pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/573-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 2,000 4,327E-07 1,057E-03 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 3,000 6,979E-07 8,525E-04 ! negative regulation of translation GO:0017148 32 20 3,000 6,979E-07 5,683E-04 ! nuclear migration GO:0007097 13 6 2,000 8,631E-07 5,272E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 8,631E-07 4,217E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of intracellular transport GO:0032388 42 22 3,000 1,048E-06 4,267E-04 ! adrenal gland development GO:0030325 17 7 2,000 1,507E-06 5,258E-04 ! male sex determination GO:0030238 15 7 2,000 1,507E-06 4,601E-04 ! sex determination GO:0007530 48 24 3,000 1,514E-06 4,11E-04 ! interaction with host GO:0051701 66 25 3,000 1,797E-06 4,391E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 2,404E-06 5,34E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 2,404E-06 4,895E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 2,48E-06 4,66E-04 ! macrophage differentiation GO:0030225 15 9 2,000 3,597E-06 6,277E-04 ! cell junction assembly GO:0034329 85 31 3,000 4,398E-06 7,163E-04 ! protein sumoylation GO:0016925 17 10 2,000 5,125E-06 7,826E-04 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 3,000 6,429E-06 9,239E-04 ! nucleus localization GO:0051647 22 11 2,000 7,029E-06 9,54E-04 ! cell junction organization GO:0034330 96 37 3,000 9,08E-06 1,168E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 9,348E-06 1,142E-03 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 1,012E-05 1,177E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 2,189E-05 2,431E-03 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 2,000 2,355E-05 2,501E-03 ! response to insulin stimulus GO:0032868 98 47 3,000 2,386E-05 2,429E-03 ! filopodium assembly GO:0046847 42 17 2,000 2,852E-05 2,787E-03 ! cell-substrate junction assembly GO:0007044 56 18 2,000 3,414E-05 3,208E-03 ! microspike assembly GO:0030035 46 18 2,000 3,414E-05 3,089E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 5,141E-05 4,486E-03 ! nuclear export GO:0051168 110 59 3,000 5,891E-05 4,963E-03 ! positive regulation of DNA replication GO:0045740 44 23 2,000 7,313E-05 5,956E-03 ! cellular response to reactive oxygen species GO:0034614 35 23 2,000 7,313E-05 5,763E-03 ! response to peptide hormone stimulus GO:0043434 129 64 3,000 8,113E-05 6,194E-03 ! regulation of lipid metabolic process GO:0019216 132 66 3,000 9,153E-05 6,776E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 9,449E-05 6,789E-03 ! keratinization GO:0031424 37 25 2,000 9,449E-05 6,595E-03 ! myeloid cell differentiation GO:0030099 126 67 3,000 9,707E-05 6,587E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 1,195E-04 7,893E-03 ! cellular response to oxidative stress GO:0034599 43 27 2,000 1,195E-04 7,685E-03 ! hypothalamus development GO:0021854 9 5 1,000 1,238E-04 7,755E-03 ! protein maturation by protein folding GO:0022417 14 5 1,000 1,238E-04 7,561E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,238E-04 7,377E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,238E-04 7,201E-03 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 1,000 1,238E-04 7,034E-03 ! sequestering of calcium ion GO:0051208 7 5 1,000 1,238E-04 6,874E-03 ! spliceosomal snRNP biogenesis GO:0000387 40 28 2,000 1,335E-04 7,25E-03 ! cell-matrix adhesion GO:0007160 181 76 3,000 1,585E-04 8,42E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 1,646E-04 8,558E-03 ! male gonad development GO:0008584 56 31 2,000 1,818E-04 9,254E-03 ! interaction with symbiont GO:0051702 14 6 1,000 1,853E-04 9,237E-03 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 1,000 1,853E-04 9,052E-03 ! cell-substrate adhesion GO:0031589 189 82 3,000 2,126E-04 0,01018482 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 2,441E-04 0,01146933 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,588E-04 0,01192816 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 2,588E-04 0,01170726 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 1,000 2,588E-04 0,01149441 GO:0031958|corticosteroid receptor signaling pathway, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 2,588E-04 0,01128915 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 2,588E-04 0,01109109 ! regulation of meiosis GO:0040020 12 7 1,000 2,588E-04 0,01089987 GO:0051445|regulation of meiotic cell cycle, ! protein localization in nucleus GO:0034504 192 89 3,000 2,912E-04 0,0120573 ! positive regulation of DNA metabolic process GO:0051054 77 38 2,000 3,351E-04 0,01364414 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 3,442E-04 0,01378631 ! ER overload response GO:0006983 13 8 1,000 3,442E-04 0,01356395 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 3,442E-04 0,01334865 ! regulation of respiratory burst GO:0060263 12 8 1,000 3,442E-04 0,01314008 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 1,000 3,442E-04 0,01293793 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 4,043E-04 0,01496539 ! RNA export from nucleus GO:0006405 61 41 2,000 4,202E-04 0,0153206 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 4,202E-04 0,01509529 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,416E-04 0,01563377 ! regulation of glycolysis GO:0006110 20 9 1,000 4,416E-04 0,01541043 ! middle ear morphogenesis GO:0042474 14 9 1,000 4,416E-04 0,01519338 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 4,416E-04 0,01498236 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 4,416E-04 0,01477713 ! regulation of telomere maintenance GO:0032204 17 9 1,000 4,416E-04 0,01457743 ! positive regulation of transcription factor activity GO:0051091 71 43 2,000 4,839E-04 0,01576298 GO:0090047|positive regulation of transcription regulator activity, ! development of primary male sexual characteristics GO:0046546 80 43 2,000 4,839E-04 0,01555557 ! response to reactive oxygen species GO:0000302 75 44 2,000 5,18E-04 0,01643448 ! regulation of developmental growth GO:0048638 16 10 1,000 5,507E-04 0,01724721 ! protein heterooligomerization GO:0051291 17 10 1,000 5,507E-04 0,01702889 ! positive regulation of phagocytosis GO:0050766 14 10 1,000 5,507E-04 0,01681603 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 5,507E-04 0,01660842 GO:0043470|regulation of carbohydrate catabolic process, ! keratinocyte differentiation GO:0030216 81 45 2,000 5,536E-04 0,01649204 ! pigmentation GO:0043473 103 46 2,000 5,907E-04 0,01738513 ! positive regulation of DNA binding GO:0043388 83 48 2,000 6,695E-04 0,0194719 ! male sex differentiation GO:0046661 93 48 2,000 6,695E-04 0,01924282 ! cortical actin cytoskeleton organization GO:0030866 29 11 1,000 6,715E-04 0,01907463 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 6,715E-04 0,01885538 ! detection of mechanical stimulus GO:0050982 22 11 1,000 6,715E-04 0,01864111 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 6,715E-04 0,01843166 ! DNA methylation GO:0006306 19 11 1,000 6,715E-04 0,01822687 GO:0006305|DNA alkylation, ! apical protein localization GO:0045176 18 11 1,000 6,715E-04 0,01802657 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 6,715E-04 0,01783063 ! sequestering of metal ion GO:0051238 15 11 1,000 6,715E-04 0,0176389 ! regulation of embryonic development GO:0045995 35 11 1,000 6,715E-04 0,01745126 ! endocrine system development GO:0035270 109 50 2,000 7,548E-04 0,01941033 ! activation of caspase activity GO:0006919 95 50 2,000 7,548E-04 0,01920814 ! epidermal cell differentiation GO:0009913 87 50 2,000 7,548E-04 0,01901011 ! regulation of cell projection organization GO:0031344 135 51 2,000 7,999E-04 0,01994063 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 8,039E-04 0,01983772 ! cortical cytoskeleton organization GO:0030865 30 12 1,000 8,039E-04 0,01963934 ! virus-host interaction GO:0019048 30 12 1,000 8,039E-04 0,01944489 ! focal adhesion formation GO:0048041 37 12 1,000 8,039E-04 0,01925426 ! entry into host cell GO:0030260 34 12 1,000 8,039E-04 0,01906732 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! regulation of phagocytosis GO:0050764 17 12 1,000 8,039E-04 0,01888398 ! histone acetylation GO:0016573 27 12 1,000 8,039E-04 0,01870414 ! peptidyl-lysine modification GO:0018205 21 12 1,000 8,039E-04 0,01852768 ! positive regulation of binding GO:0051099 88 52 2,000 8,467E-04 0,01933161 ! regulation of translational initiation GO:0006446 87 54 2,000 9,454E-04 0,02138539 ! regulation of cell shape GO:0008360 142 54 2,000 9,454E-04 0,0211892 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 9,479E-04 0,02105118 ! asymmetric protein localization GO:0008105 24 13 1,000 9,479E-04 0,02086153 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 9,479E-04 0,02067526 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of steroid biosynthetic process GO:0050810 20 13 1,000 9,479E-04 0,0204923 ! regulation of DNA replication GO:0006275 105 56 2,000 1,051E-03 0,02252517 ! cell-cell junction assembly GO:0007043 32 14 1,000 1,103E-03 0,02343742 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,103E-03 0,02323537 ! positive regulation of caspase activity GO:0043280 108 57 2,000 1,107E-03 0,02310727 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 112 58 2,000 1,164E-03 0,02409898 ! maintenance of location GO:0051235 124 58 2,000 1,164E-03 0,02389646 ! establishment of organelle localization GO:0051656 122 59 2,000 1,223E-03 0,02490257 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,27E-03 0,0256426 ! cell killing GO:0001906 32 15 1,000 1,27E-03 0,02543242 ! actin filament polymerization GO:0030041 27 15 1,000 1,27E-03 0,02522565 ! viral reproductive process GO:0022415 132 62 2,000 1,412E-03 0,02782053 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,448E-03 0,0283023 ! pituitary gland development GO:0021983 30 16 1,000 1,448E-03 0,02807768 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,479E-03 0,02844816 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 1,548E-03 0,02953791 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 1,548E-03 0,02930894 ! regulation of survival gene product expression GO:0045884 38 17 1,000 1,637E-03 0,03077078 ! complement activation, alternative pathway GO:0006957 19 17 1,000 1,637E-03 0,03053589 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 1,637E-03 0,03030456 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 1,637E-03 0,03007671 ! regulation of cytokine biosynthetic process GO:0042035 108 66 2,000 1,691E-03 0,03083004 ! gonad development GO:0008406 115 66 2,000 1,691E-03 0,03060167 ! limbic system development GO:0021761 40 18 1,000 1,838E-03 0,03301326 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 1,838E-03 0,03277228 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,838E-03 0,0325348 ! viral reproduction GO:0016032 142 68 2,000 1,843E-03 0,03238316 ! cell projection assembly GO:0030031 138 68 2,000 1,843E-03 0,03215185 ! negative regulation of kinase activity GO:0033673 145 70 2,000 2,002E-03 0,03469036 ! activation of immune response GO:0002253 120 70 2,000 2,002E-03 0,03444606 ! regulation of lipid biosynthetic process GO:0046890 28 19 1,000 2,049E-03 0,03500975 ! memory GO:0007613 34 19 1,000 2,049E-03 0,03476663 ! cellular response to hydrogen peroxide GO:0070301 25 19 1,000 2,049E-03 0,03452686 GO:0042744|hydrogen peroxide catabolic process, ! response to lipopolysaccharide GO:0032496 34 19 1,000 2,049E-03 0,03429037 ! peptide cross-linking GO:0018149 39 19 1,000 2,049E-03 0,0340571 ! protein export from nucleus GO:0006611 40 19 1,000 2,049E-03 0,03382699 ! regulation of steroid metabolic process GO:0019218 35 19 1,000 2,049E-03 0,03359996 ! cellular pigmentation GO:0033059 37 19 1,000 2,049E-03 0,03337596 ! actin filament organization GO:0007015 167 72 2,000 2,17E-03 0,03511155 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,272E-03 0,03651172 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,272E-03 0,03627308 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,272E-03 0,03603755 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 2,272E-03 0,03580505 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,272E-03 0,03557553 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 2,272E-03 0,03534893 ! actin filament bundle formation GO:0051017 47 20 1,000 2,272E-03 0,0351252 ! cell-cell junction organization GO:0045216 43 20 1,000 2,272E-03 0,03490429 ! acute inflammatory response GO:0002526 118 74 2,000 2,347E-03 0,03583209 ! regulation of caspase activity GO:0043281 136 74 2,000 2,347E-03 0,03560953 ! negative regulation of transferase activity GO:0051348 155 74 2,000 2,347E-03 0,03538972 ! organelle localization GO:0051640 155 74 2,000 2,347E-03 0,0351726 ! regulation of transcription factor activity GO:0051090 137 75 2,000 2,438E-03 0,03632125 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 2,000 2,438E-03 0,03610112 ! lipid phosphorylation GO:0046834 43 21 1,000 2,505E-03 0,0368661 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 2,505E-03 0,03664534 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 2,505E-03 0,03642722 ! diencephalon development GO:0021536 36 21 1,000 2,505E-03 0,03621167 ! learning or memory GO:0007611 161 76 2,000 2,532E-03 0,03638567 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 2,628E-03 0,03754276 ! microtubule-based transport GO:0010970 59 22 1,000 2,749E-03 0,03904752 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 2,749E-03 0,03882181 ! apoptotic nuclear changes GO:0030262 34 22 1,000 2,749E-03 0,0385987 ! cell aging GO:0007569 48 22 1,000 2,749E-03 0,03837813 ! cytolysis GO:0019835 27 22 1,000 2,749E-03 0,03816008 ! peptidyl-serine modification GO:0018209 50 22 1,000 2,749E-03 0,03794448 ! protein stabilization GO:0050821 41 22 1,000 2,749E-03 0,03773131 ! blood coagulation GO:0007596 151 79 2,000 2,826E-03 0,03857313 GO:0050817|coagulation, ! development of primary sexual characteristics GO:0045137 143 80 2,000 2,929E-03 0,03975112 ! gluconeogenesis GO:0006094 38 23 1,000 3,004E-03 0,04054582 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 3,004E-03 0,04032304 ! DNA modification GO:0006304 36 23 1,000 3,004E-03 0,04010269 ! response to molecule of bacterial origin GO:0002237 40 23 1,000 3,004E-03 0,03988474 ! regulation of peptidase activity GO:0052547 150 82 2,000 3,141E-03 0,04147602 ! protein import into nucleus GO:0006606 174 82 2,000 3,141E-03 0,04125303 ! nuclear import GO:0051170 177 83 2,000 3,25E-03 0,04246201 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 3,27E-03 0,04248639 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 3,27E-03 0,04226159 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 3,27E-03 0,04203917 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 3,27E-03 0,04181907 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! hemostasis GO:0007599 165 85 2,000 3,476E-03 0,04422941 ! protein tetramerization GO:0051262 57 25 1,000 3,546E-03 0,04488046 ! mitochondrion organization GO:0007005 159 87 2,000 3,711E-03 0,04673504 ! initiation of viral infection GO:0019059 60 26 1,000 3,832E-03 0,0480106 ! pyruvate metabolic process GO:0006090 43 26 1,000 3,832E-03 0,04776565 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 3,832E-03 0,04752319 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 3,832E-03 0,04728317 ! hydrogen peroxide metabolic process GO:0042743 35 26 1,000 3,832E-03 0,04704557 ! regulation of DNA binding GO:0051101 167 89 2,000 3,956E-03 0,04832167 ! regulation of chromosome organization GO:0033044 49 27 1,000 4,129E-03 0,05018741 ! gland development GO:0048732 220 91 2,000 4,21E-03 0,05091851 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 4,437E-03 0,05339186 ! protein amino acid acylation GO:0043543 59 28 1,000 4,437E-03 0,05313014 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 4,437E-03 0,05287097 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 4,474E-03 0,05306057 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 4,754E-03 0,05610879 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 4,754E-03 0,05583903 ! somitogenesis GO:0001756 52 29 1,000 4,754E-03 0,05557186 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 4,754E-03 0,05530723 ! sex differentiation GO:0007548 171 96 2,000 4,889E-03 0,05660167 ! acute-phase response GO:0006953 50 30 1,000 5,082E-03 0,05856319 ! complement activation, classical pathway GO:0006958 51 30 1,000 5,082E-03 0,05828825 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 1,000 5,082E-03 0,05801587 ! immune response-activating signal transduction GO:0002757 58 30 1,000 5,082E-03 0,05774603 GO:0002764|immune response-regulating signal transduction, ! leukocyte differentiation GO:0002521 232 98 2,000 5,177E-03 0,05855715 ! ovulation cycle process GO:0022602 55 31 1,000 5,42E-03 0,06101843 ! iron ion homeostasis GO:0055072 60 31 1,000 5,42E-03 0,06073852 ! mRNA transport GO:0051028 185 100 2,000 5,476E-03 0,06108832 ! positive regulation of immune response GO:0050778 175 100 2,000 5,476E-03 0,06081065 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 1,000 5,768E-03 0,06376082 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 5,768E-03 0,06347361 ! response to mechanical stimulus GO:0009612 60 32 1,000 5,768E-03 0,06318897 ! hexose biosynthetic process GO:0019319 53 32 1,000 5,768E-03 0,06290688 ! ovulation cycle GO:0042698 57 32 1,000 5,768E-03 0,06262729 ! positive regulation of catabolic process GO:0009896 72 32 1,000 5,768E-03 0,06235018 ! response to hydrogen peroxide GO:0042542 56 34 1,000 6,494E-03 0,06988689 ! positive regulation of endocytosis GO:0045807 56 35 1,000 6,871E-03 0,07362722 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 1,000 7,259E-03 0,0774389 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 7,259E-03 0,07710221 ! maintenance of protein location in cell GO:0032507 89 37 1,000 7,656E-03 0,0809682 ! female gonad development GO:0008585 71 37 1,000 7,656E-03 0,08061919 ! regulation of protein stability GO:0031647 77 38 1,000 8,063E-03 0,08453762 ! glycogen metabolic process GO:0005977 63 38 1,000 8,063E-03 0,08417634 ! carbohydrate homeostasis GO:0033500 59 39 1,000 8,479E-03 0,08814539 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 64 39 1,000 8,479E-03 0,08777189 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 8,905E-03 0,09178981 GO:0006956|complement activation, ! learning GO:0007612 82 40 1,000 8,905E-03 0,09140413 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 8,905E-03 0,09102169 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 8,905E-03 0,09064243 ! feeding behavior GO:0007631 69 41 1,000 9,34E-03 0,09467694 ! maintenance of protein location GO:0045185 95 41 1,000 9,34E-03 0,09428572 ! ear morphogenesis GO:0042471 64 42 1,000 9,784E-03 0,09836572 ! alcohol biosynthetic process GO:0046165 65 42 1,000 9,784E-03 0,09796259 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 9,784E-03 0,09756274 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,0102379 0,10167152 ! glucose transport GO:0015758 66 43 1,000 0,0102379 0,1012599 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,0102379 0,10085159 ! segmentation GO:0035282 78 43 1,000 0,0102379 0,10044657 ! neuron migration GO:0001764 85 43 1,000 0,0102379 0,10004478 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01070076 0,10415117 ! hexose transport GO:0008645 68 44 1,000 0,01070076 0,10373788 GO:0015749|monosaccharide transport, ! receptor-mediated endocytosis GO:0006898 98 45 1,000 0,01117272 0,10788517 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,01117272 0,10746043 ! biopolymer methylation GO:0043414 91 45 1,000 0,01117272 0,10703902 ! maintenance of location in cell GO:0051651 101 45 1,000 0,01117272 0,1066209 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,01165372 0,11077836 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01165372 0,11034899 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,01264257 0,11925021 ! cellular component disassembly GO:0022411 89 48 1,000 0,01264257 0,11879155 ! methylation GO:0032259 97 48 1,000 0,01264257 0,11833641 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,01315028 0,12261887 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,01366676 0,12695019 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01366676 0,12646932 ! viral infectious cycle GO:0019058 104 51 1,000 0,01419194 0,13083362 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,01419194 0,13034176 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,01419194 0,12985359 ! excretion GO:0007588 87 52 1,000 0,01472575 0,1342351 ! histone modification GO:0016570 104 52 1,000 0,01472575 0,13373608 ! positive regulation of growth GO:0045927 96 53 1,000 0,01526812 0,13814825 ! covalent chromatin modification GO:0016569 115 54 1,000 0,015819 0,14260447 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,0163783 0,14710367 ! heart morphogenesis GO:0003007 105 57 1,000 0,01752195 0,15679903 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01760028 0,15692508 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01760028 0,15635444 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,01760028 0,15578794 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01760028 0,15522553 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01760028 0,15466717 ! neuron fate determination GO:0048664 7 5 0,000 0,01760028 0,1541128 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01760028 0,1535624 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01760028 0,15301592 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01760028 0,15247331 ! polyol transport GO:0015791 12 5 0,000 0,01760028 0,15193453 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01760028 0,15139955 ! response to superoxide GO:0000303 10 5 0,000 0,01760028 0,15086832 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01760028 0,15034081 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01760028 0,14981698 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01760028 0,14929678 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01760028 0,14878018 ! female meiosis GO:0007143 10 5 0,000 0,01760028 0,14826715 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01760028 0,14775764 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01760028 0,14725162 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01760028 0,14674905 ! cobalt ion transport GO:0006824 11 5 0,000 0,01760028 0,14624991 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01760028 0,14575414 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01760028 0,14526173 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01760028 0,14477263 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01760028 0,14428682 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01760028 0,14380426 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01760028 0,14332491 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01760028 0,14284875 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01760028 0,14237574 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01760028 0,14190585 ! transposition GO:0032196 9 5 0,000 0,01760028 0,14143905 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,01760028 0,14097532 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,01760028 0,14051462 ! negative chemotaxis GO:0050919 16 5 0,000 0,01760028 0,14005691 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01760028 0,13960218 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01760028 0,1391504 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01760028 0,13870152 ! behavioral response to pain GO:0048266 10 5 0,000 0,01760028 0,13825554 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01760028 0,13781241 ! Notch receptor processing GO:0007220 11 5 0,000 0,01760028 0,13737212 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01760028 0,13693463 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01760028 0,13649991 ! micturition GO:0060073 9 5 0,000 0,01760028 0,13606795 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01760028 0,13563871 ! copulation GO:0007620 9 5 0,000 0,01760028 0,13521218 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01760028 0,13478831 ! bioluminescence GO:0008218 9 5 0,000 0,01760028 0,1343671 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01760028 0,13394851 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01760028 0,13353252 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01760028 0,13311911 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01760028 0,13270825 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01760028 0,13229991 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01760028 0,13189409 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01760028 0,13149074 ! grooming behavior GO:0007625 6 5 0,000 0,01760028 0,13108985 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01760028 0,13069141 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01760028 0,13029537 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,01760028 0,12990173 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01760028 0,12951046 ! response to protozoan GO:0001562 13 5 0,000 0,01760028 0,12912154 ! lymph vessel development GO:0001945 10 5 0,000 0,01760028 0,12873495 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01760028 0,12835066 ! endochondral ossification GO:0001958 17 5 0,000 0,01760028 0,12796867 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01760028 0,12758894 ! single strand break repair GO:0000012 8 5 0,000 0,01760028 0,12721146 ! parathyroid gland development GO:0060017 14 5 0,000 0,01760028 0,1268362 ! anagen GO:0042640 7 5 0,000 0,01760028 0,12646315 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01760028 0,12609229 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01760028 0,1257236 ! cytokine secretion GO:0050663 15 5 0,000 0,01760028 0,12535706 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01760028 0,12499265 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01760028 0,12463035 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01760028 0,12427015 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01760028 0,12391202 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01760028 0,12355595 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01760028 0,12320193 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01760028 0,12284992 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01760028 0,12249992 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01760028 0,12215191 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01760028 0,12180587 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01760028 0,12146179 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01760028 0,12111964 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01760028 0,12077942 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01760028 0,1204411 ! microvillus organization GO:0032528 8 5 0,000 0,01760028 0,12010467 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,01760028 0,11977012 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01760028 0,11943742 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01760028 0,11910657 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01760028 0,11877755 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01760028 0,11845034 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01760028 0,11812492 ! polyol catabolic process GO:0046174 9 5 0,000 0,01760028 0,11780129 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01760028 0,11747943 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01760028 0,11715932 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01760028 0,11684096 ! muscle cell migration GO:0014812 8 5 0,000 0,01760028 0,11652432 ! mitochondrial fission GO:0000266 8 5 0,000 0,01760028 0,11620938 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01760028 0,11589615 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01760028 0,1155846 ! mRNA transcription GO:0009299 10 5 0,000 0,01760028 0,11527472 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01760028 0,1149665 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01760028 0,11465993 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01760028 0,11435498 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01760028 0,11405165 ! monocyte activation GO:0042117 10 5 0,000 0,01760028 0,11374993 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01760028 0,11344979 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01760028 0,11315124 ! response to food GO:0032094 6 5 0,000 0,01760028 0,11285426 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01760028 0,11255883 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01760028 0,11226494 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01760028 0,11197258 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01760028 0,11168175 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01760028 0,11139242 ! forebrain neuron development GO:0021884 13 5 0,000 0,01760028 0,11110458 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01760028 0,11081823 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01760028 0,11053335 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01760028 0,11024993 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01760028 0,10996796 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01760028 0,10968743 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01760028 0,10940833 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01760028 0,10913064 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01760028 0,10885436 ! lipid glycosylation GO:0030259 7 5 0,000 0,01760028 0,10857948 ! nucleobase transport GO:0015851 6 5 0,000 0,01760028 0,10830598 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01760028 0,10803385 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01760028 0,10776309 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01760028 0,10749368 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01760028 0,10722562 ! basic amino acid transport GO:0015802 12 5 0,000 0,01760028 0,10695889 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01760028 0,10669348 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01760028 0,10642939 ! actin nucleation GO:0045010 11 5 0,000 0,01760028 0,1061666 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01760028 0,1059051 ! depurination GO:0045007 5 5 0,000 0,01760028 0,10564489 ! depyrimidination GO:0045008 10 5 0,000 0,01760028 0,10538596 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01760028 0,10512829 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01760028 0,10487188 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01760028 0,10461672 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01760028 0,1043628 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01760028 0,1041101 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01760028 0,10385863 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01760028 0,10360837 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01760028 0,10335931 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01760028 0,10311144 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01760028 0,10286477 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01760028 0,10261927 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01760028 0,10237493 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01760028 0,10213176 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01760028 0,10188974 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01760028 0,10164887 ! response to arsenic GO:0046685 11 5 0,000 0,01760028 0,10140913 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01760028 0,10117052 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01760028 0,10093303 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01760028 0,10069666 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01760028 0,10046138 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01760028 0,10022721 ! response to mercury ion GO:0046689 8 5 0,000 0,01760028 0,09999412 ! response to cadmium ion GO:0046686 7 5 0,000 0,01760028 0,09976212 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01760028 0,09953119 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01760028 0,09930132 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01760028 0,09907252 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01760028 0,09884476 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01760028 0,09861806 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01760028 0,09839239 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01760028 0,09816774 ! decidualization GO:0046697 11 5 0,000 0,01760028 0,09794413 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01760028 0,09772153 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01760028 0,09749994 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01760028 0,09727935 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01760028 0,09705976 ! embryonic cleavage GO:0040016 6 5 0,000 0,01760028 0,09684115 ! peroxisome fission GO:0016559 5 5 0,000 0,01760028 0,09662353 ! histone demethylation GO:0016577 13 5 0,000 0,01760028 0,09640689 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01760028 0,09619121 ! mitotic recombination GO:0006312 9 5 0,000 0,01760028 0,0959765 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01760028 0,09576274 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01760028 0,09554994 ! metaphase plate congression GO:0051310 7 5 0,000 0,01760028 0,09533808 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01760028 0,09512715 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01760028 0,09491716 ! enteric nervous system development GO:0048484 8 5 0,000 0,01760028 0,09470809 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01760028 0,09449994 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01760028 0,0942927 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01760028 0,09408637 ! muscle cell proliferation GO:0033002 12 5 0,000 0,01760028 0,09388094 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01760028 0,09367641 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01760028 0,09347277 ! B cell homeostasis GO:0001782 13 5 0,000 0,01760028 0,09327 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01760028 0,09306812 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01760028 0,09286711 ! metaphase GO:0051323 11 5 0,000 0,01760028 0,09266697 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01760028 0,09246768 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01760028 0,09226925 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01760028 0,09207168 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01760028 0,09187494 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01760028 0,09167905 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01760028 0,09148398 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01760028 0,09128975 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01760028 0,09109634 ! response to redox state GO:0051775 6 5 0,000 0,01760028 0,09090375 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01760028 0,09071197 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01760028 0,09052099 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01760028 0,09033082 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01760028 0,09014145 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01760028 0,08995287 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01760028 0,08976508 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01760028 0,08957807 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01760028 0,08939183 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01760028 0,08920637 ! striatum development GO:0021756 14 5 0,000 0,01760028 0,08902168 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01760028 0,08883775 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01760028 0,08865458 ! glial cell migration GO:0008347 10 5 0,000 0,01760028 0,08847217 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01760028 0,0882905 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01760028 0,08810957 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,01760028 0,08792939 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01760028 0,08774994 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01760028 0,08757123 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01760028 0,08739324 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01760028 0,08721597 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01760028 0,08703942 ! neuroprotection GO:0043526 8 5 0,000 0,01760028 0,08686358 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01760028 0,08668845 ! regulation of sensory perception GO:0051931 8 5 0,000 0,01760028 0,08651403 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01760028 0,08634031 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01760028 0,08616728 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01760028 0,08599494 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01760028 0,0858233 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01760028 0,08565234 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01760028 0,08548205 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01760028 0,08531244 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01760028 0,08514351 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01760028 0,08497524 ! spindle assembly GO:0051225 6 5 0,000 0,01760028 0,08480764 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01760028 0,08464069 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01760028 0,08447441 ! protein palmitoylation GO:0018345 12 5 0,000 0,01760028 0,08430877 ! drug metabolic process GO:0017144 7 5 0,000 0,01760028 0,08414378 ! stem cell division GO:0017145 11 5 0,000 0,01760028 0,08397944 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01760028 0,08381574 ! organ regeneration GO:0031100 7 5 0,000 0,01760028 0,08365267 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01760028 0,08349024 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01760028 0,08332843 ! regulation of actin filament length GO:0030832 118 58 1,000 0,01810617 0,08555777 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,01810617 0,0853926 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01810617 0,08522806 ! lipid modification GO:0030258 112 60 1,000 0,01929904 0,09066839 ! DNA catabolic process GO:0006308 94 60 1,000 0,01929904 0,09049436 ! regulation of endocytosis GO:0030100 104 60 1,000 0,01929904 0,090321 ! regulation of cellular component size GO:0032535 125 61 1,000 0,01990758 0,09299085 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,0205241 0,09568772 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02108328 0,09810751 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02108328 0,09792099 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02108328 0,09773519 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02108328 0,09755008 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02108328 0,09736568 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02108328 0,09718197 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02108328 0,09699895 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02108328 0,09681662 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02108328 0,09663498 ! response to oxygen radical GO:0000305 11 6 0,000 0,02108328 0,09645401 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02108328 0,09627373 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02108328 0,09609411 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02108328 0,09591516 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02108328 0,09573688 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02108328 0,09555926 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02108328 0,0953823 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02108328 0,09520599 ! forebrain regionalization GO:0021871 9 6 0,000 0,02108328 0,09503034 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02108328 0,09485533 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02108328 0,09468096 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02108328 0,09450724 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02108328 0,09433415 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02108328 0,09416169 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02108328 0,09398986 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02108328 0,09381866 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02108328 0,09364808 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02108328 0,09347812 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02108328 0,09330877 ! malate metabolic process GO:0006108 13 6 0,000 0,02108328 0,09314004 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02108328 0,09297192 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02108328 0,0928044 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02108328 0,09263749 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02108328 0,09247117 ! protein refolding GO:0042026 15 6 0,000 0,02108328 0,09230545 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02108328 0,09214033 ! opsonization GO:0008228 8 6 0,000 0,02108328 0,09197579 ! mating behavior GO:0007617 7 6 0,000 0,02108328 0,09181184 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02108328 0,09164848 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02108328 0,09148569 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02108328 0,09132348 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02108328 0,09116185 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02108328 0,09100078 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02108328 0,09084029 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02108328 0,09068036 ! toxin metabolic process GO:0009404 11 6 0,000 0,02108328 0,09052099 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02108328 0,09036218 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02108328 0,09020393 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02108328 0,09004623 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02108328 0,08988908 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02108328 0,08973248 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02108328 0,08957642 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02108328 0,08942091 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02108328 0,08926593 ! thymic T cell selection GO:0045061 16 6 0,000 0,02108328 0,08911149 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02108328 0,08895759 ! protein lipoylation GO:0009249 10 6 0,000 0,02108328 0,08880421 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02108328 0,08865137 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02108328 0,08849904 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02108328 0,08834724 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02108328 0,08819596 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02108328 0,0880452 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02108328 0,08789495 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02108328 0,08774522 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02108328 0,08759599 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02108328 0,08744727 ! hyperosmotic response GO:0006972 10 6 0,000 0,02108328 0,08729906 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02108328 0,08715134 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02108328 0,08700413 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02108328 0,08685741 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02108328 0,08671118 ! urea metabolic process GO:0019627 7 6 0,000 0,02108328 0,08656545 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02108328 0,08642021 ! neutrophil activation GO:0042119 7 6 0,000 0,02108328 0,08627545 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02108328 0,08613118 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02108328 0,08598738 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02108328 0,08584407 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02108328 0,08570124 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02108328 0,08555888 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02108328 0,08541699 ! neuron apoptosis GO:0051402 15 6 0,000 0,02108328 0,08527557 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02108328 0,08513462 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02108328 0,08499413 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02108328 0,08485411 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02108328 0,08471454 ! carnitine transport GO:0015879 10 6 0,000 0,02108328 0,08457544 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02108328 0,08443679 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02108328 0,0842986 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02108328 0,08416085 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02108328 0,08402356 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02108328 0,08388672 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02108328 0,08375031 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02108328 0,08361436 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02108328 0,08347884 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02108328 0,08334376 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02108328 0,08320912 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02108328 0,08307491 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02108328 0,08294113 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02108328 0,08280779 ! response to UV-C GO:0010225 14 6 0,000 0,02108328 0,08267487 ! astrocyte development GO:0014002 16 6 0,000 0,02108328 0,08254238 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02108328 0,08241031 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02108328 0,08227866 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02108328 0,08214744 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02108328 0,08201663 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02108328 0,08188624 ! response to copper ion GO:0046688 10 6 0,000 0,02108328 0,08175626 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02108328 0,08162669 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02108328 0,08149754 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02108328 0,08136879 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02108328 0,08124045 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02108328 0,08111251 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02108328 0,08098497 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02108328 0,08085784 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02108328 0,0807311 ! hair follicle maturation GO:0048820 8 6 0,000 0,02108328 0,08060476 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02108328 0,08047882 ! Schwann cell development GO:0014044 15 6 0,000 0,02108328 0,08035327 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02108328 0,0802281 ! response to pheromone GO:0019236 6 6 0,000 0,02108328 0,08010333 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02108328 0,07997895 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02108328 0,07985495 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02108328 0,07973134 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02108328 0,0796081 ! subpallium development GO:0021544 15 6 0,000 0,02108328 0,07948525 ! neural tube patterning GO:0021532 8 6 0,000 0,02108328 0,07936278 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02108328 0,07924068 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02108328 0,07911896 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02108328 0,07899761 ! G2 phase GO:0051319 16 6 0,000 0,02108328 0,07887664 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02108328 0,07875603 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02108328 0,07863579 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02108328 0,07851592 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02108328 0,07839641 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02108328 0,07827727 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02108328 0,07815849 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02108328 0,07804007 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02108328 0,077922 ! receptor internalization GO:0031623 11 6 0,000 0,02108328 0,07780429 ! plasminogen activation GO:0031639 9 6 0,000 0,02108328 0,07768694 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02108328 0,07756994 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02108328 0,0774533 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02108328 0,077337 ! protein deubiquitination GO:0016579 16 6 0,000 0,02108328 0,07722105 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02108328 0,07710545 ! protein destabilization GO:0031648 9 6 0,000 0,02108328 0,0769902 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02108328 0,07687529 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02108328 0,07676072 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02108328 0,07664649 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02108328 0,07653261 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02108328 0,07641906 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02108328 0,07630584 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02108328 0,07619296 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02108328 0,07608042 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02108328 0,07596821 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02108328 0,07585632 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02108328 0,07574477 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02108328 0,07563354 ! neural plate development GO:0001840 9 6 0,000 0,02108328 0,07552264 ! catecholamine transport GO:0051937 9 6 0,000 0,02108328 0,07541207 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02108328 0,07530182 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02108328 0,07519189 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02108328 0,07508228 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02108328 0,07497299 ! maternal placenta development GO:0001893 12 6 0,000 0,02108328 0,07486402 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02108328 0,07475536 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02108328 0,07464702 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02108328 0,07453899 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02108328 0,07443128 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02108328 0,07432387 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02108328 0,07421678 GO:0055081|anion homeostasis, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,02114853 0,07433936 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,02242089 0,07869863 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,02242089 0,07858572 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,02242089 0,07847313 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 157 65 1,000 0,02242089 0,07836086 ! ear development GO:0043583 114 66 1,000 0,0230687 0,08050977 ! steroid hormone receptor signaling pathway GO:0030518 146 66 1,000 0,0230687 0,08039492 ! activation of MAPK activity GO:0000187 124 67 1,000 0,02372418 0,08256149 ! detection of external stimulus GO:0009581 102 68 1,000 0,02438726 0,08474832 ! adaptive immune response GO:0002250 126 68 1,000 0,02438726 0,08462794 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! tRNA transcription GO:0009304 17 7 0,000 0,02455403 0,08508579 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02455403 0,08496528 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02455403 0,0848451 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02455403 0,08472526 ! regulation of helicase activity GO:0051095 16 7 0,000 0,02455403 0,08460576 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02455403 0,0844866 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02455403 0,08436777 ! sleep GO:0030431 16 7 0,000 0,02455403 0,08424928 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02455403 0,08413112 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02455403 0,08401328 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02455403 0,08389578 ! prostate gland development GO:0030850 14 7 0,000 0,02455403 0,08377861 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02455403 0,08366176 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02455403 0,08354524 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02455403 0,08342905 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02455403 0,08331317 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02455403 0,08319762 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02455403 0,08308239 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02455403 0,08296748 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02455403 0,08285288 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02455403 0,0827386 ! glycolipid transport GO:0046836 11 7 0,000 0,02455403 0,08262464 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02455403 0,08251098 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02455403 0,08239764 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02455403 0,08228462 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02455403 0,0821719 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02455403 0,08205949 ! mRNA stabilization GO:0048255 18 7 0,000 0,02455403 0,08194738 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02455403 0,08183559 ! fibril organization GO:0043206 17 7 0,000 0,02455403 0,08172409 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02455403 0,0816129 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02455403 0,08150202 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02455403 0,08139143 ! lipoprotein transport GO:0042953 14 7 0,000 0,02455403 0,08128115 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02455403 0,08117116 ! rhythmic behavior GO:0007622 17 7 0,000 0,02455403 0,08106147 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02455403 0,08095207 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02455403 0,08084297 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02455403 0,08073417 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02455403 0,08062565 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02455403 0,08051743 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02455403 0,0804095 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02455403 0,08030185 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,02455403 0,0801945 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02455403 0,08008743 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02455403 0,07998065 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02455403 0,07987415 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02455403 0,07976793 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02455403 0,079662 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02455403 0,07955635 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02455403 0,07945097 ! spinal cord patterning GO:0021511 14 7 0,000 0,02455403 0,07934588 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02455403 0,07924106 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02455403 0,07913652 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02455403 0,07903226 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02455403 0,07892827 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02455403 0,07882455 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02455403 0,07872111 ! ovulation GO:0030728 10 7 0,000 0,02455403 0,07861794 ! adenohypophysis development GO:0021984 11 7 0,000 0,02455403 0,07851503 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02455403 0,0784124 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02455403 0,07831003 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02455403 0,07820793 ! microtubule nucleation GO:0007020 21 7 0,000 0,02455403 0,0781061 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02455403 0,07800453 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02455403 0,07790323 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02455403 0,07780219 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02455403 0,07770141 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02455403 0,07760089 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02455403 0,07750063 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02455403 0,07740063 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02455403 0,07730088 ! galactose metabolic process GO:0006012 13 7 0,000 0,02455403 0,0772014 ! vesicle fusion GO:0006906 20 7 0,000 0,02455403 0,07710217 ! response to dietary excess GO:0002021 8 7 0,000 0,02455403 0,07700319 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02455403 0,07690447 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02455403 0,076806 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02455403 0,07670778 ! organ growth GO:0035265 15 7 0,000 0,02455403 0,07660981 ! nucleoside transport GO:0015858 11 7 0,000 0,02455403 0,0765121 ! nucleoside salvage GO:0043174 11 7 0,000 0,02455403 0,07641463 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02455403 0,07631741 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02455403 0,07622044 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02455403 0,07612371 ! parturition GO:0007567 16 7 0,000 0,02455403 0,07602723 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02455403 0,07593099 ! rRNA modification GO:0000154 14 7 0,000 0,02455403 0,075835 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02455403 0,07573925 ! spindle checkpoint GO:0031577 16 7 0,000 0,02455403 0,07564374 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02455403 0,07554847 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02455403 0,07545344 ! monocyte differentiation GO:0030224 16 7 0,000 0,02455403 0,07535865 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02455403 0,0752641 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02455403 0,07516978 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02455403 0,0750757 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02455403 0,07498186 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,02455403 0,07488825 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02455403 0,07479487 ! fibrinolysis GO:0042730 11 7 0,000 0,02455403 0,07470172 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02455403 0,07460881 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02455403 0,07451613 ! eating behavior GO:0042755 8 7 0,000 0,02455403 0,07442368 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02455403 0,07433146 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02455403 0,07423946 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02455403 0,07414769 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02455403 0,07405615 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02455403 0,07396484 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02455403 0,07387375 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02455403 0,07378288 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02455403 0,07369224 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02455403 0,07360182 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02455403 0,07351162 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02455403 0,07342165 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02455403 0,07333189 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02455403 0,07324235 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02455403 0,07315303 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02455403 0,07306393 ! histone ubiquitination GO:0016574 9 7 0,000 0,02455403 0,07297504 ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02455403 0,07288637 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02455403 0,07279792 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02455403 0,07270968 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02455403 0,07262165 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02455403 0,07253384 ! transcription termination GO:0006353 14 7 0,000 0,02455403 0,07244624 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02455403 0,07235885 ! anaphase GO:0051322 18 7 0,000 0,02455403 0,07227167 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02455403 0,0721847 ! axonal fasciculation GO:0007413 19 7 0,000 0,02455403 0,07209794 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02455403 0,07201139 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02455403 0,07192504 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02455403 0,0718389 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02455403 0,07175297 ! diuresis GO:0030146 12 7 0,000 0,02455403 0,07166725 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02455403 0,07158172 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02455403 0,07149641 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02455403 0,07141129 ! antibiotic transport GO:0042891 9 7 0,000 0,02455403 0,07132638 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02455403 0,07124167 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02455403 0,07115716 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02455403 0,07107285 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02455403 0,07098874 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02455403 0,07090483 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02455403 0,07082112 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02455403 0,0707376 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02455403 0,07065428 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02455403 0,07057116 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02455403 0,07048823 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02455403 0,0704055 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02455403 0,07032296 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02455403 0,07024061 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02455403 0,07015846 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02455403 0,0700765 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02455403 0,06999473 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02455403 0,06991315 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02455403 0,06983176 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02455403 0,06975056 ! muscle adaptation GO:0043500 13 7 0,000 0,02455403 0,06966955 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02455403 0,06958873 ! retina homeostasis GO:0001895 12 7 0,000 0,02455403 0,06950809 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02455403 0,06942764 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02455403 0,06934738 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02455403 0,0692673 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02455403 0,06918741 ! negative regulation of protein kinase activity GO:0006469 144 69 1,000 0,02505788 0,07052581 ! lung development GO:0030324 165 69 1,000 0,02505788 0,07044466 ! cell redox homeostasis GO:0045454 114 70 1,000 0,02573599 0,07226785 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,02573599 0,07218488 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 1,000 0,02642152 0,07402268 ! carbohydrate transport GO:0008643 114 72 1,000 0,02711442 0,07587689 ! respiratory tube development GO:0030323 171 72 1,000 0,02711442 0,07579007 ! humoral immune response GO:0006959 115 73 1,000 0,02781461 0,0776584 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02801257 0,07812181 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02801257 0,07803273 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,02801257 0,07794385 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02801257 0,07785518 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02801257 0,07776671 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02801257 0,07767844 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02801257 0,07759037 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02801257 0,07750249 ! male meiosis GO:0007140 9 8 0,000 0,02801257 0,07741482 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02801257 0,07732735 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02801257 0,07724007 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02801257 0,07715299 ! meiotic prophase I GO:0007128 14 8 0,000 0,02801257 0,07706611 ! response to zinc ion GO:0010043 12 8 0,000 0,02801257 0,07697942 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02801257 0,07689292 ! oligopeptide transport GO:0006857 16 8 0,000 0,02801257 0,07680662 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02801257 0,07672052 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02801257 0,0766346 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02801257 0,07654888 ! signal peptide processing GO:0006465 12 8 0,000 0,02801257 0,07646335 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02801257 0,07637802 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02801257 0,07629287 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02801257 0,07620791 ! succinate metabolic process GO:0006105 17 8 0,000 0,02801257 0,07612314 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02801257 0,07603856 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02801257 0,07595416 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02801257 0,07586996 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02801257 0,07578594 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02801257 0,0757021 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02801257 0,07561846 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02801257 0,07553499 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02801257 0,07545171 ! reflex GO:0060004 17 8 0,000 0,02801257 0,07536861 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02801257 0,0752857 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02801257 0,07520297 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02801257 0,07512042 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02801257 0,07503805 ! pigment granule organization GO:0048753 17 8 0,000 0,02801257 0,07495586 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02801257 0,07487385 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02801257 0,07479202 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02801257 0,07471037 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02801257 0,0746289 ! histidine catabolic process GO:0006548 10 8 0,000 0,02801257 0,07454761 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02801257 0,07446649 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02801257 0,07438555 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02801257 0,07430478 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02801257 0,07422419 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02801257 0,07414377 ! melanin metabolic process GO:0006582 17 8 0,000 0,02801257 0,07406353 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02801257 0,07398346 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02801257 0,07390357 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02801257 0,07382384 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02801257 0,07374429 ! macrophage activation GO:0042116 13 8 0,000 0,02801257 0,07366491 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02801257 0,0735857 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02801257 0,07350666 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02801257 0,07342779 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02801257 0,07334909 ! purine salvage GO:0043101 12 8 0,000 0,02801257 0,07327056 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02801257 0,07319219 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02801257 0,073114 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02801257 0,07303597 ! osteoblast development GO:0002076 17 8 0,000 0,02801257 0,0729581 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02801257 0,07288041 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02801257 0,07280287 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02801257 0,07272551 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02801257 0,0726483 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02801257 0,07257126 ! response to UV-B GO:0010224 17 8 0,000 0,02801257 0,07249439 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02801257 0,07241767 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02801257 0,07234112 ! intermediate filament organization GO:0045109 12 8 0,000 0,02801257 0,07226473 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02801257 0,0721885 ! cellular extravasation GO:0045123 13 8 0,000 0,02801257 0,07211244 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02801257 0,07203653 ! response to antibiotic GO:0046677 11 8 0,000 0,02801257 0,07196078 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02801257 0,07188519 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02801257 0,07180976 ! DNA topological change GO:0006265 12 8 0,000 0,02801257 0,07173449 ! response to tropane GO:0014073 15 8 0,000 0,02801257 0,07165937 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02801257 0,07158442 ! melanosome transport GO:0032402 13 8 0,000 0,02801257 0,07150962 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02801257 0,07143497 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02801257 0,07136048 ! mast cell activation GO:0045576 14 8 0,000 0,02801257 0,07128615 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02801257 0,07121197 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02801257 0,07113794 ! gas homeostasis GO:0033483 14 8 0,000 0,02801257 0,07106407 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02801257 0,07099035 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02801257 0,07091679 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02801257 0,07084338 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02801257 0,07077012 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02801257 0,07069701 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02801257 0,07062405 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02801257 0,07055124 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02801257 0,07047858 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02801257 0,07040607 ! response to tumor cell GO:0002347 16 8 0,000 0,02801257 0,07033371 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02801257 0,0702615 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02801257 0,07018944 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02801257 0,07011752 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02801257 0,07004575 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02801257 0,06997413 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02801257 0,06990266 ! hormone catabolic process GO:0042447 17 8 0,000 0,02801257 0,06983133 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02801257 0,06976014 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02801257 0,06968911 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02801257 0,06961821 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02801257 0,06954746 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02801257 0,06947685 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02801257 0,06940639 ! adult feeding behavior GO:0008343 10 8 0,000 0,02801257 0,06933607 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02801257 0,06926589 ! ATP catabolic process GO:0006200 11 8 0,000 0,02801257 0,06919586 ! blastocyst growth GO:0001832 19 8 0,000 0,02801257 0,06912596 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02801257 0,06905621 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02801257 0,06898659 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02801257 0,06891712 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02801257 0,06884779 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02801257 0,0687786 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02801257 0,06870954 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02801257 0,06864062 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02801257 0,06857185 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02801257 0,06850321 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02801257 0,0684347 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02801257 0,06836634 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02801257 0,06829811 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02801257 0,06823001 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02801257 0,06816205 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02801257 0,06809423 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02801257 0,06802654 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02801257 0,06795899 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02801257 0,06789157 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02801257 0,06782428 ! respiratory system development GO:0060541 175 74 1,000 0,02852205 0,06898949 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,02923668 0,07064808 ! rhythmic process GO:0048511 142 75 1,000 0,02923668 0,07057827 ! regulation of actin cytoskeleton organization GO:0032956 167 76 1,000 0,02995843 0,0722492 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,03068724 0,07393386 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,03068724 0,07386102 ! regulation of catabolic process GO:0009894 173 77 1,000 0,03068724 0,07378832 ! antigen processing and presentation GO:0019882 117 78 1,000 0,03142307 0,07548334 ! axon extension GO:0048675 16 9 0,000 0,03145894 0,07549528 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,03145894 0,0754212 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,03145894 0,07534725 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03145894 0,07527346 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,03145894 0,0751998 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,03145894 0,07512629 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,03145894 0,07505293 ! reproductive behavior GO:0019098 22 9 0,000 0,03145894 0,07497971 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03145894 0,07490663 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,03145894 0,07483369 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,03145894 0,07476089 ! UTP metabolic process GO:0046051 10 9 0,000 0,03145894 0,07468824 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,03145894 0,07461573 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,03145894 0,07454335 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,03145894 0,07447112 ! artery development GO:0060840 25 9 0,000 0,03145894 0,07439903 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,03145894 0,07432708 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,03145894 0,07425526 ! equilibrioception GO:0050957 20 9 0,000 0,03145894 0,07418359 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,03145894 0,07411205 ! chemosensory behavior GO:0007635 21 9 0,000 0,03145894 0,07404065 ! microtubule bundle formation GO:0001578 22 9 0,000 0,03145894 0,07396939 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,03145894 0,07389827 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03145894 0,07382728 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,03145894 0,07375643 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,03145894 0,07368571 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,03145894 0,07361513 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,03145894 0,07354469 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03145894 0,07347438 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03145894 0,0734042 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,03145894 0,07333416 ! protein targeting to ER GO:0045047 25 9 0,000 0,03145894 0,07326425 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,03145894 0,07319447 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,03145894 0,07312483 ! T cell selection GO:0045058 27 9 0,000 0,03145894 0,07305532 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,03145894 0,07298594 ! glycine catabolic process GO:0006546 15 9 0,000 0,03145894 0,0729167 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,03145894 0,07284758 ! endosome organization GO:0007032 20 9 0,000 0,03145894 0,0727786 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03145894 0,07270974 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,03145894 0,07264102 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03145894 0,07257243 ! mannose metabolic process GO:0006013 13 9 0,000 0,03145894 0,07250396 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,03145894 0,07243563 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,03145894 0,07236742 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,03145894 0,07229934 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,03145894 0,07223139 ! receptor clustering GO:0043113 20 9 0,000 0,03145894 0,07216357 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,03145894 0,07209587 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03145894 0,0720283 ! retinol metabolic process GO:0042572 20 9 0,000 0,03145894 0,07196086 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,03145894 0,07189354 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,03145894 0,07182635 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,03145894 0,07175929 ! oligodendrocyte development GO:0014003 11 9 0,000 0,03145894 0,07169235 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,03145894 0,07162553 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03145894 0,07155884 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,03145894 0,07149228 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03145894 0,07142584 ! response to amine stimulus GO:0014075 13 9 0,000 0,03145894 0,07135952 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03145894 0,07129332 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,03145894 0,07122725 ! erythrocyte development GO:0048821 17 9 0,000 0,03145894 0,0711613 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03145894 0,07109547 ! renal water homeostasis GO:0003091 15 9 0,000 0,03145894 0,07102976 ! postreplication repair GO:0006301 25 9 0,000 0,03145894 0,07096417 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,03145894 0,07089871 ! icosanoid secretion GO:0032309 15 9 0,000 0,03145894 0,07083336 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03145894 0,07076814 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,03145894 0,07070303 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,03145894 0,07063805 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,03145894 0,07057319 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03145894 0,07050844 ! sterol catabolic process GO:0016127 14 9 0,000 0,03145894 0,07044381 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03145894 0,0703793 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,03145894 0,07031491 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,03145894 0,07025064 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,03145894 0,07018648 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,03145894 0,07012244 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,03145894 0,07005852 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,03145894 0,06999472 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,03145894 0,06993103 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,03145894 0,06986745 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,03145894 0,069804 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03145894 0,06974065 ! purine base metabolic process GO:0006144 25 9 0,000 0,03145894 0,06967742 ! pigment granule transport GO:0051904 17 9 0,000 0,03145894 0,06961431 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,03145894 0,06955131 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,03145894 0,06948843 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03145894 0,06942565 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,03145894 0,069363 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,03145894 0,06930045 ! mitochondrion localization GO:0051646 18 9 0,000 0,03145894 0,06923802 ! regulation of actin filament-based process GO:0032970 170 79 1,000 0,03216584 0,07073011 ! steroid biosynthetic process GO:0006694 146 79 1,000 0,03216584 0,0706665 ! protein oligomerization GO:0051259 149 79 1,000 0,03216584 0,07060301 ! response to hypoxia GO:0001666 178 81 1,000 0,03367201 0,07384266 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,0348932 0,07645209 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,0348932 0,07638358 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,0348932 0,0763152 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0348932 0,07624694 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,0348932 0,0761788 ! associative learning GO:0008306 21 10 0,000 0,0348932 0,07611078 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,0348932 0,07604289 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0348932 0,07597511 ! phosphate transport GO:0006817 24 10 0,000 0,0348932 0,07590746 ! cell volume homeostasis GO:0006884 17 10 0,000 0,0348932 0,07583993 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,0348932 0,07577251 ! CTP metabolic process GO:0046036 11 10 0,000 0,0348932 0,07570522 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,0348932 0,07563805 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0348932 0,07557099 ! GTP metabolic process GO:0046039 11 10 0,000 0,0348932 0,07550406 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,0348932 0,07543724 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,0348932 0,07537054 ! social behavior GO:0035176 29 10 0,000 0,0348932 0,07530396 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,0348932 0,07523749 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,0348932 0,07517114 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,0348932 0,07510491 ! androgen metabolic process GO:0008209 17 10 0,000 0,0348932 0,0750388 ! phospholipid efflux GO:0033700 19 10 0,000 0,0348932 0,0749728 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0348932 0,07490692 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,0348932 0,07484116 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,0348932 0,07477551 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,0348932 0,07470997 ! lung alveolus development GO:0048286 26 10 0,000 0,0348932 0,07464455 ! pathogenesis GO:0009405 17 10 0,000 0,0348932 0,07457925 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0348932 0,07451405 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,0348932 0,07444898 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,0348932 0,07438401 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,0348932 0,07431916 ! endoderm development GO:0007492 18 10 0,000 0,0348932 0,07425442 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,0348932 0,0741898 ! arginine catabolic process GO:0006527 17 10 0,000 0,0348932 0,07412529 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0348932 0,07406088 ! proline metabolic process GO:0006560 13 10 0,000 0,0348932 0,0739966 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0348932 0,07393242 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,0348932 0,07386835 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,0348932 0,0738044 ! V(D)J recombination GO:0033151 34 10 0,000 0,0348932 0,07374055 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,0348932 0,07367682 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,0348932 0,07361319 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,0348932 0,07354968 ! B cell proliferation GO:0042100 19 10 0,000 0,0348932 0,07348627 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,0348932 0,07342298 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,0348932 0,07335979 ! multicellular organism growth GO:0035264 19 10 0,000 0,0348932 0,07329671 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,0348932 0,07323374 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,0348932 0,07317088 ! ruffle organization GO:0031529 17 10 0,000 0,0348932 0,07310813 ! epithelial cell development GO:0002064 21 10 0,000 0,0348932 0,07304548 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,0348932 0,07298294 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0348932 0,07292051 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,0348932 0,07285819 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,0348932 0,07279597 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,0348932 0,07273386 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,0348932 0,07267185 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,0348932 0,07260995 ! motor axon guidance GO:0008045 22 10 0,000 0,0348932 0,07254815 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0348932 0,07248646 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0348932 0,07242488 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0348932 0,07236339 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0348932 0,07230202 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,0348932 0,07224074 ! segment specification GO:0007379 15 10 0,000 0,0348932 0,07217958 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,0348932 0,07211851 ! blastoderm segmentation GO:0007350 19 10 0,000 0,0348932 0,07205755 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,0348932 0,07199669 ! response to dsRNA GO:0043331 23 10 0,000 0,0348932 0,07193593 ! DNA ligation GO:0006266 18 10 0,000 0,0348932 0,07187528 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,0348932 0,07181472 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0348932 0,07175427 ! melanosome localization GO:0032400 16 10 0,000 0,0348932 0,07169393 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,0348932 0,07163368 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,0348932 0,07157353 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,0348932 0,07151349 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0348932 0,07145354 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,0348932 0,0713937 ! induction of an organ GO:0001759 17 10 0,000 0,0348932 0,07133396 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,0348932 0,07127431 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,0348932 0,07121477 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,0348932 0,07115532 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0348932 0,07109598 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0348932 0,07103673 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0348932 0,07097758 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,0348932 0,07091853 ! salivary gland development GO:0007431 28 10 0,000 0,0348932 0,07085958 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,0348932 0,07080073 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,0348932 0,07074197 ! midbrain development GO:0030901 14 10 0,000 0,0348932 0,07068332 ! musculoskeletal movement GO:0050881 16 10 0,000 0,0348932 0,07062475 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,0348932 0,07056629 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,0348932 0,07050792 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,0348932 0,07044965 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,0348932 0,07039148 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,0348932 0,0703334 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0348932 0,07027541 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0348932 0,07021753 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,0348932 0,07015974 ! detection of calcium ion GO:0005513 24 10 0,000 0,0348932 0,07010204 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0348932 0,07004444 ! blastocyst formation GO:0001825 18 10 0,000 0,0348932 0,06998693 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,0348932 0,06992951 ! cerebellar cortex development GO:0021695 16 10 0,000 0,0348932 0,0698722 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,0348932 0,06981497 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,0348932 0,06975784 ! response to nicotine GO:0035094 20 10 0,000 0,0348932 0,0697008 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,0348932 0,06964385 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0348932 0,069587 ! response to drug GO:0042493 149 83 1,000 0,03520529 0,07015214 ! response to oxygen levels GO:0070482 183 83 1,000 0,03520529 0,07009496 ! T cell activation GO:0042110 189 84 1,000 0,03598195 0,07158299 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,03676523 0,07308174 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03831537 0,07610117 ! respiratory burst GO:0045730 17 11 0,000 0,03831537 0,07603935 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03831537 0,07597763 ! neuron fate specification GO:0048665 18 11 0,000 0,03831537 0,07591601 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03831537 0,07585449 ! thyroid gland development GO:0030878 26 11 0,000 0,03831537 0,07579307 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,03831537 0,07573175 ! synapsis GO:0007129 14 11 0,000 0,03831537 0,07567053 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03831537 0,07560941 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03831537 0,07554838 ! response to pain GO:0048265 27 11 0,000 0,03831537 0,07548746 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03831537 0,07542663 ! blood vessel remodeling GO:0001974 30 11 0,000 0,03831537 0,0753659 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03831537 0,07530526 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,03831537 0,07524473 ! bone resorption GO:0045453 16 11 0,000 0,03831537 0,07518429 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03831537 0,07512395 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03831537 0,07506371 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03831537 0,07500356 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03831537 0,07494351 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03831537 0,07488356 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03831537 0,0748237 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03831537 0,07476393 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03831537 0,07470427 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03831537 0,07464469 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03831537 0,07458521 ! UV protection GO:0009650 20 11 0,000 0,03831537 0,07452583 ! adult heart development GO:0007512 16 11 0,000 0,03831537 0,07446654 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,03831537 0,07440735 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03831537 0,07434825 ! macroautophagy GO:0016236 19 11 0,000 0,03831537 0,07428924 ! temperature homeostasis GO:0001659 18 11 0,000 0,03831537 0,07423033 ! behavioral fear response GO:0001662 27 11 0,000 0,03831537 0,07417151 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03831537 0,07411278 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03831537 0,07405415 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03831537 0,07399561 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03831537 0,07393716 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03831537 0,0738788 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03831537 0,07382054 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03831537 0,07376237 ! regulation of organ growth GO:0046620 14 11 0,000 0,03831537 0,07370429 ! pigment granule localization GO:0051875 20 11 0,000 0,03831537 0,0736463 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03831537 0,0735884 ! vasoconstriction GO:0042310 20 11 0,000 0,03831537 0,07353059 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03831537 0,07347288 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03831537 0,07341525 ! embryonic axis specification GO:0000578 19 11 0,000 0,03831537 0,07335771 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03831537 0,07330027 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03831537 0,07324291 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03831537 0,07318565 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03831537 0,07312847 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03831537 0,07307139 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03831537 0,07301439 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03831537 0,07295748 ! prophase GO:0051324 17 11 0,000 0,03831537 0,07290066 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03831537 0,07284393 ! nucleosome positioning GO:0016584 15 11 0,000 0,03831537 0,07278728 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03831537 0,07273073 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03831537 0,07267426 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03831537 0,07261788 ! acid secretion GO:0046717 20 11 0,000 0,03831537 0,07256158 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03831537 0,07250538 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03831537 0,07244926 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,03831537 0,07239323 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03831537 0,07233728 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03831537 0,07228142 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03831537 0,07222565 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03831537 0,07216996 ! cholesterol efflux GO:0033344 21 11 0,000 0,03831537 0,07211436 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03831537 0,07205885 ! oocyte development GO:0048599 20 11 0,000 0,03831537 0,07200342 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,03831537 0,07194807 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,03831537 0,07189281 ! embryonic gut development GO:0048566 19 11 0,000 0,03831537 0,07183764 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03831537 0,07178255 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03831537 0,07172754 ! activation of innate immune response GO:0002218 16 11 0,000 0,03831537 0,07167262 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03831537 0,07161778 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03831537 0,07156303 ! lysogeny GO:0030069 22 11 0,000 0,03831537 0,07150836 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03831537 0,07145377 ! regulation of protein transport GO:0051223 165 87 1,000 0,03835138 0,07146638 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 167 88 1,000 0,03915415 0,07290669 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,04077879 0,07587402 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,0417255 0,07757641 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,0417255 0,07751741 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,0417255 0,07745851 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,0417255 0,0773997 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,0417255 0,07734097 ! protein complex disassembly GO:0043241 28 12 0,000 0,0417255 0,07728233 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0417255 0,07722379 ! hippocampus development GO:0021766 29 12 0,000 0,0417255 0,07716533 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,0417255 0,07710696 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,0417255 0,07704868 ! T cell proliferation GO:0042098 32 12 0,000 0,0417255 0,07699048 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0417255 0,07693238 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,0417255 0,07687436 ! ventral spinal cord development GO:0021517 25 12 0,000 0,0417255 0,07681643 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,0417255 0,07675858 ! drug transport GO:0015893 16 12 0,000 0,0417255 0,07670083 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,0417255 0,07664316 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,0417255 0,07658557 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,0417255 0,07652808 ! polyamine metabolic process GO:0006595 18 12 0,000 0,0417255 0,07647067 ! mitotic spindle organization GO:0007052 23 12 0,000 0,0417255 0,07641334 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,0417255 0,0763561 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,0417255 0,07629895 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,0417255 0,07624188 ! lipid digestion GO:0044241 21 12 0,000 0,0417255 0,0761849 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,0417255 0,07612801 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0417255 0,07607119 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,0417255 0,07601447 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,0417255 0,07595782 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0417255 0,07590127 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,0417255 0,07584479 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,0417255 0,0757884 ! snRNA metabolic process GO:0016073 30 12 0,000 0,0417255 0,07573209 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,0417255 0,07567587 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,0417255 0,07561973 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0417255 0,07556368 ! cranial nerve development GO:0021545 23 12 0,000 0,0417255 0,0755077 ! fucose catabolic process GO:0019317 25 12 0,000 0,0417255 0,07545181 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,0417255 0,07539601 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,0417255 0,07534028 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0417255 0,07528464 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,0417255 0,07522908 ! zymogen activation GO:0031638 18 12 0,000 0,0417255 0,0751736 ! T cell homeostasis GO:0043029 28 12 0,000 0,0417255 0,0751182 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,0417255 0,07506289 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,0417255 0,07500765 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,0417255 0,0749525 ! oocyte differentiation GO:0009994 21 12 0,000 0,0417255 0,07489743 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,0417255 0,07484244 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,0417255 0,07478753 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,0417255 0,0747327 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,0417255 0,07467795 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,0417255 0,07462328 ! defense response to fungus GO:0050832 15 12 0,000 0,0417255 0,07456869 ! developmental induction GO:0031128 22 12 0,000 0,0417255 0,07451418 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,0417255 0,07445975 ! lamellipodium assembly GO:0030032 24 12 0,000 0,0417255 0,0744054 ! response to cold GO:0009409 17 12 0,000 0,0417255 0,07435113 ! establishment of cell polarity GO:0030010 21 12 0,000 0,0417255 0,07429694 ! regulation of synapse organization GO:0050807 18 12 0,000 0,0417255 0,07424283 ! localization within membrane GO:0051668 26 12 0,000 0,0417255 0,07418879 ! positive regulation of MAP kinase activity GO:0043406 174 93 1,000 0,04326271 0,07686603 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,04410299 0,07830203 ! regulation of membrane potential GO:0042391 179 94 1,000 0,04410299 0,07824517 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04512364 0,07999786 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04512364 0,07993985 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04512364 0,07988192 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04512364 0,07982407 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04512364 0,07976631 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04512364 0,07970864 ! peroxisomal transport GO:0043574 28 13 0,000 0,04512364 0,07965105 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04512364 0,07959354 ! cartilage condensation GO:0001502 22 13 0,000 0,04512364 0,07953611 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04512364 0,07947877 ! organelle fusion GO:0048284 36 13 0,000 0,04512364 0,0794215 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04512364 0,07936432 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04512364 0,07930723 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04512364 0,07925021 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04512364 0,07919328 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,04512364 0,07913643 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04512364 0,07907966 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04512364 0,07902297 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04512364 0,07896637 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04512364 0,07890984 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04512364 0,0788534 ! methionine metabolic process GO:0006555 31 13 0,000 0,04512364 0,07879703 ! plasma membrane organization GO:0007009 27 13 0,000 0,04512364 0,07874075 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04512364 0,07868454 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04512364 0,07862842 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04512364 0,07857238 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04512364 0,07851642 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,04512364 0,07846053 ! cytokine metabolic process GO:0042107 24 13 0,000 0,04512364 0,07840473 ! exocrine system development GO:0035272 34 13 0,000 0,04512364 0,078349 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,04512364 0,07829336 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,04512364 0,07823779 ! L-glutamate transport GO:0015813 30 13 0,000 0,04512364 0,0781823 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,04512364 0,07812689 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04512364 0,07807156 ! protein homotetramerization GO:0051289 24 13 0,000 0,04512364 0,07801631 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04512364 0,07796114 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04512364 0,07790604 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04512364 0,07785102 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04512364 0,07779608 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04512364 0,07774122 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04512364 0,07768643 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,04512364 0,07763172 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04512364 0,07757709 ! histone methylation GO:0016571 29 13 0,000 0,04512364 0,07752254 ! chromatin silencing GO:0006342 29 13 0,000 0,04512364 0,07746806 ! gland morphogenesis GO:0022612 31 13 0,000 0,04512364 0,07741366 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04512364 0,07735933 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04512364 0,07730508 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04512364 0,07725091 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04512364 0,07719681 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04512364 0,07714279 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04512364 0,07708884 ! spleen development GO:0048536 24 13 0,000 0,04512364 0,07703497 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,04512364 0,07698118 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,04512364 0,07692746 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04512364 0,07687381 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04512364 0,07682024 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04512364 0,07676675 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04512364 0,07671332 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04512364 0,07665998 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04512364 0,0766067 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04512364 0,07655351 ! insulin secretion GO:0030073 24 13 0,000 0,04512364 0,07650038 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04512364 0,07644733 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04512364 0,07639435 ! acrosome reaction GO:0007340 19 13 0,000 0,04512364 0,07634145 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04512364 0,07628861 ! transcription initiation GO:0006352 171 97 1,000 0,04666 0,07883152 ! regulation of protein localization GO:0032880 188 97 1,000 0,04666 0,07877704 ! forebrain development GO:0030900 210 98 1,000 0,04752422 0,08018071 ! rRNA transcription GO:0009303 28 14 0,000 0,04850982 0,08178709 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,04850982 0,08173068 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,04850982 0,08167435 ! water transport GO:0006833 21 14 0,000 0,04850982 0,08161811 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,04850982 0,08156193 ! non-recombinational repair GO:0000726 29 14 0,000 0,04850982 0,08150584 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,04850982 0,08144982 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,04850982 0,08139388 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,04850982 0,08133802 ! RNA polyadenylation GO:0043631 32 14 0,000 0,04850982 0,08128223 ! lipid localization GO:0010876 32 14 0,000 0,04850982 0,08122652 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,04850982 0,08117088 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,04850982 0,08111532 ! regulated secretory pathway GO:0045055 24 14 0,000 0,04850982 0,08105984 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,04850982 0,08100444 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,04850982 0,0809491 ! arginine metabolic process GO:0006525 21 14 0,000 0,04850982 0,08089385 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,04850982 0,08083867 ! regulation of heart rate GO:0002027 25 14 0,000 0,04850982 0,08078356 ! fear response GO:0042596 34 14 0,000 0,04850982 0,08072853 ! organic alcohol transport GO:0015850 29 14 0,000 0,04850982 0,08067358 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,04850982 0,0806187 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,04850982 0,08056389 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04850982 0,08050916 ! neutral amino acid transport GO:0015804 28 14 0,000 0,04850982 0,08045451 ! bone mineralization GO:0030282 18 14 0,000 0,04850982 0,08039992 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,04850982 0,08034542 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,04850982 0,08029098 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,04850982 0,08023662 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,04850982 0,08018233 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,04850982 0,08012812 ! regulation of cellular pH GO:0030641 27 14 0,000 0,04850982 0,08007398 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,04850982 0,08001991 ! ribosome assembly GO:0042255 18 14 0,000 0,04850982 0,07996592 ! cerebellum development GO:0021549 23 14 0,000 0,04850982 0,079912 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,04850982 0,07985815 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,04850982 0,07980437 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,04850982 0,07975067 ! response to gamma radiation GO:0010332 30 14 0,000 0,04850982 0,07969703 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,04850982 0,07964347 ! NADP metabolic process GO:0006739 24 14 0,000 0,04850982 0,07958999 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,04850982 0,07953657 ! oxygen transport GO:0015671 22 14 0,000 0,04850982 0,07948323 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04850982 0,07942995 ! male genitalia development GO:0030539 26 14 0,000 0,04850982 0,07937675 ! regulation of RNA stability GO:0043487 33 14 0,000 0,04850982 0,07932362 ! regulation of axon extension GO:0030516 43 14 0,000 0,04850982 0,07927056 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,04850982 0,07921757 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,04850982 0,07916466 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,04927018 0,08035183 GO:0060538|skeletal muscle organ development, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05188409 0,08455826 ! lactation GO:0007595 30 15 0,000 0,05188409 0,08450188 ! reproductive cellular process GO:0048610 22 15 0,000 0,05188409 0,08444559 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05188409 0,08438937 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05188409 0,08433322 ! superoxide anion generation GO:0042554 22 15 0,000 0,05188409 0,08427715 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05188409 0,08422115 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,05188409 0,08416522 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05188409 0,08410937 ! copper ion transport GO:0006825 22 15 0,000 0,05188409 0,0840536 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05188409 0,0839979 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05188409 0,08394227 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05188409 0,08388672 ! sulfate transport GO:0008272 27 15 0,000 0,05188409 0,08383123 ! response to cAMP GO:0051591 25 15 0,000 0,05188409 0,08377583 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05188409 0,08372049 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05188409 0,08366523 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,05188409 0,08361004 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05188409 0,08355493 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05188409 0,08349989 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,05188409 0,08344492 ! vesicle coating GO:0006901 38 15 0,000 0,05188409 0,08339002 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05188409 0,08333519 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05188409 0,08328044 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,05188409 0,08322576 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05188409 0,08317115 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05188409 0,08311661 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,05188409 0,08306214 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05188409 0,08300775 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05188409 0,08295342 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05188409 0,08289917 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05188409 0,08284499 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05188409 0,08279087 ! histone deacetylation GO:0016575 24 15 0,000 0,05188409 0,08273683 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05188409 0,08268286 ! water homeostasis GO:0030104 28 15 0,000 0,05188409 0,08262896 ! cofactor transport GO:0051181 30 15 0,000 0,05188409 0,08257513 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05188409 0,08252137 ! muscle maintenance GO:0046716 26 15 0,000 0,05188409 0,08246768 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05188409 0,08241406 ! intestinal absorption GO:0050892 31 15 0,000 0,05188409 0,08236051 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05188409 0,08230703 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05188409 0,08225362 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05188409 0,08220028 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,05188409 0,082147 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,05188409 0,0820938 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05188409 0,08204066 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05188409 0,0819876 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05188409 0,0819346 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05188409 0,08188167 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05524649 0,0871318 ! positive regulation of cell size GO:0045793 29 16 0,000 0,05524649 0,08707559 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05524649 0,08701945 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05524649 0,08696338 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05524649 0,08690738 ! bone remodeling GO:0046849 28 16 0,000 0,05524649 0,08685146 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,05524649 0,0867956 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05524649 0,08673982 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05524649 0,08668411 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05524649 0,08662847 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05524649 0,08657291 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05524649 0,08651741 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05524649 0,08646199 ! startle response GO:0001964 28 16 0,000 0,05524649 0,08640663 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05524649 0,08635135 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05524649 0,08629614 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05524649 0,086241 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05524649 0,08618593 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05524649 0,08613093 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05524649 0,086076 ! response to osmotic stress GO:0006970 27 16 0,000 0,05524649 0,08602114 ! lysosomal transport GO:0007041 31 16 0,000 0,05524649 0,08596635 ! fructose metabolic process GO:0006000 25 16 0,000 0,05524649 0,08591163 ! L-amino acid transport GO:0015807 33 16 0,000 0,05524649 0,08585697 ! stem cell development GO:0048864 46 16 0,000 0,05524649 0,08580239 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05524649 0,08574788 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05524649 0,08569344 ! intermediate filament-based process GO:0045103 36 16 0,000 0,05524649 0,08563906 ! negative regulation of immune response GO:0050777 38 16 0,000 0,05524649 0,08558476 ! axon cargo transport GO:0008088 46 16 0,000 0,05524649 0,08553052 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05524649 0,08547635 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05524649 0,08542226 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,05524649 0,08536822 ! DNA replication initiation GO:0006270 28 16 0,000 0,05524649 0,08531426 ! neuron recognition GO:0008038 40 16 0,000 0,05524649 0,08526037 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05524649 0,08520654 ! tissue regeneration GO:0042246 27 16 0,000 0,05524649 0,08515278 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05524649 0,08509909 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05524649 0,08504547 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,05524649 0,08499192 ! biomineral formation GO:0031214 22 16 0,000 0,05524649 0,08493843 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05524649 0,08488501 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05524649 0,08483166 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05524649 0,08477837 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05524649 0,08472515 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05524649 0,084672 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05524649 0,08461891 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05524649 0,08456589 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05524649 0,08451294 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,05524649 0,08446005 ! peptide hormone processing GO:0016486 27 16 0,000 0,05524649 0,08440723 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,05859705 0,08947037 ! metencephalon development GO:0022037 32 17 0,000 0,05859705 0,08941449 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,05859705 0,08935868 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,05859705 0,08930293 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,05859705 0,08924726 ! signal complex assembly GO:0007172 47 17 0,000 0,05859705 0,08919165 ! endothelial cell migration GO:0043542 31 17 0,000 0,05859705 0,08913611 ! gene silencing by RNA GO:0031047 38 17 0,000 0,05859705 0,08908065 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,05859705 0,08902525 ! glial cell development GO:0021782 28 17 0,000 0,05859705 0,08896992 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,05859705 0,08891466 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,05859705 0,08885947 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,05859705 0,08880434 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,05859705 0,08874929 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,05859705 0,0886943 ! myoblast differentiation GO:0045445 50 17 0,000 0,05859705 0,08863938 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,05859705 0,08858453 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,05859705 0,08852975 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,05859705 0,08847503 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,05859705 0,08842038 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,05859705 0,0883658 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,05859705 0,08831129 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,05859705 0,08825684 ! membrane budding GO:0006900 42 17 0,000 0,05859705 0,08820246 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,05859705 0,08814815 ! regulation of protein binding GO:0043393 33 17 0,000 0,05859705 0,08809391 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,05859705 0,08803973 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,05859705 0,08798562 ! genitalia development GO:0048806 32 17 0,000 0,05859705 0,08793157 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,05859705 0,08787759 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,05859705 0,08782368 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,05859705 0,08776983 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,05859705 0,08771605 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,05859705 0,08766234 ! steroid catabolic process GO:0006706 34 17 0,000 0,05859705 0,08760869 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,05859705 0,08755511 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,05859705 0,08750159 ! gas transport GO:0015669 26 17 0,000 0,05859705 0,08744814 ! organic cation transport GO:0015695 32 17 0,000 0,05859705 0,08739475 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,05859705 0,08734143 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,05859705 0,08728817 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06193583 0,0922055 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06193583 0,09214935 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06193583 0,09209326 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06193583 0,09203725 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06193583 0,0919813 ! adult walking behavior GO:0007628 36 18 0,000 0,06193583 0,09192542 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06193583 0,0918696 ! heart looping GO:0001947 34 18 0,000 0,06193583 0,09181386 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06193583 0,09175818 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,06193583 0,09170257 ! centrosome cycle GO:0007098 26 18 0,000 0,06193583 0,09164702 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06193583 0,09159155 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06193583 0,09153614 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,06193583 0,09148079 ! glycine metabolic process GO:0006544 30 18 0,000 0,06193583 0,09142552 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06193583 0,09137031 ! response to retinoic acid GO:0032526 31 18 0,000 0,06193583 0,09131517 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06193583 0,09126009 ! DNA integration GO:0015074 32 18 0,000 0,06193583 0,09120508 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,06193583 0,09115014 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06193583 0,09109526 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06193583 0,09104045 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,06193583 0,09098571 ! neural crest cell migration GO:0001755 41 18 0,000 0,06193583 0,09093103 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06193583 0,09087642 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06193583 0,09082187 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06193583 0,09076739 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06193583 0,09071297 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,06193583 0,09065862 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,06193583 0,09060433 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06193583 0,09055011 ! detection of bacterium GO:0016045 22 18 0,000 0,06193583 0,09049595 ! nerve development GO:0021675 34 18 0,000 0,06193583 0,09044186 ! defense response to virus GO:0051607 43 18 0,000 0,06193583 0,09038783 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06193583 0,09033387 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,06193583 0,09027997 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06526286 0,09507285 ! positive regulation of translation GO:0045727 31 19 0,000 0,06526286 0,09501619 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06526286 0,0949596 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,06526286 0,09490308 ! neuron maturation GO:0042551 46 19 0,000 0,06526286 0,09484662 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,06526286 0,09479023 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06526286 0,09473391 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06526286 0,09467765 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06526286 0,09462147 ! inositol metabolic process GO:0006020 33 19 0,000 0,06526286 0,09456534 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06526286 0,09450929 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06526286 0,0944533 ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06526286 0,09439738 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,06526286 0,09434152 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,06526286 0,09428573 ! cerebral cortex development GO:0021987 40 19 0,000 0,06526286 0,09423001 ! pigmentation during development GO:0048066 42 19 0,000 0,06526286 0,09417435 ! response to vitamin A GO:0033189 32 19 0,000 0,06526286 0,09411875 ! heme metabolic process GO:0042168 40 19 0,000 0,06526286 0,09406323 ! neuromuscular junction development GO:0007528 43 19 0,000 0,06526286 0,09400776 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,06526286 0,09395237 ! response to fungus GO:0009620 26 19 0,000 0,06526286 0,09389704 ! heart process GO:0003015 32 19 0,000 0,06526286 0,09384177 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,06526286 0,09378657 ! visual learning GO:0008542 38 19 0,000 0,06526286 0,09373143 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06526286 0,09367636 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06526286 0,09362136 ! vitamin transport GO:0051180 31 19 0,000 0,06526286 0,09356641 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06526286 0,09351154 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06526286 0,09345672 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,06526286 0,09340197 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,06526286 0,09334729 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,06526286 0,09329267 ! cilium assembly GO:0042384 38 19 0,000 0,06526286 0,09323811 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06526286 0,09318362 ! protein secretion GO:0009306 45 20 0,000 0,06857818 0,09786011 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,06857818 0,09780298 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,06857818 0,09774592 ! positive regulation of ossification GO:0045778 50 20 0,000 0,06857818 0,09768892 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,06857818 0,097632 ! skin development GO:0043588 42 20 0,000 0,06857818 0,09757513 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,06857818 0,09751834 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,06857818 0,09746161 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,06857818 0,09740494 ! response to vitamin GO:0033273 36 20 0,000 0,06857818 0,09734835 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,06857818 0,09729181 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,06857818 0,09723535 ! bile acid metabolic process GO:0008206 34 20 0,000 0,06857818 0,09717895 ! retinoid metabolic process GO:0001523 34 20 0,000 0,06857818 0,09712261 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,06857818 0,09706634 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,06857818 0,09701014 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,06857818 0,096954 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,06857818 0,09689792 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,06857818 0,09684191 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,06857818 0,09678596 ! peptide secretion GO:0002790 38 20 0,000 0,06857818 0,09673008 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,06857818 0,09667427 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,06857818 0,09661851 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,06857818 0,09656283 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,06857818 0,0965072 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,06857818 0,09645164 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,06857818 0,09639615 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,06857818 0,09634072 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,06857818 0,09628535 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,06857818 0,09623004 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,06857818 0,0961748 ! regulation of glucose import GO:0046324 30 20 0,000 0,06857818 0,09611962 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,06857818 0,09606451 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,06857818 0,09600946 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,06857818 0,09595447 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,06857818 0,09589954 ! regulation of cell killing GO:0031341 46 21 0,000 0,07188184 0,10046187 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,07188184 0,10040443 ! hormone secretion GO:0046879 39 21 0,000 0,07188184 0,10034705 ! cAMP metabolic process GO:0046058 41 21 0,000 0,07188184 0,10028974 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,07188184 0,1002325 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,07188184 0,10017532 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,07188184 0,10011821 ! ovarian follicle development GO:0001541 39 21 0,000 0,07188184 0,10006116 ! smooth muscle contraction GO:0006939 48 21 0,000 0,07188184 0,10000418 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,07188184 0,09994726 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,07188184 0,09989041 ! plasma membrane fusion GO:0045026 33 21 0,000 0,07188184 0,09983362 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,07188184 0,0997769 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,07188184 0,09972024 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,07188184 0,09966364 ! sensory perception of pain GO:0019233 33 21 0,000 0,07188184 0,09960711 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,07188184 0,09955065 ! collagen fibril organization GO:0030199 62 21 0,000 0,07188184 0,09949424 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,07188184 0,09943791 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,07188184 0,09938163 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,07188184 0,09932542 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,07188184 0,09926927 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,07188184 0,09921319 ! collagen catabolic process GO:0030574 29 21 0,000 0,07188184 0,09915717 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,07188184 0,09910121 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,07188184 0,09904531 ! sperm-egg recognition GO:0035036 23 21 0,000 0,07188184 0,09898948 ! actin filament-based movement GO:0030048 47 21 0,000 0,07188184 0,09893371 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,07188184 0,09887801 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,07517388 0,10334822 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,07517388 0,10329009 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,07517388 0,10323203 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,07517388 0,10317403 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,07517388 0,1031161 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,07517388 0,10305824 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,07517388 0,10300044 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,07517388 0,1029427 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,07517388 0,10288503 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,07517388 0,10282742 ! cellular response to starvation GO:0009267 37 22 0,000 0,07517388 0,10276988 ! vacuolar transport GO:0007034 41 22 0,000 0,07517388 0,1027124 ! central nervous system neuron development GO:0021954 47 22 0,000 0,07517388 0,10265499 ! fucose metabolic process GO:0006004 44 22 0,000 0,07517388 0,10259764 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,07517388 0,10254036 ! ureteric bud development GO:0001657 50 22 0,000 0,07517388 0,10248314 ! stem cell differentiation GO:0048863 57 22 0,000 0,07517388 0,10242598 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,07517388 0,10236888 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,07517388 0,10231185 ! renal system process GO:0003014 42 22 0,000 0,07517388 0,10225489 ! vasodilation GO:0042311 40 22 0,000 0,07517388 0,10219798 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,07517388 0,10214114 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,07517388 0,10208437 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,07517388 0,10202765 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,07517388 0,101971 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,07517388 0,10191442 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,07517388 0,10185789 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,07517388 0,10180143 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,07517388 0,10174503 ! sarcomere organization GO:0045214 32 22 0,000 0,07517388 0,10168869 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,07517388 0,10163242 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,07517388 0,1015762 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,07517388 0,10152005 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,07517388 0,10146397 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,07517388 0,10140794 ! gut development GO:0048565 44 22 0,000 0,07517388 0,10135197 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,07517388 0,10129607 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,07517388 0,10124023 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,07517388 0,10118445 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,07845432 0,1055418 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,07845432 0,10548372 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,07845432 0,1054257 ! glycerol metabolic process GO:0006071 40 23 0,000 0,07845432 0,10536774 ! viral genome replication GO:0019079 44 23 0,000 0,07845432 0,10530984 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,07845432 0,10525201 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,07845432 0,10519424 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,07845432 0,10513654 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,07845432 0,1050789 ! regeneration GO:0031099 42 23 0,000 0,07845432 0,10502132 ! axis specification GO:0009798 43 23 0,000 0,07845432 0,10496381 ! visual behavior GO:0007632 46 23 0,000 0,07845432 0,10490636 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,07845432 0,10484897 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,07845432 0,10479164 ! response to ethanol GO:0045471 47 23 0,000 0,07845432 0,10473438 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,07845432 0,10467718 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,07845432 0,10462004 ! peroxisome organization GO:0007031 43 23 0,000 0,07845432 0,10456296 ! lysosome organization GO:0007040 47 23 0,000 0,07845432 0,10450595 ! vesicle targeting GO:0006903 49 23 0,000 0,07845432 0,104449 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,07845432 0,10439211 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,07845432 0,10433528 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,07845432 0,10427852 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,07845432 0,10422181 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,07845432 0,10416517 ! fatty acid transport GO:0015908 47 23 0,000 0,07845432 0,10410859 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,07845432 0,10405207 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,07845432 0,10399561 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,07845432 0,10393922 ! hormone transport GO:0009914 41 23 0,000 0,07845432 0,10388288 ! cell-cell recognition GO:0009988 28 23 0,000 0,07845432 0,10382661 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,07845432 0,10377039 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,07845432 0,10371424 GO:0006099|tricarboxylic acid cycle, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,08172323 0,1079772 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,08172323 0,10791884 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,08172323 0,10786053 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,08172323 0,10780229 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,08172323 0,10774412 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,08172323 0,107686 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,08172323 0,10762795 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,08172323 0,10756996 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,08172323 0,10751203 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,08172323 0,10745417 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,08172323 0,10739637 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,08172323 0,10733863 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,08172323 0,10728095 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,08172323 0,10722333 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,08172323 0,10716578 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,08172323 0,10710829 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 52 24 0,000 0,08172323 0,10705086 ! leukotriene metabolic process GO:0006691 47 24 0,000 0,08172323 0,10699349 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,08172323 0,10693618 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,08172323 0,10687893 ! membrane depolarization GO:0051899 45 24 0,000 0,08172323 0,10682175 ! pallium development GO:0021543 56 24 0,000 0,08172323 0,10676462 ! oogenesis GO:0048477 44 24 0,000 0,08172323 0,10670756 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,08172323 0,10665056 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,08172323 0,10659362 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,08172323 0,10653674 ! platelet activation GO:0030168 41 24 0,000 0,08172323 0,10647992 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,08172323 0,10642316 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,08172323 0,10636646 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,08172323 0,10630982 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,08172323 0,10625325 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,08172323 0,10619673 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,08172323 0,10614027 ! regulation of amine transport GO:0051952 41 24 0,000 0,08172323 0,10608387 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,08172323 0,10602753 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,08498063 0,11019516 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,08498063 0,1101367 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,08498063 0,1100783 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,08498063 0,11001997 ! leukocyte adhesion GO:0007159 55 25 0,000 0,08498063 0,10996169 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,08498063 0,10990348 ! phototransduction GO:0007602 37 25 0,000 0,08498063 0,10984533 ! vasculogenesis GO:0001570 49 25 0,000 0,08498063 0,10978724 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,08498063 0,10972922 ! vacuole organization GO:0007033 49 25 0,000 0,08498063 0,10967125 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,08498063 0,10961335 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,08498063 0,1095555 ! receptor metabolic process GO:0043112 53 25 0,000 0,08498063 0,10949772 ! chromosome condensation GO:0030261 48 25 0,000 0,08498063 0,10944 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,08498063 0,10938234 ! regulation of behavior GO:0050795 48 25 0,000 0,08498063 0,10932474 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,08498063 0,1092672 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,08498063 0,10920972 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,08498063 0,1091523 ! immunoglobulin production GO:0002377 62 25 0,000 0,08498063 0,10909494 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,08498063 0,10903765 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,08498063 0,10898041 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,08498063 0,10892323 ! liver development GO:0001889 55 25 0,000 0,08498063 0,10886611 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,08822657 0,11296515 ! myelination GO:0042552 50 26 0,000 0,08822657 0,11290597 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,08822657 0,11284686 ! molting cycle process GO:0022404 52 26 0,000 0,08822657 0,11278781 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,08822657 0,11272882 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,08822657 0,11266989 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,08822657 0,11261102 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,08822657 0,11255222 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,08822657 0,11249348 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,08822657 0,11243479 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,08822657 0,11237617 ! digestive system process GO:0022600 49 26 0,000 0,08822657 0,11231761 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,08822657 0,11225912 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 0,000 0,08822657 0,11220068 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,08822657 0,1121423 ! osteoblast differentiation GO:0001649 63 26 0,000 0,08822657 0,11208398 ! neural crest cell development GO:0014032 59 26 0,000 0,08822657 0,11202573 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,08822657 0,11196753 ! negative regulation of cell development GO:0010721 83 26 0,000 0,08822657 0,1119094 GO:0050768|negative regulation of neurogenesis, ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,08822657 0,11185132 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,08822657 0,11179331 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,08822657 0,11173536 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,08822657 0,11167746 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,08822657 0,11161963 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,08822657 0,11156185 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,08822657 0,11150414 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,08822657 0,11144648 ! blastocyst development GO:0001824 50 26 0,000 0,08822657 0,11138889 ! telomere organization GO:0032200 46 26 0,000 0,08822657 0,11133135 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,08822657 0,11127388 ! neural tube closure GO:0001843 58 26 0,000 0,08822657 0,11121646 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,08822657 0,1111591 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,08822657 0,11110181 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,08822657 0,11104457 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,09146108 0,11505634 ! embryonic pattern specification GO:0009880 49 27 0,000 0,09146108 0,11499713 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,09146108 0,11493797 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,09146108 0,11487888 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,09146108 0,11481985 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,09146108 0,11476087 ! iron ion transport GO:0006826 65 27 0,000 0,09146108 0,11470196 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,09146108 0,11464311 ! superoxide metabolic process GO:0006801 41 27 0,000 0,09146108 0,11458432 ! tube lumen formation GO:0035148 59 27 0,000 0,09146108 0,11452559 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,09146108 0,11446692 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,09146108 0,1144083 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,09146108 0,11434975 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,09146108 0,11429126 ! response to starvation GO:0042594 47 27 0,000 0,09146108 0,11423283 ! response to toxin GO:0009636 49 27 0,000 0,09146108 0,11417446 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,09146108 0,11411615 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,09146108 0,1140579 ! leukocyte proliferation GO:0070661 59 27 0,000 0,09146108 0,1139997 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,09146108 0,11394157 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,09468421 0,1178968 ! neuron fate commitment GO:0048663 52 28 0,000 0,09468421 0,11783674 ! vesicle docking GO:0048278 55 28 0,000 0,09468421 0,11777674 ! circadian rhythm GO:0007623 56 28 0,000 0,09468421 0,11771681 ! dendrite development GO:0016358 67 28 0,000 0,09468421 0,11765693 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,09468421 0,11759711 ! fat cell differentiation GO:0045444 57 28 0,000 0,09468421 0,11753736 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,09468421 0,11747767 ! sperm motility GO:0030317 37 28 0,000 0,09468421 0,11741803 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,09468421 0,11735846 ! base-excision repair GO:0006284 41 28 0,000 0,09468421 0,11729895 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,09468421 0,1172395 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,09468421 0,1171801 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,09468421 0,11712077 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,09468421 0,1170615 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,09468421 0,11700229 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,09468421 0,11694314 ! glutathione metabolic process GO:0006749 42 28 0,000 0,09468421 0,11688404 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,09468421 0,11682501 ! lipid oxidation GO:0034440 48 28 0,000 0,09468421 0,11676604 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,09468421 0,11670713 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,09468421 0,11664827 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,097896 0,12054431 ! translational initiation GO:0006413 66 29 0,000 0,097896 0,12048359 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,097896 0,12042292 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,097896 0,12036231 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,097896 0,12030177 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,097896 0,12024129 ! primary neural tube formation GO:0014020 61 29 0,000 0,097896 0,12018086 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,097896 0,1201205 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,097896 0,1200602 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,097896 0,11999996 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,097896 0,11993978 ! synaptogenesis GO:0007416 46 29 0,000 0,097896 0,11987966 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,097896 0,1198196 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,097896 0,1197596 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,097896 0,11969966 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,10109648 0,12355112 ! phenol metabolic process GO:0018958 56 30 0,000 0,10109648 0,12348935 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,10109648 0,12342763 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,10109648 0,12336598 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,10109648 0,12330439 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,10109648 0,12324286 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,10109648 0,12318139 ! myofibril assembly GO:0030239 50 30 0,000 0,10109648 0,12311999 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,10109648 0,12305864 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,10109648 0,12299736 ! cell fate determination GO:0001709 64 30 0,000 0,10109648 0,12293613 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,10109648 0,12287497 ! phospholipid transport GO:0015914 65 30 0,000 0,10109648 0,12281387 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,10109648 0,12275283 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,10109648 0,12269185 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,10109648 0,12263093 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,10109648 0,12257007 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,10109648 0,12250927 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,10109648 0,12244853 ! regulation of coagulation GO:0050818 52 30 0,000 0,10109648 0,12238786 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,10428569 0,12618621 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,10428569 0,12612374 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,10428569 0,12606133 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,10428569 0,12599899 ! regulation of innate immune response GO:0045088 57 31 0,000 0,10428569 0,1259367 ! peptide transport GO:0015833 60 31 0,000 0,10428569 0,12587448 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,10428569 0,12581232 ! detection of light stimulus GO:0009583 44 31 0,000 0,10428569 0,12575022 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,10428569 0,12568818 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,10428569 0,12562621 ! natural killer cell activation GO:0030101 50 31 0,000 0,10428569 0,12556429 ! ensheathment of neurons GO:0007272 64 31 0,000 0,10428569 0,12550244 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,10428569 0,12544065 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,10428569 0,12537891 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,10428569 0,12531724 ! eye morphogenesis GO:0048592 65 31 0,000 0,10428569 0,12525563 ! response to heat GO:0009408 54 31 0,000 0,10428569 0,12519408 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,10428569 0,12513259 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,10746369 0,12888256 ! collagen metabolic process GO:0032963 49 32 0,000 0,10746369 0,12881932 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,10746369 0,12875615 ! spindle organization GO:0007051 50 32 0,000 0,10746369 0,12869303 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,10746369 0,12862998 ! metanephros development GO:0001656 81 32 0,000 0,10746369 0,12856699 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,10746369 0,12850405 ! muscle cell development GO:0055001 52 32 0,000 0,10746369 0,12844119 ! mesoderm formation GO:0001707 73 32 0,000 0,10746369 0,12837838 ! peripheral nervous system development GO:0007422 68 32 0,000 0,10746369 0,12831563 ! BMP signaling pathway GO:0030509 71 32 0,000 0,10746369 0,12825295 ! hindbrain development GO:0030902 65 32 0,000 0,10746369 0,12819032 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,10746369 0,12812776 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,10746369 0,12806526 ! gene silencing GO:0016458 71 32 0,000 0,10746369 0,12800282 ! regulation of pH GO:0006885 56 33 0,000 0,11063049 0,13171067 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,11063049 0,13164651 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,11063049 0,13158242 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,11063049 0,13151839 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,11063049 0,13145442 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,11063049 0,13139051 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,11063049 0,13132667 ! response to ionizing radiation GO:0010212 74 33 0,000 0,11063049 0,13126289 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,11063049 0,13119917 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,11063049 0,13113551 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,11063049 0,13107191 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,11063049 0,13100838 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,11063049 0,13094491 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,11063049 0,1308815 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,11063049 0,13081815 ! glial cell differentiation GO:0010001 67 34 0,000 0,11378615 0,13448455 ! post-embryonic development GO:0009791 76 34 0,000 0,11378615 0,13441952 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,11378615 0,13435455 ! cholesterol transport GO:0030301 62 34 0,000 0,11378615 0,13428964 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,11378615 0,1342248 ! spliceosome assembly GO:0000245 75 34 0,000 0,11378615 0,13416002 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,11378615 0,1340953 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,11378615 0,13403065 ! formation of primary germ layer GO:0001704 76 34 0,000 0,11378615 0,13396605 ! cell fate specification GO:0001708 56 34 0,000 0,11378615 0,13390152 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,11378615 0,13383705 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,11378615 0,13377265 ! adult locomotory behavior GO:0008344 62 34 0,000 0,11378615 0,1337083 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,1169307 0,13733735 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,1169307 0,13727136 ! negative regulation of secretion GO:0051048 68 35 0,000 0,1169307 0,13720542 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,1169307 0,13713956 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,1169307 0,13707375 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,1169307 0,13700801 ! membrane docking GO:0022406 69 35 0,000 0,1169307 0,13694233 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,1169307 0,13687671 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,1169307 0,13681116 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,1169307 0,13674566 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,1169307 0,13668024 ! ceramide metabolic process GO:0006672 72 35 0,000 0,1169307 0,13661487 ! telencephalon development GO:0021537 81 35 0,000 0,1169307 0,13654957 ! sterol transport GO:0015918 63 35 0,000 0,1169307 0,13648433 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,1169307 0,13641915 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,1169307 0,13635403 ! placenta development GO:0001890 53 35 0,000 0,1169307 0,13628898 ! vesicle localization GO:0051648 70 35 0,000 0,1169307 0,13622398 ! regulation of muscle development GO:0048634 82 36 0,000 0,12006418 0,13980781 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,12006418 0,1397412 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,12006418 0,13967466 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,12006418 0,13960818 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,12006418 0,13954176 ! positive regulation of cell development GO:0010720 85 36 0,000 0,12006418 0,13947541 ! protein targeting to membrane GO:0006612 75 36 0,000 0,12006418 0,13940912 ! regulation of proteolysis GO:0030162 77 36 0,000 0,12006418 0,13934289 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,12006418 0,13927673 ! aerobic respiration GO:0009060 56 36 0,000 0,12006418 0,13921062 ! cytokine production GO:0001816 68 36 0,000 0,12006418 0,13914458 ! embryonic organ development GO:0048568 67 36 0,000 0,12006418 0,13907861 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,12006418 0,13901269 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,12318663 0,14256036 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,12318663 0,14249286 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,12318663 0,14242543 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,12318663 0,14235805 ! sister chromatid segregation GO:0000819 65 37 0,000 0,12318663 0,14229075 ! odontogenesis GO:0042476 74 37 0,000 0,12318663 0,1422235 ! actomyosin structure organization GO:0031032 68 37 0,000 0,12318663 0,14215632 ! tissue remodeling GO:0048771 78 37 0,000 0,12318663 0,1420892 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,12318663 0,14202215 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,12318663 0,14195515 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,12318663 0,14188823 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,12318663 0,14182136 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,12629808 0,145335 ! meiosis I GO:0007127 74 38 0,000 0,12629808 0,14526658 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,12629808 0,14519822 ! organic anion transport GO:0015711 82 38 0,000 0,12629808 0,14512992 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,12629808 0,14506169 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,12629808 0,14499352 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,12629808 0,14492542 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,12629808 0,14485738 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,12629808 0,1447894 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,12629808 0,14472149 ! spermatid development GO:0007286 69 38 0,000 0,12629808 0,14465364 ! pigment metabolic process GO:0042440 87 38 0,000 0,12629808 0,14458586 ! neural tube formation GO:0001841 79 38 0,000 0,12629808 0,14451813 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,12939858 0,1479966 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,12939858 0,14792735 ! negative regulation of binding GO:0051100 71 39 0,000 0,12939858 0,14785816 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,12939858 0,14778903 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,12939858 0,14771997 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,12939858 0,14765098 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,12939858 0,14758205 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,12939858 0,14751318 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,12939858 0,14744438 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,12939858 0,14737564 ! mammary gland development GO:0030879 93 40 0,000 0,13248817 0,15082414 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,13248817 0,15075389 ! lipid homeostasis GO:0055088 75 40 0,000 0,13248817 0,15068371 ! mismatch repair GO:0006298 58 40 0,000 0,13248817 0,15061359 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,13248817 0,15054354 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,13248817 0,15047355 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,13248817 0,15040363 ! mRNA catabolic process GO:0006402 79 41 0,000 0,13556688 0,15382717 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,13556688 0,15375575 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,13556688 0,1536844 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,13556688 0,15361312 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,13556688 0,15354191 ! gliogenesis GO:0042063 91 41 0,000 0,13556688 0,15347076 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,13556688 0,15339967 ! mesenchymal cell development GO:0014031 94 41 0,000 0,13556688 0,15332865 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,13556688 0,1532577 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,13556688 0,15318681 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,13556688 0,15311599 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,13556688 0,15304524 ! RNA modification GO:0009451 64 41 0,000 0,13556688 0,15297454 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,13863475 0,15636413 ! organic ether metabolic process GO:0018904 59 42 0,000 0,13863475 0,15629197 ! T cell differentiation GO:0030217 93 42 0,000 0,13863475 0,15621988 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,13863475 0,15614785 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,13863475 0,1560759 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,13863475 0,15600401 ! regulation of protein secretion GO:0050708 77 42 0,000 0,13863475 0,15593218 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,13863475 0,15586042 ! cytokinesis GO:0000910 84 42 0,000 0,13863475 0,15578873 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,13863475 0,1557171 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,14169182 0,15907772 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,14169182 0,15900464 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,14169182 0,15893164 ! regulation of tube size GO:0035150 76 43 0,000 0,14169182 0,1588587 GO:0050880|regulation of blood vessel size, ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,14169182 0,15878583 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,14169182 0,15871303 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,14169182 0,15864029 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,14169182 0,15856762 ! ion transmembrane transport GO:0034220 79 43 0,000 0,14169182 0,15849501 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,14169182 0,15842248 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,14473812 0,16175445 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,14473812 0,16168049 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,14473812 0,1616066 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,14473812 0,16153277 ! striated muscle contraction GO:0006941 85 44 0,000 0,14473812 0,16145901 ! phagocytosis GO:0006909 105 44 0,000 0,14473812 0,16138532 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,14473812 0,16131169 ! double-strand break repair GO:0006302 85 44 0,000 0,14473812 0,16123814 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,1477737 0,16454473 ! regulation of epithelial cell proliferation GO:0050678 122 45 0,000 0,1477737 0,16446977 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,1477737 0,16439488 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,1477737 0,16432005 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,1477737 0,16424529 ! female gamete generation GO:0007292 71 45 0,000 0,1477737 0,1641706 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,1477737 0,16409598 ! polyol metabolic process GO:0019751 77 45 0,000 0,1477737 0,16402142 ! developmental growth GO:0048589 88 45 0,000 0,1477737 0,16394693 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,15079859 0,16722694 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,15079859 0,16715107 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 0,000 0,15079859 0,16707526 ! glycolysis GO:0006096 71 46 0,000 0,15079859 0,16699952 ! leukocyte migration GO:0050900 75 46 0,000 0,15079859 0,16692386 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,15079859 0,16684826 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,15079859 0,16677273 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,15079859 0,16669726 ! cell growth GO:0016049 90 46 0,000 0,15079859 0,16662187 ! neural tube development GO:0021915 91 47 0,000 0,15381282 0,16987556 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,15381282 0,16979879 ! positive regulation of defense response GO:0031349 88 48 0,000 0,15681645 0,1730364 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,15681645 0,17295828 ! mitochondrial transport GO:0006839 94 48 0,000 0,15681645 0,17288023 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,15681645 0,17280225 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,15681645 0,17272434 ! endosome transport GO:0016197 127 48 0,000 0,15681645 0,1726465 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,15681645 0,17256873 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,15681645 0,17249103 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,15681645 0,1724134 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,15681645 0,17233584 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,15681645 0,17225835 ! response to calcium ion GO:0051592 94 49 0,000 0,15980949 0,17546723 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,15980949 0,1753884 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,15980949 0,17530965 ! JNK cascade GO:0007254 106 49 0,000 0,15980949 0,17523096 ! regulation of mast cell proliferation GO:0070666 89 49 0,000 0,15980949 0,17515235 ! protein homooligomerization GO:0051260 84 49 0,000 0,15980949 0,17507381 ! regulation of action potential GO:0001508 102 50 0,000 0,162792 0,17826125 ! regulation of ion transport GO:0043269 86 50 0,000 0,162792 0,17818138 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,162792 0,17810159 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,162792 0,17802187 ! regulation of ossification GO:0030278 123 50 0,000 0,162792 0,17794221 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,162792 0,17786263 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,162792 0,17778312 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,165764 0,18094792 ! peptide metabolic process GO:0006518 80 51 0,000 0,165764 0,1808671 ! response to temperature stimulus GO:0009266 84 51 0,000 0,165764 0,18078636 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,16872553 0,18393417 ! Notch signaling pathway GO:0007219 111 52 0,000 0,16872553 0,18385213 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,16872553 0,18377016 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,16872553 0,18368827 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,16872553 0,18360645 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,16872553 0,1835247 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,16872553 0,18344302 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,16872553 0,18336142 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,16872553 0,18327989 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,16872553 0,18319843 ! amino acid activation GO:0043038 98 52 0,000 0,16872553 0,18311705 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,17167664 0,18623713 ! inner ear development GO:0048839 89 53 0,000 0,17167664 0,18615447 ! chromatin remodeling GO:0006338 122 53 0,000 0,17167664 0,18607188 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,17167664 0,18598937 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,17167664 0,18590692 ! vesicle organization GO:0016050 127 53 0,000 0,17167664 0,18582456 ! regulation of leukocyte proliferation GO:0070663 97 53 0,000 0,17167664 0,18574226 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,17167664 0,18566004 ! cartilage development GO:0051216 99 53 0,000 0,17167664 0,18557789 ! synapse organization GO:0050808 102 53 0,000 0,17167664 0,18549581 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,17461735 0,18858982 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,17461735 0,18850649 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,17461735 0,18842322 GO:0010863|positive regulation of phospholipase C activity, ! neuromuscular process GO:0050905 107 54 0,000 0,17461735 0,18834003 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,17461735 0,18825692 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,17461735 0,18817388 ! membrane fusion GO:0006944 122 54 0,000 0,17461735 0,18809091 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,17461735 0,18800801 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,17461735 0,18792519 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,17461735 0,18784244 ! RNA catabolic process GO:0006401 103 55 0,000 0,1775477 0,19091066 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,1775477 0,19082667 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,1775477 0,19074276 ! cell recognition GO:0008037 98 55 0,000 0,1775477 0,19065891 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,1775477 0,19057514 ! cell maturation GO:0048469 107 55 0,000 0,1775477 0,19049145 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,1775477 0,19040783 ! response to UV GO:0009411 120 55 0,000 0,1775477 0,19032428 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,1775477 0,1902408 ! skeletal muscle fiber development GO:0048741 130 56 0,000 0,18046773 0,19328482 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,18046773 0,19320012 ! glucose catabolic process GO:0006007 88 56 0,000 0,18046773 0,19311549 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,18046773 0,19303094 ! RNA elongation GO:0006354 90 56 0,000 0,18046773 0,19294646 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 0,000 0,18337748 0,19597164 ! chloride transport GO:0006821 102 57 0,000 0,18337748 0,19588595 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,18337748 0,19580034 ! muscle fiber development GO:0048747 131 57 0,000 0,18337748 0,1957148 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,18337748 0,19562933 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,18337748 0,19554394 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,18627697 0,19854915 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,18627697 0,19846256 ! gastrulation GO:0007369 122 58 0,000 0,18627697 0,19837604 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,18627697 0,19828961 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,18627697 0,19820324 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,18627697 0,19811695 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,18627697 0,19803074 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,19204536 0,2040743 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,19204536 0,20398557 ! adult behavior GO:0030534 104 60 0,000 0,19204536 0,20389692 ! kidney development GO:0001822 133 60 0,000 0,19204536 0,20380835 ! positive regulation of secretion GO:0051047 110 61 0,000 0,19491432 0,20676322 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,19491432 0,20667348 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,19491432 0,20658382 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,19491432 0,20649423 ! regulation of heart contraction GO:0008016 123 61 0,000 0,19491432 0,20640472 ! camera-type eye development GO:0043010 126 61 0,000 0,19491432 0,20631529 ! proton transport GO:0015992 117 61 0,000 0,19491432 0,20622594 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,19491432 0,20613666 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,19777318 0,20906961 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,19777318 0,20897919 ! tRNA processing GO:0008033 102 62 0,000 0,19777318 0,20888884 ! regulation of mitosis GO:0007088 112 63 0,000 0,20062197 0,21180616 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,20062197 0,21171467 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,20062197 0,21162326 ! hydrogen transport GO:0006818 121 64 0,000 0,20346071 0,21452504 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,20346071 0,21443249 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,20628946 0,21732003 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,20628946 0,21722636 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,21191709 0,22305621 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,21191709 0,22296014 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,21191709 0,22286416 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,21191709 0,22276827 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,21191709 0,22267245 ! secondary metabolic process GO:0019748 125 67 0,000 0,21191709 0,22257672 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,21471604 0,22541955 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,21471604 0,22532272 ! hexose catabolic process GO:0019320 113 68 0,000 0,21471604 0,22522597 ! extracellular matrix organization GO:0030198 146 68 0,000 0,21471604 0,22512931 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,21471604 0,22503273 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,21471604 0,22493623 ! regulation of lipase activity GO:0060191 137 68 0,000 0,21471604 0,22483982 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,21471604 0,22474349 ! negative regulation of cell size GO:0045792 144 69 0,000 0,21750513 0,22756533 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,21750513 0,22746791 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,21750513 0,22737058 ! urogenital system development GO:0001655 149 69 0,000 0,21750513 0,22727333 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,21750513 0,22717616 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 0,000 0,21750513 0,22707908 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,21750513 0,22698208 ! developmental maturation GO:0021700 128 69 0,000 0,21750513 0,22688516 ! single fertilization GO:0007338 83 69 0,000 0,21750513 0,22678832 ! germ cell development GO:0007281 133 70 0,000 0,2202844 0,22958822 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,22305387 0,23237552 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,22305387 0,23227647 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,22305387 0,2321775 ! appendage morphogenesis GO:0035107 150 72 0,000 0,22581358 0,23494999 GO:0035108|limb morphogenesis, ! B cell activation GO:0042113 179 72 0,000 0,22581358 0,23484997 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,22581358 0,23475003 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,22581358 0,23465018 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,22581358 0,23455041 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,22581358 0,23445073 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,22581358 0,23435113 ! appendage development GO:0048736 151 73 0,000 0,22856356 0,23710437 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,22856356 0,23700373 ! regulation of immune effector process GO:0002697 156 73 0,000 0,22856356 0,23690318 ! amino acid transport GO:0006865 148 74 0,000 0,23130386 0,23964178 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,23130386 0,2395402 ! transition metal ion transport GO:0000041 143 75 0,000 0,2340345 0,24226537 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,2340345 0,24216276 ! eye development GO:0001654 155 75 0,000 0,2340345 0,24206023 ! axon guidance GO:0007411 162 75 0,000 0,2340345 0,2419578 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,23675551 0,24466739 ! regulation of blood pressure GO:0008217 134 76 0,000 0,23675551 0,24456394 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,23675551 0,24446057 ! amine catabolic process GO:0009310 136 77 0,000 0,23946693 0,24715578 ! neurotransmitter transport GO:0006836 142 77 0,000 0,23946693 0,2470514 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,23946693 0,24694712 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,23946693 0,24684292 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,23946693 0,24673881 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,2421688 0,24941753 ! fertilization GO:0009566 99 78 0,000 0,2421688 0,24931243 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,2421688 0,24920741 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,24486115 0,25187191 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,24486115 0,2517659 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,24486115 0,25165999 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,247544 0,25431035 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,247544 0,25420345 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,247544 0,25409664 ! meiosis GO:0007126 143 81 0,000 0,2502174 0,25673294 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,2502174 0,25662515 ! positive regulation of phosphorylation GO:0042327 149 81 0,000 0,2502174 0,25651746 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,2502174 0,25640987 ! meiotic cell cycle GO:0051321 144 82 0,000 0,25288138 0,25903112 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,25553597 0,26164056 ! exocytosis GO:0006887 153 83 0,000 0,25553597 0,26153095 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,25553597 0,26142143 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 0,000 0,25553597 0,261312 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,25553597 0,26120266 ! inorganic anion transport GO:0015698 156 83 0,000 0,25553597 0,26109342 ! response to metal ion GO:0010038 158 84 0,000 0,2581812 0,2636859 ! response to nutrient GO:0007584 135 84 0,000 0,2581812 0,26357571 ! digestion GO:0007586 130 84 0,000 0,2581812 0,26346561 ! regulation of ligase activity GO:0051340 147 84 0,000 0,2581812 0,2633556 ! negative regulation of transport GO:0051051 164 85 0,000 0,2608171 0,2659333 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,2608171 0,26582235 ! negative regulation of growth GO:0045926 168 85 0,000 0,2608171 0,2657115 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,2608171 0,26560074 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,2608171 0,26549007 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,26344371 0,26805206 ! regulation of lyase activity GO:0051339 169 86 0,000 0,26344371 0,26794046 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,26344371 0,26782896 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,26606107 0,27037736 ! alcohol catabolic process GO:0046164 142 87 0,000 0,26606107 0,27026494 ! nucleosome assembly GO:0006334 126 87 0,000 0,26606107 0,27015261 ! cellular respiration GO:0045333 143 88 0,000 0,26866919 0,27268751 ! amine biosynthetic process GO:0009309 146 88 0,000 0,26866919 0,27257427 ! sensory perception of smell GO:0007608 117 88 0,000 0,26866919 0,27246112 ! chromatin assembly GO:0031497 128 88 0,000 0,26866919 0,27234806 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,27126812 0,27486853 ! tube morphogenesis GO:0035239 194 89 0,000 0,27126812 0,27475457 ! cellular defense response GO:0006968 123 89 0,000 0,27126812 0,27464071 ! regulation of neurological system process GO:0031644 175 89 0,000 0,27126812 0,27452694 ! response to inorganic substance GO:0010035 173 90 0,000 0,27385789 0,27703305 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,27385789 0,27691839 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,27385789 0,27680382 ! response to unfolded protein GO:0006986 139 90 0,000 0,27385789 0,27668934 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,27643853 0,2791812 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 0,000 0,27643853 0,27906584 ! defense response to bacterium GO:0042742 112 91 0,000 0,27643853 0,27895057 ! bone development GO:0060348 206 92 0,000 0,27901007 0,28142923 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,27901007 0,28131308 ! regulation of cell adhesion GO:0030155 241 92 0,000 0,27901007 0,28119703 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,28157254 0,28366256 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,28157254 0,28354563 ! vitamin metabolic process GO:0006766 153 93 0,000 0,28157254 0,2834288 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,28412597 0,28588128 ! female pregnancy GO:0007565 166 94 0,000 0,28412597 0,28576359 ! sterol metabolic process GO:0016125 166 94 0,000 0,28412597 0,28564599 ! regulation of defense response GO:0031347 171 95 0,000 0,2866704 0,28808548 ! nucleosome organization GO:0034728 143 95 0,000 0,2866704 0,28796702 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,2866704 0,28784866 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,2866704 0,2877304 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,2866704 0,28761224 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,2866704 0,28749417 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,2866704 0,2873762 ! response to protein stimulus GO:0051789 158 96 0,000 0,28920587 0,28979899 ! regulation of T cell activation GO:0050863 175 96 0,000 0,28920587 0,28968017 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,29173238 0,29209107 ! interphase of mitotic cell cycle GO:0051329 224 98 0,000 0,29424999 0,29449108 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,29424999 0,29437049 ! hormone metabolic process GO:0042445 171 100 0,000 0,29925861 0,29925861