pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-VanDeVijver//out-0.3-01-0.03-300-VanDeVijver//go_data/528-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 1,166E-12 2,85E-09 ! regulation of ossification GO:0030278 123 50 6,000 8,063E-10 9,849E-07 ! cartilage development GO:0051216 99 53 6,000 1,233E-09 1,004E-06 ! epithelial to mesenchymal transition GO:0001837 30 15 4,000 2,058E-09 1,257E-06 ! regulation of bone remodeling GO:0046850 143 57 6,000 2,088E-09 1,02E-06 ! regulation of tissue remodeling GO:0034103 146 58 6,000 2,367E-09 9,638E-07 ! mesenchymal cell development GO:0014031 94 41 5,000 1,035E-08 3,611E-06 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! collagen fibril organization GO:0030199 62 21 4,000 1,369E-08 4,182E-06 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 1,851E-08 5,025E-06 ! osteoblast differentiation GO:0001649 63 26 4,000 4,36E-08 1,065E-05 ! ossification GO:0001503 205 91 6,000 5,747E-08 1,276E-05 ! bone development GO:0060348 206 92 6,000 6,201E-08 1,262E-05 ! chondrocyte differentiation GO:0002062 27 11 3,000 6,243E-08 1,173E-05 ! release of cytochrome c from mitochondria GO:0001836 31 14 3,000 1,877E-07 3,276E-05 ! neutrophil chemotaxis GO:0030593 29 17 3,000 4,424E-07 7,206E-05 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 2,000 5,21E-07 7,955E-05 ! regulation of gene-specific transcription GO:0032583 102 46 4,000 8,553E-07 1,229E-04 ! positive regulation of ossification GO:0045778 50 20 3,000 8,928E-07 1,212E-04 ! apoptotic mitochondrial changes GO:0008637 42 20 3,000 8,928E-07 1,148E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 1,039E-06 1,269E-04 ! nuclear migration GO:0007097 13 6 2,000 1,039E-06 1,209E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 1,039E-06 1,154E-04 GO:0031272|regulation of pseudopodium assembly, ! positive regulation of osteoblast differentiation GO:0045669 52 21 3,000 1,1E-06 1,168E-04 ! positive regulation of bone remodeling GO:0046852 54 22 3,000 1,34E-06 1,364E-04 GO:0034105|positive regulation of tissue remodeling, ! positive regulation of growth GO:0045927 96 53 4,000 1,753E-06 1,713E-04 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 2,000 1,814E-06 1,704E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 1,814E-06 1,641E-04 ! B cell lineage commitment GO:0002326 21 7 2,000 1,814E-06 1,582E-04 ! T cell lineage commitment GO:0002360 16 7 2,000 1,814E-06 1,528E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 1,935E-06 1,576E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 3,000 2,707E-06 2,133E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 2,707E-06 2,067E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 68 26 3,000 2,707E-06 2,004E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 2,894E-06 2,079E-04 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 2,000 2,894E-06 2,02E-04 ! ER overload response GO:0006983 13 8 2,000 2,894E-06 1,964E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 2,894E-06 1,911E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 2,894E-06 1,86E-04 ! insulin receptor signaling pathway GO:0008286 66 27 3,000 3,168E-06 1,985E-04 ! peptidyl-tyrosine modification GO:0018212 57 28 3,000 3,686E-06 2,251E-04 ! induction of positive chemotaxis GO:0050930 17 9 2,000 4,328E-06 2,579E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 4,328E-06 2,518E-04 ! macrophage differentiation GO:0030225 15 9 2,000 4,328E-06 2,459E-04 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 4,506E-06 2,502E-04 ! negative regulation of cell growth GO:0030308 142 67 4,000 5,656E-06 3,07E-04 ! extracellular matrix organization GO:0030198 146 68 4,000 6,086E-06 3,232E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 6,166E-06 3,205E-04 ! response to mechanical stimulus GO:0009612 60 32 3,000 6,398E-06 3,256E-04 ! negative regulation of cell size GO:0045792 144 69 4,000 6,542E-06 3,262E-04 ! leukocyte chemotaxis GO:0030595 55 33 3,000 7,259E-06 3,547E-04 GO:0060326|cell chemotaxis, ! detection of mechanical stimulus GO:0050982 22 11 2,000 8,456E-06 4,05E-04 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 8,456E-06 3,972E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 8,456E-06 3,898E-04 GO:0010829|negative regulation of glucose transport, ! nucleus localization GO:0051647 22 11 2,000 8,456E-06 3,825E-04 ! positive regulation of cell development GO:0010720 85 36 3,000 1,036E-05 4,601E-04 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 1,124E-05 4,905E-04 GO:0050927|positive regulation of positive chemotaxis, ! regulation of cell projection assembly GO:0060491 33 12 2,000 1,124E-05 4,819E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 1,124E-05 4,736E-04 ! cellular response to insulin stimulus GO:0032869 85 38 3,000 1,29E-05 5,343E-04 ! carbohydrate homeostasis GO:0033500 59 39 3,000 1,434E-05 5,838E-04 GO:0042593|glucose homeostasis, ! gland morphogenesis GO:0022612 31 13 2,000 1,458E-05 5,837E-04 ! negative regulation of growth GO:0045926 168 85 4,000 1,819E-05 7,169E-04 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 1,819E-05 7,055E-04 ! hair follicle morphogenesis GO:0031069 27 14 2,000 1,85E-05 7,062E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 1,85E-05 6,953E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 2,000 1,85E-05 6,848E-04 GO:0060675|ureteric bud morphogenesis, ! response to gamma radiation GO:0010332 30 14 2,000 1,85E-05 6,745E-04 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 2,306E-05 8,285E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 3,000 2,787E-05 9,868E-04 ! leukocyte migration GO:0050900 75 46 3,000 2,787E-05 9,727E-04 ! pigmentation GO:0043473 103 46 3,000 2,787E-05 9,59E-04 ! positive regulation of neuron apoptosis GO:0043525 32 16 2,000 2,83E-05 9,604E-04 ! response to insulin stimulus GO:0032868 98 47 3,000 3,037E-05 1,017E-03 ! filopodium assembly GO:0046847 42 17 2,000 3,427E-05 1,132E-03 ! myoblast differentiation GO:0045445 50 17 2,000 3,427E-05 1,116E-03 ! regulation of DNA metabolic process GO:0051052 188 97 4,000 3,448E-05 1,108E-03 ! leukocyte differentiation GO:0002521 232 98 4,000 3,622E-05 1,149E-03 ! epidermis morphogenesis GO:0048730 43 18 2,000 4,102E-05 1,285E-03 ! microspike assembly GO:0030035 46 18 2,000 4,102E-05 1,268E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 4,857E-05 1,483E-03 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 2,000 4,857E-05 1,465E-03 ! regulation of neuron apoptosis GO:0043523 117 53 3,000 4,9E-05 1,46E-03 ! response to UV GO:0009411 120 55 3,000 5,674E-05 1,67E-03 ! response to alkaloid GO:0043279 38 20 2,000 5,699E-05 1,657E-03 ! pancreas development GO:0031016 40 20 2,000 5,699E-05 1,638E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 5,699E-05 1,619E-03 ! regulation of glucose import GO:0046324 30 20 2,000 5,699E-05 1,6E-03 GO:0010827|regulation of glucose transport, ! regulation of DNA replication GO:0006275 105 56 3,000 6,093E-05 1,691E-03 ! heart morphogenesis GO:0003007 105 57 3,000 6,533E-05 1,793E-03 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 2,000 6,63E-05 1,8E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 6,63E-05 1,78E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 6,997E-05 1,858E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 7,656E-05 2,011E-03 ! ureteric bud development GO:0001657 50 22 2,000 7,656E-05 1,99E-03 ! cell aging GO:0007569 48 22 2,000 7,656E-05 1,969E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 7,656E-05 1,948E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! peptidyl-serine modification GO:0018209 50 22 2,000 7,656E-05 1,928E-03 ! regulation of heart contraction GO:0008016 123 61 3,000 8,531E-05 2,127E-03 ! negative regulation of response to stimulus GO:0048585 106 61 3,000 8,531E-05 2,105E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 8,78E-05 2,145E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 8,78E-05 2,124E-03 ! regulation of bone mineralization GO:0030500 54 23 2,000 8,78E-05 2,103E-03 ! skeletal system morphogenesis GO:0048705 118 63 3,000 9,681E-05 2,296E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 1,094E-04 2,57E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 1,134E-04 2,638E-03 ! myeloid leukocyte differentiation GO:0002573 46 25 2,000 1,134E-04 2,613E-03 ! negative regulation of DNA replication GO:0008156 45 25 2,000 1,134E-04 2,589E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 1,134E-04 2,565E-03 ! regulation of behavior GO:0050795 48 25 2,000 1,134E-04 2,541E-03 ! interaction with host GO:0051701 66 25 2,000 1,134E-04 2,518E-03 ! regulation of biomineral formation GO:0070167 56 25 2,000 1,134E-04 2,496E-03 ! protein tetramerization GO:0051262 57 25 2,000 1,134E-04 2,473E-03 ! molting cycle process GO:0022404 52 26 2,000 1,278E-04 2,764E-03 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 1,278E-04 2,739E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 1,381E-04 2,933E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 1,381E-04 2,908E-03 ! positive regulation of muscle development GO:0048636 15 5 1,000 1,4E-04 2,924E-03 GO:0045844|positive regulation of striated muscle development, ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 1,4E-04 2,899E-03 ! Notch receptor processing GO:0007220 11 5 1,000 1,4E-04 2,875E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 1,000 1,4E-04 2,851E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 1,4E-04 2,827E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 1,4E-04 2,804E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 1,4E-04 2,781E-03 ! valine metabolic process GO:0006573 12 5 1,000 1,4E-04 2,759E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 1,4E-04 2,737E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 1,4E-04 2,715E-03 ! muscle cell proliferation GO:0033002 12 5 1,000 1,4E-04 2,694E-03 ! B cell homeostasis GO:0001782 13 5 1,000 1,4E-04 2,673E-03 ! regulation of hair follicle development GO:0051797 10 5 1,000 1,4E-04 2,652E-03 GO:0042634|regulation of hair cycle, ! glial cell migration GO:0008347 10 5 1,000 1,4E-04 2,631E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 1,4E-04 2,611E-03 ! regulation of sensory perception GO:0051931 8 5 1,000 1,4E-04 2,592E-03 GO:0051930|regulation of sensory perception of pain, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 1,4E-04 2,572E-03 ! stem cell division GO:0017145 11 5 1,000 1,4E-04 2,553E-03 GO:0048103|somatic stem cell division, ! positive regulation of cell projection organization GO:0031346 66 27 2,000 1,434E-04 2,595E-03 ! mitochondrial membrane organization GO:0007006 60 27 2,000 1,434E-04 2,576E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 1,46E-04 2,604E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 1,602E-04 2,836E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 1,602E-04 2,815E-03 ! fat cell differentiation GO:0045444 57 28 2,000 1,602E-04 2,795E-03 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 1,782E-04 3,087E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 1,782E-04 3,065E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 1,782E-04 3,044E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 3,000 1,811E-04 3,073E-03 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,811E-04 3,052E-03 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 1,974E-04 3,303E-03 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 1,974E-04 3,281E-03 ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 1,000 2,095E-04 3,458E-03 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! neural nucleus development GO:0048857 19 6 1,000 2,095E-04 3,435E-03 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 2,095E-04 3,412E-03 ! salivary gland morphogenesis GO:0007435 14 6 1,000 2,095E-04 3,39E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 2,095E-04 3,367E-03 ! iron ion homeostasis GO:0055072 60 31 2,000 2,18E-04 3,481E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 2,18E-04 3,458E-03 ! metanephros development GO:0001656 81 32 2,000 2,399E-04 3,781E-03 ! BMP signaling pathway GO:0030509 71 32 2,000 2,399E-04 3,756E-03 ! hindbrain development GO:0030902 65 32 2,000 2,399E-04 3,732E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 3,000 2,446E-04 3,783E-03 ! response to hypoxia GO:0001666 178 81 3,000 2,566E-04 3,943E-03 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 2,566E-04 3,918E-03 ! response to ionizing radiation GO:0010212 74 33 2,000 2,631E-04 3,993E-03 ! response to oxygen levels GO:0070482 183 83 3,000 2,818E-04 4,249E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 2,818E-04 4,223E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 2,878E-04 4,287E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 2,878E-04 4,261E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 2,926E-04 4,306E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 2,926E-04 4,28E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 2,926E-04 4,255E-03 ! fibril organization GO:0043206 17 7 1,000 2,926E-04 4,23E-03 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 2,926E-04 4,205E-03 ! regulation of odontogenesis GO:0042481 14 7 1,000 2,926E-04 4,18E-03 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 2,926E-04 4,156E-03 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 1,000 2,926E-04 4,132E-03 ! microtubule nucleation GO:0007020 21 7 1,000 2,926E-04 4,108E-03 ! organ growth GO:0035265 15 7 1,000 2,926E-04 4,085E-03 ! male sex determination GO:0030238 15 7 1,000 2,926E-04 4,061E-03 ! wound healing, spreading of epidermal cells GO:0035313 16 7 1,000 2,926E-04 4,039E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 2,926E-04 4,016E-03 ! peptidyl-threonine modification GO:0018210 26 7 1,000 2,926E-04 3,993E-03 ! dopamine biosynthetic process GO:0042416 18 7 1,000 2,926E-04 3,971E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 2,926E-04 3,949E-03 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 3,139E-04 4,214E-03 ! mitochondrion organization GO:0007005 159 87 3,000 3,374E-04 4,504E-03 ! negative regulation of hydrolase activity GO:0051346 66 36 2,000 3,415E-04 4,534E-03 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 2,000 3,706E-04 4,894E-03 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! androgen receptor signaling pathway GO:0030521 81 37 2,000 3,706E-04 4,868E-03 ! positive regulation of protein modification process GO:0031401 156 90 3,000 3,839E-04 5,016E-03 ! succinate metabolic process GO:0006105 17 8 1,000 3,892E-04 5,057E-03 ! pigment granule organization GO:0048753 17 8 1,000 3,892E-04 5,03E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 3,892E-04 5,004E-03 ! regulation of pigmentation during development GO:0048070 25 8 1,000 3,892E-04 4,978E-03 ! melanin metabolic process GO:0006582 17 8 1,000 3,892E-04 4,952E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 1,000 3,892E-04 4,926E-03 ! response to UV-B GO:0010224 17 8 1,000 3,892E-04 4,901E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 3,892E-04 4,876E-03 ! response to tumor cell GO:0002347 16 8 1,000 3,892E-04 4,851E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 3,892E-04 4,826E-03 ! positive regulation of epidermis development GO:0045684 13 8 1,000 3,892E-04 4,802E-03 ! negative regulation of DNA replication initiation GO:0032297 10 8 1,000 3,892E-04 4,778E-03 GO:0000076|DNA replication checkpoint, ! DNA integrity checkpoint GO:0031570 82 38 2,000 4,013E-04 4,902E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 4,349E-04 5,286E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 4,991E-04 6,036E-03 ! regulation of glycolysis GO:0006110 20 9 1,000 4,991E-04 6,007E-03 ! middle ear morphogenesis GO:0042474 14 9 1,000 4,991E-04 5,977E-03 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 4,991E-04 5,948E-03 ! T cell selection GO:0045058 27 9 1,000 4,991E-04 5,919E-03 ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 4,991E-04 5,891E-03 ! regulation of telomere maintenance GO:0032204 17 9 1,000 4,991E-04 5,862E-03 ! regulation of hormone secretion GO:0046883 69 41 2,000 5,029E-04 5,878E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 2,000 5,029E-04 5,85E-03 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 5,029E-04 5,823E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 3,000 5,303E-04 6,111E-03 ! T cell differentiation GO:0030217 93 42 2,000 5,401E-04 6,195E-03 ! skeletal muscle tissue development GO:0007519 223 100 3,000 5,723E-04 6,534E-03 GO:0060538|skeletal muscle organ development, ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 6,197E-04 7,041E-03 ! regulation of developmental growth GO:0048638 16 10 1,000 6,224E-04 7,039E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 6,224E-04 7,007E-03 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 6,224E-04 6,974E-03 ! regulation of phosphatase activity GO:0010921 28 10 1,000 6,224E-04 6,943E-03 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 6,224E-04 6,911E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 6,224E-04 6,88E-03 ! positive regulation of heart contraction GO:0045823 17 10 1,000 6,224E-04 6,849E-03 ! phosphagen metabolic process GO:0006599 17 10 1,000 6,224E-04 6,818E-03 GO:0006600|creatine metabolic process, ! B cell proliferation GO:0042100 19 10 1,000 6,224E-04 6,788E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 6,224E-04 6,757E-03 ! protein heterooligomerization GO:0051291 17 10 1,000 6,224E-04 6,728E-03 ! regulation of gliogenesis GO:0014013 23 10 1,000 6,224E-04 6,698E-03 GO:0045685|regulation of glial cell differentiation, ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 6,224E-04 6,669E-03 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 6,224E-04 6,639E-03 ! salivary gland development GO:0007431 28 10 1,000 6,224E-04 6,611E-03 ! midbrain development GO:0030901 14 10 1,000 6,224E-04 6,582E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 6,224E-04 6,554E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 6,224E-04 6,525E-03 GO:0043470|regulation of carbohydrate catabolic process, ! response to nicotine GO:0035094 20 10 1,000 6,224E-04 6,498E-03 ! branching morphogenesis of a tube GO:0048754 102 45 2,000 6,621E-04 6,883E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 6,621E-04 6,854E-03 ! B cell differentiation GO:0030183 124 45 2,000 6,621E-04 6,825E-03 ! behavioral fear response GO:0001662 27 11 1,000 7,588E-04 7,789E-03 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 7,588E-04 7,756E-03 ! regulation of smoothened signaling pathway GO:0008589 27 11 1,000 7,588E-04 7,724E-03 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 7,588E-04 7,692E-03 ! regulation of intracellular pH GO:0051453 21 11 1,000 7,588E-04 7,66E-03 ! alpha-beta T cell activation GO:0046631 26 11 1,000 7,588E-04 7,628E-03 ! thymus development GO:0048538 29 11 1,000 7,588E-04 7,597E-03 ! oocyte development GO:0048599 20 11 1,000 7,588E-04 7,566E-03 ! cardiac cell differentiation GO:0035051 36 11 1,000 7,588E-04 7,535E-03 ! regulation of embryonic development GO:0045995 35 11 1,000 7,588E-04 7,505E-03 ! positive regulation of defense response GO:0031349 88 48 2,000 8,004E-04 7,885E-03 ! mitochondrial transport GO:0006839 94 48 2,000 8,004E-04 7,853E-03 ! regulation of inflammatory response GO:0050727 84 48 2,000 8,004E-04 7,822E-03 ! detection of stimulus involved in sensory perception GO:0050906 75 49 2,000 8,503E-04 8,276E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 9,021E-04 8,745E-03 ! activation of caspase activity GO:0006919 95 50 2,000 9,021E-04 8,71E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 9,083E-04 8,736E-03 ! virus-host interaction GO:0019048 30 12 1,000 9,083E-04 8,702E-03 ! regulation of B cell proliferation GO:0030888 22 12 1,000 9,083E-04 8,668E-03 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 1,000 9,083E-04 8,634E-03 ! focal adhesion formation GO:0048041 37 12 1,000 9,083E-04 8,601E-03 ! entry into host cell GO:0030260 34 12 1,000 9,083E-04 8,567E-03 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 9,083E-04 8,534E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 9,083E-04 8,502E-03 ! T cell homeostasis GO:0043029 28 12 1,000 9,083E-04 8,469E-03 ! oocyte differentiation GO:0009994 21 12 1,000 9,083E-04 8,437E-03 ! regulation of cell projection organization GO:0031344 135 51 2,000 9,558E-04 8,845E-03 ! detection of abiotic stimulus GO:0009582 80 51 2,000 9,558E-04 8,811E-03 ! morphogenesis of a branching structure GO:0001763 116 52 2,000 1,012E-03 9,29E-03 ! cartilage condensation GO:0001502 22 13 1,000 1,071E-03 9,798E-03 ! positive regulation of cell growth GO:0030307 24 13 1,000 1,071E-03 9,761E-03 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,071E-03 9,725E-03 ! plasma membrane organization GO:0007009 27 13 1,000 1,071E-03 9,689E-03 ! response to X-ray GO:0010165 28 13 1,000 1,071E-03 9,653E-03 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 1,071E-03 9,617E-03 ! exocrine system development GO:0035272 34 13 1,000 1,071E-03 9,582E-03 ! membrane protein proteolysis GO:0033619 33 13 1,000 1,071E-03 9,547E-03 GO:0006509|membrane protein ectodomain proteolysis, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,071E-03 9,513E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 1,071E-03 9,478E-03 ! regulation of epidermis development GO:0045682 19 13 1,000 1,071E-03 9,444E-03 ! spleen development GO:0048536 24 13 1,000 1,071E-03 9,41E-03 ! digestive tract morphogenesis GO:0048546 31 13 1,000 1,071E-03 9,376E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of muscle contraction GO:0006937 94 54 2,000 1,129E-03 9,851E-03 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 1,129E-03 9,816E-03 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 1,191E-03 0,0103174 ! fear response GO:0042596 34 14 1,000 1,246E-03 0,01075761 ! T cell differentiation in the thymus GO:0033077 37 14 1,000 1,246E-03 0,01071973 ! regulation of cellular pH GO:0030641 27 14 1,000 1,246E-03 0,01068211 ! positive regulation of bone mineralization GO:0030501 32 14 1,000 1,246E-03 0,01064476 ! catecholamine biosynthetic process GO:0042423 30 14 1,000 1,246E-03 0,01060767 ! skeletal muscle fiber development GO:0048741 130 56 2,000 1,255E-03 0,01064504 ! positive regulation of caspase activity GO:0043280 108 57 2,000 1,321E-03 0,01116686 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 2,000 1,321E-03 0,01112836 ! aging GO:0007568 112 58 2,000 1,389E-03 0,01166299 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 1,434E-03 0,01200036 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 1,434E-03 0,0119594 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 1,434E-03 0,01191872 ! glycoprotein catabolic process GO:0006516 33 15 1,000 1,434E-03 0,01187832 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 1,434E-03 0,01183819 ! G1/S transition checkpoint GO:0031575 37 15 1,000 1,434E-03 0,01179833 ! positive regulation of biomineral formation GO:0070169 33 15 1,000 1,434E-03 0,01175874 ! dopamine metabolic process GO:0042417 35 15 1,000 1,434E-03 0,01171941 ! lymphocyte homeostasis GO:0002260 33 15 1,000 1,434E-03 0,01168035 ! establishment of organelle localization GO:0051656 122 59 2,000 1,46E-03 0,01184702 ! kidney development GO:0001822 133 60 2,000 1,532E-03 0,01239521 ! positive regulation of secretion GO:0051047 110 61 2,000 1,607E-03 0,01295774 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,635E-03 0,01314083 ! positive regulation of cell size GO:0045793 29 16 1,000 1,635E-03 0,01309775 ! startle response GO:0001964 28 16 1,000 1,635E-03 0,01305495 ! regulation of dephosphorylation GO:0035303 43 16 1,000 1,635E-03 0,01301242 ! negative regulation of immune response GO:0050777 38 16 1,000 1,635E-03 0,01297017 ! DNA replication initiation GO:0006270 28 16 1,000 1,635E-03 0,0129282 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 1,635E-03 0,01288649 ! viral reproductive process GO:0022415 132 62 2,000 1,684E-03 0,01323002 ! regulation of homeostatic process GO:0032844 148 62 2,000 1,684E-03 0,01318762 ! regulation of protein complex assembly GO:0043254 132 63 2,000 1,764E-03 0,01376498 ! metencephalon development GO:0022037 32 17 1,000 1,849E-03 0,01438309 ! regulation of survival gene product expression GO:0045884 38 17 1,000 1,849E-03 0,01433743 ! regulation of protein binding GO:0043393 33 17 1,000 1,849E-03 0,01429206 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 1,849E-03 0,01424697 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 1,849E-03 0,01420217 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 1,849E-03 0,01415765 ! ear development GO:0043583 114 66 2,000 2,016E-03 0,01538775 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 2,016E-03 0,01533981 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 2,016E-03 0,01529217 ! regulation of viral genome replication GO:0045069 30 18 1,000 2,075E-03 0,01569134 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,075E-03 0,01564291 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 2,075E-03 0,01559478 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 1,000 2,075E-03 0,01554694 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 2,075E-03 0,0154994 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 2,075E-03 0,01545214 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 2,075E-03 0,01540517 ! defense response to virus GO:0051607 43 18 1,000 2,075E-03 0,01535849 ! activation of MAPK activity GO:0000187 124 67 2,000 2,104E-03 0,0155311 ! myeloid cell differentiation GO:0030099 126 67 2,000 2,104E-03 0,01548432 ! detection of external stimulus GO:0009581 102 68 2,000 2,195E-03 0,01610617 ! viral reproduction GO:0016032 142 68 2,000 2,195E-03 0,01605794 ! cell projection assembly GO:0030031 138 68 2,000 2,195E-03 0,01601001 ! lung development GO:0030324 165 69 2,000 2,289E-03 0,01664229 ! urogenital system development GO:0001655 149 69 2,000 2,289E-03 0,01659291 ! pigmentation during development GO:0048066 42 19 1,000 2,313E-03 0,01671779 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 1,000 2,313E-03 0,01666848 ! cellular pigmentation GO:0033059 37 19 1,000 2,313E-03 0,01661945 ! protein maturation by peptide bond cleavage GO:0051605 118 70 2,000 2,385E-03 0,01708568 ! cell cycle checkpoint GO:0000075 145 71 2,000 2,483E-03 0,01773867 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 2,483E-03 0,01768696 ! skin development GO:0043588 42 20 1,000 2,564E-03 0,01820637 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,564E-03 0,0181536 ! protein amino acid acetylation GO:0006473 41 20 1,000 2,564E-03 0,01810113 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 2,564E-03 0,01804897 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,564E-03 0,0179971 GO:0010675|regulation of cellular carbohydrate metabolic process, ! respiratory tube development GO:0030323 171 72 2,000 2,584E-03 0,01808909 ! B cell activation GO:0042113 179 72 2,000 2,584E-03 0,01803741 ! humoral immune response GO:0006959 115 73 2,000 2,688E-03 0,01870559 ! regulation of caspase activity GO:0043281 136 74 2,000 2,793E-03 0,01938747 ! respiratory system development GO:0060541 175 74 2,000 2,793E-03 0,01933255 ! organelle localization GO:0051640 155 74 2,000 2,793E-03 0,01927793 ! lipid phosphorylation GO:0046834 43 21 1,000 2,827E-03 0,01945128 ! ovarian follicle development GO:0001541 39 21 1,000 2,827E-03 0,01939664 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 2,827E-03 0,01934231 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 2,827E-03 0,01928828 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 2,827E-03 0,01923455 ! eye development GO:0001654 155 75 2,000 2,902E-03 0,01969256 ! lymphocyte differentiation GO:0030098 193 76 2,000 3,013E-03 0,02038921 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 3,102E-03 0,020931 ! cellular response to starvation GO:0009267 37 22 1,000 3,102E-03 0,02087334 ! apoptotic nuclear changes GO:0030262 34 22 1,000 3,102E-03 0,02081599 ! renal system process GO:0003014 42 22 1,000 3,102E-03 0,02075896 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,102E-03 0,02070224 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 3,102E-03 0,02064583 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,102E-03 0,02058973 ! response to cytokine stimulus GO:0034097 69 22 1,000 3,102E-03 0,02053393 ! gut development GO:0048565 44 22 1,000 3,102E-03 0,02047844 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 3,126E-03 0,02058757 ! protein oligomerization GO:0051259 149 79 2,000 3,361E-03 0,02207539 ! positive regulation of DNA replication GO:0045740 44 23 1,000 3,389E-03 0,02219361 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 3,389E-03 0,02213426 ! regeneration GO:0031099 42 23 1,000 3,389E-03 0,02207524 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 3,389E-03 0,02201653 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 1,000 3,389E-03 0,02195813 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 3,389E-03 0,02190004 ! activation of protein kinase activity GO:0032147 170 80 2,000 3,483E-03 0,02245042 ! muscle cell differentiation GO:0042692 178 81 2,000 3,607E-03 0,0231891 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 3,687E-03 0,02364451 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 3,687E-03 0,02358261 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 3,687E-03 0,02352104 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 3,687E-03 0,02345978 ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 3,687E-03 0,02339885 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 3,687E-03 0,02333823 ! sex determination GO:0007530 48 24 1,000 3,687E-03 0,02327793 ! regulation of viral reproduction GO:0050792 41 24 1,000 3,687E-03 0,02321793 ! oogenesis GO:0048477 44 24 1,000 3,687E-03 0,02315824 ! regulation of peptidase activity GO:0052547 150 82 2,000 3,734E-03 0,02338854 ! protein import into nucleus GO:0006606 174 82 2,000 3,734E-03 0,02332872 ! regulation of adenylate cyclase activity GO:0045761 165 83 2,000 3,863E-03 0,02407595 ! response to drug GO:0042493 149 83 2,000 3,863E-03 0,02401469 ! nuclear import GO:0051170 177 83 2,000 3,863E-03 0,02395374 ! response to metal ion GO:0010038 158 84 2,000 3,995E-03 0,02471045 ! T cell activation GO:0042110 189 84 2,000 3,995E-03 0,02464805 ! response to nutrient GO:0007584 135 84 2,000 3,995E-03 0,02458596 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 3,998E-03 0,02454226 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 3,998E-03 0,02448075 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 3,998E-03 0,02441955 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 3,998E-03 0,02435866 ! lymphocyte proliferation GO:0046651 55 25 1,000 3,998E-03 0,02429806 ! leukocyte homeostasis GO:0001776 50 25 1,000 3,998E-03 0,02423777 ! negative regulation of transport GO:0051051 164 85 2,000 4,13E-03 0,02497558 ! regulation of cyclase activity GO:0031279 168 85 2,000 4,13E-03 0,02491391 ! regulation of cAMP biosynthetic process GO:0030817 173 86 2,000 4,268E-03 0,02568062 ! regulation of lyase activity GO:0051339 169 86 2,000 4,268E-03 0,02561752 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 4,321E-03 0,02587201 ! initiation of viral infection GO:0019059 60 26 1,000 4,321E-03 0,02580876 ! multicellular organismal response to stress GO:0033555 61 26 1,000 4,321E-03 0,02574581 ! negative regulation of cell development GO:0010721 83 26 1,000 4,321E-03 0,02568317 GO:0050768|negative regulation of neurogenesis, ! positive regulation of MAPKKK cascade GO:0043410 50 26 1,000 4,321E-03 0,02562083 ! embryonic pattern specification GO:0009880 49 27 1,000 4,655E-03 0,02753563 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 4,655E-03 0,02746912 ! response to starvation GO:0042594 47 27 1,000 4,655E-03 0,02740293 ! response to toxin GO:0009636 49 27 1,000 4,655E-03 0,02733706 ! regulation of chromosome organization GO:0033044 49 27 1,000 4,655E-03 0,0272715 ! cellular response to nutrient levels GO:0031669 45 27 1,000 4,655E-03 0,02720626 ! leukocyte proliferation GO:0070661 59 27 1,000 4,655E-03 0,02714132 GO:0032943|mononuclear cell proliferation, ! regulation of cAMP metabolic process GO:0030814 182 89 2,000 4,697E-03 0,02732258 ! tube morphogenesis GO:0035239 194 89 2,000 4,697E-03 0,02725769 ! protein localization in nucleus GO:0034504 192 89 2,000 4,697E-03 0,02719309 ! response to inorganic substance GO:0010035 173 90 2,000 4,846E-03 0,02798782 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 2,000 4,998E-03 0,02879504 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 2,000 4,998E-03 0,02872729 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 5,001E-03 0,02867817 ! protein amino acid acylation GO:0043543 59 28 1,000 5,001E-03 0,028611 ! base-excision repair GO:0006284 41 28 1,000 5,001E-03 0,02854416 ! glutathione metabolic process GO:0006749 42 28 1,000 5,001E-03 0,02847762 ! regulation of cell adhesion GO:0030155 241 92 2,000 5,152E-03 0,02927039 ! catechol metabolic process GO:0009712 55 29 1,000 5,358E-03 0,03037033 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! response to organic cyclic substance GO:0014070 58 29 1,000 5,358E-03 0,03030003 ! somitogenesis GO:0001756 52 29 1,000 5,358E-03 0,03023005 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 5,358E-03 0,03016039 ! regulation of defense response GO:0031347 171 95 2,000 5,632E-03 0,0316314 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 2,000 5,632E-03 0,03155885 ! phenol metabolic process GO:0018958 56 30 1,000 5,727E-03 0,03201403 ! complement activation, classical pathway GO:0006958 51 30 1,000 5,727E-03 0,03194094 ! tissue homeostasis GO:0001894 50 30 1,000 5,727E-03 0,03186818 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 5,727E-03 0,03179576 ! regulation of protein localization GO:0032880 188 97 2,000 5,967E-03 0,03305478 ! cell junction assembly GO:0034329 85 31 1,000 6,107E-03 0,03375168 ! ovulation cycle process GO:0022602 55 31 1,000 6,107E-03 0,0336755 ! male gonad development GO:0008584 56 31 1,000 6,107E-03 0,03359965 ! eye morphogenesis GO:0048592 65 31 1,000 6,107E-03 0,03352414 ! response to heat GO:0009408 54 31 1,000 6,107E-03 0,03344898 ! regulation of nucleotide metabolic process GO:0006140 197 98 2,000 6,139E-03 0,03354939 ! positive regulation of immune response GO:0050778 175 100 2,000 6,491E-03 0,0353949 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 6,498E-03 0,03535351 ! collagen metabolic process GO:0032963 49 32 1,000 6,498E-03 0,03527495 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 1,000 6,498E-03 0,03519674 ! mesoderm formation GO:0001707 73 32 1,000 6,498E-03 0,03511887 ! ovulation cycle GO:0042698 57 32 1,000 6,498E-03 0,03504134 ! positive regulation of catabolic process GO:0009896 72 32 1,000 6,498E-03 0,03496416 ! regulation of pH GO:0006885 56 33 1,000 6,9E-03 0,03704696 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 6,9E-03 0,03696572 ! positive regulation of neurogenesis GO:0050769 72 33 1,000 6,9E-03 0,03688483 ! response to hydrogen peroxide GO:0042542 56 34 1,000 7,313E-03 0,03900862 ! post-embryonic development GO:0009791 76 34 1,000 7,313E-03 0,03892363 ! formation of primary germ layer GO:0001704 76 34 1,000 7,313E-03 0,03883902 ! adult locomotory behavior GO:0008344 62 34 1,000 7,313E-03 0,03875477 ! DNA damage checkpoint GO:0000077 78 35 1,000 7,737E-03 0,04091397 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 7,737E-03 0,04082561 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 7,737E-03 0,04073762 ! mesoderm morphogenesis GO:0048332 80 35 1,000 7,737E-03 0,04065001 ! biogenic amine biosynthetic process GO:0042401 65 35 1,000 7,737E-03 0,04056278 ! regulation of muscle development GO:0048634 82 36 1,000 8,172E-03 0,04275177 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 8,172E-03 0,04266042 ! odontogenesis GO:0042476 74 37 1,000 8,618E-03 0,04489168 ! cell junction organization GO:0034330 96 37 1,000 8,618E-03 0,04479617 ! female gonad development GO:0008585 71 37 1,000 8,618E-03 0,04470106 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 9,075E-03 0,0469691 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 9,075E-03 0,0468698 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 9,075E-03 0,04677092 ! regulation of protein stability GO:0031647 77 38 1,000 9,075E-03 0,04667245 ! glycogen metabolic process GO:0005977 63 38 1,000 9,075E-03 0,0465744 ! pigment metabolic process GO:0042440 87 38 1,000 9,075E-03 0,04647676 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 9,542E-03 0,04876677 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 9,542E-03 0,04866496 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 9,542E-03 0,04856357 ! glucan metabolic process GO:0044042 64 39 1,000 9,542E-03 0,04846261 GO:0006073|cellular glucan metabolic process, ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 1,000 0,01001936 0,05078275 GO:0006956|complement activation, ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01001936 0,05067761 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 1,000 0,01001936 0,05057291 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,01050738 0,05292686 ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01050738 0,05281796 ! gliogenesis GO:0042063 91 41 1,000 0,01050738 0,05270951 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,01100574 0,05509638 ! ear morphogenesis GO:0042471 64 42 1,000 0,01100574 0,05498371 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,01100574 0,0548715 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01151437 0,05729042 GO:0090047|positive regulation of transcription regulator activity, ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,01151437 0,05717397 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01151437 0,057058 ! segmentation GO:0035282 78 43 1,000 0,01151437 0,0569425 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,01203316 0,0593879 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01203316 0,05926817 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,01203316 0,05914892 ! double-strand break repair GO:0006302 85 44 1,000 0,01203316 0,05903014 ! female gamete generation GO:0007292 71 45 1,000 0,01256205 0,06150116 ! developmental growth GO:0048589 88 45 1,000 0,01256205 0,06137816 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01310094 0,06388344 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,01310094 0,06375618 ! cell growth GO:0016049 90 46 1,000 0,01310094 0,06362943 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01310094 0,06350318 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,01420843 0,06873505 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,01420843 0,06859921 ! cellular component disassembly GO:0022411 89 48 1,000 0,01420843 0,06846391 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,01420843 0,06832913 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,01420843 0,06819489 ! male sex differentiation GO:0046661 93 48 1,000 0,01420843 0,06806118 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,01420843 0,06792798 ! response to calcium ion GO:0051592 94 49 1,000 0,01477686 0,07050758 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,01477686 0,07037014 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,01535498 0,07298098 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 1,000 0,01535498 0,07283926 ! viral infectious cycle GO:0019058 104 51 1,000 0,0159427 0,07548067 ! peptide metabolic process GO:0006518 80 51 1,000 0,0159427 0,07533467 ! response to temperature stimulus GO:0009266 84 51 1,000 0,0159427 0,07518924 ! negative regulation of immune system process GO:0002683 101 51 1,000 0,0159427 0,07504436 ! positive regulation of binding GO:0051099 88 52 1,000 0,01653995 0,07770596 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,01653995 0,07755681 ! Notch signaling pathway GO:0007219 111 52 1,000 0,01653995 0,07740823 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,01653995 0,07726023 ! histone modification GO:0016570 104 52 1,000 0,01653995 0,07711278 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,01714664 0,07978904 ! vesicle organization GO:0016050 127 53 1,000 0,01714664 0,07963735 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,01714664 0,07948624 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! neuromuscular process GO:0050905 107 54 1,000 0,0177627 0,08218614 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,0177627 0,08203078 ! covalent chromatin modification GO:0016569 115 54 1,000 0,0177627 0,081876 ! cell maturation GO:0048469 107 55 1,000 0,01838805 0,08459889 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,01838805 0,08443987 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,01870933 0,08575402 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,01870933 0,08559343 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01870933 0,08543344 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,01870933 0,08527405 ! neuron fate determination GO:0048664 7 5 0,000 0,01870933 0,08511525 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01870933 0,08495704 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,01870933 0,08479942 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,01870933 0,08464239 ! polyol transport GO:0015791 12 5 0,000 0,01870933 0,08448593 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01870933 0,08433006 ! response to superoxide GO:0000303 10 5 0,000 0,01870933 0,08417475 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01870933 0,08402002 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,01870933 0,08386585 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,01870933 0,08371225 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01870933 0,08355921 ! female meiosis GO:0007143 10 5 0,000 0,01870933 0,08340673 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,01870933 0,08325481 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01870933 0,08310344 ! hypothalamus development GO:0021854 9 5 0,000 0,01870933 0,08295261 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,01870933 0,08280234 ! cobalt ion transport GO:0006824 11 5 0,000 0,01870933 0,0826526 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,01870933 0,08250341 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,01870933 0,08235476 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01870933 0,08220664 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01870933 0,08205905 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,01870933 0,08191199 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,01870933 0,08176546 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01870933 0,08161945 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01870933 0,08147396 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,01870933 0,08132899 ! transposition GO:0032196 9 5 0,000 0,01870933 0,08118453 ! negative chemotaxis GO:0050919 16 5 0,000 0,01870933 0,08104059 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,01870933 0,08089715 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01870933 0,08075422 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,01870933 0,0806118 ! behavioral response to pain GO:0048266 10 5 0,000 0,01870933 0,08046988 ! clathrin coat assembly GO:0048268 15 5 0,000 0,01870933 0,08032845 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01870933 0,08018753 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,01870933 0,08004709 ! micturition GO:0060073 9 5 0,000 0,01870933 0,07990715 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01870933 0,0797677 ! copulation GO:0007620 9 5 0,000 0,01870933 0,07962873 ! glial cell fate commitment GO:0021781 14 5 0,000 0,01870933 0,07949024 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,01870933 0,07935224 ! bioluminescence GO:0008218 9 5 0,000 0,01870933 0,07921471 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01870933 0,07907766 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01870933 0,07894109 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01870933 0,07880498 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,01870933 0,07866935 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01870933 0,07853418 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,01870933 0,07839947 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01870933 0,07826522 ! grooming behavior GO:0007625 6 5 0,000 0,01870933 0,07813144 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,01870933 0,07799811 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01870933 0,07786523 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01870933 0,07773281 ! response to protozoan GO:0001562 13 5 0,000 0,01870933 0,07760083 ! lymph vessel development GO:0001945 10 5 0,000 0,01870933 0,07746931 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,01870933 0,07733822 ! endochondral ossification GO:0001958 17 5 0,000 0,01870933 0,07720758 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01870933 0,07707739 ! single strand break repair GO:0000012 8 5 0,000 0,01870933 0,07694763 ! parathyroid gland development GO:0060017 14 5 0,000 0,01870933 0,0768183 ! anagen GO:0042640 7 5 0,000 0,01870933 0,07668941 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01870933 0,07656095 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01870933 0,07643293 ! cytokine secretion GO:0050663 15 5 0,000 0,01870933 0,07630533 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,01870933 0,07617815 ! ceramide catabolic process GO:0046514 7 5 0,000 0,01870933 0,0760514 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,01870933 0,07592507 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,01870933 0,07579915 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01870933 0,07567366 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01870933 0,07554858 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,01870933 0,07542391 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01870933 0,07529965 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01870933 0,07517581 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,01870933 0,07505236 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01870933 0,07492933 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,01870933 0,07480669 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01870933 0,07468446 ! microvillus organization GO:0032528 8 5 0,000 0,01870933 0,07456263 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,01870933 0,07444119 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,01870933 0,07432015 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,01870933 0,0741995 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,01870933 0,07407924 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,01870933 0,07395937 ! polyol catabolic process GO:0046174 9 5 0,000 0,01870933 0,07383989 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,01870933 0,07372079 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,01870933 0,07360208 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,01870933 0,07348375 ! muscle cell migration GO:0014812 8 5 0,000 0,01870933 0,07336579 ! mitochondrial fission GO:0000266 8 5 0,000 0,01870933 0,07324822 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,01870933 0,07313102 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,01870933 0,0730142 ! mRNA transcription GO:0009299 10 5 0,000 0,01870933 0,07289775 ! nerve growth factor processing GO:0032455 9 5 0,000 0,01870933 0,07278167 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,01870933 0,07266596 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,01870933 0,07255062 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,01870933 0,07243564 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01870933 0,07232103 ! monocyte activation GO:0042117 10 5 0,000 0,01870933 0,07220678 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01870933 0,07209289 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01870933 0,07197935 ! response to food GO:0032094 6 5 0,000 0,01870933 0,07186618 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01870933 0,07175336 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01870933 0,07164089 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,01870933 0,07152878 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01870933 0,07141702 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,01870933 0,0713056 ! forebrain neuron development GO:0021884 13 5 0,000 0,01870933 0,07119453 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01870933 0,07108381 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,01870933 0,07097343 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,01870933 0,0708634 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01870933 0,0707537 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01870933 0,07064434 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,01870933 0,07053532 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,01870933 0,07042664 ! lipid glycosylation GO:0030259 7 5 0,000 0,01870933 0,07031829 ! nucleobase transport GO:0015851 6 5 0,000 0,01870933 0,07021028 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01870933 0,07010259 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,01870933 0,06999524 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,01870933 0,06988821 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,01870933 0,06978151 ! basic amino acid transport GO:0015802 12 5 0,000 0,01870933 0,06967514 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,01870933 0,06956909 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,01870933 0,06946336 ! actin nucleation GO:0045010 11 5 0,000 0,01870933 0,06935795 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01870933 0,06925286 ! depurination GO:0045007 5 5 0,000 0,01870933 0,06914809 ! depyrimidination GO:0045008 10 5 0,000 0,01870933 0,06904364 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01870933 0,0689395 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01870933 0,06883568 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,01870933 0,06873217 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,01870933 0,06862896 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,01870933 0,06852607 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,01870933 0,06842349 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01870933 0,06832121 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01870933 0,06821924 ! activated T cell proliferation GO:0050798 16 5 0,000 0,01870933 0,06811757 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01870933 0,06801621 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,01870933 0,06791514 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01870933 0,06781438 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01870933 0,06771391 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,01870933 0,06761374 ! response to arsenic GO:0046685 11 5 0,000 0,01870933 0,06751387 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,01870933 0,06741429 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01870933 0,06731501 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,01870933 0,06721601 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,01870933 0,06711731 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,01870933 0,0670189 ! response to mercury ion GO:0046689 8 5 0,000 0,01870933 0,06692078 ! response to cadmium ion GO:0046686 7 5 0,000 0,01870933 0,06682294 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,01870933 0,06672539 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,01870933 0,06662812 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,01870933 0,06653114 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,01870933 0,06643443 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,01870933 0,06633801 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,01870933 0,06624187 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01870933 0,06614601 ! decidualization GO:0046697 11 5 0,000 0,01870933 0,06605042 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,01870933 0,06595511 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,01870933 0,06586007 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,01870933 0,06576531 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,01870933 0,06567082 ! embryonic cleavage GO:0040016 6 5 0,000 0,01870933 0,0655766 ! peroxisome fission GO:0016559 5 5 0,000 0,01870933 0,06548265 ! histone demethylation GO:0016577 13 5 0,000 0,01870933 0,06538897 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,01870933 0,06529556 ! mitotic recombination GO:0006312 9 5 0,000 0,01870933 0,06520241 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,01870933 0,06510953 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01870933 0,06501691 ! metaphase plate congression GO:0051310 7 5 0,000 0,01870933 0,06492456 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01870933 0,06483247 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01870933 0,06474064 ! enteric nervous system development GO:0048484 8 5 0,000 0,01870933 0,06464907 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,01870933 0,06455775 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,01870933 0,0644667 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,01870933 0,0643759 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01870933 0,06428536 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,01870933 0,06419507 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,01870933 0,06410504 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01870933 0,06401525 ! metaphase GO:0051323 11 5 0,000 0,01870933 0,06392572 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,01870933 0,06383644 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,01870933 0,06374741 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01870933 0,06365862 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01870933 0,06357008 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,01870933 0,06348179 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,01870933 0,06339374 ! definitive hemopoiesis GO:0060216 14 5 0,000 0,01870933 0,06330594 ! response to redox state GO:0051775 6 5 0,000 0,01870933 0,06321838 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,01870933 0,06313106 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,01870933 0,06304399 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01870933 0,06295715 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,01870933 0,06287055 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,01870933 0,06278419 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01870933 0,06269807 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,01870933 0,06261218 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01870933 0,06252653 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,01870933 0,06244111 ! striatum development GO:0021756 14 5 0,000 0,01870933 0,06235592 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,01870933 0,06227097 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01870933 0,06218624 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01870933 0,06210175 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,01870933 0,06201749 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01870933 0,06193346 ! T cell activation during immune response GO:0002286 9 5 0,000 0,01870933 0,06184965 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01870933 0,06176607 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01870933 0,06168271 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,01870933 0,06159958 ! neuroprotection GO:0043526 8 5 0,000 0,01870933 0,06151668 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01870933 0,06143399 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01870933 0,06135153 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,01870933 0,06126929 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,01870933 0,06118727 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01870933 0,06110547 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,01870933 0,06102389 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01870933 0,06094252 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,01870933 0,06086137 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,01870933 0,06078044 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,01870933 0,06069972 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01870933 0,06061922 ! spindle assembly GO:0051225 6 5 0,000 0,01870933 0,06053893 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01870933 0,06045885 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01870933 0,06037898 ! protein palmitoylation GO:0018345 12 5 0,000 0,01870933 0,06029933 ! drug metabolic process GO:0017144 7 5 0,000 0,01870933 0,06021988 ! phospholipid scrambling GO:0017121 8 5 0,000 0,01870933 0,06014064 ! organ regeneration GO:0031100 7 5 0,000 0,01870933 0,06006162 ! carnitine metabolic process GO:0009437 8 5 0,000 0,01870933 0,0599828 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01870933 0,05990418 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,01966631 0,06288585 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,01966631 0,06280364 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,01966631 0,06272165 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,02031906 0,06471898 ! gastrulation GO:0007369 122 58 1,000 0,02031906 0,06463471 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 1,000 0,02031906 0,06455066 ! lipid modification GO:0030258 112 60 1,000 0,02165143 0,06869408 ! DNA catabolic process GO:0006308 94 60 1,000 0,02165143 0,06860498 ! adult behavior GO:0030534 104 60 1,000 0,02165143 0,06851612 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,0223309 0,07057488 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02240929 0,07073113 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02240929 0,07063987 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02240929 0,07054884 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02240929 0,07045804 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02240929 0,07036748 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02240929 0,07027715 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02240929 0,07018705 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02240929 0,07009718 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02240929 0,07000754 ! response to oxygen radical GO:0000305 11 6 0,000 0,02240929 0,06991813 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02240929 0,06982895 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02240929 0,06974 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02240929 0,06965127 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02240929 0,06956277 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02240929 0,06947449 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02240929 0,06938644 ! forebrain regionalization GO:0021871 9 6 0,000 0,02240929 0,0692986 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02240929 0,069211 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02240929 0,06912361 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02240929 0,06903644 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02240929 0,06894949 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02240929 0,06886276 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02240929 0,06877625 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02240929 0,06868996 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02240929 0,06860388 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02240929 0,06851802 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02240929 0,06843237 ! malate metabolic process GO:0006108 13 6 0,000 0,02240929 0,06834694 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02240929 0,06826172 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02240929 0,06817671 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02240929 0,06809191 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02240929 0,06800733 ! protein refolding GO:0042026 15 6 0,000 0,02240929 0,06792295 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02240929 0,06783878 ! opsonization GO:0008228 8 6 0,000 0,02240929 0,06775482 ! mating behavior GO:0007617 7 6 0,000 0,02240929 0,06767107 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02240929 0,06758753 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02240929 0,06750419 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02240929 0,06742106 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02240929 0,06733813 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02240929 0,0672554 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02240929 0,06717288 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02240929 0,06709056 ! toxin metabolic process GO:0009404 11 6 0,000 0,02240929 0,06700844 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02240929 0,06692652 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02240929 0,06684481 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02240929 0,06676329 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02240929 0,06668197 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02240929 0,06660085 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02240929 0,06651992 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02240929 0,0664392 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02240929 0,06635866 ! thymic T cell selection GO:0045061 16 6 0,000 0,02240929 0,06627833 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02240929 0,06619818 ! protein lipoylation GO:0009249 10 6 0,000 0,02240929 0,06611823 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02240929 0,06603848 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02240929 0,06595891 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02240929 0,06587954 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02240929 0,06580036 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02240929 0,06572137 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02240929 0,06564256 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02240929 0,06556395 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02240929 0,06548552 ! hyperosmotic response GO:0006972 10 6 0,000 0,02240929 0,06540728 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02240929 0,06532923 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02240929 0,06525137 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02240929 0,06517369 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02240929 0,06509619 ! urea metabolic process GO:0019627 7 6 0,000 0,02240929 0,06501888 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02240929 0,06494175 ! neutrophil activation GO:0042119 7 6 0,000 0,02240929 0,06486481 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02240929 0,06478804 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02240929 0,06471146 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02240929 0,06463506 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02240929 0,06455884 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02240929 0,0644828 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02240929 0,06440694 ! neuron apoptosis GO:0051402 15 6 0,000 0,02240929 0,06433125 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02240929 0,06425575 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02240929 0,06418042 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02240929 0,06410527 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02240929 0,06403029 ! carnitine transport GO:0015879 10 6 0,000 0,02240929 0,06395549 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02240929 0,06388086 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02240929 0,06380641 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02240929 0,06373213 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02240929 0,06365802 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02240929 0,06358409 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02240929 0,06351032 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02240929 0,06343673 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02240929 0,06336331 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02240929 0,06329005 ! establishment of spindle localization GO:0051293 16 6 0,000 0,02240929 0,06321697 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02240929 0,06314406 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02240929 0,06307131 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,02240929 0,06299873 ! astrocyte development GO:0014002 16 6 0,000 0,02240929 0,06292632 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02240929 0,06285407 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02240929 0,06278199 ! interaction with symbiont GO:0051702 14 6 0,000 0,02240929 0,06271008 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02240929 0,06263833 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02240929 0,06256674 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02240929 0,06249532 ! response to copper ion GO:0046688 10 6 0,000 0,02240929 0,06242406 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02240929 0,06235296 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02240929 0,06228202 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02240929 0,06221125 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02240929 0,06214063 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02240929 0,06207018 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02240929 0,06199988 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02240929 0,06192975 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02240929 0,06185977 ! hair follicle maturation GO:0048820 8 6 0,000 0,02240929 0,06178995 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02240929 0,06172029 ! Schwann cell development GO:0014044 15 6 0,000 0,02240929 0,06165079 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02240929 0,06158144 ! response to pheromone GO:0019236 6 6 0,000 0,02240929 0,06151224 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02240929 0,06144321 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02240929 0,06137432 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02240929 0,0613056 ! subpallium development GO:0021544 15 6 0,000 0,02240929 0,06123702 ! neural tube patterning GO:0021532 8 6 0,000 0,02240929 0,0611686 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02240929 0,06110033 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02240929 0,06103222 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02240929 0,06096425 ! G2 phase GO:0051319 16 6 0,000 0,02240929 0,06089644 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02240929 0,06082877 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02240929 0,06076126 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02240929 0,0606939 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02240929 0,06062669 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02240929 0,06055962 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02240929 0,0604927 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02240929 0,06042594 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02240929 0,06035931 ! receptor internalization GO:0031623 11 6 0,000 0,02240929 0,06029284 ! plasminogen activation GO:0031639 9 6 0,000 0,02240929 0,06022651 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02240929 0,06016033 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02240929 0,06009429 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 16 6 0,000 0,02240929 0,0600284 ! protein destabilization GO:0031648 9 6 0,000 0,02240929 0,05996265 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02240929 0,05989704 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02240929 0,05983158 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02240929 0,05976626 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02240929 0,05970109 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02240929 0,05963605 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02240929 0,05957116 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02240929 0,05950641 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02240929 0,0594418 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02240929 0,05937733 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02240929 0,059313 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02240929 0,05924881 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02240929 0,05918475 ! neural plate development GO:0001840 9 6 0,000 0,02240929 0,05912084 ! catecholamine transport GO:0051937 9 6 0,000 0,02240929 0,05905706 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02240929 0,05899342 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02240929 0,05892992 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02240929 0,05886656 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02240929 0,05880333 ! maternal placenta development GO:0001893 12 6 0,000 0,02240929 0,05874023 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02240929 0,05867727 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02240929 0,05861445 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,02240929 0,05855176 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02240929 0,05848921 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02240929 0,05842678 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02240929 0,0583645 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02240929 0,05830234 GO:0055081|anion homeostasis, ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,02301912 0,05982523 ! mesoderm development GO:0007498 128 63 1,000 0,02371602 0,06157093 ! protein amino acid autophosphorylation GO:0046777 157 64 1,000 0,02442153 0,06333525 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,02513557 0,06511793 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,02513557 0,06504895 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,02513557 0,06498011 GO:0048609|reproductive process in a multicellular organism, ! gonad development GO:0008406 115 66 1,000 0,02585807 0,06677724 ! tRNA transcription GO:0009304 17 7 0,000 0,02609541 0,06731898 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02609541 0,06724797 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02609541 0,06717711 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02609541 0,0671064 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02609541 0,06703583 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02609541 0,06696542 ! sleep GO:0030431 16 7 0,000 0,02609541 0,06689515 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02609541 0,06682503 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02609541 0,06675505 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02609541 0,06668523 ! prostate gland development GO:0030850 14 7 0,000 0,02609541 0,06661554 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02609541 0,06654601 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02609541 0,06647662 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02609541 0,06640737 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02609541 0,06633827 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02609541 0,06626931 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02609541 0,06620049 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02609541 0,06613182 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02609541 0,06606329 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02609541 0,0659949 ! glycolipid transport GO:0046836 11 7 0,000 0,02609541 0,06592666 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02609541 0,06585855 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02609541 0,06579058 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02609541 0,06572276 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02609541 0,06565507 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02609541 0,06558753 ! mRNA stabilization GO:0048255 18 7 0,000 0,02609541 0,06552012 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02609541 0,06545285 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02609541 0,06538572 GO:0031958|corticosteroid receptor signaling pathway, ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,02609541 0,06531873 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02609541 0,06525187 ! lipoprotein transport GO:0042953 14 7 0,000 0,02609541 0,06518515 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02609541 0,06511857 ! rhythmic behavior GO:0007622 17 7 0,000 0,02609541 0,06505212 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02609541 0,06498581 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02609541 0,06491963 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02609541 0,06485359 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02609541 0,06478768 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02609541 0,0647219 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02609541 0,06465626 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02609541 0,06459076 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02609541 0,06452538 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02609541 0,06446014 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02609541 0,06439503 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02609541 0,06433005 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02609541 0,0642652 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02609541 0,06420048 ! spinal cord patterning GO:0021511 14 7 0,000 0,02609541 0,06413589 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02609541 0,06407143 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02609541 0,0640071 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02609541 0,0639429 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02609541 0,06387883 ! adrenal gland development GO:0030325 17 7 0,000 0,02609541 0,06381489 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02609541 0,06375108 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02609541 0,06368739 ! ovulation GO:0030728 10 7 0,000 0,02609541 0,06362383 ! adenohypophysis development GO:0021984 11 7 0,000 0,02609541 0,0635604 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02609541 0,06349709 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02609541 0,06343391 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline biosynthetic process GO:0006561 10 7 0,000 0,02609541 0,06337085 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02609541 0,06330792 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02609541 0,06324512 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02609541 0,06318243 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02609541 0,06311988 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02609541 0,06305744 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02609541 0,06299513 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02609541 0,06293295 ! galactose metabolic process GO:0006012 13 7 0,000 0,02609541 0,06287088 ! vesicle fusion GO:0006906 20 7 0,000 0,02609541 0,06280894 ! response to dietary excess GO:0002021 8 7 0,000 0,02609541 0,06274712 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02609541 0,06268542 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02609541 0,06262385 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02609541 0,06256239 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02609541 0,06250106 ! nucleoside transport GO:0015858 11 7 0,000 0,02609541 0,06243984 ! nucleoside salvage GO:0043174 11 7 0,000 0,02609541 0,06237874 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02609541 0,06231777 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02609541 0,06225691 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02609541 0,06219617 ! parturition GO:0007567 16 7 0,000 0,02609541 0,06213555 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02609541 0,06207505 ! rRNA modification GO:0000154 14 7 0,000 0,02609541 0,06201467 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02609541 0,0619544 ! spindle checkpoint GO:0031577 16 7 0,000 0,02609541 0,06189425 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02609541 0,06183422 ! monocyte differentiation GO:0030224 16 7 0,000 0,02609541 0,0617743 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02609541 0,0617145 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02609541 0,06165481 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02609541 0,06159524 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02609541 0,06153579 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02609541 0,06147645 ! fibrinolysis GO:0042730 11 7 0,000 0,02609541 0,06141722 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,02609541 0,06135811 ! eating behavior GO:0042755 8 7 0,000 0,02609541 0,06129911 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02609541 0,06124023 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02609541 0,06118146 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02609541 0,0611228 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02609541 0,06106425 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02609541 0,06100581 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02609541 0,06094749 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02609541 0,06088928 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02609541 0,06083118 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02609541 0,06077319 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02609541 0,06071531 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02609541 0,06065754 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02609541 0,06059988 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02609541 0,06054233 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02609541 0,06048489 ! histone ubiquitination GO:0016574 9 7 0,000 0,02609541 0,06042756 ! regulation of meiosis GO:0040020 12 7 0,000 0,02609541 0,06037034 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02609541 0,06031322 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02609541 0,06025622 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02609541 0,06019932 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02609541 0,06014252 ! transcription termination GO:0006353 14 7 0,000 0,02609541 0,06008584 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02609541 0,06002926 ! anaphase GO:0051322 18 7 0,000 0,02609541 0,05997279 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,02609541 0,05991643 ! axonal fasciculation GO:0007413 19 7 0,000 0,02609541 0,05986017 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02609541 0,05980401 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02609541 0,05974796 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02609541 0,05969202 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,02609541 0,05963618 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02609541 0,05958045 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02609541 0,05952481 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02609541 0,05946929 ! antibiotic transport GO:0042891 9 7 0,000 0,02609541 0,05941386 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02609541 0,05935854 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02609541 0,05930333 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02609541 0,05924821 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02609541 0,0591932 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02609541 0,05913829 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02609541 0,05908348 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02609541 0,05902877 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02609541 0,05897417 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02609541 0,05891966 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02609541 0,05886526 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02609541 0,05881096 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02609541 0,05875675 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02609541 0,05870265 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02609541 0,05864864 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02609541 0,05859474 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02609541 0,05854093 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02609541 0,05848723 ! muscle adaptation GO:0043500 13 7 0,000 0,02609541 0,05843362 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02609541 0,05838011 ! retina homeostasis GO:0001895 12 7 0,000 0,02609541 0,05832669 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02609541 0,05827338 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02609541 0,05822016 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02609541 0,05816704 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02609541 0,05811402 ! chromosome segregation GO:0007059 127 67 1,000 0,02658896 0,05915922 ! secondary metabolic process GO:0019748 125 67 1,000 0,02658896 0,05910539 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,02732816 0,06069335 ! adaptive immune response GO:0002250 126 68 1,000 0,02732816 0,06063823 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! homeostasis of number of cells GO:0048872 131 69 1,000 0,0280756 0,06224018 ! developmental maturation GO:0021700 128 69 1,000 0,0280756 0,06218376 ! germ cell development GO:0007281 133 70 1,000 0,02883121 0,06379949 ! activation of immune response GO:0002253 120 70 1,000 0,02883121 0,06374175 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02976773 0,06575276 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02976773 0,06569336 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 0,000 0,02976773 0,06563407 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02976773 0,06557489 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02976773 0,06551581 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02976773 0,06545684 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02976773 0,06539798 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02976773 0,06533922 ! male meiosis GO:0007140 9 8 0,000 0,02976773 0,06528057 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02976773 0,06522202 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02976773 0,06516358 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02976773 0,06510524 ! meiotic prophase I GO:0007128 14 8 0,000 0,02976773 0,06504701 ! response to zinc ion GO:0010043 12 8 0,000 0,02976773 0,06498888 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02976773 0,06493085 ! oligopeptide transport GO:0006857 16 8 0,000 0,02976773 0,06487293 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02976773 0,06481511 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02976773 0,06475739 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02976773 0,06469978 ! signal peptide processing GO:0006465 12 8 0,000 0,02976773 0,06464227 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02976773 0,06458486 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02976773 0,06452755 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02976773 0,06447035 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02976773 0,06441324 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02976773 0,06435624 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02976773 0,06429934 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02976773 0,06424254 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02976773 0,06418584 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02976773 0,06412924 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02976773 0,06407273 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02976773 0,06401633 ! reflex GO:0060004 17 8 0,000 0,02976773 0,06396003 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02976773 0,06390382 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02976773 0,06384772 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02976773 0,06379171 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02976773 0,0637358 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02976773 0,06367999 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02976773 0,06362428 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02976773 0,06356866 ! histidine catabolic process GO:0006548 10 8 0,000 0,02976773 0,06351315 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02976773 0,06345772 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02976773 0,0634024 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02976773 0,06334717 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02976773 0,06329204 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02976773 0,063237 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02976773 0,06318206 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02976773 0,06312722 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02976773 0,06307247 ! macrophage activation GO:0042116 13 8 0,000 0,02976773 0,06301781 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02976773 0,06296325 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02976773 0,06290878 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02976773 0,06285441 ! purine salvage GO:0043101 12 8 0,000 0,02976773 0,06280013 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02976773 0,06274595 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02976773 0,06269186 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02976773 0,06263786 ! osteoblast development GO:0002076 17 8 0,000 0,02976773 0,06258395 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02976773 0,06253014 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02976773 0,06247642 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02976773 0,06242279 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02976773 0,06236926 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02976773 0,06231581 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02976773 0,06226246 ! intermediate filament organization GO:0045109 12 8 0,000 0,02976773 0,0622092 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02976773 0,06215603 ! cellular extravasation GO:0045123 13 8 0,000 0,02976773 0,06210295 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02976773 0,06204996 ! response to antibiotic GO:0046677 11 8 0,000 0,02976773 0,06199706 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02976773 0,06194425 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02976773 0,06189153 ! DNA topological change GO:0006265 12 8 0,000 0,02976773 0,06183891 ! response to tropane GO:0014073 15 8 0,000 0,02976773 0,06178637 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,02976773 0,06173392 ! melanosome transport GO:0032402 13 8 0,000 0,02976773 0,06168155 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02976773 0,06162928 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02976773 0,0615771 ! mast cell activation GO:0045576 14 8 0,000 0,02976773 0,061525 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02976773 0,06147299 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02976773 0,06142107 ! gas homeostasis GO:0033483 14 8 0,000 0,02976773 0,06136924 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02976773 0,0613175 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02976773 0,06126584 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02976773 0,06121427 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02976773 0,06116279 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02976773 0,06111139 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02976773 0,06106008 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02976773 0,06100885 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02976773 0,06095771 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02976773 0,06090666 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02976773 0,06085569 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02976773 0,06080481 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02976773 0,06075401 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02976773 0,0607033 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02976773 0,06065267 ! hormone catabolic process GO:0042447 17 8 0,000 0,02976773 0,06060213 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02976773 0,06055167 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02976773 0,06050129 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02976773 0,060451 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02976773 0,06040079 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02976773 0,06035067 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02976773 0,06030062 ! adult feeding behavior GO:0008343 10 8 0,000 0,02976773 0,06025066 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02976773 0,06020079 ! ATP catabolic process GO:0006200 11 8 0,000 0,02976773 0,06015099 ! blastocyst growth GO:0001832 19 8 0,000 0,02976773 0,06010128 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02976773 0,06005165 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02976773 0,06000211 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02976773 0,05995264 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02976773 0,05990326 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02976773 0,05985395 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02976773 0,05980473 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02976773 0,05975559 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02976773 0,05970653 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02976773 0,05965755 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02976773 0,05960865 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02976773 0,05955983 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02976773 0,05951109 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02976773 0,05946243 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02976773 0,05941385 ! protein prenylation GO:0018342 21 8 0,000 0,02976773 0,05936535 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02976773 0,05931693 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02976773 0,05926858 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02976773 0,05922032 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02976773 0,05917213 ! actin filament organization GO:0007015 167 72 1,000 0,03036665 0,0603136 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,03036665 0,0602646 ! acute inflammatory response GO:0002526 118 74 1,000 0,03193392 0,06332352 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,03272932 0,06484812 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,03272932 0,06479557 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,03272932 0,06474311 ! rhythmic process GO:0048511 142 75 1,000 0,03272932 0,06469073 ! axon extension GO:0048675 16 9 0,000 0,0334263 0,06601492 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0334263 0,06596159 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0334263 0,06590835 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0334263 0,0658552 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0334263 0,06580214 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0334263 0,06574916 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0334263 0,06569626 ! reproductive behavior GO:0019098 22 9 0,000 0,0334263 0,06564345 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0334263 0,06559072 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0334263 0,06553808 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0334263 0,06548553 ! UTP metabolic process GO:0046051 10 9 0,000 0,0334263 0,06543305 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0334263 0,06538067 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0334263 0,06532836 ! artery development GO:0060840 25 9 0,000 0,0334263 0,06527614 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0334263 0,065224 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0334263 0,06517195 ! equilibrioception GO:0050957 20 9 0,000 0,0334263 0,06511998 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0334263 0,06506809 ! chemosensory behavior GO:0007635 21 9 0,000 0,0334263 0,06501628 ! microtubule bundle formation GO:0001578 22 9 0,000 0,0334263 0,06496456 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0334263 0,06491292 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0334263 0,06486136 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0334263 0,06480988 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0334263 0,06475849 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0334263 0,06470717 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0334263 0,06465594 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0334263 0,06460479 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0334263 0,06455372 ! protein targeting to ER GO:0045047 25 9 0,000 0,0334263 0,06450273 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0334263 0,06445182 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0334263 0,06440099 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0334263 0,06435024 ! glycine catabolic process GO:0006546 15 9 0,000 0,0334263 0,06429957 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0334263 0,06424898 ! endosome organization GO:0007032 20 9 0,000 0,0334263 0,06419847 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0334263 0,06414804 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0334263 0,06409769 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0334263 0,06404741 ! mannose metabolic process GO:0006013 13 9 0,000 0,0334263 0,06399722 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0334263 0,0639471 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0334263 0,06389707 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0334263 0,06384711 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0334263 0,06379723 ! receptor clustering GO:0043113 20 9 0,000 0,0334263 0,06374743 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0334263 0,0636977 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0334263 0,06364805 ! retinol metabolic process GO:0042572 20 9 0,000 0,0334263 0,06359848 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0334263 0,06354899 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0334263 0,06349957 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0334263 0,06345023 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0334263 0,06340097 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0334263 0,06335179 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0334263 0,06330268 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0334263 0,06325364 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0334263 0,06320468 ! response to amine stimulus GO:0014075 13 9 0,000 0,0334263 0,0631558 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0334263 0,063107 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0334263 0,06305826 ! erythrocyte development GO:0048821 17 9 0,000 0,0334263 0,06300961 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0334263 0,06296103 ! renal water homeostasis GO:0003091 15 9 0,000 0,0334263 0,06291252 ! postreplication repair GO:0006301 25 9 0,000 0,0334263 0,06286409 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0334263 0,06281573 ! icosanoid secretion GO:0032309 15 9 0,000 0,0334263 0,06276745 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0334263 0,06271924 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0334263 0,06267111 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0334263 0,06262305 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0334263 0,06257506 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0334263 0,06252715 ! sterol catabolic process GO:0016127 14 9 0,000 0,0334263 0,0624793 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0334263 0,06243154 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0334263 0,06238384 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0334263 0,06233622 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0334263 0,06228867 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,0334263 0,0622412 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0334263 0,06219379 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0334263 0,06214646 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0334263 0,0620992 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0334263 0,06205201 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0334263 0,0620049 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0334263 0,06195785 ! purine base metabolic process GO:0006144 25 9 0,000 0,0334263 0,06191088 ! pigment granule transport GO:0051904 17 9 0,000 0,0334263 0,06186398 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0334263 0,06181715 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0334263 0,06177039 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0334263 0,0617237 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0334263 0,06167708 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0334263 0,06163053 ! mitochondrion localization GO:0051646 18 9 0,000 0,0334263 0,06158405 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,03353247 0,0617331 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,0343433 0,06317822 ! regulation of catabolic process GO:0009894 173 77 1,000 0,0343433 0,06313068 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,03516173 0,06458655 ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,03598772 0,06605409 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,03682117 0,06753313 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,03707118 0,06794066 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03707118 0,06788973 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03707118 0,06783887 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03707118 0,0677881 ! associative learning GO:0008306 21 10 0,000 0,03707118 0,0677374 ! phosphate transport GO:0006817 24 10 0,000 0,03707118 0,06768677 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03707118 0,06763622 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03707118 0,06758574 ! CTP metabolic process GO:0046036 11 10 0,000 0,03707118 0,06753535 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,03707118 0,06748502 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03707118 0,06743477 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03707118 0,0673846 ! social behavior GO:0035176 29 10 0,000 0,03707118 0,0673345 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03707118 0,06728447 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03707118 0,06723452 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03707118 0,06718464 ! androgen metabolic process GO:0008209 17 10 0,000 0,03707118 0,06713484 ! phospholipid efflux GO:0033700 19 10 0,000 0,03707118 0,06708511 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03707118 0,06703545 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03707118 0,06698587 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03707118 0,06693636 ! lung alveolus development GO:0048286 26 10 0,000 0,03707118 0,06688693 ! pathogenesis GO:0009405 17 10 0,000 0,03707118 0,06683756 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03707118 0,06678827 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03707118 0,06673906 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03707118 0,06668991 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03707118 0,06664084 ! endoderm development GO:0007492 18 10 0,000 0,03707118 0,06659184 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03707118 0,06654291 ! arginine catabolic process GO:0006527 17 10 0,000 0,03707118 0,06649405 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03707118 0,06644527 ! proline metabolic process GO:0006560 13 10 0,000 0,03707118 0,06639655 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03707118 0,06634791 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03707118 0,06629934 ! V(D)J recombination GO:0033151 34 10 0,000 0,03707118 0,06625084 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03707118 0,06620241 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03707118 0,06615405 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03707118 0,06610576 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03707118 0,06605755 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03707118 0,0660094 ! multicellular organism growth GO:0035264 19 10 0,000 0,03707118 0,06596132 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03707118 0,06591332 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03707118 0,06586538 ! ruffle organization GO:0031529 17 10 0,000 0,03707118 0,06581751 ! epithelial cell development GO:0002064 21 10 0,000 0,03707118 0,06576972 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03707118 0,06572199 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03707118 0,06567433 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03707118 0,06562674 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03707118 0,06557922 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03707118 0,06553176 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03707118 0,06548438 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 22 10 0,000 0,03707118 0,06543706 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03707118 0,06538982 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03707118 0,06534264 ! brain morphogenesis GO:0048854 23 10 0,000 0,03707118 0,06529553 ! segment specification GO:0007379 15 10 0,000 0,03707118 0,06524849 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03707118 0,06520151 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03707118 0,0651546 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03707118 0,06510776 ! response to dsRNA GO:0043331 23 10 0,000 0,03707118 0,06506099 ! DNA ligation GO:0006266 18 10 0,000 0,03707118 0,06501428 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03707118 0,06496765 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03707118 0,06492107 ! melanosome localization GO:0032400 16 10 0,000 0,03707118 0,06487457 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03707118 0,06482813 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,03707118 0,06478176 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03707118 0,06473545 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03707118 0,06468921 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03707118 0,06464304 ! induction of an organ GO:0001759 17 10 0,000 0,03707118 0,06459693 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03707118 0,06455089 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03707118 0,06450491 ! protein sumoylation GO:0016925 17 10 0,000 0,03707118 0,064459 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03707118 0,06441316 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03707118 0,06436738 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03707118 0,06432166 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03707118 0,06427601 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03707118 0,06423042 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03707118 0,0641849 ! musculoskeletal movement GO:0050881 16 10 0,000 0,03707118 0,06413945 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03707118 0,06409405 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03707118 0,06404873 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03707118 0,06400346 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03707118 0,06395826 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03707118 0,06391312 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03707118 0,06386805 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03707118 0,06382304 ! detection of calcium ion GO:0005513 24 10 0,000 0,03707118 0,0637781 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03707118 0,06373321 ! blastocyst formation GO:0001825 18 10 0,000 0,03707118 0,0636884 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03707118 0,06364364 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03707118 0,06359895 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03707118 0,06355431 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03707118 0,06350975 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03707118 0,06346524 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03707118 0,0634208 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,03851025 0,06583662 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04070242 0,06953568 ! respiratory burst GO:0045730 17 11 0,000 0,04070242 0,06948708 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04070242 0,06943856 ! neuron fate specification GO:0048665 18 11 0,000 0,04070242 0,0693901 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04070242 0,06934171 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04070242 0,06929339 ! thyroid gland development GO:0030878 26 11 0,000 0,04070242 0,06924514 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,04070242 0,06919695 ! synapsis GO:0007129 14 11 0,000 0,04070242 0,06914883 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04070242 0,06910078 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04070242 0,06905279 ! response to pain GO:0048265 27 11 0,000 0,04070242 0,06900487 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,04070242 0,06895702 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04070242 0,06890923 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,04070242 0,06886151 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,04070242 0,06881385 ! bone resorption GO:0045453 16 11 0,000 0,04070242 0,06876626 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04070242 0,06871874 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04070242 0,06867128 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04070242 0,06862389 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04070242 0,06857656 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04070242 0,0685293 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04070242 0,0684821 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04070242 0,06843497 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04070242 0,06838791 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04070242 0,0683409 ! UV protection GO:0009650 20 11 0,000 0,04070242 0,06829397 ! adult heart development GO:0007512 16 11 0,000 0,04070242 0,06824709 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04070242 0,06820029 ! macroautophagy GO:0016236 19 11 0,000 0,04070242 0,06815354 ! temperature homeostasis GO:0001659 18 11 0,000 0,04070242 0,06810686 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04070242 0,06806024 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04070242 0,06801369 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04070242 0,0679672 ! regulation of organ growth GO:0046620 14 11 0,000 0,04070242 0,06792078 ! pigment granule localization GO:0051875 20 11 0,000 0,04070242 0,06787441 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04070242 0,06782811 ! vasoconstriction GO:0042310 20 11 0,000 0,04070242 0,06778188 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04070242 0,06773571 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04070242 0,0676896 ! embryonic axis specification GO:0000578 19 11 0,000 0,04070242 0,06764355 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04070242 0,06759756 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04070242 0,06755164 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04070242 0,06750578 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04070242 0,06745998 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04070242 0,06741425 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04070242 0,06736857 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04070242 0,06732296 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04070242 0,06727741 ! prophase GO:0051324 17 11 0,000 0,04070242 0,06723192 ! neuroblast proliferation GO:0007405 25 11 0,000 0,04070242 0,0671865 ! nucleosome positioning GO:0016584 15 11 0,000 0,04070242 0,06714113 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04070242 0,06709583 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04070242 0,06705058 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04070242 0,0670054 ! apical protein localization GO:0045176 18 11 0,000 0,04070242 0,06696028 ! acid secretion GO:0046717 20 11 0,000 0,04070242 0,06691522 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04070242 0,06687022 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04070242 0,06682528 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,04070242 0,0667804 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04070242 0,06673558 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04070242 0,06669082 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04070242 0,06664612 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,04070242 0,06660148 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04070242 0,0665569 ! germ cell migration GO:0008354 26 11 0,000 0,04070242 0,06651239 ! embryonic gut development GO:0048566 19 11 0,000 0,04070242 0,06646792 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04070242 0,06642352 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04070242 0,06637918 ! activation of innate immune response GO:0002218 16 11 0,000 0,04070242 0,0663349 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04070242 0,06629068 ! lysogeny GO:0030069 22 11 0,000 0,04070242 0,06624651 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04070242 0,06620241 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04070242 0,06615836 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04070242 0,06611437 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,04109826 0,06671298 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,04197517 0,0680912 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,0428591 0,06947895 GO:0070201|regulation of establishment of protein localization, ! amine biosynthetic process GO:0009309 146 88 1,000 0,04374998 0,07087612 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04432007 0,07175211 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04432007 0,07170459 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,04432007 0,07165713 ! mating GO:0007618 17 12 0,000 0,04432007 0,07160974 ! protein complex disassembly GO:0043241 28 12 0,000 0,04432007 0,07156241 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04432007 0,07151514 ! hippocampus development GO:0021766 29 12 0,000 0,04432007 0,07146794 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,04432007 0,0714208 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04432007 0,07137372 ! T cell proliferation GO:0042098 32 12 0,000 0,04432007 0,0713267 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04432007 0,07127974 ! ventral spinal cord development GO:0021517 25 12 0,000 0,04432007 0,07123285 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04432007 0,07118602 ! drug transport GO:0015893 16 12 0,000 0,04432007 0,07113924 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04432007 0,07109253 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,04432007 0,07104589 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04432007 0,0709993 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04432007 0,07095277 ! mitotic spindle organization GO:0007052 23 12 0,000 0,04432007 0,07090631 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04432007 0,0708599 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04432007 0,07081356 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04432007 0,07076727 ! lipid digestion GO:0044241 21 12 0,000 0,04432007 0,07072105 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04432007 0,07067489 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04432007 0,07062879 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04432007 0,07058274 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04432007 0,07053676 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04432007 0,07049084 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04432007 0,07044498 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,04432007 0,07039917 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,04432007 0,07035343 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04432007 0,07030775 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04432007 0,07026212 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04432007 0,07021656 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04432007 0,07017105 ! cranial nerve development GO:0021545 23 12 0,000 0,04432007 0,0701256 ! fucose catabolic process GO:0019317 25 12 0,000 0,04432007 0,07008021 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04432007 0,07003488 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04432007 0,06998961 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04432007 0,0699444 ! zymogen activation GO:0031638 18 12 0,000 0,04432007 0,06989924 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04432007 0,06985415 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04432007 0,06980911 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,04432007 0,06976413 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04432007 0,06971921 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04432007 0,06967434 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,04432007 0,06962954 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,04432007 0,06958479 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04432007 0,0695401 ! defense response to fungus GO:0050832 15 12 0,000 0,04432007 0,06949546 ! developmental induction GO:0031128 22 12 0,000 0,04432007 0,06945088 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,04432007 0,06940636 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04432007 0,0693619 ! response to cold GO:0009409 17 12 0,000 0,04432007 0,0693175 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04432007 0,06927315 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04432007 0,06922885 ! localization within membrane GO:0051668 26 12 0,000 0,04432007 0,06918462 ! regulation of DNA binding GO:0051101 167 89 1,000 0,04464774 0,06965161 ! regulation of neurological system process GO:0031644 175 89 1,000 0,04464774 0,06960717 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,04792418 0,07466758 ! cGMP metabolic process GO:0046068 18 13 0,000 0,04792418 0,07461999 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,04792418 0,07457246 ! regulation of chemokine production GO:0032642 18 13 0,000 0,04792418 0,07452499 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,04792418 0,07447758 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,04792418 0,07443024 ! peroxisomal transport GO:0043574 28 13 0,000 0,04792418 0,07438295 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,04792418 0,07433572 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,04792418 0,07428855 ! organelle fusion GO:0048284 36 13 0,000 0,04792418 0,07424145 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,04792418 0,0741944 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,04792418 0,07414741 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,04792418 0,07410048 ! endocrine pancreas development GO:0031018 25 13 0,000 0,04792418 0,07405361 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,04792418 0,0740068 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,04792418 0,07396005 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,04792418 0,07391336 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,04792418 0,07386673 ! methionine metabolic process GO:0006555 31 13 0,000 0,04792418 0,07382015 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,04792418 0,07377364 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,04792418 0,07372718 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,04792418 0,07368078 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,04792418 0,07363444 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,04792418 0,07358816 ! asymmetric protein localization GO:0008105 24 13 0,000 0,04792418 0,07354194 ! monoamine transport GO:0015844 21 13 0,000 0,04792418 0,07349577 ! L-glutamate transport GO:0015813 30 13 0,000 0,04792418 0,07344966 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,04792418 0,07340361 ! protein homotetramerization GO:0051289 24 13 0,000 0,04792418 0,07335762 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,04792418 0,07331169 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,04792418 0,07326581 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,04792418 0,07321999 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,04792418 0,07317423 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,04792418 0,07312852 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,04792418 0,07308287 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,04792418 0,07303728 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,04792418 0,07299175 ! histone methylation GO:0016571 29 13 0,000 0,04792418 0,07294627 ! chromatin silencing GO:0006342 29 13 0,000 0,04792418 0,07290085 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,04792418 0,07285548 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,04792418 0,07281017 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,04792418 0,07276492 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,04792418 0,07271973 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,04792418 0,07267459 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,04792418 0,0726295 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,04792418 0,07258448 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,04792418 0,07253951 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,04792418 0,07249459 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,04792418 0,07244973 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,04792418 0,07240492 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,04792418 0,07236017 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,04792418 0,07231548 ! insulin secretion GO:0030073 24 13 0,000 0,04792418 0,07227084 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,04792418 0,07222626 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,04792418 0,07218173 ! acrosome reaction GO:0007340 19 13 0,000 0,04792418 0,07213725 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,04792418 0,07209283 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,04792418 0,07204847 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,04830637 0,0725784 ! female pregnancy GO:0007565 166 94 1,000 0,04923762 0,07393208 ! regulation of membrane potential GO:0042391 179 94 1,000 0,04923762 0,07388667 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,05017536 0,07524765 ! sex differentiation GO:0007548 171 96 1,000 0,05111956 0,07661662 ! response to protein stimulus GO:0051789 158 96 1,000 0,05111956 0,07656964 ! rRNA transcription GO:0009303 28 14 0,000 0,05151479 0,07711436 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05151479 0,07706714 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05151479 0,07701997 ! water transport GO:0006833 21 14 0,000 0,05151479 0,07697287 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05151479 0,07692582 ! non-recombinational repair GO:0000726 29 14 0,000 0,05151479 0,07687882 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05151479 0,07683189 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05151479 0,07678501 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05151479 0,07673819 ! lipid localization GO:0010876 32 14 0,000 0,05151479 0,07669143 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05151479 0,07664472 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05151479 0,07659807 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05151479 0,07655148 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05151479 0,07650495 ! arginine metabolic process GO:0006525 21 14 0,000 0,05151479 0,07645847 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05151479 0,07641204 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05151479 0,07636568 ! regulation of heart rate GO:0002027 25 14 0,000 0,05151479 0,07631937 ! organic alcohol transport GO:0015850 29 14 0,000 0,05151479 0,07627311 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,05151479 0,07622691 ! embryo implantation GO:0007566 30 14 0,000 0,05151479 0,07618077 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05151479 0,07613469 ! bone mineralization GO:0030282 18 14 0,000 0,05151479 0,07608865 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05151479 0,07604268 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05151479 0,07599676 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05151479 0,0759509 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05151479 0,07590509 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05151479 0,07585933 ! ribosome assembly GO:0042255 18 14 0,000 0,05151479 0,07581364 ! cerebellum development GO:0021549 23 14 0,000 0,05151479 0,07576799 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05151479 0,0757224 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05151479 0,07567687 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05151479 0,07563139 ! NADP metabolic process GO:0006739 24 14 0,000 0,05151479 0,07558597 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05151479 0,0755406 ! oxygen transport GO:0015671 22 14 0,000 0,05151479 0,07549528 ! male genitalia development GO:0030539 26 14 0,000 0,05151479 0,07545002 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05151479 0,07540481 ! regulation of axon extension GO:0030516 43 14 0,000 0,05151479 0,07535966 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05151479 0,07531456 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05151479 0,07526952 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,05207014 0,07603548 ! transcription initiation GO:0006352 171 97 1,000 0,05207014 0,07599006 ! lactation GO:0007595 30 15 0,000 0,05509197 0,08035204 ! reproductive cellular process GO:0048610 22 15 0,000 0,05509197 0,0803041 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05509197 0,08025622 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05509197 0,08020839 ! superoxide anion generation GO:0042554 22 15 0,000 0,05509197 0,08016062 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05509197 0,0801129 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05509197 0,08006524 ! copper ion transport GO:0006825 22 15 0,000 0,05509197 0,08001764 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05509197 0,0799701 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,05509197 0,07992261 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05509197 0,07987518 ! sulfate transport GO:0008272 27 15 0,000 0,05509197 0,0798278 ! response to cAMP GO:0051591 25 15 0,000 0,05509197 0,07978048 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05509197 0,07973322 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,05509197 0,07968601 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,05509197 0,07963886 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05509197 0,07959176 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05509197 0,07954472 ! vesicle coating GO:0006901 38 15 0,000 0,05509197 0,07949774 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05509197 0,07945081 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05509197 0,07940394 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05509197 0,07935712 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05509197 0,07931036 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05509197 0,07926365 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05509197 0,07921699 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05509197 0,0791704 ! histone deacetylation GO:0016575 24 15 0,000 0,05509197 0,07912385 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05509197 0,07907736 ! water homeostasis GO:0030104 28 15 0,000 0,05509197 0,07903093 ! cofactor transport GO:0051181 30 15 0,000 0,05509197 0,07898455 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05509197 0,07893822 ! muscle maintenance GO:0046716 26 15 0,000 0,05509197 0,07889195 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05509197 0,07884574 ! intestinal absorption GO:0050892 31 15 0,000 0,05509197 0,07879957 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05509197 0,07875347 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05509197 0,07870741 ! cell killing GO:0001906 32 15 0,000 0,05509197 0,07866141 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05509197 0,07861546 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05509197 0,07856957 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05509197 0,07852373 ! actin filament polymerization GO:0030041 27 15 0,000 0,05509197 0,07847794 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05509197 0,07843221 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,05865575 0,08345719 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,05865575 0,08340861 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,05865575 0,08336009 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,05865575 0,08331163 ! bone remodeling GO:0046849 28 16 0,000 0,05865575 0,08326322 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,05865575 0,08321486 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,05865575 0,08316657 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05865575 0,08311833 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,05865575 0,08307014 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,05865575 0,08302201 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,05865575 0,08297394 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,05865575 0,08292592 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,05865575 0,08287796 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,05865575 0,08283006 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,05865575 0,0827822 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,05865575 0,08273441 ! protein polyubiquitination GO:0000209 41 16 0,000 0,05865575 0,08268667 ! glutamate metabolic process GO:0006536 25 16 0,000 0,05865575 0,08263898 ! pituitary gland development GO:0021983 30 16 0,000 0,05865575 0,08259135 ! response to osmotic stress GO:0006970 27 16 0,000 0,05865575 0,08254378 ! lysosomal transport GO:0007041 31 16 0,000 0,05865575 0,08249626 ! fructose metabolic process GO:0006000 25 16 0,000 0,05865575 0,08244879 ! L-amino acid transport GO:0015807 33 16 0,000 0,05865575 0,08240138 ! stem cell development GO:0048864 46 16 0,000 0,05865575 0,08235402 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,05865575 0,08230672 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 36 16 0,000 0,05865575 0,08225947 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,05865575 0,08221228 ! axon cargo transport GO:0008088 46 16 0,000 0,05865575 0,08216514 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,05865575 0,08211805 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,05865575 0,08207102 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,05865575 0,08202404 ! neuron recognition GO:0008038 40 16 0,000 0,05865575 0,08197711 ! mRNA splice site selection GO:0006376 44 16 0,000 0,05865575 0,08193024 ! tissue regeneration GO:0042246 27 16 0,000 0,05865575 0,08188343 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,05865575 0,08183666 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,05865575 0,08178995 ! biomineral formation GO:0031214 22 16 0,000 0,05865575 0,0817433 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,05865575 0,08169669 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,05865575 0,08165014 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,05865575 0,08160364 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,05865575 0,0815572 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,05865575 0,08151081 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,05865575 0,08146447 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,05865575 0,08141818 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,05865575 0,08137195 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! peptide hormone processing GO:0016486 27 16 0,000 0,05865575 0,08132576 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06220619 0,08619951 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,06220619 0,08615064 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,06220619 0,08610183 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,06220619 0,08605307 ! signal complex assembly GO:0007172 47 17 0,000 0,06220619 0,08600437 ! endothelial cell migration GO:0043542 31 17 0,000 0,06220619 0,08595573 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06220619 0,08590714 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06220619 0,0858586 ! glial cell development GO:0021782 28 17 0,000 0,06220619 0,08581012 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06220619 0,0857617 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06220619 0,08571333 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,06220619 0,08566501 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06220619 0,08561675 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06220619 0,08556854 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,06220619 0,08552039 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,06220619 0,08547229 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,06220619 0,08542424 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,06220619 0,08537625 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06220619 0,08532831 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06220619 0,08528043 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,06220619 0,0852326 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,06220619 0,08518483 ! membrane budding GO:0006900 42 17 0,000 0,06220619 0,0851371 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06220619 0,08508943 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06220619 0,08504182 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06220619 0,08499426 ! genitalia development GO:0048806 32 17 0,000 0,06220619 0,08494675 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06220619 0,08489929 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06220619 0,08485189 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06220619 0,08480454 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06220619 0,08475724 ! steroid catabolic process GO:0006706 34 17 0,000 0,06220619 0,08470999 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06220619 0,0846628 ! gas transport GO:0015669 26 17 0,000 0,06220619 0,08461566 ! organic cation transport GO:0015695 32 17 0,000 0,06220619 0,08456857 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06220619 0,08452154 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06220619 0,08447456 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,06574334 0,08922833 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,06574334 0,08917878 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,06574334 0,08912929 ! limbic system development GO:0021761 40 18 0,000 0,06574334 0,08907986 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,06574334 0,08903048 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,06574334 0,08898116 ! adult walking behavior GO:0007628 36 18 0,000 0,06574334 0,08893189 ! patterning of blood vessels GO:0001569 43 18 0,000 0,06574334 0,08888267 ! heart looping GO:0001947 34 18 0,000 0,06574334 0,08883351 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,06574334 0,08878441 ! centrosome cycle GO:0007098 26 18 0,000 0,06574334 0,08873535 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,06574334 0,08868635 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,06574334 0,08863741 ! glycine metabolic process GO:0006544 30 18 0,000 0,06574334 0,08858852 ! glutamine metabolic process GO:0006541 29 18 0,000 0,06574334 0,08853969 ! response to retinoic acid GO:0032526 31 18 0,000 0,06574334 0,0884909 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,06574334 0,08844217 ! DNA integration GO:0015074 32 18 0,000 0,06574334 0,0883935 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,06574334 0,08834488 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,06574334 0,08829631 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,06574334 0,0882478 ! neural crest cell migration GO:0001755 41 18 0,000 0,06574334 0,08819933 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,06574334 0,08815093 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,06574334 0,08810257 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,06574334 0,08805427 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,06574334 0,08800602 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,06574334 0,08795783 ! detection of bacterium GO:0016045 22 18 0,000 0,06574334 0,08790968 ! nerve development GO:0021675 34 18 0,000 0,06574334 0,08786159 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,06574334 0,08781355 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,06574334 0,08776557 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,06926725 0,09241939 ! positive regulation of translation GO:0045727 31 19 0,000 0,06926725 0,09236894 ! negative regulation of defense response GO:0031348 27 19 0,000 0,06926725 0,09231855 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,06926725 0,09226821 ! neuron maturation GO:0042551 46 19 0,000 0,06926725 0,09221793 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,06926725 0,0921677 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,06926725 0,09211753 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,06926725 0,09206741 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,06926725 0,09201735 ! inositol metabolic process GO:0006020 33 19 0,000 0,06926725 0,09196734 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,06926725 0,09191738 ! memory GO:0007613 34 19 0,000 0,06926725 0,09186748 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,06926725 0,09181763 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,06926725 0,09176784 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,06926725 0,0917181 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,06926725 0,09166842 ! cerebral cortex development GO:0021987 40 19 0,000 0,06926725 0,09161879 ! response to vitamin A GO:0033189 32 19 0,000 0,06926725 0,09156921 ! heme metabolic process GO:0042168 40 19 0,000 0,06926725 0,09151969 ! neuromuscular junction development GO:0007528 43 19 0,000 0,06926725 0,09147022 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,06926725 0,0914208 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,06926725 0,09137144 ! response to fungus GO:0009620 26 19 0,000 0,06926725 0,09132213 ! peptide cross-linking GO:0018149 39 19 0,000 0,06926725 0,09127287 ! protein export from nucleus GO:0006611 40 19 0,000 0,06926725 0,09122366 ! heart process GO:0003015 32 19 0,000 0,06926725 0,09117451 GO:0060047|heart contraction, ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,06926725 0,09112542 ! visual learning GO:0008542 38 19 0,000 0,06926725 0,09107637 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,06926725 0,09102738 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,06926725 0,09097844 ! vitamin transport GO:0051180 31 19 0,000 0,06926725 0,09092955 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,06926725 0,09088072 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,06926725 0,09083194 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,06926725 0,09078321 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,06926725 0,09073453 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,06926725 0,0906859 ! cilium assembly GO:0042384 38 19 0,000 0,06926725 0,09063733 ! peptide hormone secretion GO:0030072 32 19 0,000 0,06926725 0,09058881 ! protein secretion GO:0009306 45 20 0,000 0,07277797 0,09512926 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,07277797 0,09507838 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,07277797 0,09502757 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,07277797 0,0949768 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,07277797 0,0949261 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,07277797 0,09487544 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,07277797 0,09482484 ! response to vitamin GO:0033273 36 20 0,000 0,07277797 0,0947743 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,07277797 0,0947238 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,07277797 0,09467336 ! bile acid metabolic process GO:0008206 34 20 0,000 0,07277797 0,09462298 ! retinoid metabolic process GO:0001523 34 20 0,000 0,07277797 0,09457265 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,07277797 0,09452237 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,07277797 0,09447215 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,07277797 0,09442197 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,07277797 0,09437186 ! body fluid secretion GO:0007589 33 20 0,000 0,07277797 0,09432179 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,07277797 0,09427178 ! peptide secretion GO:0002790 38 20 0,000 0,07277797 0,09422182 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,07277797 0,09417192 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,07277797 0,09412206 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,07277797 0,09407226 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,07277797 0,09402252 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,07277797 0,09397282 ! cell-cell junction organization GO:0045216 43 20 0,000 0,07277797 0,09392318 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,07277797 0,09387359 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,07277797 0,09382405 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,07277797 0,09377457 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,07277797 0,09372513 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,07277797 0,09367575 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,07277797 0,09362642 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,07277797 0,09357715 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,07277797 0,09352792 ! negative regulation of translation GO:0017148 32 20 0,000 0,07277797 0,09347875 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,07277797 0,09342963 ! regulation of cell killing GO:0031341 46 21 0,000 0,07627554 0,09786825 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,07627554 0,09781687 ! hormone secretion GO:0046879 39 21 0,000 0,07627554 0,09776555 ! cAMP metabolic process GO:0046058 41 21 0,000 0,07627554 0,09771429 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,07627554 0,09766307 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,07627554 0,09761192 ! smooth muscle contraction GO:0006939 48 21 0,000 0,07627554 0,09756081 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,07627554 0,09750976 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,07627554 0,09745876 ! plasma membrane fusion GO:0045026 33 21 0,000 0,07627554 0,09740781 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,07627554 0,09735692 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,07627554 0,09730608 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,07627554 0,0972553 ! sensory perception of pain GO:0019233 33 21 0,000 0,07627554 0,09720456 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,07627554 0,09715388 ! diencephalon development GO:0021536 36 21 0,000 0,07627554 0,09710326 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,07627554 0,09705268 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,07627554 0,09700216 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,07627554 0,09695169 ! collagen catabolic process GO:0030574 29 21 0,000 0,07627554 0,09690127 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,07627554 0,09685091 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,07627554 0,0968006 ! sperm-egg recognition GO:0035036 23 21 0,000 0,07627554 0,09675034 ! actin filament-based movement GO:0030048 47 21 0,000 0,07627554 0,09670013 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,07976002 0,10106521 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,07976002 0,10101282 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,07976002 0,10096048 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,07976002 0,10090819 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,07976002 0,10085596 ! microtubule-based transport GO:0010970 59 22 0,000 0,07976002 0,10080379 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,07976002 0,10075167 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,07976002 0,1006996 ! vacuolar transport GO:0007034 41 22 0,000 0,07976002 0,10064758 ! central nervous system neuron development GO:0021954 47 22 0,000 0,07976002 0,10059562 ! fucose metabolic process GO:0006004 44 22 0,000 0,07976002 0,10054372 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,07976002 0,10049186 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,07976002 0,10044006 ! stem cell differentiation GO:0048863 57 22 0,000 0,07976002 0,10038832 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,07976002 0,10033662 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,07976002 0,10028498 ! cytolysis GO:0019835 27 22 0,000 0,07976002 0,1002334 ! vasodilation GO:0042311 40 22 0,000 0,07976002 0,10018186 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,07976002 0,10013038 ! G1 phase GO:0051318 44 22 0,000 0,07976002 0,10007895 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,07976002 0,10002758 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,07976002 0,09997626 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,07976002 0,09992499 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,07976002 0,09987377 ! sarcomere organization GO:0045214 32 22 0,000 0,07976002 0,0998226 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,07976002 0,09977149 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,07976002 0,09972043 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,07976002 0,09966942 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,07976002 0,09961847 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,07976002 0,09956756 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,07976002 0,09951671 ! protein stabilization GO:0050821 41 22 0,000 0,07976002 0,09946591 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,08323145 0,10374206 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,08323145 0,10368915 ! gluconeogenesis GO:0006094 38 23 0,000 0,08323145 0,1036363 ! glycerol metabolic process GO:0006071 40 23 0,000 0,08323145 0,10358351 ! viral genome replication GO:0019079 44 23 0,000 0,08323145 0,10353077 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,08323145 0,10347808 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,08323145 0,10342545 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,08323145 0,10337287 ! axis specification GO:0009798 43 23 0,000 0,08323145 0,10332034 ! visual behavior GO:0007632 46 23 0,000 0,08323145 0,10326787 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,08323145 0,10321545 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,08323145 0,10316308 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,08323145 0,10311077 ! peroxisome organization GO:0007031 43 23 0,000 0,08323145 0,1030585 ! lysosome organization GO:0007040 47 23 0,000 0,08323145 0,1030063 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,08323145 0,10295414 ! vesicle targeting GO:0006903 49 23 0,000 0,08323145 0,10290204 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,08323145 0,10284999 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,08323145 0,10279799 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,08323145 0,10274605 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,08323145 0,10269416 ! DNA modification GO:0006304 36 23 0,000 0,08323145 0,10264232 ! fatty acid transport GO:0015908 47 23 0,000 0,08323145 0,10259053 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,08323145 0,10253879 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,08323145 0,10248711 ! hormone transport GO:0009914 41 23 0,000 0,08323145 0,10243548 ! cell-cell recognition GO:0009988 28 23 0,000 0,08323145 0,1023839 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,08323145 0,10233237 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,08323145 0,1022809 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,08323145 0,10222948 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,08668988 0,10642381 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,08668988 0,10637036 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,08668988 0,10631696 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,08668988 0,10626361 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,08668988 0,10621032 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,08668988 0,10615708 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 0,000 0,08668988 0,1061039 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,08668988 0,10605077 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,08668988 0,10599769 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,08668988 0,10594466 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,08668988 0,10589169 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,08668988 0,10583877 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,08668988 0,1057859 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,08668988 0,10573309 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,08668988 0,10568033 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,08668988 0,10562762 ! membrane depolarization GO:0051899 45 24 0,000 0,08668988 0,10557496 ! pallium development GO:0021543 56 24 0,000 0,08668988 0,10552236 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,08668988 0,10546981 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,08668988 0,10541731 ! regulation of oxidoreductase activity GO:0051341 48 24 0,000 0,08668988 0,10536487 ! platelet activation GO:0030168 41 24 0,000 0,08668988 0,10531247 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,08668988 0,10526013 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,08668988 0,10520784 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,08668988 0,1051556 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,08668988 0,10510341 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,08668988 0,10505128 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,08668988 0,1049992 ! regulation of amine transport GO:0051952 41 24 0,000 0,08668988 0,10494717 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,08668988 0,10489519 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,09013536 0,10901024 ! leukocyte adhesion GO:0007159 55 25 0,000 0,09013536 0,10895631 ! phototransduction GO:0007602 37 25 0,000 0,09013536 0,10890242 ! keratinization GO:0031424 37 25 0,000 0,09013536 0,10884859 ! vasculogenesis GO:0001570 49 25 0,000 0,09013536 0,10879481 ! vacuole organization GO:0007033 49 25 0,000 0,09013536 0,10874108 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,09013536 0,10868741 ! receptor metabolic process GO:0043112 53 25 0,000 0,09013536 0,10863379 ! chromosome condensation GO:0030261 48 25 0,000 0,09013536 0,10858022 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,09013536 0,10852671 ! immunoglobulin production GO:0002377 62 25 0,000 0,09013536 0,10847325 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,09013536 0,10841984 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,09013536 0,10836648 ! liver development GO:0001889 55 25 0,000 0,09013536 0,10831318 ! myelination GO:0042552 50 26 0,000 0,09356795 0,11238274 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,09356795 0,11232751 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,09356795 0,11227234 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,09356795 0,11221723 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,09356795 0,11216216 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,09356795 0,11210716 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,09356795 0,1120522 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,09356795 0,1119973 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,09356795 0,11194245 ! digestive system process GO:0022600 49 26 0,000 0,09356795 0,11188766 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,09356795 0,11183292 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,09356795 0,11177824 ! neural crest cell development GO:0014032 59 26 0,000 0,09356795 0,1117236 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,09356795 0,11166902 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,09356795 0,1116145 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,09356795 0,11156002 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,09356795 0,11150561 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,09356795 0,11145124 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,09356795 0,11139693 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,09356795 0,11134266 GO:0045840|positive regulation of mitosis, ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,09356795 0,11128846 ! blastocyst development GO:0001824 50 26 0,000 0,09356795 0,1112343 ! telomere organization GO:0032200 46 26 0,000 0,09356795 0,1111802 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,09356795 0,11112615 ! neural tube closure GO:0001843 58 26 0,000 0,09356795 0,11107215 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,09356795 0,11101821 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,09356795 0,11096432 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,09356795 0,11091048 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,09698767 0,11490829 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,09698767 0,11485259 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,09698767 0,11479694 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,09698767 0,11474135 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,09698767 0,11468581 ! iron ion transport GO:0006826 65 27 0,000 0,09698767 0,11463033 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,09698767 0,1145749 ! superoxide metabolic process GO:0006801 41 27 0,000 0,09698767 0,11451952 ! tube lumen formation GO:0035148 59 27 0,000 0,09698767 0,1144642 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,09698767 0,11440893 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,09698767 0,11435371 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,09698767 0,11429855 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,09698767 0,11424344 ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,09698767 0,11418838 ! neuron fate commitment GO:0048663 52 28 0,000 0,1003946 0,11814258 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,1003946 0,1180857 ! vesicle docking GO:0048278 55 28 0,000 0,1003946 0,11802887 ! circadian rhythm GO:0007623 56 28 0,000 0,1003946 0,1179721 ! dendrite development GO:0016358 67 28 0,000 0,1003946 0,11791538 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,1003946 0,11785872 ! sperm motility GO:0030317 37 28 0,000 0,1003946 0,11780211 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,1003946 0,11774556 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,1003946 0,11768906 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,1003946 0,11763261 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,1003946 0,11757622 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,1003946 0,11751988 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,1003946 0,1174636 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,1003946 0,11740737 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,1003946 0,11735119 ! lipid oxidation GO:0034440 48 28 0,000 0,1003946 0,11729507 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,1003946 0,117239 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,1003946 0,11718299 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,10378876 0,12108689 ! translational initiation GO:0006413 66 29 0,000 0,10378876 0,12102909 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,10378876 0,12097135 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,10378876 0,12091366 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,10378876 0,12085602 ! primary neural tube formation GO:0014020 61 29 0,000 0,10378876 0,12079845 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,10378876 0,12074092 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,10378876 0,12068346 ! synaptogenesis GO:0007416 46 29 0,000 0,10378876 0,12062604 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,10378876 0,12056868 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,10378876 0,12051138 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,10378876 0,12045413 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,10717021 0,12431948 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,10717021 0,12426048 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,10717021 0,12420153 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,10717021 0,12414264 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,10717021 0,12408381 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,10717021 0,12402503 ! acute-phase response GO:0006953 50 30 0,000 0,10717021 0,1239663 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,10717021 0,12390763 ! myofibril assembly GO:0030239 50 30 0,000 0,10717021 0,12384902 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,10717021 0,12379046 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,10717021 0,12373196 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,10717021 0,12367351 ! cell fate determination GO:0001709 64 30 0,000 0,10717021 0,12361512 ! phospholipid transport GO:0015914 65 30 0,000 0,10717021 0,12355679 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,10717021 0,1234985 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,10717021 0,12344028 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,10717021 0,12338211 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,10717021 0,12332399 GO:0043433|negative regulation of transcription factor activity, ! regulation of coagulation GO:0050818 52 30 0,000 0,10717021 0,12326593 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,110539 0,12708084 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,110539 0,12702106 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,110539 0,12696135 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,110539 0,12690168 ! regulation of innate immune response GO:0045088 57 31 0,000 0,110539 0,12684208 ! peptide transport GO:0015833 60 31 0,000 0,110539 0,12678253 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,110539 0,12672303 ! detection of light stimulus GO:0009583 44 31 0,000 0,110539 0,12666359 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,110539 0,12660421 ! natural killer cell activation GO:0030101 50 31 0,000 0,110539 0,12654488 ! ensheathment of neurons GO:0007272 64 31 0,000 0,110539 0,12648561 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,110539 0,1264264 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,110539 0,12636724 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,110539 0,12630813 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,110539 0,12624908 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,11389518 0,13002145 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,11389518 0,12996073 ! spindle organization GO:0007051 50 32 0,000 0,11389518 0,12990005 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,11389518 0,12983944 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,11389518 0,12977888 ! muscle cell development GO:0055001 52 32 0,000 0,11389518 0,12971837 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,11389518 0,12965793 ! peripheral nervous system development GO:0007422 68 32 0,000 0,11389518 0,12959754 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,11389518 0,1295372 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,11389518 0,12947693 ! gene silencing GO:0016458 71 32 0,000 0,11389518 0,1294167 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,11723878 0,13315404 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,11723878 0,13309216 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,11723878 0,13303035 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,11723878 0,13296859 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,11723878 0,13290688 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,11723878 0,13284524 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,11723878 0,13278365 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,11723878 0,13272212 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,11723878 0,13266065 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,11723878 0,13259923 ! glial cell differentiation GO:0010001 67 34 0,000 0,12056986 0,13630364 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,12056986 0,13624059 ! cholesterol transport GO:0030301 62 34 0,000 0,12056986 0,13617761 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,12056986 0,13611468 ! spliceosome assembly GO:0000245 75 34 0,000 0,12056986 0,13605181 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,12056986 0,135989 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,12056986 0,13592624 ! cell fate specification GO:0001708 56 34 0,000 0,12056986 0,13586355 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,12056986 0,13580091 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,12388846 0,13947443 ! negative regulation of secretion GO:0051048 68 35 0,000 0,12388846 0,13941019 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,12388846 0,139346 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,12388846 0,13928188 ! membrane docking GO:0022406 69 35 0,000 0,12388846 0,13921781 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,12388846 0,1391538 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,12388846 0,13908985 ! ceramide metabolic process GO:0006672 72 35 0,000 0,12388846 0,13902596 ! telencephalon development GO:0021537 81 35 0,000 0,12388846 0,13896213 ! sterol transport GO:0015918 63 35 0,000 0,12388846 0,13889836 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,12388846 0,13883464 ! placenta development GO:0001890 53 35 0,000 0,12388846 0,13877098 ! vesicle localization GO:0051648 70 35 0,000 0,12388846 0,13870739 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,12719464 0,14234379 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,12719464 0,14227862 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,12719464 0,1422135 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,12719464 0,14214844 ! protein targeting to membrane GO:0006612 75 36 0,000 0,12719464 0,14208345 ! regulation of proteolysis GO:0030162 77 36 0,000 0,12719464 0,14201851 ! aerobic respiration GO:0009060 56 36 0,000 0,12719464 0,14195363 ! cytokine production GO:0001816 68 36 0,000 0,12719464 0,14188881 ! embryonic organ development GO:0048568 67 36 0,000 0,12719464 0,14182405 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,12719464 0,14175935 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,12719464 0,14169471 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,13048843 0,14529774 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,13048843 0,14523154 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,13048843 0,14516541 ! sister chromatid segregation GO:0000819 65 37 0,000 0,13048843 0,14509933 ! actomyosin structure organization GO:0031032 68 37 0,000 0,13048843 0,14503332 ! tissue remodeling GO:0048771 78 37 0,000 0,13048843 0,14496736 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,13048843 0,14490147 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,13048843 0,14483563 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,13048843 0,14476986 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,13048843 0,14470414 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,13376988 0,14827578 ! meiosis I GO:0007127 74 38 0,000 0,13376988 0,14820854 ! organic anion transport GO:0015711 82 38 0,000 0,13376988 0,14814135 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,13376988 0,14807423 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,13376988 0,14800717 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,13376988 0,14794016 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,13376988 0,14787322 ! spermatid development GO:0007286 69 38 0,000 0,13376988 0,14780634 ! neural tube formation GO:0001841 79 38 0,000 0,13376988 0,14773952 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,13703904 0,15128169 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,13703904 0,15121336 ! negative regulation of binding GO:0051100 71 39 0,000 0,13703904 0,15114509 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,13703904 0,15107689 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,13703904 0,15100874 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,13703904 0,15094066 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,13703904 0,15087264 ! mammary gland development GO:0030879 93 40 0,000 0,14029596 0,15438875 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,14029596 0,15431924 ! learning GO:0007612 82 40 0,000 0,14029596 0,15424979 ! lipid homeostasis GO:0055088 75 40 0,000 0,14029596 0,1541804 ! mismatch repair GO:0006298 58 40 0,000 0,14029596 0,15411107 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,14029596 0,15404181 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,14029596 0,15397261 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,14029596 0,15390347 ! RNA export from nucleus GO:0006405 61 41 0,000 0,14354067 0,15739222 ! mRNA catabolic process GO:0006402 79 41 0,000 0,14354067 0,15732161 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,14354067 0,15725106 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,14354067 0,15718057 ! feeding behavior GO:0007631 69 41 0,000 0,14354067 0,15711015 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,14354067 0,15703979 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,14354067 0,1569695 ! spermatid differentiation GO:0048515 73 41 0,000 0,14354067 0,15689927 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,14354067 0,1568291 ! RNA modification GO:0009451 64 41 0,000 0,14354067 0,15675899 ! organic ether metabolic process GO:0018904 59 42 0,000 0,14677323 0,16021761 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,14677323 0,16014605 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,14677323 0,16007456 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,14677323 0,16000313 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,14677323 0,15993176 ! regulation of protein secretion GO:0050708 77 42 0,000 0,14677323 0,15986046 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,14677323 0,15978922 ! cytokinesis GO:0000910 84 42 0,000 0,14677323 0,15971804 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,14677323 0,15964693 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,14999368 0,16307724 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,14999368 0,1630047 ! regulation of tube size GO:0035150 76 43 0,000 0,14999368 0,16293222 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,14999368 0,16285981 ! glucose transport GO:0015758 66 43 0,000 0,14999368 0,16278746 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,14999368 0,16271517 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,14999368 0,16264295 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,14999368 0,16257079 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,14999368 0,1624987 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,14999368 0,16242667 ! ion transmembrane transport GO:0034220 79 43 0,000 0,14999368 0,1623547 ! neuron migration GO:0001764 85 43 0,000 0,14999368 0,1622828 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,14999368 0,16221096 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,15320206 0,16560736 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,15320206 0,16553412 ! hexose transport GO:0008645 68 44 0,000 0,15320206 0,16546094 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,15320206 0,16538782 ! phagocytosis GO:0006909 105 44 0,000 0,15320206 0,16531477 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,15320206 0,16524179 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,15639843 0,1686149 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,15639843 0,16854052 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,15639843 0,16846621 ! biopolymer methylation GO:0043414 91 45 0,000 0,15639843 0,16839196 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,15639843 0,16831778 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,15639843 0,16824366 ! polyol metabolic process GO:0019751 77 45 0,000 0,15639843 0,16816961 ! maintenance of location in cell GO:0051651 101 45 0,000 0,15639843 0,16809563 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,15958282 0,17144275 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,15958282 0,17136739 ! glycolysis GO:0006096 71 46 0,000 0,15958282 0,1712921 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,15958282 0,17121687 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,15958282 0,17114171 ! neural tube development GO:0021915 91 47 0,000 0,16275528 0,17446737 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,16275528 0,17439085 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,16591585 0,17769944 ! endosome transport GO:0016197 127 48 0,000 0,16591585 0,17762157 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,16591585 0,17754376 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,16591585 0,17746603 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,16591585 0,17738836 ! methylation GO:0032259 97 48 0,000 0,16591585 0,17731077 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,16906457 0,18059675 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,16906457 0,18051781 ! JNK cascade GO:0007254 106 49 0,000 0,16906457 0,18043895 ! protein homooligomerization GO:0051260 84 49 0,000 0,16906457 0,18036016 ! regulation of action potential GO:0001508 102 50 0,000 0,17220151 0,18362649 ! regulation of ion transport GO:0043269 86 50 0,000 0,17220151 0,18354637 ! endocrine system development GO:0035270 109 50 0,000 0,17220151 0,18346632 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,17220151 0,18338635 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,17220151 0,18330644 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,17220151 0,1832266 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,17220151 0,18314683 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,17532668 0,18638951 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,17844015 0,18961691 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,17844015 0,18953447 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,17844015 0,1894521 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,17844015 0,1893698 ! excretion GO:0007588 87 52 0,000 0,17844015 0,18928757 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,17844015 0,18920542 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,17844015 0,18912333 ! amino acid activation GO:0043038 98 52 0,000 0,17844015 0,18904132 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,18154194 0,19224403 ! inner ear development GO:0048839 89 53 0,000 0,18154194 0,19216073 ! chromatin remodeling GO:0006338 122 53 0,000 0,18154194 0,19207751 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,18154194 0,19199436 ! synapse organization GO:0050808 102 53 0,000 0,18154194 0,19191128 ! regulation of angiogenesis GO:0045765 125 54 0,000 0,18463212 0,19509354 ! regulation of translational initiation GO:0006446 87 54 0,000 0,18463212 0,19500919 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,18463212 0,19492492 ! activation of phospholipase C activity GO:0007202 110 54 0,000 0,18463212 0,19484072 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 0,000 0,18463212 0,19475659 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,18463212 0,19467254 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,18463212 0,19458855 ! regulation of cell shape GO:0008360 142 54 0,000 0,18463212 0,19450464 ! RNA catabolic process GO:0006401 103 55 0,000 0,18771071 0,19766262 ! positive regulation of phospholipase activity GO:0010518 111 55 0,000 0,18771071 0,19757745 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,18771071 0,19749237 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,18771071 0,19740735 ! cell recognition GO:0008037 98 55 0,000 0,18771071 0,19732241 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,18771071 0,19723754 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,19077777 0,20037407 ! glucose catabolic process GO:0006007 88 56 0,000 0,19077777 0,20028796 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,19077777 0,20020193 ! RNA elongation GO:0006354 90 56 0,000 0,19077777 0,20011597 ! chloride transport GO:0006821 102 57 0,000 0,19383333 0,20323383 ! regulation of phospholipase activity GO:0010517 113 57 0,000 0,19383333 0,20314664 ! regulation of actin filament length GO:0030832 118 58 0,000 0,19687744 0,20624854 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,19687744 0,20616013 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,19687744 0,2060718 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,19687744 0,20598355 ! positive regulation of lipase activity GO:0060193 115 58 0,000 0,19687744 0,20589537 ! maintenance of location GO:0051235 124 58 0,000 0,19687744 0,20580727 ! nuclear export GO:0051168 110 59 0,000 0,19991014 0,20888814 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,20293148 0,21195451 ! regulation of endocytosis GO:0030100 104 60 0,000 0,20293148 0,21186393 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,20293148 0,21177343 ! regulation of cellular component size GO:0032535 125 61 0,000 0,20594149 0,21482282 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,20594149 0,21473114 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,20594149 0,21463953 ! camera-type eye development GO:0043010 126 61 0,000 0,20594149 0,214548 ! proton transport GO:0015992 117 61 0,000 0,20594149 0,21445654 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,20894021 0,21748655 ! tRNA processing GO:0008033 102 62 0,000 0,20894021 0,21739393 ! regulation of mitosis GO:0007088 112 63 0,000 0,2119277 0,22040842 GO:0051783|regulation of nuclear division, ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,2119277 0,22031463 ! hydrogen transport GO:0006818 121 64 0,000 0,21490399 0,22331367 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,21490399 0,22321873 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,21490399 0,22312386 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,21786912 0,22610631 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,21786912 0,2260103 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,22082314 0,22897747 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,22376608 0,23193064 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,22376608 0,23183229 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,22376608 0,23173401 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,22669799 0,23467084 ! hexose catabolic process GO:0019320 113 68 0,000 0,22669799 0,23457145 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,22669799 0,23447214 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,22669799 0,23437291 ! regulation of lipase activity GO:0060191 137 68 0,000 0,22669799 0,23427377 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,22669799 0,23417471 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,22961891 0,23709171 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,22961891 0,23699154 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,22961891 0,23689146 ! single fertilization GO:0007338 83 69 0,000 0,22961891 0,23679147 ! cell redox homeostasis GO:0045454 114 70 0,000 0,23252887 0,23969115 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,23542793 0,24257715 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,23542793 0,24247489 ! appendage morphogenesis GO:0035107 150 72 0,000 0,23831612 0,24534609 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,23831612 0,24524274 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,23831612 0,24513948 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,23831612 0,24503631 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,23831612 0,24493322 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,23831612 0,24483022 ! appendage development GO:0048736 151 73 0,000 0,24119347 0,24768207 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,24119347 0,24757801 ! regulation of immune effector process GO:0002697 156 73 0,000 0,24119347 0,24747403 ! amino acid transport GO:0006865 148 74 0,000 0,24406004 0,25031011 ! transition metal ion transport GO:0000041 143 75 0,000 0,24691586 0,2531328 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,24691586 0,25302662 ! axon guidance GO:0007411 162 75 0,000 0,24691586 0,25292053 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,24976097 0,2557276 ! learning or memory GO:0007611 161 76 0,000 0,24976097 0,25562047 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,24976097 0,25551343 ! regulation of blood pressure GO:0008217 134 76 0,000 0,24976097 0,25540647 ! amine catabolic process GO:0009310 136 77 0,000 0,25259542 0,25819691 ! neurotransmitter transport GO:0006836 142 77 0,000 0,25259542 0,25808892 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,25259542 0,25798102 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,25259542 0,25787322 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,25259542 0,2577655 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,25259542 0,25765787 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,25541923 0,26042954 ! antigen processing and presentation GO:0019882 117 78 0,000 0,25541923 0,26032089 ! fertilization GO:0009566 99 78 0,000 0,25541923 0,26021234 ! blood coagulation GO:0007596 151 79 0,000 0,25823246 0,26296869 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,25823246 0,26285912 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,25823246 0,26274964 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,25823246 0,26264025 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,25823246 0,26253096 ! negative regulation of organelle organization GO:0010639 181 80 0,000 0,26103513 0,26526989 ! meiosis GO:0007126 143 81 0,000 0,26382729 0,26799588 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,26382729 0,26788449 ! meiotic cell cycle GO:0051321 144 82 0,000 0,26660899 0,27059649 ! exocytosis GO:0006887 153 83 0,000 0,26938025 0,27329566 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,26938025 0,27318221 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,26938025 0,27306886 ! inorganic anion transport GO:0015698 156 83 0,000 0,26938025 0,2729556 ! digestion GO:0007586 130 84 0,000 0,27214111 0,27563878 ! regulation of ligase activity GO:0051340 147 84 0,000 0,27214111 0,27552455 ! hemostasis GO:0007599 165 85 0,000 0,27489162 0,27819397 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,27489162 0,27807877 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,27489162 0,27796367 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,28036173 0,28337762 ! alcohol catabolic process GO:0046164 142 87 0,000 0,28036173 0,28326043 ! nucleosome assembly GO:0006334 126 87 0,000 0,28036173 0,28314333 ! cellular respiration GO:0045333 143 88 0,000 0,28308141 0,28577185 ! sensory perception of smell GO:0007608 117 88 0,000 0,28308141 0,28565381 ! chromatin assembly GO:0031497 128 88 0,000 0,28308141 0,28553587 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,28308141 0,28541802 ! cellular defense response GO:0006968 123 89 0,000 0,28579088 0,28803099 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,28849019 0,29063156 ! response to unfolded protein GO:0006986 139 90 0,000 0,28849019 0,29051176 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,28849019 0,29039206 ! defense response to bacterium GO:0042742 112 91 0,000 0,29117937 0,29297826 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,29385847 0,29555218 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,29652751 0,29811387 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,29652751 0,29799124 ! vitamin metabolic process GO:0006766 153 93 0,000 0,29652751 0,29786871 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,29918654 0,30041625 ! sterol metabolic process GO:0016125 166 94 0,000 0,29918654 0,30029282 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,29918654 0,3001695 ! nucleosome organization GO:0034728 143 95 0,000 0,3018356 0,30270294 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,3018356 0,30257873 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,3018356 0,30245462 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,3018356 0,30233061 ! regulation of T cell activation GO:0050863 175 96 0,000 0,30447471 0,30484907 ! forebrain development GO:0030900 210 98 0,000 0,30972328 0,30997705 ! mRNA transport GO:0051028 185 100 0,000 0,31493253 0,31506149 ! hormone metabolic process GO:0042445 171 100 0,000 0,31493253 0,31493253