pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/562-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 2,518E-09 6,059E-06 ! interphase GO:0051325 213 98 8,000 3,326E-09 4,002E-06 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 6,000 5,357E-09 4,296E-06 ! morphogenesis of a branching structure GO:0001763 111 52 6,000 1,303E-08 7,837E-06 ! regulation of bone remodeling GO:0046850 137 57 6,000 2,517E-08 1,211E-05 ! regulation of tissue remodeling GO:0034103 140 58 6,000 2,85E-08 1,143E-05 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 3,000 5,692E-08 1,956E-05 ! cell cycle arrest GO:0007050 213 100 7,000 7,557E-08 2,273E-05 ! branching morphogenesis of a tube GO:0048754 97 45 5,000 1,567E-07 4,19E-05 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 3,000 1,693E-07 4,074E-05 ! regulation of ossification GO:0030278 117 50 5,000 2,99E-07 6,541E-05 ! positive regulation of cell migration GO:0030335 126 57 5,000 6,619E-07 1,327E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 3,000 7,935E-07 1,469E-04 GO:0060675|ureteric bud morphogenesis, ! C21-steroid hormone biosynthetic process GO:0006700 23 15 3,000 1,077E-06 1,852E-04 ! positive regulation of cell motion GO:0051272 146 64 5,000 1,325E-06 2,126E-04 ! stem cell division GO:0017145 11 5 2,000 1,544E-06 2,322E-04 GO:0048103|somatic stem cell division, ! negative regulation of cell growth GO:0030308 132 67 5,000 1,741E-06 2,464E-04 ! negative regulation of cell size GO:0045792 134 69 5,000 2,072E-06 2,77E-04 ! proximal/distal pattern formation GO:0009954 32 19 3,000 3,008E-06 3,809E-04 ! neural nucleus development GO:0048857 14 6 2,000 3,076E-06 3,7E-04 ! positive regulation of ossification GO:0045778 47 20 3,000 3,745E-06 4,29E-04 ! C21-steroid hormone metabolic process GO:0008207 33 20 3,000 3,745E-06 4,095E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,745E-06 3,917E-04 ! positive regulation of bone remodeling GO:0046852 51 22 3,000 5,606E-06 5,62E-04 GO:0034105|positive regulation of tissue remodeling, ! ureteric bud development GO:0001657 43 22 3,000 5,606E-06 5,395E-04 ! negative regulation of growth GO:0045926 155 84 5,000 6,573E-06 6,082E-04 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 6,758E-06 6,022E-04 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 3,000 6,758E-06 5,807E-04 ! tube morphogenesis GO:0035239 176 86 5,000 7,535E-06 6,251E-04 ! ER overload response GO:0006983 12 8 2,000 8,544E-06 6,852E-04 ! positive regulation of growth GO:0045927 90 52 4,000 9,24E-06 7,172E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 9,573E-06 7,197E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 9,573E-06 6,979E-04 ! regulation of osteoblast differentiation GO:0045667 65 26 3,000 1,127E-05 7,972E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 1,53E-05 1,052E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 1,816E-05 1,214E-03 ! regulation of homeostatic process GO:0032844 134 62 4,000 2,203E-05 1,432E-03 ! metanephros development GO:0001656 74 32 3,000 2,642E-05 1,673E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 3,303E-05 2,038E-03 ! focal adhesion formation GO:0048041 35 12 2,000 3,303E-05 1,987E-03 ! autonomic nervous system development GO:0048483 24 12 2,000 3,303E-05 1,939E-03 ! gland morphogenesis GO:0022612 29 12 2,000 3,303E-05 1,892E-03 ! digestive tract morphogenesis GO:0048546 26 12 2,000 3,303E-05 1,848E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of cell development GO:0010720 80 36 3,000 4,255E-05 2,327E-03 ! hormone biosynthetic process GO:0042446 57 36 3,000 4,255E-05 2,275E-03 ! hair follicle morphogenesis GO:0031069 26 14 2,000 5,422E-05 2,836E-03 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 5,422E-05 2,776E-03 ! cell-matrix adhesion GO:0007160 163 75 4,000 5,551E-05 2,783E-03 ! steroid biosynthetic process GO:0006694 131 76 4,000 5,916E-05 2,905E-03 ! mesenchymal cell development GO:0014031 87 40 3,000 6,492E-05 3,124E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of bone remodeling GO:0046851 33 15 2,000 6,751E-05 3,185E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 6,751E-05 3,124E-03 ! response to reactive oxygen species GO:0000302 67 42 3,000 7,884E-05 3,579E-03 ! response to hypoxia GO:0001666 171 81 4,000 8,029E-05 3,577E-03 ! cell-substrate adhesion GO:0031589 171 81 4,000 8,029E-05 3,512E-03 ! negative regulation of tissue remodeling GO:0034104 36 16 2,000 8,276E-05 3,556E-03 ! response to oxygen levels GO:0070482 176 83 4,000 9,019E-05 3,807E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 2,000 1,001E-04 4,152E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,001E-04 4,082E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 1,001E-04 4,014E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 1,196E-04 4,719E-03 ! epidermis morphogenesis GO:0048730 40 18 2,000 1,196E-04 4,643E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,196E-04 4,569E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,196E-04 4,498E-03 ! regulation of cell adhesion GO:0030155 212 89 4,000 1,256E-04 4,65E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 1,415E-04 5,158E-03 ! cellular response to unfolded protein GO:0034620 33 19 2,000 1,415E-04 5,081E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! G1 phase GO:0051318 40 19 2,000 1,415E-04 5,007E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 1,569E-04 5,47E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,658E-04 5,699E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,658E-04 5,619E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 1,658E-04 5,541E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 1,658E-04 5,465E-03 ! epithelial tube morphogenesis GO:0060562 98 51 3,000 1,695E-04 5,511E-03 ! cartilage development GO:0051216 90 52 3,000 1,828E-04 5,866E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 1,927E-04 6,1E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 1,927E-04 6,021E-03 ! gut development GO:0048565 39 21 2,000 1,927E-04 5,943E-03 ! response to UV GO:0009411 104 53 3,000 1,969E-04 5,998E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,222E-04 6,683E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,222E-04 6,601E-03 ! aging GO:0007568 103 55 3,000 2,275E-04 6,674E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 2,545E-04 7,379E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 2,545E-04 7,291E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 2,612E-04 7,395E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,88E-04 8,058E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 2,88E-04 7,966E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,88E-04 7,875E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 1,000 2,88E-04 7,787E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,88E-04 7,7E-03 ! microvillus organization GO:0032528 7 5 1,000 2,88E-04 7,615E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 2,88E-04 7,533E-03 ! mRNA transcription GO:0009299 9 5 1,000 2,88E-04 7,452E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 2,88E-04 7,372E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,88E-04 7,295E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,88E-04 7,219E-03 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 1,000 2,88E-04 7,144E-03 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! positive regulation of organ growth GO:0046622 6 5 1,000 2,88E-04 7,072E-03 ! enteric nervous system development GO:0048484 8 5 1,000 2,88E-04 7E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 2,88E-04 6,93E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,88E-04 6,861E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 2,88E-04 6,794E-03 GO:0042634|regulation of hair cycle, ! circadian behavior GO:0048512 13 5 1,000 2,88E-04 6,728E-03 ! glial cell migration GO:0008347 11 5 1,000 2,88E-04 6,664E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 2,88E-04 6,6E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,88E-04 6,538E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,88E-04 6,477E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 2,897E-04 6,455E-03 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 2,897E-04 6,396E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 2,897E-04 6,338E-03 ! skeletal system morphogenesis GO:0048705 105 59 3,000 2,985E-04 6,47E-03 ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 2,985E-04 6,412E-03 ! kidney development GO:0001822 122 60 3,000 3,185E-04 6,781E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 3,28E-04 6,922E-03 ! molting cycle process GO:0022404 50 26 2,000 3,693E-04 7,726E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 3,693E-04 7,659E-03 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 4,138E-04 8,509E-03 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 4,138E-04 8,437E-03 ! sleep GO:0030431 13 6 1,000 4,305E-04 8,704E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 4,305E-04 8,632E-03 ! negative regulation of T cell differentiation GO:0045581 14 6 1,000 4,305E-04 8,56E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 4,305E-04 8,49E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 4,305E-04 8,421E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 4,305E-04 8,353E-03 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 4,305E-04 8,287E-03 GO:0045625|regulation of T-helper 1 cell differentiation, ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,305E-04 8,221E-03 ! embryonic limb morphogenesis GO:0030326 125 65 3,000 4,33E-04 8,203E-03 GO:0035113|embryonic appendage morphogenesis, ! cellular hormone metabolic process GO:0034754 113 67 3,000 4,861E-04 9,137E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 4,861E-04 9,066E-03 ! lung development GO:0030324 144 67 3,000 4,861E-04 8,996E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 5,143E-04 9,446E-03 ! urogenital system development GO:0001655 137 69 3,000 5,437E-04 9,91E-03 ! cell junction assembly GO:0034329 78 30 2,000 5,675E-04 0,0102668 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 5,675E-04 0,01019018 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 5,675E-04 0,01011469 ! regulation of B cell activation GO:0050864 50 30 2,000 5,675E-04 0,01004032 ! appendage morphogenesis GO:0035107 135 70 3,000 5,742E-04 0,0100845 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 3,000 5,742E-04 0,01001142 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 6,006E-04 0,01039554 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,006E-04 0,01032129 ! neuron adhesion GO:0007158 12 7 1,000 6,006E-04 0,01024809 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,006E-04 0,01017592 ! mRNA stabilization GO:0048255 18 7 1,000 6,006E-04 0,01010476 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 10 7 1,000 6,006E-04 0,01003458 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,006E-04 9,965E-03 ! rhythmic behavior GO:0007622 15 7 1,000 6,006E-04 9,897E-03 ! regulation of odontogenesis GO:0042481 13 7 1,000 6,006E-04 9,83E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 6,006E-04 9,763E-03 ! organ growth GO:0035265 15 7 1,000 6,006E-04 9,698E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 6,006E-04 9,633E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 6,006E-04 9,569E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 6,006E-04 9,506E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 6,006E-04 9,444E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 6,006E-04 9,383E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 6,006E-04 9,322E-03 ! appendage development GO:0048736 136 71 3,000 6,06E-04 9,346E-03 GO:0060173|limb development, ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 6,259E-04 9,591E-03 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of transferase activity GO:0051348 140 72 3,000 6,389E-04 9,729E-03 ! respiratory system development GO:0060541 153 72 3,000 6,389E-04 9,668E-03 ! response to hydrogen peroxide GO:0042542 50 32 2,000 6,879E-04 0,01034374 ! hindbrain development GO:0030902 61 32 2,000 6,879E-04 0,01027949 ! regulation of transcription factor activity GO:0051090 126 74 3,000 7,086E-04 0,01052442 GO:0090046|regulation of transcription regulator activity, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 7,979E-04 0,01177784 ! succinate metabolic process GO:0006105 14 8 1,000 7,979E-04 0,01170602 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,979E-04 0,01163508 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,979E-04 0,01156499 ! pigment granule organization GO:0048753 16 8 1,000 7,979E-04 0,01149574 ! regulation of pigmentation during development GO:0048070 24 8 1,000 7,979E-04 0,01142731 ! melanin metabolic process GO:0006582 15 8 1,000 7,979E-04 0,01135969 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,979E-04 0,01129287 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,979E-04 0,01122683 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,979E-04 0,01116156 ! response to UV-B GO:0010224 16 8 1,000 7,979E-04 0,01109704 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 7,979E-04 0,01103326 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 7,979E-04 0,01097022 ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 7,979E-04 0,01090789 ! positive regulation of epidermis development GO:0045684 13 8 1,000 7,979E-04 0,01084626 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 1,000 7,979E-04 0,01078533 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 9,062E-04 0,01218014 ! cell junction organization GO:0034330 86 36 2,000 9,746E-04 0,01302738 ! embryonic organ development GO:0048568 57 36 2,000 9,746E-04 0,0129554 ! negative regulation of cell activation GO:0050866 65 36 2,000 9,746E-04 0,01288422 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,022E-03 0,01344002 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,022E-03 0,01336698 ! T cell selection GO:0045058 23 9 1,000 1,022E-03 0,01329472 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,022E-03 0,01322325 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,022E-03 0,01315253 GO:0006600|creatine metabolic process, ! behavioral fear response GO:0001662 22 9 1,000 1,022E-03 0,01308257 GO:0002209|behavioral defense response, ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,022E-03 0,01301335 ! response to amine stimulus GO:0014075 13 9 1,000 1,022E-03 0,01294486 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,022E-03 0,01287709 ! induction of an organ GO:0001759 14 9 1,000 1,022E-03 0,01281002 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,022E-03 0,01274365 ! negative regulation of lymphocyte differentiation GO:0045620 19 9 1,000 1,022E-03 0,01267796 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,022E-03 0,01261294 ! response to drug GO:0042493 143 82 3,000 1,042E-03 0,01278761 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,056E-03 0,01290227 ! regulation of protein stability GO:0031647 73 37 2,000 1,056E-03 0,0128371 ! regulation of ligase activity GO:0051340 142 84 3,000 1,14E-03 0,01377848 ! nucleus organization GO:0006997 67 38 2,000 1,142E-03 0,01374353 ! mitochondrion organization GO:0007005 148 86 3,000 1,244E-03 0,01488835 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,273E-03 0,01516574 ! regulation of phosphatase activity GO:0010921 28 10 1,000 1,273E-03 0,01509103 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 1,273E-03 0,01501706 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,273E-03 0,0149438 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,273E-03 0,01487126 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,273E-03 0,01479942 ! lung alveolus development GO:0048286 26 10 1,000 1,273E-03 0,01472827 ! B cell proliferation GO:0042100 18 10 1,000 1,273E-03 0,0146578 ! phagocytosis, engulfment GO:0006911 28 10 1,000 1,273E-03 0,014588 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 1,273E-03 0,01451886 ! regulation of bone resorption GO:0045124 25 10 1,000 1,273E-03 0,01445038 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,273E-03 0,01438253 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,273E-03 0,01431533 ! salivary gland development GO:0007431 27 10 1,000 1,273E-03 0,01424874 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,273E-03 0,01418278 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,273E-03 0,01411742 ! oocyte development GO:0048599 17 10 1,000 1,273E-03 0,01405266 ! response to nicotine GO:0035094 20 10 1,000 1,273E-03 0,01398849 ! negative regulation of binding GO:0051100 72 40 2,000 1,327E-03 0,01451737 ! regulation of DNA binding GO:0051101 155 88 3,000 1,354E-03 0,01474571 ! gliogenesis GO:0042063 88 41 2,000 1,427E-03 0,01546107 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,427E-03 0,01539174 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,53E-03 0,01643658 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 1,53E-03 0,01636353 ! response to protein stimulus GO:0051789 149 91 3,000 1,533E-03 0,01632095 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,551E-03 0,01643592 ! blood vessel remodeling GO:0001974 29 11 1,000 1,551E-03 0,01636383 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,551E-03 0,01629237 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,551E-03 0,01622154 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,551E-03 0,01615131 ! chondrocyte differentiation GO:0002062 24 11 1,000 1,551E-03 0,0160817 ! negative regulation of ossification GO:0030279 26 11 1,000 1,551E-03 0,01601268 ! regulation of organ growth GO:0046620 13 11 1,000 1,551E-03 0,01594425 ! DNA methylation GO:0006306 19 11 1,000 1,551E-03 0,0158764 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,551E-03 0,01580912 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 1,551E-03 0,01574242 ! oocyte differentiation GO:0009994 18 11 1,000 1,551E-03 0,01567627 ! thymus development GO:0048538 27 11 1,000 1,551E-03 0,01561068 ! embryonic gut development GO:0048566 15 11 1,000 1,551E-03 0,01554564 ! cardiac cell differentiation GO:0035051 31 11 1,000 1,551E-03 0,01548113 ! developmental induction GO:0031128 19 11 1,000 1,551E-03 0,01541716 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,639E-03 0,01622348 ! female pregnancy GO:0007565 164 94 3,000 1,727E-03 0,01703369 ! cartilage condensation GO:0001502 20 12 1,000 1,854E-03 0,01820918 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 1,854E-03 0,01813515 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,854E-03 0,01806173 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,854E-03 0,0179889 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,854E-03 0,01791666 ! fear response GO:0042596 26 12 1,000 1,854E-03 0,01784499 ! cranial nerve development GO:0021545 20 12 1,000 1,854E-03 0,0177739 ! histone acetylation GO:0016573 26 12 1,000 1,854E-03 0,01770336 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,854E-03 0,01763339 ! T cell homeostasis GO:0043029 25 12 1,000 1,854E-03 0,01756397 ! spleen development GO:0048536 22 12 1,000 1,854E-03 0,01749509 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,854E-03 0,01742675 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,854E-03 0,01735894 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,869E-03 0,01743128 ! cell growth GO:0016049 84 45 2,000 1,869E-03 0,01736397 ! hormone metabolic process GO:0042445 157 97 3,000 1,938E-03 0,01793675 ! regulation of protein localization GO:0032880 176 97 3,000 1,938E-03 0,01786802 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,992E-03 0,0182903 ! pigmentation GO:0043473 100 46 2,000 1,992E-03 0,01822076 ! positive regulation of protein transport GO:0051222 72 46 2,000 1,992E-03 0,01815174 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 2,184E-03 0,01982518 ! exocrine system development GO:0035272 32 13 1,000 2,184E-03 0,01975065 ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 2,184E-03 0,01967667 ! regulation of epidermis development GO:0045682 19 13 1,000 2,184E-03 0,01960325 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 1,000 2,184E-03 0,01953038 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,184E-03 0,01945805 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,251E-03 0,01998922 ! mitochondrial transport GO:0006839 82 48 2,000 2,251E-03 0,01991573 ! cellular component disassembly GO:0022411 86 48 2,000 2,251E-03 0,01984278 ! activation of caspase activity GO:0006919 84 48 2,000 2,251E-03 0,01977036 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,251E-03 0,01969847 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,251E-03 0,0196271 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,538E-03 0,02204888 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 2,538E-03 0,02196957 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 1,000 2,538E-03 0,02189083 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 2,538E-03 0,02181265 ! response to gamma radiation GO:0010332 28 14 1,000 2,538E-03 0,02173502 ! positive regulation of bone mineralization GO:0030501 29 14 1,000 2,538E-03 0,02165795 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 2,538E-03 0,02158142 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 2,538E-03 0,02150542 ! regulation of RNA stability GO:0043487 32 14 1,000 2,538E-03 0,02142997 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,679E-03 0,02253696 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 2,919E-03 0,0244675 ! positive regulation of cell size GO:0045793 27 15 1,000 2,919E-03 0,02438255 ! heterophilic cell adhesion GO:0007157 39 15 1,000 2,919E-03 0,02429818 ! positive regulation of biomineral formation GO:0070169 30 15 1,000 2,919E-03 0,02421439 ! regulation of T-helper cell differentiation GO:0045622 26 15 1,000 2,919E-03 0,02413118 ! dopamine metabolic process GO:0042417 35 15 1,000 2,919E-03 0,02404854 ! lymphocyte homeostasis GO:0002260 30 15 1,000 2,919E-03 0,02396646 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 1,000 2,919E-03 0,02388494 ! regulation of neuron apoptosis GO:0043523 100 53 2,000 2,99E-03 0,02438518 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,322E-03 0,02700314 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 97 55 2,000 3,322E-03 0,02691223 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 3,322E-03 0,02682192 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,324E-03 0,02674547 ! regulation of dephosphorylation GO:0035303 43 16 1,000 3,324E-03 0,02665632 ! negative regulation of immune response GO:0050777 35 16 1,000 3,324E-03 0,02656776 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,324E-03 0,02647979 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 1,000 3,324E-03 0,02639239 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,324E-03 0,02630558 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,324E-03 0,02621933 ! defense response to virus GO:0051607 37 16 1,000 3,324E-03 0,02613365 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,676E-03 0,02880965 ! metencephalon development GO:0022037 30 17 1,000 3,754E-03 0,02932155 ! regulation of viral genome replication GO:0045069 28 17 1,000 3,754E-03 0,02922666 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,754E-03 0,02913238 ! regulation of protein binding GO:0043393 33 17 1,000 3,754E-03 0,02903871 ! neutrophil chemotaxis GO:0030593 27 17 1,000 3,754E-03 0,02894564 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 3,754E-03 0,02885316 ! DNA catabolic process GO:0006308 86 59 2,000 4,052E-03 0,0310495 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 4,208E-03 0,03213948 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 4,208E-03 0,03203778 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 4,208E-03 0,03193671 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 4,208E-03 0,03183628 ! nerve development GO:0021675 28 18 1,000 4,208E-03 0,03173648 ! ear development GO:0043583 103 62 2,000 4,659E-03 0,03502867 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,686E-03 0,03512441 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 4,686E-03 0,03501533 ! cellular pigmentation GO:0033059 36 19 1,000 4,686E-03 0,03490692 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 4,686E-03 0,03479918 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 4,686E-03 0,03469211 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,188E-03 0,03829257 ! developmental maturation GO:0021700 116 66 2,000 5,549E-03 0,04082804 ! ovarian follicle development GO:0001541 35 21 1,000 5,714E-03 0,04191652 ! cell aging GO:0007569 44 21 1,000 5,714E-03 0,04178912 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 5,714E-03 0,04166248 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 5,714E-03 0,04153661 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 5,714E-03 0,0414115 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 5,714E-03 0,04128714 ! oogenesis GO:0048477 36 21 1,000 5,714E-03 0,04116353 ! DNA modification GO:0006304 34 21 1,000 5,714E-03 0,04104065 ! positive regulation of locomotion GO:0040017 39 21 1,000 5,714E-03 0,04091851 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 1,000 5,714E-03 0,04079709 ! response to cytokine stimulus GO:0034097 63 21 1,000 5,714E-03 0,04067639 ! homeostasis of number of cells GO:0048872 114 67 2,000 5,786E-03 0,04106716 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 5,786E-03 0,04094637 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 6,03E-03 0,0425431 ! regulation of chemotaxis GO:0050920 40 22 1,000 6,264E-03 0,04406437 ! renal system process GO:0003014 41 22 1,000 6,264E-03 0,0439359 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 6,264E-03 0,04380818 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,264E-03 0,0436812 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 6,264E-03 0,04355496 ! regeneration GO:0031099 41 22 1,000 6,264E-03 0,04342944 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 6,264E-03 0,04330464 ! cell cycle checkpoint GO:0000075 137 69 2,000 6,279E-03 0,04328698 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 6,279E-03 0,0431633 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 6,836E-03 0,04685735 ! response to ethanol GO:0045471 46 23 1,000 6,836E-03 0,04672423 ! regulation of viral reproduction GO:0050792 38 23 1,000 6,836E-03 0,04659187 ! regulation of bone mineralization GO:0030500 49 23 1,000 6,836E-03 0,04646025 ! regulation of caspase activity GO:0043281 122 72 2,000 7,064E-03 0,04787351 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 7,064E-03 0,04773903 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 7,064E-03 0,04760531 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 7,064E-03 0,04747233 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 7,431E-03 0,04980147 ! multicellular organismal response to stress GO:0033555 49 24 1,000 7,431E-03 0,04966314 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 7,431E-03 0,04952556 ! regulation of behavior GO:0050795 43 24 1,000 7,431E-03 0,04938875 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 7,431E-03 0,0492527 ! lymphocyte proliferation GO:0046651 48 24 1,000 7,431E-03 0,04911739 ! leukocyte homeostasis GO:0001776 44 24 1,000 7,431E-03 0,04898282 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 7,618E-03 0,05007637 ! rhythmic process GO:0048511 128 75 2,000 7,904E-03 0,05181713 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 8,049E-03 0,0526217 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 8,049E-03 0,0524791 ! vasculogenesis GO:0001570 46 25 1,000 8,049E-03 0,05233726 ! osteoblast differentiation GO:0001649 60 25 1,000 8,049E-03 0,05219619 ! regulation of biomineral formation GO:0070167 51 25 1,000 8,049E-03 0,05205588 ! somitogenesis GO:0001756 43 25 1,000 8,049E-03 0,05191632 ! liver development GO:0001889 53 25 1,000 8,049E-03 0,05177751 ! positive regulation of ligase activity GO:0051351 124 77 2,000 8,495E-03 0,05450706 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 8,495E-03 0,05436209 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 8,688E-03 0,05544956 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 8,688E-03 0,05530286 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 8,688E-03 0,05515695 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 8,688E-03 0,0550118 ! cellular response to oxidative stress GO:0034599 39 26 1,000 8,688E-03 0,05486741 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 8,688E-03 0,05472378 ! leukocyte proliferation GO:0070661 52 26 1,000 8,688E-03 0,05458089 GO:0032943|mononuclear cell proliferation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 9,112E-03 0,05709477 ! activation of protein kinase activity GO:0032147 147 79 2,000 9,112E-03 0,05694647 ! regulation of peptidase activity GO:0052547 134 79 2,000 9,112E-03 0,05679894 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 9,112E-03 0,05665217 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 9,35E-03 0,05798247 ! protein amino acid acylation GO:0043543 55 27 1,000 9,35E-03 0,05783341 ! fat cell differentiation GO:0045444 50 27 1,000 9,35E-03 0,05768512 ! mitochondrial membrane organization GO:0007006 57 27 1,000 9,35E-03 0,05753759 ! male gonad development GO:0008584 44 27 1,000 9,35E-03 0,05739081 ! response to toxin GO:0009636 47 27 1,000 9,35E-03 0,05724478 ! regulation of chromosome organization GO:0033044 42 27 1,000 9,35E-03 0,05709949 ! glutathione metabolic process GO:0006749 39 27 1,000 9,35E-03 0,05695493 ! response to metal ion GO:0010038 140 80 2,000 9,43E-03 0,05729683 ! protein import into nucleus GO:0006606 158 80 2,000 9,43E-03 0,05715251 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 9,755E-03 0,0589702 GO:0045937|positive regulation of phosphate metabolic process, ! intracellular protein transmembrane transport GO:0065002 153 81 2,000 9,755E-03 0,0588224 ! nuclear import GO:0051170 161 81 2,000 9,755E-03 0,05867535 ! circadian rhythm GO:0007623 50 28 1,000 0,01003422 0,06020529 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01003422 0,06005553 ! synaptogenesis GO:0007416 42 28 1,000 0,01003422 0,05990651 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01003422 0,05975822 ! response to nutrient GO:0007584 125 82 2,000 0,01008572 0,05991662 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,0107395 0,06364347 ! catechol metabolic process GO:0009712 54 29 1,000 0,0107395 0,0634871 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 55 29 1,000 0,0107395 0,06333149 ! sterol biosynthetic process GO:0016126 52 29 1,000 0,0107395 0,06317665 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,0107395 0,06302256 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,0107395 0,06286922 ! tissue homeostasis GO:0001894 48 29 1,000 0,0107395 0,06271662 GO:0048871|multicellular organismal homeostasis, ! response to unfolded protein GO:0006986 131 85 2,000 0,01111723 0,06476527 ! one-carbon metabolic process GO:0006730 154 85 2,000 0,01111723 0,06460883 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01111723 0,06445315 GO:0002696|positive regulation of leukocyte activation, ! phenol metabolic process GO:0018958 55 30 1,000 0,01146607 0,0663158 ! response to heat GO:0009408 50 30 1,000 0,01146607 0,06615677 ! response to inorganic substance GO:0010035 153 86 2,000 0,0114741 0,06604471 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01183752 0,06797394 ! regulation of protein transport GO:0051223 154 87 2,000 0,01183752 0,0678121 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01220751 0,06976551 ! gland development GO:0048732 206 88 2,000 0,01220751 0,06960019 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01221368 0,06947069 ! ovulation cycle process GO:0022602 49 31 1,000 0,01221368 0,06930685 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01221368 0,06914377 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01221368 0,06898146 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01258409 0,07090709 ! ossification GO:0001503 188 90 2,000 0,01296728 0,07289548 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01296728 0,07272556 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01298206 0,07263917 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01298206 0,07247064 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01298206 0,07230288 ! ovulation cycle GO:0042698 51 32 1,000 0,01298206 0,0721359 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01298206 0,07196969 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01298206 0,07180424 ! bone development GO:0060348 189 91 2,000 0,01335708 0,07370901 ! post-embryonic development GO:0009791 69 33 1,000 0,01377099 0,07581924 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01377099 0,07564614 ! cell fate specification GO:0001708 52 33 1,000 0,01377099 0,07547382 ! leukocyte chemotaxis GO:0030595 50 33 1,000 0,01377099 0,07530229 GO:0060326|cell chemotaxis, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,01415661 0,07723536 GO:0010498|proteasomal protein catabolic process, ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01415661 0,07706062 ! transcription initiation GO:0006352 153 94 2,000 0,01456636 0,0791121 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01456636 0,07893392 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01458022 0,07883149 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01458022 0,07865474 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 0,01458022 0,07847878 ! mRNA transport GO:0051028 169 96 2,000 0,01540591 0,08273797 ! regulation of muscle development GO:0048634 70 35 1,000 0,01540951 0,08257302 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01540951 0,08238952 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01540951 0,08220684 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01540951 0,08202497 ! odontogenesis GO:0042476 66 35 1,000 0,01540951 0,0818439 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,01540951 0,08166363 ! female gonad development GO:0008585 58 35 1,000 0,01540951 0,08148414 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01540951 0,08130545 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01625862 0,08559792 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01625862 0,08541102 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,0167155 0,08761979 GO:0060538|skeletal muscle organ development, ! tissue remodeling GO:0048771 76 37 1,000 0,01712732 0,08958333 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01712732 0,08938901 ! pigment metabolic process GO:0042440 80 37 1,000 0,01712732 0,08919553 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01801537 0,09361767 GO:0046660|female sex differentiation, ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01801537 0,09341591 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01801537 0,09321501 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01801537 0,09301498 ! glucan metabolic process GO:0044042 62 38 1,000 0,01801537 0,0928158 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,01892254 0,09728126 ! ear morphogenesis GO:0042471 60 39 1,000 0,01892254 0,09707383 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01892254 0,09686729 ! segmentation GO:0035282 67 39 1,000 0,01892254 0,09666163 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,0198486 0,10117738 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,0198486 0,10096347 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02079331 0,10554581 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02079331 0,10532361 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02079331 0,10510234 ! T cell differentiation GO:0030217 81 41 1,000 0,02079331 0,104882 ! female gamete generation GO:0007292 61 41 1,000 0,02079331 0,10466259 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02079331 0,10444408 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02175647 0,1090543 GO:0090047|positive regulation of transcription regulator activity, ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02273783 0,11373643 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02273783 0,11350046 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02273783 0,11326547 ! phagocytosis GO:0006909 90 43 1,000 0,02273783 0,11303145 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02373718 0,11775599 ! male sex differentiation GO:0046661 76 44 1,000 0,02373718 0,1175137 ! biopolymer methylation GO:0043414 84 44 1,000 0,02373718 0,11727239 ! B cell differentiation GO:0030183 107 44 1,000 0,02373718 0,11703208 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 1,000 0,02373718 0,11679275 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02373718 0,1165544 ! developmental growth GO:0048589 82 44 1,000 0,02373718 0,11631702 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,0247543 0,12105455 ! leukocyte migration GO:0050900 68 45 1,000 0,0247543 0,120809 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,0247543 0,12056445 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02578896 0,12534997 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02578896 0,12509725 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02677155 0,12960229 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02677155 0,12934205 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02677155 0,12908285 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02677155 0,12882468 ! neuron fate determination GO:0048664 7 5 0,000 0,02677155 0,12856754 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02677155 0,12831143 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02677155 0,12805634 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02677155 0,12780226 ! polyol transport GO:0015791 12 5 0,000 0,02677155 0,12754919 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02677155 0,12729711 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02677155 0,12704604 ! response to superoxide GO:0000303 10 5 0,000 0,02677155 0,12679594 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02677155 0,12654684 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02677155 0,12629871 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02677155 0,12605155 ! female meiosis GO:0007143 7 5 0,000 0,02677155 0,12580535 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02677155 0,12556012 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02677155 0,12531584 ! cobalt ion transport GO:0006824 11 5 0,000 0,02677155 0,1250725 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02677155 0,12483012 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02677155 0,12458867 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02677155 0,12434815 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02677155 0,12410855 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02677155 0,12386988 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02677155 0,12363213 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02677155 0,12339529 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02677155 0,12315935 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02677155 0,12292431 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02677155 0,12269017 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02677155 0,12245692 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02677155 0,12222455 ! negative chemotaxis GO:0050919 14 5 0,000 0,02677155 0,12199307 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02677155 0,12176246 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02677155 0,12153272 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02677155 0,12130384 ! behavioral response to pain GO:0048266 9 5 0,000 0,02677155 0,12107583 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02677155 0,12084867 ! Notch receptor processing GO:0007220 8 5 0,000 0,02677155 0,12062236 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02677155 0,1203969 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02677155 0,12017228 ! micturition GO:0060073 9 5 0,000 0,02677155 0,11994849 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02677155 0,11972554 ! copulation GO:0007620 9 5 0,000 0,02677155 0,11950341 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02677155 0,11928211 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02677155 0,11906163 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02677155 0,11884196 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02677155 0,11862309 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02677155 0,11840504 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02677155 0,11818778 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02677155 0,11797132 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02677155 0,11775565 ! grooming behavior GO:0007625 6 5 0,000 0,02677155 0,11754077 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02677155 0,11732667 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02677155 0,11711335 ! response to protozoan GO:0001562 10 5 0,000 0,02677155 0,1169008 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02677155 0,11668902 ! lymph vessel development GO:0001945 10 5 0,000 0,02677155 0,11647801 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02677155 0,11626776 ! endochondral ossification GO:0001958 16 5 0,000 0,02677155 0,11605827 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02677155 0,11584953 ! parathyroid gland development GO:0060017 13 5 0,000 0,02677155 0,11564154 ! anagen GO:0042640 6 5 0,000 0,02677155 0,1154343 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02677155 0,1152278 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02677155 0,11502204 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02677155 0,11481701 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02677155 0,1146127 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02677155 0,11440913 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02677155 0,11420628 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02677155 0,11400414 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02677155 0,11380272 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02677155 0,11360201 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02677155 0,11340201 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02677155 0,11320271 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02677155 0,11300411 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02677155 0,1128062 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02677155 0,11260899 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02677155 0,11241246 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02677155 0,11221662 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02677155 0,11202146 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02677155 0,11182698 ! histidine catabolic process GO:0006548 6 5 0,000 0,02677155 0,11163317 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02677155 0,11144003 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02677155 0,11124756 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02677155 0,11105576 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02677155 0,11086461 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02677155 0,11067412 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02677155 0,11048429 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02677155 0,1102951 ! polyol catabolic process GO:0046174 7 5 0,000 0,02677155 0,11010656 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02677155 0,10991867 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02677155 0,10973141 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02677155 0,1095448 ! muscle cell migration GO:0014812 8 5 0,000 0,02677155 0,10935881 ! mitochondrial fission GO:0000266 8 5 0,000 0,02677155 0,10917346 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02677155 0,10898873 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02677155 0,10880463 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02677155 0,10862115 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02677155 0,10843828 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02677155 0,10825603 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02677155 0,1080744 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02677155 0,10789337 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02677155 0,10771294 ! response to food GO:0032094 6 5 0,000 0,02677155 0,10753312 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02677155 0,1073539 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02677155 0,10717527 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02677155 0,10699724 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02677155 0,1068198 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02677155 0,10664295 ! forebrain neuron development GO:0021884 13 5 0,000 0,02677155 0,10646668 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02677155 0,10629099 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02677155 0,10611588 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02677155 0,10594135 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02677155 0,10576739 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02677155 0,105594 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02677155 0,10542118 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02677155 0,10524892 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02677155 0,10507723 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02677155 0,10490609 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02677155 0,10473551 ! basic amino acid transport GO:0015802 11 5 0,000 0,02677155 0,10456549 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02677155 0,10439601 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02677155 0,10422709 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02677155 0,10405871 ! depyrimidination GO:0045008 10 5 0,000 0,02677155 0,10389087 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02677155 0,10372357 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02677155 0,10355682 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02677155 0,10339059 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02677155 0,1032249 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02677155 0,10305974 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02677155 0,10289511 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02677155 0,102731 ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02677155 0,10256742 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02677155 0,10240436 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02677155 0,10224181 ! response to arsenic GO:0046685 10 5 0,000 0,02677155 0,10207978 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02677155 0,10191826 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02677155 0,10175725 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02677155 0,10159675 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02677155 0,10143676 ! response to cadmium ion GO:0046686 7 5 0,000 0,02677155 0,10127726 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02677155 0,10111827 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02677155 0,10095978 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02677155 0,10080178 ! decidualization GO:0046697 11 5 0,000 0,02677155 0,10064428 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02677155 0,10048727 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02677155 0,10033075 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02677155 0,10017471 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02677155 0,10001916 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02677155 0,09986409 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02677155 0,0997095 ! neural tube patterning GO:0021532 7 5 0,000 0,02677155 0,09955539 ! embryonic cleavage GO:0040016 6 5 0,000 0,02677155 0,09940176 ! peroxisome fission GO:0016559 5 5 0,000 0,02677155 0,0992486 ! histone demethylation GO:0016577 10 5 0,000 0,02677155 0,09909591 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02677155 0,09894369 ! mitotic recombination GO:0006312 9 5 0,000 0,02677155 0,09879193 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02677155 0,09864064 ! metaphase plate congression GO:0051310 7 5 0,000 0,02677155 0,09848982 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02677155 0,09833945 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02677155 0,09818954 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02677155 0,09804009 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02677155 0,09789109 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02677155 0,09774255 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02677155 0,09759445 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02677155 0,09744681 ! plasminogen activation GO:0031639 5 5 0,000 0,02677155 0,09729961 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02677155 0,09715285 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02677155 0,09700654 ! metaphase GO:0051323 8 5 0,000 0,02677155 0,09686066 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02677155 0,09671523 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02677155 0,09657022 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02677155 0,09642566 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02677155 0,09628152 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02677155 0,09613782 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02677155 0,09599455 ! response to redox state GO:0051775 5 5 0,000 0,02677155 0,0958517 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02677155 0,09570927 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02677155 0,09556727 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02677155 0,09542569 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02677155 0,09528453 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02677155 0,09514378 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02677155 0,09500345 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02677155 0,09486353 GO:0033015|tetrapyrrole catabolic process, ! striatum development GO:0021756 9 5 0,000 0,02677155 0,09472403 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02677155 0,09458493 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02677155 0,09444625 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02677155 0,09430796 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02677155 0,09417009 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02677155 0,09403261 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02677155 0,09389554 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02677155 0,09375886 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02677155 0,09362259 ! neuroprotection GO:0043526 6 5 0,000 0,02677155 0,09348671 ! neural plate development GO:0001840 8 5 0,000 0,02677155 0,09335122 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02677155 0,09321612 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02677155 0,09308142 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02677155 0,0929471 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02677155 0,09281317 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02677155 0,09267963 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02677155 0,09254647 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02677155 0,09241369 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02677155 0,09228129 ! spindle assembly GO:0051225 6 5 0,000 0,02677155 0,09214927 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02677155 0,09201763 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02677155 0,09188636 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02677155 0,09175547 ! drug metabolic process GO:0017144 6 5 0,000 0,02677155 0,09162495 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02677155 0,0914948 ! organ regeneration GO:0031100 7 5 0,000 0,02677155 0,09136502 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02677155 0,09123561 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02677155 0,09110656 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02677155 0,09097788 ! response to calcium ion GO:0051592 81 47 1,000 0,02684095 0,09108509 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02684095 0,0909568 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02684095 0,09082888 ! regulation of adaptive immune response GO:0002819 84 47 1,000 0,02684095 0,09070131 ! methylation GO:0032259 90 47 1,000 0,02684095 0,0905741 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,02791006 0,09404986 ! peptide metabolic process GO:0006518 76 49 1,000 0,02899607 0,09757278 ! response to temperature stimulus GO:0009266 76 49 1,000 0,02899607 0,0974365 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,02899607 0,09730061 ! histone modification GO:0016570 91 50 1,000 0,03009876 0,1008602 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03009876 0,10071993 ! positive regulation of binding GO:0051099 78 51 1,000 0,03121794 0,10431995 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,03121794 0,10417526 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03121794 0,10403097 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03121794 0,10388709 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,03121794 0,1037436 ! vesicle organization GO:0016050 107 51 1,000 0,03121794 0,1036005 ! regulation of cell shape GO:0008360 125 51 1,000 0,03121794 0,1034578 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03203975 0,10603528 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03203975 0,10588962 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03203975 0,10574437 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03203975 0,10559951 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03203975 0,10545505 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03203975 0,10531099 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03203975 0,10516732 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03203975 0,10502404 ! response to oxygen radical GO:0000305 11 6 0,000 0,03203975 0,10488115 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03203975 0,10473865 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03203975 0,10459653 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03203975 0,1044548 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03203975 0,10431346 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03203975 0,10417249 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03203975 0,10403191 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03203975 0,10389171 ! forebrain regionalization GO:0021871 8 6 0,000 0,03203975 0,10375188 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03203975 0,10361243 ! male meiosis GO:0007140 7 6 0,000 0,03203975 0,10347335 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03203975 0,10333464 ! response to zinc ion GO:0010043 9 6 0,000 0,03203975 0,10319631 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03203975 0,10305835 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03203975 0,10292075 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03203975 0,10278353 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03203975 0,10264666 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03203975 0,10251017 ! malate metabolic process GO:0006108 11 6 0,000 0,03203975 0,10237403 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03203975 0,10223826 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03203975 0,10210284 ! protein refolding GO:0042026 15 6 0,000 0,03203975 0,10196778 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03203975 0,10183308 ! opsonization GO:0008228 8 6 0,000 0,03203975 0,10169874 ! mating behavior GO:0007617 7 6 0,000 0,03203975 0,10156475 ! neuron remodeling GO:0016322 15 6 0,000 0,03203975 0,10143111 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03203975 0,10129783 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03203975 0,10116489 ! equilibrioception GO:0050957 14 6 0,000 0,03203975 0,1010323 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03203975 0,10090006 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03203975 0,10076816 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03203975 0,10063661 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03203975 0,1005054 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03203975 0,10037454 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03203975 0,10024401 ! toxin metabolic process GO:0009404 11 6 0,000 0,03203975 0,10011382 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03203975 0,09998398 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03203975 0,09985446 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03203975 0,09972528 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03203975 0,09959644 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03203975 0,09946793 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03203975 0,09933975 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03203975 0,0992119 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03203975 0,09908438 ! thymic T cell selection GO:0045061 12 6 0,000 0,03203975 0,09895718 ! protein lipoylation GO:0009249 10 6 0,000 0,03203975 0,09883031 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03203975 0,09870377 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03203975 0,09857755 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03203975 0,09845165 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03203975 0,09832608 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03203975 0,09820082 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03203975 0,09807588 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03203975 0,09795126 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03203975 0,09782696 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03203975 0,09770297 ! hyperosmotic response GO:0006972 9 6 0,000 0,03203975 0,0975793 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03203975 0,09745594 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03203975 0,09733289 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03203975 0,09721015 ! urea metabolic process GO:0019627 7 6 0,000 0,03203975 0,09708771 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03203975 0,09696559 ! neutrophil activation GO:0042119 8 6 0,000 0,03203975 0,09684378 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03203975 0,09672226 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03203975 0,09660106 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03203975 0,09648016 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03203975 0,09635956 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03203975 0,09623926 ! neuron apoptosis GO:0051402 9 6 0,000 0,03203975 0,09611926 ! nucleoside salvage GO:0043174 9 6 0,000 0,03203975 0,09599956 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03203975 0,09588016 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03203975 0,09576105 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03203975 0,09564224 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03203975 0,09552372 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03203975 0,0954055 ! carnitine transport GO:0015879 10 6 0,000 0,03203975 0,09528757 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03203975 0,09516993 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03203975 0,09505258 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03203975 0,09493552 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03203975 0,09481875 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03203975 0,09470227 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03203975 0,09458607 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03203975 0,09447015 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03203975 0,09435452 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03203975 0,09423917 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03203975 0,09412411 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03203975 0,09400932 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03203975 0,09389482 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03203975 0,09378059 ! response to UV-C GO:0010225 11 6 0,000 0,03203975 0,09366664 ! astrocyte development GO:0014002 15 6 0,000 0,03203975 0,09355297 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03203975 0,09343957 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03203975 0,09332645 ! interaction with symbiont GO:0051702 13 6 0,000 0,03203975 0,0932136 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03203975 0,09310102 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03203975 0,09298872 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03203975 0,09287668 ! response to copper ion GO:0046688 10 6 0,000 0,03203975 0,09276492 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03203975 0,09265342 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03203975 0,09254219 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03203975 0,09243123 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03203975 0,09232053 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03203975 0,0922101 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03203975 0,09209993 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03203975 0,09199003 ! hair follicle maturation GO:0048820 7 6 0,000 0,03203975 0,09188039 ! Schwann cell development GO:0014044 15 6 0,000 0,03203975 0,09177101 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03203975 0,09166188 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03203975 0,09155302 ! subpallium development GO:0021544 10 6 0,000 0,03203975 0,09144442 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03203975 0,09133607 ! histone ubiquitination GO:0016574 8 6 0,000 0,03203975 0,09122798 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03203975 0,09112015 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03203975 0,09101257 ! G2 phase GO:0051319 16 6 0,000 0,03203975 0,09090524 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03203975 0,09079817 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03203975 0,09069135 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03203975 0,09058478 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03203975 0,09047846 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03203975 0,09037239 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03203975 0,09026656 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03203975 0,09016099 ! receptor internalization GO:0031623 10 6 0,000 0,03203975 0,09005566 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03203975 0,08995058 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03203975 0,08984574 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03203975 0,08974115 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,03203975 0,0896368 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03203975 0,08953269 ! protein destabilization GO:0031648 9 6 0,000 0,03203975 0,08942882 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03203975 0,0893252 ! regulation of viral transcription GO:0046782 10 6 0,000 0,03203975 0,08922181 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03203975 0,08911866 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03203975 0,08901576 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03203975 0,08891309 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03203975 0,08881065 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03203975 0,08870845 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03203975 0,08860649 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03203975 0,08850476 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03203975 0,08840326 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03203975 0,088302 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03203975 0,08820097 ! catecholamine transport GO:0051937 9 6 0,000 0,03203975 0,08810017 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03203975 0,08799959 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03203975 0,08789925 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03203975 0,08779914 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03203975 0,08769925 ! maternal placenta development GO:0001893 12 6 0,000 0,03203975 0,0875996 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03203975 0,08750016 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03203975 0,08740096 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03203975 0,08730198 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03203975 0,08720322 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03203975 0,08710468 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03203975 0,08700637 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03235339 0,08775902 ! amino acid activation GO:0043038 92 52 1,000 0,03235339 0,08766019 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,03235339 0,08756158 ! cell maturation GO:0048469 100 53 1,000 0,0335049 0,09057616 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,03467227 0,09362679 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03585529 0,09671282 ! nuclear export GO:0051168 97 55 1,000 0,03585529 0,09660452 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03585529 0,09649646 ! tRNA transcription GO:0009304 14 7 0,000 0,03727962 0,1002176 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03727962 0,10010575 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03727962 0,09999415 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03727962 0,0998828 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03727962 0,0997717 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03727962 0,09966084 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03727962 0,09955023 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03727962 0,09943986 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03727962 0,09932974 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03727962 0,09921986 ! prostate gland development GO:0030850 13 7 0,000 0,03727962 0,09911023 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03727962 0,09900083 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03727962 0,09889168 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03727962 0,09878277 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03727962 0,0986741 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03727962 0,09856567 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03727962 0,09845747 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03727962 0,09834951 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03727962 0,09824179 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03727962 0,09813431 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03727962 0,09802706 ! glycolipid transport GO:0046836 10 7 0,000 0,03727962 0,09792004 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03727962 0,09781326 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03727962 0,09770671 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03727962 0,09760039 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03727962 0,0974943 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03727962 0,09738844 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03727962 0,09728282 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03727962 0,09717742 ! pericardium development GO:0060039 14 7 0,000 0,03727962 0,09707225 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03727962 0,0969673 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03727962 0,09686259 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03727962 0,0967581 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03727962 0,09665383 ! lipoprotein transport GO:0042953 14 7 0,000 0,03727962 0,09654979 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03727962 0,09644597 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03727962 0,09634238 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03727962 0,09623901 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03727962 0,09613586 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03727962 0,09603293 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03727962 0,09593022 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03727962 0,09582773 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03727962 0,09572546 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03727962 0,09562341 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03727962 0,09552157 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03727962 0,09541995 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03727962 0,09531855 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03727962 0,09521736 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03727962 0,09511639 ! spinal cord patterning GO:0021511 13 7 0,000 0,03727962 0,09501563 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03727962 0,09491509 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03727962 0,09481475 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03727962 0,09471463 ! adrenal gland development GO:0030325 17 7 0,000 0,03727962 0,09461472 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03727962 0,09451502 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03727962 0,09441553 ! ovulation GO:0030728 9 7 0,000 0,03727962 0,09431625 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03727962 0,09421718 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03727962 0,09411832 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,03727962 0,09401966 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03727962 0,09392121 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03727962 0,09382297 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03727962 0,09372493 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03727962 0,09362709 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03727962 0,09352946 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03727962 0,09343204 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03727962 0,09333481 ! galactose metabolic process GO:0006012 13 7 0,000 0,03727962 0,09323779 ! vesicle fusion GO:0006906 17 7 0,000 0,03727962 0,09314097 ! response to dietary excess GO:0002021 8 7 0,000 0,03727962 0,09304435 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03727962 0,09294793 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03727962 0,09285171 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03727962 0,09275569 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03727962 0,09265987 ! purine salvage GO:0043101 10 7 0,000 0,03727962 0,09256425 ! nucleoside transport GO:0015858 8 7 0,000 0,03727962 0,09246882 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03727962 0,09237359 ! parturition GO:0007567 14 7 0,000 0,03727962 0,09227856 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03727962 0,09218372 ! rRNA modification GO:0000154 14 7 0,000 0,03727962 0,09208907 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03727962 0,09199462 ! spindle checkpoint GO:0031577 15 7 0,000 0,03727962 0,09190036 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03727962 0,0918063 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03727962 0,09171243 ! macrophage differentiation GO:0030225 11 7 0,000 0,03727962 0,09161875 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03727962 0,09152526 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03727962 0,09143196 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03727962 0,09133886 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03727962 0,09124594 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03727962 0,09115321 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03727962 0,09106067 ! fibrinolysis GO:0042730 10 7 0,000 0,03727962 0,09096831 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03727962 0,09087615 ! eating behavior GO:0042755 7 7 0,000 0,03727962 0,09078417 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03727962 0,09069237 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03727962 0,09060076 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03727962 0,09050934 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03727962 0,0904181 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03727962 0,09032705 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03727962 0,09023617 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03727962 0,09014548 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03727962 0,09005498 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03727962 0,08996465 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03727962 0,0898745 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03727962 0,08978454 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03727962 0,08969476 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03727962 0,08960515 ! regulation of meiosis GO:0040020 12 7 0,000 0,03727962 0,08951572 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03727962 0,08942648 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03727962 0,08933741 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03727962 0,08924851 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03727962 0,0891598 ! transcription termination GO:0006353 13 7 0,000 0,03727962 0,08907126 ! response to tumor cell GO:0002347 13 7 0,000 0,03727962 0,08898289 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03727962 0,0888947 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03727962 0,08880669 ! anaphase GO:0051322 17 7 0,000 0,03727962 0,08871885 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03727962 0,08863118 ! axonal fasciculation GO:0007413 18 7 0,000 0,03727962 0,08854369 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03727962 0,08845637 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03727962 0,08836922 ! diuresis GO:0030146 12 7 0,000 0,03727962 0,08828224 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03727962 0,08819543 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03727962 0,0881088 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03727962 0,08802233 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03727962 0,08793604 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03727962 0,08784991 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03727962 0,08776395 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03727962 0,08767816 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03727962 0,08759254 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03727962 0,08750708 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03727962 0,08742179 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03727962 0,08733667 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,03727962 0,08725171 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03727962 0,08716692 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03727962 0,08708229 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03727962 0,08699782 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03727962 0,08691352 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03727962 0,08682939 ! adult feeding behavior GO:0008343 9 7 0,000 0,03727962 0,08674541 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03727962 0,0866616 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03727962 0,08657795 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03727962 0,08649446 ! muscle adaptation GO:0043500 14 7 0,000 0,03727962 0,08641113 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03727962 0,08632797 ! retina homeostasis GO:0001895 12 7 0,000 0,03727962 0,08624496 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03727962 0,08616211 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03727962 0,08607942 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03727962 0,08599689 ! protein prenylation GO:0018342 18 7 0,000 0,03727962 0,08591452 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03727962 0,0858323 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03727962 0,08575024 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03727962 0,08566834 ! regulation of heart contraction GO:0008016 110 60 1,000 0,04199827 0,0964197 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,04199827 0,09632779 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,04199827 0,09623604 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04249129 0,09727311 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04249129 0,09718064 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04249129 0,09708835 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04249129 0,09699624 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04249129 0,0969043 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04249129 0,09681254 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04249129 0,09672094 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04249129 0,09662952 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04249129 0,09653828 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04249129 0,0964472 ! meiotic prophase I GO:0007128 13 8 0,000 0,04249129 0,0963563 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04249129 0,09626557 ! oligopeptide transport GO:0006857 15 8 0,000 0,04249129 0,09617501 ! UTP metabolic process GO:0046051 8 8 0,000 0,04249129 0,09608462 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04249129 0,0959944 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04249129 0,09590435 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04249129 0,09581447 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04249129 0,09572475 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04249129 0,09563521 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04249129 0,09554583 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04249129 0,09545662 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04249129 0,09536757 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04249129 0,09527869 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04249129 0,09518998 ! reflex GO:0060004 16 8 0,000 0,04249129 0,09510143 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04249129 0,09501305 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04249129 0,09492483 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04249129 0,09483677 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04249129 0,09474888 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04249129 0,09466115 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04249129 0,09457358 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04249129 0,09448617 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04249129 0,09439893 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04249129 0,09431184 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04249129 0,09422492 ! histidine metabolic process GO:0006547 16 8 0,000 0,04249129 0,09413816 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04249129 0,09405155 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04249129 0,09396511 ! glycine catabolic process GO:0006546 13 8 0,000 0,04249129 0,09387882 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04249129 0,09379269 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04249129 0,09370673 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04249129 0,09362091 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04249129 0,09353526 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04249129 0,09344976 ! macrophage activation GO:0042116 12 8 0,000 0,04249129 0,09336442 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04249129 0,09327923 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04249129 0,0931942 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04249129 0,09310932 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04249129 0,0930246 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04249129 0,09294003 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04249129 0,09285562 ! osteoblast development GO:0002076 16 8 0,000 0,04249129 0,09277136 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04249129 0,09268725 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04249129 0,09260329 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04249129 0,09251949 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04249129 0,09243584 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04249129 0,09235234 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04249129 0,09226899 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04249129 0,09218579 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04249129 0,09210274 ! intermediate filament organization GO:0045109 12 8 0,000 0,04249129 0,09201984 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04249129 0,09193708 ! cellular extravasation GO:0045123 12 8 0,000 0,04249129 0,09185448 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04249129 0,09177203 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04249129 0,09168972 ! response to antibiotic GO:0046677 11 8 0,000 0,04249129 0,09160756 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04249129 0,09152555 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04249129 0,09144368 ! DNA topological change GO:0006265 12 8 0,000 0,04249129 0,09136196 ! response to tropane GO:0014073 15 8 0,000 0,04249129 0,09128039 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04249129 0,09119896 ! melanosome transport GO:0032402 13 8 0,000 0,04249129 0,09111768 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 0,000 0,04249129 0,09103654 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04249129 0,09095555 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04249129 0,0908747 ! mast cell activation GO:0045576 14 8 0,000 0,04249129 0,09079399 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04249129 0,09071343 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04249129 0,09063301 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04249129 0,09055273 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04249129 0,0904726 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04249129 0,09039261 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04249129 0,09031275 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04249129 0,09023304 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04249129 0,09015347 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04249129 0,09007404 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04249129 0,08999475 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04249129 0,0899156 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04249129 0,08983659 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04249129 0,08975771 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04249129 0,08967898 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04249129 0,08960038 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04249129 0,08952192 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04249129 0,0894436 ! hormone catabolic process GO:0042447 17 8 0,000 0,04249129 0,08936542 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04249129 0,08928737 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04249129 0,08920946 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04249129 0,08913168 ! ATP catabolic process GO:0006200 11 8 0,000 0,04249129 0,08905404 ! blastocyst growth GO:0001832 19 8 0,000 0,04249129 0,08897653 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04249129 0,08889916 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04249129 0,08882193 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04249129 0,08874482 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04249129 0,08866786 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04249129 0,08859102 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04249129 0,08851432 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04249129 0,08843775 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04249129 0,08836131 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04249129 0,08828501 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04249129 0,08820883 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04249129 0,08813279 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04249129 0,08805688 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04249129 0,0879811 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04249129 0,08790545 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04249129 0,08782993 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,04327107 0,08936497 ! gonad development GO:0008406 98 62 1,000 0,04455814 0,09194416 ! regulation of mitosis GO:0007088 105 63 1,000 0,04585931 0,09454798 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,04585931 0,09446703 ! detection of external stimulus GO:0009581 91 63 1,000 0,04585931 0,09438622 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,04585931 0,09430555 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,04717438 0,09692703 ! cell redox homeostasis GO:0045454 102 64 1,000 0,04717438 0,09684432 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,04717438 0,09676176 GO:0048609|reproductive process in a multicellular organism, ! regulation of developmental growth GO:0048638 15 9 0,000 0,04767492 0,09770515 ! axon extension GO:0048675 15 9 0,000 0,04767492 0,097622 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04767492 0,09753899 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04767492 0,09745612 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04767492 0,09737339 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04767492 0,0972908 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04767492 0,09720835 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04767492 0,09712604 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04767492 0,09704387 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04767492 0,09696184 ! phosphate transport GO:0006817 19 9 0,000 0,04767492 0,09687994 ! reproductive behavior GO:0019098 19 9 0,000 0,04767492 0,09679819 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04767492 0,09671657 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04767492 0,09663509 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04767492 0,09655375 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04767492 0,09647254 ! GTP metabolic process GO:0046039 9 9 0,000 0,04767492 0,09639147 ! RNA methylation GO:0001510 15 9 0,000 0,04767492 0,09631054 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04767492 0,09622974 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04767492 0,09614908 ! artery development GO:0060840 24 9 0,000 0,04767492 0,09606855 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04767492 0,09598816 ! regulation of glycolysis GO:0006110 21 9 0,000 0,04767492 0,0959079 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04767492 0,09582778 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04767492 0,09574779 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04767492 0,09566793 ! chemosensory behavior GO:0007635 20 9 0,000 0,04767492 0,09558821 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04767492 0,09550862 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04767492 0,09542916 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04767492 0,09534983 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04767492 0,09527064 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04767492 0,09519158 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04767492 0,09511265 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04767492 0,09503385 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04767492 0,09495517 ! protein targeting to ER GO:0045047 22 9 0,000 0,04767492 0,09487663 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04767492 0,09479822 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04767492 0,09471994 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04767492 0,09464179 ! endosome organization GO:0007032 17 9 0,000 0,04767492 0,09456377 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04767492 0,09448587 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04767492 0,09440811 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04767492 0,09433047 ! mannose metabolic process GO:0006013 13 9 0,000 0,04767492 0,09425296 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04767492 0,09417558 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04767492 0,09409832 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04767492 0,09402119 ! receptor clustering GO:0043113 18 9 0,000 0,04767492 0,09394419 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04767492 0,09386731 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04767492 0,09379056 ! ruffle organization GO:0031529 15 9 0,000 0,04767492 0,09371393 ! retinol metabolic process GO:0042572 18 9 0,000 0,04767492 0,09363743 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04767492 0,09356105 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04767492 0,0934848 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04767492 0,09340867 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04767492 0,09333267 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04767492 0,09325679 ! protein heterooligomerization GO:0051291 16 9 0,000 0,04767492 0,09318103 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04767492 0,0931054 ! segment specification GO:0007379 13 9 0,000 0,04767492 0,09302989 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04767492 0,0929545 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04767492 0,09287923 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04767492 0,09280409 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04767492 0,09272906 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04767492 0,09265416 ! erythrocyte development GO:0048821 15 9 0,000 0,04767492 0,09257938 ! gas homeostasis GO:0033483 16 9 0,000 0,04767492 0,09250472 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04767492 0,09243018 ! renal water homeostasis GO:0003091 14 9 0,000 0,04767492 0,09235576 ! postreplication repair GO:0006301 22 9 0,000 0,04767492 0,09228146 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04767492 0,09220728 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04767492 0,09213321 ! icosanoid secretion GO:0032309 15 9 0,000 0,04767492 0,09205927 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04767492 0,09198545 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04767492 0,09191174 ! regulation of cell division GO:0051302 15 9 0,000 0,04767492 0,09183815 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04767492 0,09176468 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04767492 0,09169133 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04767492 0,09161809 ! sterol catabolic process GO:0016127 11 9 0,000 0,04767492 0,09154497 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04767492 0,09147197 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04767492 0,09139908 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04767492 0,09132631 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04767492 0,09125366 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04767492 0,09118112 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04767492 0,0911087 GO:0050879|multicellular organismal movement, ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04767492 0,09103639 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04767492 0,0909642 ! purine base metabolic process GO:0006144 21 9 0,000 0,04767492 0,09089212 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04767492 0,09082015 ! pigment granule transport GO:0051904 17 9 0,000 0,04767492 0,0907483 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04767492 0,09067656 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04767492 0,09060494 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04767492 0,09053343 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04767492 0,09046203 ! mitochondrion localization GO:0051646 15 9 0,000 0,04767492 0,09039074 ! germ cell development GO:0007281 118 65 1,000 0,04850316 0,09188867 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,04850316 0,09181637 ! actin filament organization GO:0007015 148 66 1,000 0,04984548 0,0942832 ! extracellular matrix organization GO:0030198 133 66 1,000 0,04984548 0,09420914 ! secondary metabolic process GO:0019748 116 66 1,000 0,04984548 0,09413519 ! cell projection assembly GO:0030031 120 66 1,000 0,04984548 0,09406136 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,05120115 0,09654386 ! activation of MAPK activity GO:0000187 115 67 1,000 0,05120115 0,09646826 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,05120115 0,09639278 ! adaptive immune response GO:0002250 119 67 1,000 0,05120115 0,09631741 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,05256999 0,09881514 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,05256999 0,09873801 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05283066 0,0991502 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05283066 0,09907292 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05283066 0,09899576 ! synapsis GO:0007129 13 10 0,000 0,05283066 0,09891872 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05283066 0,0988418 ! N-glycan processing GO:0006491 20 10 0,000 0,05283066 0,098765 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05283066 0,09868832 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05283066 0,09861176 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05283066 0,09853532 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05283066 0,09845899 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05283066 0,09838279 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05283066 0,0983067 ! androgen metabolic process GO:0008209 17 10 0,000 0,05283066 0,09823073 ! phospholipid efflux GO:0033700 16 10 0,000 0,05283066 0,09815487 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05283066 0,09807914 ! pathogenesis GO:0009405 13 10 0,000 0,05283066 0,09800352 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05283066 0,09792801 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05283066 0,09785262 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05283066 0,09777735 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05283066 0,0977022 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05283066 0,09762716 ! endoderm development GO:0007492 16 10 0,000 0,05283066 0,09755223 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05283066 0,09747742 ! arginine catabolic process GO:0006527 13 10 0,000 0,05283066 0,09740273 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05283066 0,09732815 ! proline metabolic process GO:0006560 13 10 0,000 0,05283066 0,09725368 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05283066 0,09717933 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05283066 0,09710509 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05283066 0,09703096 ! V(D)J recombination GO:0033151 28 10 0,000 0,05283066 0,09695695 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05283066 0,09688305 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05283066 0,09680926 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05283066 0,09673559 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05283066 0,09666202 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05283066 0,09658857 ! multicellular organism growth GO:0035264 18 10 0,000 0,05283066 0,09651523 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05283066 0,096442 ! epithelial cell development GO:0002064 20 10 0,000 0,05283066 0,09636888 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05283066 0,09629588 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05283066 0,09622298 ! macroautophagy GO:0016236 17 10 0,000 0,05283066 0,0961502 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05283066 0,09607752 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05283066 0,09600495 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05283066 0,0959325 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05283066 0,09586015 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05283066 0,09578791 ! brain morphogenesis GO:0048854 23 10 0,000 0,05283066 0,09571578 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05283066 0,09564376 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05283066 0,09557185 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05283066 0,09550004 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05283066 0,09542835 ! response to dsRNA GO:0043331 20 10 0,000 0,05283066 0,09535676 ! DNA ligation GO:0006266 19 10 0,000 0,05283066 0,09528528 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05283066 0,0952139 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05283066 0,09514263 ! melanosome localization GO:0032400 16 10 0,000 0,05283066 0,09507147 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05283066 0,09500042 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05283066 0,09492947 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05283066 0,09485863 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05283066 0,09478789 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05283066 0,09471726 ! mRNA cleavage GO:0006379 17 10 0,000 0,05283066 0,09464673 ! protein sumoylation GO:0016925 15 10 0,000 0,05283066 0,09457631 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05283066 0,09450599 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05283066 0,09443578 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05283066 0,09436567 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05283066 0,09429567 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05283066 0,09422577 ! prophase GO:0051324 15 10 0,000 0,05283066 0,09415597 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05283066 0,09408628 ! apical protein localization GO:0045176 15 10 0,000 0,05283066 0,09401669 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05283066 0,0939472 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05283066 0,09387781 ! midbrain development GO:0030901 13 10 0,000 0,05283066 0,09380853 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05283066 0,09373935 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05283066 0,09367027 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05283066 0,0936013 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05283066 0,09353242 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05283066 0,09346365 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05283066 0,09339497 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05283066 0,0933264 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05283066 0,09325793 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05283066 0,09318956 ! blastocyst formation GO:0001825 17 10 0,000 0,05283066 0,09312129 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05283066 0,09305312 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05283066 0,09298505 ! activation of innate immune response GO:0002218 12 10 0,000 0,05283066 0,09291708 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05283066 0,0928492 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05283066 0,09278143 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05283066 0,09271376 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05283066 0,09264618 ! localization within membrane GO:0051668 20 10 0,000 0,05283066 0,0925787 ! reproductive structure development GO:0048608 113 71 1,000 0,0567537 0,09938093 ! humoral immune response GO:0006959 109 71 1,000 0,0567537 0,09930865 ! B cell activation GO:0042113 160 71 1,000 0,0567537 0,09923648 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,0567537 0,09916441 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05795865 0,10119631 ! respiratory burst GO:0045730 17 11 0,000 0,05795865 0,10112293 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05795865 0,10104965 ! neuron fate specification GO:0048665 17 11 0,000 0,05795865 0,10097648 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05795865 0,10090342 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05795865 0,10083046 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05795865 0,1007576 ! thyroid gland development GO:0030878 26 11 0,000 0,05795865 0,10068485 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,05795865 0,10061221 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05795865 0,10053967 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05795865 0,10046723 ! response to pain GO:0048265 24 11 0,000 0,05795865 0,1003949 ! T cell proliferation GO:0042098 26 11 0,000 0,05795865 0,10032268 ! bone resorption GO:0045453 16 11 0,000 0,05795865 0,10025055 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05795865 0,10017853 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05795865 0,10010662 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05795865 0,10003481 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05795865 0,0999631 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05795865 0,09989149 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05795865 0,09981999 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05795865 0,09974858 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05795865 0,09967728 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05795865 0,09960609 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,05795865 0,09953499 ! lipid digestion GO:0044241 18 11 0,000 0,05795865 0,09946399 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,05795865 0,0993931 ! UV protection GO:0009650 19 11 0,000 0,05795865 0,09932231 ! adult heart development GO:0007512 14 11 0,000 0,05795865 0,09925162 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05795865 0,09918102 ! temperature homeostasis GO:0001659 17 11 0,000 0,05795865 0,09911053 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05795865 0,09904014 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05795865 0,09896985 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05795865 0,09889966 ! pigment granule localization GO:0051875 20 11 0,000 0,05795865 0,09882957 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05795865 0,09875957 ! vasoconstriction GO:0042310 18 11 0,000 0,05795865 0,09868968 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05795865 0,09861989 ! embryonic axis specification GO:0000578 18 11 0,000 0,05795865 0,09855019 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05795865 0,09848059 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05795865 0,09841109 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05795865 0,09834169 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05795865 0,09827239 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05795865 0,09820318 ! zymogen activation GO:0031638 15 11 0,000 0,05795865 0,09813407 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05795865 0,09806506 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05795865 0,09799615 ! nucleosome positioning GO:0016584 15 11 0,000 0,05795865 0,09792733 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05795865 0,09785861 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05795865 0,09778999 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05795865 0,09772146 ! acid secretion GO:0046717 18 11 0,000 0,05795865 0,09765303 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05795865 0,09758469 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05795865 0,09751645 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05795865 0,0974483 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05795865 0,09738025 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,05795865 0,0973123 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05795865 0,09724443 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05795865 0,09717667 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,05795865 0,097109 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,05795865 0,09704142 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05795865 0,09697394 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05795865 0,09690655 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05795865 0,09683925 ! defense response to fungus GO:0050832 13 11 0,000 0,05795865 0,09677205 ! lysogeny GO:0030069 21 11 0,000 0,05795865 0,09670494 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05795865 0,09663792 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,05795865 0,096571 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05795865 0,09650417 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05795865 0,09643743 ! regulation of embryonic development GO:0045995 27 11 0,000 0,05795865 0,09637078 ! nucleus localization GO:0051647 19 11 0,000 0,05795865 0,09630423 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05795865 0,09623776 ! learning or memory GO:0007611 147 73 1,000 0,05960541 0,09890388 ! eye development GO:0001654 143 74 1,000 0,06104952 0,10123028 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,06250556 0,10357326 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06305906 0,10441851 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06305906 0,10434669 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06305906 0,10427498 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06305906 0,10420336 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06305906 0,10413184 ! virus-host interaction GO:0019048 29 12 0,000 0,06305906 0,10406042 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06305906 0,1039891 ! mating GO:0007618 17 12 0,000 0,06305906 0,10391787 ! protein complex disassembly GO:0043241 27 12 0,000 0,06305906 0,10384674 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06305906 0,10377571 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06305906 0,10370478 ! hippocampus development GO:0021766 26 12 0,000 0,06305906 0,10363394 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06305906 0,1035632 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06305906 0,10349256 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06305906 0,10342201 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06305906 0,10335156 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06305906 0,1032812 ! drug transport GO:0015893 16 12 0,000 0,06305906 0,10321095 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06305906 0,10314078 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06305906 0,10307071 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06305906 0,10300074 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06305906 0,10293086 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06305906 0,10286108 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06305906 0,10279139 ! forebrain cell migration GO:0021885 21 12 0,000 0,06305906 0,10272179 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06305906 0,10265229 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06305906 0,10258289 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06305906 0,10251357 ! entry into host cell GO:0030260 32 12 0,000 0,06305906 0,10244436 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,06305906 0,10237523 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06305906 0,1023062 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06305906 0,10223726 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06305906 0,10216841 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06305906 0,10209966 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06305906 0,102031 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06305906 0,10196243 ! protein homotetramerization GO:0051289 21 12 0,000 0,06305906 0,10189395 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06305906 0,10182556 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06305906 0,10175727 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06305906 0,10168907 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06305906 0,10162096 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06305906 0,10155294 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06305906 0,10148501 ! fucose catabolic process GO:0019317 22 12 0,000 0,06305906 0,10141717 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06305906 0,10134943 ! histone methylation GO:0016571 26 12 0,000 0,06305906 0,10128177 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06305906 0,1012142 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06305906 0,10114673 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06305906 0,10107934 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06305906 0,10101204 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06305906 0,10094484 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06305906 0,10087772 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06305906 0,10081069 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06305906 0,10074375 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06305906 0,1006769 ! response to cold GO:0009409 17 12 0,000 0,06305906 0,10061014 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06305906 0,10054347 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06305906 0,10047688 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,06397337 0,10186627 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,06694362 0,10652537 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,06694362 0,10645496 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06813201 0,1082732 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06813201 0,10820173 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06813201 0,10813036 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06813201 0,10805908 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06813201 0,1079879 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06813201 0,1079168 ! lipid localization GO:0010876 28 13 0,000 0,06813201 0,10784581 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06813201 0,1077749 ! organelle fusion GO:0048284 32 13 0,000 0,06813201 0,10770409 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06813201 0,10763337 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,06813201 0,10756275 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06813201 0,10749221 ! endocrine pancreas development GO:0031018 22 13 0,000 0,06813201 0,10742177 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06813201 0,10735142 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06813201 0,10728117 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06813201 0,107211 ! methionine metabolic process GO:0006555 27 13 0,000 0,06813201 0,10714093 ! plasma membrane organization GO:0007009 24 13 0,000 0,06813201 0,10707095 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06813201 0,10700106 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,06813201 0,10693126 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06813201 0,10686155 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06813201 0,10679194 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,06813201 0,10672241 ! response to X-ray GO:0010165 25 13 0,000 0,06813201 0,10665298 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06813201 0,10658363 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06813201 0,10651438 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,06813201 0,10644521 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06813201 0,10637614 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06813201 0,10630715 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06813201 0,10623825 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06813201 0,10616945 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06813201 0,10610073 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06813201 0,1060321 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,06813201 0,10596356 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06813201 0,10589511 ! regulation of cellular pH GO:0030641 22 13 0,000 0,06813201 0,10582674 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06813201 0,10575847 ! ribosome assembly GO:0042255 17 13 0,000 0,06813201 0,10569028 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,06813201 0,10562218 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06813201 0,10555417 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06813201 0,10548624 ! chromatin silencing GO:0006342 26 13 0,000 0,06813201 0,10541841 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06813201 0,10535066 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06813201 0,105283 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06813201 0,10521542 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06813201 0,10514793 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06813201 0,10508053 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06813201 0,10501321 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06813201 0,10494598 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06813201 0,10487884 ! embryonic placenta development GO:0001892 23 13 0,000 0,06813201 0,10481178 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06813201 0,10474481 ! insulin secretion GO:0030073 23 13 0,000 0,06813201 0,10467792 ! actin filament polymerization GO:0030041 24 13 0,000 0,06813201 0,10461112 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06813201 0,1045444 ! acrosome reaction GO:0007340 18 13 0,000 0,06813201 0,10447777 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,06844573 0,104892 ! muscle cell differentiation GO:0042692 159 80 1,000 0,06995895 0,10714273 ! T cell activation GO:0042110 168 81 1,000 0,0714831 0,10940735 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,0714831 0,10933779 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,07301804 0,11161461 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,07301804 0,11154375 ! rRNA transcription GO:0009303 25 14 0,000 0,07317767 0,11171667 ! lactation GO:0007595 26 14 0,000 0,07317767 0,11164583 ! reproductive cellular process GO:0048610 20 14 0,000 0,07317767 0,11157508 ! tRNA modification GO:0006400 20 14 0,000 0,07317767 0,11150442 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07317767 0,11143385 ! regulation of S phase GO:0033261 23 14 0,000 0,07317767 0,11136336 ! water transport GO:0006833 21 14 0,000 0,07317767 0,11129297 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07317767 0,11122266 ! non-recombinational repair GO:0000726 25 14 0,000 0,07317767 0,11115245 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07317767 0,11108232 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07317767 0,11101228 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07317767 0,11094233 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07317767 0,11087247 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07317767 0,11080269 ! palate development GO:0060021 31 14 0,000 0,07317767 0,110733 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,07317767 0,1106634 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07317767 0,11059389 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07317767 0,11052447 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07317767 0,11045513 ! arginine metabolic process GO:0006525 17 14 0,000 0,07317767 0,11038588 ! regulation of heart rate GO:0002027 24 14 0,000 0,07317767 0,11031672 ! organic alcohol transport GO:0015850 29 14 0,000 0,07317767 0,11024764 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07317767 0,11017865 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07317767 0,11010974 ! embryo implantation GO:0007566 30 14 0,000 0,07317767 0,11004092 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07317767 0,10997219 ! L-amino acid transport GO:0015807 30 14 0,000 0,07317767 0,10990354 ! bone mineralization GO:0030282 17 14 0,000 0,07317767 0,10983498 ! stem cell development GO:0048864 43 14 0,000 0,07317767 0,10976651 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07317767 0,10969812 ! cerebellum development GO:0021549 21 14 0,000 0,07317767 0,10962981 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07317767 0,10956159 ! cofactor transport GO:0051181 26 14 0,000 0,07317767 0,10949346 ! NADP metabolic process GO:0006739 24 14 0,000 0,07317767 0,10942541 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07317767 0,10935744 ! intestinal absorption GO:0050892 25 14 0,000 0,07317767 0,10928956 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07317767 0,10922176 ! oxygen transport GO:0015671 21 14 0,000 0,07317767 0,10915405 ! male genitalia development GO:0030539 24 14 0,000 0,07317767 0,10908642 ! regulation of axon extension GO:0030516 37 14 0,000 0,07317767 0,10901887 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07317767 0,10895141 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,07611961 0,11326146 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07819618 0,11627936 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,07819618 0,11620753 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07819618 0,1161358 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07819618 0,11606416 ! copper ion transport GO:0006825 20 15 0,000 0,07819618 0,1159926 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07819618 0,11592113 ! sulfate transport GO:0008272 23 15 0,000 0,07819618 0,11584975 ! response to cAMP GO:0051591 22 15 0,000 0,07819618 0,11577846 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07819618 0,11570726 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07819618 0,11563614 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07819618 0,11556511 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07819618 0,11549417 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07819618 0,11542331 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07819618 0,11535254 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07819618 0,11528186 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07819618 0,11521127 ! pituitary gland development GO:0021983 29 15 0,000 0,07819618 0,11514076 ! vesicle coating GO:0006901 33 15 0,000 0,07819618 0,11507034 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,07819618 0,115 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07819618 0,11492975 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,07819618 0,11485958 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07819618 0,11478951 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,07819618 0,11471951 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07819618 0,1146496 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07819618 0,11457978 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07819618 0,11451004 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07819618 0,11444039 ! histone deacetylation GO:0016575 20 15 0,000 0,07819618 0,11437082 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07819618 0,11430134 ! tissue regeneration GO:0042246 26 15 0,000 0,07819618 0,11423194 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07819618 0,11416262 ! water homeostasis GO:0030104 27 15 0,000 0,07819618 0,11409339 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07819618 0,11402424 ! muscle maintenance GO:0046716 26 15 0,000 0,07819618 0,11395518 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07819618 0,1138862 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07819618 0,1138173 ! cell killing GO:0001906 29 15 0,000 0,07819618 0,11374849 ! detection of bacterium GO:0016045 18 15 0,000 0,07819618 0,11367976 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07819618 0,11361111 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07819618 0,11354255 ! peptide hormone processing GO:0016486 23 15 0,000 0,07819618 0,11347406 ! amine biosynthetic process GO:0009309 138 86 1,000 0,0792624 0,11495199 ! regulation of neurological system process GO:0031644 148 88 1,000 0,08244518 0,11949585 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08318767 0,12049942 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08318767 0,12042692 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08318767 0,1203545 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08318767 0,12028218 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08318767 0,12020993 ! bone remodeling GO:0046849 27 16 0,000 0,08318767 0,12013778 ! filopodium assembly GO:0046847 32 16 0,000 0,08318767 0,12006571 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08318767 0,11999373 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08318767 0,11992183 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08318767 0,11985002 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08318767 0,1197783 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08318767 0,11970666 ! startle response GO:0001964 28 16 0,000 0,08318767 0,11963511 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08318767 0,11956364 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08318767 0,11949226 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08318767 0,11942097 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08318767 0,11934976 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08318767 0,11927863 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08318767 0,11920759 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08318767 0,11913663 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08318767 0,11906576 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08318767 0,11899497 ! response to osmotic stress GO:0006970 25 16 0,000 0,08318767 0,11892427 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08318767 0,11885365 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08318767 0,11878311 ! fructose metabolic process GO:0006000 25 16 0,000 0,08318767 0,11871266 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08318767 0,11864229 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,08318767 0,118572 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08318767 0,1185018 ! axon cargo transport GO:0008088 43 16 0,000 0,08318767 0,11843168 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08318767 0,11836164 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08318767 0,11829169 ! DNA replication initiation GO:0006270 27 16 0,000 0,08318767 0,11822182 ! neuron recognition GO:0008038 35 16 0,000 0,08318767 0,11815203 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08318767 0,11808232 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08318767 0,1180127 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08318767 0,11794316 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08318767 0,1178737 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08318767 0,11780432 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08318767 0,11773502 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08318767 0,11766581 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08318767 0,11759667 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08318767 0,11752762 ! sex differentiation GO:0007548 145 90 1,000 0,08566673 0,12095901 ! sterol metabolic process GO:0016125 152 91 1,000 0,08729166 0,12318108 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0881523 0,12432265 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0881523 0,12424982 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,0881523 0,12417708 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0881523 0,12410442 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0881523 0,12403184 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0881523 0,12395935 ! signal complex assembly GO:0007172 41 17 0,000 0,0881523 0,12388694 ! endothelial cell migration GO:0043542 28 17 0,000 0,0881523 0,12381462 ! inositol metabolic process GO:0006020 28 17 0,000 0,0881523 0,12374238 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0881523 0,12367023 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0881523 0,12359816 ! glial cell development GO:0021782 27 17 0,000 0,0881523 0,12352618 ! limbic system development GO:0021761 36 17 0,000 0,0881523 0,12345428 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,0881523 0,12338246 ! adult walking behavior GO:0007628 33 17 0,000 0,0881523 0,12331072 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0881523 0,12323907 ! heart looping GO:0001947 30 17 0,000 0,0881523 0,12316751 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0881523 0,12309602 ! myoblast differentiation GO:0045445 45 17 0,000 0,0881523 0,12302462 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0881523 0,1229533 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,0881523 0,12288207 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0881523 0,12281091 ! glycine metabolic process GO:0006544 28 17 0,000 0,0881523 0,12273984 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,0881523 0,12266885 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0881523 0,12259795 ! NAD metabolic process GO:0019674 29 17 0,000 0,0881523 0,12252712 ! membrane budding GO:0006900 37 17 0,000 0,0881523 0,12245638 ! DNA integration GO:0015074 29 17 0,000 0,0881523 0,12238572 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,0881523 0,12231514 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0881523 0,12224464 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0881523 0,12217422 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0881523 0,12210388 ! genitalia development GO:0048806 30 17 0,000 0,0881523 0,12203363 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0881523 0,12196345 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0881523 0,12189336 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,0881523 0,12182335 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0881523 0,12175341 ! steroid catabolic process GO:0006706 31 17 0,000 0,0881523 0,12168356 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0881523 0,12161379 ! gas transport GO:0015669 25 17 0,000 0,0881523 0,12154409 ! organic cation transport GO:0015695 31 17 0,000 0,0881523 0,12147448 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0881523 0,12140495 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0881523 0,1213355 ! microspike assembly GO:0030035 36 17 0,000 0,0881523 0,12126612 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0881523 0,12119683 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,0881523 0,12112761 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,09056913 0,12437746 ! regulation of membrane potential GO:0042391 164 93 1,000 0,09056913 0,12430651 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,09222136 0,12650205 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09309022 0,12762112 ! neuron maturation GO:0042551 42 18 0,000 0,09309022 0,12754844 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09309022 0,12747585 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09309022 0,12740334 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,09309022 0,12733091 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09309022 0,12725856 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09309022 0,12718629 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09309022 0,12711411 ! memory GO:0007613 31 18 0,000 0,09309022 0,12704201 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09309022 0,12696999 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09309022 0,12689805 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09309022 0,1268262 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09309022 0,12675442 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09309022 0,12668273 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09309022 0,12661112 ! response to retinoic acid GO:0032526 26 18 0,000 0,09309022 0,12653958 ! response to fungus GO:0009620 21 18 0,000 0,09309022 0,12646813 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09309022 0,12639676 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09309022 0,12632547 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09309022 0,12625426 ! vitamin transport GO:0051180 27 18 0,000 0,09309022 0,12618313 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09309022 0,12611209 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09309022 0,12604112 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,09309022 0,12597023 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09309022 0,12589942 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09309022 0,12582869 ! leukocyte differentiation GO:0002521 202 96 1,000 0,09555212 0,12908388 ! positive regulation of immune response GO:0050778 156 96 1,000 0,09555212 0,12901144 ! detection of stimulus GO:0051606 151 96 1,000 0,09555212 0,12893909 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,09723036 0,13113018 ! protein secretion GO:0009306 39 19 0,000 0,09800155 0,13209621 ! positive regulation of translation GO:0045727 30 19 0,000 0,09800155 0,13202225 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09800155 0,13194837 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09800155 0,13187457 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09800155 0,13180086 ! skin development GO:0043588 36 19 0,000 0,09800155 0,13172723 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09800155 0,13165368 ! lipid phosphorylation GO:0046834 35 19 0,000 0,09800155 0,13158021 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09800155 0,13150683 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09800155 0,13143352 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09800155 0,1313603 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09800155 0,13128716 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09800155 0,1312141 ! cerebral cortex development GO:0021987 36 19 0,000 0,09800155 0,13114112 ! pigmentation during development GO:0048066 41 19 0,000 0,09800155 0,13106823 ! response to vitamin A GO:0033189 27 19 0,000 0,09800155 0,13099541 ! heme metabolic process GO:0042168 36 19 0,000 0,09800155 0,13092267 ! actin filament bundle formation GO:0051017 42 19 0,000 0,09800155 0,13085002 ! neuromuscular junction development GO:0007528 34 19 0,000 0,09800155 0,13077745 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09800155 0,13070495 ! plasma membrane fusion GO:0045026 28 19 0,000 0,09800155 0,13063254 ! peptide cross-linking GO:0018149 37 19 0,000 0,09800155 0,13056021 ! protein export from nucleus GO:0006611 36 19 0,000 0,09800155 0,13048796 ! heart process GO:0003015 30 19 0,000 0,09800155 0,13041578 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09800155 0,13034369 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,09800155 0,13027168 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09800155 0,13019974 ! cell-cell junction organization GO:0045216 35 19 0,000 0,09800155 0,13012789 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09800155 0,13005612 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,09800155 0,12998442 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09800155 0,1299128 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09800155 0,12984127 ! cilium assembly GO:0042384 37 19 0,000 0,09800155 0,12976981 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09800155 0,12969843 ! response to virus GO:0009615 160 98 1,000 0,09891698 0,13083797 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10288645 0,13601363 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10288645 0,13593894 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10288645 0,13586433 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10288645 0,1357898 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10288645 0,13571536 ! response to vitamin GO:0033273 31 20 0,000 0,10288645 0,13564099 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10288645 0,13556671 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,10288645 0,13549251 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10288645 0,13541839 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10288645 0,13534435 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10288645 0,13527039 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10288645 0,13519651 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10288645 0,13512271 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10288645 0,135049 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,10288645 0,13497536 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,10288645 0,1349018 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10288645 0,13482833 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10288645 0,13475493 ! body fluid secretion GO:0007589 31 20 0,000 0,10288645 0,13468162 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10288645 0,13460838 ! peptide secretion GO:0002790 35 20 0,000 0,10288645 0,13453522 ! stem cell differentiation GO:0048863 53 20 0,000 0,10288645 0,13446215 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10288645 0,13438915 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10288645 0,13431623 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10288645 0,13424339 ! sensory perception of pain GO:0019233 30 20 0,000 0,10288645 0,13417063 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10288645 0,13409795 ! diencephalon development GO:0021536 34 20 0,000 0,10288645 0,13402534 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10288645 0,13395282 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10288645 0,13388037 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10288645 0,133808 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10288645 0,13373572 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10288645 0,1336635 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10288645 0,13359137 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10288645 0,13351931 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,10288645 0,13344734 ! regulation of glucose import GO:0046324 29 20 0,000 0,10288645 0,13337544 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10288645 0,13330361 ! actin filament-based movement GO:0030048 43 20 0,000 0,10288645 0,13323187 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10288645 0,1331602 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10288645 0,13308861 ! negative regulation of translation GO:0017148 29 20 0,000 0,10288645 0,13301709 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,10288645 0,13294565 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10288645 0,13287429 ! regulation of cell killing GO:0031341 42 21 0,000 0,10774506 0,13907437 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,10774506 0,1389998 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,10774506 0,1389253 ! hormone secretion GO:0046879 38 21 0,000 0,10774506 0,13885089 ! glycerol metabolic process GO:0006071 34 21 0,000 0,10774506 0,13877656 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,10774506 0,13870231 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,10774506 0,13862814 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,10774506 0,13855405 ! axis specification GO:0009798 38 21 0,000 0,10774506 0,13848003 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,10774506 0,1384061 ! smooth muscle contraction GO:0006939 46 21 0,000 0,10774506 0,13833224 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,10774506 0,13825846 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,10774506 0,13818476 ! cytolysis GO:0019835 24 21 0,000 0,10774506 0,13811114 ! vasodilation GO:0042311 39 21 0,000 0,10774506 0,1380376 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,10774506 0,13796414 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,10774506 0,13789075 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,10774506 0,13781745 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,10774506 0,13774422 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,10774506 0,13767107 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,10774506 0,13759799 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,10774506 0,137525 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,10774506 0,13745208 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,10774506 0,13737924 ! collagen catabolic process GO:0030574 28 21 0,000 0,10774506 0,13730647 ! sperm-egg recognition GO:0035036 21 21 0,000 0,10774506 0,13723378 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,11257752 0,14331297 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11257752 0,14323718 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11257752 0,14316147 ! microtubule-based transport GO:0010970 54 22 0,000 0,11257752 0,14308584 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11257752 0,1430103 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11257752 0,14293483 ! keratinization GO:0031424 28 22 0,000 0,11257752 0,14285944 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11257752 0,14278414 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11257752 0,14270891 ! sensory perception of taste GO:0050909 28 22 0,000 0,11257752 0,14263376 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,11257752 0,14255869 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,11257752 0,1424837 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11257752 0,14240878 ! vacuolar transport GO:0007034 36 22 0,000 0,11257752 0,14233395 ! lysosome organization GO:0007040 41 22 0,000 0,11257752 0,14225919 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11257752 0,14218452 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11257752 0,14210992 ! fucose metabolic process GO:0006004 39 22 0,000 0,11257752 0,1420354 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11257752 0,14196096 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11257752 0,14188659 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11257752 0,14181231 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11257752 0,1417381 ! sarcomere organization GO:0045214 30 22 0,000 0,11257752 0,14166397 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11257752 0,14158991 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11257752 0,14151594 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11257752 0,14144204 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,11257752 0,14136822 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11257752 0,14129447 ! protein stabilization GO:0050821 39 22 0,000 0,11257752 0,14122081 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,11738396 0,14717343 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,11738396 0,14709677 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11738396 0,1470202 ! gluconeogenesis GO:0006094 33 23 0,000 0,11738396 0,14694371 ! viral genome replication GO:0019079 41 23 0,000 0,11738396 0,14686729 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11738396 0,14679096 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11738396 0,1467147 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11738396 0,14663853 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11738396 0,14656243 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11738396 0,14648641 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11738396 0,14641047 ! visual behavior GO:0007632 42 23 0,000 0,11738396 0,14633461 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11738396 0,14625883 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,11738396 0,14618313 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,11738396 0,1461075 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11738396 0,14603196 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,11738396 0,14595649 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,11738396 0,1458811 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11738396 0,14580578 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,11738396 0,14573055 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11738396 0,14565539 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11738396 0,14558031 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11738396 0,14550531 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11738396 0,14543038 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11738396 0,14535553 ! fatty acid transport GO:0015908 44 23 0,000 0,11738396 0,14528076 ! platelet activation GO:0030168 37 23 0,000 0,11738396 0,14520607 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11738396 0,14513145 ! hormone transport GO:0009914 40 23 0,000 0,11738396 0,14505691 ! cell-cell recognition GO:0009988 25 23 0,000 0,11738396 0,14498245 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11738396 0,14490806 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11738396 0,14483375 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11738396 0,14475951 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11738396 0,14468535 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11738396 0,14461127 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,12216453 0,15042367 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,12216453 0,15034673 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,12216453 0,15026986 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,12216453 0,15019308 ! vesicle docking GO:0048278 47 24 0,000 0,12216453 0,15011637 ! spinal cord development GO:0021510 47 24 0,000 0,12216453 0,15003974 ! vacuole organization GO:0007033 43 24 0,000 0,12216453 0,14996319 ! digestive system process GO:0022600 39 24 0,000 0,12216453 0,14988672 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,12216453 0,14981032 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,12216453 0,149734 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,12216453 0,14965776 ! membrane depolarization GO:0051899 39 24 0,000 0,12216453 0,1495816 ! pallium development GO:0021543 49 24 0,000 0,12216453 0,14950552 ! pentose metabolic process GO:0019321 35 24 0,000 0,12216453 0,14942951 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,12216453 0,14935358 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,12216453 0,14927773 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,12216453 0,14920195 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,12216453 0,14912626 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,12216453 0,14905063 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,12216453 0,14897509 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,12216453 0,14889962 ! regulation of amine transport GO:0051952 40 24 0,000 0,12216453 0,14882423 ! protein tetramerization GO:0051262 52 24 0,000 0,12216453 0,14874891 ! myelination GO:0042552 45 25 0,000 0,12691936 0,15446028 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12691936 0,15438219 ! phototransduction GO:0007602 33 25 0,000 0,12691936 0,15430418 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12691936 0,15422625 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,12691936 0,1541484 ! sperm motility GO:0030317 31 25 0,000 0,12691936 0,15407062 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12691936 0,15399293 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,12691936 0,15391531 ! receptor metabolic process GO:0043112 46 25 0,000 0,12691936 0,15383777 ! chromosome condensation GO:0030261 45 25 0,000 0,12691936 0,15376031 ! response to starvation GO:0042594 42 25 0,000 0,12691936 0,15368293 ! neural crest cell development GO:0014032 54 25 0,000 0,12691936 0,15360562 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12691936 0,15352839 ! negative regulation of cell development GO:0010721 73 25 0,000 0,12691936 0,15345125 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12691936 0,15337417 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12691936 0,15329718 ! interaction with host GO:0051701 62 25 0,000 0,12691936 0,15322026 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12691936 0,15314342 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,12691936 0,15306666 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12691936 0,15298997 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12691936 0,15291336 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,12691936 0,15283683 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,12691936 0,15276037 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12691936 0,15268399 ! telomere organization GO:0032200 43 25 0,000 0,12691936 0,15260768 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12691936 0,15253146 GO:0060606|tube closure, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13164859 0,15813605 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13164859 0,15805714 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13164859 0,15797831 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13164859 0,15789956 ! initiation of viral infection GO:0019059 57 26 0,000 0,13164859 0,15782089 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13164859 0,15774229 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,13164859 0,15766377 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13164859 0,15758533 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13164859 0,15750697 ! tube lumen formation GO:0035148 50 26 0,000 0,13164859 0,15742869 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13164859 0,15735048 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13164859 0,15727235 GO:0051297|centrosome organization, ! insulin receptor signaling pathway GO:0008286 64 26 0,000 0,13164859 0,1571943 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13164859 0,15711633 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13164859 0,15703843 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13164859 0,15696061 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,13164859 0,15688287 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13164859 0,15680521 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13164859 0,15672762 ! blastocyst development GO:0001824 49 26 0,000 0,13164859 0,15665011 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13164859 0,15657267 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,13164859 0,15649531 ! neuron fate commitment GO:0048663 48 27 0,000 0,13635237 0,16200681 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13635237 0,16192685 ! iron ion transport GO:0006826 59 27 0,000 0,13635237 0,16184697 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 0,000 0,13635237 0,16176716 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13635237 0,16168743 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13635237 0,16160778 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13635237 0,16152821 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13635237 0,16144872 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13635237 0,16136931 ! autophagy GO:0006914 41 27 0,000 0,13635237 0,16128997 ! primary neural tube formation GO:0014020 51 27 0,000 0,13635237 0,16121071 ! base-excision repair GO:0006284 41 27 0,000 0,13635237 0,16113153 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13635237 0,16105243 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13635237 0,1609734 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13635237 0,16089446 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,13635237 0,16081559 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13635237 0,1607368 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14103082 0,16617049 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14103082 0,16608916 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14103082 0,1660079 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,14103082 0,16592672 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14103082 0,16584563 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14103082 0,16576461 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14103082 0,16568367 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14103082 0,16560281 ! lipid oxidation GO:0034440 43 28 0,000 0,14103082 0,16552202 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14103082 0,16544132 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,14103082 0,1653607 ! translational initiation GO:0006413 65 29 0,000 0,14568408 0,17073351 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,14568408 0,17065039 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14568408 0,17056735 ! regulation of pH GO:0006885 43 29 0,000 0,14568408 0,17048439 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14568408 0,17040151 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,14568408 0,17031871 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14568408 0,17023599 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14568408 0,17015335 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,14568408 0,17007079 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,14568408 0,16998831 ! cell fate determination GO:0001709 60 29 0,000 0,14568408 0,16990591 ! detection of light stimulus GO:0009583 38 29 0,000 0,14568408 0,16982359 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,14568408 0,16974135 ! regulation of coagulation GO:0050818 46 29 0,000 0,14568408 0,16965919 ! zinc ion transport GO:0006829 45 30 0,000 0,15031229 0,17496437 ! membrane docking GO:0022406 61 30 0,000 0,15031229 0,17487977 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,15031229 0,17479525 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15031229 0,1747108 ! acute-phase response GO:0006953 49 30 0,000 0,15031229 0,17462644 ! myofibril assembly GO:0030239 47 30 0,000 0,15031229 0,17454216 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15031229 0,17445797 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15031229 0,17437385 ! phospholipid transport GO:0015914 51 30 0,000 0,15031229 0,17428981 ! ensheathment of neurons GO:0007272 57 30 0,000 0,15031229 0,17420586 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15031229 0,17412198 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15031229 0,17403819 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15031229 0,17395448 ! eye morphogenesis GO:0048592 60 30 0,000 0,15031229 0,17387085 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,15491557 0,1791095 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,15491557 0,17902347 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,15491557 0,17893753 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,15491557 0,17885167 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,15491557 0,17876589 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,15491557 0,17868019 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,15491557 0,17859457 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,15491557 0,17850904 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,15491557 0,17842359 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,15491557 0,17833822 ! peptide transport GO:0015833 55 31 0,000 0,15491557 0,17825293 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,15491557 0,17816772 ! mesoderm formation GO:0001707 69 31 0,000 0,15491557 0,17808259 ! natural killer cell activation GO:0030101 45 31 0,000 0,15491557 0,17799755 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,15491557 0,17791259 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,15491557 0,17782771 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,15491557 0,1777429 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,15491557 0,17765818 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15949407 0,1828217 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15949407 0,18273464 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15949407 0,18264766 ! cholesterol transport GO:0030301 56 32 0,000 0,15949407 0,18256077 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15949407 0,18247396 ! spliceosome assembly GO:0000245 67 32 0,000 0,15949407 0,18238724 ! spindle organization GO:0007051 46 32 0,000 0,15949407 0,18230059 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15949407 0,18221403 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15949407 0,18212755 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15949407 0,18204115 ! muscle cell development GO:0055001 49 32 0,000 0,15949407 0,18195483 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15949407 0,1818686 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15949407 0,18178245 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15949407 0,18169637 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,15949407 0,18161038 ! peripheral nervous system development GO:0007422 64 32 0,000 0,15949407 0,18152448 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15949407 0,18143865 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,15949407 0,1813529 ! gene silencing GO:0016458 65 32 0,000 0,15949407 0,18126724 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,16404792 0,18635472 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,16404792 0,18626678 ! protein targeting to membrane GO:0006612 68 33 0,000 0,16404792 0,18617891 ! ceramide metabolic process GO:0006672 64 33 0,000 0,16404792 0,18609113 ! formation of primary germ layer GO:0001704 72 33 0,000 0,16404792 0,18600344 ! sterol transport GO:0015918 57 33 0,000 0,16404792 0,18591583 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,16404792 0,18582829 ! adult locomotory behavior GO:0008344 59 33 0,000 0,16404792 0,18574085 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,16404792 0,18565348 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,16404792 0,1855662 ! glial cell differentiation GO:0010001 63 34 0,000 0,16857724 0,19060002 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16857724 0,1905105 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,16857724 0,19042106 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16857724 0,1903317 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16857724 0,19024243 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16857724 0,19015324 ! mismatch repair GO:0006298 46 34 0,000 0,16857724 0,19006413 ! spermatid development GO:0007286 63 34 0,000 0,16857724 0,18997511 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16857724 0,18988617 ! placenta development GO:0001890 53 34 0,000 0,16857724 0,18979731 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,16857724 0,18970854 ! negative regulation of secretion GO:0051048 63 35 0,000 0,17308218 0,19468711 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,17308218 0,19459613 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,17308218 0,19450524 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,17308218 0,19441444 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,17308218 0,19432371 ! cytokine production GO:0001816 59 35 0,000 0,17308218 0,19423308 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,17308218 0,19414253 ! neural tube formation GO:0001841 67 35 0,000 0,17308218 0,19405206 ! vesicle localization GO:0051648 64 35 0,000 0,17308218 0,19396168 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,17756285 0,19889023 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,17756285 0,19879768 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17756285 0,19870522 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17756285 0,19861284 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,17756285 0,19852055 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,17756285 0,19842834 ! regulation of proteolysis GO:0030162 72 36 0,000 0,17756285 0,19833622 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,17756285 0,19824419 ! aerobic respiration GO:0009060 55 36 0,000 0,17756285 0,19815224 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,17756285 0,19806037 ! RNA export from nucleus GO:0006405 56 37 0,000 0,18201939 0,20293729 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,18201939 0,20284329 ! meiosis I GO:0007127 65 37 0,000 0,18201939 0,20274938 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,18201939 0,20265556 ! sister chromatid segregation GO:0000819 58 37 0,000 0,18201939 0,20256182 ! actomyosin structure organization GO:0031032 62 37 0,000 0,18201939 0,20246817 ! organic anion transport GO:0015711 68 37 0,000 0,18201939 0,20237461 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,18201939 0,20228114 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,18201939 0,20218775 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,18201939 0,20209444 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,18201939 0,20200123 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,18201939 0,2019081 ! cellular response to insulin stimulus GO:0032869 82 37 0,000 0,18201939 0,20181505 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,18645193 0,20663443 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,18645193 0,2065393 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18645193 0,20644425 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18645193 0,20634929 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18645193 0,20625442 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,18645193 0,20615963 ! carbohydrate homeostasis GO:0033500 53 38 0,000 0,18645193 0,20606493 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 0,000 0,18645193 0,20597032 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,18645193 0,20587579 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18645193 0,20578136 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18645193 0,205687 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1908606 0,21045399 ! mammary gland development GO:0030879 86 39 0,000 0,1908606 0,21035759 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1908606 0,21026127 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1908606 0,21016504 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1908606 0,2100689 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,1908606 0,20997284 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1908606 0,20987688 ! RNA modification GO:0009451 57 39 0,000 0,1908606 0,209781 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1908606 0,20968521 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,19524553 0,21440472 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,19524553 0,21430691 ! feeding behavior GO:0007631 59 40 0,000 0,19524553 0,21420918 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,19524553 0,21411155 ! maintenance of protein location GO:0045185 91 40 0,000 0,19524553 0,214014 ! cytokinesis GO:0000910 72 40 0,000 0,19524553 0,21391655 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19960683 0,21859537 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,19960683 0,21849592 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19960683 0,21839656 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,19960683 0,21829729 ! polyol metabolic process GO:0019751 66 41 0,000 0,19960683 0,21819811 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,20394465 0,2228387 ! regulation of tube size GO:0035150 71 42 0,000 0,20394465 0,22273755 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,20394465 0,22263649 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,20394465 0,22253552 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,20394465 0,22243464 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,20394465 0,22233385 ! neuron migration GO:0001764 79 42 0,000 0,20394465 0,22223316 ! regulation of protein secretion GO:0050708 71 42 0,000 0,20394465 0,22213256 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,20825909 0,22672913 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,20825909 0,22662658 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20825909 0,22652413 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,20825909 0,22642177 ! glucose transport GO:0015758 65 43 0,000 0,20825909 0,2263195 ! neural tube development GO:0021915 77 43 0,000 0,20825909 0,22621733 ! striated muscle contraction GO:0006941 77 43 0,000 0,20825909 0,22611524 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20825909 0,22601325 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,2125503 0,23056629 ! hexose transport GO:0008645 67 44 0,000 0,2125503 0,23046238 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 0,000 0,2125503 0,23035857 ! maintenance of location in cell GO:0051651 97 44 0,000 0,2125503 0,23025485 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,21681839 0,23477275 ! glycolysis GO:0006096 65 45 0,000 0,21681839 0,23466714 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,21681839 0,23456162 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,21681839 0,2344562 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,21681839 0,23435088 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,21681839 0,23424564 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,21681839 0,23414051 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,22106349 0,23861766 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,22106349 0,23851065 ! response to insulin stimulus GO:0032868 95 46 0,000 0,22106349 0,23840375 ! positive regulation of defense response GO:0031349 76 47 0,000 0,22528572 0,24284832 ! endosome transport GO:0016197 108 47 0,000 0,22528572 0,24273956 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,22528572 0,2426309 ! JNK cascade GO:0007254 91 47 0,000 0,22528572 0,24252234 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,22528572 0,24241388 ! protein homooligomerization GO:0051260 76 47 0,000 0,22528572 0,24230552 ! Notch signaling pathway GO:0007219 96 48 0,000 0,2294852 0,24671197 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,2294852 0,24660178 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,2294852 0,24649169 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,2294852 0,2463817 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,2294852 0,24627181 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,23366206 0,2506424 ! regulation of action potential GO:0001508 95 49 0,000 0,23366206 0,25053071 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,23366206 0,25041911 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,23366206 0,25030762 ! regulation of ion transport GO:0043269 77 49 0,000 0,23366206 0,25019622 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,23366206 0,25008493 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,23366206 0,24997373 ! endocrine system development GO:0035270 104 49 0,000 0,23366206 0,24986263 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,23366206 0,24975163 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,23366206 0,24964073 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,23366206 0,24952992 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,23781641 0,25385372 ! neuromuscular process GO:0050905 99 50 0,000 0,23781641 0,25374115 ! inner ear development GO:0048839 79 50 0,000 0,23781641 0,25362867 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,23781641 0,2535163 ! viral infectious cycle GO:0019058 99 51 0,000 0,24194838 0,25780682 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,24194838 0,2576927 ! excretion GO:0007588 83 51 0,000 0,24194838 0,25757867 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,24194838 0,25746475 ! chromatin remodeling GO:0006338 109 51 0,000 0,24194838 0,25735093 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,24605809 0,26160661 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,24605809 0,26149106 ! membrane fusion GO:0006944 110 52 0,000 0,24605809 0,26137561 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,25014565 0,26560037 ! RNA catabolic process GO:0006401 93 53 0,000 0,25014565 0,26548321 ! regulation of translational initiation GO:0006446 82 53 0,000 0,25014565 0,26536615 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,25014565 0,2652492 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,25014565 0,26513235 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,25014565 0,2650156 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,25014565 0,26489896 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,25421118 0,26908584 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,25421118 0,26896751 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,25421118 0,26884928 ! cell recognition GO:0008037 85 54 0,000 0,25421118 0,26873115 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,25421118 0,26861313 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,25421118 0,26849522 ! chloride transport GO:0006821 90 55 0,000 0,25825481 0,27264637 ! glucose catabolic process GO:0006007 82 55 0,000 0,25825481 0,27252679 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,25825481 0,27240731 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,25825481 0,27228794 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,25825481 0,27216867 ! gastrulation GO:0007369 112 55 0,000 0,25825481 0,27204951 ! RNA elongation GO:0006354 79 55 0,000 0,25825481 0,27193045 ! regulation of actin filament length GO:0030832 105 56 0,000 0,26227665 0,27604445 ! sensory perception of smell GO:0007608 80 56 0,000 0,26227665 0,27592375 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,26227665 0,27580315 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,26227665 0,27568266 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,26227665 0,27556228 ! regulation of DNA replication GO:0006275 101 56 0,000 0,26227665 0,275442 ! proton transport GO:0015992 94 56 0,000 0,26227665 0,27532182 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,26227665 0,27520175 ! muscle fiber development GO:0048747 112 57 0,000 0,26627681 0,27927725 ! lipid modification GO:0030258 97 57 0,000 0,26627681 0,27915556 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,26627681 0,27903398 ! maintenance of location GO:0051235 118 57 0,000 0,26627681 0,2789125 ! hydrogen transport GO:0006818 97 58 0,000 0,27025542 0,28295672 ! regulation of endocytosis GO:0030100 91 58 0,000 0,27025542 0,28283364 ! adult behavior GO:0030534 99 58 0,000 0,27025542 0,28271067 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,27025542 0,2825878 ! positive regulation of secretion GO:0051047 95 59 0,000 0,27421258 0,28660098 ! regulation of cellular component size GO:0032535 109 59 0,000 0,27421258 0,28647654 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,27421258 0,2863522 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,27421258 0,28622797 ! establishment of organelle localization GO:0051656 109 59 0,000 0,27421258 0,28610385 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,27814842 0,29008456 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,27814842 0,28995888 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,27814842 0,2898333 ! camera-type eye development GO:0043010 116 60 0,000 0,27814842 0,28970783 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,28206304 0,29365801 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,28206304 0,293531 ! mesoderm development GO:0007498 119 61 0,000 0,28206304 0,29340409 ! tRNA processing GO:0008033 89 61 0,000 0,28206304 0,2932773 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,28206304 0,29315061 ! viral reproductive process GO:0022415 126 62 0,000 0,28595656 0,29706886 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,28595656 0,29694065 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,2898291 0,3008321 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,2898291 0,30070238 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,29368076 0,3045672 ! single fertilization GO:0007338 75 64 0,000 0,29368076 0,30443598 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,29751166 0,30827436 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,29751166 0,30814165 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,30132191 0,31195375 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,30132191 0,31181958 ! chromosome segregation GO:0007059 113 67 0,000 0,30511162 0,31560557 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,30511162 0,31546994 ! hexose catabolic process GO:0019320 104 67 0,000 0,30511162 0,31533443 ! activation of immune response GO:0002253 105 67 0,000 0,30511162 0,31519903 ! amino acid transport GO:0006865 125 68 0,000 0,3088809 0,31895598 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,3088809 0,31881915 ! viral reproduction GO:0016032 134 68 0,000 0,3088809 0,31868243 ! regulation of lipase activity GO:0060191 130 68 0,000 0,3088809 0,31854584 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,3088809 0,31840935 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,31262985 0,32213594 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,31262985 0,32199804 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,31262985 0,32186026 ! antigen processing and presentation GO:0019882 104 69 0,000 0,31262985 0,32172259 ! amine catabolic process GO:0009310 117 71 0,000 0,32006724 0,32923548 ! regulation of immune effector process GO:0002697 137 71 0,000 0,32006724 0,32909478 ! acute inflammatory response GO:0002526 113 72 0,000 0,32375588 0,33274526 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,32375588 0,33260318 ! carbohydrate transport GO:0008643 110 72 0,000 0,32375588 0,33246123 ! regulation of blood pressure GO:0008217 125 73 0,000 0,32742464 0,33608519 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,32742464 0,33594187 ! axon guidance GO:0007411 139 73 0,000 0,32742464 0,33579867 ! fertilization GO:0009566 90 73 0,000 0,32742464 0,3356556 ! transition metal ion transport GO:0000041 126 74 0,000 0,33107362 0,33925175 ! neurotransmitter transport GO:0006836 123 74 0,000 0,33107362 0,33910733 ! meiosis GO:0007126 121 74 0,000 0,33107362 0,33896303 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,33107362 0,33881885 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,33107362 0,3386748 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,33107362 0,33853086 ! organelle localization GO:0051640 136 74 0,000 0,33107362 0,33838705 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,33470291 0,34195126 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,33470291 0,34180612 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,33470291 0,3416611 ! meiotic cell cycle GO:0051321 122 75 0,000 0,33470291 0,3415162 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,33831264 0,34505308 ! defense response to bacterium GO:0042742 89 76 0,000 0,33831264 0,34490687 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,33831264 0,34476078 ! regulation of catabolic process GO:0009894 161 76 0,000 0,33831264 0,34461482 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,3419029 0,34812458 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,3419029 0,34797732 ! blood coagulation GO:0007596 146 78 0,000 0,3454738 0,35146299 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,3454738 0,35131444 ! protein oligomerization GO:0051259 139 78 0,000 0,3454738 0,35116602 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,34902544 0,35462636 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,35255793 0,35806432 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,35255793 0,35791324 ! inorganic anion transport GO:0015698 138 80 0,000 0,35255793 0,35776229 ! digestion GO:0007586 112 81 0,000 0,35607137 0,36117526 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,35956585 0,36456614 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,35956585 0,36441257 ! regulation of lyase activity GO:0051339 160 83 0,000 0,36304149 0,36778014 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,36649838 0,37112588 ! hemostasis GO:0007599 158 84 0,000 0,36649838 0,37096975 ! negative regulation of transport GO:0051051 153 84 0,000 0,36649838 0,37081375 ! nucleosome assembly GO:0006334 122 85 0,000 0,36993662 0,37413515 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,37335632 0,377435 ! chromatin assembly GO:0031497 124 86 0,000 0,37335632 0,37727648 ! alcohol catabolic process GO:0046164 130 86 0,000 0,37335632 0,3771181 ! amine transport GO:0015837 155 86 0,000 0,37335632 0,37695984 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,37675757 0,38023436 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,37675757 0,38007493 ! cellular respiration GO:0045333 135 88 0,000 0,38014047 0,38332689 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,38014047 0,3831663 ! cellular defense response GO:0006968 114 89 0,000 0,38350512 0,38639586 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,38685162 0,38960443 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,38685162 0,38944142 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,39018006 0,39262787 ! regulation of defense response GO:0031347 149 92 0,000 0,39349055 0,39579359 ! nucleosome organization GO:0034728 138 92 0,000 0,39349055 0,39562819 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,39349055 0,39546293 ! vitamin metabolic process GO:0006766 139 92 0,000 0,39349055 0,39529781 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,39678317 0,3984392 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,39678317 0,39827297 ! forebrain development GO:0030900 188 95 0,000 0,40331522 0,40466072 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,40331522 0,40449205 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,40655483 0,40757122 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,40977696 0,41063031 ! protein ubiquitination GO:0016567 217 97 0,000 0,40977696 0,41045935 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,4129817 0,41349728 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,4129817 0,41332528 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,41616915 0,41634219 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,41616915 0,41616915