pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/573-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 2,000 6,289E-07 1,513E-03 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 3,000 1,143E-06 1,375E-03 ! negative regulation of translation GO:0017148 29 20 3,000 1,143E-06 9,164E-04 ! nuclear migration GO:0007097 12 6 2,000 1,254E-06 7,543E-04 ! male sex determination GO:0030238 15 6 2,000 1,254E-06 6,035E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,254E-06 5,029E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of intracellular transport GO:0032388 37 22 3,000 1,714E-06 5,893E-04 ! sex determination GO:0007530 47 23 3,000 2,069E-06 6,223E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 2,188E-06 5,85E-04 ! adrenal gland development GO:0030325 17 7 2,000 2,188E-06 5,265E-04 ! macrophage differentiation GO:0030225 11 7 2,000 2,188E-06 4,786E-04 ! interaction with host GO:0051701 62 25 3,000 2,937E-06 5,889E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 3,461E-06 6,405E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 3,491E-06 5,999E-04 ! cell junction assembly GO:0034329 78 30 3,000 6,266E-06 1,005E-03 ! protein sumoylation GO:0016925 15 10 2,000 7,436E-06 1,118E-03 ! nucleus localization GO:0051647 19 11 2,000 1,019E-05 1,443E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 3,000 1,047E-05 1,4E-03 ! cell junction organization GO:0034330 86 36 3,000 1,322E-05 1,674E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,355E-05 1,63E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 1,478E-05 1,693E-03 ! filopodium assembly GO:0046847 32 16 2,000 3,41E-05 3,729E-03 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 2,000 3,41E-05 3,567E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 3,55E-05 3,559E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 3,55E-05 3,417E-03 ! microspike assembly GO:0030035 36 17 2,000 4,128E-05 3,82E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 4,939E-05 4,401E-03 ! nuclear export GO:0051168 97 55 3,000 7,216E-05 6,2E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 8,306E-05 6,891E-03 ! keratinization GO:0031424 28 22 2,000 9,213E-05 7,389E-03 ! cellular response to reactive oxygen species GO:0034614 31 22 2,000 9,213E-05 7,15E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 1,056E-04 7,943E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,056E-04 7,702E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 1,084E-04 7,669E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 1,229E-04 8,452E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,389E-04 9,282E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 1,537E-04 9,996E-03 ! protein maturation by protein folding GO:0022417 13 5 1,000 1,588E-04 0,0100562 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,588E-04 9,798E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,588E-04 9,553E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,588E-04 9,32E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,588E-04 9,098E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,724E-04 9,648E-03 ! spliceosomal snRNP biogenesis GO:0000387 36 27 2,000 1,724E-04 9,429E-03 ! male gonad development GO:0008584 44 27 2,000 1,724E-04 9,22E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 2,142E-04 0,01120124 ! interaction with symbiont GO:0051702 13 6 1,000 2,376E-04 0,01216372 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 1,000 2,376E-04 0,01191031 ! cell-matrix adhesion GO:0007160 163 75 3,000 2,417E-04 0,01186946 ! cell-substrate adhesion GO:0031589 171 81 3,000 3,248E-04 0,01562992 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,318E-04 0,01565229 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,318E-04 0,01535129 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 1,000 3,318E-04 0,01506164 GO:0031958|corticosteroid receptor signaling pathway, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,318E-04 0,01478272 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 3,318E-04 0,01451394 ! regulation of meiosis GO:0040020 12 7 1,000 3,318E-04 0,01425476 GO:0051445|regulation of meiotic cell cycle, ! regulation of respiratory burst GO:0060263 11 7 1,000 3,318E-04 0,01400468 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 3,404E-04 0,01412137 ! protein localization in nucleus GO:0034504 176 87 3,000 4,266E-04 0,01739604 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 4,412E-04 0,0176926 ! ER overload response GO:0006983 12 8 1,000 4,412E-04 0,01740256 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 4,412E-04 0,01712187 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 1,000 4,412E-04 0,0168501 ! RNA export from nucleus GO:0006405 56 37 2,000 4,448E-04 0,01672333 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 4,448E-04 0,01646605 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 4,816E-04 0,01755512 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 5,202E-04 0,01867947 ! regulation of developmental growth GO:0048638 15 9 1,000 5,658E-04 0,02001866 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,658E-04 0,01972854 ! regulation of glycolysis GO:0006110 21 9 1,000 5,658E-04 0,0194467 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,658E-04 0,0191728 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 5,658E-04 0,01890651 ! protein heterooligomerization GO:0051291 16 9 1,000 5,658E-04 0,01864752 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 5,658E-04 0,01839553 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 5,658E-04 0,01815025 ! regulation of telomere maintenance GO:0032204 14 9 1,000 5,658E-04 0,01791143 ! keratinocyte differentiation GO:0030216 62 41 2,000 6,032E-04 0,01884807 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 6,439E-04 0,01986062 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 6,477E-04 0,01972629 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 2,000 6,477E-04 0,01947971 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 7,054E-04 0,02095202 ! positive regulation of phagocytosis GO:0050766 13 10 1,000 7,054E-04 0,0206965 ! apical protein localization GO:0045176 15 10 1,000 7,054E-04 0,02044715 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 7,054E-04 0,02020373 GO:0043470|regulation of carbohydrate catabolic process, ! male sex differentiation GO:0046661 76 44 2,000 7,429E-04 0,02102771 ! epidermal cell differentiation GO:0009913 68 46 2,000 8,465E-04 0,02368247 ! pigmentation GO:0043473 100 46 2,000 8,465E-04 0,02341026 ! cortical actin cytoskeleton organization GO:0030866 30 11 1,000 8,598E-04 0,02350908 ! detection of mechanical stimulus GO:0050982 22 11 1,000 8,598E-04 0,02324493 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 8,598E-04 0,02298665 ! DNA methylation GO:0006306 19 11 1,000 8,598E-04 0,02273405 GO:0006305|DNA alkylation, ! T cell receptor signaling pathway GO:0050852 23 11 1,000 8,598E-04 0,02248694 ! sequestering of metal ion GO:0051238 14 11 1,000 8,598E-04 0,02224515 ! regulation of embryonic development GO:0045995 27 11 1,000 8,598E-04 0,0220085 ! positive regulation of DNA binding GO:0043388 73 47 2,000 9,016E-04 0,02283381 ! activation of caspase activity GO:0006919 84 48 2,000 9,589E-04 0,02403206 ! endocrine system development GO:0035270 104 49 2,000 1,018E-03 0,02526158 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,029E-03 0,02526568 ! cortical cytoskeleton organization GO:0030865 31 12 1,000 1,029E-03 0,02501047 ! virus-host interaction GO:0019048 29 12 1,000 1,029E-03 0,02476037 ! focal adhesion formation GO:0048041 35 12 1,000 1,029E-03 0,02451521 ! asymmetric protein localization GO:0008105 20 12 1,000 1,029E-03 0,02427487 ! entry into host cell GO:0030260 32 12 1,000 1,029E-03 0,02403919 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 16 12 1,000 1,029E-03 0,02380804 ! histone acetylation GO:0016573 26 12 1,000 1,029E-03 0,0235813 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,029E-03 0,02335884 ! regulation of steroid biosynthetic process GO:0050810 17 12 1,000 1,029E-03 0,02314053 ! regulation of cell projection organization GO:0031344 121 50 2,000 1,08E-03 0,02406649 ! positive regulation of binding GO:0051099 78 51 2,000 1,144E-03 0,0252622 ! regulation of cell shape GO:0008360 125 51 2,000 1,144E-03 0,02503254 ! cell-cell junction assembly GO:0007043 27 13 1,000 1,213E-03 0,02629315 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,213E-03 0,02605839 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,213E-03 0,02582779 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! actin filament polymerization GO:0030041 24 13 1,000 1,213E-03 0,02560123 ! regulation of translational initiation GO:0006446 82 53 2,000 1,28E-03 0,026778 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,411E-03 0,02927607 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,411E-03 0,02902584 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,411E-03 0,02877986 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,425E-03 0,0288123 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 1,425E-03 0,0285722 ! regulation of DNA replication GO:0006275 101 56 2,000 1,501E-03 0,0298528 ! maintenance of location GO:0051235 118 57 2,000 1,58E-03 0,031162 ! pituitary gland development GO:0021983 29 15 1,000 1,624E-03 0,03177402 ! cell killing GO:0001906 29 15 1,000 1,624E-03 0,03151777 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 1,745E-03 0,03359482 ! establishment of organelle localization GO:0051656 109 59 2,000 1,745E-03 0,0333282 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 1,832E-03 0,03470478 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,852E-03 0,03480312 ! complement activation, alternative pathway GO:0006957 18 16 1,000 1,852E-03 0,03453333 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,921E-03 0,0355538 ! viral reproductive process GO:0022415 126 62 2,000 2,013E-03 0,03696856 ! gonad development GO:0008406 98 62 2,000 2,013E-03 0,03668849 ! regulation of homeostatic process GO:0032844 134 62 2,000 2,013E-03 0,03641264 ! limbic system development GO:0021761 36 17 1,000 2,093E-03 0,03757858 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,093E-03 0,03730022 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,093E-03 0,03702595 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,093E-03 0,03675569 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 2,093E-03 0,03648935 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 2,304E-03 0,03988924 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 2,348E-03 0,04035797 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,348E-03 0,04007174 ! memory GO:0007613 31 18 1,000 2,348E-03 0,03978955 ! cellular response to hydrogen peroxide GO:0070301 23 18 1,000 2,348E-03 0,0395113 GO:0042744|hydrogen peroxide catabolic process, ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,348E-03 0,03923692 ! regulation of steroid metabolic process GO:0019218 30 18 1,000 2,348E-03 0,03896632 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,348E-03 0,03869942 ! actin filament organization GO:0007015 148 66 2,000 2,407E-03 0,03939964 ! cell projection assembly GO:0030031 120 66 2,000 2,407E-03 0,03913343 ! activation of immune response GO:0002253 105 67 2,000 2,513E-03 0,04057458 ! lipid phosphorylation GO:0046834 35 19 1,000 2,618E-03 0,04198855 ! actin filament bundle formation GO:0051017 42 19 1,000 2,618E-03 0,04171048 ! response to lipopolysaccharide GO:0032496 30 19 1,000 2,618E-03 0,04143606 ! peptide cross-linking GO:0018149 37 19 1,000 2,618E-03 0,04116524 ! protein export from nucleus GO:0006611 36 19 1,000 2,618E-03 0,04089793 ! cellular pigmentation GO:0033059 36 19 1,000 2,618E-03 0,04063408 ! cell-cell junction organization GO:0045216 35 19 1,000 2,618E-03 0,0403736 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 2,618E-03 0,04011644 ! negative regulation of kinase activity GO:0033673 131 68 2,000 2,621E-03 0,03991305 ! viral reproduction GO:0016032 134 68 2,000 2,621E-03 0,03966202 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,901E-03 0,04362345 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,901E-03 0,04335249 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 2,901E-03 0,04308489 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 2,901E-03 0,04282056 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,901E-03 0,04255946 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 2,901E-03 0,04230153 ! diencephalon development GO:0021536 34 20 1,000 2,901E-03 0,0420467 ! peptidyl-serine modification GO:0018209 43 20 1,000 2,901E-03 0,04179492 ! reproductive structure development GO:0048608 113 71 2,000 2,963E-03 0,04243755 ! acute inflammatory response GO:0002526 113 72 2,000 3,083E-03 0,0438928 ! regulation of caspase activity GO:0043281 122 72 2,000 3,083E-03 0,04363461 ! negative regulation of transferase activity GO:0051348 140 72 2,000 3,083E-03 0,04337944 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 3,198E-03 0,04473402 ! cell aging GO:0007569 44 21 1,000 3,198E-03 0,04447545 ! cytolysis GO:0019835 24 21 1,000 3,198E-03 0,04421984 ! DNA modification GO:0006304 34 21 1,000 3,198E-03 0,04396716 ! learning or memory GO:0007611 147 73 2,000 3,206E-03 0,04382576 ! regulation of transcription factor activity GO:0051090 126 74 2,000 3,332E-03 0,04528764 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 3,332E-03 0,04503322 ! organelle localization GO:0051640 136 74 2,000 3,332E-03 0,04478164 ! microtubule-based transport GO:0010970 54 22 1,000 3,509E-03 0,04689728 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,509E-03 0,04663818 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,509E-03 0,04638193 ! protein stabilization GO:0050821 39 22 1,000 3,509E-03 0,04612848 ! development of primary sexual characteristics GO:0045137 124 76 2,000 3,592E-03 0,04697106 ! gluconeogenesis GO:0006094 33 23 1,000 3,833E-03 0,04984464 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 3,833E-03 0,04957666 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,833E-03 0,04931154 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 3,833E-03 0,04904925 ! blood coagulation GO:0007596 146 78 2,000 3,865E-03 0,0491989 GO:0050817|coagulation, ! regulation of peptidase activity GO:0052547 134 79 2,000 4,006E-03 0,05072426 ! protein import into nucleus GO:0006606 158 80 2,000 4,15E-03 0,05227261 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 4,17E-03 0,05225638 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 4,17E-03 0,05198562 ! protein tetramerization GO:0051262 52 24 1,000 4,17E-03 0,05171766 ! nuclear import GO:0051170 161 81 2,000 4,297E-03 0,05301545 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 4,521E-03 0,05549564 ! hydrogen peroxide metabolic process GO:0042743 33 25 1,000 4,521E-03 0,05521393 ! somitogenesis GO:0001756 43 25 1,000 4,521E-03 0,05493508 ! hemostasis GO:0007599 158 84 2,000 4,757E-03 0,05751378 ! initiation of viral infection GO:0019059 57 26 1,000 4,885E-03 0,05876376 ! pyruvate metabolic process GO:0006090 38 26 1,000 4,885E-03 0,0584714 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 4,885E-03 0,05818194 ! mitochondrion organization GO:0007005 148 86 2,000 5,08E-03 0,0602053 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,262E-03 0,06205775 ! protein amino acid acylation GO:0043543 55 27 1,000 5,262E-03 0,06175503 ! regulation of chromosome organization GO:0033044 42 27 1,000 5,262E-03 0,06145525 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 5,262E-03 0,06115836 ! regulation of DNA binding GO:0051101 155 88 2,000 5,415E-03 0,0626401 ! gland development GO:0048732 206 88 2,000 5,415E-03 0,06234039 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 5,588E-03 0,06402197 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 5,652E-03 0,06444536 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 1,000 5,652E-03 0,06414137 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 5,652E-03 0,06384024 ! sex differentiation GO:0007548 145 90 2,000 5,764E-03 0,06480359 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 6,054E-03 0,06775377 ! complement activation, classical pathway GO:0006958 48 29 1,000 6,054E-03 0,0674401 ! immune response-activating signal transduction GO:0002757 47 29 1,000 6,054E-03 0,06712931 GO:0002764|immune response-regulating signal transduction, ! acute-phase response GO:0006953 49 30 1,000 6,47E-03 0,0714073 ! leukocyte differentiation GO:0002521 202 96 2,000 6,889E-03 0,07568827 ! mRNA transport GO:0051028 169 96 2,000 6,889E-03 0,07534423 ! positive regulation of immune response GO:0050778 156 96 2,000 6,889E-03 0,0750033 ! ovulation cycle process GO:0022602 49 31 1,000 6,898E-03 0,07476083 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 6,898E-03 0,07442558 ! iron ion homeostasis GO:0055072 54 31 1,000 6,898E-03 0,07409333 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 7,339E-03 0,0784762 ! response to hydrogen peroxide GO:0042542 50 32 1,000 7,339E-03 0,07812896 ! response to mechanical stimulus GO:0009612 57 32 1,000 7,339E-03 0,07778478 ! hexose biosynthetic process GO:0019319 48 32 1,000 7,339E-03 0,07744362 ! ovulation cycle GO:0042698 51 32 1,000 7,339E-03 0,07710544 ! positive regulation of catabolic process GO:0009896 64 32 1,000 7,339E-03 0,0767702 ! cell cycle arrest GO:0007050 213 100 2,000 7,707E-03 0,0802735 ! positive regulation of endocytosis GO:0045807 50 34 1,000 8,257E-03 0,08563358 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 1,000 8,257E-03 0,08526605 ! female gonad development GO:0008585 58 35 1,000 8,735E-03 0,08981235 ! maintenance of protein location in cell GO:0032507 86 36 1,000 9,225E-03 0,09444386 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 9,225E-03 0,09404367 ! regulation of protein stability GO:0031647 73 37 1,000 9,726E-03 0,09874006 ! glycogen metabolic process GO:0005977 61 37 1,000 9,726E-03 0,09832518 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,01023986 0,10308411 GO:0006956|complement activation, ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,01023986 0,10265459 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01023986 0,10222864 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01023986 0,10180621 ! glucan metabolic process GO:0044042 62 38 1,000 0,01023986 0,10138725 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,01076525 0,10615241 ! ear morphogenesis GO:0042471 60 39 1,000 0,01076525 0,10571913 ! segmentation GO:0035282 67 39 1,000 0,01076525 0,10528938 ! feeding behavior GO:0007631 59 40 1,000 0,01130233 0,11009476 ! maintenance of protein location GO:0045185 91 40 1,000 0,01130233 0,10965083 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,011851 0,1145121 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,01241117 0,11944508 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01241117 0,1189692 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01241117 0,1184971 ! neuron migration GO:0001764 79 42 1,000 0,01241117 0,11802873 ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,01241117 0,11756405 ! receptor-mediated endocytosis GO:0006898 88 43 1,000 0,01298272 0,12249583 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01298272 0,12201733 ! glucose transport GO:0015758 65 43 1,000 0,01298272 0,12154255 ! hexose transport GO:0008645 67 44 1,000 0,01356557 0,12650687 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 0,01356557 0,12601843 ! maintenance of location in cell GO:0051651 97 44 1,000 0,01356557 0,12553374 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01415962 0,13052891 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,01415962 0,1300307 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01476476 0,1350723 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01476476 0,13456066 ! methylation GO:0032259 90 47 1,000 0,0153809 0,13964698 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,01600795 0,14479368 ! cellular component disassembly GO:0022411 86 48 1,000 0,01600795 0,14425138 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,0166458 0,14943951 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,0166458 0,14888397 ! histone modification GO:0016570 91 50 1,000 0,01729436 0,15411197 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01729436 0,15354329 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01729436 0,15297879 ! viral infectious cycle GO:0019058 99 51 1,000 0,01795354 0,1582279 ! excretion GO:0007588 83 51 1,000 0,01795354 0,15765043 ! positive regulation of growth GO:0045927 90 52 1,000 0,01862324 0,16293643 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01862324 0,16234609 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,01930337 0,16766756 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01992887 0,17247788 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01992887 0,17185968 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01992887 0,1712459 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01992887 0,17063648 ! neuron fate determination GO:0048664 7 5 0,000 0,01992887 0,17003139 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01992887 0,16943057 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01992887 0,16883398 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01992887 0,16824158 ! polyol transport GO:0015791 12 5 0,000 0,01992887 0,16765333 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01992887 0,16706917 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01992887 0,16648907 ! response to superoxide GO:0000303 10 5 0,000 0,01992887 0,16591298 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01992887 0,16534087 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01992887 0,16477269 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01992887 0,1642084 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01992887 0,16364796 ! female meiosis GO:0007143 7 5 0,000 0,01992887 0,16309133 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01992887 0,16253848 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01992887 0,16198936 ! cobalt ion transport GO:0006824 11 5 0,000 0,01992887 0,16144394 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01992887 0,16090219 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01992887 0,16036405 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01992887 0,15982951 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01992887 0,15929851 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01992887 0,15877103 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01992887 0,15824703 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01992887 0,15772649 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01992887 0,15720935 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01992887 0,15669559 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01992887 0,15618518 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01992887 0,15567809 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01992887 0,15517428 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01992887 0,15467371 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01992887 0,15417637 ! negative chemotaxis GO:0050919 14 5 0,000 0,01992887 0,15368222 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01992887 0,15319122 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01992887 0,15270335 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01992887 0,15221858 ! behavioral response to pain GO:0048266 9 5 0,000 0,01992887 0,15173687 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01992887 0,15125821 ! Notch receptor processing GO:0007220 8 5 0,000 0,01992887 0,15078255 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01992887 0,15030988 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01992887 0,14984016 ! micturition GO:0060073 9 5 0,000 0,01992887 0,14937337 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01992887 0,14890948 ! copulation GO:0007620 9 5 0,000 0,01992887 0,14844846 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01992887 0,14799028 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01992887 0,14753493 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01992887 0,14708237 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01992887 0,14663257 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01992887 0,14618552 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01992887 0,14574119 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01992887 0,14529955 ! grooming behavior GO:0007625 6 5 0,000 0,01992887 0,14486058 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01992887 0,14442425 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01992887 0,14399055 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01992887 0,14355944 ! response to protozoan GO:0001562 10 5 0,000 0,01992887 0,1431309 ! lymph vessel development GO:0001945 10 5 0,000 0,01992887 0,14270492 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01992887 0,14228146 ! endochondral ossification GO:0001958 16 5 0,000 0,01992887 0,14186051 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01992887 0,14144204 ! parathyroid gland development GO:0060017 13 5 0,000 0,01992887 0,14102603 ! anagen GO:0042640 6 5 0,000 0,01992887 0,14061247 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01992887 0,14020132 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01992887 0,13979257 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01992887 0,1393862 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01992887 0,13898218 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01992887 0,1385805 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01992887 0,13818113 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01992887 0,13778406 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01992887 0,13738926 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01992887 0,13699672 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01992887 0,13660641 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01992887 0,13621833 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01992887 0,13583244 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01992887 0,13544873 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01992887 0,13506719 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01992887 0,13468779 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01992887 0,13431051 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01992887 0,13393534 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01992887 0,13356226 ! histidine catabolic process GO:0006548 6 5 0,000 0,01992887 0,13319125 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01992887 0,1328223 ! microvillus organization GO:0032528 7 5 0,000 0,01992887 0,13245539 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01992887 0,1320905 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01992887 0,13172761 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01992887 0,13136672 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01992887 0,13100779 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01992887 0,13065082 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01992887 0,13029579 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01992887 0,12994269 ! polyol catabolic process GO:0046174 7 5 0,000 0,01992887 0,12959149 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01992887 0,12924219 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01992887 0,12889476 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01992887 0,1285492 ! muscle cell migration GO:0014812 8 5 0,000 0,01992887 0,12820549 ! mitochondrial fission GO:0000266 8 5 0,000 0,01992887 0,1278636 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01992887 0,12752354 ! mRNA transcription GO:0009299 9 5 0,000 0,01992887 0,12718528 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01992887 0,12684881 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01992887 0,12651412 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01992887 0,12618119 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01992887 0,12585 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01992887 0,12552055 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01992887 0,12519282 ! response to food GO:0032094 6 5 0,000 0,01992887 0,1248668 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01992887 0,12454247 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01992887 0,12421982 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01992887 0,12389884 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01992887 0,12357951 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01992887 0,12326183 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01992887 0,12294577 ! forebrain neuron development GO:0021884 13 5 0,000 0,01992887 0,12263133 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01992887 0,1223185 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01992887 0,12200726 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01992887 0,12169759 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01992887 0,1213895 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01992887 0,12108296 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01992887 0,12077796 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01992887 0,1204745 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01992887 0,12017256 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01992887 0,11987213 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01992887 0,1195732 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01992887 0,11927575 ! basic amino acid transport GO:0015802 11 5 0,000 0,01992887 0,11897978 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01992887 0,11868528 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01992887 0,11839223 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01992887 0,11810062 ! depyrimidination GO:0045008 10 5 0,000 0,01992887 0,11781045 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01992887 0,1175217 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01992887 0,11723436 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01992887 0,11694842 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01992887 0,11666387 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01992887 0,11638071 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01992887 0,11609891 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01992887 0,11581848 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01992887 0,1155394 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01992887 0,11526166 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01992887 0,11498526 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01992887 0,11471017 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01992887 0,1144364 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01992887 0,11416393 ! response to arsenic GO:0046685 10 5 0,000 0,01992887 0,11389276 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01992887 0,11362287 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01992887 0,11335426 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01992887 0,11308691 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01992887 0,11282083 ! response to cadmium ion GO:0046686 7 5 0,000 0,01992887 0,11255599 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01992887 0,11229239 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01992887 0,11203003 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01992887 0,11176888 ! decidualization GO:0046697 11 5 0,000 0,01992887 0,11150896 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01992887 0,11125024 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01992887 0,11099271 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01992887 0,11073638 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01992887 0,11048122 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01992887 0,11022724 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01992887 0,10997443 ! neural tube patterning GO:0021532 7 5 0,000 0,01992887 0,10972277 ! embryonic cleavage GO:0040016 6 5 0,000 0,01992887 0,10947226 ! peroxisome fission GO:0016559 5 5 0,000 0,01992887 0,1092229 ! histone demethylation GO:0016577 10 5 0,000 0,01992887 0,10897466 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01992887 0,10872755 ! mitotic recombination GO:0006312 9 5 0,000 0,01992887 0,10848156 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01992887 0,10823669 ! metaphase plate congression GO:0051310 7 5 0,000 0,01992887 0,10799291 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01992887 0,10775023 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01992887 0,10750864 ! enteric nervous system development GO:0048484 8 5 0,000 0,01992887 0,10726812 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01992887 0,10702869 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01992887 0,10679032 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01992887 0,106553 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01992887 0,10631674 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01992887 0,10608153 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01992887 0,10584735 ! plasminogen activation GO:0031639 5 5 0,000 0,01992887 0,10561421 ! B cell homeostasis GO:0001782 13 5 0,000 0,01992887 0,10538209 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01992887 0,10515099 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01992887 0,1049209 ! metaphase GO:0051323 8 5 0,000 0,01992887 0,10469182 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01992887 0,10446373 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01992887 0,10423663 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01992887 0,10401052 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01992887 0,10378539 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01992887 0,10356123 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01992887 0,10333804 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01992887 0,10311581 ! response to redox state GO:0051775 5 5 0,000 0,01992887 0,10289453 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01992887 0,1026742 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01992887 0,10245481 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01992887 0,10223636 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01992887 0,10201883 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01992887 0,10180223 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01992887 0,10158655 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01992887 0,10137178 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01992887 0,10115791 ! striatum development GO:0021756 9 5 0,000 0,01992887 0,10094495 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01992887 0,10073288 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01992887 0,1005217 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01992887 0,1003114 ! glial cell migration GO:0008347 11 5 0,000 0,01992887 0,10010199 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01992887 0,09989344 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01992887 0,09968576 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01992887 0,09947895 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01992887 0,09927298 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01992887 0,09906788 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01992887 0,09886361 ! neuroprotection GO:0043526 6 5 0,000 0,01992887 0,09866019 ! neural plate development GO:0001840 8 5 0,000 0,01992887 0,0984576 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01992887 0,09825584 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01992887 0,09805491 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01992887 0,0978548 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01992887 0,0976555 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01992887 0,09745702 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01992887 0,09725933 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01992887 0,09706245 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01992887 0,09686637 ! spindle assembly GO:0051225 6 5 0,000 0,01992887 0,09667107 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01992887 0,09647656 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01992887 0,09628283 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01992887 0,09608988 ! drug metabolic process GO:0017144 6 5 0,000 0,01992887 0,0958977 ! stem cell division GO:0017145 11 5 0,000 0,01992887 0,09570629 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01992887 0,09551564 ! organ regeneration GO:0031100 7 5 0,000 0,01992887 0,09532575 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01992887 0,09513661 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01992887 0,09494822 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01992887 0,09476058 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02069455 0,09820726 ! heart morphogenesis GO:0003007 97 55 1,000 0,02069455 0,09801394 ! regulation of actin filament length GO:0030832 105 56 1,000 0,02140541 0,10118155 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,02212633 0,1043842 ! lipid modification GO:0030258 97 57 1,000 0,02212633 0,10417993 ! regulation of endocytosis GO:0030100 91 58 1,000 0,02285722 0,10741106 ! regulation of cellular component size GO:0032535 109 59 1,000 0,02359798 0,11067592 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02359798 0,11046059 ! DNA catabolic process GO:0006308 86 59 1,000 0,02359798 0,11024611 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02386712 0,11128737 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02386712 0,11107211 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02386712 0,11085769 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02386712 0,11064409 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02386712 0,11043131 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02386712 0,11021935 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02386712 0,1100082 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02386712 0,10979786 ! sleep GO:0030431 13 6 0,000 0,02386712 0,10958833 ! response to oxygen radical GO:0000305 11 6 0,000 0,02386712 0,10937959 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02386712 0,10917164 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02386712 0,10896448 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02386712 0,10875811 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02386712 0,10855252 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02386712 0,1083477 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02386712 0,10814366 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02386712 0,10794038 ! forebrain regionalization GO:0021871 8 6 0,000 0,02386712 0,10773787 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02386712 0,10753611 ! male meiosis GO:0007140 7 6 0,000 0,02386712 0,10733511 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02386712 0,10713486 ! response to zinc ion GO:0010043 9 6 0,000 0,02386712 0,10693535 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02386712 0,10673659 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02386712 0,10653856 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02386712 0,10634126 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02386712 0,1061447 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02386712 0,10594886 ! malate metabolic process GO:0006108 11 6 0,000 0,02386712 0,10575374 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02386712 0,10555934 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02386712 0,10536566 ! protein refolding GO:0042026 15 6 0,000 0,02386712 0,10517268 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02386712 0,10498041 ! opsonization GO:0008228 8 6 0,000 0,02386712 0,10478884 ! mating behavior GO:0007617 7 6 0,000 0,02386712 0,10459797 ! neuron remodeling GO:0016322 15 6 0,000 0,02386712 0,10440779 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02386712 0,1042183 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02386712 0,1040295 ! equilibrioception GO:0050957 14 6 0,000 0,02386712 0,10384138 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02386712 0,10365394 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02386712 0,10346718 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02386712 0,10328108 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02386712 0,10309566 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02386712 0,1029109 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02386712 0,1027268 ! toxin metabolic process GO:0009404 11 6 0,000 0,02386712 0,10254336 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02386712 0,10236058 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02386712 0,10217844 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02386712 0,10199695 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02386712 0,1018161 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02386712 0,1016359 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02386712 0,10145633 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02386712 0,10127739 ! thymic T cell selection GO:0045061 12 6 0,000 0,02386712 0,10109909 ! protein lipoylation GO:0009249 10 6 0,000 0,02386712 0,10092141 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02386712 0,10074436 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02386712 0,10056792 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02386712 0,1003921 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02386712 0,1002169 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02386712 0,1000423 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02386712 0,09986832 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02386712 0,09969494 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02386712 0,09952215 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02386712 0,09934997 ! hyperosmotic response GO:0006972 9 6 0,000 0,02386712 0,09917838 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02386712 0,09900738 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02386712 0,09883698 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02386712 0,09866715 ! urea metabolic process GO:0019627 7 6 0,000 0,02386712 0,09849791 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02386712 0,09832925 ! neutrophil activation GO:0042119 8 6 0,000 0,02386712 0,09816117 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02386712 0,09799366 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02386712 0,09782672 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02386712 0,09766035 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02386712 0,09749454 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02386712 0,09732929 ! neuron apoptosis GO:0051402 9 6 0,000 0,02386712 0,09716461 ! nucleoside salvage GO:0043174 9 6 0,000 0,02386712 0,09700048 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02386712 0,0968369 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02386712 0,09667388 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02386712 0,0965114 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02386712 0,09634947 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02386712 0,09618808 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02386712 0,09602723 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02386712 0,09586692 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02386712 0,09570714 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02386712 0,09554789 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02386712 0,09538917 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02386712 0,09523098 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02386712 0,09507332 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02386712 0,09491617 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02386712 0,09475954 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02386712 0,09460343 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02386712 0,09444783 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02386712 0,09429275 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02386712 0,09413817 ! neural nucleus development GO:0048857 14 6 0,000 0,02386712 0,0939841 ! response to UV-C GO:0010225 11 6 0,000 0,02386712 0,09383053 ! astrocyte development GO:0014002 15 6 0,000 0,02386712 0,09367746 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02386712 0,09352489 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02386712 0,09337282 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02386712 0,09322124 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02386712 0,09307015 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02386712 0,09291955 ! response to copper ion GO:0046688 10 6 0,000 0,02386712 0,09276944 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02386712 0,09261981 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02386712 0,09247066 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02386712 0,092322 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02386712 0,09217381 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02386712 0,09202609 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02386712 0,09187885 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02386712 0,09173208 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02386712 0,09158578 ! hair follicle maturation GO:0048820 7 6 0,000 0,02386712 0,09143994 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02386712 0,09129457 ! Schwann cell development GO:0014044 15 6 0,000 0,02386712 0,09114966 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02386712 0,0910052 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02386712 0,09086121 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02386712 0,09071767 ! subpallium development GO:0021544 10 6 0,000 0,02386712 0,09057458 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02386712 0,09043194 ! histone ubiquitination GO:0016574 8 6 0,000 0,02386712 0,09028975 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02386712 0,09014801 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02386712 0,09000671 ! G2 phase GO:0051319 16 6 0,000 0,02386712 0,08986586 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02386712 0,08972544 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02386712 0,08958546 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02386712 0,08944592 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02386712 0,08930682 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02386712 0,08916814 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02386712 0,0890299 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02386712 0,08889208 ! receptor internalization GO:0031623 10 6 0,000 0,02386712 0,08875469 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02386712 0,08861772 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02386712 0,08848118 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02386712 0,08834505 ! protein deubiquitination GO:0016579 14 6 0,000 0,02386712 0,08820934 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,02386712 0,08807405 ! protein destabilization GO:0031648 9 6 0,000 0,02386712 0,08793918 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02386712 0,08780471 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02386712 0,08767066 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02386712 0,08753702 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02386712 0,08740378 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02386712 0,08727095 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02386712 0,08713852 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02386712 0,08700649 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02386712 0,08687486 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02386712 0,08674363 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02386712 0,08661279 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02386712 0,08648235 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02386712 0,08635231 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02386712 0,08622265 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02386712 0,08609338 ! catecholamine transport GO:0051937 9 6 0,000 0,02386712 0,0859645 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02386712 0,085836 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02386712 0,08570788 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02386712 0,08558015 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02386712 0,0854528 ! maternal placenta development GO:0001893 12 6 0,000 0,02386712 0,08532583 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02386712 0,08519923 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02386712 0,08507301 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02386712 0,08494716 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02386712 0,08482169 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02386712 0,08469658 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02386712 0,08457185 ! ear development GO:0043583 103 62 1,000 0,02587866 0,09156478 ! detection of external stimulus GO:0009581 91 63 1,000 0,02665804 0,09418393 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,02665804 0,09404583 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,02744687 0,09668692 ! cell redox homeostasis GO:0045454 102 64 1,000 0,02744687 0,09654556 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,02744687 0,09640462 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,02744687 0,09626409 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 1,000 0,02744687 0,09612396 ! tRNA transcription GO:0009304 14 7 0,000 0,02778967 0,09718307 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02778967 0,09704202 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02778967 0,09690138 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02778967 0,09676115 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02778967 0,09662132 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02778967 0,09648189 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02778967 0,09634287 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02778967 0,09620425 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02778967 0,09606602 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02778967 0,0959282 ! prostate gland development GO:0030850 13 7 0,000 0,02778967 0,09579076 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02778967 0,09565372 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02778967 0,09551707 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02778967 0,09538082 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02778967 0,09524495 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02778967 0,09510946 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02778967 0,09497436 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02778967 0,09483965 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02778967 0,09470531 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02778967 0,09457136 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02778967 0,09443779 ! glycolipid transport GO:0046836 10 7 0,000 0,02778967 0,09430459 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02778967 0,09417176 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02778967 0,09403931 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02778967 0,09390724 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02778967 0,09377553 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02778967 0,09364419 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02778967 0,09351322 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02778967 0,09338261 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02778967 0,09325237 ! mRNA stabilization GO:0048255 18 7 0,000 0,02778967 0,0931225 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02778967 0,09299298 ! fibril organization GO:0043206 16 7 0,000 0,02778967 0,09286382 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02778967 0,09273502 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02778967 0,09260658 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02778967 0,0924785 ! lipoprotein transport GO:0042953 14 7 0,000 0,02778967 0,09235076 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02778967 0,09222338 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02778967 0,09209635 ! rhythmic behavior GO:0007622 15 7 0,000 0,02778967 0,09196967 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02778967 0,09184334 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02778967 0,09171736 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02778967 0,09159172 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02778967 0,09146642 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02778967 0,09134146 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02778967 0,09121685 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02778967 0,09109258 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02778967 0,09096864 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02778967 0,09084504 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02778967 0,09072178 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02778967 0,09059885 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02778967 0,09047625 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02778967 0,09035399 ! spinal cord patterning GO:0021511 13 7 0,000 0,02778967 0,09023205 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02778967 0,09011045 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02778967 0,08998917 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02778967 0,08986822 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02778967 0,08974759 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02778967 0,08962728 ! ovulation GO:0030728 9 7 0,000 0,02778967 0,0895073 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02778967 0,08938764 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02778967 0,08926829 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02778967 0,08914927 ! microtubule nucleation GO:0007020 20 7 0,000 0,02778967 0,08903056 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02778967 0,08891217 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02778967 0,08879409 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02778967 0,08867633 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02778967 0,08855888 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02778967 0,08844174 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02778967 0,0883249 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02778967 0,08820838 ! galactose metabolic process GO:0006012 13 7 0,000 0,02778967 0,08809216 ! vesicle fusion GO:0006906 17 7 0,000 0,02778967 0,08797625 ! response to dietary excess GO:0002021 8 7 0,000 0,02778967 0,08786065 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02778967 0,08774534 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02778967 0,08763034 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02778967 0,08751564 ! organ growth GO:0035265 15 7 0,000 0,02778967 0,08740124 ! purine salvage GO:0043101 10 7 0,000 0,02778967 0,08728714 ! nucleoside transport GO:0015858 8 7 0,000 0,02778967 0,08717334 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02778967 0,08705983 ! parturition GO:0007567 14 7 0,000 0,02778967 0,08694662 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02778967 0,0868337 ! rRNA modification GO:0000154 14 7 0,000 0,02778967 0,08672108 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02778967 0,08660875 ! spindle checkpoint GO:0031577 15 7 0,000 0,02778967 0,0864967 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02778967 0,08638495 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02778967 0,08627349 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02778967 0,08616231 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02778967 0,08605142 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02778967 0,08594081 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02778967 0,08583049 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02778967 0,08572045 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02778967 0,08561069 ! fibrinolysis GO:0042730 10 7 0,000 0,02778967 0,08550122 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02778967 0,08539202 ! eating behavior GO:0042755 7 7 0,000 0,02778967 0,0852831 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02778967 0,08517446 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02778967 0,0850661 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02778967 0,08495801 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02778967 0,08485019 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02778967 0,08474265 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02778967 0,08463538 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02778967 0,08452838 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02778967 0,08442166 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02778967 0,0843152 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02778967 0,08420901 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02778967 0,08410308 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02778967 0,08399743 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02778967 0,08389204 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02778967 0,08378691 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02778967 0,08368204 ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02778967 0,08357744 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02778967 0,0834731 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02778967 0,08336902 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02778967 0,0832652 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02778967 0,08316163 ! transcription termination GO:0006353 13 7 0,000 0,02778967 0,08305833 ! response to tumor cell GO:0002347 13 7 0,000 0,02778967 0,08295528 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02778967 0,08285248 ! anaphase GO:0051322 17 7 0,000 0,02778967 0,08274994 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02778967 0,08264765 ! axonal fasciculation GO:0007413 18 7 0,000 0,02778967 0,08254562 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02778967 0,08244384 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02778967 0,08234231 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02778967 0,08224102 ! diuresis GO:0030146 12 7 0,000 0,02778967 0,08213999 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02778967 0,08203921 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02778967 0,08193867 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02778967 0,08183837 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02778967 0,08173833 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02778967 0,08163853 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02778967 0,08153897 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02778967 0,08143965 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02778967 0,08134057 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02778967 0,08124174 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02778967 0,08114315 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02778967 0,08104479 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02778967 0,08094667 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02778967 0,08084879 ! lymph node development GO:0048535 10 7 0,000 0,02778967 0,08075115 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02778967 0,08065374 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02778967 0,08055657 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02778967 0,08045963 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02778967 0,08036292 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02778967 0,08026645 ! adult feeding behavior GO:0008343 9 7 0,000 0,02778967 0,08017021 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02778967 0,08007419 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02778967 0,07997841 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02778967 0,07988286 ! muscle adaptation GO:0043500 14 7 0,000 0,02778967 0,07978753 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02778967 0,07969243 ! retina homeostasis GO:0001895 12 7 0,000 0,02778967 0,07959756 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02778967 0,07950292 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02778967 0,07940849 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02778967 0,0793143 ! protein prenylation GO:0018342 18 7 0,000 0,02778967 0,07922032 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02778967 0,07912657 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02778967 0,07903304 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02778967 0,07893973 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,02986908 0,08474646 ! activation of MAPK activity GO:0000187 115 67 1,000 0,02986908 0,08464664 ! lung development GO:0030324 144 67 1,000 0,02986908 0,08454706 ! adaptive immune response GO:0002250 119 67 1,000 0,02986908 0,08444771 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,03069478 0,08668032 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,03069478 0,0865787 ! antigen processing and presentation GO:0019882 104 69 1,000 0,03152948 0,08882895 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0316966 0,08919533 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0316966 0,08909113 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,0316966 0,08898717 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0316966 0,08888346 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0316966 0,08877999 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0316966 0,08867675 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0316966 0,08857376 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0316966 0,08847101 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0316966 0,08836849 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0316966 0,08826621 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0316966 0,08816417 ! meiotic prophase I GO:0007128 13 8 0,000 0,0316966 0,08806237 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0316966 0,08796079 ! oligopeptide transport GO:0006857 15 8 0,000 0,0316966 0,08785946 ! UTP metabolic process GO:0046051 8 8 0,000 0,0316966 0,08775835 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0316966 0,08765748 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0316966 0,08755684 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0316966 0,08745643 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0316966 0,08735625 ! succinate metabolic process GO:0006105 14 8 0,000 0,0316966 0,0872563 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0316966 0,08715658 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0316966 0,08705709 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0316966 0,08695782 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0316966 0,08685878 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0316966 0,08675996 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0316966 0,08666137 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0316966 0,08656301 ! reflex GO:0060004 16 8 0,000 0,0316966 0,08646486 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0316966 0,08636694 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0316966 0,08626924 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0316966 0,08617176 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0316966 0,0860745 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0316966 0,08597746 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0316966 0,08588064 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0316966 0,08578404 ! pigment granule organization GO:0048753 16 8 0,000 0,0316966 0,08568765 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0316966 0,08559148 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0316966 0,08549553 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0316966 0,08539979 ! histidine metabolic process GO:0006547 16 8 0,000 0,0316966 0,08530426 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0316966 0,08520895 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0316966 0,08511385 ! glycine catabolic process GO:0006546 13 8 0,000 0,0316966 0,08501896 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0316966 0,08492429 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0316966 0,08482982 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0316966 0,08473557 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0316966 0,08464152 ! melanin metabolic process GO:0006582 15 8 0,000 0,0316966 0,08454768 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0316966 0,08445405 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0316966 0,08436063 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0316966 0,08426741 ! macrophage activation GO:0042116 12 8 0,000 0,0316966 0,0841744 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0316966 0,0840816 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0316966 0,083989 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0316966 0,0838966 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0316966 0,08380441 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0316966 0,08371241 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0316966 0,08362062 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0316966 0,08352903 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0316966 0,08343765 ! osteoblast development GO:0002076 16 8 0,000 0,0316966 0,08334646 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0316966 0,08325547 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0316966 0,08316468 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0316966 0,08307408 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0316966 0,08298369 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0316966 0,08289349 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0316966 0,08280348 ! response to UV-B GO:0010224 16 8 0,000 0,0316966 0,08271368 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0316966 0,08262406 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0316966 0,08253464 ! intermediate filament organization GO:0045109 12 8 0,000 0,0316966 0,08244541 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0316966 0,08235638 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0316966 0,08226754 ! cellular extravasation GO:0045123 12 8 0,000 0,0316966 0,08217889 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0316966 0,08209043 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0316966 0,08200216 ! response to antibiotic GO:0046677 11 8 0,000 0,0316966 0,08191408 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0316966 0,08182619 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0316966 0,08173849 ! DNA topological change GO:0006265 12 8 0,000 0,0316966 0,08165097 ! response to tropane GO:0014073 15 8 0,000 0,0316966 0,08156365 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0316966 0,08147651 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0316966 0,08138955 ! melanosome transport GO:0032402 13 8 0,000 0,0316966 0,08130278 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0316966 0,0812162 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0316966 0,0811298 ! mast cell activation GO:0045576 14 8 0,000 0,0316966 0,08104358 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0316966 0,08095755 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0316966 0,0808717 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0316966 0,08078603 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0316966 0,08070054 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0316966 0,08061523 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0316966 0,0805301 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0316966 0,08044516 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0316966 0,08036039 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0316966 0,0802758 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0316966 0,08019139 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0316966 0,08010715 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0316966 0,08002309 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0316966 0,07993921 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0316966 0,07985551 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0316966 0,07977198 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0316966 0,07968862 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0316966 0,07960544 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0316966 0,07952243 ! hormone catabolic process GO:0042447 17 8 0,000 0,0316966 0,07943959 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0316966 0,07935693 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0316966 0,07927444 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0316966 0,07919212 ! ATP catabolic process GO:0006200 11 8 0,000 0,0316966 0,07910997 ! blastocyst growth GO:0001832 19 8 0,000 0,0316966 0,07902799 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0316966 0,07894618 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0316966 0,07886454 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0316966 0,07878307 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0316966 0,07870176 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0316966 0,07862063 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0316966 0,07853966 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0316966 0,07845886 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0316966 0,07837822 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0316966 0,07829775 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0316966 0,07821744 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0316966 0,0781373 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0316966 0,07805733 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0316966 0,07797751 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0316966 0,07789786 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0316966 0,07781838 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0316966 0,07773905 ! respiratory tube development GO:0030323 150 70 1,000 0,0323731 0,0793174 ! humoral immune response GO:0006959 109 71 1,000 0,03322556 0,0813232 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03408678 0,08334632 ! carbohydrate transport GO:0008643 110 72 1,000 0,03408678 0,08326171 ! respiratory system development GO:0060541 153 72 1,000 0,03408678 0,08317726 ! axon extension GO:0048675 15 9 0,000 0,03558795 0,08675238 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03558795 0,08666458 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03558795 0,08657695 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03558795 0,0864895 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03558795 0,08640222 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03558795 0,08631512 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03558795 0,0862282 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03558795 0,08614145 ! phosphate transport GO:0006817 19 9 0,000 0,03558795 0,08605488 ! reproductive behavior GO:0019098 19 9 0,000 0,03558795 0,08596848 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03558795 0,08588225 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03558795 0,08579619 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03558795 0,08571031 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03558795 0,0856246 ! GTP metabolic process GO:0046039 9 9 0,000 0,03558795 0,08553906 ! RNA methylation GO:0001510 15 9 0,000 0,03558795 0,08545369 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03558795 0,0853685 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03558795 0,08528347 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03558795 0,08519861 ! artery development GO:0060840 24 9 0,000 0,03558795 0,08511392 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03558795 0,0850294 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03558795 0,08494504 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03558795 0,08486085 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03558795 0,08477683 ! chemosensory behavior GO:0007635 20 9 0,000 0,03558795 0,08469298 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03558795 0,08460929 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03558795 0,08452577 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03558795 0,08444241 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03558795 0,08435921 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03558795 0,08427618 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03558795 0,08419331 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03558795 0,08411061 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03558795 0,08402807 ! protein targeting to ER GO:0045047 22 9 0,000 0,03558795 0,08394569 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03558795 0,08386347 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03558795 0,08378141 ! T cell selection GO:0045058 23 9 0,000 0,03558795 0,08369951 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03558795 0,08361777 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03558795 0,0835362 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03558795 0,08345478 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03558795 0,08337352 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03558795 0,08329241 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03558795 0,08321147 ! mannose metabolic process GO:0006013 13 9 0,000 0,03558795 0,08313068 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03558795 0,08305005 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03558795 0,08296957 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03558795 0,08288926 ! receptor clustering GO:0043113 18 9 0,000 0,03558795 0,08280909 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03558795 0,08272908 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03558795 0,08264923 ! ruffle organization GO:0031529 15 9 0,000 0,03558795 0,08256953 ! retinol metabolic process GO:0042572 18 9 0,000 0,03558795 0,08248998 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03558795 0,08241059 ! behavioral fear response GO:0001662 22 9 0,000 0,03558795 0,08233135 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03558795 0,08225226 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03558795 0,08217332 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03558795 0,08209454 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03558795 0,0820159 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03558795 0,08193742 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03558795 0,08185908 ! segment specification GO:0007379 13 9 0,000 0,03558795 0,0817809 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03558795 0,08170286 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03558795 0,08162498 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03558795 0,08154724 ! response to amine stimulus GO:0014075 13 9 0,000 0,03558795 0,08146965 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03558795 0,08139221 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03558795 0,08131491 ! erythrocyte development GO:0048821 15 9 0,000 0,03558795 0,08123776 ! gas homeostasis GO:0033483 16 9 0,000 0,03558795 0,08116076 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03558795 0,0810839 ! renal water homeostasis GO:0003091 14 9 0,000 0,03558795 0,08100719 ! postreplication repair GO:0006301 22 9 0,000 0,03558795 0,08093063 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03558795 0,0808542 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03558795 0,08077793 ! icosanoid secretion GO:0032309 15 9 0,000 0,03558795 0,08070179 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03558795 0,0806258 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03558795 0,08054995 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03558795 0,08047425 ! regulation of cell division GO:0051302 15 9 0,000 0,03558795 0,08039869 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03558795 0,08032327 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03558795 0,08024799 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03558795 0,08017285 ! sterol catabolic process GO:0016127 11 9 0,000 0,03558795 0,08009785 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03558795 0,08002299 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03558795 0,07994827 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03558795 0,0798737 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03558795 0,07979926 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03558795 0,07972495 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03558795 0,07965079 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03558795 0,07957677 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03558795 0,07950288 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03558795 0,07942913 ! purine base metabolic process GO:0006144 21 9 0,000 0,03558795 0,07935552 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03558795 0,07928204 ! pigment granule transport GO:0051904 17 9 0,000 0,03558795 0,0792087 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03558795 0,07913549 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03558795 0,07906242 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03558795 0,07898948 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03558795 0,07891668 ! mitochondrion localization GO:0051646 15 9 0,000 0,03558795 0,07884402 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,03583513 0,07931861 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,03583513 0,07924571 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,03672211 0,0811326 ! rhythmic process GO:0048511 128 75 1,000 0,03672211 0,08105817 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,03761752 0,08295852 ! regulation of catabolic process GO:0009894 161 76 1,000 0,03761752 0,08288255 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,03852127 0,08479613 ! protein oligomerization GO:0051259 139 78 1,000 0,03943328 0,08672438 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03946379 0,08671222 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,03946379 0,0866331 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03946379 0,08655413 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03946379 0,0864753 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,03946379 0,08639661 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03946379 0,08631807 ! synapsis GO:0007129 13 10 0,000 0,03946379 0,08623967 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03946379 0,08616141 ! N-glycan processing GO:0006491 20 10 0,000 0,03946379 0,0860833 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03946379 0,08600532 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03946379 0,08592749 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03946379 0,0858498 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03946379 0,08577225 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03946379 0,08569484 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03946379 0,08561756 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03946379 0,08554043 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03946379 0,08546344 ! androgen metabolic process GO:0008209 17 10 0,000 0,03946379 0,08538658 ! phospholipid efflux GO:0033700 16 10 0,000 0,03946379 0,08530986 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03946379 0,08523328 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03946379 0,08515684 ! lung alveolus development GO:0048286 26 10 0,000 0,03946379 0,08508054 ! pathogenesis GO:0009405 13 10 0,000 0,03946379 0,08500437 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03946379 0,08492833 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03946379 0,08485244 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03946379 0,08477668 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03946379 0,08470105 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03946379 0,08462556 ! endoderm development GO:0007492 16 10 0,000 0,03946379 0,0845502 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03946379 0,08447498 ! arginine catabolic process GO:0006527 13 10 0,000 0,03946379 0,08439989 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03946379 0,08432494 ! proline metabolic process GO:0006560 13 10 0,000 0,03946379 0,08425011 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03946379 0,08417542 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03946379 0,08410087 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03946379 0,08402644 ! V(D)J recombination GO:0033151 28 10 0,000 0,03946379 0,08395215 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03946379 0,08387798 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03946379 0,08380395 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03946379 0,08373005 ! B cell proliferation GO:0042100 18 10 0,000 0,03946379 0,08365628 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03946379 0,08358264 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03946379 0,08350913 ! multicellular organism growth GO:0035264 18 10 0,000 0,03946379 0,08343574 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03946379 0,08336249 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03946379 0,08328937 ! epithelial cell development GO:0002064 20 10 0,000 0,03946379 0,08321637 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03946379 0,0831435 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03946379 0,08307076 ! macroautophagy GO:0016236 17 10 0,000 0,03946379 0,08299814 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03946379 0,08292566 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03946379 0,0828533 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03946379 0,08278106 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03946379 0,08270895 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,03946379 0,08263697 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03946379 0,08256511 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03946379 0,08249338 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03946379 0,08242177 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03946379 0,08235028 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03946379 0,08227892 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03946379 0,08220769 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03946379 0,08213657 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03946379 0,08206558 ! response to dsRNA GO:0043331 20 10 0,000 0,03946379 0,08199471 ! DNA ligation GO:0006266 19 10 0,000 0,03946379 0,08192397 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03946379 0,08185334 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03946379 0,08178284 ! melanosome localization GO:0032400 16 10 0,000 0,03946379 0,08171246 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03946379 0,0816422 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03946379 0,08157206 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03946379 0,08150204 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03946379 0,08143214 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03946379 0,08136236 ! mRNA cleavage GO:0006379 17 10 0,000 0,03946379 0,0812927 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03946379 0,08122316 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03946379 0,08115374 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03946379 0,08108444 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03946379 0,08101525 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03946379 0,08094619 ! salivary gland development GO:0007431 27 10 0,000 0,03946379 0,08087724 ! prophase GO:0051324 15 10 0,000 0,03946379 0,08080841 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03946379 0,08073969 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03946379 0,08067109 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03946379 0,08060261 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03946379 0,08053425 ! midbrain development GO:0030901 13 10 0,000 0,03946379 0,080466 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03946379 0,08039786 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03946379 0,08032985 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03946379 0,08026194 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03946379 0,08019415 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03946379 0,08012648 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03946379 0,08005892 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03946379 0,07999147 ! detection of calcium ion GO:0005513 23 10 0,000 0,03946379 0,07992414 ! oocyte development GO:0048599 17 10 0,000 0,03946379 0,07985692 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03946379 0,07978981 ! blastocyst formation GO:0001825 17 10 0,000 0,03946379 0,07972282 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03946379 0,07965594 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03946379 0,07958917 ! activation of innate immune response GO:0002218 12 10 0,000 0,03946379 0,07952251 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03946379 0,07945596 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03946379 0,07938953 ! response to nicotine GO:0035094 20 10 0,000 0,03946379 0,07932321 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03946379 0,07925699 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03946379 0,07919089 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03946379 0,0791249 ! localization within membrane GO:0051668 20 10 0,000 0,03946379 0,07905902 ! T cell activation GO:0042110 168 81 1,000 0,04221811 0,08450647 ! response to hypoxia GO:0001666 171 81 1,000 0,04221811 0,08443622 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,04221811 0,08436609 ! response to drug GO:0042493 143 82 1,000 0,04316239 0,0861815 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04332418 0,08643282 ! respiratory burst GO:0045730 17 11 0,000 0,04332418 0,08636121 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04332418 0,08628972 ! neuron fate specification GO:0048665 17 11 0,000 0,04332418 0,08621835 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04332418 0,0861471 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04332418 0,08607596 GO:0046579|positive regulation of Ras protein signal transduction, ! thyroid gland development GO:0030878 26 11 0,000 0,04332418 0,08600494 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04332418 0,08593404 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04332418 0,08586325 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04332418 0,08579258 ! response to pain GO:0048265 24 11 0,000 0,04332418 0,08572203 ! T cell proliferation GO:0042098 26 11 0,000 0,04332418 0,08565159 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04332418 0,08558127 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04332418 0,08551106 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04332418 0,08544097 ! bone resorption GO:0045453 16 11 0,000 0,04332418 0,085371 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04332418 0,08530113 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04332418 0,08523139 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04332418 0,08516175 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04332418 0,08509223 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04332418 0,08502283 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04332418 0,08495353 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04332418 0,08488435 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04332418 0,08481529 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04332418 0,08474633 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04332418 0,08467749 ! lipid digestion GO:0044241 18 11 0,000 0,04332418 0,08460875 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04332418 0,08454013 ! UV protection GO:0009650 19 11 0,000 0,04332418 0,08447163 ! adult heart development GO:0007512 14 11 0,000 0,04332418 0,08440323 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04332418 0,08433494 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04332418 0,08426676 ! temperature homeostasis GO:0001659 17 11 0,000 0,04332418 0,0841987 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04332418 0,08413074 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04332418 0,08406289 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04332418 0,08399515 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04332418 0,08392752 ! regulation of organ growth GO:0046620 13 11 0,000 0,04332418 0,08386 ! pigment granule localization GO:0051875 20 11 0,000 0,04332418 0,08379259 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04332418 0,08372529 ! vasoconstriction GO:0042310 18 11 0,000 0,04332418 0,08365809 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04332418 0,08359101 ! embryonic axis specification GO:0000578 18 11 0,000 0,04332418 0,08352403 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04332418 0,08345715 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04332418 0,08339039 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04332418 0,08332373 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04332418 0,08325718 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04332418 0,08319073 ! zymogen activation GO:0031638 15 11 0,000 0,04332418 0,08312439 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04332418 0,08305816 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04332418 0,08299203 ! nucleosome positioning GO:0016584 15 11 0,000 0,04332418 0,082926 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04332418 0,08286008 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04332418 0,08279427 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04332418 0,08272856 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04332418 0,08266295 ! acid secretion GO:0046717 18 11 0,000 0,04332418 0,08259745 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04332418 0,08253206 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04332418 0,08246676 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04332418 0,08240157 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04332418 0,08233648 ! oocyte differentiation GO:0009994 18 11 0,000 0,04332418 0,0822715 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04332418 0,08220661 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04332418 0,08214183 ! cholesterol efflux GO:0033344 19 11 0,000 0,04332418 0,08207715 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04332418 0,08201258 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04332418 0,0819481 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04332418 0,08188373 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04332418 0,08181946 ! embryonic gut development GO:0048566 15 11 0,000 0,04332418 0,08175528 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04332418 0,08169121 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04332418 0,08162724 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04332418 0,08156337 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04332418 0,0814996 ! defense response to fungus GO:0050832 13 11 0,000 0,04332418 0,08143593 ! developmental induction GO:0031128 19 11 0,000 0,04332418 0,08137235 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04332418 0,08130888 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04332418 0,08124551 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04332418 0,08118223 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04332418 0,08111906 ! response to oxygen levels GO:0070482 176 83 1,000 0,04411454 0,08253466 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,04604214 0,08607411 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04716919 0,08811263 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04716919 0,08804428 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04716919 0,08797602 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,04716919 0,08790788 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04716919 0,08783984 ! cartilage condensation GO:0001502 20 12 0,000 0,04716919 0,0877719 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04716919 0,08770407 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04716919 0,08763635 ! protein complex disassembly GO:0043241 27 12 0,000 0,04716919 0,08756873 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04716919 0,08750121 ! hippocampus development GO:0021766 26 12 0,000 0,04716919 0,0874338 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04716919 0,08736649 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04716919 0,08729929 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04716919 0,08723218 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,04716919 0,08716519 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04716919 0,08709829 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04716919 0,0870315 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04716919 0,08696481 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04716919 0,08689822 ! drug transport GO:0015893 16 12 0,000 0,04716919 0,08683173 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04716919 0,08676535 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04716919 0,08669906 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04716919 0,08663288 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04716919 0,0865668 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04716919 0,08650082 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04716919 0,08643494 ! forebrain cell migration GO:0021885 21 12 0,000 0,04716919 0,08636916 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04716919 0,08630348 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04716919 0,0862379 ! fear response GO:0042596 26 12 0,000 0,04716919 0,08617242 ! monoamine transport GO:0015844 18 12 0,000 0,04716919 0,08610703 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04716919 0,08604175 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04716919 0,08597657 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04716919 0,08591149 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04716919 0,0858465 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04716919 0,08578161 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04716919 0,08571682 ! protein homotetramerization GO:0051289 21 12 0,000 0,04716919 0,08565213 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04716919 0,08558754 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04716919 0,08552304 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04716919 0,08545864 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04716919 0,08539434 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04716919 0,08533013 ! cranial nerve development GO:0021545 20 12 0,000 0,04716919 0,08526602 ! fucose catabolic process GO:0019317 22 12 0,000 0,04716919 0,08520201 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04716919 0,08513809 ! histone methylation GO:0016571 26 12 0,000 0,04716919 0,08507427 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04716919 0,08501054 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04716919 0,08494691 ! gland morphogenesis GO:0022612 29 12 0,000 0,04716919 0,08488337 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04716919 0,08481993 ! T cell homeostasis GO:0043029 25 12 0,000 0,04716919 0,08475659 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04716919 0,08469334 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04716919 0,08463018 ! spleen development GO:0048536 22 12 0,000 0,04716919 0,08456712 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04716919 0,08450415 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04716919 0,08444127 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04716919 0,08437849 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04716919 0,0843158 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04716919 0,08425321 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04716919 0,08419071 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04716919 0,0841283 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04716919 0,08406598 ! response to cold GO:0009409 17 12 0,000 0,04716919 0,08400375 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04716919 0,08394162 ! regulation of protein transport GO:0051223 154 87 1,000 0,04800029 0,08535751 GO:0070201|regulation of establishment of protein localization, ! regulation of cell cycle process GO:0010564 149 90 1,000 0,05099351 0,09061328 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05099887 0,09055593 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05099887 0,09048915 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05099887 0,09042246 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05099887 0,09035588 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05099887 0,09028939 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05099887 0,090223 ! lipid localization GO:0010876 28 13 0,000 0,05099887 0,09015671 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05099887 0,09009052 ! organelle fusion GO:0048284 32 13 0,000 0,05099887 0,09002442 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05099887 0,08995842 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05099887 0,08989252 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05099887 0,08982671 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05099887 0,089761 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05099887 0,08969538 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05099887 0,08962986 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05099887 0,08956444 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05099887 0,08949911 ! methionine metabolic process GO:0006555 27 13 0,000 0,05099887 0,08943388 ! plasma membrane organization GO:0007009 24 13 0,000 0,05099887 0,08936874 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05099887 0,0893037 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05099887 0,08923875 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05099887 0,0891739 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05099887 0,08910914 ! response to X-ray GO:0010165 25 13 0,000 0,05099887 0,08904447 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05099887 0,0889799 ! exocrine system development GO:0035272 32 13 0,000 0,05099887 0,08891542 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05099887 0,08885104 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05099887 0,08878675 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05099887 0,08872255 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05099887 0,08865844 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05099887 0,08859443 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05099887 0,08853051 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05099887 0,08846668 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05099887 0,08840294 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05099887 0,0883393 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05099887 0,08827574 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05099887 0,08821228 ! ribosome assembly GO:0042255 17 13 0,000 0,05099887 0,08814891 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,05099887 0,08808563 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05099887 0,08802244 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05099887 0,08795934 ! chromatin silencing GO:0006342 26 13 0,000 0,05099887 0,08789633 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05099887 0,08783342 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05099887 0,08777059 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05099887 0,08770785 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05099887 0,0876452 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05099887 0,08758264 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05099887 0,08752017 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05099887 0,08745779 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05099887 0,0873955 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05099887 0,0873333 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05099887 0,08727118 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05099887 0,08720916 ! embryonic placenta development GO:0001892 23 13 0,000 0,05099887 0,08714722 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05099887 0,08708537 ! insulin secretion GO:0030073 23 13 0,000 0,05099887 0,0870236 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05099887 0,08696193 ! acrosome reaction GO:0007340 18 13 0,000 0,05099887 0,08690034 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,05405211 0,09203778 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,05405211 0,09197269 ! regulation of membrane potential GO:0042391 164 93 1,000 0,05405211 0,09190769 ! rRNA transcription GO:0009303 25 14 0,000 0,05481329 0,09313613 ! lactation GO:0007595 26 14 0,000 0,05481329 0,09307041 ! reproductive cellular process GO:0048610 20 14 0,000 0,05481329 0,09300477 ! tRNA modification GO:0006400 20 14 0,000 0,05481329 0,09293923 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05481329 0,09287378 ! regulation of S phase GO:0033261 23 14 0,000 0,05481329 0,09280842 ! water transport GO:0006833 21 14 0,000 0,05481329 0,09274315 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05481329 0,09267798 ! non-recombinational repair GO:0000726 25 14 0,000 0,05481329 0,0926129 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05481329 0,0925479 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05481329 0,092483 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05481329 0,0924182 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05481329 0,09235348 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05481329 0,09228885 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05481329 0,09222431 ! palate development GO:0060021 31 14 0,000 0,05481329 0,09215986 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05481329 0,09209551 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05481329 0,09203124 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05481329 0,09196706 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05481329 0,09190297 ! arginine metabolic process GO:0006525 17 14 0,000 0,05481329 0,09183897 ! regulation of heart rate GO:0002027 24 14 0,000 0,05481329 0,09177506 ! organic alcohol transport GO:0015850 29 14 0,000 0,05481329 0,09171124 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05481329 0,09164751 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05481329 0,09158386 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05481329 0,09152031 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05481329 0,09145684 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05481329 0,09139346 ! L-amino acid transport GO:0015807 30 14 0,000 0,05481329 0,09133017 ! bone mineralization GO:0030282 17 14 0,000 0,05481329 0,09126697 ! stem cell development GO:0048864 43 14 0,000 0,05481329 0,09120385 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05481329 0,09114082 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05481329 0,09107788 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05481329 0,09101502 ! cerebellum development GO:0021549 21 14 0,000 0,05481329 0,09095225 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05481329 0,09088957 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05481329 0,09082697 ! response to gamma radiation GO:0010332 28 14 0,000 0,05481329 0,09076446 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05481329 0,09070204 ! cofactor transport GO:0051181 26 14 0,000 0,05481329 0,0906397 ! NADP metabolic process GO:0006739 24 14 0,000 0,05481329 0,09057745 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05481329 0,09051528 ! intestinal absorption GO:0050892 25 14 0,000 0,05481329 0,0904532 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05481329 0,0903912 ! oxygen transport GO:0015671 21 14 0,000 0,05481329 0,09032929 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05481329 0,09026746 ! male genitalia development GO:0030539 24 14 0,000 0,05481329 0,09020572 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05481329 0,09014406 ! regulation of axon extension GO:0030516 37 14 0,000 0,05481329 0,09008249 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05481329 0,090021 ! transcription initiation GO:0006352 153 94 1,000 0,05508584 0,0904069 ! forebrain development GO:0030900 188 95 1,000 0,05612653 0,09205211 ! detection of stimulus GO:0051606 151 96 1,000 0,05717413 0,09370638 ! regulation of protein localization GO:0032880 176 97 1,000 0,05822856 0,09536959 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05861249 0,0959331 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05861249 0,09586789 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05861249 0,09580276 ! superoxide anion generation GO:0042554 20 15 0,000 0,05861249 0,09573772 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,05861249 0,09567277 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05861249 0,09560791 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05861249 0,09554313 ! copper ion transport GO:0006825 20 15 0,000 0,05861249 0,09547844 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05861249 0,09541384 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05861249 0,09534933 ! sulfate transport GO:0008272 23 15 0,000 0,05861249 0,09528491 ! response to cAMP GO:0051591 22 15 0,000 0,05861249 0,09522057 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05861249 0,09515632 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05861249 0,09509215 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05861249 0,09502807 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05861249 0,09496408 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05861249 0,09490018 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05861249 0,09483636 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05861249 0,09477262 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05861249 0,09470897 ! vesicle coating GO:0006901 33 15 0,000 0,05861249 0,09464541 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05861249 0,09458193 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05861249 0,09451854 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,05861249 0,09445523 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05861249 0,09439201 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,05861249 0,09432887 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05861249 0,09426582 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05861249 0,09420285 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05861249 0,09413996 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05861249 0,09407716 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05861249 0,09401444 ! histone deacetylation GO:0016575 20 15 0,000 0,05861249 0,09395181 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05861249 0,09388926 ! tissue regeneration GO:0042246 26 15 0,000 0,05861249 0,09382679 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05861249 0,0937644 ! water homeostasis GO:0030104 27 15 0,000 0,05861249 0,0937021 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05861249 0,09363988 ! muscle maintenance GO:0046716 26 15 0,000 0,05861249 0,09357774 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05861249 0,09351569 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05861249 0,09345372 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05861249 0,09339183 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05861249 0,09333002 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05861249 0,09326829 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05861249 0,09320665 ! detection of bacterium GO:0016045 18 15 0,000 0,05861249 0,09314509 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,05861249 0,09308361 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05861249 0,0930222 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05861249 0,09296088 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05861249 0,09289965 ! peptide hormone processing GO:0016486 23 15 0,000 0,05861249 0,09283849 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,06035764 0,09553979 GO:0060538|skeletal muscle organ development, ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06239656 0,09870225 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06239656 0,0986374 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06239656 0,09857263 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06239656 0,09850795 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06239656 0,09844336 ! bone remodeling GO:0046849 27 16 0,000 0,06239656 0,09837885 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06239656 0,09831442 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06239656 0,09825008 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06239656 0,09818582 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06239656 0,09812165 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06239656 0,09805756 ! startle response GO:0001964 28 16 0,000 0,06239656 0,09799355 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06239656 0,09792963 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06239656 0,09786579 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06239656 0,09780203 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06239656 0,09773836 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06239656 0,09767477 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06239656 0,09761126 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06239656 0,09754784 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06239656 0,09748449 ! response to osmotic stress GO:0006970 25 16 0,000 0,06239656 0,09742123 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06239656 0,09735805 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06239656 0,09729496 ! fructose metabolic process GO:0006000 25 16 0,000 0,06239656 0,09723194 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06239656 0,09716901 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06239656 0,09710616 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06239656 0,09704339 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06239656 0,0969807 ! axon cargo transport GO:0008088 43 16 0,000 0,06239656 0,09691809 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06239656 0,09685556 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06239656 0,09679311 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06239656 0,09673075 ! DNA replication initiation GO:0006270 27 16 0,000 0,06239656 0,09666846 ! neuron recognition GO:0008038 35 16 0,000 0,06239656 0,09660625 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06239656 0,09654413 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06239656 0,09648208 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06239656 0,09642012 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06239656 0,09635823 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06239656 0,09629642 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06239656 0,09623469 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06239656 0,09617304 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06239656 0,09611147 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06239656 0,09604998 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06239656 0,09598857 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06239656 0,09592723 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06239656 0,09586598 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06239656 0,0958048 ! defense response to virus GO:0051607 37 16 0,000 0,06239656 0,0957437 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06616554 0,10146226 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06616554 0,10139763 ! metencephalon development GO:0022037 30 17 0,000 0,06616554 0,10133309 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06616554 0,10126863 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06616554 0,10120425 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06616554 0,10113995 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06616554 0,10107573 ! signal complex assembly GO:0007172 41 17 0,000 0,06616554 0,1010116 ! endothelial cell migration GO:0043542 28 17 0,000 0,06616554 0,10094755 ! inositol metabolic process GO:0006020 28 17 0,000 0,06616554 0,10088357 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06616554 0,10081968 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06616554 0,10075587 ! glial cell development GO:0021782 27 17 0,000 0,06616554 0,10069214 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06616554 0,1006285 ! adult walking behavior GO:0007628 33 17 0,000 0,06616554 0,10056493 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06616554 0,10050144 ! heart looping GO:0001947 30 17 0,000 0,06616554 0,10043803 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06616554 0,1003747 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06616554 0,10031146 ! myoblast differentiation GO:0045445 45 17 0,000 0,06616554 0,10024829 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06616554 0,1001852 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06616554 0,10012219 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06616554 0,10005926 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06616554 0,09999641 ! glycine metabolic process GO:0006544 28 17 0,000 0,06616554 0,09993364 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06616554 0,09987094 ! NAD metabolic process GO:0019674 29 17 0,000 0,06616554 0,09980833 ! membrane budding GO:0006900 37 17 0,000 0,06616554 0,09974579 ! DNA integration GO:0015074 29 17 0,000 0,06616554 0,09968333 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06616554 0,09962095 ! regulation of protein binding GO:0043393 33 17 0,000 0,06616554 0,09955865 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06616554 0,09949643 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06616554 0,09943428 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06616554 0,09937221 ! genitalia development GO:0048806 30 17 0,000 0,06616554 0,09931022 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06616554 0,0992483 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06616554 0,09918647 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06616554 0,09912471 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06616554 0,09906302 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06616554 0,09900142 ! steroid catabolic process GO:0006706 31 17 0,000 0,06616554 0,09893989 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06616554 0,09887844 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06616554 0,09881706 ! gas transport GO:0015669 25 17 0,000 0,06616554 0,09875576 ! organic cation transport GO:0015695 31 17 0,000 0,06616554 0,09869453 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06616554 0,09863338 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06616554 0,09857231 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06616554 0,09851131 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06616554 0,09845039 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06991949 0,10397175 ! neuron maturation GO:0042551 42 18 0,000 0,06991949 0,10390753 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06991949 0,10384339 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06991949 0,10377933 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06991949 0,10371535 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06991949 0,10365144 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06991949 0,10358762 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06991949 0,10352387 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06991949 0,1034602 ! centrosome cycle GO:0007098 25 18 0,000 0,06991949 0,10339661 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06991949 0,1033331 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06991949 0,10326967 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06991949 0,10320631 ! response to retinoic acid GO:0032526 26 18 0,000 0,06991949 0,10314304 ! response to fungus GO:0009620 21 18 0,000 0,06991949 0,10307983 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06991949 0,10301671 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06991949 0,10295367 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06991949 0,1028907 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06991949 0,10282781 ! vitamin transport GO:0051180 27 18 0,000 0,06991949 0,10276499 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06991949 0,10270225 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06991949 0,10263959 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06991949 0,10257701 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06991949 0,1025145 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06991949 0,10245206 ! nerve development GO:0021675 28 18 0,000 0,06991949 0,10238971 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06991949 0,10232743 ! protein secretion GO:0009306 39 19 0,000 0,07365848 0,10773392 ! positive regulation of translation GO:0045727 30 19 0,000 0,07365848 0,10766846 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07365848 0,10760309 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07365848 0,1075378 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,07365848 0,10747258 ! skin development GO:0043588 36 19 0,000 0,07365848 0,10740745 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07365848 0,10734239 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07365848 0,10727742 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07365848 0,10721252 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07365848 0,1071477 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07365848 0,10708296 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07365848 0,10701829 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,07365848 0,10695371 ! cerebral cortex development GO:0021987 36 19 0,000 0,07365848 0,1068892 ! pigmentation during development GO:0048066 41 19 0,000 0,07365848 0,10682477 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,07365848 0,10676042 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,07365848 0,10669614 ! heme metabolic process GO:0042168 36 19 0,000 0,07365848 0,10663194 ! neuromuscular junction development GO:0007528 34 19 0,000 0,07365848 0,10656782 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07365848 0,10650378 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,07365848 0,10643981 ! heart process GO:0003015 30 19 0,000 0,07365848 0,10637593 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07365848 0,10631211 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07365848 0,10624838 ! visual learning GO:0008542 36 19 0,000 0,07365848 0,10618472 ! G1 phase GO:0051318 40 19 0,000 0,07365848 0,10612113 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07365848 0,10605762 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07365848 0,10599419 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07365848 0,10593084 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07365848 0,10586756 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07365848 0,10580435 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07365848 0,10574122 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07365848 0,10567817 ! cilium assembly GO:0042384 37 19 0,000 0,07365848 0,10561519 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07365848 0,10555229 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07738255 0,11082287 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,07738255 0,11075695 ! positive regulation of ossification GO:0045778 47 20 0,000 0,07738255 0,1106911 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07738255 0,11062533 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,07738255 0,11055963 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07738255 0,11049402 ! response to vitamin GO:0033273 31 20 0,000 0,07738255 0,11042848 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,07738255 0,11036303 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,07738255 0,11029765 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07738255 0,11023234 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07738255 0,11016712 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,07738255 0,11010197 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07738255 0,11003689 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07738255 0,1099719 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,07738255 0,10990698 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,07738255 0,10984214 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07738255 0,10977737 ! body fluid secretion GO:0007589 31 20 0,000 0,07738255 0,10971268 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07738255 0,10964807 ! peptide secretion GO:0002790 35 20 0,000 0,07738255 0,10958353 ! stem cell differentiation GO:0048863 53 20 0,000 0,07738255 0,10951907 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07738255 0,10945469 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07738255 0,10939038 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,07738255 0,10932614 ! sensory perception of pain GO:0019233 30 20 0,000 0,07738255 0,10926199 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07738255 0,1091979 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07738255 0,10913389 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,07738255 0,10906996 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,07738255 0,1090061 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07738255 0,10894232 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,07738255 0,10887861 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07738255 0,10881498 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07738255 0,10875142 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07738255 0,10868793 ! regulation of glucose import GO:0046324 29 20 0,000 0,07738255 0,10862452 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07738255 0,10856118 ! actin filament-based movement GO:0030048 43 20 0,000 0,07738255 0,10849792 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,07738255 0,10843473 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,07738255 0,10837161 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07738255 0,10830857 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07738255 0,1082456 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,07738255 0,1081827 ! regulation of cell killing GO:0031341 42 21 0,000 0,08109178 0,11330246 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08109178 0,1132367 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08109178 0,11317102 ! hormone secretion GO:0046879 38 21 0,000 0,08109178 0,11310541 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08109178 0,11303988 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08109178 0,11297443 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08109178 0,11290905 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08109178 0,11284374 ! axis specification GO:0009798 38 21 0,000 0,08109178 0,11277852 ! ovarian follicle development GO:0001541 35 21 0,000 0,08109178 0,11271336 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08109178 0,11264829 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08109178 0,11258329 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08109178 0,11251836 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08109178 0,11245351 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08109178 0,11238873 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08109178 0,11232403 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08109178 0,1122594 ! vasodilation GO:0042311 39 21 0,000 0,08109178 0,11219484 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08109178 0,11213036 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08109178 0,11206596 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08109178 0,11200163 ! oogenesis GO:0048477 36 21 0,000 0,08109178 0,11193737 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08109178 0,11187318 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,08109178 0,11180907 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08109178 0,11174504 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08109178 0,11168107 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08109178 0,11161718 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08109178 0,11155336 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08109178 0,11148962 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08109178 0,11142595 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08109178 0,11136235 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08109178 0,11129882 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08109178 0,11123537 ! collagen catabolic process GO:0030574 28 21 0,000 0,08109178 0,11117198 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08109178 0,11110868 ! gut development GO:0048565 39 21 0,000 0,08109178 0,11104544 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08478623 0,11603849 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,08478623 0,11597252 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08478623 0,11590662 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08478623 0,11584081 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08478623 0,11577506 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08478623 0,11570939 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08478623 0,1156438 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08478623 0,11557828 ! regeneration GO:0031099 41 22 0,000 0,08478623 0,11551283 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08478623 0,11544746 ! sensory perception of taste GO:0050909 28 22 0,000 0,08478623 0,11538216 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08478623 0,11531694 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,08478623 0,11525178 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08478623 0,11518671 ! vacuolar transport GO:0007034 36 22 0,000 0,08478623 0,1151217 ! lysosome organization GO:0007040 41 22 0,000 0,08478623 0,11505677 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08478623 0,11499192 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08478623 0,11492713 ! fucose metabolic process GO:0006004 39 22 0,000 0,08478623 0,11486242 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08478623 0,11479778 ! ureteric bud development GO:0001657 43 22 0,000 0,08478623 0,11473322 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08478623 0,11466872 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08478623 0,1146043 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08478623 0,11453995 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08478623 0,11447568 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08478623 0,11441147 ! sarcomere organization GO:0045214 30 22 0,000 0,08478623 0,11434734 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,08478623 0,11428328 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08478623 0,11421929 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08478623 0,11415538 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08478623 0,11409153 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08478623 0,11402776 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08478623 0,11396405 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,08846594 0,11884369 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,08846594 0,11877737 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,08846594 0,11871112 ! viral genome replication GO:0019079 41 23 0,000 0,08846594 0,11864495 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,08846594 0,11857885 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,08846594 0,11851283 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,08846594 0,11844688 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,08846594 0,118381 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,08846594 0,1183152 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,08846594 0,11824947 ! visual behavior GO:0007632 42 23 0,000 0,08846594 0,11818381 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,08846594 0,11811822 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,08846594 0,11805271 ! response to ethanol GO:0045471 46 23 0,000 0,08846594 0,11798727 ! peroxisome organization GO:0007031 37 23 0,000 0,08846594 0,11792191 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,08846594 0,11785661 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,08846594 0,11779139 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,08846594 0,11772624 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,08846594 0,11766116 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,08846594 0,11759615 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,08846594 0,11753122 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,08846594 0,11746636 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,08846594 0,11740157 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,08846594 0,11733685 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,08846594 0,1172722 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,08846594 0,11720762 ! fatty acid transport GO:0015908 44 23 0,000 0,08846594 0,11714312 ! platelet activation GO:0030168 37 23 0,000 0,08846594 0,11707868 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,08846594 0,11701432 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,08846594 0,11695002 ! hormone transport GO:0009914 40 23 0,000 0,08846594 0,1168858 ! cell-cell recognition GO:0009988 25 23 0,000 0,08846594 0,11682165 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,08846594 0,11675756 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,08846594 0,11669355 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,08846594 0,11662961 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,08846594 0,11656574 GO:0006099|tricarboxylic acid cycle, ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,09213097 0,12132847 ! positive regulation of fibroblast proliferation GO:0048146 43 24 0,000 0,09213097 0,1212621 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09213097 0,1211958 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09213097 0,12112957 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09213097 0,12106342 ! vesicle docking GO:0048278 47 24 0,000 0,09213097 0,12099734 ! spinal cord development GO:0021510 47 24 0,000 0,09213097 0,12093133 ! vacuole organization GO:0007033 43 24 0,000 0,09213097 0,12086539 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09213097 0,12079952 ! digestive system process GO:0022600 39 24 0,000 0,09213097 0,12073372 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09213097 0,120668 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,09213097 0,12060235 ! regulation of behavior GO:0050795 43 24 0,000 0,09213097 0,12053677 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09213097 0,12047126 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09213097 0,12040582 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09213097 0,12034046 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 47 24 0,000 0,09213097 0,12027516 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09213097 0,12020993 ! membrane depolarization GO:0051899 39 24 0,000 0,09213097 0,12014478 ! pallium development GO:0021543 49 24 0,000 0,09213097 0,1200797 ! pentose metabolic process GO:0019321 35 24 0,000 0,09213097 0,12001468 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,09213097 0,11994974 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,09213097 0,11988487 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09213097 0,11982006 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09213097 0,11975533 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09213097 0,11969067 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09213097 0,11962608 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09213097 0,11956155 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09213097 0,1194971 ! regulation of amine transport GO:0051952 40 24 0,000 0,09213097 0,11943271 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,09578139 0,12409803 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,09578139 0,12403123 ! myelination GO:0042552 45 25 0,000 0,09578139 0,12396452 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09578139 0,12389787 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,09578139 0,12383129 ! phototransduction GO:0007602 33 25 0,000 0,09578139 0,12376479 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09578139 0,12369835 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,09578139 0,12363199 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,09578139 0,1235657 ! sperm motility GO:0030317 31 25 0,000 0,09578139 0,12349948 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,09578139 0,12343333 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,09578139 0,12336726 ! receptor metabolic process GO:0043112 46 25 0,000 0,09578139 0,12330125 ! chromosome condensation GO:0030261 45 25 0,000 0,09578139 0,12323531 ! response to starvation GO:0042594 42 25 0,000 0,09578139 0,12316945 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09578139 0,12310365 ! neural crest cell development GO:0014032 54 25 0,000 0,09578139 0,12303793 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09578139 0,12297227 ! negative regulation of cell development GO:0010721 73 25 0,000 0,09578139 0,12290669 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09578139 0,12284117 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09578139 0,12277572 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09578139 0,12271035 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09578139 0,12264504 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09578139 0,12257981 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09578139 0,12251464 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09578139 0,12244954 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09578139 0,12238451 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,09578139 0,12231955 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09578139 0,12225466 ! telomere organization GO:0032200 43 25 0,000 0,09578139 0,12218984 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09578139 0,12212508 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09578139 0,1220604 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09941726 0,12662675 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09941726 0,12655975 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09941726 0,12649282 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09941726 0,12642597 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09941726 0,12635918 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09941726 0,12629246 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09941726 0,12622582 ! molting cycle process GO:0022404 50 26 0,000 0,09941726 0,12615924 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,09941726 0,12609274 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09941726 0,1260263 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,09941726 0,12595994 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09941726 0,12589365 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09941726 0,12582742 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,09941726 0,12576126 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 0,000 0,09941726 0,12569518 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09941726 0,12562916 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09941726 0,12556322 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09941726 0,12549734 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09941726 0,12543153 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09941726 0,12536579 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09941726 0,12530012 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,09941726 0,12523452 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09941726 0,12516898 ! blastocyst development GO:0001824 49 26 0,000 0,09941726 0,12510352 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09941726 0,12503812 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09941726 0,12497279 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09941726 0,12490753 ! regulation of fibroblast proliferation GO:0048145 52 27 0,000 0,10303862 0,12938984 ! neuron fate commitment GO:0048663 48 27 0,000 0,10303862 0,12932234 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,10303862 0,12925492 ! iron ion transport GO:0006826 59 27 0,000 0,10303862 0,12918756 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10303862 0,12912028 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10303862 0,12905306 ! fat cell differentiation GO:0045444 50 27 0,000 0,10303862 0,12898592 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10303862 0,12891884 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,10303862 0,12885184 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10303862 0,1287849 ! autophagy GO:0006914 41 27 0,000 0,10303862 0,12871803 ! response to toxin GO:0009636 47 27 0,000 0,10303862 0,12865124 ! primary neural tube formation GO:0014020 51 27 0,000 0,10303862 0,12858451 ! base-excision repair GO:0006284 41 27 0,000 0,10303862 0,12851785 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10303862 0,12845126 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10303862 0,12838474 ! glutathione metabolic process GO:0006749 39 27 0,000 0,10303862 0,12831829 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10303862 0,1282519 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10303862 0,12818559 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,10303862 0,12811934 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10664555 0,13253574 ! circadian rhythm GO:0007623 50 28 0,000 0,10664555 0,13246732 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10664555 0,13239896 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10664555 0,13233068 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,10664555 0,13226247 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10664555 0,13219433 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10664555 0,13212626 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10664555 0,13205825 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,10664555 0,13199032 ! synaptogenesis GO:0007416 42 28 0,000 0,10664555 0,13192246 ! lipid oxidation GO:0034440 43 28 0,000 0,10664555 0,13185467 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10664555 0,13178695 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,10664555 0,1317193 ! translational initiation GO:0006413 65 29 0,000 0,11023809 0,13608663 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11023809 0,13601684 ! regulation of pH GO:0006885 43 29 0,000 0,11023809 0,13594712 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11023809 0,13587748 ! catechol metabolic process GO:0009712 54 29 0,000 0,11023809 0,1358079 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11023809 0,1357384 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,11023809 0,13566897 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,11023809 0,13559961 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,11023809 0,13553032 ! cell fate determination GO:0001709 60 29 0,000 0,11023809 0,1354611 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11023809 0,13539195 ! detection of light stimulus GO:0009583 38 29 0,000 0,11023809 0,13532288 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,11023809 0,13525387 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,11023809 0,13518493 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,11023809 0,13511607 ! tissue homeostasis GO:0001894 48 29 0,000 0,11023809 0,13504727 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,11023809 0,13497854 ! phenol metabolic process GO:0018958 55 30 0,000 0,1138163 0,13928892 ! zinc ion transport GO:0006829 45 30 0,000 0,1138163 0,1392181 ! membrane docking GO:0022406 61 30 0,000 0,1138163 0,13914736 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,1138163 0,13907669 ! regulation of innate immune response GO:0045088 51 30 0,000 0,1138163 0,1390061 ! myofibril assembly GO:0030239 47 30 0,000 0,1138163 0,13893557 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,1138163 0,13886512 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1138163 0,13879473 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,1138163 0,13872442 ! phospholipid transport GO:0015914 51 30 0,000 0,1138163 0,13865418 ! ensheathment of neurons GO:0007272 57 30 0,000 0,1138163 0,13858401 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1138163 0,13851392 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1138163 0,13844389 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,1138163 0,13837393 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,1138163 0,13830405 ! eye morphogenesis GO:0048592 60 30 0,000 0,1138163 0,13823423 ! regulation of B cell activation GO:0050864 50 30 0,000 0,1138163 0,13816449 ! response to heat GO:0009408 50 30 0,000 0,1138163 0,13809481 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11738024 0,1423472 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,11738024 0,14227549 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11738024 0,14220385 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11738024 0,14213228 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,11738024 0,14206079 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11738024 0,14198937 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11738024 0,14191801 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11738024 0,14184673 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,11738024 0,14177553 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11738024 0,14170439 ! peptide transport GO:0015833 55 31 0,000 0,11738024 0,14163332 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,11738024 0,14156233 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11738024 0,14149141 ! mesoderm formation GO:0001707 69 31 0,000 0,11738024 0,14142055 ! natural killer cell activation GO:0030101 45 31 0,000 0,11738024 0,14134977 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11738024 0,14127906 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11738024 0,14120842 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11738024 0,14113785 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,11738024 0,14106736 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11738024 0,14099693 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12092996 0,14518836 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12092996 0,14511595 ! cholesterol transport GO:0030301 56 32 0,000 0,12092996 0,14504361 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,12092996 0,14497134 ! spliceosome assembly GO:0000245 67 32 0,000 0,12092996 0,14489914 ! spindle organization GO:0007051 46 32 0,000 0,12092996 0,14482702 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12092996 0,14475497 ! metanephros development GO:0001656 74 32 0,000 0,12092996 0,14468299 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12092996 0,14461108 ! response to ionizing radiation GO:0010212 65 32 0,000 0,12092996 0,14453924 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,12092996 0,14446747 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,12092996 0,14439577 ! muscle cell development GO:0055001 49 32 0,000 0,12092996 0,14432415 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,12092996 0,14425259 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12092996 0,14418111 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,12092996 0,1441097 ! peripheral nervous system development GO:0007422 64 32 0,000 0,12092996 0,14403836 ! BMP signaling pathway GO:0030509 64 32 0,000 0,12092996 0,14396709 ! hindbrain development GO:0030902 61 32 0,000 0,12092996 0,14389589 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,12092996 0,14382476 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12092996 0,1437537 ! gene silencing GO:0016458 65 32 0,000 0,12092996 0,14368271 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,12446552 0,14781049 ! post-embryonic development GO:0009791 69 33 0,000 0,12446552 0,14773757 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,12446552 0,14766472 ! protein targeting to membrane GO:0006612 68 33 0,000 0,12446552 0,14759194 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,12446552 0,14751924 ! ceramide metabolic process GO:0006672 64 33 0,000 0,12446552 0,1474466 ! formation of primary germ layer GO:0001704 72 33 0,000 0,12446552 0,14737404 ! cell fate specification GO:0001708 52 33 0,000 0,12446552 0,14730155 ! sterol transport GO:0015918 57 33 0,000 0,12446552 0,14722913 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,12446552 0,14715678 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,12446552 0,14708451 ! adult locomotory behavior GO:0008344 59 33 0,000 0,12446552 0,1470123 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,12446552 0,14694016 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,12446552 0,1468681 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,12798699 0,15094936 ! glial cell differentiation GO:0010001 63 34 0,000 0,12798699 0,1508754 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12798699 0,15080151 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,12798699 0,1507277 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,12798699 0,15065396 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12798699 0,15058029 ! mismatch repair GO:0006298 46 34 0,000 0,12798699 0,15050669 ! spermatid development GO:0007286 63 34 0,000 0,12798699 0,15043317 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12798699 0,15035971 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12798699 0,15028633 ! placenta development GO:0001890 53 34 0,000 0,12798699 0,15021302 ! regulation of muscle development GO:0048634 70 35 0,000 0,1314944 0,15425428 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,1314944 0,15417911 ! negative regulation of secretion GO:0051048 63 35 0,000 0,1314944 0,15410401 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,1314944 0,15402898 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,1314944 0,15395403 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,1314944 0,15387915 ! odontogenesis GO:0042476 66 35 0,000 0,1314944 0,15380434 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,1314944 0,15372961 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,1314944 0,15365495 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,1314944 0,15358036 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,1314944 0,15350584 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,1314944 0,15343139 ! cytokine production GO:0001816 59 35 0,000 0,1314944 0,15335702 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,1314944 0,15328272 ! neural tube formation GO:0001841 67 35 0,000 0,1314944 0,15320849 ! vesicle localization GO:0051648 64 35 0,000 0,1314944 0,15313433 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,13498783 0,15712661 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,13498783 0,15705063 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,13498783 0,15697473 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,13498783 0,15689889 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,13498783 0,15682313 ! positive regulation of cell development GO:0010720 80 36 0,000 0,13498783 0,15674745 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,13498783 0,15667183 ! regulation of proteolysis GO:0030162 72 36 0,000 0,13498783 0,15659629 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,13498783 0,15652082 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,13498783 0,15644543 ! aerobic respiration GO:0009060 55 36 0,000 0,13498783 0,15637011 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,13498783 0,15629486 ! embryonic organ development GO:0048568 57 36 0,000 0,13498783 0,15621968 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,13498783 0,15614457 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13846731 0,16009244 ! meiosis I GO:0007127 65 37 0,000 0,13846731 0,16001554 ! sister chromatid segregation GO:0000819 58 37 0,000 0,13846731 0,15993872 ! actomyosin structure organization GO:0031032 62 37 0,000 0,13846731 0,15986198 ! organic anion transport GO:0015711 68 37 0,000 0,13846731 0,1597853 ! tissue remodeling GO:0048771 76 37 0,000 0,13846731 0,1597087 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,13846731 0,15963218 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,13846731 0,15955573 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13846731 0,15947935 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,13846731 0,15940304 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13846731 0,15932681 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,13846731 0,15925065 ! spermatid differentiation GO:0048515 66 37 0,000 0,13846731 0,15917456 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,14193292 0,16308052 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,14193292 0,16300268 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,14193292 0,16292491 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,14193292 0,16284721 ! lipid homeostasis GO:0055088 67 38 0,000 0,14193292 0,16276959 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,14193292 0,16269205 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,14193292 0,16261458 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,14193292 0,16253718 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,14193292 0,16245985 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,14193292 0,1623826 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,14193292 0,16230542 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1453847 0,16617368 ! mammary gland development GO:0030879 86 39 0,000 0,1453847 0,16609477 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1453847 0,16601594 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1453847 0,16593719 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1453847 0,16585851 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,1453847 0,1657799 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1453847 0,16570137 ! RNA modification GO:0009451 57 39 0,000 0,1453847 0,16562291 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1453847 0,16554453 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,14882271 0,16937911 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14882271 0,16929903 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14882271 0,16921902 ! negative regulation of binding GO:0051100 72 40 0,000 0,14882271 0,16913909 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,14882271 0,16905923 ! mesenchymal cell development GO:0014031 87 40 0,000 0,14882271 0,16897944 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14882271 0,16889974 ! cytokinesis GO:0000910 72 40 0,000 0,14882271 0,16882011 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,152247 0,17262313 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,152247 0,17254182 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,152247 0,17246059 ! gliogenesis GO:0042063 88 41 0,000 0,152247 0,17237943 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,152247 0,17229835 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,152247 0,17221734 ! T cell differentiation GO:0030217 81 41 0,000 0,152247 0,17213642 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,152247 0,17205556 ! female gamete generation GO:0007292 61 41 0,000 0,152247 0,17197478 ! polyol metabolic process GO:0019751 66 41 0,000 0,152247 0,17189408 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,152247 0,17181346 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,15565763 0,17558006 ! regulation of tube size GO:0035150 71 42 0,000 0,15565763 0,17549778 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,15565763 0,17541558 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,15565763 0,17533346 ! regulation of protein secretion GO:0050708 71 42 0,000 0,15565763 0,17525141 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,15905466 0,17899228 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15905466 0,1789086 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,15905466 0,178825 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,15905466 0,17874148 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,15905466 0,17865803 ! neural tube development GO:0021915 77 43 0,000 0,15905466 0,17857466 ! regulation of epithelial cell proliferation GO:0050678 111 43 0,000 0,15905466 0,17849137 ! striated muscle contraction GO:0006941 77 43 0,000 0,15905466 0,17840816 ! phagocytosis GO:0006909 90 43 0,000 0,15905466 0,17832502 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15905466 0,17824197 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,16243812 0,18194885 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,16243812 0,18186418 ! double-strand break repair GO:0006302 81 44 0,000 0,16243812 0,18177959 ! B cell differentiation GO:0030183 107 44 0,000 0,16243812 0,18169508 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,16243812 0,18161065 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,16243812 0,1815263 ! developmental growth GO:0048589 82 44 0,000 0,16243812 0,18144203 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,16580809 0,18512031 ! glycolysis GO:0006096 65 45 0,000 0,16580809 0,18503444 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,16580809 0,18494866 ! leukocyte migration GO:0050900 68 45 0,000 0,16580809 0,18486296 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,16580809 0,18477733 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,16580809 0,18469179 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,16580809 0,18460632 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,16580809 0,18452094 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,16580809 0,18443563 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,16580809 0,1843504 ! cell growth GO:0016049 84 45 0,000 0,16580809 0,18426525 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 0,000 0,16916461 0,18790861 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,16916461 0,18782189 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,16916461 0,18773526 ! positive regulation of defense response GO:0031349 76 47 0,000 0,17250773 0,19135712 ! response to calcium ion GO:0051592 81 47 0,000 0,17250773 0,19126894 ! endosome transport GO:0016197 108 47 0,000 0,17250773 0,19118084 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,17250773 0,19109282 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,17250773 0,19100488 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,17250773 0,19091702 ! JNK cascade GO:0007254 91 47 0,000 0,17250773 0,19082924 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,17250773 0,19074154 ! protein homooligomerization GO:0051260 76 47 0,000 0,17250773 0,19065393 ! mitochondrial transport GO:0006839 82 48 0,000 0,17583751 0,19424475 ! Notch signaling pathway GO:0007219 96 48 0,000 0,17583751 0,1941556 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,17583751 0,19406654 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,17583751 0,19397756 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,17583751 0,19388866 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,17583751 0,19379984 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,17583751 0,19371111 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,17583751 0,19362245 ! regulation of mast cell proliferation GO:0070666 81 48 0,000 0,17583751 0,19353388 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,17915401 0,19709398 ! regulation of action potential GO:0001508 95 49 0,000 0,17915401 0,1970039 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,17915401 0,19691391 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,17915401 0,19682399 ! regulation of ion transport GO:0043269 77 49 0,000 0,17915401 0,19673416 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,17915401 0,19664441 ! peptide metabolic process GO:0006518 76 49 0,000 0,17915401 0,19655474 ! response to temperature stimulus GO:0009266 76 49 0,000 0,17915401 0,19646515 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,17915401 0,19637565 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,17915401 0,19628622 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,17915401 0,19619688 ! neuromuscular process GO:0050905 99 50 0,000 0,18245727 0,19972347 ! regulation of ossification GO:0030278 117 50 0,000 0,18245727 0,19963264 ! inner ear development GO:0048839 79 50 0,000 0,18245727 0,1995419 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,18245727 0,19945124 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,18574734 0,20295554 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,18574734 0,20286341 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,18574734 0,20277137 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,18574734 0,20267941 ! chromatin remodeling GO:0006338 109 51 0,000 0,18574734 0,20258753 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,18574734 0,20249574 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,18574734 0,20240403 ! vesicle organization GO:0016050 107 51 0,000 0,18574734 0,2023124 ! regulation of leukocyte proliferation GO:0070663 88 51 0,000 0,18574734 0,20222086 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,18574734 0,2021294 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,18902428 0,20560236 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,18902428 0,20550946 ! membrane fusion GO:0006944 110 52 0,000 0,18902428 0,20541663 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,18902428 0,20532389 ! amino acid activation GO:0043038 92 52 0,000 0,18902428 0,20523124 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,18902428 0,20513867 ! synapse organization GO:0050808 85 52 0,000 0,18902428 0,20504618 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,19228815 0,20849269 ! RNA catabolic process GO:0006401 93 53 0,000 0,19228815 0,20839878 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,19228815 0,20830495 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,19228815 0,2082112 ! cell maturation GO:0048469 100 53 0,000 0,19228815 0,20811754 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,19228815 0,20802396 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,19228815 0,20793046 ! response to UV GO:0009411 104 53 0,000 0,19228815 0,20783705 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,19553898 0,21125586 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,19553898 0,21116104 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,19553898 0,21106631 ! cell recognition GO:0008037 85 54 0,000 0,19553898 0,21097166 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,19553898 0,21087709 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,19553898 0,21078261 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,19553898 0,21068822 ! chloride transport GO:0006821 90 55 0,000 0,19877684 0,21408106 ! glucose catabolic process GO:0006007 82 55 0,000 0,19877684 0,21398527 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,19877684 0,21388957 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,19877684 0,21379396 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,19877684 0,21369843 ! gastrulation GO:0007369 112 55 0,000 0,19877684 0,21360299 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,19877684 0,21350763 ! RNA elongation GO:0006354 79 55 0,000 0,19877684 0,21341235 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,19877684 0,21331717 ! sensory perception of smell GO:0007608 80 56 0,000 0,20200178 0,21668136 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,20200178 0,21658479 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,20200178 0,21648832 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,20200178 0,21639193 ! proton transport GO:0015992 94 56 0,000 0,20200178 0,21629563 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,20200178 0,21619941 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 0,000 0,20521384 0,21953957 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,20521384 0,219442 ! muscle fiber development GO:0048747 112 57 0,000 0,20521384 0,21934451 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,20521384 0,21924711 ! hydrogen transport GO:0006818 97 58 0,000 0,20841308 0,2225663 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,20841308 0,22246755 ! adult behavior GO:0030534 99 58 0,000 0,20841308 0,2223689 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,20841308 0,22227033 ! positive regulation of secretion GO:0051047 95 59 0,000 0,21159955 0,22556868 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,21159955 0,22546878 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,21159955 0,22536897 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,21477329 0,22864803 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,21477329 0,2285469 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,21477329 0,22844586 ! regulation of heart contraction GO:0008016 110 60 0,000 0,21477329 0,22834491 ! camera-type eye development GO:0043010 116 60 0,000 0,21477329 0,22824406 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,21477329 0,22814329 ! kidney development GO:0001822 122 60 0,000 0,21477329 0,2280426 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,21793437 0,23129691 ! mesoderm development GO:0007498 119 61 0,000 0,21793437 0,23119492 ! tRNA processing GO:0008033 89 61 0,000 0,21793437 0,23109303 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,21793437 0,23099123 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,22108282 0,23422513 ! regulation of mitosis GO:0007088 105 63 0,000 0,22421871 0,23744287 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,22421871 0,23733841 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,22421871 0,23723404 ! single fertilization GO:0007338 75 64 0,000 0,22734207 0,24043297 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,23045296 0,24361591 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,23045296 0,24350892 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,23045296 0,24340203 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,23355143 0,24656636 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,23355143 0,24645822 ! extracellular matrix organization GO:0030198 133 66 0,000 0,23355143 0,24635017 ! secondary metabolic process GO:0019748 116 66 0,000 0,23355143 0,24624222 ! developmental maturation GO:0021700 116 66 0,000 0,23355143 0,24613436 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,23663752 0,24927753 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,23663752 0,24916844 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,23663752 0,24905944 ! chromosome segregation GO:0007059 113 67 0,000 0,23663752 0,24895054 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,23663752 0,24884173 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,23663752 0,24873302 ! hexose catabolic process GO:0019320 104 67 0,000 0,23663752 0,2486244 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,23663752 0,24851588 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,23663752 0,24840745 ! amino acid transport GO:0006865 125 68 0,000 0,2397113 0,25152437 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,2397113 0,25141473 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,2397113 0,25130518 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,2397113 0,25119572 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,2397113 0,25108636 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,24277279 0,25418248 ! negative regulation of cell size GO:0045792 134 69 0,000 0,24277279 0,25407192 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,24277279 0,25396145 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,24277279 0,25385108 ! urogenital system development GO:0001655 137 69 0,000 0,24277279 0,25374081 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,24277279 0,25363063 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,24277279 0,25352055 ! appendage morphogenesis GO:0035107 135 70 0,000 0,24582206 0,25659344 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,24885916 0,25965097 ! appendage development GO:0048736 136 71 0,000 0,24885916 0,25953842 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 0,000 0,24885916 0,25942597 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,24885916 0,25931361 ! regulation of immune effector process GO:0002697 137 71 0,000 0,24885916 0,25920136 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,25188412 0,26223851 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,25188412 0,26212508 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,25188412 0,26201176 ! regulation of blood pressure GO:0008217 125 73 0,000 0,254897 0,2650312 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,254897 0,26491671 ! axon guidance GO:0007411 139 73 0,000 0,254897 0,26480233 ! fertilization GO:0009566 90 73 0,000 0,254897 0,26468804 ! transition metal ion transport GO:0000041 126 74 0,000 0,25789785 0,26768862 ! neurotransmitter transport GO:0006836 123 74 0,000 0,25789785 0,26757319 ! meiosis GO:0007126 121 74 0,000 0,25789785 0,26745786 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,25789785 0,26734262 ! eye development GO:0001654 143 74 0,000 0,25789785 0,26722749 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,26088671 0,2702081 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,26088671 0,27009184 ! meiotic cell cycle GO:0051321 122 75 0,000 0,26088671 0,26997567 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,26088671 0,2698596 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,26386363 0,27282162 ! defense response to bacterium GO:0042742 89 76 0,000 0,26386363 0,27270443 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,26386363 0,27258733 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,26682866 0,27553209 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,26682866 0,27541389 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,26682866 0,27529578 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,26978185 0,27822338 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,26978185 0,27810417 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,26978185 0,27798507 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,27272324 0,2808956 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,27272324 0,2807754 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,27272324 0,28065531 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,27272324 0,28053532 ! positive regulation of phosphorylation GO:0042327 129 79 0,000 0,27272324 0,28041543 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,27272324 0,28029565 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,27565288 0,28318567 ! response to metal ion GO:0010038 140 80 0,000 0,27565288 0,2830648 ! muscle cell differentiation GO:0042692 159 80 0,000 0,27565288 0,28294404 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,27565288 0,28282338 ! inorganic anion transport GO:0015698 138 80 0,000 0,27565288 0,28270283 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 0,000 0,27857081 0,28557366 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 0,000 0,27857081 0,28545204 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,27857081 0,28533051 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,28147709 0,28818463 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,28147709 0,28806205 ! response to nutrient GO:0007584 125 82 0,000 0,28147709 0,28793958 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,28147709 0,2878172 ! regulation of lyase activity GO:0051339 160 83 0,000 0,28437176 0,29065355 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,28725486 0,29347566 ! negative regulation of transport GO:0051051 153 84 0,000 0,28725486 0,2933511 ! negative regulation of growth GO:0045926 155 84 0,000 0,28725486 0,29322664 ! regulation of ligase activity GO:0051340 142 84 0,000 0,28725486 0,29310228 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,28725486 0,29297803 ! response to unfolded protein GO:0006986 131 85 0,000 0,29012644 0,29578144 ! nucleosome assembly GO:0006334 122 85 0,000 0,29012644 0,29565616 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,29012644 0,29553099 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,29298654 0,29831808 ! response to inorganic substance GO:0010035 153 86 0,000 0,29298654 0,29819189 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,29298654 0,2980658 ! chromatin assembly GO:0031497 124 86 0,000 0,29298654 0,29793982 ! tube morphogenesis GO:0035239 176 86 0,000 0,29298654 0,29781395 ! alcohol catabolic process GO:0046164 130 86 0,000 0,29298654 0,29768818 ! amine transport GO:0015837 155 86 0,000 0,29298654 0,29756252 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,29583522 0,30032892 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,29583522 0,30020225 ! cellular respiration GO:0045333 135 88 0,000 0,29867251 0,30295365 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,29867251 0,30282599 ! regulation of neurological system process GO:0031644 148 88 0,000 0,29867251 0,30269843 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,29867251 0,30257098 ! cellular defense response GO:0006968 114 89 0,000 0,30149847 0,30530527 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,30149847 0,30517683 ! ossification GO:0001503 188 90 0,000 0,30431313 0,3078963 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,30431313 0,30776687 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,30431313 0,30763756 ! bone development GO:0060348 189 91 0,000 0,30711655 0,3103412 ! sterol metabolic process GO:0016125 152 91 0,000 0,30711655 0,31021092 ! response to protein stimulus GO:0051789 149 91 0,000 0,30711655 0,31008074 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,30711655 0,30995067 ! regulation of defense response GO:0031347 149 92 0,000 0,30990876 0,31263751 ! nucleosome organization GO:0034728 138 92 0,000 0,30990876 0,31250648 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,30990876 0,31237556 ! vitamin metabolic process GO:0006766 139 92 0,000 0,30990876 0,31224475 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,31268981 0,31491489 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,31268981 0,31478313 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,31268981 0,31465147 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,31545974 0,31730608 ! female pregnancy GO:0007565 164 94 0,000 0,31545974 0,31717348 ! regulation of T cell activation GO:0050863 158 94 0,000 0,31545974 0,31704099 ! interphase of mitotic cell cycle GO:0051329 209 95 0,000 0,31821861 0,31968015 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,31821861 0,31954673 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,32096644 0,32217157 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,32370329 0,32478321 ! protein ubiquitination GO:0016567 217 97 0,000 0,32370329 0,32464782 ! hormone metabolic process GO:0042445 157 97 0,000 0,32370329 0,32451255 ! response to virus GO:0009615 160 98 0,000 0,32642921 0,32710898 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,32642921 0,3269728 ! interphase GO:0051325 213 98 0,000 0,32642921 0,32683673 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,32642921 0,32670078 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,32914422 0,32928108 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,32914422 0,32914422