pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/573-Desmedt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 10 5 2,000 1,592E-06 3,662E-03 ! positive regulation of pseudopodium assembly GO:0031274 13 5 2,000 1,592E-06 1,831E-03 GO:0031272|regulation of pseudopodium assembly, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 2,000 1,592E-06 1,221E-03 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 3,000 1,924E-06 1,106E-03 ! sex determination GO:0007530 29 19 3,000 3,107E-06 1,429E-03 ! positive regulation of intracellular transport GO:0032388 29 19 3,000 3,107E-06 1,191E-03 ! male sex determination GO:0030238 9 6 2,000 3,171E-06 1,042E-03 ! macrophage differentiation GO:0030225 10 6 2,000 3,171E-06 9,118E-04 ! regulation of lipid kinase activity GO:0043550 12 7 2,000 5,528E-06 1,413E-03 ! adrenal gland development GO:0030325 17 7 2,000 5,528E-06 1,271E-03 ! establishment of nucleus localization GO:0040023 13 7 2,000 5,528E-06 1,156E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 8,34E-06 1,598E-03 ! nucleus localization GO:0051647 15 9 2,000 1,316E-05 2,328E-03 ! cell junction assembly GO:0034329 56 28 3,000 1,58E-05 2,596E-03 ! regulation of cell projection assembly GO:0060491 20 10 2,000 1,873E-05 2,871E-03 ! protein sumoylation GO:0016925 12 10 2,000 1,873E-05 2,692E-03 ! filopodium assembly GO:0046847 19 11 2,000 2,565E-05 3,47E-03 ! cell junction organization GO:0034330 63 33 3,000 3,092E-05 3,951E-03 ! microspike assembly GO:0030035 23 12 2,000 3,406E-05 4,123E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 3,49E-05 4,013E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 8,144E-05 8,92E-03 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 2,000 8,532E-05 8,92E-03 ! negative regulation of translation GO:0017148 22 16 2,000 8,532E-05 8,532E-03 ! response to insulin stimulus GO:0032868 63 43 3,000 8,942E-05 8,57E-03 ! cell-substrate junction assembly GO:0007044 39 17 2,000 1,032E-04 9,494E-03 ! positive regulation of DNA replication GO:0045740 29 18 2,000 1,233E-04 0,01091092 ! nuclear export GO:0051168 69 48 3,000 1,381E-04 0,01176096 ! cellular response to reactive oxygen species GO:0034614 27 19 2,000 1,459E-04 0,01198339 ! regulation of intracellular transport GO:0032386 78 49 3,000 1,497E-04 0,01187327 ! myeloid leukocyte differentiation GO:0002573 33 21 2,000 1,986E-04 0,01522945 ! spliceosomal snRNP biogenesis GO:0000387 28 22 2,000 2,291E-04 0,01699743 ! regulation of lipid metabolic process GO:0019216 84 56 3,000 2,52E-04 0,01811336 ! interaction with host GO:0051701 37 23 2,000 2,624E-04 0,01828941 ! cellular response to oxidative stress GO:0034599 33 23 2,000 2,624E-04 0,01775149 ! response to peptide hormone stimulus GO:0043434 84 57 3,000 2,699E-04 0,01773618 ! protein maturation by protein folding GO:0022417 12 5 1,000 2,952E-04 0,0188619 ! positive regulation of glycolysis GO:0045821 11 5 1,000 2,952E-04 0,01835212 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 2,952E-04 0,01786917 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 1,000 2,952E-04 0,01741098 ! regulation of respiratory burst GO:0060263 8 5 1,000 2,952E-04 0,01697571 ! apical protein localization GO:0045176 6 5 1,000 2,952E-04 0,01656167 ! positive regulation of cell projection organization GO:0031346 39 24 2,000 2,987E-04 0,0163579 ! myeloid cell differentiation GO:0030099 85 59 3,000 3,084E-04 0,01649469 ! male gonad development GO:0008584 33 25 2,000 3,381E-04 0,01767312 ! cell-matrix adhesion GO:0007160 114 61 3,000 3,506E-04 0,01792175 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 4,413E-04 0,02206294 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 4,413E-04 0,02159352 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 1,000 4,413E-04 0,02114366 GO:0031958|corticosteroid receptor signaling pathway, ! ER overload response GO:0006983 7 6 1,000 4,413E-04 0,02071215 ! maintenance of protein location in nucleus GO:0051457 16 6 1,000 4,413E-04 0,02029791 ! interaction with symbiont GO:0051702 8 6 1,000 4,413E-04 0,01989991 ! regulation of meiosis GO:0040020 10 6 1,000 4,413E-04 0,01951722 GO:0051445|regulation of meiotic cell cycle, ! regulation of T cell receptor signaling pathway GO:0050856 8 6 1,000 4,413E-04 0,01914897 ! cell-substrate adhesion GO:0031589 121 66 3,000 4,742E-04 0,02019878 ! negative regulation of protein complex assembly GO:0031333 42 28 2,000 4,759E-04 0,01989925 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 6,156E-04 0,02528157 ! asymmetric protein localization GO:0008105 8 7 1,000 6,156E-04 0,02483804 ! protein heterooligomerization GO:0051291 10 7 1,000 6,156E-04 0,02440979 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 1,000 6,156E-04 0,02399607 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 2,000 7,091E-04 0,02718199 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 7,322E-04 0,02760739 ! RNA export from nucleus GO:0006405 44 33 2,000 7,769E-04 0,02882096 ! positive regulation of DNA metabolic process GO:0051054 54 33 2,000 7,769E-04 0,02836348 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 8,178E-04 0,02938964 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 8,178E-04 0,02893749 ! middle ear morphogenesis GO:0042474 9 8 1,000 8,178E-04 0,02849905 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 8,178E-04 0,02807369 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 8,178E-04 0,02766084 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 8,178E-04 0,02725996 ! regulation of telomere maintenance GO:0032204 10 8 1,000 8,178E-04 0,02687053 ! regulation of embryonic development GO:0045995 16 8 1,000 8,178E-04 0,02649207 ! establishment or maintenance of cell polarity GO:0007163 61 34 2,000 8,487E-04 0,02711191 ! development of primary male sexual characteristics GO:0046546 44 34 2,000 8,487E-04 0,02674051 ! protein localization in nucleus GO:0034504 133 80 3,000 9,815E-04 0,03050653 ! positive regulation of transcription factor activity GO:0051091 49 36 2,000 1,005E-03 0,03080986 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 2,000 1,005E-03 0,03040446 ! regulation of developmental growth GO:0048638 13 9 1,000 1,048E-03 0,03129479 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 1,048E-03 0,03089358 ! regulation of glycolysis GO:0006110 15 9 1,000 1,048E-03 0,03050252 ! positive regulation of phagocytosis GO:0050766 11 9 1,000 1,048E-03 0,03012124 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 1,048E-03 0,02974937 ! sequestering of metal ion GO:0051238 11 9 1,000 1,048E-03 0,02938657 ! pigmentation GO:0043473 74 38 2,000 1,178E-03 0,03263357 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 1,231E-03 0,03369514 ! male sex differentiation GO:0046661 53 39 2,000 1,271E-03 0,03438453 ! cortical actin cytoskeleton organization GO:0030866 19 10 1,000 1,305E-03 0,03489949 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,305E-03 0,03449835 ! DNA methylation GO:0006306 15 10 1,000 1,305E-03 0,03410632 GO:0006305|DNA alkylation, ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 1,305E-03 0,0337231 GO:0043470|regulation of carbohydrate catabolic process, ! T cell receptor signaling pathway GO:0050852 18 10 1,000 1,305E-03 0,0333484 ! reproductive developmental process GO:0003006 127 89 3,000 1,459E-03 0,03688566 ! positive regulation of DNA binding GO:0043388 57 41 2,000 1,471E-03 0,03676279 ! regulation of cell shape GO:0008360 78 42 2,000 1,577E-03 0,03901005 ! cortical cytoskeleton organization GO:0030865 20 11 1,000 1,589E-03 0,03888528 ! virus-host interaction GO:0019048 17 11 1,000 1,589E-03 0,03847596 ! detection of mechanical stimulus GO:0050982 15 11 1,000 1,589E-03 0,03807517 ! focal adhesion formation GO:0048041 24 11 1,000 1,589E-03 0,03768264 ! regulation of phagocytosis GO:0050764 14 11 1,000 1,589E-03 0,03729812 ! actin filament polymerization GO:0030041 17 11 1,000 1,589E-03 0,03692137 ! regulation of steroid biosynthetic process GO:0050810 11 11 1,000 1,589E-03 0,03655216 ! positive regulation of binding GO:0051099 59 43 2,000 1,689E-03 0,03846143 ! activation of caspase activity GO:0006919 65 43 2,000 1,689E-03 0,03808436 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,716E-03 0,03832503 ! regulation of cell projection organization GO:0031344 83 44 2,000 1,805E-03 0,03992653 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 1,9E-03 0,04162469 ! cell-cell junction assembly GO:0007043 18 12 1,000 1,9E-03 0,041232 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 1,9E-03 0,04084665 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 1,9E-03 0,04046844 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,9E-03 0,04009717 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 1,927E-03 0,04028516 ! protein maturation GO:0051604 129 96 3,000 1,928E-03 0,03995931 ! calcium ion transport GO:0006816 167 99 3,000 2,158E-03 0,04431942 ! endocrine system development GO:0035270 83 47 2,000 2,184E-03 0,04445847 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 2,238E-03 0,0451474 ! cellular pigmentation GO:0033059 24 13 1,000 2,238E-03 0,04475481 ! regulation of translation GO:0006417 151 100 3,000 2,239E-03 0,04438889 ! divalent metal ion transport GO:0070838 171 100 3,000 2,239E-03 0,0440095 ! protein localization in organelle GO:0033365 161 100 3,000 2,239E-03 0,04363654 ! positive regulation of caspase activity GO:0043280 72 48 2,000 2,321E-03 0,04485343 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 2,000 2,321E-03 0,04447965 ! integrin-mediated signaling pathway GO:0007229 81 49 2,000 2,462E-03 0,04680334 ! maintenance of location GO:0051235 84 49 2,000 2,462E-03 0,0464197 ! regulation of lipid biosynthetic process GO:0046890 16 14 1,000 2,601E-03 0,04864369 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,601E-03 0,0482514 ! limbic system development GO:0021761 25 14 1,000 2,601E-03 0,04786539 ! pituitary gland development GO:0021983 23 14 1,000 2,601E-03 0,0474855 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 2,601E-03 0,0471116 ! cell killing GO:0001906 20 14 1,000 2,601E-03 0,04674354 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,601E-03 0,04638119 ! aging GO:0007568 79 52 2,000 2,919E-03 0,0516385 ! establishment of organelle localization GO:0051656 85 52 2,000 2,919E-03 0,05124431 ! lipid phosphorylation GO:0046834 23 15 1,000 2,991E-03 0,05211389 ! regulation of survival gene product expression GO:0045884 20 15 1,000 2,991E-03 0,05172206 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 2,991E-03 0,05133607 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 2,991E-03 0,0509558 ! cell projection assembly GO:0030031 76 53 2,000 3,082E-03 0,0521155 ! regulation of protein complex assembly GO:0043254 81 54 2,000 3,25E-03 0,05456224 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 3,406E-03 0,05676607 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,406E-03 0,05635768 ! cellular response to hydrogen peroxide GO:0070301 21 16 1,000 3,406E-03 0,05595513 GO:0042744|hydrogen peroxide catabolic process, ! complement activation, alternative pathway GO:0006957 16 16 1,000 3,406E-03 0,05555828 ! protein export from nucleus GO:0006611 24 16 1,000 3,406E-03 0,05516703 ! regulation of steroid metabolic process GO:0019218 21 16 1,000 3,406E-03 0,05478124 ! diencephalon development GO:0021536 25 16 1,000 3,406E-03 0,05440082 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 3,406E-03 0,05402564 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 1,000 3,406E-03 0,0536556 ! gonad development GO:0008406 79 57 2,000 3,789E-03 0,05927896 ! memory GO:0007613 25 17 1,000 3,846E-03 0,0597741 ! keratinization GO:0031424 17 17 1,000 3,846E-03 0,05937293 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 3,846E-03 0,05897711 ! actin polymerization or depolymerization GO:0008154 31 17 1,000 3,846E-03 0,05858654 ! actin filament bundle formation GO:0051017 26 17 1,000 3,846E-03 0,0582011 ! peptidyl-serine modification GO:0018209 27 17 1,000 3,846E-03 0,0578207 ! cell-cell junction organization GO:0045216 25 17 1,000 3,846E-03 0,05744524 ! negative regulation of kinase activity GO:0033673 100 58 2,000 3,98E-03 0,05905226 ! actin filament organization GO:0007015 95 59 2,000 4,176E-03 0,06157339 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 4,312E-03 0,06316514 ! peptide cross-linking GO:0018149 31 18 1,000 4,312E-03 0,06276536 ! somitogenesis GO:0001756 24 18 1,000 4,312E-03 0,06237061 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 4,312E-03 0,0619808 ! regulation of homeostatic process GO:0032844 105 60 2,000 4,379E-03 0,06255385 ! negative regulation of transferase activity GO:0051348 105 61 2,000 4,587E-03 0,06512579 ! organelle localization GO:0051640 96 62 2,000 4,801E-03 0,0677496 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 4,802E-03 0,06734238 GO:0010675|regulation of cellular carbohydrate metabolic process, ! calcium-independent cell-cell adhesion GO:0016338 21 19 1,000 4,802E-03 0,06693424 ! response to alkaloid GO:0043279 32 19 1,000 4,802E-03 0,06653102 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 4,802E-03 0,06613264 ! apoptotic nuclear changes GO:0030262 24 19 1,000 4,802E-03 0,06573899 ! response to lipopolysaccharide GO:0032496 26 19 1,000 4,802E-03 0,06535 ! cytolysis GO:0019835 20 19 1,000 4,802E-03 0,06496559 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 4,802E-03 0,06458567 ! protein stabilization GO:0050821 26 19 1,000 4,802E-03 0,06421018 ! regulation of transcription factor activity GO:0051090 97 63 2,000 5,022E-03 0,06676128 GO:0090046|regulation of transcription regulator activity, ! microtubule-based transport GO:0010970 37 20 1,000 5,316E-03 0,07027351 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 5,316E-03 0,06987195 ! DNA modification GO:0006304 28 20 1,000 5,316E-03 0,06947495 ! reproductive structure development GO:0048608 90 65 2,000 5,48E-03 0,07121061 ! regulation of caspase activity GO:0043281 97 65 2,000 5,48E-03 0,07081055 ! activation of immune response GO:0002253 83 65 2,000 5,48E-03 0,07041496 ! gluconeogenesis GO:0006094 25 21 1,000 5,855E-03 0,07481452 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 5,855E-03 0,07440118 ! protein amino acid acylation GO:0043543 37 21 1,000 5,855E-03 0,07399238 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 5,855E-03 0,07358805 ! cell aging GO:0007569 32 21 1,000 5,855E-03 0,07318812 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 5,855E-03 0,07279251 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 5,963E-03 0,07373613 ! acute inflammatory response GO:0002526 92 68 2,000 6,214E-03 0,07642517 ! learning or memory GO:0007611 123 68 2,000 6,214E-03 0,07601865 ! development of primary sexual characteristics GO:0045137 92 68 2,000 6,214E-03 0,07561643 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 1,000 6,418E-03 0,07768728 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! protein tetramerization GO:0051262 39 22 1,000 6,418E-03 0,07728054 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 7,004E-03 0,08390037 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 7,004E-03 0,08346566 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 7,004E-03 0,08303542 ! hydrogen peroxide metabolic process GO:0042743 30 23 1,000 7,004E-03 0,0826096 ! response to molecule of bacterial origin GO:0002237 30 23 1,000 7,004E-03 0,08218812 ! regulation of peptidase activity GO:0052547 106 72 2,000 7,279E-03 0,08498336 ! mitochondrion organization GO:0007005 104 73 2,000 7,561E-03 0,08783164 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 7,613E-03 0,08799426 ! pyruvate metabolic process GO:0006090 29 24 1,000 7,613E-03 0,08755428 ! protein import into nucleus GO:0006606 118 74 2,000 7,85E-03 0,08982251 ! blood coagulation GO:0007596 116 75 2,000 8,145E-03 0,09273652 GO:0050817|coagulation, ! nuclear import GO:0051170 121 75 2,000 8,145E-03 0,09227968 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 1,000 8,246E-03 0,0929702 ! iron ion homeostasis GO:0055072 39 25 1,000 8,246E-03 0,09251669 ! regulation of chromosome organization GO:0033044 35 25 1,000 8,246E-03 0,09206758 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 8,246E-03 0,09162281 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 8,446E-03 0,09339467 ! regulation of DNA binding GO:0051101 119 77 2,000 8,754E-03 0,09633655 ! gland development GO:0048732 148 77 2,000 8,754E-03 0,0958778 ! sex differentiation GO:0007548 105 77 2,000 8,754E-03 0,09542341 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 8,902E-03 0,09657289 ! acute-phase response GO:0006953 42 27 1,000 9,579E-03 0,10344057 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 1,000 9,579E-03 0,1029572 ! hemostasis GO:0007599 125 81 2,000 0,0100513 0,1075255 ! mRNA transport GO:0051028 121 81 2,000 0,0100513 0,1070277 ! positive regulation of endocytosis GO:0045807 33 28 1,000 0,01027978 0,10895616 ! complement activation, classical pathway GO:0006958 36 28 1,000 0,01027978 0,10845636 ! immune response-activating signal transduction GO:0002757 38 28 1,000 0,01027978 0,10796112 GO:0002764|immune response-regulating signal transduction, ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,01027978 0,10747039 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,01100208 0,11450131 ! ovulation cycle process GO:0022602 41 29 1,000 0,01100208 0,11398553 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,01100208 0,11347439 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 1,000 0,01174615 0,12060784 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 1,000 0,01174615 0,12007181 ! ovulation cycle GO:0042698 43 30 1,000 0,01174615 0,11954051 ! cell cycle arrest GO:0007050 150 86 2,000 0,01182215 0,11978386 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,01251174 0,12621492 ! segmentation GO:0035282 41 31 1,000 0,01251174 0,12566376 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,01251174 0,1251174 ! establishment of RNA localization GO:0051236 128 88 2,000 0,01257752 0,12523068 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 2,000 0,01257752 0,12469089 ! regulation of protein stability GO:0031647 48 32 1,000 0,01329858 0,13127356 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,01329858 0,13071256 ! leukocyte differentiation GO:0002521 143 90 2,000 0,01335999 0,13075738 ! protein modification by small protein conjugation GO:0032446 140 90 2,000 0,01335999 0,13020333 ! RNA localization GO:0006403 135 91 2,000 0,01376144 0,13354985 ! ear morphogenesis GO:0042471 42 33 1,000 0,01410643 0,13632266 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 1,000 0,01410643 0,13575228 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,01410643 0,13518664 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 0,01410643 0,1346257 ! female gonad development GO:0008585 49 33 1,000 0,01410643 0,1340694 ! positive regulation of immune response GO:0050778 121 92 2,000 0,01416971 0,13411663 ! feeding behavior GO:0007631 45 34 1,000 0,01493504 0,14078111 ! neuron migration GO:0001764 46 34 1,000 0,01493504 0,14020649 ! response to oxidative stress GO:0006979 141 94 2,000 0,0150068 0,14030744 ! regulation of binding GO:0051098 151 95 2,000 0,01543563 0,1437326 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,01578416 0,14638532 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,01578416 0,14579743 ! maintenance of protein location GO:0045185 65 35 1,000 0,01578416 0,14521424 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01578416 0,14463569 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 2,000 0,01587135 0,14485753 ! regulation of cellular component biogenesis GO:0044087 158 96 2,000 0,01587135 0,14428497 ! protein modification by small protein conjugation or removal GO:0070647 148 96 2,000 0,01587135 0,14371692 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 0,01631395 0,14714545 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,01665354 0,14962163 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 49 36 1,000 0,01665354 0,14903944 GO:0006073|cellular glucan metabolic process, ! protein import GO:0017038 156 99 2,000 0,01721987 0,15351049 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,01721987 0,15291779 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 1,000 0,01754294 0,15518755 GO:0006956|complement activation, ! learning GO:0007612 67 37 1,000 0,01754294 0,15459296 ! regulation of body fluid levels GO:0050878 154 100 2,000 0,01768321 0,15523426 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,01845212 0,16136838 ! maintenance of location in cell GO:0051651 69 38 1,000 0,01845212 0,16075714 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,02032887 0,17643929 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 0,02032887 0,17577599 ! induction of apoptosis by intracellular signals GO:0008629 67 40 1,000 0,02032887 0,17511765 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,02032887 0,17446423 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,02032887 0,17381566 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,02032887 0,1731719 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,02129597 0,18074071 ! glucose transport GO:0015758 52 41 1,000 0,02129597 0,18007622 ! biopolymer methylation GO:0043414 62 41 1,000 0,02129597 0,1794166 ! receptor-mediated endocytosis GO:0006898 76 42 1,000 0,0222819 0,18703785 ! cellular component disassembly GO:0022411 64 42 1,000 0,0222819 0,18635772 ! hexose transport GO:0008645 54 42 1,000 0,0222819 0,18568251 GO:0015749|monosaccharide transport, ! excretion GO:0007588 63 42 1,000 0,0222819 0,18501217 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,0222819 0,18434666 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,02328643 0,19196702 ! methylation GO:0032259 64 43 1,000 0,02328643 0,19128143 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,02430934 0,19897326 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,0253504 0,20675855 ! regulation of translational initiation GO:0006446 64 45 1,000 0,0253504 0,20602796 ! cell redox homeostasis GO:0045454 63 46 1,000 0,02640937 0,21387871 ! histone modification GO:0016570 68 46 1,000 0,02640937 0,21312826 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02715999 0,21841947 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02715999 0,21765843 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02715999 0,21690267 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02715999 0,21615214 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02715999 0,21540679 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02715999 0,21466656 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02715999 0,2139314 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02715999 0,21320126 ! sleep GO:0030431 11 5 0,000 0,02715999 0,21247609 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02715999 0,21175583 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02715999 0,21104044 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02715999 0,21032986 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02715999 0,20962406 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02715999 0,20892297 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02715999 0,20822656 ! tongue development GO:0043586 6 5 0,000 0,02715999 0,20753478 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02715999 0,20684758 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02715999 0,20616492 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02715999 0,20548674 ! cobalt ion transport GO:0006824 9 5 0,000 0,02715999 0,20481301 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02715999 0,20414369 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02715999 0,20347873 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02715999 0,20281808 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02715999 0,20216171 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02715999 0,20150958 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02715999 0,20086164 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02715999 0,20021785 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02715999 0,19957818 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02715999 0,19894258 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02715999 0,19831101 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02715999 0,19768345 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02715999 0,19705984 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02715999 0,19644016 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02715999 0,19582436 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02715999 0,1952124 ! malate metabolic process GO:0006108 7 5 0,000 0,02715999 0,19460427 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02715999 0,19399991 ! behavioral response to pain GO:0048266 7 5 0,000 0,02715999 0,19339929 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02715999 0,19280237 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02715999 0,19220914 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02715999 0,19161954 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02715999 0,19103355 ! mating behavior GO:0007617 6 5 0,000 0,02715999 0,19045113 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02715999 0,18987225 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02715999 0,18929688 ! rhythmic behavior GO:0007622 12 5 0,000 0,02715999 0,18872498 ! copulation GO:0007620 7 5 0,000 0,02715999 0,18815653 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02715999 0,1875915 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02715999 0,18702985 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02715999 0,18647155 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02715999 0,18591658 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02715999 0,18536489 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02715999 0,18481648 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02715999 0,1842713 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02715999 0,18372932 ! response to protozoan GO:0001562 9 5 0,000 0,02715999 0,18319053 ! lymph vessel development GO:0001945 7 5 0,000 0,02715999 0,18265488 ! endochondral ossification GO:0001958 12 5 0,000 0,02715999 0,18212236 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02715999 0,18159293 ! parathyroid gland development GO:0060017 8 5 0,000 0,02715999 0,18106658 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02715999 0,18054326 ! anagen GO:0042640 6 5 0,000 0,02715999 0,18002297 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02715999 0,17950566 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02715999 0,17899132 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02715999 0,17847991 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02715999 0,17797142 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02715999 0,17746582 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02715999 0,17696309 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02715999 0,17646319 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02715999 0,17596611 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02715999 0,17547182 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02715999 0,17498031 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02715999 0,17449153 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02715999 0,17400549 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02715999 0,17352214 ! ovulation GO:0030728 6 5 0,000 0,02715999 0,17304147 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02715999 0,17256345 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02715999 0,17208807 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02715999 0,1716153 ! response to pH GO:0009268 9 5 0,000 0,02715999 0,17114512 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02715999 0,17067751 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02715999 0,17021245 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02715999 0,16974992 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02715999 0,16928989 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02715999 0,16883235 ! polyol catabolic process GO:0046174 7 5 0,000 0,02715999 0,16837728 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02715999 0,16792465 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02715999 0,16747445 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02715999 0,16702666 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02715999 0,16658125 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02715999 0,16613822 ! urea metabolic process GO:0019627 6 5 0,000 0,02715999 0,16569753 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02715999 0,16525918 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02715999 0,16482314 ! neutrophil activation GO:0042119 5 5 0,000 0,02715999 0,16438939 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02715999 0,16395793 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02715999 0,16352872 ! response to food GO:0032094 5 5 0,000 0,02715999 0,16310175 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02715999 0,162677 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02715999 0,16225447 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02715999 0,16183412 ! forebrain neuron development GO:0021884 7 5 0,000 0,02715999 0,16141594 ! melanosome organization GO:0032438 7 5 0,000 0,02715999 0,16099992 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02715999 0,16058604 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02715999 0,16017428 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02715999 0,15976463 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02715999 0,15935706 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02715999 0,15895158 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02715999 0,15854815 ! nucleoside transport GO:0015858 6 5 0,000 0,02715999 0,15814676 ! nucleoside salvage GO:0043174 7 5 0,000 0,02715999 0,1577474 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02715999 0,15735005 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02715999 0,1569547 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02715999 0,15656133 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02715999 0,15616992 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02715999 0,15578047 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02715999 0,15539296 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02715999 0,15500737 ! depyrimidination GO:0045008 8 5 0,000 0,02715999 0,15462369 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02715999 0,1542419 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02715999 0,15386199 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02715999 0,15348395 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02715999 0,15310777 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02715999 0,15273342 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02715999 0,1523609 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02715999 0,15199019 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02715999 0,15162129 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02715999 0,15125416 ! monocyte differentiation GO:0030224 8 5 0,000 0,02715999 0,15088882 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02715999 0,15052523 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02715999 0,15016339 ! centrosome duplication GO:0051298 5 5 0,000 0,02715999 0,14980328 ! response to UV-C GO:0010225 6 5 0,000 0,02715999 0,1494449 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02715999 0,14908823 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02715999 0,14873326 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02715999 0,14837997 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02715999 0,14802836 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02715999 0,14767841 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02715999 0,14733012 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02715999 0,14698346 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02715999 0,14663843 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02715999 0,14629501 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02715999 0,1459532 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02715999 0,14561298 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02715999 0,14527435 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02715999 0,14493728 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02715999 0,14460178 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02715999 0,14426783 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02715999 0,14393541 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02715999 0,14360453 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02715999 0,14327516 ! neural tube patterning GO:0021532 6 5 0,000 0,02715999 0,1429473 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02715999 0,14262093 ! histone demethylation GO:0016577 9 5 0,000 0,02715999 0,14229606 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02715999 0,14197266 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02715999 0,14165072 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02715999 0,14133025 ! enteric nervous system development GO:0048484 8 5 0,000 0,02715999 0,14101122 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02715999 0,14069362 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02715999 0,14037746 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02715999 0,14006271 ! transcription termination GO:0006353 8 5 0,000 0,02715999 0,13974937 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02715999 0,13943743 ! plasminogen activation GO:0031639 5 5 0,000 0,02715999 0,13912688 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02715999 0,13881771 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02715999 0,13850991 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02715999 0,13820347 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02715999 0,13789839 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02715999 0,13759465 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02715999 0,13729224 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02715999 0,13699116 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02715999 0,1366914 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02715999 0,13639295 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02715999 0,13609579 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02715999 0,13579993 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02715999 0,13550536 ! glial cell migration GO:0008347 10 5 0,000 0,02715999 0,13521206 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02715999 0,13492002 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02715999 0,13462924 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02715999 0,13433972 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02715999 0,13405144 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02715999 0,13376439 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02715999 0,13347857 ! neural plate development GO:0001840 6 5 0,000 0,02715999 0,13319396 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,02715999 0,13291057 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02715999 0,13262839 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02715999 0,13234739 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02715999 0,13206759 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02715999 0,13178897 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02715999 0,13151151 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02715999 0,13123523 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02715999 0,1309601 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02715999 0,13068613 ! spindle assembly GO:0051225 5 5 0,000 0,02715999 0,1304133 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02715999 0,1301416 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02715999 0,12987104 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02715999 0,1296016 ! organ regeneration GO:0031100 7 5 0,000 0,02715999 0,12933327 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02715999 0,12906605 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02715999 0,12879994 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02715999 0,12853492 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02715999 0,12827098 GO:0055081|anion homeostasis, ! covalent chromatin modification GO:0016569 75 47 1,000 0,02748604 0,12954487 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,02748604 0,12927995 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,02858019 0,13415191 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,02858019 0,13387868 ! heart morphogenesis GO:0003007 65 48 1,000 0,02858019 0,13360657 ! immunoglobulin mediated immune response GO:0016064 66 48 1,000 0,02858019 0,13333557 GO:0019724|B cell mediated immunity, ! regulation of endocytosis GO:0030100 63 48 1,000 0,02858019 0,13306566 ! regulation of actin filament length GO:0030832 72 50 1,000 0,03082003 0,14320417 ! ear development GO:0043583 72 50 1,000 0,03082003 0,14291545 ! lipid modification GO:0030258 73 50 1,000 0,03082003 0,14262789 ! positive regulation of growth GO:0045927 67 50 1,000 0,03082003 0,14234149 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,03196529 0,14733498 ! tRNA transcription GO:0009304 11 6 0,000 0,03250373 0,14951717 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03250373 0,14921873 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03250373 0,14892148 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03250373 0,14862542 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03250373 0,14833052 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03250373 0,1480368 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03250373 0,14774424 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03250373 0,14745283 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03250373 0,14716257 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03250373 0,14687345 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03250373 0,14658546 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03250373 0,1462986 ! prostate gland development GO:0030850 9 6 0,000 0,03250373 0,14601286 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03250373 0,14572823 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03250373 0,14544472 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03250373 0,1451623 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03250373 0,14488098 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03250373 0,14460074 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03250373 0,14432159 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03250373 0,14404351 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03250373 0,14376651 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03250373 0,14349056 ! neuron adhesion GO:0007158 9 6 0,000 0,03250373 0,14321568 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03250373 0,14294184 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03250373 0,14266905 ! signal peptide processing GO:0006465 8 6 0,000 0,03250373 0,1423973 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03250373 0,14212659 ! mRNA stabilization GO:0048255 15 6 0,000 0,03250373 0,1418569 GO:0043489|RNA stabilization, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03250373 0,14158823 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03250373 0,14132058 ! opsonization GO:0008228 8 6 0,000 0,03250373 0,14105393 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03250373 0,14078829 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03250373 0,14052365 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03250373 0,14026001 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03250373 0,13999735 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03250373 0,13973567 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03250373 0,13947497 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03250373 0,13921524 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03250373 0,13895648 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03250373 0,13869867 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03250373 0,13844182 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03250373 0,13818592 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03250373 0,13793097 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03250373 0,13767695 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03250373 0,13742387 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03250373 0,13717171 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03250373 0,13692048 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03250373 0,13667017 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03250373 0,13642077 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03250373 0,13617228 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03250373 0,1359247 ! thymic T cell selection GO:0045061 12 6 0,000 0,03250373 0,13567801 ! protein lipoylation GO:0009249 10 6 0,000 0,03250373 0,13543222 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03250373 0,13518731 ! pigment granule organization GO:0048753 11 6 0,000 0,03250373 0,13494329 ! drug transport GO:0015893 6 6 0,000 0,03250373 0,13470015 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03250373 0,13445789 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03250373 0,13421649 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03250373 0,13397596 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03250373 0,13373629 ! histidine metabolic process GO:0006547 6 6 0,000 0,03250373 0,13349747 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03250373 0,13325951 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03250373 0,13302239 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03250373 0,13278612 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03250373 0,13255068 ! adenohypophysis development GO:0021984 10 6 0,000 0,03250373 0,13231608 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03250373 0,1320823 ! hyperosmotic response GO:0006972 8 6 0,000 0,03250373 0,13184935 ! microtubule nucleation GO:0007020 10 6 0,000 0,03250373 0,13161723 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03250373 0,13138591 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03250373 0,13115541 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03250373 0,13092572 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03250373 0,13069683 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03250373 0,13046873 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03250373 0,13024144 ! response to dietary excess GO:0002021 7 6 0,000 0,03250373 0,13001493 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03250373 0,12978921 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03250373 0,12956427 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03250373 0,12934011 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03250373 0,12911673 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03250373 0,12889411 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03250373 0,12867226 ! neuron apoptosis GO:0051402 8 6 0,000 0,03250373 0,12845118 ! organic alcohol transport GO:0015850 9 6 0,000 0,03250373 0,12823085 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03250373 0,12801127 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03250373 0,12779245 ! carnitine transport GO:0015879 8 6 0,000 0,03250373 0,12757438 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03250373 0,12735704 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03250373 0,12714045 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03250373 0,12692459 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03250373 0,12670946 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03250373 0,12649507 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03250373 0,12628139 ! parturition GO:0007567 12 6 0,000 0,03250373 0,12606844 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03250373 0,1258562 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03250373 0,12564468 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03250373 0,12543387 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03250373 0,12522376 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03250373 0,12501435 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03250373 0,12480565 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03250373 0,12459764 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03250373 0,12439032 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03250373 0,12418369 ! astrocyte development GO:0014002 14 6 0,000 0,03250373 0,12397775 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03250373 0,12377249 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03250373 0,12356791 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03250373 0,123364 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03250373 0,12316076 ! eating behavior GO:0042755 6 6 0,000 0,03250373 0,1229582 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03250373 0,1227563 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03250373 0,12255506 ! response to copper ion GO:0046688 9 6 0,000 0,03250373 0,12235448 ! DNA topological change GO:0006265 8 6 0,000 0,03250373 0,12215455 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03250373 0,12195528 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03250373 0,12175665 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03250373 0,12155867 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03250373 0,12136134 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03250373 0,12116464 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03250373 0,12096858 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03250373 0,12077316 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03250373 0,12057836 ! gas homeostasis GO:0033483 11 6 0,000 0,03250373 0,12038419 ! hair follicle maturation GO:0048820 7 6 0,000 0,03250373 0,12019065 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03250373 0,11999773 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03250373 0,11980542 ! Schwann cell development GO:0014044 14 6 0,000 0,03250373 0,11961373 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03250373 0,11942266 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03250373 0,11923219 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03250373 0,11904233 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03250373 0,11885308 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03250373 0,11866442 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03250373 0,11847636 ! histone ubiquitination GO:0016574 7 6 0,000 0,03250373 0,1182889 ! G2 phase GO:0051319 13 6 0,000 0,03250373 0,11810203 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03250373 0,11791575 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03250373 0,11773005 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03250373 0,11754494 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03250373 0,11736041 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03250373 0,11717646 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03250373 0,11699309 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03250373 0,11681029 ! receptor internalization GO:0031623 9 6 0,000 0,03250373 0,11662806 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03250373 0,11644639 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03250373 0,11626529 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03250373 0,11608476 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03250373 0,11590478 ! protein deubiquitination GO:0016579 8 6 0,000 0,03250373 0,11572536 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03250373 0,1155465 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03250373 0,11536819 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03250373 0,11519042 ! axonal fasciculation GO:0007413 9 6 0,000 0,03250373 0,11501321 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03250373 0,11483653 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03250373 0,11466041 ! midbrain development GO:0030901 6 6 0,000 0,03250373 0,11448482 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03250373 0,11430976 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03250373 0,11413524 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,03250373 0,11396126 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03250373 0,1137878 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03250373 0,11361487 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03250373 0,11344246 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03250373 0,11327058 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03250373 0,11309922 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03250373 0,11292838 ! adult feeding behavior GO:0008343 6 6 0,000 0,03250373 0,11275805 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03250373 0,11258823 ! blastocyst growth GO:0001832 15 6 0,000 0,03250373 0,11241892 ! pigment granule transport GO:0051904 12 6 0,000 0,03250373 0,11225013 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03250373 0,11208184 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03250373 0,11191405 ! catecholamine transport GO:0051937 7 6 0,000 0,03250373 0,11174676 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03250373 0,11157998 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03250373 0,11141369 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03250373 0,11124789 ! protein prenylation GO:0018342 10 6 0,000 0,03250373 0,11108259 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03250373 0,11091778 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,03250373 0,11075346 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03250373 0,11058962 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03250373 0,11042627 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03250373 0,1102634 ! regulation of cellular component size GO:0032535 74 52 1,000 0,03312715 0,11221273 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03430541 0,11603299 ! DNA catabolic process GO:0006308 67 54 1,000 0,03549984 0,11989668 ! detection of external stimulus GO:0009581 66 54 1,000 0,03549984 0,11972088 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,03781843 0,12735342 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03781843 0,12716723 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03781843 0,12698159 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03781843 0,12679648 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03781843 0,12661192 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03781843 0,12642789 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03781843 0,12624439 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03781843 0,12606143 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03781843 0,125879 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03781843 0,12569709 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03781843 0,12551571 ! reproductive behavior GO:0019098 12 7 0,000 0,03781843 0,12533485 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03781843 0,12515451 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03781843 0,12497469 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03781843 0,12479539 ! oligopeptide transport GO:0006857 11 7 0,000 0,03781843 0,1246166 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03781843 0,12443832 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03781843 0,12426055 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03781843 0,12408329 ! RNA methylation GO:0001510 11 7 0,000 0,03781843 0,12390653 ! pericardium development GO:0060039 8 7 0,000 0,03781843 0,12373028 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03781843 0,12355453 ! fibril organization GO:0043206 13 7 0,000 0,03781843 0,12337927 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03781843 0,12320451 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03781843 0,12303025 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03781843 0,12285648 ! lipoprotein transport GO:0042953 9 7 0,000 0,03781843 0,1226832 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03781843 0,1225104 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03781843 0,1223381 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03781843 0,12216627 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03781843 0,12199493 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03781843 0,12182407 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03781843 0,12165369 ! chemosensory behavior GO:0007635 9 7 0,000 0,03781843 0,12148378 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03781843 0,12131435 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,03781843 0,12114539 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03781843 0,12097689 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03781843 0,12080887 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03781843 0,12064131 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03781843 0,12047422 ! reflex GO:0060004 12 7 0,000 0,03781843 0,12030759 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03781843 0,12014142 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03781843 0,11997571 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03781843 0,11981045 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03781843 0,11964565 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03781843 0,1194813 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03781843 0,1193174 ! spinal cord patterning GO:0021511 7 7 0,000 0,03781843 0,11915395 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03781843 0,11899095 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03781843 0,1188284 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03781843 0,11866629 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03781843 0,11850461 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03781843 0,11834338 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03781843 0,11818259 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03781843 0,11802223 ! endosome organization GO:0007032 10 7 0,000 0,03781843 0,11786231 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03781843 0,11770282 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03781843 0,11754377 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03781843 0,11738514 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03781843 0,11722694 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03781843 0,11706916 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03781843 0,11691181 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03781843 0,11675488 ! galactose metabolic process GO:0006012 10 7 0,000 0,03781843 0,11659837 ! vesicle fusion GO:0006906 15 7 0,000 0,03781843 0,11644229 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03781843 0,11628661 GO:0045851|pH reduction, ! organ growth GO:0035265 11 7 0,000 0,03781843 0,11613136 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03781843 0,11597652 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03781843 0,11582209 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03781843 0,11566807 ! retinol metabolic process GO:0042572 9 7 0,000 0,03781843 0,11551446 ! behavioral fear response GO:0001662 13 7 0,000 0,03781843 0,11536126 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03781843 0,11520846 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03781843 0,11505607 ! rRNA modification GO:0000154 12 7 0,000 0,03781843 0,11490408 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03781843 0,11475249 ! response to UV-B GO:0010224 11 7 0,000 0,03781843 0,1146013 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,03781843 0,11445051 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03781843 0,11430011 ! intermediate filament organization GO:0045109 11 7 0,000 0,03781843 0,11415011 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03781843 0,11400051 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03781843 0,11385129 ! fibrinolysis GO:0042730 9 7 0,000 0,03781843 0,11370247 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03781843 0,11355403 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03781843 0,11340598 ! B cell lineage commitment GO:0002326 17 7 0,000 0,03781843 0,11325832 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03781843 0,11311104 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03781843 0,11296414 ! response to tropane GO:0014073 13 7 0,000 0,03781843 0,11281762 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03781843 0,11267149 ! melanosome localization GO:0032400 10 7 0,000 0,03781843 0,11252573 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03781843 0,11238034 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03781843 0,11223534 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03781843 0,1120907 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03781843 0,11194644 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03781843 0,11180255 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03781843 0,11165903 ! mast cell activation GO:0045576 9 7 0,000 0,03781843 0,11151588 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03781843 0,11137309 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03781843 0,11123067 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03781843 0,11108862 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03781843 0,11094692 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03781843 0,11080559 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03781843 0,11066461 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03781843 0,110524 ! T cell lineage commitment GO:0002360 12 7 0,000 0,03781843 0,11038374 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03781843 0,11024384 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03781843 0,11010429 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03781843 0,10996509 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03781843 0,10982625 ! response to tumor cell GO:0002347 12 7 0,000 0,03781843 0,10968775 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03781843 0,10954961 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03781843 0,10941181 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03781843 0,10927436 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03781843 0,10913725 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03781843 0,10900048 ! diuresis GO:0030146 12 7 0,000 0,03781843 0,10886406 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03781843 0,10872798 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03781843 0,10859224 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03781843 0,10845684 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03781843 0,10832178 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03781843 0,10818705 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03781843 0,10805265 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03781843 0,10791859 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03781843 0,10778487 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03781843 0,10765147 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03781843 0,1075184 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03781843 0,10738566 ! lymph node development GO:0048535 9 7 0,000 0,03781843 0,10725325 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03781843 0,10712117 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03781843 0,10698941 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03781843 0,10685797 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03781843 0,10672686 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03781843 0,10659606 ! ATP catabolic process GO:0006200 10 7 0,000 0,03781843 0,10646559 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03781843 0,10633544 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03781843 0,1062056 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03781843 0,10607608 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03781843 0,10594688 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03781843 0,10581799 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03781843 0,10568941 ! muscle adaptation GO:0043500 12 7 0,000 0,03781843 0,10556115 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03781843 0,1054332 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03781843 0,10530555 ! retina homeostasis GO:0001895 9 7 0,000 0,03781843 0,10517822 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03781843 0,10505119 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03781843 0,10492447 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03781843 0,10479806 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03781843 0,10467195 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03781843 0,10454614 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03781843 0,10442063 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,03793643 0,10462085 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,03917817 0,10791591 ! carbohydrate transport GO:0008643 74 57 1,000 0,03917817 0,10778682 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,03917817 0,10765804 GO:0048609|reproductive process in a multicellular organism, ! viral reproductive process GO:0022415 87 58 1,000 0,04043526 0,11097982 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,04043526 0,11084755 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,04043526 0,11071559 ! protein maturation by peptide bond cleavage GO:0051605 76 58 1,000 0,04043526 0,11058394 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,0417075 0,11392786 ! activation of MAPK activity GO:0000187 84 59 1,000 0,0417075 0,11379271 ! lung development GO:0030324 94 59 1,000 0,0417075 0,11365789 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,0429947 0,11702699 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,0429947 0,11688866 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04310423 0,1170481 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04310423 0,11691007 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,04310423 0,11677236 ! axon extension GO:0048675 11 8 0,000 0,04310423 0,11663498 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04310423 0,11649793 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04310423 0,11636119 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04310423 0,11622478 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04310423 0,11608868 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04310423 0,11595291 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04310423 0,11581745 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,04310423 0,11568231 ! phosphate transport GO:0006817 10 8 0,000 0,04310423 0,11554748 ! N-glycan processing GO:0006491 12 8 0,000 0,04310423 0,11541297 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04310423 0,11527876 ! UTP metabolic process GO:0046051 8 8 0,000 0,04310423 0,11514487 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04310423 0,1150113 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04310423 0,11487803 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,04310423 0,11474507 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04310423 0,11461241 ! succinate metabolic process GO:0006105 14 8 0,000 0,04310423 0,11448007 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04310423 0,11434802 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04310423 0,11421629 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04310423 0,11408485 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04310423 0,11395372 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04310423 0,11382289 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04310423 0,11369236 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04310423 0,11356213 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04310423 0,11343219 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04310423 0,11330256 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04310423 0,11317322 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04310423 0,11304417 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04310423 0,11291542 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04310423 0,11278696 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04310423 0,11265879 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04310423 0,11253092 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04310423 0,11240333 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04310423 0,11227603 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04310423 0,11214902 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04310423 0,1120223 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04310423 0,11189587 ! melanin metabolic process GO:0006582 12 8 0,000 0,04310423 0,11176971 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04310423 0,11164385 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04310423 0,11151826 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,04310423 0,11139296 ! macrophage activation GO:0042116 12 8 0,000 0,04310423 0,11126794 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04310423 0,1111432 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04310423 0,11101874 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,04310423 0,11089456 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04310423 0,11077066 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04310423 0,11064703 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04310423 0,11052368 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04310423 0,1104006 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04310423 0,11027779 ! ruffle organization GO:0031529 11 8 0,000 0,04310423 0,11015526 ! osteoblast development GO:0002076 13 8 0,000 0,04310423 0,110033 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04310423 0,10991102 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04310423 0,1097893 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04310423 0,10966785 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04310423 0,10954667 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04310423 0,10942576 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04310423 0,10930511 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04310423 0,10918473 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04310423 0,10906462 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04310423 0,10894477 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,04310423 0,10882518 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,04310423 0,10870585 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04310423 0,10858679 ! segment specification GO:0007379 10 8 0,000 0,04310423 0,10846798 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04310423 0,10834944 ! cellular extravasation GO:0045123 11 8 0,000 0,04310423 0,10823115 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04310423 0,10811313 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04310423 0,10799536 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04310423 0,10787784 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,04310423 0,10776058 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04310423 0,10764358 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04310423 0,10752683 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04310423 0,10741033 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04310423 0,10729409 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04310423 0,10717809 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04310423 0,10706235 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04310423 0,10694686 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04310423 0,10683161 ! icosanoid secretion GO:0032309 12 8 0,000 0,04310423 0,10671662 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04310423 0,10660187 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04310423 0,10648737 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04310423 0,10637311 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04310423 0,1062591 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04310423 0,10614533 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04310423 0,1060318 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04310423 0,10591852 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04310423 0,10580548 ! sterol catabolic process GO:0016127 9 8 0,000 0,04310423 0,10569268 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04310423 0,10558012 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04310423 0,10546781 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04310423 0,10535572 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04310423 0,10524388 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04310423 0,10513228 ! prophase GO:0051324 11 8 0,000 0,04310423 0,10502091 ! S phase GO:0051320 8 8 0,000 0,04310423 0,10490977 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04310423 0,10479888 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04310423 0,10468821 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04310423 0,10457778 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04310423 0,10446758 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04310423 0,10435762 ! hormone catabolic process GO:0042447 13 8 0,000 0,04310423 0,10424788 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04310423 0,10413838 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04310423 0,1040291 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04310423 0,10392006 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04310423 0,10381124 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04310423 0,10370265 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04310423 0,10359429 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04310423 0,10348616 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04310423 0,10337824 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04310423 0,10327056 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04310423 0,1031631 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04310423 0,10305586 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04310423 0,10294884 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04310423 0,10284205 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,04310423 0,10273548 ! respiratory tube development GO:0030323 99 62 1,000 0,04561316 0,10860276 ! lymphocyte mediated immunity GO:0002449 88 62 1,000 0,04561316 0,10849045 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,04694403 0,11154057 ! viral reproduction GO:0016032 92 63 1,000 0,04694403 0,11142546 ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,04828907 0,11449986 ! respiratory system development GO:0060541 100 64 1,000 0,04828907 0,11438194 ! adaptive immune response GO:0002250 94 64 1,000 0,04828907 0,11426426 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0483613 0,11431757 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0483613 0,1142002 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,0483613 0,11408307 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,0483613 0,11396618 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,0483613 0,11384953 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,0483613 0,11373312 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0483613 0,11361695 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,0483613 0,11350101 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,0483613 0,11338531 ! GTP metabolic process GO:0046039 9 9 0,000 0,0483613 0,11326985 ! elastic fiber assembly GO:0048251 13 9 0,000 0,0483613 0,11315462 ! social behavior GO:0035176 14 9 0,000 0,0483613 0,11303963 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,0483613 0,11292486 ! artery development GO:0060840 19 9 0,000 0,0483613 0,11281034 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,0483613 0,11269604 ! response to pain GO:0048265 16 9 0,000 0,0483613 0,11258198 ! protein complex disassembly GO:0043241 17 9 0,000 0,0483613 0,11246814 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0483613 0,11235454 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0483613 0,11224116 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,0483613 0,11212802 ! lung alveolus development GO:0048286 17 9 0,000 0,0483613 0,1120151 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0483613 0,11190241 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,0483613 0,11178994 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0483613 0,1116777 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0483613 0,11156569 ! ventral spinal cord development GO:0021517 11 9 0,000 0,0483613 0,1114539 ! protein targeting to ER GO:0045047 19 9 0,000 0,0483613 0,11134233 ! T cell selection GO:0045058 18 9 0,000 0,0483613 0,11123099 ! endoderm development GO:0007492 12 9 0,000 0,0483613 0,11111987 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0483613 0,11100897 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0483613 0,1108983 ! arginine catabolic process GO:0006527 10 9 0,000 0,0483613 0,11078784 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,0483613 0,1106776 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,0483613 0,11056759 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,0483613 0,11045779 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0483613 0,11034821 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,0483613 0,11023884 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,0483613 0,11012969 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,0483613 0,11002076 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,0483613 0,10991205 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0483613 0,10980355 ! mannose metabolic process GO:0006013 9 9 0,000 0,0483613 0,10969526 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,0483613 0,10958718 ! receptor clustering GO:0043113 15 9 0,000 0,0483613 0,10947932 ! epithelial cell development GO:0002064 10 9 0,000 0,0483613 0,10937167 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,0483613 0,10926424 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0483613 0,10915701 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,0483613 0,10904999 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0483613 0,10894318 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,0483613 0,10883659 ! motor axon guidance GO:0008045 14 9 0,000 0,0483613 0,1087302 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,0483613 0,10862402 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,0483613 0,10851804 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,0483613 0,10841227 ! blastoderm segmentation GO:0007350 11 9 0,000 0,0483613 0,10830671 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0483613 0,10820135 ! DNA ligation GO:0006266 14 9 0,000 0,0483613 0,1080962 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,0483613 0,10799125 ! response to amine stimulus GO:0014075 13 9 0,000 0,0483613 0,10788651 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,0483613 0,10778197 ! erythrocyte development GO:0048821 11 9 0,000 0,0483613 0,10767763 ! renal water homeostasis GO:0003091 14 9 0,000 0,0483613 0,10757349 ! postreplication repair GO:0006301 11 9 0,000 0,0483613 0,10746956 ! mRNA cleavage GO:0006379 13 9 0,000 0,0483613 0,10736582 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,0483613 0,10726229 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,0483613 0,10715895 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0483613 0,10705581 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,0483613 0,10695288 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,0483613 0,10685014 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,0483613 0,10674759 ! acid secretion GO:0046717 14 9 0,000 0,0483613 0,10664525 ! musculoskeletal movement GO:0050881 11 9 0,000 0,0483613 0,1065431 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,0483613 0,10644114 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,0483613 0,10633938 ! purine base metabolic process GO:0006144 18 9 0,000 0,0483613 0,10623781 ! oocyte differentiation GO:0009994 12 9 0,000 0,0483613 0,10613644 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,0483613 0,10603526 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,0483613 0,10593428 ! spleen development GO:0048536 15 9 0,000 0,0483613 0,10583348 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,0483613 0,10573288 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,0483613 0,10563247 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,0483613 0,10553225 ! detection of calcium ion GO:0005513 13 9 0,000 0,0483613 0,10543222 ! blastocyst formation GO:0001825 12 9 0,000 0,0483613 0,10533238 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0483613 0,10523273 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,0483613 0,10513326 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,0483613 0,10503399 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0483613 0,1049349 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0483613 0,104836 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,0483613 0,10473728 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,0483613 0,10463875 ! prepulse inhibition GO:0060134 14 9 0,000 0,0483613 0,10454041 ! embryonic placenta development GO:0001892 12 9 0,000 0,0483613 0,10444225 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,0483613 0,10434427 ! insulin secretion GO:0030073 17 9 0,000 0,0483613 0,10424648 ! response to nicotine GO:0035094 16 9 0,000 0,0483613 0,10414887 ! establishment of cell polarity GO:0030010 12 9 0,000 0,0483613 0,10405144 ! regulation of synapse organization GO:0050807 12 9 0,000 0,0483613 0,1039542 ! localization within membrane GO:0051668 15 9 0,000 0,0483613 0,10385714 ! protein oligomerization GO:0051259 100 65 1,000 0,04964808 0,10652108 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,05102088 0,10936443 ! antigen processing and presentation GO:0019882 96 66 1,000 0,05102088 0,1092626 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,05240728 0,1121272 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,05358979 0,11455066 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05358979 0,1144443 ! neuron fate specification GO:0048665 11 10 0,000 0,05358979 0,11433813 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05358979 0,11423217 ! thyroid gland development GO:0030878 19 10 0,000 0,05358979 0,1141264 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,05358979 0,11402082 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05358979 0,11391544 ! synapsis GO:0007129 13 10 0,000 0,05358979 0,11381026 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05358979 0,11370526 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05358979 0,11360047 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05358979 0,11349586 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05358979 0,11339145 ! sulfate transport GO:0008272 12 10 0,000 0,05358979 0,11328723 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05358979 0,1131832 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 13 10 0,000 0,05358979 0,11307936 ! phospholipid efflux GO:0033700 16 10 0,000 0,05358979 0,11297572 ! hippocampus development GO:0021766 19 10 0,000 0,05358979 0,11287226 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,05358979 0,11276899 ! blood vessel remodeling GO:0001974 21 10 0,000 0,05358979 0,11266591 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05358979 0,11256302 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05358979 0,11246032 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05358979 0,1123578 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05358979 0,11225547 ! pathogenesis GO:0009405 13 10 0,000 0,05358979 0,11215333 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05358979 0,11205137 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05358979 0,1119496 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05358979 0,11184801 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,05358979 0,11174661 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,05358979 0,11164539 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05358979 0,11154435 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05358979 0,1114435 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05358979 0,11134282 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05358979 0,11124233 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05358979 0,11114203 ! response to X-ray GO:0010165 16 10 0,000 0,05358979 0,1110419 ! B cell proliferation GO:0042100 14 10 0,000 0,05358979 0,11094195 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05358979 0,11084218 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05358979 0,11074259 ! forebrain cell migration GO:0021885 17 10 0,000 0,05358979 0,11064318 ! lipid digestion GO:0044241 15 10 0,000 0,05358979 0,11054395 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05358979 0,1104449 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05358979 0,11034602 ! UV protection GO:0009650 14 10 0,000 0,05358979 0,11024732 ! entry into host cell GO:0030260 20 10 0,000 0,05358979 0,1101488 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05358979 0,11005045 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05358979 0,10995228 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05358979 0,10985428 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05358979 0,10975646 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,05358979 0,10965881 ! regulation of bone resorption GO:0045124 24 10 0,000 0,05358979 0,10956134 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05358979 0,10946404 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,05358979 0,10936691 ! regulation of organ growth GO:0046620 11 10 0,000 0,05358979 0,10926995 ! response to dsRNA GO:0043331 18 10 0,000 0,05358979 0,10917317 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05358979 0,10907655 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05358979 0,10898011 ! embryonic axis specification GO:0000578 12 10 0,000 0,05358979 0,10888384 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05358979 0,10878774 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05358979 0,1086918 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05358979 0,10859604 ! cranial nerve development GO:0021545 12 10 0,000 0,05358979 0,10850045 ! fucose catabolic process GO:0019317 16 10 0,000 0,05358979 0,10840502 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05358979 0,10830976 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05358979 0,10821467 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05358979 0,10811974 ! zymogen activation GO:0031638 14 10 0,000 0,05358979 0,10802498 ! salivary gland development GO:0007431 22 10 0,000 0,05358979 0,10793039 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05358979 0,10783596 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05358979 0,1077417 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05358979 0,1076476 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05358979 0,10755367 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,05358979 0,1074599 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05358979 0,1073663 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05358979 0,10727285 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05358979 0,10717957 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05358979 0,10708645 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05358979 0,1069935 ! detection of bacterium GO:0016045 10 10 0,000 0,05358979 0,1069007 ! embryonic gut development GO:0048566 11 10 0,000 0,05358979 0,10680806 ! activation of innate immune response GO:0002218 10 10 0,000 0,05358979 0,10671559 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05358979 0,10662328 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05358979 0,10653112 ! developmental induction GO:0031128 13 10 0,000 0,05358979 0,10643912 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,05358979 0,10634729 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05358979 0,10625561 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05358979 0,10616409 ! rhythmic process GO:0048511 105 68 1,000 0,05380709 0,10650284 ! response to drug GO:0042493 108 69 1,000 0,05522011 0,10920573 ! humoral immune response GO:0006959 86 70 1,000 0,05664618 0,11192974 ! regulation of catabolic process GO:0009894 106 70 1,000 0,05664618 0,11183367 ! leukocyte mediated immunity GO:0002443 99 71 1,000 0,05808511 0,11457612 ! steroid biosynthetic process GO:0006694 94 71 1,000 0,05808511 0,11447794 ! rRNA transcription GO:0009303 17 11 0,000 0,05878984 0,11576767 ! respiratory burst GO:0045730 14 11 0,000 0,05878984 0,11566864 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05878984 0,11556977 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05878984 0,11547108 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,05878984 0,11537256 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,05878984 0,1152742 GO:0000725|recombinational repair, ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05878984 0,11517601 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05878984 0,11507799 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,05878984 0,11498013 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 14 11 0,000 0,05878984 0,11488244 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,05878984 0,11478492 ! T cell proliferation GO:0042098 20 11 0,000 0,05878984 0,11468756 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05878984 0,11459037 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,05878984 0,11449334 ! bone resorption GO:0045453 16 11 0,000 0,05878984 0,11439648 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05878984 0,11429978 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05878984 0,11420324 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05878984 0,11410687 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,05878984 0,11401065 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05878984 0,1139146 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,05878984 0,11381872 ! syncytium formation GO:0006949 15 11 0,000 0,05878984 0,11372299 ! plasma membrane organization GO:0007009 18 11 0,000 0,05878984 0,11362743 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05878984 0,11353202 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05878984 0,11343678 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05878984 0,11334169 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,05878984 0,11324676 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05878984 0,113152 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05878984 0,11305739 ! adult heart development GO:0007512 11 11 0,000 0,05878984 0,11296294 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05878984 0,11286864 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,05878984 0,11277451 ! temperature homeostasis GO:0001659 16 11 0,000 0,05878984 0,11268053 ! L-glutamate transport GO:0015813 16 11 0,000 0,05878984 0,11258671 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05878984 0,11249304 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05878984 0,11239953 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05878984 0,11230618 ! stem cell development GO:0048864 29 11 0,000 0,05878984 0,11221298 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05878984 0,11211993 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05878984 0,11202704 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05878984 0,1119343 ! vasoconstriction GO:0042310 15 11 0,000 0,05878984 0,11184172 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05878984 0,11174929 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05878984 0,11165701 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05878984 0,11156488 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05878984 0,11147291 ! ribosome assembly GO:0042255 13 11 0,000 0,05878984 0,11138108 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05878984 0,11128941 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05878984 0,11119789 ! chromatin silencing GO:0006342 19 11 0,000 0,05878984 0,11110652 ! nucleosome positioning GO:0016584 13 11 0,000 0,05878984 0,1110153 ! T cell homeostasis GO:0043029 20 11 0,000 0,05878984 0,11092423 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05878984 0,11083331 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,05878984 0,11074254 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05878984 0,11065191 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05878984 0,11056144 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05878984 0,11047111 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,05878984 0,11038093 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05878984 0,11029089 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05878984 0,11020101 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05878984 0,11011127 ! male genitalia development GO:0030539 13 11 0,000 0,05878984 0,11002167 ! cholesterol efflux GO:0033344 19 11 0,000 0,05878984 0,10993222 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05878984 0,10984292 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,05878984 0,10975376 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05878984 0,10966475 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05878984 0,10957588 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05878984 0,10948715 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05878984 0,10939857 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,05878984 0,10931013 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,05878984 0,10922184 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05878984 0,10913369 ! lysogeny GO:0030069 18 11 0,000 0,05878984 0,10904567 GO:0019047|provirus integration, ! acrosome reaction GO:0007340 13 11 0,000 0,05878984 0,1089578 ! response to hypoxia GO:0001666 132 72 1,000 0,05953671 0,11025317 ! response to oxygen levels GO:0070482 137 74 1,000 0,06247723 0,1156055 ! lactation GO:0007595 20 12 0,000 0,06396162 0,11825702 ! reproductive cellular process GO:0048610 14 12 0,000 0,06396162 0,11816203 ! tRNA modification GO:0006400 14 12 0,000 0,06396162 0,1180672 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,06396162 0,11797252 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06396162 0,11787799 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06396162 0,11778361 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06396162 0,11768938 ! non-recombinational repair GO:0000726 19 12 0,000 0,06396162 0,11759531 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06396162 0,11750138 ! peroxisomal transport GO:0043574 21 12 0,000 0,06396162 0,11740761 ! cartilage condensation GO:0001502 18 12 0,000 0,06396162 0,11731398 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06396162 0,1172205 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06396162 0,11712717 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06396162 0,11703399 ! heart looping GO:0001947 15 12 0,000 0,06396162 0,11694096 ! palate development GO:0060021 15 12 0,000 0,06396162 0,11684808 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06396162 0,11675534 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,06396162 0,11666275 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06396162 0,11657031 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06396162 0,11647801 ! arginine metabolic process GO:0006525 13 12 0,000 0,06396162 0,11638586 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06396162 0,11629386 ! methionine metabolic process GO:0006555 13 12 0,000 0,06396162 0,116202 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06396162 0,11611028 ! Golgi organization GO:0007030 18 12 0,000 0,06396162 0,11601872 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06396162 0,11592729 ! monoamine transport GO:0015844 13 12 0,000 0,06396162 0,11583601 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06396162 0,11574487 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06396162 0,11565388 ! L-amino acid transport GO:0015807 20 12 0,000 0,06396162 0,11556302 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06396162 0,11547232 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06396162 0,11538175 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06396162 0,11529133 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06396162 0,11520104 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06396162 0,1151109 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06396162 0,1150209 ! cerebellum development GO:0021549 13 12 0,000 0,06396162 0,11493104 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06396162 0,11484132 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06396162 0,11475174 ! histone methylation GO:0016571 15 12 0,000 0,06396162 0,1146623 ! autonomic nervous system development GO:0048483 23 12 0,000 0,06396162 0,114573 ! gland morphogenesis GO:0022612 23 12 0,000 0,06396162 0,11448384 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06396162 0,11439481 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06396162 0,11430593 ! response to gamma radiation GO:0010332 20 12 0,000 0,06396162 0,11421718 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06396162 0,11412857 ! intestinal absorption GO:0050892 19 12 0,000 0,06396162 0,1140401 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06396162 0,11395177 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06396162 0,11386357 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,06396162 0,11377551 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06396162 0,11368758 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,06396162 0,11359979 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06396162 0,11351214 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06396162 0,11342462 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06396162 0,11333723 ! response to cold GO:0009409 14 12 0,000 0,06396162 0,11324999 ! regulation of protein transport GO:0051223 114 76 1,000 0,06546633 0,11582504 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 110 77 1,000 0,06697865 0,11840961 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,06697865 0,11831867 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06910528 0,12198169 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06910528 0,12188815 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06910528 0,12179474 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06910528 0,12170149 ! water transport GO:0006833 17 13 0,000 0,06910528 0,12160837 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06910528 0,1215154 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06910528 0,12142257 ! lipid localization GO:0010876 24 13 0,000 0,06910528 0,12132988 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06910528 0,12123733 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06910528 0,12114492 ! organelle fusion GO:0048284 28 13 0,000 0,06910528 0,12105266 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06910528 0,12096053 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06910528 0,12086855 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,06910528 0,1207767 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06910528 0,120685 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06910528 0,12059343 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06910528 0,120502 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06910528 0,12041071 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06910528 0,12031956 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06910528 0,12022855 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06910528 0,12013767 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06910528 0,12004693 ! NAD metabolic process GO:0019674 21 13 0,000 0,06910528 0,11995633 ! exocrine system development GO:0035272 27 13 0,000 0,06910528 0,11986587 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06910528 0,11977554 ! bone mineralization GO:0030282 15 13 0,000 0,06910528 0,11968535 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06910528 0,11959529 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,06910528 0,11950537 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06910528 0,11941558 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06910528 0,11932593 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06910528 0,11923642 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06910528 0,11914703 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,06910528 0,11905778 ! genitalia development GO:0048806 15 13 0,000 0,06910528 0,11896867 ! regulation of cellular pH GO:0030641 20 13 0,000 0,06910528 0,11887969 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,06910528 0,11879084 ! tissue regeneration GO:0042246 21 13 0,000 0,06910528 0,11870212 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06910528 0,11861354 ! cofactor transport GO:0051181 19 13 0,000 0,06910528 0,11852509 ! NADP metabolic process GO:0006739 18 13 0,000 0,06910528 0,11843677 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06910528 0,11834858 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06910528 0,11826052 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06910528 0,1181726 ! gas transport GO:0015669 18 13 0,000 0,06910528 0,1180848 ! regulation of RNA stability GO:0043487 28 13 0,000 0,06910528 0,11799714 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06910528 0,1179096 ! regulation of axon extension GO:0030516 23 13 0,000 0,06910528 0,1178222 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06910528 0,11773492 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06910528 0,11764777 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06910528 0,11756076 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06910528 0,11747387 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06910528 0,11738711 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06910528 0,11730047 ! T cell activation GO:0042110 134 79 1,000 0,07003801 0,11879603 ! forebrain development GO:0030900 131 80 1,000 0,0715847 0,12133 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,07314251 0,12387906 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,07422096 0,12561311 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,07422096 0,12552075 ! superoxide anion generation GO:0042554 18 14 0,000 0,07422096 0,12542852 ! neuron maturation GO:0042551 21 14 0,000 0,07422096 0,12533643 ! regulation of S phase GO:0033261 18 14 0,000 0,07422096 0,12524447 ! myotube differentiation GO:0014902 21 14 0,000 0,07422096 0,12515265 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,07422096 0,12506096 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,07422096 0,12496941 ! inositol metabolic process GO:0006020 20 14 0,000 0,07422096 0,12487799 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,07422096 0,12478671 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,07422096 0,12469556 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,07422096 0,12460454 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,07422096 0,12451365 ! gene silencing by RNA GO:0031047 20 14 0,000 0,07422096 0,1244229 ! response to cAMP GO:0051591 19 14 0,000 0,07422096 0,12433228 ! startle response GO:0001964 21 14 0,000 0,07422096 0,12424179 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,07422096 0,12415143 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,07422096 0,1240612 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,07422096 0,12397111 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,07422096 0,12388114 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,07422096 0,12379131 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,07422096 0,12370161 ! glycine metabolic process GO:0006544 22 14 0,000 0,07422096 0,12361203 ! cellular response to starvation GO:0009267 21 14 0,000 0,07422096 0,12352259 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,07422096 0,12343327 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,07422096 0,12334409 ! regulation of heart rate GO:0002027 23 14 0,000 0,07422096 0,12325503 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,07422096 0,1231661 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,07422096 0,1230773 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,07422096 0,12298863 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,07422096 0,12290008 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,07422096 0,12281167 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,07422096 0,12272338 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,07422096 0,12263521 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,07422096 0,12254718 ! axon cargo transport GO:0008088 27 14 0,000 0,07422096 0,12245927 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,07422096 0,12237148 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,07422096 0,12228382 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,07422096 0,12219629 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,07422096 0,12210888 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07422096 0,1220216 ! mRNA splice site selection GO:0006376 26 14 0,000 0,07422096 0,12193444 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,07422096 0,12184741 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,07422096 0,1217605 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,07422096 0,12167371 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,07422096 0,12158705 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,07422096 0,12150051 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,07422096 0,12141409 ! muscle maintenance GO:0046716 19 14 0,000 0,07422096 0,1213278 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,07422096 0,12124163 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,07422096 0,12115558 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,07422096 0,12106966 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,07422096 0,12098385 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,07422096 0,12089817 ! cilium assembly GO:0042384 20 14 0,000 0,07422096 0,12081261 ! peptide hormone secretion GO:0030072 23 14 0,000 0,07422096 0,12072717 ! detection of stimulus GO:0051606 108 82 1,000 0,07471127 0,12143881 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07930883 0,12882083 ! positive regulation of cell size GO:0045793 20 15 0,000 0,07930883 0,12872992 ! metencephalon development GO:0022037 19 15 0,000 0,07930883 0,12863914 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07930883 0,12854849 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07930883 0,12845796 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,07930883 0,12836756 ! skin development GO:0043588 25 15 0,000 0,07930883 0,12827729 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07930883 0,12818714 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,07930883 0,12809712 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,07930883 0,12800723 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07930883 0,12791746 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07930883 0,12782782 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07930883 0,12773831 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07930883 0,12764892 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07930883 0,12755965 ! adult walking behavior GO:0007628 25 15 0,000 0,07930883 0,12747051 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07930883 0,12738149 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,07930883 0,1272926 ! myoblast differentiation GO:0045445 27 15 0,000 0,07930883 0,12720384 ! centrosome cycle GO:0007098 16 15 0,000 0,07930883 0,12711519 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07930883 0,12702667 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07930883 0,12693827 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07930883 0,12685 ! cerebral cortex development GO:0021987 29 15 0,000 0,07930883 0,12676185 ! response to osmotic stress GO:0006970 22 15 0,000 0,07930883 0,12667382 ! vesicle coating GO:0006901 25 15 0,000 0,07930883 0,12658591 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07930883 0,12649813 ! DNA integration GO:0015074 22 15 0,000 0,07930883 0,12641046 ! peptide secretion GO:0002790 27 15 0,000 0,07930883 0,12632292 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07930883 0,1262355 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07930883 0,1261482 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07930883 0,12606102 ! neuron recognition GO:0008038 22 15 0,000 0,07930883 0,12597396 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,07930883 0,12588703 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07930883 0,12580021 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,07930883 0,12571351 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07930883 0,12562693 ! biomineral formation GO:0031214 18 15 0,000 0,07930883 0,12554047 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07930883 0,12545413 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,07930883 0,1253679 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07930883 0,1252818 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07930883 0,12519581 ! organic cation transport GO:0015695 19 15 0,000 0,07930883 0,12510995 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07930883 0,12502419 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07930883 0,12493856 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,07930883 0,12485305 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,07930883 0,12476765 ! defense response to virus GO:0051607 27 15 0,000 0,07930883 0,12468237 ! peptide hormone processing GO:0016486 19 15 0,000 0,07930883 0,1245972 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07930883 0,12451215 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,07948162 0,12469832 ! transcription initiation GO:0006352 118 85 1,000 0,07948162 0,12461332 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,07948162 0,12452843 ! regulation of protein localization GO:0032880 132 85 1,000 0,07948162 0,12444366 ! regulation of membrane potential GO:0042391 128 85 1,000 0,07948162 0,124359 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,08271365 0,12932793 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,08271365 0,12924008 ! protein secretion GO:0009306 27 16 0,000 0,08436902 0,13173709 ! hormone secretion GO:0046879 25 16 0,000 0,08436902 0,13164772 ! bone remodeling GO:0046849 24 16 0,000 0,08436902 0,13155847 ! endothelial cell migration GO:0043542 22 16 0,000 0,08436902 0,13146934 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,08436902 0,13138032 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08436902 0,13129143 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,08436902 0,13120266 ! glial cell development GO:0021782 24 16 0,000 0,08436902 0,13111401 ! patterning of blood vessels GO:0001569 24 16 0,000 0,08436902 0,13102548 ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,08436902 0,13093707 ! protein polyubiquitination GO:0000209 26 16 0,000 0,08436902 0,13084878 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,08436902 0,13076061 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,08436902 0,13067255 ! fructose metabolic process GO:0006000 20 16 0,000 0,08436902 0,13058462 ! regulation of protein binding GO:0043393 27 16 0,000 0,08436902 0,1304968 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,08436902 0,1304091 ! negative regulation of immune response GO:0050777 28 16 0,000 0,08436902 0,13032152 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,08436902 0,13023405 ! DNA replication initiation GO:0006270 25 16 0,000 0,08436902 0,13014671 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,08436902 0,13005948 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,08436902 0,12997236 ! oogenesis GO:0048477 23 16 0,000 0,08436902 0,12988537 ! neural crest cell migration GO:0001755 24 16 0,000 0,08436902 0,12979849 ! G1 phase GO:0051318 27 16 0,000 0,08436902 0,12971172 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,08436902 0,12962508 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,08436902 0,12953854 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,08436902 0,12945213 ! steroid catabolic process GO:0006706 22 16 0,000 0,08436902 0,12936583 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,08436902 0,12927964 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,08436902 0,12919357 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,08436902 0,12910761 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,08436902 0,12902177 ! sperm-egg recognition GO:0035036 16 16 0,000 0,08436902 0,12893604 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,08436902 0,12885042 ! nerve development GO:0021675 18 16 0,000 0,08436902 0,12876492 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,08436902 0,12867954 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,08598563 0,13105828 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08940168 0,13617475 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08940168 0,13608463 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08940168 0,13599463 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08940168 0,13590474 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,08940168 0,13581498 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08940168 0,13572533 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08940168 0,1356358 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08940168 0,13554639 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08940168 0,1354571 ! signal complex assembly GO:0007172 29 17 0,000 0,08940168 0,13536792 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08940168 0,13527887 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08940168 0,13518992 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08940168 0,1351011 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,08940168 0,13501239 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08940168 0,1349238 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08940168 0,13483533 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08940168 0,13474697 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08940168 0,13465873 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,08940168 0,1345706 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08940168 0,13448259 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08940168 0,13439469 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08940168 0,13430691 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08940168 0,13421924 ! membrane budding GO:0006900 29 17 0,000 0,08940168 0,13413169 ! heme metabolic process GO:0042168 27 17 0,000 0,08940168 0,13404425 ! neuromuscular junction development GO:0007528 23 17 0,000 0,08940168 0,13395692 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,08940168 0,13386971 ! body fluid secretion GO:0007589 27 17 0,000 0,08940168 0,13378261 ! stem cell differentiation GO:0048863 36 17 0,000 0,08940168 0,13369563 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08940168 0,13360876 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08940168 0,133522 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08940168 0,13343535 ! sensory perception of pain GO:0019233 23 17 0,000 0,08940168 0,13334882 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08940168 0,13326239 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08940168 0,13317608 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,08940168 0,13308989 ! synaptogenesis GO:0007416 24 17 0,000 0,08940168 0,1330038 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08940168 0,13291782 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08940168 0,13283196 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08940168 0,13274621 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,08940168 0,13266056 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,08940168 0,13257503 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,08940168 0,13248961 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08940168 0,1324043 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,08940168 0,1323191 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,0909658 0,13454748 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,0926445 0,13694238 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,0926445 0,13685443 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,09440698 0,13936845 ! positive regulation of translation GO:0045727 28 18 0,000 0,09440698 0,13927906 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,09440698 0,13918977 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,09440698 0,13910061 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,09440698 0,13901155 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,09440698 0,13892262 ! cAMP metabolic process GO:0046058 33 18 0,000 0,09440698 0,13883379 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,09440698 0,13874508 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,09440698 0,13865648 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,09440698 0,138568 ! axis specification GO:0009798 26 18 0,000 0,09440698 0,13847962 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,09440698 0,13839136 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,09440698 0,13830322 ! pancreas development GO:0031016 26 18 0,000 0,09440698 0,13821518 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,09440698 0,13812726 ! glutamine metabolic process GO:0006541 23 18 0,000 0,09440698 0,13803945 ! response to retinoic acid GO:0032526 25 18 0,000 0,09440698 0,13795175 ! pigmentation during development GO:0048066 31 18 0,000 0,09440698 0,13786416 ! central nervous system neuron development GO:0021954 30 18 0,000 0,09440698 0,13777668 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,09440698 0,13768931 ! fucose metabolic process GO:0006004 26 18 0,000 0,09440698 0,13760206 ! response to fungus GO:0009620 19 18 0,000 0,09440698 0,13751491 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,09440698 0,13742788 ! heart process GO:0003015 27 18 0,000 0,09440698 0,13734095 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,09440698 0,13725414 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,09440698 0,13716743 ! visual learning GO:0008542 35 18 0,000 0,09440698 0,13708084 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,09440698 0,13699435 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,09440698 0,13690797 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,09440698 0,13682171 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,09440698 0,13673555 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,09440698 0,1366495 ! vitamin transport GO:0051180 24 18 0,000 0,09440698 0,13656355 ! hormone transport GO:0009914 27 18 0,000 0,09440698 0,13647772 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,09440698 0,13639199 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,09440698 0,13630637 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,09440698 0,13622086 ! cell-cell recognition GO:0009988 20 18 0,000 0,09440698 0,13613545 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,09440698 0,13605016 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,09440698 0,13596496 ! regulation of glucose import GO:0046324 21 18 0,000 0,09440698 0,13587988 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,09440698 0,1357949 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,09440698 0,13571003 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,09440698 0,13562526 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,09440698 0,1355406 ! in utero embryonic development GO:0001701 147 96 1,000 0,09773446 0,14023035 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,09938504 0,14250972 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,09938504 0,14242093 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,09938504 0,14233225 ! positive regulation of ossification GO:0045778 30 19 0,000 0,09938504 0,14224368 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,09938504 0,14215522 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,09938504 0,14206687 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,09938504 0,14197863 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,09938504 0,1418905 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,09938504 0,14180248 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,09938504 0,14171457 ! regeneration GO:0031099 32 19 0,000 0,09938504 0,14162676 ! sensory perception of taste GO:0050909 23 19 0,000 0,09938504 0,14153907 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,09938504 0,14145148 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,09938504 0,14136401 ! smooth muscle contraction GO:0006939 36 19 0,000 0,09938504 0,14127664 ! peroxisome organization GO:0007031 29 19 0,000 0,09938504 0,14118938 ! digestive system process GO:0022600 30 19 0,000 0,09938504 0,14110222 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,09938504 0,14101517 ! response to vitamin A GO:0033189 26 19 0,000 0,09938504 0,14092824 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,09938504 0,1408414 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,09938504 0,14075468 ! response to starvation GO:0042594 30 19 0,000 0,09938504 0,14066806 ! plasma membrane fusion GO:0045026 23 19 0,000 0,09938504 0,14058155 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,09938504 0,14049514 ! renal system process GO:0003014 35 19 0,000 0,09938504 0,14040884 ! vasodilation GO:0042311 33 19 0,000 0,09938504 0,14032265 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,09938504 0,14023656 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,09938504 0,14015058 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,09938504 0,1400647 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,09938504 0,13997893 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,09938504 0,13989327 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,09938504 0,13980771 ! sarcomere organization GO:0045214 23 19 0,000 0,09938504 0,13972225 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,09938504 0,1396369 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,09938504 0,13955165 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,09938504 0,1394665 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,09938504 0,13938146 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,09938504 0,13929653 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,09938504 0,13921169 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,09938504 0,13912696 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,10433603 0,14596889 ! iron ion transport GO:0006826 37 20 0,000 0,10433603 0,14588016 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,10433603 0,14579153 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,10433603 0,14570301 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,10433603 0,1456146 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,10433603 0,1455263 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,10433603 0,1454381 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,10433603 0,14535001 ! spinal cord development GO:0021510 31 20 0,000 0,10433603 0,14526202 ! response to ethanol GO:0045471 37 20 0,000 0,10433603 0,14517414 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,10433603 0,14508637 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,10433603 0,14499871 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,10433603 0,14491115 ! chromosome condensation GO:0030261 31 20 0,000 0,10433603 0,14482369 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,10433603 0,14473635 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,10433603 0,1446491 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,10433603 0,14456196 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,10433603 0,14447493 ! pallium development GO:0021543 38 20 0,000 0,10433603 0,144388 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,10433603 0,14430118 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,10433603 0,14421446 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,10433603 0,14412784 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,10433603 0,14404133 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,10433603 0,14395493 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,10433603 0,14386862 ! collagen catabolic process GO:0030574 25 20 0,000 0,10433603 0,14378242 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,10433603 0,14369632 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,10433603 0,14361033 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,10433603 0,14352444 ! alditol metabolic process GO:0019400 24 20 0,000 0,10433603 0,14343865 ! actin filament-based movement GO:0030048 34 20 0,000 0,10433603 0,14335296 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,1046413 0,14368656 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,10926008 0,14993924 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,10926008 0,14984984 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,10926008 0,14976053 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,10926008 0,14967134 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,10926008 0,14958225 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,10926008 0,14949326 GO:0009799|determination of symmetry, ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,10926008 0,14940438 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,10926008 0,14931561 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,10926008 0,14922694 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,10926008 0,14913838 ! vesicle docking GO:0048278 27 21 0,000 0,10926008 0,14904993 ! phototransduction GO:0007602 25 21 0,000 0,10926008 0,14896157 ! dendrite development GO:0016358 35 21 0,000 0,10926008 0,14887333 ! visual behavior GO:0007632 39 21 0,000 0,10926008 0,14878518 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,10926008 0,14869714 ! ovarian follicle development GO:0001541 30 21 0,000 0,10926008 0,14860921 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,10926008 0,14852138 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,10926008 0,14843365 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,10926008 0,14834603 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,10926008 0,14825851 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,10926008 0,14817109 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,10926008 0,14808378 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,10926008 0,14799657 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,10926008 0,14790946 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,10926008 0,14782246 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,10926008 0,14773555 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,10926008 0,14764875 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,10926008 0,14756205 ! fatty acid transport GO:0015908 30 21 0,000 0,10926008 0,14747545 ! immunoglobulin production GO:0002377 33 21 0,000 0,10926008 0,14738896 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,10926008 0,14730256 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,10926008 0,14721627 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,10926008 0,14713008 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,10926008 0,14704399 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,10926008 0,146958 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,10926008 0,14687211 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,10926008 0,14678632 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,10926008 0,14670063 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,10926008 0,14661504 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,10926008 0,14652955 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,10926008 0,14644416 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,10926008 0,14635887 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,10926008 0,14627368 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,10926008 0,14618858 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,10926008 0,14610359 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,11415733 0,15256355 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,11415733 0,15247495 ! regulation of fibroblast proliferation GO:0048145 35 22 0,000 0,11415733 0,15238646 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,11415733 0,15229807 ! viral genome replication GO:0019079 29 22 0,000 0,11415733 0,15220978 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,11415733 0,15212159 ! leukocyte adhesion GO:0007159 38 22 0,000 0,11415733 0,15203351 ! molting cycle process GO:0022404 40 22 0,000 0,11415733 0,15194553 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,11415733 0,15185765 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,11415733 0,15176987 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,11415733 0,15168219 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,11415733 0,15159461 ! vasculogenesis GO:0001570 33 22 0,000 0,11415733 0,15150714 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,11415733 0,15141976 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,11415733 0,15133249 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,11415733 0,15124532 ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,11415733 0,15115824 ! lysosome organization GO:0007040 37 22 0,000 0,11415733 0,15107127 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,11415733 0,1509844 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,11415733 0,15089763 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,11415733 0,15081095 ! regulation of behavior GO:0050795 38 22 0,000 0,11415733 0,15072438 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,11415733 0,15063791 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,11415733 0,15055153 ! membrane depolarization GO:0051899 35 22 0,000 0,11415733 0,15046525 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,11415733 0,15037908 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,11415733 0,150293 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,11415733 0,15020702 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,11415733 0,15012114 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,11415733 0,15003535 ! blastocyst development GO:0001824 37 22 0,000 0,11415733 0,14994967 ! neural tube closure GO:0001843 33 22 0,000 0,11415733 0,14986408 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,11415733 0,14977859 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,11902795 0,15607998 ! neuron fate commitment GO:0048663 32 23 0,000 0,11902795 0,15599104 ! embryonic pattern specification GO:0009880 31 23 0,000 0,11902795 0,15590221 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,11902795 0,15581348 ! myelination GO:0042552 35 23 0,000 0,11902795 0,15572485 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,11902795 0,15563631 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,11902795 0,15554789 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,11902795 0,15545956 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,11902795 0,15537133 ! vesicle targeting GO:0006903 32 23 0,000 0,11902795 0,1552832 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,11902795 0,15519517 ! osteoblast differentiation GO:0001649 40 23 0,000 0,11902795 0,15510724 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,11902795 0,15501941 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,11902795 0,15493168 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,11902795 0,15484405 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,11902795 0,15475652 ! negative regulation of phosphorylation GO:0042326 41 23 0,000 0,11902795 0,15466908 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,11902795 0,15458175 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,11902795 0,15449451 ! cell fate determination GO:0001709 45 23 0,000 0,11902795 0,15440738 ! pentose metabolic process GO:0019321 31 23 0,000 0,11902795 0,15432034 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,11902795 0,1542334 ! spermatid development GO:0007286 33 23 0,000 0,11902795 0,15414655 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,11902795 0,15405981 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,11902795 0,15397316 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,11902795 0,15388661 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,11902795 0,15380016 ! telomere organization GO:0032200 32 23 0,000 0,11902795 0,1537138 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,11902795 0,15362754 ! regulation of amine transport GO:0051952 38 23 0,000 0,11902795 0,15354138 ! liver development GO:0001889 40 23 0,000 0,11902795 0,15345531 ! initiation of viral infection GO:0019059 42 24 0,000 0,12387206 0,15961105 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,12387206 0,15952169 ! superoxide metabolic process GO:0006801 32 24 0,000 0,12387206 0,15943242 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,12387206 0,15934325 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,12387206 0,15925418 ! fat cell differentiation GO:0045444 37 24 0,000 0,12387206 0,15916521 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,12387206 0,15907634 ! sperm motility GO:0030317 27 24 0,000 0,12387206 0,15898757 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,12387206 0,1588989 ! vacuole organization GO:0007033 39 24 0,000 0,12387206 0,15881033 ! receptor metabolic process GO:0043112 37 24 0,000 0,12387206 0,15872186 ! neural crest cell development GO:0014032 39 24 0,000 0,12387206 0,15863348 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,12387206 0,1585452 ! primary neural tube formation GO:0014020 35 24 0,000 0,12387206 0,15845702 ! negative regulation of cell development GO:0010721 56 24 0,000 0,12387206 0,15836894 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,12387206 0,15828096 ! base-excision repair GO:0006284 31 24 0,000 0,12387206 0,15819308 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,12387206 0,15810529 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,12387206 0,1580176 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,12387206 0,15793001 ! glutathione metabolic process GO:0006749 29 24 0,000 0,12387206 0,15784251 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,12387206 0,15775511 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,12387206 0,15766781 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,12387206 0,1575806 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,12868981 0,16361888 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,12868981 0,16352848 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,12868981 0,16343819 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,12868981 0,16334799 GO:0006479|protein amino acid methylation, ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,12868981 0,16325789 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 0,000 0,12868981 0,16316789 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,12868981 0,16307799 ! peptide transport GO:0015833 43 25 0,000 0,12868981 0,16298819 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,12868981 0,16289849 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,12868981 0,16280889 ! phospholipid transport GO:0015914 35 25 0,000 0,12868981 0,16271938 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,12868981 0,16262998 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,12868981 0,16254067 ! detection of light stimulus GO:0009583 30 25 0,000 0,12868981 0,16245146 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,12868981 0,16236235 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,12868981 0,16227333 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,12868981 0,16218441 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,13348134 0,16813093 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,13348134 0,16803891 ! translational initiation GO:0006413 43 26 0,000 0,13348134 0,16794698 ! regulation of pH GO:0006885 36 26 0,000 0,13348134 0,16785516 ! circadian rhythm GO:0007623 42 26 0,000 0,13348134 0,16776343 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,13348134 0,16767181 ! post-embryonic development GO:0009791 42 26 0,000 0,13348134 0,16758028 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,13348134 0,16748886 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,13348134 0,16739754 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,13348134 0,16730631 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,13348134 0,16721519 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,13348134 0,16712416 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,13348134 0,16703323 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,13348134 0,1669424 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,13348134 0,16685167 ! regulation of coagulation GO:0050818 39 26 0,000 0,13348134 0,16676104 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,13824679 0,17262086 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,13824679 0,1725272 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,13824679 0,17243364 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,13824679 0,17234018 ! membrane docking GO:0022406 39 27 0,000 0,13824679 0,17224682 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,13824679 0,17215356 ! catechol metabolic process GO:0009712 43 27 0,000 0,13824679 0,1720604 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,13824679 0,17196735 ! myofibril assembly GO:0030239 36 27 0,000 0,13824679 0,17187439 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,13824679 0,17178154 ! response to ionizing radiation GO:0010212 47 27 0,000 0,13824679 0,17168878 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,13824679 0,17159613 ! natural killer cell activation GO:0030101 35 27 0,000 0,13824679 0,17150358 ! lipid oxidation GO:0034440 38 27 0,000 0,13824679 0,17141112 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,13824679 0,17131877 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,13824679 0,17122651 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,13824679 0,17113435 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,13824679 0,1710423 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,13824679 0,17095034 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,13824679 0,17085848 ! gene silencing GO:0016458 41 27 0,000 0,13824679 0,17076672 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,14298631 0,17652631 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,14298631 0,17643161 ! phenol metabolic process GO:0018958 44 28 0,000 0,14298631 0,17633701 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,14298631 0,17624251 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,14298631 0,17614811 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,14298631 0,17605381 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,14298631 0,17595962 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,14298631 0,17586552 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,14298631 0,17577152 ! response to organic cyclic substance GO:0014070 47 28 0,000 0,14298631 0,17567763 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,14298631 0,17558383 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,14298631 0,17549014 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,14298631 0,17539655 ! mesoderm formation GO:0001707 46 28 0,000 0,14298631 0,17530305 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,14298631 0,17520965 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,14298631 0,17511636 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,14298631 0,17502316 ! ensheathment of neurons GO:0007272 43 28 0,000 0,14298631 0,17493007 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,14298631 0,17483707 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,14298631 0,17474417 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,14298631 0,17465137 ! neural tube formation GO:0001841 41 28 0,000 0,14298631 0,17455866 ! placenta development GO:0001890 37 28 0,000 0,14298631 0,17446606 ! regulation of B cell activation GO:0050864 42 28 0,000 0,14298631 0,17437355 ! regulation of innate immune response GO:0045088 38 29 0,000 0,14770004 0,18002654 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,14770004 0,17993119 ! protein targeting to membrane GO:0006612 53 29 0,000 0,14770004 0,17983594 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,14770004 0,17974079 ! mismatch repair GO:0006298 34 29 0,000 0,14770004 0,17964573 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,14770004 0,17955078 ! muscle cell development GO:0055001 38 29 0,000 0,14770004 0,17945593 ! formation of primary germ layer GO:0001704 48 29 0,000 0,14770004 0,17936118 ! telencephalon development GO:0021537 52 29 0,000 0,14770004 0,17926654 ! eye morphogenesis GO:0048592 51 29 0,000 0,14770004 0,17917199 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,14770004 0,17907754 ! tissue homeostasis GO:0001894 42 29 0,000 0,14770004 0,17898318 GO:0048871|multicellular organismal homeostasis, ! collagen metabolic process GO:0032963 40 30 0,000 0,1523881 0,18456695 ! organic anion transport GO:0015711 51 30 0,000 0,1523881 0,18446981 ! cholesterol transport GO:0030301 46 30 0,000 0,1523881 0,18437277 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,1523881 0,18427583 ! spliceosome assembly GO:0000245 49 30 0,000 0,1523881 0,184179 ! spindle organization GO:0007051 37 30 0,000 0,1523881 0,18408227 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,1523881 0,18398563 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,1523881 0,1838891 ! ceramide metabolic process GO:0006672 43 30 0,000 0,1523881 0,18379268 ! hindbrain development GO:0030902 45 30 0,000 0,1523881 0,18369635 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,1523881 0,18360012 ! adult locomotory behavior GO:0008344 47 30 0,000 0,1523881 0,183504 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,1523881 0,18340797 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,1523881 0,18331205 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,1523881 0,18321622 ! response to heat GO:0009408 41 30 0,000 0,1523881 0,1831205 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,1523881 0,18302487 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,1523881 0,18292935 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,15705065 0,18842801 ! negative regulation of secretion GO:0051048 49 31 0,000 0,15705065 0,18832976 ! mammary gland development GO:0030879 57 31 0,000 0,15705065 0,18823162 ! glial cell differentiation GO:0010001 55 31 0,000 0,15705065 0,18813359 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,15705065 0,18803565 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,15705065 0,18793782 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,15705065 0,18784009 ! odontogenesis GO:0042476 50 31 0,000 0,15705065 0,18774246 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,15705065 0,18764493 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,15705065 0,1875475 ! metanephros development GO:0001656 58 31 0,000 0,15705065 0,18745018 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,15705065 0,18735295 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,15705065 0,18725583 ! cell fate specification GO:0001708 37 31 0,000 0,15705065 0,1871588 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,15705065 0,18706188 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,15705065 0,18696506 ! RNA modification GO:0009451 40 31 0,000 0,15705065 0,18686833 ! regulation of muscle development GO:0048634 48 32 0,000 0,16168781 0,19228643 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,16168781 0,19218706 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,16168781 0,19208779 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,16168781 0,19198862 ! meiosis I GO:0007127 52 32 0,000 0,16168781 0,19188956 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,16168781 0,19179059 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,16168781 0,19169173 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,16168781 0,19159297 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,16168781 0,19149432 ! peripheral nervous system development GO:0007422 53 32 0,000 0,16168781 0,19139576 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,16168781 0,19129731 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,16168781 0,19119895 ! cytokine production GO:0001816 44 32 0,000 0,16168781 0,1911007 ! vesicle localization GO:0051648 47 32 0,000 0,16168781 0,19100255 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,16629973 0,19634978 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,16629973 0,19624904 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,16629973 0,1961484 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,16629973 0,19604786 ! sister chromatid segregation GO:0000819 46 33 0,000 0,16629973 0,19594743 ! actomyosin structure organization GO:0031032 43 33 0,000 0,16629973 0,19584709 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,16629973 0,19574687 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,16629973 0,19564674 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,16629973 0,19554672 ! positive regulation of cell development GO:0010720 54 33 0,000 0,16629973 0,19544679 ! lipid homeostasis GO:0055088 55 33 0,000 0,16629973 0,19534697 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,16629973 0,19524726 ! regulation of proteolysis GO:0030162 50 33 0,000 0,16629973 0,19514764 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,16629973 0,19504813 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,16629973 0,19494871 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,16629973 0,1948494 ! cytokinesis GO:0000910 52 33 0,000 0,16629973 0,19475019 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,16629973 0,19465108 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,17088654 0,19991813 ! mRNA catabolic process GO:0006402 48 34 0,000 0,17088654 0,19981649 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,17088654 0,19971496 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,17088654 0,19961353 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,17088654 0,1995122 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,17088654 0,19941098 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,17088654 0,19930986 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,17088654 0,19920884 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,17088654 0,19910792 ! female gamete generation GO:0007292 43 34 0,000 0,17088654 0,19900711 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,17088654 0,19890639 ! polyol metabolic process GO:0019751 44 34 0,000 0,17088654 0,19880578 ! aerobic respiration GO:0009060 47 34 0,000 0,17088654 0,19870528 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,17088654 0,19860487 ! embryonic organ development GO:0048568 45 34 0,000 0,17088654 0,19850456 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,17088654 0,19840436 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,17544837 0,20359801 ! Notch signaling pathway GO:0007219 56 35 0,000 0,17544837 0,20349534 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,17544837 0,20339277 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,17544837 0,2032903 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,17544837 0,20318794 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,17544837 0,20308568 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,17544837 0,20298353 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,17544837 0,20288148 ! pigment metabolic process GO:0042440 61 35 0,000 0,17544837 0,20277953 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,17544837 0,20267768 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,17544837 0,20257593 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,17998537 0,20771016 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,17998537 0,20760599 ! negative regulation of binding GO:0051100 58 36 0,000 0,17998537 0,20750193 ! organic ether metabolic process GO:0018904 46 36 0,000 0,17998537 0,20739797 ! tissue remodeling GO:0048771 62 36 0,000 0,17998537 0,20729411 ! neural tube development GO:0021915 50 36 0,000 0,17998537 0,20719036 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,17998537 0,20708672 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,17998537 0,20698317 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,17998537 0,20687973 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,18449766 0,21196034 ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,18449766 0,21185452 ! ion transmembrane transport GO:0034220 56 37 0,000 0,18449766 0,21174881 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,18449766 0,2116432 ! regulation of protein secretion GO:0050708 51 37 0,000 0,18449766 0,21153769 ! amino acid activation GO:0043038 52 37 0,000 0,18449766 0,21143229 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,18449766 0,211327 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,18898537 0,21635956 ! gliogenesis GO:0042063 71 38 0,000 0,18898537 0,21625192 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,18898537 0,21614439 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,18898537 0,21603696 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,18898537 0,21592964 ! phagocytosis GO:0006909 60 38 0,000 0,18898537 0,21582242 ! mesenchymal cell development GO:0014031 64 38 0,000 0,18898537 0,21571532 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,19344865 0,22070035 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,19344865 0,22059093 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,19344865 0,22048161 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,19344865 0,22037241 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,19344865 0,22026332 ! regulation of epithelial cell proliferation GO:0050678 71 39 0,000 0,19344865 0,22015433 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,19344865 0,22004545 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,19344865 0,21993668 ! chromatin remodeling GO:0006338 68 39 0,000 0,19344865 0,21982801 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,19344865 0,21971946 ! JNK cascade GO:0007254 54 39 0,000 0,19344865 0,21961101 ! developmental growth GO:0048589 62 39 0,000 0,19344865 0,21950266 ! cell growth GO:0016049 61 39 0,000 0,19344865 0,21939443 ! synapse organization GO:0050808 55 39 0,000 0,19344865 0,2192863 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,19788762 0,22420765 ! response to calcium ion GO:0051592 58 40 0,000 0,19788762 0,22409725 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,19788762 0,22398697 ! regulation of tube size GO:0035150 60 40 0,000 0,19788762 0,2238768 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,19788762 0,22376673 ! peptide metabolic process GO:0006518 56 40 0,000 0,19788762 0,22365677 ! inner ear development GO:0048839 57 40 0,000 0,19788762 0,22354692 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,19788762 0,22343717 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,19788762 0,22332754 ! double-strand break repair GO:0006302 67 40 0,000 0,19788762 0,22321801 ! B cell differentiation GO:0030183 62 40 0,000 0,19788762 0,22310859 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,19788762 0,22299928 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,20230241 0,22786266 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,20230241 0,22775112 ! endosome transport GO:0016197 71 41 0,000 0,20230241 0,2276397 ! striated muscle contraction GO:0006941 62 41 0,000 0,20230241 0,22752838 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,20230241 0,22741718 ! regulation of T cell differentiation GO:0045580 59 41 0,000 0,20230241 0,22730608 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,20230241 0,22719509 ! mitochondrial transport GO:0006839 60 42 0,000 0,20669315 0,23201281 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,20669315 0,23189964 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,20669315 0,23178657 ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,20669315 0,23167361 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,20669315 0,23156077 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,20669315 0,23144803 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,20669315 0,2313354 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,20669315 0,23122289 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 0,000 0,21105998 0,23599317 ! leukocyte migration GO:0050900 60 43 0,000 0,21105998 0,2358785 ! neuromuscular process GO:0050905 79 43 0,000 0,21105998 0,23576394 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,21105998 0,23564949 ! tRNA processing GO:0008033 49 43 0,000 0,21105998 0,23553516 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,21105998 0,23542093 ! vesicle organization GO:0016050 79 43 0,000 0,21105998 0,23530681 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,21105998 0,23519281 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,21540302 0,2399162 ! glycolysis GO:0006096 53 44 0,000 0,21540302 0,23980007 ! regulation of action potential GO:0001508 71 44 0,000 0,21540302 0,23968406 ! regulation of ion transport GO:0043269 57 44 0,000 0,21540302 0,23956816 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,21540302 0,23945237 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,21540302 0,23933669 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,21540302 0,23922112 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,21540302 0,23910567 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,21540302 0,23899033 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,21540302 0,23887509 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,21540302 0,23875997 ! RNA catabolic process GO:0006401 64 45 0,000 0,2197224 0,2434304 ! positive regulation of defense response GO:0031349 59 45 0,000 0,2197224 0,2433132 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,2197224 0,24319611 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,2197224 0,24307913 ! cell recognition GO:0008037 58 45 0,000 0,2197224 0,24296227 ! cell maturation GO:0048469 60 45 0,000 0,2197224 0,24284551 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,22401824 0,24747452 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,22401824 0,24735572 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,22401824 0,24723702 ! regulation of ossification GO:0030278 71 46 0,000 0,22401824 0,24711844 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,22401824 0,24699998 ! response to UV GO:0009411 75 46 0,000 0,22401824 0,24688163 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,22829068 0,25146962 ! viral infectious cycle GO:0019058 71 47 0,000 0,22829068 0,25134924 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,22829068 0,25122898 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,22829068 0,25110883 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,22829068 0,2509888 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,22829068 0,25086888 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,22829068 0,25074908 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,22829068 0,25062939 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,22829068 0,25050981 ! chloride transport GO:0006821 67 48 0,000 0,23253984 0,25505085 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,23253984 0,25492928 ! response to temperature stimulus GO:0009266 62 48 0,000 0,23253984 0,25480783 ! gastrulation GO:0007369 73 48 0,000 0,23253984 0,25468649 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,23253984 0,25456527 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,23253984 0,25444416 ! regulation of lymphocyte differentiation GO:0045619 69 48 0,000 0,23253984 0,25432317 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,23253984 0,2542023 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,23676585 0,25869902 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,23676585 0,25857619 ! sensory perception of smell GO:0007608 61 49 0,000 0,23676585 0,25845346 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,23676585 0,25833086 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,23676585 0,25820837 ! RNA elongation GO:0006354 62 49 0,000 0,23676585 0,25808599 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,23676585 0,25796374 ! germ cell development GO:0007281 68 49 0,000 0,23676585 0,25784159 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,23676585 0,25771957 ! cartilage development GO:0051216 70 49 0,000 0,23676585 0,25759766 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,24096882 0,26204647 ! membrane fusion GO:0006944 80 50 0,000 0,24096882 0,26192263 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,24096882 0,26179891 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,24096882 0,2616753 ! proton transport GO:0015992 75 50 0,000 0,24096882 0,26155181 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,24096882 0,26142844 ! positive regulation of secretion GO:0051047 71 51 0,000 0,24514889 0,26583803 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 0,000 0,24514889 0,26571275 ! hydrogen transport GO:0006818 77 51 0,000 0,24514889 0,26558759 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,24514889 0,26546255 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,24514889 0,26533763 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,24514889 0,26521282 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,24514889 0,26508813 ! adult behavior GO:0030534 80 51 0,000 0,24514889 0,26496356 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,24514889 0,2648391 ! transition metal ion transport GO:0000041 74 52 0,000 0,24930618 0,26920386 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,24930618 0,26907753 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,24930618 0,26895132 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,24930618 0,26882523 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,25344081 0,27315551 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,25344081 0,27302757 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,25344081 0,27289975 ! kidney development GO:0001822 90 53 0,000 0,25344081 0,27277205 ! single fertilization GO:0007338 59 53 0,000 0,25344081 0,27264447 ! amino acid transport GO:0006865 84 54 0,000 0,25755291 0,27693861 ! regulation of mitosis GO:0007088 84 54 0,000 0,25755291 0,2768092 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,25755291 0,27667991 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,25755291 0,27655074 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,25755291 0,27642169 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,25755291 0,27629276 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,25755291 0,27616396 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,25755291 0,27603527 ! exocytosis GO:0006887 74 55 0,000 0,26164258 0,28028782 ! mesoderm development GO:0007498 76 55 0,000 0,26164258 0,28015733 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,26164258 0,28002696 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,26164258 0,27989672 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,26570997 0,28411573 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,26570997 0,2839837 ! chromosome segregation GO:0007059 83 57 0,000 0,26975518 0,28817321 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,26975518 0,28803942 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,26975518 0,28790576 ! camera-type eye development GO:0043010 88 57 0,000 0,26975518 0,28777222 ! secondary metabolic process GO:0019748 84 57 0,000 0,26975518 0,28763881 ! developmental maturation GO:0021700 75 57 0,000 0,26975518 0,28750552 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,27777956 0,29592079 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,28175896 0,30002112 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,28175896 0,29988228 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,28175896 0,29974358 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,28175896 0,299605 ! regulation of heart contraction GO:0008016 91 60 0,000 0,28175896 0,29946655 ! fertilization GO:0009566 68 60 0,000 0,28175896 0,29932823 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,28571667 0,30339258 ! meiosis GO:0007126 96 61 0,000 0,28571667 0,30325258 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,28571667 0,3031127 ! urogenital system development GO:0001655 101 61 0,000 0,28571667 0,30297295 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,28571667 0,30283333 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,28571667 0,30269384 ! extracellular matrix organization GO:0030198 103 61 0,000 0,28571667 0,30255448 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,28571667 0,30241525 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,28571667 0,30227614 ! amine catabolic process GO:0009310 90 62 0,000 0,28965279 0,3062995 ! neurotransmitter transport GO:0006836 81 62 0,000 0,28965279 0,30615874 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,28965279 0,30601811 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,28965279 0,3058776 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,28965279 0,30573723 ! meiotic cell cycle GO:0051321 97 62 0,000 0,28965279 0,30559698 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,29356745 0,30958511 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 0,000 0,29356745 0,30944323 ! regulation of lipase activity GO:0060191 109 63 0,000 0,29356745 0,30930148 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,29746076 0,31325995 ! negative regulation of cell size GO:0045792 108 64 0,000 0,29746076 0,31311658 ! appendage morphogenesis GO:0035107 93 64 0,000 0,29746076 0,31297335 GO:0035108|limb morphogenesis, ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,29746076 0,31283024 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,29746076 0,31268727 ! hexose catabolic process GO:0019320 82 64 0,000 0,29746076 0,31254442 ! appendage development GO:0048736 94 65 0,000 0,30133283 0,31646827 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,30133283 0,31632383 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,30133283 0,31617952 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,30133283 0,31603534 ! defense response to bacterium GO:0042742 73 65 0,000 0,30133283 0,3158913 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,30133283 0,31574738 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,30133283 0,3156036 ! axon guidance GO:0007411 99 66 0,000 0,30518378 0,31949144 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,30518378 0,31934609 ! regulation of immune effector process GO:0002697 101 66 0,000 0,30518378 0,31920086 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,30901373 0,32305981 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,31282278 0,32689341 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,31282278 0,32674496 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,31282278 0,32659664 ! inorganic anion transport GO:0015698 93 68 0,000 0,31282278 0,32644846 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,31661106 0,3302519 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,31661106 0,33010219 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,31661106 0,32995262 ! response to metal ion GO:0010038 103 70 0,000 0,32037866 0,33372778 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,32037866 0,3335767 ! eye development GO:0001654 111 70 0,000 0,32037866 0,33342576 ! amine transport GO:0015837 101 70 0,000 0,32037866 0,33327496 ! positive regulation of phosphorylation GO:0042327 102 70 0,000 0,32037866 0,33312429 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,32037866 0,33297376 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,32412572 0,33671596 ! muscle cell differentiation GO:0042692 104 71 0,000 0,32412572 0,33656395 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,32412572 0,33641207 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,32412572 0,33626033 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,32412572 0,33610872 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 0,000 0,32785232 0,33981989 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,32785232 0,33966682 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,32785232 0,33951388 ! negative regulation of transport GO:0051051 116 73 0,000 0,33155859 0,34319746 ! regulation of blood pressure GO:0008217 107 73 0,000 0,33155859 0,34304308 ! tube morphogenesis GO:0035239 118 73 0,000 0,33155859 0,34288883 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,33155859 0,34273472 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,33155859 0,34258076 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,33524464 0,3462338 ! digestion GO:0007586 97 74 0,000 0,33524464 0,3460784 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,33524464 0,34592313 ! response to inorganic substance GO:0010035 115 75 0,000 0,33891057 0,34954902 ! negative regulation of growth GO:0045926 123 75 0,000 0,33891057 0,34939234 ! response to nutrient GO:0007584 104 75 0,000 0,33891057 0,3492358 ! regulation of ligase activity GO:0051340 114 75 0,000 0,33891057 0,3490794 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,33891057 0,34892315 ! amine biosynthetic process GO:0009309 97 76 0,000 0,34255649 0,35251898 ! tRNA metabolic process GO:0006399 95 76 0,000 0,34255649 0,35236133 ! response to unfolded protein GO:0006986 99 76 0,000 0,34255649 0,35220381 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,34618252 0,35577292 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,34618252 0,35561402 ! protein ubiquitination GO:0016567 125 77 0,000 0,34618252 0,35545526 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,34618252 0,35529665 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,34978875 0,3588377 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,34978875 0,35867772 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,34978875 0,35851788 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,3533753 0,3620326 ! cellular respiration GO:0045333 107 79 0,000 0,3533753 0,36187141 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,3533753 0,36171036 ! regulation of lyase activity GO:0051339 133 79 0,000 0,3533753 0,36154946 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,3533753 0,3613887 ! chromatin assembly GO:0031497 102 80 0,000 0,35694227 0,36487432 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,35694227 0,36471222 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,35694227 0,36455027 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,35694227 0,36438846 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,36048976 0,3678467 ! response to protein stimulus GO:0051789 111 81 0,000 0,36048976 0,36768357 ! regulation of neurological system process GO:0031644 122 81 0,000 0,36048976 0,36752059 ! vitamin metabolic process GO:0006766 103 81 0,000 0,36048976 0,36735776 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,36048976 0,36719506 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 0,000 0,36401789 0,37062468 GO:0060348|bone development, ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,36752676 0,37403166 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,36752676 0,37386623 ! regulation of cell adhesion GO:0030155 159 83 0,000 0,36752676 0,37370095 ! regulation of defense response GO:0031347 117 84 0,000 0,37101647 0,37708258 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,37101647 0,37691602 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,37101647 0,37674961 ! sterol metabolic process GO:0016125 120 84 0,000 0,37101647 0,37658335 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,37448712 0,37993841 ! rRNA metabolic process GO:0016072 107 85 0,000 0,37448712 0,37977089 GO:0006364|rRNA processing, ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,37448712 0,37960352 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,37793882 0,38293361 ! interphase of mitotic cell cycle GO:0051329 156 86 0,000 0,37793882 0,38276499 ! nucleosome organization GO:0034728 114 87 0,000 0,38137167 0,38607167 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,38137167 0,38590182 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,38137167 0,38573212 ! female pregnancy GO:0007565 130 87 0,000 0,38137167 0,38556257 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,38478577 0,38884327 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,38478577 0,3886725 ! interphase GO:0051325 159 88 0,000 0,38478577 0,38850188 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,38478577 0,38833141 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,38818123 0,39158633 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,38818123 0,39141466 ! regulation of T cell activation GO:0050863 128 89 0,000 0,38818123 0,39124313 ! hormone metabolic process GO:0042445 121 90 0,000 0,39155814 0,39447382 ! ATP metabolic process GO:0046034 137 91 0,000 0,39491661 0,3976831 ! response to virus GO:0009615 122 91 0,000 0,39491661 0,39750906 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,39825672 0,40069574 ! cell fate commitment GO:0045165 141 92 0,000 0,39825672 0,40052054 ! DNA recombination GO:0006310 146 92 0,000 0,39825672 0,40034548 ! sulfur metabolic process GO:0006790 118 92 0,000 0,39825672 0,40017058 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,4015786 0,40333221 ! electron transport chain GO:0022900 123 94 0,000 0,40488232 0,40647287 ! angiogenesis GO:0001525 149 95 0,000 0,40816799 0,40959266 ! carboxylic acid transport GO:0046942 147 95 0,000 0,40816799 0,40941404 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,41143572 0,41251183 ! response to light stimulus GO:0009416 153 96 0,000 0,41143572 0,41233209 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,41468558 0,41540803 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! extracellular structure organization GO:0043062 156 99 0,000 0,42113213 0,42168215 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,42432901 0,42469831 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,42432901 0,42451358 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,42432901 0,42432901