pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/528-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 7,69E-13 1,85E-09 ! regulation of ossification GO:0030278 117 50 6,000 1,227E-09 1,476E-06 ! cartilage development GO:0051216 90 52 6,000 1,633E-09 1,31E-06 ! epithelial to mesenchymal transition GO:0001837 28 15 4,000 2,801E-09 1,685E-06 ! regulation of bone remodeling GO:0046850 137 57 6,000 3,174E-09 1,527E-06 ! regulation of tissue remodeling GO:0034103 140 58 6,000 3,597E-09 1,443E-06 ! mesenchymal cell development GO:0014031 87 40 5,000 1,274E-08 4,379E-06 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! collagen fibril organization GO:0030199 59 21 4,000 1,862E-08 5,599E-06 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 2,659E-08 7,109E-06 ! osteoblast differentiation GO:0001649 60 25 4,000 4,798E-08 1,154E-05 ! chondrocyte differentiation GO:0002062 24 11 3,000 8,004E-08 1,751E-05 ! ossification GO:0001503 188 90 6,000 8,04E-08 1,612E-05 ! bone development GO:0060348 189 91 6,000 8,681E-08 1,607E-05 ! cell cycle arrest GO:0007050 213 100 6,000 1,667E-07 2,864E-05 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 2,405E-07 3,858E-05 ! neutrophil chemotaxis GO:0030593 27 17 3,000 5,666E-07 8,52E-05 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 2,000 6,289E-07 8,9E-05 ! positive regulation of ossification GO:0045778 47 20 3,000 1,143E-06 1,527E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 1,143E-06 1,447E-04 ! regulation of gene-specific transcription GO:0032583 96 46 4,000 1,157E-06 1,392E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 1,254E-06 1,437E-04 ! nuclear migration GO:0007097 12 6 2,000 1,254E-06 1,371E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 1,254E-06 1,312E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of osteoblast differentiation GO:0045669 49 21 3,000 1,407E-06 1,411E-04 ! positive regulation of bone remodeling GO:0046852 51 22 3,000 1,714E-06 1,65E-04 GO:0034105|positive regulation of tissue remodeling, ! positive regulation of growth GO:0045927 90 52 4,000 2,152E-06 1,992E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 2,188E-06 1,95E-04 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 2,000 2,188E-06 1,88E-04 ! macrophage differentiation GO:0030225 11 7 2,000 2,188E-06 1,815E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 2,188E-06 1,755E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 2,188E-06 1,698E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 2,188E-06 1,645E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 2,475E-06 1,805E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 3,461E-06 2,449E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 3,000 3,461E-06 2,379E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 3,461E-06 2,313E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 65 26 3,000 3,461E-06 2,25E-04 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 2,000 3,491E-06 2,21E-04 ! ER overload response GO:0006983 12 8 2,000 3,491E-06 2,154E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 3,491E-06 2,1E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 3,491E-06 2,048E-04 ! peptidyl-tyrosine modification GO:0018212 50 28 3,000 4,71E-06 2,698E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 4,787E-06 2,678E-04 ! induction of positive chemotaxis GO:0050930 15 9 2,000 5,221E-06 2,855E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 5,221E-06 2,791E-04 ! extracellular matrix organization GO:0030198 133 66 4,000 7,077E-06 3,701E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 7,436E-06 3,807E-04 ! negative regulation of cell growth GO:0030308 132 67 4,000 7,623E-06 3,821E-04 ! response to mechanical stimulus GO:0009612 57 32 3,000 8,171E-06 4,012E-04 ! negative regulation of cell size GO:0045792 134 69 4,000 8,814E-06 4,241E-04 ! leukocyte chemotaxis GO:0030595 50 33 3,000 9,269E-06 4,373E-04 GO:0060326|cell chemotaxis, ! detection of mechanical stimulus GO:0050982 22 11 2,000 1,019E-05 4,717E-04 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 1,019E-05 4,628E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 1,019E-05 4,542E-04 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 19 11 2,000 1,019E-05 4,46E-04 ! positive regulation of cell development GO:0010720 80 36 3,000 1,322E-05 5,679E-04 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 1,355E-05 5,721E-04 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 30 12 2,000 1,355E-05 5,622E-04 ! gland morphogenesis GO:0022612 29 12 2,000 1,355E-05 5,527E-04 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 1,355E-05 5,435E-04 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 1,478E-05 5,828E-04 ! carbohydrate homeostasis GO:0033500 53 38 3,000 1,646E-05 6,388E-04 GO:0042593|glucose homeostasis, ! cellular response to hormone stimulus GO:0032870 167 82 4,000 2,053E-05 7,84E-04 ! hair follicle morphogenesis GO:0031069 26 14 2,000 2,229E-05 8,381E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 2,229E-05 8,252E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 2,229E-05 8,127E-04 GO:0060675|ureteric bud morphogenesis, ! response to gamma radiation GO:0010332 28 14 2,000 2,229E-05 8,006E-04 ! negative regulation of growth GO:0045926 155 84 4,000 2,308E-05 8,165E-04 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 2,778E-05 9,688E-04 ! leukocyte migration GO:0050900 68 45 3,000 3,252E-05 1,118E-03 ! filopodium assembly GO:0046847 32 16 2,000 3,41E-05 1,155E-03 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 3,41E-05 1,139E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 3,55E-05 1,17E-03 ! pigmentation GO:0043473 100 46 3,000 3,55E-05 1,154E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 3,55E-05 1,139E-03 ! myoblast differentiation GO:0045445 45 17 2,000 4,128E-05 1,307E-03 ! microspike assembly GO:0030035 36 17 2,000 4,128E-05 1,29E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 4,397E-05 1,356E-03 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 4,621E-05 1,407E-03 ! epidermis morphogenesis GO:0048730 40 18 2,000 4,939E-05 1,485E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 4,939E-05 1,467E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 5,848E-05 1,716E-03 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 2,000 5,848E-05 1,695E-03 ! regulation of neuron apoptosis GO:0043523 100 53 3,000 6,234E-05 1,786E-03 ! response to UV GO:0009411 104 53 3,000 6,234E-05 1,765E-03 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 2,000 6,86E-05 1,919E-03 ! response to alkaloid GO:0043279 38 20 2,000 6,86E-05 1,897E-03 ! pancreas development GO:0031016 35 20 2,000 6,86E-05 1,876E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 6,86E-05 1,855E-03 ! regulation of glucose import GO:0046324 29 20 2,000 6,86E-05 1,834E-03 GO:0010827|regulation of glucose transport, ! heart morphogenesis GO:0003007 97 55 3,000 7,216E-05 1,908E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 7,747E-05 2,026E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 7,98E-05 2,064E-03 ! cell aging GO:0007569 44 21 2,000 7,98E-05 2,043E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 7,98E-05 2,021E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 7,98E-05 2E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 8,306E-05 2,06E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 9,213E-05 2,262E-03 ! ureteric bud development GO:0001657 43 22 2,000 9,213E-05 2,239E-03 ! skeletal system morphogenesis GO:0048705 105 59 3,000 9,511E-05 2,288E-03 ! regulation of heart contraction GO:0008016 110 60 3,000 1,016E-04 2,42E-03 ! negative regulation of response to stimulus GO:0048585 100 60 3,000 1,016E-04 2,396E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 1,056E-04 2,468E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 1,056E-04 2,444E-03 ! regulation of bone mineralization GO:0030500 49 23 2,000 1,056E-04 2,421E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 1,204E-04 2,732E-03 ! regulation of behavior GO:0050795 43 24 2,000 1,204E-04 2,707E-03 ! protein tetramerization GO:0051262 52 24 2,000 1,204E-04 2,682E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 1,307E-04 2,886E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 1,364E-04 2,983E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,364E-04 2,956E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 1,364E-04 2,93E-03 ! interaction with host GO:0051701 62 25 2,000 1,364E-04 2,904E-03 ! regulation of biomineral formation GO:0070167 51 25 2,000 1,364E-04 2,879E-03 ! molting cycle process GO:0022404 50 26 2,000 1,537E-04 3,216E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,563E-04 3,241E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 1,563E-04 3,213E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,588E-04 3,238E-03 ! Notch receptor processing GO:0007220 8 5 1,000 1,588E-04 3,211E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 1,000 1,588E-04 3,184E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,588E-04 3,158E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,588E-04 3,132E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 1,588E-04 3,107E-03 ! valine metabolic process GO:0006573 10 5 1,000 1,588E-04 3,082E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,588E-04 3,057E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 1,588E-04 3,033E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 1,588E-04 3,009E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,588E-04 2,985E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 1,588E-04 2,962E-03 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 11 5 1,000 1,588E-04 2,94E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 1,588E-04 2,917E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 1,588E-04 2,895E-03 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,588E-04 2,873E-03 ! stem cell division GO:0017145 11 5 1,000 1,588E-04 2,852E-03 GO:0048103|somatic stem cell division, ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,655E-04 2,95E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,724E-04 3,051E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 1,724E-04 3,028E-03 ! fat cell differentiation GO:0045444 50 27 2,000 1,724E-04 3,006E-03 ! mitochondrial membrane organization GO:0007006 57 27 2,000 1,724E-04 2,985E-03 ! negative regulation of protein modification process GO:0031400 60 28 2,000 1,926E-04 3,309E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 1,926E-04 3,286E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 2,065E-04 3,499E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 2,065E-04 3,475E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 2,142E-04 3,578E-03 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 2,142E-04 3,553E-03 ! regulation of peptide secretion GO:0002791 47 29 2,000 2,142E-04 3,529E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 2,142E-04 3,505E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 2,373E-04 3,857E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 2,376E-04 3,837E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! male sex determination GO:0030238 15 6 1,000 2,376E-04 3,811E-03 ! neural nucleus development GO:0048857 14 6 1,000 2,376E-04 3,786E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 2,376E-04 3,761E-03 ! salivary gland morphogenesis GO:0007435 13 6 1,000 2,376E-04 3,737E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,376E-04 3,712E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 2,619E-04 4,065E-03 ! metanephros development GO:0001656 74 32 2,000 2,882E-04 4,444E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 2,882E-04 4,416E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 2,882E-04 4,388E-03 ! BMP signaling pathway GO:0030509 64 32 2,000 2,882E-04 4,36E-03 ! hindbrain development GO:0030902 61 32 2,000 2,882E-04 4,333E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 2,951E-04 4,411E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 2,951E-04 4,384E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 3,248E-04 4,794E-03 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 3,000 3,248E-04 4,765E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 3,318E-04 4,838E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,318E-04 4,809E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,318E-04 4,78E-03 ! fibril organization GO:0043206 16 7 1,000 3,318E-04 4,752E-03 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 3,318E-04 4,723E-03 ! regulation of odontogenesis GO:0042481 13 7 1,000 3,318E-04 4,696E-03 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 3,318E-04 4,668E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 3,318E-04 4,641E-03 ! microtubule nucleation GO:0007020 20 7 1,000 3,318E-04 4,614E-03 ! organ growth GO:0035265 15 7 1,000 3,318E-04 4,588E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 3,318E-04 4,562E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,318E-04 4,536E-03 ! response to tumor cell GO:0002347 13 7 1,000 3,318E-04 4,51E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 3,318E-04 4,485E-03 ! peptidyl-threonine modification GO:0018210 25 7 1,000 3,318E-04 4,46E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 3,318E-04 4,435E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 3,318E-04 4,41E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 3,456E-04 4,569E-03 ! response to oxygen levels GO:0070482 176 83 3,000 3,565E-04 4,688E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 3,769E-04 4,929E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 3,769E-04 4,902E-03 ! mitochondrion organization GO:0007005 148 86 3,000 4,082E-04 5,281E-03 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 2,000 4,1E-04 5,275E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! DNA integrity checkpoint GO:0031570 75 36 2,000 4,1E-04 5,247E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 4,1E-04 5,219E-03 ! succinate metabolic process GO:0006105 14 8 1,000 4,412E-04 5,587E-03 ! pigment granule organization GO:0048753 16 8 1,000 4,412E-04 5,558E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,412E-04 5,529E-03 ! regulation of pigmentation during development GO:0048070 24 8 1,000 4,412E-04 5,5E-03 ! melanin metabolic process GO:0006582 15 8 1,000 4,412E-04 5,472E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 4,412E-04 5,444E-03 ! response to UV-B GO:0010224 16 8 1,000 4,412E-04 5,416E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 4,412E-04 5,389E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 4,412E-04 5,361E-03 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 4,412E-04 5,334E-03 GO:0000076|DNA replication checkpoint, ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 4,448E-04 5,351E-03 ! positive regulation of protein modification process GO:0031401 136 88 3,000 4,455E-04 5,333E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 5,493E-04 6,543E-03 ! regulation of hormone secretion GO:0046883 62 40 2,000 5,607E-04 6,646E-03 ! multicellular organismal metabolic process GO:0044236 57 40 2,000 5,607E-04 6,613E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 5,658E-04 6,64E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,658E-04 6,608E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 5,658E-04 6,576E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 5,658E-04 6,545E-03 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 5,658E-04 6,513E-03 ! T cell selection GO:0045058 23 9 1,000 5,658E-04 6,482E-03 ! phosphagen metabolic process GO:0006599 12 9 1,000 5,658E-04 6,452E-03 GO:0006600|creatine metabolic process, ! behavioral fear response GO:0001662 22 9 1,000 5,658E-04 6,421E-03 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 16 9 1,000 5,658E-04 6,391E-03 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 5,658E-04 6,361E-03 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 5,658E-04 6,331E-03 ! regulation of telomere maintenance GO:0032204 14 9 1,000 5,658E-04 6,302E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 5,952E-04 6,6E-03 ! T cell differentiation GO:0030217 81 41 2,000 6,032E-04 6,657E-03 ! interphase GO:0051325 213 98 3,000 6,692E-04 7,352E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 6,942E-04 7,593E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 6,942E-04 7,558E-03 ! skeletal muscle tissue development GO:0007519 186 99 3,000 6,952E-04 7,535E-03 GO:0060538|skeletal muscle organ development, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,054E-04 7,61E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 7,054E-04 7,576E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 7,054E-04 7,543E-03 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 7,054E-04 7,509E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 7,054E-04 7,476E-03 ! positive regulation of heart contraction GO:0045823 16 10 1,000 7,054E-04 7,443E-03 ! B cell proliferation GO:0042100 18 10 1,000 7,054E-04 7,411E-03 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 7,054E-04 7,379E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 7,054E-04 7,347E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,054E-04 7,315E-03 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell activation GO:0046631 23 10 1,000 7,054E-04 7,284E-03 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 7,054E-04 7,253E-03 ! salivary gland development GO:0007431 27 10 1,000 7,054E-04 7,222E-03 ! midbrain development GO:0030901 13 10 1,000 7,054E-04 7,191E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 7,054E-04 7,161E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 7,054E-04 7,131E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 7,054E-04 7,101E-03 ! response to nicotine GO:0035094 20 10 1,000 7,054E-04 7,071E-03 ! B cell differentiation GO:0030183 107 44 2,000 7,429E-04 7,416E-03 ! detection of stimulus involved in sensory perception GO:0050906 66 45 2,000 7,936E-04 7,89E-03 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 7,936E-04 7,858E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 8,598E-04 8,479E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 8,598E-04 8,444E-03 ! negative regulation of ossification GO:0030279 26 11 1,000 8,598E-04 8,41E-03 ! oocyte differentiation GO:0009994 18 11 1,000 8,598E-04 8,376E-03 ! thymus development GO:0048538 27 11 1,000 8,598E-04 8,342E-03 ! cardiac cell differentiation GO:0035051 31 11 1,000 8,598E-04 8,308E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 8,598E-04 8,275E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 9,016E-04 8,642E-03 ! mitochondrial transport GO:0006839 82 48 2,000 9,589E-04 9,155E-03 ! activation of caspase activity GO:0006919 84 48 2,000 9,589E-04 9,119E-03 ! regulation of inflammatory response GO:0050727 75 48 2,000 9,589E-04 9,083E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 1,018E-03 9,609E-03 ! detection of abiotic stimulus GO:0009582 74 49 2,000 1,018E-03 9,572E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,029E-03 9,634E-03 ! virus-host interaction GO:0019048 29 12 1,000 1,029E-03 9,597E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,029E-03 9,56E-03 ! cartilage condensation GO:0001502 20 12 1,000 1,029E-03 9,523E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 1,029E-03 9,487E-03 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,029E-03 9,451E-03 ! focal adhesion formation GO:0048041 35 12 1,000 1,029E-03 9,415E-03 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,029E-03 9,379E-03 GO:0006509|membrane protein ectodomain proteolysis, ! entry into host cell GO:0030260 32 12 1,000 1,029E-03 9,344E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 1,000 1,029E-03 9,308E-03 ! histone acetylation GO:0016573 26 12 1,000 1,029E-03 9,274E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,029E-03 9,239E-03 ! T cell homeostasis GO:0043029 25 12 1,000 1,029E-03 9,205E-03 ! spleen development GO:0048536 22 12 1,000 1,029E-03 9,171E-03 ! digestive tract morphogenesis GO:0048546 26 12 1,000 1,029E-03 9,137E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of cell projection organization GO:0031344 121 50 2,000 1,08E-03 9,556E-03 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,144E-03 0,01008637 ! regulation of muscle contraction GO:0006937 81 52 2,000 1,211E-03 0,01063376 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,211E-03 0,01059509 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,213E-03 0,01057442 ! plasma membrane organization GO:0007009 24 13 1,000 1,213E-03 0,01053625 ! response to X-ray GO:0010165 25 13 1,000 1,213E-03 0,01049835 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 1,213E-03 0,01046072 ! exocrine system development GO:0035272 32 13 1,000 1,213E-03 0,01042336 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,213E-03 0,01038626 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 1,213E-03 0,01034943 ! regulation of cellular pH GO:0030641 22 13 1,000 1,213E-03 0,01031286 ! regulation of epidermis development GO:0045682 19 13 1,000 1,213E-03 0,01027655 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,411E-03 0,01191587 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 1,411E-03 0,01187421 ! positive regulation of bone mineralization GO:0030501 29 14 1,000 1,411E-03 0,01183283 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 1,411E-03 0,01179175 ! positive regulation of caspase activity GO:0043280 95 55 2,000 1,425E-03 0,01186389 GO:0010952|positive regulation of peptidase activity, ! aging GO:0007568 103 55 2,000 1,425E-03 0,01182298 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 1,425E-03 0,01178235 ! skeletal muscle fiber development GO:0048741 111 56 2,000 1,501E-03 0,01237051 ! muscle fiber development GO:0048747 112 57 2,000 1,58E-03 0,0129753 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,624E-03 0,01329321 ! positive regulation of cell size GO:0045793 27 15 1,000 1,624E-03 0,01324815 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 1,624E-03 0,01320339 ! glycoprotein catabolic process GO:0006516 26 15 1,000 1,624E-03 0,01315894 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,624E-03 0,01311478 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,624E-03 0,01307092 ! positive regulation of biomineral formation GO:0070169 30 15 1,000 1,624E-03 0,01302735 ! dopamine metabolic process GO:0042417 35 15 1,000 1,624E-03 0,01298407 ! lymphocyte homeostasis GO:0002260 30 15 1,000 1,624E-03 0,01294107 ! positive regulation of secretion GO:0051047 95 59 2,000 1,745E-03 0,01385925 ! establishment of organelle localization GO:0051656 109 59 2,000 1,745E-03 0,01381366 ! kidney development GO:0001822 122 60 2,000 1,832E-03 0,01445084 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,852E-03 0,01455817 ! startle response GO:0001964 28 16 1,000 1,852E-03 0,01451075 ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,852E-03 0,01446363 ! negative regulation of immune response GO:0050777 35 16 1,000 1,852E-03 0,01441683 ! DNA replication initiation GO:0006270 27 16 1,000 1,852E-03 0,01437032 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,852E-03 0,01432411 ! defense response to virus GO:0051607 37 16 1,000 1,852E-03 0,0142782 ! regulation of protein complex assembly GO:0043254 117 61 2,000 1,921E-03 0,01476675 ! ear development GO:0043583 103 62 2,000 2,013E-03 0,01542319 ! viral reproductive process GO:0022415 126 62 2,000 2,013E-03 0,01537423 ! regulation of homeostatic process GO:0032844 134 62 2,000 2,013E-03 0,01532557 ! metencephalon development GO:0022037 30 17 1,000 2,093E-03 0,01588495 ! regulation of viral genome replication GO:0045069 28 17 1,000 2,093E-03 0,015835 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,093E-03 0,01578536 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,093E-03 0,01573603 ! regulation of protein binding GO:0043393 33 17 1,000 2,093E-03 0,01568701 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 2,093E-03 0,01563829 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 2,093E-03 0,01558988 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 2,093E-03 0,01554176 ! regulation of lipid metabolic process GO:0019216 115 63 2,000 2,107E-03 0,01560072 ! detection of external stimulus GO:0009581 91 63 2,000 2,107E-03 0,01555287 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,107E-03 0,01550531 ! myeloid cell differentiation GO:0030099 111 65 2,000 2,304E-03 0,01690428 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,348E-03 0,0171736 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,348E-03 0,01712156 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 1,000 2,348E-03 0,01706984 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 2,348E-03 0,01701842 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 2,348E-03 0,01696732 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,348E-03 0,01691652 ! cell projection assembly GO:0030031 120 66 2,000 2,407E-03 0,0172888 ! activation of MAPK activity GO:0000187 115 67 2,000 2,513E-03 0,01799289 ! lung development GO:0030324 144 67 2,000 2,513E-03 0,0179395 ! skin development GO:0043588 36 19 1,000 2,618E-03 0,01863397 ! lipid phosphorylation GO:0046834 35 19 1,000 2,618E-03 0,018579 ! pigmentation during development GO:0048066 41 19 1,000 2,618E-03 0,01852436 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 1,000 2,618E-03 0,01847003 ! cellular pigmentation GO:0033059 36 19 1,000 2,618E-03 0,01841603 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 2,621E-03 0,0183856 ! viral reproduction GO:0016032 134 68 2,000 2,621E-03 0,01833216 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 2,621E-03 0,01827902 ! cell cycle checkpoint GO:0000075 137 69 2,000 2,732E-03 0,01899929 ! urogenital system development GO:0001655 137 69 2,000 2,732E-03 0,01894454 ! respiratory tube development GO:0030323 150 70 2,000 2,846E-03 0,01967859 ! protein amino acid acetylation GO:0006473 39 20 1,000 2,901E-03 0,01999929 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 2,901E-03 0,01994215 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 2,901E-03 0,01988533 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 2,901E-03 0,01982884 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 2,901E-03 0,01977267 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 2,901E-03 0,01971681 ! humoral immune response GO:0006959 109 71 2,000 2,963E-03 0,02008312 ! B cell activation GO:0042113 160 71 2,000 2,963E-03 0,02002671 ! regulation of caspase activity GO:0043281 122 72 2,000 3,083E-03 0,02077839 ! respiratory system development GO:0060541 153 72 2,000 3,083E-03 0,02072035 ! ovarian follicle development GO:0001541 35 21 1,000 3,198E-03 0,02143246 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 3,198E-03 0,02137292 ! oogenesis GO:0048477 36 21 1,000 3,198E-03 0,02131372 ! response to cytokine stimulus GO:0034097 63 21 1,000 3,198E-03 0,02125484 ! gut development GO:0048565 39 21 1,000 3,198E-03 0,02119629 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 3,332E-03 0,02202174 ! eye development GO:0001654 143 74 2,000 3,332E-03 0,02196141 ! organelle localization GO:0051640 136 74 2,000 3,332E-03 0,0219014 ! lymphocyte differentiation GO:0030098 167 75 2,000 3,46E-03 0,02268577 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 3,509E-03 0,02293889 ! regeneration GO:0031099 41 22 1,000 3,509E-03 0,02287672 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 3,509E-03 0,0228149 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,509E-03 0,0227534 ! apoptotic nuclear changes GO:0030262 32 22 1,000 3,509E-03 0,02269223 ! renal system process GO:0003014 41 22 1,000 3,509E-03 0,0226314 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,509E-03 0,02257089 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 3,509E-03 0,0225107 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,509E-03 0,02245083 ! positive regulation of DNA replication GO:0045740 43 23 1,000 3,833E-03 0,02445957 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 3,833E-03 0,02439486 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 3,833E-03 0,0243305 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 3,833E-03 0,02426647 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 3,833E-03 0,02420278 ! sex determination GO:0007530 47 23 1,000 3,833E-03 0,02413942 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 3,833E-03 0,02407639 ! regulation of viral reproduction GO:0050792 38 23 1,000 3,833E-03 0,02401369 ! protein oligomerization GO:0051259 139 78 2,000 3,865E-03 0,02415219 ! activation of protein kinase activity GO:0032147 147 79 2,000 4,006E-03 0,0249679 ! regulation of peptidase activity GO:0052547 134 79 2,000 4,006E-03 0,02490339 ! regulation of adenylate cyclase activity GO:0045761 156 80 2,000 4,15E-03 0,02573213 ! response to metal ion GO:0010038 140 80 2,000 4,15E-03 0,02566598 ! muscle cell differentiation GO:0042692 159 80 2,000 4,15E-03 0,02560017 ! protein import into nucleus GO:0006606 158 80 2,000 4,15E-03 0,0255347 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,17E-03 0,02559496 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 4,17E-03 0,02552984 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 4,17E-03 0,02546504 ! multicellular organismal response to stress GO:0033555 49 24 1,000 4,17E-03 0,02540057 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 4,17E-03 0,02533643 ! lymphocyte proliferation GO:0046651 48 24 1,000 4,17E-03 0,02527261 ! leukocyte homeostasis GO:0001776 44 24 1,000 4,17E-03 0,02520911 ! T cell activation GO:0042110 168 81 2,000 4,297E-03 0,02590981 ! nuclear import GO:0051170 161 81 2,000 4,297E-03 0,02584503 ! regulation of cAMP biosynthetic process GO:0030817 161 82 2,000 4,447E-03 0,02668203 ! response to drug GO:0042493 143 82 2,000 4,447E-03 0,02661565 ! response to nutrient GO:0007584 125 82 2,000 4,447E-03 0,02654961 ! regulation of cyclase activity GO:0031279 159 82 2,000 4,447E-03 0,02648389 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 4,521E-03 0,02685715 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 4,521E-03 0,026791 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 4,521E-03 0,02672517 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 4,521E-03 0,02665967 ! response to starvation GO:0042594 42 25 1,000 4,521E-03 0,02659449 ! negative regulation of cell development GO:0010721 73 25 1,000 4,521E-03 0,02652962 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 4,521E-03 0,02646507 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,521E-03 0,02640084 ! regulation of lyase activity GO:0051339 160 83 2,000 4,6E-03 0,02680037 ! regulation of cAMP metabolic process GO:0030814 168 84 2,000 4,757E-03 0,02764551 ! negative regulation of transport GO:0051051 153 84 2,000 4,757E-03 0,0275789 ! embryonic pattern specification GO:0009880 44 26 1,000 4,885E-03 0,02825181 ! initiation of viral infection GO:0019059 57 26 1,000 4,885E-03 0,02818406 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 4,885E-03 0,02811663 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 4,885E-03 0,02804953 ! leukocyte proliferation GO:0070661 52 26 1,000 4,885E-03 0,02798274 GO:0032943|mononuclear cell proliferation, ! response to inorganic substance GO:0010035 153 86 2,000 5,08E-03 0,02903011 ! tube morphogenesis GO:0035239 176 86 2,000 5,08E-03 0,02896132 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 2,000 5,246E-03 0,02983808 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 2,000 5,246E-03 0,02976771 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,262E-03 0,02978772 ! protein amino acid acylation GO:0043543 55 27 1,000 5,262E-03 0,0297178 ! male gonad development GO:0008584 44 27 1,000 5,262E-03 0,0296482 ! response to toxin GO:0009636 47 27 1,000 5,262E-03 0,02957893 ! base-excision repair GO:0006284 41 27 1,000 5,262E-03 0,02950998 ! regulation of chromosome organization GO:0033044 42 27 1,000 5,262E-03 0,02944135 ! glutathione metabolic process GO:0006749 39 27 1,000 5,262E-03 0,02937304 ! gland development GO:0048732 206 88 2,000 5,415E-03 0,03016005 ! regulation of cell adhesion GO:0030155 212 89 2,000 5,588E-03 0,03104992 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 2,000 5,764E-03 0,03195384 ! regulation of pH GO:0006885 43 29 1,000 6,054E-03 0,0334875 ! catechol metabolic process GO:0009712 54 29 1,000 6,054E-03 0,03341069 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 1,000 6,054E-03 0,03333424 ! response to organic cyclic substance GO:0014070 55 29 1,000 6,054E-03 0,03325813 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 6,054E-03 0,03318237 ! tissue homeostasis GO:0001894 48 29 1,000 6,054E-03 0,03310696 GO:0048871|multicellular organismal homeostasis, ! regulation of defense response GO:0031347 149 92 2,000 6,126E-03 0,03342058 ! regulation of nucleotide metabolic process GO:0006140 182 93 2,000 6,312E-03 0,0343568 ! phenol metabolic process GO:0018958 55 30 1,000 6,47E-03 0,03513948 ! cell junction assembly GO:0034329 78 30 1,000 6,47E-03 0,03506034 ! eye morphogenesis GO:0048592 60 30 1,000 6,47E-03 0,03498155 ! regulation of B cell activation GO:0050864 50 30 1,000 6,47E-03 0,03490312 ! response to heat GO:0009408 50 30 1,000 6,47E-03 0,03482504 ! positive regulation of immune response GO:0050778 156 96 2,000 6,889E-03 0,0369994 ! detection of stimulus GO:0051606 151 96 2,000 6,889E-03 0,03691699 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 6,898E-03 0,03688201 ! collagen metabolic process GO:0032963 45 31 1,000 6,898E-03 0,03680023 ! ovulation cycle process GO:0022602 49 31 1,000 6,898E-03 0,03671882 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 6,898E-03 0,03663776 ! mesoderm formation GO:0001707 69 31 1,000 6,898E-03 0,03655706 ! regulation of protein localization GO:0032880 176 97 2,000 7,089E-03 0,03748418 ! response to hydrogen peroxide GO:0042542 50 32 1,000 7,339E-03 0,03872181 ! ovulation cycle GO:0042698 51 32 1,000 7,339E-03 0,03863708 ! positive regulation of catabolic process GO:0009896 64 32 1,000 7,339E-03 0,03855272 ! DNA damage checkpoint GO:0000077 71 33 1,000 7,792E-03 0,0408437 ! post-embryonic development GO:0009791 69 33 1,000 7,792E-03 0,04075491 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 7,792E-03 0,0406665 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 7,792E-03 0,04057848 ! formation of primary germ layer GO:0001704 72 33 1,000 7,792E-03 0,04049084 ! adult locomotory behavior GO:0008344 59 33 1,000 7,792E-03 0,04040357 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 8,257E-03 0,04272471 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 8,257E-03 0,04263303 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 8,257E-03 0,04254173 ! mesoderm morphogenesis GO:0048332 76 34 1,000 8,257E-03 0,04245083 ! biogenic amine biosynthetic process GO:0042401 62 34 1,000 8,257E-03 0,04236032 ! regulation of muscle development GO:0048634 70 35 1,000 8,735E-03 0,04471508 ! odontogenesis GO:0042476 66 35 1,000 8,735E-03 0,04462015 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 8,735E-03 0,04452561 ! female gonad development GO:0008585 58 35 1,000 8,735E-03 0,04443148 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 9,225E-03 0,04682343 ! cell junction organization GO:0034330 86 36 1,000 9,225E-03 0,04672486 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 9,726E-03 0,04916259 ! regulation of protein stability GO:0031647 73 37 1,000 9,726E-03 0,04905952 ! glycogen metabolic process GO:0005977 61 37 1,000 9,726E-03 0,04895689 ! pigment metabolic process GO:0042440 80 37 1,000 9,726E-03 0,04885468 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,01023986 0,0513273 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01023986 0,05122059 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01023986 0,05111432 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01023986 0,05100849 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,01023986 0,0509031 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01023986 0,05079815 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,01023986 0,05069363 ! glucan metabolic process GO:0044042 62 38 1,000 0,01023986 0,05058953 GO:0006073|cellular glucan metabolic process, ! ear morphogenesis GO:0042471 60 39 1,000 0,01076525 0,0530762 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01076525 0,05296766 ! segmentation GO:0035282 67 39 1,000 0,01076525 0,05285957 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,01130233 0,05538372 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,011851 0,05795429 ! gliogenesis GO:0042063 88 41 1,000 0,011851 0,05783674 ! female gamete generation GO:0007292 61 41 1,000 0,011851 0,05771966 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01241117 0,0603258 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,01241117 0,06020417 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01241117 0,06008304 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,01298272 0,06272377 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01298272 0,06259807 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01356557 0,06527755 ! male sex differentiation GO:0046661 76 44 1,000 0,01356557 0,06514725 ! double-strand break repair GO:0006302 81 44 1,000 0,01356557 0,06501748 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,01356557 0,06488822 ! developmental growth GO:0048589 82 44 1,000 0,01356557 0,06475947 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01415962 0,06746147 ! cell growth GO:0016049 84 45 1,000 0,01415962 0,06732815 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,01476476 0,07006709 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,01476476 0,06992916 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01476476 0,06979178 ! response to calcium ion GO:0051592 81 47 1,000 0,0153809 0,07256167 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0153809 0,07241967 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,01600795 0,07522484 ! Notch signaling pathway GO:0007219 96 48 1,000 0,01600795 0,0750782 ! cellular component disassembly GO:0022411 86 48 1,000 0,01600795 0,07493214 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01600795 0,07478664 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01600795 0,0746417 ! peptide metabolic process GO:0006518 76 49 1,000 0,0166458 0,07746574 ! response to temperature stimulus GO:0009266 76 49 1,000 0,0166458 0,0773162 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,0166458 0,07716722 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,0166458 0,07701883 GO:0019724|B cell mediated immunity, ! neuromuscular process GO:0050905 99 50 1,000 0,01729436 0,07986609 ! histone modification GO:0016570 91 50 1,000 0,01729436 0,07971309 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,01729436 0,07956067 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01729436 0,07940884 ! positive regulation of binding GO:0051099 78 51 1,000 0,01795354 0,08227851 ! viral infectious cycle GO:0019058 99 51 1,000 0,01795354 0,08212209 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01795354 0,08196626 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,01795354 0,08181102 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,01795354 0,08165636 ! vesicle organization GO:0016050 107 51 1,000 0,01795354 0,0815023 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,01795354 0,08134881 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! covalent chromatin modification GO:0016569 101 52 1,000 0,01862324 0,08422466 ! cell maturation GO:0048469 100 53 1,000 0,01930337 0,0871368 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01992887 0,08979186 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01992887 0,08962402 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01992887 0,08945681 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01992887 0,08929023 ! neuron fate determination GO:0048664 7 5 0,000 0,01992887 0,08912426 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01992887 0,08895891 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01992887 0,08879417 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01992887 0,08863004 ! polyol transport GO:0015791 12 5 0,000 0,01992887 0,08846652 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01992887 0,08830359 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01992887 0,08814127 ! response to superoxide GO:0000303 10 5 0,000 0,01992887 0,08797954 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01992887 0,08781841 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01992887 0,08765786 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01992887 0,0874979 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01992887 0,08733853 ! female meiosis GO:0007143 7 5 0,000 0,01992887 0,08717973 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01992887 0,08702151 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01992887 0,08686386 ! cobalt ion transport GO:0006824 11 5 0,000 0,01992887 0,08670678 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01992887 0,08655027 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01992887 0,08639433 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01992887 0,08623894 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01992887 0,08608411 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01992887 0,08592984 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01992887 0,08577612 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01992887 0,08562295 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01992887 0,08547032 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01992887 0,08531824 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01992887 0,0851667 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01992887 0,08501569 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01992887 0,08486522 ! negative chemotaxis GO:0050919 14 5 0,000 0,01992887 0,08471529 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01992887 0,08456588 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01992887 0,08441699 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01992887 0,08426863 ! behavioral response to pain GO:0048266 9 5 0,000 0,01992887 0,08412079 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01992887 0,08397347 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01992887 0,08382666 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01992887 0,08368037 ! micturition GO:0060073 9 5 0,000 0,01992887 0,08353458 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01992887 0,08338931 ! copulation GO:0007620 9 5 0,000 0,01992887 0,08324453 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01992887 0,08310026 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01992887 0,08295649 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01992887 0,08281322 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01992887 0,08267043 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01992887 0,08252814 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01992887 0,08238634 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01992887 0,08224503 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01992887 0,0821042 ! grooming behavior GO:0007625 6 5 0,000 0,01992887 0,08196385 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01992887 0,08182398 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01992887 0,08168459 ! response to protozoan GO:0001562 10 5 0,000 0,01992887 0,08154567 ! lymph vessel development GO:0001945 10 5 0,000 0,01992887 0,08140722 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01992887 0,08126924 ! endochondral ossification GO:0001958 16 5 0,000 0,01992887 0,08113173 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01992887 0,08099468 ! parathyroid gland development GO:0060017 13 5 0,000 0,01992887 0,0808581 ! anagen GO:0042640 6 5 0,000 0,01992887 0,08072197 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01992887 0,08058631 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01992887 0,08045109 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01992887 0,08031633 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01992887 0,08018203 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01992887 0,08004817 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01992887 0,07991475 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01992887 0,07978178 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01992887 0,07964926 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01992887 0,07951717 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01992887 0,07938552 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01992887 0,0792543 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01992887 0,07912352 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01992887 0,07899317 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01992887 0,07886324 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01992887 0,07873375 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01992887 0,07860467 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01992887 0,07847603 ! histidine catabolic process GO:0006548 6 5 0,000 0,01992887 0,0783478 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01992887 0,07821999 ! microvillus organization GO:0032528 7 5 0,000 0,01992887 0,07809259 GO:0030033|microvillus assembly, ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01992887 0,07796561 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01992887 0,07783904 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01992887 0,07771289 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01992887 0,07758714 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01992887 0,0774618 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01992887 0,07733686 ! polyol catabolic process GO:0046174 7 5 0,000 0,01992887 0,07721232 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01992887 0,07708819 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01992887 0,07696445 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01992887 0,07684111 ! muscle cell migration GO:0014812 8 5 0,000 0,01992887 0,07671816 ! mitochondrial fission GO:0000266 8 5 0,000 0,01992887 0,07659561 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01992887 0,07647345 ! mRNA transcription GO:0009299 9 5 0,000 0,01992887 0,07635167 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01992887 0,07623029 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01992887 0,07610929 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01992887 0,07598867 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01992887 0,07586844 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01992887 0,07574858 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01992887 0,0756291 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01992887 0,07551 ! response to food GO:0032094 6 5 0,000 0,01992887 0,07539128 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01992887 0,07527292 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01992887 0,07515494 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01992887 0,07503733 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01992887 0,07492008 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01992887 0,0748032 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,01992887 0,07468668 ! forebrain neuron development GO:0021884 13 5 0,000 0,01992887 0,07457053 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01992887 0,07445474 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01992887 0,0743393 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01992887 0,07422423 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01992887 0,07410951 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01992887 0,07399514 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01992887 0,07388113 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01992887 0,07376746 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01992887 0,07365415 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01992887 0,07354118 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01992887 0,07342856 ! basic amino acid transport GO:0015802 11 5 0,000 0,01992887 0,07331629 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01992887 0,07320435 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01992887 0,07309276 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01992887 0,07298151 ! depyrimidination GO:0045008 10 5 0,000 0,01992887 0,0728706 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01992887 0,07276002 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01992887 0,07264978 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01992887 0,07253987 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01992887 0,07243029 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01992887 0,07232104 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01992887 0,07221213 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01992887 0,07210354 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01992887 0,07199527 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01992887 0,07188733 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01992887 0,07177972 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01992887 0,07167242 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01992887 0,07156545 ! response to arsenic GO:0046685 10 5 0,000 0,01992887 0,0714588 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01992887 0,07135246 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01992887 0,07124644 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01992887 0,07114073 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01992887 0,07103534 ! response to cadmium ion GO:0046686 7 5 0,000 0,01992887 0,07093025 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01992887 0,07082548 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01992887 0,07072102 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01992887 0,07061687 ! decidualization GO:0046697 11 5 0,000 0,01992887 0,07051302 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01992887 0,07040947 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01992887 0,07030623 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01992887 0,0702033 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01992887 0,07010066 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01992887 0,06999832 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01992887 0,06989629 ! neural tube patterning GO:0021532 7 5 0,000 0,01992887 0,06979454 ! embryonic cleavage GO:0040016 6 5 0,000 0,01992887 0,0696931 ! peroxisome fission GO:0016559 5 5 0,000 0,01992887 0,06959195 ! histone demethylation GO:0016577 10 5 0,000 0,01992887 0,06949109 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01992887 0,06939052 ! mitotic recombination GO:0006312 9 5 0,000 0,01992887 0,06929025 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01992887 0,06919026 ! metaphase plate congression GO:0051310 7 5 0,000 0,01992887 0,06909056 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01992887 0,06899115 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01992887 0,06889203 ! enteric nervous system development GO:0048484 8 5 0,000 0,01992887 0,06879319 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01992887 0,06869463 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01992887 0,06859635 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01992887 0,06849836 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01992887 0,06840064 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01992887 0,06830321 ! plasminogen activation GO:0031639 5 5 0,000 0,01992887 0,06820605 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01992887 0,06810916 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01992887 0,06801256 ! metaphase GO:0051323 8 5 0,000 0,01992887 0,06791622 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01992887 0,06782016 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01992887 0,06772437 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01992887 0,06762885 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01992887 0,06753359 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01992887 0,06743861 GO:0015991|ATP hydrolysis coupled proton transport, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01992887 0,06734389 ! response to redox state GO:0051775 5 5 0,000 0,01992887 0,06724944 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01992887 0,06715525 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01992887 0,06706133 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01992887 0,06696767 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01992887 0,06687427 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01992887 0,06678113 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01992887 0,06668825 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01992887 0,06659563 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01992887 0,06650326 ! striatum development GO:0021756 9 5 0,000 0,01992887 0,06641115 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01992887 0,0663193 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01992887 0,0662277 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01992887 0,06613635 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01992887 0,06604525 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01992887 0,0659544 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01992887 0,06586381 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01992887 0,06577346 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01992887 0,06568336 ! neuroprotection GO:0043526 6 5 0,000 0,01992887 0,0655935 ! neural plate development GO:0001840 8 5 0,000 0,01992887 0,0655039 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01992887 0,06541453 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01992887 0,06532541 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01992887 0,06523653 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01992887 0,0651479 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01992887 0,0650595 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01992887 0,06497134 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01992887 0,06488343 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01992887 0,06479575 ! spindle assembly GO:0051225 6 5 0,000 0,01992887 0,0647083 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01992887 0,06462109 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01992887 0,06453412 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01992887 0,06444738 ! drug metabolic process GO:0017144 6 5 0,000 0,01992887 0,06436087 ! phospholipid scrambling GO:0017121 8 5 0,000 0,01992887 0,0642746 ! organ regeneration GO:0031100 7 5 0,000 0,01992887 0,06418856 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01992887 0,06410274 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01992887 0,06401716 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01992887 0,0639318 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 1,000 0,01999384 0,06405483 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02069455 0,06621154 ! gastrulation GO:0007369 112 55 1,000 0,02069455 0,06612361 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,02069455 0,06603592 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02140541 0,06821379 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,02212633 0,07041791 ! lipid modification GO:0030258 97 57 1,000 0,02212633 0,07032489 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02212633 0,07023211 ! adult behavior GO:0030534 99 58 1,000 0,02285722 0,07245647 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,02359798 0,07470624 ! DNA catabolic process GO:0006308 86 59 1,000 0,02359798 0,07460807 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02386712 0,07535995 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02386712 0,07526118 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02386712 0,07516267 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02386712 0,07506442 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02386712 0,07496643 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02386712 0,07486869 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02386712 0,0747712 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02386712 0,07467397 ! sleep GO:0030431 13 6 0,000 0,02386712 0,07457699 ! response to oxygen radical GO:0000305 11 6 0,000 0,02386712 0,07448026 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02386712 0,07438379 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02386712 0,07428756 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02386712 0,07419158 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02386712 0,07409585 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02386712 0,07400036 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02386712 0,07390513 ! forebrain regionalization GO:0021871 8 6 0,000 0,02386712 0,07381013 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02386712 0,07371538 ! male meiosis GO:0007140 7 6 0,000 0,02386712 0,07362088 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02386712 0,07352661 ! response to zinc ion GO:0010043 9 6 0,000 0,02386712 0,07343259 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02386712 0,0733388 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02386712 0,07324526 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02386712 0,07315195 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02386712 0,07305888 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02386712 0,07296605 ! malate metabolic process GO:0006108 11 6 0,000 0,02386712 0,07287346 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02386712 0,07278109 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02386712 0,07268897 ! protein refolding GO:0042026 15 6 0,000 0,02386712 0,07259707 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02386712 0,07250541 ! opsonization GO:0008228 8 6 0,000 0,02386712 0,07241398 ! mating behavior GO:0007617 7 6 0,000 0,02386712 0,07232277 ! neuron remodeling GO:0016322 15 6 0,000 0,02386712 0,0722318 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02386712 0,07214106 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02386712 0,07205054 ! equilibrioception GO:0050957 14 6 0,000 0,02386712 0,07196025 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02386712 0,07187019 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02386712 0,07178035 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02386712 0,07169074 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02386712 0,07160135 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02386712 0,07151218 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02386712 0,07142324 ! toxin metabolic process GO:0009404 11 6 0,000 0,02386712 0,07133451 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02386712 0,07124601 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02386712 0,07115772 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02386712 0,07106966 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02386712 0,07098181 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02386712 0,07089418 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02386712 0,07080676 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02386712 0,07071956 ! thymic T cell selection GO:0045061 12 6 0,000 0,02386712 0,07063257 ! protein lipoylation GO:0009249 10 6 0,000 0,02386712 0,0705458 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02386712 0,07045924 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02386712 0,0703729 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02386712 0,07028676 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02386712 0,07020083 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02386712 0,07011512 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! adenohypophysis development GO:0021984 10 6 0,000 0,02386712 0,07002961 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02386712 0,06994432 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02386712 0,06985922 ! hyperosmotic response GO:0006972 9 6 0,000 0,02386712 0,06977434 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02386712 0,06968966 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02386712 0,06960519 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02386712 0,06952092 ! urea metabolic process GO:0019627 7 6 0,000 0,02386712 0,06943686 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02386712 0,069353 ! neutrophil activation GO:0042119 8 6 0,000 0,02386712 0,06926934 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02386712 0,06918588 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02386712 0,06910263 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02386712 0,06901957 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02386712 0,06893671 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02386712 0,06885406 ! neuron apoptosis GO:0051402 9 6 0,000 0,02386712 0,0687716 ! nucleoside salvage GO:0043174 9 6 0,000 0,02386712 0,06868933 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02386712 0,06860727 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02386712 0,0685254 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02386712 0,06844372 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02386712 0,06836224 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02386712 0,06828095 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02386712 0,06819986 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02386712 0,06811896 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02386712 0,06803825 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02386712 0,06795773 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02386712 0,0678774 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02386712 0,06779726 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02386712 0,06771731 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02386712 0,06763755 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02386712 0,06755798 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02386712 0,06747859 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02386712 0,06739939 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02386712 0,06732038 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02386712 0,06724155 ! response to UV-C GO:0010225 11 6 0,000 0,02386712 0,0671629 ! astrocyte development GO:0014002 15 6 0,000 0,02386712 0,06708444 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02386712 0,06700616 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02386712 0,06692807 ! interaction with symbiont GO:0051702 13 6 0,000 0,02386712 0,06685015 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02386712 0,06677242 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02386712 0,06669487 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02386712 0,0666175 ! response to copper ion GO:0046688 10 6 0,000 0,02386712 0,0665403 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02386712 0,06646329 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02386712 0,06638645 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02386712 0,0663098 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02386712 0,06623331 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02386712 0,06615701 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02386712 0,06608088 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02386712 0,06600492 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02386712 0,06592914 ! hair follicle maturation GO:0048820 7 6 0,000 0,02386712 0,06585354 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02386712 0,0657781 ! Schwann cell development GO:0014044 15 6 0,000 0,02386712 0,06570284 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02386712 0,06562775 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02386712 0,06555283 ! subpallium development GO:0021544 10 6 0,000 0,02386712 0,06547809 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02386712 0,06540351 ! histone ubiquitination GO:0016574 8 6 0,000 0,02386712 0,0653291 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02386712 0,06525487 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02386712 0,0651808 ! G2 phase GO:0051319 16 6 0,000 0,02386712 0,0651069 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02386712 0,06503316 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02386712 0,0649596 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02386712 0,0648862 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02386712 0,06481296 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02386712 0,06473989 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02386712 0,06466699 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02386712 0,06459424 ! receptor internalization GO:0031623 10 6 0,000 0,02386712 0,06452167 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02386712 0,06444925 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02386712 0,064377 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,02386712 0,06430491 ! protein destabilization GO:0031648 9 6 0,000 0,02386712 0,06423298 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02386712 0,06416121 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02386712 0,0640896 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02386712 0,06401815 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02386712 0,06394686 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02386712 0,06387573 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02386712 0,06380476 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02386712 0,06373394 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02386712 0,06366328 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02386712 0,06359278 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02386712 0,06352244 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02386712 0,06345225 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02386712 0,06338221 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02386712 0,06331233 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02386712 0,0632426 ! catecholamine transport GO:0051937 9 6 0,000 0,02386712 0,06317303 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02386712 0,06310361 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02386712 0,06303434 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02386712 0,06296522 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02386712 0,06289626 ! maternal placenta development GO:0001893 12 6 0,000 0,02386712 0,06282744 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02386712 0,06275878 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02386712 0,06269027 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02386712 0,0626219 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02386712 0,06255369 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02386712 0,06248562 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02386712 0,0624177 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02386712 0,06234993 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,02434854 0,06353859 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,02434854 0,06346975 ! mesoderm development GO:0007498 119 61 1,000 0,02510879 0,06538069 ! gonad development GO:0008406 98 62 1,000 0,02587866 0,06731249 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,02744687 0,07131443 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,02744687 0,0712375 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,02744687 0,07116074 GO:0048609|reproductive process in a multicellular organism, ! tRNA transcription GO:0009304 14 7 0,000 0,02778967 0,07197196 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02778967 0,07189457 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02778967 0,07181735 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02778967 0,07174029 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02778967 0,0716634 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02778967 0,07158667 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02778967 0,07151011 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02778967 0,07143371 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02778967 0,07135747 ! prostate gland development GO:0030850 13 7 0,000 0,02778967 0,0712814 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02778967 0,07120549 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02778967 0,07112974 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02778967 0,07105415 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02778967 0,07097872 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02778967 0,07090345 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02778967 0,07082834 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02778967 0,07075339 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02778967 0,0706786 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02778967 0,07060396 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02778967 0,07052949 ! glycolipid transport GO:0046836 10 7 0,000 0,02778967 0,07045517 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02778967 0,070381 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02778967 0,070307 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02778967 0,07023314 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02778967 0,07015945 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02778967 0,0700859 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02778967 0,07001252 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02778967 0,06993928 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02778967 0,0698662 ! mRNA stabilization GO:0048255 18 7 0,000 0,02778967 0,06979327 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02778967 0,06972049 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02778967 0,06964787 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02778967 0,06957539 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02778967 0,06950307 ! lipoprotein transport GO:0042953 14 7 0,000 0,02778967 0,0694309 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02778967 0,06935887 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02778967 0,069287 ! rhythmic behavior GO:0007622 15 7 0,000 0,02778967 0,06921527 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02778967 0,06914369 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02778967 0,06907226 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02778967 0,06900098 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02778967 0,06892985 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02778967 0,06885886 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02778967 0,06878802 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02778967 0,06871732 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02778967 0,06864677 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02778967 0,06857636 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02778967 0,0685061 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02778967 0,06843598 ! spinal cord patterning GO:0021511 13 7 0,000 0,02778967 0,068366 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02778967 0,06829617 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02778967 0,06822648 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02778967 0,06815693 ! adrenal gland development GO:0030325 17 7 0,000 0,02778967 0,06808753 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02778967 0,06801826 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02778967 0,06794914 ! ovulation GO:0030728 9 7 0,000 0,02778967 0,06788015 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02778967 0,06781131 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02778967 0,06774261 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline biosynthetic process GO:0006561 10 7 0,000 0,02778967 0,06767404 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02778967 0,06760561 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02778967 0,06753733 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02778967 0,06746917 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02778967 0,06740116 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02778967 0,06733329 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02778967 0,06726555 ! galactose metabolic process GO:0006012 13 7 0,000 0,02778967 0,06719794 ! vesicle fusion GO:0006906 17 7 0,000 0,02778967 0,06713047 ! response to dietary excess GO:0002021 8 7 0,000 0,02778967 0,06706314 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02778967 0,06699594 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02778967 0,06692888 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02778967 0,06686195 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02778967 0,06679516 ! purine salvage GO:0043101 10 7 0,000 0,02778967 0,0667285 ! nucleoside transport GO:0015858 8 7 0,000 0,02778967 0,06666197 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02778967 0,06659557 ! parturition GO:0007567 14 7 0,000 0,02778967 0,06652931 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02778967 0,06646317 ! rRNA modification GO:0000154 14 7 0,000 0,02778967 0,06639717 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02778967 0,0663313 ! spindle checkpoint GO:0031577 15 7 0,000 0,02778967 0,06626556 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02778967 0,06619995 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02778967 0,06613447 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02778967 0,06606912 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02778967 0,0660039 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02778967 0,06593881 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02778967 0,06587384 ! fibrinolysis GO:0042730 10 7 0,000 0,02778967 0,06580901 ! eating behavior GO:0042755 7 7 0,000 0,02778967 0,0657443 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02778967 0,06567972 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02778967 0,06561526 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02778967 0,06555093 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02778967 0,06548673 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02778967 0,06542265 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02778967 0,0653587 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02778967 0,06529488 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02778967 0,06523117 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02778967 0,06516759 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02778967 0,06510414 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02778967 0,06504081 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02778967 0,0649776 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02778967 0,06491452 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02778967 0,06485155 ! regulation of meiosis GO:0040020 12 7 0,000 0,02778967 0,06478871 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02778967 0,06472599 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02778967 0,0646634 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02778967 0,06460092 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02778967 0,06453856 ! transcription termination GO:0006353 13 7 0,000 0,02778967 0,06447633 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02778967 0,06441421 ! anaphase GO:0051322 17 7 0,000 0,02778967 0,06435222 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02778967 0,06429034 ! axonal fasciculation GO:0007413 18 7 0,000 0,02778967 0,06422858 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02778967 0,06416694 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02778967 0,06410542 ! diuresis GO:0030146 12 7 0,000 0,02778967 0,06404402 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02778967 0,06398273 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02778967 0,06392156 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02778967 0,06386051 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02778967 0,06379957 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02778967 0,06373875 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02778967 0,06367805 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02778967 0,06361746 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02778967 0,06355699 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02778967 0,06349663 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02778967 0,06343639 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02778967 0,06337626 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,02778967 0,06331624 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02778967 0,06325634 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02778967 0,06319655 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02778967 0,06313688 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02778967 0,06307731 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02778967 0,06301786 ! adult feeding behavior GO:0008343 9 7 0,000 0,02778967 0,06295852 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02778967 0,0628993 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02778967 0,06284018 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02778967 0,06278118 ! muscle adaptation GO:0043500 14 7 0,000 0,02778967 0,06272228 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02778967 0,0626635 ! retina homeostasis GO:0001895 12 7 0,000 0,02778967 0,06260482 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02778967 0,06254626 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02778967 0,06248781 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02778967 0,06242946 ! protein prenylation GO:0018342 18 7 0,000 0,02778967 0,06237122 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02778967 0,0623131 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02778967 0,06225508 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02778967 0,06219716 ! germ cell development GO:0007281 118 65 1,000 0,02824504 0,06315759 ! actin filament organization GO:0007015 148 66 1,000 0,02905247 0,06490273 ! secondary metabolic process GO:0019748 116 66 1,000 0,02905247 0,06484253 ! developmental maturation GO:0021700 116 66 1,000 0,02905247 0,06478243 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,02986908 0,06654167 ! chromosome segregation GO:0007059 113 67 1,000 0,02986908 0,06648011 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,02986908 0,06641867 ! adaptive immune response GO:0002250 119 67 1,000 0,02986908 0,06635734 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,02986908 0,06629613 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0316966 0,07028757 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0316966 0,07022284 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 0,000 0,0316966 0,07015824 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0316966 0,07009376 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0316966 0,07002939 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0316966 0,06996515 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0316966 0,06990102 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0316966 0,069837 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0316966 0,06977311 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0316966 0,06970933 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0316966 0,06964567 ! meiotic prophase I GO:0007128 13 8 0,000 0,0316966 0,06958212 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0316966 0,0695187 ! oligopeptide transport GO:0006857 15 8 0,000 0,0316966 0,06945538 ! UTP metabolic process GO:0046051 8 8 0,000 0,0316966 0,06939218 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0316966 0,0693291 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0316966 0,06926613 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0316966 0,06920327 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0316966 0,06914053 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0316966 0,06907791 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0316966 0,06901539 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0316966 0,06895299 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0316966 0,0688907 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0316966 0,06882853 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0316966 0,06876646 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0316966 0,06870451 ! reflex GO:0060004 16 8 0,000 0,0316966 0,06864267 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0316966 0,06858094 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0316966 0,06851933 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0316966 0,06845782 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0316966 0,06839642 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0316966 0,06833513 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0316966 0,06827396 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0316966 0,06821289 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0316966 0,06815193 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0316966 0,06809108 ! histidine metabolic process GO:0006547 16 8 0,000 0,0316966 0,06803034 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0316966 0,0679697 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0316966 0,06790918 ! glycine catabolic process GO:0006546 13 8 0,000 0,0316966 0,06784876 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0316966 0,06778845 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0316966 0,06772825 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0316966 0,06766815 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0316966 0,06760816 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0316966 0,06754828 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0316966 0,0674885 ! macrophage activation GO:0042116 12 8 0,000 0,0316966 0,06742883 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0316966 0,06736927 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0316966 0,0673098 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0316966 0,06725045 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0316966 0,0671912 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0316966 0,06713205 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0316966 0,06707301 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0316966 0,06701407 ! osteoblast development GO:0002076 16 8 0,000 0,0316966 0,06695523 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0316966 0,0668965 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0316966 0,06683787 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0316966 0,06677934 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0316966 0,06672092 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0316966 0,0666626 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0316966 0,06660437 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0316966 0,06654626 ! intermediate filament organization GO:0045109 12 8 0,000 0,0316966 0,06648824 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0316966 0,06643032 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0316966 0,06637251 ! cellular extravasation GO:0045123 12 8 0,000 0,0316966 0,06631479 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0316966 0,06625718 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0316966 0,06619966 ! response to antibiotic GO:0046677 11 8 0,000 0,0316966 0,06614225 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0316966 0,06608493 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0316966 0,06602771 ! DNA topological change GO:0006265 12 8 0,000 0,0316966 0,0659706 ! response to tropane GO:0014073 15 8 0,000 0,0316966 0,06591358 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0316966 0,06585666 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,0316966 0,06579984 ! melanosome transport GO:0032402 13 8 0,000 0,0316966 0,06574311 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0316966 0,06568648 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0316966 0,06562996 ! mast cell activation GO:0045576 14 8 0,000 0,0316966 0,06557352 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0316966 0,06551719 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0316966 0,06546095 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0316966 0,06540481 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0316966 0,06534877 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0316966 0,06529282 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0316966 0,06523696 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0316966 0,0651812 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0316966 0,06512554 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0316966 0,06506997 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0316966 0,0650145 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0316966 0,06495912 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0316966 0,06490384 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0316966 0,06484865 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0316966 0,06479355 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0316966 0,06473855 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0316966 0,06468364 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0316966 0,06462882 ! hormone catabolic process GO:0042447 17 8 0,000 0,0316966 0,0645741 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0316966 0,06451947 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0316966 0,06446493 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0316966 0,06441048 ! ATP catabolic process GO:0006200 11 8 0,000 0,0316966 0,06435613 ! blastocyst growth GO:0001832 19 8 0,000 0,0316966 0,06430186 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0316966 0,06424769 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0316966 0,06419361 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0316966 0,06413962 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0316966 0,06408572 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0316966 0,06403191 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0316966 0,0639782 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0316966 0,06392457 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0316966 0,06387103 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0316966 0,06381758 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0316966 0,06376422 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0316966 0,06371095 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0316966 0,06365777 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0316966 0,06360468 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0316966 0,06355167 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0316966 0,06349876 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0316966 0,06344593 ! reproductive structure development GO:0048608 113 71 1,000 0,03322556 0,06645112 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,03322556 0,06639593 ! acute inflammatory response GO:0002526 113 72 1,000 0,03408678 0,0680604 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03408678 0,06800397 ! axon extension GO:0048675 15 9 0,000 0,03558795 0,07094002 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03558795 0,07088129 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03558795 0,07082266 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03558795 0,07076413 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03558795 0,0707057 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03558795 0,07064736 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03558795 0,07058912 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03558795 0,07053097 ! phosphate transport GO:0006817 19 9 0,000 0,03558795 0,07047292 ! reproductive behavior GO:0019098 19 9 0,000 0,03558795 0,07041497 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03558795 0,07035711 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03558795 0,07029934 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03558795 0,07024167 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03558795 0,0701841 ! GTP metabolic process GO:0046039 9 9 0,000 0,03558795 0,07012662 ! RNA methylation GO:0001510 15 9 0,000 0,03558795 0,07006923 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03558795 0,07001194 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03558795 0,06995474 ! artery development GO:0060840 24 9 0,000 0,03558795 0,06989763 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03558795 0,06984062 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03558795 0,0697837 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03558795 0,06972687 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03558795 0,06967014 ! chemosensory behavior GO:0007635 20 9 0,000 0,03558795 0,0696135 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03558795 0,06955695 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03558795 0,06950049 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03558795 0,06944412 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03558795 0,06938785 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03558795 0,06933166 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03558795 0,06927557 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03558795 0,06921956 ! protein targeting to ER GO:0045047 22 9 0,000 0,03558795 0,06916365 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03558795 0,06910783 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03558795 0,0690521 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03558795 0,06899646 ! endosome organization GO:0007032 17 9 0,000 0,03558795 0,0689409 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03558795 0,06888544 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03558795 0,06883007 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03558795 0,06877478 ! mannose metabolic process GO:0006013 13 9 0,000 0,03558795 0,06871958 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03558795 0,06866448 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03558795 0,06860946 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03558795 0,06855452 ! receptor clustering GO:0043113 18 9 0,000 0,03558795 0,06849968 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03558795 0,06844493 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03558795 0,06839026 ! ruffle organization GO:0031529 15 9 0,000 0,03558795 0,06833568 ! retinol metabolic process GO:0042572 18 9 0,000 0,03558795 0,06828118 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03558795 0,06822677 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03558795 0,06817245 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03558795 0,06811822 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03558795 0,06806407 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03558795 0,06801001 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03558795 0,06795603 ! segment specification GO:0007379 13 9 0,000 0,03558795 0,06790214 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03558795 0,06784834 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03558795 0,06779462 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03558795 0,06774098 ! response to amine stimulus GO:0014075 13 9 0,000 0,03558795 0,06768743 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03558795 0,06763397 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03558795 0,06758059 ! erythrocyte development GO:0048821 15 9 0,000 0,03558795 0,06752729 ! gas homeostasis GO:0033483 16 9 0,000 0,03558795 0,06747408 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03558795 0,06742095 ! renal water homeostasis GO:0003091 14 9 0,000 0,03558795 0,0673679 ! postreplication repair GO:0006301 22 9 0,000 0,03558795 0,06731494 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03558795 0,06726206 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03558795 0,06720926 ! icosanoid secretion GO:0032309 15 9 0,000 0,03558795 0,06715655 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03558795 0,06710392 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03558795 0,06705137 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03558795 0,06699891 ! regulation of cell division GO:0051302 15 9 0,000 0,03558795 0,06694652 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03558795 0,06689422 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03558795 0,066842 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03558795 0,06678986 ! sterol catabolic process GO:0016127 11 9 0,000 0,03558795 0,0667378 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03558795 0,06668583 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03558795 0,06663393 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03558795 0,06658212 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03558795 0,06653038 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03558795 0,06647873 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03558795 0,06642715 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03558795 0,06637566 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03558795 0,06632425 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03558795 0,06627291 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03558795 0,06622166 ! purine base metabolic process GO:0006144 21 9 0,000 0,03558795 0,06617048 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03558795 0,06611938 ! pigment granule transport GO:0051904 17 9 0,000 0,03558795 0,06606837 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03558795 0,06601743 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03558795 0,06596656 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03558795 0,06591578 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03558795 0,06586508 ! mitochondrion localization GO:0051646 15 9 0,000 0,03558795 0,06581445 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03583513 0,06622068 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,03583513 0,06616986 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,03672211 0,06775568 ! rhythmic process GO:0048511 128 75 1,000 0,03672211 0,06770376 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,03761752 0,06930149 ! regulation of catabolic process GO:0009894 161 76 1,000 0,03761752 0,06924847 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,03852127 0,07085793 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,03943328 0,07248012 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03946379 0,07248082 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03946379 0,07242554 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03946379 0,07237033 ! synapsis GO:0007129 13 10 0,000 0,03946379 0,07231522 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03946379 0,07226018 ! N-glycan processing GO:0006491 20 10 0,000 0,03946379 0,07220523 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03946379 0,07215036 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03946379 0,07209558 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03946379 0,07204088 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03946379 0,07198626 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03946379 0,07193173 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03946379 0,07187727 ! androgen metabolic process GO:0008209 17 10 0,000 0,03946379 0,0718229 ! phospholipid efflux GO:0033700 16 10 0,000 0,03946379 0,07176862 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03946379 0,07171441 ! lung alveolus development GO:0048286 26 10 0,000 0,03946379 0,07166029 ! pathogenesis GO:0009405 13 10 0,000 0,03946379 0,07160624 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03946379 0,07155228 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03946379 0,0714984 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03946379 0,0714446 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03946379 0,07139089 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,03946379 0,07133725 ! endoderm development GO:0007492 16 10 0,000 0,03946379 0,07128369 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03946379 0,07123022 ! arginine catabolic process GO:0006527 13 10 0,000 0,03946379 0,07117682 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03946379 0,0711235 ! proline metabolic process GO:0006560 13 10 0,000 0,03946379 0,07107027 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03946379 0,07101711 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03946379 0,07096403 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03946379 0,07091104 ! V(D)J recombination GO:0033151 28 10 0,000 0,03946379 0,07085812 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03946379 0,07080528 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03946379 0,07075252 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03946379 0,07069983 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03946379 0,07064723 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03946379 0,0705947 ! multicellular organism growth GO:0035264 18 10 0,000 0,03946379 0,07054226 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03946379 0,07048989 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03946379 0,07043759 ! epithelial cell development GO:0002064 20 10 0,000 0,03946379 0,07038538 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03946379 0,07033324 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03946379 0,07028118 ! macroautophagy GO:0016236 17 10 0,000 0,03946379 0,0702292 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03946379 0,07017729 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03946379 0,07012546 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03946379 0,07007371 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03946379 0,07002203 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03946379 0,06997043 ! brain morphogenesis GO:0048854 23 10 0,000 0,03946379 0,06991891 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03946379 0,06986746 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03946379 0,06981609 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03946379 0,06976479 ! response to dsRNA GO:0043331 20 10 0,000 0,03946379 0,06971357 ! DNA ligation GO:0006266 19 10 0,000 0,03946379 0,06966242 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03946379 0,06961135 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03946379 0,06956035 ! melanosome localization GO:0032400 16 10 0,000 0,03946379 0,06950943 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03946379 0,06945858 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03946379 0,06940781 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,03946379 0,06935711 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03946379 0,06930648 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03946379 0,06925593 ! mRNA cleavage GO:0006379 17 10 0,000 0,03946379 0,06920545 ! protein sumoylation GO:0016925 15 10 0,000 0,03946379 0,06915505 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03946379 0,06910471 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03946379 0,06905446 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03946379 0,06900427 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03946379 0,06895416 ! prophase GO:0051324 15 10 0,000 0,03946379 0,06890412 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03946379 0,06885415 ! apical protein localization GO:0045176 15 10 0,000 0,03946379 0,06880426 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03946379 0,06875444 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03946379 0,06870469 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03946379 0,06865501 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03946379 0,0686054 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03946379 0,06855587 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03946379 0,06850641 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03946379 0,06845701 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03946379 0,06840769 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03946379 0,06835844 ! detection of calcium ion GO:0005513 23 10 0,000 0,03946379 0,06830926 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03946379 0,06826016 ! blastocyst formation GO:0001825 17 10 0,000 0,03946379 0,06821112 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03946379 0,06816215 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03946379 0,06811326 ! activation of innate immune response GO:0002218 12 10 0,000 0,03946379 0,06806443 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03946379 0,06801567 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03946379 0,06796698 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03946379 0,06791837 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03946379 0,06786982 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03946379 0,06782134 ! localization within membrane GO:0051668 20 10 0,000 0,03946379 0,06777293 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,04221811 0,07245134 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,04221811 0,0723997 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04332418 0,07424358 ! respiratory burst GO:0045730 17 11 0,000 0,04332418 0,07419074 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04332418 0,07413797 ! neuron fate specification GO:0048665 17 11 0,000 0,04332418 0,07408528 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04332418 0,07403266 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04332418 0,07398012 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04332418 0,07392765 ! thyroid gland development GO:0030878 26 11 0,000 0,04332418 0,07387526 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 0,000 0,04332418 0,07382294 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04332418 0,07377069 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04332418 0,07371852 ! response to pain GO:0048265 24 11 0,000 0,04332418 0,07366642 ! T cell proliferation GO:0042098 26 11 0,000 0,04332418 0,0736144 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04332418 0,07356245 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04332418 0,07351057 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04332418 0,07345876 ! bone resorption GO:0045453 16 11 0,000 0,04332418 0,07340703 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04332418 0,07335537 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04332418 0,07330379 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04332418 0,07325227 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04332418 0,07320083 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04332418 0,07314946 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04332418 0,07309817 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04332418 0,07304694 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04332418 0,07299579 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04332418 0,07294471 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04332418 0,0728937 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04332418 0,07284276 ! UV protection GO:0009650 19 11 0,000 0,04332418 0,07279189 ! adult heart development GO:0007512 14 11 0,000 0,04332418 0,07274109 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04332418 0,07269037 ! temperature homeostasis GO:0001659 17 11 0,000 0,04332418 0,07263971 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04332418 0,07258913 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04332418 0,07253861 ! regulation of organ growth GO:0046620 13 11 0,000 0,04332418 0,07248817 ! pigment granule localization GO:0051875 20 11 0,000 0,04332418 0,07243779 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04332418 0,07238749 ! vasoconstriction GO:0042310 18 11 0,000 0,04332418 0,07233726 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04332418 0,07228709 ! embryonic axis specification GO:0000578 18 11 0,000 0,04332418 0,072237 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04332418 0,07218697 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04332418 0,07213701 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04332418 0,07208713 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04332418 0,07203731 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04332418 0,07198756 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04332418 0,07193788 ! zymogen activation GO:0031638 15 11 0,000 0,04332418 0,07188827 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04332418 0,07183872 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04332418 0,07178925 ! nucleosome positioning GO:0016584 15 11 0,000 0,04332418 0,07173984 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04332418 0,0716905 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04332418 0,07164123 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04332418 0,07159202 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04332418 0,07154289 ! acid secretion GO:0046717 18 11 0,000 0,04332418 0,07149382 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04332418 0,07144482 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04332418 0,07139588 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04332418 0,07134701 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04332418 0,07129821 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04332418 0,07124948 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,04332418 0,07120081 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04332418 0,07115221 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04332418 0,07110367 ! germ cell migration GO:0008354 25 11 0,000 0,04332418 0,0710552 ! embryonic gut development GO:0048566 15 11 0,000 0,04332418 0,0710068 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04332418 0,07095847 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04332418 0,07091019 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04332418 0,07086199 ! defense response to fungus GO:0050832 13 11 0,000 0,04332418 0,07081385 ! developmental induction GO:0031128 19 11 0,000 0,04332418 0,07076577 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04332418 0,07071777 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04332418 0,07066982 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04332418 0,07062194 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04332418 0,07057413 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04332418 0,07052638 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04332418 0,07047869 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,04604214 0,07484958 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 1,000 0,04701743 0,07638349 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04716919 0,07657832 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04716919 0,07652668 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04716919 0,07647512 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04716919 0,07642362 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04716919 0,07637219 ! mating GO:0007618 17 12 0,000 0,04716919 0,07632083 ! protein complex disassembly GO:0043241 27 12 0,000 0,04716919 0,07626954 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04716919 0,07621832 ! hippocampus development GO:0021766 26 12 0,000 0,04716919 0,07616716 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04716919 0,07611608 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04716919 0,07606506 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04716919 0,07601411 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04716919 0,07596323 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04716919 0,07591242 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04716919 0,07586168 ! drug transport GO:0015893 16 12 0,000 0,04716919 0,075811 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04716919 0,0757604 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04716919 0,07570985 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04716919 0,07565938 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04716919 0,07560898 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04716919 0,07555864 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04716919 0,07550836 ! forebrain cell migration GO:0021885 21 12 0,000 0,04716919 0,07545816 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04716919 0,07540802 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04716919 0,07535795 ! monoamine transport GO:0015844 18 12 0,000 0,04716919 0,07530794 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04716919 0,07525801 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04716919 0,07520813 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04716919 0,07515833 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04716919 0,07510859 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04716919 0,07505891 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04716919 0,0750093 ! protein homotetramerization GO:0051289 21 12 0,000 0,04716919 0,07495976 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04716919 0,07491028 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04716919 0,07486087 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04716919 0,07481152 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04716919 0,07476223 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04716919 0,07471302 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04716919 0,07466386 ! cranial nerve development GO:0021545 20 12 0,000 0,04716919 0,07461477 ! fucose catabolic process GO:0019317 22 12 0,000 0,04716919 0,07456575 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04716919 0,07451679 ! histone methylation GO:0016571 26 12 0,000 0,04716919 0,07446789 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04716919 0,07441906 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04716919 0,0743703 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04716919 0,07432159 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04716919 0,07427295 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04716919 0,07422438 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04716919 0,07417586 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04716919 0,07412741 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04716919 0,07407903 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,04716919 0,07403071 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04716919 0,07398245 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04716919 0,07393425 ! response to cold GO:0009409 17 12 0,000 0,04716919 0,07388611 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04716919 0,07383804 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04716919 0,07379003 ! regulation of protein transport GO:0051223 154 87 1,000 0,04800029 0,07504139 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,04899064 0,07653993 ! regulation of neurological system process GO:0031644 148 88 1,000 0,04899064 0,07649026 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,04998841 0,07799747 ! sex differentiation GO:0007548 145 90 1,000 0,05099351 0,07951418 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05099887 0,07947104 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05099887 0,0794196 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05099887 0,07936823 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05099887 0,07931693 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05099887 0,07926569 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05099887 0,07921451 ! lipid localization GO:0010876 28 13 0,000 0,05099887 0,07916341 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05099887 0,07911237 ! organelle fusion GO:0048284 32 13 0,000 0,05099887 0,07906139 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05099887 0,07901048 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05099887 0,07895964 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05099887 0,07890886 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05099887 0,07885815 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05099887 0,0788075 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05099887 0,07875692 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05099887 0,0787064 ! methionine metabolic process GO:0006555 27 13 0,000 0,05099887 0,07865595 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05099887 0,07860556 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05099887 0,07855524 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05099887 0,07850498 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05099887 0,07845478 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05099887 0,07840465 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05099887 0,07835459 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05099887 0,07830458 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05099887 0,07825464 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05099887 0,07820477 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05099887 0,07815496 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05099887 0,07810521 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05099887 0,07805552 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05099887 0,0780059 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05099887 0,07795634 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05099887 0,07790685 ! ribosome assembly GO:0042255 17 13 0,000 0,05099887 0,07785741 ! regulation of monooxygenase activity GO:0032768 33 13 0,000 0,05099887 0,07780804 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05099887 0,07775873 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05099887 0,07770949 ! chromatin silencing GO:0006342 26 13 0,000 0,05099887 0,07766031 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05099887 0,07761118 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05099887 0,07756213 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05099887 0,07751313 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05099887 0,07746419 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05099887 0,07741532 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05099887 0,07736651 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05099887 0,07731776 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05099887 0,07726907 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05099887 0,07722044 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05099887 0,07717188 ! embryonic placenta development GO:0001892 23 13 0,000 0,05099887 0,07712337 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05099887 0,07707493 ! insulin secretion GO:0030073 23 13 0,000 0,05099887 0,07702654 ! actin filament polymerization GO:0030041 24 13 0,000 0,05099887 0,07697822 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05099887 0,07692996 ! acrosome reaction GO:0007340 18 13 0,000 0,05099887 0,07688176 ! response to protein stimulus GO:0051789 149 91 1,000 0,05200587 0,07835074 ! regulation of membrane potential GO:0042391 164 93 1,000 0,05405211 0,08138259 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,05405211 0,0813317 ! rRNA transcription GO:0009303 25 14 0,000 0,05481329 0,08242548 ! lactation GO:0007595 26 14 0,000 0,05481329 0,08237399 ! reproductive cellular process GO:0048610 20 14 0,000 0,05481329 0,08232257 ! tRNA modification GO:0006400 20 14 0,000 0,05481329 0,08227122 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05481329 0,08221993 ! regulation of S phase GO:0033261 23 14 0,000 0,05481329 0,0821687 ! water transport GO:0006833 21 14 0,000 0,05481329 0,08211754 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05481329 0,08206644 ! non-recombinational repair GO:0000726 25 14 0,000 0,05481329 0,0820154 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05481329 0,08196443 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05481329 0,08191352 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05481329 0,08186267 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05481329 0,08181189 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05481329 0,08176117 ! palate development GO:0060021 31 14 0,000 0,05481329 0,08171051 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05481329 0,08165992 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05481329 0,08160938 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05481329 0,08155891 ! arginine metabolic process GO:0006525 17 14 0,000 0,05481329 0,08150851 ! regulation of heart rate GO:0002027 24 14 0,000 0,05481329 0,08145816 ! organic alcohol transport GO:0015850 29 14 0,000 0,05481329 0,08140788 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05481329 0,08135766 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,05481329 0,0813075 ! embryo implantation GO:0007566 30 14 0,000 0,05481329 0,0812574 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05481329 0,08120737 ! L-amino acid transport GO:0015807 30 14 0,000 0,05481329 0,08115739 ! bone mineralization GO:0030282 17 14 0,000 0,05481329 0,08110748 ! stem cell development GO:0048864 43 14 0,000 0,05481329 0,08105763 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05481329 0,08100784 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05481329 0,08095811 ! cerebellum development GO:0021549 21 14 0,000 0,05481329 0,08090844 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05481329 0,08085884 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05481329 0,08080929 ! cofactor transport GO:0051181 26 14 0,000 0,05481329 0,08075981 ! NADP metabolic process GO:0006739 24 14 0,000 0,05481329 0,08071038 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,05481329 0,08066102 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05481329 0,08061171 ! intestinal absorption GO:0050892 25 14 0,000 0,05481329 0,08056247 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05481329 0,08051329 ! oxygen transport GO:0015671 21 14 0,000 0,05481329 0,08046416 ! male genitalia development GO:0030539 24 14 0,000 0,05481329 0,0804151 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05481329 0,0803661 ! regulation of axon extension GO:0030516 37 14 0,000 0,05481329 0,08031715 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05481329 0,08026827 ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,05508584 0,08061832 ! female pregnancy GO:0007565 164 94 1,000 0,05508584 0,08056931 ! transcription initiation GO:0006352 153 94 1,000 0,05508584 0,08052036 ! protein ubiquitination GO:0016567 217 97 1,000 0,05822856 0,08506249 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05861249 0,0855714 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,05861249 0,0855195 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,05861249 0,08546767 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,05861249 0,08541591 ! copper ion transport GO:0006825 20 15 0,000 0,05861249 0,0853642 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,05861249 0,08531256 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,05861249 0,08526098 ! sulfate transport GO:0008272 23 15 0,000 0,05861249 0,08520946 ! response to cAMP GO:0051591 22 15 0,000 0,05861249 0,08515801 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,05861249 0,08510662 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,05861249 0,08505528 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,05861249 0,08500402 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,05861249 0,08495281 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,05861249 0,08490166 ! response to hexose stimulus GO:0009746 22 15 0,000 0,05861249 0,08485058 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,05861249 0,08479956 ! pituitary gland development GO:0021983 29 15 0,000 0,05861249 0,08474859 ! vesicle coating GO:0006901 33 15 0,000 0,05861249 0,08469769 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,05861249 0,08464686 ! regulation of exocytosis GO:0017157 22 15 0,000 0,05861249 0,08459608 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,05861249 0,08454536 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,05861249 0,0844947 ! regulation of vasodilation GO:0042312 26 15 0,000 0,05861249 0,08444411 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,05861249 0,08439357 ! histone deacetylation GO:0016575 20 15 0,000 0,05861249 0,0843431 ! mRNA splice site selection GO:0006376 38 15 0,000 0,05861249 0,08429268 ! tissue regeneration GO:0042246 26 15 0,000 0,05861249 0,08424233 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05861249 0,08419204 ! water homeostasis GO:0030104 27 15 0,000 0,05861249 0,0841418 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05861249 0,08409163 ! muscle maintenance GO:0046716 26 15 0,000 0,05861249 0,08404151 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,05861249 0,08399146 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,05861249 0,08394147 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,05861249 0,08389153 ! heme biosynthetic process GO:0006783 29 15 0,000 0,05861249 0,08384165 ! cell killing GO:0001906 29 15 0,000 0,05861249 0,08379184 ! detection of bacterium GO:0016045 18 15 0,000 0,05861249 0,08374208 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,05861249 0,08369238 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,05861249 0,08364274 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,05861249 0,08359316 ! peptide hormone processing GO:0016486 23 15 0,000 0,05861249 0,08354364 ! response to virus GO:0009615 160 98 1,000 0,05928976 0,08445894 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06239656 0,08883202 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06239656 0,08877949 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06239656 0,08872702 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06239656 0,08867461 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06239656 0,08862227 ! bone remodeling GO:0046849 27 16 0,000 0,06239656 0,08856998 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06239656 0,08851776 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06239656 0,0884656 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06239656 0,0884135 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06239656 0,08836146 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06239656 0,08830948 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06239656 0,08825757 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06239656 0,08820571 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06239656 0,08815392 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06239656 0,08810218 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06239656 0,08805051 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06239656 0,0879989 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06239656 0,08794735 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06239656 0,08789585 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06239656 0,08784442 ! response to osmotic stress GO:0006970 25 16 0,000 0,06239656 0,08779305 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06239656 0,08774174 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06239656 0,08769049 ! fructose metabolic process GO:0006000 25 16 0,000 0,06239656 0,0876393 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06239656 0,08758817 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 32 16 0,000 0,06239656 0,0875371 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06239656 0,08748608 ! axon cargo transport GO:0008088 43 16 0,000 0,06239656 0,08743513 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06239656 0,08738424 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06239656 0,0873334 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06239656 0,08728263 ! neuron recognition GO:0008038 35 16 0,000 0,06239656 0,08723191 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06239656 0,08718125 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06239656 0,08713066 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06239656 0,08708012 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06239656 0,08702963 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06239656 0,08697921 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06239656 0,08692885 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06239656 0,08687854 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06239656 0,08682829 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06239656 0,0867781 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06239656 0,08672797 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06239656 0,0866779 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06616554 0,09186052 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06616554 0,09180754 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,06616554 0,09175463 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06616554 0,09170177 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06616554 0,09164898 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06616554 0,09159625 ! signal complex assembly GO:0007172 41 17 0,000 0,06616554 0,09154358 ! endothelial cell migration GO:0043542 28 17 0,000 0,06616554 0,09149097 ! inositol metabolic process GO:0006020 28 17 0,000 0,06616554 0,09143842 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06616554 0,09138592 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06616554 0,09133349 ! glial cell development GO:0021782 27 17 0,000 0,06616554 0,09128112 ! limbic system development GO:0021761 36 17 0,000 0,06616554 0,09122881 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06616554 0,09117656 ! adult walking behavior GO:0007628 33 17 0,000 0,06616554 0,09112437 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,06616554 0,09107224 ! heart looping GO:0001947 30 17 0,000 0,06616554 0,09102017 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06616554 0,09096816 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06616554 0,09091621 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06616554 0,09086432 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,06616554 0,09081248 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06616554 0,09076071 ! glycine metabolic process GO:0006544 28 17 0,000 0,06616554 0,09070899 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06616554 0,09065734 ! NAD metabolic process GO:0019674 29 17 0,000 0,06616554 0,09060574 ! membrane budding GO:0006900 37 17 0,000 0,06616554 0,0905542 ! DNA integration GO:0015074 29 17 0,000 0,06616554 0,09050272 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06616554 0,0904513 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06616554 0,09039993 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06616554 0,09034863 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06616554 0,09029738 ! genitalia development GO:0048806 30 17 0,000 0,06616554 0,09024619 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06616554 0,09019506 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06616554 0,09014399 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06616554 0,09009297 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06616554 0,09004201 ! steroid catabolic process GO:0006706 31 17 0,000 0,06616554 0,08999111 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06616554 0,08994027 ! gas transport GO:0015669 25 17 0,000 0,06616554 0,08988949 ! organic cation transport GO:0015695 31 17 0,000 0,06616554 0,08983876 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06616554 0,08978809 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06616554 0,08973748 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06616554 0,08968692 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06616554 0,08963642 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,06991949 0,09466871 ! neuron maturation GO:0042551 42 18 0,000 0,06991949 0,09461546 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,06991949 0,09456228 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,06991949 0,09450915 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,06991949 0,09445609 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,06991949 0,09440308 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,06991949 0,09435013 ! memory GO:0007613 31 18 0,000 0,06991949 0,09429725 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06991949 0,09424442 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,06991949 0,09419165 ! patterning of blood vessels GO:0001569 39 18 0,000 0,06991949 0,09413894 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,06991949 0,09408629 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,06991949 0,0940337 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,06991949 0,09398117 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06991949 0,09392869 ! response to retinoic acid GO:0032526 26 18 0,000 0,06991949 0,09387628 ! response to fungus GO:0009620 21 18 0,000 0,06991949 0,09382392 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,06991949 0,09377162 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,06991949 0,09371938 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,06991949 0,0936672 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,06991949 0,09361508 ! vitamin transport GO:0051180 27 18 0,000 0,06991949 0,09356301 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,06991949 0,093511 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,06991949 0,09345905 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,06991949 0,09340716 ! nerve development GO:0021675 28 18 0,000 0,06991949 0,09335532 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,06991949 0,09330354 ! protein secretion GO:0009306 39 19 0,000 0,07365848 0,09823852 ! positive regulation of translation GO:0045727 30 19 0,000 0,07365848 0,09818409 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07365848 0,09812973 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07365848 0,09807542 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07365848 0,09802118 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07365848 0,09796699 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07365848 0,09791287 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07365848 0,0978588 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07365848 0,0978048 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07365848 0,09775085 ! cerebral cortex development GO:0021987 36 19 0,000 0,07365848 0,09769696 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,07365848 0,09764314 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,07365848 0,09758937 ! heme metabolic process GO:0042168 36 19 0,000 0,07365848 0,09753566 ! actin filament bundle formation GO:0051017 42 19 0,000 0,07365848 0,09748201 ! neuromuscular junction development GO:0007528 34 19 0,000 0,07365848 0,09742842 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07365848 0,09737489 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07365848 0,09732141 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,07365848 0,097268 ! peptide cross-linking GO:0018149 37 19 0,000 0,07365848 0,09721464 ! protein export from nucleus GO:0006611 36 19 0,000 0,07365848 0,09716134 ! heart process GO:0003015 30 19 0,000 0,07365848 0,0971081 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07365848 0,09705492 GO:0006692|prostanoid metabolic process, ! visual learning GO:0008542 36 19 0,000 0,07365848 0,0970018 ! G1 phase GO:0051318 40 19 0,000 0,07365848 0,09694874 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07365848 0,09689573 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07365848 0,09684278 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,07365848 0,09678989 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07365848 0,09673706 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07365848 0,09668428 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07365848 0,09663157 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07365848 0,09657891 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07365848 0,0965263 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07365848 0,09647376 ! cilium assembly GO:0042384 37 19 0,000 0,07365848 0,09642127 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07365848 0,09636884 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,07738255 0,1011861 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,07738255 0,10113114 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,07738255 0,10107623 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,07738255 0,10102139 ! cAMP metabolic process GO:0046058 36 20 0,000 0,07738255 0,10096661 ! response to vitamin GO:0033273 31 20 0,000 0,07738255 0,10091188 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,07738255 0,10085722 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,07738255 0,10080261 ! retinoid metabolic process GO:0001523 32 20 0,000 0,07738255 0,10074807 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,07738255 0,10069358 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,07738255 0,10063915 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,07738255 0,10058478 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,07738255 0,10053047 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,07738255 0,10047621 ! body fluid secretion GO:0007589 31 20 0,000 0,07738255 0,10042202 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,07738255 0,10036788 ! peptide secretion GO:0002790 35 20 0,000 0,07738255 0,10031381 ! stem cell differentiation GO:0048863 53 20 0,000 0,07738255 0,10025979 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,07738255 0,10020583 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,07738255 0,10015192 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,07738255 0,10009808 ! sensory perception of pain GO:0019233 30 20 0,000 0,07738255 0,10004429 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,07738255 0,09999056 ! diencephalon development GO:0021536 34 20 0,000 0,07738255 0,09993689 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,07738255 0,09988328 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,07738255 0,09982972 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,07738255 0,09977622 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,07738255 0,09972278 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,07738255 0,09966939 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,07738255 0,09961606 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,07738255 0,09956279 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,07738255 0,09950958 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,07738255 0,09945642 ! actin filament-based movement GO:0030048 43 20 0,000 0,07738255 0,09940332 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,07738255 0,09935028 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,07738255 0,09929729 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,07738255 0,09924436 ! negative regulation of translation GO:0017148 29 20 0,000 0,07738255 0,09919149 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,07738255 0,09913867 ! regulation of cell killing GO:0031341 42 21 0,000 0,08109178 0,10383546 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08109178 0,10378023 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08109178 0,10372506 ! hormone secretion GO:0046879 38 21 0,000 0,08109178 0,10366994 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08109178 0,10361489 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08109178 0,10355989 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08109178 0,10350495 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08109178 0,10345007 ! axis specification GO:0009798 38 21 0,000 0,08109178 0,10339525 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08109178 0,10334048 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08109178 0,10328578 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08109178 0,10323113 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08109178 0,10317654 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08109178 0,103122 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08109178 0,10306753 ! cytolysis GO:0019835 24 21 0,000 0,08109178 0,10301311 ! vasodilation GO:0042311 39 21 0,000 0,08109178 0,10295875 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08109178 0,10290445 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08109178 0,1028502 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08109178 0,10279601 ! DNA modification GO:0006304 34 21 0,000 0,08109178 0,10274188 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08109178 0,10268781 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08109178 0,10263379 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08109178 0,10257983 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08109178 0,10252592 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08109178 0,10247208 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08109178 0,10241829 ! collagen catabolic process GO:0030574 28 21 0,000 0,08109178 0,10236455 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08109178 0,10231087 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08478623 0,10691596 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08478623 0,10685996 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08478623 0,10680401 ! microtubule-based transport GO:0010970 54 22 0,000 0,08478623 0,10674812 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08478623 0,10669229 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08478623 0,10663652 ! keratinization GO:0031424 28 22 0,000 0,08478623 0,1065808 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08478623 0,10652515 ! sensory perception of taste GO:0050909 28 22 0,000 0,08478623 0,10646955 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 0,000 0,08478623 0,10641401 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08478623 0,10635853 ! vacuolar transport GO:0007034 36 22 0,000 0,08478623 0,1063031 ! lysosome organization GO:0007040 41 22 0,000 0,08478623 0,10624774 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08478623 0,10619243 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,08478623 0,10613718 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08478623 0,10608199 ! fucose metabolic process GO:0006004 39 22 0,000 0,08478623 0,10602685 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08478623 0,10597177 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08478623 0,10591675 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08478623 0,10586178 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08478623 0,10580688 ! sarcomere organization GO:0045214 30 22 0,000 0,08478623 0,10575203 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08478623 0,10569723 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08478623 0,1056425 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08478623 0,10558781 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08478623 0,10553319 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08478623 0,10547862 ! protein stabilization GO:0050821 39 22 0,000 0,08478623 0,10542411 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,08846594 0,10994269 ! gluconeogenesis GO:0006094 33 23 0,000 0,08846594 0,10988593 ! viral genome replication GO:0019079 41 23 0,000 0,08846594 0,10982923 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,08846594 0,10977258 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,08846594 0,109716 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,08846594 0,10965947 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,08846594 0,10960301 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,08846594 0,1095466 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,08846594 0,10949025 ! visual behavior GO:0007632 42 23 0,000 0,08846594 0,10943395 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,08846594 0,10937772 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,08846594 0,10932154 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,08846594 0,10926542 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,08846594 0,10920936 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,08846594 0,10915335 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,08846594 0,10909741 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,08846594 0,10904152 GO:0051693|actin filament capping, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,08846594 0,10898568 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,08846594 0,10892991 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,08846594 0,10887419 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,08846594 0,10881853 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,08846594 0,10876292 ! fatty acid transport GO:0015908 44 23 0,000 0,08846594 0,10870737 ! platelet activation GO:0030168 37 23 0,000 0,08846594 0,10865188 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,08846594 0,10859645 ! hormone transport GO:0009914 40 23 0,000 0,08846594 0,10854107 ! cell-cell recognition GO:0009988 25 23 0,000 0,08846594 0,10848575 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,08846594 0,10843048 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,08846594 0,10837528 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,08846594 0,10832012 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,08846594 0,10826503 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,08846594 0,10820998 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09213097 0,11263573 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09213097 0,11257853 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09213097 0,11252138 ! vesicle docking GO:0048278 47 24 0,000 0,09213097 0,11246429 ! spinal cord development GO:0021510 47 24 0,000 0,09213097 0,11240726 ! vacuole organization GO:0007033 43 24 0,000 0,09213097 0,11235029 ! digestive system process GO:0022600 39 24 0,000 0,09213097 0,11229337 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09213097 0,11223652 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09213097 0,11217972 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09213097 0,11212297 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09213097 0,11206629 ! membrane depolarization GO:0051899 39 24 0,000 0,09213097 0,11200966 ! pallium development GO:0021543 49 24 0,000 0,09213097 0,11195309 ! pentose metabolic process GO:0019321 35 24 0,000 0,09213097 0,11189658 ! regulation of oxidoreductase activity GO:0051341 46 24 0,000 0,09213097 0,11184012 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09213097 0,11178372 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09213097 0,11172738 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09213097 0,11167109 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09213097 0,11161486 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09213097 0,11155869 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09213097 0,11150257 ! regulation of amine transport GO:0051952 40 24 0,000 0,09213097 0,11144652 ! myelination GO:0042552 45 25 0,000 0,09578139 0,11580404 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,09578139 0,11574587 ! phototransduction GO:0007602 33 25 0,000 0,09578139 0,11568777 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,09578139 0,11562972 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,09578139 0,11557173 ! sperm motility GO:0030317 31 25 0,000 0,09578139 0,1155138 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,09578139 0,11545593 ! receptor metabolic process GO:0043112 46 25 0,000 0,09578139 0,11539811 ! chromosome condensation GO:0030261 45 25 0,000 0,09578139 0,11534036 ! neural crest cell development GO:0014032 54 25 0,000 0,09578139 0,11528266 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,09578139 0,11522502 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,09578139 0,11516743 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,09578139 0,11510991 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,09578139 0,11505244 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,09578139 0,11499503 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,09578139 0,11493767 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,09578139 0,11488038 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,09578139 0,11482314 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,09578139 0,11476595 ! telomere organization GO:0032200 43 25 0,000 0,09578139 0,11470883 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,09578139 0,11465176 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,09578139 0,11459475 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,09941726 0,11888565 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,09941726 0,11882659 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,09941726 0,11876759 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,09941726 0,11870865 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,09941726 0,11864976 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,09941726 0,11859094 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,09941726 0,11853217 ! tube lumen formation GO:0035148 50 26 0,000 0,09941726 0,11847347 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,09941726 0,11841481 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,09941726 0,11835622 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,09941726 0,11829769 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,09941726 0,11823921 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,09941726 0,11818079 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,09941726 0,11812243 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,09941726 0,11806413 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,09941726 0,11800588 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,09941726 0,1179477 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,09941726 0,11788956 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,09941726 0,11783149 ! blastocyst development GO:0001824 49 26 0,000 0,09941726 0,11777347 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,09941726 0,11771551 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,09941726 0,11765761 ! neuron fate commitment GO:0048663 48 27 0,000 0,10303862 0,12188345 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,10303862 0,12182355 ! iron ion transport GO:0006826 59 27 0,000 0,10303862 0,12176372 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10303862 0,12170394 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10303862 0,12164423 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10303862 0,12158457 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10303862 0,12152497 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10303862 0,12146542 ! autophagy GO:0006914 41 27 0,000 0,10303862 0,12140594 ! primary neural tube formation GO:0014020 51 27 0,000 0,10303862 0,12134652 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10303862 0,12128715 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10303862 0,12122784 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10303862 0,12116859 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,10303862 0,12110939 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10303862 0,12105026 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,10303862 0,12099118 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,10664555 0,12516546 ! circadian rhythm GO:0007623 50 28 0,000 0,10664555 0,12510443 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,10664555 0,12504346 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,10664555 0,12498256 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,10664555 0,12492171 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,10664555 0,12486092 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,10664555 0,12480019 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,10664555 0,12473952 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,10664555 0,12467891 ! synaptogenesis GO:0007416 42 28 0,000 0,10664555 0,12461835 ! lipid oxidation GO:0034440 43 28 0,000 0,10664555 0,12455786 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,10664555 0,12449742 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,10664555 0,12443705 ! translational initiation GO:0006413 65 29 0,000 0,11023809 0,12856657 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11023809 0,12850428 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11023809 0,12844205 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11023809 0,12837988 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,11023809 0,12831777 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,11023809 0,12825572 ! cell fate determination GO:0001709 60 29 0,000 0,11023809 0,12819373 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11023809 0,12813181 ! detection of light stimulus GO:0009583 38 29 0,000 0,11023809 0,12806994 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,11023809 0,12800813 ! regulation of coagulation GO:0050818 46 29 0,000 0,11023809 0,12794638 ! zinc ion transport GO:0006829 45 30 0,000 0,1138163 0,13203569 ! membrane docking GO:0022406 61 30 0,000 0,1138163 0,13197205 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,1138163 0,13190848 ! regulation of innate immune response GO:0045088 51 30 0,000 0,1138163 0,13184497 ! acute-phase response GO:0006953 49 30 0,000 0,1138163 0,13178153 ! myofibril assembly GO:0030239 47 30 0,000 0,1138163 0,13171814 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,1138163 0,13165481 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1138163 0,13159155 ! phospholipid transport GO:0015914 51 30 0,000 0,1138163 0,13152834 ! ensheathment of neurons GO:0007272 57 30 0,000 0,1138163 0,1314652 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1138163 0,13140212 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1138163 0,13133909 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,1138163 0,13127613 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,1138163 0,13121323 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,11738024 0,13525711 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,11738024 0,13519236 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,11738024 0,13512768 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,11738024 0,13506305 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,11738024 0,13499849 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,11738024 0,13493399 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,11738024 0,13486955 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,11738024 0,13480518 ! peptide transport GO:0015833 55 31 0,000 0,11738024 0,13474086 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,11738024 0,13467661 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,11738024 0,13461242 ! natural killer cell activation GO:0030101 45 31 0,000 0,11738024 0,13454828 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,11738024 0,13448421 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,11738024 0,1344202 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,11738024 0,13435625 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,11738024 0,13429237 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,11738024 0,13422854 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,12092996 0,13822208 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12092996 0,13815645 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12092996 0,13809088 ! cholesterol transport GO:0030301 56 32 0,000 0,12092996 0,13802537 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,12092996 0,13795993 ! spliceosome assembly GO:0000245 67 32 0,000 0,12092996 0,13789454 ! spindle organization GO:0007051 46 32 0,000 0,12092996 0,13782922 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12092996 0,13776396 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12092996 0,13769876 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,12092996 0,13763362 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,12092996 0,13756855 ! muscle cell development GO:0055001 49 32 0,000 0,12092996 0,13750354 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,12092996 0,13743858 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12092996 0,13737369 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,12092996 0,13730886 ! peripheral nervous system development GO:0007422 64 32 0,000 0,12092996 0,1372441 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,12092996 0,13717939 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12092996 0,13711474 ! gene silencing GO:0016458 65 32 0,000 0,12092996 0,13705016 ! protein targeting to membrane GO:0006612 68 33 0,000 0,12446552 0,14099061 ! ceramide metabolic process GO:0006672 64 33 0,000 0,12446552 0,14092426 ! cell fate specification GO:0001708 52 33 0,000 0,12446552 0,14085797 ! sterol transport GO:0015918 57 33 0,000 0,12446552 0,14079175 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,12446552 0,14072559 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,12446552 0,14065949 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,12446552 0,14059345 ! glial cell differentiation GO:0010001 63 34 0,000 0,12798699 0,14450337 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,12798699 0,1444356 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,12798699 0,14436788 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,12798699 0,14430023 ! mismatch repair GO:0006298 46 34 0,000 0,12798699 0,14423264 ! spermatid development GO:0007286 63 34 0,000 0,12798699 0,14416512 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,12798699 0,14409766 ! placenta development GO:0001890 53 34 0,000 0,12798699 0,14403026 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,1314944 0,14790815 ! negative regulation of secretion GO:0051048 63 35 0,000 0,1314944 0,14783903 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,1314944 0,14776998 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,1314944 0,147701 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,1314944 0,14763207 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,1314944 0,14756321 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,1314944 0,14749442 ! cytokine production GO:0001816 59 35 0,000 0,1314944 0,14742569 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,1314944 0,14735702 ! neural tube formation GO:0001841 67 35 0,000 0,1314944 0,14728842 ! vesicle localization GO:0051648 64 35 0,000 0,1314944 0,14721988 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,13498783 0,1510608 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,13498783 0,15099057 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,13498783 0,1509204 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,13498783 0,15085031 ! regulation of proteolysis GO:0030162 72 36 0,000 0,13498783 0,15078027 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,13498783 0,15071031 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,13498783 0,1506404 ! aerobic respiration GO:0009060 55 36 0,000 0,13498783 0,15057057 ! embryonic organ development GO:0048568 57 36 0,000 0,13498783 0,15050079 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,13498783 0,15043108 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,13498783 0,15036144 ! RNA export from nucleus GO:0006405 56 37 0,000 0,13846731 0,15416583 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,13846731 0,15409452 ! meiosis I GO:0007127 65 37 0,000 0,13846731 0,15402328 ! sister chromatid segregation GO:0000819 58 37 0,000 0,13846731 0,15395211 ! actomyosin structure organization GO:0031032 62 37 0,000 0,13846731 0,153881 ! organic anion transport GO:0015711 68 37 0,000 0,13846731 0,15380995 ! tissue remodeling GO:0048771 76 37 0,000 0,13846731 0,15373897 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,13846731 0,15366806 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,13846731 0,15359721 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,13846731 0,15352643 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,13846731 0,15345572 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 66 37 0,000 0,13846731 0,15338506 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,14193292 0,15715168 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,14193292 0,1570794 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,14193292 0,15700718 ! lipid homeostasis GO:0055088 67 38 0,000 0,14193292 0,15693502 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,14193292 0,15686293 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,14193292 0,15679091 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,14193292 0,15671896 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,14193292 0,15664707 ! mRNA catabolic process GO:0006402 71 39 0,000 0,1453847 0,16038312 ! mammary gland development GO:0030879 86 39 0,000 0,1453847 0,16030962 ! learning GO:0007612 77 39 0,000 0,1453847 0,16023619 ! organic ether metabolic process GO:0018904 55 39 0,000 0,1453847 0,16016282 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1453847 0,16008952 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1453847 0,16001628 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,1453847 0,15994312 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1453847 0,15987001 ! RNA modification GO:0009451 57 39 0,000 0,1453847 0,15979698 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1453847 0,15972401 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,14882271 0,16342649 ! feeding behavior GO:0007631 59 40 0,000 0,14882271 0,16335194 ! negative regulation of binding GO:0051100 72 40 0,000 0,14882271 0,16327745 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,14882271 0,16320303 ! maintenance of protein location GO:0045185 91 40 0,000 0,14882271 0,16312868 ! cytokinesis GO:0000910 72 40 0,000 0,14882271 0,16305439 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,152247 0,16673022 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,152247 0,16665436 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,152247 0,16657858 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,152247 0,16650286 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,152247 0,16642721 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,152247 0,16635163 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,152247 0,16627612 ! polyol metabolic process GO:0019751 66 41 0,000 0,152247 0,16620068 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,152247 0,1661253 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,15565763 0,16976984 ! regulation of tube size GO:0035150 71 42 0,000 0,15565763 0,16969292 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,15565763 0,16961606 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,15565763 0,16953928 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,15565763 0,16946256 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,15565763 0,16938592 ! neuron migration GO:0001764 79 42 0,000 0,15565763 0,16930934 ! regulation of protein secretion GO:0050708 71 42 0,000 0,15565763 0,16923284 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,15565763 0,1691564 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,15905466 0,17276998 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,15905466 0,17269201 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,15905466 0,17261412 ! glucose transport GO:0015758 65 43 0,000 0,15905466 0,17253629 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,15905466 0,17245854 ! neural tube development GO:0021915 77 43 0,000 0,15905466 0,17238086 ! striated muscle contraction GO:0006941 77 43 0,000 0,15905466 0,17230324 ! phagocytosis GO:0006909 90 43 0,000 0,15905466 0,1722257 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,15905466 0,17214822 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,16243812 0,17573117 ! hexose transport GO:0008645 67 44 0,000 0,16243812 0,17565219 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 0,000 0,16243812 0,17557328 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,16243812 0,17549444 ! maintenance of location in cell GO:0051651 97 44 0,000 0,16243812 0,17541567 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,16580809 0,17897455 ! glycolysis GO:0006096 65 45 0,000 0,16580809 0,17889429 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,16580809 0,1788141 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,16580809 0,17873399 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,16580809 0,17865395 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,16580809 0,17857398 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,16580809 0,17849408 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,16916461 0,18202596 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,16916461 0,18194459 ! endosome transport GO:0016197 108 47 0,000 0,17250773 0,18545737 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,17250773 0,18537454 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,17250773 0,18529179 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,17250773 0,1852091 ! JNK cascade GO:0007254 91 47 0,000 0,17250773 0,18512649 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,17250773 0,18504396 ! methylation GO:0032259 90 47 0,000 0,17250773 0,1849615 ! protein homooligomerization GO:0051260 76 47 0,000 0,17250773 0,18487911 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,17583751 0,18836378 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,17583751 0,18827995 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,17583751 0,1881962 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,17583751 0,18811252 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,17915401 0,19157535 ! regulation of action potential GO:0001508 95 49 0,000 0,17915401 0,19149025 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,17915401 0,19140521 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,17915401 0,19132026 ! regulation of ion transport GO:0043269 77 49 0,000 0,17915401 0,19123538 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,17915401 0,19115057 ! endocrine system development GO:0035270 104 49 0,000 0,17915401 0,19106584 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,17915401 0,19098119 ! inner ear development GO:0048839 79 50 0,000 0,18245727 0,19441638 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,18245727 0,19433032 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,18574734 0,19774695 ! excretion GO:0007588 83 51 0,000 0,18574734 0,19765949 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,18574734 0,19757211 ! chromatin remodeling GO:0006338 109 51 0,000 0,18574734 0,1974848 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,18574734 0,19739757 ! regulation of cell shape GO:0008360 125 51 0,000 0,18574734 0,19731042 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,18902428 0,20070275 ! membrane fusion GO:0006944 110 52 0,000 0,18902428 0,20061422 ! amino acid activation GO:0043038 92 52 0,000 0,18902428 0,20052576 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 0,000 0,18902428 0,20043739 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,19228815 0,20380849 ! RNA catabolic process GO:0006401 93 53 0,000 0,19228815 0,20371875 ! regulation of translational initiation GO:0006446 82 53 0,000 0,19228815 0,20362909 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,19228815 0,2035395 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,19228815 0,20344999 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,19228815 0,20336056 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,19228815 0,20327121 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,19553898 0,20661695 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,19553898 0,20652625 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,19553898 0,20643563 ! cell recognition GO:0008037 85 54 0,000 0,19553898 0,20634509 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,19553898 0,20625462 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,19553898 0,20616424 ! chloride transport GO:0006821 90 55 0,000 0,19877684 0,20948624 ! glucose catabolic process GO:0006007 82 55 0,000 0,19877684 0,20939452 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,19877684 0,20930288 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,19877684 0,20921132 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,19877684 0,20911984 ! RNA elongation GO:0006354 79 55 0,000 0,19877684 0,20902845 ! nuclear export GO:0051168 97 55 0,000 0,19877684 0,20893713 ! regulation of actin filament length GO:0030832 105 56 0,000 0,20200178 0,21223418 ! sensory perception of smell GO:0007608 80 56 0,000 0,20200178 0,21214154 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,20200178 0,21204899 ! proton transport GO:0015992 94 56 0,000 0,20200178 0,21195651 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,20200178 0,21186411 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,20521384 0,21513922 ! maintenance of location GO:0051235 118 57 0,000 0,20521384 0,21504551 ! hydrogen transport GO:0006818 97 58 0,000 0,20841308 0,21830295 ! regulation of endocytosis GO:0030100 91 58 0,000 0,20841308 0,21820795 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,20841308 0,21811304 ! regulation of cellular component size GO:0032535 109 59 0,000 0,21159955 0,22135153 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,21159955 0,22125533 GO:0032313|regulation of Rab GTPase activity, ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,21159955 0,22115921 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,21477329 0,22437887 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,21477329 0,22428149 ! camera-type eye development GO:0043010 116 60 0,000 0,21477329 0,22418418 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,21793437 0,22738512 ! tRNA processing GO:0008033 89 61 0,000 0,21793437 0,22728656 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,21793437 0,22718808 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,22108282 0,23037041 ! regulation of mitosis GO:0007088 105 63 0,000 0,22421871 0,23353689 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,22421871 0,23343583 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,22421871 0,23333486 ! cell redox homeostasis GO:0045454 102 64 0,000 0,22734207 0,23648293 ! single fertilization GO:0007338 75 64 0,000 0,22734207 0,23638073 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,23045296 0,2395118 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,23045296 0,23940838 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,23045296 0,23930506 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,23355143 0,24241792 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,23355143 0,24231338 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,23663752 0,24540943 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,23663752 0,2453037 ! hexose catabolic process GO:0019320 104 67 0,000 0,23663752 0,24519805 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,23663752 0,2450925 ! amino acid transport GO:0006865 125 68 0,000 0,2397113 0,24816927 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,2397113 0,24806253 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,2397113 0,24795588 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 0,000 0,2397113 0,24784932 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,2397113 0,24774286 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,24277279 0,2507992 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,24277279 0,25069156 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,24277279 0,25058402 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,24277279 0,25047656 ! antigen processing and presentation GO:0019882 104 69 0,000 0,24277279 0,2503692 ! appendage morphogenesis GO:0035107 135 70 0,000 0,24582206 0,25340526 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,24885916 0,25642618 ! appendage development GO:0048736 136 71 0,000 0,24885916 0,25631641 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,24885916 0,25620673 ! carbohydrate transport GO:0008643 110 72 0,000 0,25188412 0,25921009 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,25188412 0,25909927 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,25188412 0,25898854 ! learning or memory GO:0007611 147 73 0,000 0,254897 0,26197445 ! regulation of blood pressure GO:0008217 125 73 0,000 0,254897 0,26186259 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,254897 0,26175083 ! axon guidance GO:0007411 139 73 0,000 0,254897 0,26163916 ! fertilization GO:0009566 90 73 0,000 0,254897 0,26152759 ! transition metal ion transport GO:0000041 126 74 0,000 0,25789785 0,2644937 ! neurotransmitter transport GO:0006836 123 74 0,000 0,25789785 0,26438101 ! meiosis GO:0007126 121 74 0,000 0,25789785 0,26426841 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,25789785 0,26415591 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,25789785 0,2640435 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,26088671 0,26698997 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,26088671 0,26687646 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,26088671 0,26676304 ! meiotic cell cycle GO:0051321 122 75 0,000 0,26088671 0,26664971 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,26386363 0,26957788 ! defense response to bacterium GO:0042742 89 76 0,000 0,26386363 0,26946346 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,26386363 0,26934913 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,26386363 0,2692349 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,26682866 0,27214488 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,26682866 0,27202956 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,26682866 0,27191434 ! blood coagulation GO:0007596 146 78 0,000 0,26978185 0,27480742 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,26978185 0,27469113 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,26978185 0,27457493 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,27272324 0,27745121 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,27272324 0,27733395 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,27272324 0,27721678 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,27565288 0,28007636 ! inorganic anion transport GO:0015698 138 80 0,000 0,27565288 0,27995814 ! digestion GO:0007586 112 81 0,000 0,27857081 0,28280227 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,27857081 0,28268299 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,28147709 0,28551175 ! hemostasis GO:0007599 158 84 0,000 0,28725486 0,29124955 ! regulation of ligase activity GO:0051340 142 84 0,000 0,28725486 0,29112687 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,28725486 0,29100429 ! response to unfolded protein GO:0006986 131 85 0,000 0,29012644 0,29378965 ! nucleosome assembly GO:0006334 122 85 0,000 0,29012644 0,29366605 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,29012644 0,29354256 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,29298654 0,29631174 ! chromatin assembly GO:0031497 124 86 0,000 0,29298654 0,29618724 ! alcohol catabolic process GO:0046164 130 86 0,000 0,29298654 0,29606284 ! amine transport GO:0015837 155 86 0,000 0,29298654 0,29593855 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,29583522 0,29869053 ! cellular respiration GO:0045333 135 88 0,000 0,29867251 0,30142872 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,29867251 0,30130233 ! cellular defense response GO:0006968 114 89 0,000 0,30149847 0,3040257 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,30431313 0,3067354 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,30431313 0,30660695 ! sterol metabolic process GO:0016125 152 91 0,000 0,30711655 0,30930197 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,30711655 0,30917256 ! nucleosome organization GO:0034728 138 92 0,000 0,30990876 0,31185298 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,30990876 0,3117226 ! vitamin metabolic process GO:0006766 139 92 0,000 0,30990876 0,31159234 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,31268981 0,31425717 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,31268981 0,31412596 ! regulation of T cell activation GO:0050863 158 94 0,000 0,31545974 0,31677635 ! forebrain development GO:0030900 188 95 0,000 0,31821861 0,31941342 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,31821861 0,31928022 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,32096644 0,32190298 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,32096644 0,32176886 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,32370329 0,3243774 ! hormone metabolic process GO:0042445 157 97 0,000 0,32370329 0,32424235 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,32642921 0,32683673 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,32642921 0,32670078 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,32914422 0,32928108 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,32914422 0,32914422