pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/532-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of lipid kinase activity GO:0043550 13 7 5,000 2,22E-14 5,34E-11 ! lung development GO:0030324 144 67 7,000 2,348E-10 2,825E-07 ! respiratory tube development GO:0030323 150 70 7,000 3,366E-10 2,699E-07 ! respiratory system development GO:0060541 153 72 7,000 4,24E-10 2,55E-07 ! positive regulation of pseudopodium assembly GO:0031274 14 6 3,000 3,338E-09 1,606E-06 GO:0031272|regulation of pseudopodium assembly, ! auditory receptor cell differentiation GO:0042491 32 16 4,000 3,577E-09 1,434E-06 ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 3,996E-09 1,373E-06 ! interphase GO:0051325 213 98 7,000 5,123E-09 1,541E-06 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 1,254E-08 3,352E-06 ! trophectodermal cell differentiation GO:0001829 13 8 3,000 1,548E-08 3,726E-06 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 1,641E-08 3,588E-06 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 2,116E-08 4,244E-06 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 2,288E-08 4,234E-06 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 2,622E-08 4,507E-06 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 3,000 2,779E-08 4,457E-06 ! blastocyst formation GO:0001825 17 10 3,000 4,617E-08 6,943E-06 ! positive regulation of cell migration GO:0030335 126 57 5,000 9,81E-08 1,388E-05 ! regulation of cell projection assembly GO:0060491 30 12 3,000 1,082E-07 1,446E-05 ! cell cycle arrest GO:0007050 213 100 6,000 1,403E-07 1,776E-05 ! ear development GO:0043583 103 62 5,000 1,636E-07 1,968E-05 ! regulation of homeostatic process GO:0032844 134 62 5,000 1,636E-07 1,874E-05 ! regulation of lipid metabolic process GO:0019216 115 63 5,000 1,802E-07 1,971E-05 ! positive regulation of cell motion GO:0051272 146 64 5,000 1,982E-07 2,073E-05 ! regulation of erythrocyte differentiation GO:0045646 44 14 3,000 2,174E-07 2,18E-05 ! positive regulation of glycolysis GO:0045821 14 5 2,000 5,83E-07 5,61E-05 ! regulation of myeloid cell differentiation GO:0045637 98 42 4,000 6,422E-07 5,943E-05 ! G1 phase GO:0051318 40 19 3,000 8,293E-07 7,39E-05 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 3,000 8,293E-07 7,126E-05 ! regulation of gene-specific transcription GO:0032583 96 46 4,000 1,022E-06 8,479E-05 ! nuclear migration GO:0007097 12 6 2,000 1,163E-06 9,324E-05 ! inner ear development GO:0048839 79 50 4,000 1,56E-06 1,211E-04 ! macrophage differentiation GO:0030225 11 7 2,000 2,029E-06 1,525E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 2,352E-06 1,715E-04 ! Golgi vesicle transport GO:0048193 207 99 5,000 2,65E-06 1,875E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 3,132E-06 2,153E-04 ! blastocyst development GO:0001824 49 26 3,000 3,132E-06 2,093E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 3,237E-06 2,105E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 3,237E-06 2,049E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 3,237E-06 1,997E-04 ! establishment of organelle localization GO:0051656 109 59 4,000 3,584E-06 2,156E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 3,665E-06 2,151E-04 ! positive regulation of cell projection organization GO:0031346 58 27 3,000 3,665E-06 2,1E-04 ! regulation of developmental growth GO:0048638 15 9 2,000 4,841E-06 2,709E-04 ! positive regulation of glucose metabolic process GO:0010907 18 9 2,000 4,841E-06 2,647E-04 ! regulation of glycolysis GO:0006110 21 9 2,000 4,841E-06 2,588E-04 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 2,000 4,841E-06 2,532E-04 ! lung alveolus development GO:0048286 26 10 2,000 6,896E-06 3,53E-04 ! protein sumoylation GO:0016925 15 10 2,000 6,896E-06 3,457E-04 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 2,000 6,896E-06 3,386E-04 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 6,896E-06 3,318E-04 ! positive regulation of gene-specific transcription GO:0043193 65 33 3,000 8,392E-06 3,959E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 9,455E-06 4,375E-04 ! nucleus localization GO:0051647 19 11 2,000 9,455E-06 4,292E-04 ! organelle localization GO:0051640 136 74 4,000 1,101E-05 4,904E-04 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 1,257E-05 5,499E-04 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 1,338E-05 5,749E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 2,000 1,629E-05 6,878E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! embryonic placenta development GO:0001892 23 13 2,000 1,629E-05 6,76E-04 ! response to hypoxia GO:0001666 171 81 4,000 1,713E-05 6,984E-04 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,818E-05 7,291E-04 ! response to oxygen levels GO:0070482 176 83 4,000 1,929E-05 7,608E-04 ! negative regulation of growth GO:0045926 155 84 4,000 2,044E-05 7,934E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 2,068E-05 7,898E-04 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 2,000 2,578E-05 9,69E-04 ! muscle maintenance GO:0046716 26 15 2,000 2,578E-05 9,541E-04 ! regulation of glucose metabolic process GO:0010906 28 16 2,000 3,163E-05 1,153E-03 ! G1 phase of mitotic cell cycle GO:0000080 35 16 2,000 3,163E-05 1,136E-03 ! filopodium assembly GO:0046847 32 16 2,000 3,163E-05 1,119E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 3,218E-05 1,122E-03 ! heart looping GO:0001947 30 17 2,000 3,83E-05 1,316E-03 ! microspike assembly GO:0030035 36 17 2,000 3,83E-05 1,298E-03 ! regulation of muscle cell differentiation GO:0051147 33 17 2,000 3,83E-05 1,28E-03 ! regulation of cell projection organization GO:0031344 121 50 3,000 4,486E-05 1,479E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 2,000 4,583E-05 1,49E-03 ! regulation of cell shape GO:0008360 125 51 3,000 4,854E-05 1,557E-03 ! positive regulation of growth GO:0045927 90 52 3,000 5,242E-05 1,66E-03 ! response to UV GO:0009411 104 53 3,000 5,653E-05 1,766E-03 ! regulation of carbohydrate metabolic process GO:0006109 38 20 2,000 6,366E-05 1,964E-03 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 6,366E-05 1,939E-03 ! heart morphogenesis GO:0003007 97 55 3,000 6,544E-05 1,968E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 7,027E-05 2,087E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 9,806E-05 2,877E-03 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 2,000 9,806E-05 2,842E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 9,834E-05 2,817E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 1,117E-04 3,163E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 1,117E-04 3,126E-03 ! protein tetramerization GO:0051262 52 24 2,000 1,117E-04 3,09E-03 ! myeloid cell differentiation GO:0030099 111 65 3,000 1,261E-04 3,447E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 1,266E-04 3,423E-03 ! vasculogenesis GO:0001570 46 25 2,000 1,266E-04 3,385E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,266E-04 3,348E-03 ! interaction with host GO:0051701 62 25 2,000 1,266E-04 3,311E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,419E-04 3,67E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 1,427E-04 3,653E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 1,427E-04 3,615E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 1,427E-04 3,577E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 1,51E-04 3,747E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,51E-04 3,708E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,51E-04 3,671E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,51E-04 3,634E-03 ! positive regulation of muscle cell differentiation GO:0051149 13 5 1,000 1,51E-04 3,598E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 1,51E-04 3,563E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,51E-04 3,528E-03 ! valine metabolic process GO:0006573 10 5 1,000 1,51E-04 3,494E-03 ! mRNA transcription GO:0009299 9 5 1,000 1,51E-04 3,461E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,51E-04 3,428E-03 ! decidualization GO:0046697 11 5 1,000 1,51E-04 3,396E-03 ! mitotic recombination GO:0006312 9 5 1,000 1,51E-04 3,365E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 1,51E-04 3,334E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 1,51E-04 3,304E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 1,59E-04 3,447E-03 ! regulation of chromosome organization GO:0033044 42 27 2,000 1,601E-04 3,44E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,788E-04 3,807E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 1,788E-04 3,774E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 1,989E-04 4,161E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 1,989E-04 4,125E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,989E-04 4,09E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 2,26E-04 4,608E-03 ! embryonic hemopoiesis GO:0035162 14 6 1,000 2,26E-04 4,569E-03 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 2,26E-04 4,531E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 2,26E-04 4,494E-03 ! male sex determination GO:0030238 15 6 1,000 2,26E-04 4,457E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 2,26E-04 4,421E-03 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 2,26E-04 4,385E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,26E-04 4,35E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 2,26E-04 4,315E-03 ! maternal placenta development GO:0001893 12 6 1,000 2,26E-04 4,281E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 2,433E-04 4,572E-03 ! protein oligomerization GO:0051259 139 78 3,000 2,554E-04 4,763E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 2,677E-04 4,954E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 3,156E-04 5,796E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,156E-04 5,752E-03 ! mRNA stabilization GO:0048255 18 7 1,000 3,156E-04 5,709E-03 GO:0043489|RNA stabilization, ! B cell lineage commitment GO:0002326 21 7 1,000 3,156E-04 5,666E-03 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 3,156E-04 5,624E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 3,156E-04 5,583E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,156E-04 5,542E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 3,156E-04 5,502E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,156E-04 5,462E-03 ! oxygen homeostasis GO:0032364 12 7 1,000 3,156E-04 5,423E-03 ! response to tumor cell GO:0002347 13 7 1,000 3,156E-04 5,385E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 3,156E-04 5,347E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 3,156E-04 5,31E-03 ! placenta development GO:0001890 53 34 2,000 3,211E-04 5,365E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 3,211E-04 5,328E-03 ! meiosis I GO:0007127 65 37 2,000 4,134E-04 6,812E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 4,134E-04 6,765E-03 ! tissue remodeling GO:0048771 76 37 2,000 4,134E-04 6,72E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,197E-04 6,777E-03 ! succinate metabolic process GO:0006105 14 8 1,000 4,197E-04 6,732E-03 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 4,197E-04 6,687E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 4,197E-04 6,643E-03 ! hemoglobin metabolic process GO:0020027 13 8 1,000 4,197E-04 6,6E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,197E-04 6,557E-03 ! ER overload response GO:0006983 12 8 1,000 4,197E-04 6,515E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 4,197E-04 6,473E-03 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 4,197E-04 6,432E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 4,197E-04 6,391E-03 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 4,197E-04 6,351E-03 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 4,229E-04 6,36E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 4,475E-04 6,688E-03 ! carbohydrate homeostasis GO:0033500 53 38 2,000 4,475E-04 6,646E-03 GO:0042593|glucose homeostasis, ! multicellular organismal metabolic process GO:0044236 57 40 2,000 5,211E-04 7,692E-03 ! induction of positive chemotaxis GO:0050930 15 9 1,000 5,382E-04 7,896E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,382E-04 7,848E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 1,000 5,382E-04 7,801E-03 ! phosphagen metabolic process GO:0006599 12 9 1,000 5,382E-04 7,754E-03 GO:0006600|creatine metabolic process, ! protein heterooligomerization GO:0051291 16 9 1,000 5,382E-04 7,708E-03 ! gas homeostasis GO:0033483 16 9 1,000 5,382E-04 7,662E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 5,382E-04 7,617E-03 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 5,382E-04 7,573E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 5,382E-04 7,529E-03 ! leukocyte differentiation GO:0002521 202 96 3,000 5,634E-04 7,836E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 6,71E-04 9,279E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 6,71E-04 9,226E-03 ! COPI coating of Golgi vesicle GO:0048205 19 10 1,000 6,71E-04 9,173E-03 GO:0048200|Golgi transport vesicle coating, ! positive regulation of muscle contraction GO:0045933 14 10 1,000 6,71E-04 9,122E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 6,71E-04 9,07E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 6,71E-04 9,02E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 6,71E-04 8,97E-03 ! apical protein localization GO:0045176 15 10 1,000 6,71E-04 8,92E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 6,71E-04 8,871E-03 ! double-strand break repair GO:0006302 81 44 2,000 6,906E-04 9,08E-03 ! pigmentation GO:0043473 100 46 2,000 7,871E-04 0,01029221 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 8,181E-04 0,01063916 ! Golgi vesicle budding GO:0048194 22 11 1,000 8,181E-04 0,01058196 ! detection of mechanical stimulus GO:0050982 22 11 1,000 8,181E-04 0,01052537 ! blood vessel remodeling GO:0001974 29 11 1,000 8,181E-04 0,01046939 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 8,181E-04 0,01041399 ! regulation of intracellular pH GO:0051453 19 11 1,000 8,181E-04 0,01035918 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 8,181E-04 0,01030495 ! DNA methylation GO:0006306 19 11 1,000 8,181E-04 0,01025127 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 8,181E-04 0,01019816 ! regulation of embryonic development GO:0045995 27 11 1,000 8,181E-04 0,01014559 ! positive regulation of cell cycle GO:0045787 89 48 2,000 8,917E-04 0,01100253 ! activation of caspase activity GO:0006919 84 48 2,000 8,917E-04 0,01094639 ! virus-host interaction GO:0019048 29 12 1,000 9,792E-04 0,0119586 ! regulation of B cell proliferation GO:0030888 20 12 1,000 9,792E-04 0,01189821 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 9,792E-04 0,01183842 GO:0050927|positive regulation of positive chemotaxis, ! asymmetric protein localization GO:0008105 20 12 1,000 9,792E-04 0,01177922 ! entry into host cell GO:0030260 32 12 1,000 9,792E-04 0,01172062 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 9,792E-04 0,0116626 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 9,792E-04 0,01160515 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,792E-04 0,01154826 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 9,792E-04 0,01149193 ! histone modification GO:0016570 91 50 2,000 1,005E-03 0,01173541 ! covalent chromatin modification GO:0016569 101 52 2,000 1,127E-03 0,01309362 ! regulation of chemokine production GO:0032642 18 13 1,000 1,154E-03 0,01335121 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 1,154E-03 0,01328733 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 25 13 1,000 1,154E-03 0,01322406 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,154E-03 0,01316138 ! regulation of cellular pH GO:0030641 22 13 1,000 1,154E-03 0,0130993 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,154E-03 0,0130378 ! regulation of mRNA stability GO:0043488 31 13 1,000 1,154E-03 0,01297688 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,326E-03 0,01483799 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 1,326E-03 0,0147693 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,343E-03 0,01489217 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 1,000 1,343E-03 0,01482386 ! response to gamma radiation GO:0010332 28 14 1,000 1,343E-03 0,01475617 ! regulation of RNA stability GO:0043487 32 14 1,000 1,343E-03 0,0146891 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 1,47E-03 0,0160083 ! regulation of bone remodeling GO:0046850 137 57 2,000 1,47E-03 0,01593619 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,546E-03 0,01667816 ! vesicle coating GO:0006901 33 15 1,000 1,546E-03 0,0166037 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,546E-03 0,01652991 ! histone deacetylation GO:0016575 20 15 1,000 1,546E-03 0,01645677 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 1,546E-03 0,01638427 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 1,546E-03 0,01631241 ! regulation of tissue remodeling GO:0034103 140 58 2,000 1,546E-03 0,0162455 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,762E-03 0,01843337 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,762E-03 0,01835357 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,788E-03 0,01854476 ! viral reproductive process GO:0022415 126 62 2,000 1,874E-03 0,01934905 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,992E-03 0,02048153 ! endothelial cell migration GO:0043542 28 17 1,000 1,992E-03 0,02039437 ! myoblast differentiation GO:0045445 45 17 1,000 1,992E-03 0,02030796 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,992E-03 0,02022227 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,992E-03 0,0201373 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 1,992E-03 0,02005305 ! membrane budding GO:0006900 37 17 1,000 1,992E-03 0,01996949 ! DNA unwinding during replication GO:0006268 27 17 1,000 1,992E-03 0,01988663 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 1,992E-03 0,01980445 ! neural crest cell migration GO:0001755 37 17 1,000 1,992E-03 0,01972296 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 1,992E-03 0,01964212 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,992E-03 0,01956195 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,235E-03 0,0218617 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 2,235E-03 0,02177319 ! cell projection assembly GO:0030031 120 66 2,000 2,242E-03 0,02174687 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 2,34E-03 0,02261058 ! activation of MAPK activity GO:0000187 115 67 2,000 2,34E-03 0,02252013 ! negative regulation of kinase activity GO:0033673 131 68 2,000 2,441E-03 0,02339918 ! viral reproduction GO:0016032 134 68 2,000 2,441E-03 0,02330633 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 2,492E-03 0,02369692 ! lipid phosphorylation GO:0046834 35 19 1,000 2,492E-03 0,02360363 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 2,492E-03 0,02351106 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,492E-03 0,02341922 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of endothelial cell migration GO:0010594 44 19 1,000 2,492E-03 0,0233281 ! cellular pigmentation GO:0033059 36 19 1,000 2,492E-03 0,02323768 ! cell cycle checkpoint GO:0000075 137 69 2,000 2,545E-03 0,02364002 ! protein amino acid deacetylation GO:0006476 29 20 1,000 2,762E-03 0,02555557 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,762E-03 0,02545766 ! response to alkaloid GO:0043279 38 20 1,000 2,762E-03 0,02536049 ! DNA duplex unwinding GO:0032508 31 20 1,000 2,762E-03 0,02526406 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 1,000 2,762E-03 0,02516837 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,762E-03 0,02507339 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,762E-03 0,02497913 ! regulation of caspase activity GO:0043281 122 72 2,000 2,872E-03 0,02588202 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 2,872E-03 0,02578544 ! negative regulation of transferase activity GO:0051348 140 72 2,000 2,872E-03 0,02568959 ! reciprocal meiotic recombination GO:0007131 39 21 1,000 3,045E-03 0,02713003 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 3,045E-03 0,02702992 ! cell aging GO:0007569 44 21 1,000 3,045E-03 0,02693054 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 3,045E-03 0,02683189 ! DNA modification GO:0006304 34 21 1,000 3,045E-03 0,02673397 ! positive regulation of locomotion GO:0040017 39 21 1,000 3,045E-03 0,02663675 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! response to cytokine stimulus GO:0034097 63 21 1,000 3,045E-03 0,02654024 ! meiosis GO:0007126 121 74 2,000 3,104E-03 0,02696286 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 3,104E-03 0,02686587 ! meiotic cell cycle GO:0051321 122 75 2,000 3,224E-03 0,02780608 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 3,34E-03 0,02870373 ! regulation of chemotaxis GO:0050920 40 22 1,000 3,34E-03 0,02860158 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,34E-03 0,02850016 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,34E-03 0,02839945 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 3,34E-03 0,02829945 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,34E-03 0,02820015 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,34E-03 0,02810155 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 3,34E-03 0,02800364 ! regulation of catabolic process GO:0009894 161 76 2,000 3,347E-03 0,0279648 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,649E-03 0,03038065 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 3,649E-03 0,03027589 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,649E-03 0,03017185 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 3,649E-03 0,03006852 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 3,649E-03 0,0299659 ! vesicle targeting GO:0006903 43 23 1,000 3,649E-03 0,02986397 ! sex determination GO:0007530 47 23 1,000 3,649E-03 0,02976274 ! regulation of peptidase activity GO:0052547 134 79 2,000 3,734E-03 0,0303479 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 3,734E-03 0,03024572 ! muscle cell differentiation GO:0042692 159 80 2,000 3,868E-03 0,03123013 ! protein import into nucleus GO:0006606 158 80 2,000 3,868E-03 0,03112568 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 3,971E-03 0,03184583 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 3,971E-03 0,03174003 ! regulation of behavior GO:0050795 43 24 1,000 3,971E-03 0,03163493 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 3,971E-03 0,03153052 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 3,971E-03 0,0314268 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 4,005E-03 0,0315974 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 2,000 4,005E-03 0,03149414 ! response to drug GO:0042493 143 82 2,000 4,146E-03 0,03249156 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 4,305E-03 0,03362993 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 4,305E-03 0,03352109 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,305E-03 0,03341296 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 4,305E-03 0,03330552 ! negative regulation of DNA replication GO:0008156 42 25 1,000 4,305E-03 0,03319877 ! response to starvation GO:0042594 42 25 1,000 4,305E-03 0,03309271 ! neural crest cell development GO:0014032 54 25 1,000 4,305E-03 0,03298732 GO:0014033|neural crest cell differentiation, ! negative regulation of cell development GO:0010721 73 25 1,000 4,305E-03 0,0328826 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 4,305E-03 0,03277854 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,305E-03 0,03267513 ! initiation of viral infection GO:0019059 57 26 1,000 4,652E-03 0,03519676 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 4,652E-03 0,03508642 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 4,652E-03 0,03497678 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 4,652E-03 0,03486782 ! mitochondrion organization GO:0007005 148 86 2,000 4,737E-03 0,0353954 ! protein localization in nucleus GO:0034504 176 87 2,000 4,892E-03 0,03644284 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 5,011E-03 0,03721344 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,011E-03 0,03709894 ! protein amino acid acylation GO:0043543 55 27 1,000 5,011E-03 0,03698514 ! fat cell differentiation GO:0045444 50 27 1,000 5,011E-03 0,03687204 ! mitochondrial membrane organization GO:0007006 57 27 1,000 5,011E-03 0,03675962 ! response to toxin GO:0009636 47 27 1,000 5,011E-03 0,03664789 ! base-excision repair GO:0006284 41 27 1,000 5,011E-03 0,03653684 ! positive regulation of protein modification process GO:0031401 136 88 2,000 5,051E-03 0,03671324 ! regulation of pH GO:0006885 43 29 1,000 5,767E-03 0,04179357 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 5,889E-03 0,04254837 ! transcription initiation GO:0006352 153 94 2,000 6,066E-03 0,04369591 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 6,163E-03 0,04426478 ! regulation of B cell activation GO:0050864 50 30 1,000 6,163E-03 0,04413304 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 6,571E-03 0,04691693 ! collagen metabolic process GO:0032963 45 31 1,000 6,571E-03 0,04677813 ! erythrocyte differentiation GO:0030218 55 31 1,000 6,571E-03 0,04664014 ! spindle organization GO:0007051 46 32 1,000 6,992E-03 0,04947689 ! response to ionizing radiation GO:0010212 65 32 1,000 6,992E-03 0,04933179 ! response to mechanical stimulus GO:0009612 57 32 1,000 6,992E-03 0,04918755 ! skeletal muscle tissue development GO:0007519 186 99 2,000 6,998E-03 0,04909066 GO:0060538|skeletal muscle organ development, ! DNA damage checkpoint GO:0000077 71 33 1,000 7,424E-03 0,05192404 ! establishment of vesicle localization GO:0051650 61 33 1,000 7,424E-03 0,05177354 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 7,868E-03 0,05471085 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 7,868E-03 0,05455318 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 7,868E-03 0,05439642 ! regulation of muscle development GO:0048634 70 35 1,000 8,323E-03 0,05738156 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 8,323E-03 0,05721761 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 8,323E-03 0,0570546 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 8,323E-03 0,05689251 ! vesicle localization GO:0051648 64 35 1,000 8,323E-03 0,05673134 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 8,791E-03 0,0597465 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 8,791E-03 0,0595782 ! DNA integrity checkpoint GO:0031570 75 36 1,000 8,791E-03 0,05941085 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 8,791E-03 0,05924443 ! embryonic organ development GO:0048568 57 36 1,000 8,791E-03 0,05907894 ! sister chromatid segregation GO:0000819 58 37 1,000 9,269E-03 0,06212261 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 9,269E-03 0,06195005 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 9,759E-03 0,06504488 ! nucleus organization GO:0006997 67 38 1,000 9,759E-03 0,0648652 ! erythrocyte homeostasis GO:0034101 64 38 1,000 9,759E-03 0,06468651 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 9,759E-03 0,0645088 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,01026084 0,06763722 ! ear morphogenesis GO:0042471 60 39 1,000 0,01026084 0,06745242 ! segmentation GO:0035282 67 39 1,000 0,01026084 0,06726863 ! Rho protein signal transduction GO:0007266 74 39 1,000 0,01026084 0,06708583 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01077346 0,07024646 ! mesenchymal cell development GO:0014031 87 40 1,000 0,01077346 0,0700566 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 1,000 0,01077346 0,06986777 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01129719 0,07306732 ! gliogenesis GO:0042063 88 41 1,000 0,01129719 0,07287143 ! T cell differentiation GO:0030217 81 41 1,000 0,01129719 0,07267659 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01183195 0,07591378 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01183195 0,07571188 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01237763 0,0789936 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01237763 0,07878462 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01237763 0,07857675 ! biopolymer methylation GO:0043414 84 44 1,000 0,01293416 0,08189364 ! B cell differentiation GO:0030183 107 44 1,000 0,01293416 0,0816787 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01293416 0,08146488 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01350143 0,08481575 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01350143 0,08459488 ! response to calcium ion GO:0051592 81 47 1,000 0,01466784 0,09166447 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01466784 0,09142699 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,01466784 0,09119075 ! methylation GO:0032259 90 47 1,000 0,01466784 0,09095572 ! protein homooligomerization GO:0051260 76 47 1,000 0,01466784 0,0907219 ! mitochondrial transport GO:0006839 82 48 1,000 0,0152668 0,09418441 ! cellular component disassembly GO:0022411 86 48 1,000 0,0152668 0,09394353 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,0152668 0,09370388 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,01587615 0,09719594 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01587615 0,09694925 ! regulation of ossification GO:0030278 117 50 1,000 0,01649579 0,10047813 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01649579 0,10022439 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,01649579 0,09997194 ! positive regulation of binding GO:0051099 78 51 1,000 0,01712563 0,10352832 ! viral infectious cycle GO:0019058 99 51 1,000 0,01712563 0,10326885 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,01712563 0,10301068 ! vesicle organization GO:0016050 107 51 1,000 0,01712563 0,10275379 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01712563 0,10249819 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 1,000 0,0177656 0,10606458 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,0177656 0,10580205 ! amino acid activation GO:0043038 92 52 1,000 0,0177656 0,10554081 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 0,0177656 0,10528085 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01841559 0,10886466 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01943863 0,11463077 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01943863 0,1143505 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01943863 0,1140716 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01943863 0,11379405 ! neuron fate determination GO:0048664 7 5 0,000 0,01943863 0,11351785 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01943863 0,11324299 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01943863 0,11296945 ! polyol transport GO:0015791 12 5 0,000 0,01943863 0,11269724 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01943863 0,11242633 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01943863 0,11215672 ! response to superoxide GO:0000303 10 5 0,000 0,01943863 0,11188841 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01943863 0,11162137 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01943863 0,11135561 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01943863 0,1110911 ! female meiosis GO:0007143 7 5 0,000 0,01943863 0,11082785 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01943863 0,11056585 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01943863 0,11030508 ! cobalt ion transport GO:0006824 11 5 0,000 0,01943863 0,11004554 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01943863 0,10978722 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01943863 0,1095301 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01943863 0,10927419 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01943863 0,10901947 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01943863 0,10876594 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01943863 0,10851358 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01943863 0,10826239 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01943863 0,10801237 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01943863 0,10776349 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01943863 0,10751576 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01943863 0,10726916 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01943863 0,10702369 ! negative chemotaxis GO:0050919 14 5 0,000 0,01943863 0,10677935 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01943863 0,10653611 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01943863 0,10629399 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01943863 0,10605296 ! behavioral response to pain GO:0048266 9 5 0,000 0,01943863 0,10581302 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01943863 0,10557416 ! Notch receptor processing GO:0007220 8 5 0,000 0,01943863 0,10533638 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01943863 0,10509967 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01943863 0,10486402 ! micturition GO:0060073 9 5 0,000 0,01943863 0,10462943 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01943863 0,10439588 ! copulation GO:0007620 9 5 0,000 0,01943863 0,10416337 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01943863 0,1039319 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01943863 0,10370145 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01943863 0,10347202 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01943863 0,10324361 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01943863 0,1030162 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01943863 0,10278979 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01943863 0,10256437 ! grooming behavior GO:0007625 6 5 0,000 0,01943863 0,10233994 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01943863 0,10211649 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01943863 0,10189402 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01943863 0,10167251 ! response to protozoan GO:0001562 10 5 0,000 0,01943863 0,10145196 ! lymph vessel development GO:0001945 10 5 0,000 0,01943863 0,10123237 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01943863 0,10101372 ! endochondral ossification GO:0001958 16 5 0,000 0,01943863 0,10079602 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01943863 0,10057926 ! parathyroid gland development GO:0060017 13 5 0,000 0,01943863 0,10036342 ! anagen GO:0042640 6 5 0,000 0,01943863 0,10014851 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01943863 0,09993452 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01943863 0,09972144 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01943863 0,09950926 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01943863 0,09929799 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01943863 0,09908761 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01943863 0,09887813 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01943863 0,09866952 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01943863 0,0984618 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01943863 0,09825495 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01943863 0,09804896 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01943863 0,09784384 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01943863 0,09763957 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01943863 0,09743615 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01943863 0,09723358 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01943863 0,09703186 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01943863 0,09683096 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01943863 0,0966309 ! histidine catabolic process GO:0006548 6 5 0,000 0,01943863 0,09643166 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01943863 0,09623324 ! microvillus organization GO:0032528 7 5 0,000 0,01943863 0,09603563 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01943863 0,09583884 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01943863 0,09564285 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01943863 0,09544766 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01943863 0,09525327 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01943863 0,09505966 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01943863 0,09486684 ! polyol catabolic process GO:0046174 7 5 0,000 0,01943863 0,09467481 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01943863 0,09448354 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01943863 0,09429305 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01943863 0,09410333 ! muscle cell migration GO:0014812 8 5 0,000 0,01943863 0,09391437 ! mitochondrial fission GO:0000266 8 5 0,000 0,01943863 0,09372616 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01943863 0,09353871 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01943863 0,093352 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01943863 0,09316604 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01943863 0,09298082 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01943863 0,09279634 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01943863 0,09261258 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01943863 0,09242955 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01943863 0,09224725 ! response to food GO:0032094 6 5 0,000 0,01943863 0,09206566 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01943863 0,09188478 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01943863 0,09170462 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01943863 0,09152516 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01943863 0,09134639 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01943863 0,09116833 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01943863 0,09099096 ! forebrain neuron development GO:0021884 13 5 0,000 0,01943863 0,09081428 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01943863 0,09063828 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01943863 0,09046297 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01943863 0,09028833 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01943863 0,09011436 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01943863 0,08994107 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01943863 0,08976843 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01943863 0,08959646 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01943863 0,08942515 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01943863 0,08925449 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01943863 0,08908448 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01943863 0,08891512 ! basic amino acid transport GO:0015802 11 5 0,000 0,01943863 0,0887464 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01943863 0,08857832 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01943863 0,08841088 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01943863 0,08824406 ! depyrimidination GO:0045008 10 5 0,000 0,01943863 0,08807788 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01943863 0,08791232 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01943863 0,08774738 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01943863 0,08758306 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01943863 0,08741935 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01943863 0,08725626 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01943863 0,08709377 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01943863 0,08693189 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01943863 0,0867706 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01943863 0,08660992 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01943863 0,08644982 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01943863 0,08629032 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01943863 0,08613141 ! response to arsenic GO:0046685 10 5 0,000 0,01943863 0,08597308 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01943863 0,08581533 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01943863 0,08565816 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01943863 0,08550156 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01943863 0,08534554 ! response to cadmium ion GO:0046686 7 5 0,000 0,01943863 0,08519008 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01943863 0,08503519 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01943863 0,08488086 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01943863 0,08472709 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01943863 0,08457388 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01943863 0,08442122 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01943863 0,08426911 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01943863 0,08411754 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01943863 0,08396652 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01943863 0,08381605 ! neural tube patterning GO:0021532 7 5 0,000 0,01943863 0,08366611 ! embryonic cleavage GO:0040016 6 5 0,000 0,01943863 0,0835167 ! peroxisome fission GO:0016559 5 5 0,000 0,01943863 0,08336783 ! histone demethylation GO:0016577 10 5 0,000 0,01943863 0,08321949 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01943863 0,08307168 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01943863 0,08292439 ! metaphase plate congression GO:0051310 7 5 0,000 0,01943863 0,08277762 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01943863 0,08263137 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,01943863 0,08248563 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01943863 0,08234041 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01943863 0,0821957 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01943863 0,0820515 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01943863 0,0819078 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01943863 0,08176461 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01943863 0,08162191 ! plasminogen activation GO:0031639 5 5 0,000 0,01943863 0,08147971 ! B cell homeostasis GO:0001782 13 5 0,000 0,01943863 0,08133801 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01943863 0,0811968 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01943863 0,08105607 ! metaphase GO:0051323 8 5 0,000 0,01943863 0,08091584 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01943863 0,08077609 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01943863 0,08063682 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01943863 0,08049803 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01943863 0,08035972 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01943863 0,08022188 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01943863 0,08008451 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01943863 0,07994761 ! response to redox state GO:0051775 5 5 0,000 0,01943863 0,07981118 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01943863 0,07967522 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01943863 0,07953972 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01943863 0,07940468 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01943863 0,07927009 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01943863 0,07913596 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01943863 0,07900229 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01943863 0,07886906 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01943863 0,07873629 ! striatum development GO:0021756 9 5 0,000 0,01943863 0,07860396 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01943863 0,07847207 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01943863 0,07834063 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01943863 0,07820962 ! glial cell migration GO:0008347 11 5 0,000 0,01943863 0,07807906 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01943863 0,07794892 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01943863 0,07781922 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01943863 0,07768996 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01943863 0,07756112 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01943863 0,07743271 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01943863 0,07730472 ! neuroprotection GO:0043526 6 5 0,000 0,01943863 0,07717715 ! neural plate development GO:0001840 8 5 0,000 0,01943863 0,07705001 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01943863 0,07692328 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01943863 0,07679697 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01943863 0,07667107 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01943863 0,07654559 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01943863 0,07642051 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01943863 0,07629585 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01943863 0,07617159 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01943863 0,07604773 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01943863 0,07592428 ! spindle assembly GO:0051225 6 5 0,000 0,01943863 0,07580122 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01943863 0,07567857 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01943863 0,07555631 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01943863 0,07543444 ! drug metabolic process GO:0017144 6 5 0,000 0,01943863 0,07531297 ! stem cell division GO:0017145 11 5 0,000 0,01943863 0,07519189 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01943863 0,07507119 ! organ regeneration GO:0031100 7 5 0,000 0,01943863 0,07495089 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01943863 0,07483097 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01943863 0,07471143 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01943863 0,07459227 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,01974533 0,07564851 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,0204249 0,07812767 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,0204249 0,07800365 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,0204249 0,07788003 ! muscle fiber development GO:0048747 112 57 1,000 0,02111415 0,08038077 ! lipid modification GO:0030258 97 57 1,000 0,02111415 0,08025379 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,02252138 0,08546756 ! DNA catabolic process GO:0006308 86 59 1,000 0,02252138 0,08533296 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02323918 0,08791425 ! regulation of heart contraction GO:0008016 110 60 1,000 0,02323918 0,08777624 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02323918 0,08763866 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02328116 0,08765959 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02328116 0,08752262 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02328116 0,08738608 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02328116 0,08724997 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02328116 0,08711428 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02328116 0,08697901 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02328116 0,08684415 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02328116 0,08670972 ! sleep GO:0030431 13 6 0,000 0,02328116 0,0865757 ! response to oxygen radical GO:0000305 11 6 0,000 0,02328116 0,0864421 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02328116 0,08630891 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02328116 0,08617612 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02328116 0,08604375 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02328116 0,08591178 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02328116 0,08578021 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02328116 0,08564905 ! forebrain regionalization GO:0021871 8 6 0,000 0,02328116 0,08551829 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02328116 0,08538793 ! male meiosis GO:0007140 7 6 0,000 0,02328116 0,08525796 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02328116 0,08512839 ! response to zinc ion GO:0010043 9 6 0,000 0,02328116 0,08499921 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02328116 0,08487042 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02328116 0,08474203 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02328116 0,08461402 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02328116 0,08448639 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02328116 0,08435916 ! malate metabolic process GO:0006108 11 6 0,000 0,02328116 0,0842323 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02328116 0,08410583 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02328116 0,08397973 ! protein refolding GO:0042026 15 6 0,000 0,02328116 0,08385401 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02328116 0,08372867 ! opsonization GO:0008228 8 6 0,000 0,02328116 0,0836037 ! mating behavior GO:0007617 7 6 0,000 0,02328116 0,08347911 ! neuron remodeling GO:0016322 15 6 0,000 0,02328116 0,08335488 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02328116 0,08323102 ! equilibrioception GO:0050957 14 6 0,000 0,02328116 0,08310754 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02328116 0,08298441 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02328116 0,08286166 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02328116 0,08273926 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02328116 0,08261723 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02328116 0,08249555 ! toxin metabolic process GO:0009404 11 6 0,000 0,02328116 0,08237423 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02328116 0,08225327 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02328116 0,08213267 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02328116 0,08201242 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02328116 0,08189251 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02328116 0,08177296 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02328116 0,08165376 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02328116 0,0815349 ! thymic T cell selection GO:0045061 12 6 0,000 0,02328116 0,08141639 ! protein lipoylation GO:0009249 10 6 0,000 0,02328116 0,08129823 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02328116 0,08118041 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02328116 0,08106292 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02328116 0,08094578 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02328116 0,08082897 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02328116 0,08071251 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02328116 0,08059637 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02328116 0,08048057 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02328116 0,08036511 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02328116 0,08024997 ! hyperosmotic response GO:0006972 9 6 0,000 0,02328116 0,08013516 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02328116 0,08002069 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02328116 0,07990653 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02328116 0,07979271 ! urea metabolic process GO:0019627 7 6 0,000 0,02328116 0,0796792 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02328116 0,07956602 ! neutrophil activation GO:0042119 8 6 0,000 0,02328116 0,07945316 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02328116 0,07934062 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02328116 0,0792284 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02328116 0,0791165 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02328116 0,07900491 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02328116 0,07889363 ! neuron apoptosis GO:0051402 9 6 0,000 0,02328116 0,07878267 ! nucleoside salvage GO:0043174 9 6 0,000 0,02328116 0,07867202 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02328116 0,07856168 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02328116 0,07845165 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02328116 0,07834193 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02328116 0,07823251 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02328116 0,0781234 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02328116 0,0780146 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02328116 0,07790609 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02328116 0,07779789 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02328116 0,07768999 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02328116 0,07758238 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02328116 0,07747508 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02328116 0,07736807 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02328116 0,07726135 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02328116 0,07715493 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02328116 0,0770488 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02328116 0,07694297 ! neural nucleus development GO:0048857 14 6 0,000 0,02328116 0,07683742 ! response to UV-C GO:0010225 11 6 0,000 0,02328116 0,07673216 ! astrocyte development GO:0014002 15 6 0,000 0,02328116 0,0766272 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02328116 0,07652251 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02328116 0,07641812 ! interaction with symbiont GO:0051702 13 6 0,000 0,02328116 0,076314 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02328116 0,07621018 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02328116 0,07610663 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02328116 0,07600336 ! response to copper ion GO:0046688 10 6 0,000 0,02328116 0,07590038 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02328116 0,07579767 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02328116 0,07569524 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02328116 0,07559309 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02328116 0,07549121 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02328116 0,07538961 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02328116 0,07528828 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02328116 0,07518722 ! hair follicle maturation GO:0048820 7 6 0,000 0,02328116 0,07508643 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02328116 0,07498592 ! Schwann cell development GO:0014044 15 6 0,000 0,02328116 0,07488567 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02328116 0,07478569 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02328116 0,07468597 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02328116 0,07458652 ! subpallium development GO:0021544 10 6 0,000 0,02328116 0,07448734 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02328116 0,07438842 ! histone ubiquitination GO:0016574 8 6 0,000 0,02328116 0,07428976 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02328116 0,07419136 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02328116 0,07409323 ! G2 phase GO:0051319 16 6 0,000 0,02328116 0,07399535 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02328116 0,07389773 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02328116 0,07380037 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02328116 0,07370326 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02328116 0,07360641 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02328116 0,07350982 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02328116 0,07341347 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02328116 0,07331738 ! receptor internalization GO:0031623 10 6 0,000 0,02328116 0,07322154 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02328116 0,07312595 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02328116 0,07303061 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02328116 0,07293552 ! protein deubiquitination GO:0016579 14 6 0,000 0,02328116 0,07284068 ! protein destabilization GO:0031648 9 6 0,000 0,02328116 0,07274608 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02328116 0,07265172 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02328116 0,07255762 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02328116 0,07246375 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02328116 0,07237013 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02328116 0,07227675 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02328116 0,07218361 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02328116 0,07209071 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02328116 0,07199805 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02328116 0,07190562 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02328116 0,07181344 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02328116 0,07172148 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02328116 0,07162977 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02328116 0,07153829 ! catecholamine transport GO:0051937 9 6 0,000 0,02328116 0,07144704 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02328116 0,07135602 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02328116 0,07126524 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02328116 0,07117469 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02328116 0,07108437 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02328116 0,07099427 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02328116 0,0709044 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02328116 0,07081477 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02328116 0,07072535 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02328116 0,07063617 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02328116 0,0705472 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02328116 0,07045846 ! regulation of mitosis GO:0007088 105 63 1,000 0,02544835 0,07692052 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 1,000 0,02544835 0,07682401 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,02544835 0,07672774 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,02620305 0,07890432 GO:0048609|reproductive process in a multicellular organism, ! tRNA transcription GO:0009304 14 7 0,000 0,02710876 0,0815296 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02710876 0,08142782 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02710876 0,08132629 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02710876 0,08122501 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02710876 0,08112398 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02710876 0,08102321 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02710876 0,08092268 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02710876 0,08082241 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02710876 0,08072238 ! prostate gland development GO:0030850 13 7 0,000 0,02710876 0,0806226 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02710876 0,08052306 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02710876 0,08042378 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02710876 0,08032473 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02710876 0,08022593 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02710876 0,08012737 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02710876 0,08002906 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02710876 0,07993098 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02710876 0,07983315 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02710876 0,07973555 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02710876 0,0796382 ! glycolipid transport GO:0046836 10 7 0,000 0,02710876 0,07954108 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02710876 0,07944419 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,02710876 0,07934754 ! neuron adhesion GO:0007158 12 7 0,000 0,02710876 0,07925113 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02710876 0,07915495 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02710876 0,07905901 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02710876 0,0789633 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02710876 0,07886781 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02710876 0,07877256 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02710876 0,07867754 ! pericardium development GO:0060039 14 7 0,000 0,02710876 0,07858275 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02710876 0,07848819 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02710876 0,07839385 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02710876 0,07829974 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02710876 0,07820585 ! lipoprotein transport GO:0042953 14 7 0,000 0,02710876 0,07811219 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02710876 0,07801876 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02710876 0,07792555 ! rhythmic behavior GO:0007622 15 7 0,000 0,02710876 0,07783256 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02710876 0,07773979 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02710876 0,07764724 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02710876 0,07755491 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02710876 0,07746281 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02710876 0,07737092 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02710876 0,07727924 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02710876 0,07718779 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02710876 0,07709655 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02710876 0,07700553 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02710876 0,07691472 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02710876 0,07682412 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02710876 0,07673374 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02710876 0,07664357 ! spinal cord patterning GO:0021511 13 7 0,000 0,02710876 0,07655362 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02710876 0,07646387 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02710876 0,07637433 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02710876 0,07628501 ! adrenal gland development GO:0030325 17 7 0,000 0,02710876 0,07619589 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02710876 0,07610698 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02710876 0,07601828 ! ovulation GO:0030728 9 7 0,000 0,02710876 0,07592978 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02710876 0,07584149 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02710876 0,07575341 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02710876 0,07566552 ! microtubule nucleation GO:0007020 20 7 0,000 0,02710876 0,07557785 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02710876 0,07549037 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02710876 0,0754031 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02710876 0,07531603 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02710876 0,07522916 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02710876 0,07514249 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02710876 0,07505602 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02710876 0,07496975 ! galactose metabolic process GO:0006012 13 7 0,000 0,02710876 0,07488368 ! vesicle fusion GO:0006906 17 7 0,000 0,02710876 0,0747978 ! response to dietary excess GO:0002021 8 7 0,000 0,02710876 0,07471212 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02710876 0,07462664 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02710876 0,07454135 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02710876 0,07445626 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02710876 0,07437136 ! organ growth GO:0035265 15 7 0,000 0,02710876 0,07428665 ! purine salvage GO:0043101 10 7 0,000 0,02710876 0,07420214 ! nucleoside transport GO:0015858 8 7 0,000 0,02710876 0,07411782 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02710876 0,07403369 ! parturition GO:0007567 14 7 0,000 0,02710876 0,07394975 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02710876 0,073866 ! rRNA modification GO:0000154 14 7 0,000 0,02710876 0,07378245 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02710876 0,07369908 ! spindle checkpoint GO:0031577 15 7 0,000 0,02710876 0,07361589 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02710876 0,0735329 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02710876 0,07345009 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02710876 0,07336747 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02710876 0,07328504 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02710876 0,07320279 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02710876 0,07312072 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02710876 0,07303884 ! fibrinolysis GO:0042730 10 7 0,000 0,02710876 0,07295714 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02710876 0,07287562 ! eating behavior GO:0042755 7 7 0,000 0,02710876 0,07279429 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02710876 0,07271313 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02710876 0,07263216 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02710876 0,07255137 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02710876 0,07247076 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02710876 0,07239032 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02710876 0,07231007 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02710876 0,07222999 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02710876 0,07215009 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02710876 0,07207037 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02710876 0,07199082 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02710876 0,07191145 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02710876 0,07183225 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02710876 0,07175323 ! regulation of meiosis GO:0040020 12 7 0,000 0,02710876 0,07167438 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02710876 0,0715957 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02710876 0,0715172 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02710876 0,07143886 ! transcription termination GO:0006353 13 7 0,000 0,02710876 0,0713607 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02710876 0,07128271 ! anaphase GO:0051322 17 7 0,000 0,02710876 0,07120489 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02710876 0,07112724 ! axonal fasciculation GO:0007413 18 7 0,000 0,02710876 0,07104976 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02710876 0,07097245 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02710876 0,07089531 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02710876 0,07081833 ! diuresis GO:0030146 12 7 0,000 0,02710876 0,07074152 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02710876 0,07066488 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02710876 0,0705884 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02710876 0,07051209 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02710876 0,07043594 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02710876 0,07035996 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02710876 0,07028414 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02710876 0,07020848 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02710876 0,07013299 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02710876 0,07005766 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02710876 0,06998249 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02710876 0,06990748 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02710876 0,06983264 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02710876 0,06975795 ! lymph node development GO:0048535 10 7 0,000 0,02710876 0,06968342 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02710876 0,06960905 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02710876 0,06953484 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02710876 0,06946079 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02710876 0,0693869 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02710876 0,06931316 ! adult feeding behavior GO:0008343 9 7 0,000 0,02710876 0,06923958 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02710876 0,06916615 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02710876 0,06909288 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02710876 0,06901977 ! muscle adaptation GO:0043500 14 7 0,000 0,02710876 0,06894681 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02710876 0,068874 ! retina homeostasis GO:0001895 12 7 0,000 0,02710876 0,06880135 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02710876 0,06872885 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02710876 0,06865651 ! protein prenylation GO:0018342 18 7 0,000 0,02710876 0,06858431 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02710876 0,06851227 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02710876 0,06844038 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02710876 0,06836864 ! chromosome segregation GO:0007059 113 67 1,000 0,02852096 0,0718549 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,02852096 0,07177974 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,02852096 0,07170474 ! adaptive immune response GO:0002250 119 67 1,000 0,02852096 0,07162989 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,02931126 0,07353795 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03092149 0,07749698 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03092149 0,07741634 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03092149 0,07733586 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03092149 0,07725556 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03092149 0,07717541 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03092149 0,07709544 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03092149 0,07701563 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03092149 0,07693599 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03092149 0,07685651 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03092149 0,07677719 ! meiotic prophase I GO:0007128 13 8 0,000 0,03092149 0,07669804 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03092149 0,07661905 ! oligopeptide transport GO:0006857 15 8 0,000 0,03092149 0,07654023 ! UTP metabolic process GO:0046051 8 8 0,000 0,03092149 0,07646156 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03092149 0,07638306 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03092149 0,07630472 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03092149 0,07622654 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03092149 0,07614852 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03092149 0,07607065 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03092149 0,07599295 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03092149 0,07591541 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03092149 0,07583802 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03092149 0,07576079 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03092149 0,07568372 ! reflex GO:0060004 16 8 0,000 0,03092149 0,07560681 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03092149 0,07553005 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03092149 0,07545345 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03092149 0,075377 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03092149 0,07530071 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03092149 0,07522457 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03092149 0,07514859 ! pigment granule organization GO:0048753 16 8 0,000 0,03092149 0,07507275 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03092149 0,07499708 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03092149 0,07492155 ! histidine metabolic process GO:0006547 16 8 0,000 0,03092149 0,07484618 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03092149 0,07477095 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03092149 0,07469588 ! glycine catabolic process GO:0006546 13 8 0,000 0,03092149 0,07462096 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03092149 0,07454619 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03092149 0,07447157 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03092149 0,0743971 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03092149 0,07432278 ! melanin metabolic process GO:0006582 15 8 0,000 0,03092149 0,0742486 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03092149 0,07417458 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03092149 0,0741007 ! macrophage activation GO:0042116 12 8 0,000 0,03092149 0,07402696 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03092149 0,07395338 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03092149 0,07387994 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03092149 0,07380665 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03092149 0,0737335 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03092149 0,07366049 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03092149 0,07358764 ! osteoblast development GO:0002076 16 8 0,000 0,03092149 0,07351492 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03092149 0,07344235 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03092149 0,07336992 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03092149 0,07329764 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03092149 0,07322549 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03092149 0,07315349 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03092149 0,07308163 ! response to UV-B GO:0010224 16 8 0,000 0,03092149 0,07300991 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03092149 0,07293833 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03092149 0,07286689 ! intermediate filament organization GO:0045109 12 8 0,000 0,03092149 0,0727956 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03092149 0,07272444 ! cellular extravasation GO:0045123 12 8 0,000 0,03092149 0,07265342 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03092149 0,07258254 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03092149 0,07251179 ! response to antibiotic GO:0046677 11 8 0,000 0,03092149 0,07244119 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03092149 0,07237072 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03092149 0,07230039 ! DNA topological change GO:0006265 12 8 0,000 0,03092149 0,07223019 ! response to tropane GO:0014073 15 8 0,000 0,03092149 0,07216014 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03092149 0,07209021 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03092149 0,07202043 ! melanosome transport GO:0032402 13 8 0,000 0,03092149 0,07195077 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03092149 0,07188126 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03092149 0,07181187 ! mast cell activation GO:0045576 14 8 0,000 0,03092149 0,07174262 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03092149 0,07167351 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03092149 0,07160452 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03092149 0,07153567 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03092149 0,07146695 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03092149 0,07139837 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03092149 0,07132991 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03092149 0,07126159 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03092149 0,0711934 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03092149 0,07112533 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03092149 0,0710574 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03092149 0,0709896 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03092149 0,07092193 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03092149 0,07085438 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03092149 0,07078696 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03092149 0,07071968 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03092149 0,07065252 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03092149 0,07058548 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03092149 0,07051858 ! hormone catabolic process GO:0042447 17 8 0,000 0,03092149 0,0704518 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03092149 0,07038515 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03092149 0,07031862 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03092149 0,07025222 ! ATP catabolic process GO:0006200 11 8 0,000 0,03092149 0,07018594 ! blastocyst growth GO:0001832 19 8 0,000 0,03092149 0,07011979 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03092149 0,07005377 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03092149 0,06998786 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03092149 0,06992209 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03092149 0,06985643 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03092149 0,0697909 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03092149 0,06972549 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03092149 0,06966021 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03092149 0,06959504 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03092149 0,06953 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03092149 0,06946508 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03092149 0,06940028 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03092149 0,0693356 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03092149 0,06927104 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03092149 0,0692066 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03092149 0,06914229 ! B cell activation GO:0042113 160 71 1,000 0,03173404 0,07089332 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03255867 0,07266804 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03423299 0,07633418 GO:0090046|regulation of transcription regulator activity, ! axon extension GO:0048675 15 9 0,000 0,0347194 0,0773471 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0347194 0,07727555 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0347194 0,07720413 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0347194 0,07713284 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0347194 0,07706169 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0347194 0,07699066 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0347194 0,07691977 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0347194 0,07684901 ! phosphate transport GO:0006817 19 9 0,000 0,0347194 0,07677837 ! reproductive behavior GO:0019098 19 9 0,000 0,0347194 0,07670787 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0347194 0,0766375 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0347194 0,07656725 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0347194 0,07649713 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0347194 0,07642715 ! GTP metabolic process GO:0046039 9 9 0,000 0,0347194 0,07635729 ! RNA methylation GO:0001510 15 9 0,000 0,0347194 0,07628755 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0347194 0,07621795 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0347194 0,07614847 ! artery development GO:0060840 24 9 0,000 0,0347194 0,07607912 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0347194 0,07600989 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0347194 0,07594079 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0347194 0,07587182 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0347194 0,07580297 ! chemosensory behavior GO:0007635 20 9 0,000 0,0347194 0,07573424 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0347194 0,07566564 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0347194 0,07559717 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0347194 0,07552882 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0347194 0,07546059 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0347194 0,07539248 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0347194 0,0753245 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0347194 0,07525664 ! protein targeting to ER GO:0045047 22 9 0,000 0,0347194 0,0751889 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0347194 0,07512129 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,0347194 0,07505379 ! T cell selection GO:0045058 23 9 0,000 0,0347194 0,07498642 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0347194 0,07491917 ! endosome organization GO:0007032 17 9 0,000 0,0347194 0,07485203 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0347194 0,07478502 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0347194 0,07471813 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0347194 0,07465136 ! mannose metabolic process GO:0006013 13 9 0,000 0,0347194 0,07458471 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0347194 0,07451817 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0347194 0,07445176 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0347194 0,07438546 ! receptor clustering GO:0043113 18 9 0,000 0,0347194 0,07431928 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0347194 0,07425322 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0347194 0,07418727 ! ruffle organization GO:0031529 15 9 0,000 0,0347194 0,07412145 ! retinol metabolic process GO:0042572 18 9 0,000 0,0347194 0,07405574 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0347194 0,07399014 ! behavioral fear response GO:0001662 22 9 0,000 0,0347194 0,07392466 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0347194 0,0738593 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0347194 0,07379406 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0347194 0,07372892 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,0347194 0,07366391 ! oligodendrocyte development GO:0014003 10 9 0,000 0,0347194 0,073599 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0347194 0,07353422 ! segment specification GO:0007379 13 9 0,000 0,0347194 0,07346954 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0347194 0,07340498 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0347194 0,07334054 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0347194 0,0732762 ! response to amine stimulus GO:0014075 13 9 0,000 0,0347194 0,07321198 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0347194 0,07314787 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0347194 0,07308388 ! erythrocyte development GO:0048821 15 9 0,000 0,0347194 0,07301999 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0347194 0,07295622 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0347194 0,07289256 ! renal water homeostasis GO:0003091 14 9 0,000 0,0347194 0,07282901 ! postreplication repair GO:0006301 22 9 0,000 0,0347194 0,07276557 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0347194 0,07270224 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0347194 0,07263902 ! icosanoid secretion GO:0032309 15 9 0,000 0,0347194 0,07257591 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,0347194 0,07251291 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0347194 0,07245002 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0347194 0,07238724 ! regulation of cell division GO:0051302 15 9 0,000 0,0347194 0,07232456 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0347194 0,072262 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0347194 0,07219954 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0347194 0,07213719 ! sterol catabolic process GO:0016127 11 9 0,000 0,0347194 0,07207495 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0347194 0,07201282 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0347194 0,07195079 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0347194 0,07188887 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,0347194 0,07182706 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0347194 0,07176535 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0347194 0,07170375 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0347194 0,07164226 ! purine base metabolic process GO:0006144 21 9 0,000 0,0347194 0,07158087 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0347194 0,07151958 ! pigment granule transport GO:0051904 17 9 0,000 0,0347194 0,0714584 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0347194 0,07139733 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0347194 0,07133635 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0347194 0,07127549 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0347194 0,07121472 ! mitochondrion localization GO:0051646 15 9 0,000 0,0347194 0,07115406 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,03508254 0,07183711 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,03680604 0,07530215 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,03767983 0,07702436 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,03767983 0,07695897 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03850255 0,07857263 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03850255 0,07850604 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03850255 0,07843957 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03850255 0,07837321 ! synapsis GO:0007129 13 10 0,000 0,03850255 0,07830696 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03850255 0,07824082 ! N-glycan processing GO:0006491 20 10 0,000 0,03850255 0,07817479 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03850255 0,07810888 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03850255 0,07804308 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03850255 0,07797738 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03850255 0,0779118 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03850255 0,07784633 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,03850255 0,07778097 ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03850255 0,07771571 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03850255 0,07765057 ! androgen metabolic process GO:0008209 17 10 0,000 0,03850255 0,07758554 ! phospholipid efflux GO:0033700 16 10 0,000 0,03850255 0,07752061 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03850255 0,0774558 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03850255 0,07739109 ! pathogenesis GO:0009405 13 10 0,000 0,03850255 0,07732649 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03850255 0,07726199 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03850255 0,07719761 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03850255 0,07713333 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03850255 0,07706916 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03850255 0,0770051 ! endoderm development GO:0007492 16 10 0,000 0,03850255 0,07694114 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03850255 0,07687729 ! arginine catabolic process GO:0006527 13 10 0,000 0,03850255 0,07681354 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03850255 0,0767499 ! proline metabolic process GO:0006560 13 10 0,000 0,03850255 0,07668637 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03850255 0,07662294 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03850255 0,07655961 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03850255 0,07649639 ! V(D)J recombination GO:0033151 28 10 0,000 0,03850255 0,07643328 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03850255 0,07637027 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03850255 0,07630736 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03850255 0,07624455 ! B cell proliferation GO:0042100 18 10 0,000 0,03850255 0,07618185 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03850255 0,07611925 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03850255 0,07605676 ! multicellular organism growth GO:0035264 18 10 0,000 0,03850255 0,07599437 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03850255 0,07593208 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03850255 0,07586989 ! epithelial cell development GO:0002064 20 10 0,000 0,03850255 0,0758078 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03850255 0,07574582 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03850255 0,07568393 ! macroautophagy GO:0016236 17 10 0,000 0,03850255 0,07562215 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03850255 0,07556047 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03850255 0,07549888 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03850255 0,0754374 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03850255 0,07537602 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03850255 0,07531474 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03850255 0,07525356 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03850255 0,07519248 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03850255 0,07513149 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03850255 0,07507061 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03850255 0,07500982 ! response to dsRNA GO:0043331 20 10 0,000 0,03850255 0,07494914 ! DNA ligation GO:0006266 19 10 0,000 0,03850255 0,07488855 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03850255 0,07482805 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03850255 0,07476766 ! melanosome localization GO:0032400 16 10 0,000 0,03850255 0,07470736 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03850255 0,07464717 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03850255 0,07458706 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03850255 0,07452706 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03850255 0,07446715 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03850255 0,07440733 ! mRNA cleavage GO:0006379 17 10 0,000 0,03850255 0,07434762 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03850255 0,074288 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03850255 0,07422847 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03850255 0,07416904 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03850255 0,07410971 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03850255 0,07405047 ! salivary gland development GO:0007431 27 10 0,000 0,03850255 0,07399132 ! prophase GO:0051324 15 10 0,000 0,03850255 0,07393227 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03850255 0,07387331 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03850255 0,07381445 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03850255 0,07375568 ! midbrain development GO:0030901 13 10 0,000 0,03850255 0,073697 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03850255 0,07363842 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03850255 0,07357993 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03850255 0,07352153 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03850255 0,07346323 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03850255 0,07340502 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03850255 0,0733469 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03850255 0,07328887 ! detection of calcium ion GO:0005513 23 10 0,000 0,03850255 0,07323093 ! oocyte development GO:0048599 17 10 0,000 0,03850255 0,07317309 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03850255 0,07311534 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03850255 0,07305767 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03850255 0,0730001 ! activation of innate immune response GO:0002218 12 10 0,000 0,03850255 0,07294262 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03850255 0,07288523 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03850255 0,07282793 ! response to nicotine GO:0035094 20 10 0,000 0,03850255 0,07277072 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03850255 0,0727136 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03850255 0,07265657 ! localization within membrane GO:0051668 20 10 0,000 0,03850255 0,07259963 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,03856155 0,07265394 ! response to metal ion GO:0010038 140 80 1,000 0,03945113 0,07427184 ! T cell activation GO:0042110 168 81 1,000 0,04034848 0,07590184 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,04034848 0,07584254 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,042271 0,07939424 ! respiratory burst GO:0045730 17 11 0,000 0,042271 0,07933231 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,042271 0,07927048 ! neuron fate specification GO:0048665 17 11 0,000 0,042271 0,07920874 ! telencephalon cell migration GO:0022029 20 11 0,000 0,042271 0,0791471 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,042271 0,07908555 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,042271 0,0790241 ! thyroid gland development GO:0030878 26 11 0,000 0,042271 0,07896275 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,042271 0,07890149 ! response to pain GO:0048265 24 11 0,000 0,042271 0,07884033 ! T cell proliferation GO:0042098 26 11 0,000 0,042271 0,07877926 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,042271 0,07871828 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,042271 0,0786574 ! ventral spinal cord development GO:0021517 21 11 0,000 0,042271 0,07859662 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,042271 0,07853592 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,042271 0,07847532 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,042271 0,07841482 ! melanocyte differentiation GO:0030318 21 11 0,000 0,042271 0,07835441 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,042271 0,07829409 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,042271 0,07823386 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,042271 0,07817373 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,042271 0,07811369 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,042271 0,07805374 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,042271 0,07799388 ! UV protection GO:0009650 19 11 0,000 0,042271 0,07793412 ! adult heart development GO:0007512 14 11 0,000 0,042271 0,07787444 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,042271 0,07781486 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,042271 0,07775537 ! temperature homeostasis GO:0001659 17 11 0,000 0,042271 0,07769597 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,042271 0,07763666 ! negative regulation of ossification GO:0030279 26 11 0,000 0,042271 0,07757744 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,042271 0,07751831 ! regulation of organ growth GO:0046620 13 11 0,000 0,042271 0,07745927 ! pigment granule localization GO:0051875 20 11 0,000 0,042271 0,07740032 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,042271 0,07734146 ! vasoconstriction GO:0042310 18 11 0,000 0,042271 0,07728269 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,042271 0,07722401 ! embryonic axis specification GO:0000578 18 11 0,000 0,042271 0,07716542 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,042271 0,07710691 ! snRNA metabolic process GO:0016073 24 11 0,000 0,042271 0,0770485 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,042271 0,07699017 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,042271 0,07693194 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,042271 0,07687379 ! zymogen activation GO:0031638 15 11 0,000 0,042271 0,07681573 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,042271 0,07675775 ! neuroblast proliferation GO:0007405 24 11 0,000 0,042271 0,07669986 ! nucleosome positioning GO:0016584 15 11 0,000 0,042271 0,07664207 ! regulation of isotype switching GO:0045191 22 11 0,000 0,042271 0,07658435 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,042271 0,07652673 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,042271 0,07646919 ! acid secretion GO:0046717 18 11 0,000 0,042271 0,07641174 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,042271 0,07635437 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,042271 0,07629709 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,042271 0,0762399 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,042271 0,07618279 ! oocyte differentiation GO:0009994 18 11 0,000 0,042271 0,07612576 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,042271 0,07606883 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,042271 0,07601197 ! cholesterol efflux GO:0033344 19 11 0,000 0,042271 0,07595521 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,042271 0,07589852 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,042271 0,07584192 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,042271 0,07578541 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,042271 0,07572898 ! embryonic gut development GO:0048566 15 11 0,000 0,042271 0,07567263 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,042271 0,07561637 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,042271 0,07556019 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,042271 0,0755041 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,042271 0,07544809 ! defense response to fungus GO:0050832 13 11 0,000 0,042271 0,07539216 ! developmental induction GO:0031128 19 11 0,000 0,042271 0,07533631 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,042271 0,07528055 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,042271 0,07522487 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,042271 0,07516927 ! sequestering of metal ion GO:0051238 14 11 0,000 0,042271 0,07511375 ! lamellipodium assembly GO:0030032 20 11 0,000 0,042271 0,07505832 ! regulation of synapse organization GO:0050807 17 11 0,000 0,042271 0,07500296 ! response to unfolded protein GO:0006986 131 85 1,000 0,04401427 0,07803856 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,04401427 0,07798109 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,04401427 0,07792371 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,04494944 0,07952085 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,0460248 0,08136346 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,0460248 0,08130372 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,0460248 0,08124407 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,0460248 0,08118451 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,0460248 0,08112504 ! cartilage condensation GO:0001502 20 12 0,000 0,0460248 0,08106565 ! mating GO:0007618 17 12 0,000 0,0460248 0,08100634 ! protein complex disassembly GO:0043241 27 12 0,000 0,0460248 0,08094713 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,0460248 0,080888 ! hippocampus development GO:0021766 26 12 0,000 0,0460248 0,08082896 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,0460248 0,08077 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,0460248 0,08071113 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,0460248 0,08065235 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,0460248 0,08059365 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,0460248 0,08053503 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,0460248 0,08047651 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,0460248 0,08041806 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,0460248 0,0803597 ! drug transport GO:0015893 16 12 0,000 0,0460248 0,08030143 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,0460248 0,08024324 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,0460248 0,08018514 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,0460248 0,08012711 ! polyamine metabolic process GO:0006595 17 12 0,000 0,0460248 0,08006918 ! focal adhesion formation GO:0048041 35 12 0,000 0,0460248 0,08001132 ! mitotic spindle organization GO:0007052 21 12 0,000 0,0460248 0,07995355 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,0460248 0,07989587 ! forebrain cell migration GO:0021885 21 12 0,000 0,0460248 0,07983826 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,0460248 0,07978074 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,0460248 0,07972331 ! fear response GO:0042596 26 12 0,000 0,0460248 0,07966595 ! monoamine transport GO:0015844 18 12 0,000 0,0460248 0,07960868 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,0460248 0,07955149 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,0460248 0,07949438 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,0460248 0,07943736 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,0460248 0,07938041 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,0460248 0,07932355 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,0460248 0,07926677 ! protein homotetramerization GO:0051289 21 12 0,000 0,0460248 0,07921007 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,0460248 0,07915345 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,0460248 0,07909691 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,0460248 0,07904045 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,0460248 0,07898407 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,0460248 0,07892778 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,0460248 0,07887156 ! cranial nerve development GO:0021545 20 12 0,000 0,0460248 0,07881543 ! fucose catabolic process GO:0019317 22 12 0,000 0,0460248 0,07875937 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,0460248 0,07870339 ! histone methylation GO:0016571 26 12 0,000 0,0460248 0,07864749 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,0460248 0,07859168 ! autonomic nervous system development GO:0048483 24 12 0,000 0,0460248 0,07853594 ! gland morphogenesis GO:0022612 29 12 0,000 0,0460248 0,07848028 ! T cell homeostasis GO:0043029 25 12 0,000 0,0460248 0,0784247 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,0460248 0,0783692 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,0460248 0,07831377 ! spleen development GO:0048536 22 12 0,000 0,0460248 0,07825843 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,0460248 0,07820316 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,0460248 0,07814797 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,0460248 0,07809286 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,0460248 0,07803782 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,0460248 0,07798287 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,0460248 0,07792799 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,0460248 0,07787319 ! response to cold GO:0009409 17 12 0,000 0,0460248 0,07781846 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,0460248 0,07776382 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,0460248 0,07770924 ! regulation of DNA binding GO:0051101 155 88 1,000 0,04684175 0,07903314 ! gland development GO:0048732 206 88 1,000 0,04684175 0,07897776 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,04779876 0,08053488 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,04876289 0,08210184 ! response to protein stimulus GO:0051789 149 91 1,000 0,0497341 0,08367849 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04976402 0,08367032 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,04976402 0,08361189 ! peroxisomal transport GO:0043574 24 13 0,000 0,04976402 0,08355354 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,04976402 0,08349528 ! lipid localization GO:0010876 28 13 0,000 0,04976402 0,08343709 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,04976402 0,08337899 ! organelle fusion GO:0048284 32 13 0,000 0,04976402 0,08332096 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,04976402 0,08326302 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,04976402 0,08320516 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,04976402 0,08314738 ! endocrine pancreas development GO:0031018 22 13 0,000 0,04976402 0,08308968 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,04976402 0,08303206 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,04976402 0,08297451 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,04976402 0,08291705 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,04976402 0,08285967 ! methionine metabolic process GO:0006555 27 13 0,000 0,04976402 0,08280237 ! plasma membrane organization GO:0007009 24 13 0,000 0,04976402 0,08274514 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,04976402 0,082688 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,04976402 0,08263093 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,04976402 0,08257395 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,04976402 0,08251704 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,04976402 0,08246021 ! cytokine metabolic process GO:0042107 22 13 0,000 0,04976402 0,08240346 ! exocrine system development GO:0035272 32 13 0,000 0,04976402 0,08234678 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,04976402 0,08229019 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,04976402 0,08223367 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,04976402 0,08217723 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,04976402 0,08212087 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,04976402 0,08206458 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,04976402 0,08200837 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,04976402 0,08195224 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,04976402 0,08189619 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,04976402 0,08184021 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04976402 0,08178431 ! ribosome assembly GO:0042255 17 13 0,000 0,04976402 0,08172848 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,04976402 0,08167273 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,04976402 0,08161706 ! chromatin silencing GO:0006342 26 13 0,000 0,04976402 0,08156146 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,04976402 0,08150594 ! regulation of epidermis development GO:0045682 19 13 0,000 0,04976402 0,08145049 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04976402 0,08139512 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,04976402 0,08133983 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,04976402 0,08128461 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04976402 0,08122946 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,04976402 0,08117439 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,04976402 0,08111939 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,04976402 0,08106447 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,04976402 0,08100962 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,04976402 0,08095485 ! insulin secretion GO:0030073 23 13 0,000 0,04976402 0,08090015 ! actin filament polymerization GO:0030041 24 13 0,000 0,04976402 0,08084553 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,04976402 0,08079097 ! acrosome reaction GO:0007340 18 13 0,000 0,04976402 0,0807365 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,05169743 0,08381672 ! female pregnancy GO:0007565 164 94 1,000 0,05268942 0,08536751 ! rRNA transcription GO:0009303 25 14 0,000 0,0534887 0,08660418 ! lactation GO:0007595 26 14 0,000 0,0534887 0,08654594 ! reproductive cellular process GO:0048610 20 14 0,000 0,0534887 0,08648778 ! tRNA modification GO:0006400 20 14 0,000 0,0534887 0,08642969 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0534887 0,08637169 ! regulation of S phase GO:0033261 23 14 0,000 0,0534887 0,08631376 ! water transport GO:0006833 21 14 0,000 0,0534887 0,08625591 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0534887 0,08619813 ! non-recombinational repair GO:0000726 25 14 0,000 0,0534887 0,08614044 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0534887 0,08608282 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0534887 0,08602527 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0534887 0,08596781 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0534887 0,08591042 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0534887 0,08585311 ! palate development GO:0060021 31 14 0,000 0,0534887 0,08579587 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0534887 0,08573871 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0534887 0,08568163 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0534887 0,08562462 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0534887 0,08556769 ! arginine metabolic process GO:0006525 17 14 0,000 0,0534887 0,08551084 ! regulation of heart rate GO:0002027 24 14 0,000 0,0534887 0,08545406 ! organic alcohol transport GO:0015850 29 14 0,000 0,0534887 0,08539735 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,0534887 0,08534072 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0534887 0,08528417 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0534887 0,08522769 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0534887 0,08517128 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0534887 0,08511495 ! L-amino acid transport GO:0015807 30 14 0,000 0,0534887 0,0850587 ! bone mineralization GO:0030282 17 14 0,000 0,0534887 0,08500252 ! stem cell development GO:0048864 43 14 0,000 0,0534887 0,08494641 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0534887 0,08489038 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0534887 0,08483442 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0534887 0,08477853 ! cerebellum development GO:0021549 21 14 0,000 0,0534887 0,08472272 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0534887 0,08466698 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0534887 0,08461132 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0534887 0,08455572 ! cofactor transport GO:0051181 26 14 0,000 0,0534887 0,0845002 ! NADP metabolic process GO:0006739 24 14 0,000 0,0534887 0,08444476 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0534887 0,08438938 ! intestinal absorption GO:0050892 25 14 0,000 0,0534887 0,08433408 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0534887 0,08427885 ! oxygen transport GO:0015671 21 14 0,000 0,0534887 0,0842237 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0534887 0,08416861 ! male genitalia development GO:0030539 24 14 0,000 0,0534887 0,0841136 ! regulation of axon extension GO:0030516 37 14 0,000 0,0534887 0,08405866 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0534887 0,08400379 ! mRNA transport GO:0051028 169 96 1,000 0,05469371 0,08584023 ! detection of stimulus GO:0051606 151 96 1,000 0,05469371 0,08578427 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05719891 0,08965509 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05719891 0,08959672 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,05719891 0,08953843 ! superoxide anion generation GO:0042554 20 15 0,000 0,05719891 0,08948021 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05719891 0,08942207 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05719891 0,089364 ! copper ion transport GO:0006825 20 15 0,000 0,05719891 0,08930601 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05719891 0,0892481 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05719891 0,08919026 ! sulfate transport GO:0008272 23 15 0,000 0,05719891 0,08913249 ! response to cAMP GO:0051591 22 15 0,000 0,05719891 0,0890748 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05719891 0,08901718 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05719891 0,08895964 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05719891 0,08890217 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05719891 0,08884478 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05719891 0,08878746 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05719891 0,08873022 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05719891 0,08867305 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,05719891 0,08861595 ! pituitary gland development GO:0021983 29 15 0,000 0,05719891 0,08855892 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,05719891 0,08850197 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05719891 0,08844509 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05719891 0,08838829 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05719891 0,08833156 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05719891 0,0882749 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,05719891 0,08821831 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05719891 0,0881618 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05719891 0,08810536 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05719891 0,08804899 ! tissue regeneration GO:0042246 26 15 0,000 0,05719891 0,08799269 ! water homeostasis GO:0030104 27 15 0,000 0,05719891 0,08793646 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05719891 0,08788031 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05719891 0,08782423 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05719891 0,08776822 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05719891 0,08771228 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05719891 0,08765641 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05719891 0,08760062 ! cell killing GO:0001906 29 15 0,000 0,05719891 0,08754489 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,05719891 0,08748924 ! detection of bacterium GO:0016045 18 15 0,000 0,05719891 0,08743365 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05719891 0,08737814 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05719891 0,08732269 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05719891 0,08726732 ! peptide hormone processing GO:0016486 23 15 0,000 0,05719891 0,08721202 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06089469 0,09278824 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06089469 0,09272951 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06089469 0,09267086 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06089469 0,09261228 ! bone remodeling GO:0046849 27 16 0,000 0,06089469 0,09255378 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06089469 0,09249534 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06089469 0,09243699 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06089469 0,09237871 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06089469 0,0923205 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06089469 0,09226236 ! startle response GO:0001964 28 16 0,000 0,06089469 0,0922043 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06089469 0,09214631 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06089469 0,09208839 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06089469 0,09203054 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06089469 0,09197277 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06089469 0,09191507 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06089469 0,09185745 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06089469 0,09179989 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06089469 0,09174241 ! response to osmotic stress GO:0006970 25 16 0,000 0,06089469 0,091685 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06089469 0,09162766 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06089469 0,09157039 ! fructose metabolic process GO:0006000 25 16 0,000 0,06089469 0,0915132 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06089469 0,09145607 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06089469 0,09139902 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06089469 0,09134204 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06089469 0,09128513 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06089469 0,09122829 ! axon cargo transport GO:0008088 43 16 0,000 0,06089469 0,09117152 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06089469 0,09111482 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06089469 0,09105819 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06089469 0,09100163 ! DNA replication initiation GO:0006270 27 16 0,000 0,06089469 0,09094514 ! neuron recognition GO:0008038 35 16 0,000 0,06089469 0,09088873 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06089469 0,09083238 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06089469 0,0907761 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06089469 0,09071989 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06089469 0,09066375 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06089469 0,09060768 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06089469 0,09055168 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06089469 0,09049575 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06089469 0,09043989 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06089469 0,0903841 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06089469 0,09032838 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06089469 0,09027272 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,06089469 0,09021713 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06457611 0,09561238 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06457611 0,09555358 ! metencephalon development GO:0022037 30 17 0,000 0,06457611 0,09549485 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06457611 0,09543619 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06457611 0,09537761 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06457611 0,09531909 ! signal complex assembly GO:0007172 41 17 0,000 0,06457611 0,09526065 ! inositol metabolic process GO:0006020 28 17 0,000 0,06457611 0,09520228 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06457611 0,09514398 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06457611 0,09508575 ! glial cell development GO:0021782 27 17 0,000 0,06457611 0,0950276 ! limbic system development GO:0021761 36 17 0,000 0,06457611 0,09496951 ! adult walking behavior GO:0007628 33 17 0,000 0,06457611 0,0949115 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06457611 0,09485355 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06457611 0,09479568 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06457611 0,09473788 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06457611 0,09468015 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06457611 0,09462249 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06457611 0,0945649 ! glycine metabolic process GO:0006544 28 17 0,000 0,06457611 0,09450737 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06457611 0,09444992 ! NAD metabolic process GO:0019674 29 17 0,000 0,06457611 0,09439254 ! DNA integration GO:0015074 29 17 0,000 0,06457611 0,09433523 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06457611 0,09427799 ! regulation of protein binding GO:0043393 33 17 0,000 0,06457611 0,09422081 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06457611 0,09416371 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06457611 0,09410668 ! genitalia development GO:0048806 30 17 0,000 0,06457611 0,09404971 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06457611 0,09399281 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06457611 0,09393599 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06457611 0,09387923 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06457611 0,09382254 ! steroid catabolic process GO:0006706 31 17 0,000 0,06457611 0,09376592 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06457611 0,09370936 ! gas transport GO:0015669 25 17 0,000 0,06457611 0,09365288 ! organic cation transport GO:0015695 31 17 0,000 0,06457611 0,09359646 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06457611 0,09354011 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06457611 0,09348383 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06457611 0,09342761 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06457611 0,09337147 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06824322 0,09861453 ! neuron maturation GO:0042551 42 18 0,000 0,06824322 0,09855534 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06824322 0,09849621 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06824322 0,09843716 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06824322 0,09837818 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06824322 0,09831928 ! memory GO:0007613 31 18 0,000 0,06824322 0,09826044 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06824322 0,09820167 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06824322 0,09814297 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06824322 0,09808434 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06824322 0,09802579 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06824322 0,0979673 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06824322 0,09790888 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,06824322 0,09785053 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06824322 0,09779225 ! response to retinoic acid GO:0032526 26 18 0,000 0,06824322 0,09773404 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,06824322 0,0976759 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,06824322 0,09761783 ! response to fungus GO:0009620 21 18 0,000 0,06824322 0,09755983 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06824322 0,09750189 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,06824322 0,09744403 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06824322 0,09738623 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06824322 0,09732851 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06824322 0,09727085 ! vitamin transport GO:0051180 27 18 0,000 0,06824322 0,09721326 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06824322 0,09715573 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06824322 0,09709828 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,06824322 0,09704089 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,06824322 0,09698357 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06824322 0,09692632 ! nerve development GO:0021675 28 18 0,000 0,06824322 0,09686914 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06824322 0,09681202 ! protein secretion GO:0009306 39 19 0,000 0,07189608 0,10193398 ! positive regulation of translation GO:0045727 30 19 0,000 0,07189608 0,10187395 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07189608 0,10181399 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,07189608 0,10175409 ! skin development GO:0043588 36 19 0,000 0,07189608 0,10169427 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07189608 0,10163452 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07189608 0,10157484 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07189608 0,10151524 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07189608 0,1014557 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07189608 0,10139623 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07189608 0,10133683 ! cerebral cortex development GO:0021987 36 19 0,000 0,07189608 0,10127749 ! pigmentation during development GO:0048066 41 19 0,000 0,07189608 0,10121823 ! response to vitamin A GO:0033189 27 19 0,000 0,07189608 0,10115904 ! heme metabolic process GO:0042168 36 19 0,000 0,07189608 0,10109992 ! actin filament bundle formation GO:0051017 42 19 0,000 0,07189608 0,10104086 ! neuromuscular junction development GO:0007528 34 19 0,000 0,07189608 0,10098188 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07189608 0,10092296 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07189608 0,10086412 ! peptide cross-linking GO:0018149 37 19 0,000 0,07189608 0,10080534 ! protein export from nucleus GO:0006611 36 19 0,000 0,07189608 0,10074663 ! heart process GO:0003015 30 19 0,000 0,07189608 0,10068799 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07189608 0,10062941 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07189608 0,10057091 ! visual learning GO:0008542 36 19 0,000 0,07189608 0,10051247 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07189608 0,1004541 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07189608 0,1003958 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07189608 0,10033756 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07189608 0,1002794 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07189608 0,1002213 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07189608 0,10016327 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07189608 0,1001053 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07189608 0,1000474 ! cilium assembly GO:0042384 37 19 0,000 0,07189608 0,09998957 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07189608 0,09993181 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07553473 0,10492873 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,07553473 0,10486819 ! positive regulation of ossification GO:0045778 47 20 0,000 0,07553473 0,10480771 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07553473 0,1047473 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,07553473 0,10468696 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07553473 0,10462669 ! response to vitamin GO:0033273 31 20 0,000 0,07553473 0,10456649 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,07553473 0,10450636 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,07553473 0,1044463 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07553473 0,10438631 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07553473 0,10432639 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,07553473 0,10426653 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07553473 0,10420675 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07553473 0,10414703 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,07553473 0,10408738 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07553473 0,1040278 ! body fluid secretion GO:0007589 31 20 0,000 0,07553473 0,10396829 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07553473 0,10390884 ! peptide secretion GO:0002790 35 20 0,000 0,07553473 0,10384947 ! stem cell differentiation GO:0048863 53 20 0,000 0,07553473 0,10379016 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07553473 0,10373092 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07553473 0,10367174 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,07553473 0,10361264 ! sensory perception of pain GO:0019233 30 20 0,000 0,07553473 0,1035536 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07553473 0,10349463 ! diencephalon development GO:0021536 34 20 0,000 0,07553473 0,10343572 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07553473 0,10337689 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,07553473 0,10331812 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,07553473 0,10325941 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,07553473 0,10320078 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07553473 0,10314221 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,07553473 0,1030837 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07553473 0,10302526 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07553473 0,10296689 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07553473 0,10290859 ! regulation of glucose import GO:0046324 29 20 0,000 0,07553473 0,10285035 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07553473 0,10279218 ! actin filament-based movement GO:0030048 43 20 0,000 0,07553473 0,10273407 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,07553473 0,10267603 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07553473 0,10261805 ! negative regulation of translation GO:0017148 29 20 0,000 0,07553473 0,10256014 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07553473 0,10250229 ! regulation of cell killing GO:0031341 42 21 0,000 0,07915924 0,10736028 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,07915924 0,1072998 ! hormone secretion GO:0046879 38 21 0,000 0,07915924 0,10723938 ! glycerol metabolic process GO:0006071 34 21 0,000 0,07915924 0,10717903 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,07915924 0,10711875 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,07915924 0,10705854 ! axis specification GO:0009798 38 21 0,000 0,07915924 0,10699839 ! ovarian follicle development GO:0001541 35 21 0,000 0,07915924 0,10693832 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,07915924 0,10687831 ! smooth muscle contraction GO:0006939 46 21 0,000 0,07915924 0,10681836 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,07915924 0,10675849 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,07915924 0,10669868 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,07915924 0,10663894 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,07915924 0,10657926 ! cytolysis GO:0019835 24 21 0,000 0,07915924 0,10651965 ! vasodilation GO:0042311 39 21 0,000 0,07915924 0,10646011 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,07915924 0,10640064 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,07915924 0,10634123 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,07915924 0,10628189 ! oogenesis GO:0048477 36 21 0,000 0,07915924 0,10622261 ! collagen fibril organization GO:0030199 59 21 0,000 0,07915924 0,1061634 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,07915924 0,10610426 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,07915924 0,10604518 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,07915924 0,10598617 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,07915924 0,10592722 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,07915924 0,10586834 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,07915924 0,10580952 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,07915924 0,10575077 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,07915924 0,10569209 ! collagen catabolic process GO:0030574 28 21 0,000 0,07915924 0,10563347 ! sperm-egg recognition GO:0035036 21 21 0,000 0,07915924 0,10557491 ! gut development GO:0048565 39 21 0,000 0,07915924 0,10551642 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08276966 0,11026789 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08276966 0,11020687 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08276966 0,11014591 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08276966 0,11008503 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08276966 0,1100242 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08276966 0,10996345 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08276966 0,10990277 ! regeneration GO:0031099 41 22 0,000 0,08276966 0,10984215 ! keratinization GO:0031424 28 22 0,000 0,08276966 0,10978159 ! sensory perception of taste GO:0050909 28 22 0,000 0,08276966 0,10972111 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08276966 0,10966069 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08276966 0,10960034 ! vacuolar transport GO:0007034 36 22 0,000 0,08276966 0,10954005 ! lysosome organization GO:0007040 41 22 0,000 0,08276966 0,10947983 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08276966 0,10941968 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08276966 0,10935959 ! fucose metabolic process GO:0006004 39 22 0,000 0,08276966 0,10929957 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08276966 0,10923961 ! ureteric bud development GO:0001657 43 22 0,000 0,08276966 0,10917972 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08276966 0,1091199 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08276966 0,10906014 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08276966 0,10900044 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,08276966 0,10894082 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08276966 0,10888125 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08276966 0,10882175 ! sarcomere organization GO:0045214 30 22 0,000 0,08276966 0,10876232 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08276966 0,10870295 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08276966 0,10864365 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08276966 0,10858441 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08276966 0,10852524 ! protein stabilization GO:0050821 39 22 0,000 0,08276966 0,10846613 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,08636605 0,11311743 ! gluconeogenesis GO:0006094 33 23 0,000 0,08636605 0,11305588 ! viral genome replication GO:0019079 41 23 0,000 0,08636605 0,11299441 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,08636605 0,112933 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,08636605 0,11287165 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,08636605 0,11281038 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,08636605 0,11274917 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,08636605 0,11268802 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,08636605 0,11262694 ! visual behavior GO:0007632 42 23 0,000 0,08636605 0,11256593 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,08636605 0,11250499 ! response to ethanol GO:0045471 46 23 0,000 0,08636605 0,11244411 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,08636605 0,11238329 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,08636605 0,11232255 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,08636605 0,11226186 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,08636605 0,11220125 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,08636605 0,1121407 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,08636605 0,11208021 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,08636605 0,11201979 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,08636605 0,11195943 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,08636605 0,11189914 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,08636605 0,11183892 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,08636605 0,11177876 ! fatty acid transport GO:0015908 44 23 0,000 0,08636605 0,11171866 ! platelet activation GO:0030168 37 23 0,000 0,08636605 0,11165863 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,08636605 0,11159866 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,08636605 0,11153876 ! hormone transport GO:0009914 40 23 0,000 0,08636605 0,11147892 ! cell-cell recognition GO:0009988 25 23 0,000 0,08636605 0,11141915 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,08636605 0,11135944 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,08636605 0,11129979 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,08636605 0,11124021 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,08636605 0,11118069 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,08636605 0,11112124 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,08994845 0,11566861 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,08994845 0,11560682 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,08994845 0,1155451 ! vesicle docking GO:0048278 47 24 0,000 0,08994845 0,11548344 ! spinal cord development GO:0021510 47 24 0,000 0,08994845 0,11542185 ! vacuole organization GO:0007033 43 24 0,000 0,08994845 0,11536033 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,08994845 0,11529887 ! digestive system process GO:0022600 39 24 0,000 0,08994845 0,11523747 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,08994845 0,11517614 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,08994845 0,11511488 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,08994845 0,11505368 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,08994845 0,11499255 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,08994845 0,11493148 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,08994845 0,11487047 ! membrane depolarization GO:0051899 39 24 0,000 0,08994845 0,11480953 ! pallium development GO:0021543 49 24 0,000 0,08994845 0,11474866 ! pentose metabolic process GO:0019321 35 24 0,000 0,08994845 0,11468785 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,08994845 0,1146271 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,08994845 0,11456642 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,08994845 0,1145058 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,08994845 0,11444525 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,08994845 0,11438476 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,08994845 0,11432434 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,08994845 0,11426398 ! regulation of amine transport GO:0051952 40 24 0,000 0,08994845 0,11420368 ! myelination GO:0042552 45 25 0,000 0,09351692 0,11867179 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09351692 0,11860923 ! phototransduction GO:0007602 33 25 0,000 0,09351692 0,11854674 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09351692 0,11848432 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,09351692 0,11842196 ! receptor metabolic process GO:0043112 46 25 0,000 0,09351692 0,11835966 ! chromosome condensation GO:0030261 45 25 0,000 0,09351692 0,11829743 ! osteoblast differentiation GO:0001649 60 25 0,000 0,09351692 0,11823527 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09351692 0,11817317 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,09351692 0,11811114 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09351692 0,11804917 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,09351692 0,11798727 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09351692 0,11792543 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09351692 0,11786366 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09351692 0,11780195 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09351692 0,1177403 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09351692 0,11767872 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09351692 0,11761721 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09351692 0,11755576 ! telomere organization GO:0032200 43 25 0,000 0,09351692 0,11749437 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09351692 0,11743305 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09351692 0,11737179 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09707152 0,1217696 ! embryonic pattern specification GO:0009880 44 26 0,000 0,09707152 0,12170614 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09707152 0,12164275 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09707152 0,12157943 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09707152 0,12151617 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09707152 0,12145298 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09707152 0,12138986 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09707152 0,1213268 ! molting cycle process GO:0022404 50 26 0,000 0,09707152 0,1212638 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,09707152 0,12120087 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09707152 0,12113801 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,09707152 0,12107521 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,09707152 0,12101248 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09707152 0,12094981 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09707152 0,12088721 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09707152 0,12082467 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,09707152 0,12076219 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09707152 0,12069979 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09707152 0,12063744 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09707152 0,12057516 ! leukocyte proliferation GO:0070661 52 26 0,000 0,09707152 0,12051294 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09707152 0,12045079 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09707152 0,1203887 ! neuron fate commitment GO:0048663 48 27 0,000 0,1006123 0,12471571 ! iron ion transport GO:0006826 59 27 0,000 0,1006123 0,12465149 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,1006123 0,12458734 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,1006123 0,12452325 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,1006123 0,12445923 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,1006123 0,12439527 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,1006123 0,12433138 ! autophagy GO:0006914 41 27 0,000 0,1006123 0,12426755 ! male gonad development GO:0008584 44 27 0,000 0,1006123 0,1242038 ! primary neural tube formation GO:0014020 51 27 0,000 0,1006123 0,1241401 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,1006123 0,12407647 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,1006123 0,12401291 ! glutathione metabolic process GO:0006749 39 27 0,000 0,1006123 0,12394941 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,1006123 0,12388598 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,1006123 0,12382261 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,1006123 0,1237593 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,1006123 0,12369606 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10413931 0,1279669 ! circadian rhythm GO:0007623 50 28 0,000 0,10413931 0,12790157 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10413931 0,12783632 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10413931 0,12777113 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,10413931 0,12770601 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10413931 0,12764095 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,10413931 0,12757596 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10413931 0,12751104 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10413931 0,12744618 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,10413931 0,12738139 ! synaptogenesis GO:0007416 42 28 0,000 0,10413931 0,12731666 ! lipid oxidation GO:0034440 43 28 0,000 0,10413931 0,127252 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10413931 0,1271874 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,10413931 0,12712287 ! translational initiation GO:0006413 65 29 0,000 0,10765261 0,13134492 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,10765261 0,13127834 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,10765261 0,13121184 ! catechol metabolic process GO:0009712 54 29 0,000 0,10765261 0,1311454 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,10765261 0,13107904 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,10765261 0,13101273 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,10765261 0,1309465 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,10765261 0,13088033 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,10765261 0,13081423 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,10765261 0,1307482 ! cell fate determination GO:0001709 60 29 0,000 0,10765261 0,13068223 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,10765261 0,13061633 ! detection of light stimulus GO:0009583 38 29 0,000 0,10765261 0,13055049 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,10765261 0,13048472 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,10765261 0,13041902 ! tissue homeostasis GO:0001894 48 29 0,000 0,10765261 0,13035338 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,10765261 0,13028781 ! phenol metabolic process GO:0018958 55 30 0,000 0,11115224 0,13445565 ! zinc ion transport GO:0006829 45 30 0,000 0,11115224 0,13438809 ! membrane docking GO:0022406 61 30 0,000 0,11115224 0,13432059 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,11115224 0,13425316 ! cell junction assembly GO:0034329 78 30 0,000 0,11115224 0,1341858 ! regulation of innate immune response GO:0045088 51 30 0,000 0,11115224 0,1341185 ! acute-phase response GO:0006953 49 30 0,000 0,11115224 0,13405128 ! myofibril assembly GO:0030239 47 30 0,000 0,11115224 0,13398412 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,11115224 0,13391702 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,11115224 0,13385 ! phospholipid transport GO:0015914 51 30 0,000 0,11115224 0,13378304 ! ensheathment of neurons GO:0007272 57 30 0,000 0,11115224 0,13371615 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,11115224 0,13364932 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,11115224 0,13358256 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,11115224 0,13351587 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,11115224 0,13344925 ! eye morphogenesis GO:0048592 60 30 0,000 0,11115224 0,13338269 ! response to heat GO:0009408 50 30 0,000 0,11115224 0,1333162 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11463827 0,13742883 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11463827 0,13736039 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11463827 0,13729202 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11463827 0,13722372 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11463827 0,13715548 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11463827 0,13708731 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,11463827 0,13701921 ! ovulation cycle process GO:0022602 49 31 0,000 0,11463827 0,13695118 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11463827 0,13688321 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,11463827 0,13681531 ! peptide transport GO:0015833 55 31 0,000 0,11463827 0,13674748 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,11463827 0,13667972 ! mesoderm formation GO:0001707 69 31 0,000 0,11463827 0,13661202 ! natural killer cell activation GO:0030101 45 31 0,000 0,11463827 0,13654439 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11463827 0,13647683 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11463827 0,13640933 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11463827 0,1363419 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,11463827 0,13627454 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11463827 0,13620724 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,11811074 0,14026379 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,11811074 0,14019459 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,11811074 0,14012546 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,11811074 0,1400564 ! cholesterol transport GO:0030301 56 32 0,000 0,11811074 0,1399874 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,11811074 0,13991848 ! spliceosome assembly GO:0000245 67 32 0,000 0,11811074 0,13984962 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,11811074 0,13978083 ! metanephros development GO:0001656 74 32 0,000 0,11811074 0,13971211 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,11811074 0,13964345 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,11811074 0,13957487 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,11811074 0,13950635 ! muscle cell development GO:0055001 49 32 0,000 0,11811074 0,13943789 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,11811074 0,13936951 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,11811074 0,13930119 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,11811074 0,13923294 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,11811074 0,13916475 ! ovulation cycle GO:0042698 51 32 0,000 0,11811074 0,13909664 ! peripheral nervous system development GO:0007422 64 32 0,000 0,11811074 0,13902859 ! BMP signaling pathway GO:0030509 64 32 0,000 0,11811074 0,1389606 ! hindbrain development GO:0030902 61 32 0,000 0,11811074 0,13889268 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,11811074 0,13882483 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,11811074 0,13875705 ! gene silencing GO:0016458 65 32 0,000 0,11811074 0,13868933 ! post-embryonic development GO:0009791 69 33 0,000 0,1215697 0,14268132 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1215697 0,14261175 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,1215697 0,14254225 ! ceramide metabolic process GO:0006672 64 33 0,000 0,1215697 0,14247282 ! formation of primary germ layer GO:0001704 72 33 0,000 0,1215697 0,14240346 ! cell fate specification GO:0001708 52 33 0,000 0,1215697 0,14233416 ! sterol transport GO:0015918 57 33 0,000 0,1215697 0,14226493 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,1215697 0,14219577 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1215697 0,14212667 ! adult locomotory behavior GO:0008344 59 33 0,000 0,1215697 0,14205765 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,1215697 0,14198869 ! glial cell differentiation GO:0010001 63 34 0,000 0,12501521 0,14594207 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12501521 0,14587129 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,12501521 0,14580058 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,12501521 0,14572994 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,12501521 0,14565937 ! mismatch repair GO:0006298 46 34 0,000 0,12501521 0,14558887 ! spermatid development GO:0007286 63 34 0,000 0,12501521 0,14551843 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,12501521 0,14544806 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12501521 0,14537777 ! negative regulation of secretion GO:0051048 63 35 0,000 0,12844732 0,14929674 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,12844732 0,14922465 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,12844732 0,14915263 ! odontogenesis GO:0042476 66 35 0,000 0,12844732 0,14908068 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,12844732 0,1490088 ! female gonad development GO:0008585 58 35 0,000 0,12844732 0,14893699 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,12844732 0,14886525 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,12844732 0,14879358 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,12844732 0,14872197 ! cytokine production GO:0001816 59 35 0,000 0,12844732 0,14865044 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,12844732 0,14857897 ! neural tube formation GO:0001841 67 35 0,000 0,12844732 0,14850757 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,13186609 0,15238703 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,13186609 0,15231387 ! cell junction organization GO:0034330 86 36 0,000 0,13186609 0,15224079 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,13186609 0,15216777 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,13186609 0,15209482 ! positive regulation of cell development GO:0010720 80 36 0,000 0,13186609 0,15202195 ! regulation of proteolysis GO:0030162 72 36 0,000 0,13186609 0,15194914 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,13186609 0,1518764 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,13186609 0,15180373 ! aerobic respiration GO:0009060 55 36 0,000 0,13186609 0,15173113 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,13186609 0,1516586 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,13186609 0,15158614 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13527155 0,15542662 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13527155 0,15535243 ! actomyosin structure organization GO:0031032 62 37 0,000 0,13527155 0,15527832 ! organic anion transport GO:0015711 68 37 0,000 0,13527155 0,15520427 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,13527155 0,15513029 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13527155 0,15505638 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,13527155 0,15498255 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13527155 0,15490878 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,13527155 0,15483509 ! glycogen metabolic process GO:0005977 61 37 0,000 0,13527155 0,15476146 ! pigment metabolic process GO:0042440 80 37 0,000 0,13527155 0,1546879 ! spermatid differentiation GO:0048515 66 37 0,000 0,13527155 0,15461442 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,13866377 0,15841644 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,13866377 0,15834126 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,13866377 0,15826614 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,13866377 0,1581911 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,13866377 0,15811613 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,13866377 0,15804123 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,13866377 0,1579664 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,13866377 0,15789164 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,13866377 0,15781695 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,13866377 0,15774233 ! glucan metabolic process GO:0044042 62 38 0,000 0,13866377 0,15766778 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,14204279 0,16143361 ! learning GO:0007612 77 39 0,000 0,14204279 0,1613574 ! organic ether metabolic process GO:0018904 55 39 0,000 0,14204279 0,16128125 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,14204279 0,16120517 ! ion transmembrane transport GO:0034220 66 39 0,000 0,14204279 0,16112917 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,14204279 0,16105323 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,14204279 0,16097737 ! RNA modification GO:0009451 57 39 0,000 0,14204279 0,16090158 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,14204279 0,16082586 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,14540867 0,16455939 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14540867 0,16448203 ! feeding behavior GO:0007631 59 40 0,000 0,14540867 0,16440473 ! negative regulation of binding GO:0051100 72 40 0,000 0,14540867 0,16432751 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14540867 0,16425036 ! maintenance of protein location GO:0045185 91 40 0,000 0,14540867 0,16417329 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,14876146 0,16787996 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,14876146 0,16780125 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,14876146 0,16772262 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,14876146 0,16764406 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,14876146 0,16756558 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,14876146 0,16748717 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,14876146 0,16740883 ! female gamete generation GO:0007292 61 41 0,000 0,14876146 0,16733056 ! polyol metabolic process GO:0019751 66 41 0,000 0,14876146 0,16725237 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,14876146 0,16717425 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,15210121 0,17084757 ! regulation of tube size GO:0035150 71 42 0,000 0,15210121 0,17076785 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,15210121 0,1706882 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,15210121 0,17060863 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,15210121 0,17052912 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,15210121 0,1704497 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,15210121 0,17037035 ! neuron migration GO:0001764 79 42 0,000 0,15210121 0,17029107 ! regulation of protein secretion GO:0050708 71 42 0,000 0,15210121 0,17021186 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,15542796 0,17385387 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,15542796 0,17377308 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,15542796 0,17369237 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,15542796 0,17361173 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,15542796 0,17353117 ! glucose transport GO:0015758 65 43 0,000 0,15542796 0,17345068 ! neural tube development GO:0021915 77 43 0,000 0,15542796 0,17337027 ! striated muscle contraction GO:0006941 77 43 0,000 0,15542796 0,17328993 ! phagocytosis GO:0006909 90 43 0,000 0,15542796 0,17320966 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15542796 0,17312947 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,15874177 0,17673887 ! hexose transport GO:0008645 67 44 0,000 0,15874177 0,17665712 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,15874177 0,17657545 ! male sex differentiation GO:0046661 76 44 0,000 0,15874177 0,17649385 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,15874177 0,17641233 ! developmental growth GO:0048589 82 44 0,000 0,15874177 0,17633088 ! maintenance of location in cell GO:0051651 97 44 0,000 0,15874177 0,17624951 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,16204268 0,1798315 ! glycolysis GO:0006096 65 45 0,000 0,16204268 0,17974859 ! leukocyte migration GO:0050900 68 45 0,000 0,16204268 0,17966576 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,16204268 0,179583 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,16204268 0,17950032 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,16204268 0,17941772 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,16204268 0,17933519 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,16204268 0,17925273 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,16204268 0,17917036 ! cell growth GO:0016049 84 45 0,000 0,16204268 0,17908806 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,16533076 0,18263811 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,16533076 0,18255429 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,16533076 0,18247055 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,16533076 0,18238689 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,16533076 0,1823033 ! positive regulation of defense response GO:0031349 76 47 0,000 0,16860604 0,18582965 ! endosome transport GO:0016197 108 47 0,000 0,16860604 0,18574456 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,16860604 0,18565956 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,16860604 0,18557462 ! JNK cascade GO:0007254 91 47 0,000 0,16860604 0,18548977 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,16860604 0,18540499 ! Notch signaling pathway GO:0007219 96 48 0,000 0,17186858 0,18890626 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,17186858 0,18882 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,17186858 0,18873382 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,17186858 0,18864772 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,17186858 0,18856169 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,17186858 0,18847575 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,17186858 0,18838988 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,17511842 0,19186471 ! regulation of action potential GO:0001508 95 49 0,000 0,17511842 0,19177738 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,17511842 0,19169013 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,17511842 0,19160296 ! regulation of ion transport GO:0043269 77 49 0,000 0,17511842 0,19151587 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,17511842 0,19142886 ! peptide metabolic process GO:0006518 76 49 0,000 0,17511842 0,19134192 ! response to temperature stimulus GO:0009266 76 49 0,000 0,17511842 0,19125507 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,17511842 0,19116829 ! endocrine system development GO:0035270 104 49 0,000 0,17511842 0,19108159 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,17511842 0,19099497 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,17511842 0,19090843 ! neuromuscular process GO:0050905 99 50 0,000 0,17835561 0,19434946 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,17835561 0,19426148 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,18158021 0,19768416 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,18158021 0,19759475 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,18158021 0,19750542 ! excretion GO:0007588 83 51 0,000 0,18158021 0,19741617 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,18158021 0,19732701 ! chromatin remodeling GO:0006338 109 51 0,000 0,18158021 0,19723792 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,18158021 0,19714891 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,18158021 0,19705999 ! membrane fusion GO:0006944 110 52 0,000 0,18479227 0,20045545 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,18479227 0,20036512 ! synapse organization GO:0050808 85 52 0,000 0,18479227 0,20027486 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,18799182 0,20365075 ! RNA catabolic process GO:0006401 93 53 0,000 0,18799182 0,2035591 ! regulation of translational initiation GO:0006446 82 53 0,000 0,18799182 0,20346753 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,18799182 0,20337604 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,18799182 0,20328463 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,18799182 0,20319331 ! cell maturation GO:0048469 100 53 0,000 0,18799182 0,20310207 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,18799182 0,20301091 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,19117892 0,20636001 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,19117892 0,20626748 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,19117892 0,20617502 ! cell recognition GO:0008037 85 54 0,000 0,19117892 0,20608265 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,19117892 0,20599036 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,19117892 0,20589815 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,19117892 0,20580603 ! chloride transport GO:0006821 90 55 0,000 0,19435361 0,20913005 ! glucose catabolic process GO:0006007 82 55 0,000 0,19435361 0,20903656 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,19435361 0,20894316 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,19435361 0,20884984 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,19435361 0,2087566 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,19435361 0,20866345 ! gastrulation GO:0007369 112 55 0,000 0,19435361 0,20857038 ! RNA elongation GO:0006354 79 55 0,000 0,19435361 0,20847739 ! nuclear export GO:0051168 97 55 0,000 0,19435361 0,20838449 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,19435361 0,20829167 ! regulation of actin filament length GO:0030832 105 56 0,000 0,19751595 0,21158655 ! sensory perception of smell GO:0007608 80 56 0,000 0,19751595 0,21149238 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,19751595 0,2113983 ! proton transport GO:0015992 94 56 0,000 0,19751595 0,21130431 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,20066599 0,21457883 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,20066599 0,2144835 ! maintenance of location GO:0051235 118 57 0,000 0,20066599 0,21438826 ! hydrogen transport GO:0006818 97 58 0,000 0,20380376 0,21764396 ! regulation of endocytosis GO:0030100 91 58 0,000 0,20380376 0,2175474 ! adult behavior GO:0030534 99 58 0,000 0,20380376 0,21745093 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,20380376 0,21735454 ! positive regulation of secretion GO:0051047 95 59 0,000 0,20692931 0,22059013 ! regulation of cellular component size GO:0032535 109 59 0,000 0,20692931 0,22049244 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,20692931 0,22039483 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,20692931 0,22029731 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,20692931 0,22019988 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,21004271 0,22341413 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,21004271 0,2233154 ! camera-type eye development GO:0043010 116 60 0,000 0,21004271 0,22321676 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,21004271 0,22311821 ! kidney development GO:0001822 122 60 0,000 0,21004271 0,22301975 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,21314398 0,2262128 ! mesoderm development GO:0007498 119 61 0,000 0,21314398 0,22611306 ! tRNA processing GO:0008033 89 61 0,000 0,21314398 0,22601341 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,21314398 0,22591384 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,21623318 0,2290872 ! gonad development GO:0008406 98 62 0,000 0,21623318 0,22898637 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,21931036 0,23214286 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,21931036 0,23204077 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,22237555 0,23518047 ! cell redox homeostasis GO:0045454 102 64 0,000 0,22237555 0,23507714 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,22237555 0,2349739 ! single fertilization GO:0007338 75 64 0,000 0,22237555 0,23487075 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,22542881 0,2379911 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,22542881 0,23788672 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,22542881 0,23778243 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,22542881 0,23767823 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,22847019 0,24077936 ! actin filament organization GO:0007015 148 66 0,000 0,22847019 0,24067394 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,22847019 0,24056861 ! extracellular matrix organization GO:0030198 133 66 0,000 0,22847019 0,24046337 ! secondary metabolic process GO:0019748 116 66 0,000 0,22847019 0,24035823 ! developmental maturation GO:0021700 116 66 0,000 0,22847019 0,24025318 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,23149972 0,2433326 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,23149972 0,24322634 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,23149972 0,24312018 ! hexose catabolic process GO:0019320 104 67 0,000 0,23149972 0,24301411 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,23149972 0,24290812 ! activation of immune response GO:0002253 105 67 0,000 0,23149972 0,24280224 ! amino acid transport GO:0006865 125 68 0,000 0,23451746 0,24586013 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,23451746 0,24575305 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,23451746 0,24564606 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,23451746 0,24553917 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,23451746 0,24543237 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,23451746 0,24532566 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,23752345 0,2483622 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,23752345 0,24825431 ! urogenital system development GO:0001655 137 69 0,000 0,23752345 0,24814651 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,23752345 0,24803881 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,23752345 0,2479312 ! antigen processing and presentation GO:0019882 104 69 0,000 0,23752345 0,24782368 ! appendage morphogenesis GO:0035107 135 70 0,000 0,24051773 0,25083904 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,24350036 0,25383963 ! reproductive structure development GO:0048608 113 71 0,000 0,24350036 0,25372969 ! appendage development GO:0048736 136 71 0,000 0,24350036 0,25361985 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,24350036 0,25351011 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,24350036 0,25340046 ! regulation of immune effector process GO:0002697 137 71 0,000 0,24350036 0,2532909 ! acute inflammatory response GO:0002526 113 72 0,000 0,24647137 0,25627057 ! carbohydrate transport GO:0008643 110 72 0,000 0,24647137 0,25615987 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,24647137 0,25604927 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,24647137 0,25593876 ! learning or memory GO:0007611 147 73 0,000 0,24943081 0,25890014 ! regulation of blood pressure GO:0008217 125 73 0,000 0,24943081 0,25878849 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,24943081 0,25867695 ! axon guidance GO:0007411 139 73 0,000 0,24943081 0,2585655 ! fertilization GO:0009566 90 73 0,000 0,24943081 0,25845414 ! transition metal ion transport GO:0000041 126 74 0,000 0,25237872 0,26139613 ! neurotransmitter transport GO:0006836 123 74 0,000 0,25237872 0,26128365 ! exocytosis GO:0006887 133 74 0,000 0,25237872 0,26117127 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,25237872 0,26105899 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,25237872 0,2609468 ! eye development GO:0001654 143 74 0,000 0,25237872 0,26083471 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,25531516 0,26375623 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,25531516 0,26364303 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,25531516 0,26352993 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,25531516 0,26341692 ! rhythmic process GO:0048511 128 75 0,000 0,25531516 0,26330401 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,25824015 0,26620643 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,25824015 0,26609242 ! defense response to bacterium GO:0042742 89 76 0,000 0,25824015 0,26597851 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,25824015 0,2658647 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,25824015 0,26575099 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,26115376 0,26863444 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,26115376 0,26851964 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,26115376 0,26840493 ! blood coagulation GO:0007596 146 78 0,000 0,26405602 0,2712719 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,26405602 0,27115612 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,26694697 0,27400786 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,26694697 0,27389101 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,26694697 0,27377426 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,26694697 0,27365761 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,26982667 0,27649189 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,26982667 0,27637419 ! inorganic anion transport GO:0015698 138 80 0,000 0,26982667 0,27625658 ! digestion GO:0007586 112 81 0,000 0,27269515 0,27907466 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,27269515 0,278956 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,27269515 0,27883745 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,27555245 0,28163942 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,27555245 0,28151983 ! response to nutrient GO:0007584 125 82 0,000 0,27555245 0,28140034 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,27555245 0,28128095 ! regulation of lyase activity GO:0051339 160 83 0,000 0,27839862 0,28406577 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,28123371 0,28683692 ! hemostasis GO:0007599 158 84 0,000 0,28123371 0,28671538 ! negative regulation of transport GO:0051051 153 84 0,000 0,28123371 0,28659394 ! regulation of ligase activity GO:0051340 142 84 0,000 0,28123371 0,28647261 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,28123371 0,28635138 ! nucleosome assembly GO:0006334 122 85 0,000 0,28405775 0,28910446 ! amine biosynthetic process GO:0009309 138 86 0,000 0,28687079 0,29184402 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,28687079 0,29172067 ! chromatin assembly GO:0031497 124 86 0,000 0,28687079 0,29159743 ! tube morphogenesis GO:0035239 176 86 0,000 0,28687079 0,29147429 ! alcohol catabolic process GO:0046164 130 86 0,000 0,28687079 0,29135125 ! amine transport GO:0015837 155 86 0,000 0,28687079 0,29122832 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,28967287 0,29394893 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,28967287 0,29382501 ! regulation of protein transport GO:0051223 154 87 0,000 0,28967287 0,29370119 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,29246403 0,29640626 ! regulation of neurological system process GO:0031644 148 88 0,000 0,29246403 0,29628146 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,29246403 0,29615676 ! cellular defense response GO:0006968 114 89 0,000 0,29524432 0,29884637 ! ossification GO:0001503 188 90 0,000 0,29801377 0,30152276 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,29801377 0,30139602 ! sex differentiation GO:0007548 145 90 0,000 0,29801377 0,30126938 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,29801377 0,30114285 ! bone development GO:0060348 189 91 0,000 0,30077243 0,30380289 ! sterol metabolic process GO:0016125 152 91 0,000 0,30077243 0,3036754 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,30077243 0,30354802 ! regulation of defense response GO:0031347 149 92 0,000 0,30352035 0,30619285 ! nucleosome organization GO:0034728 138 92 0,000 0,30352035 0,30606453 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,30352035 0,3059363 ! vitamin metabolic process GO:0006766 139 92 0,000 0,30352035 0,30580819 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,30625755 0,30843687 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,30625755 0,30830781 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,30625755 0,30817887 ! regulation of membrane potential GO:0042391 164 93 0,000 0,30625755 0,30805003 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,30898409 0,31066265 ! regulation of T cell activation GO:0050863 158 94 0,000 0,30898409 0,31053289 ! forebrain development GO:0030900 188 95 0,000 0,31170001 0,31313161 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,31170001 0,31300092 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,31440534 0,31558583 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,31440534 0,31545423 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,31710012 0,31802538 ! protein ubiquitination GO:0016567 217 97 0,000 0,31710012 0,31789287 ! hormone metabolic process GO:0042445 157 97 0,000 0,31710012 0,31776047 ! regulation of protein localization GO:0032880 176 97 0,000 0,31710012 0,31762818 ! response to virus GO:0009615 160 98 0,000 0,31978441 0,32018364 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,31978441 0,32005045 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,31978441 0,31991737 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,32245823 0,32245823