pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/562-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 156 86 8,000 6,355E-09 1,462E-05 ! interphase GO:0051325 159 88 8,000 7,807E-09 8,978E-06 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 6,000 1,406E-08 1,078E-05 ! regulation of bone remodeling GO:0046850 90 53 6,000 6,36E-08 3,657E-05 ! regulation of tissue remodeling GO:0034103 91 54 6,000 7,267E-08 3,343E-05 ! cell cycle arrest GO:0007050 150 86 7,000 1,16E-07 4,448E-05 ! regulation of ossification GO:0030278 71 46 5,000 6,253E-07 2,054E-04 ! morphogenesis of a branching structure GO:0001763 86 49 5,000 9,182E-07 2,64E-04 ! positive regulation of cell migration GO:0030335 92 51 5,000 1,17E-06 2,989E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 3,000 1,874E-06 4,31E-04 GO:0060675|ureteric bud morphogenesis, ! C21-steroid hormone biosynthetic process GO:0006700 15 14 3,000 1,874E-06 3,918E-04 ! positive regulation of cell motion GO:0051272 99 56 5,000 2,052E-06 3,932E-04 ! angiogenesis GO:0001525 149 95 6,000 3,61E-06 6,388E-04 ! negative regulation of cell growth GO:0030308 106 62 5,000 3,758E-06 6,175E-04 ! proximal/distal pattern formation GO:0009954 25 17 3,000 4,386E-06 6,725E-04 ! negative regulation of cell size GO:0045792 108 64 5,000 4,534E-06 6,517E-04 ! apoptotic mitochondrial changes GO:0008637 29 18 3,000 5,61E-06 7,59E-04 ! ER overload response GO:0006983 7 6 2,000 5,908E-06 7,549E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 2,000 5,908E-06 7,151E-04 ! positive regulation of ossification GO:0045778 30 19 3,000 7,069E-06 8,129E-04 ! C21-steroid hormone metabolic process GO:0008207 23 19 3,000 7,069E-06 7,742E-04 ! sex determination GO:0007530 29 19 3,000 7,069E-06 7,39E-04 ! branching morphogenesis of a tube GO:0048754 72 42 4,000 8,965E-06 8,965E-04 ! positive regulation of bone remodeling GO:0046852 33 21 3,000 1,08E-05 1,035E-03 GO:0034105|positive regulation of tissue remodeling, ! response to endoplasmic reticulum stress GO:0034976 25 21 3,000 1,08E-05 9,938E-04 ! negative regulation of growth GO:0045926 123 75 5,000 1,146E-05 1,014E-03 ! regulation of cell-matrix adhesion GO:0001952 51 22 3,000 1,313E-05 1,119E-03 GO:0010810|regulation of cell-substrate adhesion, ! ureteric bud development GO:0001657 32 22 3,000 1,313E-05 1,079E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 3,000 1,582E-05 1,254E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 1,638E-05 1,256E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 2,000 1,638E-05 1,215E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 3,000 1,888E-05 1,357E-03 ! regulation of osteoblast differentiation GO:0045667 37 24 3,000 1,888E-05 1,316E-03 ! positive regulation of growth GO:0045927 67 50 4,000 2,139E-05 1,447E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 3,475E-05 2,284E-03 ! hair follicle morphogenesis GO:0031069 17 10 2,000 3,475E-05 2,22E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 2,000 3,475E-05 2,16E-03 ! focal adhesion formation GO:0048041 24 11 2,000 4,755E-05 2,878E-03 ! digestive tract morphogenesis GO:0048546 15 11 2,000 4,755E-05 2,804E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of homeostatic process GO:0032844 105 60 4,000 5,225E-05 3,004E-03 ! metanephros development GO:0001656 58 31 3,000 5,39E-05 3,024E-03 ! cell-matrix adhesion GO:0007160 114 61 4,000 5,661E-05 3,1E-03 ! autonomic nervous system development GO:0048483 23 12 2,000 6,309E-05 3,374E-03 ! gland morphogenesis GO:0022612 23 12 2,000 6,309E-05 3,298E-03 ! positive regulation of cell development GO:0010720 54 33 3,000 6,938E-05 3,546E-03 ! hormone biosynthetic process GO:0042446 45 33 3,000 6,938E-05 3,469E-03 ! cell-substrate adhesion GO:0031589 121 66 4,000 8,279E-05 4,051E-03 ! response to reactive oxygen species GO:0000302 55 36 3,000 9,832E-05 4,711E-03 ! negative regulation of bone remodeling GO:0046851 26 14 2,000 1,034E-04 4,851E-03 ! epidermis morphogenesis GO:0048730 29 14 2,000 1,034E-04 4,754E-03 ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,034E-04 4,661E-03 ! epithelial to mesenchymal transition GO:0001837 22 14 2,000 1,034E-04 4,571E-03 ! steroid biosynthetic process GO:0006694 94 71 4,000 1,174E-04 5,095E-03 ! mesenchymal cell development GO:0014031 64 38 3,000 1,219E-04 5,193E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! response to hypoxia GO:0001666 132 72 4,000 1,255E-04 5,248E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 1,286E-04 5,28E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 1,286E-04 5,187E-03 ! negative regulation of tissue remodeling GO:0034104 27 15 2,000 1,286E-04 5,098E-03 ! tube morphogenesis GO:0035239 118 73 4,000 1,34E-04 5,224E-03 ! response to oxygen levels GO:0070482 137 74 4,000 1,43E-04 5,48E-03 ! cellular response to unfolded protein GO:0034620 19 16 2,000 1,574E-04 5,937E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! G1 phase GO:0051318 27 16 2,000 1,574E-04 5,841E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 1,902E-04 6,945E-03 ! cell-substrate junction assembly GO:0007044 39 17 2,000 1,902E-04 6,837E-03 ! peptidyl-serine modification GO:0018209 27 17 2,000 1,902E-04 6,732E-03 ! negative regulation of homeostatic process GO:0032845 28 17 2,000 1,902E-04 6,63E-03 ! epithelial tube morphogenesis GO:0060562 65 43 3,000 1,986E-04 6,819E-03 ! gut development GO:0048565 26 18 2,000 2,272E-04 7,684E-03 ! negative regulation of T cell activation GO:0050868 25 18 2,000 2,272E-04 7,572E-03 ! regulation of cell adhesion GO:0030155 159 83 4,000 2,455E-04 8,067E-03 ! response to UV GO:0009411 75 46 3,000 2,586E-04 8,377E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 2,684E-04 8,575E-03 ! response to alkaloid GO:0043279 32 19 2,000 2,684E-04 8,458E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 2,684E-04 8,343E-03 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 2,684E-04 8,232E-03 ! apoptotic nuclear changes GO:0030262 24 19 2,000 2,684E-04 8,124E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 2,684E-04 8,018E-03 ! negative regulation of immune system process GO:0002683 73 47 3,000 2,812E-04 8,291E-03 ! positive regulation of osteoblast differentiation GO:0045669 33 20 2,000 3,143E-04 9,149E-03 ! integrin-mediated signaling pathway GO:0007229 81 49 3,000 3,306E-04 9,503E-03 ! cartilage development GO:0051216 70 49 3,000 3,306E-04 9,386E-03 ! reproductive developmental process GO:0003006 127 89 4,000 3,399E-04 9,534E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 3,648E-04 0,01011005 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 3,648E-04 9,99E-03 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 3,648E-04 9,872E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 3,859E-04 0,01031925 ! cell fate commitment GO:0045165 141 92 4,000 3,963E-04 0,01047722 ! aging GO:0007568 79 52 3,000 4,158E-04 0,01086859 ! peptidyl-amino acid modification GO:0018193 147 93 4,000 4,166E-04 0,01076596 ! regulation of fibroblast proliferation GO:0048145 35 22 2,000 4,204E-04 0,01074288 ! molting cycle process GO:0022404 40 22 2,000 4,204E-04 0,01062483 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! sleep GO:0030431 11 5 1,000 4,458E-04 0,01114491 ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,458E-04 0,01102507 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 4,458E-04 0,01090778 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 4,458E-04 0,01079297 ! rhythmic behavior GO:0007622 12 5 1,000 4,458E-04 0,01068054 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 4,458E-04 0,01057043 ! microvillus organization GO:0032528 7 5 1,000 4,458E-04 0,01046257 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 1,000 4,458E-04 0,01035689 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 1,000 4,458E-04 0,01025332 ! peptidyl-threonine phosphorylation GO:0018107 14 5 1,000 4,458E-04 0,0101518 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 4,458E-04 0,01005227 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 1,000 4,458E-04 9,955E-03 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! positive regulation of organ growth GO:0046622 6 5 1,000 4,458E-04 9,859E-03 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 4,458E-04 9,765E-03 ! enteric nervous system development GO:0048484 8 5 1,000 4,458E-04 9,673E-03 ! muscle cell proliferation GO:0033002 8 5 1,000 4,458E-04 9,583E-03 ! regulation of hair follicle development GO:0051797 9 5 1,000 4,458E-04 9,494E-03 GO:0042634|regulation of hair cycle, ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 4,458E-04 9,407E-03 ! glial cell migration GO:0008347 10 5 1,000 4,458E-04 9,321E-03 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 4,458E-04 9,237E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 4,458E-04 9,155E-03 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 4,458E-04 9,074E-03 ! skeletal system morphogenesis GO:0048705 78 53 3,000 4,475E-04 9,028E-03 ! kidney development GO:0001822 90 53 3,000 4,475E-04 8,949E-03 ! regulation of binding GO:0051098 151 95 4,000 4,595E-04 9,111E-03 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 4,811E-04 9,457E-03 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 4,811E-04 9,377E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 5,912E-04 0,01142693 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 6,186E-04 0,01185718 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 6,186E-04 0,01175919 ! negative regulation of kinase activity GO:0033673 100 58 3,000 6,317E-04 0,01190969 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 6,657E-04 0,01244881 ! neuron adhesion GO:0007158 9 6 1,000 6,657E-04 0,01234842 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 6,657E-04 0,01224963 ! mRNA stabilization GO:0048255 15 6 1,000 6,657E-04 0,01215241 GO:0043489|RNA stabilization, ! regulation of odontogenesis GO:0042481 8 6 1,000 6,657E-04 0,01205672 ! pigment granule organization GO:0048753 11 6 1,000 6,657E-04 0,01196253 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 6,657E-04 0,0118698 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 6,657E-04 0,01177849 ! negative regulation of T cell differentiation GO:0045581 7 6 1,000 6,657E-04 0,01168858 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 6,657E-04 0,01160003 ! salivary gland morphogenesis GO:0007435 11 6 1,000 6,657E-04 0,01151281 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 6,657E-04 0,01142689 GO:0045625|regulation of T-helper 1 cell differentiation, ! negative regulation of B cell activation GO:0050869 9 6 1,000 6,657E-04 0,01134225 ! lung development GO:0030324 94 59 3,000 6,742E-04 0,01140147 ! embryonic limb morphogenesis GO:0030326 86 60 3,000 7,186E-04 0,01206404 GO:0035113|embryonic appendage morphogenesis, ! urogenital system development GO:0001655 101 61 3,000 7,651E-04 0,01275087 ! negative regulation of transferase activity GO:0051348 105 61 3,000 7,651E-04 0,01265914 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 7,79E-04 0,01279865 ! negative regulation of transcription regulator activity GO:0090048 47 27 2,000 7,79E-04 0,01270788 GO:0043433|negative regulation of transcription factor activity, ! cellular hormone metabolic process GO:0034754 87 62 3,000 8,136E-04 0,01317788 ! respiratory tube development GO:0030323 99 62 3,000 8,136E-04 0,01308573 ! regulation of transcription factor activity GO:0051090 97 63 3,000 8,643E-04 0,01380421 GO:0090046|regulation of transcription regulator activity, ! cell junction assembly GO:0034329 56 28 2,000 8,683E-04 0,01377237 ! positive regulation of multicellular organism growth GO:0040018 38 28 2,000 8,683E-04 0,01367804 ! regulation of B cell activation GO:0050864 42 28 2,000 8,683E-04 0,01358499 ! appendage morphogenesis GO:0035107 93 64 3,000 9,171E-04 0,01425257 GO:0035108|limb morphogenesis, ! respiratory system development GO:0060541 100 64 3,000 9,171E-04 0,01415691 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 9,279E-04 0,01422814 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 9,279E-04 0,01413391 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 9,279E-04 0,01404093 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 9,279E-04 0,01394916 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 9,279E-04 0,01385858 ! T-helper 1 type immune response GO:0042088 11 7 1,000 9,279E-04 0,01376917 ! regulation of pigmentation during development GO:0048070 15 7 1,000 9,279E-04 0,0136809 ! organ growth GO:0035265 11 7 1,000 9,279E-04 0,01359376 ! behavioral fear response GO:0001662 13 7 1,000 9,279E-04 0,01350773 GO:0002209|behavioral defense response, ! response to UV-B GO:0010224 11 7 1,000 9,279E-04 0,01342277 ! B cell lineage commitment GO:0002326 17 7 1,000 9,279E-04 0,01333888 ! T cell lineage commitment GO:0002360 12 7 1,000 9,279E-04 0,01325603 ! peptidyl-threonine modification GO:0018210 18 7 1,000 9,279E-04 0,0131742 ! positive regulation of epidermis development GO:0045684 11 7 1,000 9,279E-04 0,01309338 ! dopamine biosynthetic process GO:0042416 15 7 1,000 9,279E-04 0,01301354 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 9,279E-04 0,01293467 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 1,000 9,279E-04 0,01285675 ! response to hydrogen peroxide GO:0042542 42 29 2,000 9,637E-04 0,01327249 ! appendage development GO:0048736 94 65 3,000 9,722E-04 0,01331011 GO:0060173|limb development, ! hindbrain development GO:0030902 45 30 2,000 1,066E-03 0,01450132 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,066E-03 0,01441602 ! response to drug GO:0042493 108 69 3,000 1,216E-03 0,01635536 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,232E-03 0,01647134 ! induction of positive chemotaxis GO:0050930 14 8 1,000 1,232E-03 0,01637613 ! succinate metabolic process GO:0006105 14 8 1,000 1,232E-03 0,01628202 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,232E-03 0,01618898 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,232E-03 0,01609699 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,232E-03 0,01600605 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,232E-03 0,01591613 ! melanin metabolic process GO:0006582 12 8 1,000 1,232E-03 0,01582721 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 1,232E-03 0,01573928 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,232E-03 0,01565233 ! regulation of smoothened signaling pathway GO:0008589 13 8 1,000 1,232E-03 0,01556632 ! regulation of gliogenesis GO:0014013 20 8 1,000 1,232E-03 0,01548126 GO:0045685|regulation of glial cell differentiation, ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,232E-03 0,01539712 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 1,232E-03 0,0153139 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,232E-03 0,01523156 ! induction of an organ GO:0001759 11 8 1,000 1,232E-03 0,01515011 ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 1,232E-03 0,01506953 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,232E-03 0,01498979 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,232E-03 0,0149109 ! regulation of protein stability GO:0031647 48 32 2,000 1,289E-03 0,01552223 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 1,353E-03 0,01620326 ! cell junction organization GO:0034330 63 33 2,000 1,411E-03 0,01681484 ! nucleus organization GO:0006997 49 33 2,000 1,411E-03 0,01672817 ! negative regulation of DNA binding GO:0043392 54 33 2,000 1,411E-03 0,01664238 ! mitochondrion organization GO:0007005 104 73 3,000 1,5E-03 0,01759772 ! embryonic organ development GO:0048568 45 34 2,000 1,54E-03 0,01797925 ! SMAD protein nuclear translocation GO:0007184 15 9 1,000 1,577E-03 0,01831543 ! lung alveolus development GO:0048286 17 9 1,000 1,577E-03 0,01822339 ! T cell selection GO:0045058 18 9 1,000 1,577E-03 0,01813227 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,577E-03 0,01804206 GO:0006600|creatine metabolic process, ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 1,577E-03 0,01795275 ! response to amine stimulus GO:0014075 13 9 1,000 1,577E-03 0,01786431 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 1,000 1,577E-03 0,01777674 ! oocyte differentiation GO:0009994 12 9 1,000 1,577E-03 0,01769002 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 1,000 1,577E-03 0,01760415 ! spleen development GO:0048536 15 9 1,000 1,577E-03 0,0175191 ! negative regulation of BMP signaling pathway GO:0030514 13 9 1,000 1,577E-03 0,01743488 ! response to nicotine GO:0035094 16 9 1,000 1,577E-03 0,01735146 ! regulation of ligase activity GO:0051340 114 75 3,000 1,657E-03 0,01815278 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 1,676E-03 0,01827025 ! negative regulation of binding GO:0051100 58 36 2,000 1,82E-03 0,0197402 ! regulation of DNA binding GO:0051101 119 77 3,000 1,826E-03 0,01972181 ! regulation of phosphatase activity GO:0010921 21 10 1,000 1,962E-03 0,02108919 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 1,962E-03 0,0209911 ! blood vessel remodeling GO:0001974 21 10 1,000 1,962E-03 0,02089392 ! positive regulation of heart contraction GO:0045823 14 10 1,000 1,962E-03 0,02079763 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 1,962E-03 0,02070223 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,962E-03 0,0206077 ! B cell proliferation GO:0042100 14 10 1,000 1,962E-03 0,02051403 ! phagocytosis, engulfment GO:0006911 20 10 1,000 1,962E-03 0,0204212 ! fear response GO:0042596 16 10 1,000 1,962E-03 0,02032922 ! negative regulation of ossification GO:0030279 19 10 1,000 1,962E-03 0,02023805 ! regulation of bone resorption GO:0045124 24 10 1,000 1,962E-03 0,0201477 ! alpha-beta T cell activation GO:0046631 16 10 1,000 1,962E-03 0,02005816 ! regulation of organ growth GO:0046620 11 10 1,000 1,962E-03 0,01996941 ! cranial nerve development GO:0021545 12 10 1,000 1,962E-03 0,01988144 ! DNA methylation GO:0006306 15 10 1,000 1,962E-03 0,01979424 GO:0006305|DNA alkylation, ! salivary gland development GO:0007431 22 10 1,000 1,962E-03 0,0197078 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,962E-03 0,01962211 ! embryonic gut development GO:0048566 11 10 1,000 1,962E-03 0,01953717 ! cardiac cell differentiation GO:0035051 16 10 1,000 1,962E-03 0,01945296 ! developmental induction GO:0031128 13 10 1,000 1,962E-03 0,01936947 GO:0045168|cell-cell signaling involved in cell fate specification, ! gliogenesis GO:0042063 71 38 2,000 2,129E-03 0,02092451 ! pigmentation GO:0043473 74 38 2,000 2,129E-03 0,02083547 ! response to protein stimulus GO:0051789 111 81 3,000 2,2E-03 0,02143626 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 2,295E-03 0,02227197 ! cell growth GO:0016049 61 39 2,000 2,295E-03 0,02217839 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 2,388E-03 0,02297779 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 1,000 2,388E-03 0,02288205 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 1,000 2,388E-03 0,0227871 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 2,388E-03 0,02269294 ! chondrocyte differentiation GO:0002062 17 11 1,000 2,388E-03 0,02259955 ! T cell homeostasis GO:0043029 20 11 1,000 2,388E-03 0,02250693 ! regulation of leukocyte migration GO:0002685 24 11 1,000 2,388E-03 0,02241506 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 1,000 2,388E-03 0,02232395 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 2,388E-03 0,02223357 GO:0042130|negative regulation of T cell proliferation, ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 2,469E-03 0,02289749 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 2,469E-03 0,02280554 ! positive regulation of protein transport GO:0051222 55 40 2,000 2,469E-03 0,02271431 ! anterior/posterior pattern formation GO:0009952 124 85 3,000 2,622E-03 0,0240283 ! regulation of protein localization GO:0032880 132 85 3,000 2,622E-03 0,02393295 ! regulation of T cell differentiation GO:0045580 59 41 2,000 2,651E-03 0,02409874 ! mitochondrial transport GO:0006839 60 42 2,000 2,841E-03 0,02572418 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 2,841E-03 0,0256233 ! cellular component disassembly GO:0022411 64 42 2,000 2,841E-03 0,02552321 ! cartilage condensation GO:0001502 18 12 1,000 2,853E-03 0,02552922 ! positive regulation of cell growth GO:0030307 16 12 1,000 2,853E-03 0,02543027 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 2,853E-03 0,02533208 ! histone acetylation GO:0016573 23 12 1,000 2,853E-03 0,02523465 ! peptidyl-lysine modification GO:0018205 18 12 1,000 2,853E-03 0,02513797 ! response to gamma radiation GO:0010332 20 12 1,000 2,853E-03 0,02504202 ! regulation of epidermis development GO:0045682 17 12 1,000 2,853E-03 0,0249468 ! regulation of mRNA stability GO:0043488 27 12 1,000 2,853E-03 0,02485231 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 2,853E-03 0,02475853 ! activation of caspase activity GO:0006919 65 43 2,000 3,039E-03 0,02627716 ! hormone metabolic process GO:0042445 121 90 3,000 3,225E-03 0,02778067 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 3,245E-03 0,02785293 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 3,356E-03 0,02869811 ! exocrine system development GO:0035272 27 13 1,000 3,356E-03 0,02859182 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 3,356E-03 0,02848632 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 3,356E-03 0,02838159 ! cellular pigmentation GO:0033059 24 13 1,000 3,356E-03 0,02827763 ! positive regulation of bone mineralization GO:0030501 19 13 1,000 3,356E-03 0,02817443 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 3,356E-03 0,02807197 ! regulation of RNA stability GO:0043487 28 13 1,000 3,356E-03 0,02797026 ! lymphocyte homeostasis GO:0002260 24 13 1,000 3,356E-03 0,02786929 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 1,000 3,356E-03 0,02776904 ! positive regulation of cell cycle GO:0045787 77 45 2,000 3,46E-03 0,0285261 ! response to oxidative stress GO:0006979 141 94 3,000 3,77E-03 0,03097133 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 3,899E-03 0,03191034 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 3,899E-03 0,03179718 ! heterophilic cell adhesion GO:0007157 29 14 1,000 3,899E-03 0,03168482 ! positive regulation of biomineral formation GO:0070169 20 14 1,000 3,899E-03 0,03157326 ! T cell differentiation in the thymus GO:0033077 27 14 1,000 3,899E-03 0,03146247 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 3,899E-03 0,03135247 ! regulation of T-helper 2 type immune response GO:0002828 21 14 1,000 3,899E-03 0,03124322 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 3,899E-03 0,03113474 ! catecholamine biosynthetic process GO:0042423 23 14 1,000 3,899E-03 0,03102701 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 3,916E-03 0,03105563 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of neuron apoptosis GO:0043523 77 47 2,000 3,916E-03 0,03094891 ! response to light stimulus GO:0009416 153 96 3,000 4,065E-03 0,03202083 ! positive regulation of caspase activity GO:0043280 72 48 2,000 4,156E-03 0,03262714 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 65 48 2,000 4,156E-03 0,03251616 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 4,156E-03 0,03240593 ! regulation of intracellular transport GO:0032386 78 49 2,000 4,406E-03 0,03423524 ! positive regulation of cell size GO:0045793 20 15 1,000 4,479E-03 0,03468291 ! metencephalon development GO:0022037 19 15 1,000 4,479E-03 0,03456652 ! regulation of survival gene product expression GO:0045884 20 15 1,000 4,479E-03 0,03445092 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 4,479E-03 0,03433608 ! dopamine metabolic process GO:0042417 30 15 1,000 4,479E-03 0,03422201 ! regulation of BMP signaling pathway GO:0030510 21 15 1,000 4,479E-03 0,03410869 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 4,479E-03 0,03399612 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 4,479E-03 0,03388429 ! defense response to virus GO:0051607 27 15 1,000 4,479E-03 0,03377319 ! ear development GO:0043583 72 50 2,000 4,664E-03 0,03505877 ! regulation of multicellular organism growth GO:0040014 65 50 2,000 4,664E-03 0,03494457 ! protein amino acid acetylation GO:0006473 28 16 1,000 5,096E-03 0,03805402 ! patterning of blood vessels GO:0001569 24 16 1,000 5,096E-03 0,03793087 ! regulation of protein binding GO:0043393 27 16 1,000 5,096E-03 0,03780851 ! regulation of dephosphorylation GO:0035303 33 16 1,000 5,096E-03 0,03768694 ! negative regulation of immune response GO:0050777 28 16 1,000 5,096E-03 0,03756615 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 5,096E-03 0,03744613 ! oogenesis GO:0048477 23 16 1,000 5,096E-03 0,03732687 ! neutrophil chemotaxis GO:0030593 21 16 1,000 5,096E-03 0,03720837 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 5,096E-03 0,03709063 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 1,000 5,096E-03 0,03697362 ! nerve development GO:0021675 18 16 1,000 5,096E-03 0,03685735 ! regulation of viral genome replication GO:0045069 24 17 1,000 5,75E-03 0,04145783 ! synaptogenesis GO:0007416 24 17 1,000 5,75E-03 0,04132827 ! DNA catabolic process GO:0006308 67 54 2,000 5,789E-03 0,04147713 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 6,44E-03 0,04600269 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 1,000 6,44E-03 0,04586027 ! somitogenesis GO:0001756 24 18 1,000 6,44E-03 0,04571872 ! developmental maturation GO:0021700 75 57 2,000 6,73E-03 0,04762527 ! regeneration GO:0031099 32 19 1,000 7,166E-03 0,0505611 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 7,166E-03 0,05040648 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 7,166E-03 0,0502528 ! renal system process GO:0003014 35 19 1,000 7,166E-03 0,05010006 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 1,000 7,166E-03 0,04994824 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 7,166E-03 0,04979734 ! embryonic organ morphogenesis GO:0048562 23 19 1,000 7,166E-03 0,04964735 ! response to ethanol GO:0045471 37 20 1,000 7,928E-03 0,05475688 ! multicellular organismal response to stress GO:0033555 32 20 1,000 7,928E-03 0,05459294 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 7,928E-03 0,05442998 ! DNA modification GO:0006304 28 20 1,000 7,928E-03 0,05426798 ! positive regulation of locomotion GO:0040017 35 20 1,000 7,928E-03 0,05410695 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 1,000 7,928E-03 0,05394687 ! positive regulation of B cell activation GO:0050871 31 20 1,000 7,928E-03 0,05378774 ! homeostasis of number of cells GO:0048872 84 61 2,000 8,118E-03 0,05491589 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 8,118E-03 0,05475485 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 8,489E-03 0,05709254 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 8,724E-03 0,05849879 ! protein amino acid acylation GO:0043543 37 21 1,000 8,724E-03 0,05832874 ! regulation of chemotaxis GO:0050920 36 21 1,000 8,724E-03 0,05815967 ! ovarian follicle development GO:0001541 30 21 1,000 8,724E-03 0,05799158 ! cell aging GO:0007569 32 21 1,000 8,724E-03 0,05782445 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 8,724E-03 0,05765829 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 8,724E-03 0,05749308 ! cholesterol biosynthetic process GO:0006695 29 21 1,000 8,724E-03 0,05732881 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 8,724E-03 0,05716548 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 8,724E-03 0,05700308 ! regulation of bone mineralization GO:0030500 29 21 1,000 8,724E-03 0,0568416 ! response to cytokine stimulus GO:0034097 47 21 1,000 8,724E-03 0,05668103 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 8,871E-03 0,05747195 ! cell cycle checkpoint GO:0000075 108 64 2,000 9,262E-03 0,05983765 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 9,262E-03 0,05967004 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 9,554E-03 0,06138242 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 9,554E-03 0,06121144 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 9,554E-03 0,06104141 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 9,554E-03 0,06087232 ! vasculogenesis GO:0001570 33 22 1,000 9,554E-03 0,06070417 ! regulation of behavior GO:0050795 38 22 1,000 9,554E-03 0,06053694 ! leukocyte homeostasis GO:0001776 33 22 1,000 9,554E-03 0,06037063 ! regulation of caspase activity GO:0043281 97 65 2,000 9,663E-03 0,06088975 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 9,663E-03 0,06072338 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 2,000 9,663E-03 0,06055792 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 0,01041843 0,06511517 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01041843 0,0649387 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 0,01041843 0,06476319 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01041843 0,06458863 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 0,01041843 0,064415 ! osteoblast differentiation GO:0001649 40 23 1,000 0,01041843 0,06424231 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,01041843 0,06407054 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,01041843 0,06389968 ! regulation of biomineral formation GO:0070167 31 23 1,000 0,01041843 0,06372974 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,01041843 0,06356069 ! liver development GO:0001889 40 23 1,000 0,01041843 0,06339254 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01049521 0,06369124 ! intracellular protein transmembrane transport GO:0065002 102 68 2,000 0,01092646 0,06613384 ! rhythmic process GO:0048511 105 68 2,000 0,01092646 0,06596026 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 0,01131582 0,06813191 ! fat cell differentiation GO:0045444 37 24 1,000 0,01131582 0,06795402 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01131582 0,06777706 ! response to toxin GO:0009636 38 24 1,000 0,01131582 0,06760101 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01131582 0,06742588 ! glutathione metabolic process GO:0006749 29 24 1,000 0,01131582 0,06725165 ! activation of protein kinase activity GO:0032147 102 69 2,000 0,01136785 0,06738671 ! positive regulation of ligase activity GO:0051351 99 69 2,000 0,01136785 0,06721348 ! response to metal ion GO:0010038 103 70 2,000 0,0118194 0,06970418 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 2,000 0,0118194 0,06952591 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 0,0118194 0,06934854 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 1,000 0,01224601 0,07166877 ! male gonad development GO:0008584 33 25 1,000 0,01224601 0,07148687 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01224601 0,07130589 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01224601 0,07112583 ! positive regulation of MAPKKK cascade GO:0043410 36 25 1,000 0,01224601 0,07094667 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 0,01224601 0,07076841 ! leukocyte proliferation GO:0070661 39 25 1,000 0,01224601 0,07059105 GO:0032943|mononuclear cell proliferation, ! regulation of peptidase activity GO:0052547 106 72 2,000 0,01275319 0,07333084 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 0,01275319 0,07314797 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,01320852 0,07557114 ! circadian rhythm GO:0007623 42 26 1,000 0,01320852 0,07538362 ! post-embryonic development GO:0009791 42 26 1,000 0,01320852 0,07519703 ! protein import into nucleus GO:0006606 118 74 2,000 0,01372809 0,077962 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 0,01372809 0,07776997 ! catechol metabolic process GO:0009712 43 27 1,000 0,01420288 0,08026197 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to ionizing radiation GO:0010212 47 27 1,000 0,01420288 0,08006525 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,01420288 0,07986949 ! response to inorganic substance GO:0010035 115 75 2,000 0,01423103 0,07983263 ! response to nutrient GO:0007584 104 75 2,000 0,01423103 0,07963839 ! nuclear import GO:0051170 121 75 2,000 0,01423103 0,0794451 ! response to unfolded protein GO:0006986 99 76 2,000 0,01474434 0,08211136 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 0,01474434 0,08191303 ! regulation of protein transport GO:0051223 114 76 2,000 0,01474434 0,08171565 GO:0070201|regulation of establishment of protein localization, ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 0,01522862 0,08419669 ! phenol metabolic process GO:0018958 44 28 1,000 0,01522862 0,08399478 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,01522862 0,08379384 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01522862 0,08359385 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,01522862 0,08339482 ! sterol biosynthetic process GO:0016126 40 28 1,000 0,01522862 0,08319673 ! BMP signaling pathway GO:0030509 40 28 1,000 0,01522862 0,08299958 ! gland development GO:0048732 148 77 2,000 0,01526804 0,08301774 ! one-carbon metabolic process GO:0006730 110 77 2,000 0,01526804 0,08282194 ! positive regulation of protein modification process GO:0031401 107 78 2,000 0,01580216 0,08551756 ! ovulation cycle process GO:0022602 41 29 1,000 0,01628528 0,08792522 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01628528 0,08771931 ! tissue homeostasis GO:0001894 42 29 1,000 0,01628528 0,08751436 GO:0048871|multicellular organismal homeostasis, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 0,0169017 0,09061519 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 2,000 0,0169017 0,09040446 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 0,01737241 0,09270657 ! positive regulation of neurogenesis GO:0050769 45 30 1,000 0,01737241 0,09249197 ! ovulation cycle GO:0042698 43 30 1,000 0,01737241 0,09227836 ! response to heat GO:0009408 41 30 1,000 0,01737241 0,09206574 ! mRNA transport GO:0051028 121 81 2,000 0,01746717 0,09235515 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,01746717 0,09214333 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,01746717 0,09193247 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 2,000 0,01804312 0,09474699 GO:0060348|bone development, ! odontogenesis GO:0042476 50 31 1,000 0,01848954 0,09687004 ! segmentation GO:0035282 41 31 1,000 0,01848954 0,09664988 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01848954 0,09643072 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,01848954 0,09621255 ! cell fate specification GO:0001708 37 31 1,000 0,01848954 0,09599536 ! leukocyte chemotaxis GO:0030595 43 31 1,000 0,01848954 0,09577916 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 1,000 0,01848954 0,09556392 ! regulation of muscle development GO:0048634 48 32 1,000 0,01963624 0,10126314 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 0,01963624 0,1010366 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,01963624 0,10081107 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,01963624 0,10058655 ! transcription initiation GO:0006352 118 85 2,000 0,019834 0,10137379 ! negative regulation of multicellular organismal process GO:0051241 133 85 2,000 0,019834 0,10114901 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02081207 0,10590211 ! ear morphogenesis GO:0042471 42 33 1,000 0,02081207 0,10566833 ! female gonad development GO:0008585 49 33 1,000 0,02081207 0,10543558 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02081207 0,10520385 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,02081207 0,10497314 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,02108053 0,10609459 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 2,000 0,02108053 0,10586294 ! establishment of RNA localization GO:0051236 128 88 2,000 0,0217196 0,1088346 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,02201657 0,11008287 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 0,02201657 0,10984407 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,02201657 0,10960632 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,02201657 0,10936959 ! female gamete generation GO:0007292 43 34 1,000 0,02201657 0,10913387 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,02201657 0,10889918 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,02201657 0,10866549 ! regulation of neurogenesis GO:0050767 153 89 2,000 0,02236921 0,11016955 ! regulation of T cell activation GO:0050863 128 89 2,000 0,02236921 0,10993414 ! glycogen metabolic process GO:0005977 48 35 1,000 0,02324933 0,1140159 ! pigment metabolic process GO:0042440 61 35 1,000 0,02324933 0,11377331 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,02324933 0,11353176 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! RNA localization GO:0006403 135 91 2,000 0,02370004 0,11548748 ! sulfur metabolic process GO:0006790 118 92 2,000 0,02438126 0,11855582 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02450991 0,11892992 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,02450991 0,11867954 ! tissue remodeling GO:0048771 62 36 1,000 0,02450991 0,11843022 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,02450991 0,11818193 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 49 36 1,000 0,02450991 0,11793469 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,02579788 0,1238729 ! learning GO:0007612 67 37 1,000 0,02579788 0,12361483 ! amino acid activation GO:0043038 52 37 1,000 0,02579788 0,12335783 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,02711282 0,12937654 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,02711282 0,12910868 ! phagocytosis GO:0006909 60 38 1,000 0,02711282 0,12884193 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 2,000 0,02721142 0,12904386 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,02845433 0,1346604 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,02845433 0,13438389 ! male sex differentiation GO:0046661 53 39 1,000 0,02845433 0,13410852 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 1,000 0,02845433 0,13383426 ! developmental growth GO:0048589 62 39 1,000 0,02845433 0,13356113 ! synapse organization GO:0050808 55 39 1,000 0,02845433 0,13328912 ! calcium ion transport GO:0006816 167 99 2,000 0,02944435 0,13764636 ! extracellular structure organization GO:0043062 156 99 2,000 0,02944435 0,13736716 ! protein import GO:0017038 156 99 2,000 0,02944435 0,13708909 ! response to calcium ion GO:0051592 58 40 1,000 0,02982198 0,13856678 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,02982198 0,13828741 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,02982198 0,13800916 ! peptide metabolic process GO:0006518 56 40 1,000 0,02982198 0,13773204 ! T cell differentiation GO:0030217 65 40 1,000 0,02982198 0,13745602 ! B cell differentiation GO:0030183 62 40 1,000 0,02982198 0,13718111 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,02982198 0,13690729 ! homophilic cell adhesion GO:0007156 149 100 2,000 0,03020961 0,13841057 ! divalent metal ion transport GO:0070838 171 100 2,000 0,03020961 0,1381354 ! protein localization in organelle GO:0033365 161 100 2,000 0,03020961 0,13786132 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03121537 0,14216902 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03121537 0,14188805 ! biopolymer methylation GO:0043414 62 41 1,000 0,03121537 0,14160819 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,0326341 0,1477528 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,0326341 0,14746252 ! embryonic skeletal system development GO:0048706 56 42 1,000 0,0326341 0,14717338 ! regulation of gene expression, epigenetic GO:0040029 72 42 1,000 0,0326341 0,14688537 ! regulation of cell shape GO:0008360 78 42 1,000 0,0326341 0,14659848 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03330022 0,14929925 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03330022 0,14900879 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03330022 0,14871945 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03330022 0,14843123 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03330022 0,14814413 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03330022 0,14785814 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03330022 0,14757325 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03330022 0,14728945 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03330022 0,14700675 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03330022 0,14672513 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03330022 0,14644458 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03330022 0,14616511 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03330022 0,1458867 ! tongue development GO:0043586 6 5 0,000 0,03330022 0,14560935 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03330022 0,14533305 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03330022 0,1450578 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03330022 0,14478358 ! cobalt ion transport GO:0006824 9 5 0,000 0,03330022 0,14451041 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03330022 0,14423826 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03330022 0,14396714 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03330022 0,14369703 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03330022 0,14342793 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03330022 0,14315984 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03330022 0,14289275 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03330022 0,14262666 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03330022 0,14236155 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03330022 0,14209743 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03330022 0,14183429 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03330022 0,14157212 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03330022 0,14131091 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03330022 0,14105067 ! malate metabolic process GO:0006108 7 5 0,000 0,03330022 0,14079139 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03330022 0,14053306 ! behavioral response to pain GO:0048266 7 5 0,000 0,03330022 0,14027567 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03330022 0,14001922 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03330022 0,13976372 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03330022 0,13950914 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03330022 0,13925548 ! mating behavior GO:0007617 6 5 0,000 0,03330022 0,13900275 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03330022 0,13875093 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03330022 0,13850003 ! copulation GO:0007620 7 5 0,000 0,03330022 0,13825003 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03330022 0,13800093 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03330022 0,13775273 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03330022 0,13750541 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03330022 0,13725899 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03330022 0,13701345 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03330022 0,13676878 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03330022 0,13652498 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03330022 0,13628206 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03330022 0,13603999 ! response to protozoan GO:0001562 9 5 0,000 0,03330022 0,13579879 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03330022 0,13555844 ! lymph vessel development GO:0001945 7 5 0,000 0,03330022 0,13531893 ! endochondral ossification GO:0001958 12 5 0,000 0,03330022 0,13508027 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03330022 0,13484246 ! parathyroid gland development GO:0060017 8 5 0,000 0,03330022 0,13460548 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03330022 0,13436933 ! anagen GO:0042640 6 5 0,000 0,03330022 0,134134 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03330022 0,1338995 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03330022 0,13366582 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03330022 0,13343295 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03330022 0,1332009 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03330022 0,13296965 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03330022 0,1327392 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03330022 0,13250954 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03330022 0,13228068 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03330022 0,13205261 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03330022 0,13182533 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03330022 0,13159882 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03330022 0,1313731 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03330022 0,13114814 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03330022 0,13092396 ! ovulation GO:0030728 6 5 0,000 0,03330022 0,13070054 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03330022 0,13047788 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 9 5 0,000 0,03330022 0,13025598 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03330022 0,13003483 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03330022 0,12981443 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03330022 0,12959478 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03330022 0,12937587 ! polyol catabolic process GO:0046174 7 5 0,000 0,03330022 0,1291577 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03330022 0,12894026 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03330022 0,12872356 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03330022 0,12850758 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03330022 0,12829232 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03330022 0,12807779 ! urea metabolic process GO:0019627 6 5 0,000 0,03330022 0,12786397 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03330022 0,12765086 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03330022 0,12743846 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03330022 0,12722677 ! neutrophil activation GO:0042119 5 5 0,000 0,03330022 0,12701578 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03330022 0,12680549 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03330022 0,12659589 ! response to food GO:0032094 5 5 0,000 0,03330022 0,12638699 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03330022 0,12617877 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03330022 0,12597124 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03330022 0,12576439 ! forebrain neuron development GO:0021884 7 5 0,000 0,03330022 0,12555822 ! melanosome organization GO:0032438 7 5 0,000 0,03330022 0,12535273 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03330022 0,1251479 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03330022 0,12494375 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03330022 0,12474025 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03330022 0,12453742 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03330022 0,12433525 ! nucleoside transport GO:0015858 6 5 0,000 0,03330022 0,12413374 ! nucleoside salvage GO:0043174 7 5 0,000 0,03330022 0,12393287 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03330022 0,12373266 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03330022 0,12353309 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03330022 0,12333416 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03330022 0,12313588 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03330022 0,12293823 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03330022 0,12274121 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03330022 0,12254483 ! depyrimidination GO:0045008 8 5 0,000 0,03330022 0,12234907 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03330022 0,12215393 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03330022 0,12195942 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03330022 0,12176553 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03330022 0,12157225 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03330022 0,12137958 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03330022 0,12118753 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03330022 0,12099608 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03330022 0,12080523 ! monocyte differentiation GO:0030224 8 5 0,000 0,03330022 0,12061499 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03330022 0,12042534 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03330022 0,12023629 ! centrosome duplication GO:0051298 5 5 0,000 0,03330022 0,12004783 ! response to UV-C GO:0010225 6 5 0,000 0,03330022 0,11985996 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03330022 0,11967268 ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03330022 0,11948598 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03330022 0,11929987 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03330022 0,11911433 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03330022 0,11892937 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03330022 0,11874499 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03330022 0,11856117 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03330022 0,11837792 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03330022 0,11819524 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03330022 0,11801312 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03330022 0,11783156 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03330022 0,11765056 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03330022 0,11747012 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03330022 0,11729022 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03330022 0,11711088 ! neural tube patterning GO:0021532 6 5 0,000 0,03330022 0,11693209 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03330022 0,11675384 ! histone demethylation GO:0016577 9 5 0,000 0,03330022 0,11657613 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03330022 0,11639896 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03330022 0,11622233 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03330022 0,11604624 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03330022 0,11587067 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03330022 0,11569564 ! transcription termination GO:0006353 8 5 0,000 0,03330022 0,11552114 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03330022 0,11534716 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03330022 0,11517371 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03330022 0,11500077 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03330022 0,11482836 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03330022 0,11465646 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03330022 0,11448508 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03330022 0,1143142 GO:0015991|ATP hydrolysis coupled proton transport, ! protein destabilization GO:0031648 6 5 0,000 0,03330022 0,11414384 ! apical protein localization GO:0045176 6 5 0,000 0,03330022 0,11397398 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03330022 0,11380463 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03330022 0,11363578 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03330022 0,11346743 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03330022 0,11329958 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03330022 0,11313222 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03330022 0,11296536 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03330022 0,11279899 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03330022 0,11263311 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03330022 0,11246772 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03330022 0,11230281 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03330022 0,11213838 ! neural plate development GO:0001840 6 5 0,000 0,03330022 0,11197444 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03330022 0,11181097 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03330022 0,11164798 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03330022 0,11148547 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03330022 0,11132342 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03330022 0,11116185 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03330022 0,11100075 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03330022 0,11084011 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03330022 0,11067994 ! spindle assembly GO:0051225 5 5 0,000 0,03330022 0,11052022 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03330022 0,11036097 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03330022 0,11020218 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03330022 0,11004384 ! organ regeneration GO:0031100 7 5 0,000 0,03330022 0,10988596 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03330022 0,10972853 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03330022 0,10957155 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03330022 0,10941502 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03330022 0,10925894 GO:0055081|anion homeostasis, ! positive regulation of binding GO:0051099 59 43 1,000 0,03407776 0,11165078 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,03407776 0,11149196 ! leukocyte migration GO:0050900 60 43 1,000 0,03407776 0,11133359 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 1,000 0,03407776 0,11117567 ! vesicle organization GO:0016050 79 43 1,000 0,03407776 0,1110182 ! methylation GO:0032259 64 43 1,000 0,03407776 0,11086117 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,03554596 0,11547418 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,03554596 0,11531131 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,03703832 0,11998329 ! cell maturation GO:0048469 60 45 1,000 0,03703832 0,11981453 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,03703832 0,11964625 ! cell redox homeostasis GO:0045454 63 46 1,000 0,03855444 0,12436915 ! histone modification GO:0016570 68 46 1,000 0,03855444 0,12419497 ! regulation of adaptive immune response GO:0002819 72 46 1,000 0,03855444 0,12402127 ! tRNA transcription GO:0009304 11 6 0,000 0,03982712 0,12793628 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03982712 0,12775785 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03982712 0,12757991 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03982712 0,12740247 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03982712 0,12722553 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03982712 0,12704907 ! regulation of helicase activity GO:0051095 11 6 0,000 0,03982712 0,1268731 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03982712 0,12669762 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,03982712 0,12652262 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03982712 0,12634811 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03982712 0,12617407 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03982712 0,12600052 ! prostate gland development GO:0030850 9 6 0,000 0,03982712 0,12582744 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03982712 0,12565484 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03982712 0,12548271 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03982712 0,12531105 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,03982712 0,12513986 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03982712 0,12496914 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03982712 0,12479888 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03982712 0,12462909 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03982712 0,12445975 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03982712 0,12429088 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03982712 0,12412246 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03982712 0,1239545 ! signal peptide processing GO:0006465 8 6 0,000 0,03982712 0,123787 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03982712 0,12361994 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03982712 0,12345334 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03982712 0,12328718 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03982712 0,12312148 ! opsonization GO:0008228 8 6 0,000 0,03982712 0,12295621 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03982712 0,12279139 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03982712 0,12262701 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03982712 0,12246307 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03982712 0,12229957 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03982712 0,1221365 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03982712 0,12197387 GO:0046530|photoreceptor cell differentiation, ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03982712 0,12181167 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03982712 0,1216499 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03982712 0,12148857 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03982712 0,12132765 ! response to interferon-gamma GO:0034341 12 6 0,000 0,03982712 0,12116717 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03982712 0,1210071 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03982712 0,12084746 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03982712 0,12068825 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03982712 0,12052945 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03982712 0,12037106 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03982712 0,12021309 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03982712 0,12005554 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03982712 0,1198984 ! thymic T cell selection GO:0045061 12 6 0,000 0,03982712 0,11974167 ! protein lipoylation GO:0009249 10 6 0,000 0,03982712 0,11958535 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03982712 0,11942944 ! drug transport GO:0015893 6 6 0,000 0,03982712 0,11927393 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03982712 0,11911883 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,03982712 0,11896413 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03982712 0,11880983 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03982712 0,11865593 ! histidine metabolic process GO:0006547 6 6 0,000 0,03982712 0,11850243 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03982712 0,11834933 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03982712 0,11819662 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03982712 0,1180443 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03982712 0,11789238 ! adenohypophysis development GO:0021984 10 6 0,000 0,03982712 0,11774085 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03982712 0,1175897 ! hyperosmotic response GO:0006972 8 6 0,000 0,03982712 0,11743895 ! microtubule nucleation GO:0007020 10 6 0,000 0,03982712 0,11728858 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03982712 0,11713859 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03982712 0,11698899 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03982712 0,11683977 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03982712 0,11669093 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03982712 0,11654247 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,03982712 0,11639438 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03982712 0,11624667 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,03982712 0,11609934 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03982712 0,11595238 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03982712 0,11580579 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03982712 0,11565957 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03982712 0,11551372 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03982712 0,11536823 ! neuron apoptosis GO:0051402 8 6 0,000 0,03982712 0,11522312 ! organic alcohol transport GO:0015850 9 6 0,000 0,03982712 0,11507836 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03982712 0,11493398 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03982712 0,11478995 ! male sex determination GO:0030238 9 6 0,000 0,03982712 0,11464628 ! carnitine transport GO:0015879 8 6 0,000 0,03982712 0,11450297 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03982712 0,11436002 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03982712 0,11421743 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03982712 0,11407519 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03982712 0,11393331 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03982712 0,11379177 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03982712 0,11365059 ! parturition GO:0007567 12 6 0,000 0,03982712 0,11350976 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03982712 0,11336928 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03982712 0,11322914 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03982712 0,11308936 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,03982712 0,11294991 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,03982712 0,11281081 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03982712 0,11267205 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03982712 0,11253363 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03982712 0,11239556 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03982712 0,11225782 ! macrophage differentiation GO:0030225 10 6 0,000 0,03982712 0,11212041 ! astrocyte development GO:0014002 14 6 0,000 0,03982712 0,11198335 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03982712 0,11184662 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03982712 0,11171022 ! interaction with symbiont GO:0051702 8 6 0,000 0,03982712 0,11157415 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03982712 0,11143842 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03982712 0,11130301 ! eating behavior GO:0042755 6 6 0,000 0,03982712 0,11116793 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03982712 0,11103319 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03982712 0,11089876 ! response to copper ion GO:0046688 9 6 0,000 0,03982712 0,11076467 ! DNA topological change GO:0006265 8 6 0,000 0,03982712 0,11063089 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03982712 0,11049744 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03982712 0,11036431 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03982712 0,1102315 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03982712 0,11009901 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03982712 0,10996684 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03982712 0,10983499 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03982712 0,10970345 ! gas homeostasis GO:0033483 11 6 0,000 0,03982712 0,10957222 ! hair follicle maturation GO:0048820 7 6 0,000 0,03982712 0,10944131 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03982712 0,10931071 ! Schwann cell development GO:0014044 14 6 0,000 0,03982712 0,10918043 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03982712 0,10905045 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03982712 0,10892078 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03982712 0,10879142 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03982712 0,10866237 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03982712 0,10853362 ! histone ubiquitination GO:0016574 7 6 0,000 0,03982712 0,10840518 ! regulation of meiosis GO:0040020 10 6 0,000 0,03982712 0,10827704 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03982712 0,10814921 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03982712 0,10802167 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03982712 0,10789444 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03982712 0,1077675 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03982712 0,10764087 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03982712 0,10751453 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03982712 0,10738849 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03982712 0,10726274 ! receptor internalization GO:0031623 9 6 0,000 0,03982712 0,10713728 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03982712 0,10701212 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03982712 0,10688726 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03982712 0,10676268 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 8 6 0,000 0,03982712 0,10663839 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03982712 0,10651439 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,03982712 0,10639068 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03982712 0,10626726 ! axonal fasciculation GO:0007413 9 6 0,000 0,03982712 0,10614412 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03982712 0,10602127 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03982712 0,1058987 ! midbrain development GO:0030901 6 6 0,000 0,03982712 0,10577642 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03982712 0,10565442 ! regulation of viral transcription GO:0046782 8 6 0,000 0,03982712 0,10553269 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03982712 0,10541125 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03982712 0,10529009 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03982712 0,10516921 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,03982712 0,1050486 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03982712 0,10492827 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03982712 0,10480821 ! adult feeding behavior GO:0008343 6 6 0,000 0,03982712 0,10468843 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03982712 0,10456892 ! blastocyst growth GO:0001832 15 6 0,000 0,03982712 0,10444969 ! pigment granule transport GO:0051904 12 6 0,000 0,03982712 0,10433073 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03982712 0,10421203 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03982712 0,10409361 ! catecholamine transport GO:0051937 7 6 0,000 0,03982712 0,10397546 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03982712 0,10385757 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03982712 0,10373995 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03982712 0,1036226 ! protein prenylation GO:0018342 10 6 0,000 0,03982712 0,10350551 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03982712 0,10338869 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03982712 0,10327213 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03982712 0,10315583 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03982712 0,1030398 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,04009394 0,10361354 ! covalent chromatin modification GO:0016569 75 47 1,000 0,04009394 0,10349725 ! response to temperature stimulus GO:0009266 62 48 1,000 0,04165644 0,1074101 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,04165644 0,10728982 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,04165644 0,1071698 ! nuclear export GO:0051168 69 48 1,000 0,04165644 0,10705006 ! germ cell development GO:0007281 68 49 1,000 0,04324157 0,11099955 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 1,000 0,04484895 0,11499731 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04631032 0,11861218 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04631032 0,11848024 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04631032 0,1183486 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04631032 0,11821725 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04631032 0,11808618 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04631032 0,11795541 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04631032 0,11782493 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04631032 0,11769474 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,04631032 0,11756483 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04631032 0,11743521 ! reproductive behavior GO:0019098 12 7 0,000 0,04631032 0,11730588 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04631032 0,11717683 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04631032 0,11704806 ! oligopeptide transport GO:0006857 11 7 0,000 0,04631032 0,11691958 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04631032 0,11679138 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04631032 0,11666346 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04631032 0,11653582 ! RNA methylation GO:0001510 11 7 0,000 0,04631032 0,11640846 ! pericardium development GO:0060039 8 7 0,000 0,04631032 0,11628137 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04631032 0,11615457 ! fibril organization GO:0043206 13 7 0,000 0,04631032 0,11602804 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04631032 0,11590178 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04631032 0,1157758 ! lipoprotein transport GO:0042953 9 7 0,000 0,04631032 0,1156501 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04631032 0,11552466 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04631032 0,1153995 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04631032 0,11527461 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04631032 0,11514999 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04631032 0,11502563 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04631032 0,11490155 ! chemosensory behavior GO:0007635 9 7 0,000 0,04631032 0,11477773 ! microtubule bundle formation GO:0001578 8 7 0,000 0,04631032 0,11465418 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04631032 0,1145309 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04631032 0,11440788 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04631032 0,11428513 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04631032 0,11416263 ! reflex GO:0060004 12 7 0,000 0,04631032 0,1140404 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04631032 0,11391844 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04631032 0,11379673 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04631032 0,11367528 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04631032 0,11355409 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,04631032 0,11343316 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04631032 0,11331249 ! spinal cord patterning GO:0021511 7 7 0,000 0,04631032 0,11319207 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,04631032 0,11307191 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,04631032 0,112952 ! adrenal gland development GO:0030325 17 7 0,000 0,04631032 0,11283235 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04631032 0,11271295 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04631032 0,1125938 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04631032 0,11247491 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04631032 0,11235626 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04631032 0,11223787 ! endosome organization GO:0007032 10 7 0,000 0,04631032 0,11211972 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04631032 0,11200183 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04631032 0,11188418 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04631032 0,11176678 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04631032 0,11164962 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04631032 0,11153271 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04631032 0,11141604 ! galactose metabolic process GO:0006012 10 7 0,000 0,04631032 0,11129962 ! vesicle fusion GO:0006906 15 7 0,000 0,04631032 0,11118344 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04631032 0,11106751 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04631032 0,11095181 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,04631032 0,11083636 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,04631032 0,11072114 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04631032 0,11060617 ! retinol metabolic process GO:0042572 9 7 0,000 0,04631032 0,11049143 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04631032 0,11037693 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04631032 0,11026267 ! rRNA modification GO:0000154 12 7 0,000 0,04631032 0,11014864 ! protein heterooligomerization GO:0051291 10 7 0,000 0,04631032 0,11003485 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04631032 0,1099213 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,04631032 0,10980798 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04631032 0,10969489 ! intermediate filament organization GO:0045109 11 7 0,000 0,04631032 0,10958203 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04631032 0,10946941 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04631032 0,10935702 ! fibrinolysis GO:0042730 9 7 0,000 0,04631032 0,10924486 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,04631032 0,10913293 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04631032 0,10902123 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04631032 0,10890975 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04631032 0,10879851 ! response to tropane GO:0014073 13 7 0,000 0,04631032 0,10868749 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04631032 0,10857669 ! melanosome localization GO:0032400 10 7 0,000 0,04631032 0,10846613 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04631032 0,10835579 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04631032 0,10824567 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04631032 0,10813577 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04631032 0,1080261 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04631032 0,10791665 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04631032 0,10780743 ! mast cell activation GO:0045576 9 7 0,000 0,04631032 0,10769842 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04631032 0,10758963 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,04631032 0,10748107 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,04631032 0,10737272 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04631032 0,10726459 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,04631032 0,10715668 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04631032 0,10704898 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04631032 0,1069415 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04631032 0,10683424 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04631032 0,10672719 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04631032 0,10662036 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04631032 0,10651374 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04631032 0,10640733 ! response to tumor cell GO:0002347 12 7 0,000 0,04631032 0,10630114 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04631032 0,10619515 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04631032 0,10608938 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04631032 0,10598382 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04631032 0,10587847 ! diuresis GO:0030146 12 7 0,000 0,04631032 0,10577332 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04631032 0,10566839 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04631032 0,10556366 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04631032 0,10545915 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04631032 0,10535483 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04631032 0,10525073 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04631032 0,10514683 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04631032 0,10504313 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04631032 0,10493964 ! lymph node development GO:0048535 9 7 0,000 0,04631032 0,10483636 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04631032 0,10473327 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04631032 0,10463039 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04631032 0,10452771 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04631032 0,10442523 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04631032 0,10432296 ! ATP catabolic process GO:0006200 10 7 0,000 0,04631032 0,10422088 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04631032 0,104119 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,04631032 0,10401732 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04631032 0,10391584 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04631032 0,10381456 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04631032 0,10371347 ! muscle adaptation GO:0043500 12 7 0,000 0,04631032 0,10361259 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04631032 0,10351189 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04631032 0,1034114 ! retina homeostasis GO:0001895 9 7 0,000 0,04631032 0,10331109 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04631032 0,10321099 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04631032 0,10311107 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04631032 0,10301135 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04631032 0,10291182 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04631032 0,10281249 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,04631032 0,10271334 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04631032 0,10261439 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,04647822 0,10288731 ! cell projection assembly GO:0030031 76 53 1,000 0,04980099 0,1101368 ! regulation of mitosis GO:0007088 84 54 1,000 0,05149377 0,11377105 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 66 54 1,000 0,05149377 0,11366187 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05275011 0,11632336 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05275011 0,11621194 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,05275011 0,11610073 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05275011 0,11598973 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05275011 0,11587895 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05275011 0,11576838 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05275011 0,11565802 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05275011 0,11554787 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05275011 0,11543793 ! phosphate transport GO:0006817 10 8 0,000 0,05275011 0,1153282 ! N-glycan processing GO:0006491 12 8 0,000 0,05275011 0,11521867 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05275011 0,11510936 ! UTP metabolic process GO:0046051 8 8 0,000 0,05275011 0,11500025 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05275011 0,11489135 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05275011 0,11478265 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05275011 0,11467416 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05275011 0,11456587 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05275011 0,11445779 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05275011 0,11434992 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05275011 0,11424224 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05275011 0,11413477 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05275011 0,1140275 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05275011 0,11392043 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05275011 0,11381357 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05275011 0,1137069 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05275011 0,11360043 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05275011 0,11349416 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05275011 0,11338809 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05275011 0,11328222 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05275011 0,11317655 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05275011 0,11307107 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,05275011 0,11296579 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05275011 0,11286071 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05275011 0,11275582 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05275011 0,11265112 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05275011 0,11254662 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05275011 0,11244232 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05275011 0,11233821 ! macrophage activation GO:0042116 12 8 0,000 0,05275011 0,11223428 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05275011 0,11213056 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05275011 0,11202702 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05275011 0,11192367 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05275011 0,11182052 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05275011 0,11171755 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05275011 0,11161478 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05275011 0,11151219 ! ruffle organization GO:0031529 11 8 0,000 0,05275011 0,11140979 ! osteoblast development GO:0002076 13 8 0,000 0,05275011 0,11130758 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05275011 0,11120556 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05275011 0,11110372 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05275011 0,11100207 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05275011 0,1109006 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05275011 0,11079933 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05275011 0,11069823 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05275011 0,11059732 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05275011 0,1104966 ! brain morphogenesis GO:0048854 20 8 0,000 0,05275011 0,11039605 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05275011 0,11029569 ! segment specification GO:0007379 10 8 0,000 0,05275011 0,11019551 ! cellular extravasation GO:0045123 11 8 0,000 0,05275011 0,11009552 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05275011 0,1099957 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05275011 0,10989607 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05275011 0,10979662 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05275011 0,10969734 GO:0016180|snRNA processing, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 0,000 0,05275011 0,10959825 ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05275011 0,10949933 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05275011 0,1094006 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05275011 0,10930204 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05275011 0,10920366 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05275011 0,10910545 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05275011 0,10900742 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05275011 0,10890957 ! icosanoid secretion GO:0032309 12 8 0,000 0,05275011 0,10881189 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05275011 0,10871439 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05275011 0,10861706 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05275011 0,10851991 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05275011 0,10842293 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05275011 0,10832613 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05275011 0,10822949 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05275011 0,10813303 ! sterol catabolic process GO:0016127 9 8 0,000 0,05275011 0,10803674 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05275011 0,10794062 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,05275011 0,10784468 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05275011 0,1077489 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05275011 0,10765329 ! prophase GO:0051324 11 8 0,000 0,05275011 0,10755786 ! S phase GO:0051320 8 8 0,000 0,05275011 0,10746259 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05275011 0,10736749 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05275011 0,10727256 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05275011 0,10717779 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05275011 0,1070832 ! hormone catabolic process GO:0042447 13 8 0,000 0,05275011 0,10698877 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05275011 0,1068945 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05275011 0,10680041 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05275011 0,10670647 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05275011 0,10661271 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05275011 0,10651911 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05275011 0,10642567 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05275011 0,10633239 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05275011 0,10623928 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05275011 0,10614634 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05275011 0,10605355 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05275011 0,10596093 ! regulation of embryonic development GO:0045995 16 8 0,000 0,05275011 0,10586847 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05275011 0,10577617 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05275011 0,10568403 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,05494035 0,10997634 ! negative regulation of response to stimulus GO:0048585 80 56 1,000 0,05494035 0,10988071 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,05669347 0,11328843 GO:0048609|reproductive process in a multicellular organism, ! secondary metabolic process GO:0019748 84 57 1,000 0,05669347 0,11319009 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,05669347 0,11309192 ! gonad development GO:0008406 79 57 1,000 0,05669347 0,11299392 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,05846601 0,11642583 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,05914679 0,1176796 ! regulation of developmental growth GO:0048638 13 9 0,000 0,05914679 0,11757788 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,05914679 0,11747635 ! telencephalon cell migration GO:0022029 16 9 0,000 0,05914679 0,11737499 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,05914679 0,1172738 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,05914679 0,11717279 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,05914679 0,11707196 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,05914679 0,11697129 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05914679 0,1168708 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,05914679 0,11677048 ! GTP metabolic process GO:0046039 9 9 0,000 0,05914679 0,11667034 ! elastic fiber assembly GO:0048251 13 9 0,000 0,05914679 0,11657036 ! social behavior GO:0035176 14 9 0,000 0,05914679 0,11647056 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,05914679 0,11637093 ! artery development GO:0060840 19 9 0,000 0,05914679 0,11627146 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,05914679 0,11617217 ! regulation of glycolysis GO:0006110 15 9 0,000 0,05914679 0,11607305 ! response to pain GO:0048265 16 9 0,000 0,05914679 0,11597409 ! protein complex disassembly GO:0043241 17 9 0,000 0,05914679 0,11587531 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,05914679 0,11577669 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,05914679 0,11567824 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,05914679 0,11557996 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,05914679 0,11548184 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,05914679 0,1153839 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,05914679 0,11528611 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,05914679 0,11518849 ! ventral spinal cord development GO:0021517 11 9 0,000 0,05914679 0,11509104 ! protein targeting to ER GO:0045047 19 9 0,000 0,05914679 0,11499376 ! endoderm development GO:0007492 12 9 0,000 0,05914679 0,11489663 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,05914679 0,11479967 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,05914679 0,11470288 ! arginine catabolic process GO:0006527 10 9 0,000 0,05914679 0,11460624 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,05914679 0,11450977 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,05914679 0,11441347 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,05914679 0,11431732 ! V(D)J recombination GO:0033151 12 9 0,000 0,05914679 0,11422134 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,05914679 0,11412551 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,05914679 0,11402985 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,05914679 0,11393435 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05914679 0,11383901 ! mannose metabolic process GO:0006013 9 9 0,000 0,05914679 0,11374382 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,05914679 0,1136488 ! receptor clustering GO:0043113 15 9 0,000 0,05914679 0,11355393 ! epithelial cell development GO:0002064 10 9 0,000 0,05914679 0,11345923 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,05914679 0,11336468 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,05914679 0,11327029 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,05914679 0,11317605 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,05914679 0,11308197 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,05914679 0,11298805 ! motor axon guidance GO:0008045 14 9 0,000 0,05914679 0,11289428 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,05914679 0,11280067 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,05914679 0,11270722 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,05914679 0,11261392 ! blastoderm segmentation GO:0007350 11 9 0,000 0,05914679 0,11252077 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,05914679 0,11242778 ! DNA ligation GO:0006266 14 9 0,000 0,05914679 0,11233494 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,05914679 0,11224225 ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,05914679 0,11214972 ! erythrocyte development GO:0048821 11 9 0,000 0,05914679 0,11205734 ! renal water homeostasis GO:0003091 14 9 0,000 0,05914679 0,11196511 ! postreplication repair GO:0006301 11 9 0,000 0,05914679 0,11187304 ! mRNA cleavage GO:0006379 13 9 0,000 0,05914679 0,11178111 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,05914679 0,11168934 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,05914679 0,11159771 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,05914679 0,11150624 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,05914679 0,11141492 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,05914679 0,11132374 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,05914679 0,11123272 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,05914679 0,11114184 ! acid secretion GO:0046717 14 9 0,000 0,05914679 0,11105111 ! musculoskeletal movement GO:0050881 11 9 0,000 0,05914679 0,11096053 GO:0050879|multicellular organismal movement, ! methionine biosynthetic process GO:0009086 10 9 0,000 0,05914679 0,1108701 ! purine base metabolic process GO:0006144 18 9 0,000 0,05914679 0,11077981 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,05914679 0,11068968 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,05914679 0,11059968 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,05914679 0,11050984 ! detection of calcium ion GO:0005513 13 9 0,000 0,05914679 0,11042014 ! blastocyst formation GO:0001825 12 9 0,000 0,05914679 0,11033059 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,05914679 0,11024118 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,05914679 0,11015191 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,05914679 0,11006279 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,05914679 0,10997382 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05914679 0,10988499 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,05914679 0,1097963 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,05914679 0,10970775 ! prepulse inhibition GO:0060134 14 9 0,000 0,05914679 0,10961935 ! embryonic placenta development GO:0001892 12 9 0,000 0,05914679 0,10953109 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,05914679 0,10944297 ! insulin secretion GO:0030073 17 9 0,000 0,05914679 0,10935499 ! sequestering of metal ion GO:0051238 11 9 0,000 0,05914679 0,10926716 ! establishment of cell polarity GO:0030010 12 9 0,000 0,05914679 0,10917946 ! nucleus localization GO:0051647 15 9 0,000 0,05914679 0,10909191 ! regulation of synapse organization GO:0050807 12 9 0,000 0,05914679 0,1090045 ! localization within membrane GO:0051668 15 9 0,000 0,05914679 0,10891722 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,06025764 0,11087407 ! activation of MAPK activity GO:0000187 84 59 1,000 0,06025764 0,11078544 ! actin filament organization GO:0007015 95 59 1,000 0,06025764 0,11069695 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,06025764 0,11060861 ! regulation of heart contraction GO:0008016 91 60 1,000 0,06206803 0,11384089 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,06389685 0,11710179 ! extracellular matrix organization GO:0030198 103 61 1,000 0,06389685 0,11700856 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,06389685 0,11691547 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of muscle development GO:0048635 12 10 0,000 0,06550063 0,11975473 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,06550063 0,11965961 ! neuron fate specification GO:0048665 11 10 0,000 0,06550063 0,11956464 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,06550063 0,11946982 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,06550063 0,11937516 ! thyroid gland development GO:0030878 19 10 0,000 0,06550063 0,11928064 ! synapsis GO:0007129 13 10 0,000 0,06550063 0,11918627 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,06550063 0,11909205 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,06550063 0,11899798 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,06550063 0,11890406 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,06550063 0,11881029 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,06550063 0,11871667 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,06550063 0,11862319 ! androgen metabolic process GO:0008209 13 10 0,000 0,06550063 0,11852986 ! phospholipid efflux GO:0033700 16 10 0,000 0,06550063 0,11843667 ! hippocampus development GO:0021766 19 10 0,000 0,06550063 0,11834364 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,06550063 0,11825074 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,06550063 0,118158 ! pathogenesis GO:0009405 13 10 0,000 0,06550063 0,1180654 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,06550063 0,11797294 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06550063 0,11788063 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,06550063 0,11778847 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,06550063 0,11769644 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,06550063 0,11760457 ! melanocyte differentiation GO:0030318 15 10 0,000 0,06550063 0,11751283 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,06550063 0,11742124 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,06550063 0,11732979 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06550063 0,11723848 ! response to X-ray GO:0010165 16 10 0,000 0,06550063 0,11714732 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,06550063 0,11705629 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,06550063 0,11696541 ! forebrain cell migration GO:0021885 17 10 0,000 0,06550063 0,11687467 ! lipid digestion GO:0044241 15 10 0,000 0,06550063 0,11678407 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,06550063 0,11669361 ! UV protection GO:0009650 14 10 0,000 0,06550063 0,11660329 ! entry into host cell GO:0030260 20 10 0,000 0,06550063 0,11651311 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,06550063 0,11642307 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,06550063 0,11633317 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,06550063 0,1162434 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,06550063 0,11615378 ! response to dsRNA GO:0043331 18 10 0,000 0,06550063 0,11606429 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,06550063 0,11597494 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06550063 0,11588573 ! embryonic axis specification GO:0000578 12 10 0,000 0,06550063 0,11579666 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,06550063 0,11570772 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,06550063 0,11561892 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,06550063 0,11553025 ! fucose catabolic process GO:0019317 16 10 0,000 0,06550063 0,11544172 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,06550063 0,11535333 ! protein sumoylation GO:0016925 12 10 0,000 0,06550063 0,11526507 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,06550063 0,11517695 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06550063 0,11508896 ! zymogen activation GO:0031638 14 10 0,000 0,06550063 0,11500111 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06550063 0,11491339 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,06550063 0,1148258 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,06550063 0,11473835 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,06550063 0,11465103 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,06550063 0,11456384 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06550063 0,11447678 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,06550063 0,11438986 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,06550063 0,11430307 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,06550063 0,11421641 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,06550063 0,11412989 ! detection of bacterium GO:0016045 10 10 0,000 0,06550063 0,11404349 ! activation of innate immune response GO:0002218 10 10 0,000 0,06550063 0,11395722 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,06550063 0,11387109 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,06550063 0,11378508 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,06550063 0,11369921 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,06550063 0,11361346 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,06550063 0,11352784 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,06760845 0,11709295 ! adaptive immune response GO:0002250 94 64 1,000 0,0694906 0,12026214 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 1,000 0,07138989 0,12345621 ! B cell activation GO:0042113 104 65 1,000 0,07138989 0,12336345 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,07138989 0,12327084 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,07138989 0,12317836 ! rRNA transcription GO:0009303 17 11 0,000 0,07181192 0,12381366 ! respiratory burst GO:0045730 14 11 0,000 0,07181192 0,12372092 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07181192 0,12362831 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07181192 0,12353584 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07181192 0,12344352 ! virus-host interaction GO:0019048 17 11 0,000 0,07181192 0,12335133 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,07181192 0,12325927 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07181192 0,12316736 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07181192 0,12307558 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07181192 0,12298393 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07181192 0,12289243 ! mating GO:0007618 14 11 0,000 0,07181192 0,12280106 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,07181192 0,12270983 ! T cell proliferation GO:0042098 20 11 0,000 0,07181192 0,12261873 ! bone resorption GO:0045453 16 11 0,000 0,07181192 0,12252776 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07181192 0,12243693 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07181192 0,12234624 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07181192 0,12225568 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07181192 0,12216525 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07181192 0,12207496 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07181192 0,1219848 ! syncytium formation GO:0006949 15 11 0,000 0,07181192 0,12189478 ! plasma membrane organization GO:0007009 18 11 0,000 0,07181192 0,12180489 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07181192 0,12171512 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07181192 0,1216255 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07181192 0,121536 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,07181192 0,12144664 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07181192 0,1213574 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07181192 0,1212683 ! adult heart development GO:0007512 11 11 0,000 0,07181192 0,12117933 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,07181192 0,12109049 ! temperature homeostasis GO:0001659 16 11 0,000 0,07181192 0,12100178 ! L-glutamate transport GO:0015813 16 11 0,000 0,07181192 0,1209132 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07181192 0,12082474 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07181192 0,12073642 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07181192 0,12064823 ! stem cell development GO:0048864 29 11 0,000 0,07181192 0,12056016 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07181192 0,12047223 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07181192 0,12038442 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07181192 0,12029674 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07181192 0,12020919 ! vasoconstriction GO:0042310 15 11 0,000 0,07181192 0,12012176 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07181192 0,12003447 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07181192 0,11994729 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07181192 0,11986025 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07181192 0,11977333 ! ribosome assembly GO:0042255 13 11 0,000 0,07181192 0,11968654 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07181192 0,11959987 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07181192 0,11951333 ! chromatin silencing GO:0006342 19 11 0,000 0,07181192 0,11942692 ! nucleosome positioning GO:0016584 13 11 0,000 0,07181192 0,11934062 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07181192 0,11925446 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07181192 0,11916842 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07181192 0,1190825 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07181192 0,1189967 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07181192 0,11891103 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07181192 0,11882549 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07181192 0,11874006 ! male genitalia development GO:0030539 13 11 0,000 0,07181192 0,11865476 ! cholesterol efflux GO:0033344 19 11 0,000 0,07181192 0,11856958 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07181192 0,11848452 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07181192 0,11839959 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,07181192 0,11831477 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,07181192 0,11823008 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07181192 0,11814551 ! defense response to fungus GO:0050832 12 11 0,000 0,07181192 0,11806106 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07181192 0,11797673 ! lysogeny GO:0030069 18 11 0,000 0,07181192 0,11789252 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07181192 0,11780843 ! acrosome reaction GO:0007340 13 11 0,000 0,07181192 0,11772447 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07181192 0,11764062 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,07523865 0,12316648 ! learning or memory GO:0007611 123 68 1,000 0,07718751 0,12626691 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,07718751 0,12617716 ! lactation GO:0007595 20 12 0,000 0,07808095 0,12754701 ! reproductive cellular process GO:0048610 14 12 0,000 0,07808095 0,12745649 ! tRNA modification GO:0006400 14 12 0,000 0,07808095 0,12736609 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,07808095 0,12727583 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,07808095 0,12718569 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,07808095 0,12709568 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,07808095 0,12700579 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,07808095 0,12691604 ! non-recombinational repair GO:0000726 19 12 0,000 0,07808095 0,12682641 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,07808095 0,1267369 ! peroxisomal transport GO:0043574 21 12 0,000 0,07808095 0,12664752 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,07808095 0,12655827 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,07808095 0,12646915 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,07808095 0,12638015 ! heart looping GO:0001947 15 12 0,000 0,07808095 0,12629127 ! palate development GO:0060021 15 12 0,000 0,07808095 0,12620252 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,07808095 0,1261139 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,07808095 0,1260254 ! arginine metabolic process GO:0006525 13 12 0,000 0,07808095 0,12593702 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,07808095 0,12584877 ! methionine metabolic process GO:0006555 13 12 0,000 0,07808095 0,12576064 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,07808095 0,12567263 ! Golgi organization GO:0007030 18 12 0,000 0,07808095 0,12558475 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,07808095 0,12549699 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,07808095 0,12540935 ! monoamine transport GO:0015844 13 12 0,000 0,07808095 0,12532184 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07808095 0,12523444 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,07808095 0,12514717 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,07808095 0,12506002 ! L-amino acid transport GO:0015807 20 12 0,000 0,07808095 0,12497299 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,07808095 0,12488608 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,07808095 0,1247993 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,07808095 0,12471263 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07808095 0,12462609 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,07808095 0,12453966 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,07808095 0,12445335 ! cerebellum development GO:0021549 13 12 0,000 0,07808095 0,12436717 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,07808095 0,1242811 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,07808095 0,12419515 ! histone methylation GO:0016571 15 12 0,000 0,07808095 0,12410932 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,07808095 0,12402361 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,07808095 0,12393802 ! intestinal absorption GO:0050892 19 12 0,000 0,07808095 0,12385254 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,07808095 0,12376719 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,07808095 0,12368195 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,07808095 0,12359683 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,07808095 0,12351182 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,07808095 0,12342693 ! microspike assembly GO:0030035 23 12 0,000 0,07808095 0,12334216 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,07808095 0,12325751 ! response to cold GO:0009409 14 12 0,000 0,07808095 0,12317297 ! humoral immune response GO:0006959 86 70 1,000 0,08113265 0,12789932 ! eye development GO:0001654 111 70 1,000 0,08113265 0,12781171 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,08113265 0,12772423 ! muscle cell differentiation GO:0042692 104 71 1,000 0,08312835 0,13077647 ! lymphocyte differentiation GO:0030098 113 71 1,000 0,08312835 0,13068708 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,084308 0,13245109 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,084308 0,13236068 ! cGMP metabolic process GO:0046068 16 13 0,000 0,084308 0,13227039 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,084308 0,13218022 ! water transport GO:0006833 17 13 0,000 0,084308 0,13209018 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,084308 0,13200027 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,084308 0,13191047 ! lipid localization GO:0010876 24 13 0,000 0,084308 0,13182079 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,084308 0,13173124 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,084308 0,13164181 ! organelle fusion GO:0048284 28 13 0,000 0,084308 0,1315525 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,084308 0,13146331 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,084308 0,13137425 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,084308 0,1312853 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,084308 0,13119647 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,084308 0,13110777 ! response to hexose stimulus GO:0009746 19 13 0,000 0,084308 0,13101918 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,084308 0,13093072 ! glutamate metabolic process GO:0006536 18 13 0,000 0,084308 0,13084237 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,084308 0,13075414 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,084308 0,13066603 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,084308 0,13057804 ! NAD metabolic process GO:0019674 21 13 0,000 0,084308 0,13049017 ! bone mineralization GO:0030282 15 13 0,000 0,084308 0,13040241 ! regulation of exocytosis GO:0017157 17 13 0,000 0,084308 0,13031478 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,084308 0,13022726 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,084308 0,13013986 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,084308 0,13005258 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,084308 0,12996541 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,084308 0,12987836 ! genitalia development GO:0048806 15 13 0,000 0,084308 0,12979143 ! regulation of cellular pH GO:0030641 20 13 0,000 0,084308 0,12970461 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,084308 0,12961791 ! tissue regeneration GO:0042246 21 13 0,000 0,084308 0,12953132 ! cofactor transport GO:0051181 19 13 0,000 0,084308 0,12944485 ! NADP metabolic process GO:0006739 18 13 0,000 0,084308 0,1293585 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,084308 0,12927226 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,084308 0,12918614 ! gas transport GO:0015669 18 13 0,000 0,084308 0,12910013 ! heme biosynthetic process GO:0006783 20 13 0,000 0,084308 0,12901423 ! regulation of axon extension GO:0030516 23 13 0,000 0,084308 0,12892845 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,084308 0,12884278 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,084308 0,12875723 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,084308 0,12867179 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,084308 0,12858647 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,08513907 0,12976796 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,08716452 0,13276715 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,08920442 0,13578436 ! superoxide anion generation GO:0042554 18 14 0,000 0,09049333 0,1376552 ! neuron maturation GO:0042551 21 14 0,000 0,09049333 0,13756422 ! regulation of S phase GO:0033261 18 14 0,000 0,09049333 0,13747336 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09049333 0,13738262 ! myotube differentiation GO:0014902 21 14 0,000 0,09049333 0,137292 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,09049333 0,13720149 ! inositol metabolic process GO:0006020 20 14 0,000 0,09049333 0,13711111 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09049333 0,13702085 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09049333 0,1369307 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09049333 0,13684067 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09049333 0,13675077 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09049333 0,13666098 ! response to cAMP GO:0051591 19 14 0,000 0,09049333 0,1365713 ! limbic system development GO:0021761 25 14 0,000 0,09049333 0,13648175 ! startle response GO:0001964 21 14 0,000 0,09049333 0,13639231 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09049333 0,13630299 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09049333 0,13621379 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09049333 0,1361247 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09049333 0,13603573 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09049333 0,13594687 ! glycine metabolic process GO:0006544 22 14 0,000 0,09049333 0,13585814 ! pituitary gland development GO:0021983 23 14 0,000 0,09049333 0,13576951 ! cellular response to starvation GO:0009267 21 14 0,000 0,09049333 0,13568101 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,09049333 0,13559262 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,09049333 0,13550434 ! regulation of heart rate GO:0002027 23 14 0,000 0,09049333 0,13541618 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09049333 0,13532813 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09049333 0,1352402 ! embryo implantation GO:0007566 27 14 0,000 0,09049333 0,13515238 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,09049333 0,13506468 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,09049333 0,13497708 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09049333 0,13488961 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09049333 0,13480224 ! axon cargo transport GO:0008088 27 14 0,000 0,09049333 0,13471499 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09049333 0,13462786 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09049333 0,13454083 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09049333 0,13445392 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09049333 0,13436712 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09049333 0,13428043 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09049333 0,13419385 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09049333 0,13410739 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09049333 0,13402103 ! muscle maintenance GO:0046716 19 14 0,000 0,09049333 0,13393479 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09049333 0,13384866 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09049333 0,13376264 ! cell killing GO:0001906 20 14 0,000 0,09049333 0,13367673 ! cilium assembly GO:0042384 20 14 0,000 0,09049333 0,13359093 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09049333 0,13350524 ! amine biosynthetic process GO:0009309 97 76 1,000 0,09332644 0,13759667 ! tRNA metabolic process GO:0006399 95 76 1,000 0,09332644 0,13750852 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,09540799 0,14048552 ! sex differentiation GO:0007548 105 77 1,000 0,09540799 0,14039564 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,09540799 0,14030587 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,09663724 0,14202278 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,09663724 0,14193209 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,09663724 0,14184151 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,09663724 0,14175105 ! skin development GO:0043588 25 15 0,000 0,09663724 0,14166071 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,09663724 0,14157048 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,09663724 0,14148037 ! lipid phosphorylation GO:0046834 23 15 0,000 0,09663724 0,14139036 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,09663724 0,14130048 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,09663724 0,14121071 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,09663724 0,14112105 ! bile acid metabolic process GO:0008206 22 15 0,000 0,09663724 0,14103151 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,09663724 0,14094208 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,09663724 0,14085276 ! adult walking behavior GO:0007628 25 15 0,000 0,09663724 0,14076356 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,09663724 0,14067446 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,09663724 0,14058549 ! myoblast differentiation GO:0045445 27 15 0,000 0,09663724 0,14049662 ! centrosome cycle GO:0007098 16 15 0,000 0,09663724 0,14040787 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,09663724 0,14031923 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,09663724 0,1402307 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,09663724 0,14014228 ! cerebral cortex development GO:0021987 29 15 0,000 0,09663724 0,14005397 ! response to osmotic stress GO:0006970 22 15 0,000 0,09663724 0,13996578 ! vesicle coating GO:0006901 25 15 0,000 0,09663724 0,13987769 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,09663724 0,13978972 ! DNA integration GO:0015074 22 15 0,000 0,09663724 0,13970186 ! peptide secretion GO:0002790 27 15 0,000 0,09663724 0,1396141 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,09663724 0,13952646 ! regulation of vasodilation GO:0042312 24 15 0,000 0,09663724 0,13943893 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,09663724 0,13935151 ! neuron recognition GO:0008038 22 15 0,000 0,09663724 0,13926419 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,09663724 0,13917699 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,09663724 0,1390899 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,09663724 0,13900291 ! biomineral formation GO:0031214 18 15 0,000 0,09663724 0,13891603 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,09663724 0,13882927 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,09663724 0,13874261 ! organic cation transport GO:0015695 19 15 0,000 0,09663724 0,13865605 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,09663724 0,13856961 GO:0033014|tetrapyrrole biosynthetic process, ! peptide hormone processing GO:0016486 19 15 0,000 0,09663724 0,13848327 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,09663724 0,13839704 ! T cell activation GO:0042110 134 79 1,000 0,09961084 0,14256685 ! protein secretion GO:0009306 27 16 0,000 0,10273999 0,14695397 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,10273999 0,14686264 ! hormone secretion GO:0046879 25 16 0,000 0,10273999 0,14677142 ! bone remodeling GO:0046849 24 16 0,000 0,10273999 0,14668032 ! endothelial cell migration GO:0043542 22 16 0,000 0,10273999 0,14658932 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,10273999 0,14649844 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10273999 0,14640768 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,10273999 0,14631702 ! glial cell development GO:0021782 24 16 0,000 0,10273999 0,14622648 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,10273999 0,14613605 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,10273999 0,14604573 ! protein polyubiquitination GO:0000209 26 16 0,000 0,10273999 0,14595552 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,10273999 0,14586542 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,10273999 0,14577544 ! fructose metabolic process GO:0006000 20 16 0,000 0,10273999 0,14568557 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,10273999 0,1455958 ! protein export from nucleus GO:0006611 24 16 0,000 0,10273999 0,14550615 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,10273999 0,14541661 ! DNA replication initiation GO:0006270 25 16 0,000 0,10273999 0,14532718 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,10273999 0,14523785 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,10273999 0,14514864 ! diencephalon development GO:0021536 25 16 0,000 0,10273999 0,14505954 ! neural crest cell migration GO:0001755 24 16 0,000 0,10273999 0,14497054 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,10273999 0,14488166 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,10273999 0,14479288 ! steroid catabolic process GO:0006706 22 16 0,000 0,10273999 0,14470422 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,10273999 0,14461566 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,10273999 0,14452721 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,10273999 0,14443887 ! sperm-egg recognition GO:0035036 16 16 0,000 0,10273999 0,14435063 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,10273999 0,14426251 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,10273999 0,14417449 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,10273999 0,14408658 ! negative regulation of translation GO:0017148 22 16 0,000 0,10273999 0,14399877 ! regulation of neurological system process GO:0031644 122 81 1,000 0,10386486 0,14548671 ! detection of stimulus GO:0051606 108 82 1,000 0,1060104 0,14840166 ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,10816795 0,15132986 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,10880187 0,15212419 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,10880187 0,15203177 ! negative regulation of defense response GO:0031348 19 17 0,000 0,10880187 0,15193946 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,10880187 0,15184727 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,10880187 0,15175518 ! glycerol metabolic process GO:0006071 20 17 0,000 0,10880187 0,15166321 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,10880187 0,15157135 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,10880187 0,1514796 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,10880187 0,15138796 ! signal complex assembly GO:0007172 29 17 0,000 0,10880187 0,15129643 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,10880187 0,15120501 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,10880187 0,15111371 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,10880187 0,15102251 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,10880187 0,15093142 ! memory GO:0007613 25 17 0,000 0,10880187 0,15084044 ! keratinization GO:0031424 17 17 0,000 0,10880187 0,15074958 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,10880187 0,15065882 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,10880187 0,15056817 ! retinoid metabolic process GO:0001523 22 17 0,000 0,10880187 0,15047763 GO:0016101|diterpenoid metabolic process, ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,10880187 0,1503872 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,10880187 0,15029687 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,10880187 0,15020666 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,10880187 0,15011655 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,10880187 0,15002656 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,10880187 0,14993667 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,10880187 0,14984688 ! membrane budding GO:0006900 29 17 0,000 0,10880187 0,14975721 ! heme metabolic process GO:0042168 27 17 0,000 0,10880187 0,14966764 ! actin filament bundle formation GO:0051017 26 17 0,000 0,10880187 0,14957818 ! neuromuscular junction development GO:0007528 23 17 0,000 0,10880187 0,14948883 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,10880187 0,14939958 ! body fluid secretion GO:0007589 27 17 0,000 0,10880187 0,14931044 ! stem cell differentiation GO:0048863 36 17 0,000 0,10880187 0,14922141 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,10880187 0,14913248 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,10880187 0,14904366 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,10880187 0,14895494 ! sensory perception of pain GO:0019233 23 17 0,000 0,10880187 0,14886633 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,10880187 0,14877782 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,10880187 0,14868942 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,10880187 0,14860113 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,10880187 0,14851294 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,10880187 0,14842485 ! cell-cell junction organization GO:0045216 25 17 0,000 0,10880187 0,14833687 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,10880187 0,14824899 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,10880187 0,14816122 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,10880187 0,14807355 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,10880187 0,14798598 ! sterol metabolic process GO:0016125 120 84 1,000 0,11033726 0,14998563 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,11251806 0,15285974 ! rRNA metabolic process GO:0016072 107 85 1,000 0,11251806 0,1527695 GO:0006364|rRNA processing, ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,11251806 0,15267937 ! regulation of membrane potential GO:0042391 128 85 1,000 0,11251806 0,15258935 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,11482313 0,15562357 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,11482313 0,15553192 ! positive regulation of translation GO:0045727 28 18 0,000 0,11482313 0,15544038 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,11482313 0,15534894 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,11482313 0,15525762 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,11482313 0,1551664 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,11482313 0,15507528 ! cAMP metabolic process GO:0046058 33 18 0,000 0,11482313 0,15498427 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,11482313 0,15489338 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,11482313 0,15480258 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,11482313 0,15471189 ! axis specification GO:0009798 26 18 0,000 0,11482313 0,15462131 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,11482313 0,15453084 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,11482313 0,15444047 ! pancreas development GO:0031016 26 18 0,000 0,11482313 0,15435021 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,11482313 0,15426005 ! glutamine metabolic process GO:0006541 23 18 0,000 0,11482313 0,15417 ! response to retinoic acid GO:0032526 25 18 0,000 0,11482313 0,15408005 ! pigmentation during development GO:0048066 31 18 0,000 0,11482313 0,15399021 ! central nervous system neuron development GO:0021954 30 18 0,000 0,11482313 0,15390047 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,11482313 0,15381084 ! fucose metabolic process GO:0006004 26 18 0,000 0,11482313 0,15372131 ! response to fungus GO:0009620 19 18 0,000 0,11482313 0,15363188 ! peptide cross-linking GO:0018149 31 18 0,000 0,11482313 0,15354256 ! heart process GO:0003015 27 18 0,000 0,11482313 0,15345334 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,11482313 0,15336423 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 35 18 0,000 0,11482313 0,15327522 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,11482313 0,15318631 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,11482313 0,15309751 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,11482313 0,15300881 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,11482313 0,15292021 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,11482313 0,15283172 ! vitamin transport GO:0051180 24 18 0,000 0,11482313 0,15274332 ! hormone transport GO:0009914 27 18 0,000 0,11482313 0,15265503 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,11482313 0,15256684 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,11482313 0,15247876 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,11482313 0,15239077 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,11482313 0,15230289 ! cell-cell recognition GO:0009988 20 18 0,000 0,11482313 0,1522151 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,11482313 0,15212742 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,11482313 0,15203984 ! regulation of glucose import GO:0046324 21 18 0,000 0,11482313 0,15195236 GO:0010827|regulation of glucose transport, ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,11482313 0,15186498 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,11482313 0,1517777 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,11691316 0,15445161 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,11912696 0,15728588 ! protein processing GO:0016485 114 88 1,000 0,11912696 0,15719565 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,12080406 0,15931728 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,12080406 0,15922598 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,12080406 0,15913478 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,12080406 0,15904369 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,12080406 0,15895271 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,12080406 0,15886182 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,12080406 0,15877105 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,12080406 0,15868037 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,12080406 0,1585898 ! sensory perception of taste GO:0050909 23 19 0,000 0,12080406 0,15849933 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,12080406 0,15840897 ! smooth muscle contraction GO:0006939 36 19 0,000 0,12080406 0,15831871 ! peroxisome organization GO:0007031 29 19 0,000 0,12080406 0,15822855 ! digestive system process GO:0022600 30 19 0,000 0,12080406 0,15813849 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,12080406 0,15804854 ! response to vitamin A GO:0033189 26 19 0,000 0,12080406 0,15795869 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,12080406 0,15786894 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,12080406 0,15777929 ! response to starvation GO:0042594 30 19 0,000 0,12080406 0,15768975 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,12080406 0,1576003 ! plasma membrane fusion GO:0045026 23 19 0,000 0,12080406 0,15751096 ! cytolysis GO:0019835 20 19 0,000 0,12080406 0,15742172 ! vasodilation GO:0042311 33 19 0,000 0,12080406 0,15733258 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,12080406 0,15724354 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,12080406 0,1571546 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,12080406 0,15706576 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,12080406 0,15697702 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,12080406 0,15688839 ! sarcomere organization GO:0045214 23 19 0,000 0,12080406 0,15679985 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,12080406 0,15671141 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,12080406 0,15662307 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,12080406 0,15653483 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,12080406 0,1564467 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,12080406 0,15635866 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,12080406 0,15627072 ! protein stabilization GO:0050821 26 19 0,000 0,12080406 0,15618287 ! leukocyte differentiation GO:0002521 143 90 1,000 0,12358587 0,1596896 ! response to virus GO:0009615 122 91 1,000 0,12583049 0,16249867 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,12674491 0,16358771 ! iron ion transport GO:0006826 37 20 0,000 0,12674491 0,16349596 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,12674491 0,16340431 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,12674491 0,16331277 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,12674491 0,16322133 ! response to vitamin GO:0033273 29 20 0,000 0,12674491 0,16312999 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,12674491 0,16303876 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,12674491 0,16294762 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,12674491 0,16285659 ! spinal cord development GO:0021510 31 20 0,000 0,12674491 0,16276566 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,12674491 0,16267483 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,12674491 0,1625841 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,12674491 0,16249348 ! chromosome condensation GO:0030261 31 20 0,000 0,12674491 0,16240295 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,12674491 0,16231252 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,12674491 0,1622222 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,12674491 0,16213198 ! pallium development GO:0021543 38 20 0,000 0,12674491 0,16204185 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,12674491 0,16195183 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,12674491 0,16186191 ! collagen catabolic process GO:0030574 25 20 0,000 0,12674491 0,16177208 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,12674491 0,16168236 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,12674491 0,16159274 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,12674491 0,16150321 ! alditol metabolic process GO:0019400 24 20 0,000 0,12674491 0,16141378 ! actin filament-based movement GO:0030048 34 20 0,000 0,12674491 0,16132446 ! positive regulation of immune response GO:0050778 121 92 1,000 0,12808492 0,16293989 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,13034892 0,16572831 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,13264596 0,16855564 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,13264596 0,16846256 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,13264596 0,16836959 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,13264596 0,16827673 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,13264596 0,16818396 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,13264596 0,1680913 ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,13264596 0,16799874 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,13264596 0,16790628 ! vesicle docking GO:0048278 27 21 0,000 0,13264596 0,16781392 ! phototransduction GO:0007602 25 21 0,000 0,13264596 0,16772166 ! dendrite development GO:0016358 35 21 0,000 0,13264596 0,16762951 ! visual behavior GO:0007632 39 21 0,000 0,13264596 0,16753745 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,13264596 0,1674455 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,13264596 0,16735365 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,13264596 0,1672619 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,13264596 0,16717025 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,13264596 0,1670787 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,13264596 0,16698725 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,13264596 0,1668959 GO:0060415|muscle tissue morphogenesis, ! leukotriene metabolic process GO:0006691 28 21 0,000 0,13264596 0,16680465 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,13264596 0,1667135 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,13264596 0,16662245 ! fatty acid transport GO:0015908 30 21 0,000 0,13264596 0,1665315 ! immunoglobulin production GO:0002377 33 21 0,000 0,13264596 0,16644065 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,13264596 0,16634989 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,13264596 0,16625924 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,13264596 0,16616868 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,13264596 0,16607823 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,13264596 0,16598787 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,13264596 0,16589761 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,13264596 0,16580745 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,13264596 0,16571738 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,13264596 0,16562742 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,13264596 0,16553755 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,13264596 0,16544778 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,13719606 0,17103032 ! protein maturation GO:0051604 129 96 1,000 0,13719606 0,17093767 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,13850747 0,17247817 ! viral genome replication GO:0019079 29 22 0,000 0,13850747 0,17238483 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,13850747 0,1722916 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,13850747 0,17219847 ! leukocyte adhesion GO:0007159 38 22 0,000 0,13850747 0,17210544 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,13850747 0,17201251 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,13850747 0,17191968 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,13850747 0,17182695 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,13850747 0,17173432 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,13850747 0,17164179 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,13850747 0,17154937 ! lysosome organization GO:0007040 37 22 0,000 0,13850747 0,17145704 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,13850747 0,1713648 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,13850747 0,17127267 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,13850747 0,17118064 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,13850747 0,17108871 ! membrane depolarization GO:0051899 35 22 0,000 0,13850747 0,17099687 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,13850747 0,17090513 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,13850747 0,1708135 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,13850747 0,17072196 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,13850747 0,17063051 ! blastocyst development GO:0001824 37 22 0,000 0,13850747 0,17053917 ! neural tube closure GO:0001843 33 22 0,000 0,13850747 0,17044792 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,13850747 0,17035678 ! protein tetramerization GO:0051262 39 22 0,000 0,13850747 0,17026572 ! neuron fate commitment GO:0048663 32 23 0,000 0,14432969 0,17732815 ! embryonic pattern specification GO:0009880 31 23 0,000 0,14432969 0,17723347 ! myelination GO:0042552 35 23 0,000 0,14432969 0,1771389 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,14432969 0,17704443 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,14432969 0,17695005 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,14432969 0,17685578 ! vesicle targeting GO:0006903 32 23 0,000 0,14432969 0,17676161 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,14432969 0,17666753 ! interaction with host GO:0051701 37 23 0,000 0,14432969 0,17657356 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,14432969 0,17647969 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,14432969 0,17638592 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,14432969 0,17629225 ! cell fate determination GO:0001709 45 23 0,000 0,14432969 0,17619867 ! pentose metabolic process GO:0019321 31 23 0,000 0,14432969 0,1761052 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,14432969 0,17601182 ! spermatid development GO:0007286 33 23 0,000 0,14432969 0,17591855 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,14432969 0,17582537 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,14432969 0,17573229 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,14432969 0,17563931 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,14432969 0,17554643 ! telomere organization GO:0032200 32 23 0,000 0,14432969 0,17545365 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,14432969 0,17536096 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,14432969 0,17526837 ! regulation of amine transport GO:0051952 38 23 0,000 0,14432969 0,17517588 ! regulation of translation GO:0006417 151 100 1,000 0,14644598 0,17765071 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,15011291 0,182003 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,15011291 0,1819071 ! initiation of viral infection GO:0019059 42 24 0,000 0,15011291 0,18181131 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,15011291 0,18171562 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,15011291 0,18162003 ! superoxide metabolic process GO:0006801 32 24 0,000 0,15011291 0,18152455 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,15011291 0,18142916 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! insulin receptor signaling pathway GO:0008286 40 24 0,000 0,15011291 0,18133387 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,15011291 0,18123868 ! sperm motility GO:0030317 27 24 0,000 0,15011291 0,18114359 ! vacuole organization GO:0007033 39 24 0,000 0,15011291 0,1810486 ! receptor metabolic process GO:0043112 37 24 0,000 0,15011291 0,18095371 ! neural crest cell development GO:0014032 39 24 0,000 0,15011291 0,18085892 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,15011291 0,18076423 ! negative regulation of cell development GO:0010721 56 24 0,000 0,15011291 0,18066964 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 0,000 0,15011291 0,18057515 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,15011291 0,18048076 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,15011291 0,18038646 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,15011291 0,18029226 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,15011291 0,18019817 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,15585736 0,18699631 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,15585736 0,18689882 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,15585736 0,18680142 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,15585736 0,18670413 GO:0006479|protein amino acid methylation, ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,15585736 0,18660694 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,15585736 0,18650985 ! peptide transport GO:0015833 43 25 0,000 0,15585736 0,18641286 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,15585736 0,18631597 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,15585736 0,18621918 ! phospholipid transport GO:0015914 35 25 0,000 0,15585736 0,1861225 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,15585736 0,18602591 ! detection of light stimulus GO:0009583 30 25 0,000 0,15585736 0,18592942 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,15585736 0,18583304 GO:0045840|positive regulation of mitosis, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,16156331 0,19253659 ! translational initiation GO:0006413 43 26 0,000 0,16156331 0,19243688 ! regulation of pH GO:0006885 36 26 0,000 0,16156331 0,19233728 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 0,000 0,16156331 0,19223778 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,16156331 0,19213838 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,16156331 0,19203908 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,16156331 0,19193989 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,16156331 0,1918408 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,16156331 0,19174181 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,16156331 0,19164292 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,16156331 0,19154414 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,16156331 0,19144545 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,16156331 0,19134687 ! regulation of coagulation GO:0050818 39 26 0,000 0,16156331 0,19124839 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,16723102 0,19785563 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,16723102 0,19775391 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,16723102 0,19765229 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,16723102 0,19755077 ! membrane docking GO:0022406 39 27 0,000 0,16723102 0,19744936 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,16723102 0,19734805 ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,16723102 0,19724685 ! acute-phase response GO:0006953 42 27 0,000 0,16723102 0,19714575 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,16723102 0,19704475 ! myofibril assembly GO:0030239 36 27 0,000 0,16723102 0,19694386 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,16723102 0,19684307 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,16723102 0,19674238 ! natural killer cell activation GO:0030101 35 27 0,000 0,16723102 0,1966418 ! lipid oxidation GO:0034440 38 27 0,000 0,16723102 0,19654131 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,16723102 0,19644094 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,16723102 0,19634066 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,16723102 0,19624049 ! gene silencing GO:0016458 41 27 0,000 0,16723102 0,19614041 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,17286074 0,20264001 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,17286074 0,20253678 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,17286074 0,20243366 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,17286074 0,20233064 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,17286074 0,20222772 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,17286074 0,20212491 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,17286074 0,20202221 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,17286074 0,20191961 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,17286074 0,20181711 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,17286074 0,20171472 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,17286074 0,20161243 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,17286074 0,20151024 ! mesoderm formation GO:0001707 46 28 0,000 0,17286074 0,20140816 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,17286074 0,20130618 ! ensheathment of neurons GO:0007272 43 28 0,000 0,17286074 0,2012043 GO:0008366|axon ensheathment, ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,17286074 0,20110253 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,17286074 0,20100086 ! neural tube formation GO:0001841 41 28 0,000 0,17286074 0,2008993 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,17286074 0,20079783 ! placenta development GO:0001890 37 28 0,000 0,17286074 0,20069647 ! regulation of innate immune response GO:0045088 38 29 0,000 0,17845272 0,20708439 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,17845272 0,20697996 ! protein targeting to membrane GO:0006612 53 29 0,000 0,17845272 0,20687564 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,17845272 0,20677142 ! mismatch repair GO:0006298 34 29 0,000 0,17845272 0,2066673 ! muscle cell development GO:0055001 38 29 0,000 0,17845272 0,20656329 ! formation of primary germ layer GO:0001704 48 29 0,000 0,17845272 0,20645939 ! telencephalon development GO:0021537 52 29 0,000 0,17845272 0,20635559 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,17845272 0,20625189 ! eye morphogenesis GO:0048592 51 29 0,000 0,17845272 0,2061483 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,17845272 0,20604481 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,18400722 0,21235153 ! collagen metabolic process GO:0032963 40 30 0,000 0,18400722 0,21224503 ! organic anion transport GO:0015711 51 30 0,000 0,18400722 0,21213865 ! cholesterol transport GO:0030301 46 30 0,000 0,18400722 0,21203236 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,18400722 0,21192619 ! spindle organization GO:0007051 37 30 0,000 0,18400722 0,21182012 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,18400722 0,21171416 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,18400722 0,2116083 ! ceramide metabolic process GO:0006672 43 30 0,000 0,18400722 0,21150255 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,18400722 0,2113969 ! adult locomotory behavior GO:0008344 47 30 0,000 0,18400722 0,21129136 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,18400722 0,21118593 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,18400722 0,2110806 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,18400722 0,21097537 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,18400722 0,21087025 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,18952447 0,2170848 ! negative regulation of secretion GO:0051048 49 31 0,000 0,18952447 0,21697675 ! mammary gland development GO:0030879 57 31 0,000 0,18952447 0,2168688 ! glial cell differentiation GO:0010001 55 31 0,000 0,18952447 0,21676096 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,18952447 0,21665322 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,18952447 0,2165456 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,18952447 0,21643808 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,18952447 0,21633066 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,18952447 0,21622336 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,18952447 0,21611616 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,18952447 0,21600906 ! RNA modification GO:0009451 40 31 0,000 0,18952447 0,21590207 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,19500474 0,2220351 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,19500474 0,22192523 ! meiosis I GO:0007127 52 32 0,000 0,19500474 0,22181548 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,19500474 0,22170583 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,19500474 0,22159629 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,19500474 0,22148686 ! peripheral nervous system development GO:0007422 53 32 0,000 0,19500474 0,22137754 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,19500474 0,22126833 ! cytokine production GO:0001816 44 32 0,000 0,19500474 0,22115922 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,19500474 0,22105022 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,19500474 0,22094133 ! vesicle localization GO:0051648 47 32 0,000 0,19500474 0,22083254 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,20044826 0,22688533 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,20044826 0,22677373 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,20044826 0,22666224 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,20044826 0,22655086 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,20044826 0,22643958 ! sister chromatid segregation GO:0000819 46 33 0,000 0,20044826 0,22632842 ! actomyosin structure organization GO:0031032 43 33 0,000 0,20044826 0,22621737 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,20044826 0,22610642 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,20044826 0,22599559 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,20044826 0,22588486 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,20044826 0,22577424 ! lipid homeostasis GO:0055088 55 33 0,000 0,20044826 0,22566373 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,20044826 0,22555332 ! regulation of proteolysis GO:0030162 50 33 0,000 0,20044826 0,22544303 ! cytokinesis GO:0000910 52 33 0,000 0,20044826 0,22533284 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,20044826 0,22522276 ! mRNA catabolic process GO:0006402 48 34 0,000 0,20585528 0,23118513 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,20585528 0,2310723 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,20585528 0,23095958 ! feeding behavior GO:0007631 45 34 0,000 0,20585528 0,23084697 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,20585528 0,23073447 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,20585528 0,23062209 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,20585528 0,23050981 ! neuron migration GO:0001764 46 34 0,000 0,20585528 0,23039764 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,20585528 0,23028558 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,20585528 0,23017362 ! polyol metabolic process GO:0019751 44 34 0,000 0,20585528 0,23006178 ! aerobic respiration GO:0009060 47 34 0,000 0,20585528 0,22995004 ! cellular response to insulin stimulus GO:0032869 52 34 0,000 0,20585528 0,22983842 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,21122604 0,23572047 ! Notch signaling pathway GO:0007219 56 35 0,000 0,21122604 0,23560616 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,21122604 0,23549195 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,21122604 0,23537786 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,21122604 0,23526387 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,21122604 0,23515 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,21122604 0,23503624 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,21122604 0,23492258 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,21122604 0,23480904 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,21122604 0,2346956 ! protein homooligomerization GO:0051260 52 35 0,000 0,21122604 0,23458228 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,21656079 0,24039084 ! organic ether metabolic process GO:0018904 46 36 0,000 0,21656079 0,24027487 ! neural tube development GO:0021915 50 36 0,000 0,21656079 0,24015902 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,21656079 0,24004328 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,21656079 0,23992766 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,21656079 0,23981214 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,22185976 0,24556181 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,22185976 0,2454437 ! ion transmembrane transport GO:0034220 56 37 0,000 0,22185976 0,2453257 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,22185976 0,24520781 ! regulation of protein secretion GO:0050708 51 37 0,000 0,22185976 0,24509003 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,22185976 0,24497237 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,22712319 0,25066379 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,22712319 0,25054357 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,22712319 0,25042346 ! maintenance of location in cell GO:0051651 69 38 0,000 0,22712319 0,25030347 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,23235132 0,25594254 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,23235132 0,25582002 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,23235132 0,25569762 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,23235132 0,25557534 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,23235132 0,25545317 ! chromatin remodeling GO:0006338 68 39 0,000 0,23235132 0,25533112 ! JNK cascade GO:0007254 54 39 0,000 0,23235132 0,25520918 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,23754438 0,26078858 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,23754438 0,26066415 ! regulation of tube size GO:0035150 60 40 0,000 0,23754438 0,26053985 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,23754438 0,26041567 ! inner ear development GO:0048839 57 40 0,000 0,23754438 0,2602916 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,23754438 0,26016765 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,23754438 0,26004382 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,23754438 0,25992011 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,2427026 0,26543794 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,2427026 0,26531178 ! glucose transport GO:0015758 52 41 0,000 0,2427026 0,26518574 ! endosome transport GO:0016197 71 41 0,000 0,2427026 0,26505982 ! striated muscle contraction GO:0006941 62 41 0,000 0,2427026 0,26493402 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,2427026 0,26480834 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,2427026 0,26468278 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,24782622 0,27014233 ! hexose transport GO:0008645 54 42 0,000 0,24782622 0,27001436 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,24782622 0,26988651 ! excretion GO:0007588 63 42 0,000 0,24782622 0,26975879 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,24782622 0,26963118 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,24782622 0,2695037 ! neuromuscular process GO:0050905 79 43 0,000 0,25291547 0,27490812 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,25291547 0,27477827 ! tRNA processing GO:0008033 49 43 0,000 0,25291547 0,27464853 ! response to insulin stimulus GO:0032868 63 43 0,000 0,25291547 0,27451892 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,25797058 0,27987374 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,25797058 0,27974179 ! glycolysis GO:0006096 53 44 0,000 0,25797058 0,27960996 ! regulation of action potential GO:0001508 71 44 0,000 0,25797058 0,27947825 ! regulation of ion transport GO:0043269 57 44 0,000 0,25797058 0,27934667 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,25797058 0,27921521 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,25797058 0,27908388 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,25797058 0,27895267 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,25797058 0,27882158 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,25797058 0,27869062 ! RNA catabolic process GO:0006401 64 45 0,000 0,26299177 0,28398172 ! positive regulation of defense response GO:0031349 59 45 0,000 0,26299177 0,28384846 ! regulation of translational initiation GO:0006446 64 45 0,000 0,26299177 0,28371532 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,26299177 0,28358231 ! cell recognition GO:0008037 58 45 0,000 0,26299177 0,28344942 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,26797926 0,2886896 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,26797926 0,28855445 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,26797926 0,28841942 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,27293329 0,29361392 ! viral infectious cycle GO:0019058 71 47 0,000 0,27293329 0,29347666 ! endocrine system development GO:0035270 83 47 0,000 0,27293329 0,29333952 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,27293329 0,29320251 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,27293329 0,29306563 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,27293329 0,29292887 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,27293329 0,29279224 ! chloride transport GO:0006821 67 48 0,000 0,27785408 0,29793211 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,27785408 0,29779328 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,27785408 0,29765458 ! gastrulation GO:0007369 73 48 0,000 0,27785408 0,297516 ! regulation of DNA replication GO:0006275 75 48 0,000 0,27785408 0,29737756 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,27785408 0,29723924 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,27785408 0,29710106 ! regulation of endocytosis GO:0030100 63 48 0,000 0,27785408 0,296963 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,27785408 0,29682507 ! regulation of angiogenesis GO:0045765 94 49 0,000 0,28274184 0,30190633 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,28274184 0,30176623 ! sensory perception of smell GO:0007608 61 49 0,000 0,28274184 0,30162626 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,28274184 0,30148643 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,28274184 0,30134672 ! RNA elongation GO:0006354 62 49 0,000 0,28274184 0,30120714 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,28274184 0,3010677 ! maintenance of location GO:0051235 84 49 0,000 0,28274184 0,30092838 ! regulation of actin filament length GO:0030832 72 50 0,000 0,28759679 0,30595404 ! skeletal muscle fiber development GO:0048741 73 50 0,000 0,28759679 0,30581259 ! membrane fusion GO:0006944 80 50 0,000 0,28759679 0,30567127 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,28759679 0,30553008 ! lipid modification GO:0030258 73 50 0,000 0,28759679 0,30538902 ! proton transport GO:0015992 75 50 0,000 0,28759679 0,3052481 ! positive regulation of secretion GO:0051047 71 51 0,000 0,29241916 0,31022328 ! hydrogen transport GO:0006818 77 51 0,000 0,29241916 0,31008026 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,29241916 0,30993736 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 0,000 0,29241916 0,3097946 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,29241916 0,30965197 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,29241916 0,30950947 ! adult behavior GO:0030534 80 51 0,000 0,29241916 0,3093671 ! transition metal ion transport GO:0000041 74 52 0,000 0,29720917 0,31429015 ! regulation of cellular component size GO:0032535 74 52 0,000 0,29720917 0,31414572 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,29720917 0,31400142 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,29720917 0,31385725 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,29720917 0,31371321 ! establishment of organelle localization GO:0051656 85 52 0,000 0,29720917 0,31356931 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,30196702 0,31844298 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,30196702 0,31829704 ! single fertilization GO:0007338 59 53 0,000 0,30196702 0,31815123 ! amino acid transport GO:0006865 84 54 0,000 0,30669293 0,32298248 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,30669293 0,32283466 ! glucose catabolic process GO:0006007 66 54 0,000 0,30669293 0,32268698 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,30669293 0,32253943 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,30669293 0,32239202 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,30669293 0,32224474 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,30669293 0,3220976 ! exocytosis GO:0006887 74 55 0,000 0,31138711 0,3268783 ! mesoderm development GO:0007498 76 55 0,000 0,31138711 0,32672918 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,31138711 0,32658019 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,31138711 0,32643134 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,31604978 0,33116833 ! carbohydrate transport GO:0008643 74 57 0,000 0,32068114 0,33586823 ! chromosome segregation GO:0007059 83 57 0,000 0,32068114 0,33571535 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,32068114 0,33556261 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,32068114 0,33541002 ! camera-type eye development GO:0043010 88 57 0,000 0,32068114 0,33525756 ! viral reproductive process GO:0022415 87 58 0,000 0,32528141 0,33991242 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,32528141 0,33975806 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,32528141 0,33960383 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,32985078 0,34421815 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,33438947 0,34879628 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,33438947 0,34863816 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,33438947 0,34848019 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,33438947 0,34832237 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,33438947 0,34816469 ! fertilization GO:0009566 68 60 0,000 0,33438947 0,34800714 ! meiosis GO:0007126 96 61 0,000 0,33889768 0,35253943 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,33889768 0,35238005 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,33889768 0,35222082 ! amine catabolic process GO:0009310 90 62 0,000 0,34337562 0,3567136 ! neurotransmitter transport GO:0006836 81 62 0,000 0,34337562 0,35655256 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,34337562 0,35639166 ! meiotic cell cycle GO:0051321 97 62 0,000 0,34337562 0,35623091 ! organelle localization GO:0051640 96 62 0,000 0,34337562 0,3560703 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,34782347 0,36052005 ! viral reproduction GO:0016032 92 63 0,000 0,34782347 0,36035765 ! regulation of lipase activity GO:0060191 109 63 0,000 0,34782347 0,3601954 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,35224146 0,36460637 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,35224146 0,36444235 ! hexose catabolic process GO:0019320 82 64 0,000 0,35224146 0,36427849 ! defense response to bacterium GO:0042742 73 65 0,000 0,35662976 0,36865099 ! activation of immune response GO:0002253 83 65 0,000 0,35662976 0,36848538 ! protein oligomerization GO:0051259 100 65 0,000 0,35662976 0,36831992 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,36098859 0,37265429 ! antigen processing and presentation GO:0019882 96 66 0,000 0,36098859 0,3724871 ! axon guidance GO:0007411 99 66 0,000 0,36098859 0,37232007 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,36098859 0,37215318 ! regulation of immune effector process GO:0002697 101 66 0,000 0,36098859 0,37198645 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,36531813 0,37627931 ! acute inflammatory response GO:0002526 92 68 0,000 0,36961859 0,38053839 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,36961859 0,38036812 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,36961859 0,38019801 ! inorganic anion transport GO:0015698 93 68 0,000 0,36961859 0,38002806 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,37389015 0,38424815 ! amine transport GO:0015837 101 70 0,000 0,37813302 0,38843499 ! regulation of catabolic process GO:0009894 106 70 0,000 0,37813302 0,38826158 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,38234737 0,39241363 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,38234737 0,3922386 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,38234737 0,39206373 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,3865334 0,39617951 ! negative regulation of transport GO:0051051 116 73 0,000 0,3906913 0,4002628 ! regulation of blood pressure GO:0008217 107 73 0,000 0,3906913 0,40008459 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,3906913 0,39990654 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,39482126 0,40395414 ! digestion GO:0007586 97 74 0,000 0,39482126 0,40377452 ! blood coagulation GO:0007596 116 75 0,000 0,39892346 0,40778843 GO:0050817|coagulation, ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,39892346 0,40760727 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,40704532 0,41572125 ! protein ubiquitination GO:0016567 125 77 0,000 0,40704532 0,41553673 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,40704532 0,41535237 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,41106536 0,41926843 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,41106536 0,41908259 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,41505836 0,42296599 ! cellular respiration GO:0045333 107 79 0,000 0,41505836 0,42277867 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,41505836 0,42259152 ! regulation of lyase activity GO:0051339 133 79 0,000 0,41505836 0,42240453 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,41505836 0,42221771 ! chromatin assembly GO:0031497 102 80 0,000 0,41902452 0,42606384 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,41902452 0,42587557 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,41902452 0,42568746 ! forebrain development GO:0030900 131 80 0,000 0,41902452 0,42549952 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,42296402 0,42931035 ! hemostasis GO:0007599 125 81 0,000 0,42296402 0,42912097 ! vitamin metabolic process GO:0006766 103 81 0,000 0,42296402 0,42893177 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,43076372 0,43664899 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of defense response GO:0031347 117 84 0,000 0,43462428 0,44036822 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,43462428 0,44017431 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,43462428 0,43998057 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,43845888 0,44366715 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,44226769 0,4473244 ! nucleosome organization GO:0034728 114 87 0,000 0,44605088 0,45095254 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,44605088 0,45075441 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,44605088 0,45055645 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,44980863 0,4541527 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,44980863 0,45395342 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,4535411 0,45751953 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,4535411 0,45731895 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,45724846 0,46085515 ! ATP metabolic process GO:0046034 137 91 0,000 0,46093088 0,46436313 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,46458853 0,46784309 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,46458853 0,46763835 ! DNA recombination GO:0006310 146 92 0,000 0,46458853 0,46743378 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,46822157 0,47088308 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,46822157 0,47067728 ! electron transport chain GO:0022900 123 94 0,000 0,47183017 0,47409759 ! carboxylic acid transport GO:0046942 147 95 0,000 0,47541448 0,47749052 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,47897467 0,48085628 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,47897467 0,48064649 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,47897467 0,48043687 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,48251091 0,48377292 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,48251091 0,48356213 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,48951214 0,49036495 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,49297746 0,49362131 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,49297746 0,49340651 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,49297746 0,49319189 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,49297746 0,49297746