pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/565-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of lipid kinase activity GO:0043550 13 7 3,000 3,974E-09 9,561E-06 ! negative regulation of growth GO:0045926 155 84 6,000 1,321E-08 1,589E-05 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 1,475E-08 1,183E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 2,27E-08 1,366E-05 GO:0045936|negative regulation of phosphate metabolic process, ! interphase of mitotic cell cycle GO:0051329 209 95 6,000 3,129E-08 1,506E-05 ! interphase GO:0051325 213 98 6,000 3,886E-08 1,558E-05 ! negative regulation of cell growth GO:0030308 132 67 5,000 9,754E-08 3,352E-05 ! negative regulation of cell size GO:0045792 134 69 5,000 1,165E-07 3,505E-05 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 3,177E-07 8,493E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 4,011E-07 9,651E-05 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 3,000 4,268E-07 9,335E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 4,489E-07 9E-05 ! positive regulation of inflammatory response GO:0050729 35 21 3,000 6,557E-07 1,214E-04 ! nuclear migration GO:0007097 12 6 2,000 7,053E-07 1,212E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 7,053E-07 1,131E-04 GO:0031272|regulation of pseudopodium assembly, ! macrophage differentiation GO:0030225 11 7 2,000 1,231E-06 1,851E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 1,231E-06 1,743E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 1,332E-06 1,781E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,893E-06 2,398E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,965E-06 2,364E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 2,941E-06 3,369E-04 ! keratinocyte proliferation GO:0043616 14 9 2,000 2,941E-06 3,216E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 2,993E-06 3,131E-04 ! negative regulation of kinase activity GO:0033673 131 68 4,000 3,222E-06 3,23E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 4,191E-06 4,033E-04 ! negative regulation of transferase activity GO:0051348 140 72 4,000 4,279E-06 3,96E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 5,748E-06 5,123E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 5,748E-06 4,94E-04 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 19 11 2,000 5,748E-06 4,769E-04 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 7,646E-06 6,132E-04 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 30 12 2,000 7,646E-06 5,934E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 1,259E-05 9,466E-04 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 1,278E-05 9,32E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,57E-05 1,111E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 1,755E-05 1,207E-03 ! positive regulation of defense response GO:0031349 76 47 3,000 1,829E-05 1,222E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,928E-05 1,253E-03 ! regulation of inflammatory response GO:0050727 75 48 3,000 1,99E-05 1,26E-03 ! cell cycle arrest GO:0007050 213 100 4,000 2,14E-05 1,32E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 2,335E-05 1,404E-03 ! microspike assembly GO:0030035 36 17 2,000 2,335E-05 1,37E-03 ! response to UV GO:0009411 104 53 3,000 2,957E-05 1,694E-03 ! G1 phase GO:0051318 40 19 2,000 3,311E-05 1,853E-03 ! regulation of glucose import GO:0046324 29 20 2,000 3,886E-05 2,125E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 4,523E-05 2,418E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 4,523E-05 2,366E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! establishment of organelle localization GO:0051656 109 59 3,000 4,526E-05 2,317E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 4,837E-05 2,425E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 5,225E-05 2,565E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 5,864E-05 2,822E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 5,994E-05 2,828E-03 ! regulation of DNA recombination GO:0000018 48 23 2,000 5,994E-05 2,773E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 6,631E-05 3,01E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 6,834E-05 3,045E-03 ! regulation of behavior GO:0050795 43 24 2,000 6,834E-05 2,989E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 6,834E-05 2,936E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 7,469E-05 3,153E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 8,736E-05 3,624E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 9,804E-05 3,998E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 9,804E-05 3,932E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 1,084E-04 4,277E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,084E-04 4,208E-03 ! anagen GO:0042640 6 5 1,000 1,084E-04 4,141E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,084E-04 4,077E-03 ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 1,000 1,084E-04 4,014E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,084E-04 3,953E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,084E-04 3,894E-03 ! negative regulation of T cell mediated immunity GO:0002710 12 5 1,000 1,084E-04 3,837E-03 GO:0002707|negative regulation of lymphocyte mediated immunity, ! decidualization GO:0046697 11 5 1,000 1,084E-04 3,781E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 1,095E-04 3,765E-03 ! organelle localization GO:0051640 136 74 3,000 1,102E-04 3,733E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,219E-04 4,073E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,219E-04 4,017E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 1,42E-04 4,618E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 1,565E-04 5,019E-03 GO:0045937|positive regulation of phosphate metabolic process, ! male meiosis GO:0007140 7 6 1,000 1,623E-04 5,138E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 1,623E-04 5,072E-03 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 1,623E-04 5,007E-03 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 1,000 1,623E-04 4,943E-03 ! hair follicle maturation GO:0048820 7 6 1,000 1,623E-04 4,881E-03 ! negative regulation of multicellular organism growth GO:0040015 8 6 1,000 1,623E-04 4,821E-03 ! G2 phase GO:0051319 16 6 1,000 1,623E-04 4,762E-03 GO:0000085|G2 phase of mitotic cell cycle, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,623E-04 4,705E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 1,623E-04 4,649E-03 ! maternal placenta development GO:0001893 12 6 1,000 1,623E-04 4,594E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 1,643E-04 4,596E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,803E-04 4,985E-03 GO:0060326|cell chemotaxis, ! calcium-mediated signaling GO:0019722 62 35 2,000 2,152E-04 5,884E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,267E-04 6,13E-03 ! neuron adhesion GO:0007158 12 7 1,000 2,267E-04 6,062E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,267E-04 5,995E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 2,267E-04 5,93E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,267E-04 5,866E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,267E-04 5,804E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,267E-04 5,743E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,267E-04 5,683E-03 ! lymph node development GO:0048535 10 7 1,000 2,267E-04 5,624E-03 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 1,000 2,267E-04 5,567E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 2,542E-04 6,179E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,542E-04 6,117E-03 ! regulation of defense response GO:0031347 149 92 3,000 2,555E-04 6,088E-03 ! mammary gland development GO:0030879 86 39 2,000 2,976E-04 7,02E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 3,017E-04 7,047E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,017E-04 6,979E-03 ! ER overload response GO:0006983 12 8 1,000 3,017E-04 6,912E-03 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 3,017E-04 6,847E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 3,017E-04 6,783E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 3,017E-04 6,72E-03 ! regulation of fat cell differentiation GO:0045598 15 8 1,000 3,017E-04 6,659E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 3,017E-04 6,598E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 3,017E-04 6,539E-03 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 3,129E-04 6,722E-03 ! cytokinesis GO:0000910 72 40 2,000 3,21E-04 6,834E-03 ! gliogenesis GO:0042063 88 41 2,000 3,455E-04 7,291E-03 ! T cell differentiation GO:0030217 81 41 2,000 3,455E-04 7,228E-03 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 3,712E-04 7,698E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 3,87E-04 7,959E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,87E-04 7,891E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,87E-04 7,825E-03 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 1,000 3,87E-04 7,76E-03 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage differentiation GO:0045649 15 9 1,000 3,87E-04 7,696E-03 ! leukocyte migration GO:0050900 68 45 2,000 4,555E-04 8,982E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,827E-04 9,443E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,827E-04 9,366E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 4,827E-04 9,291E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 4,827E-04 9,218E-03 ! negative regulation of immune effector process GO:0002698 20 10 1,000 4,827E-04 9,145E-03 ! localization within membrane GO:0051668 20 10 1,000 4,827E-04 9,074E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 4,861E-04 9,066E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 5,512E-04 0,01020092 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 5,857E-04 0,01075736 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,887E-04 0,01073075 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,887E-04 0,01065007 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,887E-04 0,01057059 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 1,000 5,887E-04 0,01049229 ! regulation of synapse organization GO:0050807 17 11 1,000 5,887E-04 0,01041514 ! regulation of cell projection organization GO:0031344 121 50 2,000 6,216E-04 0,01091653 ! histone modification GO:0016570 91 50 2,000 6,216E-04 0,01083743 ! regulation of muscle contraction GO:0006937 81 52 2,000 6,975E-04 0,01207368 ! covalent chromatin modification GO:0016569 101 52 2,000 6,975E-04 0,01198744 ! cartilage development GO:0051216 90 52 2,000 6,975E-04 0,01190242 ! regulation of B cell proliferation GO:0030888 20 12 1,000 7,049E-04 0,01194417 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 7,049E-04 0,01186064 ! entry into host cell GO:0030260 32 12 1,000 7,049E-04 0,01177827 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 7,049E-04 0,01169705 ! peptidyl-lysine modification GO:0018205 21 12 1,000 7,049E-04 0,01161693 ! regulation of synapse structure and activity GO:0050803 18 12 1,000 7,049E-04 0,0115379 ! activation of phospholipase C activity GO:0007202 103 54 2,000 7,791E-04 0,01266588 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 8,221E-04 0,01327478 ! response to X-ray GO:0010165 25 13 1,000 8,313E-04 0,01333407 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 8,313E-04 0,01324576 ! regulation of cellular pH GO:0030641 22 13 1,000 8,313E-04 0,01315862 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 8,313E-04 0,01307262 ! positive regulation of cell migration GO:0030335 126 57 2,000 9,125E-04 0,01425609 ! lipid modification GO:0030258 97 57 2,000 9,125E-04 0,01416411 ! regulation of phospholipase activity GO:0010517 106 57 2,000 9,125E-04 0,01407332 ! positive regulation of lipase activity GO:0060193 108 58 2,000 9,599E-04 0,01471106 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 9,678E-04 0,01473679 ! embryo implantation GO:0007566 30 14 1,000 9,678E-04 0,01464411 ! response to gamma radiation GO:0010332 28 14 1,000 9,678E-04 0,01455258 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 9,678E-04 0,0144622 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 9,678E-04 0,01437292 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 1,009E-03 0,01489284 ! regulation of heart contraction GO:0008016 110 60 2,000 1,06E-03 0,01554374 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,112E-03 0,0162097 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 1,112E-03 0,01611205 ! heterophilic cell adhesion GO:0007157 39 15 1,000 1,114E-03 0,01605281 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,114E-03 0,01595726 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,114E-03 0,01586284 ! regulation of vasodilation GO:0042312 26 15 1,000 1,114E-03 0,01576953 ! regulation of T cell mediated immunity GO:0002709 33 15 1,000 1,114E-03 0,01567731 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,114E-03 0,01558616 ! regulation of homeostatic process GO:0032844 134 62 2,000 1,165E-03 0,01620729 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,271E-03 0,01756994 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 1,000 1,271E-03 0,01746954 ! negative regulation of immune response GO:0050777 35 16 1,000 1,271E-03 0,01737028 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,271E-03 0,01727214 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,278E-03 0,01727 ! cell projection assembly GO:0030031 120 66 2,000 1,397E-03 0,01877161 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,437E-03 0,01920723 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,437E-03 0,01910111 ! homeostasis of number of cells GO:0048872 114 67 2,000 1,459E-03 0,01928131 ! regulation of lipase activity GO:0060191 130 68 2,000 1,522E-03 0,02001296 ! cell cycle checkpoint GO:0000075 137 69 2,000 1,588E-03 0,02075911 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,613E-03 0,02097868 ! memory GO:0007613 31 18 1,000 1,613E-03 0,0208659 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 1,613E-03 0,02075431 GO:0050886|endocrine process, ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,613E-03 0,02064392 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 1,613E-03 0,02053469 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 1,794E-03 0,02271993 ! lipid phosphorylation GO:0046834 35 19 1,000 1,799E-03 0,02266114 ! pigmentation during development GO:0048066 41 19 1,000 1,799E-03 0,02254312 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 1,799E-03 0,02242631 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 1,799E-03 0,02231071 ! meiosis GO:0007126 121 74 2,000 1,941E-03 0,02394658 GO:0051327|M phase of meiotic cell cycle, ! protein amino acid acetylation GO:0006473 39 20 1,000 1,995E-03 0,02448372 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,995E-03 0,02435944 ! cellular response to starvation GO:0009267 33 20 1,000 1,995E-03 0,02423641 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 1,995E-03 0,02411462 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 1,995E-03 0,02399404 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 1,995E-03 0,02387467 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,995E-03 0,02375648 ! meiotic cell cycle GO:0051321 122 75 2,000 2,017E-03 0,02390401 ! lymphocyte differentiation GO:0030098 167 75 2,000 2,017E-03 0,02378683 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 2,174E-03 0,02552013 ! regulation of cell killing GO:0031341 42 21 1,000 2,2E-03 0,02569171 ! cell aging GO:0007569 44 21 1,000 2,2E-03 0,02556759 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 2,2E-03 0,02544467 ! regulation of vasoconstriction GO:0019229 39 21 1,000 2,2E-03 0,02532292 ! vitamin A metabolic process GO:0006776 33 21 1,000 2,2E-03 0,02520234 ! protein oligomerization GO:0051259 139 78 2,000 2,256E-03 0,02572457 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 2,414E-03 0,02740174 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 2,414E-03 0,0272731 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 2,414E-03 0,02714565 ! renal system process GO:0003014 41 22 1,000 2,414E-03 0,0270194 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,414E-03 0,02689431 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 2,414E-03 0,02677037 ! protein import into nucleus GO:0006606 158 80 2,000 2,425E-03 0,02676135 ! T cell activation GO:0042110 168 81 2,000 2,512E-03 0,02759762 ! nuclear import GO:0051170 161 81 2,000 2,512E-03 0,02747217 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 2,601E-03 0,02831856 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,639E-03 0,0285977 ! leukocyte adhesion GO:0007159 50 23 1,000 2,639E-03 0,02846946 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 2,639E-03 0,02834236 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,639E-03 0,0282164 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 2,639E-03 0,02809155 ! fatty acid transport GO:0015908 44 23 1,000 2,639E-03 0,0279678 ! negative regulation of transport GO:0051051 153 84 2,000 2,785E-03 0,02939228 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,872E-03 0,03017859 ! protein tetramerization GO:0051262 52 24 1,000 2,872E-03 0,03004738 ! positive regulation of cell activation GO:0050867 145 85 2,000 2,88E-03 0,0300001 GO:0002696|positive regulation of leukocyte activation, ! protein localization in nucleus GO:0034504 176 87 2,000 3,076E-03 0,03190291 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 3,115E-03 0,03217011 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 3,115E-03 0,03203263 ! negative regulation of DNA replication GO:0008156 42 25 1,000 3,115E-03 0,03189632 ! response to starvation GO:0042594 42 25 1,000 3,115E-03 0,03176117 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 3,115E-03 0,03162716 ! negative regulation of cell development GO:0010721 73 25 1,000 3,115E-03 0,03149427 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 3,115E-03 0,03136249 ! somitogenesis GO:0001756 43 25 1,000 3,115E-03 0,03123182 ! cellular response to nutrient levels GO:0031669 41 25 1,000 3,115E-03 0,03110223 ! positive regulation of protein modification process GO:0031401 136 88 2,000 3,177E-03 0,03158846 ! gland development GO:0048732 206 88 2,000 3,177E-03 0,03145847 ! initiation of viral infection GO:0019059 57 26 1,000 3,368E-03 0,03320802 ! molting cycle process GO:0022404 50 26 1,000 3,368E-03 0,03307248 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,368E-03 0,03293804 ! positive regulation of nuclear division GO:0051785 40 26 1,000 3,368E-03 0,03280468 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 3,368E-03 0,03267241 ! ossification GO:0001503 188 90 2,000 3,385E-03 0,03271022 ! bone development GO:0060348 189 91 2,000 3,492E-03 0,03360964 ! protein amino acid acylation GO:0043543 55 27 1,000 3,629E-03 0,03478927 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,629E-03 0,03465121 ! base-excision repair GO:0006284 41 27 1,000 3,629E-03 0,03451425 ! regulation of chromosome organization GO:0033044 42 27 1,000 3,629E-03 0,03437837 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 3,629E-03 0,03424355 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 3,713E-03 0,03489211 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,9E-03 0,0365118 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 3,9E-03 0,03637028 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 3,9E-03 0,03622985 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,9E-03 0,03609051 ! lipid oxidation GO:0034440 43 28 1,000 3,9E-03 0,03595223 GO:0019395|fatty acid oxidation, ! regulation of pH GO:0006885 43 29 1,000 4,18E-03 0,03838505 ! cell junction assembly GO:0034329 78 30 1,000 4,469E-03 0,04088218 ! ensheathment of neurons GO:0007272 57 30 1,000 4,469E-03 0,04072733 GO:0008366|axon ensheathment, ! regulation of B cell activation GO:0050864 50 30 1,000 4,469E-03 0,04057364 ! erythrocyte differentiation GO:0030218 55 31 1,000 4,767E-03 0,04311568 ! fatty acid catabolic process GO:0009062 48 31 1,000 4,767E-03 0,0429542 ! spindle organization GO:0007051 46 32 1,000 5,074E-03 0,04554854 ! response to ionizing radiation GO:0010212 65 32 1,000 5,074E-03 0,04537921 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 5,074E-03 0,04521114 ! DNA damage checkpoint GO:0000077 71 33 1,000 5,389E-03 0,04784714 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 5,389E-03 0,04767124 ! glial cell differentiation GO:0010001 63 34 1,000 5,714E-03 0,05035652 ! placenta development GO:0001890 53 34 1,000 5,714E-03 0,05017273 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,714E-03 0,04999029 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 6,047E-03 0,05271421 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 6,047E-03 0,0525239 ! neural tube formation GO:0001841 67 35 1,000 6,047E-03 0,05233497 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 6,389E-03 0,05509608 ! cell junction organization GO:0034330 86 36 1,000 6,389E-03 0,05489931 ! DNA integrity checkpoint GO:0031570 75 36 1,000 6,389E-03 0,05470394 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 6,389E-03 0,05450995 ! meiosis I GO:0007127 65 37 1,000 6,74E-03 0,05729767 ! sister chromatid segregation GO:0000819 58 37 1,000 6,74E-03 0,05709591 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,74E-03 0,05689558 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 7,099E-03 0,05971775 ! erythrocyte homeostasis GO:0034101 64 38 1,000 7,099E-03 0,05950968 ! isoprenoid metabolic process GO:0006720 66 38 1,000 7,099E-03 0,05930305 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 7,099E-03 0,05909785 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 7,099E-03 0,05889406 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! segmentation GO:0035282 67 39 1,000 7,466E-03 0,06173119 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 7,466E-03 0,06151978 ! regulation of action potential in neuron GO:0019228 73 39 1,000 7,466E-03 0,06130982 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 8,227E-03 0,06732513 ! regulation of T cell differentiation GO:0045580 70 41 1,000 8,227E-03 0,06709691 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 8,227E-03 0,06687023 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 8,62E-03 0,069827 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 1,000 8,62E-03 0,06959268 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 1,000 8,62E-03 0,06935993 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 8,62E-03 0,06912873 ! glucose transport GO:0015758 65 43 1,000 9,021E-03 0,0721048 ! striated muscle cell differentiation GO:0051146 82 43 1,000 9,021E-03 0,07186604 ! neural tube development GO:0021915 77 43 1,000 9,021E-03 0,07162886 ! hexose transport GO:0008645 67 44 1,000 9,43E-03 0,07463232 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 1,000 9,43E-03 0,07438762 ! B cell differentiation GO:0030183 107 44 1,000 9,43E-03 0,07414453 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 9,43E-03 0,07390301 ! developmental growth GO:0048589 82 44 1,000 9,43E-03 0,07366307 ! cell growth GO:0016049 84 45 1,000 9,847E-03 0,07667483 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,01027277 0,07972999 ! pigmentation GO:0043473 100 46 1,000 0,01027277 0,07947362 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01070632 0,08256221 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01070632 0,08229843 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,01070632 0,08203634 ! mitochondrial transport GO:0006839 82 48 1,000 0,01114785 0,08514834 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,01114785 0,08487888 ! activation of caspase activity GO:0006919 84 48 1,000 0,01114785 0,08461112 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01114785 0,08434505 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01114785 0,08408065 ! regulation of action potential GO:0001508 95 49 1,000 0,0115973 0,08719722 ! regulation of ossification GO:0030278 117 50 1,000 0,01205462 0,09035335 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01205462 0,09007275 ! positive regulation of binding GO:0051099 78 51 1,000 0,01251976 0,09325862 ! viral infectious cycle GO:0019058 99 51 1,000 0,01251976 0,09297079 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,01251976 0,09268472 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01251976 0,09240041 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,01251976 0,09211784 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01347324 0,09883112 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,0144573 0,10572723 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 1,000 0,0144573 0,10540684 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,0144573 0,10508839 ! RNA elongation GO:0006354 79 55 1,000 0,0144573 0,10477186 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,01496066 0,10809413 ! regulation of DNA replication GO:0006275 101 56 1,000 0,01496066 0,10777049 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,01496066 0,10744879 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,0154715 0,110787 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01598977 0,11415843 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01649312 0,11740371 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01649312 0,11705739 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01649312 0,1167131 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01649312 0,11637083 ! neuron fate determination GO:0048664 7 5 0,000 0,01649312 0,11603057 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01649312 0,11569229 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01649312 0,11535597 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01649312 0,11502161 ! polyol transport GO:0015791 12 5 0,000 0,01649312 0,11468917 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01649312 0,11435866 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01649312 0,11403004 ! response to superoxide GO:0000303 10 5 0,000 0,01649312 0,11370331 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01649312 0,11337844 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01649312 0,11305543 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01649312 0,11273425 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01649312 0,11241488 ! female meiosis GO:0007143 7 5 0,000 0,01649312 0,11209733 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01649312 0,11178156 ! cobalt ion transport GO:0006824 11 5 0,000 0,01649312 0,11146757 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01649312 0,11115533 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01649312 0,11084484 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01649312 0,11053608 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01649312 0,11022904 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01649312 0,1099237 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01649312 0,10962004 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01649312 0,10931806 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01649312 0,10901773 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01649312 0,10871905 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01649312 0,10842201 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01649312 0,10812658 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01649312 0,10783276 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01649312 0,10754053 ! negative chemotaxis GO:0050919 14 5 0,000 0,01649312 0,10724988 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01649312 0,10696079 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01649312 0,10667326 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01649312 0,10638728 ! behavioral response to pain GO:0048266 9 5 0,000 0,01649312 0,10610282 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01649312 0,10581988 ! Notch receptor processing GO:0007220 8 5 0,000 0,01649312 0,10553844 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01649312 0,1052585 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01649312 0,10498004 ! micturition GO:0060073 9 5 0,000 0,01649312 0,10470305 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01649312 0,10442751 ! copulation GO:0007620 9 5 0,000 0,01649312 0,10415342 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01649312 0,10388077 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01649312 0,10360954 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01649312 0,10333972 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01649312 0,10307131 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01649312 0,10280429 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01649312 0,10253864 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01649312 0,10227437 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01649312 0,10201145 ! grooming behavior GO:0007625 6 5 0,000 0,01649312 0,10174988 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01649312 0,10148965 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01649312 0,10123075 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01649312 0,10097317 ! response to protozoan GO:0001562 10 5 0,000 0,01649312 0,10071689 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,01649312 0,10046191 ! lymph vessel development GO:0001945 10 5 0,000 0,01649312 0,10020822 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01649312 0,0999558 ! endochondral ossification GO:0001958 16 5 0,000 0,01649312 0,09970466 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01649312 0,09945477 ! parathyroid gland development GO:0060017 13 5 0,000 0,01649312 0,09920614 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01649312 0,09895874 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01649312 0,09871257 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01649312 0,09846763 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01649312 0,0982239 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01649312 0,09798137 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01649312 0,09774004 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01649312 0,09749989 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01649312 0,09726092 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01649312 0,09702312 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01649312 0,09678647 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01649312 0,09655098 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01649312 0,09631664 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01649312 0,09608342 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01649312 0,09585134 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01649312 0,09562037 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01649312 0,09539052 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01649312 0,09516176 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01649312 0,0949341 ! histidine catabolic process GO:0006548 6 5 0,000 0,01649312 0,09470753 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01649312 0,09448203 ! microvillus organization GO:0032528 7 5 0,000 0,01649312 0,09425761 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01649312 0,09403425 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01649312 0,09381195 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01649312 0,09359069 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01649312 0,09337048 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01649312 0,0931513 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01649312 0,09293315 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01649312 0,09271601 ! polyol catabolic process GO:0046174 7 5 0,000 0,01649312 0,09249989 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01649312 0,09228478 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01649312 0,09207066 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01649312 0,09185753 ! muscle cell migration GO:0014812 8 5 0,000 0,01649312 0,09164539 ! mitochondrial fission GO:0000266 8 5 0,000 0,01649312 0,09143423 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01649312 0,09122403 ! mRNA transcription GO:0009299 9 5 0,000 0,01649312 0,0910148 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01649312 0,09080653 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01649312 0,09059921 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01649312 0,09039283 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01649312 0,0901874 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01649312 0,08998289 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01649312 0,08977931 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01649312 0,08957665 ! response to food GO:0032094 6 5 0,000 0,01649312 0,0893749 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01649312 0,08917405 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01649312 0,08897411 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01649312 0,08877507 GO:0032881|regulation of polysaccharide metabolic process, ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01649312 0,08857691 ! forebrain neuron development GO:0021884 13 5 0,000 0,01649312 0,08837963 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01649312 0,08818323 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01649312 0,0879877 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01649312 0,08779304 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01649312 0,08759924 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01649312 0,08740629 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01649312 0,08721419 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01649312 0,08702293 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01649312 0,0868325 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01649312 0,08664291 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01649312 0,08645415 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01649312 0,08626621 ! basic amino acid transport GO:0015802 11 5 0,000 0,01649312 0,08607908 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01649312 0,08589276 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01649312 0,08570724 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01649312 0,08552253 ! depyrimidination GO:0045008 10 5 0,000 0,01649312 0,08533861 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01649312 0,08515548 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01649312 0,08497314 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01649312 0,08479157 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01649312 0,08461078 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01649312 0,08443075 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01649312 0,0842515 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01649312 0,084073 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01649312 0,08389525 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01649312 0,08371826 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01649312 0,08354201 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01649312 0,0833665 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01649312 0,08319173 ! response to arsenic GO:0046685 10 5 0,000 0,01649312 0,08301769 ! mast cell degranulation GO:0043303 7 5 0,000 0,01649312 0,08284437 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01649312 0,08267178 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01649312 0,08249991 ! response to cadmium ion GO:0046686 7 5 0,000 0,01649312 0,08232874 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01649312 0,08215829 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01649312 0,08198854 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01649312 0,08181949 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01649312 0,08165114 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01649312 0,08148348 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01649312 0,0813165 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01649312 0,08115021 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01649312 0,0809846 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01649312 0,08081966 ! neural tube patterning GO:0021532 7 5 0,000 0,01649312 0,0806554 ! embryonic cleavage GO:0040016 6 5 0,000 0,01649312 0,08049179 ! peroxisome fission GO:0016559 5 5 0,000 0,01649312 0,08032886 ! histone demethylation GO:0016577 10 5 0,000 0,01649312 0,08016657 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01649312 0,08000495 ! mitotic recombination GO:0006312 9 5 0,000 0,01649312 0,07984397 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01649312 0,07968364 ! metaphase plate congression GO:0051310 7 5 0,000 0,01649312 0,07952396 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01649312 0,07936491 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01649312 0,0792065 ! enteric nervous system development GO:0048484 8 5 0,000 0,01649312 0,07904871 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01649312 0,07889156 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01649312 0,07873503 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01649312 0,07857912 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01649312 0,07842382 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01649312 0,07826914 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01649312 0,07811507 ! plasminogen activation GO:0031639 5 5 0,000 0,01649312 0,0779616 ! B cell homeostasis GO:0001782 13 5 0,000 0,01649312 0,07780873 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01649312 0,07765647 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01649312 0,07750479 ! metaphase GO:0051323 8 5 0,000 0,01649312 0,07735371 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01649312 0,07720322 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01649312 0,07705331 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01649312 0,07690398 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01649312 0,07675523 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01649312 0,07660705 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01649312 0,07645945 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01649312 0,07631241 ! response to redox state GO:0051775 5 5 0,000 0,01649312 0,07616594 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01649312 0,07602003 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01649312 0,07587467 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01649312 0,07572987 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01649312 0,07558563 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01649312 0,07544193 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01649312 0,07529877 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01649312 0,07515616 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01649312 0,07501409 ! striatum development GO:0021756 9 5 0,000 0,01649312 0,07487256 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01649312 0,07473155 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01649312 0,07459108 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01649312 0,07445113 ! glial cell migration GO:0008347 11 5 0,000 0,01649312 0,07431171 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01649312 0,07417281 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01649312 0,07403443 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01649312 0,07389656 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01649312 0,07375921 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01649312 0,07362236 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01649312 0,07348603 ! neuroprotection GO:0043526 6 5 0,000 0,01649312 0,07335019 ! neural plate development GO:0001840 8 5 0,000 0,01649312 0,07321486 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01649312 0,07308003 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01649312 0,07294569 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01649312 0,07281184 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01649312 0,07267849 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01649312 0,07254562 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01649312 0,07241324 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01649312 0,07228134 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01649312 0,07214992 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01649312 0,07201897 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01649312 0,0718885 ! spindle assembly GO:0051225 6 5 0,000 0,01649312 0,07175851 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01649312 0,07162898 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01649312 0,07149992 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01649312 0,07137132 ! drug metabolic process GO:0017144 6 5 0,000 0,01649312 0,07124319 ! stem cell division GO:0017145 11 5 0,000 0,01649312 0,07111551 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01649312 0,07098829 ! organ regeneration GO:0031100 7 5 0,000 0,01649312 0,07086153 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01649312 0,07073521 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01649312 0,07060935 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01649312 0,07048393 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,01651541 0,07045405 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,01704838 0,07259893 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,01704838 0,07247066 ! kidney development GO:0001822 122 60 1,000 0,01704838 0,07234285 ! viral reproductive process GO:0022415 126 62 1,000 0,01813605 0,07682276 ! regulation of mitosis GO:0007088 105 63 1,000 0,01869065 0,07903286 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01869065 0,07889421 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,01925236 0,08112289 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01975929 0,08311336 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01975929 0,08296831 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01975929 0,08282377 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01975929 0,08267972 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01975929 0,08253618 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01975929 0,08239314 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01975929 0,08225059 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01975929 0,08210853 ! sleep GO:0030431 13 6 0,000 0,01975929 0,08196697 ! response to oxygen radical GO:0000305 11 6 0,000 0,01975929 0,08182589 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01975929 0,08168529 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01975929 0,08154518 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01975929 0,08140555 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01975929 0,0812664 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01975929 0,08112772 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01975929 0,08098951 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01975929 0,08085177 ! forebrain regionalization GO:0021871 8 6 0,000 0,01975929 0,0807145 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01975929 0,0805777 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01975929 0,08044136 ! response to zinc ion GO:0010043 9 6 0,000 0,01975929 0,08030548 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01975929 0,08017005 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01975929 0,08003509 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01975929 0,07990057 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01975929 0,07976651 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01975929 0,0796329 ! malate metabolic process GO:0006108 11 6 0,000 0,01975929 0,07949974 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01975929 0,07936701 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01975929 0,07923474 ! protein refolding GO:0042026 15 6 0,000 0,01975929 0,0791029 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01975929 0,0789715 ! opsonization GO:0008228 8 6 0,000 0,01975929 0,07884053 ! mating behavior GO:0007617 7 6 0,000 0,01975929 0,07871 ! neuron remodeling GO:0016322 15 6 0,000 0,01975929 0,0785799 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01975929 0,07845023 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01975929 0,07832099 ! equilibrioception GO:0050957 14 6 0,000 0,01975929 0,07819217 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01975929 0,07806378 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01975929 0,07793581 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01975929 0,07780825 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01975929 0,07768111 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01975929 0,07755439 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01975929 0,07742808 ! toxin metabolic process GO:0009404 11 6 0,000 0,01975929 0,07730218 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01975929 0,07717669 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01975929 0,07705161 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01975929 0,07692693 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01975929 0,07680265 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01975929 0,07667878 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01975929 0,0765553 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01975929 0,07643222 ! thymic T cell selection GO:0045061 12 6 0,000 0,01975929 0,07630954 ! protein lipoylation GO:0009249 10 6 0,000 0,01975929 0,07618725 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01975929 0,07606535 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01975929 0,07594384 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01975929 0,07582271 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01975929 0,07570198 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01975929 0,07558162 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01975929 0,07546165 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01975929 0,07534206 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01975929 0,07522285 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01975929 0,07510402 ! hyperosmotic response GO:0006972 9 6 0,000 0,01975929 0,07498555 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01975929 0,07486747 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01975929 0,07474975 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01975929 0,0746324 ! urea metabolic process GO:0019627 7 6 0,000 0,01975929 0,07451543 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01975929 0,07439881 ! neutrophil activation GO:0042119 8 6 0,000 0,01975929 0,07428256 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01975929 0,07416668 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01975929 0,07405116 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01975929 0,07393599 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01975929 0,07382118 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01975929 0,07370673 ! neuron apoptosis GO:0051402 9 6 0,000 0,01975929 0,07359263 ! nucleoside salvage GO:0043174 9 6 0,000 0,01975929 0,07347889 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01975929 0,0733655 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01975929 0,07325245 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01975929 0,07313976 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01975929 0,07302741 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,01975929 0,0729154 ! carnitine transport GO:0015879 10 6 0,000 0,01975929 0,07280374 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01975929 0,07269242 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01975929 0,07258144 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01975929 0,0724708 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01975929 0,07236049 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01975929 0,07225052 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01975929 0,07214088 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01975929 0,07203158 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01975929 0,0719226 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01975929 0,07181396 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01975929 0,07170564 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01975929 0,07159765 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01975929 0,07148999 ! neural nucleus development GO:0048857 14 6 0,000 0,01975929 0,07138264 ! response to UV-C GO:0010225 11 6 0,000 0,01975929 0,07127562 ! astrocyte development GO:0014002 15 6 0,000 0,01975929 0,07116892 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01975929 0,07106254 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01975929 0,07095648 ! interaction with symbiont GO:0051702 13 6 0,000 0,01975929 0,07085073 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01975929 0,0707453 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01975929 0,07064018 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01975929 0,07053537 ! response to copper ion GO:0046688 10 6 0,000 0,01975929 0,07043088 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01975929 0,07032669 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01975929 0,07022281 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01975929 0,07011924 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01975929 0,07001597 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01975929 0,069913 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01975929 0,06981034 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01975929 0,06970798 ! Schwann cell development GO:0014044 15 6 0,000 0,01975929 0,06960592 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01975929 0,06950415 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01975929 0,06940269 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01975929 0,06930152 ! subpallium development GO:0021544 10 6 0,000 0,01975929 0,06920064 ! histone ubiquitination GO:0016574 8 6 0,000 0,01975929 0,06910006 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01975929 0,06899977 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01975929 0,06889977 ! tetracycline transport GO:0015904 8 6 0,000 0,01975929 0,06880006 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01975929 0,06870064 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01975929 0,0686015 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01975929 0,06850265 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01975929 0,06840409 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01975929 0,06830581 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01975929 0,06820781 ! receptor internalization GO:0031623 10 6 0,000 0,01975929 0,06811009 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01975929 0,06801265 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01975929 0,06791549 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01975929 0,0678186 ! protein deubiquitination GO:0016579 14 6 0,000 0,01975929 0,067722 ! protein destabilization GO:0031648 9 6 0,000 0,01975929 0,06762566 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01975929 0,0675296 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01975929 0,06743382 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01975929 0,0673383 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01975929 0,06724306 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01975929 0,06714808 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01975929 0,06705337 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01975929 0,06695893 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01975929 0,06686476 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01975929 0,06677084 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01975929 0,0666772 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01975929 0,06658381 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01975929 0,06649069 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01975929 0,06639782 ! catecholamine transport GO:0051937 9 6 0,000 0,01975929 0,06630522 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01975929 0,06621287 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01975929 0,06612078 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01975929 0,06602895 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01975929 0,06593737 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01975929 0,06584604 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01975929 0,06575497 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01975929 0,06566415 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01975929 0,06557357 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01975929 0,06548325 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01975929 0,06539318 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01975929 0,06530335 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,01982112 0,06541786 GO:0035113|embryonic appendage morphogenesis, ! developmental maturation GO:0021700 116 66 1,000 0,02039689 0,06722591 ! lung development GO:0030324 144 67 1,000 0,02097961 0,0690519 ! chromosome segregation GO:0007059 113 67 1,000 0,02097961 0,06895756 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,02097961 0,06886349 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,02156923 0,0707024 ! viral reproduction GO:0016032 134 68 1,000 0,02156923 0,0706062 ! urogenital system development GO:0001655 137 69 1,000 0,02216569 0,07246014 ! appendage morphogenesis GO:0035107 135 70 1,000 0,02276896 0,07433123 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,02276896 0,07423051 ! tRNA transcription GO:0009304 14 7 0,000 0,02301471 0,07493016 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02301471 0,07482891 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02301471 0,07472792 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02301471 0,07462721 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02301471 0,07452677 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02301471 0,0744266 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02301471 0,0743267 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02301471 0,07422707 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02301471 0,0741277 ! prostate gland development GO:0030850 13 7 0,000 0,02301471 0,0740286 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02301471 0,07392976 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02301471 0,07383119 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02301471 0,07373288 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02301471 0,07363483 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02301471 0,07353704 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02301471 0,07343951 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02301471 0,07334224 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02301471 0,07324523 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02301471 0,07314847 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02301471 0,07305197 ! glycolipid transport GO:0046836 10 7 0,000 0,02301471 0,07295572 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02301471 0,07285973 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02301471 0,07276398 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02301471 0,07266849 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02301471 0,07257325 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02301471 0,07247826 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02301471 0,07238352 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02301471 0,07228902 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02301471 0,07219477 ! mRNA stabilization GO:0048255 18 7 0,000 0,02301471 0,07210077 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02301471 0,07200701 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02301471 0,0719135 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02301471 0,07182022 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02301471 0,07172719 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02301471 0,0716344 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02301471 0,07154185 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02301471 0,07144954 ! lipoprotein transport GO:0042953 14 7 0,000 0,02301471 0,07135746 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02301471 0,07126563 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02301471 0,07117403 ! rhythmic behavior GO:0007622 15 7 0,000 0,02301471 0,07108266 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02301471 0,07099153 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02301471 0,07090063 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02301471 0,07080996 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02301471 0,07071953 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02301471 0,07062933 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02301471 0,07053935 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02301471 0,07044961 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02301471 0,07036009 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02301471 0,0702708 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02301471 0,07018174 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02301471 0,0700929 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02301471 0,07000429 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02301471 0,0699159 ! spinal cord patterning GO:0021511 13 7 0,000 0,02301471 0,06982773 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02301471 0,06973979 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02301471 0,06965206 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02301471 0,06956456 ! adrenal gland development GO:0030325 17 7 0,000 0,02301471 0,06947728 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02301471 0,06939022 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02301471 0,06930337 ! ovulation GO:0030728 9 7 0,000 0,02301471 0,06921674 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02301471 0,06913033 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02301471 0,06904413 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02301471 0,06895815 ! microtubule nucleation GO:0007020 20 7 0,000 0,02301471 0,06887238 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02301471 0,06878682 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02301471 0,06870148 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02301471 0,06861635 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02301471 0,06853143 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02301471 0,06844671 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02301471 0,06836221 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02301471 0,06827792 ! galactose metabolic process GO:0006012 13 7 0,000 0,02301471 0,06819383 ! vesicle fusion GO:0006906 17 7 0,000 0,02301471 0,06810995 ! response to dietary excess GO:0002021 8 7 0,000 0,02301471 0,06802628 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02301471 0,06794281 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02301471 0,06785955 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02301471 0,06777649 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02301471 0,06769363 ! organ growth GO:0035265 15 7 0,000 0,02301471 0,06761098 ! purine salvage GO:0043101 10 7 0,000 0,02301471 0,06752853 ! nucleoside transport GO:0015858 8 7 0,000 0,02301471 0,06744627 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02301471 0,06736422 ! parturition GO:0007567 14 7 0,000 0,02301471 0,06728237 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02301471 0,06720072 ! rRNA modification GO:0000154 14 7 0,000 0,02301471 0,06711926 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02301471 0,067038 ! spindle checkpoint GO:0031577 15 7 0,000 0,02301471 0,06695694 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02301471 0,06687608 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02301471 0,06679541 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02301471 0,06671493 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02301471 0,06663465 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02301471 0,06655456 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02301471 0,06647466 ! fibrinolysis GO:0042730 10 7 0,000 0,02301471 0,06639495 ! eating behavior GO:0042755 7 7 0,000 0,02301471 0,06631544 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02301471 0,06623611 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02301471 0,06615698 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02301471 0,06607803 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02301471 0,06599927 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02301471 0,0659207 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02301471 0,06584232 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02301471 0,06576412 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02301471 0,06568611 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02301471 0,06560828 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02301471 0,06553064 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02301471 0,06545318 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02301471 0,06537591 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02301471 0,06529881 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02301471 0,0652219 ! regulation of meiosis GO:0040020 12 7 0,000 0,02301471 0,06514517 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02301471 0,06506862 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02301471 0,06499224 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02301471 0,06491605 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02301471 0,06484004 ! transcription termination GO:0006353 13 7 0,000 0,02301471 0,0647642 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02301471 0,06468854 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02301471 0,06461306 ! anaphase GO:0051322 17 7 0,000 0,02301471 0,06453775 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02301471 0,06446262 ! axonal fasciculation GO:0007413 18 7 0,000 0,02301471 0,06438766 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02301471 0,06431288 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02301471 0,06423827 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02301471 0,06416384 ! diuresis GO:0030146 12 7 0,000 0,02301471 0,06408957 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02301471 0,06401548 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02301471 0,06394156 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02301471 0,06386781 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02301471 0,06379423 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02301471 0,06372082 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02301471 0,06364758 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02301471 0,0635745 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02301471 0,0635016 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02301471 0,06342886 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02301471 0,06335628 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02301471 0,06328388 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02301471 0,06321163 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02301471 0,06313956 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02301471 0,06306764 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02301471 0,06299589 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02301471 0,06292431 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02301471 0,06285288 ! adult feeding behavior GO:0008343 9 7 0,000 0,02301471 0,06278162 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02301471 0,06271052 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02301471 0,06263958 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02301471 0,0625688 ! muscle adaptation GO:0043500 14 7 0,000 0,02301471 0,06249818 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02301471 0,06242772 ! retina homeostasis GO:0001895 12 7 0,000 0,02301471 0,06235742 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02301471 0,06228728 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02301471 0,06221729 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02301471 0,06214747 ! protein prenylation GO:0018342 18 7 0,000 0,02301471 0,06207779 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02301471 0,06200828 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02301471 0,06193892 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02301471 0,06186971 ! appendage development GO:0048736 136 71 1,000 0,02337897 0,0627788 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 1,000 0,02337897 0,06270881 ! regulation of immune effector process GO:0002697 137 71 1,000 0,02337897 0,06263898 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02399568 0,06421981 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,02399568 0,06414845 ! carbohydrate transport GO:0008643 110 72 1,000 0,02399568 0,06407725 ! respiratory system development GO:0060541 153 72 1,000 0,02399568 0,06400622 ! learning or memory GO:0007611 147 73 1,000 0,02461903 0,06559623 ! regulation of blood pressure GO:0008217 125 73 1,000 0,02461903 0,06552367 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,02524899 0,06712603 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02524899 0,06705194 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,02588548 0,06866645 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02588548 0,06859083 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02625943 0,06950516 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02625943 0,06942878 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02625943 0,06935257 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02625943 0,06927652 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02625943 0,06920064 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02625943 0,06912493 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02625943 0,06904939 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02625943 0,06897401 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02625943 0,06889879 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02625943 0,06882374 ! meiotic prophase I GO:0007128 13 8 0,000 0,02625943 0,06874885 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02625943 0,06867412 ! oligopeptide transport GO:0006857 15 8 0,000 0,02625943 0,06859955 ! UTP metabolic process GO:0046051 8 8 0,000 0,02625943 0,06852515 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02625943 0,06845091 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02625943 0,06837683 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02625943 0,06830291 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02625943 0,06822915 ! succinate metabolic process GO:0006105 14 8 0,000 0,02625943 0,06815554 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02625943 0,0680821 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02625943 0,06800881 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02625943 0,06793569 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02625943 0,06786272 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02625943 0,0677899 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02625943 0,06771724 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02625943 0,06764474 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02625943 0,06757239 ! reflex GO:0060004 16 8 0,000 0,02625943 0,0675002 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02625943 0,06742816 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02625943 0,06735628 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02625943 0,06728455 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02625943 0,06721297 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02625943 0,06714154 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02625943 0,06707026 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02625943 0,06699914 ! pigment granule organization GO:0048753 16 8 0,000 0,02625943 0,06692817 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02625943 0,06685734 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02625943 0,06678667 ! histidine metabolic process GO:0006547 16 8 0,000 0,02625943 0,06671614 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02625943 0,06664577 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02625943 0,06657554 ! glycine catabolic process GO:0006546 13 8 0,000 0,02625943 0,06650546 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02625943 0,06643553 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02625943 0,06636574 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02625943 0,06629611 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02625943 0,06622661 ! melanin metabolic process GO:0006582 15 8 0,000 0,02625943 0,06615727 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02625943 0,06608806 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02625943 0,06601901 ! macrophage activation GO:0042116 12 8 0,000 0,02625943 0,06595009 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02625943 0,06588132 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02625943 0,0658127 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02625943 0,06574421 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02625943 0,06567587 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02625943 0,06560767 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02625943 0,06553961 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02625943 0,0654717 ! osteoblast development GO:0002076 16 8 0,000 0,02625943 0,06540392 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02625943 0,06533629 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02625943 0,06526879 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02625943 0,06520143 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02625943 0,06513422 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02625943 0,06506714 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02625943 0,06500019 ! response to UV-B GO:0010224 16 8 0,000 0,02625943 0,06493339 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02625943 0,06486672 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02625943 0,06480019 ! intermediate filament organization GO:0045109 12 8 0,000 0,02625943 0,0647338 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02625943 0,06466754 ! cellular extravasation GO:0045123 12 8 0,000 0,02625943 0,06460142 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02625943 0,06453543 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02625943 0,06446958 ! response to antibiotic GO:0046677 11 8 0,000 0,02625943 0,06440386 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02625943 0,06433828 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02625943 0,06427283 ! DNA topological change GO:0006265 12 8 0,000 0,02625943 0,06420751 ! response to tropane GO:0014073 15 8 0,000 0,02625943 0,06414232 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,02625943 0,06407727 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02625943 0,06401235 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02625943 0,06394756 ! mast cell activation GO:0045576 14 8 0,000 0,02625943 0,0638829 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02625943 0,06381837 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02625943 0,06375397 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02625943 0,06368971 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02625943 0,06362557 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02625943 0,06356156 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02625943 0,06349768 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02625943 0,06343392 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02625943 0,0633703 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02625943 0,0633068 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02625943 0,06324343 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02625943 0,06318019 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02625943 0,06311707 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02625943 0,06305408 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02625943 0,06299122 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02625943 0,06292847 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02625943 0,06286586 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02625943 0,06280337 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02625943 0,062741 ! hormone catabolic process GO:0042447 17 8 0,000 0,02625943 0,06267876 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02625943 0,06261664 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02625943 0,06255464 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02625943 0,06249277 ! ATP catabolic process GO:0006200 11 8 0,000 0,02625943 0,06243102 ! blastocyst growth GO:0001832 19 8 0,000 0,02625943 0,06236939 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02625943 0,06230788 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02625943 0,06224649 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02625943 0,06218523 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02625943 0,06212408 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02625943 0,06206305 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02625943 0,06200215 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02625943 0,06194136 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02625943 0,06188069 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02625943 0,06182015 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02625943 0,06175972 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02625943 0,0616994 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02625943 0,06163921 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02625943 0,06157913 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02625943 0,06151917 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02625943 0,06145933 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02625943 0,0613996 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02625943 0,06133999 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,02652848 0,06190836 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,02783376 0,0648915 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,02783376 0,06482868 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02849595 0,06630682 ! muscle cell differentiation GO:0042692 159 80 1,000 0,02916444 0,06779676 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,02916444 0,06773132 ! regulation of developmental growth GO:0048638 15 9 0,000 0,02949348 0,06842943 ! axon extension GO:0048675 15 9 0,000 0,02949348 0,0683635 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02949348 0,06829771 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,02949348 0,06823204 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02949348 0,06816649 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02949348 0,06810107 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02949348 0,06803578 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02949348 0,06797061 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02949348 0,06790557 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02949348 0,06784065 ! phosphate transport GO:0006817 19 9 0,000 0,02949348 0,06777585 ! reproductive behavior GO:0019098 19 9 0,000 0,02949348 0,06771118 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02949348 0,06764663 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02949348 0,06758221 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02949348 0,0675179 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02949348 0,06745372 ! GTP metabolic process GO:0046039 9 9 0,000 0,02949348 0,06738966 ! RNA methylation GO:0001510 15 9 0,000 0,02949348 0,06732573 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02949348 0,06726191 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02949348 0,06719822 ! artery development GO:0060840 24 9 0,000 0,02949348 0,06713464 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02949348 0,06707119 ! regulation of glycolysis GO:0006110 21 9 0,000 0,02949348 0,06700785 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02949348 0,06694464 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02949348 0,06688154 ! chemosensory behavior GO:0007635 20 9 0,000 0,02949348 0,06681857 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02949348 0,06675571 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02949348 0,06669297 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02949348 0,06663034 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02949348 0,06656784 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02949348 0,06650545 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02949348 0,06644318 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02949348 0,06638103 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02949348 0,06631899 ! protein targeting to ER GO:0045047 22 9 0,000 0,02949348 0,06625707 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02949348 0,06619526 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02949348 0,06613357 ! T cell selection GO:0045058 23 9 0,000 0,02949348 0,06607199 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02949348 0,06601053 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02949348 0,06594918 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02949348 0,06588794 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02949348 0,06582682 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02949348 0,06576582 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02949348 0,06570492 ! mannose metabolic process GO:0006013 13 9 0,000 0,02949348 0,06564414 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02949348 0,06558347 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02949348 0,06552291 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02949348 0,06546247 ! receptor clustering GO:0043113 18 9 0,000 0,02949348 0,06540214 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02949348 0,06534191 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02949348 0,0652818 ! ruffle organization GO:0031529 15 9 0,000 0,02949348 0,0652218 ! retinol metabolic process GO:0042572 18 9 0,000 0,02949348 0,06516191 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02949348 0,06510213 ! behavioral fear response GO:0001662 22 9 0,000 0,02949348 0,06504245 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02949348 0,06498289 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02949348 0,06492344 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02949348 0,06486409 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,02949348 0,06480486 ! oligodendrocyte development GO:0014003 10 9 0,000 0,02949348 0,06474573 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02949348 0,06468671 ! segment specification GO:0007379 13 9 0,000 0,02949348 0,06462779 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02949348 0,06456899 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02949348 0,06451029 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02949348 0,0644517 ! response to amine stimulus GO:0014075 13 9 0,000 0,02949348 0,06439321 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02949348 0,06433483 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02949348 0,06427655 ! erythrocyte development GO:0048821 15 9 0,000 0,02949348 0,06421839 ! gas homeostasis GO:0033483 16 9 0,000 0,02949348 0,06416032 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02949348 0,06410236 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02949348 0,06404451 ! renal water homeostasis GO:0003091 14 9 0,000 0,02949348 0,06398676 ! postreplication repair GO:0006301 22 9 0,000 0,02949348 0,06392911 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02949348 0,06387157 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02949348 0,06381413 ! icosanoid secretion GO:0032309 15 9 0,000 0,02949348 0,0637568 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02949348 0,06369957 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02949348 0,06364244 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02949348 0,06358541 ! regulation of cell division GO:0051302 15 9 0,000 0,02949348 0,06352848 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02949348 0,06347166 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02949348 0,06341494 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02949348 0,06335832 ! sterol catabolic process GO:0016127 11 9 0,000 0,02949348 0,0633018 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02949348 0,06324538 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02949348 0,06318906 ! S phase GO:0051320 9 9 0,000 0,02949348 0,06313284 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02949348 0,06307673 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02949348 0,06302071 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02949348 0,06296479 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02949348 0,06290897 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02949348 0,06285325 ! purine base metabolic process GO:0006144 21 9 0,000 0,02949348 0,06279763 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02949348 0,0627421 ! pigment granule transport GO:0051904 17 9 0,000 0,02949348 0,06268668 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02949348 0,06263135 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02949348 0,06257612 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02949348 0,06252098 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02949348 0,06246595 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02949348 0,06241101 ! mitochondrion localization GO:0051646 15 9 0,000 0,02949348 0,06235617 ! response to hypoxia GO:0001666 171 81 1,000 0,02983919 0,06303168 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02983919 0,06297639 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,03052014 0,0643571 ! response to drug GO:0042493 143 82 1,000 0,03052014 0,06430075 ! response to oxygen levels GO:0070482 176 83 1,000 0,03120725 0,06569084 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,0327169 0,06880844 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,0327169 0,06874835 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,0327169 0,06868836 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,0327169 0,06862847 ! synapsis GO:0007129 13 10 0,000 0,0327169 0,06856869 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,0327169 0,06850902 ! N-glycan processing GO:0006491 20 10 0,000 0,0327169 0,06844944 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,0327169 0,06838997 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,0327169 0,06833061 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,0327169 0,06827134 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,0327169 0,06821218 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,0327169 0,06815312 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,0327169 0,06809417 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,0327169 0,06803531 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,0327169 0,06797656 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,0327169 0,06791791 ! androgen metabolic process GO:0008209 17 10 0,000 0,0327169 0,06785936 ! phospholipid efflux GO:0033700 16 10 0,000 0,0327169 0,06780091 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,0327169 0,06774256 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,0327169 0,06768432 ! lung alveolus development GO:0048286 26 10 0,000 0,0327169 0,06762617 ! pathogenesis GO:0009405 13 10 0,000 0,0327169 0,06756812 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,0327169 0,06751017 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,0327169 0,06745232 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,0327169 0,06739457 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,0327169 0,06733692 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,0327169 0,06727937 ! endoderm development GO:0007492 16 10 0,000 0,0327169 0,06722191 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,0327169 0,06716456 ! arginine catabolic process GO:0006527 13 10 0,000 0,0327169 0,0671073 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,0327169 0,06705014 ! proline metabolic process GO:0006560 13 10 0,000 0,0327169 0,06699307 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,0327169 0,0669361 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,0327169 0,06687923 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,0327169 0,06682246 ! V(D)J recombination GO:0033151 28 10 0,000 0,0327169 0,06676578 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,0327169 0,0667092 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,0327169 0,06665272 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,0327169 0,06659633 ! B cell proliferation GO:0042100 18 10 0,000 0,0327169 0,06654003 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,0327169 0,06648383 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,0327169 0,06642773 ! multicellular organism growth GO:0035264 18 10 0,000 0,0327169 0,06637172 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,0327169 0,0663158 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,0327169 0,06625998 ! epithelial cell development GO:0002064 20 10 0,000 0,0327169 0,06620425 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,0327169 0,06614862 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,0327169 0,06609308 ! macroautophagy GO:0016236 17 10 0,000 0,0327169 0,06603763 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,0327169 0,06598228 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,0327169 0,06592702 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,0327169 0,06587185 ! copper ion homeostasis GO:0055070 13 10 0,000 0,0327169 0,06581677 ! regulation of bone resorption GO:0045124 25 10 0,000 0,0327169 0,06576179 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,0327169 0,06570689 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,0327169 0,06565209 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,0327169 0,06559738 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,0327169 0,06554276 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,0327169 0,06548824 ! blastoderm segmentation GO:0007350 18 10 0,000 0,0327169 0,0654338 ! response to dsRNA GO:0043331 20 10 0,000 0,0327169 0,06537945 ! DNA ligation GO:0006266 19 10 0,000 0,0327169 0,06532519 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,0327169 0,06527103 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,0327169 0,06521695 ! melanosome localization GO:0032400 16 10 0,000 0,0327169 0,06516296 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,0327169 0,06510906 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,0327169 0,06505526 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,0327169 0,06500154 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,0327169 0,0649479 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,0327169 0,06489436 ! mRNA cleavage GO:0006379 17 10 0,000 0,0327169 0,06484091 ! protein sumoylation GO:0016925 15 10 0,000 0,0327169 0,06478754 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,0327169 0,06473426 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,0327169 0,06468107 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,0327169 0,06462796 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,0327169 0,06457495 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,0327169 0,06452202 ! salivary gland development GO:0007431 27 10 0,000 0,0327169 0,06446917 ! prophase GO:0051324 15 10 0,000 0,0327169 0,06441641 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,0327169 0,06436374 ! apical protein localization GO:0045176 15 10 0,000 0,0327169 0,06431116 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,0327169 0,06425866 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,0327169 0,06420625 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,0327169 0,06415392 ! midbrain development GO:0030901 13 10 0,000 0,0327169 0,06410168 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,0327169 0,06404952 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,0327169 0,06399745 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,0327169 0,06394546 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,0327169 0,06389355 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,0327169 0,06384173 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,0327169 0,06379 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,0327169 0,06373835 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,0327169 0,06368678 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,0327169 0,06363529 ! oocyte development GO:0048599 17 10 0,000 0,0327169 0,06358389 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,0327169 0,06353257 ! blastocyst formation GO:0001825 17 10 0,000 0,0327169 0,06348134 ! cerebellar cortex development GO:0021695 15 10 0,000 0,0327169 0,06343018 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,0327169 0,06337911 ! activation of innate immune response GO:0002218 12 10 0,000 0,0327169 0,06332812 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,0327169 0,06327722 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,0327169 0,06322639 ! response to nicotine GO:0035094 20 10 0,000 0,0327169 0,06317565 ! establishment of cell polarity GO:0030010 16 10 0,000 0,0327169 0,06312499 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,0327169 0,06307441 ! tube morphogenesis GO:0035239 176 86 1,000 0,03330504 0,06415687 ! mitochondrion organization GO:0007005 148 86 1,000 0,03330504 0,06410554 ! regulation of DNA binding GO:0051101 155 88 1,000 0,03473349 0,06680159 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,03545656 0,06813776 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03592972 0,06899194 ! respiratory burst GO:0045730 17 11 0,000 0,03592972 0,06893692 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03592972 0,06888199 ! neuron fate specification GO:0048665 17 11 0,000 0,03592972 0,06882715 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03592972 0,06877239 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03592972 0,06871773 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03592972 0,06866314 ! thyroid gland development GO:0030878 26 11 0,000 0,03592972 0,06860865 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03592972 0,06855424 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03592972 0,06849992 ! response to pain GO:0048265 24 11 0,000 0,03592972 0,06844568 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03592972 0,06839153 ! T cell proliferation GO:0042098 26 11 0,000 0,03592972 0,06833747 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03592972 0,06828349 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03592972 0,0682296 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03592972 0,06817579 ! bone resorption GO:0045453 16 11 0,000 0,03592972 0,06812206 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03592972 0,06806842 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03592972 0,06801487 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03592972 0,0679614 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03592972 0,06790801 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03592972 0,06785471 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03592972 0,06780149 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03592972 0,06774835 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03592972 0,0676953 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03592972 0,06764233 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03592972 0,06758944 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03592972 0,06753664 ! UV protection GO:0009650 19 11 0,000 0,03592972 0,06748392 ! adult heart development GO:0007512 14 11 0,000 0,03592972 0,06743128 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03592972 0,06737872 ! temperature homeostasis GO:0001659 17 11 0,000 0,03592972 0,06732625 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03592972 0,06727385 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03592972 0,06722154 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03592972 0,06716931 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03592972 0,06711716 ! regulation of organ growth GO:0046620 13 11 0,000 0,03592972 0,06706509 ! pigment granule localization GO:0051875 20 11 0,000 0,03592972 0,0670131 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03592972 0,06696119 ! vasoconstriction GO:0042310 18 11 0,000 0,03592972 0,06690936 ! embryonic axis specification GO:0000578 18 11 0,000 0,03592972 0,06685762 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03592972 0,06680595 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03592972 0,06675436 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03592972 0,06670285 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03592972 0,06665143 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03592972 0,06660008 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03592972 0,06654881 ! zymogen activation GO:0031638 15 11 0,000 0,03592972 0,06649761 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03592972 0,0664465 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03592972 0,06639547 ! nucleosome positioning GO:0016584 15 11 0,000 0,03592972 0,06634451 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03592972 0,06629363 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03592972 0,06624283 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03592972 0,06619211 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03592972 0,06614147 ! acid secretion GO:0046717 18 11 0,000 0,03592972 0,0660909 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03592972 0,06604041 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03592972 0,06599 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03592972 0,06593966 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03592972 0,0658894 ! oocyte differentiation GO:0009994 18 11 0,000 0,03592972 0,06583922 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03592972 0,06578912 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03592972 0,06573909 ! cholesterol efflux GO:0033344 19 11 0,000 0,03592972 0,06568913 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03592972 0,06563926 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03592972 0,06558945 ! germ cell migration GO:0008354 25 11 0,000 0,03592972 0,06553973 ! embryonic gut development GO:0048566 15 11 0,000 0,03592972 0,06549008 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03592972 0,0654405 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03592972 0,065391 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03592972 0,06534157 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03592972 0,06529222 ! defense response to fungus GO:0050832 13 11 0,000 0,03592972 0,06524294 ! developmental induction GO:0031128 19 11 0,000 0,03592972 0,06519374 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03592972 0,06514461 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03592972 0,06509556 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03592972 0,06504658 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03592972 0,06499767 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03592972 0,06494883 ! regulation of embryonic development GO:0045995 27 11 0,000 0,03592972 0,06490007 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03618545 0,06531298 ! sterol metabolic process GO:0016125 152 91 1,000 0,03692013 0,06658908 ! vitamin metabolic process GO:0006766 139 92 1,000 0,03766055 0,06787362 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03840666 0,06916648 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03840666 0,06911475 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03913197 0,07036735 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03913197 0,0703148 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03913197 0,07026233 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,03913197 0,07020993 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03913197 0,07015762 ! virus-host interaction GO:0019048 29 12 0,000 0,03913197 0,07010538 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03913197 0,07005321 ! cartilage condensation GO:0001502 20 12 0,000 0,03913197 0,07000113 ! mating GO:0007618 17 12 0,000 0,03913197 0,06994912 ! protein complex disassembly GO:0043241 27 12 0,000 0,03913197 0,06989719 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03913197 0,06984534 ! hippocampus development GO:0021766 26 12 0,000 0,03913197 0,06979357 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03913197 0,06974187 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03913197 0,06969024 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03913197 0,0696387 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03913197 0,06958723 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03913197 0,06953583 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03913197 0,06948452 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03913197 0,06943327 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03913197 0,06938211 ! drug transport GO:0015893 16 12 0,000 0,03913197 0,06933102 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03913197 0,06928 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03913197 0,06922906 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03913197 0,06917819 ! focal adhesion formation GO:0048041 35 12 0,000 0,03913197 0,0691274 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03913197 0,06907668 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03913197 0,06902604 ! forebrain cell migration GO:0021885 21 12 0,000 0,03913197 0,06897547 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03913197 0,06892498 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03913197 0,06887456 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03913197 0,06882421 ! fear response GO:0042596 26 12 0,000 0,03913197 0,06877394 ! monoamine transport GO:0015844 18 12 0,000 0,03913197 0,06872374 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03913197 0,06867361 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03913197 0,06862356 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03913197 0,06857358 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03913197 0,06852367 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03913197 0,06847383 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03913197 0,06842407 ! protein homotetramerization GO:0051289 21 12 0,000 0,03913197 0,06837438 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03913197 0,06832476 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03913197 0,06827521 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03913197 0,06822574 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03913197 0,06817634 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03913197 0,068127 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03913197 0,06807774 ! cranial nerve development GO:0021545 20 12 0,000 0,03913197 0,06802855 ! fucose catabolic process GO:0019317 22 12 0,000 0,03913197 0,06797944 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03913197 0,06793039 ! histone methylation GO:0016571 26 12 0,000 0,03913197 0,06788141 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03913197 0,06783251 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03913197 0,06778367 ! gland morphogenesis GO:0022612 29 12 0,000 0,03913197 0,06773491 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03913197 0,06768621 ! T cell homeostasis GO:0043029 25 12 0,000 0,03913197 0,06763759 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03913197 0,06758903 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03913197 0,06754054 ! spleen development GO:0048536 22 12 0,000 0,03913197 0,06749213 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03913197 0,06744378 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03913197 0,0673955 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03913197 0,0673473 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03913197 0,06729916 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03913197 0,06725109 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,03913197 0,06720308 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03913197 0,06715515 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03913197 0,06710728 ! response to cold GO:0009409 17 12 0,000 0,03913197 0,06705949 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03913197 0,06701176 ! female pregnancy GO:0007565 164 94 1,000 0,03915842 0,06700935 ! transcription initiation GO:0006352 153 94 1,000 0,03915842 0,06696173 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03915842 0,06691417 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,04222103 0,07209639 GO:0016054|organic acid catabolic process, ! cGMP metabolic process GO:0046068 18 13 0,000 0,04232369 0,07222043 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04232369 0,07216924 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04232369 0,07211813 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04232369 0,07206709 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,04232369 0,07201613 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04232369 0,07196523 ! lipid localization GO:0010876 28 13 0,000 0,04232369 0,07191441 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04232369 0,07186366 ! organelle fusion GO:0048284 32 13 0,000 0,04232369 0,07181298 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04232369 0,07176237 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04232369 0,07171183 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04232369 0,07166137 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04232369 0,07161097 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04232369 0,07156065 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04232369 0,0715104 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04232369 0,07146021 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04232369 0,0714101 ! methionine metabolic process GO:0006555 27 13 0,000 0,04232369 0,07136006 ! plasma membrane organization GO:0007009 24 13 0,000 0,04232369 0,07131009 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04232369 0,07126018 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04232369 0,07121035 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04232369 0,07116059 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04232369 0,0711109 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04232369 0,07106127 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04232369 0,07101172 ! exocrine system development GO:0035272 32 13 0,000 0,04232369 0,07096223 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,04232369 0,07091282 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04232369 0,07086347 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04232369 0,07081419 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04232369 0,07076498 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04232369 0,07071584 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04232369 0,07066676 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04232369 0,07061776 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04232369 0,07056882 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04232369 0,07051995 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04232369 0,07047114 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04232369 0,07042241 ! ribosome assembly GO:0042255 17 13 0,000 0,04232369 0,07037374 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04232369 0,07032514 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04232369 0,07027661 ! chromatin silencing GO:0006342 26 13 0,000 0,04232369 0,07022814 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04232369 0,07017974 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04232369 0,07013141 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04232369 0,07008314 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04232369 0,07003494 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04232369 0,06998681 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,04232369 0,06993874 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04232369 0,06989074 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04232369 0,0698428 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04232369 0,06979493 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04232369 0,06974713 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04232369 0,06969939 ! embryonic placenta development GO:0001892 23 13 0,000 0,04232369 0,06965171 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04232369 0,0696041 ! insulin secretion GO:0030073 23 13 0,000 0,04232369 0,06955656 ! actin filament polymerization GO:0030041 24 13 0,000 0,04232369 0,06950908 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04232369 0,06946167 ! acrosome reaction GO:0007340 18 13 0,000 0,04232369 0,06941432 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,04300036 0,07047607 GO:0060538|skeletal muscle organ development, ! rRNA transcription GO:0009303 25 14 0,000 0,04550492 0,07453018 ! lactation GO:0007595 26 14 0,000 0,04550492 0,07447948 ! reproductive cellular process GO:0048610 20 14 0,000 0,04550492 0,07442885 ! tRNA modification GO:0006400 20 14 0,000 0,04550492 0,07437828 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04550492 0,07432779 ! regulation of S phase GO:0033261 23 14 0,000 0,04550492 0,07427736 ! water transport GO:0006833 21 14 0,000 0,04550492 0,07422701 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04550492 0,07417672 ! non-recombinational repair GO:0000726 25 14 0,000 0,04550492 0,0741265 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04550492 0,07407634 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04550492 0,07402626 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04550492 0,07397624 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04550492 0,07392629 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04550492 0,07387641 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04550492 0,07382659 ! palate development GO:0060021 31 14 0,000 0,04550492 0,07377684 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04550492 0,07372716 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,04550492 0,07367755 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04550492 0,073628 ! arginine metabolic process GO:0006525 17 14 0,000 0,04550492 0,07357852 ! regulation of heart rate GO:0002027 24 14 0,000 0,04550492 0,0735291 ! organic alcohol transport GO:0015850 29 14 0,000 0,04550492 0,07347975 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,04550492 0,07343047 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04550492 0,07338126 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04550492 0,07333211 GO:0060675|ureteric bud morphogenesis, ! neutral amino acid transport GO:0015804 26 14 0,000 0,04550492 0,07328302 ! L-amino acid transport GO:0015807 30 14 0,000 0,04550492 0,073234 ! bone mineralization GO:0030282 17 14 0,000 0,04550492 0,07318505 ! stem cell development GO:0048864 43 14 0,000 0,04550492 0,07313616 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,04550492 0,07308734 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04550492 0,07303858 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04550492 0,07298989 ! cerebellum development GO:0021549 21 14 0,000 0,04550492 0,07294126 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04550492 0,0728927 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04550492 0,0728442 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04550492 0,07279577 ! cofactor transport GO:0051181 26 14 0,000 0,04550492 0,0727474 ! NADP metabolic process GO:0006739 24 14 0,000 0,04550492 0,07269909 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04550492 0,07265085 ! intestinal absorption GO:0050892 25 14 0,000 0,04550492 0,07260267 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04550492 0,07255456 ! oxygen transport GO:0015671 21 14 0,000 0,04550492 0,07250651 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04550492 0,07245853 ! male genitalia development GO:0030539 24 14 0,000 0,04550492 0,0724106 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04550492 0,07236275 ! regulation of axon extension GO:0030516 37 14 0,000 0,04550492 0,07231495 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04550492 0,07226722 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04867568 0,07725178 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04867568 0,07720085 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04867568 0,07714999 ! superoxide anion generation GO:0042554 20 15 0,000 0,04867568 0,0770992 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04867568 0,07704848 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04867568 0,07699783 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04867568 0,07694724 ! copper ion transport GO:0006825 20 15 0,000 0,04867568 0,07689671 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04867568 0,07684625 ! sulfate transport GO:0008272 23 15 0,000 0,04867568 0,07679586 ! response to cAMP GO:0051591 22 15 0,000 0,04867568 0,07674554 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04867568 0,07669528 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04867568 0,07664509 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04867568 0,07659496 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04867568 0,0765449 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04867568 0,0764949 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04867568 0,07644497 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04867568 0,0763951 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04867568 0,0763453 ! pituitary gland development GO:0021983 29 15 0,000 0,04867568 0,07629556 ! vesicle coating GO:0006901 33 15 0,000 0,04867568 0,07624589 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04867568 0,07619629 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04867568 0,07614674 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04867568 0,07609727 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04867568 0,07604785 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04867568 0,0759985 ! histone deacetylation GO:0016575 20 15 0,000 0,04867568 0,07594922 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04867568 0,07589999 ! tissue regeneration GO:0042246 26 15 0,000 0,04867568 0,07585084 ! water homeostasis GO:0030104 27 15 0,000 0,04867568 0,07580174 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04867568 0,07575271 ! muscle maintenance GO:0046716 26 15 0,000 0,04867568 0,07570374 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04867568 0,07565484 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04867568 0,075606 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04867568 0,07555722 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04867568 0,07550851 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04867568 0,07545985 ! cell killing GO:0001906 29 15 0,000 0,04867568 0,07541126 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04867568 0,07536274 ! detection of bacterium GO:0016045 18 15 0,000 0,04867568 0,07531427 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04867568 0,07526587 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04867568 0,07521753 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04867568 0,07516925 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04867568 0,07512103 ! peptide hormone processing GO:0016486 23 15 0,000 0,04867568 0,07507288 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,05183602 0,07989587 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,05183602 0,07984472 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,05183602 0,07979364 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,05183602 0,07974262 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,05183602 0,07969167 ! bone remodeling GO:0046849 27 16 0,000 0,05183602 0,07964078 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,05183602 0,07958996 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,05183602 0,0795392 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,05183602 0,0794885 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,05183602 0,07943787 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,05183602 0,07938731 ! startle response GO:0001964 28 16 0,000 0,05183602 0,07933681 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,05183602 0,07928637 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,05183602 0,079236 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,05183602 0,07918569 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,05183602 0,07913544 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,05183602 0,07908526 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,05183602 0,07903515 ! protein polyubiquitination GO:0000209 34 16 0,000 0,05183602 0,07898509 ! glutamate metabolic process GO:0006536 22 16 0,000 0,05183602 0,0789351 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,05183602 0,07888517 ! response to osmotic stress GO:0006970 25 16 0,000 0,05183602 0,07883531 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,05183602 0,07878551 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,05183602 0,07873577 ! fructose metabolic process GO:0006000 25 16 0,000 0,05183602 0,07868609 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05183602 0,07863648 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,05183602 0,07858693 ! intermediate filament-based process GO:0045103 32 16 0,000 0,05183602 0,07853744 ! axon cargo transport GO:0008088 43 16 0,000 0,05183602 0,07848802 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,05183602 0,07843865 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,05183602 0,07838935 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,05183602 0,07834011 ! DNA replication initiation GO:0006270 27 16 0,000 0,05183602 0,07829094 ! neuron recognition GO:0008038 35 16 0,000 0,05183602 0,07824182 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,05183602 0,07819277 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,05183602 0,07814377 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,05183602 0,07809484 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,05183602 0,07804597 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,05183602 0,07799716 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,05183602 0,07794841 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,05183602 0,07789973 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,05183602 0,0778511 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05183602 0,07780253 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,05183602 0,07775403 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,05183602 0,07770558 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,05183602 0,0776572 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,05183602 0,07760887 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05498596 0,08227377 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05498596 0,08222264 ! metencephalon development GO:0022037 30 17 0,000 0,05498596 0,08217157 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,05498596 0,08212056 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05498596 0,08206962 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05498596 0,08201874 ! signal complex assembly GO:0007172 41 17 0,000 0,05498596 0,08196792 ! endothelial cell migration GO:0043542 28 17 0,000 0,05498596 0,08191716 ! inositol metabolic process GO:0006020 28 17 0,000 0,05498596 0,08186647 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05498596 0,08181584 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05498596 0,08176528 ! glial cell development GO:0021782 27 17 0,000 0,05498596 0,08171477 ! limbic system development GO:0021761 36 17 0,000 0,05498596 0,08166433 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05498596 0,08161395 ! adult walking behavior GO:0007628 33 17 0,000 0,05498596 0,08156364 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05498596 0,08151338 ! heart looping GO:0001947 30 17 0,000 0,05498596 0,08146319 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05498596 0,08141306 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05498596 0,08136299 ! myoblast differentiation GO:0045445 45 17 0,000 0,05498596 0,08131298 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05498596 0,08126303 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,05498596 0,08121315 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05498596 0,08116333 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,05498596 0,08111356 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05498596 0,08106386 ! glycine metabolic process GO:0006544 28 17 0,000 0,05498596 0,08101422 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05498596 0,08096464 ! NAD metabolic process GO:0019674 29 17 0,000 0,05498596 0,08091512 ! membrane budding GO:0006900 37 17 0,000 0,05498596 0,08086566 ! DNA integration GO:0015074 29 17 0,000 0,05498596 0,08081626 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,05498596 0,08076692 ! regulation of protein binding GO:0043393 33 17 0,000 0,05498596 0,08071764 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05498596 0,08066843 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05498596 0,08061927 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05498596 0,08057017 ! genitalia development GO:0048806 30 17 0,000 0,05498596 0,08052113 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05498596 0,08047215 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05498596 0,08042323 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05498596 0,08037437 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05498596 0,08032557 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05498596 0,08027683 ! steroid catabolic process GO:0006706 31 17 0,000 0,05498596 0,08022815 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05498596 0,08017953 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05498596 0,08013096 ! gas transport GO:0015669 25 17 0,000 0,05498596 0,08008246 ! organic cation transport GO:0015695 31 17 0,000 0,05498596 0,08003401 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05498596 0,07998562 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05498596 0,07993729 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05498596 0,07988902 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05498596 0,07984081 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05498596 0,07979265 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05812554 0,0842978 ! neuron maturation GO:0042551 42 18 0,000 0,05812554 0,08424702 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05812554 0,0841963 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05812554 0,08414564 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05812554 0,08409504 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05812554 0,0840445 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05812554 0,08399403 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05812554 0,08394361 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05812554 0,08389325 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05812554 0,08384296 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,05812554 0,08379272 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05812554 0,08374255 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05812554 0,08369243 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05812554 0,08364238 ! response to retinoic acid GO:0032526 26 18 0,000 0,05812554 0,08359238 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05812554 0,08354245 ! response to fungus GO:0009620 21 18 0,000 0,05812554 0,08349257 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05812554 0,08344275 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05812554 0,083393 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05812554 0,0833433 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05812554 0,08329366 ! vitamin transport GO:0051180 27 18 0,000 0,05812554 0,08324408 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05812554 0,08319456 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05812554 0,0831451 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05812554 0,08309569 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05812554 0,08304635 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,05812554 0,08299706 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05812554 0,08294784 ! nerve development GO:0021675 28 18 0,000 0,05812554 0,08289867 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05812554 0,08284956 ! protein secretion GO:0009306 39 19 0,000 0,0612548 0,08725817 ! positive regulation of translation GO:0045727 30 19 0,000 0,0612548 0,08720653 ! negative regulation of defense response GO:0031348 25 19 0,000 0,0612548 0,08715496 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,0612548 0,08710345 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,0612548 0,087052 ! skin development GO:0043588 36 19 0,000 0,0612548 0,08700061 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,0612548 0,08694929 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,0612548 0,08689802 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,0612548 0,08684681 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,0612548 0,08679567 ! bile acid metabolic process GO:0008206 29 19 0,000 0,0612548 0,08674458 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,0612548 0,08669355 ! cerebral cortex development GO:0021987 36 19 0,000 0,0612548 0,08664259 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,0612548 0,08659168 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,0612548 0,08654083 ! heme metabolic process GO:0042168 36 19 0,000 0,0612548 0,08649005 ! actin filament bundle formation GO:0051017 42 19 0,000 0,0612548 0,08643932 ! neuromuscular junction development GO:0007528 34 19 0,000 0,0612548 0,08638865 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,0612548 0,08633804 ! plasma membrane fusion GO:0045026 28 19 0,000 0,0612548 0,08628749 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,0612548 0,086237 ! peptide cross-linking GO:0018149 37 19 0,000 0,0612548 0,08618657 ! protein export from nucleus GO:0006611 36 19 0,000 0,0612548 0,0861362 ! heart process GO:0003015 30 19 0,000 0,0612548 0,08608589 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,0612548 0,08603563 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,0612548 0,08598544 ! cellular pigmentation GO:0033059 36 19 0,000 0,0612548 0,0859353 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,0612548 0,08588522 ! cell-cell junction organization GO:0045216 35 19 0,000 0,0612548 0,0858352 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,0612548 0,08578524 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,0612548 0,08573533 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,0612548 0,08568549 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,0612548 0,0856357 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,0612548 0,08558597 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,0612548 0,0855363 ! cilium assembly GO:0042384 37 19 0,000 0,0612548 0,08548668 ! peptide hormone secretion GO:0030072 31 19 0,000 0,0612548 0,08543713 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06437376 0,08973538 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,06437376 0,08968342 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06437376 0,08963152 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06437376 0,08957968 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06437376 0,0895279 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,06437376 0,08947618 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06437376 0,08942452 ! response to vitamin GO:0033273 31 20 0,000 0,06437376 0,08937292 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06437376 0,08932137 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,06437376 0,08926989 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06437376 0,08921847 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06437376 0,08916711 ! response to alkaloid GO:0043279 38 20 0,000 0,06437376 0,0891158 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06437376 0,08906456 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06437376 0,08901337 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06437376 0,08896224 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06437376 0,08891117 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06437376 0,08886016 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06437376 0,08880921 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06437376 0,08875832 ! body fluid secretion GO:0007589 31 20 0,000 0,06437376 0,08870748 ! peptide secretion GO:0002790 35 20 0,000 0,06437376 0,0886567 ! stem cell differentiation GO:0048863 53 20 0,000 0,06437376 0,08860599 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06437376 0,08855533 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06437376 0,08850472 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06437376 0,08845418 ! sensory perception of pain GO:0019233 30 20 0,000 0,06437376 0,08840369 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06437376 0,08835326 ! diencephalon development GO:0021536 34 20 0,000 0,06437376 0,08830289 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06437376 0,08825257 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06437376 0,08820231 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06437376 0,08815211 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,06437376 0,08810197 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06437376 0,08805188 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06437376 0,08800185 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06437376 0,08795188 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06437376 0,08790197 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06437376 0,08785211 ! actin filament-based movement GO:0030048 43 20 0,000 0,06437376 0,0878023 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06437376 0,08775256 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,06437376 0,08770287 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06437376 0,08765323 ! negative regulation of translation GO:0017148 29 20 0,000 0,06437376 0,08760366 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06437376 0,08755413 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06748246 0,0917304 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06748246 0,0916786 ! hormone secretion GO:0046879 38 21 0,000 0,06748246 0,09162686 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06748246 0,09157518 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06748246 0,09152356 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06748246 0,091472 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06748246 0,0914205 ! axis specification GO:0009798 38 21 0,000 0,06748246 0,09136905 ! ovarian follicle development GO:0001541 35 21 0,000 0,06748246 0,09131766 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06748246 0,09126633 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06748246 0,09121506 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06748246 0,09116384 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06748246 0,09111268 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06748246 0,09106158 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06748246 0,09101054 ! cytolysis GO:0019835 24 21 0,000 0,06748246 0,09095955 ! vasodilation GO:0042311 39 21 0,000 0,06748246 0,09090862 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06748246 0,09085775 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06748246 0,09080694 ! oogenesis GO:0048477 36 21 0,000 0,06748246 0,09075618 ! DNA modification GO:0006304 34 21 0,000 0,06748246 0,09070548 ! collagen fibril organization GO:0030199 59 21 0,000 0,06748246 0,09065483 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06748246 0,09060424 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06748246 0,09055371 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06748246 0,09050323 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06748246 0,09045281 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06748246 0,09040245 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06748246 0,09035214 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06748246 0,09030189 ! collagen catabolic process GO:0030574 28 21 0,000 0,06748246 0,0902517 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06748246 0,09020156 ! gut development GO:0048565 39 21 0,000 0,06748246 0,09015147 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,07058094 0,09423848 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,07058094 0,09418621 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,07058094 0,094134 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,07058094 0,09408185 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,07058094 0,09402975 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,07058094 0,09397772 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,07058094 0,09392574 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,07058094 0,09387382 ! regeneration GO:0031099 41 22 0,000 0,07058094 0,09382195 ! keratinization GO:0031424 28 22 0,000 0,07058094 0,09377015 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,07058094 0,0937184 ! sensory perception of taste GO:0050909 28 22 0,000 0,07058094 0,09366671 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,07058094 0,09361507 ! vacuolar transport GO:0007034 36 22 0,000 0,07058094 0,09356349 ! lysosome organization GO:0007040 41 22 0,000 0,07058094 0,09351197 ! central nervous system neuron development GO:0021954 46 22 0,000 0,07058094 0,0934605 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,07058094 0,0934091 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,07058094 0,09335774 ! fucose metabolic process GO:0006004 39 22 0,000 0,07058094 0,09330645 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,07058094 0,09325521 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,07058094 0,09320403 ! ureteric bud development GO:0001657 43 22 0,000 0,07058094 0,0931529 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,07058094 0,09310183 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,07058094 0,09305081 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,07058094 0,09299986 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,07058094 0,09294895 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,07058094 0,09289811 ! sarcomere organization GO:0045214 30 22 0,000 0,07058094 0,09284731 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,07058094 0,09279658 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,07058094 0,0927459 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,07058094 0,09269527 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,07058094 0,0926447 ! protein stabilization GO:0050821 39 22 0,000 0,07058094 0,09259419 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,07366922 0,096593 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07366922 0,09654039 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07366922 0,09648783 ! gluconeogenesis GO:0006094 33 23 0,000 0,07366922 0,09643534 ! viral genome replication GO:0019079 41 23 0,000 0,07366922 0,0963829 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07366922 0,09633052 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07366922 0,09627819 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07366922 0,09622592 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07366922 0,09617371 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07366922 0,09612156 ! visual behavior GO:0007632 42 23 0,000 0,07366922 0,09606946 ! response to ethanol GO:0045471 46 23 0,000 0,07366922 0,09601742 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07366922 0,09596543 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07366922 0,0959135 ! peroxisome organization GO:0007031 37 23 0,000 0,07366922 0,09586163 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07366922 0,09580981 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07366922 0,09575805 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07366922 0,09570634 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07366922 0,09565469 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,07366922 0,0956031 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07366922 0,09555156 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07366922 0,09550008 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07366922 0,09544865 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07366922 0,09539728 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07366922 0,09534596 ! platelet activation GO:0030168 37 23 0,000 0,07366922 0,0952947 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07366922 0,0952435 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07366922 0,09519235 ! hormone transport GO:0009914 40 23 0,000 0,07366922 0,09514125 ! cell-cell recognition GO:0009988 25 23 0,000 0,07366922 0,09509021 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07366922 0,09503922 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07366922 0,09498829 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,07366922 0,09493741 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07366922 0,09488659 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07366922 0,09483582 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07674735 0,09874552 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,07674735 0,09869274 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07674735 0,09864002 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07674735 0,09858735 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07674735 0,09853475 ! vesicle docking GO:0048278 47 24 0,000 0,07674735 0,0984822 ! spinal cord development GO:0021510 47 24 0,000 0,07674735 0,0984297 ! vacuole organization GO:0007033 43 24 0,000 0,07674735 0,09837726 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07674735 0,09832488 ! digestive system process GO:0022600 39 24 0,000 0,07674735 0,09827255 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07674735 0,09822027 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07674735 0,09816806 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07674735 0,0981159 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07674735 0,09806379 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07674735 0,09801174 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07674735 0,09795974 ! membrane depolarization GO:0051899 39 24 0,000 0,07674735 0,0979078 ! pallium development GO:0021543 49 24 0,000 0,07674735 0,09785592 ! pentose metabolic process GO:0019321 35 24 0,000 0,07674735 0,09780409 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07674735 0,09775231 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07674735 0,09770059 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07674735 0,09764892 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07674735 0,09759731 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07674735 0,09754576 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07674735 0,09749425 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07674735 0,09744281 ! regulation of amine transport GO:0051952 40 24 0,000 0,07674735 0,09739141 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07981534 0,10123127 ! myelination GO:0042552 45 25 0,000 0,07981534 0,10117793 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07981534 0,10112465 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07981534 0,10107143 ! phototransduction GO:0007602 33 25 0,000 0,07981534 0,10101826 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07981534 0,10096515 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07981534 0,1009121 ! sperm motility GO:0030317 31 25 0,000 0,07981534 0,1008591 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07981534 0,10080615 ! receptor metabolic process GO:0043112 46 25 0,000 0,07981534 0,10075326 ! chromosome condensation GO:0030261 45 25 0,000 0,07981534 0,10070043 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07981534 0,10064765 ! neural crest cell development GO:0014032 54 25 0,000 0,07981534 0,10059493 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07981534 0,10054226 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,07981534 0,10048965 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07981534 0,10043709 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07981534 0,10038459 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,07981534 0,10033214 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07981534 0,10027975 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07981534 0,10022741 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07981534 0,10017513 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07981534 0,1001229 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07981534 0,10007072 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07981534 0,1000186 ! telomere organization GO:0032200 43 25 0,000 0,07981534 0,09996654 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07981534 0,09991453 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07981534 0,09986257 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,08287325 0,10363463 ! embryonic pattern specification GO:0009880 44 26 0,000 0,08287325 0,1035808 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,08287325 0,10352702 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,08287325 0,10347329 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,08287325 0,10341963 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,08287325 0,10336601 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,08287325 0,10331245 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,08287325 0,10325895 ! tube lumen formation GO:0035148 50 26 0,000 0,08287325 0,10320551 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,08287325 0,10315211 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,08287325 0,10309878 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,08287325 0,1030455 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,08287325 0,10299227 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,08287325 0,1029391 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,08287325 0,10288598 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,08287325 0,10283292 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,08287325 0,10277992 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,08287325 0,10272696 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,08287325 0,10267407 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,08287325 0,10262122 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,08287325 0,10256843 ! blastocyst development GO:0001824 49 26 0,000 0,08287325 0,1025157 ! leukocyte proliferation GO:0070661 52 26 0,000 0,08287325 0,10246302 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,08287325 0,10241039 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,08287325 0,10235782 ! neuron fate commitment GO:0048663 48 27 0,000 0,08592109 0,1060678 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08592109 0,10601341 ! iron ion transport GO:0006826 59 27 0,000 0,08592109 0,10595907 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08592109 0,10590479 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08592109 0,10585056 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08592109 0,10579639 ! fat cell differentiation GO:0045444 50 27 0,000 0,08592109 0,10574228 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08592109 0,10568822 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08592109 0,10563421 ! autophagy GO:0006914 41 27 0,000 0,08592109 0,10558026 ! male gonad development GO:0008584 44 27 0,000 0,08592109 0,10552637 ! response to toxin GO:0009636 47 27 0,000 0,08592109 0,10547253 ! primary neural tube formation GO:0014020 51 27 0,000 0,08592109 0,10541874 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08592109 0,10536501 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08592109 0,10531133 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08592109 0,10525771 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08592109 0,10520415 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08592109 0,10515064 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,08592109 0,10509718 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08895891 0,10875769 ! circadian rhythm GO:0007623 50 28 0,000 0,08895891 0,10870246 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08895891 0,10864728 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08895891 0,10859215 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08895891 0,10853709 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08895891 0,10848208 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08895891 0,10842712 ! synaptogenesis GO:0007416 42 28 0,000 0,08895891 0,10837222 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08895891 0,10831738 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08895891 0,10826259 ! translational initiation GO:0006413 65 29 0,000 0,09198673 0,11189084 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,09198673 0,1118343 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,09198673 0,11177782 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,09198673 0,11172139 ! catechol metabolic process GO:0009712 54 29 0,000 0,09198673 0,11166502 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,09198673 0,11160871 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,09198673 0,11155246 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,09198673 0,11149626 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,09198673 0,11144012 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,09198673 0,11138403 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,09198673 0,111328 ! cell fate determination GO:0001709 60 29 0,000 0,09198673 0,11127203 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,09198673 0,11121612 ! detection of light stimulus GO:0009583 38 29 0,000 0,09198673 0,11116026 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,09198673 0,11110445 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,09198673 0,11104871 ! tissue homeostasis GO:0001894 48 29 0,000 0,09198673 0,11099302 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,09198673 0,11093738 ! phenol metabolic process GO:0018958 55 30 0,000 0,09500459 0,11451956 ! zinc ion transport GO:0006829 45 30 0,000 0,09500459 0,11446221 ! membrane docking GO:0022406 61 30 0,000 0,09500459 0,11440493 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,09500459 0,11434769 ! regulation of innate immune response GO:0045088 51 30 0,000 0,09500459 0,11429052 ! acute-phase response GO:0006953 49 30 0,000 0,09500459 0,1142334 ! myofibril assembly GO:0030239 47 30 0,000 0,09500459 0,11417634 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,09500459 0,11411934 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,09500459 0,1140624 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,09500459 0,11400551 ! phospholipid transport GO:0015914 51 30 0,000 0,09500459 0,11394867 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,09500459 0,1138919 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,09500459 0,11383518 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,09500459 0,11377852 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,09500459 0,11372191 ! eye morphogenesis GO:0048592 60 30 0,000 0,09500459 0,11366536 ! response to heat GO:0009408 50 30 0,000 0,09500459 0,11360887 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09801252 0,1171476 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09801252 0,11708943 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09801252 0,11703132 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09801252 0,11697327 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09801252 0,11691528 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09801252 0,11685734 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09801252 0,11679946 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09801252 0,11674164 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09801252 0,11668388 ! ovulation cycle process GO:0022602 49 31 0,000 0,09801252 0,11662617 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09801252 0,11656852 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09801252 0,11651093 ! peptide transport GO:0015833 55 31 0,000 0,09801252 0,11645339 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,09801252 0,11639591 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09801252 0,11633849 ! mesoderm formation GO:0001707 69 31 0,000 0,09801252 0,11628112 ! natural killer cell activation GO:0030101 45 31 0,000 0,09801252 0,11622381 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09801252 0,11616656 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09801252 0,11610936 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,09801252 0,11605222 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09801252 0,11599514 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,10101055 0,11948445 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,10101055 0,11942574 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,10101055 0,11936708 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,10101055 0,11930848 ! cholesterol transport GO:0030301 56 32 0,000 0,10101055 0,11924994 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,10101055 0,11919146 ! spliceosome assembly GO:0000245 67 32 0,000 0,10101055 0,11913303 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,10101055 0,11907466 ! metanephros development GO:0001656 74 32 0,000 0,10101055 0,11901635 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,10101055 0,11895809 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,10101055 0,11889989 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,10101055 0,11884175 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,10101055 0,11878367 ! muscle cell development GO:0055001 49 32 0,000 0,10101055 0,11872564 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,10101055 0,11866767 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,10101055 0,11860975 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,10101055 0,11855189 ! ovulation cycle GO:0042698 51 32 0,000 0,10101055 0,11849409 ! peripheral nervous system development GO:0007422 64 32 0,000 0,10101055 0,11843634 ! BMP signaling pathway GO:0030509 64 32 0,000 0,10101055 0,11837865 ! hindbrain development GO:0030902 61 32 0,000 0,10101055 0,11832102 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,10101055 0,11826344 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,10101055 0,11820592 ! gene silencing GO:0016458 65 32 0,000 0,10101055 0,11814846 ! post-embryonic development GO:0009791 69 33 0,000 0,10399871 0,1215845 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10399871 0,12152545 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10399871 0,12146646 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10399871 0,12140752 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10399871 0,12134864 ! cell fate specification GO:0001708 52 33 0,000 0,10399871 0,12128982 ! sterol transport GO:0015918 57 33 0,000 0,10399871 0,12123106 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10399871 0,12117235 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10399871 0,1211137 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,10399871 0,12105511 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10399871 0,12099657 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,10697704 0,12440153 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10697704 0,12434143 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10697704 0,1242814 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10697704 0,12422141 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10697704 0,12416149 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,10697704 0,12410162 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10697704 0,12404182 ! mismatch repair GO:0006298 46 34 0,000 0,10697704 0,12398207 ! spermatid development GO:0007286 63 34 0,000 0,10697704 0,12392237 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10697704 0,12386274 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10697704 0,12380316 ! regulation of muscle development GO:0048634 70 35 0,000 0,10994557 0,12717743 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,10994557 0,12711632 ! negative regulation of secretion GO:0051048 63 35 0,000 0,10994557 0,12705526 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10994557 0,12699426 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,10994557 0,12693333 ! odontogenesis GO:0042476 66 35 0,000 0,10994557 0,12687245 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10994557 0,12681163 ! female gonad development GO:0008585 58 35 0,000 0,10994557 0,12675086 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,10994557 0,12669016 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,10994557 0,12662951 ! cytokine production GO:0001816 59 35 0,000 0,10994557 0,12656893 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,10994557 0,12650839 ! vesicle localization GO:0051648 64 35 0,000 0,10994557 0,12644792 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,11290434 0,12978874 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,11290434 0,12972676 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,11290434 0,12966484 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,11290434 0,12960297 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,11290434 0,12954117 ! positive regulation of cell development GO:0010720 80 36 0,000 0,11290434 0,12947942 ! regulation of proteolysis GO:0030162 72 36 0,000 0,11290434 0,12941774 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,11290434 0,12935611 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,11290434 0,12929454 ! aerobic respiration GO:0009060 55 36 0,000 0,11290434 0,12923303 ! embryonic organ development GO:0048568 57 36 0,000 0,11290434 0,12917158 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,11290434 0,12911019 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,11290434 0,12904885 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11585336 0,13235669 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11585336 0,13229387 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11585336 0,13223111 ! organic anion transport GO:0015711 68 37 0,000 0,11585336 0,13216841 ! tissue remodeling GO:0048771 76 37 0,000 0,11585336 0,13210577 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,11585336 0,13204319 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11585336 0,13198067 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,11585336 0,13191821 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11585336 0,13185581 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,11585336 0,13179347 ! glycogen metabolic process GO:0005977 61 37 0,000 0,11585336 0,13173118 ! pigment metabolic process GO:0042440 80 37 0,000 0,11585336 0,13166896 ! spermatid differentiation GO:0048515 66 37 0,000 0,11585336 0,13160679 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11879268 0,1348821 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,11879268 0,13481848 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11879268 0,13475492 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,11879268 0,13469141 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11879268 0,13462797 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,11879268 0,13456459 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,11879268 0,13450126 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,11879268 0,134438 ! lipid homeostasis GO:0055088 67 38 0,000 0,11879268 0,13437479 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11879268 0,13431164 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,11879268 0,13424856 ! glucan metabolic process GO:0044042 62 38 0,000 0,11879268 0,13418553 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,12172232 0,13743027 ! learning GO:0007612 77 39 0,000 0,12172232 0,13736581 ! ear morphogenesis GO:0042471 60 39 0,000 0,12172232 0,13730141 ! organic ether metabolic process GO:0018904 55 39 0,000 0,12172232 0,13723707 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,12172232 0,13717279 ! ion transmembrane transport GO:0034220 66 39 0,000 0,12172232 0,13710857 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,12172232 0,13704441 ! RNA modification GO:0009451 57 39 0,000 0,12172232 0,13698031 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,12172232 0,13691627 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,12464232 0,14013524 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,12464232 0,14006979 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,12464232 0,1400044 ! feeding behavior GO:0007631 59 40 0,000 0,12464232 0,13993907 ! negative regulation of binding GO:0051100 72 40 0,000 0,12464232 0,1398738 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,12464232 0,13980859 ! mesenchymal cell development GO:0014031 87 40 0,000 0,12464232 0,13974344 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,12464232 0,13967835 ! maintenance of protein location GO:0045185 91 40 0,000 0,12464232 0,13961332 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12755271 0,1428068 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12755271 0,14274038 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12755271 0,14267402 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,12755271 0,14260772 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,12755271 0,14254148 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12755271 0,14247531 ! female gamete generation GO:0007292 61 41 0,000 0,12755271 0,1424092 ! polyol metabolic process GO:0019751 66 41 0,000 0,12755271 0,14234314 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,13045352 0,14551282 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,13045352 0,1454454 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,13045352 0,14537803 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,13045352 0,14531072 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,13045352 0,14524348 ! neuron migration GO:0001764 79 42 0,000 0,13045352 0,1451763 ! regulation of protein secretion GO:0050708 71 42 0,000 0,13045352 0,14510918 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,13334478 0,14825672 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,13334478 0,14818824 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,13334478 0,14811982 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,13334478 0,14805147 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,13334478 0,14798318 ! striated muscle contraction GO:0006941 77 43 0,000 0,13334478 0,14791495 ! phagocytosis GO:0006909 90 43 0,000 0,13334478 0,14784679 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,13334478 0,14777869 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13622652 0,15090286 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13622652 0,15083341 ! male sex differentiation GO:0046661 76 44 0,000 0,13622652 0,15076403 ! biopolymer methylation GO:0043414 84 44 0,000 0,13622652 0,15069472 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,13622652 0,15062546 ! maintenance of location in cell GO:0051651 97 44 0,000 0,13622652 0,15055627 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13909878 0,15366008 ! glycolysis GO:0006096 65 45 0,000 0,13909878 0,15358956 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13909878 0,15351911 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13909878 0,15344872 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13909878 0,15337839 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13909878 0,15330813 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13909878 0,15323794 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13909878 0,15316781 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13909878 0,15309774 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13909878 0,15302773 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,14196158 0,15610583 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,14196158 0,15603451 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,14196158 0,15596327 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,14196158 0,15589208 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,14196158 0,15582096 ! response to calcium ion GO:0051592 81 47 0,000 0,14481495 0,15888042 ! endosome transport GO:0016197 108 47 0,000 0,14481495 0,15880801 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,14481495 0,15873566 ! JNK cascade GO:0007254 91 47 0,000 0,14481495 0,15866338 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,14481495 0,15859116 ! methylation GO:0032259 90 47 0,000 0,14481495 0,158519 ! protein homooligomerization GO:0051260 76 47 0,000 0,14481495 0,15844692 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14765893 0,16148518 ! cellular component disassembly GO:0022411 86 48 0,000 0,14765893 0,16141181 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,14765893 0,16133851 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14765893 0,16126527 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14765893 0,1611921 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,15049355 0,16421201 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,15049355 0,16413757 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,15049355 0,1640632 ! regulation of ion transport GO:0043269 77 49 0,000 0,15049355 0,16398889 ! peptide metabolic process GO:0006518 76 49 0,000 0,15049355 0,16391466 ! response to temperature stimulus GO:0009266 76 49 0,000 0,15049355 0,16384049 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,15049355 0,16376639 ! endocrine system development GO:0035270 104 49 0,000 0,15049355 0,16369235 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,15049355 0,16361838 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,15049355 0,16354448 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,15049355 0,16347065 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,15049355 0,16339688 ! neuromuscular process GO:0050905 99 50 0,000 0,15331883 0,16638932 ! inner ear development GO:0048839 79 50 0,000 0,15331883 0,1663143 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,15331883 0,16623935 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,15331883 0,16616447 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,15613481 0,16914019 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15613481 0,16906407 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15613481 0,16898802 ! excretion GO:0007588 83 51 0,000 0,15613481 0,16891203 ! chromatin remodeling GO:0006338 109 51 0,000 0,15613481 0,16883612 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,15613481 0,16876027 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15613481 0,16868449 ! vesicle organization GO:0016050 107 51 0,000 0,15613481 0,16860878 ! regulation of cell shape GO:0008360 125 51 0,000 0,15613481 0,16853314 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,15894152 0,17148579 ! membrane fusion GO:0006944 110 52 0,000 0,15894152 0,17140892 ! positive regulation of growth GO:0045927 90 52 0,000 0,15894152 0,17133213 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,15894152 0,1712554 ! amino acid activation GO:0043038 92 52 0,000 0,15894152 0,17117874 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,15894152 0,17110215 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,16173899 0,17403578 ! RNA catabolic process GO:0006401 93 53 0,000 0,16173899 0,17395798 ! regulation of translational initiation GO:0006446 82 53 0,000 0,16173899 0,17388026 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,16173899 0,1738026 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,16173899 0,17372501 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,16173899 0,17364748 ! cell maturation GO:0048469 100 53 0,000 0,16173899 0,17357003 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,16173899 0,17349265 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,16452725 0,17640488 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,16452725 0,1763263 ! cell recognition GO:0008037 85 54 0,000 0,16452725 0,1762478 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,16452725 0,17616936 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,16452725 0,17609099 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,16452725 0,1760127 ! chloride transport GO:0006821 90 55 0,000 0,16730632 0,17890622 ! glucose catabolic process GO:0006007 82 55 0,000 0,16730632 0,17882675 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,16730632 0,17874734 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16730632 0,178668 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,16730632 0,17858873 ! gastrulation GO:0007369 112 55 0,000 0,16730632 0,17850954 ! heart morphogenesis GO:0003007 97 55 0,000 0,16730632 0,17843041 ! nuclear export GO:0051168 97 55 0,000 0,16730632 0,17835135 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,16730632 0,17827237 ! regulation of actin filament length GO:0030832 105 56 0,000 0,17007624 0,18114362 ! sensory perception of smell GO:0007608 80 56 0,000 0,17007624 0,18106347 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,17007624 0,18098339 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,17007624 0,18090337 ! proton transport GO:0015992 94 56 0,000 0,17007624 0,18082344 ! muscle fiber development GO:0048747 112 57 0,000 0,17283704 0,18367752 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,17283704 0,18359643 ! maintenance of location GO:0051235 118 57 0,000 0,17283704 0,18351541 ! hydrogen transport GO:0006818 97 58 0,000 0,17558875 0,18635488 ! regulation of endocytosis GO:0030100 91 58 0,000 0,17558875 0,18627272 ! adult behavior GO:0030534 99 58 0,000 0,17558875 0,18619062 ! positive regulation of secretion GO:0051047 95 59 0,000 0,17833139 0,18901556 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17833139 0,18893233 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,17833139 0,18884917 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17833139 0,18876609 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,17833139 0,18868308 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,181065 0,19149116 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,181065 0,19140703 ! camera-type eye development GO:0043010 116 60 0,000 0,181065 0,19132296 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,18378961 0,19411668 ! mesoderm development GO:0007498 119 61 0,000 0,18378961 0,1940315 ! tRNA processing GO:0008033 89 61 0,000 0,18378961 0,1939464 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,18378961 0,19386137 ! ear development GO:0043583 103 62 0,000 0,18650524 0,19663962 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,18650524 0,19655348 ! gonad development GO:0008406 98 62 0,000 0,18650524 0,19646743 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,18921193 0,19923146 ! detection of external stimulus GO:0009581 91 63 0,000 0,18921193 0,19914431 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,18921193 0,19905723 ! cell redox homeostasis GO:0045454 102 64 0,000 0,1919097 0,20180714 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,1919097 0,20171897 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,1919097 0,20163089 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,1919097 0,20154288 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,19459858 0,20427757 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,19459858 0,20418848 ! germ cell development GO:0007281 118 65 0,000 0,19459858 0,20409947 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,19727861 0,20682019 ! actin filament organization GO:0007015 148 66 0,000 0,19727861 0,20673011 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19727861 0,20664011 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19727861 0,20655019 ! secondary metabolic process GO:0019748 116 66 0,000 0,19727861 0,20646034 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,1999498 0,20916488 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,1999498 0,20907398 ! activation of MAPK activity GO:0000187 115 67 0,000 0,1999498 0,20898316 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,1999498 0,20889241 ! hexose catabolic process GO:0019320 104 67 0,000 0,1999498 0,20880175 ! adaptive immune response GO:0002250 119 67 0,000 0,1999498 0,20871116 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,1999498 0,20862065 ! amino acid transport GO:0006865 125 68 0,000 0,2026122 0,21130687 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,2026122 0,21121532 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,2026122 0,21112384 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,2026122 0,21103245 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,2026122 0,21094113 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,20526582 0,21361141 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,20526582 0,21351906 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,20526582 0,21342678 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,20526582 0,21333459 ! antigen processing and presentation GO:0019882 104 69 0,000 0,20526582 0,21324248 ! amine catabolic process GO:0009310 117 71 0,000 0,21054687 0,21863435 ! reproductive structure development GO:0048608 113 71 0,000 0,21054687 0,21854003 ! humoral immune response GO:0006959 109 71 0,000 0,21054687 0,21844579 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,21054687 0,21835163 ! acute inflammatory response GO:0002526 113 72 0,000 0,21317436 0,22098126 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,21317436 0,22088609 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,21317436 0,220791 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,21579318 0,22340723 ! axon guidance GO:0007411 139 73 0,000 0,21579318 0,22331114 ! fertilization GO:0009566 90 73 0,000 0,21579318 0,22321513 ! transition metal ion transport GO:0000041 126 74 0,000 0,21840337 0,22581801 ! neurotransmitter transport GO:0006836 123 74 0,000 0,21840337 0,22572101 ! exocytosis GO:0006887 133 74 0,000 0,21840337 0,2256241 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,21840337 0,22552726 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,21840337 0,22543051 ! eye development GO:0001654 143 74 0,000 0,21840337 0,22533384 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,22100497 0,22792025 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,22100497 0,2278226 ! rhythmic process GO:0048511 128 75 0,000 0,22100497 0,22772503 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,22359799 0,23029827 ! defense response to bacterium GO:0042742 89 76 0,000 0,22359799 0,23019973 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,22359799 0,23010127 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,22359799 0,23000289 ! regulation of catabolic process GO:0009894 161 76 0,000 0,22359799 0,2299046 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,22618246 0,23246262 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,22618246 0,23236337 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,22618246 0,23226419 ! blood coagulation GO:0007596 146 78 0,000 0,22875842 0,2348092 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,22875842 0,23470906 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,23132589 0,23724215 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,23132589 0,23714107 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,23132589 0,23704007 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,23132589 0,23693916 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,23132589 0,23683833 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,23388489 0,23935647 ! response to metal ion GO:0010038 140 80 0,000 0,23388489 0,2392547 ! inorganic anion transport GO:0015698 138 80 0,000 0,23388489 0,23915302 ! digestion GO:0007586 112 81 0,000 0,23643546 0,24165834 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,23643546 0,24155572 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,23643546 0,24145319 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,23897763 0,24394577 ! response to nutrient GO:0007584 125 82 0,000 0,23897763 0,24384231 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,23897763 0,24373895 ! regulation of lyase activity GO:0051339 160 83 0,000 0,24151141 0,24621884 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,24403685 0,24868812 ! hemostasis GO:0007599 158 84 0,000 0,24403685 0,24858283 ! regulation of ligase activity GO:0051340 142 84 0,000 0,24403685 0,24847764 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,24403685 0,24837253 ! response to unfolded protein GO:0006986 131 85 0,000 0,24655396 0,25082825 ! nucleosome assembly GO:0006334 122 85 0,000 0,24655396 0,25072224 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,24655396 0,25061631 ! amine biosynthetic process GO:0009309 138 86 0,000 0,24906277 0,25305955 ! response to inorganic substance GO:0010035 153 86 0,000 0,24906277 0,25295273 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,24906277 0,252846 ! chromatin assembly GO:0031497 124 86 0,000 0,24906277 0,25273936 ! alcohol catabolic process GO:0046164 130 86 0,000 0,24906277 0,25263281 ! amine transport GO:0015837 155 86 0,000 0,24906277 0,25252634 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,25156331 0,25495422 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,25156331 0,25484687 ! regulation of protein transport GO:0051223 154 87 0,000 0,25156331 0,25473961 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,2540556 0,25715515 ! regulation of neurological system process GO:0031644 148 88 0,000 0,2540556 0,25704701 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2540556 0,25693896 ! cellular defense response GO:0006968 114 89 0,000 0,25653968 0,25934222 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,25653968 0,2592333 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,25901557 0,2616253 ! sex differentiation GO:0007548 145 90 0,000 0,25901557 0,26151551 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,25901557 0,26140582 ! response to protein stimulus GO:0051789 149 91 0,000 0,2614833 0,26378567 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,2614833 0,26367511 ! nucleosome organization GO:0034728 138 92 0,000 0,26394289 0,26604382 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,26394289 0,26593241 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,26639437 0,26829002 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,26639437 0,26817777 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,26639437 0,2680656 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,26883777 0,27041123 ! forebrain development GO:0030900 188 95 0,000 0,27127311 0,2727468 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,27127311 0,27263287 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,27370042 0,2749575 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,27370042 0,27484274 ! positive regulation of immune response GO:0050778 156 96 0,000 0,27370042 0,27472808 ! detection of stimulus GO:0051606 151 96 0,000 0,27370042 0,27461351 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,27611972 0,27692541 ! protein ubiquitination GO:0016567 217 97 0,000 0,27611972 0,27681002 ! hormone metabolic process GO:0042445 157 97 0,000 0,27611972 0,27669473 ! regulation of protein localization GO:0032880 176 97 0,000 0,27611972 0,27657954 ! response to virus GO:0009615 160 98 0,000 0,27853105 0,27887878 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,27853105 0,27876277 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,28093443 0,28105124 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,28093443 0,28093443