423 0,07644774 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04772423 0,07639687 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04772423 0,07634608 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04772423 0,07629535 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04772423 0,07624469 ! pituitary gland development GO:0021983 29 15 0,000 0,04772423 0,07619409 ! vesicle coating GO:0006901 33 15 0,000 0,04772423 0,07614357 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04772423 0,07609311 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04772423 0,07604272 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04772423 0,07599239 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04772423 0,07594213 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04772423 0,07589194 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04772423 0,07584181 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04772423 0,07579175 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04772423 0,07574175 ! histone deacetylation GO:0016575 20 15 0,000 0,04772423 0,07569183 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04772423 0,07564196 ! tissue regeneration GO:0042246 26 15 0,000 0,04772423 0,07559217 ! water homeostasis GO:0030104 27 15 0,000 0,04772423 0,07554243 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04772423 0,07549277 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04772423 0,07544317 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04772423 0,07539363 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04772423 0,07534416 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04772423 0,07529475 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04772423 0,07524541 ! cell killing GO:0001906 29 15 0,000 0,04772423 0,07519614 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04772423 0,07514692 ! detection of bacterium GO:0016045 18 15 0,000 0,04772423 0,07509778 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04772423 0,07504869 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04772423 0,07499967 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04772423 0,07495072 ! peptide hormone processing GO:0016486 23 15 0,000 0,04772423 0,07490183 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05082446 0,07971555 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05082446 0,07966361 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05082446 0,07961175 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05082446 0,07955995 ! bone remodeling GO:0046849 27 16 0,000 0,05082446 0,07950822 ! filopodium assembly GO:0046847 32 16 0,000 0,05082446 0,07945656 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05082446 0,07940497 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05082446 0,07935344 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05082446 0,07930198 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05082446 0,07925058 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05082446 0,07919925 ! startle response GO:0001964 28 16 0,000 0,05082446 0,07914799 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05082446 0,0790968 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05082446 0,07904567 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05082446 0,0789946 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05082446 0,07894361 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05082446 0,07889267 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05082446 0,07884181 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05082446 0,07879101 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05082446 0,07874027 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05082446 0,0786896 ! response to osmotic stress GO:0006970 25 16 0,000 0,05082446 0,078639 ! lysosomal transport GO:0007041 26 16 0,000 0,05082446 0,07858846 ! fructose metabolic process GO:0006000 25 16 0,000 0,05082446 0,07853799 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05082446 0,07848758 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05082446 0,07843723 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05082446 0,07838695 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,05082446 0,07833674 ! negative regulation of immune response GO:0050777 35 16 0,000 0,05082446 0,07828659 ! axon cargo transport GO:0008088 43 16 0,000 0,05082446 0,0782365 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05082446 0,07818647 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05082446 0,07813652 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,05082446 0,07808662 ! DNA replication initiation GO:0006270 27 16 0,000 0,05082446 0,07803679 ! neuron recognition GO:0008038 35 16 0,000 0,05082446 0,07798702 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05082446 0,07793731 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05082446 0,07788767 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05082446 0,07783809 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05082446 0,07778858 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05082446 0,07773913 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05082446 0,07768974 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05082446 0,07764041 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05082446 0,07759115 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05082446 0,07754194 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05082446 0,0774928 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05082446 0,07744373 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,05082446 0,07739471 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05391469 0,08204855 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05391469 0,08199668 ! metencephalon development GO:0022037 30 17 0,000 0,05391469 0,08194489 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05391469 0,08189315 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05391469 0,08184149 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05391469 0,08178988 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05391469 0,08173835 ! signal complex assembly GO:0007172 41 17 0,000 0,05391469 0,08168687 ! endothelial cell migration GO:0043542 28 17 0,000 0,05391469 0,08163547 ! inositol metabolic process GO:0006020 28 17 0,000 0,05391469 0,08158412 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05391469 0,08153284 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05391469 0,08148163 ! glial cell development GO:0021782 27 17 0,000 0,05391469 0,08143048 ! limbic system development GO:0021761 36 17 0,000 0,05391469 0,08137939 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05391469 0,08132837 ! adult walking behavior GO:0007628 33 17 0,000 0,05391469 0,08127742 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05391469 0,08122652 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05391469 0,08117569 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05391469 0,08112492 ! myoblast differentiation GO:0045445 45 17 0,000 0,05391469 0,08107422 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05391469 0,08102358 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05391469 0,08097301 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05391469 0,08092249 ! glycine metabolic process GO:0006544 28 17 0,000 0,05391469 0,08087204 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05391469 0,08082165 ! NAD metabolic process GO:0019674 29 17 0,000 0,05391469 0,08077133 ! membrane budding GO:0006900 37 17 0,000 0,05391469 0,08072107 ! DNA integration GO:0015074 29 17 0,000 0,05391469 0,08067087 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05391469 0,08062073 ! regulation of protein binding GO:0043393 33 17 0,000 0,05391469 0,08057066 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05391469 0,08052064 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05391469 0,08047069 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05391469 0,0804208 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05391469 0,08037098 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05391469 0,08032121 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05391469 0,08027151 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05391469 0,08022186 ! steroid catabolic process GO:0006706 31 17 0,000 0,05391469 0,08017228 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05391469 0,08012276 ! gas transport GO:0015669 25 17 0,000 0,05391469 0,08007331 ! organic cation transport GO:0015695 31 17 0,000 0,05391469 0,08002391 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05391469 0,07997457 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05391469 0,0799253 ! microspike assembly GO:0030035 36 17 0,000 0,05391469 0,07987608 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05391469 0,07982693 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05699497 0,08433573 ! neuron maturation GO:0042551 42 18 0,000 0,05699497 0,0842839 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05699497 0,08423213 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05699497 0,08418042 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,05699497 0,08412877 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05699497 0,08407719 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05699497 0,08402568 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05699497 0,08397422 ! memory GO:0007613 31 18 0,000 0,05699497 0,08392283 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05699497 0,0838715 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05699497 0,08382023 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05699497 0,08376903 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05699497 0,08371789 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05699497 0,08366681 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05699497 0,08361579 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05699497 0,08356484 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05699497 0,08351395 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05699497 0,08346312 ! response to fungus GO:0009620 21 18 0,000 0,05699497 0,08341235 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05699497 0,08336164 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05699497 0,083311 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05699497 0,08326041 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05699497 0,08320989 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05699497 0,08315943 ! vitamin transport GO:0051180 27 18 0,000 0,05699497 0,08310903 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05699497 0,08305869 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05699497 0,08300842 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05699497 0,0829582 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05699497 0,08290804 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05699497 0,08285795 ! nerve development GO:0021675 28 18 0,000 0,05699497 0,08280791 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05699497 0,08275794 ! protein secretion GO:0009306 39 19 0,000 0,06006532 0,08716355 ! positive regulation of translation GO:0045727 30 19 0,000 0,06006532 0,08711101 ! negative regulation of defense response GO:0031348 25 19 0,000 0,06006532 0,08705853 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,06006532 0,08700612 ! skin development GO:0043588 36 19 0,000 0,06006532 0,08695377 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,06006532 0,08690148 ! lipid phosphorylation GO:0046834 35 19 0,000 0,06006532 0,08684926 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06006532 0,0867971 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,06006532 0,086745 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,06006532 0,08669296 ! bile acid metabolic process GO:0008206 29 19 0,000 0,06006532 0,08664099 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,06006532 0,08658908 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,06006532 0,08653723 ! cerebral cortex development GO:0021987 36 19 0,000 0,06006532 0,08648544 ! pigmentation during development GO:0048066 41 19 0,000 0,06006532 0,08643371 ! heme metabolic process GO:0042168 36 19 0,000 0,06006532 0,08638205 ! actin filament bundle formation GO:0051017 42 19 0,000 0,06006532 0,08633045 ! neuromuscular junction development GO:0007528 34 19 0,000 0,06006532 0,08627891 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,06006532 0,08622743 ! peptide cross-linking GO:0018149 37 19 0,000 0,06006532 0,08617601 ! protein export from nucleus GO:0006611 36 19 0,000 0,06006532 0,08612465 ! heart process GO:0003015 30 19 0,000 0,06006532 0,08607336 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,06006532 0,08602212 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,06006532 0,08597095 ! visual learning GO:0008542 36 19 0,000 0,06006532 0,08591984 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,06006532 0,08586879 ! cell-cell junction organization GO:0045216 35 19 0,000 0,06006532 0,0858178 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,06006532 0,08576686 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,06006532 0,08571599 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,06006532 0,08566519 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,06006532 0,08561444 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,06006532 0,08556375 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,06006532 0,08551312 ! cilium assembly GO:0042384 37 19 0,000 0,06006532 0,08546255 ! peptide hormone secretion GO:0030072 31 19 0,000 0,06006532 0,08541204 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06312578 0,08971094 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06312578 0,08965798 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06312578 0,08960509 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06312578 0,08955225 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06312578 0,08949948 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06312578 0,08944677 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06312578 0,08939413 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06312578 0,08934154 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06312578 0,08928902 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06312578 0,08923656 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06312578 0,08918416 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06312578 0,08913182 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06312578 0,08907954 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06312578 0,08902733 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06312578 0,08897518 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06312578 0,08892308 ! body fluid secretion GO:0007589 31 20 0,000 0,06312578 0,08887105 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06312578 0,08881908 ! peptide secretion GO:0002790 35 20 0,000 0,06312578 0,08876717 ! stem cell differentiation GO:0048863 53 20 0,000 0,06312578 0,08871532 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06312578 0,08866353 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06312578 0,0886118 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06312578 0,08856013 ! sensory perception of pain GO:0019233 30 20 0,000 0,06312578 0,08850852 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06312578 0,08845697 ! diencephalon development GO:0021536 34 20 0,000 0,06312578 0,08840549 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06312578 0,08835406 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06312578 0,08830269 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06312578 0,08825138 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06312578 0,08820013 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06312578 0,08814894 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06312578 0,08809781 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06312578 0,08804674 ! regulation of glucose import GO:0046324 29 20 0,000 0,06312578 0,08799573 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06312578 0,08794477 ! actin filament-based movement GO:0030048 43 20 0,000 0,06312578 0,08789388 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06312578 0,08784304 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,06312578 0,08779227 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06312578 0,08774155 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06312578 0,08769089 ! regulation of cell killing GO:0031341 42 21 0,000 0,06617637 0,09187556 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06617637 0,09182258 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06617637 0,09176965 ! hormone secretion GO:0046879 38 21 0,000 0,06617637 0,09171679 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06617637 0,09166399 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06617637 0,09161125 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06617637 0,09155857 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06617637 0,09150595 ! axis specification GO:0009798 38 21 0,000 0,06617637 0,09145339 ! ovarian follicle development GO:0001541 35 21 0,000 0,06617637 0,09140089 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06617637 0,09134845 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06617637 0,09129607 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06617637 0,09124375 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06617637 0,09119149 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06617637 0,0911393 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06617637 0,09108716 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06617637 0,09103508 ! cytolysis GO:0019835 24 21 0,000 0,06617637 0,09098306 ! vasodilation GO:0042311 39 21 0,000 0,06617637 0,0909311 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06617637 0,09087919 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06617637 0,09082735 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06617637 0,09077557 ! oogenesis GO:0048477 36 21 0,000 0,06617637 0,09072385 ! collagen fibril organization GO:0030199 59 21 0,000 0,06617637 0,09067218 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06617637 0,09062057 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06617637 0,09056903 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06617637 0,09051754 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06617637 0,09046611 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06617637 0,09041474 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06617637 0,09036342 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06617637 0,09031217 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06617637 0,09026097 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06617637 0,09020983 ! collagen catabolic process GO:0030574 28 21 0,000 0,06617637 0,09015875 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06617637 0,09010772 ! gut development GO:0048565 39 21 0,000 0,06617637 0,09005676 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06921713 0,09414156 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06921713 0,09408837 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06921713 0,09403524 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06921713 0,09398218 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06921713 0,09392917 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06921713 0,09387622 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06921713 0,09382333 ! regeneration GO:0031099 41 22 0,000 0,06921713 0,09377051 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06921713 0,09371774 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06921713 0,09366503 ! sensory perception of taste GO:0050909 28 22 0,000 0,06921713 0,09361238 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,06921713 0,09355979 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06921713 0,09350725 ! vacuolar transport GO:0007034 36 22 0,000 0,06921713 0,09345478 ! lysosome organization GO:0007040 41 22 0,000 0,06921713 0,09340237 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06921713 0,09335001 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06921713 0,09329771 ! fucose metabolic process GO:0006004 39 22 0,000 0,06921713 0,09324547 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06921713 0,09319329 ! ureteric bud development GO:0001657 43 22 0,000 0,06921713 0,09314117 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06921713 0,09308911 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06921713 0,0930371 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06921713 0,09298516 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06921713 0,09293327 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06921713 0,09288144 ! sarcomere organization GO:0045214 30 22 0,000 0,06921713 0,09282966 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,06921713 0,09277795 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06921713 0,09272629 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06921713 0,09267469 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06921713 0,09262315 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06921713 0,09257166 ! protein stabilization GO:0050821 39 22 0,000 0,06921713 0,09252023 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,07224809 0,09651799 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07224809 0,09646443 ! gluconeogenesis GO:0006094 33 23 0,000 0,07224809 0,09641093 ! viral genome replication GO:0019079 41 23 0,000 0,07224809 0,09635749 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07224809 0,0963041 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07224809 0,09625078 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07224809 0,09619751 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07224809 0,09614431 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07224809 0,09609116 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07224809 0,09603807 ! visual behavior GO:0007632 42 23 0,000 0,07224809 0,09598504 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,07224809 0,09593207 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07224809 0,09587915 ! response to ethanol GO:0045471 46 23 0,000 0,07224809 0,0958263 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07224809 0,0957735 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,07224809 0,09572076 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07224809 0,09566808 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07224809 0,09561546 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07224809 0,09556289 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07224809 0,09551039 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07224809 0,09545794 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07224809 0,09540555 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07224809 0,09535321 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07224809 0,09530094 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07224809 0,09524872 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07224809 0,09519655 ! fatty acid transport GO:0015908 44 23 0,000 0,07224809 0,09514445 ! platelet activation GO:0030168 37 23 0,000 0,07224809 0,0950924 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07224809 0,09504041 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07224809 0,09498847 ! hormone transport GO:0009914 40 23 0,000 0,07224809 0,0949366 ! cell-cell recognition GO:0009988 25 23 0,000 0,07224809 0,09488477 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07224809 0,09483301 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07224809 0,0947813 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07224809 0,09472965 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07224809 0,09467805 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07224809 0,09462651 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07526928 0,09852986 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07526928 0,09847629 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07526928 0,09842277 ! vesicle docking GO:0048278 47 24 0,000 0,07526928 0,0983693 ! spinal cord development GO:0021510 47 24 0,000 0,07526928 0,0983159 ! vacuole organization GO:0007033 43 24 0,000 0,07526928 0,09826255 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07526928 0,09820927 ! digestive system process GO:0022600 39 24 0,000 0,07526928 0,09815604 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07526928 0,09810286 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07526928 0,09804975 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07526928 0,09799669 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07526928 0,09794369 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07526928 0,09789075 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,07526928 0,09783787 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07526928 0,09778504 ! membrane depolarization GO:0051899 39 24 0,000 0,07526928 0,09773227 ! pallium development GO:0021543 49 24 0,000 0,07526928 0,09767955 ! pentose metabolic process GO:0019321 35 24 0,000 0,07526928 0,09762689 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07526928 0,09757429 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07526928 0,09752175 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07526928 0,09746926 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07526928 0,09741683 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07526928 0,09736446 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07526928 0,09731214 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07526928 0,09725988 ! regulation of amine transport GO:0051952 40 24 0,000 0,07526928 0,09720767 ! myelination GO:0042552 45 25 0,000 0,07828073 0,10104262 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07828073 0,10098844 ! phototransduction GO:0007602 33 25 0,000 0,07828073 0,10093432 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07828073 0,10088026 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,07828073 0,10082625 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07828073 0,10077231 ! receptor metabolic process GO:0043112 46 25 0,000 0,07828073 0,10071842 ! chromosome condensation GO:0030261 45 25 0,000 0,07828073 0,10066459 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07828073 0,10061081 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07828073 0,1005571 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07828073 0,10050344 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07828073 0,10044984 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07828073 0,10039629 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07828073 0,1003428 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07828073 0,10028937 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07828073 0,100236 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07828073 0,10018268 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07828073 0,10012942 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07828073 0,10007622 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07828073 0,10002307 ! telomere organization GO:0032200 43 25 0,000 0,07828073 0,09996998 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07828073 0,09991694 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07828073 0,09986397 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08128248 0,10363839 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08128248 0,10358349 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08128248 0,10352866 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08128248 0,10347388 ! initiation of viral infection GO:0019059 57 26 0,000 0,08128248 0,10341916 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08128248 0,1033645 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08128248 0,1033099 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08128248 0,10325535 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08128248 0,10320086 ! molting cycle process GO:0022404 50 26 0,000 0,08128248 0,10314643 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,08128248 0,10309206 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08128248 0,10303774 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,08128248 0,10298348 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,08128248 0,10292928 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,08128248 0,10287514 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,08128248 0,10282105 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08128248 0,10276702 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08128248 0,10271304 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08128248 0,10265913 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,08128248 0,10260527 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08128248 0,10255146 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,08128248 0,10249771 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08128248 0,10244402 ! blastocyst development GO:0001824 49 26 0,000 0,08128248 0,10239039 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08128248 0,10233681 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08128248 0,10228328 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,08128248 0,10222982 ! neuron fate commitment GO:0048663 48 27 0,000 0,08427454 0,10593759 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,08427454 0,10588227 ! iron ion transport GO:0006826 59 27 0,000 0,08427454 0,10582701 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,08427454 0,10577181 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08427454 0,10571666 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08427454 0,10566157 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08427454 0,10560654 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08427454 0,10555156 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08427454 0,10549665 ! autophagy GO:0006914 41 27 0,000 0,08427454 0,10544179 ! male gonad development GO:0008584 44 27 0,000 0,08427454 0,10538698 ! response to toxin GO:0009636 47 27 0,000 0,08427454 0,10533224 ! primary neural tube formation GO:0014020 51 27 0,000 0,08427454 0,10527755 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08427454 0,10522291 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08427454 0,10516834 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08427454 0,10511382 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08427454 0,10505935 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08427454 0,10500495 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08427454 0,1049506 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,08427454 0,1048963 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08725697 0,10855236 ! circadian rhythm GO:0007623 50 28 0,000 0,08725697 0,10849626 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08725697 0,10844022 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08725697 0,10838423 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08725697 0,10832831 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08725697 0,10827244 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08725697 0,10821663 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08725697 0,10816088 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08725697 0,10810518 ! synaptogenesis GO:0007416 42 28 0,000 0,08725697 0,10804954 ! lipid oxidation GO:0034440 43 28 0,000 0,08725697 0,10799396 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08725697 0,10793844 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08725697 0,10788297 ! translational initiation GO:0006413 65 29 0,000 0,09022977 0,1115012 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,09022977 0,11144396 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,09022977 0,11138678 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,09022977 0,11132966 ! catechol metabolic process GO:0009712 54 29 0,000 0,09022977 0,1112726 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,09022977 0,11121559 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,09022977 0,11115865 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,09022977 0,11110176 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,09022977 0,11104493 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,09022977 0,11098816 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,09022977 0,11093144 ! cell fate determination GO:0001709 60 29 0,000 0,09022977 0,11087479 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,09022977 0,11081819 ! detection of light stimulus GO:0009583 38 29 0,000 0,09022977 0,11076165 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,09022977 0,11070517 ! tissue homeostasis GO:0001894 48 29 0,000 0,09022977 0,11064874 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,09022977 0,11059238 ! phenol metabolic process GO:0018958 55 30 0,000 0,093193 0,11416617 ! zinc ion transport GO:0006829 45 30 0,000 0,093193 0,11410807 ! membrane docking GO:0022406 61 30 0,000 0,093193 0,11405003 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,093193 0,11399205 ! cell junction assembly GO:0034329 78 30 0,000 0,093193 0,11393412 ! regulation of innate immune response GO:0045088 51 30 0,000 0,093193 0,11387626 ! acute-phase response GO:0006953 49 30 0,000 0,093193 0,11381845 ! myofibril assembly GO:0030239 47 30 0,000 0,093193 0,11376071 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,093193 0,11370302 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,093193 0,11364539 ! phospholipid transport GO:0015914 51 30 0,000 0,093193 0,11358782 ! ensheathment of neurons GO:0007272 57 30 0,000 0,093193 0,11353031 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,093193 0,11347285 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,093193 0,11341545 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,093193 0,11335812 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,093193 0,11330084 ! eye morphogenesis GO:0048592 60 30 0,000 0,093193 0,11324361 ! regulation of B cell activation GO:0050864 50 30 0,000 0,093193 0,11318645 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09614667 0,11671488 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09614667 0,11665602 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09614667 0,11659722 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09614667 0,11653848 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09614667 0,1164798 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09614667 0,11642118 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09614667 0,11636262 ! ovulation cycle process GO:0022602 49 31 0,000 0,09614667 0,11630412 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09614667 0,11624567 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09614667 0,11618729 ! peptide transport GO:0015833 55 31 0,000 0,09614667 0,11612896 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09614667 0,11607069 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09614667 0,11601248 ! mesoderm formation GO:0001707 69 31 0,000 0,09614667 0,11595433 ! natural killer cell activation GO:0030101 45 31 0,000 0,09614667 0,11589624 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09614667 0,1158382 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09614667 0,11578022 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09614667 0,1157223 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09614667 0,11566444 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09614667 0,11560664 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09909082 0,11908717 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09909082 0,11902771 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09909082 0,11896832 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09909082 0,11890898 ! cholesterol transport GO:0030301 56 32 0,000 0,09909082 0,1188497 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09909082 0,11879049 ! spliceosome assembly GO:0000245 67 32 0,000 0,09909082 0,11873133 ! spindle organization GO:0007051 46 32 0,000 0,09909082 0,11867223 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09909082 0,11861319 ! metanephros development GO:0001656 74 32 0,000 0,09909082 0,1185542 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09909082 0,11849528 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09909082 0,11843642 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,09909082 0,11837761 ! muscle cell development GO:0055001 49 32 0,000 0,09909082 0,11831886 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09909082 0,11826017 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09909082 0,11820154 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09909082 0,11814297 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09909082 0,11808445 ! ovulation cycle GO:0042698 51 32 0,000 0,09909082 0,11802599 ! peripheral nervous system development GO:0007422 64 32 0,000 0,09909082 0,11796759 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09909082 0,11790925 ! hindbrain development GO:0030902 61 32 0,000 0,09909082 0,11785097 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09909082 0,11779274 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09909082 0,11773457 ! gene silencing GO:0016458 65 32 0,000 0,09909082 0,11767646 ! post-embryonic development GO:0009791 69 33 0,000 0,10202547 0,12110177 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10202547 0,12104205 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10202547 0,1209824 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10202547 0,1209228 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10202547 0,12086326 ! cell fate specification GO:0001708 52 33 0,000 0,10202547 0,12080378 ! sterol transport GO:0015918 57 33 0,000 0,10202547 0,12074436 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10202547 0,120685 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10202547 0,12062569 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10202547 0,12056645 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,10202547 0,12050726 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10202547 0,12044813 ! glial cell differentiation GO:0010001 63 34 0,000 0,10495066 0,12384075 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10495066 0,12378005 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10495066 0,1237194 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10495066 0,12365881 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10495066 0,12359829 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10495066 0,12353782 ! mismatch repair GO:0006298 46 34 0,000 0,10495066 0,12347741 ! spermatid development GO:0007286 63 34 0,000 0,10495066 0,12341706 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10495066 0,12335677 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10495066 0,12329653 ! regulation of muscle development GO:0048634 70 35 0,000 0,10786643 0,12666014 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10786643 0,12659835 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10786643 0,12653663 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10786643 0,12647496 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10786643 0,12641336 ! female gonad development GO:0008585 58 35 0,000 0,10786643 0,12635181 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10786643 0,12629033 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10786643 0,1262289 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,10786643 0,12616754 ! cytokine production GO:0001816 59 35 0,000 0,10786643 0,12610623 ! neural tube formation GO:0001841 67 35 0,000 0,10786643 0,12604498 ! vesicle localization GO:0051648 64 35 0,000 0,10786643 0,1259838 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,11077278 0,12931554 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,11077278 0,12925282 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,11077278 0,12919017 ! cell junction organization GO:0034330 86 36 0,000 0,11077278 0,12912758 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,11077278 0,12906505 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,11077278 0,12900257 ! positive regulation of cell development GO:0010720 80 36 0,000 0,11077278 0,12894016 ! regulation of proteolysis GO:0030162 72 36 0,000 0,11077278 0,12887781 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,11077278 0,12881552 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,11077278 0,12875329 ! aerobic respiration GO:0009060 55 36 0,000 0,11077278 0,12869112 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,11077278 0,12862902 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,11077278 0,12856697 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,11077278 0,12850498 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11366977 0,13180215 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11366977 0,13173867 ! meiosis I GO:0007127 65 37 0,000 0,11366977 0,13167524 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11366977 0,13161187 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11366977 0,13154857 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11366977 0,13148532 ! organic anion transport GO:0015711 68 37 0,000 0,11366977 0,13142214 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,11366977 0,13135902 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11366977 0,13129595 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11366977 0,13123295 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11366977 0,13117001 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,11366977 0,13110713 ! pigment metabolic process GO:0042440 80 37 0,000 0,11366977 0,13104431 ! spermatid differentiation GO:0048515 66 37 0,000 0,11366977 0,13098155 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11655742 0,13424468 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11655742 0,13418045 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11655742 0,13411628 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11655742 0,13405217 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11655742 0,13398812 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,11655742 0,13392414 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11655742 0,13386021 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11655742 0,13379635 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11655742 0,13373254 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11655742 0,1336688 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,11655742 0,13360512 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11655742 0,1335415 ! mRNA catabolic process GO:0006402 71 39 0,000 0,11943575 0,13677411 ! mammary gland development GO:0030879 86 39 0,000 0,11943575 0,13670905 ! learning GO:0007612 77 39 0,000 0,11943575 0,13664404 ! organic ether metabolic process GO:0018904 55 39 0,000 0,11943575 0,13657909 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11943575 0,13651421 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11943575 0,13644939 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,11943575 0,13638463 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11943575 0,13631993 ! RNA modification GO:0009451 57 39 0,000 0,11943575 0,13625529 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11943575 0,13619072 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,1223048 0,13939619 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,1223048 0,13933018 ! feeding behavior GO:0007631 59 40 0,000 0,1223048 0,13926424 ! negative regulation of binding GO:0051100 72 40 0,000 0,1223048 0,13919837 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,1223048 0,13913255 ! maintenance of protein location GO:0045185 91 40 0,000 0,1223048 0,1390668 ! cytokinesis GO:0000910 72 40 0,000 0,1223048 0,13900111 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1251646 0,14218415 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1251646 0,14211705 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1251646 0,14205001 ! gliogenesis GO:0042063 88 41 0,000 0,1251646 0,14198304 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1251646 0,14191613 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,1251646 0,14184928 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,1251646 0,1417825 ! female gamete generation GO:0007292 61 41 0,000 0,1251646 0,14171577 ! polyol metabolic process GO:0019751 66 41 0,000 0,1251646 0,14164912 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,1251646 0,14158252 ! regulation of tube size GO:0035150 71 42 0,000 0,12801517 0,14473896 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12801517 0,14467097 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12801517 0,14460305 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12801517 0,1445352 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12801517 0,1444674 ! neuron migration GO:0001764 79 42 0,000 0,12801517 0,14439967 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12801517 0,14433201 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,13085655 0,14746645 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,13085655 0,14739741 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,13085655 0,14732843 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,13085655 0,14725952 ! glucose transport GO:0015758 65 43 0,000 0,13085655 0,14719068 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,13085655 0,1471219 ! neural tube development GO:0021915 77 43 0,000 0,13085655 0,14705318 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,13085655 0,14698453 ! striated muscle contraction GO:0006941 77 43 0,000 0,13085655 0,14691594 ! phagocytosis GO:0006909 90 43 0,000 0,13085655 0,14684742 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,13085655 0,14677896 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13368877 0,14988592 ! hexose transport GO:0008645 67 44 0,000 0,13368877 0,1498161 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13368877 0,14974636 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13368877 0,14967668 ! developmental growth GO:0048589 82 44 0,000 0,13368877 0,14960706 ! maintenance of location in cell GO:0051651 97 44 0,000 0,13368877 0,14953751 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13651185 0,15262431 ! glycolysis GO:0006096 65 45 0,000 0,13651185 0,15255342 ! leukocyte migration GO:0050900 68 45 0,000 0,13651185 0,15248259 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13651185 0,15241184 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13651185 0,15234114 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13651185 0,15227052 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13651185 0,15219996 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13651185 0,15212946 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13651185 0,15205903 ! cell growth GO:0016049 84 45 0,000 0,13651185 0,15198867 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13932582 0,15504992 ! positive regulation of defense response GO:0031349 76 47 0,000 0,14213072 0,15809825 ! endosome transport GO:0016197 108 47 0,000 0,14213072 0,15802519 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,14213072 0,1579522 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,14213072 0,15787928 ! JNK cascade GO:0007254 91 47 0,000 0,14213072 0,15780642 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,14213072 0,15773363 ! protein homooligomerization GO:0051260 76 47 0,000 0,14213072 0,15766091 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14492657 0,16068817 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14492657 0,16061415 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,14492657 0,16054021 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14492657 0,16046633 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14492657 0,16039251 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,14492657 0,16031877 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,14492657 0,16024509 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,14492657 0,16017149 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,1477134 0,16317651 ! regulation of action potential GO:0001508 95 49 0,000 0,1477134 0,16310162 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,1477134 0,16302681 ! regulation of ion transport GO:0043269 77 49 0,000 0,1477134 0,16295206 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,1477134 0,16287738 ! peptide metabolic process GO:0006518 76 49 0,000 0,1477134 0,16280277 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,1477134 0,16272822 ! endocrine system development GO:0035270 104 49 0,000 0,1477134 0,16265375 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,1477134 0,16257934 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,1477134 0,162505 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,1477134 0,16243073 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,15049124 0,16540974 ! neuromuscular process GO:0050905 99 50 0,000 0,15049124 0,16533421 ! regulation of ossification GO:0030278 117 50 0,000 0,15049124 0,16525875 ! inner ear development GO:0048839 79 50 0,000 0,15049124 0,16518336 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,15049124 0,16510804 ! viral infectious cycle GO:0019058 99 51 0,000 0,15326012 0,16806921 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,15326012 0,16799264 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15326012 0,16791614 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15326012 0,16783971 ! excretion GO:0007588 83 51 0,000 0,15326012 0,16776335 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,15326012 0,16768706 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15326012 0,16761084 ! vesicle organization GO:0016050 107 51 0,000 0,15326012 0,16753469 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,15326012 0,1674586 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15326012 0,16738259 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,15602006 0,17031954 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,15602006 0,1702423 ! synapse organization GO:0050808 85 52 0,000 0,15602006 0,17016513 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1587711 0,17308712 ! RNA catabolic process GO:0006401 93 53 0,000 0,1587711 0,17300873 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,1587711 0,17293041 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,1587711 0,17285216 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,1587711 0,17277398 ! cell maturation GO:0048469 100 53 0,000 0,1587711 0,17269587 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,1587711 0,17261784 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,16151327 0,17551984 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,16151327 0,1754406 ! cell recognition GO:0008037 85 54 0,000 0,16151327 0,17536143 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,16151327 0,17528233 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,16151327 0,1752033 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,16151327 0,17512435 ! chloride transport GO:0006821 90 55 0,000 0,16424658 0,17800778 ! glucose catabolic process GO:0006007 82 55 0,000 0,16424658 0,17792764 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16424658 0,17784756 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,16424658 0,17776756 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,16424658 0,17768763 ! gastrulation GO:0007369 112 55 0,000 0,16424658 0,17760777 ! RNA elongation GO:0006354 79 55 0,000 0,16424658 0,17752798 ! nuclear export GO:0051168 97 55 0,000 0,16424658 0,17744826 ! regulation of actin filament length GO:0030832 105 56 0,000 0,16697108 0,18031078 ! sensory perception of smell GO:0007608 80 56 0,000 0,16697108 0,18022989 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,16697108 0,18014907 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16697108 0,18006832 ! proton transport GO:0015992 94 56 0,000 0,16697108 0,17998764 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,16697108 0,17990704 ! muscle fiber development GO:0048747 112 57 0,000 0,16968679 0,1827513 ! lipid modification GO:0030258 97 57 0,000 0,16968679 0,18266953 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,16968679 0,18258784 ! maintenance of location GO:0051235 118 57 0,000 0,16968679 0,18250622 ! hydrogen transport GO:0006818 97 58 0,000 0,17239373 0,18533481 ! regulation of endocytosis GO:0030100 91 58 0,000 0,17239373 0,18525204 ! adult behavior GO:0030534 99 58 0,000 0,17239373 0,18516934 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,17239373 0,18508671 ! positive regulation of secretion GO:0051047 95 59 0,000 0,17509194 0,18789973 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17509194 0,18781596 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17509194 0,18773226 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17509194 0,18764864 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,17509194 0,18756509 ! establishment of organelle localization GO:0051656 109 59 0,000 0,17509194 0,18748162 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,17778144 0,19027675 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,17778144 0,19019215 ! regulation of heart contraction GO:0008016 110 60 0,000 0,17778144 0,19010762 ! camera-type eye development GO:0043010 116 60 0,000 0,17778144 0,19002316 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,17778144 0,18993878 ! kidney development GO:0001822 122 60 0,000 0,17778144 0,18985448 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,18046226 0,19263185 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,18046226 0,19254643 ! tRNA processing GO:0008033 89 61 0,000 0,18046226 0,19246108 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,18046226 0,1923758 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,18313443 0,19513792 ! gonad development GO:0008406 98 62 0,000 0,18313443 0,19505154 ! regulation of mitosis GO:0007088 105 63 0,000 0,18579797 0,19780085 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,18579797 0,19771336 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,18579797 0,19762596 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,18579797 0,19753863 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,18579797 0,19745138 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18845292 0,20018442 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18845292 0,20009608 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18845292 0,20000782 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,18845292 0,19991963 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,18845292 0,19983152 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,1910993 0,20254842 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,1910993 0,20245923 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,1910993 0,20237012 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,19373713 0,20507327 ! actin filament organization GO:0007015 148 66 0,000 0,19373713 0,20498309 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19373713 0,20489299 ! secondary metabolic process GO:0019748 116 66 0,000 0,19373713 0,20480296 ! developmental maturation GO:0021700 116 66 0,000 0,19373713 0,20471302 ! cell projection assembly GO:0030031 120 66 0,000 0,19373713 0,20462315 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,19636646 0,20730921 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,19636646 0,20721829 ! negative regulation of protein kinase activity GO:0006469 130 67 0,000 0,19636646 0,20712744 ! chromosome segregation GO:0007059 113 67 0,000 0,19636646 0,20703668 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,19636646 0,20694599 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,19636646 0,20685538 ! hexose catabolic process GO:0019320 104 67 0,000 0,19636646 0,20676485 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,19636646 0,20667441 ! activation of immune response GO:0002253 105 67 0,000 0,19636646 0,20658404 ! amino acid transport GO:0006865 125 68 0,000 0,19898729 0,20924975 ! negative regulation of kinase activity GO:0033673 131 68 0,000 0,19898729 0,20915833 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19898729 0,209067 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19898729 0,20897574 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,19898729 0,20888456 ! regulation of lipase activity GO:0060191 130 68 0,000 0,19898729 0,20879347 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19898729 0,20870245 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,19898729 0,20861151 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,20159967 0,21125819 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,20159967 0,21116621 ! urogenital system development GO:0001655 137 69 0,000 0,20159967 0,21107432 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,20159967 0,21098251 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,20159967 0,21089078 ! antigen processing and presentation GO:0019882 104 69 0,000 0,20159967 0,21079913 ! appendage morphogenesis GO:0035107 135 70 0,000 0,20420361 0,21342914 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,20679914 0,21604808 ! reproductive structure development GO:0048608 113 71 0,000 0,20679914 0,21595431 ! appendage development GO:0048736 136 71 0,000 0,20679914 0,21586062 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,20679914 0,21576701 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,20679914 0,21567349 ! regulation of immune effector process GO:0002697 137 71 0,000 0,20679914 0,21558004 ! acute inflammatory response GO:0002526 113 72 0,000 0,2093863 0,21818252 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,2093863 0,21808807 ! carbohydrate transport GO:0008643 110 72 0,000 0,2093863 0,2179937 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,2093863 0,21789941 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,2093863 0,2178052 ! negative regulation of transferase activity GO:0051348 140 72 0,000 0,2093863 0,21771108 ! learning or memory GO:0007611 147 73 0,000 0,2119651 0,22029721 ! regulation of blood pressure GO:0008217 125 73 0,000 0,2119651 0,22020209 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,2119651 0,22010705 ! axon guidance GO:0007411 139 73 0,000 0,2119651 0,22001209 ! fertilization GO:0009566 90 73 0,000 0,2119651 0,21991722 ! transition metal ion transport GO:0000041 126 74 0,000 0,21453558 0,22248819 ! neurotransmitter transport GO:0006836 123 74 0,000 0,21453558 0,22239233 ! meiosis GO:0007126 121 74 0,000 0,21453558 0,22229656 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,21453558 0,22220086 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,21453558 0,22210525 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,21453558 0,22200972 ! eye development GO:0001654 143 74 0,000 0,21453558 0,22191427 ! organelle localization GO:0051640 136 74 0,000 0,21453558 0,22181891 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21709776 0,22437165 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,21709776 0,22427531 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,21709776 0,22417906 ! meiotic cell cycle GO:0051321 122 75 0,000 0,21709776 0,22408288 ! rhythmic process GO:0048511 128 75 0,000 0,21709776 0,22398679 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21965166 0,2265246 ! defense response to bacterium GO:0042742 89 76 0,000 0,21965166 0,22642755 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,21965166 0,22633058 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21965166 0,22623369 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,22219732 0,2287577 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,22219732 0,22865986 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,22219732 0,2285621 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,22219732 0,22846442 ! blood coagulation GO:0007596 146 78 0,000 0,22473476 0,23097472 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,22473476 0,2308761 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,22473476 0,23077756 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,227264 0,23327525 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,227264 0,23317578 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,227264 0,23307638 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,227264 0,23297707 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,22978508 0,2354612 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22978508 0,23536096 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22978508 0,23526081 ! inorganic anion transport GO:0015698 138 80 0,000 0,22978508 0,23516074 ! digestion GO:0007586 112 81 0,000 0,23229802 0,23763139 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,23229802 0,2375304 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,23480284 0,23998965 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,23480284 0,23988774 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,23480284 0,23978592 ! regulation of lyase activity GO:0051339 160 83 0,000 0,23729957 0,24223282 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,23978824 0,24466942 ! hemostasis GO:0007599 158 84 0,000 0,23978824 0,24456571 ! negative regulation of transport GO:0051051 153 84 0,000 0,23978824 0,24446208 ! regulation of ligase activity GO:0051340 142 84 0,000 0,23978824 0,24435853 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23978824 0,24425508 ! nucleosome assembly GO:0006334 122 85 0,000 0,24226887 0,24667748 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,24226887 0,24657314 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,24474148 0,24898436 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,24474148 0,24887913 ! chromatin assembly GO:0031497 124 86 0,000 0,24474148 0,24877398 ! tube morphogenesis GO:0035239 176 86 0,000 0,24474148 0,24866892 ! alcohol catabolic process GO:0046164 130 86 0,000 0,24474148 0,24856396 ! amine transport GO:0015837 155 86 0,000 0,24474148 0,24845908 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,24720612 0,2508553 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,24720612 0,25074954 ! cellular respiration GO:0045333 135 88 0,000 0,24966279 0,25313471 ! gland development GO:0048732 206 88 0,000 0,24966279 0,25302808 ! regulation of neurological system process GO:0031644 148 88 0,000 0,24966279 0,25292154 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,24966279 0,25281509 ! cellular defense response GO:0006968 114 89 0,000 0,25211152 0,25518734 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,25211152 0,25508003 ! ossification GO:0001503 188 90 0,000 0,25455234 0,25744134 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,25455234 0,25733317 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,25455234 0,25722509 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,25455234 0,2571171 ! bone development GO:0060348 189 91 0,000 0,25698528 0,25946563 ! sterol metabolic process GO:0016125 152 91 0,000 0,25698528 0,25935679 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,25698528 0,25924805 ! regulation of defense response GO:0031347 149 92 0,000 0,25941036 0,2615848 ! nucleosome organization GO:0034728 138 92 0,000 0,25941036 0,26147521 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25941036 0,26136572 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25941036 0,26125631 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,26182761 0,26358043 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,26182761 0,26347019 ! regulation of membrane potential GO:0042391 164 93 0,000 0,26182761 0,26336004 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,26423704 0,26567251 ! female pregnancy GO:0007565 164 94 0,000 0,26423704 0,26556154 ! regulation of T cell activation GO:0050863 158 94 0,000 0,26423704 0,26545066 ! forebrain development GO:0030900 188 95 0,000 0,2666387 0,26775154 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,2666387 0,26763984 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,26903259 0,26993011 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,26903259 0,26981759 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,27141874 0,27209729 ! protein ubiquitination GO:0016567 217 97 0,000 0,27141874 0,27198396 ! hormone metabolic process GO:0042445 157 97 0,000 0,27141874 0,27187073 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,27379719 0,27413901 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,27379719 0,27402497 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,27616795 0,27628278 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,27616795 0,27616795